PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Glycine	80-83	tripartite motif containing 47	Homo sapiens	84-87
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Glycine	80-83	tripartite motif containing 47	Homo sapiens	84-87
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Glycine	80-83	tripartite motif containing 47	Homo sapiens	84-87
2573600-6	1989	In contrast, the Arg-Gly-Asp-Ser tetrapeptide as well as the monoclonal antibody 7E3 markedly inhibited attachment of endothelial cells to substrate-immobilized fibrinogen, whereas fragment D or E did not.	Glycine	21-24	fibrinogen beta chain	Homo sapiens	161-171
2583408-8	1989	A control antibody, specific for the biologically inactive glycine-extended gastrin/cholecystokinin peptapeptide region, had no significant effect on gastric acid secretion stimulated by gastrin or by gastric distention with nutrients.	Glycine	59-66	gastrin	Canis lupus familiaris	76-83
2623188-0	1989	Non-amidated forms of VIP (glycine-extended VIP and VIP-free acid) have full bioactivity on smooth muscle.	Glycine	27-34	vasoactive intestinal peptide	Homo sapiens	22-25
2690069-5	1989	The sequences of the genes for amylin and the calcitonin gene-related peptides (CGRPs) show strong similarity, especially over their 5" coding regions, where both peptides have a conserved intramolecular disulfide bridge, and also over their 3" coding regions, where the presence of a glycine codon strongly suggests that the carboxyl-terminal residue of amylin, like that of CGRP, is amidated.	Glycine	285-292	calcitonin related polypeptide alpha	Homo sapiens	80-84
2511192-2	1989	Recent reports have demonstrated that a series of probands with severe osteogenesis imperfecta had single base mutations in one of the two structural genes for type I procollagen that substituted amino acids with bulkier side chains for glycine residues and decreased the melting temperature of the triple helix.	Glycine	237-244	collagen type I alpha 2 chain	Homo sapiens	160-178
2572591-0	1989	Glycine to serine substitution in the triple helical domain of pro-alpha 1 (II) collagen results in a lethal perinatal form of short-limbed dwarfism.	Glycine	0-7	collagen type II alpha 1 chain	Homo sapiens	63-88
2480354-10	1989	A synthetic Arg-Gly-Asp-Ser tetrapeptide (RGDS), specific for fibronectin and vitronectin adhesion receptors, inhibited TRH-, EGF-, and TPA-induced GH4 cell stretching and attachment to fibronectin- and vitronectin-coated dishes.	Glycine	16-19	vitronectin	Rattus norvegicus	78-89
2480354-10	1989	A synthetic Arg-Gly-Asp-Ser tetrapeptide (RGDS), specific for fibronectin and vitronectin adhesion receptors, inhibited TRH-, EGF-, and TPA-induced GH4 cell stretching and attachment to fibronectin- and vitronectin-coated dishes.	Glycine	16-19	vitronectin	Rattus norvegicus	203-214
2685120-4	1989	In contrast, lymphokine-mediated agglutination involves interactions between the MAggF cell-binding domain and integrin FN receptors recognizing the Arg-Gly-Asp sequence.	Glycine	153-156	interleukin 2	Homo sapiens	13-23
2557628-6	1989	The A2 and B1 proteins have a modular structure similar to that of the hnRNP protein A1: they contain two CS-RBDs and a glycine-rich auxiliary domain at the carboxyl terminus.	Glycine	120-127	G protein-coupled receptor 162	Homo sapiens	4-13
2623188-0	1989	Non-amidated forms of VIP (glycine-extended VIP and VIP-free acid) have full bioactivity on smooth muscle.	Glycine	27-34	vasoactive intestinal peptide	Homo sapiens	44-47
2623188-0	1989	Non-amidated forms of VIP (glycine-extended VIP and VIP-free acid) have full bioactivity on smooth muscle.	Glycine	27-34	vasoactive intestinal peptide	Homo sapiens	44-47
2623188-2	1989	Two synthetic peptides lacking the amide group: VIP having a carboxyl group at the C-terminus and the intermediate biosynthetic precursor, glycine-extended VIP were compared with VIP itself regarding the ability to inhibit spontaneous activity in smooth muscle strips from rat stomach and human Fallopian tube.	Glycine	139-146	vasoactive intestinal peptide	Rattus norvegicus	156-159
2623188-2	1989	Two synthetic peptides lacking the amide group: VIP having a carboxyl group at the C-terminus and the intermediate biosynthetic precursor, glycine-extended VIP were compared with VIP itself regarding the ability to inhibit spontaneous activity in smooth muscle strips from rat stomach and human Fallopian tube.	Glycine	139-146	vasoactive intestinal peptide	Rattus norvegicus	156-159
2623188-3	1989	Both the glycine-extended VIP and VIP having a carboxyl group at the C-terminus caused a significant and dose-dependent inhibition of smooth muscle activity and displayed dose-response curves similar to VIP.	Glycine	9-16	vasoactive intestinal peptide	Homo sapiens	26-29
2509263-7	1989	Peptides with the sequence arg-gly-asp-ser or gly-arg-gly-asp-ser, which inhibit adhesive interactions mediated by the integrin-binding domain of fibronectin, had no effect on conveyance or accumulation of heparin-coated beads, but the peptide with the sequence gly-arg-gly, a repeated motif in the amino-terminal heparin-binding domain was completely inhibitory.	Glycine	31-34	fibronectin 1	Homo sapiens	146-157
2792654-0	1989	Glycine-extended processing intermediates of gastrin and cholecystokinin in human plasma.	Glycine	0-7	cholecystokinin	Homo sapiens	57-72
2792654-1	1989	The biosynthesis of biologically active gastrin and cholecystokinin (CCK) requires the formation of carboxyl-terminally amidated peptides from glycine-extended precursors of gastrin and CCK.	Glycine	143-150	cholecystokinin	Homo sapiens	52-67
2792654-4	1989	Ingestion of a standard meal induced a biphasic rise in plasma G/CCK-gly concentration, but only the initial increase correlated with gastrin release.	Glycine	69-72	cholecystokinin	Homo sapiens	65-68
2792654-1	1989	The biosynthesis of biologically active gastrin and cholecystokinin (CCK) requires the formation of carboxyl-terminally amidated peptides from glycine-extended precursors of gastrin and CCK.	Glycine	143-150	cholecystokinin	Homo sapiens	69-72
2792654-1	1989	The biosynthesis of biologically active gastrin and cholecystokinin (CCK) requires the formation of carboxyl-terminally amidated peptides from glycine-extended precursors of gastrin and CCK.	Glycine	143-150	cholecystokinin	Homo sapiens	186-189
2792654-2	1989	In previous studies we and others have identified and characterized glycine-extended forms of gastrin (Ggly) and CCK (CCK-gly) in the human gastrointestinal tract.	Glycine	68-75	cholecystokinin	Homo sapiens	118-125
2514250-7	1989	In the course of the erythropoietin therapy, the plasma concentrations of glycine (p less than 0.05) and hydroxyproline (p less than 0.10) of the haemodialysis patients decreased, whereas the concentration of serine increased (p less than 0.05) to approximately normal values.	Glycine	74-81	erythropoietin	Homo sapiens	21-35
2527855-8	1989	Laminin-binding by the alpha beta 1 complex was independent of Arg-Gly-Asp or Tyr-Ile-Gly-Ser-Arg-like sequences, but required the presence of divalent cations.	Glycine	67-70	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	29-35
2813417-1	1989	Myristoyl-CoA:protein N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the cotranslational linkage of myristate to the N-terminal glycine residues of several cellular, viral, and oncoproteins.	Glycine	133-140	N-myristoyltransferase 1	Homo sapiens	22-44
2813417-1	1989	Myristoyl-CoA:protein N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the cotranslational linkage of myristate to the N-terminal glycine residues of several cellular, viral, and oncoproteins.	Glycine	133-140	N-myristoyltransferase 1	Homo sapiens	46-49
2690940-0	1989	Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val-481-Gly-718) to the N-terminal region of the alpha-chain of membrane glycoprotein Ib on intact platelets with bis(sulfosuccinimidyl) suberate.	Glycine	98-101	von Willebrand factor	Homo sapiens	59-80
2794059-4	1989	[15N]Glycine enrichment in both plasma fibronectin and fibrinogen was also quantified.	Glycine	5-12	fibronectin 1	Homo sapiens	39-50
2794059-4	1989	[15N]Glycine enrichment in both plasma fibronectin and fibrinogen was also quantified.	Glycine	5-12	fibrinogen beta chain	Homo sapiens	55-65
2794059-6	1989	In normal subjects, the FSR for plasma fibronectin using 15N enrichment into urinary hippurate was 35.35 +/- 1.46%/d, whereas the Js/V was 4.45 +/- 0.19 micrograms/ml plasma per h. In normal subjects, the FSR for plasma fibronectin using 15N enrichment into free plasma glycine was 14.73 +/- 0.63%/d, whereas the Js/V was 1.98 +/- 0.09 micrograms/ml plasma per h. Early (2-3 d) after burn injury, fibronectin synthesis was increased (Js/V = 5.74 +/- 0.36; P less than 0.05), whereas later after injury, fibronectin synthesis began to decline (Js/V = 3.52 +/- 0.24; P less than 0.05) based on 15N enrichment of urinary hippurate.	Glycine	270-277	fibronectin 1	Homo sapiens	39-50
2608050-2	1989	Bovine preprogastrin comprises 104 amino acids and consists of a signal peptide, a 37 amino acid spacer-sequence, the gastrin-34 sequence followed by an amidation-site (Gly-Arg-Arg), and a C-terminal nonapeptide.	Glycine	169-172	gastrin	Bos taurus	13-20
2674116-7	1989	This sulfur-free signal peptide analog can be labeled with 125I on the C-terminal D-tyrosine and is cleaved by purified hen oviduct signal peptidase between Gly and Lys, the correct site of cleavage of preproparathyroid hormone in vivo.	Glycine	157-160	parathyroid hormone	Homo sapiens	202-227
2673537-3	1989	Endothelial cells exclusively recognize an Arg-Gly-Asp-containing site near the C-terminus of the alpha chain (alpha residues 572-574) but fail to recognize the Arg-Gly-Asp sequence in the N-terminal region of the same chain (alpha residues 95-97).	Glycine	47-50	Fc gamma receptor and transporter	Homo sapiens	98-133
2477372-11	1989	The homologous sequence in the chicken EGF receptor, which binds mouse EGF with a 100-fold lower affinity than the human EGF receptor, contains four amino acid differences including two in the Arg-Gly-Asp-Ser tetramer.	Glycine	197-200	epidermal growth factor receptor	Homo sapiens	39-51
2477372-11	1989	The homologous sequence in the chicken EGF receptor, which binds mouse EGF with a 100-fold lower affinity than the human EGF receptor, contains four amino acid differences including two in the Arg-Gly-Asp-Ser tetramer.	Glycine	197-200	epidermal growth factor receptor	Homo sapiens	121-133
2693157-6	1989	Thus, the two derivatives specifically modified the cellular processing of insulin in cultured fetal hepatocytes, and exerted an insulin-like effect on glycogenesis clearly enhanced through modification of DP-432 by substitution of glycine for proline (DP-640).	Glycine	232-239	insulin	Homo sapiens	129-136
2554286-11	1989	The testis enzyme contains the second of the two putative metal-binding sites (His-Glu-Met-Gly-His) identified in endothelial ACE.	Glycine	91-94	angiotensin I converting enzyme	Homo sapiens	126-129
2777764-6	1989	All were heterozygous single base mutations which led to the substitution of glycine residues in the helical region of the pro-alpha-chains.	Glycine	77-84	PROA	Homo sapiens	123-132
2527855-8	1989	Laminin-binding by the alpha beta 1 complex was independent of Arg-Gly-Asp or Tyr-Ile-Gly-Ser-Arg-like sequences, but required the presence of divalent cations.	Glycine	86-89	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	29-35
2613766-10	1989	Migration over intact FGN was almost totally blocked by 230 microM-Arg-Gly-Asp-Ser (RGDS), a peptide known to interact with integrin-type receptors.	Glycine	71-74	fibrinogen beta chain	Homo sapiens	22-25
2803891-0	1989	Vasopressin and amino acid concentrations in serum following absorption of irrigating fluid containing glycine and ethanol.	Glycine	103-110	arginine vasopressin	Homo sapiens	0-11
2803891-1	1989	Absorption of glycine solution during transurethral resection of the prostate (TURP) changes the serum concentrations of most non-essential amino acids and inhibits diuresis by stimulating release of vasopressin.	Glycine	14-21	arginine vasopressin	Homo sapiens	200-211
2472386-5	1989	The replacement of the C region of hIGF-I with a four-glycine span results in a 30-fold loss of affinity for the type 1 IGF receptor.	Glycine	54-61	insulin like growth factor 1	Homo sapiens	35-41
2765563-8	1989	A synthetic peptide Lys-Thr-Gly-deoxyhypusine-His-Gly-His-Ala-Lys, the amino acid sequence of which corresponds to that surrounding hypusine in eukaryotic initiation factor 4D, was found to display competitive-type inhibition (Ki, 0.44 +/- 0.02 mM) against deoxyhypusine hydroxylase from Chinese hamster ovary cells.	Glycine	28-31	deoxyhypusine hydroxylase	Cricetulus griseus	257-282
2765563-8	1989	A synthetic peptide Lys-Thr-Gly-deoxyhypusine-His-Gly-His-Ala-Lys, the amino acid sequence of which corresponds to that surrounding hypusine in eukaryotic initiation factor 4D, was found to display competitive-type inhibition (Ki, 0.44 +/- 0.02 mM) against deoxyhypusine hydroxylase from Chinese hamster ovary cells.	Glycine	50-53	deoxyhypusine hydroxylase	Cricetulus griseus	257-282
2499585-1	1989	To define determinants of interactions of tissue-type plasminogen activator (t-PA) with plasminogen activator inhibitor type-1 (PAI-1), we utilized site-directed mutagenesis to substitute either threonine or glycine for the active-site serine of tissue-type plasminogen activator.	Glycine	208-215	plasminogen activator, tissue type	Homo sapiens	77-81
2500441-3	1989	Structural studies showed that both IGF-I forms were processed identically, resulting in 70-amino-acid long polypeptides, with intact N-terminal and C-terminal residues of glycine and alanine, respectively.	Glycine	172-179	insulin like growth factor 1	Homo sapiens	36-41
2545728-0	1989	Von Willebrand factor promotes endothelial cell adhesion via an Arg-Gly-Asp-dependent mechanism.	Glycine	68-71	von Willebrand factor	Homo sapiens	0-21
2545728-13	1989	We found that the antibody that recognizes the residues 1,744-1,746, containing the Arg-Gly-Asp sequence, completely inhibit EC adhesion to vWF whereas a second antibody recognizing the adjacent residues 1,740-1,742 (Arg-Gly-Asp-free) is inactive.	Glycine	88-91	von Willebrand factor	Homo sapiens	140-143
2545728-15	1989	This defines the molecular domain on vWF that is specifically recognized by ECs and reaffirms the direct role of the Arg-Gly-Asp sequence as the integrin receptor recognition site also in the vWF molecule.	Glycine	121-124	von Willebrand factor	Homo sapiens	37-40
2545728-15	1989	This defines the molecular domain on vWF that is specifically recognized by ECs and reaffirms the direct role of the Arg-Gly-Asp sequence as the integrin receptor recognition site also in the vWF molecule.	Glycine	121-124	von Willebrand factor	Homo sapiens	192-195
2773809-8	1989	Clustering was also induced by the addition of the GPIIb-IIIa binding domains of fibrinogen--namely, the tetrapeptide Arg-Gly-Asp-Ser on the alpha-chain or the gamma-chain decapeptide gamma 402-411.	Glycine	122-125	fibrinogen beta chain	Homo sapiens	81-91
2735907-11	1989	Like three other members of the family, FL-NCA-3 contains the Arg-Gly-Asp sequence in a position in the N-domain corresponding to complementarity determining region 3 of immunoglobulin.	Glycine	66-69	pregnancy specific beta-1-glycoprotein 5	Homo sapiens	40-48
2552762-5	1989	The new compounds have an acidic function corresponding to the glycine carboxyl of LTD4 linked through a heterocyclic group which is proposed to bind to the LTD4 receptor where the cysteinyl glycine amide bond of LTD4 binds.	Glycine	63-70	cysteinyl leukotriene receptor 1	Homo sapiens	157-170
2773809-8	1989	Clustering was also induced by the addition of the GPIIb-IIIa binding domains of fibrinogen--namely, the tetrapeptide Arg-Gly-Asp-Ser on the alpha-chain or the gamma-chain decapeptide gamma 402-411.	Glycine	122-125	Fc gamma receptor and transporter	Homo sapiens	141-152
2475171-9	1989	The D1.3 energetic epitope of lysozyme involved Gly 22, Gly 117, and Gln 121; the HyHEL-5 epitope consisted of Arg 45 and Arg 68.	Glycine	48-51	lysozyme	Homo sapiens	30-38
2764886-7	1989	The data also demonstrated that human type III procollagen has the same third base preference in codons for glycine, proline and alanine that was previously found with human and chick type I procollagen.	Glycine	108-115	collagen type I alpha 2 chain	Homo sapiens	184-202
2542570-4	1989	Purified p10gag lacks the initiator methionine and has a myristoyl group attached in amide linkage to the N-terminal glycine residue predicted by the second codon of the gag gene.	Glycine	117-124	Pr77	Mouse mammary tumor virus	12-15
2475171-9	1989	The D1.3 energetic epitope of lysozyme involved Gly 22, Gly 117, and Gln 121; the HyHEL-5 epitope consisted of Arg 45 and Arg 68.	Glycine	56-59	lysozyme	Homo sapiens	30-38
2712830-1	1989	Fibronectin, von Willebrand factor, and fibrinogen each bind to the glycoprotein IIb-IIIa complex on activated platelets via an arg-gly-asp-ser (RGDS) sequence present within the adhesive proteins.	Glycine	68-71	fibronectin 1	Homo sapiens	0-11
2469496-8	1989	This antiserum also recognized the EC membrane protein complex eluted from the FN affinity column by an arg-gly-asp (RGD) peptide.	Glycine	108-111	fibronectin 1	Homo sapiens	79-81
2539165-8	1989	Our studies indicate that the final products of bradykinin degradation were the tripeptide Arg-Pro-Pro, one mole each of Ser, Pro, Gly, and Arg, and two moles of phenylalanine.	Glycine	131-134	kininogen 1	Homo sapiens	48-58
2742826-5	1989	There is a chain reversal within residues Asp(7)-Arg(16) such that Phe(8) is brought close to the Arg(16)-Gly(17) peptide bond in the thrombin-peptide complex, as indicated by transferred NOEs between the aromatic ring protons of Phe(8) and the C alpha H protons of Gly(14) and the C gamma H protons of Val(15).	Glycine	106-109	coagulation factor II, thrombin	Homo sapiens	134-142
2742826-5	1989	There is a chain reversal within residues Asp(7)-Arg(16) such that Phe(8) is brought close to the Arg(16)-Gly(17) peptide bond in the thrombin-peptide complex, as indicated by transferred NOEs between the aromatic ring protons of Phe(8) and the C alpha H protons of Gly(14) and the C gamma H protons of Val(15).	Glycine	266-269	coagulation factor II, thrombin	Homo sapiens	134-142
2742827-2	1989	At pH 5.3 and 25 degrees C, the Arg(16)-Gly(17) peptide bonds in both F6 and F8 were cleaved instantaneously in the presence of 0.5 mM thrombin, producing truncated peptides tF6 and tF8 and other peptide fragments.	Glycine	40-43	coagulation factor II, thrombin	Homo sapiens	135-143
2742828-4	1989	Binding of thrombin to peptides F16 and F17, and hence to tF16 and tF17 as a result of the cleavage of the Arg(16)-Gly(17) peptide bond, broadens the proton resonances of residues Asp(7) to Arg(16), suggesting that thrombin interacts specifically with this sequence of residues.	Glycine	115-118	coagulation factor II, thrombin	Homo sapiens	11-19
2742828-8	1989	From incorporation of TRNOE information into distance geometry calculations, Val(12) was found to disrupt the type II beta-turn involving Glu(11) and Gly(12) that is present in complexes of thrombin with normal fibrinogen-like peptides.	Glycine	150-153	coagulation factor II, thrombin	Homo sapiens	190-198
2742828-10	1989	This altered geometry presumably affects the positioning of the Arg(16)-Gly(17) bond in the active site of thrombin.	Glycine	72-75	coagulation factor II, thrombin	Homo sapiens	107-115
2928328-3	1989	(i) Two peptides that inhibit the binding of fibrinogen and other ligands to gpIIb-IIIa, Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val, also inhibited the thrombin-induced tyrosine phosphorylation of this subset of proteins.	Glycine	121-124	coagulation factor II, thrombin	Homo sapiens	177-185
2928328-3	1989	(i) Two peptides that inhibit the binding of fibrinogen and other ligands to gpIIb-IIIa, Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val, also inhibited the thrombin-induced tyrosine phosphorylation of this subset of proteins.	Glycine	121-124	coagulation factor II, thrombin	Homo sapiens	177-185
2928328-3	1989	(i) Two peptides that inhibit the binding of fibrinogen and other ligands to gpIIb-IIIa, Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val, also inhibited the thrombin-induced tyrosine phosphorylation of this subset of proteins.	Glycine	121-124	coagulation factor II, thrombin	Homo sapiens	177-185
2522679-3	1989	A point mutation in the alpha-chain gene was identified that results in the substitution of Gly with Ser in eight Ashkenazi adult GM2 gangliosidosis patients from five different families.	Glycine	92-95	Fc gamma receptor and transporter	Homo sapiens	24-35
2539165-3	1989	Angiotensin-converting enzyme was an effective kininase in mixtures with carboxypeptidase N at physiologic concentration and digested bradykinin to the dipeptides Phe- Arg and Ser-Pro plus the pentapeptide Arg-Pro-Pro-Gly-Phe.	Glycine	218-221	angiotensin I converting enzyme	Homo sapiens	0-29
2539165-3	1989	Angiotensin-converting enzyme was an effective kininase in mixtures with carboxypeptidase N at physiologic concentration and digested bradykinin to the dipeptides Phe- Arg and Ser-Pro plus the pentapeptide Arg-Pro-Pro-Gly-Phe.	Glycine	218-221	kininogen 1	Homo sapiens	134-144
2742826-2	1989	At pH 5.3 and 25 degrees C, the Arg(16)-Gly(17) peptide bonds of both peptides F10 and F13 were cleaved instantaneously in the presence of 0.6 mM thrombin, whereas the cleavage of the Arg(19)-Val(20) peptide bonds in peptides F12, F13, and F14 took over 1 h for completion.	Glycine	40-43	coagulation factor II, thrombin	Homo sapiens	146-154
2705991-4	1989	The main proportion of glycine transport through the low-affinity system is carried out by the ASC System, which appears to be constitutively expressed by the cells.	Glycine	23-30	PYD and CARD domain containing	Homo sapiens	95-98
2764968-3	1989	The canine sequence encodes a preprogastrin of 104 amino acids which consists of a signal peptide, a 37-amino acid prosegment, and a 34-amino acid gastrin sequence, followed by a glycine (the amide donor), and flanked by pairs of arginine residues.	Glycine	179-186	gastrin	Canis lupus familiaris	36-43
2705991-3	1989	The low-affinity component of the transport of glycine can be discriminated as two components, namely System A and System ASC.	Glycine	47-54	PYD and CARD domain containing	Homo sapiens	122-125
2474153-2	1989	CCK-JMV-180 [BOC-Tyr(SO3)-Nle-Gly-Trp-Nle-Asp-2-phenylethylester] at concentrations up to 1 microM did not cause desensitization of enzyme secretion; however, the peptide was able to inhibit CCK-8-induced desensitization.	Glycine	30-33	cholecystokinin	Homo sapiens	0-3
2706569-5	1989	Antibodies against the fibronectin receptor of CHO fibroblasts and short peptides containing the Arg-Gly-Asp sequence greatly reduced PGC adhesion to fibronectin.	Glycine	101-104	progastricsin (pepsinogen C)	Mus musculus	134-137
2914927-2	1989	Juxtaposed to a 26-residue leader peptide, pro-alpha 2(V) exhibits a characteristic cysteine-rich globular region followed by 24 Gly-X-Y repeats which are interrupted by two short non-collagenous sequences.	Glycine	129-132	collagen type V alpha 2 chain	Homo sapiens	47-57
2537118-0	1989	Fibrinogen-endothelial cell interaction in vitro: a pathway mediated by an Arg-Gly-Asp recognition specificity.	Glycine	79-82	fibrinogen beta chain	Homo sapiens	0-10
2914942-0	1989	A single base mutation that converts glycine 907 of the alpha 2(I) chain of type I procollagen to aspartate in a lethal variant of osteogenesis imperfecta.	Glycine	37-44	collagen type I alpha 2 chain	Homo sapiens	76-94
2914942-10	1989	Therefore, the single base substitution that converts glycine 907 in the alpha 2(I) chain to aspartate is solely responsible for the decreased thermal stability of the type I procollagen synthesized by the proband"s fibroblasts.	Glycine	54-61	collagen type I alpha 2 chain	Homo sapiens	168-186
2703819-10	1989	At low Cl (5 mM Cl balanced with NO3), the glycine influx as a function of Na showed the same stoichiometry and Vmax-Na but a decreased affinity of the carrier for Na.	Glycine	43-50	NBL1, DAN family BMP antagonist	Homo sapiens	33-36
2462607-0	1989	CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide.	Glycine	52-55	integrin subunit beta 2	Homo sapiens	11-15
2806936-4	1989	To modify this interaction, we placed a peptide containing the arginine-glycine-aspartic acid sequence that competes for the cellular binding site of fibronectin onto the collagen gels.	Glycine	72-79	fibronectin 1	Homo sapiens	150-161
2489233-4	1989	Although inhibitors of the enkephalin degrading puromycin-insensitive, bestatin-sensitive aminopeptidase (possibly aminopeptidase M) their action is weak (IC50 = 32 microM leucine, 536 microM, glycine) and they might be considered to have a direct antinociceptive effect on opioid receptors.	Glycine	193-200	carboxypeptidase Q	Homo sapiens	90-104
2974038-2	1988	Two sites, the Arg-Gly-Asp-Ser-containing cell attachment domain and a site located in the first 70 kDa of fibronectin, are required for matrix assembly.	Glycine	19-22	fibronectin 1	Homo sapiens	107-118
2552247-4	1989	Tryptic mapping of nexly synthetized alpha-MSH generated two fragments with the following amino acid composition: (T1) Trp, Pro, Lys, Gly, Val and (T2) Tyr, Arg, Phe, His, Ser, Glu.	Glycine	134-137	proopiomelanocortin	Homo sapiens	37-46
2470110-1	1989	The disialogangliosides GD2 and GD3 play a major role in the ability of human melanoma cells to attach to Arg-Gly-Asp-containing substrates such as fibronectin and vitronectin, since pretreatment of these cells with monoclonal antibodies to the oligosaccharide of GD2 and GD3 can inhibit their attachment and spreading on such adhesive proteins.	Glycine	110-113	fibronectin 1	Homo sapiens	148-159
2727382-7	1989	Since triplets of the Gly-Pro-X-type released by the TPP 4 are ideal substrates for DPP II, the integrated action of tripeptidyl and dipeptidyl peptidases could make a novel contribution to the renal depolymerization and reabsorption of polypeptides, in particular the proline-rich, collagen-derived sequences that possess repeating-triplet primary structures.	Glycine	22-25	dipeptidylpeptidase 7	Rattus norvegicus	84-90
2617855-4	1989	Glycine and GABA were highest in the inner plexiform layer, with increasing concentrations through the INL, and were relatively high in the GCL.	Glycine	0-7	germ cell-less 1, spermatogenesis associated	Rattus norvegicus	140-143
2719946-5	1989	The peptide was purified by rechromatography and subjected to Edman degradation which showed that Gly-558 of human prothrombin had been replaced by Val.	Glycine	98-101	coagulation factor II, thrombin	Homo sapiens	115-126
2461939-2	1988	The amino acid sequence of BSP contains an Arg-Gly-Asp (RGD) sequence which confers to the protein cell binding properties (Oldberg, A., Franzen, A., and Heinegard, D. (1988) J. Biol.	Glycine	47-50	integrin-binding sialoprotein	Rattus norvegicus	27-30
2844517-2	1988	Replacement of the naturally-occurring Gly with D-Trp at position 12 in the PTH antagonists [Tyr34]bPTH-(7-34)NH2 and [Nle8,18,Tyr34]bPTH-(7-34)NH2 increased in vitro receptor affinity.	Glycine	39-42	parathyroid hormone	Homo sapiens	76-79
3198624-4	1988	262, 14737-14744), we identified a single-base mutation that converted the glycine at position 748 of the alpha 1 chain of type I procollagen to a cysteine in a proband with a lethal variant of osteogenesis imperfecta.	Glycine	75-82	collagen type I alpha 2 chain	Homo sapiens	123-141
3198635-3	1988	The mature BSP has a molecular mass of 33,600 and contains predominantly glutamic acid and glycine residues, which constitute 32% of all residues.	Glycine	91-98	integrin-binding sialoprotein	Rattus norvegicus	11-14
3198635-6	1988	BSP contains an Arg-Gly-Asp sequence, which presumably is responsible for its cell binding properties (Oldberg, A., Franzen, A., Heinegard, D., Pierschbacher, M., and Ruoslahti, E. (1988) J. Biol.	Glycine	20-23	integrin-binding sialoprotein	Rattus norvegicus	0-3
2474313-1	1988	EBNA-1 is a nuclear antigen of lymphocytes infected by Epstein-Barr virus and whose size polymorphism correlates only with the strain of infecting virus and the length of the glycine-alanine copolymer encoded by the third internal repeat of the viral genome.	Glycine	175-183	EBNA-1	Human gammaherpesvirus 4	0-6
2848742-8	1988	Attachment to and syncytia formation on fibronectin was blocked by the addition of the R-G-D-S-containing peptide, Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	115-118	fibronectin 1	Homo sapiens	40-51
2848742-8	1988	Attachment to and syncytia formation on fibronectin was blocked by the addition of the R-G-D-S-containing peptide, Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	123-126	fibronectin 1	Homo sapiens	40-51
2485226-9	1988	Moreover, they provide evidence that the Arg-Gly-Asp sequence is the only, or essential, GP IIb-IIIa binding site in the vWF molecule.	Glycine	45-48	LOW QUALITY PROTEIN: von Willebrand factor	Oryctolagus cuniculus	121-124
2459313-4	1988	Following the peak of incorporation, glycine-derived radioactivity in the MAG peptide backbone declined several-fold during the first week and was then metabolically stable (half-life much greater than 1 month).	Glycine	37-44	myelin-associated glycoprotein	Rattus norvegicus	74-77
2459313-7	1988	The rates of incorporation of labeled glycine, fucose, and sulfate into MAG all decreased approximately 12-fold between 20 days of age and adulthood, a finding providing further evidence for concerted turnover of the entire molecule.	Glycine	38-45	myelin-associated glycoprotein	Rattus norvegicus	72-75
2460346-0	1988	Anti-(Arg-Gly-Asp-Ser) antibody and its interaction with fibronectin, fibrinogen and platelets.	Glycine	10-13	fibronectin 1	Homo sapiens	57-68
2460346-0	1988	Anti-(Arg-Gly-Asp-Ser) antibody and its interaction with fibronectin, fibrinogen and platelets.	Glycine	10-13	fibrinogen beta chain	Homo sapiens	70-80
2460346-1	1988	An antibody population recognizing the sequence Arg-Gly-Asp-Ser (RGDS) in fibronectin, anti-(RGDS)N, was isolated by immunoadsorption.	Glycine	52-55	fibronectin 1	Homo sapiens	74-85
3170576-7	1988	This protein did, however, exhibit very low amidolytic activity (approximately 5,000 IU/mg) on the u-PA-specific synthetic substrate pyroglu-Gly-Arg-p-nitroanilide, very low plasminogen-dependent fibrinolytic activity on 125I-labeled fibrin coated plates, and directly activated 125I-labeled plasminogen following Michaelis-Menten kinetics with high affinity, Km = 0.72 microM and low turnover number, kcat = 0.0005 s-1.	Glycine	141-144	plasminogen activator, urokinase	Homo sapiens	99-103
2971661-1	1988	Neural cells in culture (NG-108, PC12, chick dorsal root ganglion, chick spinal cord, and rat astrocytes) bind laminin with an apparent Kd of congruent to 10(-9) M. Laminin affinity chromatography of chick brain membranes washed with 150 mM NaCl and eluted with 0.2 M glycine buffer, pH 3.5, yields a single protein with an apparent molecular mass of 67 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions.	Glycine	268-275	laminin, beta 2 (laminin S)	Gallus gallus	165-172
3238697-0	1988	Characterization of peptidylglycine alpha-amidating activities in rat pituitary, brain and small intestine using glycine-extended C-terminal analogues of vasoactive intestinal polypeptide as substrate.	Glycine	28-35	vasoactive intestinal peptide	Rattus norvegicus	154-187
3238697-5	1988	Desamide VIP-Gly was proved to be a potent inhibitor of the alpha-amidating activities from the tissues, but VIP was not, indicating that the alpha-amidating enzymes from these tissues in common have a recognition site for the C-terminal glycine of the glycine-extended precursor regardless of the length and nature of the sequence.	Glycine	13-16	vasoactive intestinal peptide	Rattus norvegicus	9-12
3238697-5	1988	Desamide VIP-Gly was proved to be a potent inhibitor of the alpha-amidating activities from the tissues, but VIP was not, indicating that the alpha-amidating enzymes from these tissues in common have a recognition site for the C-terminal glycine of the glycine-extended precursor regardless of the length and nature of the sequence.	Glycine	238-245	vasoactive intestinal peptide	Rattus norvegicus	9-12
3238697-5	1988	Desamide VIP-Gly was proved to be a potent inhibitor of the alpha-amidating activities from the tissues, but VIP was not, indicating that the alpha-amidating enzymes from these tissues in common have a recognition site for the C-terminal glycine of the glycine-extended precursor regardless of the length and nature of the sequence.	Glycine	253-260	vasoactive intestinal peptide	Rattus norvegicus	9-12
3146495-4	1988	Since plasma serine is primarily produced in the kidneys from glycine, this suggests that insulin affects the regulation of the serine-glycine metabolic pathway.	Glycine	62-69	insulin	Homo sapiens	90-97
3146495-4	1988	Since plasma serine is primarily produced in the kidneys from glycine, this suggests that insulin affects the regulation of the serine-glycine metabolic pathway.	Glycine	135-142	insulin	Homo sapiens	90-97
3146495-5	1988	In turn, measurement of urinary serine and glycine may provide a useful gauge of insulin activity in the tissues, including the kidneys.	Glycine	43-50	insulin	Homo sapiens	81-88
2972276-7	1988	Using purified endopeptidase 24.11, we identified seven sites of hydrolysis in unlabelled alpha-hANP: the bonds Arg-4-Ser-5, Cys-7-Phe-8, Arg-11-Met-12, Arg-14-Ile-15, Gly-16-Ala-17, Gly-20-Leu-21 and Ser-25-Phe-26.	Glycine	168-171	natriuretic peptide A	Homo sapiens	96-100
3071528-2	1988	This alpha-thrombin-catalyzed proteolysis of protein Z occurred at a single peptide linkage, between Arg-365 and Gly-366, located in the COOH-terminal portion.	Glycine	113-116	coagulation factor II, thrombin	Homo sapiens	11-19
3382697-5	1988	The high frequency and clustering of proline and glycine residues in estrogen receptor, progesterone receptor and glucose-6-phosphate dehydrogenase suggests that the translating ribosomes may slow down during synthesis of these proteins due to limiting levels of these tRNAs in E2-deprived uteri.	Glycine	49-56	estrogen receptor 1	Homo sapiens	69-86
3166991-3	1988	The previous suggestion that there is a hairpin loop involving residues Gly(12) to Val(15) in the A alpha chain of human fibrinogen is supported by the slow backbone NH exchange rates of Gly(14) and Val(15), by an unusually small NH chemical shift of Val(15), and by strong sequential NOE"s involving this region in F10.	Glycine	72-75	fibrinogen beta chain	Homo sapiens	121-131
3166991-4	1988	This local chain fold within residues Asp(7) to Val(20) may place the distant Phe residue near the Arg(16)-Gly(17) peptide bond which is cleaved by thrombin.	Glycine	107-110	coagulation factor II, thrombin	Homo sapiens	148-156
2453507-2	1988	We have generated antibodies against a synthetic peptide corresponding to the sequence of human von Willebrand factor (vWF) between residues Glu1737-Ser1750 which includes the Arg-Gly-Asp sequence common to several adhesive molecules.	Glycine	180-183	von Willebrand factor	Homo sapiens	96-117
2453507-2	1988	We have generated antibodies against a synthetic peptide corresponding to the sequence of human von Willebrand factor (vWF) between residues Glu1737-Ser1750 which includes the Arg-Gly-Asp sequence common to several adhesive molecules.	Glycine	180-183	von Willebrand factor	Homo sapiens	119-122
2897363-0	1988	Arginine for glycine substitution in the triple-helical domain of the products of one alpha 2(I) collagen allele (COL1A2) produces the osteogenesis imperfecta type IV phenotype.	Glycine	13-20	collagen type I alpha 2 chain	Homo sapiens	86-105
2897363-0	1988	Arginine for glycine substitution in the triple-helical domain of the products of one alpha 2(I) collagen allele (COL1A2) produces the osteogenesis imperfecta type IV phenotype.	Glycine	13-20	collagen type I alpha 2 chain	Homo sapiens	114-120
3131325-4	1988	Amino-terminal sequence of CT14 was determined to be Ser-Ser-Pro-Gly-Ser-Pro-Gly-Thr-Pro-Gly-Ser-Arg-Ser-Arg-X-Pro-Ser-Leu-Pr o.	Glycine	65-68	sarcoma antigen 1	Homo sapiens	27-31
3065456-0	1988	Molecular cloning, physical mapping and expression of the bet genes governing the osmoregulatory choline-glycine betaine pathway of Escherichia coli.	Glycine	105-112	putative DNA recombination protein Bet	Escherichia coli	58-61
3177558-5	1988	One available thrombin preparation when diluted to 100 U/ml had a glycine concentration associated with previous retinal electroretinography changes.	Glycine	66-73	coagulation factor II, thrombin	Homo sapiens	14-22
2458338-1	1988	The cell surface receptor for fibronectin is a heterodimeric membrane protein that recognizes an Arg-Gly-Asp sequence in fibronectin and that requires cations such as Mg2+ or Ca2+ for binding to fibronectin.	Glycine	101-104	fibronectin 1	Homo sapiens	30-41
2458338-1	1988	The cell surface receptor for fibronectin is a heterodimeric membrane protein that recognizes an Arg-Gly-Asp sequence in fibronectin and that requires cations such as Mg2+ or Ca2+ for binding to fibronectin.	Glycine	101-104	fibronectin 1	Homo sapiens	121-132
2458338-1	1988	The cell surface receptor for fibronectin is a heterodimeric membrane protein that recognizes an Arg-Gly-Asp sequence in fibronectin and that requires cations such as Mg2+ or Ca2+ for binding to fibronectin.	Glycine	101-104	fibronectin 1	Homo sapiens	121-132
2458338-8	1988	The increased fibronectin receptor activity in the presence of Mn2+ appeared to be due to an increase in the affinity of the receptor for the Arg-Gly-Asp sequence because a 110-kDa cell attachment fragment and a synthetic hexapeptide containing the Arg-Gly-Asp sequence inhibited liposome binding more effectively in the presence of Mn2+ than in the presence of Ca2+/Mg2+.	Glycine	146-149	fibronectin 1	Homo sapiens	14-25
2458338-8	1988	The increased fibronectin receptor activity in the presence of Mn2+ appeared to be due to an increase in the affinity of the receptor for the Arg-Gly-Asp sequence because a 110-kDa cell attachment fragment and a synthetic hexapeptide containing the Arg-Gly-Asp sequence inhibited liposome binding more effectively in the presence of Mn2+ than in the presence of Ca2+/Mg2+.	Glycine	253-256	fibronectin 1	Homo sapiens	14-25
3417645-2	1988	The platelet membrane glycoprotein IIb-IIIa complex (GPIIb-IIIa) recognizes peptides containing the amino acid sequence Arg-Gly-Asp, a sequence present at two locations in the alpha chain of fibrinogen.	Glycine	124-127	fibrinogen beta chain	Homo sapiens	191-201
3146495-3	1988	Interestingly, when expressed in terms of mol/g of creatinine, the normalization of serine excretion brought about by insulin was roughly equal to the normalization of glycine excretion brought about by insulin (-0.39 mM/g of creatinine vs. + 0.33 mM/g of creatinine over 24 h).	Glycine	168-175	insulin	Homo sapiens	203-210
3253183-0	1988	[Studies on the stability of ternary complexes of glycine and DL-alanine with Cu(II), Ni(II), Co(II) and Zn(II)].	Glycine	50-57	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	94-100
3240982-2	1988	The predominant amino acids in the phospholipase A2 were cysteine, glycine, arginine, and lysine, suggesting that it is a basic one.	Glycine	67-74	phospholipase A2 group IB	Homo sapiens	35-51
3191112-3	1988	At least two well-defined sequences in fibrinogen, Arg-Gly-Asp sequence of A alpha 95-97 and A alpha 572-574 and gamma 400-411, have been shown to interact with glycoprotein IIb-IIIa.	Glycine	55-58	fibrinogen beta chain	Homo sapiens	39-49
2844950-6	1988	All the alpha-MSH and its glycine-extended precursor ACTH(1-14) were of low molecular weight, mainly non- or mono-acetylated forms, but significant amounts of diacetylated analogues were also present.	Glycine	26-33	proopiomelanocortin	Homo sapiens	8-17
2844950-6	1988	All the alpha-MSH and its glycine-extended precursor ACTH(1-14) were of low molecular weight, mainly non- or mono-acetylated forms, but significant amounts of diacetylated analogues were also present.	Glycine	26-33	proopiomelanocortin	Homo sapiens	53-57
2968824-2	1988	The cell attachment site of fibronectin with its crucial arg-gly-asp(-ser) [RGD(S)]sequence is involved in these bindings.	Glycine	61-64	fibronectin 1	Homo sapiens	28-39
3049246-4	1988	Cleavage of the pre-pro alpha factor leader sequence in vivo results in the secretion of a 70-aa recombinant IGF-I molecule with the native N-terminal glycine residue.	Glycine	151-158	insulin like growth factor 1	Homo sapiens	109-114
3202961-1	1988	Guanidinobenzoatase is a cell surface protease associated with cells capable of migration, this enzyme is trypsin-like and cleaves the link peptide Gly-Arg-Gly-Asp of fibronectin.	Glycine	148-151	fibronectin 1	Homo sapiens	167-178
3286012-2	1988	Site-specific deletion of the putative recognition sequence Arg-Gly-Asp-Ser or an Asp-to-Glu mutation decreased the adhesive activity of fibronectin fusion proteins expressed in E. coli by greater than or equal to 97%.	Glycine	64-67	fibronectin 1	Homo sapiens	137-148
3202961-1	1988	Guanidinobenzoatase is a cell surface protease associated with cells capable of migration, this enzyme is trypsin-like and cleaves the link peptide Gly-Arg-Gly-Asp of fibronectin.	Glycine	156-159	fibronectin 1	Homo sapiens	167-178
2966812-5	1988	The cytoadhesive tetrapeptide portion of fibronectin, Arg-Gly-Asp-Ser (250-1,000 micrograms/ml), released 1.94 +/- 0.10 micrograms/ml of elastase from 10(7) neutrophils, in contrast to the lack of release by the control hexapeptide, Arg-Gly-Tyr-Ser-Leu-Gly.	Glycine	58-61	fibronectin 1	Homo sapiens	41-52
3409865-3	1988	The 346 kd Mr polyprotein is cleaved by a 49 kd Mr virus-encoded proteinase at five different sites between the dipeptides Gln-Ser or Gln-Gly.	Glycine	138-141	polyprotein	Tobacco etch virus	14-25
2966812-5	1988	The cytoadhesive tetrapeptide portion of fibronectin, Arg-Gly-Asp-Ser (250-1,000 micrograms/ml), released 1.94 +/- 0.10 micrograms/ml of elastase from 10(7) neutrophils, in contrast to the lack of release by the control hexapeptide, Arg-Gly-Tyr-Ser-Leu-Gly.	Glycine	237-240	fibronectin 1	Homo sapiens	41-52
3365244-7	1988	Kinetic analysis revealed that the two systems operated glycine transport with the same Km of 1.6 mM, a value unusually high for system ASC.	Glycine	56-63	PYD and CARD domain containing	Homo sapiens	136-139
3357887-6	1988	Intron 3 is located at codon 166 (glycine) at the same nucleotide position as intron 1 in the GAPDH gene from the nematode Caenorhabditis elegans, suggesting that this intron was present in the parental GAPDH gene from which these two modern descendants originated.	Glycine	34-41	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	Zea mays	94-99
3280121-3	1988	Examining fractionated mononuclear cells from bone marrow or peripheral blood, an N-ras mutation at position 13 was observed in one patient with overt leukemia, resulting in a base change from GGT to TGT thus converting glycine to cysteine.	Glycine	220-227	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	200-203
3286820-11	1988	A short peptide derived from fibronectin"s cell-binding domain (Arg-Gly-Asp-Ser) also greatly reduced neurite outgrowth.	Glycine	68-71	fibronectin 1	Homo sapiens	29-40
3357887-6	1988	Intron 3 is located at codon 166 (glycine) at the same nucleotide position as intron 1 in the GAPDH gene from the nematode Caenorhabditis elegans, suggesting that this intron was present in the parental GAPDH gene from which these two modern descendants originated.	Glycine	34-41	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	Zea mays	203-208
2451243-9	1988	One fibronectin-like repeat contains a single Arg-Gly-Asp sequence.	Glycine	50-53	fibronectin 1	Homo sapiens	4-15
2835797-0	1988	Pro-opiomelanocortin-derived peptides in the pig pituitary: alpha- and gamma 1-melanocyte-stimulating hormones and their glycine-extended forms.	Glycine	121-128	pro-opiomelanocortin	Sus scrofa	0-20
2835797-6	1988	In contrast only one fourth to one third of the N-terminal part of POMC (N-POMC) was processed to amidated gamma-MSH and its C-terminal glycine-extended precursor.	Glycine	136-143	pro-opiomelanocortin	Sus scrofa	67-71
2835797-6	1988	In contrast only one fourth to one third of the N-terminal part of POMC (N-POMC) was processed to amidated gamma-MSH and its C-terminal glycine-extended precursor.	Glycine	136-143	pro-opiomelanocortin	Sus scrofa	73-79
2962643-1	1988	A one-chain recombinant tissue-type plasminogen activator (EC 2.4.31.-) (tPA) analogue was constructed in which Arg-275 of the activation site was changed to Gly by site-directed mutagenesis.	Glycine	158-161	plasminogen activator, tissue type	Homo sapiens	24-57
3341776-5	1988	Elevation of serum CaBP was not observed when calcium in the dosing solution was omitted or replaced by either glucose or glycine.	Glycine	122-129	S100 calcium binding protein G	Homo sapiens	19-23
3124821-10	1988	Unlike the carbonic anhydrase II isoenzyme, which has a blocked N-terminus, the high-Mr enzyme has a free glycine residue at its N-terminus.	Glycine	106-113	carbonic anhydrase 2	Ovis aries	11-32
3068006-2	1988	Cells capable of attachment and growth in 5 mM concentrations of a peptide having the sequence Gly-Arg-Gly-Asp-Ser-Pro overproduce the cell surface receptor for fibronectin.	Glycine	95-98	fibronectin 1	Homo sapiens	161-172
3068006-2	1988	Cells capable of attachment and growth in 5 mM concentrations of a peptide having the sequence Gly-Arg-Gly-Asp-Ser-Pro overproduce the cell surface receptor for fibronectin.	Glycine	103-106	fibronectin 1	Homo sapiens	161-172
2466737-6	1988	The vitronectin receptor is involved in the adhesion of endothelial cells to Arg-Gly-Asp-containing immobilized proteins such as vitronectin, fibrinogen, and von Willebrand factor.	Glycine	81-84	fibrinogen beta chain	Homo sapiens	142-152
3693352-1	1987	Peptides containing the tripeptide sequence Arg-Gly-Asp can duplicate or inhibit the cell attachment-promoting effects of fibronectin and vitronectin.	Glycine	48-51	fibronectin 1	Homo sapiens	122-133
2963329-6	1988	FN bound appreciably to this column and was eluted much more efficiently by a solution of Arg-Gly-Asp-Ser-containing peptide than by a solution of related but inactive Arg-Gly-Glu-Ser-containing peptide.	Glycine	94-97	fibronectin 1	Homo sapiens	0-2
2963329-6	1988	FN bound appreciably to this column and was eluted much more efficiently by a solution of Arg-Gly-Asp-Ser-containing peptide than by a solution of related but inactive Arg-Gly-Glu-Ser-containing peptide.	Glycine	172-175	fibronectin 1	Homo sapiens	0-2
3693352-2	1987	Peptides analogous to a prototype peptide, Gly-Arg-Gly-Asp-Ser-Pro-Cys, the sequence of which was taken from the cell attachment site of fibronectin, were assayed for their relative abilities to inhibit the attachment of cells to a fibronectin or vitronectin substrate.	Glycine	43-46	fibronectin 1	Homo sapiens	137-148
2961770-1	1987	Keratinocyte attachment to fibronectin (FN) substrata was inhibited by the peptide Gly-Arg-Gly-Asp-Ser-Pro-Cys, but not by the variant peptide Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	83-86	fibronectin 1	Homo sapiens	27-38
3677088-7	1987	1H-NMR analyses of Friend leukemia cell tumor extracts also indicated, 6 h after tumor injection with TNF: (a) elevated choline levels (9X); (b) a 19-fold increase in the ratio [choline]/[phosporylcholine]; (c) elevated (1.4X) levels of lactic acid; and (d) a 1.6-fold decrease in the [taurine]/[glycine] ratio.	Glycine	296-303	tumor necrosis factor	Mus musculus	102-105
3500868-8	1987	Short synthetic peptides containing the sequence Arg-Gly-Asp-Ser effectively inhibited thrombin-dependent platelet adhesion to vWf substrates but had no effect on ristocetin-dependent adhesion.	Glycine	53-56	coagulation factor II, thrombin	Homo sapiens	87-95
3500868-8	1987	Short synthetic peptides containing the sequence Arg-Gly-Asp-Ser effectively inhibited thrombin-dependent platelet adhesion to vWf substrates but had no effect on ristocetin-dependent adhesion.	Glycine	53-56	von Willebrand factor	Homo sapiens	127-130
3500868-9	1987	Substrates composed of synthetic peptides containing the Arg-Gly-Asp-Ser sequence supported thrombin-dependent adhesion but did not support ristocetin-dependent adhesion.	Glycine	61-64	coagulation factor II, thrombin	Homo sapiens	92-100
2961770-1	1987	Keratinocyte attachment to fibronectin (FN) substrata was inhibited by the peptide Gly-Arg-Gly-Asp-Ser-Pro-Cys, but not by the variant peptide Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	83-86	fibronectin 1	Homo sapiens	40-42
2961770-1	1987	Keratinocyte attachment to fibronectin (FN) substrata was inhibited by the peptide Gly-Arg-Gly-Asp-Ser-Pro-Cys, but not by the variant peptide Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	91-94	fibronectin 1	Homo sapiens	27-38
2961770-1	1987	Keratinocyte attachment to fibronectin (FN) substrata was inhibited by the peptide Gly-Arg-Gly-Asp-Ser-Pro-Cys, but not by the variant peptide Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	91-94	fibronectin 1	Homo sapiens	40-42
2961770-1	1987	Keratinocyte attachment to fibronectin (FN) substrata was inhibited by the peptide Gly-Arg-Gly-Asp-Ser-Pro-Cys, but not by the variant peptide Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	91-94	fibronectin 1	Homo sapiens	27-38
2961770-1	1987	Keratinocyte attachment to fibronectin (FN) substrata was inhibited by the peptide Gly-Arg-Gly-Asp-Ser-Pro-Cys, but not by the variant peptide Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	91-94	fibronectin 1	Homo sapiens	40-42
3689402-6	1987	Sequence analysis of cyanogen bromide peptides derived from methyl isocyanate-blocked lipid extract material produced two peptides which extended the amino acid sequence of SP-B to residue 79, which appears to be a glycine.	Glycine	215-222	surfactant protein B	Bos taurus	173-177
2889486-0	1987	Localization of a collagen-interactive domain of human von Willebrand factor between amino acid residues Gly 911 and Glu 1,365.	Glycine	105-108	von Willebrand factor	Homo sapiens	55-76
3667599-0	1987	A point mutation in a type I procollagen gene converts glycine 748 of the alpha 1 chain to cysteine and destabilizes the triple helix in a lethal variant of osteogenesis imperfecta.	Glycine	55-62	collagen type I alpha 2 chain	Homo sapiens	22-40
3676250-2	1987	After IgG affinity purification of the fusion proteins from the growth medium of Staphylococcus aureus or Escherichia coli, native IGF-I was released by cleavage of an Asn-Gly peptide bond with hydroxylamine.	Glycine	172-175	insulin like growth factor 1	Homo sapiens	131-136
2823804-1	1987	Enzyme activity capable of converting the glycine-extended substance P precursor, substance P-Gly12, into substance P was purified from human cerebrospinal fluid.	Glycine	42-49	tachykinin precursor 1	Homo sapiens	59-70
2823804-1	1987	Enzyme activity capable of converting the glycine-extended substance P precursor, substance P-Gly12, into substance P was purified from human cerebrospinal fluid.	Glycine	42-49	tachykinin precursor 1	Homo sapiens	82-93
2823804-1	1987	Enzyme activity capable of converting the glycine-extended substance P precursor, substance P-Gly12, into substance P was purified from human cerebrospinal fluid.	Glycine	42-49	tachykinin precursor 1	Homo sapiens	82-93
2889366-0	1987	Glycine-extended progastrin processing intermediates: accumulation and cosecretion with gastrin.	Glycine	0-7	gastrin	Canis lupus familiaris	20-27
2889366-3	1987	Glycine-extended progastrin processing intermediates (G-Gly) accumulated rapidly in G-cells cultured in ascorbate-deficient media, exhibiting a fourfold increase over a 51-h culture period, while gastrin content fell to less than half of the initial level.	Glycine	0-7	gastrin	Canis lupus familiaris	20-27
2958239-6	1987	Several other organic solutes (proline, glycine, trimethylamine N-oxide, glycerol, and myo-inositol) that afford cryoprotection to PFK, an effect enhanced by the addition of zinc, do not stabilize the enzyme during air-drying, even if zinc is present.	Glycine	40-47	ATP-dependent 6-phosphofructokinase, muscle type	Oryctolagus cuniculus	131-134
2957232-5	1987	It is monomeric with a tendency to dimerize and appears to be distinct from the cell surface fibronectin receptors which interact with the Arg-Gly-Asp recognition site in the fibronectin molecule.	Glycine	143-146	fibronectin 1	Homo sapiens	93-104
2957232-5	1987	It is monomeric with a tendency to dimerize and appears to be distinct from the cell surface fibronectin receptors which interact with the Arg-Gly-Asp recognition site in the fibronectin molecule.	Glycine	143-146	fibronectin 1	Homo sapiens	175-186
2443507-1	1987	The disialogangliosides GD2 and GD3 play a major role in the ability of human melanoma cells to attach to Arg-Gly-Asp-containing substrates such as fibronectin and vitronectin, since pretreatment of these cells with monoclonal antibodies to the oligosaccharide of GD2 and GD3 can inhibit their attachment and spreading on such adhesive proteins.	Glycine	110-113	fibronectin 1	Homo sapiens	148-159
2443508-0	1987	Human osteosarcoma cells resistant to detachment by an Arg-Gly-Asp-containing peptide overproduce the fibronectin receptor.	Glycine	59-62	fibronectin 1	Homo sapiens	102-113
2443508-2	1987	Cells capable of attachment and growth in 5-mM concentrations of a peptide having the sequence Gly-Arg-Gly-Asp-Ser-Pro overproduce the cell surface receptor for fibronectin.	Glycine	95-98	fibronectin 1	Homo sapiens	161-172
2443508-2	1987	Cells capable of attachment and growth in 5-mM concentrations of a peptide having the sequence Gly-Arg-Gly-Asp-Ser-Pro overproduce the cell surface receptor for fibronectin.	Glycine	103-106	fibronectin 1	Homo sapiens	161-172
2443508-4	1987	In agreement with the resistance of the selected cells to detachment by the peptide, 25-fold more Arg-Gly-Asp-containing peptide is required to prevent the attachment of these cells to fibronectin-coated surfaces than is needed to inhibit the attachment of MG-63 cells to the same substrate.	Glycine	102-105	fibronectin 1	Homo sapiens	185-196
2820123-8	1987	In contrast to the variable regions, other sequences and the overall VP2 structure (including cysteine, proline, and glycine residues) were highly conserved.	Glycine	117-124	VP2	Bluetongue virus	69-72
2886501-7	1987	The uptake of glycine was increased 25-50% by either insulin or IGF-I.	Glycine	14-21	insulin	Homo sapiens	53-60
2886501-7	1987	The uptake of glycine was increased 25-50% by either insulin or IGF-I.	Glycine	14-21	insulin like growth factor 1	Homo sapiens	64-69
2886501-8	1987	The response to insulin or IGF-I on glycine uptake is gradual and concentration dependent.	Glycine	36-43	insulin	Homo sapiens	16-23
2886501-8	1987	The response to insulin or IGF-I on glycine uptake is gradual and concentration dependent.	Glycine	36-43	insulin like growth factor 1	Homo sapiens	27-32
2886501-13	1987	Because of the implication that glycine responds as a neuroactive amino acid in Y79 cells these studies suggest that insulin and IGF-I may influence neuroactivity in the human retina by regulating the transport of glycine.	Glycine	32-39	insulin	Homo sapiens	117-124
2886501-13	1987	Because of the implication that glycine responds as a neuroactive amino acid in Y79 cells these studies suggest that insulin and IGF-I may influence neuroactivity in the human retina by regulating the transport of glycine.	Glycine	32-39	insulin like growth factor 1	Homo sapiens	129-134
2886501-13	1987	Because of the implication that glycine responds as a neuroactive amino acid in Y79 cells these studies suggest that insulin and IGF-I may influence neuroactivity in the human retina by regulating the transport of glycine.	Glycine	214-221	insulin	Homo sapiens	117-124
2886501-13	1987	Because of the implication that glycine responds as a neuroactive amino acid in Y79 cells these studies suggest that insulin and IGF-I may influence neuroactivity in the human retina by regulating the transport of glycine.	Glycine	214-221	insulin like growth factor 1	Homo sapiens	129-134
3496337-6	1987	An 18-residue synthetic peptide corresponding to residues 4-21 of cystatin C did not inhibit papain but was cleaved at the same Gly-Gly bond as cystatin C.	Glycine	128-131	cystatin C	Gallus gallus	66-76
3301403-4	1987	The glycines at A1, B8 and B23 allow the chain to assume the characteristic tertiary interactions of the insulin fold and although polypeptide chains are shorter at the COOH-termini of the A and B chains and extended at the NH2-terminus of the B chain, the insulin-like tertiary structure can still be assumed.	Glycine	4-12	insulin	Homo sapiens	105-112
3301403-4	1987	The glycines at A1, B8 and B23 allow the chain to assume the characteristic tertiary interactions of the insulin fold and although polypeptide chains are shorter at the COOH-termini of the A and B chains and extended at the NH2-terminus of the B chain, the insulin-like tertiary structure can still be assumed.	Glycine	4-12	insulin	Homo sapiens	257-264
3496337-6	1987	An 18-residue synthetic peptide corresponding to residues 4-21 of cystatin C did not inhibit papain but was cleaved at the same Gly-Gly bond as cystatin C.	Glycine	132-135	cystatin C	Gallus gallus	66-76
3496337-9	1987	We conclude that the peptidyl bond of the conserved glycine residue in human cystatin C and chicken cystatin probably is part of a substrate-like inhibitory reactive site of these cysteine proteinase inhibitors of the cystatin superfamily and that this may be true also for other inhibitors of this superfamily.	Glycine	52-59	cystatin C	Gallus gallus	77-85
3496337-9	1987	We conclude that the peptidyl bond of the conserved glycine residue in human cystatin C and chicken cystatin probably is part of a substrate-like inhibitory reactive site of these cysteine proteinase inhibitors of the cystatin superfamily and that this may be true also for other inhibitors of this superfamily.	Glycine	52-59	cystatin C	Gallus gallus	100-108
2956269-4	1987	The RGDS tetrapeptide (arg-gly-asp-ser) from the cell attachment domain of fibronectin can specifically block attachment and outgrowth on both fibronectin- and laminin-coated substrates.	Glycine	27-30	fibronectin 1	Homo sapiens	75-86
3036276-1	1987	Human fibrinogen has an Arg-Gly-Asp-Ser (RGDS) sequence at residues 572-575 of its A alpha-chain.	Glycine	28-31	fibrinogen beta chain	Homo sapiens	6-16
2956269-4	1987	The RGDS tetrapeptide (arg-gly-asp-ser) from the cell attachment domain of fibronectin can specifically block attachment and outgrowth on both fibronectin- and laminin-coated substrates.	Glycine	27-30	fibronectin 1	Homo sapiens	143-154
3584243-10	1987	Clustering was also induced by the addition of the GPIIb-IIIa-binding domains of fibrinogen, namely the tetrapeptide Arg-Gly-Asp-Ser on the alpha-chain or the gamma-chain decapeptide gamma 402-411.	Glycine	121-124	fibrinogen beta chain	Homo sapiens	81-91
3584243-10	1987	Clustering was also induced by the addition of the GPIIb-IIIa-binding domains of fibrinogen, namely the tetrapeptide Arg-Gly-Asp-Ser on the alpha-chain or the gamma-chain decapeptide gamma 402-411.	Glycine	121-124	Fc gamma receptor and transporter	Homo sapiens	140-151
3814824-1	1987	The alpha chain 572-574 Arg-Gly-Asp sequence of fibrinogen appears to play only a minor role in platelet aggregation based on the ability of fibrinogen preparations lacking alpha chain carboxyterminal segments to support platelet aggregation, but synthetic Arg-Gly-Asp-Ser (RGDS) peptides are capable of inhibiting platelet aggregation and fibrinogen binding.	Glycine	28-31	fibrinogen beta chain	Homo sapiens	48-58
3037722-0	1987	Inhibition of von Willebrand factor binding to platelets by two recognition site peptides: the pentadecapeptide of the carboxy terminus of the fibrinogen gamma chain and the tetrapeptide arg-gly-asp-ser.	Glycine	191-194	von Willebrand factor	Homo sapiens	14-35
3031217-4	1987	The release of the putative neurotransmitter AAs glutamate (Glu), taurine (Tau), and glycine (Gly) were similarly increased by 50-150% with m-ENK in slices of CS, but not Cx.	Glycine	85-92	proopiomelanocortin	Homo sapiens	140-145
3031217-4	1987	The release of the putative neurotransmitter AAs glutamate (Glu), taurine (Tau), and glycine (Gly) were similarly increased by 50-150% with m-ENK in slices of CS, but not Cx.	Glycine	94-97	proopiomelanocortin	Homo sapiens	140-145
3031217-9	1987	Nonetheless, m-ENK (10 microM) markedly increased the release of Tyr (to 833%), but not Glu, Gly, and Tau from the P2 fraction.	Glycine	93-96	proopiomelanocortin	Homo sapiens	13-18
3603730-4	1987	Thrombin is shown to split the most effectively tripeptide containing amino acids sequence Gly-Gly at the subsites of P3 and P2.	Glycine	91-94	coagulation factor II, thrombin	Homo sapiens	0-8
3603730-4	1987	Thrombin is shown to split the most effectively tripeptide containing amino acids sequence Gly-Gly at the subsites of P3 and P2.	Glycine	91-94	solute carrier family 10 member 3	Homo sapiens	118-127
3603730-4	1987	Thrombin is shown to split the most effectively tripeptide containing amino acids sequence Gly-Gly at the subsites of P3 and P2.	Glycine	95-98	coagulation factor II, thrombin	Homo sapiens	0-8
3603730-4	1987	Thrombin is shown to split the most effectively tripeptide containing amino acids sequence Gly-Gly at the subsites of P3 and P2.	Glycine	95-98	solute carrier family 10 member 3	Homo sapiens	118-127
2439116-0	1987	Assignment of asparagine-44 side-chain primary amide 1H NMR resonances and the peptide amide N1H resonance of glycine-37 in basic pancreatic trypsin inhibitor.	Glycine	110-117	trophoblast Kunitz domain protein 1	Bos taurus	141-158
3300695-1	1987	The S-thiomethyl derivatives of insulin A chain with A1-Gly replaced by D- or L-Trp have been prepared and their respective interaction and combination with the S-thiomethyl B chain studied.	Glycine	56-59	insulin	Homo sapiens	32-39
3814824-1	1987	The alpha chain 572-574 Arg-Gly-Asp sequence of fibrinogen appears to play only a minor role in platelet aggregation based on the ability of fibrinogen preparations lacking alpha chain carboxyterminal segments to support platelet aggregation, but synthetic Arg-Gly-Asp-Ser (RGDS) peptides are capable of inhibiting platelet aggregation and fibrinogen binding.	Glycine	261-264	fibrinogen beta chain	Homo sapiens	48-58
3545826-1	1987	A synthetic gene for bovine pancreatic ribonuclease A (RNase A) has been expressed in Escherichia coli as a fusion protein with beta-galactosidase linked by the tetrapeptide Ile-Glu-Gly-Arg.	Glycine	182-185	ribonuclease pancreatic	Bos taurus	39-53
3493352-3	1987	Mutant pA-1, which has a codon for valine substituted for that of the normally myristylated glycine, is completely noninfectious.	Glycine	92-99	PAXIP1 associated glutamate rich protein 1	Homo sapiens	7-11
3469204-2	1987	The peptide was designed to be triple helical and to contain the sequence Arg-Gly-Asp, which has been implicated as the cell attachment site of fibronectin, vitronectin, fibrinogen, and von Willebrand factor, and is also present in type I collagen.	Glycine	78-81	fibronectin 1	Homo sapiens	144-155
3469204-2	1987	The peptide was designed to be triple helical and to contain the sequence Arg-Gly-Asp, which has been implicated as the cell attachment site of fibronectin, vitronectin, fibrinogen, and von Willebrand factor, and is also present in type I collagen.	Glycine	78-81	fibrinogen beta chain	Homo sapiens	170-180
2434549-8	1987	The enhancing activities of TCS on IgE synthesis and on histamine release could be removed by absorption with IgE-Sepharose and subsequently recovered by elution with glycine buffer.	Glycine	167-174	immunoglobulin heavy constant epsilon	Homo sapiens	35-38
3545826-1	1987	A synthetic gene for bovine pancreatic ribonuclease A (RNase A) has been expressed in Escherichia coli as a fusion protein with beta-galactosidase linked by the tetrapeptide Ile-Glu-Gly-Arg.	Glycine	182-185	ribonuclease pancreatic	Bos taurus	55-62
3468508-5	1987	There are, however, significant differences at their amino and carboxyl termini and a substitution of an alanine in intestinal alkaline phosphatase for a glycine in the active site of the placental isozyme.	Glycine	154-161	alkaline phosphatase, intestinal	Homo sapiens	116-147
2955429-6	1987	By the use of glycine as spacer the compounds become tight binding thrombin inhibitors, while introduction of other omega-amino acids, Gly-Gly, L-Pro, Gly-L-Pro or L-Pro-Gly, reduces the specificity and potency of thrombin inhibition.	Glycine	14-21	coagulation factor II, thrombin	Homo sapiens	67-75
2434337-2	1987	A glycine to arginine substitution at HA1 135 abrogates recognition by a panel of T cell clones which, according to their reactivity for natural virus variants, have different antigenic specificities: three clones recognize a synthetic peptide (HA1 residues 118-138) but fail to recognize the monoclonal antibody-selected mutant (Gly135/Arg).	Glycine	2-9	Rho GTPase activating protein 45	Mus musculus	38-41
2948571-10	1987	Several other organic solutes (proline, 4-hydroxyproline, glycine, trimethylamine N-oxide, glycerol and myo-inositol) that afford cryoprotection to phosphofructokinase, an effect enhanced by the addition of zinc, do not stabilize the enzyme during freeze-drying, even if zinc is present.	Glycine	58-65	ATP-dependent 6-phosphofructokinase, muscle type	Oryctolagus cuniculus	148-167
2434337-2	1987	A glycine to arginine substitution at HA1 135 abrogates recognition by a panel of T cell clones which, according to their reactivity for natural virus variants, have different antigenic specificities: three clones recognize a synthetic peptide (HA1 residues 118-138) but fail to recognize the monoclonal antibody-selected mutant (Gly135/Arg).	Glycine	2-9	Rho GTPase activating protein 45	Mus musculus	245-248
3805128-6	1987	For inhibiting interactions with laminin or native type I collagen gels, Gly-Arg-Gly-Asp-Ser was only weakly active, but the inverted peptide Ser-Asp-Gly-Arg unexpectedly continued to display inhibitory activity for both attachment proteins in both cell types.	Glycine	73-76	laminin, beta 2 (laminin S)	Gallus gallus	33-40
2835765-11	1986	From predictions on the structure of these conserved blocks, we have proposed that the location of a substrate binding site within RR1 is centered on three conserved glycine residues in a region which is predicted to adopt a beta-sheet/turn/alpha-helical structure; this approximates to the structure for ADP nucleotide binding folds.	Glycine	166-173	amyloid beta precursor protein	Homo sapiens	223-229
3330776-3	1987	Although the amino acid sequence between Gly-78 and the carboxy-terminus of the c-fgr is highly homologous to the corresponding sequence of the c-yes protein, the homology between the two proteins is low in the amino-terminal proximal region.	Glycine	41-44	FGR proto-oncogene, Src family tyrosine kinase	Homo sapiens	80-85
3330776-3	1987	Although the amino acid sequence between Gly-78 and the carboxy-terminus of the c-fgr is highly homologous to the corresponding sequence of the c-yes protein, the homology between the two proteins is low in the amino-terminal proximal region.	Glycine	41-44	YES proto-oncogene 1, Src family tyrosine kinase	Homo sapiens	144-149
3111087-3	1987	Contaminating fibrinogen was precipitated by the addition of 2.8 M glycine buffer at 30 degrees C. The fibrinogen precipitate was removed by filtration using a layer of glass beads.	Glycine	67-74	fibrinogen beta chain	Homo sapiens	14-24
20501118-2	1987	As enkephalinase cleaved CCK-8 at the Gly(4)-Trp(5), Trp(5)-Met(6) and Asp(7)-Phe(8) bonds, we investigated the stability of analogues having: (1) substitutions of l amino acids by a d stereoisomer, (2) a substitution of Asp(7) by a ?	Glycine	38-41	cholecystokinin	Homo sapiens	25-28
3827867-8	1986	There exists a new form of autolysed thrombin, designated as beta"-thrombin (with cleavage at Lys-Gly only), which also serves as the intermediate in the conversion of alpha-thrombin into gamma-thrombin.	Glycine	98-101	coagulation factor II, thrombin	Homo sapiens	37-45
3827867-8	1986	There exists a new form of autolysed thrombin, designated as beta"-thrombin (with cleavage at Lys-Gly only), which also serves as the intermediate in the conversion of alpha-thrombin into gamma-thrombin.	Glycine	98-101	coagulation factor II, thrombin	Homo sapiens	67-75
3827867-8	1986	There exists a new form of autolysed thrombin, designated as beta"-thrombin (with cleavage at Lys-Gly only), which also serves as the intermediate in the conversion of alpha-thrombin into gamma-thrombin.	Glycine	98-101	coagulation factor II, thrombin	Homo sapiens	67-75
3827867-8	1986	There exists a new form of autolysed thrombin, designated as beta"-thrombin (with cleavage at Lys-Gly only), which also serves as the intermediate in the conversion of alpha-thrombin into gamma-thrombin.	Glycine	98-101	coagulation factor II, thrombin	Homo sapiens	67-75
2947871-1	1986	Vasopressin antagonist analogs having alanine or glycine at position 7 were essentially equipotent with analogs with proline, N-methylalanine or sarcosine at position 7.	Glycine	49-56	arginine vasopressin	Homo sapiens	0-11
3098173-0	1986	Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.	Glycine	17-24	myosin binding protein H like	Gallus gallus	114-123
3098173-0	1986	Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.	Glycine	74-81	myosin binding protein H like	Gallus gallus	114-123
3098173-0	1986	Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.	Glycine	74-81	myosin binding protein H like	Gallus gallus	114-123
3098173-1	1986	Glycine is converted to carbon dioxide and an intermediate attached to a lipoic acid group on H-protein in the P-protein-catalyzed partial reaction of the glycine cleavage reaction [K. Fujiwara and Y. Motokawa (1983) J. Biol.	Glycine	0-7	myosin binding protein H like	Gallus gallus	94-103
3098173-1	1986	Glycine is converted to carbon dioxide and an intermediate attached to a lipoic acid group on H-protein in the P-protein-catalyzed partial reaction of the glycine cleavage reaction [K. Fujiwara and Y. Motokawa (1983) J. Biol.	Glycine	155-162	myosin binding protein H like	Gallus gallus	94-103
3771519-7	1986	Thus, specific 125I-fibronectin binding was inhibited by excess unlabeled fibrinogen or fibronectin, the anti-GP IIb-IIIa monoclonal antibody 10E5, the decapeptide from the carboxyl terminus of the fibrinogen gamma-chain, and the tetrapeptide Arg-Gly-Asp-Ser from the cell-binding domain of fibronectin.	Glycine	247-250	fibronectin 1	Homo sapiens	20-31
2948553-1	1986	LexA repressor of Escherichia coli and phage lambda repressor are inactivated in vivo and in vitro by specific cleavage of an Ala-Gly peptide bond in reactions requiring RecA protein.	Glycine	130-133	DNA repair system	Escherichia coli	0-4
3018735-3	1986	The mitogenic fibrinogen receptor is not recognized by antibodies specific for the platelet fibrinogen receptor or is not competitively blocked by synthetic peptides containing the Arg-Gly-Asp sequence, which is common to fibronectin, fibrinogen, vitronectin, and other cell-attachment proteins.	Glycine	185-188	fibrinogen beta chain	Homo sapiens	14-24
2426110-6	1986	A beta-turn at residues Arg-18-Gly-19 may be present as a minor component.	Glycine	31-34	amyloid beta precursor protein	Homo sapiens	0-6
3099757-2	1986	The glycine N-terminus and the four tyrosine phenolic groups had the same properties as in the associated forms of insulin.	Glycine	4-11	insulin	Homo sapiens	115-122
3016716-10	1986	The peptide Tyr-His-His-Lys-Arg-Lys-Arg-Lys-Gln-Arg-Gly-Asp-Val was labeled with 125I to quantitate its binding to thrombin-stimulated platelets; at saturation, 59,990 molecules were bound per cell (Kd = 3.8 X 10(-7) M).	Glycine	52-55	coagulation factor II, thrombin	Homo sapiens	115-123
3019665-7	1986	Both the prosequence, composed of two D domains (D1, D2), and mature vWF harbor an arg-gly-asp ("R-G-D") sequence which has been implicated in cell-attachment functions.	Glycine	87-90	von Willebrand factor	Homo sapiens	69-72
3095629-7	1986	These observations were further confirmed by amino acid analysis of MTc which demonstrated high cysteine content (22.6) followed by serine, glycine and lysine.	Glycine	140-147	metallothionein 1A	Homo sapiens	68-71
3522581-0	1986	Chicken liver H-protein, a component of the glycine cleavage system.	Glycine	44-51	myosin binding protein H like	Gallus gallus	14-23
3755681-6	1986	Interesting features of the chromogranin A structure include repeated clusters of glutamic acid residues, the occurrence of eight potential dibasic cleavage sites, six of which are located in the C-terminal domain, and the presence, in the N-terminal domain, of -Arg-Gly-Asp- (RGD), a three amino acid sequence involved in the binding of several constitutively secreted proteins to cell membranes.	Glycine	267-270	chromogranin A	Bos taurus	28-42
3013204-3	1986	Lysyl bradykinin was cleaved similarly to release the same dipeptides plus the hexapeptide Lys-Arg-Pro-Pro-Gly-Phe.	Glycine	107-110	kininogen 1	Homo sapiens	6-16
3725588-5	1986	Computerized analysis of the kinetics of processing indicates that tRNA Asp, tRNA Gly, tRNA Glu and tRNA His transcripts are processed in a substrate concentration-dependent manner and also reveals the existence of a common rate-limiting step, the rate constant of which is equivalent for three of the four transcripts tested.	Glycine	82-85	mitochondrially encoded tRNA glycine	Homo sapiens	67-71
3725588-5	1986	Computerized analysis of the kinetics of processing indicates that tRNA Asp, tRNA Gly, tRNA Glu and tRNA His transcripts are processed in a substrate concentration-dependent manner and also reveals the existence of a common rate-limiting step, the rate constant of which is equivalent for three of the four transcripts tested.	Glycine	82-85	mitochondrially encoded tRNA glycine	Homo sapiens	77-81
3725588-5	1986	Computerized analysis of the kinetics of processing indicates that tRNA Asp, tRNA Gly, tRNA Glu and tRNA His transcripts are processed in a substrate concentration-dependent manner and also reveals the existence of a common rate-limiting step, the rate constant of which is equivalent for three of the four transcripts tested.	Glycine	82-85	mitochondrially encoded tRNA glycine	Homo sapiens	77-81
3725588-5	1986	Computerized analysis of the kinetics of processing indicates that tRNA Asp, tRNA Gly, tRNA Glu and tRNA His transcripts are processed in a substrate concentration-dependent manner and also reveals the existence of a common rate-limiting step, the rate constant of which is equivalent for three of the four transcripts tested.	Glycine	82-85	mitochondrially encoded tRNA glycine	Homo sapiens	77-81
3718539-4	1986	However, angiotensin converting enzyme degraded des-Arg9-bradykinin in plasma or serum prior to such Phe removal to yield the pentapeptide Arg-Pro-Pro-Gly-Phe and the tripeptide Ser-Pro-Phe.	Glycine	151-154	kininogen 1	Homo sapiens	57-67
2424500-1	1986	The peptide portion of the lipopeptide isolated from bovine myelin basic protein contained glycine, lysine, and serine in a 2:1:1 molar ratio as determined by amino acid analysis.	Glycine	91-98	myelin basic protein	Bos taurus	60-80
3524673-12	1986	The protein also contains the tetrapeptide sequence Arg-Gly-Asp-Ser (at residues 1744-1747), which may be a cell attachment site, as in fibronectin.	Glycine	56-59	fibronectin 1	Homo sapiens	136-147
2424500-3	1986	The tetrapeptide Gly53-Ser-Gly-Lys56 was the only segment of myelin basic protein that matched the above two characteristics.	Glycine	17-20	myelin basic protein	Bos taurus	61-81
2422209-5	1986	The structural basis for the cross-reactivity of the RA synovial membrane 62,000-mol-wt protein and the EBNA-1 antigen appears to reside in the glycine-alanine rich region of these molecules.	Glycine	144-151	EBNA-1	Human gammaherpesvirus 4	104-110
2420006-5	1986	This platelet receptor is related to the previously identified fibronectin and vitronectin receptors in that it recognizes an Arg-Gly-Asp sequence but differs from the other receptors in its wider specificity toward various adhesive proteins.	Glycine	130-133	fibronectin 1	Homo sapiens	63-74
2422209-6	1986	A rabbit antibody directed against a synthetic peptide (IR3-VI-2) derived from the glycine-alanine-rich region of EBNA-1 reacted with the 70,000-85,000-mol-wt EBNA-1 antigen in EBV-infected cells and with the 62,000-mol-wt molecule in RA synovial membrane extracts.	Glycine	83-90	EBNA-1	Human gammaherpesvirus 4	114-120
2422209-6	1986	A rabbit antibody directed against a synthetic peptide (IR3-VI-2) derived from the glycine-alanine-rich region of EBNA-1 reacted with the 70,000-85,000-mol-wt EBNA-1 antigen in EBV-infected cells and with the 62,000-mol-wt molecule in RA synovial membrane extracts.	Glycine	83-90	EBNA-1	Human gammaherpesvirus 4	159-165
3088605-8	1986	It is concluded that an elevated conversion of serine into glycine via serine hydroxymethyltransferase (SHMT) may be responsible for the enhanced NH biosynthesis.	Glycine	59-66	serine hydroxymethyltransferase 1	Rattus norvegicus	71-102
3088605-8	1986	It is concluded that an elevated conversion of serine into glycine via serine hydroxymethyltransferase (SHMT) may be responsible for the enhanced NH biosynthesis.	Glycine	59-66	serine hydroxymethyltransferase 1	Rattus norvegicus	104-108
2422658-2	1986	The interaction of these thymocytes with fibronectin could be inhibited by the synthetic peptide Gly-Arg-Gly-Asp-Ser-Pro, which comprises the previously identified cell-attachment determinant of the molecule, suggesting that the cell attachment site on fibronectin is recognized by these cells.	Glycine	97-100	fibronectin 1	Homo sapiens	41-52
2422658-2	1986	The interaction of these thymocytes with fibronectin could be inhibited by the synthetic peptide Gly-Arg-Gly-Asp-Ser-Pro, which comprises the previously identified cell-attachment determinant of the molecule, suggesting that the cell attachment site on fibronectin is recognized by these cells.	Glycine	97-100	fibronectin 1	Homo sapiens	253-264
2420006-2	1986	The binding of both of these proteins to platelets is inhibited by synthetic peptides containing the sequence Arg-Gly-Asp, which corresponds to the cell adhesion site in fibronectin and is also present in the alpha chain of fibrinogen.	Glycine	114-117	fibronectin 1	Homo sapiens	170-181
2420006-2	1986	The binding of both of these proteins to platelets is inhibited by synthetic peptides containing the sequence Arg-Gly-Asp, which corresponds to the cell adhesion site in fibronectin and is also present in the alpha chain of fibrinogen.	Glycine	114-117	fibrinogen beta chain	Homo sapiens	224-234
3754463-3	1986	A fragment of MLCK containing the phosphorylation site was shown to have the amino acid sequence Ala-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu- Ser-Ser.	Glycine	129-132	myosin light chain kinase, smooth muscle	Oryctolagus cuniculus	14-18
2423506-7	1986	The amino acid sequence from the amino terminus of the 42,000-dalton fragment is Asp/Gly-Gln/Val-?-Ile-Val-, which is almost identical to the sequence Asp-Gln-Cys-Ile-Val- located in the carboxyl terminal 1/3 of the collagen-binding domain of human fibronectin (Kornblihtt et al.	Glycine	85-88	fibronectin 1	Homo sapiens	249-260
2935541-4	1986	Both MEL cells and reticulocytes attached to the same site on fibronectin as do fibroblasts since adhesion of erythroid cells to fibronectin was specifically blocked by a monoclonal antibody directed against the cell-binding fragment of fibronectin and by a synthetic peptide containing the Arg-Gly-Asp-Ser sequence found in the cell-binding fragment of fibronectin.	Glycine	295-298	fibronectin 1	Homo sapiens	129-140
2935541-4	1986	Both MEL cells and reticulocytes attached to the same site on fibronectin as do fibroblasts since adhesion of erythroid cells to fibronectin was specifically blocked by a monoclonal antibody directed against the cell-binding fragment of fibronectin and by a synthetic peptide containing the Arg-Gly-Asp-Ser sequence found in the cell-binding fragment of fibronectin.	Glycine	295-298	fibronectin 1	Homo sapiens	129-140
2935541-4	1986	Both MEL cells and reticulocytes attached to the same site on fibronectin as do fibroblasts since adhesion of erythroid cells to fibronectin was specifically blocked by a monoclonal antibody directed against the cell-binding fragment of fibronectin and by a synthetic peptide containing the Arg-Gly-Asp-Ser sequence found in the cell-binding fragment of fibronectin.	Glycine	295-298	fibronectin 1	Homo sapiens	129-140
3511910-2	1986	Partial purification by glycine affinity chromatography separates enzyme from inhibitor to yield a preparation which hydrolyzes angiotensin-1, bradykinin, substance P, atriopeptin-2, enkephalin and Hip-His-Leu.	Glycine	24-31	tachykinin precursor 1	Bos taurus	155-166
3950530-0	1986	Effects of vasopressin-glycine and vasopressin-glycine-lysine-arginine on renal function in the rat.	Glycine	47-54	arginine vasopressin	Rattus norvegicus	35-46
3950530-1	1986	The peptides vasopressin-Gly and vasopressin-Gly-Lys-Arg occur as part of the sequence of the vasopressin-neurophysin precursor molecule and may be released from the hypothalamus and/or pituitary.	Glycine	25-28	arginine vasopressin	Rattus norvegicus	13-24
3950530-1	1986	The peptides vasopressin-Gly and vasopressin-Gly-Lys-Arg occur as part of the sequence of the vasopressin-neurophysin precursor molecule and may be released from the hypothalamus and/or pituitary.	Glycine	45-48	arginine vasopressin	Rattus norvegicus	33-44
3950530-1	1986	The peptides vasopressin-Gly and vasopressin-Gly-Lys-Arg occur as part of the sequence of the vasopressin-neurophysin precursor molecule and may be released from the hypothalamus and/or pituitary.	Glycine	45-48	arginine vasopressin	Rattus norvegicus	33-44
2417560-1	1985	Dimethylglycine dehydrogenase (EC 1.5.99.2) and sarcosine dehydrogenase (EC 1.5.99.1) are flavoproteins which catalyze the oxidative demethylation of dimethylglycine to sarcosine and sarcosine to glycine, respectively.	Glycine	8-15	sarcosine dehydrogenase	Rattus norvegicus	48-71
2871693-5	1986	Following the above mentioned N-terminal modification, the amino group of the C-terminal glycine was also substituted by methyl-esther (Gly-OMe), Z-D-Pip-Leu-Gly-OMe decreased the mesencephalic DA level, while Z-L-Pip-Leu-Gly-OMe increased the 5-HT content of the mesencephalon and striatum.	Glycine	89-96	prolactin induced protein	Rattus norvegicus	150-153
2871693-5	1986	Following the above mentioned N-terminal modification, the amino group of the C-terminal glycine was also substituted by methyl-esther (Gly-OMe), Z-D-Pip-Leu-Gly-OMe decreased the mesencephalic DA level, while Z-L-Pip-Leu-Gly-OMe increased the 5-HT content of the mesencephalon and striatum.	Glycine	89-96	prolactin induced protein	Rattus norvegicus	214-217
3755763-5	1986	However, a consensus organophosphate-binding hexapeptide sequence Phe-Gly-Glu-Ser-Ala-Gly was found both in "true" acetylcholinesterase from the electric organ of Torpedo [McPhee-Quigley et al: J Biol Chem 260:12185-12189, 1985] and in "pseudocholinesterase" (butyrylcholinesterase) from human serum [Lockridge: "Cholinesterases--Fundamental and Applied Aspects."	Glycine	70-73	acetylcholinesterase (Cartwright blood group)	Homo sapiens	115-135
20493060-0	1986	Immunohistochemical and biochemical evidence for the presence of the pentapeptide met-enkephalin and the heptapeptide met-enkephalin-Arg(6)-Phe(7) but not the octapeptide met-enkephalin-Arg(6)-Gly(7)-Leu(8) in amphibian chromaffin cells.	Glycine	193-196	proopiomelanocortin	Homo sapiens	82-96
20493060-0	1986	Immunohistochemical and biochemical evidence for the presence of the pentapeptide met-enkephalin and the heptapeptide met-enkephalin-Arg(6)-Phe(7) but not the octapeptide met-enkephalin-Arg(6)-Gly(7)-Leu(8) in amphibian chromaffin cells.	Glycine	193-196	proopiomelanocortin	Homo sapiens	118-132
20493060-0	1986	Immunohistochemical and biochemical evidence for the presence of the pentapeptide met-enkephalin and the heptapeptide met-enkephalin-Arg(6)-Phe(7) but not the octapeptide met-enkephalin-Arg(6)-Gly(7)-Leu(8) in amphibian chromaffin cells.	Glycine	193-196	proopiomelanocortin	Homo sapiens	118-132
3768476-4	1986	The T1 values of labelled glycine were also determined in various-concentration solutions of bovine serum albumin and glycerol and also of the natural abundance 13C of glycerol in glycerol solutions.	Glycine	26-33	albumin	Homo sapiens	100-113
3865207-4	1985	Calmodulin, which lacks the central glycine, also is predicted to be stabilized by salt bridges in the central helix.	Glycine	36-43	calmodulin 1	Homo sapiens	0-10
4083898-10	1985	The finding that cytochrome P-450 and the 55-kDa protein were selectively retained by the affinity column and eluted with NaCl (2 M) and glycine (0.2 M, pH 3.0) and that this fraction contained aromatase activity upon reconstitution with purified NADPH-cytochrome P-450 reductase and phospholipid, is indicative that the 55-kDa protein is indeed cytochrome P-450AROM.	Glycine	137-144	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	17-33
2866019-4	1985	In this report, we show that 3 neuroactive peptides (enkephalin, neurotensin and somatostatin) are present in subpopulations of amacrine cells which also possess a high affinity uptake system for glycine.	Glycine	196-203	neurotensin	Gallus gallus	65-76
3877935-1	1985	The Arg-Gly-Asp sequence resides in the cell attachment region of fibronectin.	Glycine	8-11	fibronectin 1	Homo sapiens	66-77
3877935-2	1985	Arg-Gly-Asp-containing peptides support fibroblast attachment, inhibit fibroblast adhesion to fibronectin, and inhibit fibronectin binding to thrombin-stimulated platelets.	Glycine	4-7	fibronectin 1	Homo sapiens	94-105
3877935-2	1985	Arg-Gly-Asp-containing peptides support fibroblast attachment, inhibit fibroblast adhesion to fibronectin, and inhibit fibronectin binding to thrombin-stimulated platelets.	Glycine	4-7	fibronectin 1	Homo sapiens	119-130
3877935-2	1985	Arg-Gly-Asp-containing peptides support fibroblast attachment, inhibit fibroblast adhesion to fibronectin, and inhibit fibronectin binding to thrombin-stimulated platelets.	Glycine	4-7	coagulation factor II, thrombin	Homo sapiens	142-150
2995350-4	1985	Moreover, the amino acid sequence Arg-Gly-Asp-Ser, corresponding to the cell attachment site of fibronectin, is located near the carboxyl-terminal region of the alpha-chain of fibrinogen.	Glycine	38-41	fibronectin 1	Homo sapiens	96-107
4055729-6	1985	The sequence determined for the flavin-peptide from sarcosine dehydrogenase contained 14 amino acid residues Leu-Thr-Ser-Gly-Thr-Thr-Trp-His(flavin)-Thr-Ala-Gly-Leu-Gly-Arg.	Glycine	121-124	sarcosine dehydrogenase	Rattus norvegicus	52-75
4055729-6	1985	The sequence determined for the flavin-peptide from sarcosine dehydrogenase contained 14 amino acid residues Leu-Thr-Ser-Gly-Thr-Thr-Trp-His(flavin)-Thr-Ala-Gly-Leu-Gly-Arg.	Glycine	157-160	sarcosine dehydrogenase	Rattus norvegicus	52-75
4055729-6	1985	The sequence determined for the flavin-peptide from sarcosine dehydrogenase contained 14 amino acid residues Leu-Thr-Ser-Gly-Thr-Thr-Trp-His(flavin)-Thr-Ala-Gly-Leu-Gly-Arg.	Glycine	157-160	sarcosine dehydrogenase	Rattus norvegicus	52-75
2995350-4	1985	Moreover, the amino acid sequence Arg-Gly-Asp-Ser, corresponding to the cell attachment site of fibronectin, is located near the carboxyl-terminal region of the alpha-chain of fibrinogen.	Glycine	38-41	fibrinogen beta chain	Homo sapiens	176-186
2411731-2	1985	Analysis of amino acids 796-1020 in the human alpha 2(V) Gly-X-Y region showed strong conservation of charged positions with the interstitial collagens but also revealed substitutions unique to type V. To gain more information about this procollagen and primarily to resolve the ambiguous nature of the 3" noncollagenous propeptide, we sequenced several cDNA clones coding for amino acids adjacent to the carboxyl end of the alpha chain.	Glycine	57-60	collagen type V alpha 2 chain	Homo sapiens	46-56
2866656-1	1985	The ability of certain neuropeptides (glucagon, somatostatin, leu-enkephalin and neurotensin) to release known neurotransmitters (glycine, GABA, dopamine and 5-hydroxytryptamine) was tested in the chicken retina.	Glycine	130-137	neurotensin	Gallus gallus	81-92
2864688-10	1985	The tetrapeptide sequence of Arg-Gly-Asp-Ser, which mediates the cell attachment and platelet binding activity of fibronectin, was also identified in the carboxyl-terminal portion of von Willebrand factor.	Glycine	33-36	fibronectin 1	Homo sapiens	114-125
2864688-10	1985	The tetrapeptide sequence of Arg-Gly-Asp-Ser, which mediates the cell attachment and platelet binding activity of fibronectin, was also identified in the carboxyl-terminal portion of von Willebrand factor.	Glycine	33-36	von Willebrand factor	Homo sapiens	183-204
3840230-9	1985	Each of these regions contains the presumed active site sequence Trp-Cys-Gly-His-Cys-Lys, suggesting that PDI, similar in action to thioredoxin, catalyses disulphide bond interchange via an internal disulphide-sulphydryl interchange.	Glycine	73-76	thioredoxin 1	Rattus norvegicus	132-143
3876125-2	1985	The prototypical peptide gly-arg-gly-asp-ser was capable of inhibiting thrombin-induced platelet aggregation without altering the degree of platelet activation as judged by the secretion of 14C-serotonin.	Glycine	25-28	coagulation factor II, thrombin	Homo sapiens	71-79
3876125-4	1985	The smallest peptide from the cell-binding region of fibronectin which retained full activity was arg-gly-asp-ser.	Glycine	102-105	fibronectin 1	Homo sapiens	53-64
3876125-6	1985	Peptides containing the arg-gly-asp-ser sequence were also capable of inhibiting the adhesion of platelets to fibrinogen and von Willebrand factor substrates.	Glycine	28-31	fibrinogen beta chain	Homo sapiens	110-120
2414098-7	1985	An Arg-Gly-Asp sequence, which has previously been shown to be the cell attachment site in fibronectin, was found in vitronectin immediately after the NH2-terminal somatomedin B sequence.	Glycine	7-10	fibronectin 1	Homo sapiens	91-102
2863141-7	1985	The optimum cleavage site for alpha-thrombin has the structures of (a) P4-P3-Pro-Arg-P1"-P2", where P3 and P4 are hydrophobic amino acid and P1", P2" are nonacidic amino acids and (b) P2-Arg-P1", where P2 or P1" are Gly.	Glycine	216-219	coagulation factor II, thrombin	Homo sapiens	36-44
3902102-0	1985	[A new structural analog of human insulin--glycine-B30-insulin].	Glycine	43-50	insulin	Homo sapiens	34-41
3902102-0	1985	[A new structural analog of human insulin--glycine-B30-insulin].	Glycine	43-50	insulin	Homo sapiens	55-62
3902102-1	1985	Enzymatic-chemical preparation of glycine-B30-insulin, a new structural analog of human insulin has been performed.	Glycine	34-41	insulin	Homo sapiens	46-53
3902102-1	1985	Enzymatic-chemical preparation of glycine-B30-insulin, a new structural analog of human insulin has been performed.	Glycine	34-41	insulin	Homo sapiens	88-95
2991265-8	1985	Both lung and brain ACE cleave Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 (substance P) via two pathways.	Glycine	63-67	angiotensin I converting enzyme	Rattus norvegicus	20-23
2412711-5	1985	From these results and data made up with the help of a computer comparison of known sequences of urokinase and a tissue-type plasminogen activator, we concluded that the epitope is Cys-Gln-Gly-Asp-Ser-Gly-Gly-Pro-Leu-Val-Cys and contains a catalytically active residue, serine.	Glycine	189-192	plasminogen activator, tissue type	Homo sapiens	113-146
2412711-5	1985	From these results and data made up with the help of a computer comparison of known sequences of urokinase and a tissue-type plasminogen activator, we concluded that the epitope is Cys-Gln-Gly-Asp-Ser-Gly-Gly-Pro-Leu-Val-Cys and contains a catalytically active residue, serine.	Glycine	189-193	plasminogen activator, tissue type	Homo sapiens	113-146
2412224-0	1985	A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.	Glycine	89-96	fibronectin 1	Homo sapiens	142-153
2412224-5	1985	In contrast, liposomes containing a previously identified 140-kDa fibronectin receptor, which interacts with the Arg-Gly-Asp sequence in fibronectin, did not bind to vitronectin.	Glycine	117-120	fibronectin 1	Homo sapiens	66-77
2412224-5	1985	In contrast, liposomes containing a previously identified 140-kDa fibronectin receptor, which interacts with the Arg-Gly-Asp sequence in fibronectin, did not bind to vitronectin.	Glycine	117-120	fibronectin 1	Homo sapiens	137-148
3839900-2	1985	A Chinese hamster ovary triple auxotroph (CHO AUXB1) requires glycine, adenosine, and thymidine (GAT) for growth and survival due to a defect in the structural gene for folylpolyglutamate synthetase (FPGS).	Glycine	62-69	folylpolyglutamate synthase, mitochondrial	Cricetulus griseus	169-198
2991265-13	1985	His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 (substance K) and bombesin are degraded by striatal but not lung ACE.	Glycine	28-31	angiotensin I converting enzyme	Rattus norvegicus	109-112
4027228-0	1985	Mechanism of action of thrombin on fibrinogen: NMR evidence for a beta-bend at or near fibrinogen A alpha Gly(P5)-Gly(P4).	Glycine	106-109	coagulation factor II, thrombin	Homo sapiens	23-31
2991128-4	1985	As the MPO-H2O2-Cl- system is capable of generating the powerful oxidant hypochlorous acid (HOCl), cytotoxicity assays were performed in the presence of taurine, glycine, serine and valine to scavenge this potentially lytic agent.	Glycine	162-169	myeloperoxidase	Homo sapiens	7-10
3886659-8	1985	In the course of screening a yeast DNA bank for initiator tRNA clones we have isolated and sequenced three yeast tRNA genes corresponding to glycine, alanine, and aspartic acid tRNAs.	Glycine	141-148	mitochondrially encoded tRNA glycine	Homo sapiens	58-62
3886659-8	1985	In the course of screening a yeast DNA bank for initiator tRNA clones we have isolated and sequenced three yeast tRNA genes corresponding to glycine, alanine, and aspartic acid tRNAs.	Glycine	141-148	mitochondrially encoded tRNA glycine	Homo sapiens	113-117
3886659-9	1985	The sequence of glycine tRNA gene differs from the published tRNA sequence in having an additional nucleotide in the variable loop.	Glycine	16-23	mitochondrially encoded tRNA glycine	Homo sapiens	24-28
4018266-5	1985	The N-terminal of native CoA synthase is proline, and proteolysis exposes glycine as a second N-terminal.	Glycine	74-81	Coenzyme A synthase	Sus scrofa	25-37
3160809-0	1985	Fibronectin receptor of human macrophages recognizes the sequence Arg-Gly-Asp-Ser.	Glycine	70-73	fibronectin 1	Homo sapiens	0-11
2991884-0	1985	Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.	Glycine	25-32	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	36-42
2991884-5	1985	Replacement of the NH2-terminal glycine in p60src with either alanine or glutamic acid prevented myristoylation completely.	Glycine	32-39	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	43-49
16664240-5	1985	Under low oxygen (1.8%), or in the presence of alpha-hydroxy-2-pyridine methanesulfonic acid (an inhibitor of glycolate oxidase, a step in the photorespiratory formation of glyoxylate), there was a substantial (60-80%) decrease in transfer of label to glycine, serine, ammonia, and glutamine.	Glycine	252-259	hydroxyacid oxidase 2	Homo sapiens	110-127
4027228-0	1985	Mechanism of action of thrombin on fibrinogen: NMR evidence for a beta-bend at or near fibrinogen A alpha Gly(P5)-Gly(P4).	Glycine	114-117	coagulation factor II, thrombin	Homo sapiens	23-31
24306655-10	1985	However, cruciferin contains a 38 amino acid region high in glutamine and glycine in the middle of the alpha subunit, which is absent in legumin.	Glycine	74-81	cruciferin	Brassica napus	9-19
2985590-4	1985	Our results and the results from the literature search suggest that the aminopeptidase cleaves amino-terminal methionine when it precedes residues of alanine, glycine, proline, serine, threonine, and valine but not when it precedes residues of arginine, asparagine, aspartic acid, glutamine glutamic acid, isoleucine, leucine, lysine, or methionine.	Glycine	159-166	aminopeptidase	Saccharomyces cerevisiae S288C	72-86
2408886-5	1985	These p15-related sequences contain a highly conserved stretch of amino acids which show a close similarity with sequences around the active site amino acids Asp-Thr-Gly of the acid protease family, suggesting that they have an activity similar to acid protease.	Glycine	166-169	cyclin dependent kinase inhibitor 2B	Homo sapiens	6-9
3886659-9	1985	The sequence of glycine tRNA gene differs from the published tRNA sequence in having an additional nucleotide in the variable loop.	Glycine	16-23	mitochondrially encoded tRNA glycine	Homo sapiens	61-65
3980461-5	1985	Of the smaller peptides studied from this sequence, all peptides containing the Arg-Gly-Asp-Ser sequence, including the tetrapeptide itself, were active in inhibiting Fn binding to platelets (ID50 values approximately 10-20 microM).	Glycine	84-87	fibronectin 1	Homo sapiens	167-169
3980461-10	1985	These data suggest that the Arg-Gly-Asp-Ser tetrapeptide contains a recognition specificity involved in the binding of Fn to platelets and that platelets share features of this recognition specificity with fibroblasts.	Glycine	32-35	fibronectin 1	Homo sapiens	119-121
3890831-0	1985	A general framework of cysteine-proteinase mechanism deduced from studies on enzymes with structurally different analogous catalytic-site residues Asp-158 and -161 (papain and actinidin), Gly-196 (cathepsin B) and Asn-165 (cathepsin H).	Glycine	188-191	cathepsin B	Bos taurus	197-208
3980461-9	1985	In addition, Arg-Gly-Asp-Ser-containing peptides inhibited the rate and extent of thrombin-induced platelet aggregation.	Glycine	17-20	coagulation factor II, thrombin	Homo sapiens	82-90
2936500-0	1985	[Hb J Camaguey [alpha 141 (HC3) Arg-Gly]--the first case identified in China].	Glycine	36-39	CYCS pseudogene 24	Homo sapiens	27-30
3920530-2	1985	Myristic acid is bound in an amide linkage to glycine 2 of p60src.	Glycine	46-53	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	59-65
2988200-4	1985	Output of protons into the medium and its acidification (alteration of pM by 0.01-0.012) within 3-6 sec was found in experiments with impulse administration of insulin 100 micrograms and pFCCP 0.1 micrograms into the suspension of freshly isolated rat adipocytes (5 ml) added to an electrolyte containing 150 mM NaCl, 10 mM beta-hydroxybutyric acid, 0.01 mM Gly-Gly (pH 7.45).	Glycine	358-361	insulin	Homo sapiens	160-167
2986058-3	1985	The results indicate an initial endopeptidase cleavage at the Met-Gly bond producing CCK-5 (Gly-Trp-Met-Asp-Phe-NH2).	Glycine	66-69	cholecystokinin	Homo sapiens	85-88
2988200-4	1985	Output of protons into the medium and its acidification (alteration of pM by 0.01-0.012) within 3-6 sec was found in experiments with impulse administration of insulin 100 micrograms and pFCCP 0.1 micrograms into the suspension of freshly isolated rat adipocytes (5 ml) added to an electrolyte containing 150 mM NaCl, 10 mM beta-hydroxybutyric acid, 0.01 mM Gly-Gly (pH 7.45).	Glycine	362-365	insulin	Homo sapiens	160-167
2983326-5	1985	ACE also released the COOH-terminal tripeptide, Arg-Pro-Gly-NH2, and then sequentially the dipeptides Gly-Leu and Ser-Try, leaving less than Glu-His-Trp intact.	Glycine	56-59	angiotensin I converting enzyme	Homo sapiens	0-3
6490722-3	1984	Fibroblast adhesion to fibronectin is competitively inhibited by certain synthetic peptides, including the decapeptide Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro, which appears to contain the cell recognition sequence.	Glycine	123-126	fibronectin 1	Homo sapiens	23-34
16453577-4	1984	The presence in the kidney bean genome of four leghemoglobin genes suggests that tandem duplications of a single primordial plant globin gene had occurred to generate four leghemoglobin genes in an ;Lb-locus" before Glycine and Phaseolus species diverged.	Glycine	216-223	leghemoglobin A	Glycine max	47-60
6085068-5	1984	By testing the immunogenicity of fragments of the 46-61 peptide, mouse lysozyme, and human lysozyme, we were able to localize the T cell determinant to either of two residues, Gly-49 or Leu-56.	Glycine	176-179	lysozyme	Homo sapiens	91-99
2981722-4	1985	N-terminal sequence analysis of peptide CP2bRA4SP9 established that C1r activation involves the cleavage of a single Arg-Ile bond, located in the sequence: ... Gln-Arg-Gln-Arg-Ile-Ile-Gly-Gly ... .	Glycine	184-187	complement C1r	Homo sapiens	68-71
3981164-4	1985	The spectroscopic data and pK values of the Gly-Trp deprotonatable groups (in the presence of the metal) suggest that the complexes are CuL2(pH approximately 5.0), CuL(H2O).	Glycine	44-47	cullin 2	Homo sapiens	136-140
6490627-10	1984	Amino acid composition and N-terminal analysis suggested the sequence of the flavin-peptide of sarcosine dehydrogenase was His(flavin)-(Ala, Gly,Thr)-Leu.	Glycine	141-144	sarcosine dehydrogenase	Rattus norvegicus	95-118
6099565-3	1984	Purification and sequencing of the larger molecular form reveals that it is a 22 amino acid C-terminal CCK fragment identical with pig CCK22 except that glycine instead of serine is present at the nineteenth residue from the C-terminus.	Glycine	153-160	cholecystokinin	Sus scrofa	103-106
6237366-1	1984	A tetrapeptide sequence, Arg-Gly-Asp-Ser, is the minimal structure recognized by cells in the large, adhesive glycoprotein fibronectin.	Glycine	29-32	fibronectin 1	Homo sapiens	123-134
6495993-2	1984	Met-enkephalin-Arg-Gly-Leu-like immunoreactivity (-LI) and Met-enkephalin-Arg-Phe-LI existed together with Met-enkephalin-LI and Leu-enkephalin-LI in 16 phaeochromocytomas.	Glycine	19-22	proopiomelanocortin	Homo sapiens	0-14
6495993-7	1984	These results indicate the co-existence of Met-enkephalin, Leu-enkephalin, Met-enkephalin-Arg-Gly-Leu and Met-enkephalin-Arg-Phe in human phaeochromocytomas, suggesting the preservation of amino acid sequences of these four opioid peptides even in neoplastic tissues.	Glycine	94-97	proopiomelanocortin	Homo sapiens	75-89
6495993-7	1984	These results indicate the co-existence of Met-enkephalin, Leu-enkephalin, Met-enkephalin-Arg-Gly-Leu and Met-enkephalin-Arg-Phe in human phaeochromocytomas, suggesting the preservation of amino acid sequences of these four opioid peptides even in neoplastic tissues.	Glycine	94-97	proopiomelanocortin	Homo sapiens	75-89
6390183-2	1984	We have isolated all possible base substitution mutations at the position 4 (N) in the 3"-CCCN-5" anticodon of a Saccharomyces cerevisiae frameshift suppressor glycine tRNA encoded by the SUF16 gene.	Glycine	160-167	SUF16	Saccharomyces cerevisiae S288C	188-193
6237366-5	1984	Assay of peptides containing the structure Arg-Gly-Asp-X (where X = another amino acid residue) showed that an Arg-Gly-Asp-Val sequence predicted to be present in some, but not all, fibronectin molecules as a result of alternative RNA splicings could potentially create a second cell attachment site in those fibronectin polypeptide chains carrying that sequence.	Glycine	47-50	fibronectin 1	Homo sapiens	182-193
6496678-4	1984	The high-Km system was inhibited primarily by neutral amino acids with small or polar side chains (alanine, serine, threonine, and glycine), resembling the ASC system in its specificity.	Glycine	131-138	PYD and CARD domain containing	Homo sapiens	156-159
6152637-3	1984	When tested against responses of Purkinje cell to depressant putative neurotransmitters, namely, GABA, glycine, taurine, 5-hydroxytryptamine and noradrenaline, it was observed that AII specifically enhanced depressant action of GABA, while the responses to other substances were unaffected.	Glycine	103-110	angiotensinogen	Rattus norvegicus	181-184
6237366-5	1984	Assay of peptides containing the structure Arg-Gly-Asp-X (where X = another amino acid residue) showed that an Arg-Gly-Asp-Val sequence predicted to be present in some, but not all, fibronectin molecules as a result of alternative RNA splicings could potentially create a second cell attachment site in those fibronectin polypeptide chains carrying that sequence.	Glycine	47-50	fibronectin 1	Homo sapiens	309-320
6745274-1	1984	The dithionite ion is catalytically disproportionated by lactoperoxidase with Km = 0.36 mM in 100 mM glycine HCl pH 3.0.	Glycine	101-112	lactoperoxidase	Homo sapiens	57-72
6237366-5	1984	Assay of peptides containing the structure Arg-Gly-Asp-X (where X = another amino acid residue) showed that an Arg-Gly-Asp-Val sequence predicted to be present in some, but not all, fibronectin molecules as a result of alternative RNA splicings could potentially create a second cell attachment site in those fibronectin polypeptide chains carrying that sequence.	Glycine	115-118	fibronectin 1	Homo sapiens	182-193
6237366-5	1984	Assay of peptides containing the structure Arg-Gly-Asp-X (where X = another amino acid residue) showed that an Arg-Gly-Asp-Val sequence predicted to be present in some, but not all, fibronectin molecules as a result of alternative RNA splicings could potentially create a second cell attachment site in those fibronectin polypeptide chains carrying that sequence.	Glycine	115-118	fibronectin 1	Homo sapiens	309-320
6237366-8	1984	The result presented here show that the arginine, glycine, and aspartic acid residues are absolutely required for the cell recognition, and that the surrounding amino acids may play a role in the expression of cell attachment activity in fibronectin and other proteins having this sequence.	Glycine	50-57	fibronectin 1	Homo sapiens	238-249
6238619-8	1984	(1980) Biochemistry 19, 2343] that the A alpha and B beta chains behave independently in their competition for thrombin; i.e., the hydrolyzable Arg-Gly bonds of the A alpha and B beta chains are both accessible to thrombin.	Glycine	148-151	coagulation factor II, thrombin	Homo sapiens	111-119
6435279-3	1984	By addition of glycine buffer to a final concentration of 2.0 M at 26 degrees C, the bulk of fibrinogen was precipitated while factor VIII remained in solution.	Glycine	15-22	fibrinogen beta chain	Homo sapiens	93-103
6146608-7	1984	Evidence is provided that serine in place of glycine at one or more positions causes a significant increase in specificity with factor XIIIa, but not with liver enzyme.	Glycine	45-52	coagulation factor XIII A chain	Homo sapiens	128-140
6088513-5	1984	Deamidation of asparagine 25 leads to the formation of an atypical isopeptide bond in which the resulting aspartyl residue is linked to the adjacent glycine 26 via its side-chain beta-carboxyl group rather than the usual alpha-carboxyl linkage (Graf, L., Bajusz, S., Patthy A., Barat, E., and Cseh, G. (1971) Acta Biochim.	Glycine	149-156	Rho GTPase activating protein 26	Homo sapiens	245-249
6427779-5	1984	The full sequence of chicken GnRH-II has been determined to be: pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2.	Glycine	85-88	mitochondrial ribosomal protein S26	Gallus gallus	29-36
6427779-5	1984	The full sequence of chicken GnRH-II has been determined to be: pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2.	Glycine	101-104	mitochondrial ribosomal protein S26	Gallus gallus	29-36
6472485-1	1984	The anticonvulsant effect of inhibitors of GABA-T (R/S-gamma-vinyl-GABA, ethanolamine-O-sulfate, gabaculine, aminooxyacetic acid) was enhanced by 10 mmol/kg glycine in animal seizure models which are based on a functional GABA deficit.	Glycine	157-164	4-aminobutyrate aminotransferase	Homo sapiens	43-49
6472485-5	1984	Combined treatment with GABA-T inhibitors and glycine may turn out to be of practical importance in the therapy of seizure disorders and other diseases, for which treatment with GABA-T inhibitors is considered a potentially useful therapeutic approach.	Glycine	46-53	4-aminobutyrate aminotransferase	Homo sapiens	178-184
6546517-2	1984	The sequence of the peptide is: GLY-GLY-GLU-VAL-LEU-GLY-LYS-ARG-TYR-GLY-GLY-PHE-MET (preproenkephalin 128-140) which represents a portion of peptide F (preproenkephalin 107-140).	Glycine	32-35	proenkephalin	Homo sapiens	85-101
6321602-8	1984	A unique sequence Gly-Gly-Lys-Gly-Glu-Lys identified this fragment as alpha 2(I) collagen.	Glycine	18-21	collagen type I alpha 2 chain	Homo sapiens	70-89
6321602-8	1984	A unique sequence Gly-Gly-Lys-Gly-Glu-Lys identified this fragment as alpha 2(I) collagen.	Glycine	22-25	collagen type I alpha 2 chain	Homo sapiens	70-89
6321602-8	1984	A unique sequence Gly-Gly-Lys-Gly-Glu-Lys identified this fragment as alpha 2(I) collagen.	Glycine	22-25	collagen type I alpha 2 chain	Homo sapiens	70-89
6696746-2	1984	The amino acid composition of this new species of tropoelastin is elastin-like in its high proportion of proline, glycine, alanine and valine.	Glycine	114-121	elastin	Gallus gallus	50-62
6546517-2	1984	The sequence of the peptide is: GLY-GLY-GLU-VAL-LEU-GLY-LYS-ARG-TYR-GLY-GLY-PHE-MET (preproenkephalin 128-140) which represents a portion of peptide F (preproenkephalin 107-140).	Glycine	32-35	proenkephalin	Homo sapiens	152-168
6546517-2	1984	The sequence of the peptide is: GLY-GLY-GLU-VAL-LEU-GLY-LYS-ARG-TYR-GLY-GLY-PHE-MET (preproenkephalin 128-140) which represents a portion of peptide F (preproenkephalin 107-140).	Glycine	36-39	proenkephalin	Homo sapiens	85-101
6546517-2	1984	The sequence of the peptide is: GLY-GLY-GLU-VAL-LEU-GLY-LYS-ARG-TYR-GLY-GLY-PHE-MET (preproenkephalin 128-140) which represents a portion of peptide F (preproenkephalin 107-140).	Glycine	36-39	proenkephalin	Homo sapiens	152-168
6546517-2	1984	The sequence of the peptide is: GLY-GLY-GLU-VAL-LEU-GLY-LYS-ARG-TYR-GLY-GLY-PHE-MET (preproenkephalin 128-140) which represents a portion of peptide F (preproenkephalin 107-140).	Glycine	36-39	proenkephalin	Homo sapiens	85-101
6546517-2	1984	The sequence of the peptide is: GLY-GLY-GLU-VAL-LEU-GLY-LYS-ARG-TYR-GLY-GLY-PHE-MET (preproenkephalin 128-140) which represents a portion of peptide F (preproenkephalin 107-140).	Glycine	36-39	proenkephalin	Homo sapiens	152-168
6352402-0	1983	Effects of insulin and glucagon on the incorporation of [14C]glycine into the protein of the liver and opercular muscle of the eel in vitro.	Glycine	56-68	insulin	Homo sapiens	11-18
6524712-6	1984	By homology with the sequence of human serum transferrin (MacGillivray et al., 1982) the Lys:Arg and Asp:Gly substitutions probably occur at residues 527 and 446, respectively, from the N-terminus.	Glycine	105-108	transferrin	Homo sapiens	45-56
16593407-5	1984	The tRNA(Gly) and tRNA(Arg) deduced from the DNA sequences show 84% and 55% sequence homologies with Escherichia coli tRNA(Gly) (UCC) and phage T4 tRNA(Arg) (UCU), respectively.	Glycine	123-126	T4t004	Escherichia phage T4	18-22
6412758-5	1983	In a reaction with lipoxygenase-1, anti-lipoxygenase-1 IgG, which was eluted with glycine-HCl buffer (pH 2.5) with recovery of 24%, had a 6.5-times higher affinity than the whole IgG fraction of antiserum.	Glycine	82-93	seed linoleate 13S-lipoxygenase-1	Glycine max	19-58
6626500-3	1983	The Michaelis-Menten parameters for the hydrolysis of the Arg-Gly bond in F-8 by thrombin were determined to be Kcat = 31 X 10(-11) M [(NIH unit/L) s]-1 and KM = 310 X 10(-6) M. Comparison of these values with those determined previously for native fibrinogen and for a series of similar synthetic peptides, together with information about the amino acid sequences of this portion of the A alpha chain of abnormal fibrinogens, suggests an important role for Asp at position P10.	Glycine	62-65	coagulation factor II, thrombin	Homo sapiens	81-89
6626500-3	1983	The Michaelis-Menten parameters for the hydrolysis of the Arg-Gly bond in F-8 by thrombin were determined to be Kcat = 31 X 10(-11) M [(NIH unit/L) s]-1 and KM = 310 X 10(-6) M. Comparison of these values with those determined previously for native fibrinogen and for a series of similar synthetic peptides, together with information about the amino acid sequences of this portion of the A alpha chain of abnormal fibrinogens, suggests an important role for Asp at position P10.	Glycine	62-65	fibrinogen beta chain	Homo sapiens	249-259
6626500-3	1983	The Michaelis-Menten parameters for the hydrolysis of the Arg-Gly bond in F-8 by thrombin were determined to be Kcat = 31 X 10(-11) M [(NIH unit/L) s]-1 and KM = 310 X 10(-6) M. Comparison of these values with those determined previously for native fibrinogen and for a series of similar synthetic peptides, together with information about the amino acid sequences of this portion of the A alpha chain of abnormal fibrinogens, suggests an important role for Asp at position P10.	Glycine	62-65	S100 calcium binding protein A10	Homo sapiens	474-477
6541489-2	1984	We show in the present report that the anticonvulsant effect of vinyl GABA, a GABA-T (4-aminobutyrate: 2-oxoglutarate aminotransferase) inhibitor with antiepileptic efficacy, can be amplified by esters of glycine.	Glycine	205-212	4-aminobutyrate aminotransferase	Homo sapiens	78-84
6316328-8	1983	In the first and the third domains, there is a common sequence of nine residues, Glu (or Asp)-Asn-Asn-Thr-Ile-Ser-Ser-Val-Lys, which is highly homologous to one of the proposed Ca2+-binding sequences in bovine brain calmodulin, Asp-Gly-Asn-Gly-Thr-Ile-Thr-Thr-Lys.	Glycine	232-235	calmodulin	Bos taurus	216-226
6316328-8	1983	In the first and the third domains, there is a common sequence of nine residues, Glu (or Asp)-Asn-Asn-Thr-Ile-Ser-Ser-Val-Lys, which is highly homologous to one of the proposed Ca2+-binding sequences in bovine brain calmodulin, Asp-Gly-Asn-Gly-Thr-Ile-Thr-Thr-Lys.	Glycine	240-243	calmodulin	Bos taurus	216-226
6352402-3	1983	Insulin also increased the incorporation of [14C]glycine into the liver protein, while a decrease in the radioactivity of the TCA-soluble fraction was observed.	Glycine	44-56	insulin	Homo sapiens	0-7
6623463-1	1983	We investigated levels of the glycine cleavage system in livers of spf-fur mutant mice with ornithine transcarbamylase (OTC) deficiency treated with sodium benzoate.	Glycine	30-37	ornithine transcarbamylase	Mus musculus	92-118
6870251-2	1983	Bovine serum albumin and lysozyme were preferentially hydrated in all of the amino acids examined, glycine, alpha- and beta-alanine, and betaine, i.e., addition of these amino acids resulted in an unfavorable free energy change.	Glycine	99-106	lysozyme	Homo sapiens	25-33
6863283-3	1983	In the partial reaction, glycine and H-protein serve as substrates and the products are CO2 (not bicarbonate) and the decarboxylated portion of glycine attached to H-protein.	Glycine	25-32	myosin binding protein H like	Gallus gallus	164-173
6863283-3	1983	In the partial reaction, glycine and H-protein serve as substrates and the products are CO2 (not bicarbonate) and the decarboxylated portion of glycine attached to H-protein.	Glycine	144-151	myosin binding protein H like	Gallus gallus	37-46
6863283-3	1983	In the partial reaction, glycine and H-protein serve as substrates and the products are CO2 (not bicarbonate) and the decarboxylated portion of glycine attached to H-protein.	Glycine	144-151	myosin binding protein H like	Gallus gallus	164-173
6863283-6	1983	Km values for glycine and H-protein are independent of the concentration of the the co-substrate, and calculated values are 5.8 mM for glycine and 3.4 microM for H-protein.	Glycine	14-21	myosin binding protein H like	Gallus gallus	162-171
6863283-6	1983	Km values for glycine and H-protein are independent of the concentration of the the co-substrate, and calculated values are 5.8 mM for glycine and 3.4 microM for H-protein.	Glycine	135-142	myosin binding protein H like	Gallus gallus	26-35
6863283-10	1983	H-protein whose lipoic acid prosthetic group and cysteinyl residues were modified with N-ethylmaleimide was a noncompetitive inhibitor of glycine and a competitive inhibitor of H-protein.	Glycine	138-145	myosin binding protein H like	Gallus gallus	0-9
6343062-4	1983	The first 24 residues beginning at the amino terminal glycine were identical to the corresponding residues in IGF-I.	Glycine	54-61	insulin like growth factor 1	Homo sapiens	110-115
6101263-1	1983	The protein kinase associated with the purified epidermal growth factor (EGF) receptor from membrane (Mr = 150,000) or vesicle (Mr = 170,000) preparations of A-431 cells was shown to catalyze the phosphorylation of the peptide Leu-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Arg-Arg-Gly at the tyrosine residue.	Glycine	271-274	epidermal growth factor receptor	Homo sapiens	48-86
6133871-8	1983	Partial microsequencing data indicates that the cleavage occurs between the glycine and alanine at positions 24 and 25 of pre-prosomatostatin.	Glycine	76-83	somatostatin	Canis lupus familiaris	126-141
6305005-5	1983	Protein P3-4a originates by cleavage of the RNA polymerase precursor at a glutamine-glycine amino acid pair not previously reported to be a viral cleavage site.	Glycine	84-102	solute carrier family 10 member 3	Homo sapiens	0-10
6857231-3	1983	N-terminal amino acid residues of Gp1 are glycine and alanine, and that of Gp2 is glycine.	Glycine	82-89	glycoprotein 2	Homo sapiens	75-78
6300077-5	1983	The attempts to remove endogenous transferrin from the extract by washing with agents such as 2.0 M KSCN and glycine/NaOH, pH 10.0, with 1 M NaCl or by immunoabsorption with anti-transferrin were unsuccessful in that substantial amounts (10%) of endogenous ligand remained.	Glycine	109-116	transferrin	Homo sapiens	34-45
6830821-3	1983	Two forms of activated colipase (N-terminal Gly) were isolated from human pancreatic juice by the same procedure.	Glycine	44-47	colipase	Homo sapiens	23-31
6830853-1	1983	A membrane-bound aminopeptidase which cleaves the tyrosine-glycine bond of enkephalin was purified about 1600-fold from monkey brain.	Glycine	59-66	carboxypeptidase Q	Homo sapiens	17-31
6857602-2	1983	The use of glycine as spacer renders the compounds tight binding inhibitors of thrombin.	Glycine	11-18	coagulation factor II, thrombin	Homo sapiens	79-87
6834030-8	1983	CuL2, the major species at neutral pH, exists in solution as an equilibrium mixture of a mixed-type chelation structure, with a glycine-like and a histamine-like bound histidine ligand, and a structure containing both histidine ligands bound histamine-like.	Glycine	128-135	cullin 2	Homo sapiens	0-4
6339497-4	1983	Both B29-lysine- and A1-glycine-substituted N-(2-nitro-4-azidophenyl)glycyl insulin compete with 125I-insulin for binding to 3T3-L1 adipocytes, and the B29-derivative retains a biological activity similar to that for native insulin.	Glycine	24-31	insulin	Homo sapiens	76-83
6339497-4	1983	Both B29-lysine- and A1-glycine-substituted N-(2-nitro-4-azidophenyl)glycyl insulin compete with 125I-insulin for binding to 3T3-L1 adipocytes, and the B29-derivative retains a biological activity similar to that for native insulin.	Glycine	24-31	insulin	Homo sapiens	102-109
6339497-4	1983	Both B29-lysine- and A1-glycine-substituted N-(2-nitro-4-azidophenyl)glycyl insulin compete with 125I-insulin for binding to 3T3-L1 adipocytes, and the B29-derivative retains a biological activity similar to that for native insulin.	Glycine	24-31	insulin	Homo sapiens	102-109
6687626-7	1983	As is the case for the bovine arginine-vasopressin-neurophysin II (AVP-NpII) precursor, the signal sequence of the OT-NpI precursor is immediately followed by the nonapeptide hormone which is connected to neurophysin I by a Gly-Lys-Arg sequence.	Glycine	224-227	oxytocin/neurophysin I prepropeptide	Bos taurus	115-121
6865038-0	1983	[Determination of fibrinogen subfractions by glycine method and SDS disc electrophoresis].	Glycine	45-52	fibrinogen beta chain	Homo sapiens	18-28
6679320-3	1983	Further studies on the glycine-14CO2 exchange catalyzed by p-protein and H-protein purified from chicken liver indicated that tiglyl CoA inhibited the activity of P-protein in an apparently competitive manner with respect to H-protein, and that cysteamine inhibited the activity of P-protein in two ways, by increasing the Km value for glycine and changing Vmax.	Glycine	23-30	myosin binding protein H like	Gallus gallus	73-82
6340098-4	1983	The amino acid sequence of the first 16-residue segment of Rauscher p15 is identical to the sequence of Moloney p15 except for a single amino acid substitution (Gly-->Asp) at position 13.	Glycine	161-164	cyclin dependent kinase inhibitor 2B	Mus musculus	68-71
6356166-5	1983	Proline and glycine residues suggest largely similar conformations between N-terminal parts of sorbitol dehydrogenase and "long" alcohol dehydrogenases, cysteine and histidine residues suggest a conserved zinc atom at the active site, and other residues correlate with structures of special importance.	Glycine	12-19	sorbitol dehydrogenase	Homo sapiens	95-117
6144310-1	1983	Cysteine and glycine for glutathione biosynthesis in human red cells enter via specific amino acid transport systems, principally system ASC and gly respectively.	Glycine	13-20	PYD and CARD domain containing	Homo sapiens	137-140
6144310-1	1983	Cysteine and glycine for glutathione biosynthesis in human red cells enter via specific amino acid transport systems, principally system ASC and gly respectively.	Glycine	13-16	PYD and CARD domain containing	Homo sapiens	137-140
7150549-3	1982	The rates of hydrolysis of the Arg-Gly bond in these peptides by thrombin were measured, and the rate for the Phe-containing peptide F-6 was found to be much larger than that for F-7.	Glycine	35-38	coagulation factor II, thrombin	Homo sapiens	65-73
7154837-3	1982	Purified brain angiotensin converting enzyme (EC 3.4.15.1) also converts E7 but a purified metalloendopeptidase acts on both E5 and E7 at the Gly-Phe site.	Glycine	142-145	angiotensin I converting enzyme	Rattus norvegicus	15-44
6749882-2	1982	We have synthesized the 12 amino acid C-peptide region of IGF-I (Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Glu-Thr) and developed a RIA based on antibodies against this synthetic peptide.	Glycine	65-68	insulin like growth factor 1	Homo sapiens	58-63
6749882-2	1982	We have synthesized the 12 amino acid C-peptide region of IGF-I (Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Glu-Thr) and developed a RIA based on antibodies against this synthetic peptide.	Glycine	73-76	insulin like growth factor 1	Homo sapiens	58-63
6815172-4	1982	Of the two reactions involved in the glycine-CO2 exchange, decarboxylation of glycine yielding the H-protein-bound aminomethyl moiety was not significantly affected by 100 microM Zn2+ or Cu2+, but carboxylation of the H-protein-bound aminomethyl moiety to form glycine was strongly inhibited by either Zn2+ or Cu2+.	Glycine	37-44	glycine cleavage system protein H	Gallus gallus	218-227
6815172-6	1982	The primary site of the action of divalent metal ions is likely to be not P-protein but H-protein, and the binding of metal ions with the H-protein-bound intermediate of glycine decarboxylation was assumed to account for the observed marked inhibition.	Glycine	170-177	glycine cleavage system protein H	Gallus gallus	88-97
6815172-4	1982	Of the two reactions involved in the glycine-CO2 exchange, decarboxylation of glycine yielding the H-protein-bound aminomethyl moiety was not significantly affected by 100 microM Zn2+ or Cu2+, but carboxylation of the H-protein-bound aminomethyl moiety to form glycine was strongly inhibited by either Zn2+ or Cu2+.	Glycine	78-85	glycine cleavage system protein H	Gallus gallus	99-108
6815172-6	1982	The primary site of the action of divalent metal ions is likely to be not P-protein but H-protein, and the binding of metal ions with the H-protein-bound intermediate of glycine decarboxylation was assumed to account for the observed marked inhibition.	Glycine	170-177	glycine cleavage system protein H	Gallus gallus	138-147
6815172-4	1982	Of the two reactions involved in the glycine-CO2 exchange, decarboxylation of glycine yielding the H-protein-bound aminomethyl moiety was not significantly affected by 100 microM Zn2+ or Cu2+, but carboxylation of the H-protein-bound aminomethyl moiety to form glycine was strongly inhibited by either Zn2+ or Cu2+.	Glycine	78-85	glycine cleavage system protein H	Gallus gallus	218-227
6815172-4	1982	Of the two reactions involved in the glycine-CO2 exchange, decarboxylation of glycine yielding the H-protein-bound aminomethyl moiety was not significantly affected by 100 microM Zn2+ or Cu2+, but carboxylation of the H-protein-bound aminomethyl moiety to form glycine was strongly inhibited by either Zn2+ or Cu2+.	Glycine	78-85	glycine cleavage system protein H	Gallus gallus	99-108
6815172-4	1982	Of the two reactions involved in the glycine-CO2 exchange, decarboxylation of glycine yielding the H-protein-bound aminomethyl moiety was not significantly affected by 100 microM Zn2+ or Cu2+, but carboxylation of the H-protein-bound aminomethyl moiety to form glycine was strongly inhibited by either Zn2+ or Cu2+.	Glycine	78-85	glycine cleavage system protein H	Gallus gallus	218-227
6128692-9	1982	It is concluded that the structural requirements for the inhibitory effect of MIF on the development of tolerance to morphine are very strict and that the following modifications in the structure of MIF result in the loss of activity (a) substitution of Gly or Val in place of Leu (b) replacement of Gly-NH2 with Gly-NHCH3 or beta-Ala-NH2 (c) removal of Gly, and (d) removal of Leu followed by cyclization of Pro-Gly.	Glycine	254-257	macrophage migration inhibitory factor	Rattus norvegicus	199-202
7120527-3	1982	Methionine, glycine, and phenylalanine concentrations were increased in the 15.6% BCAA group: methionine and glycine were decreased in the 100% BCAA groups.	Glycine	109-116	AT-rich interaction domain 4B	Homo sapiens	144-148
6128692-9	1982	It is concluded that the structural requirements for the inhibitory effect of MIF on the development of tolerance to morphine are very strict and that the following modifications in the structure of MIF result in the loss of activity (a) substitution of Gly or Val in place of Leu (b) replacement of Gly-NH2 with Gly-NHCH3 or beta-Ala-NH2 (c) removal of Gly, and (d) removal of Leu followed by cyclization of Pro-Gly.	Glycine	300-303	macrophage migration inhibitory factor	Rattus norvegicus	199-202
6757051-4	1982	One group of externally suppressible his4 mutations, designated Group II, have been shown to contain +1 G:C insertions in glycine codons and are suppressed by any one of five suppressor mutations described previously (SUF1, SUF3, SUF4, SUF5, and SUF6).	Glycine	122-129	trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase	Saccharomyces cerevisiae S288C	37-41
6288599-4	1982	The local conformation of Tyr-Gly-Gly-Phe-segment observed in Met-enkephalin is maintained in beta h-endorphin.	Glycine	30-33	proopiomelanocortin	Homo sapiens	62-76
6288599-4	1982	The local conformation of Tyr-Gly-Gly-Phe-segment observed in Met-enkephalin is maintained in beta h-endorphin.	Glycine	34-37	proopiomelanocortin	Homo sapiens	62-76
6757051-5	1982	The suppressor genes are believed to encode glycine tRNAs containing four base anticodons.--An analysis of spontaneous co-revertants of the Group II frameshift mutation his4-206 and leu2-3 has revealed the existence of eleven new Group II-specific suppressor genes (SUF15 through SUF25).	Glycine	44-51	trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase	Saccharomyces cerevisiae S288C	169-173
6757051-5	1982	The suppressor genes are believed to encode glycine tRNAs containing four base anticodons.--An analysis of spontaneous co-revertants of the Group II frameshift mutation his4-206 and leu2-3 has revealed the existence of eleven new Group II-specific suppressor genes (SUF15 through SUF25).	Glycine	44-51	3-isopropylmalate dehydrogenase	Saccharomyces cerevisiae S288C	182-188
7046464-8	1982	The mechanism is unclear, but enhancement of insulin absorption can be produced by glycine and AIB alone.	Glycine	83-90	insulin	Homo sapiens	45-52
7046464-9	1982	This raises the possibility of a link between the absorption of insulin and the glycine and AIB shared transport system, but excludes a primary metabolic effect because AIB is nonmetabolizable.	Glycine	80-87	insulin	Homo sapiens	64-71
7037624-5	1981	Insulin, 10(-6)M, enhanced 1-3H-glucosamine incorporation 54% and glycine incorporation to 42%.	Glycine	66-73	insulin	Gallus gallus	0-7
7060566-6	1982	A conformational transition of Met-enkephalin from the intramolecularly bonded to the unbonded one takes place at about 40 mol-% water in (C2H3)2SO, involving the Met-5 NH proton and the Tyr-Gly-Gly fragment.	Glycine	191-194	proopiomelanocortin	Homo sapiens	31-45
7060566-6	1982	A conformational transition of Met-enkephalin from the intramolecularly bonded to the unbonded one takes place at about 40 mol-% water in (C2H3)2SO, involving the Met-5 NH proton and the Tyr-Gly-Gly fragment.	Glycine	195-198	proopiomelanocortin	Homo sapiens	31-45
7100893-1	1982	The present paper describes the structural analysis of an abnormal hemoglobin variant of alpha-chain found in a Chinese woman in the Hechi district of the Zhuang Autonomous Region of Guangxi, and finds it to be hemoglobin Handsworth (alpha 18(A16) Gly leads to Arg).	Glycine	248-251	Fc gamma receptor and transporter	Homo sapiens	89-100
7067697-1	1982	This paper describes the solution conformation of the vasoactive peptide hormone des-Arg9-bradykinin (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe).	Glycine	114-117	kininogen 1	Homo sapiens	90-100
7044895-1	1981	A gene has been constructed which codes for an analog of human proinsulin in which the normal 35-amino acid connecting peptide is replaced by a "mini-C" peptide of six amino acids (Arg-Arg-Gly-Ser-Lys-Arg).	Glycine	189-192	insulin	Homo sapiens	63-73
7037624-7	1981	When both insulin and tri-iodo-thyronine were added to the culture medium, glucosamine incorporation was augmented by 156% and glycine incorporation was stimulated by 77%.	Glycine	127-134	insulin	Gallus gallus	10-17
7320944-14	1981	At 0.2 mM extracellular glycine, the relative contributions of each of these uptake routes to the total glycine flux were 42, 11, 15 and 16% for the gly, ASC, L and band 3 systems, respectively.	Glycine	104-111	PYD and CARD domain containing	Homo sapiens	154-157
6173233-8	1981	A preparation with the same properties was obtained by substituting glycine buffer (pH 2) for EG in the elution of Con A-induced IFN from silicic acid.	Glycine	68-75	interferon alpha 1	Homo sapiens	129-132
6975346-3	1981	Biologically active TCGF could also be eluted from the surface of these cells using an acid glycine buffer under conditions that maintained cell viability, and subcellular fractionation showed that almost all the TCGF activity was associated with the plasma membrane.	Glycine	92-99	interleukin 2	Homo sapiens	20-24
6268663-7	1981	The beta-melanotropin analogue (glycine[Gly](10)-beta-melanotropin) inhibited aldosterone production induced by beta-lipotropin or beta-melanotropin, but did not inhibit aldosterone production induced by ACTH(1-24) or angiotensin II.	Glycine	32-39	angiotensinogen	Rattus norvegicus	218-232
6174544-2	1981	Among the antibodies contained in a rabbit antiserum to synthetic peptide sequence TTHYGSLPQKAQGHRPQDEG (S82) of bovine myelin basic protein (residues 65-83 plus glycine), was a population reactive with a C-terminal determinant of S82 and cross-reactive with S79 (AQGHRPQDEG) but not S6 (AQGHRPQDENG).	Glycine	162-169	myelin basic protein	Bos taurus	120-140
6268663-7	1981	The beta-melanotropin analogue (glycine[Gly](10)-beta-melanotropin) inhibited aldosterone production induced by beta-lipotropin or beta-melanotropin, but did not inhibit aldosterone production induced by ACTH(1-24) or angiotensin II.	Glycine	40-43	angiotensinogen	Rattus norvegicus	218-232
6112249-4	1981	In rat spleen lymphocytes, THF-dependent conversion of glycine to serine was inhibited by SASP, with 50% inhibition occurring at 0.1 mM.	Glycine	55-62	aspartic peptidase retroviral like 1	Homo sapiens	90-94
6265056-5	1981	Patient fibrinogen purified with 2.1 M glycine migrated normally on immunoelectrophoresis and 7.5% polyacrylamide-SDS gel electrophoresis.	Glycine	39-46	fibrinogen beta chain	Homo sapiens	8-18
6792030-1	1981	The introduction of a crosslink between the amino groups of A1-glycine and B29-lysine of the insulin molecule leads to a marked decrease in sensitivity towards pepsin.	Glycine	63-70	insulin	Homo sapiens	93-100
6264603-3	1981	The location of glycine next to the carboxyl terminal prolinamide of calcitonin is consistent with indications that glycine is required for the enzymatic amidation of proline to the prolinamide.	Glycine	16-23	calcitonin related polypeptide alpha	Homo sapiens	69-79
6264603-3	1981	The location of glycine next to the carboxyl terminal prolinamide of calcitonin is consistent with indications that glycine is required for the enzymatic amidation of proline to the prolinamide.	Glycine	116-123	calcitonin related polypeptide alpha	Homo sapiens	69-79
7031225-14	1981	This study demonstrates that pyro-Glo-His-Gly suppresses serum hormonal and gastric secretory response to cephalic stimulation and reduces gastrin and pancreatic secretory responses to ordinary feeding or exogenous hormonal stimuli.	Glycine	42-45	gastrin	Canis lupus familiaris	139-146
7028141-1	1981	An intramolecular modification of insulin at the alpha-amino group of glycine (A1) and the epsilon-amino group of lysine (B29) was carried out.	Glycine	70-77	insulin	Homo sapiens	34-41
6940191-4	1981	Further degradation of porcine des-Arg(74)-C5a by carboxypeptidase Y removed glycine-73 and leucine-72 and decreased the intrinsic spasmogenic activity by >90%.	Glycine	77-84	complement C5a receptor 1	Homo sapiens	43-46
6263481-4	1981	One of the Drosophila actin genes, DmA4, is split within a glycine codon at position 13; none of the remaining five genes is interrupted in the analogous position.	Glycine	59-66	Actin 79B	Drosophila melanogaster	22-27
7209542-1	1981	The affinity of the amino terminal tetrapeptide of the beta chain of fibrin, Gly-His-Arg-Pro, for fibrinogen dramatically increases in the presence of 2 millimolar calcium ion.	Glycine	77-80	fibrinogen beta chain	Homo sapiens	98-108
6162590-2	1981	In a radioimmunoassay, peptides that extend toward the amino terminal from Ala34, such as [Tyr,Gly]-ACTH34-39, ACTH18-39, and ACTH, had greater affinity for the antibody, which suggests that the antiserum recognizes the peptide bond preceding the alanyl residue.	Glycine	95-98	proopiomelanocortin	Homo sapiens	100-104
7440562-2	1980	Glycine decarboxylase, tentatively called P-protein and considered a constituent of the glycine cleavage system, was purified to apparent homogeneity from chicken liver mitochondria.	Glycine	88-95	glycine decarboxylase	Gallus gallus	0-21
6266906-6	1981	After the drug was discontinued, though there was an enhancement in gastrin response in both saline and glycine perfused groups, the peak gastrin levels were reached earlier in the vagotomized dogs.	Glycine	104-111	gastrin	Canis lupus familiaris	68-75
6266906-0	1981	The effect of phenoxybenzamine on the gastrin response to glycine stimulation.	Glycine	58-65	gastrin	Canis lupus familiaris	38-45
6266906-2	1981	In the present study, the effect of phenoxybenzamine, a potent alpha-blocking agent, on the gastrin release in response to glycine perfusion (pH 7.0) of an isolated canine antral pouch was examined.	Glycine	123-130	gastrin	Canis lupus familiaris	92-99
6997175-2	1980	As expected, the infusion of insulin exhibited significant reduction of the release of glycine, proline, valine, phenylalanine, leucine, threonine and isoleucine.	Glycine	87-94	insulin	Homo sapiens	29-36
6778858-1	1980	Glycine decarboxylase, tentatively called P-protein as a constituent of the glycine cleavage system, was purified to near homogeneity from rat liver mitochondria.	Glycine	76-83	glycine decarboxylase	Rattus norvegicus	0-21
6778858-1	1980	Glycine decarboxylase, tentatively called P-protein as a constituent of the glycine cleavage system, was purified to near homogeneity from rat liver mitochondria.	Glycine	76-83	OCA2 melanosomal transmembrane protein	Rattus norvegicus	42-51
6778858-3	1980	In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM.	Glycine	51-58	OCA2 melanosomal transmembrane protein	Rattus norvegicus	93-102
6778858-3	1980	In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM.	Glycine	164-171	OCA2 melanosomal transmembrane protein	Rattus norvegicus	93-102
6997175-3	1980	As insulin, bradykinin lessened the release of 9 amino acids: Glycine, serine, ornithin, valine, leucine, isoleucine and tyrosine.	Glycine	62-69	kininogen 1	Homo sapiens	12-22
116223-5	1979	The S50K fragment begins with the sequence Val-Tyr-Gln-Pro-Gln-Pro-His-Pro-Gln-Pro-(Pro)-(Gly)-Tyr-Gly-His-( )-Val, a region with an extended conformation which is susceptible to proteolysis and connects this domain to the remainder of the fibronectin molecule.	Glycine	99-102	fibronectin 1	Homo sapiens	240-251
6776531-7	1980	The NH2-terminal sequence of CNBr II revealed the active site serine of factor D. The typical serine protease active site sequence (Gly-Asp-Ser-Gly-Gly-Pro  was found at residues 12-17.	Glycine	132-135	coagulation factor II, thrombin	Homo sapiens	94-109
6776531-7	1980	The NH2-terminal sequence of CNBr II revealed the active site serine of factor D. The typical serine protease active site sequence (Gly-Asp-Ser-Gly-Gly-Pro  was found at residues 12-17.	Glycine	144-147	coagulation factor II, thrombin	Homo sapiens	94-109
6776531-7	1980	The NH2-terminal sequence of CNBr II revealed the active site serine of factor D. The typical serine protease active site sequence (Gly-Asp-Ser-Gly-Gly-Pro  was found at residues 12-17.	Glycine	144-147	coagulation factor II, thrombin	Homo sapiens	94-109
6253107-3	1980	The immunoreactive site of LRF reacting with the antiserum resided between residues Tyr(5) and Gly(10)-NH2.	Glycine	95-98	CREB3 regulatory factor	Homo sapiens	27-30
7376793-0	1980	Glycine stimulated growth hormone release in man.	Glycine	0-7	growth hormone 1	Homo sapiens	19-33
7376793-4	1980	The dose of 4 or 8 g glycine induced a significant increase in serum GH (P less than 0.05 or P less than 0.001, respectively); however, a more pronounced and significant increase in serum GH levels was observed after infusion at a dose of 12 g glycine (P less than 0.001).	Glycine	21-28	growth hormone 1	Homo sapiens	69-71
7376793-4	1980	The dose of 4 or 8 g glycine induced a significant increase in serum GH (P less than 0.05 or P less than 0.001, respectively); however, a more pronounced and significant increase in serum GH levels was observed after infusion at a dose of 12 g glycine (P less than 0.001).	Glycine	21-28	growth hormone 1	Homo sapiens	188-190
7376793-4	1980	The dose of 4 or 8 g glycine induced a significant increase in serum GH (P less than 0.05 or P less than 0.001, respectively); however, a more pronounced and significant increase in serum GH levels was observed after infusion at a dose of 12 g glycine (P less than 0.001).	Glycine	244-251	growth hormone 1	Homo sapiens	188-190
7376793-5	1980	It was clearly observed that the dose-dependent GH release to intravenous glycine occurred in normal subjects.	Glycine	74-81	growth hormone 1	Homo sapiens	48-50
7356933-1	1980	Factor VIII has been purified approximately 300000-fold from bovine plasma by ammonium sulfate fractionation, glycine precipitation, DEAE-Sephadex column chromatography, sulfate--Sepharose column chromatography, Sephadex G-200 gel filtration, and factor X--Sepharose column chromatography.	Glycine	110-117	coagulation factor VIII	Bos taurus	0-11
540036-3	1979	Thrombin cleavage of the A- and B-peptides from fibrinogen in vitro was monitored by the appearance of N-terminal glycine, and an increase in glycine was shown in the FR antigen of patients with disseminated intravascular coagulation.	Glycine	114-121	fibrinogen beta chain	Homo sapiens	48-58
540036-3	1979	Thrombin cleavage of the A- and B-peptides from fibrinogen in vitro was monitored by the appearance of N-terminal glycine, and an increase in glycine was shown in the FR antigen of patients with disseminated intravascular coagulation.	Glycine	142-149	fibrinogen beta chain	Homo sapiens	48-58
505404-3	1979	Added in part by an advantage gained through addition of glycine to maintenance media, it is now possible to harvest urokinase at concentrations of the order of 800 CTA units per ml.	Glycine	57-64	plasminogen activator, urokinase	Homo sapiens	117-126
6771272-4	1980	The quantitative distribution of serine and glycine in this pentapeptide is consistent with the interpretation that the ovomucoid gene exists in two codominant allelic forms at one locus.	Glycine	44-51	ovomucoid	Coturnix japonica	120-129
6771272-6	1980	Intact third domains (positions 131 to 186) isolated from the two allelic forms of ovomucoid interact with bovine beta-trypsin in a similar but not identical manner; the complex with the glycine form dissociates more rapidly.	Glycine	187-194	ovomucoid	Coturnix japonica	83-92
6997872-7	1980	These results suggest that the antagonistic activity of a human insulin variant having leucine at position B24 or B25 can be assigned to the molecule with the sequence Gly-Leu-Phe-Tyr (residues B23-B26) in its active site.	Glycine	168-171	insulin	Homo sapiens	64-71
467440-3	1979	The purity of the isolated polypeptide P39 was confirmed by a further electrophoresis on an analytical dodecylsulfate gel and further elucidated by amino-terminal analysis which shows that glycine is the only amino-terminal amino acid of the purified polypeptide material.	Glycine	189-196	cyclin dependent kinase 5 regulatory subunit 2	Homo sapiens	39-42
477907-3	1979	The high-molecular aminopeptidase splits very slowly the N-terminal Leu when Gly is in adjacent position.	Glycine	77-80	carboxypeptidase Q	Homo sapiens	19-33
36154-1	1979	The chlorination of glycine by the myeloperoxidase-H2O2-Cl- system at acidic pH values yielded N-monochloroglycine and a mixture of HCN and ClCN.	Glycine	20-27	myeloperoxidase	Homo sapiens	35-50
468466-5	1979	An application of the method is demonstrated by measuring the increase in amino-terminal glycine in fibrinogen following the proteolytic action of thrombin.	Glycine	89-96	fibrinogen beta chain	Homo sapiens	100-110
468466-5	1979	An application of the method is demonstrated by measuring the increase in amino-terminal glycine in fibrinogen following the proteolytic action of thrombin.	Glycine	89-96	coagulation factor II, thrombin	Homo sapiens	147-155
632300-9	1978	The fact that all half-cystine and glycine residues and most nonpolar core residues of the insulin monomer are conserved is compatible with a three-dimensional structure of IGF-I similar to that of insulin.	Glycine	35-42	insulin like growth factor 1	Homo sapiens	173-178
458678-0	1979	GABA and glycine inhibit vasopressin release to carotid occlusion [proceedings].	Glycine	9-16	arginine vasopressin	Homo sapiens	25-36
43840-6	1979	In aqueous ethanol the X-Asc-Y-NH2 (X, Pro, Leu; Y, Gly, Ala, Val, Phg, Phe) containing N-terminal proline are more readily transformed to piperazine-2,5-dione derivatives, but compared to simple proline dipeptides the rate of this transformation is relatively slow because of the crowdedness of the tricyclic transitional state.	Glycine	52-55	PYD and CARD domain containing	Homo sapiens	25-28
429103-4	1979	It is proposed that this feature (in which Phe could be situated near Val and near the Arg-Gly bond of the A alpha chain in the three-dimensional structure of fibrinogen) may be especially advantageous for binding to the enzyme.	Glycine	91-94	fibrinogen beta chain	Homo sapiens	159-169
284388-5	1979	By labeling with [14C]dansyl chloride, an insulin intermediate with three amino-terminal residues, glycine, phenylalanine, and leucine, was identified.	Glycine	99-106	insulin	Homo sapiens	42-49
304104-6	1977	Noradrenaline and glycine decreased the spontaneous release of CRH from the hypothalamus but neither of these substances affected hypothalamic CRH content.	Glycine	18-25	corticotropin releasing hormone	Rattus norvegicus	63-66
629953-3	1978	For the trans isomers in Me2SO-d6, there is a hydrogen bond between the Gly CO group and one of the C-terminal primary amide hydrogens, and a beta turn involving the Gly-Pro-Ala-NH, section of the molecules.	Glycine	166-169	amyloid beta precursor protein	Homo sapiens	140-146
622050-0	1978	Stimulatory effect of glycine on human growth hormone secretion.	Glycine	22-29	growth hormone 1	Homo sapiens	39-53
667168-2	1978	The sequence of chicken histone H2A differs from the calf homologous histone by the deletion of one residue of histidine at position 123 or 124 and three conservative substitutions: a residue of serine replaces a residue of threonine at position 16, a residue of aspartic acid replaces a residue of glutamic acid at position 121 and a residue of alanine replaces a residue of glycine at position 128.	Glycine	376-383	H2A histone family, member J	Gallus gallus	24-35
303241-5	1977	Its amino acid composition and apparent molecular weight estimated by Sephadex G-25 chromatography, indicate that FTS is a nonapeptide of composition lysine, aspartic acid (or asparagine), serine 2, glutamic acid (or glutamine) 2, glycine 2, and alanine.	Glycine	231-238	AKT interacting protein	Homo sapiens	114-117
649058-5	1978	After protection of the N-terminal glycine residue of the A-chain by citraconylation, a biologically active PVP-insulin was obtained.	Glycine	35-42	insulin	Homo sapiens	112-119
31111-2	1978	Thrombin severs four ARG-GLY bonds in the alpha A and beta B chains of its molecule, on the side of the terminal-N.	Glycine	25-28	coagulation factor II, thrombin	Homo sapiens	0-8
24408196-10	1978	Amino acid compositions determined after acid hydrolysis show marked differences between L-1 and L-2, particularly with respect to the amino acids Lys, Phe, Ser, Gly and Leu.	Glycine	162-165	seed linoleate 13S-lipoxygenase-1	Glycine max	89-92
320194-9	1977	Thus, the affect of metK mutations on the regulation of glycine and methionine synthesis in Salmonella typhimurium appears to be due to either an altered S-adenosylmethionine synthetase or altered S-adenosylmethionine pools.	Glycine	56-63	methionine adenosyltransferase	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	20-24
913715-0	1977	[Increases of serum gastrin and growth hormone concentrations in subjects suffering from hyperthyroidism, hypothyroidism, and in patients with partial gastrectomy, and normal subjects in the per-oral administration of glycine].	Glycine	218-225	growth hormone 1	Homo sapiens	32-46
15657-2	1977	The N-terminal amino acid of glutamine synthetase is glycine.	Glycine	53-60	glutamate-ammonia ligase	Homo sapiens	29-49
28304909-3	1977	Glycine was the predominant amino acid of the vitellogenin 2.	Glycine	0-7	putative uncharacterized protein LOC400499	Homo sapiens	46-58
28304909-11	1977	Presumably much of the glycine released from the vitellogenin contributed to the serine pool.	Glycine	23-30	putative uncharacterized protein LOC400499	Homo sapiens	49-61
843718-0	1977	Vasopressin release by antagonists of GABA and glycine [proceedings].	Glycine	47-54	arginine vasopressin	Homo sapiens	0-11
320194-9	1977	Thus, the affect of metK mutations on the regulation of glycine and methionine synthesis in Salmonella typhimurium appears to be due to either an altered S-adenosylmethionine synthetase or altered S-adenosylmethionine pools.	Glycine	56-63	methionine adenosyltransferase	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	154-185
833824-4	1977	However, when Phe10 of beta cl-MSH is replaced by Gly, both activities are destroyed.	Glycine	50-53	msh homeobox 2	Homo sapiens	31-34
194605-1	1977	The polypeptides ACTH and ATCH4-10 (OI 63) witha sequence of amino acids H-Met-Glu-His-Phe-Arg-Trp-Gly-OH, have similar stimulating effects  on motor units in lower mammals.	Glycine	99-102	proopiomelanocortin	Homo sapiens	17-21
61715-4	1976	The histamine (H2)-receptor blocking drug metiamide (3.10(-5) M) abolished the positive chronotropic actions of both midodrine and glycine.	Glycine	131-138	histamine H2 receptor	Cavia porcellus	4-27
16229-4	1977	AChE identification together with autoradiographic tracing of glycine showed that large cholinergic motoneurons are accompanied by small glycine-accumulating neurons with short processes which form axo-somatic and axo-dendritic contacts with large neurons.	Glycine	137-144	acetylcholinesterase (Cartwright blood group)	Homo sapiens	0-4
1001848-2	1976	Biological activity of proinsulin and insulin modified at A1-glycine and B29-lysine.	Glycine	61-68	insulin	Homo sapiens	23-33
1001848-2	1976	Biological activity of proinsulin and insulin modified at A1-glycine and B29-lysine.	Glycine	61-68	insulin	Homo sapiens	26-33
1008857-3	1976	Insulin enhanced the transport rate of substrate amino acids from the A system(alpha-aminoisobutyric acid, L-proline, glycine, L-alanine and L-serine) in fibroblasts and osteoblasts from chick-embryo tissues, in mesenchymal cells (fibroblasts and smooth muscle cells) from immature rat uterus, in thymic lymphocytes from young rats and in chick-embryo fibroblasts from confluent secondary cultures.	Glycine	118-125	insulin	Gallus gallus	0-7
1002996-12	1976	Human C5a contains a COOH-terminal arginine which is essential for anaphylatoxin activity and a sequence of Gln-Leu-Gly-Arg-COOH at the COOH-terminus which compares favorably with that of human C3a (Gly-Leu-Ala-Arg-COOH).	Glycine	116-119	complement C5a receptor 1	Homo sapiens	6-9
996834-0	1976	Isolation of residual fibrinogen from a supernatant of plasma precipitated with 2.1 M glycine.	Glycine	86-93	fibrinogen beta chain	Homo sapiens	22-32
938662-6	1976	By the same method, acetylated lysine and glycine were identified for chicken lysozyme and horse myoglobin, respectively.	Glycine	42-49	myoglobin	Equus caballus	97-106
788133-3	1976	The growth hormone (GH) secretory response to glycine did not change according to the occurrence and/or magnitude of IRI release.	Glycine	46-53	growth hormone 1	Homo sapiens	4-18
788133-3	1976	The growth hormone (GH) secretory response to glycine did not change according to the occurrence and/or magnitude of IRI release.	Glycine	46-53	growth hormone 1	Homo sapiens	20-22
788133-4	1976	It was concluded that GH and IRI stimulatory properties of glycine given intravenously in large doses are completely unrelated.	Glycine	59-66	growth hormone 1	Homo sapiens	22-24
932041-4	1976	The labeled glycine was incubated with D-amino acid oxidase, an enzyme which, in the catalysis of the conversion of glycine to glyoxylic acid, specifically removes the hydrogen in the S configuration at carbon atom 2 of glycine.	Glycine	12-19	D-amino-acid oxidase	Rattus norvegicus	39-59
932041-4	1976	The labeled glycine was incubated with D-amino acid oxidase, an enzyme which, in the catalysis of the conversion of glycine to glyoxylic acid, specifically removes the hydrogen in the S configuration at carbon atom 2 of glycine.	Glycine	116-123	D-amino-acid oxidase	Rattus norvegicus	39-59
932041-4	1976	The labeled glycine was incubated with D-amino acid oxidase, an enzyme which, in the catalysis of the conversion of glycine to glyoxylic acid, specifically removes the hydrogen in the S configuration at carbon atom 2 of glycine.	Glycine	116-123	D-amino-acid oxidase	Rattus norvegicus	39-59
939805-1	1976	The properties of fibrinogen extracted by a precipitation method using glycine at ambient temperatures near neutral pH are described.	Glycine	71-78	fibrinogen beta chain	Homo sapiens	18-28
57115-3	1976	In the present study myelin basic protein from bovine spinal cord was chromatographed on carboxymethylcellulose at pH 10.4 in glycine buffer/2 M urea.	Glycine	126-133	myelin basic protein	Bos taurus	21-41
239413-5	1975	To induce the release of gastrin, one or both antra were irrigated with 0.2-percent acetylcholine or with 1 M glycine.	Glycine	110-117	gastrin	Canis lupus familiaris	25-32
179749-7	1976	The hydrolysis of Gly-His-Gly and A-I was inhibited by histidyl-leucine and angiotensin II, both products of the hydrolysis of A-I.	Glycine	18-21	angiotensinogen	Homo sapiens	34-37
179749-7	1976	The hydrolysis of Gly-His-Gly and A-I was inhibited by histidyl-leucine and angiotensin II, both products of the hydrolysis of A-I.	Glycine	18-21	angiotensinogen	Homo sapiens	76-90
179749-7	1976	The hydrolysis of Gly-His-Gly and A-I was inhibited by histidyl-leucine and angiotensin II, both products of the hydrolysis of A-I.	Glycine	18-21	angiotensinogen	Homo sapiens	127-130
954221-1	1976	Intravenous glycine injection (250 mg/kg of body weight) resulted in growth hormone release in normal children but not in those with growth hormone deficiency diagnosed by insulin-induced hypoglycaemia.	Glycine	12-19	growth hormone 1	Homo sapiens	69-83
2300-1	1976	The inactivation of the neurohypophyseal hormones arginine vasopressin and oxytocin, both 14C-labelled in the C-terminal glycine residue, by enzymes present in kidney homogenates of various species has been investigated, and some of the enzymes responsible have been partially purified and characterized.	Glycine	121-128	arginine vasopressin	Homo sapiens	24-40
2300-1	1976	The inactivation of the neurohypophyseal hormones arginine vasopressin and oxytocin, both 14C-labelled in the C-terminal glycine residue, by enzymes present in kidney homogenates of various species has been investigated, and some of the enzymes responsible have been partially purified and characterized.	Glycine	121-128	arginine vasopressin	Homo sapiens	59-70
2300-3	1976	Degradation of arginine vasopressin is slower than oxytocin in all species studied, and appears to occur by a different overall mechanism since cleavage of the Pro-Arg bond is more significant than hydrolysis of the Arg-Gly bond.	Glycine	220-223	arginine vasopressin	Homo sapiens	24-35
173719-2	1976	Addition of L-3,4-dehydroproline to the culture medium inhibited markedly the incorporation of [14C]glycine and L-[3H]lysine into the collagen of 3T3 cells, but there was only slight inhibition of the incorporation of the radiolabeled amino acids into total cellular proteins, indicating that the action of L-3,4-dehydroproline is specific for collagen.	Glycine	95-107	skull morphology 4	Mus musculus	12-15
1222231-0	1975	Growth hormone release by glycine injected intravenously in 22 healthy sexually immature children.	Glycine	26-33	growth hormone 1	Homo sapiens	0-14
1116488-1	1975	Arginine-vasopressin and oxytocin, both 14C-labeled in the glycine residue, are enzymatically inactivated by rat kidney supernatant.	Glycine	59-66	arginine vasopressin	Rattus norvegicus	9-20
1116488-3	1975	Both oxytocin and vasopressin are degraded by an enzyme which cleaves their Pro-X bonds, to release Leu-Gly-NH2 from oxytocin and Arg-Gly-NH2 from vasopressin.	Glycine	104-107	arginine vasopressin	Rattus norvegicus	18-29
4297-3	1976	Two mumole of glycine was also effective in elevating PRL levels.	Glycine	14-21	prolactin	Rattus norvegicus	54-57
4297-6	1976	The results suggest that GABA and glycine may play a role in the neural regulation of PRL secretion.	Glycine	34-41	prolactin	Rattus norvegicus	86-89
970031-4	1976	The analysis of the isoaccepting tRNA by reversed-phase chromatography (RPC-5 system) showed the presence of 5 fractions for glycine and leucine, 3 for tyrosine, alanine and valine, 2 for arginine and 1 for phenylalanine.	Glycine	125-132	mitochondrially encoded tRNA glycine	Homo sapiens	33-37
171639-5	1975	D-3-phosphoglycerate dehydrogenase and phosphoserine phosphatase activities were higher in livers from chicks fed 2% protein, 2% protein + 2% glycine, and 2% protein + 2% L-serine diets when compared to those from chicks fed low protein diets with supplemental methionine or cysteine.	Glycine	142-149	phosphoglycerate dehydrogenase	Gallus gallus	0-34
1133566-1	1975	After two daily ovine prolactin injections in rats, significant increases in jejunal absorption of glucose, glycine and proline, as well as of fluid and NaCl, occurred.	Glycine	108-115	prolactin	Rattus norvegicus	22-31
1117054-1	1975	Changes in blood levels of glucagon, insulin and glucose in response to infusions of alanine and glycine have been studied in postabsorptive and fasting obese human subjects.	Glycine	97-104	insulin	Homo sapiens	37-44
1114483-0	1975	Estrogen induced appearance of N-terminal glycine from chromatographically purified fibrinogen.	Glycine	42-49	fibrinogen beta chain	Homo sapiens	84-94
239413-8	1975	Endogenous gastrin released from antra by acetylcholine or glycine caused identical changes in the recordings as exogenous pentagastrin.	Glycine	59-66	gastrin	Canis lupus familiaris	11-18
4462579-5	1974	Urate synthesis from glycine, glutamine, NH(4)Cl, asparagine, alanine, histidine and a mixture of 21 amino acids was obtained on inclusion of insulin in the perfusion medium.	Glycine	21-28	insulin	Gallus gallus	142-149
4555980-2	1972	The analog in which glycine was substituted for histidine at position 2, [Gly(2)]LRF, behaves as a partial agonist releasing less than 50 percent of the luteinizing hormone secreted at maximum concentrations of the releasing factor, while the analog in which histidine at position 2 is deleted has no significant agonist activity at any of the doses tested.	Glycine	74-77	zinc finger and BTB domain containing 7a	Rattus norvegicus	81-84
4748828-8	1973	Rat liver gamma-glutamylcysteine synthetase activity was inhibited by GSH and activated by glycine.	Glycine	91-98	glutamate-cysteine ligase, catalytic subunit	Rattus norvegicus	10-43
4556826-0	1972	(Gly 2 )LRF and des-His  2 -LRF.	Glycine	1-4	CREB3 regulatory factor	Homo sapiens	8-11
4375978-4	1974	It appears to be related to the beta-MSH species of mammalian species but has only the sequence -His-Phe-Arg-Trp- in common with the heptapeptide core -Met-Glu-His-Phe-Arg-Trp-Gly- which is characteristic not only of the MSH peptides but also of the adrenocorticotrophins and lipotrophins studied so far.	Glycine	176-179	proopiomelanocortin	Homo sapiens	32-40
4200724-5	1973	Strychnine binding is saturable, with affinity constants for glycine and strychnine of 10 and 0.03 muM, respectively.	Glycine	61-68	latexin	Homo sapiens	99-102
4761825-0	1973	The determination of optimum glycine concentration for the perparation of human fibrinogen at ambient temperatures.	Glycine	29-36	fibrinogen beta chain	Homo sapiens	80-90
4708157-0	1973	Glycine inhibition of L-asparagine amidohydrolase activity.	Glycine	0-7	asparaginase and isoaspartyl peptidase 1	Homo sapiens	22-49
5029862-0	1972	The reduction of cytochrome c by glycine.	Glycine	33-40	cytochrome c, somatic	Homo sapiens	17-29
5117532-0	1971	The substrate recognition site of collagen proline hydroxylase: the hydroxylation of -X-Pro-Gly- sequences in bradykinin analogs and other peptides.	Glycine	92-95	kininogen 1	Homo sapiens	110-120
4399668-0	1971	Glycine-amide effect on the vasopressin stimulated sodium and water transport across toad bladder.	Glycine	0-7	arginine vasopressin	Homo sapiens	28-39
18961000-4	1971	The order in terms of secondary ligands has been found to be ASPA > Gly > Aln and Gly > Aln > ASPA with iminodiacetic and nitrilotriacetic acid as primary ligands respectively (ASPA = aspartic acid, Gly = glycine, Aln = dl-alanine).	Glycine	71-74	aspartoacylase	Homo sapiens	61-65
18961000-4	1971	The order in terms of secondary ligands has been found to be ASPA > Gly > Aln and Gly > Aln > ASPA with iminodiacetic and nitrilotriacetic acid as primary ligands respectively (ASPA = aspartic acid, Gly = glycine, Aln = dl-alanine).	Glycine	88-91	aspartoacylase	Homo sapiens	106-110
18961000-4	1971	The order in terms of secondary ligands has been found to be ASPA > Gly > Aln and Gly > Aln > ASPA with iminodiacetic and nitrilotriacetic acid as primary ligands respectively (ASPA = aspartic acid, Gly = glycine, Aln = dl-alanine).	Glycine	88-91	aspartoacylase	Homo sapiens	106-110
18961000-4	1971	The order in terms of secondary ligands has been found to be ASPA > Gly > Aln and Gly > Aln > ASPA with iminodiacetic and nitrilotriacetic acid as primary ligands respectively (ASPA = aspartic acid, Gly = glycine, Aln = dl-alanine).	Glycine	88-91	aspartoacylase	Homo sapiens	106-110
18961000-4	1971	The order in terms of secondary ligands has been found to be ASPA > Gly > Aln and Gly > Aln > ASPA with iminodiacetic and nitrilotriacetic acid as primary ligands respectively (ASPA = aspartic acid, Gly = glycine, Aln = dl-alanine).	Glycine	88-91	aspartoacylase	Homo sapiens	106-110
18961000-4	1971	The order in terms of secondary ligands has been found to be ASPA > Gly > Aln and Gly > Aln > ASPA with iminodiacetic and nitrilotriacetic acid as primary ligands respectively (ASPA = aspartic acid, Gly = glycine, Aln = dl-alanine).	Glycine	217-224	aspartoacylase	Homo sapiens	106-110
18961000-4	1971	The order in terms of secondary ligands has been found to be ASPA > Gly > Aln and Gly > Aln > ASPA with iminodiacetic and nitrilotriacetic acid as primary ligands respectively (ASPA = aspartic acid, Gly = glycine, Aln = dl-alanine).	Glycine	217-224	aspartoacylase	Homo sapiens	106-110
5123875-2	1971	Isolated chick embryo heart cells were used to investigate the mode of action of insulin on the transport of three naturally occurring amino acids: l-proline, l-serine and glycine.	Glycine	172-179	insulin	Gallus gallus	81-88
5653209-8	1968	Rats pretreated with phenobarbital at a dose level of 60 mg/kg with induction of cytochrome P-450 synthesis showed a minor increase in early labeling when glycine-2-(14)C but not when delta ALA-4-(14)C was used as precursor.	Glycine	155-162	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	81-97
4309308-8	1969	Insulin increased the uptake by isolated heart cells of several (14)C-labelled naturally occurring amino acids; however, the fraction of amino acid taken up by the cells that was recovered free intracellularly, and therefore the concentration ratio (between intracellular water and medium), was enhanced by the hormone only with glycine, proline, serine, threonine, histidine and methionine.	Glycine	329-336	insulin	Gallus gallus	0-7
6023254-1	1967	Human transferrin D(1) obtained from an Australian aborigine was found to have the same substitution of glycine for aspartic acid in peptide 1C previously shown in transferrin D(1) from an American Negro.	Glycine	104-111	transferrin	Homo sapiens	6-17
5660637-1	1968	The effect of insulin on glycine and leucine accumulation.	Glycine	25-32	insulin	Gallus gallus	14-21
6023254-1	1967	Human transferrin D(1) obtained from an Australian aborigine was found to have the same substitution of glycine for aspartic acid in peptide 1C previously shown in transferrin D(1) from an American Negro.	Glycine	104-111	transferrin	Homo sapiens	164-175
17809412-2	1965	There is a difference in one peptide, and amino acid analyses indicate that an aspartic acid residue in transferrin C is replaced probably by a glycine residue in transferrin D(1).	Glycine	144-151	transferrin	Homo sapiens	104-115
17809412-2	1965	There is a difference in one peptide, and amino acid analyses indicate that an aspartic acid residue in transferrin C is replaced probably by a glycine residue in transferrin D(1).	Glycine	144-151	transferrin	Homo sapiens	163-174
14073163-0	1963	THE PREPARATION AND SOME PROPERTIES OF FIBRINOGEN PRECIPITATED FROM HUMAN PLASMA BY GLYCINE.	Glycine	84-91	fibrinogen beta chain	Homo sapiens	39-49
14294804-4	1965	Fibrinogen-tellurite-glycine plates were very useful for the isolation of staphylococci from milk in the presence of other microorganisms and for the simultaneous identification of coagulase positive strains.	Glycine	21-28	fibrinogen beta chain	Homo sapiens	0-10
14348196-14	1965	Glycine and alpha-oxobutyric acid were present in the acid hydrolysate, showing that both possible pathways of a beta-elimination reaction were involved.	Glycine	0-7	amyloid beta precursor protein	Homo sapiens	111-117
14362610-0	1955	The effect of vitamin B12 on some aspects of glycine metabolism.	Glycine	45-52	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	22-25
13702862-0	1961	Effect of growth hormone on conjugation of ingested glycine with aromatic acids.	Glycine	52-59	growth hormone 1	Homo sapiens	10-24
13926303-0	1961	The effect of growth hormone on the incorporation of N15 from ammonium citrate, glycine, L-aspartic acid, L-alanine and L-glutamic acid into amino acids of liver protein.	Glycine	80-87	growth hormone 1	Homo sapiens	14-28
13856105-0	1960	N-Terminal glycine analysis for the determination of the proteolytic activity of thrombin.	Glycine	11-18	coagulation factor II, thrombin	Homo sapiens	81-89
14820796-0	1951	The effect of vitamin B12 on the conversion of glycine to choline.	Glycine	47-54	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	22-25
14827881-0	1951	Toxicity of glycine for vitamin B12-deficient chicks.	Glycine	12-19	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	32-35
14802364-0	1951	EFFECT of ACTH on the incorporation of C14 of glycine in tissue proteins.	Glycine	46-53	proopiomelanocortin	Homo sapiens	10-14
33440065-0	2021	Preparation of Graphene Quantum Dots with Glycine as Nitrogen Source and its Interaction with Human Serum Albumin.	Glycine	42-49	albumin	Homo sapiens	100-113
33844328-8	2021	This new strategy shows slight improvements over an alternative side chain perturbation strategy for a set T4 lysozyme mutations lacking proline and glycine, and yields good agreement with experiment for a set of T4 lysozyme proline and glycine mutations not previously studied.	Glycine	149-156	lysozyme	Homo sapiens	110-118
33119191-8	2021	Finally, strychnine-sensitive glycine receptors (GlyRs) remained resilient to Abeta-induced changes and their activation reversed LC hyperexcitability.	Glycine	30-37	amyloid beta precursor protein	Homo sapiens	78-83
33976221-2	2021	Receptor activation involves glycine- and glutamate-stabilized closure of the GluN1 and GluN2 subunit ligand binding domains that is allosterically regulated by the amino-terminal domain (ATD).	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	78-83
34058193-6	2021	On "conventional" GluN1/GluN2 NMDA receptors, glycine (or D-serine) acts in concert with glutamate as a mandatory co-agonist to set the level of receptor activity.	Glycine	46-53	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	18-23
34058193-8	2021	On "unconventional" GluN1/GluN3 NMDARs, glycine acts as the sole agonist directly triggering opening of excitatory glycinergic channels recently shown to be physiologically relevant.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	20-25
34020077-10	2021	Unerupted teeth were significantly more common in patients with alpha1 and alpha2 glycine variants or substitutions than in those with haploinsufficiency variants.	Glycine	82-89	glycoprotein hormone subunit alpha 2	Homo sapiens	75-81
34044180-1	2021	BACKGROUND: A strong association of obesity and insulin resistance with increased circulating levels of branched-chain and aromatic amino acids and decreased glycine levels has been recognized in human subjects for decades.	Glycine	158-165	insulin	Homo sapiens	48-55
34006909-9	2021	The integration of metabolic and immune data indicated a molecular signature constituted by IL-6, IL1-ra, DMG, CCL4, Ile, Gly and IL-8, which could discriminate patients and healthy subjects and could represent a candidate tool in the diagnosis of new-onset psoriasis.	Glycine	122-125	interleukin 6	Homo sapiens	92-96
33976221-6	2021	Glycine binding to GluN1 has no detectable effect, but unlocks the receptor for activation so that glycine and glutamate together drive an altered activation trajectory that is consistent with ATD dimer separation and rotation.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	19-24
33976221-6	2021	Glycine binding to GluN1 has no detectable effect, but unlocks the receptor for activation so that glycine and glutamate together drive an altered activation trajectory that is consistent with ATD dimer separation and rotation.	Glycine	99-106	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	19-24
33962943-5	2021	The alpha5beta1-fibronectin complex revealed simultaneous interactions at the arginine-glycine-aspartate loop, the synergy site, and a newly identified binding site proximal to adjacent to metal ion-dependent adhesion site, inducing the translocation of helix alpha1 to secure integrin opening.	Glycine	87-94	fibronectin 1	Homo sapiens	16-27
33965399-0	2021	Ethanol inhibition of lateral orbitofrontal cortex neuron excitability is mediated via dopamine D1/D5 receptor-induced release of astrocytic glycine.	Glycine	141-148	dopamine receptor D1	Homo sapiens	87-110
33931940-5	2021	The characterization of Fn-modified surfaces showed that Fn grating via phosphonate has led to the highest amount of Fn cell-binding site (RGD, arginine, glycine, and aspartate) available on the surface.	Glycine	154-161	fibronectin 1	Homo sapiens	24-26
33831352-4	2021	We further identified that a total of 15 proteinogenic AAs are also able to activate TOR, and the first AAs generated from plant specific nitrogen assimilation (glutamine), sulfur assimilation (cysteine), and glycolate cycle (glycine), exhibit the highest potency.	Glycine	226-233	target of rapamycin	Arabidopsis thaliana	85-88
32767245-9	2021	Total testosterone was positively correlated with some amino acids, while prolactin was negatively correlated with glycine (P   0.05 for all).	Glycine	115-122	prolactin	Homo sapiens	74-83
33877377-3	2021	3T3-L1 cells were transfected with siRNA for the glycine (Glrb) and TNF1a (Tnfrsf1a) receptors and confirmed by confocal microscopy.	Glycine	49-56	glycine receptor, beta subunit	Mus musculus	58-62
33877377-6	2021	RESULTS: Glycine decreased the expression and concentration of TNF-alpha and IL-6; this effect did not occur in the absence of TNF-alpha receptor due to siRNA.	Glycine	9-16	tumor necrosis factor	Mus musculus	63-72
33877377-6	2021	RESULTS: Glycine decreased the expression and concentration of TNF-alpha and IL-6; this effect did not occur in the absence of TNF-alpha receptor due to siRNA.	Glycine	9-16	interleukin 6	Mus musculus	77-81
33877377-7	2021	In contrast, glycine produced only slight changes in the expression of TNF-alpha and IL-6 in the absence of the glycine receptor due to siRNA.	Glycine	13-20	tumor necrosis factor	Mus musculus	71-80
33877377-7	2021	In contrast, glycine produced only slight changes in the expression of TNF-alpha and IL-6 in the absence of the glycine receptor due to siRNA.	Glycine	13-20	interleukin 6	Mus musculus	85-89
33877377-9	2021	CONCLUSION: These findings support the idea that glycine could partially inhibit the binding of TNF-alpha to its receptor and provide clues about the mechanisms by which glycine inhibits the secretion of pro-inflammatory adipokines in adipocytes through the TNF-alpha receptor.	Glycine	49-56	tumor necrosis factor	Mus musculus	96-105
33877377-9	2021	CONCLUSION: These findings support the idea that glycine could partially inhibit the binding of TNF-alpha to its receptor and provide clues about the mechanisms by which glycine inhibits the secretion of pro-inflammatory adipokines in adipocytes through the TNF-alpha receptor.	Glycine	170-177	tumor necrosis factor	Mus musculus	96-105
33939273-0	2021	Comprehensive metabolomic profiling in early IgA nephropathy patients reveals urine glycine as a prognostic biomarker.	Glycine	84-91	CD79a molecule	Homo sapiens	45-48
33931940-5	2021	The characterization of Fn-modified surfaces showed that Fn grating via phosphonate has led to the highest amount of Fn cell-binding site (RGD, arginine, glycine, and aspartate) available on the surface.	Glycine	154-161	fibronectin 1	Homo sapiens	57-59
33931940-5	2021	The characterization of Fn-modified surfaces showed that Fn grating via phosphonate has led to the highest amount of Fn cell-binding site (RGD, arginine, glycine, and aspartate) available on the surface.	Glycine	154-161	fibronectin 1	Homo sapiens	57-59
33869785-5	2021	Methods/Results: Our metabolomic analysis suggests that forced expression of Snail accompanied reduced diversion of glycolytic metabolites to the serine/glycine metabolic shunt, a critical metabolic branch that distributes glucose catabolic intermediates to the major anabolic pathways.	Glycine	153-160	snail family transcriptional repressor 1	Homo sapiens	77-82
33922434-2	2021	The purpose of this study was to determine if the glycine-conjugated bile acids glycocholic acid (GCA), glycodeoxycholic acid (GDCA), and glycoursodeoxycholic acid (GUDCA) can protect retinal pigment epithelial (RPE) cells against oxidative damage and inhibit vascular endothelial growth factor (VEGF)-induced angiogenesis in choroidal endothelial cells (CECs).	Glycine	50-57	vascular endothelial growth factor A	Homo sapiens	260-294
33922434-2	2021	The purpose of this study was to determine if the glycine-conjugated bile acids glycocholic acid (GCA), glycodeoxycholic acid (GDCA), and glycoursodeoxycholic acid (GUDCA) can protect retinal pigment epithelial (RPE) cells against oxidative damage and inhibit vascular endothelial growth factor (VEGF)-induced angiogenesis in choroidal endothelial cells (CECs).	Glycine	50-57	vascular endothelial growth factor A	Homo sapiens	296-300
33959410-6	2021	The scFv combinatorial library was constructed from cDNA repertoire of variable regions of heavy chain (VH) and light chain (VL) fusions connected by a flexible glycine-serine linker, using splicing by overlap extension PCR (SOE-PCR).	Glycine	161-168	immunglobulin heavy chain variable region	Homo sapiens	4-8
33307094-7	2021	FAT10 affected autophagy through modulating SIRT1 degradation, which resulted in reduced SIRT1 nuclear translocation and inhibited SIRT1 activity via its C-terminal glycine residues.	Glycine	165-172	sirtuin 1	Rattus norvegicus	44-49
33869785-8	2021	Conclusion: This study has revealed a novel molecular link that integrates the serine/glycine metabolism with the Snail-mediated EMT program in cancer cells.	Glycine	86-93	snail family transcriptional repressor 1	Homo sapiens	114-119
33854215-3	2021	It identified "mutational hotspots" (PM1) in the collagen IV alpha5, alpha3 and alpha4 chains including position 1 Glycine residues in the Gly-X-Y repeats in the intermediate collagenous domains; and Cysteine residues in the carboxy non-collagenous domain (PP3).	Glycine	115-122	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3	Homo sapiens	69-86
33687436-8	2021	Nevertheless, treatment with glycine significantly ameliorated mitochondrial dysfunction, oxidative stress and apoptosis, glycine also regulated [Ca 2+]i levels and IP3R1 cellular distribution, which further protects oocyte maturation in ABT-199-induced porcine oocytes.	Glycine	122-129	inositol 1,4,5-trisphosphate receptor type 1	Homo sapiens	165-170
33506579-0	2021	Arabidopsis lysin motif/F-box-containing protein InLYP1 fine-tunes glycine metabolism by degrading glycine decarboxylase GLDP2.	Glycine	67-74	glycine decarboxylase P-protein 2	Arabidopsis thaliana	121-126
33506579-0	2021	Arabidopsis lysin motif/F-box-containing protein InLYP1 fine-tunes glycine metabolism by degrading glycine decarboxylase GLDP2.	Glycine	99-106	glycine decarboxylase P-protein 2	Arabidopsis thaliana	121-126
33506579-10	2021	Collectively, these results shed light on the function of plant intracellular LysM-containing proteins and suggest that InLYP1 may deplete GLDP2 to facilitate glycine decarboxylation in Arabidopsis.	Glycine	159-166	glycine decarboxylase P-protein 2	Arabidopsis thaliana	139-144
33869785-6	2021	Our gene expression profiling and molecular characterization revealed that Snail actively suppressed the expression of glycine decarboxylase (GLDC), a key enzyme on the serine/glycine metabolic shunt, through binding to an evolutionarily conserved E-box motif and thereby inhibiting the promoter of the GLDC gene.	Glycine	119-126	snail family transcriptional repressor 1	Homo sapiens	75-80
33737524-6	2021	In comparison to untreated controls, treatment of EJ28Luc cells with 213Bi-anti-EGFR-MAb resulted in a significantly decreased incorporation of 13C from [U-13C6]glucose into alanine, aspartate, glutamate, glycine, proline and serine.	Glycine	205-212	epidermal growth factor receptor	Homo sapiens	80-84
33738852-3	2021	The objective of the present study was to investigate the protective effects of glycine on sodium fluoride (NaF) exposure and the possible underlying mechanisms in a porcine testicular Sertoli cell line model.	Glycine	80-87	C-X-C motif chemokine ligand 8	Homo sapiens	108-111
33738852-4	2021	Cellular viability and proliferation were examined following NaF exposure and glycine supplementation, and glycine dramatically ameliorated the decreases in NaF-induced porcine testicular Sertoli cell viability and proliferation.	Glycine	107-114	C-X-C motif chemokine ligand 8	Homo sapiens	157-160
33738852-5	2021	Further investigations revealed that glycine decreased NaF-induced intracellular reactive oxygen species production, DNA fragment accumulation, and the apoptosis incidence in the porcine testicular Sertoli cell line; in addition, glycine improved mitochondrial function and ATP production.	Glycine	37-44	C-X-C motif chemokine ligand 8	Homo sapiens	55-58
33738852-5	2021	Further investigations revealed that glycine decreased NaF-induced intracellular reactive oxygen species production, DNA fragment accumulation, and the apoptosis incidence in the porcine testicular Sertoli cell line; in addition, glycine improved mitochondrial function and ATP production.	Glycine	230-237	C-X-C motif chemokine ligand 8	Homo sapiens	55-58
33738852-6	2021	Notably, results of the SPiDER-beta-Gal analysis suggested that glycine alleviated NaF-induced cellular senescence and downregulated P53, P21, HMGA2, and P16INK4a gene expression in the porcine testicular Sertoli cell line.	Glycine	64-71	C-X-C motif chemokine ligand 8	Homo sapiens	83-86
33738852-6	2021	Notably, results of the SPiDER-beta-Gal analysis suggested that glycine alleviated NaF-induced cellular senescence and downregulated P53, P21, HMGA2, and P16INK4a gene expression in the porcine testicular Sertoli cell line.	Glycine	64-71	tumor protein p53	Homo sapiens	133-136
33738852-6	2021	Notably, results of the SPiDER-beta-Gal analysis suggested that glycine alleviated NaF-induced cellular senescence and downregulated P53, P21, HMGA2, and P16INK4a gene expression in the porcine testicular Sertoli cell line.	Glycine	64-71	cyclin dependent kinase inhibitor 2A	Homo sapiens	154-162
33738852-7	2021	Collectively, the beneficial effects of glycine alleviate NaF-induced oxidative stress, apoptosis and senescence, and together with our previous findings, support the hypothesis that glycine plays an important role in protecting against NaF exposure-induced impairments in the porcine testicular Sertoli cell line.	Glycine	40-47	C-X-C motif chemokine ligand 8	Homo sapiens	58-61
33738852-7	2021	Collectively, the beneficial effects of glycine alleviate NaF-induced oxidative stress, apoptosis and senescence, and together with our previous findings, support the hypothesis that glycine plays an important role in protecting against NaF exposure-induced impairments in the porcine testicular Sertoli cell line.	Glycine	183-190	C-X-C motif chemokine ligand 8	Homo sapiens	58-61
33738852-7	2021	Collectively, the beneficial effects of glycine alleviate NaF-induced oxidative stress, apoptosis and senescence, and together with our previous findings, support the hypothesis that glycine plays an important role in protecting against NaF exposure-induced impairments in the porcine testicular Sertoli cell line.	Glycine	183-190	C-X-C motif chemokine ligand 8	Homo sapiens	237-240
33721904-9	2021	Molecular modeling and sequence comparison with other Catharanthus roseus receptor-like kinase 1L (CrRLK1L) receptor family members revealed that the mutated glycine in fer-ts is highly conserved, but is not located within the recently characterized RALF23 and LORELI-LIKE-GLYCOPROTEIN 2 binding domains, perhaps suggesting that fer-ts phenotypes may not be directly due to loss of binding to RALF1 peptides.	Glycine	158-165	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	169-172
33721904-9	2021	Molecular modeling and sequence comparison with other Catharanthus roseus receptor-like kinase 1L (CrRLK1L) receptor family members revealed that the mutated glycine in fer-ts is highly conserved, but is not located within the recently characterized RALF23 and LORELI-LIKE-GLYCOPROTEIN 2 binding domains, perhaps suggesting that fer-ts phenotypes may not be directly due to loss of binding to RALF1 peptides.	Glycine	158-165	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	329-332
33721904-9	2021	Molecular modeling and sequence comparison with other Catharanthus roseus receptor-like kinase 1L (CrRLK1L) receptor family members revealed that the mutated glycine in fer-ts is highly conserved, but is not located within the recently characterized RALF23 and LORELI-LIKE-GLYCOPROTEIN 2 binding domains, perhaps suggesting that fer-ts phenotypes may not be directly due to loss of binding to RALF1 peptides.	Glycine	158-165	rapid alkalinization factor 1	Arabidopsis thaliana	393-398
33756123-7	2021	Inhibitors of the glycine transporters GlyT1 and GlyT2 lowered levels of PPIX and markers of oxidative stress selectively in K56211B4 cells, and in primary erythroid cultures from an EPP patient.	Glycine	18-25	solute carrier family 6 member 9	Homo sapiens	39-44
33783984-0	2021	Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial.	Glycine	0-7	insulin	Homo sapiens	162-169
33656776-0	2021	Glycine substitution mutation of COL5A1 in classic Ehlers-Danlos syndrome: a case report and literature review.	Glycine	0-7	collagen type V alpha 1 chain	Homo sapiens	33-39
31829471-6	2021	In one of the best fermenting strains (strain 4.6), insertion was found to occur within the ORF of a homologue to Saccharomyces cerevisiae gene HEM25 (YDL119C), encoding a mitochondrial glycine transporter required for heme synthesis.	Glycine	186-193	Hem25p	Saccharomyces cerevisiae S288C	144-149
33411976-0	2021	Cytoplasmic granule formation by FUS-R495X is attributable to arginine methylation in all Gly-rich, RGG1 and RGG2 domains.	Glycine	90-93	FUS RNA binding protein	Homo sapiens	33-36
33566385-5	2021	PRL-3 promoted glucose uptake and lactate excretion, enhanced the levels of proteins regulating glycolysis and enzymes in the serine/glycine synthesis pathway, a side branch of glycolysis.	Glycine	133-140	protein tyrosine phosphatase 4A3	Homo sapiens	0-5
33658720-1	2021	The human glycine transporter 1 (GlyT1) regulates glycine-mediated neuronal excitation and inhibition through the sodium- and chloride-dependent reuptake of glycine1-3.	Glycine	10-17	solute carrier family 6 member 9	Homo sapiens	33-38
33275980-7	2021	Genetic variants at several NAFLD/NASH loci were nominally associated with increased levels of 7-Keto- and glycine-conjugated forms of BAs, and the NAFLD risk allele at the TRIB1 locus showed strong tendency toward increased plasma levels of GCA (p=0.02) and GUDCA (p=0.009).	Glycine	107-114	tribbles pseudokinase 1	Homo sapiens	173-178
33421565-9	2021	In contrast, facilitating the function of GluN2C-containing receptors using glycine-site NMDA receptor agonists, D-cycloserine (DCS) or AICP, increased the spontaneous firing frequency of PV neurons in a GluN2C-dependent manner.	Glycine	76-83	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	Mus musculus	42-48
33421565-9	2021	In contrast, facilitating the function of GluN2C-containing receptors using glycine-site NMDA receptor agonists, D-cycloserine (DCS) or AICP, increased the spontaneous firing frequency of PV neurons in a GluN2C-dependent manner.	Glycine	76-83	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	Mus musculus	204-210
33508424-11	2021	Strikingly, suppressed CCT3 shifted intracellular levels of glutamine, beta-alanine, glycine, serin, asparagine and sarcosine, which are employed in energy metabolism.	Glycine	85-92	chaperonin containing TCP1 subunit 3	Homo sapiens	23-27
33658720-4	2021	We find that the inhibitor locks GlyT1 in an inward-open conformation and binds at the intracellular gate of the release pathway, overlapping with the glycine-release site.	Glycine	151-158	solute carrier family 6 member 9	Homo sapiens	33-38
33559459-7	2021	Treatment with Gly and l-Arg resulted in significant amelioration of the DIC-induced alterations although l-Arg produced better amelioration of RBC (29.78%), total protein (10.12%), albumin (9.93%) and MPO (65.01%), compared to the DIC group.	Glycine	15-18	myeloperoxidase	Homo sapiens	202-205
33580145-8	2021	FUS(R495X) uses its C-terminal tandem arginine-glycine-glycine regions, RGG2 and RGG3, to bind the PY-NLS binding site of Kapbeta2 for nuclear localization in cells when arginine methylation is inhibited.	Glycine	47-54	FUS RNA binding protein	Homo sapiens	0-3
33580145-8	2021	FUS(R495X) uses its C-terminal tandem arginine-glycine-glycine regions, RGG2 and RGG3, to bind the PY-NLS binding site of Kapbeta2 for nuclear localization in cells when arginine methylation is inhibited.	Glycine	55-62	FUS RNA binding protein	Homo sapiens	0-3
33269555-1	2021	GLYT1 encephalopathy is a form of glycine encephalopathy caused by disturbance of glycine transport.	Glycine	34-41	solute carrier family 6 member 9	Homo sapiens	0-5
33428810-0	2021	SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function.	Glycine	48-55	solute carrier family 6 (neurotransmitter transporter), member 20B	Mus musculus	0-7
33428810-6	2021	Elevating glycine levels back to normal ranges by antisense oligonucleotide-induced SLC6A20 knockdown, or the competitive GlyT1 antagonist sarcosine, normalized NMDAR currents and repetitive climbing behavior observed in these mice.	Glycine	10-17	solute carrier family 6 (neurotransmitter transporter), member 20B	Mus musculus	84-91
33049473-7	2021	Molecular docking analysis revealed that the Al12N12/Gly (-11.7 kcal/mol) and the Al12ON11/Gly (-9.2 kcal/mol) complexes have a good binding affinity with protein tumor necrosis factor alpha (TNF-alpha).	Glycine	53-56	tumor necrosis factor	Homo sapiens	163-190
33049473-7	2021	Molecular docking analysis revealed that the Al12N12/Gly (-11.7 kcal/mol) and the Al12ON11/Gly (-9.2 kcal/mol) complexes have a good binding affinity with protein tumor necrosis factor alpha (TNF-alpha).	Glycine	53-56	tumor necrosis factor	Homo sapiens	192-201
33049473-7	2021	Molecular docking analysis revealed that the Al12N12/Gly (-11.7 kcal/mol) and the Al12ON11/Gly (-9.2 kcal/mol) complexes have a good binding affinity with protein tumor necrosis factor alpha (TNF-alpha).	Glycine	91-94	tumor necrosis factor	Homo sapiens	163-190
33049473-7	2021	Molecular docking analysis revealed that the Al12N12/Gly (-11.7 kcal/mol) and the Al12ON11/Gly (-9.2 kcal/mol) complexes have a good binding affinity with protein tumor necrosis factor alpha (TNF-alpha).	Glycine	91-94	tumor necrosis factor	Homo sapiens	192-201
33049473-9	2021	These results suggest that the Al12N12/Gly complex in comparison with the Al16N16/Gly, Al12ON11/Gly, and the Al12CN11/Gly complexes could be efficient inhibitors of TNF-alpha.	Glycine	39-42	tumor necrosis factor	Homo sapiens	165-174
33049473-9	2021	These results suggest that the Al12N12/Gly complex in comparison with the Al16N16/Gly, Al12ON11/Gly, and the Al12CN11/Gly complexes could be efficient inhibitors of TNF-alpha.	Glycine	82-85	tumor necrosis factor	Homo sapiens	165-174
33049473-9	2021	These results suggest that the Al12N12/Gly complex in comparison with the Al16N16/Gly, Al12ON11/Gly, and the Al12CN11/Gly complexes could be efficient inhibitors of TNF-alpha.	Glycine	82-85	tumor necrosis factor	Homo sapiens	165-174
33049473-9	2021	These results suggest that the Al12N12/Gly complex in comparison with the Al16N16/Gly, Al12ON11/Gly, and the Al12CN11/Gly complexes could be efficient inhibitors of TNF-alpha.	Glycine	82-85	tumor necrosis factor	Homo sapiens	165-174
33542258-7	2021	Reducing glycine levels rescued timely emergence in glyt1-/- mutants, pointing to a causal role for elevated glycine.	Glycine	9-16	solute carrier family 6 member 9	Homo sapiens	52-57
33269555-1	2021	GLYT1 encephalopathy is a form of glycine encephalopathy caused by disturbance of glycine transport.	Glycine	82-89	solute carrier family 6 member 9	Homo sapiens	0-5
33369211-4	2021	Heterozygous carriers of frameshift/splicing variants in COL4A3/COL4A4 presented a higher risk of developing renal failure than those with missense variants in the glycine domains (p = 0.015).	Glycine	164-171	collagen type IV alpha 4 chain	Homo sapiens	64-70
33508318-8	2021	SMKI-mediated displacement of the Gly-rich loop released C1a and exposed the DAG binding site, enhancing PKCalpha translocation both to synthetic lipid bilayers and to live cell membranes in the presence of DAG.	Glycine	34-37	protein kinase C alpha	Homo sapiens	105-113
33462517-4	2021	Here we show that cholesterol in GP-containing membranes enhances fusion and the membrane-proximal external region and transmembrane (MPER/TM) domain of GP interacts with cholesterol via several glycine residues in the GP2 TM domain, notably G660.	Glycine	195-202	glycoprotein 2	Homo sapiens	219-222
33151007-2	2021	Over sixty TDP-43 mutations have been identified in patients suffering from these two diseases, but most variations are located in the protein"s disordered C-terminal glycine-rich region.	Glycine	167-174	TAR DNA binding protein	Homo sapiens	11-17
33524012-2	2021	Defect in glycine decarboxylase (GLDC) causes Non-ketotic Hyperglycinemia (NKH), a neurological disease associated with elevation of plasma glycine.	Glycine	10-17	glycine decarboxylase	Mus musculus	33-37
32770541-4	2021	COL1A1 and COL1A2 gene variants were identified in 44.23%, of which 28.84% were glycine substitution abnormalities.	Glycine	80-87	collagen type I alpha 2 chain	Homo sapiens	11-17
33484385-0	2022	Regulation of the Glycine Transporter GLYT1 by microRNAs.	Glycine	18-25	solute carrier family 6 member 9	Homo sapiens	38-43
33484385-1	2022	The glycine transporter GLYT1 participates in inhibitory and excitatory neurotransmission by controlling the reuptake of this neuroactive substance from synapses.	Glycine	4-11	solute carrier family 6 member 9	Homo sapiens	24-29
33484385-7	2022	Consistently, these two microRNAs downregulated the uptake of [3H]glycine into glial C6 cells, a cell line where GLYT1 is the main carrier for glycine.	Glycine	66-73	solute carrier family 6 member 9	Homo sapiens	113-118
33484385-7	2022	Consistently, these two microRNAs downregulated the uptake of [3H]glycine into glial C6 cells, a cell line where GLYT1 is the main carrier for glycine.	Glycine	143-150	solute carrier family 6 member 9	Homo sapiens	113-118
33482823-9	2021	Among the 96 malaria-positive samples assayed from day 0, 70.8% (95% CI: 60.8, 79.2) contained the DHPS double (Gly-437 + Glu-540) mutation and 92.7% (95% CI: 85.3, 96.5) had the DHFR triple (Asn-108 + Ile-51 + Arg-59) mutation.	Glycine	112-115	deoxyhypusine synthase	Homo sapiens	99-103
33498551-6	2021	Further, we present a structural mechanism for the susceptibility of the CPR to different redox states based on the flip of a glycine residue disrupting the local interaction network that maintains inter-domain proximity.	Glycine	126-133	cytochrome p450 oxidoreductase	Homo sapiens	73-76
33569080-2	2021	Mutation of AMT or GLDC, encoding the GCS components aminomethyltransferase and glycine decarboxylase, can cause malformations of the developing CNS (neural tube defects (NTDs) and ventriculomegaly) as well as a post-natal life-limiting neurometabolic disorder, Non-Ketotic Hyperglycinemia.	Glycine	80-87	glycine decarboxylase	Mus musculus	19-23
33737018-5	2021	RESULTS: All patients were identified with heterozygous glycine substitutions in COL1A2.	Glycine	56-63	collagen type I alpha 2 chain	Homo sapiens	81-87
33382023-11	2020	Significant decrease in TMPRSS2-Fisetin and TMPRSS2-Nafamostat complex fluctuation occurred around His 41, Glu 44, Gly 136, Ser 186 in RMSF study.	Glycine	115-118	transmembrane serine protease 2	Homo sapiens	24-31
32654243-12	2021	Amino acid supplementation did not appear to ameliorate these effects; however, there were some positive effects of glycine on NF-kappaB and arginine through increased CAT-1.	Glycine	116-123	solute carrier family 7 member 1	Gallus gallus	168-173
33122032-7	2021	Using a therapeutic concentration of zonisamide (100 muM), the potency of glycine was significantly shifted from 106 to 56 muM at alpha1, 185 to 112 muM at alpha2, and 245 to 91 muM at alpha3 receptors.	Glycine	74-81	BCL2 related protein A1	Homo sapiens	130-162
33391421-1	2021	Introduction: Previous studies have shown that peptides containing the asparagine-glycine-arginine (NGR) sequence can specifically bind to CD13 (aminopeptidase N) receptor, a tumor neovascular biomarker that is over-expressed on the surface of angiogenic blood vessels and various tumor cells, and it plays an important role in angiogenesis and tumor progression.	Glycine	82-89	reticulon 4 receptor	Mus musculus	100-103
33523018-10	2021	Gly(2)-GLP-2 furthermore reduced the inflammation response as seen in lower microglia activation, and decreased NLRP3 and interleukin-1beta pro-inflammatory cytokine expression levels.	Glycine	0-3	interleukin 1 beta	Mus musculus	122-139
33599438-8	2021	Genetic analysis demonstrated that the patient had a SLC26A3 c.269_270dupAA homozygous mutation in exon 3, leading to a frameshift from 91st amino acid Gly and alteration of the SLC26A3 transmembrane protein sequence, thus resulting in a Cl-/HCO3- exchange barrier.	Glycine	152-155	solute carrier family 26 member 3	Homo sapiens	53-60
33382023-11	2020	Significant decrease in TMPRSS2-Fisetin and TMPRSS2-Nafamostat complex fluctuation occurred around His 41, Glu 44, Gly 136, Ser 186 in RMSF study.	Glycine	115-118	transmembrane serine protease 2	Homo sapiens	44-51
33323414-5	2020	Whole-genome analysis revealed that a membrane channel protein with glycine zipper motifs is unique to euryhaline Synechococcus The upregulation of this protein, the osmotic sensors, and the heat shock protein HSP20 and the downregulation of the osmolyte biosynthesis enable euryhaline Synechococcus to well adapt to the low and fluctuating salinity in the estuarine environment.	Glycine	68-75	heat shock protein family B (small) member 6	Homo sapiens	210-215
33338404-0	2020	ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.	Glycine	33-40	FUS RNA binding protein	Homo sapiens	29-32
33338404-0	2020	ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.	Glycine	33-40	FUS RNA binding protein	Homo sapiens	117-120
33271013-0	2020	Secondary Chemical Bonding between Insoluble Calcium Oxalate and Carbonyl Oxygen Atoms of GLY and VAL Residues Triggers the Formation of Abeta Aggregates and Their Deposition in the Brain.	Glycine	90-93	amyloid beta precursor protein	Homo sapiens	137-142
32978260-5	2020	Both A2ML1s" thiol esters were reactive towards the amine substrate glycine, but only wildtype A2ML1 reacted with the hydroxyl substrate glycerol, demonstrating that His1084 increases the hydroxyl reactivity of A2ML1"s thiol ester.	Glycine	68-75	alpha-2-macroglobulin like 1	Homo sapiens	5-10
33310850-1	2020	Potassium-chloride cotransporters KCC1 to KCC4 mediate the coupled export of potassium and chloride across the plasma membrane and play important roles in cell volume regulation, auditory system function, and gamma-aminobutyric acid (GABA) and glycine-mediated inhibitory neurotransmission.	Glycine	244-251	solute carrier family 12 member 7	Homo sapiens	42-46
33268508-3	2020	We performed transcriptomics in livers from humans and mice with NAFLD and found suppression of glycine biosynthetic genes, primarily alanine-glyoxylate aminotransferase 1 (AGXT1).	Glycine	96-103	alanine-glyoxylate aminotransferase	Mus musculus	134-171
33268508-3	2020	We performed transcriptomics in livers from humans and mice with NAFLD and found suppression of glycine biosynthetic genes, primarily alanine-glyoxylate aminotransferase 1 (AGXT1).	Glycine	96-103	alanine-glyoxylate aminotransferase	Mus musculus	173-178
33268508-4	2020	Genetic (Agxt1 -/- mice) and dietary approaches to limit glycine availability resulted in exacerbated diet-induced hyperlipidemia and steatohepatitis, with suppressed mitochondrial/peroxisomal fatty acid beta-oxidation (FAO) and enhanced inflammation as the underlying pathways.	Glycine	57-64	alanine-glyoxylate aminotransferase	Mus musculus	9-14
33367225-1	2020	Amyloid precursor protein (APP) cleavage by the beta-secretase produces the C99 transmembrane (TM) protein, which contains three dimerization-inducing Gly-x-x-x-Gly motifs.	Glycine	151-154	amyloid beta precursor protein	Homo sapiens	0-25
33030354-1	2020	Objective: To evaluate insulin treatment satisfaction, safety, and effectiveness of biosimilar insulin glargine (GLY) in real-world clinical practice for Japanese patients with type 2 diabetes mellitus (T2DM) who switched from originator insulin glargine (100 U/mL) or insulin degludec treatment to GLY treatment.Methods: The Insulin Treatment Satisfaction Questionnaire (ITSQ) was used to assess treatment satisfaction in a subgroup analysis of a post-marketing safety study.	Glycine	113-116	insulin	Homo sapiens	95-102
33367225-1	2020	Amyloid precursor protein (APP) cleavage by the beta-secretase produces the C99 transmembrane (TM) protein, which contains three dimerization-inducing Gly-x-x-x-Gly motifs.	Glycine	161-164	amyloid beta precursor protein	Homo sapiens	0-25
33098865-3	2020	Using single molecule FRET investigations, we show that in the presence of calcium-calmodulin the distance across the two GluN1 subunits at the entrance of the first transmembrane segment is shorter, and the bi-lobed cleft of the glycine-binding domain in GluN1 is more closed when bound to glycine and glutamate, relative to what is observed in the presence of barium-calmodulin.	Glycine	230-237	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	122-127
33098865-3	2020	Using single molecule FRET investigations, we show that in the presence of calcium-calmodulin the distance across the two GluN1 subunits at the entrance of the first transmembrane segment is shorter, and the bi-lobed cleft of the glycine-binding domain in GluN1 is more closed when bound to glycine and glutamate, relative to what is observed in the presence of barium-calmodulin.	Glycine	230-237	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	256-261
33098865-3	2020	Using single molecule FRET investigations, we show that in the presence of calcium-calmodulin the distance across the two GluN1 subunits at the entrance of the first transmembrane segment is shorter, and the bi-lobed cleft of the glycine-binding domain in GluN1 is more closed when bound to glycine and glutamate, relative to what is observed in the presence of barium-calmodulin.	Glycine	291-298	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	122-127
33030354-1	2020	Objective: To evaluate insulin treatment satisfaction, safety, and effectiveness of biosimilar insulin glargine (GLY) in real-world clinical practice for Japanese patients with type 2 diabetes mellitus (T2DM) who switched from originator insulin glargine (100 U/mL) or insulin degludec treatment to GLY treatment.Methods: The Insulin Treatment Satisfaction Questionnaire (ITSQ) was used to assess treatment satisfaction in a subgroup analysis of a post-marketing safety study.	Glycine	113-116	insulin	Homo sapiens	95-102
33030354-1	2020	Objective: To evaluate insulin treatment satisfaction, safety, and effectiveness of biosimilar insulin glargine (GLY) in real-world clinical practice for Japanese patients with type 2 diabetes mellitus (T2DM) who switched from originator insulin glargine (100 U/mL) or insulin degludec treatment to GLY treatment.Methods: The Insulin Treatment Satisfaction Questionnaire (ITSQ) was used to assess treatment satisfaction in a subgroup analysis of a post-marketing safety study.	Glycine	113-116	insulin	Homo sapiens	95-102
33266488-8	2020	Among the AA and lipid profiles, SeP inversely correlated with serine (rS = -0.31), glycine (rS = -0.44) and branched chain AA (rS = -0.32), and directly correlated with saturated (rS = 0.41) and monounsaturated FFAs (rS = 0.40).	Glycine	84-91	selenoprotein P	Homo sapiens	33-36
33208462-5	2021	Based on our previous finding that farnesylated DNAJA1 is a crucial chaperone in maintaining mutp53 stabilization, and by using an in silico approach, we built 3-D homology models of human DNAJA1 and mutp53R175H proteins, identified the interacting pocket in the DNAJA1-mutp53R175H complex, and found one critical druggable small molecule binding  site in the DNAJA1 glycine/phenylalanine rich region.	Glycine	367-374	DnaJ heat shock protein family (Hsp40) member A1	Homo sapiens	48-54
33208462-5	2021	Based on our previous finding that farnesylated DNAJA1 is a crucial chaperone in maintaining mutp53 stabilization, and by using an in silico approach, we built 3-D homology models of human DNAJA1 and mutp53R175H proteins, identified the interacting pocket in the DNAJA1-mutp53R175H complex, and found one critical druggable small molecule binding  site in the DNAJA1 glycine/phenylalanine rich region.	Glycine	367-374	DnaJ heat shock protein family (Hsp40) member A1	Homo sapiens	189-195
33208462-5	2021	Based on our previous finding that farnesylated DNAJA1 is a crucial chaperone in maintaining mutp53 stabilization, and by using an in silico approach, we built 3-D homology models of human DNAJA1 and mutp53R175H proteins, identified the interacting pocket in the DNAJA1-mutp53R175H complex, and found one critical druggable small molecule binding  site in the DNAJA1 glycine/phenylalanine rich region.	Glycine	367-374	DnaJ heat shock protein family (Hsp40) member A1	Homo sapiens	189-195
33208462-5	2021	Based on our previous finding that farnesylated DNAJA1 is a crucial chaperone in maintaining mutp53 stabilization, and by using an in silico approach, we built 3-D homology models of human DNAJA1 and mutp53R175H proteins, identified the interacting pocket in the DNAJA1-mutp53R175H complex, and found one critical druggable small molecule binding  site in the DNAJA1 glycine/phenylalanine rich region.	Glycine	367-374	DnaJ heat shock protein family (Hsp40) member A1	Homo sapiens	189-195
33159856-0	2020	ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.	Glycine	33-40	FUS RNA binding protein	Homo sapiens	29-32
33159856-0	2020	ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.	Glycine	33-40	FUS RNA binding protein	Homo sapiens	117-120
33191723-8	2020	Genetic analysis demonstrated that the patient had a SLC26A3 c.269_270dupAA homozygous mutation in exon 3, leading to a frameshift from 91st amino acid Gly and alteration of the SLC26A3 transmembrane protein sequence, thus resulting in a Cl-/HCO3- exchange barrier.	Glycine	152-155	solute carrier family 26 member 3	Homo sapiens	53-60
32341465-8	2020	Farnesoid X receptor (FXR) inhibitor glycine-beta-muricholic acid or FXR knockdown reversed the downregulation of PepT1 expression by CDCA and GW4064 (another FXR agonist).	Glycine	37-44	solute carrier family 15 member 1	Homo sapiens	114-119
33176135-5	2020	In high-fat-fed ZFRs, dietary glycine supplementation raises urinary acyl-glycine content and lowers circulating triglycerides but also results in accumulation of long-chain acyl-coenzyme As (acyl-CoAs), lower 5" adenosine monophosphate-activated protein kinase (AMPK) phosphorylation in muscle, and no improvement in glucose tolerance.	Glycine	30-37	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	213-261
33176135-5	2020	In high-fat-fed ZFRs, dietary glycine supplementation raises urinary acyl-glycine content and lowers circulating triglycerides but also results in accumulation of long-chain acyl-coenzyme As (acyl-CoAs), lower 5" adenosine monophosphate-activated protein kinase (AMPK) phosphorylation in muscle, and no improvement in glucose tolerance.	Glycine	30-37	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	263-267
32743799-3	2020	Mutation of the GCS component glycine decarboxylase (GLDC) in Non-Ketotic Hyperglycinemia (NKH) causes accumulation of glycine in body fluids, but there is a gap in our knowledge regarding the effects on glycine metabolism in tissues.	Glycine	30-37	glycine decarboxylase	Mus musculus	53-57
32915994-6	2020	RNA-seq analysis using the Gly-rich domain-deleted mutant coupled with snRNP70 knockdown revealed that FUS has a potential to regulate gene expression in both snRNP70-dependent and -independent manners through the Gly-rich domain.	Glycine	27-30	FUS RNA binding protein	Homo sapiens	103-106
32743799-3	2020	Mutation of the GCS component glycine decarboxylase (GLDC) in Non-Ketotic Hyperglycinemia (NKH) causes accumulation of glycine in body fluids, but there is a gap in our knowledge regarding the effects on glycine metabolism in tissues.	Glycine	79-86	glycine decarboxylase	Mus musculus	30-51
32743799-3	2020	Mutation of the GCS component glycine decarboxylase (GLDC) in Non-Ketotic Hyperglycinemia (NKH) causes accumulation of glycine in body fluids, but there is a gap in our knowledge regarding the effects on glycine metabolism in tissues.	Glycine	79-86	glycine decarboxylase	Mus musculus	53-57
32743799-4	2020	Here, we analysed mice carrying mutations in Gldc that result in severe or mild elevations of plasma glycine and model NKH.	Glycine	101-108	glycine decarboxylase	Mus musculus	45-49
32743799-5	2020	Liver of Gldc-deficient mice accumulated glycine and numerous glycine derivatives, including multiple acylglycines, indicating increased flux through reactions mediated by enzymes including glycine-N-acyltransferase and arginine:glycine amidinotransferase.	Glycine	41-48	glycine decarboxylase	Mus musculus	9-13
32743799-5	2020	Liver of Gldc-deficient mice accumulated glycine and numerous glycine derivatives, including multiple acylglycines, indicating increased flux through reactions mediated by enzymes including glycine-N-acyltransferase and arginine:glycine amidinotransferase.	Glycine	62-69	glycine decarboxylase	Mus musculus	9-13
32743799-5	2020	Liver of Gldc-deficient mice accumulated glycine and numerous glycine derivatives, including multiple acylglycines, indicating increased flux through reactions mediated by enzymes including glycine-N-acyltransferase and arginine:glycine amidinotransferase.	Glycine	62-69	glycine decarboxylase	Mus musculus	9-13
32743799-8	2020	Elevation of brain tissue glycine occurred even in the presence of only mildly elevated plasma glycine in mice carrying a missense allele of Gldc.	Glycine	26-33	glycine decarboxylase	Mus musculus	141-145
33112230-4	2020	Here, we show that glycine-305 and the homologous site in IFITM3, glycine-95, drive protein oligomerization from within a GxxxG motif.	Glycine	66-73	interferon induced transmembrane protein 3	Homo sapiens	58-64
33122756-3	2020	We found that the S688Y mutation significantly increases the EC50 of both glycine and D-serine in GluN1/GluN2A and GluN1/GluN2B receptors, and significantly slows desensitisation of GluN1/GluN3A receptors.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	98-103
33122756-3	2020	We found that the S688Y mutation significantly increases the EC50 of both glycine and D-serine in GluN1/GluN2A and GluN1/GluN2B receptors, and significantly slows desensitisation of GluN1/GluN3A receptors.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	104-110
33122756-3	2020	We found that the S688Y mutation significantly increases the EC50 of both glycine and D-serine in GluN1/GluN2A and GluN1/GluN2B receptors, and significantly slows desensitisation of GluN1/GluN3A receptors.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	115-120
33122756-3	2020	We found that the S688Y mutation significantly increases the EC50 of both glycine and D-serine in GluN1/GluN2A and GluN1/GluN2B receptors, and significantly slows desensitisation of GluN1/GluN3A receptors.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	115-120
32980057-2	2020	Since the substitution of a single amino acid (Ala to Ser/Gly at position 302) of the Drosophila melanogaster Rdl gene was first identified to confer high level resistance to dieldrin, mutations at the equivalent positions have been reported to confer resistance to dieldrin and/or fipronil in a wide range of different insects.	Glycine	58-61	Resistant to dieldrin	Drosophila melanogaster	110-113
33112230-3	2020	Mutation of proline rich transmembrane protein 2 (PRRT2), a regulator of neurotransmitter release, at glycine-305 was previously linked to paroxysmal neurological disorders in humans.	Glycine	102-109	proline rich transmembrane protein 2	Homo sapiens	12-48
33112230-3	2020	Mutation of proline rich transmembrane protein 2 (PRRT2), a regulator of neurotransmitter release, at glycine-305 was previously linked to paroxysmal neurological disorders in humans.	Glycine	102-109	proline rich transmembrane protein 2	Homo sapiens	50-55
33112230-4	2020	Here, we show that glycine-305 and the homologous site in IFITM3, glycine-95, drive protein oligomerization from within a GxxxG motif.	Glycine	19-26	interferon induced transmembrane protein 3	Homo sapiens	58-64
33112230-5	2020	Mutation of glycine-95 (and to a lesser extent, glycine-91) disrupted IFITM3 oligomerization and reduced its antiviral activity against Influenza A virus.	Glycine	12-19	interferon induced transmembrane protein 3	Homo sapiens	70-76
33112230-5	2020	Mutation of glycine-95 (and to a lesser extent, glycine-91) disrupted IFITM3 oligomerization and reduced its antiviral activity against Influenza A virus.	Glycine	48-55	interferon induced transmembrane protein 3	Homo sapiens	70-76
33112230-6	2020	An oligomerization-defective variant was used to reveal that IFITM3 promotes membrane rigidity in a glycine-95-dependent and amphipathic helix-dependent manner.	Glycine	100-107	interferon induced transmembrane protein 3	Homo sapiens	61-67
33059700-5	2020	RESULTS: Our findings indicated that glycine (an amino acid) inhibited D-gal-induced oxidative stress and significantly upregulated the expression and immunoreactivity of antioxidant proteins (Nrf2 and HO-1) that had been suppressed in the mouse brain.	Glycine	37-44	nuclear factor, erythroid derived 2, like 2	Mus musculus	193-197
33114509-6	2020	One statistically significant single nucleotide polymorphism (SNP), rs55941146, which encodes a missense alteration (Val > Gly) in the APBA3 gene, was identified with OR values for association with POF of 13.33 and 4.628 in the discovery and replication sets, respectively.	Glycine	123-126	POF1B actin binding protein	Homo sapiens	198-201
33059700-5	2020	RESULTS: Our findings indicated that glycine (an amino acid) inhibited D-gal-induced oxidative stress and significantly upregulated the expression and immunoreactivity of antioxidant proteins (Nrf2 and HO-1) that had been suppressed in the mouse brain.	Glycine	37-44	heme oxygenase 1	Mus musculus	202-206
33059700-8	2020	We also found that Gly reversed D-gal-induced neuroapoptosis by significantly reducing the protein expression levels of proapoptotic markers (Bax, cytochrome c, cleaved caspase-3, and cleaved PARP-1) and increasing the protein expression level of the antiapoptotic protein Bcl-2.	Glycine	19-22	B cell leukemia/lymphoma 2	Mus musculus	273-278
33059700-10	2020	Moreover, the addition of Gly alleviated D-gal-mediated neuroinflammation by inhibiting gliosis via attenuation of astrocytosis (GFAP) and microgliosis (Iba-1) in addition to reducing the protein expression levels of various inflammatory cytokines (IL-1betaeta and TNFalpha).	Glycine	26-29	tumor necrosis factor	Mus musculus	265-273
33122997-6	2020	We also compare and contrast the two canonical glycine-rich loop motifs in LRRK2 that anchor the nucleotide: the G-Loop in protein kinases that anchors ATP and the P-Loop in GTPases that anchors GTP.	Glycine	47-54	leucine rich repeat kinase 2	Homo sapiens	75-80
33053340-4	2020	A patient-derived R140Q FMRP point mutation mislocalizes PKA-SPARK activity, whereas deletion of the RNA-binding arginine-glycine-glycine (RGG) box (hFMRP-DeltaRGG) produces fibrillar PKA-SPARK assemblies colocalizing with ribonucleoprotein (RNP) and aggregation (thioflavin T) markers, demonstrating fibrillar partitioning of cytosolic protein aggregates.	Glycine	122-129	fragile X messenger ribonucleoprotein 1	Homo sapiens	149-154
33053340-4	2020	A patient-derived R140Q FMRP point mutation mislocalizes PKA-SPARK activity, whereas deletion of the RNA-binding arginine-glycine-glycine (RGG) box (hFMRP-DeltaRGG) produces fibrillar PKA-SPARK assemblies colocalizing with ribonucleoprotein (RNP) and aggregation (thioflavin T) markers, demonstrating fibrillar partitioning of cytosolic protein aggregates.	Glycine	130-137	fragile X messenger ribonucleoprotein 1	Homo sapiens	149-154
32655010-7	2020	Systemic metabolite and biomarker profiling confirmed that high PTGS2 expression in colorectal tumors is significantly associated with higher concentrations of serum amyloid A (SAA) and glycine, and lower concentrations of sphingomyelin, in colorectal cancer patients.	Glycine	186-193	prostaglandin-endoperoxide synthase 2	Homo sapiens	64-69
33023086-0	2020	Transcriptional Activation of Chac1 and Other Atf4-Target Genes Induced by Extracellular l-Serine Depletion is negated with Glycine Consumption in Hepa1-6 Hepatocarcinoma Cells.	Glycine	124-131	activating transcription factor 4	Mus musculus	46-50
33023086-8	2020	These results led us to conclude that the Atf4-mediated gene expression program is activated by extracellular l-serine depletion in Hepa1-6 cells expressing Phgdh, but is antagonized by the subsequent upregulation of l-serine synthesis, mainly from autonomous glycine consumption.	Glycine	260-267	activating transcription factor 4	Mus musculus	42-46
33057941-9	2020	In contrast, glycine cleavage system H (GCSH) hepatic mRNA expression was downregulated in obese versus lean rats, although there was no change in protein expression.	Glycine	13-20	glycine cleavage system protein H	Rattus norvegicus	40-44
32584658-5	2020	Compared with SCT-II, higher glycine content (337.80 and 339.93 residues/1000 residues) and lower degree of proline hydroxylation (51.81% and 52.52%) were observed in ASC and PSC.	Glycine	29-36	apoptosis-associated speck-like protein containing a CARD	Bos taurus	167-170
32093879-0	2020	An association between glycine and insulin levels is observed in patients with pulmonary tuberculosis and type 2 diabetes.	Glycine	23-30	insulin	Homo sapiens	35-42
32093879-2	2020	In particular, glycine has immunomodulatory properties and is a secretagogue of insulin.	Glycine	15-22	insulin	Homo sapiens	80-87
32093879-4	2020	The aim of this study was to evaluate the association between glycine and insulin plasma levels in patients with pulmonary tuberculosis (PTB) and type 2 diabetes mellitus (DM2).	Glycine	62-69	insulin	Homo sapiens	74-81
32093879-9	2020	A correlation between glycine and insulin levels in the PTB (r = 0.326) and PTB-DM2 (r = 0.318) groups was found.	Glycine	22-29	insulin	Homo sapiens	34-41
32093879-10	2020	CONCLUSION: Our results showed a significant association between glycine and insulin plasma levels in patients with PTB and PTB-DM2, which suggests that the determination of glycine levels could be used as a reference test to evaluate both pathologic conditions.	Glycine	65-72	insulin	Homo sapiens	77-84
32093879-10	2020	CONCLUSION: Our results showed a significant association between glycine and insulin plasma levels in patients with PTB and PTB-DM2, which suggests that the determination of glycine levels could be used as a reference test to evaluate both pathologic conditions.	Glycine	174-181	insulin	Homo sapiens	77-84
32454110-6	2020	The KD values of AChE-DPZ and GLY-AChE-DPZ complexes were estimated to be 1.88 x 10-9 and 2.10 x 10-6, respectively.	Glycine	30-33	acetylcholinesterase (Cartwright blood group)	Homo sapiens	17-21
32454110-6	2020	The KD values of AChE-DPZ and GLY-AChE-DPZ complexes were estimated to be 1.88 x 10-9 and 2.10 x 10-6, respectively.	Glycine	30-33	acetylcholinesterase (Cartwright blood group)	Homo sapiens	34-38
32389749-2	2020	Most native NMDA receptors are tetrameric assemblies of two glycine-binding GluN1 and two glutamate-binding GluN2 subunits.	Glycine	60-67	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	76-81
32712301-2	2020	The extracellular glycine concentration is regulated synergistically by two high affinity, large capacity transporters GlyT1 and GlyT2.	Glycine	18-25	solute carrier family 6 member 9	Homo sapiens	119-124
32389749-3	2020	Co-assembly of the glycine-binding GluN1 with glycine-binding GluN3 subunits (GluN3A-B) creates glycine-activated receptors that possess strikingly different functional and pharmacological properties compared to GluN1/GluN2 NMDA receptors.	Glycine	19-26	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	35-40
32389749-3	2020	Co-assembly of the glycine-binding GluN1 with glycine-binding GluN3 subunits (GluN3A-B) creates glycine-activated receptors that possess strikingly different functional and pharmacological properties compared to GluN1/GluN2 NMDA receptors.	Glycine	19-26	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	212-217
32389749-3	2020	Co-assembly of the glycine-binding GluN1 with glycine-binding GluN3 subunits (GluN3A-B) creates glycine-activated receptors that possess strikingly different functional and pharmacological properties compared to GluN1/GluN2 NMDA receptors.	Glycine	46-53	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	35-40
32389749-3	2020	Co-assembly of the glycine-binding GluN1 with glycine-binding GluN3 subunits (GluN3A-B) creates glycine-activated receptors that possess strikingly different functional and pharmacological properties compared to GluN1/GluN2 NMDA receptors.	Glycine	46-53	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	35-40
32389749-7	2020	Furthermore, we demonstrate that EU1180-438 produces robust inhibition of glycine-activated current responses mediated by native GluN1/GluN3A receptors in hippocampal CA1 pyramidal neurons.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	129-134
33007928-0	2020	Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical Trial.	Glycine	14-21	insulin	Homo sapiens	167-174
32831636-7	2020	Furthermore, Gly inhibited colonic gene expression of interleukin- (IL-) 1beta and promoted IL-10 expression in colitis mice.	Glycine	13-16	interleukin 10	Mus musculus	92-97
32458463-7	2020	Furthermore, the enzymatic performance of 5-aminolevulinic acid synthetase (ALAS), which converts glycine and succinate-CoA to release a molecule of CO2 , has also been distinguished, and the effect of the chaperone GroELS on ALAS enzyme folding was successfully identified in the DEPEND system.	Glycine	98-105	5'-aminolevulinate synthase 1	Homo sapiens	42-74
32458463-7	2020	Furthermore, the enzymatic performance of 5-aminolevulinic acid synthetase (ALAS), which converts glycine and succinate-CoA to release a molecule of CO2 , has also been distinguished, and the effect of the chaperone GroELS on ALAS enzyme folding was successfully identified in the DEPEND system.	Glycine	98-105	5'-aminolevulinate synthase 1	Homo sapiens	76-80
32436225-3	2020	Previous studies have shown that glycine receptors (GlyRs) present in the nAc are potentiated by clinically-relevant concentrations of ethanol, where alpha1 and alpha2 are the predominant subunits expressed.	Glycine	33-40	brain protein 1	Mus musculus	150-156
32859182-13	2020	Mechanistic studies found that the anti-inflammatory activity of GLY was related to the inhibition of pro-inflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and PGE2 and that GLY reduced the expression of COX-2 and NF-kappaB p65 proteins in the throat, attenuated throat injury, and reduced inflammatory exudates.	Glycine	65-68	interleukin 1 alpha	Rattus norvegicus	137-145
32859182-13	2020	Mechanistic studies found that the anti-inflammatory activity of GLY was related to the inhibition of pro-inflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and PGE2 and that GLY reduced the expression of COX-2 and NF-kappaB p65 proteins in the throat, attenuated throat injury, and reduced inflammatory exudates.	Glycine	65-68	interleukin 6	Rattus norvegicus	147-151
32859182-13	2020	Mechanistic studies found that the anti-inflammatory activity of GLY was related to the inhibition of pro-inflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and PGE2 and that GLY reduced the expression of COX-2 and NF-kappaB p65 proteins in the throat, attenuated throat injury, and reduced inflammatory exudates.	Glycine	65-68	tumor necrosis factor	Rattus norvegicus	153-162
32859182-13	2020	Mechanistic studies found that the anti-inflammatory activity of GLY was related to the inhibition of pro-inflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and PGE2 and that GLY reduced the expression of COX-2 and NF-kappaB p65 proteins in the throat, attenuated throat injury, and reduced inflammatory exudates.	Glycine	65-68	synaptotagmin 1	Rattus norvegicus	232-235
32859182-13	2020	Mechanistic studies found that the anti-inflammatory activity of GLY was related to the inhibition of pro-inflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and PGE2 and that GLY reduced the expression of COX-2 and NF-kappaB p65 proteins in the throat, attenuated throat injury, and reduced inflammatory exudates.	Glycine	182-185	synaptotagmin 1	Rattus norvegicus	232-235
32859182-15	2020	CONCLUSIONS: These studies indicated that GLY has beneficial anti-inflammatory effects on CP and that it acts through reducing pro-inflammatory factors such as IL-1beta, IL-6, TNF-alpha, and PGE2, as well as decreasing WBC, NEUT, LYMPH and MONO levels and decreasing the expression of COX-2 and NF-kappaB p65 proteins.	Glycine	42-45	interleukin 1 alpha	Rattus norvegicus	160-168
32859182-15	2020	CONCLUSIONS: These studies indicated that GLY has beneficial anti-inflammatory effects on CP and that it acts through reducing pro-inflammatory factors such as IL-1beta, IL-6, TNF-alpha, and PGE2, as well as decreasing WBC, NEUT, LYMPH and MONO levels and decreasing the expression of COX-2 and NF-kappaB p65 proteins.	Glycine	42-45	interleukin 6	Rattus norvegicus	170-174
32859182-15	2020	CONCLUSIONS: These studies indicated that GLY has beneficial anti-inflammatory effects on CP and that it acts through reducing pro-inflammatory factors such as IL-1beta, IL-6, TNF-alpha, and PGE2, as well as decreasing WBC, NEUT, LYMPH and MONO levels and decreasing the expression of COX-2 and NF-kappaB p65 proteins.	Glycine	42-45	tumor necrosis factor	Rattus norvegicus	176-185
32736679-8	2020	Expressions of VEGF and NOS were consistent with the vascular features induced by glycine and an mTOR inhibitor.	Glycine	82-89	vascular endothelial growth factor A	Homo sapiens	15-19
32736679-9	2020	Our results suggest that PI3K/Akt/mTOR signaling may interact with dose-dependent biphasic effects of exogenous glycine on in vivo angiogenesis.	Glycine	112-119	AKT serine/threonine kinase 1	Homo sapiens	30-33
32736679-9	2020	Our results suggest that PI3K/Akt/mTOR signaling may interact with dose-dependent biphasic effects of exogenous glycine on in vivo angiogenesis.	Glycine	112-119	mechanistic target of rapamycin kinase	Danio rerio	34-38
32736679-10	2020	mTOR signaling is a key target for cancer therapy, thus, the combining mTOR inhibitors with glycine may be a potential approach for controlling angiogenesis.	Glycine	92-99	mechanistic target of rapamycin kinase	Danio rerio	0-4
32527722-5	2020	We also investigated two distantly related very-longchain fatty acyl (VLCFA) desaturases from Arabidopsis, ADS1.2 and ADS1.4, which have Ala and Gly, respectively, in place of the gatekeeping Tyr found in mSCD1.	Glycine	145-148	delta 9 desaturase 1	Arabidopsis thaliana	107-111
32527722-6	2020	Substitution of Tyr for Ala and Gly in ADS1.2 and ADS1.4, respectively, blocked their ability to desaturate VLCFAs.	Glycine	32-35	delta 9 desaturase 1	Arabidopsis thaliana	39-43
33101846-4	2020	Metabolomic studies demonstrate that CSN6 expression leads to serine and glycine production.	Glycine	73-80	COP9 signalosome subunit 6	Homo sapiens	37-41
33101846-7	2020	Thus, these data suggest a link of CSN6-FOXO4 axis and ser/gly metabolism.	Glycine	59-62	COP9 signalosome subunit 6	Homo sapiens	35-39
33101846-9	2020	The results illustrate a pathway regulation of FOXO4-mediated serine/glycine metabolism through the function of CSN6-COP1 axis.	Glycine	69-76	COP9 signalosome subunit 6	Homo sapiens	112-116
33101846-9	2020	The results illustrate a pathway regulation of FOXO4-mediated serine/glycine metabolism through the function of CSN6-COP1 axis.	Glycine	69-76	COP1 E3 ubiquitin ligase	Homo sapiens	117-121
32917219-0	2020	Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-kappabeta pathway.	Glycine	9-16	ADAM metallopeptidase domain 17	Rattus norvegicus	106-112
32736679-0	2020	The role of PI3K/Akt/mTOR signaling in dose-dependent biphasic effects of glycine on vascular development.	Glycine	74-81	AKT serine/threonine kinase 1	Homo sapiens	17-20
32736679-0	2020	The role of PI3K/Akt/mTOR signaling in dose-dependent biphasic effects of glycine on vascular development.	Glycine	74-81	mechanistic target of rapamycin kinase	Homo sapiens	21-25
31987864-7	2020	PTC-174 increases potencies of co-agonists glutamate and glycine by 2- to 5-fold at GluN1/2C and GluN1/2D receptors, and NMDA receptor activation facilitates allosteric modulation by PTC-174.	Glycine	57-64	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	84-89
32185884-1	2020	HLA-DRB1*13:290 differs from HLA-DRB1*13:02:01:01 by a single nucleotide substitution in codon 86 (Gly > Ala).	Glycine	99-102	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-8
32203082-3	2020	N-myristoylation refers to the attachment of 14-carbon fatty acid myristates to the N-terminal glycine of proteins by N-myristoyltransferases (NMT) and affects their physiology such as plasma targeting, subcellular tracking and localization, thereby influencing the function of proteins.	Glycine	95-102	N-myristoyltransferase 1	Homo sapiens	118-141
32203082-3	2020	N-myristoylation refers to the attachment of 14-carbon fatty acid myristates to the N-terminal glycine of proteins by N-myristoyltransferases (NMT) and affects their physiology such as plasma targeting, subcellular tracking and localization, thereby influencing the function of proteins.	Glycine	95-102	N-myristoyltransferase 1	Homo sapiens	143-146
32185884-1	2020	HLA-DRB1*13:290 differs from HLA-DRB1*13:02:01:01 by a single nucleotide substitution in codon 86 (Gly > Ala).	Glycine	99-102	major histocompatibility complex, class II, DR beta 1	Homo sapiens	29-37
32453941-0	2020	NMT as a glycine and lysine myristoyltransferase in cancer, immunity, and infections.	Glycine	9-16	N-myristoyltransferase 1	Homo sapiens	0-3
32626969-3	2020	Autophagy-related gene 4a (ATG4a) cleaves autophagy-related protein 8 (Atg8) near the C terminus, allowing Atg8 to conjugate with phosphatidylethanolamine via the exposed glycine; although this is pivotal in cancer development, no study has yet linked it to eye diseases.	Glycine	171-178	GABA type A receptor associated protein like 1	Homo sapiens	42-69
32626969-3	2020	Autophagy-related gene 4a (ATG4a) cleaves autophagy-related protein 8 (Atg8) near the C terminus, allowing Atg8 to conjugate with phosphatidylethanolamine via the exposed glycine; although this is pivotal in cancer development, no study has yet linked it to eye diseases.	Glycine	171-178	GABA type A receptor associated protein like 1	Homo sapiens	71-75
32626969-3	2020	Autophagy-related gene 4a (ATG4a) cleaves autophagy-related protein 8 (Atg8) near the C terminus, allowing Atg8 to conjugate with phosphatidylethanolamine via the exposed glycine; although this is pivotal in cancer development, no study has yet linked it to eye diseases.	Glycine	171-178	GABA type A receptor associated protein like 1	Homo sapiens	107-111
32610085-2	2020	NMDARs are heterotetramers composed of GluN1 and GluN2 subunits, which bind glycine and glutamate, respectively, to activate their ion channels.	Glycine	76-83	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	39-44
31853946-5	2020	The mutation of rs66612022 (COL1A2:p.Gly328Ser) related to glycine substitution was found in the seven patients.	Glycine	59-66	collagen type I alpha 2 chain	Homo sapiens	28-34
32115853-10	2020	The combination of metabolites and transcripts identified four enriched pathways that were affected by dapagliflozin and associated with eGFR: Glycine Degradation [mitochondrial function]; TCA Cycle II [energy metabolism]; L-carnitine Biosynthesis [energy metabolism] and Superpathway of Citrulline Metabolism [nitric oxide synthase and endothelial function].	Glycine	143-150	epidermal growth factor receptor	Homo sapiens	137-141
32337711-0	2020	Molecular dissection of ALS-linked TDP-43: involvement of the Gly-rich domain in interaction with G-quadruplex mRNA.	Glycine	62-65	TAR DNA binding protein	Homo sapiens	35-41
32337711-3	2020	For the molecular dissection of the TDP-43 and G4-RNA interaction, we analyzed it here in vitro and in cultured cells using a set of ten mutant TDP-43 proteins from familial and sporadic ALS patients as well as using the TDP-43 C-terminal Gly-rich domain alone.	Glycine	239-242	TAR DNA binding protein	Homo sapiens	36-42
32337711-4	2020	Our results altogether indicate the involvement of the Gly-rich region of TDP-43 in the initial recognition and binding of G4-RNA, which then induces tight binding of TDP-43 with target RNAs, supposedly in conjunction with its RNA recognition motifs (RRMs).	Glycine	55-58	TAR DNA binding protein	Homo sapiens	74-80
32337711-4	2020	Our results altogether indicate the involvement of the Gly-rich region of TDP-43 in the initial recognition and binding of G4-RNA, which then induces tight binding of TDP-43 with target RNAs, supposedly in conjunction with its RNA recognition motifs (RRMs).	Glycine	55-58	TAR DNA binding protein	Homo sapiens	167-173
32556284-3	2020	The patient had a homozygous substitution of glycine by aspartate at amino acid residue 412 (Gly412Asp) in the thrombin-binding domain of the thrombomodulin gene (designated thrombomodulin-Nagasaki).	Glycine	45-52	coagulation factor II, thrombin	Homo sapiens	111-119
32581305-5	2020	Glycine (Gly) substituted by arginine (Arg) at position 43 (p.Gly43Arg) in PBK cosegregated with the disease in affected members of this family, but was absent in 180 normal control subjects from the same local population.	Glycine	0-7	PDZ binding kinase	Homo sapiens	75-78
32581305-5	2020	Glycine (Gly) substituted by arginine (Arg) at position 43 (p.Gly43Arg) in PBK cosegregated with the disease in affected members of this family, but was absent in 180 normal control subjects from the same local population.	Glycine	0-3	PDZ binding kinase	Homo sapiens	75-78
32496192-4	2020	The structures of resting and desensitized channels reveal a reentrant loop at the amino terminus of ASIC1 that includes the highly conserved "His-Gly" (HG) motif.	Glycine	147-150	acid sensing ion channel subunit 1	Gallus gallus	101-106
32354853-0	2020	A novel glycine receptor variant with startle disease affects syndapin I and glycinergic inhibition.	Glycine	8-15	protein kinase C and casein kinase substrate in neurons 1	Homo sapiens	62-72
32295908-5	2020	Here, we identify three mutations (3mut), Met302, Leu320, and Pro329, that stabilize the apex of the Env trimer in a prefusion-closed conformation and show antigenically, structurally, and immunogenically that combining 3mut with other approaches (e.g., repair and stabilize and glycine-helix breaking) yields well-behaved clade C-Env trimers capable of boosting the breadth of FP-directed responses.	Glycine	279-286	endogenous retrovirus group W member 1, envelope	Homo sapiens	101-104
32295908-5	2020	Here, we identify three mutations (3mut), Met302, Leu320, and Pro329, that stabilize the apex of the Env trimer in a prefusion-closed conformation and show antigenically, structurally, and immunogenically that combining 3mut with other approaches (e.g., repair and stabilize and glycine-helix breaking) yields well-behaved clade C-Env trimers capable of boosting the breadth of FP-directed responses.	Glycine	279-286	endogenous retrovirus group W member 1, envelope	Homo sapiens	331-334
32459324-7	2020	The lower activity and cooperativity for the substrate PEP, lower activation by glycine and diminished response to malate of the D239A variant suggest that the heterotropic allosteric activation effects of free-PEP are also abolished in this variant.	Glycine	80-87	phosphoenolpyruvate carboxylase 2	Zea mays	211-214
32581708-2	2020	Overexpression of glycine transporter 1 (GlyT1) is proposed as a pathological hallmark in the hippocampus of patients with temporal lobe epilepsy (TLE), and we previously demonstrated in rodent epilepsy models that augmentation of glycine suppressed chronic seizures and altered acute seizure thresholds.	Glycine	18-25	solute carrier family 6 member 9	Homo sapiens	41-46
32350111-7	2020	We demonstrate that unique BMP15 finger residues at this site (Arg-301, Gly-304, His-307, and Met-369) enable potent activation of the SMAD2/3 pathway.	Glycine	72-75	bone morphogenetic protein 15	Homo sapiens	27-32
32930305-3	2020	The high surface area provided by AuNPs and the small size of scFv/VL establish the basis for immobilizing a high amount of the anti-G17-Gly on the surface of the electrode for detecting G17-Gly in human plasma samples.	Glycine	137-140	immunglobulin heavy chain variable region	Homo sapiens	62-66
32930305-3	2020	The high surface area provided by AuNPs and the small size of scFv/VL establish the basis for immobilizing a high amount of the anti-G17-Gly on the surface of the electrode for detecting G17-Gly in human plasma samples.	Glycine	137-140	modulator of VRAC current 1	Homo sapiens	67-69
32382416-5	2020	All clinical parameters showed improvement in the Gly-Tbeta4 and CsA groups (all P<0.05).	Glycine	50-53	transforming growth factor alpha regulated gene 3	Mus musculus	54-60
32499479-1	2020	5"-aminolevulinate synthase (ALAS) catalyzes the first step in heme biosynthesis, generating 5"-aminolevulinate from glycine and succinyl-CoA.	Glycine	117-124	5'-aminolevulinate synthase 1	Homo sapiens	0-27
32499479-1	2020	5"-aminolevulinate synthase (ALAS) catalyzes the first step in heme biosynthesis, generating 5"-aminolevulinate from glycine and succinyl-CoA.	Glycine	117-124	5'-aminolevulinate synthase 1	Homo sapiens	29-33
32382416-6	2020	Significantly increased conjunctival gobleT cells and decreased corneal TUNEL positive cells were observed in the Gly-Tbeta4 and CsA groups.	Glycine	114-117	transforming growth factor alpha regulated gene 3	Mus musculus	118-124
32217768-6	2020	Here, we report that adjusting the number and positioning of fluorine atoms within the fluorophenyl ring of glycine derivatives produces isoform-selective KCNA1 channel openers that are inactive against KCNQ2/3 channels, or even KCNA2, the closest relative of KCNA1.	Glycine	108-115	potassium voltage-gated channel subfamily A member 2	Homo sapiens	229-234
32271092-1	2020	Objective: To evaluate the long-term safety and effectiveness of biosimilar insulin glargine (GLY) in real-world clinical practice.Methods: This prospective, non-interventional, multicenter, observational, post-marketing safety study (PMSS) enrolled Japanese patients with type 1 or 2 diabetes mellitus (T1DM or T2DM) starting GLY therapy, and was required by Japanese Pharmaceutical Affairs Law mandating post-marketing safety surveillance to acquire safety and effectiveness data of biosimilar products.	Glycine	94-97	insulin	Homo sapiens	76-83
32429590-10	2020	The altered serum levels of most amino acids were associated with insulin resistance, while the increase in glutamate and the decrease in glycine levels were strongly associated not only with insulin resistance, but also with altered liver metabolism in patients with liver fibrosis.	Glycine	138-145	insulin	Homo sapiens	192-199
32529876-0	2020	High glycine content in TDP-43: a potential culprit in limbic-predominant age-related TDP-43 encephalopathy.	Glycine	5-12	TAR DNA binding protein	Homo sapiens	24-30
32529876-2	2020	Interestingly, TDP-43 contains 6.0% valine and 13.3% glycine, and the buildup of this protein in the brains of patients with limbic-predominant age-related TDP-43 encephalopathy has dire consequences.	Glycine	53-60	TAR DNA binding protein	Homo sapiens	15-21
32529876-2	2020	Interestingly, TDP-43 contains 6.0% valine and 13.3% glycine, and the buildup of this protein in the brains of patients with limbic-predominant age-related TDP-43 encephalopathy has dire consequences.	Glycine	53-60	TAR DNA binding protein	Homo sapiens	156-162
32321762-5	2020	Liquid chromatography-electrospray ionization MS (LC-ESI-MS) analysis of human PrPC from both biological sources indicated that Gly-229 is the omega site in PrPC to which GPI is attached.	Glycine	128-131	prion protein	Homo sapiens	79-83
32321762-5	2020	Liquid chromatography-electrospray ionization MS (LC-ESI-MS) analysis of human PrPC from both biological sources indicated that Gly-229 is the omega site in PrPC to which GPI is attached.	Glycine	128-131	prion protein	Homo sapiens	157-161
32321762-6	2020	Gly-229 in human PrPC does not correspond to Ser-231, the previously reported omega site of Syrian hamster PrPC We found that approximately 41% and 28% of GPI anchors in human PrPCs from human and mouse knock-in brains, respectively, have N-acetylneuraminic acid in the side-chain.	Glycine	0-3	prion protein	Homo sapiens	17-21
32546967-12	2020	miR-19a-3p and AMPK decreased and increased, respectively, during glycine therapy.	Glycine	66-73	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	15-19
32546967-14	2020	Rescue experiments demonstrated that glycine improved cell apoptosis, inflammatory response and glucose metabolism disorder of ischemic stroke through miR-19a-3p/AMPK/GSK-3beta/HO-1 pathway.	Glycine	37-44	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	162-166
32546967-15	2020	Conclusion: Glycine improves ischemic stroke through miR-19a-3p/AMPK/GSK-3beta/HO-1 pathway.	Glycine	12-19	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	64-68
32477178-9	2020	Glycine concentration in the synaptic cleft is finely tuned by glycine transporters, i.e. GlyT1 and GlyT2, that regulate the neurotransmitter"s reuptake, with the first considered a highly potential target for psychosis therapy.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	90-95
32477466-4	2020	Bioinformatic analyses identified the mevalonate and de novo serine/glycine synthesis pathways as potential targets for apoA-I anti-tumor activity.	Glycine	68-75	apolipoprotein A1	Homo sapiens	120-126
31919642-14	2020	Differentially expressed genes enriched in the signaling pathways including Ras signaling pathway; cytokine receptor interaction; tight junction; MAPK signaling pathway, Glycine, serine and threonine metabolism.	Glycine	170-177	interleukin 18 receptor 1	Homo sapiens	99-116
32209436-3	2020	In this study, we demonstrate that co-administered glycine improves phosphorodiamidate morpholino oligomer (PMO) potency in mdx mice with marked functional improvement and an up to 50-fold increase of dystrophin in abdominal muscles compared to PMO in saline.	Glycine	51-58	dystrophin, muscular dystrophy	Mus musculus	201-211
32355040-6	2020	Crystallographic analysis of the DAPK1-purpurin complex revealed that the formation of a hydrogen-bond network is likely to contribute to the favorable enthalpic changes and that stabilization of the glycine-rich loop may cause less favorable entropic changes.	Glycine	200-207	death associated protein kinase 1	Homo sapiens	33-38
31255351-11	2020	Four of the ten were associated [glycine (inversely), caffeine, 1,7-dimethyluric acid, C52:3 triacylglycerol, (positively)], with C-reactive protein levels.	Glycine	33-40	C-reactive protein	Homo sapiens	130-148
32314017-15	2020	Lysozyme (Lys) was captured by aptamer-modified magnetic sodium alginate (M-Alg-Apt); Glycine (pH = 2) as eluent for Lys.	Glycine	86-93	lysozyme	Homo sapiens	0-8
32101618-10	2020	Compared with the GLY + LPS group, mice in the GLY + BSO + LPS group had lower hepatic activities of catalase, superoxide dismutase, and glutathione peroxidase by 33.5%-48.5%; increased activation of NF-kappaB by 2.3-fold; and impaired nuclear factor (erythroid-derived 2)-like 2 signaling by 38.9%.	Glycine	47-50	catalase	Mus musculus	101-109
32101618-10	2020	Compared with the GLY + LPS group, mice in the GLY + BSO + LPS group had lower hepatic activities of catalase, superoxide dismutase, and glutathione peroxidase by 33.5%-48.5%; increased activation of NF-kappaB by 2.3-fold; and impaired nuclear factor (erythroid-derived 2)-like 2 signaling by 38.9%.	Glycine	47-50	nuclear factor, erythroid derived 2, like 2	Mus musculus	236-279
31967407-6	2020	In particular two proteins, the cellular mRNA deadenylase CCR4 (carbon catabolite repressor 4)-NOT (Negative on TATA) complex subunit 2/9 (CNOT2/9) and the serine hydroxymethyltransferase that catalyzes the reversible interconversions of serine and glycine (SHMT1) were found at dramatic low levels in the thymic epithelia of more malignant subtype, thymic squamous cell carcinoma (TSCC).	Glycine	249-256	CCR4-NOT transcription complex subunit 2	Homo sapiens	139-147
31919735-0	2020	Correction to: Phosphomimetic Mutation of Glycine Transporter GlyT1 C-Terminal PDZ Binding Motif Inhibits its Interactions with PSD95.	Glycine	42-49	solute carrier family 6 member 9	Homo sapiens	62-67
31630411-11	2020	In addition, baseline levels of four amino acids (ie, glutamate, glutamine, threonine, and glycine) and two organic acids (ie, lactate and citric acid) were significantly different in ILK knockdown compared with wild-type HPDLFs.	Glycine	91-98	integrin linked kinase	Homo sapiens	184-187
31630411-13	2020	Among them, four amino acids (ie, glutamate, glutamine, threonine, and glycine) and two organic acids (ie, lactate and citric acid) may be closely linked to ILK.	Glycine	71-78	integrin linked kinase	Homo sapiens	157-160
32232139-6	2020	In previous studies, we began to explore this idea by introducing a deactivating tryptophan-to-glycine mutation in the domain-domain interface of a single-chain variable fragment (scFv), and then restoring activity by adding back indole to fit the designed cavity.	Glycine	95-102	immunglobulin heavy chain variable region	Homo sapiens	180-184
32048268-1	2020	BACKGROUND: N-methyl-D-aspartate (NMDA) receptor is a tetrameric protein complex composed of glycine-linked NR1 subunits and glutamate-linked NR2 subunits.	Glycine	93-100	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	108-111
31932327-8	2020	Both glycine lipid classes were shown to promote TLR2-dependent TNF-alpha release from bone marrow macrophages and both were shown to activate human embryonic kidney (HEK) cells through TLR2 and TLR6, but not TLR1.	Glycine	5-12	toll like receptor 2	Homo sapiens	49-53
31932327-8	2020	Both glycine lipid classes were shown to promote TLR2-dependent TNF-alpha release from bone marrow macrophages and both were shown to activate human embryonic kidney (HEK) cells through TLR2 and TLR6, but not TLR1.	Glycine	5-12	toll like receptor 2	Homo sapiens	186-190
31932327-8	2020	Both glycine lipid classes were shown to promote TLR2-dependent TNF-alpha release from bone marrow macrophages and both were shown to activate human embryonic kidney (HEK) cells through TLR2 and TLR6, but not TLR1.	Glycine	5-12	toll like receptor 6	Homo sapiens	195-199
31932327-8	2020	Both glycine lipid classes were shown to promote TLR2-dependent TNF-alpha release from bone marrow macrophages and both were shown to activate human embryonic kidney (HEK) cells through TLR2 and TLR6, but not TLR1.	Glycine	5-12	tumor necrosis factor	Homo sapiens	64-73
32219097-7	2020	Moreover, LPD mice exhibited decreased concentrations of gamma-aminobutyric acid (GABA), glutamate, glycine, dopamine, norepinephrine, serotonin and aspartate in the brain.	Glycine	100-107	acyl-CoA synthetase bubblegum family member 1	Mus musculus	10-13
31948748-5	2020	The ABCB5/STAT1 high-expressing clones showed higher cellular levels of Ala, Glu, and Asp and lower cellular levels of Phe, Trp, Leu, Ile, Gly, Met, Tyr, Val, and His compared to the ABCB5/STAT1 low-expressing clones.	Glycine	139-142	ATP-binding cassette, sub-family B (MDR/TAP), member 5	Mus musculus	4-9
32062367-11	2020	Our LC-MS and LC-MS/MS studies suggest that the Arg-vasopressin analogs form [(M-H)]+ and [(M-H)+H]+ in the positive ESI mode and undergo in part conversion of their terminal Gly-NH2 (NH2, 16 Da) group to Gly-OH (OH, 17 Da).	Glycine	175-178	arginine vasopressin	Homo sapiens	52-63
32062367-11	2020	Our LC-MS and LC-MS/MS studies suggest that the Arg-vasopressin analogs form [(M-H)]+ and [(M-H)+H]+ in the positive ESI mode and undergo in part conversion of their terminal Gly-NH2 (NH2, 16 Da) group to Gly-OH (OH, 17 Da).	Glycine	205-211	arginine vasopressin	Homo sapiens	52-63
31794058-8	2020	Eight COL1A1/COL1A2 variants were novel and five recurrent with a predominance of glycine substitutions affecting residues within the procollagen N-proteinase cleavage site of alpha1(I) and alpha2(I) procollagens.	Glycine	82-89	collagen type I alpha 2 chain	Homo sapiens	13-19
31794432-1	2020	Ventriculomegaly and hydrocephalus are associated with loss of function of glycine decarboxylase (Gldc) in mice and in humans suffering from non-ketotic hyperglycinemia (NKH), a neurometabolic disorder characterized by accumulation of excess glycine.	Glycine	75-82	glycine decarboxylase	Mus musculus	98-102
31794432-3	2020	Gldc functions in the glycine cleavage system, a mitochondrial component of folate metabolism, whose malfunction results in accumulation of glycine and diminished supply of glycine-derived 1-carbon units to the folate cycle.	Glycine	22-29	glycine decarboxylase	Mus musculus	0-4
31794432-3	2020	Gldc functions in the glycine cleavage system, a mitochondrial component of folate metabolism, whose malfunction results in accumulation of glycine and diminished supply of glycine-derived 1-carbon units to the folate cycle.	Glycine	140-147	glycine decarboxylase	Mus musculus	0-4
31794432-3	2020	Gldc functions in the glycine cleavage system, a mitochondrial component of folate metabolism, whose malfunction results in accumulation of glycine and diminished supply of glycine-derived 1-carbon units to the folate cycle.	Glycine	140-147	glycine decarboxylase	Mus musculus	0-4
31929360-4	2020	METHODS: Sema3A and HIF1alpha were linked together with the three (GGGGS; G, glycine; S, serine) peptide fragment, and their co-expression in iPSC-MSCs was mediated by a lentiviral vector.	Glycine	77-84	hypoxia inducible factor 1 subunit alpha	Homo sapiens	20-29
32111831-1	2020	The promising drug target N-myristoyltransferase (NMT) catalyses an essential protein modification thought to occur exclusively at N-terminal glycines (Gly).	Glycine	152-155	N-myristoyltransferase 1	Homo sapiens	26-48
32111831-1	2020	The promising drug target N-myristoyltransferase (NMT) catalyses an essential protein modification thought to occur exclusively at N-terminal glycines (Gly).	Glycine	152-155	N-myristoyltransferase 1	Homo sapiens	50-53
32110933-0	2020	Glycine Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Regulating NLRP3 Inflammasome and NRF2 Signaling.	Glycine	0-7	nuclear factor, erythroid derived 2, like 2	Mus musculus	101-105
32110933-5	2020	Results showed that glycine pretreatment attenuated LPS-induced decreases of mucin at both protein and mRNA levels, reduced LPS-triggered upregulation of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), interferons, granulocyte-macrophage colony-stimulating factor (GM-CSF), and interleukins.	Glycine	20-27	tumor necrosis factor	Mus musculus	190-217
32110933-5	2020	Results showed that glycine pretreatment attenuated LPS-induced decreases of mucin at both protein and mRNA levels, reduced LPS-triggered upregulation of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), interferons, granulocyte-macrophage colony-stimulating factor (GM-CSF), and interleukins.	Glycine	20-27	tumor necrosis factor	Mus musculus	219-228
32110933-6	2020	Further study showed that glycine-reduced LPS challenge resulted in the upregulation of nuclear factor kappaB (NF-kappaB), nucleotide binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome.	Glycine	26-33	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	111-120
32110933-7	2020	In addition, LPS exposure led to the downregulation of NRF2 and downstream targets, which were significantly improved by glycine administration in the lung tissues.	Glycine	121-128	nuclear factor, erythroid derived 2, like 2	Mus musculus	55-59
32110933-8	2020	Our findings indicated that glycine pretreatment prevented LPS-induced lung injury by regulating both NLRP3 inflammasome and NRF2 signaling.	Glycine	28-35	nuclear factor, erythroid derived 2, like 2	Mus musculus	125-129
33110735-6	2020	The N-terminal LC sequence of FUS is made up of Ser, Tyr, Gly, and Gln, which form a labile cross-beta polymer core while the C-terminal Arg-Gly-Gly repeats accelerate LLPS.	Glycine	58-61	FUS RNA binding protein	Homo sapiens	30-33
32066292-8	2021	GSEA revealed that glycine, serine, threonine and bile acid metabolism may be the underlying mechanism of SPINK1 in HCC.Conclusions: In conclusion, high SPINK1 expression is associated with poor prognosis of HCC.	Glycine	19-26	serine peptidase inhibitor Kazal type 1	Homo sapiens	106-112
32066292-8	2021	GSEA revealed that glycine, serine, threonine and bile acid metabolism may be the underlying mechanism of SPINK1 in HCC.Conclusions: In conclusion, high SPINK1 expression is associated with poor prognosis of HCC.	Glycine	19-26	serine peptidase inhibitor Kazal type 1	Homo sapiens	153-159
32111831-0	2020	High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.	Glycine	120-123	N-myristoyltransferase 1	Homo sapiens	35-57
32111831-1	2020	The promising drug target N-myristoyltransferase (NMT) catalyses an essential protein modification thought to occur exclusively at N-terminal glycines (Gly).	Glycine	142-150	N-myristoyltransferase 1	Homo sapiens	26-48
32111831-1	2020	The promising drug target N-myristoyltransferase (NMT) catalyses an essential protein modification thought to occur exclusively at N-terminal glycines (Gly).	Glycine	142-150	N-myristoyltransferase 1	Homo sapiens	50-53
32041521-6	2020	RESULTS: Based on a list of colour genes of the International Federation of Pigment Cell Societies, a non-synonymous mutation with exchange of a glycine residue at position 291 of the tyrosinase protein by arginine was identified as the cause of dilution of the coat colour.	Glycine	145-152	tyrosinase	Bos taurus	184-194
31388926-0	2020	Kinetic and Thermodynamic Investigation of Human Serum Albumin Interaction with Anticancer Glycine Derivative of Platinum Complex by Using Spectroscopic Methods and Molecular Docking.	Glycine	91-98	albumin	Homo sapiens	55-62
33659783-14	2020	A functional significance of these changes suggests that a wide distribution of the strains with the novel GII.P16 polymerase may be associated both with several amino acid substitutions in the polymerase active center and with the insertion of glutamic acid or glycine in an N-terminal p48 protein that blocks the secretory immunity of intestinal epithelial cells.	Glycine	262-269	cyclin dependent kinase inhibitor 2A	Homo sapiens	111-114
33659783-14	2020	A functional significance of these changes suggests that a wide distribution of the strains with the novel GII.P16 polymerase may be associated both with several amino acid substitutions in the polymerase active center and with the insertion of glutamic acid or glycine in an N-terminal p48 protein that blocks the secretory immunity of intestinal epithelial cells.	Glycine	262-269	interferon regulatory factor 9	Homo sapiens	287-290
31991850-9	2020	We found that LPS/IFN-gamma-induced apoptosis was decreased and the fraction of living cells was increased by glycine.	Glycine	110-117	toll-like receptor 4	Mus musculus	14-17
31991850-9	2020	We found that LPS/IFN-gamma-induced apoptosis was decreased and the fraction of living cells was increased by glycine.	Glycine	110-117	interferon gamma	Mus musculus	18-27
31991850-11	2020	We showed that in BV-2 microglial cells glycine improves viability and counteracts deleterious responses to LPS/IFN-gamma, which might be relevant in neurodegenerative processes associated with inflammation, like Alzheimer"s or Parkinson"s disease.	Glycine	40-47	toll-like receptor 4	Mus musculus	108-111
31991850-11	2020	We showed that in BV-2 microglial cells glycine improves viability and counteracts deleterious responses to LPS/IFN-gamma, which might be relevant in neurodegenerative processes associated with inflammation, like Alzheimer"s or Parkinson"s disease.	Glycine	40-47	interferon gamma	Mus musculus	112-121
31879354-7	2020	The cytoplasmic form of NOC is constitutively expressed and associates externally with membranes of other organelles, including the endoplasmic reticulum, via N-terminal glycine myristoylation.	Glycine	170-177	nocturnin	Homo sapiens	24-27
31780941-13	2019	The ROC analysis implied that the combination of glycine and homogentisic acid could serve as potential biomarkers for the discrimination of control and PSS groups.	Glycine	49-56	PSS	Homo sapiens	153-156
31940043-4	2020	Spinal inhibitory interneurons release GABA, glycine and dynorphin to modulate segmental itch transmission.	Glycine	45-52	itchy E3 ubiquitin protein ligase	Homo sapiens	89-93
30652647-10	2020	Molecular docking studies on EGFR (PDB ID: 1M17) results, the compounds 6d, 6j and 6l showed good dock/PLP scores i.e.-81.28, -73.98 and -75.37 by interacting with Leu-694, Val-702and Gly-772 amino acids via hydrophobic and hydrogen bonds with Asn818 and Met-769.	Glycine	184-187	epidermal growth factor receptor	Homo sapiens	29-33
31370726-0	2020	Lysine methyltransferase SETD6 modifies histones on a glycine-lysine motif.	Glycine	54-61	SET domain containing 6, protein lysine methyltransferase	Homo sapiens	25-30
31955980-6	2020	In line with reported pathogenic mutations in the glycine/phenylalanine (G/F) domain of DNAJB6, both the novel mutations showed reduced anti-aggregation capacity by filter trap assay and TDP-43 disaggregation assays.	Glycine	50-57	TAR DNA binding protein	Homo sapiens	187-193
31856708-13	2019	A glycine to glutamic acid replacement that complies with a bona fide conserved "MLE" sequence within KRAB-A led to a further strong gain in repressor potency to levels comparable to those of the canonical ZNF10 KRAB domain.	Glycine	2-9	zinc finger protein 10	Homo sapiens	206-211
31799558-5	2019	Therefore, we investigate the effect of glycine, alanine, proline and arginine on the stability of a model globular protein bovine serum albumin (BSA) upon thermal and urea-induced unfolding.	Glycine	40-47	albumin	Homo sapiens	131-144
31487503-2	2019	Unlike its homolog KIF13A, KIF13B contains a carboxyl-terminal CAP-Gly domain.	Glycine	67-70	kinesin family member 13B	Mus musculus	27-33
31487503-10	2019	Together, this study provides first evidence that the carboxyl-terminal region of KIF13B containing the CAP-Gly domain is important for the LRP1-DLG1-KIF13B complex formation with implications in the regulation of metabolism, cell polarity, and development.	Glycine	108-111	kinesin family member 13B	Mus musculus	82-88
31487503-10	2019	Together, this study provides first evidence that the carboxyl-terminal region of KIF13B containing the CAP-Gly domain is important for the LRP1-DLG1-KIF13B complex formation with implications in the regulation of metabolism, cell polarity, and development.	Glycine	108-111	kinesin family member 13B	Mus musculus	150-156
31619559-4	2020	The use of either a 15 or 18 amino acid Glycine-Serine linker between the heavy and light chain fragments provided adequate levels of scFv expression.	Glycine	29-54	immunglobulin heavy chain variable region	Homo sapiens	134-138
31881714-6	2019	Other elite status endurance alleles were the Gly allele in PPARGC1A rs8192678 and the C allele PPARD rs2016520.	Glycine	46-49	PPARG coactivator 1 alpha	Homo sapiens	60-68
31908508-8	2019	However, reduced levels of serine, homoserine and allothrionine, substrates for glycine production, indicate the depletion of glycine, thus possibly impair insulin sensitivity in T2D patients of the present study.	Glycine	126-133	insulin	Homo sapiens	156-163
31719558-4	2019	Electrophysiological recordings revealed that GRPR neurons receive local spontaneous excitatory inputs transmitted by glutamate and inhibitory inputs by glycine and GABA, which were transmitted either by separate glycinergic and GABAergic synapses or by glycine and GABA co-releasing synapses.	Glycine	153-160	gastrin releasing peptide receptor	Homo sapiens	46-50
31719558-4	2019	Electrophysiological recordings revealed that GRPR neurons receive local spontaneous excitatory inputs transmitted by glutamate and inhibitory inputs by glycine and GABA, which were transmitted either by separate glycinergic and GABAergic synapses or by glycine and GABA co-releasing synapses.	Glycine	213-220	gastrin releasing peptide receptor	Homo sapiens	46-50
31719558-5	2019	Additionally, all GRPR neurons received both glycine- and GABA-induced tonic currents.	Glycine	45-52	gastrin releasing peptide receptor	Homo sapiens	18-22
31652446-6	2019	We found significant associations between glycine and CPS1 (rs1047883) and PC ae C36:0 and CYP4F2 (rs2108622) variants (P<2.05 x 10-7, after the Bonferroni correction for multiple testing).	Glycine	42-49	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	91-97
30973753-7	2019	Consistent with this, we found that TGF-beta treatment increased cellular levels of glycine and proline in lung fibroblasts.	Glycine	84-91	transforming growth factor beta 1	Homo sapiens	36-44
31612303-3	2019	We have previously demonstrated that glycine, a non-essential amino acid is involved in neuroprotection following intracerebral hemorrhage via the Phosphatase and tensin homolog (PTEN)/protein kinase B (AKT) signaling pathway.	Glycine	37-44	AKT serine/threonine kinase 1	Homo sapiens	203-206
31612303-7	2019	Following a hemorrhagic episode, there is evidence of downregulation of S473 phosphorylation of AKT (p-AKT), and this can be reversed with glycine treatment.	Glycine	139-146	AKT serine/threonine kinase 1	Homo sapiens	96-99
31612303-7	2019	Following a hemorrhagic episode, there is evidence of downregulation of S473 phosphorylation of AKT (p-AKT), and this can be reversed with glycine treatment.	Glycine	139-146	AKT serine/threonine kinase 1	Homo sapiens	103-106
31612303-8	2019	We also found that administration of glycine can reduce neuronal cell death in SAH by activating the AKT pathway.	Glycine	37-44	AKT serine/threonine kinase 1	Homo sapiens	101-104
31612303-9	2019	Glycine was shown to upregulate miRNA-26b, which led to PTEN downregulation followed by AKT activation, resulting in inhibition of neuronal death.	Glycine	0-7	AKT serine/threonine kinase 1	Homo sapiens	88-91
31612303-10	2019	Inhibition of miRNA-26b, PTEN or AKT activation suppressed the neuroprotective effects of glycine.	Glycine	90-97	AKT serine/threonine kinase 1	Homo sapiens	33-36
31612303-12	2019	Taken together, we conclude that glycine has neuroprotective effects in SAH and is mediated by the miRNA-26b/PTEN/AKT signaling pathway, which may be a therapeutic target for treatment of SAH injury.	Glycine	33-40	AKT serine/threonine kinase 1	Homo sapiens	114-117
31165305-3	2019	To date, over 50 dominant mutations were found in TDP-43 in both familial and sporadic ALS patients, most of which were missense mutations in the C-terminal glycine-rich region.	Glycine	157-164	TAR DNA binding protein	Homo sapiens	50-56
31377236-12	2019	Mutational analysis suggested that glycine at 2nd position is essential for AC4 pathogenicity.	Glycine	35-42	adenylate cyclase 4	Homo sapiens	76-79
31176036-3	2019	In this study, we assessed the effects of taurine- or glycine-conjugated cholate, ursodeoxycholate and hyodeoxycholate on the ABCB4-mediated phosphatidylcholine (PC) efflux using Abcb4 knockout mice and HEK293 cells stably expressing ABCB4.	Glycine	54-61	ATP-binding cassette, sub-family B (MDR/TAP), member 4	Mus musculus	126-131
31176036-3	2019	In this study, we assessed the effects of taurine- or glycine-conjugated cholate, ursodeoxycholate and hyodeoxycholate on the ABCB4-mediated phosphatidylcholine (PC) efflux using Abcb4 knockout mice and HEK293 cells stably expressing ABCB4.	Glycine	54-61	ATP-binding cassette, sub-family B (MDR/TAP), member 4	Mus musculus	179-184
31302238-7	2019	This pathological overactivation of NR1/NR2B receptors can be reduced by GlyT-1 inhibitors (NFPS, Org-25935), which decrease excessive glycine release from astroglial cells or by selective antagonists of NR2B subunits (ifenprodil, Ro 25-6981).	Glycine	135-142	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	36-39
31302238-7	2019	This pathological overactivation of NR1/NR2B receptors can be reduced by GlyT-1 inhibitors (NFPS, Org-25935), which decrease excessive glycine release from astroglial cells or by selective antagonists of NR2B subunits (ifenprodil, Ro 25-6981).	Glycine	135-142	solute carrier family 6 member 9	Homo sapiens	73-79
31255973-6	2019	As per the sequence alignment report, two glycine residues (Gly96 and Gly98) were observed in the T3 loop of the beta subunit which get substituted by Asp98 and Ala100 in the T3 loop of the alpha subunit.	Glycine	42-49	immediate early response 3	Homo sapiens	60-65
31515787-6	2019	RESULTS: Three patients were found to carry a c.893G&gt;A mutation in exon 8 of the LBR gene, which resulted in substitution of the 298th amino acid residue glycine by glutamic acid (p.Gly298Glu).	Glycine	157-164	lamin B receptor	Homo sapiens	84-87
31254534-5	2019	Glycine"s effect was blocked by strychnine, a GlyR antagonist, indicating that it was mediated by strychnine-sensitive GlyRs.	Glycine	0-7	glycyl-tRNA synthetase 1	Rattus norvegicus	119-124
31375578-4	2019	Both in vitro and in vivo studies indicated that direct interaction of p17 with hnRNA1 maps within the amino terminus (aa 19-40) of p17 and the Gly-rich region of the C terminus of hnRNP A1.	Glycine	144-147	family with sequence similarity 72 member B	Homo sapiens	71-74
31202607-3	2019	Importantly, GluN1/GluN3A and GluN1/GluN3B receptors form glycine-gated receptors.	Glycine	58-65	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	13-18
31202607-3	2019	Importantly, GluN1/GluN3A and GluN1/GluN3B receptors form glycine-gated receptors.	Glycine	58-65	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	30-35
31173968-2	2019	This regulation is based on inhibition of translation of the virally-encoded EBNA1 mRNA, and involves the interaction of host protein nucleolin (NCL) with G-quadruplex (G4) structures that form in the glycine-alanine repeat (GAr)-encoding sequence of the EBNA1 mRNA.	Glycine	201-208	EBNA-1	Human gammaherpesvirus 4	77-82
31173968-2	2019	This regulation is based on inhibition of translation of the virally-encoded EBNA1 mRNA, and involves the interaction of host protein nucleolin (NCL) with G-quadruplex (G4) structures that form in the glycine-alanine repeat (GAr)-encoding sequence of the EBNA1 mRNA.	Glycine	201-208	EBNA-1	Human gammaherpesvirus 4	255-260
31506484-0	2019	Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.	Glycine	0-7	dystrophin, muscular dystrophy	Mus musculus	94-104
31506484-0	2019	Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.	Glycine	0-7	utrophin	Mus musculus	105-113
33455163-4	2019	In this study, we uncover the interaction between an angiopoietin-1 mimetic peptide, QHREDGS (glutamine-histidine-arginine-glutamic acid-aspartic acid-glycine-serine), immobilized to a collagen-chitosan hydrogel, and murine bone marrow derived macrophages.	Glycine	151-158	angiopoietin 1	Mus musculus	53-67
31498521-4	2019	We found that gly-LDL upregulated ASPN expression.	Glycine	14-17	asporin	Mus musculus	34-38
32003208-12	2019	Hypertensive patients with Arg/Arg and Gly/Arg genotypes had significantly higher HOMA-IR (p <0.01), glucose, insulin and triglycerides levels (p <0.05), than in Gly/Gly genotype.	Glycine	39-42	insulin	Homo sapiens	110-117
31104335-8	2019	Follow-up analyses suggested that glycine mediates the relationship between carbamoyl-phosphate synthase 1 and measures of cardiovascular and diabetes risk, including body mass index, waist-hip ratio, inflammation, and insulin resistance.	Glycine	34-41	insulin	Homo sapiens	219-226
31084501-10	2019	Emerging and vanishing peak absorbance related to OCN- and CO bands was observed in 2230-2100 cm-1 during the radiolysis at 40 K and 80 K. The same new IR bands appear in the range of 1600-1500, 1480-1370, and 1350-1200 cm-1 after total glycine depletion for all temperature configurations.	Glycine	237-244	bone gamma-carboxyglutamate protein	Homo sapiens	50-53
30985039-6	2019	Gan-Lu-Yin (GLY) was the most commonly prescribed CHM, and it reduced cell viability, inhibited tumor proliferation, and induced apoptosis through the poly (ADP-ribose) polymerase and caspase-3-dependent pathway in human NPC TW01 cells.	Glycine	12-15	poly(ADP-ribose) polymerase 1	Homo sapiens	151-179
30985039-6	2019	Gan-Lu-Yin (GLY) was the most commonly prescribed CHM, and it reduced cell viability, inhibited tumor proliferation, and induced apoptosis through the poly (ADP-ribose) polymerase and caspase-3-dependent pathway in human NPC TW01 cells.	Glycine	12-15	caspase 3	Homo sapiens	184-193
30825261-0	2019	Glycine increases glyoxalase-1 function by promoting nuclear factor erythroid 2-related factor 2 translocation into the nucleus of kidney cells of streptozotocin-induced diabetic rats.	Glycine	0-7	glyoxalase 1	Rattus norvegicus	18-30
30825261-0	2019	Glycine increases glyoxalase-1 function by promoting nuclear factor erythroid 2-related factor 2 translocation into the nucleus of kidney cells of streptozotocin-induced diabetic rats.	Glycine	0-7	NFE2 like bZIP transcription factor 2	Rattus norvegicus	53-96
30825261-7	2019	After glycine treatment, these parameters of Glo1 function were markedly increased.	Glycine	6-13	glyoxalase 1	Rattus norvegicus	45-49
30825261-8	2019	Compared with the control group, the levels of Nrf2 mRNA and protein in the total kidney lysis were both markedly elevated in the diabetic group and glycine-treated group.	Glycine	149-156	NFE2 like bZIP transcription factor 2	Rattus norvegicus	47-51
30825261-9	2019	However, the nuclear translocation of Nrf2 was significantly increased in the glycine-treated group than in the diabetic group.	Glycine	78-85	NFE2 like bZIP transcription factor 2	Rattus norvegicus	38-42
30825261-10	2019	In addition, the anti-oxidant capacity and the expressions of other downstream molecules of the Nrf2 signaling pathway were significantly increased after glycine treatment.	Glycine	154-161	NFE2 like bZIP transcription factor 2	Rattus norvegicus	96-100
30825261-11	2019	CONCLUSIONS: The present study shows that glycine might enhance the function of Glo1 and restore anti-oxidant defense by promoting the nuclear translocation of Nrf2, thus inhibiting advanced glycation end-products formation and protecting against renal oxidative stress.	Glycine	42-49	glyoxalase 1	Rattus norvegicus	80-84
30825261-11	2019	CONCLUSIONS: The present study shows that glycine might enhance the function of Glo1 and restore anti-oxidant defense by promoting the nuclear translocation of Nrf2, thus inhibiting advanced glycation end-products formation and protecting against renal oxidative stress.	Glycine	42-49	NFE2 like bZIP transcription factor 2	Rattus norvegicus	160-164
31497683-1	2019	N-Myristoyltransferase (NMT) is a cytosolic monomeric enzyme involved in the allocation of the myristoyl group to the aminoterminal of glycine in several viral and eukaryotic cellular proteins.	Glycine	135-142	N-myristoyltransferase 1	Homo sapiens	0-22
31444392-0	2019	Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors.	Glycine	27-34	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	56-61
31444392-3	2019	Here, we examined the surface delivery and functional properties of NMDARs containing mutations in the glycine-binding sites in GluN1 and GluN3A subunits expressed in mammalian cell lines and primary rat hippocampal neurons.	Glycine	103-110	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	128-133
31497683-1	2019	N-Myristoyltransferase (NMT) is a cytosolic monomeric enzyme involved in the allocation of the myristoyl group to the aminoterminal of glycine in several viral and eukaryotic cellular proteins.	Glycine	135-142	N-myristoyltransferase 1	Homo sapiens	24-27
31311868-3	2019	An X-ray structure of active 2P-ERK2 complexed with AMP-PNP reveals a shift in the Gly-rich loop along with domain closure to position the nucleotide in a more catalytically productive conformation relative to inactive 0P-ERK2:ATP.	Glycine	83-86	mitogen-activated protein kinase 1	Homo sapiens	32-36
31366981-7	2019	Further analysis of the highly similar Cr-AGO2 and Cr-AGO 3 sequences (90% amino acid identity) revealed a glycine-arginine rich N-terminal extension of ~100 amino acids that, given previous work on unicellular protists, may associate AGO with the translation machinery.	Glycine	107-114	uncharacterized protein	Chlamydomonas reinhardtii	54-59
31395095-6	2019	Crucially, filtering of data to focus analysis on peptides potentially bearing glycine for glyphosate replacement revealed that the TMT reporter intensity pattern of all candidates showed conclusively that they are all false discoveries, with none displaying the expected TMT pattern for such a substitution.	Glycine	79-86	tryptase gamma 1	Homo sapiens	132-135
31270129-8	2019	Kinetic modeling showed that the kinetics of GlyT1 are ideally suited for supplying the extracellular glycine levels required for NMDA receptor activation.	Glycine	102-109	solute carrier family 6 member 9	Homo sapiens	45-50
31181988-2	2019	An anti-IL-17 single-chain variable fragment (scFv) derived from ixekizumab (Taltz ) was fused via a glycine-rich linker to anti-BAFF tabalumab.	Glycine	101-108	immunglobulin heavy chain variable region	Homo sapiens	46-50
31273098-4	2019	N-terminal glycine degrons are depleted at native N-termini but strongly enriched at caspase cleavage sites, suggesting roles for the substrate adaptors ZYG11B and ZER1 in protein degradation during apoptosis.	Glycine	11-18	zyg-11 related cell cycle regulator	Homo sapiens	164-168
31080074-1	2019	The attachment of myristate to the N-terminal glycine of certain proteins is largely a co-translational modification catalyzed by N-myristoyltransferase (NMT), and involved in protein membrane-localization.	Glycine	46-53	N-myristoyltransferase 1	Homo sapiens	154-157
31636949-7	2019	The observed class-selectivity of SIRT3 is due to an entropically unfavorable barrier associated with the glycine-flanking motif that the histone Kbhb resides in.	Glycine	106-113	sirtuin 3	Homo sapiens	34-39
31273098-5	2019	Furthermore, ZYG11B and ZER1 were found to participate in the quality control of N-myristoylated proteins, in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation.	Glycine	127-134	zyg-11 related cell cycle regulator	Homo sapiens	24-28
30964837-0	2019	SHMT2 Promotes Liver Regeneration Through Glycine-activated Akt/mTOR Pathway.	Glycine	42-49	AKT serine/threonine kinase 1	Homo sapiens	60-63
30964837-4	2019	Glycine affects the activity of mammalian target of rapamycin (mTOR), which is important for cellular growth and proliferation.	Glycine	0-7	mechanistic target of rapamycin kinase	Homo sapiens	32-61
30964837-0	2019	SHMT2 Promotes Liver Regeneration Through Glycine-activated Akt/mTOR Pathway.	Glycine	42-49	mechanistic target of rapamycin kinase	Homo sapiens	64-68
30964837-4	2019	Glycine affects the activity of mammalian target of rapamycin (mTOR), which is important for cellular growth and proliferation.	Glycine	0-7	mechanistic target of rapamycin kinase	Homo sapiens	63-67
31160332-13	2019	We found that strong facilitation of tonic activity of GluN2C subtype of NMDA receptors using AICP, a newly identified glycine-site agonist of NMDA receptors, modulates the function of reticular thalamus neurons.	Glycine	119-126	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	Mus musculus	55-61
30964837-12	2019	CONCLUSIONS: SHMT2 can contribute to liver regeneration after PH, and this is likely related to the activation of Akt/mTOR signaling pathway by its metabolic product, glycine, in hepatocytes.	Glycine	167-174	AKT serine/threonine kinase 1	Homo sapiens	114-117
30964837-12	2019	CONCLUSIONS: SHMT2 can contribute to liver regeneration after PH, and this is likely related to the activation of Akt/mTOR signaling pathway by its metabolic product, glycine, in hepatocytes.	Glycine	167-174	mechanistic target of rapamycin kinase	Homo sapiens	118-122
31316659-10	2019	The highest effective dose of foods rich in CYP2E1 enzymes such as beef liver, beef brain, and salmon was 239.61 g, 745.45 g, and 203.3 g. Also, foods rich in glycines such as seaweed, tuna, and spinach were 432.98 mg, 934.41 mg, and 2070.71 mg.	Glycine	159-167	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	44-50
31113850-0	2019	mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-beta1-induced collagen biosynthesis.	Glycine	77-84	transforming growth factor beta 1	Homo sapiens	92-101
29737046-4	2019	The RCP used here is based on the alpha-1 sequence of human collagen type I and contains 12 Arg-Gly-Asp motifs.	Glycine	96-99	BCL2 related protein A1	Homo sapiens	34-41
31113850-0	2019	mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-beta1-induced collagen biosynthesis.	Glycine	51-58	transforming growth factor beta 1	Homo sapiens	92-101
31113850-4	2019	Here, we showed that transforming growth factor-beta1 (TGF-beta1), the key pro-fibrotic cytokine implicated in multiple fibrotic conditions, increased the production of activating transcription factor 4 (ATF4), the transcriptional master regulator of amino acid metabolism, to supply glucose-derived glycine to meet the amino acid requirements associated with enhanced collagen production in response to myofibroblast differentiation.	Glycine	300-307	transforming growth factor beta 1	Homo sapiens	21-53
31113850-4	2019	Here, we showed that transforming growth factor-beta1 (TGF-beta1), the key pro-fibrotic cytokine implicated in multiple fibrotic conditions, increased the production of activating transcription factor 4 (ATF4), the transcriptional master regulator of amino acid metabolism, to supply glucose-derived glycine to meet the amino acid requirements associated with enhanced collagen production in response to myofibroblast differentiation.	Glycine	300-307	transforming growth factor beta 1	Homo sapiens	55-64
31089170-0	2019	Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge.	Glycine	60-67	Fc gamma receptor and transporter	Homo sapiens	8-12
30802707-5	2019	Molecular modeling revealed that the compound 4d binds through hydrophobic-hydrophobic interactions with the essential amino acids (LEU: 57, GLY: 58, ILE: 61, and HIS: 96) in the p53-binding cleft, as a standard p53-MDM2 inhibitor (6SJ).	Glycine	141-144	tumor protein p53	Homo sapiens	179-182
30900779-1	2019	This study was conducted to analyse the effects of leucine (Leu) and glycine (Gly)-Leu peptide on expressions of key signalling molecules in mTOR pathway of skeletal muscle satellite cells in neonatal chicks.	Glycine	69-76	mechanistic target of rapamycin kinase	Homo sapiens	141-145
30900779-1	2019	This study was conducted to analyse the effects of leucine (Leu) and glycine (Gly)-Leu peptide on expressions of key signalling molecules in mTOR pathway of skeletal muscle satellite cells in neonatal chicks.	Glycine	78-81	mechanistic target of rapamycin kinase	Homo sapiens	141-145
31118638-2	2019	Glycine transporter 1, encoded by SLC6A9, is responsible for maintaining a low concentration of the N-methyl-D-aspartate receptor (NMDAR) co-agonist - glycine in the synaptic cleft, suggesting its participation in the development of the NMDARs hypofunction described in schizophrenia.	Glycine	151-158	solute carrier family 6 member 9	Homo sapiens	0-21
30770653-2	2019	In this study, a vascular endothelial growth factor (VEGF165) and angiopoietin-1 (Ang-1) dual gene coexpression vector that encoded green fluorescent protein (GFP) was constructed from an arginine-glycine-aspartic acid-modified adenovirus.	Glycine	197-204	vascular endothelial growth factor A	Homo sapiens	17-51
31118638-2	2019	Glycine transporter 1, encoded by SLC6A9, is responsible for maintaining a low concentration of the N-methyl-D-aspartate receptor (NMDAR) co-agonist - glycine in the synaptic cleft, suggesting its participation in the development of the NMDARs hypofunction described in schizophrenia.	Glycine	151-158	solute carrier family 6 member 9	Homo sapiens	34-40
30848915-6	2019	Lys41 is found to guide phosphate transfer through the interactions with the beta-,gamma-, and gamma-phosphate oxygen atoms of adenosine 5"-triphosphate surrounded by two highly conserved glycine residues (Gly44 and Gly76), while Arg98 helps to position the NAG substrate in the catalytic site, which facilitates the phosphate transfer.	Glycine	188-195	N-acetyl-alpha-glucosaminidase	Homo sapiens	258-261
30604098-2	2019	All insulin superfamily members contain three absolutely conserved disulfide linkages and a nonchiral Gly residue immediately following the first B-chain cysteine.	Glycine	102-105	insulin	Homo sapiens	4-11
30940768-7	2019	Through in vitro methylation assays, we validated a set of PRMT5 targets identified by mass spectrometry and provided previously unknown mechanistic insights into the preference of the enzyme to methylate arginine sandwiched between two neighboring glycines (a Gly-Arg-Gly, or "GRG," sequence).	Glycine	249-257	protein arginine methyltransferase 5	Homo sapiens	59-64
30604098-8	2019	The present study revealed functionality of the conserved B-chain Gly residue for a relaxin family peptide for the first time, providing an overview of its contribution to foldability and activity of the insulin superfamily.	Glycine	66-69	insulin	Homo sapiens	204-211
30604098-3	2019	The functionality of this conserved Gly residue in the insulin family has been studied by replacing it with natural L-amino acids or the corresponding unnatural D-amino acids.	Glycine	36-39	insulin	Homo sapiens	55-62
30746902-2	2019	Our results showed that gly-HDL caused macrophage apoptosis with concomitant activation of ER stress pathway, including nuclear translocation of activating transcription factor 6, phosphorylation of protein kinase-like ER kinase (PERK) and eukaryotic translation initiation factor 2alpha, and CHOP up-regulation, which were inhibited by 4-phenylbutyric acid (PBA, an ER stress inhibitor) and the gene silencing of PERK and CHOP.	Glycine	24-27	DNA damage inducible transcript 3	Homo sapiens	293-297
30847846-3	2019	These short, linear segments, known as tankyrase-binding motifs (TBMs), contain some highly conserved features: an arginine at position 1, which occupies a predominantly acidic binding site, and a glycine at position 6 that is sandwiched between two aromatic side chains on the surface of the ARC domain.	Glycine	197-204	tankyrase	Homo sapiens	39-48
30746902-7	2019	These data indicate that gly-HDL may induce macrophage apoptosis through activating ER stress-CHOP pathway and ER stress mediates gly-HDL-induced autophagy, which in turn protects macrophages against apoptosis by alleviating CHOP pathway.	Glycine	25-28	DNA damage inducible transcript 3	Homo sapiens	94-98
30746902-7	2019	These data indicate that gly-HDL may induce macrophage apoptosis through activating ER stress-CHOP pathway and ER stress mediates gly-HDL-induced autophagy, which in turn protects macrophages against apoptosis by alleviating CHOP pathway.	Glycine	25-28	DNA damage inducible transcript 3	Homo sapiens	225-229
30746902-7	2019	These data indicate that gly-HDL may induce macrophage apoptosis through activating ER stress-CHOP pathway and ER stress mediates gly-HDL-induced autophagy, which in turn protects macrophages against apoptosis by alleviating CHOP pathway.	Glycine	130-133	DNA damage inducible transcript 3	Homo sapiens	225-229
30746902-2	2019	Our results showed that gly-HDL caused macrophage apoptosis with concomitant activation of ER stress pathway, including nuclear translocation of activating transcription factor 6, phosphorylation of protein kinase-like ER kinase (PERK) and eukaryotic translation initiation factor 2alpha, and CHOP up-regulation, which were inhibited by 4-phenylbutyric acid (PBA, an ER stress inhibitor) and the gene silencing of PERK and CHOP.	Glycine	24-27	DNA damage inducible transcript 3	Homo sapiens	423-427
30746902-5	2019	Gly-HDL-induced apoptosis, PERK phosphorylation and CHOP up-regulation were suppressed by rapamycin (an autophagy inducer), whereas aggravated by 3-methyladenine (an autophagy inhibitor) and beclin-1 siRNA.	Glycine	0-3	DNA damage inducible transcript 3	Homo sapiens	52-56
30960527-2	2019	l-tryptophan/glycine copolymers, M-G-l-Trp5, M-G-l-Trp10, M-G-l-Trp20 and M-G-l-Trp40, were prepared from l-tryptophan/glycine mixtures.	Glycine	13-20	transient receptor potential cation channel subfamily C member 5	Homo sapiens	39-43
30676254-2	2019	Loss of alanine glyoxylate aminotransferase (AGT) function to convert intermediate metabolite glyoxylate to glycine causes the accumulation and reduction of glyoxylate to glycolate, which eventually is oxidized to oxalate.	Glycine	108-115	alanine-glyoxylate aminotransferase	Mus musculus	8-43
30676254-2	2019	Loss of alanine glyoxylate aminotransferase (AGT) function to convert intermediate metabolite glyoxylate to glycine causes the accumulation and reduction of glyoxylate to glycolate, which eventually is oxidized to oxalate.	Glycine	108-115	alanine-glyoxylate aminotransferase	Mus musculus	45-48
30676254-6	2019	mRNA encoding AGT has the potential to restore normal glyoxylate to glycine metabolism, thus preventing the buildup of calcium oxalate in various organs.	Glycine	68-75	alanine-glyoxylate aminotransferase	Mus musculus	14-17
30988637-8	2019	Conclusion: The effect of FABP2 Ala54Thr polymorphism on response to blood lipids and gly-cemic control in low-GI diets is associated with gender among Han Chinese patients with T2DM.	Glycine	86-89	fatty acid binding protein 2	Homo sapiens	26-31
30242962-2	2019	At low concentrations of endogenous agonists (glycine/D-serine), NYX-2925 partially activates NMDARs, modulating neural pathways relevant for chronic pain.	Glycine	46-53	nyctalopin	Homo sapiens	65-68
31193991-8	2019	Exome sequencing identified a novel de novo heterozygous glycine substitution, c.3296G &gt; A, p.Gly1099Glu, in exon 49 of COL1A2.	Glycine	57-64	collagen type I alpha 2 chain	Homo sapiens	123-129
31193991-11	2019	Here, we demonstrate that the novel glycine substitution in the carboxyl region of alpha2(I) collagen triple helix leads to OI/EDS with brachydactyly and severe tooth defects, expanding the genotypic and phenotypic spectra of OI/EDS overlap syndrome.	Glycine	36-43	collagen type I alpha 2 chain	Homo sapiens	83-101
30483907-0	2019	Glycine supplementation to breast-fed piglets attenuates post-weaning jejunal epithelial apoptosis: a functional role of CHOP signaling.	Glycine	0-7	DNA damage inducible transcript 3	Homo sapiens	121-125
30483907-1	2019	This study was conducted to test the hypothesis that preweaning  glycine supplementation to breast-fed piglets alleviated the post-weaning  apoptosis of jejunal epithelium through CHOP signaling.	Glycine	65-72	DNA damage inducible transcript 3	Homo sapiens	180-184
30483907-7	2019	Western blot analysis showed that 100-200% glycine enhanced the protein levels of occludin, claudin-1, and zonula occludens (ZO)-1 without affecting those of claudin-3, ZO-2, and ZO-3.	Glycine	43-50	tight junction protein 1	Homo sapiens	107-130
30483907-8	2019	Further studies showed that protein abundances of glucose-regulated protein 78 (BiP/GRP78) and p-IRE1alpha, instead of ATF6alpha, were reduced by glycine.	Glycine	146-153	heat shock protein family A (Hsp70) member 5	Homo sapiens	80-83
30483907-8	2019	Further studies showed that protein abundances of glucose-regulated protein 78 (BiP/GRP78) and p-IRE1alpha, instead of ATF6alpha, were reduced by glycine.	Glycine	146-153	heat shock protein family A (Hsp70) member 5	Homo sapiens	84-89
30483907-9	2019	Among the proteins related to apoptosis, abundances of CHOP and p53 were reduced, whereas those of Bcl-2 and Bcl-xL were enhanced in the jejunum of 100-200% glycine-supplemented piglets.	Glycine	157-164	DNA damage inducible transcript 3	Homo sapiens	55-59
30483907-9	2019	Among the proteins related to apoptosis, abundances of CHOP and p53 were reduced, whereas those of Bcl-2 and Bcl-xL were enhanced in the jejunum of 100-200% glycine-supplemented piglets.	Glycine	157-164	tumor protein p53	Homo sapiens	64-67
30483907-9	2019	Among the proteins related to apoptosis, abundances of CHOP and p53 were reduced, whereas those of Bcl-2 and Bcl-xL were enhanced in the jejunum of 100-200% glycine-supplemented piglets.	Glycine	157-164	BCL2 apoptosis regulator	Homo sapiens	99-104
30483907-9	2019	Among the proteins related to apoptosis, abundances of CHOP and p53 were reduced, whereas those of Bcl-2 and Bcl-xL were enhanced in the jejunum of 100-200% glycine-supplemented piglets.	Glycine	157-164	BCL2 like 1	Homo sapiens	109-115
30483907-11	2019	The beneficial effect of glycine was associated with improved intestinal mucosal barrier and reduced apoptosis of enterocytes through CHOP signaling.	Glycine	25-32	DNA damage inducible transcript 3	Homo sapiens	134-138
30710045-9	2019	The activation of AKT mediates the inhibition of NF-kappaB p65/Hif-1alpha signaling by glycine.	Glycine	87-94	thymoma viral proto-oncogene 1	Mus musculus	18-21
30710045-10	2019	Moreover, we confirm that glycine-regulated AKT activation is mediated by the inhibition of PTEN in a PTEN depletion cell line, U251 cells.	Glycine	26-33	AKT serine/threonine kinase 1	Homo sapiens	44-47
30837465-6	2019	Our findings strengthen evidence for a protective effect of glycine on CHD and show that the glycine-T2D association may be driven by a glycine-lowering effect of insulin resistance.	Glycine	93-100	insulin	Homo sapiens	163-170
30837465-6	2019	Our findings strengthen evidence for a protective effect of glycine on CHD and show that the glycine-T2D association may be driven by a glycine-lowering effect of insulin resistance.	Glycine	93-100	insulin	Homo sapiens	163-170
30944692-0	2019	Glycine Suppresses AGE/RAGE Signaling Pathway and Subsequent Oxidative Stress by Restoring Glo1 Function in the Aorta of Diabetic Rats and in HUVECs.	Glycine	0-7	glyoxalase 1	Rattus norvegicus	91-95
30944692-7	2019	The AGE/RAGE signaling pathway in the aorta of diabetic rats was significantly attenuated by glycine treatment as manifested by decreases in levels of AGEs, RAGE, Nox4, and NF-kappaB p65.	Glycine	93-100	synaptotagmin 1	Rattus norvegicus	183-186
30944692-8	2019	The suppressive effect of glycine on the formation of AGEs was associated with increased activity and expression of aortic glyoxalase-1 (Glo1), a crucial enzyme that degrades methylglyoxal (MG), the major precursor of AGEs.	Glycine	26-33	glyoxalase 1	Rattus norvegicus	123-135
30944692-8	2019	The suppressive effect of glycine on the formation of AGEs was associated with increased activity and expression of aortic glyoxalase-1 (Glo1), a crucial enzyme that degrades methylglyoxal (MG), the major precursor of AGEs.	Glycine	26-33	glyoxalase 1	Rattus norvegicus	137-141
30944692-9	2019	In MG-treated HUVECs, glycine restored the function of Glo1, suppressed the AGE/RAGE signaling pathway, and inhibited the generation of reactive oxygen species.	Glycine	22-29	glyoxalase 1	Rattus norvegicus	55-59
30944692-10	2019	In addition, the reduction in the formation of AGEs in HUVECs caused by glycine treatment was inhibited by Glo1 inhibition.	Glycine	72-79	glyoxalase 1	Rattus norvegicus	107-111
30944692-11	2019	Taken together, our study provides evidence that glycine might inhibit the AGE/RAGE pathway and subsequent oxidative stress by improving Glo1 function, thus protecting against diabetic macrovascular complications.	Glycine	49-56	glyoxalase 1	Rattus norvegicus	137-141
30572191-6	2019	Obtained results showed that the UA could increase amount of doxorubicin (Dox) entering the cell to accumulate in nuclei, decrease the efflux ratio of digoxin comparable to the effects of the known inhibitor verapamil by acting as a P-gp substrate, decrease the content of intracellular alanine, lactate, pyruvate, glucose, alpha-ketoglutarate, glutamate, glutamine, aspartate, serine, and glycine.	Glycine	390-397	ATP binding cassette subfamily B member 1	Homo sapiens	233-237
30718913-1	2019	N-myristoyltransferase (NMT) attaches the fatty acid myristate to the N-terminal glycine of proteins to sort them into soluble and membrane-bound fractions.	Glycine	81-88	N-myristoyltransferase 1	Homo sapiens	0-22
30718913-1	2019	N-myristoyltransferase (NMT) attaches the fatty acid myristate to the N-terminal glycine of proteins to sort them into soluble and membrane-bound fractions.	Glycine	81-88	N-myristoyltransferase 1	Homo sapiens	24-27
30136411-0	2019	Glycine-modified growth hormone secretagogues identified in seized doping material.	Glycine	0-7	growth hormone 1	Homo sapiens	17-31
30618614-3	2018	TDP-43 is an RNA binding protein with glycine-rich domains that binds to more than 6,000 RNAs in the human brain.	Glycine	38-45	TAR DNA binding protein	Homo sapiens	0-6
30535023-3	2019	A search of the sheep genome using the human KRTAP20-1 sequence revealed a homologous open reading frame on chromosome 1, which would encode a high glycine-tyrosine KAP.	Glycine	148-155	keratin associated protein 20-1	Homo sapiens	45-54
30482727-6	2019	Comparing across iGluR subtypes, these results are similar to glycine-binding GluN1 and GluN3A NMDA subunits and differ from glutamate-binding GluA2 and GluN2A subunits.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	78-83
29951967-2	2019	This pathogenic mutation results in a deletion of 153 amino acids from glycine at position 970 (G970) to threonine at 1122 (T1122) in the CFTR protein without a frameshift.	Glycine	71-78	CF transmembrane conductance regulator	Homo sapiens	138-142
30425098-0	2019	Desensitizing plant EPSP synthase to glyphosate: Optimized global sequence context accommodates a glycine-to-alanine change in the active site.	Glycine	98-105	3-phosphoshikimate 1-carboxyvinyltransferase 2	Zea mays	20-33
30606120-4	2019	METHODS: We here report that a recently identified genetic variant, c.553G > T in the APOA5 gene which causes a substitution of a cysteine for a glycine residue at amino acid residue 185(G185C) is also associated with increased TG levels.	Glycine	145-152	apolipoprotein A5	Homo sapiens	86-91
30488955-7	2019	In the propositus and father, a novel mutation c.1373 A &gt; G was found in exon 10 of ITGB3 resulting in the substitution of an aspartic acid for a glycine (p.Asp458Gly).	Glycine	149-156	integrin subunit beta 3	Homo sapiens	87-92
30255931-9	2018	Furthermore, two patients on VPA polytherapy developed acute pancreatitis, and two pediatric patients with heterozygous p.Q1236H variants and mutations in IQSEC2 and GLDC, respectively, had elevated levels of VPA metabolites in urine, elevated plasma glycine, and/or increased acylglycine excretion.	Glycine	251-258	IQ motif and Sec7 domain ArfGEF 2	Homo sapiens	155-161
30060218-8	2018	Both mcm5 and s2 modification of wobble uridine strongly stabilizes G2 U35 mismatches when ${\rm{tRNA} }^{\rm Glu}_{\rm UUC}$ misreads the GGA Gly codon but has weaker effects on other mismatches.	Glycine	143-146	MCM DNA helicase complex subunit MCM5	Saccharomyces cerevisiae S288C	5-9
30479053-5	2018	In the molecular modeling study, compound 4e (docking score = -8.70) showed important hydrogen bond interaction with the amino acids LYS 329, SER 137, GLY 136 and pi-pi interactions with PHE 189 at the active site of GABA-AT.	Glycine	151-154	4-aminobutyrate aminotransferase	Homo sapiens	217-224
30138575-8	2018	In WT mice, increments of Gly-Sar-induced Isc were inhibited by the luminal application of a NHE3-specific inhibitor S3226 in a dose-dependent fashion.	Glycine	26-29	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	93-97
30342177-2	2018	N-myristoylation (Myr) is an eukaryotic N-terminal co- or post-translational protein modification in which the enzyme N-myristoyltransferase (NMT) transfers a fatty acid (C14:0) to the N-terminal glycine residues of several cellular key proteins.	Glycine	196-203	N-myristoyltransferase 1	Homo sapiens	142-145
29715549-7	2018	However, in eukaryotes, SEPHS1 contains other amino acids such as Thr, Arg, Gly, or Leu at the catalytic domain, and SEPHS2 contains only a Sec.	Glycine	76-79	selenophosphate synthetase 1	Homo sapiens	24-30
30347803-2	2018	ASC-MC and PSC-MC had glycine as the major amino acid with the contents of 341.8 +- 4.2 and 344.5 +- 3.2 residues/1000 residues, respectively.	Glycine	22-29	PYD and CARD domain containing	Homo sapiens	0-3
30315519-8	2018	Our results showed a novel homozygous mutation (c.9368G&gt;A) in a substitution of a conserved glycine residue into a glutamic acid in the exon 67 of SZT2 gene.	Glycine	95-102	SZT2 subunit of KICSTOR complex	Homo sapiens	150-154
30401430-6	2018	NMR studies of hydrogel PrPC reveal a distinct alpha-helical conformation for natively unfolded amino-terminal Gly and Ala residues.	Glycine	111-114	prion protein	Homo sapiens	24-28
30425522-12	2018	The presence of a glycine at position 778 in ERBB2 was suggested to be a common feature of drug sensitivity mutations.	Glycine	18-25	erb-b2 receptor tyrosine kinase 2	Homo sapiens	45-50
29909197-3	2018	Caspase-3 as an apoptosis indicator could specifically cleave the N-terminus of biotinylated DEVD-peptide (biotin-Gly-Asp-Gly-Asp-Glu-Val-Asp-Gly-Cys) immobilized on the Au nanoparticle-decorated TiO2 nanotube arrays (TiO2/Au NTAs) substrate.	Glycine	114-117	caspase 3	Homo sapiens	0-9
29909197-3	2018	Caspase-3 as an apoptosis indicator could specifically cleave the N-terminus of biotinylated DEVD-peptide (biotin-Gly-Asp-Gly-Asp-Glu-Val-Asp-Gly-Cys) immobilized on the Au nanoparticle-decorated TiO2 nanotube arrays (TiO2/Au NTAs) substrate.	Glycine	122-125	caspase 3	Homo sapiens	0-9
30349298-14	2018	Conclusion: Together, these results suggest that Pim1 contributes to proliferation and gly-colysis in OC via interaction with MYC and may serve as a potential target in the treatment of OC patients.	Glycine	87-90	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	49-53
30323304-4	2018	The amino acids glycine and phenylalanine and the energy metabolites citrate and glycerol were negatively associated with eGFR in all the cohorts, while alanine, valine and pyruvate depicted opposite association in diabetics (positive) and non-diabetics (negative).	Glycine	16-23	epidermal growth factor receptor	Homo sapiens	122-126
30149018-1	2018	The glucagon-like peptide 1 receptor (GLP-1R) can be activated by a number of endogenous peptide hormones, including extended, processed, glycine extended and carboxy-terminally amidated versions of glucagon-like peptide 1 (GLP-1).	Glycine	138-145	glucagon	Homo sapiens	4-27
30149018-1	2018	The glucagon-like peptide 1 receptor (GLP-1R) can be activated by a number of endogenous peptide hormones, including extended, processed, glycine extended and carboxy-terminally amidated versions of glucagon-like peptide 1 (GLP-1).	Glycine	138-145	glucagon	Homo sapiens	38-43
30139821-0	2018	Correction to "Identification of AICP as a GluN2C-Selective N-Methyl-D-Aspartate Receptor Superagonist at the GluN1 Glycine Site".	Glycine	116-123	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	110-115
30185558-5	2018	ASCT1-KO mice display lower levels of brain d-serine along with higher levels of l-alanine, l-threonine, and glycine.	Glycine	109-116	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	Mus musculus	0-5
30003938-8	2018	D1 dopamine receptor activation induced an increase in hnRNP H nuclear immunostaining as detected by immunocytochemistry with a C-domain directed antibody containing epitope near the glycine-rich domain but not with an N-domain specific antibody.	Glycine	183-190	heterogeneous nuclear ribonucleoprotein H1	Rattus norvegicus	55-62
30242198-2	2018	In many organisms, heme biosynthesis starts with the production of 5-aminolevulinic acid (ALA) from glycine and succinyl-coenzyme A, a process catalyzed by a homodimeric enzyme, pyridoxal 5"-phosphate (PLP)-dependent 5-aminolevulinate synthase (ALAS).	Glycine	100-107	5'-aminolevulinate synthase 1	Homo sapiens	245-249
30340819-9	2018	Intake of glycine significantly inhibited allergy development in a concentration dependent manner as indicated by a reduction in; acute allergic skin response, anaphylaxis, serum mMCP-1 and serum levels of whey specific IgE.	Glycine	10-17	mast cell protease 1	Mus musculus	179-185
30039134-4	2018	In addition to spectral changes due to protonation/deprotonation of the carboxyl group for lower pH-values around the pKa value (~2.3), the spectra of glycine exhibited further changes in the higher-pH region near the pKb value of glycine (dissociation constant of amino group ~9.5).	Glycine	151-158	AKT serine/threonine kinase 1	Homo sapiens	218-221
30185558-7	2018	Furthermore, ASCT1-KO mice exhibited deficits in motor function, spatial learning, and affective behavior, along with changes in the relative contributions of d-serine vs. glycine in mediating NMDA receptor activity.	Glycine	172-179	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	Mus musculus	13-18
30258354-2	2018	Gal-3 structure comprises unusual tandem repeats of proline and glycine-rich short stretches bound to a carbohydrate-recognition domain (CRD).	Glycine	64-71	lectin, galactose binding, soluble 3	Mus musculus	0-5
30131116-7	2018	DDX17 utilizes distinct RNA binding motifs for its role in efficient HIV replication, and we identify RNA binding motifs essential for its role, while the Walker A, Walker B (DEAD), Q motif and the glycine doublet motif are all dispensable.	Glycine	198-205	DEAD-box helicase 17	Homo sapiens	0-5
30217234-7	2018	RESULTS: Ion channels exhibited cut-off effects associated with hydrocarbon molar water solubility in the following order of decreasing solubility: Nav1.2   Nav1.4   TRESK   TREK-1 &gt; GABAA &gt;&gt; glycine.	Glycine	201-208	potassium two pore domain channel subfamily K member 18	Homo sapiens	166-171
30217234-7	2018	RESULTS: Ion channels exhibited cut-off effects associated with hydrocarbon molar water solubility in the following order of decreasing solubility: Nav1.2   Nav1.4   TRESK   TREK-1 &gt; GABAA &gt;&gt; glycine.	Glycine	201-208	potassium two pore domain channel subfamily K member 2	Homo sapiens	174-180
30152697-3	2018	The peptide sequence Arg-Gly-Asp (RGD), which is present in a number of endogenous integrin ligands like fibronectin, vitronectin, and related proteins of the extracellular matrix (ECM), has been extensively used as a targeting vector for therapeutic as well as diagnostic purposes, and cilengitide, a cyclic RGD peptide, has entered clinical trials for the treatment of various cancers.	Glycine	25-28	fibronectin 1	Homo sapiens	105-116
30006415-7	2018	The complex structure of MAGI1-PDZ3/nephrin-PBM reveals that the Gly at the -3 position of nephrin-PBM is the determining feature for MAGI1-PDZ3 recognition, which sharply contrasts with the typical PDZ/PBM binding mode.	Glycine	65-68	membrane associated guanylate kinase, WW and PDZ domain containing 1	Homo sapiens	25-30
29572562-4	2018	Here, we describe a consanguineous family with autosomal recessive OI caused by a novel homozygous glycine substitution in COL1A2, NM_000089.3: c.604G&gt;A, p.(Gly202Ser), detected by whole-genome sequencing.	Glycine	99-106	collagen type I alpha 2 chain	Homo sapiens	123-129
29572562-9	2018	Interestingly, the parents and one sister, all carriers of the COL1A2 glycine mutation, did not have manifestations of OI.	Glycine	70-77	collagen type I alpha 2 chain	Homo sapiens	63-69
29572562-10	2018	In summary, we report on autosomal recessive OI caused by a homozygous glycine-to-serine substitution in COL1A2, leading to severe skeletal fragility.	Glycine	71-78	collagen type I alpha 2 chain	Homo sapiens	105-111
30006415-7	2018	The complex structure of MAGI1-PDZ3/nephrin-PBM reveals that the Gly at the -3 position of nephrin-PBM is the determining feature for MAGI1-PDZ3 recognition, which sharply contrasts with the typical PDZ/PBM binding mode.	Glycine	65-68	membrane associated guanylate kinase, WW and PDZ domain containing 1	Homo sapiens	134-139
29345399-7	2018	Glycine can revert the inflammation due to the action of TNF-alpha by controlling the MMPs quantity and activity.	Glycine	0-7	tumor necrosis factor	Rattus norvegicus	57-66
30044634-2	2018	Fibronectin (Fn) holds two peptide sequences that favor cell adhesion: the Arg-Gly-Asp (RGD) loop on the tenth type-III domain (Fn-III10) and the Pro-His-Ser-Arg-Asn (PHSRN) synergy site on the ninth type-III domain (Fn-III9).	Glycine	79-82	fibronectin 1	Homo sapiens	0-11
30044634-2	2018	Fibronectin (Fn) holds two peptide sequences that favor cell adhesion: the Arg-Gly-Asp (RGD) loop on the tenth type-III domain (Fn-III10) and the Pro-His-Ser-Arg-Asn (PHSRN) synergy site on the ninth type-III domain (Fn-III9).	Glycine	79-82	fibronectin 1	Homo sapiens	13-15
29758302-5	2018	These cells respond to GABA (EC50 0.33 +- 0.18 muM), glycine (EC50 11.0 +- 3.7 muM) and additional ligands in line with previous reports from patch clamp technologies.	Glycine	53-60	latexin	Homo sapiens	79-82
30084355-4	2018	Cells lacking Scs2/Scs22 performed spindle positioning via MT end capture-shrinkage mechanism, requiring dynein anchorage to an ER- and mitochondria-independent population of Num1, dynein motor activity, and CAP-Gly domain of dynactin Nip100/p150Glued subunit.	Glycine	212-215	phospholipid metabolism-regulating protein SCS22	Saccharomyces cerevisiae S288C	19-24
29752946-10	2018	The amino acids hydroxyproline, proline, lysine, glycine and alanine induced the triglyceride accumulation and expression of Adiponectin.	Glycine	49-56	adiponectin, C1Q and collagen domain containing	Homo sapiens	125-136
29752946-12	2018	TGFbeta mRNA expression showed a significant decrease with proline, alanine, glycine, lysine and isoleucine.	Glycine	77-84	transforming growth factor beta 1	Homo sapiens	0-7
29753073-4	2018	In diabetic rats, glycine stimulated insulin secretion; enhanced plasma glutathione (GSH), catalase and superoxide dismutase levels; reduced plasma 8-hydroxy-2 deoxyguanosine and islet p22phox levels; and improved islet beta-cell mitochondrial degeneration and insulin granule degranulation.	Glycine	18-25	catalase	Rattus norvegicus	91-99
29753073-4	2018	In diabetic rats, glycine stimulated insulin secretion; enhanced plasma glutathione (GSH), catalase and superoxide dismutase levels; reduced plasma 8-hydroxy-2 deoxyguanosine and islet p22phox levels; and improved islet beta-cell mitochondrial degeneration and insulin granule degranulation.	Glycine	18-25	cytochrome b-245 alpha chain	Rattus norvegicus	185-192
29753073-6	2018	Glycine transporter-1 inhibitor blocked the antioxidative effect of glycine by reducing the intracellular GSH content, and glycine receptor inhibitor reversed the glycine antioxidative effect by blocking p22phox.	Glycine	123-130	cytochrome b-245 alpha chain	Rattus norvegicus	204-211
29893665-3	2018	The crystal structures of the domain from two strains of IBV, M41 (virulent) and Beaudette (avirulent), identified a key difference; M41 contains a conserved triple-glycine motif, whilst Beaudette contains a glycine-to-serine mutation that is predicted to abolish ADRP activity.	Glycine	165-172	DSCAM antisense RNA 1	Homo sapiens	62-65
29893665-3	2018	The crystal structures of the domain from two strains of IBV, M41 (virulent) and Beaudette (avirulent), identified a key difference; M41 contains a conserved triple-glycine motif, whilst Beaudette contains a glycine-to-serine mutation that is predicted to abolish ADRP activity.	Glycine	165-172	DSCAM antisense RNA 1	Homo sapiens	133-136
29893665-3	2018	The crystal structures of the domain from two strains of IBV, M41 (virulent) and Beaudette (avirulent), identified a key difference; M41 contains a conserved triple-glycine motif, whilst Beaudette contains a glycine-to-serine mutation that is predicted to abolish ADRP activity.	Glycine	208-215	DSCAM antisense RNA 1	Homo sapiens	62-65
29916244-4	2018	Consistent with experiments, it is found that the Gly and Ala modifications lead to insulin dimers with reduced stability by 4 and 5 kcal/mol from thermodynamic integration and 4 and 8 kcal/mol from results using molecular mechanics-generalized Born surface area, respectively.	Glycine	50-53	insulin	Homo sapiens	84-91
29402177-1	2018	Leucine-rich repeat kinase 2 (LRRK2) G2019S (glycine to serine) is the most common mutation associated with sporadic and familial Parkinson"s disease (PD) with 80% penetrance by age 70.	Glycine	45-52	leucine rich repeat kinase 2	Homo sapiens	0-28
29402177-1	2018	Leucine-rich repeat kinase 2 (LRRK2) G2019S (glycine to serine) is the most common mutation associated with sporadic and familial Parkinson"s disease (PD) with 80% penetrance by age 70.	Glycine	45-52	leucine rich repeat kinase 2	Homo sapiens	30-35
29784880-6	2018	We also report that an arginine residue within the Arg-Gly-Gly domain of TLS, Arg-476, serves as the major determinant for binding to pncRNA.	Glycine	55-58	FUS RNA binding protein	Homo sapiens	73-76
29784880-6	2018	We also report that an arginine residue within the Arg-Gly-Gly domain of TLS, Arg-476, serves as the major determinant for binding to pncRNA.	Glycine	59-62	FUS RNA binding protein	Homo sapiens	73-76
29887499-3	2018	Here, we investigate the process of agonist binding to the GluN2A (glutamate binding) and GluN1 (glycine binding) NMDA receptor subtypes using long-timescale unbiased molecular dynamics simulations.	Glycine	97-104	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	90-95
29887499-6	2018	Glycine, on the other hand, binds to the GluN1 LBD via an "unguided-diffusion" mechanism, whereby glycine finds its binding site primarily by random thermal fluctuations.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	41-46
29887499-6	2018	Glycine, on the other hand, binds to the GluN1 LBD via an "unguided-diffusion" mechanism, whereby glycine finds its binding site primarily by random thermal fluctuations.	Glycine	98-105	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	41-46
29917241-5	2018	ABSTRACT: NMDA receptors (NMDARs) are tetrameric complexes comprising two glycine-binding GluN1 and two glutamate-binding GluN2 subunits.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	90-95
30259778-10	2018	However, gly-ApoA-I and the relative intensity of ApoA-I glycation showed no significant differences between the HTB and LTB groups.	Glycine	9-12	apolipoprotein A1	Homo sapiens	13-19
30091703-4	2018	Accordingly, the uracil discriminator base, serving as a negative determinant, prevents Gly-tRNAGly misediting by DTD and this protection is augmented by EF-Tu.	Glycine	88-91	Tu translation elongation factor, mitochondrial	Homo sapiens	154-159
29938281-0	2018	Auto-oxidation promoted sp3 C-H arylation of glycine derivatives.	Glycine	45-52	Sp3 transcription factor	Homo sapiens	24-27
29800261-3	2018	TLS/FUS binding to G-quadruplex telomere DNA and telomeric repeat-containing RNA depends especially on RGG3, comprising Arg-Gly-Gly repeats with proline- and arginine-rich regions.	Glycine	124-127	FUS RNA binding protein	Homo sapiens	0-3
29800261-3	2018	TLS/FUS binding to G-quadruplex telomere DNA and telomeric repeat-containing RNA depends especially on RGG3, comprising Arg-Gly-Gly repeats with proline- and arginine-rich regions.	Glycine	124-127	FUS RNA binding protein	Homo sapiens	4-7
29800261-3	2018	TLS/FUS binding to G-quadruplex telomere DNA and telomeric repeat-containing RNA depends especially on RGG3, comprising Arg-Gly-Gly repeats with proline- and arginine-rich regions.	Glycine	128-131	FUS RNA binding protein	Homo sapiens	0-3
29800261-3	2018	TLS/FUS binding to G-quadruplex telomere DNA and telomeric repeat-containing RNA depends especially on RGG3, comprising Arg-Gly-Gly repeats with proline- and arginine-rich regions.	Glycine	128-131	FUS RNA binding protein	Homo sapiens	4-7
29802438-3	2018	Mechanistic studies were able to identify several "new targets", such as the inhibition of spinal glycine transporters or of inflammatory signaling as induced by tumor necrosis factor alpha.	Glycine	98-105	tumor necrosis factor	Homo sapiens	162-189
29345399-8	2018	These data indicated that the molecules involved to remodeling process of extracellular matrix are modulated both by TNF-alpha and the availability of collagen precursors; in fact, this study indicates the glycine can be useful for treatment of inflammation and for modulating tenocytes metabolism in tendons.	Glycine	206-213	tumor necrosis factor	Rattus norvegicus	117-126
29959345-8	2018	HrpE was able to interact with plant Glycine-Rich Proteins from citrus (CsGRP) and Arabidopsis (AtGRP-3).	Glycine	37-44	glycine-rich protein 3	Arabidopsis thaliana	96-103
29663696-6	2018	In the work reported here, we examined the roles of the different beta-tubulin isotypes in response to glutamate/glycine treatment, and found that both betaII and betaIII bind to glutathione in the presence of ROS, especially betaIII.	Glycine	113-120	NLR family pyrin domain containing 3	Homo sapiens	152-170
29356040-8	2018	This signal transduction was initiated by competitive binding of CD147 with integrin beta1 that interrupted the interaction between the Arg-Gly-Asp motif of fibronectin and integrin beta1.	Glycine	140-143	fibronectin 1	Homo sapiens	157-168
29644724-6	2018	In functional studies, the GluN2A-A643D mutation increased the potency of the agonists L-glutamate and glycine and decreased the potency of endogenous negative modulators, including protons, magnesium and zinc but reduced agonist-evoked peak current response in mammalian cells, suggesting that this mutation has a mixed effect on N-methyl-d-aspartate receptor function.	Glycine	103-110	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	27-33
29966365-2	2018	NR1 and NR3 subunits bind glycine, while NR2 subunits bind glutamate for full activation.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-3
29672864-11	2018	Specifically, inhibition of menin resulted in diminished expression of SSP genes, reduced H3K4me3 enrichment at the PHGDH promoter, and complete abrogation of de novo serine and glycine biosynthesis, as demonstrated by metabolic tracing studies with 13 C-labeled glucose.	Glycine	178-185	menin 1	Homo sapiens	28-33
29698679-0	2018	Glycine confers neuroprotection through PTEN/AKT signal pathway in experimental intracerebral hemorrhage.	Glycine	0-7	AKT serine/threonine kinase 1	Rattus norvegicus	45-48
29750297-3	2018	The structure of secreted type II collagen contains a core area with a triple helical glycine (Gly)-X-Y domain, and the replacement of Gly in this region as a result of COL2A1 mutations may damage the structure of type II collagen.	Glycine	95-98	collagen type II alpha 1 chain	Homo sapiens	169-175
29750297-3	2018	The structure of secreted type II collagen contains a core area with a triple helical glycine (Gly)-X-Y domain, and the replacement of Gly in this region as a result of COL2A1 mutations may damage the structure of type II collagen.	Glycine	135-138	collagen type II alpha 1 chain	Homo sapiens	169-175
29698679-8	2018	However, glycine treatment decreased PTEN protein level and increased the phosphorylation level of AKT (p-AKT) in the perihematomal area.	Glycine	9-16	AKT serine/threonine kinase 1	Rattus norvegicus	99-102
29698679-8	2018	However, glycine treatment decreased PTEN protein level and increased the phosphorylation level of AKT (p-AKT) in the perihematomal area.	Glycine	9-16	AKT serine/threonine kinase 1	Rattus norvegicus	104-109
29698679-11	2018	Nevertheless, Akt Inhibitor IV abolished the neuroprotective effects of glycine after ICH.	Glycine	72-79	AKT serine/threonine kinase 1	Rattus norvegicus	14-17
29698679-12	2018	Together, our findings demonstrate, for the first time, the protective role of glycine on ICH rats, and suggest that the neuroprotective effect of glycine was mediated through PTEN/Akt signal pathway.	Glycine	147-154	AKT serine/threonine kinase 1	Rattus norvegicus	181-184
29762687-10	2018	The glycine treatment group had greater levels of expression of an antiapoptotic gene (Bcl2) in mature oocytes and cumulus cells and lesser levels of expression of a proapoptotic gene (Bax) in PA blastocysts (P &lt; 0.05).	Glycine	4-11	BCL2 apoptosis regulator	Homo sapiens	87-91
29930756-7	2018	Growth of HER2-normal MCF7 cells is unaffected under these conditions whereas HER2/neu-positive cells display unchanged neutral lipid content, AMPK activation, inhibition of fatty acid synthesis and significantly altered glutamine, glucose and serine/glycine metabolism.	Glycine	251-258	erb-b2 receptor tyrosine kinase 2	Homo sapiens	83-86
29762687-10	2018	The glycine treatment group had greater levels of expression of an antiapoptotic gene (Bcl2) in mature oocytes and cumulus cells and lesser levels of expression of a proapoptotic gene (Bax) in PA blastocysts (P &lt; 0.05).	Glycine	4-11	BCL2 associated X, apoptosis regulator	Homo sapiens	185-188
29550635-0	2018	Participation of the IKK-alpha/beta complex in the inhibition of the TNF-alpha/NF-kappaB pathway by glycine: Possible involvement of a membrane receptor specific to adipocytes.	Glycine	100-107	tumor necrosis factor	Homo sapiens	69-78
29550635-1	2018	Glycine modulates inflammatory processes mediated by macrophages and adipocytes through decreasing the secretion of TNF-alpha, IL-6, and leptin, while increasing adiponectin.	Glycine	0-7	tumor necrosis factor	Homo sapiens	116-125
29550635-1	2018	Glycine modulates inflammatory processes mediated by macrophages and adipocytes through decreasing the secretion of TNF-alpha, IL-6, and leptin, while increasing adiponectin.	Glycine	0-7	interleukin 6	Homo sapiens	127-131
29550635-1	2018	Glycine modulates inflammatory processes mediated by macrophages and adipocytes through decreasing the secretion of TNF-alpha, IL-6, and leptin, while increasing adiponectin.	Glycine	0-7	adiponectin, C1Q and collagen domain containing	Homo sapiens	162-173
29550635-3	2018	However, glycine upstream mainly influences the IkappaB kinase (IKK) complex, a multi-protein kinase complex considered a critical point in regulation of the NF-kappaB pathway; whether that is responsible for the TNF-alpha-induced phosphorylation of IkB has not been explored.	Glycine	9-16	tumor necrosis factor	Homo sapiens	213-222
29550635-5	2018	In this research, participation of the IKK-alpha/beta complex in the inhibition of the TNF-alpha/NF-kappaB pathway by glycine was evaluated and associated with the synthesis and secretion of inflammatory cytokines in 3T3-L1 adipocytes.	Glycine	118-125	tumor necrosis factor	Homo sapiens	87-96
29550635-7	2018	Glycine decreased the IKK-alpha/beta complex and the phosphorylation of NF-kappaB, diminishing the expression and secretion of IL-6 and TNF-alpha, but increasing that of adiponectin.	Glycine	0-7	interleukin 6	Homo sapiens	127-131
29550635-7	2018	Glycine decreased the IKK-alpha/beta complex and the phosphorylation of NF-kappaB, diminishing the expression and secretion of IL-6 and TNF-alpha, but increasing that of adiponectin.	Glycine	0-7	tumor necrosis factor	Homo sapiens	136-145
29550635-7	2018	Glycine decreased the IKK-alpha/beta complex and the phosphorylation of NF-kappaB, diminishing the expression and secretion of IL-6 and TNF-alpha, but increasing that of adiponectin.	Glycine	0-7	adiponectin, C1Q and collagen domain containing	Homo sapiens	170-181
29550635-10	2018	In conclusion, the reduction of TNF-alpha and IL-6 and suppression of the TNF-alpha/NF-kappaB pathway by glycine may be explained in part by inhibition of the IKK-alpha/beta complex, with a possible participation of GlyR in 3T3-L1 adipocytes.	Glycine	105-112	tumor necrosis factor	Homo sapiens	74-83
29481666-4	2018	Gene-based tests identified two novel genes harboring missense variants of MAF &lt;1% that show aggregate association with amino acid levels: PYCR1 with glycine (Pgene = 1.5x10-6) and BCAT2 with valine (Pgene = 7.4x10-7); neither gene was implicated by single variant association tests.	Glycine	153-160	branched chain amino acid transaminase 2	Homo sapiens	184-189
29511087-8	2018	The alanine-scanning experiments revealed that residues Tyr-34, Gln-38, Gly-39, and Leu-45 (in the AB loop) and Pro-153 (in the D-helix) had specific roles in activating OSMR but not LIFR signaling, whereas Leu-40 and Cys-49 (in the AB loop), and Phe-160 and Lys-163 (in the D-helix) were required for activation of both receptors.	Glycine	72-75	LIF receptor subunit alpha	Homo sapiens	183-187
29019702-3	2018	We have recently reported that transforming growth factor (TGF)-beta, a key cytokine that promotes fibrogenesis, induces the expression of the enzymes of the de novo serine and glycine synthesis pathway in human lung fibroblasts, and that phosphoglycerate dehydrogenase (PHGDH; the first and rate-limiting enzyme of the pathway) is required to promote collagen protein synthesis downstream of TGF-beta.	Glycine	177-184	transforming growth factor beta 1	Homo sapiens	31-68
29688779-10	2018	RESULTS A nonsynonymous mutation at ovine Chr3:193,691,195, which generated a glycine-to-arginine amino acid change within the predicted Slco1b3 protein, was significantly associated with hyperbilirubinemia and predicted to be deleterious.	Glycine	78-85	solute carrier organic anion transporter family member 1B3	Ovis aries	137-144
29305854-10	2018	Astrocytes grown from mice with a copy number variant associated with psychosis, which have four copies of the GLDC gene, showed a more rapid production of d-serine and a reduction in glycine in the culture medium.	Glycine	184-191	glycine decarboxylase	Mus musculus	111-115
29411870-0	2018	Specific glycine to alanine mutation eliminates dynamic interaction of polymeric GlyT1a N-terminus with Coomassie Brilliant Blue G-250.	Glycine	9-16	solute carrier family 6 member 9	Homo sapiens	81-86
29695495-2	2018	Previous studies have shown that mammalian Mre11 is methylated at multiple arginines in its C-terminal Glycine-Arginine-Rich motif (GAR) by protein arginine methyltransferase PRMT1.	Glycine	103-110	MRE11 homolog, double strand break repair nuclease	Homo sapiens	43-48
29802295-4	2018	Mutation of this residue to glycine, the equivalent residue in chicken ASIC1, diminished the rASIC3 Ca2+ block effect.	Glycine	28-35	acid sensing ion channel subunit 1	Gallus gallus	71-76
29802295-4	2018	Mutation of this residue to glycine, the equivalent residue in chicken ASIC1, diminished the rASIC3 Ca2+ block effect.	Glycine	28-35	acid sensing ion channel subunit 3	Rattus norvegicus	93-99
29795045-6	2018	The residue that plays a major role in determining the diverse pKa values of the proton shuttle is the one in position four, namely His for hCA II and Gly for hCA VII.	Glycine	151-154	carbonic anhydrase 7	Homo sapiens	159-166
29768206-5	2018	Alanine substitution of a unique glycine in helix alpha1 stabilizes BOK, as shown by thermal shift and urea denaturation analyses, and significantly inhibits MOMP, liposome permeabilization, and cell death.	Glycine	33-40	BCL2 family apoptosis regulator BOK	Homo sapiens	68-71
29356901-0	2018	Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis.	Glycine	0-7	adiponectin, C1Q and collagen domain containing	Homo sapiens	31-42
29356901-7	2018	However, the mRNA levels of adiponectin and interleukin-10 (IL-10), two adipose-derived adipocytokines with anti-inflammatory effects, were greatly enhanced (P &lt; 0.05) by 2 mmol/L glycine.	Glycine	183-190	adiponectin, C1Q and collagen domain containing	Homo sapiens	28-39
29356901-11	2018	In conclusion, glycine exposure enhanced the mRNA levels of adipose-derived adiponectin and IL-10 without affecting adipogenesis and lipolysis in 3T3-L1 adipocytes.	Glycine	15-22	adiponectin, C1Q and collagen domain containing	Homo sapiens	76-87
29681798-8	2018	We observed the most prominent effect when residues GluN1(L657) and GluN2B(I655) were deleted or altered to glycine.	Glycine	108-115	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	52-57
29983966-5	2018	Glycine and Pro-Hyp attenuated the DSS-induced rise in colonic IL-6 and TNF-alpha, as well as peripheral IL-1beta, IL-6, and TNF-alpha.	Glycine	0-7	interleukin 6	Mus musculus	63-67
29983966-5	2018	Glycine and Pro-Hyp attenuated the DSS-induced rise in colonic IL-6 and TNF-alpha, as well as peripheral IL-1beta, IL-6, and TNF-alpha.	Glycine	0-7	tumor necrosis factor	Mus musculus	72-81
29983966-5	2018	Glycine and Pro-Hyp attenuated the DSS-induced rise in colonic IL-6 and TNF-alpha, as well as peripheral IL-1beta, IL-6, and TNF-alpha.	Glycine	0-7	tumor necrosis factor	Mus musculus	125-134
29642420-8	2018	To achieve this balance EBNA1 has evolved a unique repeat sequence of glycines and alanines that controls its own rate of mRNA translation.	Glycine	70-78	EBNA-1	Human gammaherpesvirus 4	24-29
29555853-5	2018	In contrast, neurons lacking spine-enriched NF-kappaB are selectively impaired in NF-kappaB-dependent gene expression induced by elevated excitatory synaptic stimulation (bicuculline or glycine).	Glycine	186-193	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	44-53
29555853-5	2018	In contrast, neurons lacking spine-enriched NF-kappaB are selectively impaired in NF-kappaB-dependent gene expression induced by elevated excitatory synaptic stimulation (bicuculline or glycine).	Glycine	186-193	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	82-91
29576319-2	2018	Here, we show that the CAP-Gly and coiled-coil domains of Bik1 interact with the C-terminal ETF peptide of Bim1 and the C-terminal tail region of Stu2, respectively.	Glycine	27-30	microtubule-binding protein BIM1	Saccharomyces cerevisiae S288C	107-111
29471495-4	2018	Protein arginine methyltransferase (PRMT) 1, PRMT3 and PRMT6 all methylate TOP3B in vitro at its C-terminal arginine (R) and glycine (G)-rich motif.	Glycine	125-132	protein arginine methyltransferase 3	Homo sapiens	45-50
29471495-4	2018	Protein arginine methyltransferase (PRMT) 1, PRMT3 and PRMT6 all methylate TOP3B in vitro at its C-terminal arginine (R) and glycine (G)-rich motif.	Glycine	125-132	protein arginine methyltransferase 6	Homo sapiens	55-60
29429593-15	2018	INTERPRETATION: In patients with symptomatic COPD, severe or very severe airflow limitation, and an exacerbation history despite maintenance therapy, extrafine BDP/FF/G significantly reduced the rate of moderate-to-severe exacerbations compared with IND/GLY, without increasing the risk of pneumonia.	Glycine	254-257	AT-rich interaction domain 3B	Homo sapiens	160-168
29662311-4	2018	Results: Atomic force microscopy-based force spectroscopy measurements showed a significant decrease both on the fibrinogen-erythrocyte binding force and on its frequency for fibrinogen with the D97E mutation, indicating that the corresponding arginine-glycine-aspartate sequence (residues 95-97) is involved in this interaction, and supporting that the fibrinogen receptor on erythrocytes has a beta3 subunit.	Glycine	253-260	fibrinogen beta chain	Homo sapiens	113-123
29662311-4	2018	Results: Atomic force microscopy-based force spectroscopy measurements showed a significant decrease both on the fibrinogen-erythrocyte binding force and on its frequency for fibrinogen with the D97E mutation, indicating that the corresponding arginine-glycine-aspartate sequence (residues 95-97) is involved in this interaction, and supporting that the fibrinogen receptor on erythrocytes has a beta3 subunit.	Glycine	253-260	fibrinogen beta chain	Homo sapiens	175-185
29662311-4	2018	Results: Atomic force microscopy-based force spectroscopy measurements showed a significant decrease both on the fibrinogen-erythrocyte binding force and on its frequency for fibrinogen with the D97E mutation, indicating that the corresponding arginine-glycine-aspartate sequence (residues 95-97) is involved in this interaction, and supporting that the fibrinogen receptor on erythrocytes has a beta3 subunit.	Glycine	253-260	fibrinogen beta chain	Homo sapiens	175-185
29229647-6	2018	Based on the crystal structure of the p38alpha-TAB1 complex we replaced threonine 185 of p38alpha with glycine (T185G) to prevent an intramolecular hydrogen bond with Asp150 from being formed.	Glycine	103-110	mitogen-activated protein kinase 14	Homo sapiens	38-46
29600168-8	2018	This transition was located in the first base pair of codon 367 (GGA&gt;AGA) in exon 3 of MYOC and was predicted to be a missense substitution of glycine to arginine (p.G367R) in myocilin.	Glycine	146-153	myocilin	Homo sapiens	90-94
29600168-8	2018	This transition was located in the first base pair of codon 367 (GGA&gt;AGA) in exon 3 of MYOC and was predicted to be a missense substitution of glycine to arginine (p.G367R) in myocilin.	Glycine	146-153	myocilin	Homo sapiens	179-187
29196110-6	2018	With regards to the cleavage behavior of neprilysin, a strong preference for Gly at P1 was found, while Gly, Ala and Val were well accepted at P1" upon cleavage of tropoelastin and skin elastin.	Glycine	77-80	membrane metalloendopeptidase	Homo sapiens	41-51
29675131-5	2018	Glycine treatment decreases the levels of oxidative stress markers in liver from SF rats and increases the concentrations of glutathione (GSH) and gamma-glutamylcysteine and the amount of gamma-glutamylcysteine synthetase (gamma-GCS), a key enzyme of GSH biosynthesis in liver from SF rats.	Glycine	0-7	glutamate-cysteine ligase, catalytic subunit	Rattus norvegicus	188-221
29675131-5	2018	Glycine treatment decreases the levels of oxidative stress markers in liver from SF rats and increases the concentrations of glutathione (GSH) and gamma-glutamylcysteine and the amount of gamma-glutamylcysteine synthetase (gamma-GCS), a key enzyme of GSH biosynthesis in liver from SF rats.	Glycine	0-7	glutamate-cysteine ligase, catalytic subunit	Rattus norvegicus	223-232
29439465-3	2018	Arginine to cysteine substitutions that occur at either the X or Y position within the Gly-X-Y cause different phenotypes like Stickler syndrome and congenital spondyloepiphyseal dysplasia (SEDC).	Glycine	87-90	collagen type II alpha 1 chain	Homo sapiens	190-194
29288497-3	2018	Most ARS genes in these cellular compartments are distinct, but two genes are common, encoding aminoacyl-tRNA synthetases of glycine (GARS) and lysine (KARS) in both mitochondria and the cytosol.	Glycine	125-132	lysyl-tRNA synthetase 1	Homo sapiens	152-156
29290056-8	2018	Together our results suggest that 5-HT inhibits the release of glycine by activation of 5-HT1B/D receptors.	Glycine	63-70	5-hydroxytryptamine receptor 1B	Homo sapiens	88-94
29024779-2	2018	In this study, we examine the kinetics associated with human NTCP-dependent transport of two quantitatively important bile acids comprising the human bile acid pool, chenodeoxycholic acid and glycine-chenodeoxycholate, and secondary bile salt, 3-sulfo-glycolithocholate of potential toxicological significance.	Glycine	192-199	solute carrier family 10 member 1	Homo sapiens	61-65
29255089-2	2018	The RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providing S6 flexibility and minimizing amino acid clashes.	Glycine	48-56	ryanodine receptor 1	Homo sapiens	4-8
29255089-2	2018	The RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providing S6 flexibility and minimizing amino acid clashes.	Glycine	48-56	ryanodine receptor 1	Homo sapiens	97-101
29255089-2	2018	The RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providing S6 flexibility and minimizing amino acid clashes.	Glycine	58-61	ryanodine receptor 1	Homo sapiens	4-8
29255089-2	2018	The RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providing S6 flexibility and minimizing amino acid clashes.	Glycine	58-61	ryanodine receptor 1	Homo sapiens	97-101
29255089-2	2018	The RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providing S6 flexibility and minimizing amino acid clashes.	Glycine	71-74	ryanodine receptor 1	Homo sapiens	4-8
29255089-2	2018	The RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providing S6 flexibility and minimizing amino acid clashes.	Glycine	71-74	ryanodine receptor 1	Homo sapiens	97-101
29296993-2	2018	The biological activity of glycine-extended gastrin (Ggly) is dependent on the binding of Fe3+ ions in vitro and in vivo.	Glycine	27-34	gastrin	Mus musculus	44-51
28833667-5	2018	Such DOTPI-TRAP conjugates were decorated with 3 Gly-urea-Lys (KuE) motifs for targeting prostate-specific membrane antigen (PSMA), employing Cu-catalyzed (CuAAC) as well as strain-promoted (SPAAC) click chemistry.	Glycine	49-52	folate hydrolase 1	Homo sapiens	125-129
29354277-1	2018	Spondyloepiphyseal dysplasia congenita (SEDC) is an extremely rare autosomal dominant chondrodysplasia that is usually caused by substitution of glycine with another amino acid in the triple helical region of COL2A1.	Glycine	145-152	collagen type II alpha 1 chain	Homo sapiens	40-44
29354277-1	2018	Spondyloepiphyseal dysplasia congenita (SEDC) is an extremely rare autosomal dominant chondrodysplasia that is usually caused by substitution of glycine with another amino acid in the triple helical region of COL2A1.	Glycine	145-152	collagen type II alpha 1 chain	Homo sapiens	209-215
29131545-3	2018	The involvement of the BH4 domain in Bcl-2"s antiapoptotic functions has been proposed based on Gly-based substitutions of the Ile14/Val15 amino acids, two hydrophobic residues located in the center of Bcl-2"s BH4 domain.	Glycine	96-99	BCL2 apoptosis regulator	Homo sapiens	37-42
29375301-4	2017	Glycine transporter 1 (GlyT1) plays an important role in regulating extracellular glycine concentrations.	Glycine	82-89	solute carrier family 6 member 9	Homo sapiens	0-21
29375301-4	2017	Glycine transporter 1 (GlyT1) plays an important role in regulating extracellular glycine concentrations.	Glycine	82-89	solute carrier family 6 member 9	Homo sapiens	23-28
29543922-10	2018	Also, a missense mutation in COL1A2 changing Gly Cys in the central part of the triple helical domain of the collagen type I molecule caused OI type III.	Glycine	45-48	collagen type I alpha 2 chain	Homo sapiens	29-35
29094215-1	2018	Plasma glycine level is low in patients with obesity or diabetes and the improvement of insulin resistance increases plasma glycine concentration.	Glycine	7-14	insulin	Homo sapiens	88-95
29094215-1	2018	Plasma glycine level is low in patients with obesity or diabetes and the improvement of insulin resistance increases plasma glycine concentration.	Glycine	124-131	insulin	Homo sapiens	88-95
29886758-9	2018	Based on these results, we for the first time, demonstrated the isolation of anti-G17-Gly human scFv and VL antibodies with potential therapeutic applications in G17-Gly-responsive tumors.	Glycine	86-89	immunglobulin heavy chain variable region	Homo sapiens	96-100
29886758-9	2018	Based on these results, we for the first time, demonstrated the isolation of anti-G17-Gly human scFv and VL antibodies with potential therapeutic applications in G17-Gly-responsive tumors.	Glycine	166-169	immunglobulin heavy chain variable region	Homo sapiens	96-100
29239245-9	2018	We conclude that elevated branched-chain amino acids and reduced glycine are currently the most robust and consistent amino acid markers for prediabetes, insulin resistance, and future T2D.	Glycine	65-72	insulin	Homo sapiens	154-161
30032156-11	2018	RESULTS: Glycine significantly decreased lactate dehydrogenase at 1 h and both aspartate aminotransferase and alanine aminotransferase at 2 h after pneumoperitoneum from 477 +- 43, 154 +- 17, and 60 +- 6 U/L in controls to 348 +- 25, 101 +- 11, and 34 +- 3 U/L, respectively (p &lt; 0.05).	Glycine	9-16	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	79-105
29580877-15	2018	This approach allowed the successful confirmation of the binding of Gly-Sar at the mM range and revealed for the first time the KD of the antiviral prodrug valacyclovir to the PepT1 homolog at around 50 muM.	Glycine	68-71	solute carrier family 15 member 1	Homo sapiens	176-181
30724160-9	2018	In glycated low-density lipoprotein/glycated high-density lipoprotein-treated groups, native high-density lipoprotein treatment reduced malondialdehyde, protein carbonyl, annexin-V, caspase-3/9 levels (P &lt; 0.001, P &lt; 0.01) and increased glutathione; nitric oxide levels (only with gly-HDL).	Glycine	3-6	caspase 3	Homo sapiens	182-191
30097105-3	2018	Our previous work has shown that generating the critical, glycine-centered radical species on CutC requires posttranslational modification by an S-adenosyl-l-methionine (SAM)-dependent radical-activating protein (CutD) harboring an oxygen-sensitive [4Fe-4S] cofactor.	Glycine	58-65	cutC copper transporter	Homo sapiens	94-98
28732179-6	2017	However, HYD-1 (Lys-Ile-Lys-Met-Val-Ile-Ser-Trp-Lys-Gly), an integrin antagonist, inhibited the KGF-enhanced epithelial adhesion and rete peg elongation.	Glycine	52-55	fibroblast growth factor 7	Homo sapiens	96-99
30099452-7	2018	The docking results revealed that compound 8 forms 2 hydrogen bonds with the residues of Gly-216 and Ile-218 in 11beta-HSD1, that is to say compound 8 maybe a good 11beta-HSD1 inhibitor.	Glycine	89-92	hydroxysteroid 11-beta dehydrogenase 1	Homo sapiens	112-123
30099452-7	2018	The docking results revealed that compound 8 forms 2 hydrogen bonds with the residues of Gly-216 and Ile-218 in 11beta-HSD1, that is to say compound 8 maybe a good 11beta-HSD1 inhibitor.	Glycine	89-92	hydroxysteroid 11-beta dehydrogenase 1	Homo sapiens	164-175
29246256-13	2017	TNF-alpha in serum and IL-6 and G-CSF in sputum tended to decline at the end of the glycine period (p = 0.061, p = 0.068 and p = 0.04, respectively, vs placebo).	Glycine	84-91	tumor necrosis factor	Homo sapiens	0-9
29246305-3	2017	GLDC is a component of the mitochondrial glycine cleavage system, and its high expression is required for growth and tumorigenic capacity.	Glycine	41-48	glycine decarboxylase	Mus musculus	0-4
29129681-2	2017	The glycine to serine mutation (G2019S) in leucine-rich repeat kinase 2 (LRRK2) is the most common genetic cause for PD and has been shown to impair mitochondrial function and morphology in multiple model systems.	Glycine	4-11	leucine rich repeat kinase 2	Homo sapiens	43-71
29129681-2	2017	The glycine to serine mutation (G2019S) in leucine-rich repeat kinase 2 (LRRK2) is the most common genetic cause for PD and has been shown to impair mitochondrial function and morphology in multiple model systems.	Glycine	4-11	leucine rich repeat kinase 2	Homo sapiens	73-78
29107708-6	2018	We also found that the presence of Gly-64 and Cys-70, both of which are conserved only in the switch II region, a putative effector binding domain, of Rab20 is required for the inhibitory effect of Rab20 on neurite outgrowth.	Glycine	35-38	RAB20, member RAS oncogene family	Rattus norvegicus	151-156
29107708-6	2018	We also found that the presence of Gly-64 and Cys-70, both of which are conserved only in the switch II region, a putative effector binding domain, of Rab20 is required for the inhibitory effect of Rab20 on neurite outgrowth.	Glycine	35-38	RAB20, member RAS oncogene family	Rattus norvegicus	198-203
28277064-7	2017	Platelet effects of a mouse monoclonal antibody targeting the glycine-binding region of GluN1 (GluN1-S2) were tested in assays of platelet activation, aggregation and thrombus formation.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	88-93
30647695-9	2017	On the other hand, Se and GLY reduced hydrogen peroxide-mediated production of TNF-alpha, IL-1, IL-6 and expression of iNOS and NF-kappaB.	Glycine	26-29	tumor necrosis factor	Homo sapiens	79-88
30647695-9	2017	On the other hand, Se and GLY reduced hydrogen peroxide-mediated production of TNF-alpha, IL-1, IL-6 and expression of iNOS and NF-kappaB.	Glycine	26-29	interleukin 6	Homo sapiens	96-100
28905384-3	2017	Synaptically released glycine also enhanced tonic glycinergic currents and resulted in decreased parvalbumin-expressing interneuron excitability.	Glycine	22-29	parvalbumin	Mus musculus	97-108
28277064-7	2017	Platelet effects of a mouse monoclonal antibody targeting the glycine-binding region of GluN1 (GluN1-S2) were tested in assays of platelet activation, aggregation and thrombus formation.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	95-103
28277064-12	2017	The epitope of anti-GluN1-S2 was mapped to alpha-helix H located within the glycine-binding clamshell of GluN1, where the antibody binding was computationally predicted to impair opening of the NMDAR channel.	Glycine	76-83	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	20-28
28277064-12	2017	The epitope of anti-GluN1-S2 was mapped to alpha-helix H located within the glycine-binding clamshell of GluN1, where the antibody binding was computationally predicted to impair opening of the NMDAR channel.	Glycine	76-83	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	20-25
29096248-3	2017	We detected a novel RGD (Arg-Gly-Asp)-containing peptide derived from the C-terminal portion of fibrinogen in the sera of metastatic patients that appeared to control the EMT (epithelial-mesenchymal transition) of cancer cells, in a process associated with miR-199a-3p.	Glycine	29-32	fibrinogen beta chain	Homo sapiens	96-106
29178930-4	2017	In the current study, a mouse model was generated harboring a glycine to aspartic acid residue change in the Walker A motif of the ATPase domain of Msh3.	Glycine	62-69	mutS homolog 3	Mus musculus	148-152
28796435-1	2017	HLA-DRB1*11:143 has one nucleotide change from HLA-DRB1*11:01:01 where Aspartic Acid (70) is changed to Glycine.	Glycine	104-111	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-8
29145464-4	2017	Here, we demonstrate that NP can interact and colocalize with heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 in mammalian cells and that the interaction may occur via direct binding to the glycine-rich domain (GRD) of hnRNP A2/B1.	Glycine	196-203	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	225-236
29116138-0	2017	Vascular endothelial growth factor signaling requires glycine to promote angiogenesis.	Glycine	54-61	vascular endothelial growth factor A	Homo sapiens	0-34
29116138-6	2017	(2) Activation of glycine transporter 1(GlyT1) induced by VEGF led to an increase in intracellular glycine.	Glycine	18-25	solute carrier family 6 member 9	Homo sapiens	40-45
29116138-6	2017	(2) Activation of glycine transporter 1(GlyT1) induced by VEGF led to an increase in intracellular glycine.	Glycine	18-25	vascular endothelial growth factor A	Homo sapiens	58-62
29116138-8	2017	These original results highlight glycine as a necessary mediator in VEGF signalling via the GlyT1-glycine-mTOR-VDAC1 axis pathway.	Glycine	33-40	vascular endothelial growth factor A	Homo sapiens	68-72
29116138-8	2017	These original results highlight glycine as a necessary mediator in VEGF signalling via the GlyT1-glycine-mTOR-VDAC1 axis pathway.	Glycine	33-40	solute carrier family 6 member 9	Homo sapiens	92-97
29116138-8	2017	These original results highlight glycine as a necessary mediator in VEGF signalling via the GlyT1-glycine-mTOR-VDAC1 axis pathway.	Glycine	33-40	mechanistic target of rapamycin kinase	Homo sapiens	106-110
29116138-8	2017	These original results highlight glycine as a necessary mediator in VEGF signalling via the GlyT1-glycine-mTOR-VDAC1 axis pathway.	Glycine	98-105	vascular endothelial growth factor A	Homo sapiens	68-72
29116138-8	2017	These original results highlight glycine as a necessary mediator in VEGF signalling via the GlyT1-glycine-mTOR-VDAC1 axis pathway.	Glycine	98-105	solute carrier family 6 member 9	Homo sapiens	92-97
29116138-8	2017	These original results highlight glycine as a necessary mediator in VEGF signalling via the GlyT1-glycine-mTOR-VDAC1 axis pathway.	Glycine	98-105	mechanistic target of rapamycin kinase	Homo sapiens	106-110
28796435-1	2017	HLA-DRB1*11:143 has one nucleotide change from HLA-DRB1*11:01:01 where Aspartic Acid (70) is changed to Glycine.	Glycine	104-111	major histocompatibility complex, class II, DR beta 1	Homo sapiens	47-55
29204107-2	2017	The CD13-targeting moiety NGR was synthesized and cyclized by native chemical ligation (NCL) instead of disulfide bridging, leading to a cyclic peptide backbone: cyclo(Cys-Asn-Gly-Arg-Gly) (coNGR).	Glycine	176-179	reticulon 4 receptor	Mus musculus	26-29
28262924-3	2017	D-serine and glycine are coagonists of N-methyl-D-aspartate (NMDA) receptor subunit GRIN1.	Glycine	13-20	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	84-89
29204107-2	2017	The CD13-targeting moiety NGR was synthesized and cyclized by native chemical ligation (NCL) instead of disulfide bridging, leading to a cyclic peptide backbone: cyclo(Cys-Asn-Gly-Arg-Gly) (coNGR).	Glycine	184-187	reticulon 4 receptor	Mus musculus	26-29
28872880-8	2017	Furthermore, the study also permitted the identification of ten novel prospective allosteric sites named NP1 to NP10, involving in most of the cases protein structural elements that control kinase activation including the activation loop, the catalytic loop, the alphaC helix, the L16 loop, and the glycine-rich loop.	Glycine	299-306	nuclear receptor subfamily 4 group A member 1	Homo sapiens	112-116
29066782-5	2017	Similar dependency on quenching of ROS due to influential hydrogen bond interaction with glycine residue of Sod1 oxidative stress protein and increased apoptosis were observed in cells.	Glycine	89-96	superoxide dismutase 1, soluble	Danio rerio	108-112
28654788-1	2017	In this study, a new strategy for highly selective and extremely efficient removal of toxic oxyanions (Cr(VI), Se(VI), and As(V)) from aqueous solutions using zwitterionic glycine intercalated layered double hydroxide (Gly-LDH) was reported.	Glycine	172-179	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	123-128
29017490-9	2017	Sanger sequencing confirmed the ss2019324576 variant in the affected calves and sperm of Energy P. This mutation is located within the collagen triple helix repeat and causes an exchange of glycine to serine (p.996G &gt; S) in COL2A1.	Glycine	190-197	collagen type II alpha 1 chain	Bos taurus	227-233
28864764-3	2017	Because interaction of kindlin-2 with alphaVbeta3 requires the C-terminal three residues of the beta3 cytoplasmic tail (Arg-Gly-Thr; RGT), optogenetic probes LOVpep and ePDZ1 were fused to beta3DeltaRGT-GFP and mCherry-kindlin-2, respectively, and expressed in beta3 integrin-null microvascular endothelial cells.	Glycine	124-127	FERM domain containing kindlin 2	Homo sapiens	23-32
28654788-3	2017	The obtained results show that the adsorption capacity and selectivity factor of oxyanions through ion exchange mechanism in NO3-LDH is lower than Gly-LDH.	Glycine	147-150	NBL1, DAN family BMP antagonist	Homo sapiens	125-128
28915088-6	2017	Concentrations of glycine, alanine, alpha-amino isobutyric acid, and glutamic acid in the plume and in the ambient ocean could all be above 0.01 muM just due to abiotic production.	Glycine	18-25	latexin	Homo sapiens	145-148
31966360-0	2017	Glycine protects against non-alcoholic hepatitis by downregulation of the TLR4 signaling pathway.	Glycine	0-7	toll-like receptor 4	Rattus norvegicus	74-78
31966360-1	2017	OBJECTIVE: To evaluate the effect of glycine on regulation of the hepatic toll-like receptor 4 (TLR4) signaling pathway by metabolic endotoxemia in a rat model of non-alcoholic steatohepatitis (NASH).	Glycine	37-44	toll-like receptor 4	Rattus norvegicus	74-94
31966360-1	2017	OBJECTIVE: To evaluate the effect of glycine on regulation of the hepatic toll-like receptor 4 (TLR4) signaling pathway by metabolic endotoxemia in a rat model of non-alcoholic steatohepatitis (NASH).	Glycine	37-44	toll-like receptor 4	Rattus norvegicus	96-100
31966360-9	2017	With concomitant treatment with glycine, endotoxin levels decreased, and TNFalpha and IL-6 levels in plasma and liver were significantly decreased compared to NASH rats.	Glycine	32-39	tumor necrosis factor	Rattus norvegicus	73-81
31966360-9	2017	With concomitant treatment with glycine, endotoxin levels decreased, and TNFalpha and IL-6 levels in plasma and liver were significantly decreased compared to NASH rats.	Glycine	32-39	interleukin 6	Rattus norvegicus	86-90
28883613-6	2017	To mimic inflammation during atherogenesis, human myeloperoxidase was incubated with glycine, H2O2, malondialdehyde, and a lysine analog in PBS at a physiological temperature, which resulted in M2FA generation.	Glycine	85-92	myeloperoxidase	Homo sapiens	50-65
28734208-4	2017	The above three binding sites were mutated by Glycine residue individually and generate three complex systems such as Abeta(His6Gly)-Heme, Abeta(His13Gly)-Heme and Abeta(His14Gly)-Heme.	Glycine	46-53	amyloid beta precursor protein	Homo sapiens	118-123
28514141-3	2017	In particular, compounds 15a and 16a are potent GluN2C-specific superagonists at the GluN1 subunit with agonist efficacies of 398% and 308% compared to glycine.	Glycine	152-159	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	85-90
27699582-5	2017	The Gly/Gly genotype of the PGC-1 gene Gly482Ser polymorphism influences the effects of moderate-intensity exercise training on low-density lipoprotein cholesterol and total cholesterol concentrations in older people.	Glycine	4-7	PPARG coactivator 1 alpha	Homo sapiens	28-33
27699582-5	2017	The Gly/Gly genotype of the PGC-1 gene Gly482Ser polymorphism influences the effects of moderate-intensity exercise training on low-density lipoprotein cholesterol and total cholesterol concentrations in older people.	Glycine	8-11	PPARG coactivator 1 alpha	Homo sapiens	28-33
28676394-0	2017	The glycine hinge of transmembrane segment 2 modulates the subcellular localization and gating properties in TREK channels.	Glycine	4-11	potassium two pore domain channel subfamily K member 2	Homo sapiens	109-113
28676394-2	2017	The important functions of transmembrane segment 4 (M4)-glycine hinge in TREK channel gating have been characterized, but the roles of M2-hinge (the equivalent residue of M4-hinge) remain unclear.	Glycine	56-63	potassium two pore domain channel subfamily K member 2	Homo sapiens	73-77
28627122-6	2017	The alanine scanning and shuffling the amino acid residues of BP4 (Tyr-Lys-Asp-Gly) demonstrated that the Tyr-Lys-Asp-Gly consensus sequence is important for the inhibitory effect of the peptide on hypothermia.	Glycine	79-82	Blood pressure QTL 4	Rattus norvegicus	62-65
28760974-2	2017	Most NMDA receptors comprise two glycine-binding GluN1 and two glutamate-binding GluN2 subunits (GluN2A-D).	Glycine	33-40	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	49-54
28807563-3	2017	Using mass spectrometry, we show that in virus particles of a Lelystad variant, the signal peptide of GP5 was absent due to cleavage between glycine-34 and asparagine-35.	Glycine	141-148	glycoprotein V platelet	Homo sapiens	102-105
28658579-6	2017	These findings highlight the importance of the conformational plasticity and accessibility of the arginine-glycine-aspartic acid (RGD) binding site in FN, which, in turn, mediates cell signaling in physiological and synthetic environments.	Glycine	107-114	fibronectin 1	Homo sapiens	151-153
28588066-0	2017	Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site.	Glycine	101-108	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	95-100
28588066-8	2017	We show that GluN1/2C superagonism of AICP and DCS is mediated by overlapping but distinct mechanisms and that AICP selectively enhances responses from recombinant GluN1/2C receptors in the presence of physiological glycine concentrations.	Glycine	216-223	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	164-169
28468946-4	2017	In this study, we present the crystal structure of the isolated ligand-binding domain of the GluN1-GluN2A NMDA receptor in complex with the GluN1 agonist glycine and the GluN2A antagonist NVP-AAM077.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	93-98
28431321-8	2017	Supplementation of apolipoprotein E-deficient (apoE-/-) mice with glycine for 40 days significantly decreased the triglyceride levels in serum and in peritoneal macrophages (MPMs) isolated from the mice (by 19%).	Glycine	66-73	apolipoprotein E	Mus musculus	47-55
28904723-3	2017	Molecular analysis of the newborn revealed a novel mutation at position c.560 (c.560 G &gt; T) of the exon 12 in the COL1A2 gene; which lead to the glycine modification with valine (p.Gly187Val) at codon 187.	Glycine	148-155	collagen type I alpha 2 chain	Homo sapiens	117-123
28389817-7	2017	In summary, this study shows that mutations of arginine to glycine in DmHsp22 ACD induce a number of structural changes, some of which differ from those described in mammalian sHsps.	Glycine	59-66	Heat shock protein 22	Drosophila melanogaster	70-77
28431321-6	2017	Glycine, cysteine, alanine and leucine significantly decreased macrophage triglyceride content (by 24%-38%), through attenuated uptake of triglyceride-rich very low-density lipoprotein (VLDL) by macrophages.	Glycine	0-7	CD320 antigen	Mus musculus	186-190
28468946-4	2017	In this study, we present the crystal structure of the isolated ligand-binding domain of the GluN1-GluN2A NMDA receptor in complex with the GluN1 agonist glycine and the GluN2A antagonist NVP-AAM077.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	99-105
28468946-4	2017	In this study, we present the crystal structure of the isolated ligand-binding domain of the GluN1-GluN2A NMDA receptor in complex with the GluN1 agonist glycine and the GluN2A antagonist NVP-AAM077.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	140-145
28969000-5	2017	In univariate analysis, the HER2-positive group was shown to have higher levels of glycine and glutamate, compared to the HER2-negative group (P&lt;0.01, and P &lt;0.01, respectively).	Glycine	83-90	erb-b2 receptor tyrosine kinase 2	Homo sapiens	28-32
28620235-5	2017	The effect of glycine is sensitive to the antagonist of glycine-GluN1 binding site and blocked by Akt inhibition.	Glycine	14-21	AKT serine/threonine kinase 1	Rattus norvegicus	98-101
28620235-7	2017	This study suggests that glycine-induced neuroprotection is mediated in part by the non-ionotropic activity of NMDARs via Akt activation in cerebral ischemia-reperfusion injury.	Glycine	25-32	AKT serine/threonine kinase 1	Rattus norvegicus	122-125
28378791-7	2017	To validate this prediction, we perform electrophysiological analysis of full-length NMDARs with a glycosylation-preventing GluN1-N440Q mutation, and demonstrate an increase in the glycine EC50 value.	Glycine	181-188	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	124-129
28228639-5	2017	GluN1-G620R/GluN2A complexes showed a mild reduction in trafficking, a ~2-fold decrease in glutamate and glycine potency, a strong decrease in sensitivity to Mg2+ block, and a significant reduction of current responses to a maximal effective concentration of agonists.	Glycine	105-112	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-5
28228639-5	2017	GluN1-G620R/GluN2A complexes showed a mild reduction in trafficking, a ~2-fold decrease in glutamate and glycine potency, a strong decrease in sensitivity to Mg2+ block, and a significant reduction of current responses to a maximal effective concentration of agonists.	Glycine	105-112	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	12-18
28365212-1	2017	N-methyl-d-aspartate (NMDA) receptors assembled from GluN1 and GluN3 subunits are unique in that they form glycine-gated excitatory channels that are insensitive to glutamate and NMDA.	Glycine	107-114	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	53-58
28363510-12	2017	Putative binding sites for HCFC1 and its binding partner THAP11 were identified near genes of the glycine cleavage enzyme, providing a potential mechanistic link between HCFC1 mutations and increased glycine.	Glycine	98-105	THAP domain containing 11	Homo sapiens	57-63
28363510-12	2017	Putative binding sites for HCFC1 and its binding partner THAP11 were identified near genes of the glycine cleavage enzyme, providing a potential mechanistic link between HCFC1 mutations and increased glycine.	Glycine	200-207	THAP domain containing 11	Homo sapiens	57-63
28534738-5	2017	PSAA photoisomerization at the GluN1 clamshell hinge is sufficient to control glycine sensitivity and activation efficacy.	Glycine	78-85	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	31-36
28498836-9	2017	In the individuals with a COL1A2 mutation, 80% (8/10) of those with a glycine substitution located C terminal of p.Gly211 exhibited DGI in both dentitions while no individual (0/5) with a mutation N-terminal of this point (p = 0.007) exhibited DGI in either dentition.	Glycine	70-77	collagen type I alpha 2 chain	Homo sapiens	26-32
28198180-5	2017	CLPs containing 120 GFP molecules and those containing approximately 150 dye molecules were both shown to bind human integrin via a naturally occurring Arg-Gly-Asp motif found on an exposed loop of the VP7 trimeric spike.	Glycine	156-159	colipase	Homo sapiens	0-4
28198180-5	2017	CLPs containing 120 GFP molecules and those containing approximately 150 dye molecules were both shown to bind human integrin via a naturally occurring Arg-Gly-Asp motif found on an exposed loop of the VP7 trimeric spike.	Glycine	156-159	VP7	Bluetongue virus	202-205
28302935-7	2017	The glycine at amino acid position 435 in the C-terminal region is completely conserved in the trypsin-like serine protease family, including thrombin, FVII, protein C, plasmin, trypsin, and chymotrypsin.	Glycine	4-11	coagulation factor II, thrombin	Homo sapiens	142-150
28287329-1	2017	The cysteine protease ATG4B cleaves off one or more C-terminal residues of the inactive proform of proteins of the ortholog and paralog LC3 and GABARAP subfamilies of yeast Atg8 to expose a C-terminal glycine that is conjugated to phosphatidylethanolamine during autophagosome formation.	Glycine	201-208	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	173-177
28132911-1	2017	Leukotriene A4 hydrolase is a soluble enzyme with epoxide hydrolase and aminopeptidase activities catalysing the conversion of leukotriene A4 to leukotriene B4 and the hydrolysis of the peptide proline-glycine-proline.	Glycine	202-209	leukotriene A4 hydrolase	Homo sapiens	0-24
28213519-3	2017	Compared with all other neurotransmitter:sodium:symporters, GAT-1 and other members of the GABA transporter subfamily all contain an extra amino acid residue at or near a conserved glycine in transmembrane segment 10.	Glycine	181-188	solute carrier family 6 member 1	Homo sapiens	60-65
28213519-4	2017	Therefore, we studied the functional impact of deletion and replacement mutants of Gly-457 and its two adjacent residues in GAT-1.	Glycine	83-86	solute carrier family 6 member 1	Homo sapiens	124-129
27748994-10	2017	With an average of 178 mug/g Gly m 4 in SPI, Gly m 4 lowest observed adverse effect level can be calculated once clinical lowest observed adverse effect level data based on SPI are available.	Glycine	29-32	chromogranin A	Homo sapiens	40-43
27719884-7	2017	BBPs were the main peptidases involved in the PepT1 transport and the maximum hydrolysis rate was 11.4muM Gly/min.	Glycine	106-109	solute carrier family 15 member 1	Homo sapiens	46-51
27794528-2	2017	The mutation of G486D is located within MCM-box and the glycine at 486 in human MCM4 is conserved in Saccharomyces cerevisiae MCM4 and Sulfolobus solfataricus MCM.	Glycine	56-63	minichromosome maintenance complex component 4	Homo sapiens	80-84
27748994-10	2017	With an average of 178 mug/g Gly m 4 in SPI, Gly m 4 lowest observed adverse effect level can be calculated once clinical lowest observed adverse effect level data based on SPI are available.	Glycine	45-48	chromogranin A	Homo sapiens	40-43
27613478-10	2017	Glycine also significantly reduced astrocyte reactive transformation, microglia activation, and terminal deoxynucleotidyl transferase dUTP nick end labeling-positive (apoptotic) cell numbers in peri-lesional areas at 3 days after HI, and TNF-alpha mRNA expression in the injured hemisphere at 12 and 24 h after HI.	Glycine	0-7	DNA nucleotidylexotransferase	Rattus norvegicus	96-133
27613478-10	2017	Glycine also significantly reduced astrocyte reactive transformation, microglia activation, and terminal deoxynucleotidyl transferase dUTP nick end labeling-positive (apoptotic) cell numbers in peri-lesional areas at 3 days after HI, and TNF-alpha mRNA expression in the injured hemisphere at 12 and 24 h after HI.	Glycine	0-7	tumor necrosis factor	Rattus norvegicus	238-247
27613478-11	2017	CONCLUSION: Glycine protected neonatal rat brains against HI, in part by inhibiting TNF-alpha-induced inflammation and gliosis.	Glycine	12-19	tumor necrosis factor	Rattus norvegicus	84-93
27744583-5	2017	Because G85 and G591 correspond to a conserved Gly found in all MBDs, we introduced the mutations in the well-characterized MBD4.	Glycine	47-50	methyl-CpG binding domain 4, DNA glycosylase	Homo sapiens	124-128
28102596-3	2017	In addition, cEDS phenotype was reported in a small number of patients carrying the c.934C&gt;T mutation in COL1A1 that results in an uncommon substitution of a non-glycine residue in one Gly-Xaa-Yaa repeat of the pro-alpha1(I)-chain p.(Arg312Cys), which leads to disturbed collagen fibrillogenesis due to delayed removal of the type I procollagen N-propeptide.	Glycine	165-172	collagen type I alpha 2 chain	Homo sapiens	329-347
27919832-3	2017	In this study, we identified the glycine-rich domain (GRD) of hnRNP proteins as a unifying feature in splice site repression.	Glycine	33-40	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	62-67
29296957-2	2017	The interaction between the fibrinogen C-terminal gamma-chain peptide composed of residues gamma-404-411 (GAKQAGDV) and the Arg-Gly-Asp (RGD) binding pocket on alphaIIbbeta3 is required for fibrinogen-mediated platelet aggregation, but data suggest that other ancillary binding sites on both fibrinogen and alphaIIbbeta3 may lead to higher-affinity fibrinogen binding and clot retraction.	Glycine	128-131	fibrinogen beta chain	Homo sapiens	28-38
29296957-2	2017	The interaction between the fibrinogen C-terminal gamma-chain peptide composed of residues gamma-404-411 (GAKQAGDV) and the Arg-Gly-Asp (RGD) binding pocket on alphaIIbbeta3 is required for fibrinogen-mediated platelet aggregation, but data suggest that other ancillary binding sites on both fibrinogen and alphaIIbbeta3 may lead to higher-affinity fibrinogen binding and clot retraction.	Glycine	128-131	fibrinogen beta chain	Homo sapiens	190-200
29296957-2	2017	The interaction between the fibrinogen C-terminal gamma-chain peptide composed of residues gamma-404-411 (GAKQAGDV) and the Arg-Gly-Asp (RGD) binding pocket on alphaIIbbeta3 is required for fibrinogen-mediated platelet aggregation, but data suggest that other ancillary binding sites on both fibrinogen and alphaIIbbeta3 may lead to higher-affinity fibrinogen binding and clot retraction.	Glycine	128-131	fibrinogen beta chain	Homo sapiens	190-200
29296957-2	2017	The interaction between the fibrinogen C-terminal gamma-chain peptide composed of residues gamma-404-411 (GAKQAGDV) and the Arg-Gly-Asp (RGD) binding pocket on alphaIIbbeta3 is required for fibrinogen-mediated platelet aggregation, but data suggest that other ancillary binding sites on both fibrinogen and alphaIIbbeta3 may lead to higher-affinity fibrinogen binding and clot retraction.	Glycine	128-131	fibrinogen beta chain	Homo sapiens	190-200
27842890-2	2017	In this study, the heptapeptide leucine-threonine-valine-serine-proline-tryptophan-tyrosine (LTVSPWY) as a new small peptide for an anti-HER2 target was labeled by incorporating 99mTc to the cysteine-based ligands CGGG (Cys-Gly-Gly-Gly) and CSSS (Cys-Ser-Ser-Ser) linked to this peptide.	Glycine	224-227	erb-b2 receptor tyrosine kinase 2	Homo sapiens	137-141
27842890-2	2017	In this study, the heptapeptide leucine-threonine-valine-serine-proline-tryptophan-tyrosine (LTVSPWY) as a new small peptide for an anti-HER2 target was labeled by incorporating 99mTc to the cysteine-based ligands CGGG (Cys-Gly-Gly-Gly) and CSSS (Cys-Ser-Ser-Ser) linked to this peptide.	Glycine	228-231	erb-b2 receptor tyrosine kinase 2	Homo sapiens	137-141
27842890-2	2017	In this study, the heptapeptide leucine-threonine-valine-serine-proline-tryptophan-tyrosine (LTVSPWY) as a new small peptide for an anti-HER2 target was labeled by incorporating 99mTc to the cysteine-based ligands CGGG (Cys-Gly-Gly-Gly) and CSSS (Cys-Ser-Ser-Ser) linked to this peptide.	Glycine	228-231	erb-b2 receptor tyrosine kinase 2	Homo sapiens	137-141
28202787-6	2017	Intra-vmPFC administration of the glycine transport inhibitor ALX5407 prevented excessive premature responding by alcohol-exposed rats, and this was reliant on NMDA glycine site availability.	Glycine	34-41	formyl peptide receptor 2-like	Rattus norvegicus	62-65
28202787-6	2017	Intra-vmPFC administration of the glycine transport inhibitor ALX5407 prevented excessive premature responding by alcohol-exposed rats, and this was reliant on NMDA glycine site availability.	Glycine	165-172	formyl peptide receptor 2-like	Rattus norvegicus	62-65
27836665-1	2017	Gloverin2 is a cationic and glycine-rich antimicrobial peptide whose expression can be induced in fat body of silkworm (Bombyx mori) larvae exposed to bacteria.	Glycine	28-35	gloverin 2	Bombyx mori	0-9
27419919-0	2017	Glycine release from astrocytes via functional reversal of GlyT1.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	59-64
26796213-1	2017	d-Serine is a co-agonist of NMDA receptors (NMDARs) whose activity is potentially regulated by Asc-1 (SLC7A10), a transporter that displays high affinity for d-serine and glycine.	Glycine	171-178	solute carrier family 7 (cationic amino acid transporter, y+ system), member 10	Mus musculus	102-109
27873460-3	2017	Here, sortase A (srtA)-mediated transpeptidation is used to specifically conjugate triple glycine-modified monomethyl auristatin E (MMAE), a highly toxic antimitotic agent, to anti-CD20 ofatumumab (OFA) equipped with a short C-terminal LPETG (5 amino acids) tag at heavy chain (HL), which generates ADCs that show extremely strong potency in killing CD20 positive cancer cells.	Glycine	90-97	keratin 20	Homo sapiens	181-185
27873460-3	2017	Here, sortase A (srtA)-mediated transpeptidation is used to specifically conjugate triple glycine-modified monomethyl auristatin E (MMAE), a highly toxic antimitotic agent, to anti-CD20 ofatumumab (OFA) equipped with a short C-terminal LPETG (5 amino acids) tag at heavy chain (HL), which generates ADCs that show extremely strong potency in killing CD20 positive cancer cells.	Glycine	90-97	keratin 20	Homo sapiens	350-354
27921110-4	2017	In this study, we report the use of polyethyleneimine (PEI)-entrapped gold nanoparticles (Au PENPs) modified with an arginine-glycine-aspartic (Arg-Gly-Asp, RGD) peptide via a poly(ethylene glycol) (PEG) spacer as a vector for Bcl-2 (B-cell lymphoma-2) siRNA delivery to glioblastoma cells.	Glycine	148-151	BCL2 apoptosis regulator	Homo sapiens	227-232
27921110-4	2017	In this study, we report the use of polyethyleneimine (PEI)-entrapped gold nanoparticles (Au PENPs) modified with an arginine-glycine-aspartic (Arg-Gly-Asp, RGD) peptide via a poly(ethylene glycol) (PEG) spacer as a vector for Bcl-2 (B-cell lymphoma-2) siRNA delivery to glioblastoma cells.	Glycine	148-151	BCL2 apoptosis regulator	Homo sapiens	234-251
28043736-9	2017	We then identified amino acids independently associated with sufficient response, namely, leucine at position 26 of HLA-DRbeta1 and glycine-glycine-proline-methionine at positions 84-87 of HLA-DPbeta1.	Glycine	132-139	major histocompatibility complex, class II, DR beta 1	Homo sapiens	189-192
28059133-1	2017	The glycine-binding site of the N-methyl-D-aspartate receptor (NMDAR) subunit GluN1 is a potential pharmacological target for neurodegenerative disorders.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	78-83
28060902-12	2017	Our results suggest that conjugated bile acids (glycine and taurine) are preferred to unconjugated bile acids as substrates for OATP1B1 and OATP1B3.	Glycine	48-55	solute carrier organic anion transporter family member 1B3	Homo sapiens	140-147
28849491-2	2017	Ala, Gln, Gly, Lys, Val and taurine (Tau) are the most abundant free AAs in mammals, and some of these react with hypochlorite (HOCl/OCl-) produced by myeloperoxidase in activated phagocytes to form N-chloroamino acids (NCAA).	Glycine	10-13	occludin	Mus musculus	129-132
27836671-3	2017	Pre-treatment with glycine significantly attenuated murine cardiac hypertrophy induced by transverse aortic constriction or by administration of angiotensin II (Ang II).	Glycine	19-26	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	145-159
28828604-4	2017	The unique glial glycine-selective transporter GlyT1 (SLC6) is the main regulator of synaptic glycine concentrations, assisted by the neuronal GlyT2.	Glycine	17-24	solute carrier family 6 member 9	Homo sapiens	47-52
28828604-4	2017	The unique glial glycine-selective transporter GlyT1 (SLC6) is the main regulator of synaptic glycine concentrations, assisted by the neuronal GlyT2.	Glycine	94-101	solute carrier family 6 member 9	Homo sapiens	47-52
27769935-0	2017	The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs.	Glycine	35-42	C-X-C motif chemokine receptor 1	Rattus norvegicus	110-115
28828604-5	2017	The five additional glycine transporters ATB0,+, SNAT1, SNAT2, SNAT5, and LAT2 display broad amino acid specificity and have differential contributions to glial glycine transport.	Glycine	20-27	solute carrier family 38 member 5	Homo sapiens	63-68
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	4-11	solute carrier family 6 member 9	Homo sapiens	86-91
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	4-11	solute carrier family 38 member 5	Homo sapiens	189-194
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	4-11	solute carrier family 38 member 5	Homo sapiens	195-198
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	77-84	solute carrier family 6 member 9	Homo sapiens	86-91
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	77-84	solute carrier family 38 member 5	Homo sapiens	189-194
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	77-84	solute carrier family 38 member 5	Homo sapiens	195-198
27836671-3	2017	Pre-treatment with glycine significantly attenuated murine cardiac hypertrophy induced by transverse aortic constriction or by administration of angiotensin II (Ang II).	Glycine	19-26	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	161-167
27836671-6	2017	Co-culture experiments revealed that glycine could also antagonize Ang II stimulated release of transforming growth factor beta and endothelin-1 by cardiomyocytes, which prevented an over-production of collagens in rat fibroblasts.	Glycine	37-44	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	67-73
27836671-6	2017	Co-culture experiments revealed that glycine could also antagonize Ang II stimulated release of transforming growth factor beta and endothelin-1 by cardiomyocytes, which prevented an over-production of collagens in rat fibroblasts.	Glycine	37-44	endothelin 1	Rattus norvegicus	132-144
29375644-7	2017	Furthermore, metabolomics analysis showed that TGP treatment significantly attenuated CCl4-triggered deregulation of multiple metabolites in both urine and serum, including glycine, alanine, proline, and glutamine.	Glycine	173-180	C-C motif chemokine ligand 4	Rattus norvegicus	86-90
27658772-10	2017	RESULTS: The serine 482 variant of the human PGC1A protein had a shorter half-life than the glycine 482 variant when expressed in HepG2 cells.	Glycine	92-99	PPARG coactivator 1 alpha	Homo sapiens	45-50
27761847-3	2017	Recently, the role of alphav integrins, which recognize the Arg-Gly-Asp (RGD) tripeptide, in the release and signal transduction activation of TGFbeta1 became evident.	Glycine	64-67	transforming growth factor beta 1	Homo sapiens	143-151
27799304-0	2016	Consequences of Glycine Mutations in the Fibronectin-binding Sequence of Collagen.	Glycine	16-23	fibronectin 1	Homo sapiens	41-52
27292783-7	2017	However, there are GlyR-independent mechanisms for glycine cytoprotection and other possible binding molecules of glycine are the NMDA receptor and receptors GlyT1 and GlyT2.	Glycine	114-121	solute carrier family 6 member 9	Homo sapiens	158-163
27292783-8	2017	Although, in humans, the normal serum level of glycine is approximately 300 muM, increasing glycine intake can lead to blood levels of more than 900 muM that increase its benefic actions without having harmful side effects.	Glycine	92-99	latexin	Homo sapiens	149-152
27836973-4	2016	TGF-beta also induces the expression of the enzymes of the de novo serine synthesis pathway (phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine phosphatase (PSPH)) and de novo glycine synthesis (serine hydroxymethyltransferase 2 (SHMT2)).	Glycine	225-232	transforming growth factor beta 1	Homo sapiens	0-8
27908452-6	2017	The NO3- yield during ozonation was significantly higher for glycine than for trimethylamine and dimethylamine.	Glycine	61-68	NBL1, DAN family BMP antagonist	Homo sapiens	4-7
27908452-7	2017	Experiments with glycine also showed that NO3- was formed via an intermediate with a second-order rate constant of 7.7 +- 0.1 M-1s-1 while NH4+ was formed by an electron-transfer mechanism with O3 as confirmed from a hydroxyl radical (OH) yield of 24.7 +- 1.9%.	Glycine	17-24	NBL1, DAN family BMP antagonist	Homo sapiens	42-45
27799304-4	2016	Fluorescence polarization and solid-state assays indicated that Gly replacements at four sites within the Fn-binding sequence led to decreased Fn binding to denatured collagen.	Glycine	64-67	fibronectin 1	Homo sapiens	106-108
27799304-5	2016	Molecular dynamics simulations showed these Gly replacements interfered with the interaction of a collagen beta-strand with the beta-sheet structure of Fn modules seen in the high resolution crystal structure.	Glycine	44-47	fibronectin 1	Homo sapiens	152-154
27434150-1	2016	The Met-enkephalin, Tyr-Gly-Gly-Phe-Met, was synthesized by the solution-phase synthesis (SPS) methodology employing -OBzl group as carboxyls" protection, while the t-Boc groups were employed for the N-terminal alpha-amines" protection for the majority of the amino acids of the pentapeptide sequence.	Glycine	24-27	proopiomelanocortin	Homo sapiens	4-18
27941902-3	2016	The Src-family member Lyn contains a myristoylation site at glycine-2 and a palmitoylation site at cysteine-3, whereas c-Src has a myristoylation site at glycine-2 but not any palmitoylation sites.	Glycine	60-67	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	4-7
27941902-3	2016	The Src-family member Lyn contains a myristoylation site at glycine-2 and a palmitoylation site at cysteine-3, whereas c-Src has a myristoylation site at glycine-2 but not any palmitoylation sites.	Glycine	60-67	LYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	22-25
27941902-3	2016	The Src-family member Lyn contains a myristoylation site at glycine-2 and a palmitoylation site at cysteine-3, whereas c-Src has a myristoylation site at glycine-2 but not any palmitoylation sites.	Glycine	154-161	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	119-124
28101463-1	2016	Purpose: EGFRvIII as the most common mutant variant of the epidermal growth factor receptor is resulting from deletion of exons 2-7 in the coding sequence and junction of exons 1 and 8 through a novel glycine residue.	Glycine	201-208	epidermal growth factor receptor	Homo sapiens	59-91
27659424-8	2016	Elevations of hepatic mRNA levels for TNFalpha and chemokine (C-C motif) ligand 2 were also remarkably blunted in the glycine diet-fed mice.	Glycine	118-125	tumor necrosis factor	Mus musculus	38-46
27872106-8	2016	However, interactions of MTHFD1 rs2236225 polymorphism with both plasma serine and glycine were observed (Pinteraction=0.03 for both).	Glycine	83-90	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	Homo sapiens	25-31
27872106-11	2016	CONCLUSIONS: Our results showed that 2 common and functional polymorphisms in the MTHFD1 gene modulate the risk associations of plasma serine and glycine with AMI.	Glycine	146-153	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	Homo sapiens	82-88
27872106-12	2016	These findings emphasize the possible role of the MTHFD1 in regulating serine and glycine metabolism in relation to atherosclerotic complications.	Glycine	82-89	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	Homo sapiens	50-56
27872106-0	2016	Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial).	Glycine	90-97	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	Homo sapiens	0-41
27798331-0	2016	Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts.	Glycine	0-7	mechanistic target of rapamycin kinase	Homo sapiens	66-95
28035186-6	2016	Sequencing of the SOD1 gene by PCR revealed a missense mutation of G to C (c.37G&gt;C) in exon 1, and amino acid substitution of glycine by arginine (p.Gly13Arg).	Glycine	129-136	superoxide dismutase 1	Homo sapiens	18-22
27798331-0	2016	Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts.	Glycine	0-7	tripartite motif containing 63	Homo sapiens	114-119
27798331-4	2016	OBJECTIVE: This study was conducted with a mouse myoblast cell line, C2C12, to test the hypothesis that glycine activates protein kinase B/mammalian target of rapamycin (Akt/mTOR), as well as inhibits 5"-adenosine monophosphate-activated protein kinase (AMPK) and the expression of genes for proteolysis.	Glycine	104-111	mechanistic target of rapamycin kinase	Homo sapiens	139-168
27798331-4	2016	OBJECTIVE: This study was conducted with a mouse myoblast cell line, C2C12, to test the hypothesis that glycine activates protein kinase B/mammalian target of rapamycin (Akt/mTOR), as well as inhibits 5"-adenosine monophosphate-activated protein kinase (AMPK) and the expression of genes for proteolysis.	Glycine	104-111	AKT serine/threonine kinase 1	Homo sapiens	170-173
27798331-4	2016	OBJECTIVE: This study was conducted with a mouse myoblast cell line, C2C12, to test the hypothesis that glycine activates protein kinase B/mammalian target of rapamycin (Akt/mTOR), as well as inhibits 5"-adenosine monophosphate-activated protein kinase (AMPK) and the expression of genes for proteolysis.	Glycine	104-111	mechanistic target of rapamycin kinase	Homo sapiens	174-178
27798331-8	2016	Glycine treatment led to increased DNA replication (by 70-80%) while enhancing mTORC1 activation by upregulating Akt and inhibiting AMPK signaling (P &lt; 0.05).	Glycine	0-7	AKT serine/threonine kinase 1	Homo sapiens	113-116
27798331-11	2016	Moreover, glycine addition resulted in decreased mRNA levels for atrogin-1 and MuRF1 (by 20-40% and 30-50%, respectively; P &lt; 0.05).	Glycine	10-17	tripartite motif containing 63	Homo sapiens	79-84
27798331-12	2016	The repressing effect of glycine on the expression of MuRF1, instead of atrogin-1, was abolished by LY294002 (P &lt; 0.05).	Glycine	25-32	tripartite motif containing 63	Homo sapiens	54-59
27612722-4	2016	The linear concentration range of the proposed sensor for the l-Glycine, l-Cysteine, l-Tyrosine, and l-Phenylalanine were 0.2-70, 0.06-0.2, 0.01-0.1, and 0.2-10muM, while low limit of quantifications were 0.2, 0.06, 0.01, and 0.2muM, respectively.	Glycine	62-71	latexin	Homo sapiens	160-163
27811964-5	2016	Pathway enrichment and topology analysis identified that nitrogen metabolism, glycine, serine and threonine metabolism, aminoacyl-tRNA biosynthesis and taurine and hypotaurine metabolism were enriched after PARP inhibition in all three breast cancer cell lines.	Glycine	78-85	poly(ADP-ribose) polymerase 1	Homo sapiens	207-211
27742838-3	2016	In this study, we have utilized this disruptive effect of Gly-192 mutation to our advantage, by substituting this residue with amino acid residues of varying van der Waals volumes with the intent to modulate the affinity of GroEL toward fibrillogenic peptides.	Glycine	58-61	GroEL	Escherichia coli	224-229
27742838-6	2016	The chaperonins also displayed differential effects on alpha-synuclein fibril morphology, suggesting that through mutation of Gly-192, we may induce changes to the intermolecular affinities between GroEL and alpha-synuclein, leading to more efficient fibril suppression, and in specific cases, modulation of fibril morphology.	Glycine	126-129	GroEL	Escherichia coli	198-203
27816567-2	2016	Glutamate theories and findings from studies showing efficacy of sarcosine, an endogenous, non-selective glycine-reuptake inhibitor mediated by GlyT1, offer an alternative approach.	Glycine	105-112	solute carrier family 6 member 9	Homo sapiens	144-149
27799657-3	2016	By developing genetically engineered mouse models and primary pancreatic epithelial cells, and employing transcriptional, proteomics, and metabolic analyses, we find that oncogenic cooperation between LKB1 loss and KRAS activation is fuelled by pronounced mTOR-dependent induction of the serine-glycine-one-carbon pathway coupled to S-adenosylmethionine generation.	Glycine	295-302	serine/threonine kinase 11	Mus musculus	201-205
27773429-10	2016	Our data suggest that truncating SLC6A9 mutations lead to a distinct human neurological syndrome hallmarked by mildly elevated CSF glycine and normal serum glycine.	Glycine	131-138	solute carrier family 6 member 9	Homo sapiens	33-39
27773429-10	2016	Our data suggest that truncating SLC6A9 mutations lead to a distinct human neurological syndrome hallmarked by mildly elevated CSF glycine and normal serum glycine.	Glycine	156-163	solute carrier family 6 member 9	Homo sapiens	33-39
27533495-0	2016	The conformational IgE epitope profile of soya bean allergen Gly m 4.	Glycine	61-64	immunoglobulin heavy constant epsilon	Homo sapiens	19-22
27518042-4	2016	The co-repression occurs through binding of TDP-43 to mRNA(s) at specific UG/GU sequences and recruitment of the inhibitory CYFIP1-FMRP complex by its glycine-rich domain.	Glycine	151-158	TAR DNA binding protein	Homo sapiens	44-50
27518042-4	2016	The co-repression occurs through binding of TDP-43 to mRNA(s) at specific UG/GU sequences and recruitment of the inhibitory CYFIP1-FMRP complex by its glycine-rich domain.	Glycine	151-158	fragile X messenger ribonucleoprotein 1	Homo sapiens	131-135
27533495-2	2016	Conformational IgE epitopes of Gly m 4 are unknown.	Glycine	31-34	immunoglobulin heavy constant epsilon	Homo sapiens	15-18
27533495-3	2016	OBJECTIVE: To identify the IgE epitope profile of Gly m 4 in subjects with birch pollen-related soya allergy utilizing an epitope library presented by Gly m 4-type model proteins.	Glycine	50-53	immunoglobulin heavy constant epsilon	Homo sapiens	27-30
27533495-3	2016	OBJECTIVE: To identify the IgE epitope profile of Gly m 4 in subjects with birch pollen-related soya allergy utilizing an epitope library presented by Gly m 4-type model proteins.	Glycine	151-154	immunoglobulin heavy constant epsilon	Homo sapiens	27-30
27533495-5	2016	Specific IgE (Bet v 1/Gly m 4) was determined by ImmunoCAP.	Glycine	22-25	immunoglobulin heavy constant epsilon	Homo sapiens	9-12
27533495-10	2016	The avidities of serum IgE were 5.06 ng (allergic) and 1.8 ng (tolerant) as determined by EC50 for IgE binding to Gly m 4.	Glycine	114-117	immunoglobulin heavy constant epsilon	Homo sapiens	23-26
27533495-10	2016	The avidities of serum IgE were 5.06 ng (allergic) and 1.8 ng (tolerant) as determined by EC50 for IgE binding to Gly m 4.	Glycine	114-117	immunoglobulin heavy constant epsilon	Homo sapiens	99-102
27533495-13	2016	Gly m 4-specific IgE binding could be inhibited to up to 80% by model proteins harbouring individual IgE binding sites in an epitope-wise equimolar fashion.	Glycine	0-3	immunoglobulin heavy constant epsilon	Homo sapiens	17-20
27533495-13	2016	Gly m 4-specific IgE binding could be inhibited to up to 80% by model proteins harbouring individual IgE binding sites in an epitope-wise equimolar fashion.	Glycine	0-3	immunoglobulin heavy constant epsilon	Homo sapiens	101-104
27533495-15	2016	CONCLUSION AND CLINICAL RELEVANCE: Serum levels and avidity of Gly m 4-specific IgE do not correlate with clinical reactivity to soya.	Glycine	63-66	immunoglobulin heavy constant epsilon	Homo sapiens	80-83
27533495-16	2016	Six IgE-binding areas, represented by 23 amino acids, account for more than 80% of total IgE binding capacity of Gly m 4.	Glycine	113-116	immunoglobulin heavy constant epsilon	Homo sapiens	4-7
27533495-16	2016	Six IgE-binding areas, represented by 23 amino acids, account for more than 80% of total IgE binding capacity of Gly m 4.	Glycine	113-116	immunoglobulin heavy constant epsilon	Homo sapiens	89-92
27639801-6	2016	A potent intestinal FXR antagonist, glycine-beta-MCA (Gly-MCA), which is resistant to BSH, was developed, which, when administered to HFD-treated mice, mimics the effect of the altered microbiota on HFD-induced metabolic disease.	Glycine	36-43	nuclear receptor subfamily 1, group H, member 4	Mus musculus	20-23
27639801-10	2016	In mouse ileum, because of the presence of endogenous FXR agonists produced in the liver, FXR target genes involved in ceramide synthesis are activated and when Gly-MCA is administered they are repressed, which likely accounts for the decrease in serum ceramides.	Glycine	161-164	nuclear receptor subfamily 1, group H, member 4	Mus musculus	54-57
27702986-5	2016	We show that residue glycine 39 (G39) in Gadd45a is essential for interacting with core histones, opening chromatin and enhancing reprogramming.	Glycine	21-28	growth arrest and DNA-damage-inducible 45 alpha	Mus musculus	41-48
27639801-6	2016	A potent intestinal FXR antagonist, glycine-beta-MCA (Gly-MCA), which is resistant to BSH, was developed, which, when administered to HFD-treated mice, mimics the effect of the altered microbiota on HFD-induced metabolic disease.	Glycine	54-57	nuclear receptor subfamily 1, group H, member 4	Mus musculus	20-23
27807405-5	2016	The potentiation of AMPA receptor function by glycine is antagonized by the inhibition of ERK1/2.	Glycine	46-53	mitogen-activated protein kinase 3	Homo sapiens	90-96
27676255-0	2016	A novel mutation in the fibrinogen gamma-chain 216 Gly&gt;Glu causes hypofibrinogenemia.	Glycine	51-54	fibrinogen gamma chain	Homo sapiens	24-46
26497039-5	2016	Furthermore, GLY differentially modulated the activities of superoxide dismutase, catalase, and glutathione peroxidase depending on the period tested after GLY administration.	Glycine	13-16	catalase	Rattus norvegicus	82-90
27807405-6	2016	In the hippocampal neurons and in the HEK293 cells transfected with different combinations of NMDA receptors, glycine preferentially acts on GluN2A-containing NMDA receptors (GluN2ARs), but not GluN2B-containing NMDA receptors (GluN2BRs), to enhance ERK1/2 phosphorylation independent of the channel activity of GluN2ARs.	Glycine	110-117	mitogen-activated protein kinase 3	Homo sapiens	250-256
27732679-0	2016	Correction: Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain.	Glycine	122-129	twist family bHLH transcription factor 1	Homo sapiens	115-121
27759100-4	2016	Accordingly, we find that spinal cord glycine levels are significantly reduced in Slc7a10-null mice and spontaneous glycinergic postsynaptic currents in motor neurons show substantially diminished amplitudes, demonstrating an essential role for SLC7A10 in glycinergic inhibitory function in the central nervous system.	Glycine	38-45	solute carrier family 7 (cationic amino acid transporter, y+ system), member 10	Mus musculus	82-89
27784961-2	2016	Then, it is promptly transferred to the sodium taurocholate cotransporting polypeptide (NTCP) via the myristoylated N-terminal sequence of pre-S1 region (from Gly-2 to Gly-48, HBV genotype D), and it finally enters the cell by endocytosis.	Glycine	159-162	solute carrier family 10 member 1	Homo sapiens	88-92
27784961-2	2016	Then, it is promptly transferred to the sodium taurocholate cotransporting polypeptide (NTCP) via the myristoylated N-terminal sequence of pre-S1 region (from Gly-2 to Gly-48, HBV genotype D), and it finally enters the cell by endocytosis.	Glycine	168-171	solute carrier family 10 member 1	Homo sapiens	88-92
27761313-5	2016	The substitution of a nonpolar amino acid glycine in wildtype Cx26 at position 45 with a negatively charged glutamic acid (acidic) has previously been shown to interfere with Ca2+ regulation of hemichannel gating and to inhibit the formation of gap junctions, resulting in cell death.	Glycine	42-49	gap junction protein beta 2	Homo sapiens	62-66
27761313-8	2016	Thus, the two oppositely charged amino acids that replace the highly conserved uncharged glycine in p.Gly45Glu and p.Gly45Arg, respectively, produce strikingly different effects on the structure and function of the Cx26 protein.	Glycine	89-96	gap junction protein beta 2	Homo sapiens	215-219
27807405-8	2016	Thus, these results reveal a metabotropic function of GluN2ARs in mediating glycine-induced potentiation of AMPA receptor function via ERK1/2 activation.	Glycine	76-83	mitogen-activated protein kinase 3	Homo sapiens	135-141
27547863-5	2016	Transport uptake of Glycylsarcosine (Gly-sar) by the hPepT1-N562Q variant, but not by other single mutants, was moderately impaired.	Glycine	20-23	solute carrier family 15 member 1	Homo sapiens	53-59
27547863-8	2016	Kinetic studies indicated that the Vmax values for Gly-sar transport by low activity mutants were decreased compared to those of wild-type, which suggested that the cell surface expression and/or turnover rate of hPepT1 mutants was impaired; Km values were unchanged in most cases.	Glycine	51-54	solute carrier family 15 member 1	Homo sapiens	213-219
25721693-7	2016	GLY decreased the secretion of TNF-alpha from the oral cancer CAL 27 cells.	Glycine	0-3	tumor necrosis factor	Homo sapiens	31-40
27694970-2	2016	Here we show that glycine enhances the activation of cell survival-promoting kinase Akt in cultured cortical neurons in which both the channel activity of NMDARs and the glycine receptors are pre-inhibited.	Glycine	18-25	AKT serine/threonine kinase 1	Homo sapiens	84-87
27694970-3	2016	The effect of glycine is reduced by shRNA-mediated knockdown of GluN2A subunit-containing NMDARs (GluN2ARs), suggesting that a non-ionotropic activity of GluN2ARs mediates glycine-induced Akt activation.	Glycine	14-21	AKT serine/threonine kinase 1	Homo sapiens	188-191
27565992-8	2016	Moreover, a single mutation (aspartate to glycine) at amino acid position 54 in M1 [M1(D54G)] was detected after 18 passages in the presence of KR-23502 with a 2-fold increase in 50% effective concentration indicating that this compound has a relatively high genetic barrier to resistance.	Glycine	42-49	myoregulin	Homo sapiens	80-82
27565992-8	2016	Moreover, a single mutation (aspartate to glycine) at amino acid position 54 in M1 [M1(D54G)] was detected after 18 passages in the presence of KR-23502 with a 2-fold increase in 50% effective concentration indicating that this compound has a relatively high genetic barrier to resistance.	Glycine	42-49	myoregulin	Homo sapiens	84-86
27694970-4	2016	In support of this finding, glycine enhances Akt activation in HEK293 cells over-expressing GluN2ARs.	Glycine	28-35	AKT serine/threonine kinase 1	Homo sapiens	45-48
27694970-5	2016	The effect of glycine on Akt activation is sensitive to the antagonist of glycine-GluN1 binding site.	Glycine	14-21	AKT serine/threonine kinase 1	Homo sapiens	25-28
27694970-5	2016	The effect of glycine on Akt activation is sensitive to the antagonist of glycine-GluN1 binding site.	Glycine	74-81	AKT serine/threonine kinase 1	Homo sapiens	25-28
27694970-6	2016	As a functional consequence, glycine protects against excitotoxicity-induced neuronal death through the non-ionotropic activity of GluN2ARs and the neuroprotective effect is attenuated by Akt inhibition.	Glycine	29-36	AKT serine/threonine kinase 1	Homo sapiens	188-191
27694970-7	2016	Thus, this study reveals an unexpected role of glycine in eliciting a non-ionotropic activity of GluN2ARs to confer neuroprotection via Akt activation.	Glycine	47-54	AKT serine/threonine kinase 1	Homo sapiens	136-139
25721693-8	2016	Furthermore, 2000 mug/mL of GLY significantly suppressed TNF-alpha mRNA expression of CAL 27 cells in a time-dependent manner.	Glycine	28-31	tumor necrosis factor	Homo sapiens	57-66
25721693-9	2016	GLY reduced the levels of proteins, including nuclear NF-kappaB (p65 and p50), p-IKK (ser176), p-IkappaB, p-AKT, p-ERK, and nuclear Egr-1 in a time and dose-dependent manner.	Glycine	0-3	nuclear factor kappa B subunit 1	Homo sapiens	54-63
25721693-9	2016	GLY reduced the levels of proteins, including nuclear NF-kappaB (p65 and p50), p-IKK (ser176), p-IkappaB, p-AKT, p-ERK, and nuclear Egr-1 in a time and dose-dependent manner.	Glycine	0-3	nuclear factor kappa B subunit 1	Homo sapiens	73-76
25721693-9	2016	GLY reduced the levels of proteins, including nuclear NF-kappaB (p65 and p50), p-IKK (ser176), p-IkappaB, p-AKT, p-ERK, and nuclear Egr-1 in a time and dose-dependent manner.	Glycine	0-3	AKT serine/threonine kinase 1	Homo sapiens	108-111
25721693-10	2016	GLY also suppressed the NF-kappaB activity and translocation in CAL 27 cells.	Glycine	0-3	nuclear factor kappa B subunit 1	Homo sapiens	24-33
25721693-11	2016	We suggest that GLY might promote the cure of oral cancer through decreasing the level of TNF-alpha cytokine, and these actions were mediated partially through the NF-kappaB, AKT, and ERK-dependent pathways in vitro.	Glycine	16-19	tumor necrosis factor	Homo sapiens	90-99
25721693-11	2016	We suggest that GLY might promote the cure of oral cancer through decreasing the level of TNF-alpha cytokine, and these actions were mediated partially through the NF-kappaB, AKT, and ERK-dependent pathways in vitro.	Glycine	16-19	nuclear factor kappa B subunit 1	Homo sapiens	164-173
25721693-11	2016	We suggest that GLY might promote the cure of oral cancer through decreasing the level of TNF-alpha cytokine, and these actions were mediated partially through the NF-kappaB, AKT, and ERK-dependent pathways in vitro.	Glycine	16-19	AKT serine/threonine kinase 1	Homo sapiens	175-178
25721693-11	2016	We suggest that GLY might promote the cure of oral cancer through decreasing the level of TNF-alpha cytokine, and these actions were mediated partially through the NF-kappaB, AKT, and ERK-dependent pathways in vitro.	Glycine	16-19	mitogen-activated protein kinase 1	Homo sapiens	184-187
27556926-0	2016	Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain.	Glycine	110-117	twist family bHLH transcription factor 1	Homo sapiens	103-109
27296115-7	2016	It is concluded that BDNF effect upon glycine uptake into glycinergic nerve terminals requires the activation of the TrkB-FL receptor and its canonical signalling pathways and occurs by inhibiting GlyT2 membrane incorporation.	Glycine	38-45	neurotrophic receptor tyrosine kinase 2	Rattus norvegicus	117-121
27476175-4	2016	Herein we describe the biochemical and molecular characterization of yeast Hem25p and human SLC25A38, providing evidence that they are mitochondrial carriers for glycine.	Glycine	162-169	Hem25p	Saccharomyces cerevisiae S288C	75-81
27476175-7	2016	Our results identify new proteins in the heme biosynthetic pathway and demonstrate that Hem25p and its human orthologue SLC25A38 are the main mitochondrial glycine transporters required for heme synthesis, providing definitive evidence of their previously proposed glycine transport function.	Glycine	156-163	Hem25p	Saccharomyces cerevisiae S288C	88-94
27739310-5	2016	One of these molecules is glycine-N-methyltransferase (GNMT), an enzyme that plays a pivotal role in the biochemical conversion of glycine to sarcosine.	Glycine	26-33	glycine N-methyltransferase	Homo sapiens	55-59
27502273-8	2016	Using protease cleavage-predicting software and site-directed mutagenesis, we identified that calpain-1 cleaves hERG at position Gly-603 in the S5-pore linker of hERG.	Glycine	129-132	ETS transcription factor ERG	Homo sapiens	112-116
27502273-8	2016	Using protease cleavage-predicting software and site-directed mutagenesis, we identified that calpain-1 cleaves hERG at position Gly-603 in the S5-pore linker of hERG.	Glycine	129-132	ETS transcription factor ERG	Homo sapiens	162-166
27618671-4	2016	NAM binding causes displacement of a valine in GluN2A and the resulting steric effects can be mitigated by the transition from glycine bound to apo state of the GluN1 LBD.	Glycine	127-134	SH3 and cysteine rich domain 3	Homo sapiens	0-3
27618671-4	2016	NAM binding causes displacement of a valine in GluN2A and the resulting steric effects can be mitigated by the transition from glycine bound to apo state of the GluN1 LBD.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	47-53
27618671-4	2016	NAM binding causes displacement of a valine in GluN2A and the resulting steric effects can be mitigated by the transition from glycine bound to apo state of the GluN1 LBD.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	161-166
27533248-2	2016	P45 is a hybrid peptide composed of an Arg-Gly-Asp motif linked to the human matrilin-1 C-terminal domain by a serine linker.	Glycine	43-46	nuclear factor, erythroid 2	Homo sapiens	0-3
27585677-4	2016	sPLA2 with glycine and serine at the 80th positions and the M-type receptor were modelled.	Glycine	11-18	phospholipase A2 group X	Homo sapiens	0-5
27508457-8	2016	BPS changed the structure and the activity of CAT through binding to the Gly 117 residue on the substrate channel of the enzyme.	Glycine	73-76	catalase	Mus musculus	46-49
27556926-6	2016	Through sequence comparison we demonstrate that the Twist protein family ancestor was "Twist2-like" and the two glycine-rich regions found in Twist1 sequences were acquired late in evolution, apparently not at the same time.	Glycine	112-119	twist family bHLH transcription factor 1	Homo sapiens	142-148
27556926-9	2016	Detailed examination of the glycine-rich regions in the N-terminus of Twist1 demonstrate that the first region is completely aliphatic while the second region contains some polar residues that could be subject to post-translational modification.	Glycine	28-35	twist family bHLH transcription factor 1	Homo sapiens	70-76
27316830-4	2016	An affinity tag comprised of a proline, a glycine and eight histidines was introduced into the C-terminal end of hPGHS-2.	Glycine	42-49	prostaglandin-endoperoxide synthase 2	Homo sapiens	113-120
27267252-1	2016	N-Myristoyltransferase (NMT) covalently attaches a C14 fatty acid to the N-terminal glycine of proteins and has been proposed as a therapeutic target in cancer.	Glycine	84-91	N-myristoyltransferase 1	Homo sapiens	0-22
27267252-1	2016	N-Myristoyltransferase (NMT) covalently attaches a C14 fatty acid to the N-terminal glycine of proteins and has been proposed as a therapeutic target in cancer.	Glycine	84-91	N-myristoyltransferase 1	Homo sapiens	24-27
27207556-9	2016	Finally, a significant positive relationship exists between insulin and GlyR, because insulin enhances the glycine-activated current in a phosphoinositide 3-kinase-dependent manner, a positive feedback loop that we find is completely lost in beta-cells from donors with T2D.	Glycine	107-114	insulin	Homo sapiens	86-93
27225947-0	2016	Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.	Glycine	0-7	AKT serine/threonine kinase 1	Homo sapiens	65-68
27225947-0	2016	Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.	Glycine	0-7	mechanistic target of rapamycin kinase	Homo sapiens	69-73
27225947-0	2016	Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.	Glycine	0-7	forkhead box O1	Homo sapiens	74-79
27225947-7	2016	Glycine also resulted in decreased mRNA expression of muscle atrophy F-box (MAFbx) and muscle RING finger 1 (MuRF1) in gastrocnemius muscle.	Glycine	0-7	tripartite motif containing 63	Homo sapiens	109-114
27225947-8	2016	In addition, glycine restored the phosphorylation of Akt, mammalian target of rapamycin (mTOR), eukaryotic initiation factor 4E binding protein 1 (4E-BP1), and Forkhead Box O 1 (FOXO1) in gastrocnemius or LD muscles.	Glycine	13-20	AKT serine/threonine kinase 1	Homo sapiens	53-56
27225947-8	2016	In addition, glycine restored the phosphorylation of Akt, mammalian target of rapamycin (mTOR), eukaryotic initiation factor 4E binding protein 1 (4E-BP1), and Forkhead Box O 1 (FOXO1) in gastrocnemius or LD muscles.	Glycine	13-20	mechanistic target of rapamycin kinase	Homo sapiens	58-87
27225947-8	2016	In addition, glycine restored the phosphorylation of Akt, mammalian target of rapamycin (mTOR), eukaryotic initiation factor 4E binding protein 1 (4E-BP1), and Forkhead Box O 1 (FOXO1) in gastrocnemius or LD muscles.	Glycine	13-20	mechanistic target of rapamycin kinase	Homo sapiens	89-93
27225947-8	2016	In addition, glycine restored the phosphorylation of Akt, mammalian target of rapamycin (mTOR), eukaryotic initiation factor 4E binding protein 1 (4E-BP1), and Forkhead Box O 1 (FOXO1) in gastrocnemius or LD muscles.	Glycine	13-20	forkhead box O1	Homo sapiens	160-176
27207556-0	2016	A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human beta-Cells and Is Impaired in Type 2 Diabetes.	Glycine	2-9	insulin	Homo sapiens	10-17
27207556-0	2016	A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human beta-Cells and Is Impaired in Type 2 Diabetes.	Glycine	2-9	insulin	Homo sapiens	51-58
27207556-6	2016	beta-Cells exhibit significant glycine-induced Cl(-) currents that promote membrane depolarization, Ca(2+) entry, and insulin secretion from beta-cells from donors without T2D.	Glycine	31-38	insulin	Homo sapiens	118-125
27207556-9	2016	Finally, a significant positive relationship exists between insulin and GlyR, because insulin enhances the glycine-activated current in a phosphoinositide 3-kinase-dependent manner, a positive feedback loop that we find is completely lost in beta-cells from donors with T2D.	Glycine	107-114	insulin	Homo sapiens	60-67
27225947-8	2016	In addition, glycine restored the phosphorylation of Akt, mammalian target of rapamycin (mTOR), eukaryotic initiation factor 4E binding protein 1 (4E-BP1), and Forkhead Box O 1 (FOXO1) in gastrocnemius or LD muscles.	Glycine	13-20	forkhead box O1	Homo sapiens	178-183
27225947-9	2016	Furthermore, glycine resulted in decreased plasma tumor necrosis factor-alpha (TNF-alpha) concentration and muscle TNF-alpha mRNA abundance.	Glycine	13-20	tumor necrosis factor	Homo sapiens	50-77
27225947-9	2016	Furthermore, glycine resulted in decreased plasma tumor necrosis factor-alpha (TNF-alpha) concentration and muscle TNF-alpha mRNA abundance.	Glycine	13-20	tumor necrosis factor	Homo sapiens	79-88
27225947-9	2016	Furthermore, glycine resulted in decreased plasma tumor necrosis factor-alpha (TNF-alpha) concentration and muscle TNF-alpha mRNA abundance.	Glycine	13-20	tumor necrosis factor	Homo sapiens	115-124
27225947-12	2016	The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.	Glycine	24-31	AKT serine/threonine kinase 1	Homo sapiens	86-89
27225947-12	2016	The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.	Glycine	24-31	mechanistic target of rapamycin kinase	Homo sapiens	90-94
27225947-12	2016	The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.	Glycine	24-31	forkhead box O1	Homo sapiens	95-100
27098371-10	2016	We performed single cell electrophysiology, immunocytochemistry and confocal microscopy and suggest that GABA co-release may speed the decay of glycine responses altering both temporal precision and signal integration in SOD1(G93A) developing networks at the postsynaptic site.	Glycine	144-151	superoxide dismutase 1, soluble	Mus musculus	221-225
27270213-6	2016	Single-channel patch-clamp and four-channel fluorescence measurement are recorded simultaneously to get correlation among electrical on and off states, optically determined conformational open and closed states by FRET, and binding-unbinding states of the glycine ligand by anisotropy measurement at the ligand binding domain of GluN1 subunit.	Glycine	256-263	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	329-334
27338790-5	2016	Crystallographic studies of the CRBN-DDB1-CC-885-GSPT1 complex reveal that GSPT1 binds to cereblon through a surface turn containing a glycine residue at a key position, interacting with both CC-885 and a "hotspot" on the cereblon surface.	Glycine	135-142	cereblon	Homo sapiens	32-36
27338790-5	2016	Crystallographic studies of the CRBN-DDB1-CC-885-GSPT1 complex reveal that GSPT1 binds to cereblon through a surface turn containing a glycine residue at a key position, interacting with both CC-885 and a "hotspot" on the cereblon surface.	Glycine	135-142	G1 to S phase transition 1	Homo sapiens	49-54
27338790-5	2016	Crystallographic studies of the CRBN-DDB1-CC-885-GSPT1 complex reveal that GSPT1 binds to cereblon through a surface turn containing a glycine residue at a key position, interacting with both CC-885 and a "hotspot" on the cereblon surface.	Glycine	135-142	G1 to S phase transition 1	Homo sapiens	75-80
27338790-5	2016	Crystallographic studies of the CRBN-DDB1-CC-885-GSPT1 complex reveal that GSPT1 binds to cereblon through a surface turn containing a glycine residue at a key position, interacting with both CC-885 and a "hotspot" on the cereblon surface.	Glycine	135-142	cereblon	Homo sapiens	90-98
27187177-4	2016	The acute (6 h) and chronic (11 d) proliferative responses to long-acting human (Gly(2))GLP-2 in the crypt TA zone, but not in the active or reserve stem cell zones, were both impaired by Bmi-1 haploinsufficiency.	Glycine	81-84	glucagon	Homo sapiens	88-93
27055186-7	2016	The free cysteine and glycine treatment reduced TNF-alpha in sow-fed animals (P &lt; 0.05).	Glycine	22-29	tumor necrosis factor	Homo sapiens	48-57
27355841-2	2016	Glycine N-methyltransferase (GNMT), a member of the family that acts on small metabolites as the substrate, catalyzes methyl transfer from S-adenosyl-l-methionine (AdoMet) to glycine to form S-adenosyl-l-homocysteine and sarcosine.	Glycine	175-182	glycine N-methyltransferase	Homo sapiens	0-27
27355841-2	2016	Glycine N-methyltransferase (GNMT), a member of the family that acts on small metabolites as the substrate, catalyzes methyl transfer from S-adenosyl-l-methionine (AdoMet) to glycine to form S-adenosyl-l-homocysteine and sarcosine.	Glycine	175-182	glycine N-methyltransferase	Homo sapiens	29-33
26494047-8	2016	In addition, four novel ACE inhibitory peptides were isolated, and their amino acids sequences were identified as Val-Gly-Pro-Tyr, Phe-Thr-Tyr-Val-Pro-Gly, Phe-Thr-Tyr-Val-Pro-Gly-Ala and Phe-Gln-Ala-Val-Trp-Ala-Gly, respectively.	Glycine	118-121	angiotensin I converting enzyme	Homo sapiens	24-27
27358718-7	2016	The combined network shows that glycolytic enzymes are linked to miRs via p53, c-MYC, HIF1alpha, whereas the genes in serine, glycine and one carbon metabolism are regulated via the c-MYC, as well as other regulatory organization that cannot be observed by investigating individual miRs, TFs, and target genes.	Glycine	126-133	tumor protein p53	Homo sapiens	74-77
27178435-2	2016	NMDA receptor neurotransmission can be enhanced through inhibition of glycine reuptake by the glycine transporter type 1 (GlyT1).	Glycine	70-77	solute carrier family 6 member 9	Homo sapiens	94-120
27178435-2	2016	NMDA receptor neurotransmission can be enhanced through inhibition of glycine reuptake by the glycine transporter type 1 (GlyT1).	Glycine	70-77	solute carrier family 6 member 9	Homo sapiens	122-127
26768609-2	2016	The NGR (asparagine-glycine-arginine)-containing peptides can specifically bind to CD13 (Aminopeptidase N) receptor which is overexpressed in angiogenic blood vessels and tumor cells.	Glycine	20-27	reticulon 4 receptor	Mus musculus	4-7
27058626-2	2016	The Gly co-treatment significantly increased the cell viability, inhibited the expression of phospho-Nuclear Factor kappa B (p-NF-kB) and caspase-3 and reduced the oxidative stress in ethanol-treated SH-SY5Y cells in a PI3K-dependent manner.	Glycine	4-7	caspase 3	Homo sapiens	138-147
27010645-5	2016	KEY RESULTS: Six pairs of positions in GluN1/GluN2B significantly interacted to regulate ethanol inhibition: Gly(638) /Met(824) , Gly(638) /Leu(825) , Phe(639) /Leu(825) , Phe(639) /Gly(826) , Met(818) /Phe(637) and Val(820) /Phe(637) .	Glycine	109-112	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	39-44
27010645-5	2016	KEY RESULTS: Six pairs of positions in GluN1/GluN2B significantly interacted to regulate ethanol inhibition: Gly(638) /Met(824) , Gly(638) /Leu(825) , Phe(639) /Leu(825) , Phe(639) /Gly(826) , Met(818) /Phe(637) and Val(820) /Phe(637) .	Glycine	130-133	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	39-44
27010645-5	2016	KEY RESULTS: Six pairs of positions in GluN1/GluN2B significantly interacted to regulate ethanol inhibition: Gly(638) /Met(824) , Gly(638) /Leu(825) , Phe(639) /Leu(825) , Phe(639) /Gly(826) , Met(818) /Phe(637) and Val(820) /Phe(637) .	Glycine	130-133	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	39-44
26577016-7	2016	Glycine substitution in the GluN1 S2-M4 region significantly decreased glutamate potency of GluN1(A804G)/GluN2A receptors, while GluN1(A804G)/GluN2B receptors exhibited no change in glutamate sensitivity.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	28-33
27058626-4	2016	Gly co-treatment stimulated the PI3K/Akt signaling pathway to limit the ethanol induced reactive oxygen species (ROS) production in the developing rat brain.	Glycine	0-3	AKT serine/threonine kinase 1	Rattus norvegicus	37-40
27058626-6	2016	Additionally, the Gly treatment upregulated antiapoptotic Bcl-2 proteins and prevented ethanol-induced neurodegeneration as assessed by Fluoro-Jade-B (FJB) and Nissl staining.	Glycine	18-21	BCL2, apoptosis regulator	Rattus norvegicus	58-63
27058626-7	2016	Furthermore, the Gly administration caused significant reduction in the ethanol-induced neuroinflammation by inhibiting the expression of inflammatory markers such as p-NF-kB, cyclooxygenase 2 (COX2) and tumor necrosis factor-alpha (TNF-alpha) and reversed the ethanol-induced synaptic protein markers expression.	Glycine	17-20	tumor necrosis factor	Rattus norvegicus	204-231
27058626-7	2016	Furthermore, the Gly administration caused significant reduction in the ethanol-induced neuroinflammation by inhibiting the expression of inflammatory markers such as p-NF-kB, cyclooxygenase 2 (COX2) and tumor necrosis factor-alpha (TNF-alpha) and reversed the ethanol-induced synaptic protein markers expression.	Glycine	17-20	tumor necrosis factor	Rattus norvegicus	233-242
27222287-3	2016	We show that N-terminal glycine myristoylation causes LANCL2 localization to the plasmamembrane and to cytoplasmic membrane vesicles, where it interacts with the alpha subunit of a Gi protein and starts the ABA signaling pathway via activation of adenylate cyclase.	Glycine	24-31	LanC like 2	Homo sapiens	54-60
26577016-7	2016	Glycine substitution in the GluN1 S2-M4 region significantly decreased glutamate potency of GluN1(A804G)/GluN2A receptors, while GluN1(A804G)/GluN2B receptors exhibited no change in glutamate sensitivity.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	92-97
26577016-7	2016	Glycine substitution in the GluN1 S2-M4 region significantly decreased glutamate potency of GluN1(A804G)/GluN2A receptors, while GluN1(A804G)/GluN2B receptors exhibited no change in glutamate sensitivity.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	105-111
26577016-7	2016	Glycine substitution in the GluN1 S2-M4 region significantly decreased glutamate potency of GluN1(A804G)/GluN2A receptors, while GluN1(A804G)/GluN2B receptors exhibited no change in glutamate sensitivity.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	92-97
27027728-10	2016	CONCLUSIONS: Data from our study suggest that the beta adrenoreceptor Gly 49 allele of the beta1 -adrenergic receptor Ser(49) Gly polymorphisms may increase the risk of ICD shock in patients with heart failure, independent of beta-blocker dosage.	Glycine	70-73	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	91-96
27027728-10	2016	CONCLUSIONS: Data from our study suggest that the beta adrenoreceptor Gly 49 allele of the beta1 -adrenergic receptor Ser(49) Gly polymorphisms may increase the risk of ICD shock in patients with heart failure, independent of beta-blocker dosage.	Glycine	126-129	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	91-96
27016726-3	2016	We provide evidence that the N-acylglycines are formed by a long-chain specific glycine-conjugating enzyme, glycine N-acyltransferase-like 3 (GLYATL3).	Glycine	35-42	glycine-N-acyltransferase-like 3	Mus musculus	108-140
27242518-0	2016	Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Abeta Oligomers in Cells.	Glycine	0-8	amyloid beta precursor protein	Homo sapiens	87-92
27242518-6	2016	Glycine-to-leucine mutations of these motifs were previously shown to affect APP processing and Abeta production in cells.	Glycine	0-7	amyloid beta precursor protein	Homo sapiens	96-101
27242518-10	2016	By a point-mutation approach, we demonstrate that glycine-to-leucine mutations in the G(29)XXXG(33) and G(38)XXXA(42) motifs dramatically affect the Abeta oligomerization process.	Glycine	50-57	amyloid beta precursor protein	Homo sapiens	149-154
27016726-3	2016	We provide evidence that the N-acylglycines are formed by a long-chain specific glycine-conjugating enzyme, glycine N-acyltransferase-like 3 (GLYATL3).	Glycine	35-42	glycine-N-acyltransferase-like 3	Mus musculus	142-149
26832798-7	2016	Our data show that long-term exposure of cells to SCH772984 leads to acquired resistance, attributable to a mutation of glycine to aspartic acid (G(186D)) in the DFG motif of ERK1.	Glycine	120-127	mitogen-activated protein kinase 3	Homo sapiens	175-179
26662804-3	2016	ATG4B, a cysteine protease required for autophagy, cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine which is necessary for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to autophagosome precursor membranes.	Glycine	132-139	GABA type A receptor associated protein like 1	Homo sapiens	88-92
26662804-3	2016	ATG4B, a cysteine protease required for autophagy, cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine which is necessary for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to autophagosome precursor membranes.	Glycine	132-139	GABA type A receptor associated protein like 1	Homo sapiens	163-167
26996083-0	2016	Segregated Glycine-Glutamate Co-transmission from vGluT3 Amacrine Cells to Contrast-Suppressed and Contrast-Enhanced Retinal Circuits.	Glycine	11-18	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	Mus musculus	50-56
26996083-3	2016	Here we report Ca(2+)-dependent co-release of a new combination of inhibitory and excitatory neurotransmitters, namely, glycine and glutamate, by the vGluT3-expressing amacrine cell (GAC) in the mouse retina.	Glycine	120-127	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	Mus musculus	150-156
26661034-2	2016	Here we report the development of an advanced procedure for preparation of the target amino acid via two-step SN2 and SN2" alkylation of novel axially chiral nucleophilic glycine equivalent.	Glycine	171-178	solute carrier family 38 member 5	Homo sapiens	110-113
26661034-2	2016	Here we report the development of an advanced procedure for preparation of the target amino acid via two-step SN2 and SN2" alkylation of novel axially chiral nucleophilic glycine equivalent.	Glycine	171-178	solute carrier family 38 member 5	Homo sapiens	118-121
26975021-10	2016	Moreover, AGL loss determines augmented levels of the serine-to-glycine enzyme serine hydroxymethyltransferase-2 (SHMT2), resulting in an increased glycine and purine ring of nucleotides synthesis, thus supporting cells proliferation.	Glycine	64-71	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	10-13
26975021-10	2016	Moreover, AGL loss determines augmented levels of the serine-to-glycine enzyme serine hydroxymethyltransferase-2 (SHMT2), resulting in an increased glycine and purine ring of nucleotides synthesis, thus supporting cells proliferation.	Glycine	148-155	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	10-13
27034754-0	2016	Effect of glycine pretreatment on the shear bond strength of a CAD/CAM resin nano ceramic material to dentin.	Glycine	10-17	calmodulin	Bos taurus	67-70
27034754-1	2016	BACKGROUND: The purpose of this study was to evaluate the effect of glycine pretreatment on the shear bond strength between dentin and a CAD/CAM resin nano ceramic material (LavaTM Ultimate Restorative), bonded together with adhesive cements using three different luting protocols (total-etch; self-etch; self-adhesive).	Glycine	68-75	calmodulin	Bos taurus	141-144
26758691-1	2016	Primary hyperoxaluria type 1 (PH1) is an autosomal recessive, metabolic disorder caused by mutations of alanine-glyoxylate aminotransferase (AGT), a key hepatic enzyme in the detoxification of glyoxylate arising from multiple normal metabolic pathways to glycine.	Glycine	255-262	alanine-glyoxylate aminotransferase	Mus musculus	104-139
26758691-1	2016	Primary hyperoxaluria type 1 (PH1) is an autosomal recessive, metabolic disorder caused by mutations of alanine-glyoxylate aminotransferase (AGT), a key hepatic enzyme in the detoxification of glyoxylate arising from multiple normal metabolic pathways to glycine.	Glycine	255-262	alanine-glyoxylate aminotransferase	Mus musculus	141-144
26548749-7	2016	The TLR2 Ins/Del genotype is associated with tumor evolution to stage (III+IV) [p = 0.003; OR: 3.00 (1.22-7.35)] and the genotypes Gly/Gly and Asp/Gly+Gly/Gly and Gly allele of TLR 4 are implicated in tumor evolution to the advanced stages.	Glycine	131-134	toll like receptor 2	Homo sapiens	4-8
26548749-7	2016	The TLR2 Ins/Del genotype is associated with tumor evolution to stage (III+IV) [p = 0.003; OR: 3.00 (1.22-7.35)] and the genotypes Gly/Gly and Asp/Gly+Gly/Gly and Gly allele of TLR 4 are implicated in tumor evolution to the advanced stages.	Glycine	135-138	toll like receptor 2	Homo sapiens	4-8
26548749-7	2016	The TLR2 Ins/Del genotype is associated with tumor evolution to stage (III+IV) [p = 0.003; OR: 3.00 (1.22-7.35)] and the genotypes Gly/Gly and Asp/Gly+Gly/Gly and Gly allele of TLR 4 are implicated in tumor evolution to the advanced stages.	Glycine	135-138	toll like receptor 2	Homo sapiens	4-8
26548749-7	2016	The TLR2 Ins/Del genotype is associated with tumor evolution to stage (III+IV) [p = 0.003; OR: 3.00 (1.22-7.35)] and the genotypes Gly/Gly and Asp/Gly+Gly/Gly and Gly allele of TLR 4 are implicated in tumor evolution to the advanced stages.	Glycine	135-138	toll like receptor 2	Homo sapiens	4-8
26548749-7	2016	The TLR2 Ins/Del genotype is associated with tumor evolution to stage (III+IV) [p = 0.003; OR: 3.00 (1.22-7.35)] and the genotypes Gly/Gly and Asp/Gly+Gly/Gly and Gly allele of TLR 4 are implicated in tumor evolution to the advanced stages.	Glycine	135-138	toll like receptor 2	Homo sapiens	4-8
26548749-7	2016	The TLR2 Ins/Del genotype is associated with tumor evolution to stage (III+IV) [p = 0.003; OR: 3.00 (1.22-7.35)] and the genotypes Gly/Gly and Asp/Gly+Gly/Gly and Gly allele of TLR 4 are implicated in tumor evolution to the advanced stages.	Glycine	135-138	toll like receptor 2	Homo sapiens	4-8
27117808-3	2016	We present a novel mutation in codon 137 within AVPR2 with substitution of glycine for arginine in male dizygotic twins.	Glycine	75-82	arginine vasopressin receptor 2	Homo sapiens	48-53
27029941-11	2016	Compared with controls, 1.0 mmol glycine/L reduced the protein abundance of ZO-1 by 20% at 8 h (P &lt; 0.05), but 0.25 mmol glycine/L had no effect.	Glycine	33-40	tight junction protein 1	Homo sapiens	76-80
27029941-13	2016	Interestingly, 1 mmol glycine/L promoted the distribution of claudin-4 and claudin-7 to the cytosol and nucleus, and the localization of ZO-3 to the plasma membranes, while decreasing the distribution of ZO-1 at cell-cell contact sites, compared with control cells.	Glycine	22-29	claudin 4	Homo sapiens	61-70
27029941-13	2016	Interestingly, 1 mmol glycine/L promoted the distribution of claudin-4 and claudin-7 to the cytosol and nucleus, and the localization of ZO-3 to the plasma membranes, while decreasing the distribution of ZO-1 at cell-cell contact sites, compared with control cells.	Glycine	22-29	tight junction protein 1	Homo sapiens	204-208
27004562-6	2016	A novel c.1176_1178delTCT mutation caused deletion of a glycine in exon 9 of LAMB2, and another mutation c.4923 + 2 T &gt; G led to a splicing error.	Glycine	56-63	laminin subunit beta 2	Homo sapiens	77-82
26919468-10	2016	Our recent biochemical studies showed that the archael Thi4 orthologs use nicotinamide adenine dinucleotide, glycine, and free sulfide to form the thiamin thiazole in an iron-dependent reaction [Eser, B., Zhang, X., Chanani, P. K., Begley, T. P., and Ealick, S. E. (2016) J.	Glycine	109-116	thiamine thiazole synthase	Saccharomyces cerevisiae S288C	55-59
26912818-5	2016	Glycine and proline only marginally stimulated the IL-8 production by IL-1beta-stimulated gingival fibroblast, whereas glycine dose-dependently inhibited the nitric oxide production by lipopolysaccharide-stimulated mouse macrophage-like RAW264.7 cells.	Glycine	0-7	interleukin 1 beta	Mus musculus	70-78
26867113-2	2016	Glycine (Gly), glutamic acid (Glu), and histidine (His) with different isoelectric points were chosen as representative amino acid candidates to synthesize corresponding amino acid-DTC compounds through mixing with carbon disulfide (CS2), respectively.	Glycine	0-7	chorionic somatomammotropin hormone 2	Homo sapiens	233-236
26867113-2	2016	Glycine (Gly), glutamic acid (Glu), and histidine (His) with different isoelectric points were chosen as representative amino acid candidates to synthesize corresponding amino acid-DTC compounds through mixing with carbon disulfide (CS2), respectively.	Glycine	0-3	chorionic somatomammotropin hormone 2	Homo sapiens	233-236
26563333-6	2016	Activity of alkaline phosphatase (ALP) and phosphorylation of extracellular-signal-regulated kinase were increased by glycine in MG-63 cells.	Glycine	118-125	alkaline phosphatase, placental	Homo sapiens	12-32
26563333-6	2016	Activity of alkaline phosphatase (ALP) and phosphorylation of extracellular-signal-regulated kinase were increased by glycine in MG-63 cells.	Glycine	118-125	alkaline phosphatase, placental	Homo sapiens	34-37
26563333-12	2016	Glycine significantly increased the ALP activity in OVX mice.	Glycine	0-7	alkaline phosphatase, placental	Homo sapiens	36-39
27000430-3	2016	Uniquely within the NMDA receptor family, GluN1/GluN3 receptors produce glycine-gated deeply desensitising currents that are insensitive to glutamate and NMDA; these currents remain poorly characterised and their cellular functions are unknown.	Glycine	72-79	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	42-47
27000430-4	2016	Here, we show that extracellular acidification strongly potentiated glycine-gated currents from recombinant GluN1/GluN3A receptors, with half-maximal effect in the physiologic pH range.	Glycine	68-75	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	108-113
26924013-6	2016	Cell experiments also showed that the designed tripeptide and Gly-Sar were transported across Caco-2 cell via PepT1, whereas the tetra- and pentapeptides were transported through the paracellular tight-junction pathway.	Glycine	62-65	solute carrier family 15 member 1	Homo sapiens	110-115
27241643-8	2016	A G&gt;A substitution at nucleotide 1243 in exon 8 that changes glycine (GGT) to serine (AGT) was observed in most of our patients.	Glycine	64-71	angiotensinogen	Homo sapiens	89-92
26856188-0	2016	Tc-99m Glu-Cys-Gly-His-Gly-Lys (ECG-HGK), a novel Tc-99m labeled hexapeptide for molecular tumor imaging.	Glycine	15-18	mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens	36-39
26856188-0	2016	Tc-99m Glu-Cys-Gly-His-Gly-Lys (ECG-HGK), a novel Tc-99m labeled hexapeptide for molecular tumor imaging.	Glycine	23-26	mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens	36-39
26824641-6	2016	Both AMPA supplementation and elevated glycine decreased the mRNA abundance of SHMT2 and tumor protein p53 (TP53), which is activated in response to cellular stress, compared to controls (P &lt;= 0.02).	Glycine	39-46	tumor protein p53	Homo sapiens	103-106
26824641-6	2016	Both AMPA supplementation and elevated glycine decreased the mRNA abundance of SHMT2 and tumor protein p53 (TP53), which is activated in response to cellular stress, compared to controls (P &lt;= 0.02).	Glycine	39-46	tumor protein p53	Homo sapiens	108-112
26614892-7	2016	The enzyme was used to modify glycine-extended A22(G)-B31(K)-B32(R) human insulin analogue (GKR).	Glycine	30-37	insulin	Homo sapiens	74-81
26824641-3	2016	Genes involved in glycine transport (SLC6A9), glycine metabolism (GLDC, GCSH, DLD, and AMT), and serine metabolism (PSAT1, PSPH, and PHGDH) were differentially expressed.	Glycine	18-25	solute carrier family 6 member 9	Homo sapiens	37-43
26824641-4	2016	Addition of 10 mM glycine to the culture medium (currently containing 0.1 mM) reduced the abundance of SLC6A9 transcript and increased total cell number, primarily in the trophectoderm lineage (P = 0.003); this was likely by decreasing the percentage of apoptotic nuclei.	Glycine	18-25	solute carrier family 6 member 9	Homo sapiens	103-109
26859063-0	2016	The Major Soybean Allergen Gly m Bd 28K Induces Hypersensitivity Reactions in Mice Sensitized to Cow"s Milk Proteins.	Glycine	27-30	Weaning weight-maternal milk	Bos taurus	103-107
26859063-2	2016	In this work, we analyzed if Gly m Bd 28K/P28, one of the major soybean allergens, is a cross-reactive allergen with cow milk proteins (CMP).	Glycine	29-32	Weaning weight-maternal milk	Bos taurus	121-125
27158326-4	2016	Results from Q-PCR and ELISA study showed that compareaded with control, TREM-1 is upregulated and TREM-2 is downregulated respectively in 4 and 8-week NASH model (TREM-1: p &lt; 0.001; TREM-2: p &lt; 0.001).Compared with HFO group, HFOG group with an extra 5% Glycine into the diet of NASH, we found that all model liver pathologic and serum indexes ameliorated in this group.	Glycine	261-268	triggering receptor expressed on myeloid cells 2	Homo sapiens	99-105
26910427-3	2016	Orthograde coupling was previously shown to be ablated by a glycine for glutamate substitution at RyR1 position 4242.	Glycine	60-67	ryanodine receptor 1	Homo sapiens	98-102
26677223-7	2016	These studies reveal a novel rheological strategy in which the incorporation of a single glycine within the GPIbalpha binding interface of normal VWF enhances the probability of local unfolding that enables the A1 domain to conformationally adapt to shear flow while maintaining its overall native structure.	Glycine	89-96	von Willebrand factor	Homo sapiens	146-149
26780688-7	2016	In addition to glycine, which was previously reported to selectively accelerate hASRGL1 cleavage, we identified several novel small molecule activators that also promote intramolecular processing.	Glycine	15-22	asparaginase and isoaspartyl peptidase 1	Homo sapiens	80-87
27158326-0	2016	Ameliorative effects of glycine in an experimental nonalcoholic steatohepatitis and its correlation between TREM-1 and TREM-2.	Glycine	24-31	triggering receptor expressed on myeloid cells 2	Homo sapiens	119-125
26902152-3	2016	Here we reported the first methyltransferase, SET7/9 (KMT7), capable of methylating YY1 at two highly conserved lysine (K) residues, K173 and K411, located in two distinct domains, one in the central glycine-rich region and the other in the very carboxyl-terminus.	Glycine	200-207	YY1 transcription factor	Homo sapiens	84-87
27158326-7	2016	Besides, using multiple-stepwise regression analysis, we found that the ameliorative effects of glycine in HFOG was mainly related to its counteraction of PC III, TREM-1 and upregulation of TREM-2.	Glycine	96-103	triggering receptor expressed on myeloid cells 2	Homo sapiens	190-196
26792730-7	2016	Our data suggest that the Gly(219)-Pro-Tyr motif in the human CrkII linker region serves as the recognition and isomerization site of PPIases, and raise the possibility that CsA and FK506 might interfere with selected effector T cell functions via a CrkII-, but not CrkI-dependent mechanisms.	Glycine	26-29	CRK proto-oncogene, adaptor protein	Homo sapiens	62-67
26792730-7	2016	Our data suggest that the Gly(219)-Pro-Tyr motif in the human CrkII linker region serves as the recognition and isomerization site of PPIases, and raise the possibility that CsA and FK506 might interfere with selected effector T cell functions via a CrkII-, but not CrkI-dependent mechanisms.	Glycine	26-29	CRK proto-oncogene, adaptor protein	Homo sapiens	250-255
26621918-1	2016	The covalent attachment of a 14-carbon aliphatic tail on a glycine residue of nascent translated peptide chains is catalyzed in human cells by two N-myristoyltransferase (NMT) enzymes using the rare myristoyl-CoA (C(14)-CoA) molecule as fatty acid donor.	Glycine	59-66	N-myristoyltransferase 1	Homo sapiens	147-169
26621918-1	2016	The covalent attachment of a 14-carbon aliphatic tail on a glycine residue of nascent translated peptide chains is catalyzed in human cells by two N-myristoyltransferase (NMT) enzymes using the rare myristoyl-CoA (C(14)-CoA) molecule as fatty acid donor.	Glycine	59-66	N-myristoyltransferase 1	Homo sapiens	171-174
26661043-4	2016	Here, we investigate the pharmacology of the orthosteric binding site in GluD2 by examining the activity of analogs of D-Ser and GluN1 glycine site competitive antagonists at GluD2 receptors containing the lurcher mutation (GluD2(LC)), which promotes spontaneous channel activation.	Glycine	135-142	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	129-134
26996629-7	2016	Gly in MS rats decreased body weight, intra-abdominal adipose tissue, adipocyte hypertrophy, blood pressure, triglycerides, insulin, HOMA-IR index, leptin, total fatty acids, non-esterified fatty acids and LPL activity.	Glycine	0-3	lipoprotein lipase	Rattus norvegicus	206-209
26717205-3	2016	Results showed that all novel GP(Me)X tripeptides are stable in human plasma (t1/2 &gt; 51 h) and that GP(Me)H - generating stable intramolecular H-bond in a C11-turn by interaction of His imidazole ring and Gly carbonyl group - restored physiological levels of nitric oxide deriving from neuronal NOS (nNOS) activity, thus preventing the inflammatory response by suppression of the NF-kB activity and, consequently, the expression of inflammatory genes such as inducibile NOS (iNOS).	Glycine	208-211	nitric oxide synthase 2	Homo sapiens	478-482
27477658-5	2016	Through continuous study of the structure-CaSR-activity relation of a large number of gamma-glutamyl peptides, we have determined that the structural requirements for intense CaSR activity of gamma-glutamyl peptides are as follows: existence of an N-terminal gamma-L-glutamyl residue; existence of a moderately sized, aliphatic, neutral substituent at the second residue in an L-configuration; and existence of a C-terminal carboxylic acid, preferably with the existence of glycine as the third constituent.	Glycine	474-481	calcium sensing receptor	Homo sapiens	175-179
26766775-5	2016	We identified linear IgE-binding epitopes of the major storage protein Gly m 6 by screening individual soy-sensitive patient sera.	Glycine	71-74	immunoglobulin heavy constant epsilon	Homo sapiens	21-24
26821380-8	2016	Based on these findings, we observed that high levels of exogenous glycine, or 5-aminolevulinic acid (5-Ala) a metabolite downstream of Hem25 in heme biosynthetic pathway, were able to restore heme levels to normal in yeast cells lacking Hem25 function.	Glycine	67-74	Hem25p	Saccharomyces cerevisiae S288C	136-141
26821380-8	2016	Based on these findings, we observed that high levels of exogenous glycine, or 5-aminolevulinic acid (5-Ala) a metabolite downstream of Hem25 in heme biosynthetic pathway, were able to restore heme levels to normal in yeast cells lacking Hem25 function.	Glycine	67-74	Hem25p	Saccharomyces cerevisiae S288C	238-243
26864036-3	2016	We propose that mouse UCP2 has two glycine-rich motifs, motif 1: EGIRGLWKG (170-178) and a known Walker A-like motif 2: EGPRAFYKG (264-272).	Glycine	35-42	uncoupling protein 2 (mitochondrial, proton carrier)	Mus musculus	22-26
27048272-2	2016	Two high-affinity and substrate selective transporters, glycine transporter-1 and glycine transporter-2 (GlyT-1 and GlyT-2), regulate extracellular glycine concentrations within the CNS and as such, play critical roles in maintaining a balance between inhibitory and excitatory neurotransmission.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	105-111
26670557-2	2015	Here we show that treatment of mice with glycine-beta-muricholic acid (Gly-MCA) inhibits FXR signalling exclusively in intestine, and improves metabolic parameters in mouse models of obesity.	Glycine	41-48	nuclear receptor subfamily 1, group H, member 4	Mus musculus	89-92
26818177-4	2016	There are five known eRF3a/GSPT1 alleles in the human population, encoding 7, 9, 10, 11 and 12 glycines.	Glycine	95-103	G1 to S phase transition 1	Homo sapiens	21-26
26818177-4	2016	There are five known eRF3a/GSPT1 alleles in the human population, encoding 7, 9, 10, 11 and 12 glycines.	Glycine	95-103	G1 to S phase transition 1	Homo sapiens	27-32
26818177-7	2016	We found that the N-terminal glycine repeat of eRF3a influences eRF3a-PABP interaction and that eRF3a 12-GGC allele has a decreased binding affinity for PABP.	Glycine	29-36	G1 to S phase transition 1	Homo sapiens	47-52
26818177-7	2016	We found that the N-terminal glycine repeat of eRF3a influences eRF3a-PABP interaction and that eRF3a 12-GGC allele has a decreased binding affinity for PABP.	Glycine	29-36	G1 to S phase transition 1	Homo sapiens	64-69
26818177-7	2016	We found that the N-terminal glycine repeat of eRF3a influences eRF3a-PABP interaction and that eRF3a 12-GGC allele has a decreased binding affinity for PABP.	Glycine	29-36	G1 to S phase transition 1	Homo sapiens	64-69
26511319-1	2015	5-Aminolevulinate synthase (ALAS) catalyzes the first step in mammalian heme biosynthesis, the pyridoxal 5"-phosphate (PLP)-dependent and reversible reaction between glycine and succinyl-CoA to generate CoA, CO2, and 5-aminolevulinate (ALA).	Glycine	166-173	5'-aminolevulinate synthase 1	Homo sapiens	0-26
26511319-1	2015	5-Aminolevulinate synthase (ALAS) catalyzes the first step in mammalian heme biosynthesis, the pyridoxal 5"-phosphate (PLP)-dependent and reversible reaction between glycine and succinyl-CoA to generate CoA, CO2, and 5-aminolevulinate (ALA).	Glycine	166-173	5'-aminolevulinate synthase 1	Homo sapiens	28-32
26818177-0	2016	Studies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility.	Glycine	80-86	G1 to S phase transition 1	Homo sapiens	63-68
26818177-3	2016	In humans, eRF3a/GSPT1 gene contains a stable GGC repeat encoding a repeat of glycine residues in eRF3a N-terminus.	Glycine	78-85	G1 to S phase transition 1	Homo sapiens	11-16
26818177-3	2016	In humans, eRF3a/GSPT1 gene contains a stable GGC repeat encoding a repeat of glycine residues in eRF3a N-terminus.	Glycine	78-85	G1 to S phase transition 1	Homo sapiens	17-22
26818177-3	2016	In humans, eRF3a/GSPT1 gene contains a stable GGC repeat encoding a repeat of glycine residues in eRF3a N-terminus.	Glycine	78-85	G1 to S phase transition 1	Homo sapiens	98-103
26716989-9	2015	In particular, the abundance of glycine, citrulline, arachidonic acid, and saturated fatty acids in TNF-alpha-stimulated FLS was restored to the control level after treatment with curcumin, suggesting that the effect of curcumin on preventing joint inflammation may be elucidated with the levels of these metabolites.	Glycine	32-39	tumor necrosis factor	Homo sapiens	100-109
26675719-4	2015	Here we show that substitution of the conserved glycine 388 residue to a charged arginine residue alters the transmembrane spanning segment and exposes a membrane-proximal cytoplasmic signal transducer and activator of transcription 3 (STAT3) binding site Y(390)-(P)XXQ(393).	Glycine	48-55	signal transducer and activator of transcription 3	Mus musculus	184-234
26675719-4	2015	Here we show that substitution of the conserved glycine 388 residue to a charged arginine residue alters the transmembrane spanning segment and exposes a membrane-proximal cytoplasmic signal transducer and activator of transcription 3 (STAT3) binding site Y(390)-(P)XXQ(393).	Glycine	48-55	signal transducer and activator of transcription 3	Mus musculus	236-241
26670557-3	2015	Gly-MCA is a selective high-affinity FXR inhibitor that can be administered orally and prevents, or reverses, high-fat diet-induced and genetic obesity, insulin resistance and hepatic steatosis in mice.	Glycine	0-3	nuclear receptor subfamily 1, group H, member 4	Mus musculus	37-40
26670557-4	2015	The high-affinity FXR agonist GW4064 blocks Gly-MCA action in the gut, and intestine-specific Fxr-null mice are unresponsive to the beneficial effects of Gly-MCA.	Glycine	44-47	nuclear receptor subfamily 1, group H, member 4	Mus musculus	18-21
26200505-12	2015	We conclude that BDNF, acting on TrkB-T1 receptors, inhibits glycine uptake in astrocytes by promoting GlyT internalization through a Rho-GTPase activity dependent mechanism.	Glycine	61-68	neurotrophic receptor tyrosine kinase 2	Rattus norvegicus	33-37
26378233-5	2015	We demonstrated that the glycine-rich N-terminal region of SPS is crucial for the SelA-tRNA(Sec)-SPS interaction and selenoprotein biosynthesis, as revealed by functional complementation experiments.	Glycine	25-32	selenophosphate synthetase 1	Homo sapiens	59-62
26378233-5	2015	We demonstrated that the glycine-rich N-terminal region of SPS is crucial for the SelA-tRNA(Sec)-SPS interaction and selenoprotein biosynthesis, as revealed by functional complementation experiments.	Glycine	25-32	mitochondrially encoded tRNA glycine	Homo sapiens	87-96
26378233-5	2015	We demonstrated that the glycine-rich N-terminal region of SPS is crucial for the SelA-tRNA(Sec)-SPS interaction and selenoprotein biosynthesis, as revealed by functional complementation experiments.	Glycine	25-32	selenophosphate synthetase 1	Homo sapiens	97-100
26631477-5	2015	Using subunit-selective allosteric modulators of NMDA receptors (TCN-201, ifenprodil, CIQ, and DQP-1105), we provide evidence that receptors containing the GluN2B and GluN2D subunits mediate responses to exogenously applied NMDA and glycine, as well as synaptic NMDA receptor activation in the STN of rat brain slices.	Glycine	233-240	glutamate ionotropic receptor NMDA type subunit 2D	Rattus norvegicus	167-173
26482881-6	2015	Thus, a substantial fraction of human NSCLCs activates an NRF2-dependent transcriptional program that regulates serine and glycine metabolism and is linked to clinical aggressiveness.	Glycine	123-130	NFE2 like bZIP transcription factor 2	Homo sapiens	58-62
26482881-4	2015	We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production.	Glycine	61-68	NFE2 like bZIP transcription factor 2	Homo sapiens	14-18
26168863-5	2015	Transport function of PEPT2 was studied using glycylsarcosine (Gly-Sar) as a substrate.	Glycine	63-66	solute carrier family 15 member 2	Homo sapiens	22-27
26585387-7	2015	Relief of hypersuccinylation by overexpressing the desuccinylase SIRT5 or supplementing glycine rescued mitochondrial dysfunctions, reversed BCL-2 accumulation, and slowed the oncogenic growth of hypersuccinylated IDH1(R132C)-harboring HT1080 cells.	Glycine	88-95	BCL2 apoptosis regulator	Homo sapiens	141-146
27066571-6	2015	CONCLUSIONS: This novel L1CAM mutation was located in the protein"s sixth immunoglobin domain and involved glycine-587, a key residue in the structure of L1CAM because of its interactions with lysine-606, which indicates that any mutation at this site would likely affect the secondary structure and function of the protein.	Glycine	107-114	L1 cell adhesion molecule	Homo sapiens	24-29
27066571-6	2015	CONCLUSIONS: This novel L1CAM mutation was located in the protein"s sixth immunoglobin domain and involved glycine-587, a key residue in the structure of L1CAM because of its interactions with lysine-606, which indicates that any mutation at this site would likely affect the secondary structure and function of the protein.	Glycine	107-114	L1 cell adhesion molecule	Homo sapiens	154-159
26239085-8	2015	RESULTS: The parent glycine conjugate and two modified conjugates all showed selective tumor uptake in Mec-1 xenografts.	Glycine	20-27	ATR serine/threonine kinase	Homo sapiens	103-108
26446788-2	2015	T. cruzi autophagin-2 (TcAtg4.2) carries the majority of proteolytic activity and is responsible for processing Atg8 proteins near the carboxyl terminus, exposing a conserved glycine.	Glycine	175-182	GABA type A receptor associated protein like 1	Homo sapiens	112-116
26446788-6	2015	In contrast, both human and trypanosome Atg4 orthologues exhibited exclusive preference for aromatic amino acid residues in the P2 position, and for Gly in the P1 position, which is absolutely conserved in the natural Atg8 substrates.	Glycine	149-152	GABA type A receptor associated protein like 1	Homo sapiens	218-222
26160850-7	2015	Our results reveal an essential role for the Cys-Gly-Cys triad in Nox2 in binding p67(phox), seconded by an additional binding region, comprising residues C terminal to Cys-Gly-Cys.	Glycine	49-52	CD33 molecule	Homo sapiens	82-85
26254576-10	2015	CONCLUSIONS/INTERPRETATION: A mechanism involving more efficient elimination of excess acyl groups derived from BCAA and aromatic AA metabolism via glycine conjugation in the liver, rather than increased BCAA disposal through oxidation and turnover, may mediate interactions between exercise, BCAA metabolism and IS.	Glycine	148-155	AT-rich interaction domain 4B	Homo sapiens	112-116
26362185-4	2015	The results showed that CRT binds strongly to a G1M9-ligand in the order -Gly-Glu-(t)Bu &gt; -Gly-NH2 &gt; -OH, which is the same as that of the reglucosylation of Man9GlcNAc2 (M9)-derivatives by the folding sensor enzyme UGGT (UDP-glucose: glycoprotein glucosyltransferase).	Glycine	74-77	calreticulin	Homo sapiens	24-27
26362185-4	2015	The results showed that CRT binds strongly to a G1M9-ligand in the order -Gly-Glu-(t)Bu &gt; -Gly-NH2 &gt; -OH, which is the same as that of the reglucosylation of Man9GlcNAc2 (M9)-derivatives by the folding sensor enzyme UGGT (UDP-glucose: glycoprotein glucosyltransferase).	Glycine	94-97	calreticulin	Homo sapiens	24-27
26139616-7	2015	The most economical and optimal refolding condition for human preproinsulin was 1.5 g/l protein, 10 mM glycine buffer containing 0.6 M urea, pH 10.6, and 0.3 mM beta-mercaptoethanol at 15 C for 16 h. The maximum refolding yield was 74.8% at 15 C with 1.5 g/l protein.	Glycine	103-110	insulin	Homo sapiens	62-75
26664375-5	2015	The study showed that the p-SO2Me-phenyl fragment of 5e inserted inside secondary COX-2 binding site (Arg(513), Phe(518), Gly(519), and His(90)).	Glycine	122-125	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	82-87
25339225-3	2015	We found that the apparent affinity of glycine to GluN1 (K gly ~ 0.6 muM) is much higher than NMDA or glutamate to GluN2 (K NMDA ~ 36 muM, K glu ~ 4.8 muM).	Glycine	39-46	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	50-55
26082520-2	2015	The adaptor protein CD2BP2, originally identified as a binding partner of the adhesion molecule CD2, is a pre-spliceosomal assembly factor that utilizes its glycine-tyrosine-phenylalanine (GYF) domain to co-localize with spliceosomal proteins.	Glycine	157-164	CD2 cytoplasmic tail binding protein 2	Mus musculus	20-26
26252573-4	2015	A single base mutation from cytosine to guanine at site 1582 was identified in exon 11 of CACNA1S in one FHPP pedigree, resulting in an arginine to glycine (R528G) substitution.	Glycine	148-155	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	90-97
26238930-1	2015	Previous studies have demonstrated that the alpha5beta1 integrin-mediated interaction with fibronectin (FN) occurs through the Arg-Gly-Asp (RGD) cell-binding sequence in repeat III10.	Glycine	131-134	fibronectin 1	Homo sapiens	91-102
26374839-2	2015	FMRP uses an arginine-glycine-rich (RGG) motif for specific interactions with guanine (G)-quadruplexes, mRNA elements implicated in the disease-associated regulation of specific mRNAs.	Glycine	22-29	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
25932687-1	2015	Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the modulation of glycinergic inhibition in pain signaling.	Glycine	79-86	solute carrier family 6 member 9	Homo sapiens	0-21
25932687-1	2015	Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the modulation of glycinergic inhibition in pain signaling.	Glycine	79-86	solute carrier family 6 member 9	Homo sapiens	23-28
25932687-3	2015	We have shown previously that the lidocaine metabolite N-ethylglycine (EG) reduces GlyT1-dependent glycine uptake by functioning as an artificial substrate for this transporter.	Glycine	62-69	solute carrier family 6 member 9	Homo sapiens	83-88
25719321-11	2015	CONCLUSIONS: While the influence observed for glycine may be due to fibrinogen precipitation, the mechanism of mannitol appears to be more complex as platelet function as well as fibrin-based clot formation are influenced.	Glycine	46-53	fibrinogen beta chain	Homo sapiens	68-78
25339225-3	2015	We found that the apparent affinity of glycine to GluN1 (K gly ~ 0.6 muM) is much higher than NMDA or glutamate to GluN2 (K NMDA ~ 36 muM, K glu ~ 4.8 muM).	Glycine	39-42	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	50-55
25339225-4	2015	The binding rate constant (derived from the linear regression of the apparent macroscopic binding rates) of glycine to GluN1 (~9.8 x 10(6) M(-1) s(-1)), however, is only slightly faster than NMDA to GluN2 (~4.1 x 10(6) M(-1) s(-1)).	Glycine	108-115	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	119-124
25339225-5	2015	Accordingly, the apparent unbinding rates of glycine from activated GluN1 (time constant ~2 s) are much slower than NMDA from activated GluN2 (time constant ~70 ms).	Glycine	45-52	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	68-73
25339225-10	2015	Moreover, specific mutations involving A7 in GluN1 but not in GluN2 result in channels showing markedly enhanced affinity to both glycine and NMDA and readily activated by only NMDA, as if the channel is already partially activated.	Glycine	130-137	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	45-50
26200251-6	2015	Analysis of axon growth from cultured neurons expressing deletion mutants of the CaSR cytoplasmic tail revealed that the region between alanine 877 and glycine 907 is required for promoting axon growth that is distinct from the high-affinity filamin-A binding site that has previously been implicated in ERK1/ERK2 activation.	Glycine	152-159	calcium sensing receptor	Homo sapiens	81-85
26317500-7	2015	Avr3b contains a putative Glycine-Proline (GP) motif; which is known to confer cyclophilin-binding in other protein substrates.	Glycine	26-33	peptidyl-prolyl cis-trans isomerase 1	Glycine max	79-90
26086092-3	2015	It was found that polyamines, especially spermidine, can permeate NMDA channels expressed from GluN1/GluN2A or GluN1/GluN2B activated by glycine and glutamate.	Glycine	137-144	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	95-100
26086092-3	2015	It was found that polyamines, especially spermidine, can permeate NMDA channels expressed from GluN1/GluN2A or GluN1/GluN2B activated by glycine and glutamate.	Glycine	137-144	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	111-116
26300626-0	2015	Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-kappaB, an anti-inflammatory target.	Glycine	14-21	nuclear factor kappa B subunit 1	Homo sapiens	97-118
26300626-3	2015	Glycine-bearing celecoxib derivatives were prepared and evaluated as a colon-specific mutual prodrug acting on nuclear factor-kappaB (NFkappaB), an anticolitic target.	Glycine	0-7	nuclear factor kappa B subunit 1	Homo sapiens	111-132
26300626-3	2015	Glycine-bearing celecoxib derivatives were prepared and evaluated as a colon-specific mutual prodrug acting on nuclear factor-kappaB (NFkappaB), an anticolitic target.	Glycine	0-7	nuclear factor kappa B subunit 1	Homo sapiens	134-142
25998124-10	2015	The results indicate that both glycines are important for RyR1 channel function by providing flexibility and minimizing amino acid clashes.	Glycine	31-39	ryanodine receptor 1	Homo sapiens	58-62
25891130-2	2015	ADAM15 is unique among the ADAMs in having an Arg-Gly-Asp motif in its disintegrin domain.	Glycine	50-53	ADAM metallopeptidase domain 15	Homo sapiens	0-6
25870943-11	2015	In conclusion, the speculated regulatory role of ORF1 X-domain in HEV replication cycle critically depends on the "Asn, Asn, His, Gly, Gly, Gly" segment/secondary structure.	Glycine	130-133	polyprotein	Orthohepevirus A	49-53
25870943-11	2015	In conclusion, the speculated regulatory role of ORF1 X-domain in HEV replication cycle critically depends on the "Asn, Asn, His, Gly, Gly, Gly" segment/secondary structure.	Glycine	135-138	polyprotein	Orthohepevirus A	49-53
25870943-11	2015	In conclusion, the speculated regulatory role of ORF1 X-domain in HEV replication cycle critically depends on the "Asn, Asn, His, Gly, Gly, Gly" segment/secondary structure.	Glycine	135-138	polyprotein	Orthohepevirus A	49-53
26132652-2	2015	An all-atom three-dimensional molecular model was constructed on the basis of a crystal structure from the Protein Data Bank (ID: 1QIB), and the oligopeptide Ace-Gln-Gly~Ile-Ala-Gly-Nme was considered as the substrate.	Glycine	166-169	angiotensin I converting enzyme	Homo sapiens	158-161
26132652-2	2015	An all-atom three-dimensional molecular model was constructed on the basis of a crystal structure from the Protein Data Bank (ID: 1QIB), and the oligopeptide Ace-Gln-Gly~Ile-Ala-Gly-Nme was considered as the substrate.	Glycine	178-181	angiotensin I converting enzyme	Homo sapiens	158-161
26010440-1	2015	The aim of this study was to elucidate the inhibition mechanism of 18beta-glycyrrhetic acid (GLY) on cytochrome P450 (CYP) activity and in vivo pharmacokinetic consequences of single GLY dose in rats.	Glycine	93-96	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	101-116
26010440-1	2015	The aim of this study was to elucidate the inhibition mechanism of 18beta-glycyrrhetic acid (GLY) on cytochrome P450 (CYP) activity and in vivo pharmacokinetic consequences of single GLY dose in rats.	Glycine	93-96	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	118-121
26010440-4	2015	In the in vitro CYP inhibition study, CYP3A was involved in the metabolism of GLY.	Glycine	78-81	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	16-19
26010440-4	2015	In the in vitro CYP inhibition study, CYP3A was involved in the metabolism of GLY.	Glycine	78-81	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	38-43
26010440-5	2015	Moreover, GLY inhibited CYP3A activity with an IC50 of 20.1 +- 10.7 muM via a mixed inhibition mechanism.	Glycine	10-13	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	24-29
26010440-7	2015	These results indicate that GLY can inhibit the in vitro CYP3A-mediated drug metabolism in RLM via a mixed inhibition mechanism.	Glycine	28-31	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	57-62
26010440-8	2015	However, the impact of single oral GLY dose on the pharmacokinetics of BUS in rats was limited, showing that GLY could function as merely a weak inhibitor for CYP3A-mediated drug metabolism in vivo.	Glycine	109-112	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	159-164
26032551-7	2015	Studies demonstrate that bladder cancer cells in which AGL expression is lost are more metabolically active than cells with intact AGL expression, and these cells are more sensitive to inhibition of both glycolysis and glycine synthesis--two targetable pathways.	Glycine	219-226	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	55-58
26138272-4	2015	Substituting leucine by glycine within the MetRS-binding pocket (MetRS(LtoG)) enables incorporation of the non-canonical amino acid azidonorleucine (ANL) instead of methionine during translation.	Glycine	24-31	Methionyl-tRNA synthetase	Drosophila melanogaster	43-48
26138272-4	2015	Substituting leucine by glycine within the MetRS-binding pocket (MetRS(LtoG)) enables incorporation of the non-canonical amino acid azidonorleucine (ANL) instead of methionine during translation.	Glycine	24-31	Methionyl-tRNA synthetase	Drosophila melanogaster	65-70
25858481-0	2015	Severe osteogenesis imperfecta caused by double glycine substitutions near the amino-terminal triple helical region in COL1A2.	Glycine	48-55	collagen type I alpha 2 chain	Homo sapiens	119-125
25858481-2	2015	We report on a unique case of severe OI, a long term survivor of lethal type II OI, rather than progressively deforming type III, due to double substitutions of glycine residues in COL1A2 (p.Gly208Glu and p.Gly235Asp), located on the same allele.	Glycine	161-168	collagen type I alpha 2 chain	Homo sapiens	181-187
25858481-3	2015	To the best of our knowledge, this is the first example of a patient with double COL1A2 glycine substitution mutations on the same allele.	Glycine	88-95	collagen type I alpha 2 chain	Homo sapiens	81-87
25858481-4	2015	We show for the first time that double COL1A2 glycine substitution mutations located near the amino-terminal triple helical region, which individually are likely to result in mild OI, cause severe OI in combination.	Glycine	46-53	collagen type I alpha 2 chain	Homo sapiens	39-45
25900302-2	2015	SEDC is usually caused by substitution of glycine residue with another amino acid in the triple helical domains of alpha 1 chains, which consist of type II collagen (COL2A1).	Glycine	42-49	collagen type II alpha 1 chain	Homo sapiens	0-4
25900302-2	2015	SEDC is usually caused by substitution of glycine residue with another amino acid in the triple helical domains of alpha 1 chains, which consist of type II collagen (COL2A1).	Glycine	42-49	collagen type II alpha 1 chain	Homo sapiens	166-172
26147390-3	2015	Here, we identify a conserved GGxxG motif in the CD4 transmembrane domain that is related to the previously described GxxxG motifs of other proteins and predicted to form a flat glycine patch in a transmembrane helix.	Glycine	178-185	CD4 molecule	Homo sapiens	49-52
26240838-5	2015	Specifically, compared with undecorated gels, those functionalized with Arg-Gly-Asp-Ser (RGDS) peptides increase the proliferative activity of NSCs; promote their directional migration; induce differentiation, with increased expression of microtubule-associated protein-2, and a low expression of glial fibrillary acidic protein; and lead to the formation of larger neurospheres.	Glycine	76-79	microtubule-associated protein 2	Mus musculus	239-271
26046984-11	2015	Conversely, overexpression of the ubiquitin ligase Nedd4-2 decreased Igly-gly.	Glycine	70-73	NEDD4 like E3 ubiquitin protein ligase S homeolog	Xenopus laevis	51-58
25845371-8	2015	A novel heterozygous mutation in COL5A1 was detected, resulting in an essential glycine substitution at the C-terminal end of the triple helix domain (NM_000093.4:c.4610G&gt;T; p.Gly1537Val).	Glycine	80-87	collagen type V alpha 1 chain	Homo sapiens	33-39
26030151-5	2015	Our study extends the mutation spectrum of SEDC and confirms genotype-phenotype relationship between mutations at glycine in the triple helix of the alpha-1(II) chains of the COL2A1 and clinical findings of SEDC, which may be helpful in the genetic counseling of patients with SEDC.	Glycine	114-121	collagen type II alpha 1 chain	Homo sapiens	43-47
25988540-10	2015	Glycine increased the mRNA expression of eNOS and decreased the expression of COX-2 and TNF-alpha.	Glycine	0-7	tumor necrosis factor	Rattus norvegicus	88-97
25964432-5	2015	We examined currents recorded from cell-attached patches containing one GluN1/GluN2A receptor in the presence of several glycine-site agonists and used kinetic modeling of these data to develop reaction schemes that include explicit glycine-binding steps.	Glycine	233-240	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	72-77
25964432-7	2015	These results complete the basic steps of an NMDA receptor reaction scheme for the GluN1/GluN2A isoform and prompt a reevaluation of how glycine controls NMDA receptor activation.	Glycine	137-144	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	83-88
25964432-7	2015	These results complete the basic steps of an NMDA receptor reaction scheme for the GluN1/GluN2A isoform and prompt a reevaluation of how glycine controls NMDA receptor activation.	Glycine	137-144	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	89-95
25041275-0	2015	Insulin glargine metabolite 21(A) -Gly-human insulin (M1) is the principal component circulating in the plasma of young children with type 1 diabetes: results from the PRESCHOOL study.	Glycine	35-38	insulin	Homo sapiens	0-7
25041275-0	2015	Insulin glargine metabolite 21(A) -Gly-human insulin (M1) is the principal component circulating in the plasma of young children with type 1 diabetes: results from the PRESCHOOL study.	Glycine	35-38	insulin	Homo sapiens	45-52
25041275-1	2015	BACKGROUND AND AIMS: Insulin glargine metabolite 21(A) -Gly-human insulin (M1) is the principal component circulating in plasma of adults with type 1 diabetes.	Glycine	56-59	insulin	Homo sapiens	21-28
25041275-1	2015	BACKGROUND AND AIMS: Insulin glargine metabolite 21(A) -Gly-human insulin (M1) is the principal component circulating in plasma of adults with type 1 diabetes.	Glycine	56-59	insulin	Homo sapiens	66-73
26030151-5	2015	Our study extends the mutation spectrum of SEDC and confirms genotype-phenotype relationship between mutations at glycine in the triple helix of the alpha-1(II) chains of the COL2A1 and clinical findings of SEDC, which may be helpful in the genetic counseling of patients with SEDC.	Glycine	114-121	collagen type II alpha 1 chain	Homo sapiens	175-181
26030151-5	2015	Our study extends the mutation spectrum of SEDC and confirms genotype-phenotype relationship between mutations at glycine in the triple helix of the alpha-1(II) chains of the COL2A1 and clinical findings of SEDC, which may be helpful in the genetic counseling of patients with SEDC.	Glycine	114-121	collagen type II alpha 1 chain	Homo sapiens	207-211
26030151-5	2015	Our study extends the mutation spectrum of SEDC and confirms genotype-phenotype relationship between mutations at glycine in the triple helix of the alpha-1(II) chains of the COL2A1 and clinical findings of SEDC, which may be helpful in the genetic counseling of patients with SEDC.	Glycine	114-121	collagen type II alpha 1 chain	Homo sapiens	207-211
25561692-6	2015	The SMN complex is proposed to form a dimer driven by formation of a glycine zipper involving alpha helix formed by amino acid residues 263-294.	Glycine	69-76	small nuclear ribonucleoprotein polypeptide N	Homo sapiens	4-7
25616961-6	2015	The interacting region in each of these proteins was their glycine-rich domain, the domain most frequently mutated in hnRNP-related proteins that cause ALS.	Glycine	59-66	superoxide dismutase 1	Homo sapiens	152-155
25418841-0	2015	Glycine bidirectionally regulates ischemic tolerance via different mechanisms including NR2A-dependent CREB phosphorylation.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	88-92
25418841-7	2015	Importantly, L-Gly-induced IT was achieved by NR2A-dependent cAMP-response element binding protein phosphorylation.	Glycine	13-18	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	46-50
25637053-7	2015	Accordingly, the shedding of the transferrin receptor-2 variant G679A, mutated in the Arginine-Glycine-Aspartic acid motif and unable to bind diferric transferrin, is not modulated by the ligand.	Glycine	95-102	transferrin	Homo sapiens	33-44
26484019-3	2015	The rs2276415 (G&gt;A) single-nucleotide polymorphism in the human AQP11 gene results in glycine to serine substitution in a functionally important domain.	Glycine	89-96	aquaporin 11	Homo sapiens	67-72
25577037-0	2015	Dual receptor-targeting 99mTc-labeled Arg-Gly-Asp-conjugated Alpha-Melanocyte stimulating hormone hybrid peptides for human melanoma imaging.	Glycine	42-45	proopiomelanocortin	Homo sapiens	61-97
25736695-1	2015	Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism.	Glycine	41-48	glycine decarboxylase	Mus musculus	0-21
25736695-1	2015	Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism.	Glycine	41-48	glycine decarboxylase	Mus musculus	23-27
25736695-1	2015	Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism.	Glycine	82-89	glycine decarboxylase	Mus musculus	0-21
25736695-1	2015	Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism.	Glycine	82-89	glycine decarboxylase	Mus musculus	23-27
25736695-4	2015	We show that reduced expression of Gldc in mice suppresses glycine cleavage system activity and causes two distinct disease phenotypes.	Glycine	59-66	glycine decarboxylase	Mus musculus	35-39
25736695-6	2015	In addition to elevated glycine, Gldc disruption also results in abnormal tissue folate profiles, with depletion of one-carbon-carrying folates, as well as growth retardation and reduced cellular proliferation.	Glycine	24-31	glycine decarboxylase	Mus musculus	33-37
25681283-6	2015	A further prolonged analog, f-Nle-Leu-Phe-Nle-Tyr-Lys-(Asn-Gly)5-myc, designed to decrease the possible steric hindrance between FPR1 and the bound anti-myc antibody, has little affinity for the receptor, precluding a direct assessment of this issue.	Glycine	59-62	formyl peptide receptor 1	Homo sapiens	129-133
25416280-2	2015	FMRP is a selective RNA binding protein owing to two central K-homology domains and a C-terminal arginine-glycine-glycine (RGG) box.	Glycine	106-113	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
25416280-2	2015	FMRP is a selective RNA binding protein owing to two central K-homology domains and a C-terminal arginine-glycine-glycine (RGG) box.	Glycine	114-121	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
25874008-2	2015	The anti-gastrin antiserum was obtained by immunizing rabbits using a novel immunogen vaccine, which was composed of the common amino-terminal portion of human carboxy-amidated gastrin-17 (G17) and glycine-extended gastrin-17 (gly-G17) and the common carboxy-terminal portion of progastrin (in a 50:50 mixture) all covalently linked to tetanus toxoid (TT) by specific peptide spacers.	Glycine	198-205	gastrin	Oryctolagus cuniculus	9-16
25874008-2	2015	The anti-gastrin antiserum was obtained by immunizing rabbits using a novel immunogen vaccine, which was composed of the common amino-terminal portion of human carboxy-amidated gastrin-17 (G17) and glycine-extended gastrin-17 (gly-G17) and the common carboxy-terminal portion of progastrin (in a 50:50 mixture) all covalently linked to tetanus toxoid (TT) by specific peptide spacers.	Glycine	198-201	gastrin	Oryctolagus cuniculus	9-16
25360832-0	2015	Green tea and glycine aid in the recovery of tendinitis of the Achilles tendon of rats.	Glycine	14-21	activation-induced cytidine deaminase	Rattus norvegicus	22-25
25602614-8	2015	Our findings show that all the descriptors add up to favor the primary deamidation site over the secondary one in mammalian TPI: Asn71 deamidates faster because it is more solvent accessible, the adjacent glycine NH backbone acidity is enhanced, and the Asn side chain has a preferential near attack conformation.	Glycine	205-212	triosephosphate isomerase 1	Homo sapiens	124-127
25228381-9	2015	Compared with rats in the sepsis and the scrambled shRNA groups, rats in the NLRP3 shRNA group exhibited significantly decreased serum levels of glycine and taurine conjugated-bile acids, with rehabilitated expression of hepatocyte transporters, suppressed hepatic cytokine levels, decreased hepatic neutrophils infiltration and attenuated macrophages pyroptosis.	Glycine	145-152	NLR family, pyrin domain containing 3	Rattus norvegicus	77-82
25360832-15	2015	The results suggest that GT + a glycine diet has beneficial effects that aid in the recovery process of the tendon after tendinitis.	Glycine	32-39	activation-induced cytidine deaminase	Rattus norvegicus	73-76
25447237-3	2015	It has been shown in cell culture that the nuclear import of FUS is mediated by transportin, which binds the PY-NLS and the last arginine/glycine/glycine-rich (RGG) domain of FUS.	Glycine	138-145	FUS RNA binding protein	Homo sapiens	61-64
25521062-6	2015	Native NMU was found to be rapidly cleaved at the C-terminus between Arg(24) and Asn(25) , followed by cleavage between Arg(16) and Gly(17) .	Glycine	132-135	neuromedin U	Homo sapiens	7-10
25523083-4	2015	The autoproteolytic cleavage of Anabaena LexA occurs at pH 8.5 and above, stimulated by the addition of Ca(2+) and in the temperature range of 30-57 C. Mutational analysis of Anabaena LexA protein indicated that the cleavage occurred at the peptide bond between Ala-84 and Gly-85, and optimal cleavage required the presence of Ser-118 and Lys-159, as also observed for LexA protein of Escherichia coli.	Glycine	273-276	DNA repair system	Escherichia coli	41-45
25523083-4	2015	The autoproteolytic cleavage of Anabaena LexA occurs at pH 8.5 and above, stimulated by the addition of Ca(2+) and in the temperature range of 30-57 C. Mutational analysis of Anabaena LexA protein indicated that the cleavage occurred at the peptide bond between Ala-84 and Gly-85, and optimal cleavage required the presence of Ser-118 and Lys-159, as also observed for LexA protein of Escherichia coli.	Glycine	273-276	DNA repair system	Escherichia coli	184-188
25523083-4	2015	The autoproteolytic cleavage of Anabaena LexA occurs at pH 8.5 and above, stimulated by the addition of Ca(2+) and in the temperature range of 30-57 C. Mutational analysis of Anabaena LexA protein indicated that the cleavage occurred at the peptide bond between Ala-84 and Gly-85, and optimal cleavage required the presence of Ser-118 and Lys-159, as also observed for LexA protein of Escherichia coli.	Glycine	273-276	DNA repair system	Escherichia coli	184-188
25620423-5	2015	MD simulations revealed that the L755P mutation caused structural changes in the regions of helix alphaC, the glycine-rich loop, and the activation loop, thereby leading to the loss of interactions between the solubilizing group of lapatinib and HER2.	Glycine	110-117	erb-b2 receptor tyrosine kinase 2	Homo sapiens	246-250
25447237-3	2015	It has been shown in cell culture that the nuclear import of FUS is mediated by transportin, which binds the PY-NLS and the last arginine/glycine/glycine-rich (RGG) domain of FUS.	Glycine	138-145	FUS RNA binding protein	Homo sapiens	175-178
25447237-3	2015	It has been shown in cell culture that the nuclear import of FUS is mediated by transportin, which binds the PY-NLS and the last arginine/glycine/glycine-rich (RGG) domain of FUS.	Glycine	146-153	FUS RNA binding protein	Homo sapiens	61-64
25447237-3	2015	It has been shown in cell culture that the nuclear import of FUS is mediated by transportin, which binds the PY-NLS and the last arginine/glycine/glycine-rich (RGG) domain of FUS.	Glycine	146-153	FUS RNA binding protein	Homo sapiens	175-178
25544544-4	2015	We show herein that the ligand binding domains (LBD) of the GluN1 and GluN2A subunits of the NMDAR heterodimerize only when both coagonists, Glu and Gly/d-Ser, bind to their respective sites on GluN2 and GluN1.	Glycine	149-152	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	204-209
25544544-4	2015	We show herein that the ligand binding domains (LBD) of the GluN1 and GluN2A subunits of the NMDAR heterodimerize only when both coagonists, Glu and Gly/d-Ser, bind to their respective sites on GluN2 and GluN1.	Glycine	149-152	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	60-65
25544544-4	2015	We show herein that the ligand binding domains (LBD) of the GluN1 and GluN2A subunits of the NMDAR heterodimerize only when both coagonists, Glu and Gly/d-Ser, bind to their respective sites on GluN2 and GluN1.	Glycine	149-152	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	70-76
25544544-6	2015	Also, in a heteromer formed by the LBDs, GluN2A is more sensitized to bind Glu, while the affinity of Gly for GluN1 remains unchanged.	Glycine	102-105	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	110-115
25582325-1	2015	BACKGROUND: We have previously shown that serum levels of glyceraldehyde-derived advanced glycation end products (Gly-AGEs) are elevated under oxidative stress and/or diabetic conditions and associated with insulin resistance, endothelial dysfunction and vascular inflammation in humans.	Glycine	114-117	insulin	Homo sapiens	207-214
25550512-6	2015	During postnatal development, the replacement of GluN2B- by GluN2A-containing NMDARs at SC-CA1 synapses parallels a change in the identity of the coagonist from glycine to D-serine.	Glycine	161-168	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	60-66
25205112-4	2015	Mutant glycine 305 is a highly conserved amino acid present in the eighth transmembrane segment of all metazoan orthologues of NHE1, the Na(+)/H(+) exchanger 1, encoded by SLC9A1.	Glycine	7-14	solute carrier family 9 (sodium/hydrogen exchanger), member 1	Mus musculus	127-131
25205112-4	2015	Mutant glycine 305 is a highly conserved amino acid present in the eighth transmembrane segment of all metazoan orthologues of NHE1, the Na(+)/H(+) exchanger 1, encoded by SLC9A1.	Glycine	7-14	solute carrier family 9 (sodium/hydrogen exchanger), member 1	Mus musculus	137-159
25205112-4	2015	Mutant glycine 305 is a highly conserved amino acid present in the eighth transmembrane segment of all metazoan orthologues of NHE1, the Na(+)/H(+) exchanger 1, encoded by SLC9A1.	Glycine	7-14	solute carrier family 9 (sodium/hydrogen exchanger), member 1	Mus musculus	172-178
25821801-6	2015	Alanine and glycine explained 10% of insulin resistance variability.	Glycine	12-19	insulin	Homo sapiens	37-44
26558949-1	2015	Protein N-myristoylation is a ubiquitous cotranslational and posttranslational modification catalyzed by myristoyl CoA:protein N-myristoyltransferase (NMT), which attaches myristate, a rare 14-carbon saturated fatty acid, to an N-terminal glycine of some eukaryotic and virus proteins.	Glycine	239-246	N-myristoyltransferase 1	Homo sapiens	127-149
25471446-6	2015	Our results suggested that the glycine residues at positions 108 and 116 are important for the break of the helical structure of the membrane-inserting domain and the segment Thr93-Arg101 flanking the membrane-inserting domain may play a role in the self-association of the caveolin-1 protein at cellular membrane.	Glycine	31-38	caveolin 1	Homo sapiens	274-284
26558949-1	2015	Protein N-myristoylation is a ubiquitous cotranslational and posttranslational modification catalyzed by myristoyl CoA:protein N-myristoyltransferase (NMT), which attaches myristate, a rare 14-carbon saturated fatty acid, to an N-terminal glycine of some eukaryotic and virus proteins.	Glycine	239-246	N-myristoyltransferase 1	Homo sapiens	151-154
25212678-7	2014	In this study we show a new structural variant of alpha-chain, Hb Cibeles [alpha 25(B6) Gly   Asp], in heterozygous state, which was undetectable by electrophoretic or chromatographic methods.	Glycine	88-91	Fc gamma receptor and transporter	Homo sapiens	50-61
25342716-6	2015	We performed a forward genetic screen and identified eg200, a mutation that affects a conserved glycine in EAT-6, the alpha-subunit of the Na(+)/K(+) ATPase.	Glycine	96-103	Sodium/potassium-transporting ATPase subunit alpha	Caenorhabditis elegans	107-112
26226959-9	2015	Additionally, there were positive correlations between glycine and IL-1beta as well as glycine and IL-2, while negative correlation existed between C18:2 and TNF-alpha.	Glycine	87-94	interleukin-2	Ovis aries	99-103
25452338-5	2015	One linker position, glycine in NagC and arginine in Mlc, corresponds to the major specificity determinant for the two proteins.	Glycine	21-28	modulator of VRAC current 1	Homo sapiens	53-56
25452338-6	2015	In certain contexts it is possible to switch repression from Mlc-style to NagC-style, by interchanging this glycine and arginine.	Glycine	108-115	modulator of VRAC current 1	Homo sapiens	61-64
26599272-9	2015	GLDC can induce dramatic changes in glycolysis and glycine/serine metabolism, leading to changes in pyrimidine metabolism and tumor development.	Glycine	51-58	glycine decarboxylase	Mus musculus	0-4
25453086-8	2014	The N-terminal QGSY (glutamine-glycine-serine-tyrosine)-rich region (amino acids 1-164) mediates FUS self-assembly in the nucleus of mammalian cells and the self-assembly is essential for its chromatin binding and transcription activation.	Glycine	31-38	FUS RNA binding protein	Homo sapiens	97-100
25495193-11	2014	High Glycine levels were found in HER-2(pos) tumors, which support Glycine as potential marker for tumor aggressiveness.	Glycine	5-12	erb-b2 receptor tyrosine kinase 2	Homo sapiens	34-39
25399921-3	2014	Rodent Abeta (rAbeta) differs from human Abeta (hAbeta) only in the three substitutions of Arg to Gly, Tyr to Phe, and His to Arg at positions 5, 10, and 13, respectively.	Glycine	98-101	amyloid beta precursor protein	Homo sapiens	7-12
25817860-2	2015	NMDA receptors are a tetramer that consists of two glycine-binding subunits GluN1, two glutamate-binding subunits (i.e., GluN2A, GluN2B, GluN2C, and GluN2D), a combination of a GluN2 subunit and glycine-binding GluN3 subunit (i.e., GluN3A or GluN3B), or two GluN3 subunits.	Glycine	51-58	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	76-81
26205290-4	2015	Inhibition of GlyT1 reduces clearance of extra-cellular glycine near NMDA receptor-containing synapses, and thereby increases baseline occupancy of the glycine-B site at the NR1 subunit of the NMDA receptor, which is a prerequisite of channel activation upon stimulation by the excitatory neurotransmitter glutamate.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	14-19
26205290-4	2015	Inhibition of GlyT1 reduces clearance of extra-cellular glycine near NMDA receptor-containing synapses, and thereby increases baseline occupancy of the glycine-B site at the NR1 subunit of the NMDA receptor, which is a prerequisite of channel activation upon stimulation by the excitatory neurotransmitter glutamate.	Glycine	152-159	solute carrier family 6 member 9	Homo sapiens	14-19
26205290-4	2015	Inhibition of GlyT1 reduces clearance of extra-cellular glycine near NMDA receptor-containing synapses, and thereby increases baseline occupancy of the glycine-B site at the NR1 subunit of the NMDA receptor, which is a prerequisite of channel activation upon stimulation by the excitatory neurotransmitter glutamate.	Glycine	152-159	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	174-177
25245565-0	2015	Tryptophan to Glycine mutation in the position 116 leads to protein aggregation and decreases the stability of the LITAF protein.	Glycine	14-21	lipopolysaccharide induced TNF factor	Homo sapiens	115-120
25296192-1	2014	Human GPKOW [G-patch (glycine-rich) domain and KOW (Kyrpides, Ouzounis and Woese) domain] protein contains a G-patch domain and two KOW domains, and is a homologue of Arabidopsis MOS2 and Saccharomyces Spp2 protein.	Glycine	22-29	G-patch domain and KOW motifs	Homo sapiens	6-11
25823223-1	2014	N-myristoyltransferase (NMT) is an essential eukaryotic enzyme which catalyzes the transfer of the myristoyl group to the terminal glycine residue of a number of proteins including those involved in signal transduction and apoptotic pathways.	Glycine	131-138	N-myristoyltransferase 1	Homo sapiens	0-22
25823223-1	2014	N-myristoyltransferase (NMT) is an essential eukaryotic enzyme which catalyzes the transfer of the myristoyl group to the terminal glycine residue of a number of proteins including those involved in signal transduction and apoptotic pathways.	Glycine	131-138	N-myristoyltransferase 1	Homo sapiens	24-27
25375834-7	2014	Similarly, a natural substrate of MMP-2, Ace-Gln-Gly ~ Ile-Ala-Gly-Nme, can be converted to an inhibiting compound by two replacements, Ile by Cys and Gly by the d isomer of Cys, favoring formation of the zinc finger motif.	Glycine	49-52	angiotensin I converting enzyme	Homo sapiens	41-44
25244701-4	2014	Using the intrinsically disordered N-terminal region of the p53 protein as an experimental model, a set of proline (PRO) and alanine (ALA) to glycine (GLY) substitution variants were designed to modulate backbone conformational propensities without introducing non-native intramolecular interactions.	Glycine	142-149	tumor protein p53	Homo sapiens	60-63
25244701-4	2014	Using the intrinsically disordered N-terminal region of the p53 protein as an experimental model, a set of proline (PRO) and alanine (ALA) to glycine (GLY) substitution variants were designed to modulate backbone conformational propensities without introducing non-native intramolecular interactions.	Glycine	151-154	tumor protein p53	Homo sapiens	60-63
25375834-7	2014	Similarly, a natural substrate of MMP-2, Ace-Gln-Gly ~ Ile-Ala-Gly-Nme, can be converted to an inhibiting compound by two replacements, Ile by Cys and Gly by the d isomer of Cys, favoring formation of the zinc finger motif.	Glycine	63-66	angiotensin I converting enzyme	Homo sapiens	41-44
25375834-7	2014	Similarly, a natural substrate of MMP-2, Ace-Gln-Gly ~ Ile-Ala-Gly-Nme, can be converted to an inhibiting compound by two replacements, Ile by Cys and Gly by the d isomer of Cys, favoring formation of the zinc finger motif.	Glycine	63-66	angiotensin I converting enzyme	Homo sapiens	41-44
25313996-4	2014	X-ray cocrystallography revealed that upon binding of compound 4 to ERK2, Tyr34 undergoes a rotation (flip) along with a shift in the poly-Gly rich loop to create a new binding pocket into which 4 can bind.	Glycine	139-142	mitogen-activated protein kinase 1	Homo sapiens	68-72
25391026-6	2014	As prototypes, we focused on the precursor proteins of mature Substance P (SubP) and Cholecystokinin 4 (CCK4), specifically non-amidated SubP (SubP-COOH) and glycine extended CCK4 (CCK4-Gly-COOH).	Glycine	158-165	protein tyrosine kinase 7 (inactive)	Homo sapiens	175-179
25178856-7	2014	Further, the significant inhibition of the uptake of Gly-Sar by TRH analogs confirmed the PepT1-mediated transport mechanism.	Glycine	53-56	solute carrier family 15 member 1	Homo sapiens	90-95
25370744-4	2014	Melanoma-predisposing CDKN2A germline mutations, which affect conserved glycine and aspartate residues within the GHDDGQ motif, impair the ability of ARF to control superoxide production and suppress growth of melanoma cells in vivo.	Glycine	72-79	cyclin dependent kinase inhibitor 2A	Homo sapiens	22-28
24766780-3	2014	The combined (1)H-NMR spectroscopic and molecular dynamics methods were used to investigate the conformational behavior of an Arg-Gly-Asp (RGD)-containing peptide, GRGDSPC, the cell-binding heptapeptide of extracellular matrix protein, fibronectin.	Glycine	130-133	fibronectin 1	Homo sapiens	236-247
25205677-4	2014	Coapplication of 50 muM PYD-106 with a maximally effective concentration of glutamate and glycine increases the response of GluN1/GluN2C NMDA receptors in HEK-293 cells to 221% of that obtained in the absence of PYD (taken as 100%).	Glycine	90-97	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	124-129
26814446-4	2014	However, ELISA results showed that the Arg-Gly-Asp (RGD) activity of adsorbed Fn decreased with the increase of PHEMA thickness.	Glycine	43-46	fibronectin 1	Homo sapiens	78-80
25216398-0	2014	A Gly-zipper motif mediates homodimerization of the transmembrane domain of the mitochondrial kinase ADCK3.	Glycine	2-5	coenzyme Q8A	Homo sapiens	101-106
24654948-9	2014	Direct candidate gene sequencing revealed a heterozygous c. 335 G&gt;A variation in the beaded filament structural protein 2(BFSP2) gene, which resulted in the replacement of a highly conserved glycine by glutamic at codon 112 (p. G112E).	Glycine	194-201	beaded filament structural protein 2	Homo sapiens	125-130
24845614-5	2014	Inversely, HBV infection of PTH, PHH, and NTCP-transfected HepG2 cells was inhibited in a concentration-dependent manner by taurine and glycine conjugates of cholic acid and ursodeoxycholic acid as well as by ezetimibe.	Glycine	136-143	solute carrier family 10 member 1	Homo sapiens	42-46
25178856-4	2014	Inhibition experiments were carried out using Gly-Sar, a typical PepT1 substrate, to confirm the PepT1-mediated transport mechanism of TRH analogs.	Glycine	46-49	solute carrier family 15 member 1	Homo sapiens	65-70
25178856-4	2014	Inhibition experiments were carried out using Gly-Sar, a typical PepT1 substrate, to confirm the PepT1-mediated transport mechanism of TRH analogs.	Glycine	46-49	solute carrier family 15 member 1	Homo sapiens	97-102
25269793-4	2014	Our results show that the permeation activity of TD1-hEGF, a fusion protein composed of human epidermal growth factor (hEGF) and the TD1 sequence connected with a glycine-serine linker (GGGGS), can be inhibited by the energy inhibitor, rotenone or oligomycin.	Glycine	163-170	TLX1 neighbor	Homo sapiens	49-52
25269793-4	2014	Our results show that the permeation activity of TD1-hEGF, a fusion protein composed of human epidermal growth factor (hEGF) and the TD1 sequence connected with a glycine-serine linker (GGGGS), can be inhibited by the energy inhibitor, rotenone or oligomycin.	Glycine	163-170	TLX1 neighbor	Homo sapiens	133-136
25347266-7	2014	As determined from the spleen after the FST: Gly and Arg regulated the effects of IL-1beta; Gly, Pro, and Arg regulated the effects of IL-6; PE and all of the amino acids present in PE regulated the effects of TNF-alpha.	Glycine	45-48	interleukin 1 beta	Mus musculus	82-90
25347266-7	2014	As determined from the spleen after the FST: Gly and Arg regulated the effects of IL-1beta; Gly, Pro, and Arg regulated the effects of IL-6; PE and all of the amino acids present in PE regulated the effects of TNF-alpha.	Glycine	92-95	interleukin 6	Mus musculus	135-139
25347266-9	2014	As determined from the serum after the TST: PE and Gly regulated the effects of TNF-alpha; Gly and Arg regulated the effects of IL-1beta; Gly, Pro, and Arg regulated the effects of IL-6; PE and all of the amino acids present in PE regulated the effects of TNF-alpha.	Glycine	51-54	tumor necrosis factor	Mus musculus	80-89
25347266-9	2014	As determined from the serum after the TST: PE and Gly regulated the effects of TNF-alpha; Gly and Arg regulated the effects of IL-1beta; Gly, Pro, and Arg regulated the effects of IL-6; PE and all of the amino acids present in PE regulated the effects of TNF-alpha.	Glycine	91-94	interleukin 1 beta	Mus musculus	128-136
25347266-9	2014	As determined from the serum after the TST: PE and Gly regulated the effects of TNF-alpha; Gly and Arg regulated the effects of IL-1beta; Gly, Pro, and Arg regulated the effects of IL-6; PE and all of the amino acids present in PE regulated the effects of TNF-alpha.	Glycine	91-94	interleukin 1 beta	Mus musculus	128-136
25316790-3	2014	Here, we experimentally identify distinguishing attributes of ALS mutant SOD proteins that correlate with clinical severity by applying solution biophysical techniques to six ALS mutants at human SOD hotspot glycine 93.	Glycine	208-215	superoxide dismutase 1	Homo sapiens	73-76
25316790-3	2014	Here, we experimentally identify distinguishing attributes of ALS mutant SOD proteins that correlate with clinical severity by applying solution biophysical techniques to six ALS mutants at human SOD hotspot glycine 93.	Glycine	208-215	superoxide dismutase 1	Homo sapiens	196-199
25216398-6	2014	Our experimental analyses show that the transmembrane helix of ADCK3 oligomerizes, with an interface based on an extended Gly-zipper motif, as predicted by our models.	Glycine	122-125	coenzyme Q8A	Homo sapiens	63-68
24178590-8	2014	When FN molecules adsorbed onto the surfaces of TiNTs, their RGD (Arg-Gly-Asp) sites were easily exposed to outside and more likely to bond with the fibronectin receptors, in turn regulating the cellular behaviors.	Glycine	70-73	fibronectin 1	Homo sapiens	5-7
24178590-8	2014	When FN molecules adsorbed onto the surfaces of TiNTs, their RGD (Arg-Gly-Asp) sites were easily exposed to outside and more likely to bond with the fibronectin receptors, in turn regulating the cellular behaviors.	Glycine	70-73	fibronectin 1	Homo sapiens	149-160
25081482-4	2014	Mutated variants of the SR domains changing serine to glycine (SR-to-GR variants) also bound to hnRNPA2 hydrogels but were not affected by CLK1/2.	Glycine	54-61	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	96-103
25049229-8	2014	We suggest that a surface of GRK2, including Leu(4), Val(7), Leu(8), Val(11), and Ser(12), directly interacts with receptors, whereas residues such as Asp(10), Tyr(13), Ala(16), Met(17), Gly(475), Val(477), and Ile(485) are more important for kinase domain closure and activation.	Glycine	187-190	G protein-coupled receptor kinase 2	Homo sapiens	29-33
24571126-1	2014	Insulin glargine is processed in vivo into soluble 21(A) -Gly-human insulin (M1), the principal moiety responsible for metabolic effects, and subsequently into M2.	Glycine	58-61	insulin	Homo sapiens	0-7
24571126-1	2014	Insulin glargine is processed in vivo into soluble 21(A) -Gly-human insulin (M1), the principal moiety responsible for metabolic effects, and subsequently into M2.	Glycine	58-61	insulin	Homo sapiens	68-75
24850180-4	2014	The expression of several proteins involved in glycolysis, glutaminolysis, and serine/glycine metabolism was higher (p &lt; 0.01) in the AR- than in the AR+ group.	Glycine	86-93	androgen receptor	Homo sapiens	137-139
25017909-1	2014	Unlike GluN2-containing N-methyl-d-aspartate (NMDA) receptors, which require both glycine and glutamate for activation, receptors composed of GluN1 and GluN3 subunits are activated by glycine alone.	Glycine	184-191	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	142-147
25017909-4	2014	Isolated GluN1/GluN3A receptors integrated into lipid bilayers responded to addition of either glycine or d-serine, but not glutamate, with a ~1 nm reduction in height of the extracellular domain.	Glycine	95-102	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	9-14
25090004-0	2014	The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity.	Glycine	76-83	TAR DNA binding protein	Homo sapiens	69-75
25090004-2	2014	Later on, numerous ALS-related mutations were found in either the glycine or glutamine/asparagine-rich region on the TDP-43 C-terminus, which hinted on the importance of mutations on the disease pathogenesis.	Glycine	66-73	TAR DNA binding protein	Homo sapiens	117-123
25002580-2	2014	A hot spot for such clinical mutations is found at position B8, conserved as glycine within the vertebrate insulin superfamily.	Glycine	77-84	insulin	Homo sapiens	107-114
25002580-3	2014	We set out to investigate the molecular basis of the aberrant properties of a proinsulin clinical mutant in which residue Gly(B8) is replaced by Ser(B8).	Glycine	122-125	insulin	Homo sapiens	78-88
25002580-4	2014	Modular total chemical synthesis was used to prepare the wild-type [Gly(B8)]proinsulin molecule and three analogs: [D-Ala(B8)]proinsulin, [L-Ala(B8)]proinsulin, and the clinical mutant [L-Ser(B8)]proinsulin.	Glycine	68-71	insulin	Homo sapiens	76-86
24988361-5	2014	ABPP revealed that the sulfonamide glycine inhibitors have at least three off-targets, including alpha/beta-hydrolase domain 6 (ABHD6).	Glycine	35-42	amyloid beta precursor protein	Homo sapiens	0-4
24858859-7	2014	Dietary supplementation with 0.5, 1 and 2% glycine enhanced (P &lt; 0.05) small-intestinal villus height, glycine transport (measured using Ussing chambers), mRNA levels for GLYT1, and anti-oxidative capacity (indicated by increased concentrations of reduced glutathione and a decreased ratio of oxidized glutathione to reduced glutathione).	Glycine	43-50	solute carrier family 6 member 9	Homo sapiens	174-179
24803333-9	2014	The purpose of this study was to evaluate Scl-Ab in an adult 6 month old Brtl/+ model of OI that harbors a typical heterozygous OI-causing Gly &gt; Cys substitution on Col1a1.	Glycine	139-142	collagen, type I, alpha 1	Mus musculus	168-174
24850180-4	2014	The expression of several proteins involved in glycolysis, glutaminolysis, and serine/glycine metabolism was higher (p &lt; 0.01) in the AR- than in the AR+ group.	Glycine	86-93	androgen receptor	Homo sapiens	153-155
24874071-0	2014	An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease.	Glycine	45-52	leukotriene A4 hydrolase	Mus musculus	12-36
25076860-9	2014	Silencing the mutated androgen receptor (AR-599 Ser&gt;Gly) did not affect proliferation (loss-of-function), but decreased migration (gain-of-function) in E006AA-hT and its parental cell type.	Glycine	55-58	androgen receptor	Homo sapiens	22-39
24036283-1	2014	Glycine plays a key role in regulating inhibitory neurotransmission in the spinal cord and concentrations of glycine in the CNS are regulated by two subtypes of high affinity glycine transporters, GlyT1 and GlyT2.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	197-202
24333324-1	2014	Solute neutral amino acid transporter 5 (SNAT5/SN2) is a member of the System N family, expressed in glial cells in the adult brain, able to transport glutamine, histidine or glycine among other substrates.	Glycine	175-182	solute carrier family 38 member 5	Homo sapiens	41-46
24333324-1	2014	Solute neutral amino acid transporter 5 (SNAT5/SN2) is a member of the System N family, expressed in glial cells in the adult brain, able to transport glutamine, histidine or glycine among other substrates.	Glycine	175-182	solute carrier family 38 member 5	Homo sapiens	47-50
24333324-3	2014	Moreover, SNAT5/SN2 might contribute to the regulation of glycine concentration in glutamatergic synapses and, therefore, to the functioning of the N-methyl-d-aspartate (NMDA) subtype of glutamate receptors.	Glycine	58-65	solute carrier family 38 member 5	Homo sapiens	10-15
24333324-3	2014	Moreover, SNAT5/SN2 might contribute to the regulation of glycine concentration in glutamatergic synapses and, therefore, to the functioning of the N-methyl-d-aspartate (NMDA) subtype of glutamate receptors.	Glycine	58-65	solute carrier family 38 member 5	Homo sapiens	16-19
24036283-1	2014	Glycine plays a key role in regulating inhibitory neurotransmission in the spinal cord and concentrations of glycine in the CNS are regulated by two subtypes of high affinity glycine transporters, GlyT1 and GlyT2.	Glycine	109-116	solute carrier family 6 member 9	Homo sapiens	197-202
24948877-13	2014	Silencing of one of the somatic AR mutations (i.e., 597 Ser&gt;Gly) in a primary AA-PCa cell line (e.g., E006AA) revealed that similar AR mutation can be associated simultaneously with both "gain-of-function" phenotype (cell migration and invasion) and a "loss-of-function" phenotype (proliferation).	Glycine	63-66	androgen receptor	Homo sapiens	32-34
24979213-5	2014	GLDC, associated with glycine metabolism, was highly expressed in HER-2-positive MDA-MB-453 and TNBC-related MDA-MB-435S.	Glycine	22-29	erb-b2 receptor tyrosine kinase 2	Homo sapiens	66-71
24979213-11	2014	Expression of glycine-metabolism-associated proteins was high in the tumor and stroma of HER-2-positive cancers.	Glycine	14-21	erb-b2 receptor tyrosine kinase 2	Homo sapiens	89-94
24978476-8	2014	When ERRgamma-Asn346 was replaced by the corresponding Gly and Tyr in ERRalpha and ERRbeta, respectively, the binding affinity of BPA and even 4-hydroxytamxifen (4-OHT) is much reduced.	Glycine	55-58	estrogen related receptor alpha	Homo sapiens	70-78
24949742-6	2014	Type II collagen, encoded by the COL2A1 gene, contains N- and C- terminal regions that are cleaved after secretion into the extracellular matrix, and the core area is composed of a triple helical (Gly-X-Y) domain.	Glycine	197-200	collagen type II alpha 1 chain	Homo sapiens	33-39
24949742-11	2014	RESULT: In our research, we identify a heterozygous mutation (c.1888 G&gt;A, p. Gly630Ser) in exon 29 of COL2A1 in the Gly-X-Y domain, in a Chinese family affected by LCPD and ANFH.	Glycine	80-83	collagen type II alpha 1 chain	Homo sapiens	105-111
24459296-4	2014	We now demonstrate the existence of a new post-translational modification of HTT: the addition of the 14 carbon fatty acid myristate to a glycine residue exposed on a caspase-3-cleaved fragment (post-translational myristoylation) and that myristoylation of this fragment is altered in a physiologically relevant model of mutant HTT.	Glycine	138-145	caspase 3	Homo sapiens	167-176
24710069-7	2014	Modeling suggests that the two hydrogen bonds between the highly conserved residues Ser-528 and glycine-525 are required for PDRP-mediated phosphorylation of the active-site Thr-527 of PPDK.	Glycine	96-103	pyruvate, phosphate dikinase regulatory protein, chloroplastic	Zea mays	125-129
23775820-8	2014	Also, the simulations revealed different conformations of fibronectin on each scaffold type after adsorption, with the arginine-glycine-aspartic acid sequence appearing most accessible on the aminated scaffolds.	Glycine	128-135	fibronectin 1	Homo sapiens	58-69
24989301-2	2014	The binding ability of alpha-N-acetylgalactosaminidase with RBC in different reaction buffer such as alanine solution, glycine solution, normal saline (0.9% NaCl), PBS, PCS was detected by Western blot.	Glycine	119-126	alpha-N-acetylgalactosaminidase	Homo sapiens	23-54
24989301-4	2014	The evidences indicated that binding of enzyme with RBC was a key element for A to O blood group conversion, while the binding ability of alpha-N-acetylgalactosaminidase with RBC in alanine or glycine solution was similar.	Glycine	193-200	alpha-N-acetylgalactosaminidase	Homo sapiens	138-169
24904545-0	2014	Recoding of the stop codon UGA to glycine by a BD1-5/SN-2 bacterium and niche partitioning between Alpha- and Gammaproteobacteria in a tidal sediment microbial community naturally selected in a laboratory chemostat.	Glycine	34-41	defensin beta 1	Homo sapiens	47-52
24904545-7	2014	The enrichment of a member of the BD1-5/SN-2 candidate phylum enabled, for the first time, direct microscopic observation by fluorescent in situ hybridization and the experimental validation of the previously predicted translation of the stop codon UGA into glycine.	Glycine	258-265	defensin beta 1	Homo sapiens	34-39
24390398-10	2014	While there was no direct pro- or antiproliferative effect of either glycine or strychnine in both cell lines, glycine was shown to significantly decrease VEGF-A expression on mRNA and protein level up to 63 % in both cell lines.	Glycine	111-118	vascular endothelial growth factor A	Homo sapiens	155-161
24601881-9	2014	Induction of the SMAD2/3 pathway by ALK3 is dependent upon its own previous activation by associated type II receptors, which phosphorylate conserved serine and threonine residues in the ALK3 juxtamembrane glycine-serine-rich domain.	Glycine	206-213	SMAD family member 2	Mus musculus	17-24
24700805-9	2014	We demonstrated that reduced AGL enhances tumor growth by increasing glycine synthesis through increased expression of serine hydroxymethyltransferase 2.	Glycine	69-76	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	29-32
24828203-2	2014	The MALDI-ISD spectra of bovine serum albumin (BSA), myoglobin and thioredoxin show discontinuous intense ion peaks originating from one-side preferential cleavage at the N-Calpha bond of Xxx-Asp, Xxx-Asn, Xxx-Cys and Gly-Xxx residues.	Glycine	218-221	albumin	Homo sapiens	32-45
24648513-0	2014	Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).	Glycine	50-57	mechanistic target of rapamycin kinase	Homo sapiens	116-145
24648513-0	2014	Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).	Glycine	50-57	mechanistic target of rapamycin kinase	Homo sapiens	147-151
24674276-5	2014	The synaptically induced plateau potential and the Ca2+ elevation were blocked by 5,7-dichlorokynurenic acid (5,7-dCK), an antagonist for the glycine-binding sites of NMDAR.	Glycine	142-149	carbonic anhydrase 2	Rattus norvegicus	51-54
24736929-9	2014	DNA sequence analysis revealed a c.1636 G/A transition in exon 25 of the COL2A1 gene, which converted the codon GGT for glycine at position 546 to AGT, a codon for serine.	Glycine	120-127	collagen type II alpha 1 chain	Homo sapiens	73-79
24736929-9	2014	DNA sequence analysis revealed a c.1636 G/A transition in exon 25 of the COL2A1 gene, which converted the codon GGT for glycine at position 546 to AGT, a codon for serine.	Glycine	120-127	angiotensinogen	Homo sapiens	147-150
24390398-13	2014	Glycine decreases GlyR-dependent, VEGF-A-mediated, angiogenic signaling in human HCC and thus might be a promising additive to chemotherapy treatment strategies for highly vascularized tumors.	Glycine	0-7	vascular endothelial growth factor A	Homo sapiens	34-40
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	195-198	thioredoxin reductase 2	Homo sapiens	77-82
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	207-210	thioredoxin reductase 2	Homo sapiens	77-82
24361327-7	2014	The interaction interface of the docking model showed that the amino acids ASN 47, GLU 215, GLY 403 of GRP78 and THR 54, ASN 182 and HIS 184 of NF-kappaB are key residues involved in the docking.	Glycine	92-95	heat shock protein family A (Hsp70) member 5	Homo sapiens	103-108
24361327-7	2014	The interaction interface of the docking model showed that the amino acids ASN 47, GLU 215, GLY 403 of GRP78 and THR 54, ASN 182 and HIS 184 of NF-kappaB are key residues involved in the docking.	Glycine	92-95	nuclear factor kappa B subunit 1	Homo sapiens	144-153
24651281-3	2014	The majority of these mutations are found in the glycine-rich domain, including the variant M337V, which is one of the most common mutations in TDP-43.	Glycine	49-56	TAR DNA binding protein	Homo sapiens	144-150
24424027-4	2014	A mutation of the Tor2 glycine residue (G2040D) that lies adjacent to the key Torin-interacting tryptophan provides Torin1 resistance, confirming the specificity of Torin1 for TOR.	Glycine	23-30	peroxiredoxin 2	Homo sapiens	78-83
24412336-4	2014	Some amino acids namely arginine, glycine and histidine showed good retention of catalase functionality after spray drying and subsequent storage stress.	Glycine	34-41	catalase	Homo sapiens	81-89
24273061-3	2014	Glycine was reported to be costored with gamma-aminobutyric acid (GABA) in cerebellar interneurons that may coexpress glycine and GABA transporters, and this is confirmed here by confocal microscopy analysis showing coexpression of GAT1 and GlyT2 transporters on microtubule-associated protein-2-positive synaptosomes.	Glycine	0-7	solute carrier family 6 member 1	Homo sapiens	232-236
24188174-6	2014	Further, we demonstrate the ability of fibronectin and other plasma proteins to act through cell adhesion via the ubiquitous arginine-glycine-aspartic (RGD) motif to drive monocyte-to-DC differentiation, with high-density RGD substrates supporting 54 1 +- 5 8% differentiation via alphaVbeta3 and alpha5beta1integrin signalling.	Glycine	134-141	fibronectin 1	Homo sapiens	39-50
24273061-13	2014	In conclusion, GlyT2 transporters not only take up glycine to replenish synaptic vesicles but can also mediate release of GABA by reversal of GAT1 and permeation through anion channels.	Glycine	51-58	solute carrier family 6 member 1	Homo sapiens	142-146
24623205-5	2014	CONCLUSION: Our findings offer an opportunity for prediction of hypertension in elderly Lebanese individuals that carry a genetic combination of Asp/Asp genotype and Gly allele in eNOS and ADRB2 genes.	Glycine	166-169	nitric oxide synthase 3	Homo sapiens	180-184
23564381-2	2014	Glycine combines with the C-terminal of AM to form mature, physiologically active AM (mAM).	Glycine	0-7	activating transcription factor 7 interacting protein	Mus musculus	82-84
24373992-2	2014	At present study, we describe the effects of extracellularly applied cAMP and cGMP on glycine-induced chloride currents (I(Gly)) in isolated rat hippocampal pyramidal neurons.	Glycine	86-93	cathelicidin antimicrobial peptide	Rattus norvegicus	69-73
24373992-2	2014	At present study, we describe the effects of extracellularly applied cAMP and cGMP on glycine-induced chloride currents (I(Gly)) in isolated rat hippocampal pyramidal neurons.	Glycine	123-126	cathelicidin antimicrobial peptide	Rattus norvegicus	69-73
24373992-4	2014	cAMP and cGMP were co-applied with glycine.	Glycine	35-42	cathelicidin antimicrobial peptide	Rattus norvegicus	0-4
24184752-3	2014	In hPEPT2-HELA cells, entecavir uptake was significantly higher compared to vector-HELA cells and was sharply inhibited by Gly-sar and JBP485, and there were two distinct transport systems.	Glycine	123-126	solute carrier family 15 member 2	Homo sapiens	3-9
23564381-2	2014	Glycine combines with the C-terminal of AM to form mature, physiologically active AM (mAM).	Glycine	0-7	activating transcription factor 7 interacting protein	Mus musculus	86-89
24076356-8	2014	When comparing the myoglobin sequence from TA with the Ovis aries myoglobin sequence, variations were observed at codons 21 (GGT GAT) and 78 (GAA AAG), and these variations lead to changes in the corresponding amino acids, i.e., Gly Asp and Glu Lys, respectively.	Glycine	229-232	myoglobin	Pantholops hodgsonii	19-28
24551296-11	2014	), which is from an arginine codon (CGA) to a Glycine codon (GGA).	Glycine	46-53	chromogranin A	Homo sapiens	36-39
24130332-10	2014	Future studies are needed to determine whether Gly has a mechanistic role in glucose homeostasis and whether dietary Gly enrichment may be an effective intervention in diseases characterized by insulin resistance.	Glycine	117-120	insulin	Homo sapiens	194-201
24284322-3	2014	Here we show that the EBNA1-nucleophosmin interaction is direct and requires the Gly-Arg-rich sequences that contribute to transactivation.	Glycine	81-84	EBNA-1	Human gammaherpesvirus 4	22-27
24273251-1	2014	OBJECTIVE: The aim of this study was to develop an improved method for labelling ZHER2:342 with Technetium-99m ((99m)Tc) using Gly-(d) Ala-Gly-Gly as a chelator and to evaluate the feasibility of its use for visualization of HER2 expression in vivo.	Glycine	127-130	erb-b2 receptor tyrosine kinase 2	Homo sapiens	82-86
24383403-3	2014	Collagen prolyl-4-hydroxylase alpha subunit 2 (P4HA2), an enzyme hydroxylating proline residues in -X-Pro-Gly- sequences, is a potential therapeutic target for the disorders associated with increased collagen deposition.	Glycine	106-109	prolyl 4-hydroxylase subunit alpha 2	Homo sapiens	9-45
24383403-3	2014	Collagen prolyl-4-hydroxylase alpha subunit 2 (P4HA2), an enzyme hydroxylating proline residues in -X-Pro-Gly- sequences, is a potential therapeutic target for the disorders associated with increased collagen deposition.	Glycine	106-109	prolyl 4-hydroxylase subunit alpha 2	Homo sapiens	47-52
25399009-4	2014	According to PROSITE search result, active sites of c-erbB-2 are N-lobe (glycine rich phosphate binding loop).	Glycine	73-80	erb-b2 receptor tyrosine kinase 2	Homo sapiens	52-60
24803226-5	2014	In addition to Abeta peptides starting with an Asp at position 1, a variety of different N-truncated Abeta peptides have been identified starting with amino residue Ala-2, pyroglutamylated Glu-3, Phe-4, Arg-5, His-6, Asp-7, Ser-8, Gly-9, Tyr-10 and pyroglutamylated Glu-11.	Glycine	231-234	amyloid beta precursor protein	Homo sapiens	101-106
24292153-3	2014	Human fibrinogen is isolated from the plasma by the glycine precipitation method.	Glycine	52-59	fibrinogen beta chain	Homo sapiens	6-16
24273251-11	2014	Conculsion: (99m)Tc-peptide-ZHER2:342 using Gly-(d) Ala-Gly-Gly as a chelator is a promising tracer agent with favourable biodistribution and imaging properties that may be developed as a radiopharmaceutical for the detection of HER2-positive malignant tumours.	Glycine	44-47	erb-b2 receptor tyrosine kinase 2	Homo sapiens	29-33
23850894-5	2014	Site-directed mutagenesis experiments suggested that the domain centred around glycine 185 of Pgp was necessary for these inhibitory properties of DSPE-PEG and PEGylated neutral liposomes.	Glycine	79-86	ATP binding cassette subfamily B member 1	Homo sapiens	94-97
23742196-5	2014	Moreover, glycine increased the amount of Cu,Zn-SOD (copper/zinc superoxide dismutase) and eNOS (endothelial NO synthase) in aorta from SF animals.	Glycine	10-17	superoxide dismutase 1	Rattus norvegicus	42-51
23297802-6	2014	Despite these differences, there exists an interesting similarity between the two variants: both glutamates exert their function by modulating the conformation and interactions of glycine-rich motifs (G366-G367, G471-G473) resulting in an accumulation of binding incompetent gp120 conformations or a loss of intermolecular gp120-CD4 hydrogen bonds.	Glycine	180-187	CD4 molecule	Homo sapiens	329-332
25120925-0	2014	Interaction of ingested leucine with glycine on insulin and glucose concentrations.	Glycine	37-44	insulin	Homo sapiens	48-55
24330864-1	2013	A novel point mutation resulting in a glutamate-to-glycine substitution in PRNP at codon 200, E200G with codon 129 MV polymorphism (cis valine) and type 2 PrPSc was identified in a patient with a prolonged disease course leading to pathology-proven Jakob-Creutzfeldt disease.	Glycine	51-58	prion protein	Homo sapiens	75-79
24249225-2	2014	FMRP, which is proposed to be involved in the translational regulation of specific neuronal messenger RNA (mRNA) targets, contains an arginine-glycine-glycine (RGG) box RNA binding domain that has been shown to bind with high affinity to G-quadruplex forming mRNA structures.	Glycine	143-150	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
24249225-2	2014	FMRP, which is proposed to be involved in the translational regulation of specific neuronal messenger RNA (mRNA) targets, contains an arginine-glycine-glycine (RGG) box RNA binding domain that has been shown to bind with high affinity to G-quadruplex forming mRNA structures.	Glycine	151-158	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
24157939-3	2014	Research on ALS relies on transgenic models and particularly on mice carrying a glycine-to-alanine conversion at the 93rd codon (G93A) of the hSOD1 gene.	Glycine	80-87	superoxide dismutase 1	Homo sapiens	142-147
24391874-0	2013	Serum glycine is associated with regional body fat and insulin resistance in functionally-limited older adults.	Glycine	6-13	insulin	Homo sapiens	55-62
24391874-9	2013	In addition, because of the significant associations found between glycine with HOMA-IR, IMAT, SCAT and abdominal adiposity, our results suggest glycine as a serum biomarker of both insulin sensitivity and regional fat mass in functionally-limited older adults.	Glycine	145-152	insulin	Homo sapiens	182-189
24320595-7	2013	(Nature Genetics, 2010) using a pathway-based workflow (http://www.myexperiment.org/packs/319.html), confirmed previously identified hits and identified a new locus of human metabolic individuality, associating Aldehyde dehydrogenase family1 L1 (ALDH1L1) with serine/glycine ratios in blood.	Glycine	267-274	aldehyde dehydrogenase 1 family member L1	Homo sapiens	211-244
24320595-7	2013	(Nature Genetics, 2010) using a pathway-based workflow (http://www.myexperiment.org/packs/319.html), confirmed previously identified hits and identified a new locus of human metabolic individuality, associating Aldehyde dehydrogenase family1 L1 (ALDH1L1) with serine/glycine ratios in blood.	Glycine	267-274	aldehyde dehydrogenase 1 family member L1	Homo sapiens	246-253
24154564-3	2013	Indeed, it is well established that alphavbeta3 integrin plays a key role in tumor angiogenesis acting like a receptor for the extracellular matrix proteins like vitronectin, fibronectin through the arginine-glycine-aspartic acid (RGD) sequence.	Glycine	208-215	fibronectin 1	Homo sapiens	175-186
24140640-5	2013	The patient carried a heterozygous c.1316G &gt; A (p.Gly439Asp) mutation in the COL1A2 gene located in a triple-helix region, in which glycine substitutions have been assumed to cause perinatal lethal OI (Sillence type II).	Glycine	135-142	collagen type I alpha 2 chain	Homo sapiens	80-86
24048732-5	2013	The receptor tetramers in erythroid precursor cells are composed of the NR1, NR2A, 2C, 2D, NR3A, and 3B subunits of which the glycine-binding NR3A and 3B and glutamate-binding NR2C and 2D subunits prevailed.	Glycine	126-133	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	77-89
24032673-3	2013	In the present study, we show in neutrophil-activating chemokine CXCL8 that the highly conserved GP (glycine-proline) motif located distal to both N-terminal and N-loop residues couples Site-I and Site-II interactions.	Glycine	101-108	C-X-C motif chemokine ligand 8	Homo sapiens	65-70
24038317-7	2013	The double-belt conformations are modified by belt rotation, main-chain unhinging around Gly, and Pro-induced helical bending, and they are verified by comparison with previous experimental studies and by molecular dynamics simulations of apoA-I(Milano) homodimer.	Glycine	89-92	apolipoprotein A1	Homo sapiens	239-263
24268778-3	2013	Both the low-complexity domain and the arginine-glycine rich domain of FUS contribute to assembly.	Glycine	48-55	FUS RNA binding protein	Homo sapiens	71-74
23855983-3	2013	Here, we identified a neuroprotective pentapeptide anti-Abeta compound having the sequence of the glycine zipper region of the C-terminal of Abeta (G33LMVG37).	Glycine	98-105	amyloid beta precursor protein	Homo sapiens	56-61
23855983-3	2013	Here, we identified a neuroprotective pentapeptide anti-Abeta compound having the sequence of the glycine zipper region of the C-terminal of Abeta (G33LMVG37).	Glycine	98-105	amyloid beta precursor protein	Homo sapiens	141-146
23973313-1	2013	NMDA receptors are ligand-gated ion channels that assemble into tetrameric receptor complexes composed of glycine-binding GluN1 and GluN3 subunits (GluN3A-B) and glutamate-binding GluN2 subunits (GluN2A-D).	Glycine	106-113	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	122-127
23973313-2	2013	NMDA receptors can assemble as GluN1/N2 receptors and as GluN3-containing NMDA receptors, which are either glutamate/glycine-activated triheteromeric GluN1/N2/N3 receptors or glycine-activated diheteromeric GluN1/N3 receptors.	Glycine	117-124	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	150-155
23973313-2	2013	NMDA receptors can assemble as GluN1/N2 receptors and as GluN3-containing NMDA receptors, which are either glutamate/glycine-activated triheteromeric GluN1/N2/N3 receptors or glycine-activated diheteromeric GluN1/N3 receptors.	Glycine	117-124	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	150-155
23973313-3	2013	The glycine-binding GluN1 and GluN3 subunits display strikingly different pharmacological selectivity profiles.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	20-25
24072682-9	2013	H(+):Gly-Sar absorption was completely inhibited by cephalexin (a competitive inhibitor of PepT1) and was activated by GIP.	Glycine	5-8	gastric inhibitory polypeptide	Mus musculus	119-122
24259588-9	2013	Using the glycine-induced, NMDA-dependent form of chemical long-term potentiation (LTP) in cultured cortical neurons, we showed that CD3zeta was required for activity-dependent CaMKII autophosphorylation and for the synaptic recruitment of the AMPAR subunit GluA1.	Glycine	10-17	CD247 antigen	Mus musculus	133-140
24072682-10	2013	The GIP-activated Gly-Sar absorption was completely inhibited by RP-cAMP (a cAMP antagonist).	Glycine	18-21	gastric inhibitory polypeptide	Mus musculus	4-7
23962042-9	2013	The uptake of the hSGLT1 substrate [(14)C]-alpha-methyl-D-glycopyranoside and the hPepT1 substrate [(14)C]-Gly-Sar in Caco-2 cells was also decreased in the presence of 0.3 mM sertraline.	Glycine	107-110	solute carrier family 15 member 1	Homo sapiens	82-88
24121337-4	2013	Interestingly, the Gly-rich loop of CDK2 formed a beta-sheet that was different from that of MK2.	Glycine	19-22	amyloid beta precursor protein	Homo sapiens	48-54
24121337-5	2013	In MK2, TEI-I01800 changed the secondary structure of the Gly-rich loop from a beta-sheet to an alpha-helix by collision between Leu70 and a p-ethoxyphenyl group at the 7-position and bound to MK2.	Glycine	58-61	amyloid beta precursor protein	Homo sapiens	77-83
23856421-4	2013	Carbohydrate deficient transferrin testing showed a pattern pointing to a CDG type I. Sanger sequencing of DPM1 (dolichol-P-mannose synthase subunit 1) revealed a novel Gly &gt; Val change c.455G &gt; T missense mutation resulting in p.Gly152Val) of unknown pathogenicity and deletion/duplication analysis revealed an intragenic deletion from exons 3 to 7 on the other allele.	Glycine	169-172	transferrin	Homo sapiens	23-34
23972471-2	2013	GluN1 and GluN3 bind glycine, whereas GluN2 binds glutamate.	Glycine	21-28	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-5
24349641-0	2013	Effects of the Arg-Pro and Gly-Gly-Nle Moieties on Melanocortin-1 Receptor Binding Affinities of alpha-MSH Peptides.	Glycine	27-30	melanocortin 1 receptor	Mus musculus	51-74
24349641-0	2013	Effects of the Arg-Pro and Gly-Gly-Nle Moieties on Melanocortin-1 Receptor Binding Affinities of alpha-MSH Peptides.	Glycine	31-34	melanocortin 1 receptor	Mus musculus	51-74
24123150-1	2013	Patients with Parkinson"s disease (PD) who carry the G2019S mutation (a glycine to serine substitution at amino acid 2019) in the leucine-rich repeat kinase 2 (LRRK2) gene are generally believed to be clinically indistinguishable from patients with sporadic PD.	Glycine	72-79	leucine rich repeat kinase 2	Homo sapiens	130-158
23861372-4	2013	To generate a mouse model for the human disease, we have introduced an aspartic acid to glycine mutation in amino acid residue 582 (D582G) of the mouse LHR gene corresponding to the most common D578G mutation found in boys with familial male-limited precocious puberty (FMPP).	Glycine	88-95	luteinizing hormone/choriogonadotropin receptor	Mus musculus	152-155
23553550-11	2013	When NHE1 and AE2 activities were maintained in GV oocytes by exogenous expression, glycine accumulation was inhibited.	Glycine	84-91	solute carrier family 9 (sodium/hydrogen exchanger), member 1	Mus musculus	5-9
23553550-12	2013	We propose that NHE1-mediated acute cell volume regulation is inactivated during meiotic maturation to allow preferential accumulation of glycine in eggs.	Glycine	138-145	solute carrier family 9 (sodium/hydrogen exchanger), member 1	Mus musculus	16-20
24123150-1	2013	Patients with Parkinson"s disease (PD) who carry the G2019S mutation (a glycine to serine substitution at amino acid 2019) in the leucine-rich repeat kinase 2 (LRRK2) gene are generally believed to be clinically indistinguishable from patients with sporadic PD.	Glycine	72-79	leucine rich repeat kinase 2	Homo sapiens	160-165
23824820-6	2013	Mutation of the glycine residues in the consensus LRLRGG motif abolishes zf-ISG15 conjugation to these proteins and the cellular protection against viral infection, thus connecting ISGylation and ISG15-dependent viral restriction.	Glycine	16-23	ISG15 ubiquitin like modifier	Danio rerio	76-81
23962100-13	2013	The NMDA subunits NR2b and NR2a, in addition to the N-terminal region of the glycine binding NR1 subunit, have been implicated.	Glycine	77-84	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	93-96
23623897-3	2013	We identified that treatment with collagen hydrolysate or Gly repressed the expression of the mesendodermal markers, Brachyury and Foxa2 in EBs and maintained the undifferentiated state of mESCs in a feeder-free monolayer culture.	Glycine	58-61	brachyury, T-box transcription factor T	Mus musculus	117-126
23623897-3	2013	We identified that treatment with collagen hydrolysate or Gly repressed the expression of the mesendodermal markers, Brachyury and Foxa2 in EBs and maintained the undifferentiated state of mESCs in a feeder-free monolayer culture.	Glycine	58-61	forkhead box A2	Mus musculus	131-136
24046420-5	2013	At d 35, an interaction (P &lt;= 0.01) was observed between the Gly+Ser and dig Thr levels for G:F. Glycine supplementation resulted in a linear increase (P &lt; 0.05) in BW gain, G:F, intestinal mucin secretion, apparent digestibility of fat, and AME values of the experimental diets.	Glycine	100-107	mucin 2, oligomeric mucus/gel-forming	Gallus gallus	196-201
24106408-7	2013	Underlying mechanism was exploited by linear correlation between AUC values of Gly and existed iNOS in portal triads.	Glycine	79-82	nitric oxide synthase 2	Rattus norvegicus	95-99
24106408-11	2013	Gly does dose-dependently reduce PHT in IPPRLs with CCl4-induced chronic hepatitis.	Glycine	0-3	C-C motif chemokine ligand 4	Rattus norvegicus	52-56
24106408-15	2013	AUC values of Gly were positively correlated with existed iNOS levels in portal triads.	Glycine	14-17	nitric oxide synthase 2	Rattus norvegicus	58-62
24106408-16	2013	CONCLUSION: Gly reduces indirectly PHT in IPPRL with CCl4-induced chronic hepatitis.	Glycine	12-15	C-C motif chemokine ligand 4	Rattus norvegicus	53-57
23924183-6	2013	Both inhibition of cyclooxygenase-2 and antagonism at the glycine-binding site of the NMDA receptor prevented the glutamate-mediated induction of P-glycoprotein transport function in human capillaries.	Glycine	58-65	ATP binding cassette subfamily B member 1	Homo sapiens	146-160
23924183-8	2013	Targeting of cyclooxygenase-2 and of the NMDA receptor glycine-binding site was confirmed as an efficacious approach to control P-glycoprotein function.	Glycine	55-62	ATP binding cassette subfamily B member 1	Homo sapiens	128-142
23824820-6	2013	Mutation of the glycine residues in the consensus LRLRGG motif abolishes zf-ISG15 conjugation to these proteins and the cellular protection against viral infection, thus connecting ISGylation and ISG15-dependent viral restriction.	Glycine	16-23	ISG15 ubiquitin like modifier	Danio rerio	196-201
23635657-2	2013	FUS contains a methylated arginine-glycine-glycine domain that is required for transport into the nucleus.	Glycine	35-42	FUS RNA binding protein	Homo sapiens	0-3
23635657-2	2013	FUS contains a methylated arginine-glycine-glycine domain that is required for transport into the nucleus.	Glycine	43-50	FUS RNA binding protein	Homo sapiens	0-3
23941530-0	2013	Identification of a single amino acid in GluN1 that is critical for glycine-primed internalization of NMDA receptors.	Glycine	68-75	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	41-46
23986260-6	2013	GlyT2 cotransports 3Na+/Cl-/glycine generating large rises of Na+ inside the presynaptic terminal that must be efficiently reduced by the NKA to preserve Na+ homeostasis.	Glycine	28-35	tachykinin precursor 1	Homo sapiens	138-141
23909910-2	2013	Several members of this class inhibit NMDA receptor responses in the nanomolar range and are more than 50-fold selective over GluN1/GluN2A and GluN1/GluN2B NMDA receptors, as well as AMPA, kainate, GABA, glycine, nicotinic, serotonin, and purinergic receptors.	Glycine	204-211	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	126-131
23909910-2	2013	Several members of this class inhibit NMDA receptor responses in the nanomolar range and are more than 50-fold selective over GluN1/GluN2A and GluN1/GluN2B NMDA receptors, as well as AMPA, kainate, GABA, glycine, nicotinic, serotonin, and purinergic receptors.	Glycine	204-211	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	132-138
23909910-2	2013	Several members of this class inhibit NMDA receptor responses in the nanomolar range and are more than 50-fold selective over GluN1/GluN2A and GluN1/GluN2B NMDA receptors, as well as AMPA, kainate, GABA, glycine, nicotinic, serotonin, and purinergic receptors.	Glycine	204-211	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	143-148
23814066-8	2013	In contrast, mouse Ctrc readily cleaved the Phe-150-Gly-151 peptide bond in the autolysis loop of T8 and T9 and inhibited autoactivation.	Glycine	52-55	chymotrypsin C (caldecrin)	Mus musculus	19-23
24137498-6	2013	We therefore designed a peptide with two glycine "hinges" replacing residues I14 and V15, of the wild-type Bcl-2-BH4 domain (Bcl-2-BH4-IV/GG).	Glycine	41-48	BCL2 apoptosis regulator	Homo sapiens	107-112
23833192-4	2013	FUS recruitment is mediated by the arginine/glycine-rich domains, which interact directly with PAR.	Glycine	44-51	FUS RNA binding protein	Homo sapiens	0-3
23836915-3	2013	EBNA1 localizes to cellular chromosomes (chromatin) via its chromosome binding domains (CBDs), which are rich in glycine and arginine residues.	Glycine	113-120	EBNA-1	Human gammaherpesvirus 4	0-5
23941530-4	2013	RESULTS: Here we address the key issue of identifying molecular determinants in the glycine-binding subunit, GluN1, that are essential for priming of NMDA receptors.	Glycine	84-91	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	109-114
23941530-6	2013	However, with a glycine-binding mutant of GluN1 - N710R/Y711R/E712A/A714L - we found that treating with glycine did not promote recruitment of AP-2 nor were glycine-treated receptors internalized when subsequently activated with NMDA plus glycine.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	42-47
23941530-6	2013	However, with a glycine-binding mutant of GluN1 - N710R/Y711R/E712A/A714L - we found that treating with glycine did not promote recruitment of AP-2 nor were glycine-treated receptors internalized when subsequently activated with NMDA plus glycine.	Glycine	104-111	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	42-47
23941530-6	2013	However, with a glycine-binding mutant of GluN1 - N710R/Y711R/E712A/A714L - we found that treating with glycine did not promote recruitment of AP-2 nor were glycine-treated receptors internalized when subsequently activated with NMDA plus glycine.	Glycine	104-111	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	42-47
23941530-6	2013	However, with a glycine-binding mutant of GluN1 - N710R/Y711R/E712A/A714L - we found that treating with glycine did not promote recruitment of AP-2 nor were glycine-treated receptors internalized when subsequently activated with NMDA plus glycine.	Glycine	104-111	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	42-47
23941530-9	2013	CONCLUSIONS: Thus, we have identified a single amino acid in GluN1 that is critical for priming of NMDA receptors by glycine.	Glycine	117-124	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	61-66
24209971-5	2013	By using genomic DNA from dogs of various breeds with and without ITP, sequencing of PCR products encompassing all coding regions and exon-intron boundaries for these 3 genes revealed 4 single-nucleotide polymorphisms in ITGA2B resulting in amino acid polymorphisms in the canine genome, 3 previously reported and 1 newly identified (Gly[GGG]/Arg[AGG] at amino acid position 576 of ITGA2B.	Glycine	334-337	integrin subunit alpha 2b	Canis lupus familiaris	221-227
23740269-4	2013	GGT AAT substitution resulted in Gly Asn change inside the zinc-finger motif in the capsid protein was revealed specific for discrimination of the clusters and we hypothesise that could influence the host preference.	Glycine	33-36	serpin family A member 1	Homo sapiens	4-7
23772836-1	2013	The HLA-A*33:44 allele differs from HLA-A*33:03:01 by a single mutation at position 866 (G A), at codon 265 (GGT GAT) in exon4 (Gly Asp).	Glycine	128-131	major histocompatibility complex, class I, A	Homo sapiens	4-9
23772836-1	2013	The HLA-A*33:44 allele differs from HLA-A*33:03:01 by a single mutation at position 866 (G A), at codon 265 (GGT GAT) in exon4 (Gly Asp).	Glycine	128-131	major histocompatibility complex, class I, A	Homo sapiens	36-41
23936142-1	2013	Glycine N-methyltransferase (GNMT), an abundant cytosolic enzyme, catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to glycine generating S-adenosylhomocysteine and sarcosine (N-methylglycine).	Glycine	142-149	glycine N-methyltransferase	Homo sapiens	0-27
23936142-1	2013	Glycine N-methyltransferase (GNMT), an abundant cytosolic enzyme, catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to glycine generating S-adenosylhomocysteine and sarcosine (N-methylglycine).	Glycine	142-149	glycine N-methyltransferase	Homo sapiens	29-33
23922881-6	2013	We hypothesized that PIMT plays a critical role in gly-LDL induced VEC apoptosis; grape seed procyanidin B2 (GSPB2) protect against gly-LDL induced VEC apoptosis through PIMT regulation.	Glycine	51-54	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1	Rattus norvegicus	21-25
23922881-9	2013	Mechanistically, overexpression of PIMT or GSPB2 increased the phosphorylation of ERK1/2 and GSK3beta in the gly-LDL induced VEC.	Glycine	109-112	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1	Rattus norvegicus	35-39
23922881-10	2013	CONCLUSION: In summary, our study identified PIMT as a key player responsible for gly-LDL induced VEC apoptosis and GSPB2 protect against gly-LDL induced VEC apoptosis by PIMT up-regulation.	Glycine	82-85	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1	Rattus norvegicus	45-49
23756814-2	2013	Substitution of glycine at the position 45 of Cx26 to glutamic acid (p.G45E mutation) causes the Keratitis-ichthyosis-deafness (KID) syndrome.	Glycine	16-23	gap junction protein beta 2	Homo sapiens	46-50
23828687-3	2013	In a bicyclic peptide inhibitor of the cancer-related protease urokinase-type plasminogen activator (uPA), we observed a glycine residue that has a positive phi dihedral angle when bound to the target.	Glycine	121-128	plasminogen activator, urokinase	Homo sapiens	63-99
23828687-3	2013	In a bicyclic peptide inhibitor of the cancer-related protease urokinase-type plasminogen activator (uPA), we observed a glycine residue that has a positive phi dihedral angle when bound to the target.	Glycine	121-128	plasminogen activator, urokinase	Homo sapiens	101-104
23961398-3	2013	A flexible region between Leu-13 and Gly-15 is identified for TMD11-32 and a region around Gly-46 to Trp-48 for TMD236-58.	Glycine	37-40	interferon induced transmembrane protein 1	Homo sapiens	26-32
23449734-8	2013	Interestingly, the integrin-blocking peptide Arg-Gly-Asp-Ser, as well as integrin alpha5beta1 function-blocking antibodies, inhibited the effects of TGF-beta1 and its combination with methacholine on cell proliferation.	Glycine	49-52	transforming growth factor beta 1	Homo sapiens	149-158
23717658-9	2013	One over-represented peptide that recognizes StPTB6 contains the GVLGPWP sequence that is similar to the GIGGRYP sequence in the glycine-rich linker region between the KH2 and KH3 domains of StNova1.	Glycine	129-136	polypyrimidine tract-binding protein homolog 3-like	Solanum tuberosum	45-51
23523930-6	2013	Although the mRNA levels were only slightly affected by the mutations, the amount of Ncb5or protein was largely reduced upon two Glu to Gly replacements in the third exon (p.E87G, p.E93G).	Glycine	136-139	cytochrome b5 reductase 4	Homo sapiens	85-91
23466546-5	2013	Then, insulin was removed from the cryogel by using 0.1 M glycine-HCl buffer (pH: 3.5).	Glycine	58-69	insulin	Homo sapiens	6-13
23549681-4	2013	However, in MDA-MB-231 cells (expressing high prolidase activity) cultured in the presence of prolidase substrates, Gly-Pro or Gly-HyPro, HIF-1alpha expression was induced in a dose-dependent manner, independently of estrogen receptor activation.	Glycine	116-119	hypoxia inducible factor 1 subunit alpha	Homo sapiens	138-148
23549681-4	2013	However, in MDA-MB-231 cells (expressing high prolidase activity) cultured in the presence of prolidase substrates, Gly-Pro or Gly-HyPro, HIF-1alpha expression was induced in a dose-dependent manner, independently of estrogen receptor activation.	Glycine	116-119	estrogen receptor 1	Homo sapiens	217-234
23697369-6	2013	Apigenin binds to the C-terminal glycine-rich domain of hnRNPA2, preventing hnRNPA2 from forming homodimers, and therefore, it perturbs the alternative splicing of several human hnRNPA2 targets.	Glycine	33-40	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	56-63
23378610-0	2013	Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.	Glycine	33-40	insulin	Homo sapiens	70-77
23466492-3	2013	In this study, we report that alpha-actinin-4 is initially cleaved by m-calpain between tyrosine 13 and glycine.	Glycine	104-111	calpain 2	Homo sapiens	70-79
24498605-7	2013	We newly identified three mutations: two mutations in highly conserved Gly-Phe-Phe-Lys-Arg sequence in juxtamembrane region of alphaIIb, p.Gly991Cys and p.Phe993del, and one donor site mutation of intron 13 of ITGB3 leading to 40 amino acids deletion, p.(Asp621_Glu660del), in the membrane proximal beta-tail domain of beta3.	Glycine	71-74	integrin subunit beta 3	Homo sapiens	210-215
23485803-4	2013	The enhancement was blocked by the NMDAR glycine site antagonist 5,7-dichlorokynurenic acid, glycine saturation, and infusion of astrocytes with D-amino acid oxidase and the serine racemase inhibitor L-erythro-3-hydroxyaspartate, suggesting the involvement of astrocytic D-serine release.	Glycine	41-48	serine racemase	Rattus norvegicus	174-189
23632022-5	2013	This has identified a sequence of residues in the cytosolic cavity-lining transmembrane helix of RyR (G(4864)LIIDA(4869) in RyR2) analogous to the glycine hinge motif present in many K(+) channels.	Glycine	147-154	ryanodine receptor 2	Homo sapiens	97-100
23632022-5	2013	This has identified a sequence of residues in the cytosolic cavity-lining transmembrane helix of RyR (G(4864)LIIDA(4869) in RyR2) analogous to the glycine hinge motif present in many K(+) channels.	Glycine	147-154	ryanodine receptor 2	Homo sapiens	124-128
23720861-16	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	fibrinogen beta chain	Homo sapiens	44-54
23445487-6	2013	Transgenic lines over-expressing PCaP2, PCaP2(G2A) (second glycine substituted by alanine) and  23PCaP2 (lacking the N23 domain) exhibited abnormal branched and bulbous root hair cells, while over-expression of the N23 domain suppressed root hair emergence and elongation.	Glycine	59-66	microtubule-associated protein 18	Arabidopsis thaliana	33-38
23704982-6	2013	Homology models of Caenorhabditis elegans Tgt and human Tgt suggest that the replacement of Cys158 and Val233 in bacterial Tgt (Zymomonas mobilis Tgt numbering) by valine and accordingly glycine in eucaryotic Tgt largely accounts for the different substrate specificities.	Glycine	187-194	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	42-45
23704982-6	2013	Homology models of Caenorhabditis elegans Tgt and human Tgt suggest that the replacement of Cys158 and Val233 in bacterial Tgt (Zymomonas mobilis Tgt numbering) by valine and accordingly glycine in eucaryotic Tgt largely accounts for the different substrate specificities.	Glycine	187-194	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	56-59
23704982-6	2013	Homology models of Caenorhabditis elegans Tgt and human Tgt suggest that the replacement of Cys158 and Val233 in bacterial Tgt (Zymomonas mobilis Tgt numbering) by valine and accordingly glycine in eucaryotic Tgt largely accounts for the different substrate specificities.	Glycine	187-194	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	56-59
23704982-6	2013	Homology models of Caenorhabditis elegans Tgt and human Tgt suggest that the replacement of Cys158 and Val233 in bacterial Tgt (Zymomonas mobilis Tgt numbering) by valine and accordingly glycine in eucaryotic Tgt largely accounts for the different substrate specificities.	Glycine	187-194	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	56-59
23580486-7	2013	RESULTS: An A to G missense mutation at position 518 of the Gnat2 gene was identified that resulted in an aspartic acid to glycine substitution.	Glycine	123-130	guanine nucleotide binding protein, alpha transducing 2	Mus musculus	60-65
23562395-5	2013	Loss of Rpt6"s partially unfolded state by glycine substitution (Rpt6 G360,387A) disrupts holoenzyme formation in vitro, an effect enhanced by Rpn14.	Glycine	43-50	Rpn14p	Saccharomyces cerevisiae S288C	143-148
23103539-13	2013	At day-14 post ligation, glycine treatment also ameliorated liver damage indicated by serum AST (p&lt;0.005), ALT (p&lt;0.05) and hepatic caspase 3 activities (p&lt;0.05) and oxidative stress.	Glycine	25-32	solute carrier family 17 member 5	Homo sapiens	92-95
23103539-13	2013	At day-14 post ligation, glycine treatment also ameliorated liver damage indicated by serum AST (p&lt;0.005), ALT (p&lt;0.05) and hepatic caspase 3 activities (p&lt;0.05) and oxidative stress.	Glycine	25-32	caspase 3	Homo sapiens	138-147
23642268-7	2013	Three identified proteins: splicing factor, proline- and glutamine-rich (SFPQ), heterogeneous nuclear ribonucleoprotein D-like (hnRNP DL) and cellular nucleic acid binding protein (CNBP) are known to contain methylarginines in their glycine and arginine rich (GAR) sequences.	Glycine	233-240	splicing factor proline and glutamine rich	Homo sapiens	27-71
23642268-7	2013	Three identified proteins: splicing factor, proline- and glutamine-rich (SFPQ), heterogeneous nuclear ribonucleoprotein D-like (hnRNP DL) and cellular nucleic acid binding protein (CNBP) are known to contain methylarginines in their glycine and arginine rich (GAR) sequences.	Glycine	233-240	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	80-126
23642268-7	2013	Three identified proteins: splicing factor, proline- and glutamine-rich (SFPQ), heterogeneous nuclear ribonucleoprotein D-like (hnRNP DL) and cellular nucleic acid binding protein (CNBP) are known to contain methylarginines in their glycine and arginine rich (GAR) sequences.	Glycine	233-240	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	128-136
23116563-2	2013	By candidate gene screening, we identified a novel mutation in MIP (c.494 G &gt; A) that segregates with a congenital lamellar cataract within a south Indian family and causes the replacement of a highly conserved glycine by aspartate (G165D) within aquaporin0 (AQP0).	Glycine	214-221	major intrinsic protein of lens fiber	Homo sapiens	250-260
23116563-2	2013	By candidate gene screening, we identified a novel mutation in MIP (c.494 G &gt; A) that segregates with a congenital lamellar cataract within a south Indian family and causes the replacement of a highly conserved glycine by aspartate (G165D) within aquaporin0 (AQP0).	Glycine	214-221	major intrinsic protein of lens fiber	Homo sapiens	262-266
23116563-5	2013	These results suggest that mutation of this conserved glycine residue leads to improper trafficking of AQP0-G165D and loss of water channel function.	Glycine	54-61	major intrinsic protein of lens fiber	Homo sapiens	103-107
28516014-7	2013	We designed this approach and then validated its efficacy using a 24 amino acid minimum binding region of the intrinsically disordered, neuron-specific substrates, Neurogranin and Neuromodulin, joined via a Gly-linker to their interacting partner, Calmodulin.	Glycine	207-210	calmodulin 1	Homo sapiens	248-258
23509275-6	2013	UGA appears not to function as a stop codon and is in equilibrium with the canonical GGN glycine codons, displaying strain-specific variation across the human population.	Glycine	89-96	gametogenetin	Homo sapiens	85-88
23089362-7	2013	Synaptic GluN2A-containing and extrasynaptic GluN2B-containing NMDARs have different co-agonists: d-serine for synaptic NMDARs and glycine for extrasynaptic NMDARs.	Glycine	131-138	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	9-15
23372158-2	2013	The pathogenic forms of TDP-43 are processed C-terminal fragments containing a truncated RNA-recognition motif (RRM2) and a glycine-rich region.	Glycine	124-131	TAR DNA binding protein	Homo sapiens	24-30
23372158-4	2013	Here, using size-exclusion chromatography, pulldown assays, and small angle x-ray scattering, we show that the C-terminal-deleted TDP-43 without the glycine-rich tail is sufficient to form a head-to-head homodimer primarily via its N-terminal domain.	Glycine	149-156	TAR DNA binding protein	Homo sapiens	130-136
23280365-5	2013	The structural basis for this discrepancy was identified as a single amino acid variation between hCD1d and mCD1d, a glycine-to-tryptophan modification within the alpha2-helix that prevents flattening of the iGb3 headgroup upon TCR ligation.	Glycine	117-124	CD1d1 antigen	Mus musculus	108-113
23521792-3	2013	Here, we show that the Arg-Gly-Gly domain in the C-terminal region of TLS forms a ternary complex with human telomere G-quadruplex DNA and TERRA in vitro.	Glycine	27-30	FUS RNA binding protein	Homo sapiens	70-73
23521792-3	2013	Here, we show that the Arg-Gly-Gly domain in the C-terminal region of TLS forms a ternary complex with human telomere G-quadruplex DNA and TERRA in vitro.	Glycine	31-34	FUS RNA binding protein	Homo sapiens	70-73
23486948-4	2013	We find that the plasma membrane transporter GlyT2 and the intracellular enzyme glutamate decarboxylase supply the majority of glycine and GABA, respectively.	Glycine	127-134	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	80-103
23380375-2	2013	Optimization of the benzamide and central ring components of the core scaffold led to the identification of a GlyT-1 inhibitor that demonstrated in vivo activity in a rodent cerebral spinal fluid (CSF) glycine model.	Glycine	202-209	solute carrier family 6 member 9	Homo sapiens	110-116
23280365-5	2013	The structural basis for this discrepancy was identified as a single amino acid variation between hCD1d and mCD1d, a glycine-to-tryptophan modification within the alpha2-helix that prevents flattening of the iGb3 headgroup upon TCR ligation.	Glycine	117-124	alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)	Mus musculus	208-212
23334161-1	2013	Cytochrome c is a highly conserved protein, with 20 residues identical in all eukaryotic cytochromes c. Gly-41 is one of these invariant residues, and is the position of the only reported naturally occurring mutation in cytochrome c (human G41S).	Glycine	104-107	cytochrome c, somatic	Homo sapiens	0-12
23334161-1	2013	Cytochrome c is a highly conserved protein, with 20 residues identical in all eukaryotic cytochromes c. Gly-41 is one of these invariant residues, and is the position of the only reported naturally occurring mutation in cytochrome c (human G41S).	Glycine	104-107	cytochrome c, somatic	Homo sapiens	220-232
23415437-4	2013	APOA-I gene sequencing revealed a novel heterozygous in-frame insertion mutation with duplication of nucleotides 1535 through 1552 inserted at position 1553, causing a new amino acid glycine at codon 157 and a duplication of amino acids alanine, arginine, alanine, histidine, and leucine at codons 158-162.	Glycine	183-190	apolipoprotein A1	Homo sapiens	0-6
23373819-1	2013	A recent ion mobility-mass spectrometry (IM-MS) study of the nonapeptide bradykinin (BK, amino acid sequence Arg(1)-Pro(2)-Pro(3)-Gly(4)-Phe(5)-Ser(6)-Pro(7)-Phe(8)-Arg(9)) found evidence for 10 populations of conformations that depend upon the solution composition [J.	Glycine	130-133	kininogen 1	Homo sapiens	73-83
23358825-5	2013	The remodeling function is mediated by a bipartite Gly-Arg rich domain of EBNA1 that resembles the AT-hook of High Mobility Group A (HMGA) architectural transcription factors.	Glycine	51-54	EBNA-1	Human gammaherpesvirus 4	74-79
23452855-3	2013	Cloning of a short-period circadian mutant, Past-time, revealed a glycine to glutamate missense mutation in Fbxl21, an F-box protein gene that is a paralog of Fbxl3 that targets the CRY proteins for degradation.	Glycine	66-73	F-box and leucine rich repeat protein 21, pseudogene	Homo sapiens	108-114
23010016-3	2013	Optimal pH and temperature were rapidly found by successive and alternate injections of AFP and the regeneration solution (glycine-HCl, pH 1.5) onto the anti-AFP immobilized sensor chip.	Glycine	123-134	alpha fetoprotein	Homo sapiens	158-161
24358882-0	2013	Glycine-extended gastrin enhances somatostatin release from cultured rabbit fundic D-cells.	Glycine	0-7	gastrin	Oryctolagus cuniculus	17-24
23203508-3	2013	The latter dipeptide is a substrate of leucyl aminopeptidase, which hydrolyzes cysteinylglycine to glycine and cysteine that can be easily measured spectrophotometrically.	Glycine	88-95	leucine aminopeptidase 3	Homo sapiens	39-60
23247893-1	2013	The structure and vibrational spectra of a marginally stable conformer of glycine (usually referred to as VIp or ttc) recently detected in low-temperature matrices have been characterized by a state-of-the-art computational approach allowing an overall quality for bond distances, rotational constants, conformational enthalpies and vibrational frequencies well within the chemical accuracy.	Glycine	74-81	vasoactive intestinal peptide	Homo sapiens	106-109
23484211-2	2013	Based on these estimations, a three-dimensional model of Lys-Glu and Ala-Glu-Asp-Gly peptide interactions with DNA sites (GCAG and ATTTC) located in the promoter zones of genes encoding CD5, IL-2, MMP2, and Tram1 signal molecules.	Glycine	81-84	interleukin 2	Homo sapiens	191-195
23151080-0	2013	Membrane insertion of new AMPA receptors and LTP induced by glycine is prevented by blocking NR2A-containing NMDA receptors in the rat visual cortex in vitro.	Glycine	60-67	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	93-97
23151080-2	2013	However, the contribution of NR2A and NR2B subunits in glycine-induced long-term potentiation (LTP) of miniature excitatory postsynaptic currents (mEPSCs) in layer II/III pyramidal neurons of the rat visual cortex remains unclear.	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	29-33
23151080-7	2013	However, Zn2+, a voltage-independent NR2A-containing NMDA-R antagonist, prevented glycine-induced LTP.	Glycine	82-89	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	37-41
23151080-8	2013	These results suggest that the glycine-induced LTP in layer II/III pyramidal neurons of the rat visual cortex is NMDA-R-dependent and requires NR2A-containing NMDA-Rs, not NR2B-containing NMDA-Rs.	Glycine	31-38	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	143-147
23132267-2	2013	An approach for normalizing glutamate neurotransmission by enhancing NMDA receptor transmission is to increase glycine availability by inhibiting the glycine transporter type 1 (GlyT1).	Glycine	111-118	solute carrier family 6 member 9	Homo sapiens	150-176
23132267-2	2013	An approach for normalizing glutamate neurotransmission by enhancing NMDA receptor transmission is to increase glycine availability by inhibiting the glycine transporter type 1 (GlyT1).	Glycine	111-118	solute carrier family 6 member 9	Homo sapiens	178-183
23132267-3	2013	This study investigated the relationship between the plasma concentration of the glycine reuptake inhibitor bitopertin (RG1678) and brain GlyT1 occupancy.	Glycine	81-88	solute carrier family 6 member 9	Homo sapiens	138-143
23261437-1	2013	Epstein-Barr Virus Nuclear Antigen (EBNA) 2 features an Arginine-Glycine repeat (RG) domain at amino acid positions 335-360, which is a known target for protein arginine methyltransferaser 5 (PRMT5).	Glycine	65-72	protein arginine methyltransferase 5	Homo sapiens	192-197
23030311-8	2013	RESULTS: The activity of alpha-N-acetylgalactosaminidase and alpha-galactosidase was not decreased drastically when they were kept in PCS Buffer in 4 C. The optimal reaction buffer composed of glycine 250 mM and NaCl 3 mM, pH 6.8 and PCS less than 10%(v/v).	Glycine	193-200	alpha-N-acetylgalactosaminidase	Homo sapiens	25-56
22978602-1	2013	BACKGROUND AND PURPOSE: Concentrations of extracellular glycine in the CNS are regulated by two Na(+)/Cl(-) -dependent glycine transporters, GlyT1 and GlyT2.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	141-146
23276279-1	2013	gamma-MSH (gamma-melanocyte-stimulating hormone, H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH), with its exquisite specificity and potency, has recently created much excitement as a drug lead.	Glycine	95-101	proopiomelanocortin	Homo sapiens	0-9
23276279-1	2013	gamma-MSH (gamma-melanocyte-stimulating hormone, H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH), with its exquisite specificity and potency, has recently created much excitement as a drug lead.	Glycine	95-101	proopiomelanocortin	Homo sapiens	11-47
23224966-1	2013	GW182 is an 182 kDa protein with multiple glycine/tryptophan repeats (GW or WG) playing a central role in siRNA- and miRNA-mediated gene silencing.	Glycine	42-49	trinucleotide repeat containing adaptor 6A	Homo sapiens	0-5
23484211-2	2013	Based on these estimations, a three-dimensional model of Lys-Glu and Ala-Glu-Asp-Gly peptide interactions with DNA sites (GCAG and ATTTC) located in the promoter zones of genes encoding CD5, IL-2, MMP2, and Tram1 signal molecules.	Glycine	81-84	translocation associated membrane protein 1	Homo sapiens	207-212
24348681-8	2013	Isolated challenge of the keratinocytes with IL-1 beta as well as with glycine resulted in an upregulation of IL6 and IL8 mRNA expression and activation of NF kappa B pathway.	Glycine	71-78	interleukin 6	Homo sapiens	110-113
24348681-8	2013	Isolated challenge of the keratinocytes with IL-1 beta as well as with glycine resulted in an upregulation of IL6 and IL8 mRNA expression and activation of NF kappa B pathway.	Glycine	71-78	C-X-C motif chemokine ligand 8	Homo sapiens	118-121
24348681-8	2013	Isolated challenge of the keratinocytes with IL-1 beta as well as with glycine resulted in an upregulation of IL6 and IL8 mRNA expression and activation of NF kappa B pathway.	Glycine	71-78	nuclear factor kappa B subunit 1	Homo sapiens	156-166
23097434-1	2013	We have recently isolated a rhesus macaque cytotoxic T cell line, 2N5.1, that specifically recognizes an N-myristoylated 5-mer peptide (C(14)-Gly-Gly-Ala-Ile-Ser [C14nef5]) derived from the simian immunodeficiency virus (SIV) Nef protein.	Glycine	142-145	nef protein	Simian immunodeficiency virus	226-229
23194655-0	2013	Glycine reuptake inhibition as a new therapeutic approach in schizophrenia: focus on the glycine transporter 1 (GlyT1).	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	89-110
23194655-0	2013	Glycine reuptake inhibition as a new therapeutic approach in schizophrenia: focus on the glycine transporter 1 (GlyT1).	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	112-117
23116391-1	2013	Over the years, accumulating evidence has indicated that D-serine represents the endogenous ligand for the glycine modulatory binding site on the NR1 subunit of N-methyl-D-aspartate receptors in various brain areas.	Glycine	107-114	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	146-149
23573143-4	2013	The expression level of phosphorylated FAK, Akt, ERK1/2, and Rb was decreased p21 expression while level was increased in WEHI-3 treated with GLY.	Glycine	142-145	thymoma viral proto-oncogene 1	Mus musculus	44-47
23573143-8	2013	Accordingly, GLY demonstrated an inhibitory effect on tumor growth with a regulatory mechanism partially through inhibiting FAK, Akt, and ERK expression in WEHI-3 cells.	Glycine	13-16	thymoma viral proto-oncogene 1	Mus musculus	129-132
23573143-8	2013	Accordingly, GLY demonstrated an inhibitory effect on tumor growth with a regulatory mechanism partially through inhibiting FAK, Akt, and ERK expression in WEHI-3 cells.	Glycine	13-16	mitogen-activated protein kinase 1	Mus musculus	138-141
22836659-6	2013	In this study, Scl-Ab therapy was investigated in mice heterozygous for a typical OI-causing Gly Cys substitution in col1a1.	Glycine	93-96	collagen, type I, alpha 1	Mus musculus	117-123
23457309-4	2013	A novel missense mutation with a transversion of G to A at position 1462 in exon 12 of the DUOX2 gene that caused a replacement of glycine (G) with arginine (R) at codon 488 of the protein (c.1462G&gt;A, p.[G488R]) was identified.	Glycine	131-138	dual oxidase 2	Homo sapiens	91-96
23457309-7	2013	This p.G488R substitution occurred in a highly conserved glycine residue of the mammalian DUOX2 protein.	Glycine	57-64	dual oxidase 2	Homo sapiens	90-95
23097434-1	2013	We have recently isolated a rhesus macaque cytotoxic T cell line, 2N5.1, that specifically recognizes an N-myristoylated 5-mer peptide (C(14)-Gly-Gly-Ala-Ile-Ser [C14nef5]) derived from the simian immunodeficiency virus (SIV) Nef protein.	Glycine	146-149	nef protein	Simian immunodeficiency virus	226-229
23285494-13	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
23554862-8	2013	Sequence analyses revealed that only one amino acid exchange in the H-protein at position 540 Asp Gly (D540G) was required for functional adaptation to human CD150.	Glycine	98-101	signaling lymphocytic activation molecule family member 1	Homo sapiens	158-163
24052731-6	2012	We identified two patients with candidate mutations: m.6852G&gt;A that produces an amino acid change of glycine to serine in the MT-CO1 gene and m.8033A&gt;G (Ile Val) in the MT-CO2 gene.	Glycine	104-111	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	175-181
23093664-1	2012	OBJECTIVE: In vivo, after subcutaneous injection, insulin glargine (21(A)-Gly-31(B)-Arg-32(B)-Arg-human insulin) is enzymatically processed into 21(A)-Gly-human insulin (metabolite 1 [M1]).	Glycine	74-77	insulin	Homo sapiens	50-57
22893680-7	2012	Expression of the CaM isoform Gly-Ser-His-CaM (GSH-CaM), which has much higher binding affinity than wild-type CaM for RyR1, restored normal CaM binding to RyR2 in both SR and myocytes of failing hearts.	Glycine	30-33	ryanodine receptor 1	Canis lupus familiaris	119-123
22893680-7	2012	Expression of the CaM isoform Gly-Ser-His-CaM (GSH-CaM), which has much higher binding affinity than wild-type CaM for RyR1, restored normal CaM binding to RyR2 in both SR and myocytes of failing hearts.	Glycine	30-33	ryanodine receptor 2	Canis lupus familiaris	156-160
23093664-1	2012	OBJECTIVE: In vivo, after subcutaneous injection, insulin glargine (21(A)-Gly-31(B)-Arg-32(B)-Arg-human insulin) is enzymatically processed into 21(A)-Gly-human insulin (metabolite 1 [M1]).	Glycine	74-77	insulin	Homo sapiens	104-111
23093664-1	2012	OBJECTIVE: In vivo, after subcutaneous injection, insulin glargine (21(A)-Gly-31(B)-Arg-32(B)-Arg-human insulin) is enzymatically processed into 21(A)-Gly-human insulin (metabolite 1 [M1]).	Glycine	74-77	insulin	Homo sapiens	104-111
23093664-1	2012	OBJECTIVE: In vivo, after subcutaneous injection, insulin glargine (21(A)-Gly-31(B)-Arg-32(B)-Arg-human insulin) is enzymatically processed into 21(A)-Gly-human insulin (metabolite 1 [M1]).	Glycine	151-154	insulin	Homo sapiens	50-57
23093664-1	2012	OBJECTIVE: In vivo, after subcutaneous injection, insulin glargine (21(A)-Gly-31(B)-Arg-32(B)-Arg-human insulin) is enzymatically processed into 21(A)-Gly-human insulin (metabolite 1 [M1]).	Glycine	151-154	insulin	Homo sapiens	104-111
23093664-1	2012	OBJECTIVE: In vivo, after subcutaneous injection, insulin glargine (21(A)-Gly-31(B)-Arg-32(B)-Arg-human insulin) is enzymatically processed into 21(A)-Gly-human insulin (metabolite 1 [M1]).	Glycine	151-154	insulin	Homo sapiens	104-111
23093664-2	2012	21(A)-Gly-des-30(B)-Thr-human insulin (metabolite 2 [M2]) is also found.	Glycine	6-9	insulin	Homo sapiens	30-37
23093664-11	2012	Glargine is rapidly and nearly completely processed to M1 (21(A)-Gly-human insulin), which mediates the metabolic effect of injected glargine.	Glycine	65-68	insulin	Homo sapiens	75-82
23011956-5	2012	The primary role of these is glycine accumulation via the GLYT1 transporter, with a secondary contribution by betaine accumulation via the SIT1 transporter.	Glycine	29-36	solute carrier family 6 member 9	Homo sapiens	58-63
20401697-5	2012	Analysis of the AVP gene revealed a novel mutation G54E that changes a normal glycine to glutamic acid, caused by a guanine to adenine change at nucleotide g.1537 (exon 2) of the AVP gene.	Glycine	78-85	arginine vasopressin	Homo sapiens	16-19
20401697-5	2012	Analysis of the AVP gene revealed a novel mutation G54E that changes a normal glycine to glutamic acid, caused by a guanine to adenine change at nucleotide g.1537 (exon 2) of the AVP gene.	Glycine	78-85	arginine vasopressin	Homo sapiens	179-182
23233222-5	2012	We found that the peak current of NMDARs and Ca(2+) influx induced by high concentration of NMDA were reduced by treatment of glycine (0.03-10 mumol L(-1)) in a dose-dependent manner, and that the glycine-dependent inhibition of NMDAR responses, which were induced at 300 mumol L(-1) NMDA, was reversed by ZnCl(2) through the blocking of the NR2A subunit of NMDARs, but was less influenced by ifenprodil, a NR2B inhibitor.	Glycine	126-133	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	342-346
23233222-5	2012	We found that the peak current of NMDARs and Ca(2+) influx induced by high concentration of NMDA were reduced by treatment of glycine (0.03-10 mumol L(-1)) in a dose-dependent manner, and that the glycine-dependent inhibition of NMDAR responses, which were induced at 300 mumol L(-1) NMDA, was reversed by ZnCl(2) through the blocking of the NR2A subunit of NMDARs, but was less influenced by ifenprodil, a NR2B inhibitor.	Glycine	197-204	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	342-346
23233222-6	2012	Our results suggest that the glycine-dependent inactivation of NMDARs is potentially modulated by the regulatory subunit NR2A.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	121-125
23060441-2	2012	RESULTS: Comprehensive mapping of alpha1(V) post-translational modifications reveals unexpectedly large numbers of X-position hydroxyprolines in Gly-X-Y amino acid triplets.	Glycine	145-148	collagen type V alpha 1 chain	Homo sapiens	34-43
22981378-4	2012	Indeed, inhibition of ATP7 expression by RNAi led to a decrease in mature amidated neuropeptides and the appearance of C-terminally Gly-extended neuropeptides.	Glycine	132-135	ATP7	Drosophila melanogaster	22-26
23148652-4	2012	Analogues 3 and 7, where glycine at positions 2 and 6 of the parent compound was replaced by Ala, exhibited enhanced cytotoxicity against KB (3, IC50 6.3 muM; 7, IC50 7.8 muM) and MDA-MB-231 breast cancer cells (3, IC50 10.2 muM; 7, IC50 7.7 muM), thereby suggesting possible selective targeting of these cancer cells by these peptides.	Glycine	25-32	latexin	Homo sapiens	154-157
22842481-5	2012	VPY transport and anti-inflammatory activity in Caco-2 cells was reduced in the presence of Gly-Sar, indicating this activity was mediated by PepT1.	Glycine	92-95	solute carrier family 15 member 1	Homo sapiens	142-147
22989262-6	2012	RESULTS: The frequency of TAP1-637-Gly (allele G) was significantly higher in persistently HBV-infected individuals (CHB and LC) than that of SR subjects (OR = 1.58, 95% CI 1.12-2.45, p = 0.024; OR = 1.78, 95% CI 1.27-2.68, p = 0.002) by a logistic regression analysis.	Glycine	35-38	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	26-30
23200065-6	2012	First are inhibitors for a transporter for glycine termed GlyT1.	Glycine	43-50	solute carrier family 6 member 9	Homo sapiens	58-63
23200065-8	2012	Inhibiting GlyT1 increases glycine levels and can selectively increase NMDA receptor signaling.	Glycine	27-34	solute carrier family 6 member 9	Homo sapiens	11-16
22829651-1	2012	Myristoyl-CoA (CoA):protein N-myristoyltransferase (NMT) catalyzes protein modification through covalent attachment of a C14 fatty acid (myristic acid) to the N-terminal glycine of proteins, thus promoting protein-protein and protein-membrane interactions.	Glycine	170-177	N-myristoyltransferase 1	Homo sapiens	28-50
22829651-1	2012	Myristoyl-CoA (CoA):protein N-myristoyltransferase (NMT) catalyzes protein modification through covalent attachment of a C14 fatty acid (myristic acid) to the N-terminal glycine of proteins, thus promoting protein-protein and protein-membrane interactions.	Glycine	170-177	N-myristoyltransferase 1	Homo sapiens	52-55
23061476-0	2012	Tunneling lifetime of the ttc/VIp conformer of glycine in low-temperature matrices.	Glycine	47-54	vasoactive intestinal peptide	Homo sapiens	30-33
23061476-1	2012	Conformer ttc/VIp of glycine and glycine-N,N,O-d(3) has been prepared in low-temperature Ar, Kr, Xe, and N(2) matrices by near-infrared (NIR) laser irradiation of the first OH stretching overtone of conformer ttt/Ip.	Glycine	21-28	vasoactive intestinal peptide	Homo sapiens	14-17
23061476-1	2012	Conformer ttc/VIp of glycine and glycine-N,N,O-d(3) has been prepared in low-temperature Ar, Kr, Xe, and N(2) matrices by near-infrared (NIR) laser irradiation of the first OH stretching overtone of conformer ttt/Ip.	Glycine	33-40	vasoactive intestinal peptide	Homo sapiens	14-17
23061476-2	2012	Glycine (and glycine-N,N,O-d(3)) ttc/VIp was found to convert back to ttt/Ip in the dark by hydrogen-atom tunneling.	Glycine	0-7	vasoactive intestinal peptide	Homo sapiens	37-40
23061476-2	2012	Glycine (and glycine-N,N,O-d(3)) ttc/VIp was found to convert back to ttt/Ip in the dark by hydrogen-atom tunneling.	Glycine	13-20	vasoactive intestinal peptide	Homo sapiens	37-40
23061476-4	2012	In correspondence with the observation for the cis-to-trans conversion of formic and acetic acid, the tunneling half-life of glycine ttc/VIp in a N(2) matrix is more than 3 orders of magnitude longer (6.69 x 10(3) and 1.38 x 10(4) s for two different sites) than in noble gas matrices due to complex formation with the host molecules.	Glycine	125-132	vasoactive intestinal peptide	Homo sapiens	137-140
22407957-0	2012	Lactate and glycine-potential MR biomarkers of prognosis in estrogen receptor-positive breast cancers.	Glycine	12-19	estrogen receptor 1	Homo sapiens	60-77
23115806-4	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
22464987-2	2012	For this purpose disulfide stabilized scFv domains of the EGFR/ADCC antibody GA201 were fused via serine-glycine connectors to the C-terminus of the heavy (XGFR2) or light chain (XGFR4), or the N-termini of the light (XGFR5) or heavy chain (XGFR3) of the IGF-1R antibody R1507 as parental IgG1 antibody.	Glycine	105-112	epidermal growth factor receptor	Homo sapiens	58-62
22790597-8	2012	Furthermore, plasma and muscle levels of glycine and L-tryptophan were significantly decreased in ace2 null mice, with other neutral amino acids displaying a similar trend.	Glycine	41-48	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	98-102
22814002-5	2012	Pharmacology revealed a triheteromeric-receptor with features common to glutamate-activated GluN1/GluN2-containing and glycine-activated GluN1/GluN3-containing diheteromeric NMDARs.	Glycine	119-126	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	137-142
22796215-4	2012	The protective effect of glycine was associated with reduction of terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) positive cells, deactivation of phosphor-JNK, inhibition of caspase-3 cleavage, down-regulation of FasL/Fas, and up-regulation of bcl-2 and bcl-2/bax in the mouse I/R penumbra.	Glycine	25-32	B cell leukemia/lymphoma 2	Mus musculus	272-277
22796215-4	2012	The protective effect of glycine was associated with reduction of terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) positive cells, deactivation of phosphor-JNK, inhibition of caspase-3 cleavage, down-regulation of FasL/Fas, and up-regulation of bcl-2 and bcl-2/bax in the mouse I/R penumbra.	Glycine	25-32	B cell leukemia/lymphoma 2	Mus musculus	282-287
22897496-0	2012	Targeting the hinge glycine flip and the activation loop: novel approach to potent p38alpha inhibitors.	Glycine	20-27	mitogen-activated protein kinase 14	Homo sapiens	83-91
22779445-7	2012	In turn, NP-647 also inhibits the uptake of Gly-Sar into Caco-2 cells and, together, this evidence suggests that PEPT1 is involved in the process.	Glycine	44-47	solute carrier family 15 member 1	Homo sapiens	113-118
22424122-5	2012	Results showed that a novel heterozygous in-frame insertion/deletion (indel), c.1158_1159delAT; c.1158_1159insCACCAACC, was identified in a highly conserved region encoding the glycine-rich area of TDP-43 in a patient with FAV.	Glycine	177-184	TAR DNA binding protein	Homo sapiens	198-204
22829593-0	2012	The in vivo role of androgen receptor SUMOylation as revealed by androgen insensitivity syndrome and prostate cancer mutations targeting the proline/glycine residues of synergy control motifs.	Glycine	149-156	androgen receptor	Homo sapiens	20-37
22812023-5	2004	In terms of agonist requirement and channel operation, the three subunit families exhibit distinct properties; NR1 and NR3 require glycine as the agonist and have no binding site for glutamate, whereas NR2 is activated by glutamate.	Glycine	131-138	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	111-114
23336232-5	2012	There was 1 nucleotide differed from the closest matching HLA-A*11:01:01 at position 393(G A), which resulting a change from GGG to GGA at codon 107, led to a silent mutation, conserving the amino acid Gly.	Glycine	202-205	major histocompatibility complex, class I, A	Homo sapiens	58-63
22920190-5	2012	The inhibition by non-cytoxic doses of GLY of VSMCs migration was through its negative regulatory effects on phosphorylated ERK1/2, PI3K/AKT, and FAK.	Glycine	39-42	AKT serine/threonine kinase 1	Rattus norvegicus	137-140
22791362-2	2012	The growth chart is based on longitudinal height measurements of 79 patients with glycine substitutions in the triple-helical domain of COL2A1.	Glycine	82-89	collagen type II alpha 1 chain	Homo sapiens	136-142
22973545-5	2012	The susceptible type of FEZL with a glycine stretch containing 13 glycines (13G) and the longer C stretch of IGF1R together enhanced expression of IGF1R.	Glycine	36-43	insulin like growth factor 1 receptor	Bos taurus	147-152
22915106-0	2012	PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.	Glycine	84-91	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	48-53
22915106-6	2012	Here, we show that endogenous GluA1 is rapidly inserted at the synaptic plasma membrane of rat hippocampal neurons immediately after stimulation with elevated glycine, a treatment known to induce LTP.	Glycine	159-166	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	30-35
22915106-7	2012	In contrast, GluA2 is restricted from trafficking to the cell surface by a glycine-induced increase in PICK1-GluA2 binding on endosomal compartments.	Glycine	75-82	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	13-18
22915106-7	2012	In contrast, GluA2 is restricted from trafficking to the cell surface by a glycine-induced increase in PICK1-GluA2 binding on endosomal compartments.	Glycine	75-82	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	109-114
22732655-0	2012	Glycine suppresses TNF-alpha-induced activation of NF-kappaB in differentiated 3T3-L1 adipocytes.	Glycine	0-7	tumor necrosis factor	Mus musculus	19-28
22732655-0	2012	Glycine suppresses TNF-alpha-induced activation of NF-kappaB in differentiated 3T3-L1 adipocytes.	Glycine	0-7	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	51-60
22732655-6	2012	(2011 and 2012) recently reported a glycine-dependent reduction in NF-kappaB levels.	Glycine	36-43	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	67-76
22732655-7	2012	Here, we have investigated the role of glycine in the regulation of NF-kappaB in differentiated 3T3-L1 adipocytes.	Glycine	39-46	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	68-77
22732655-8	2012	The results revealed that pretreatment with glycine interfered with the activation of NF-kappaB, which has been shown to be stimulated by tumor necrosis factor-alpha (TNF-alpha).	Glycine	44-51	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	86-95
22732655-8	2012	The results revealed that pretreatment with glycine interfered with the activation of NF-kappaB, which has been shown to be stimulated by tumor necrosis factor-alpha (TNF-alpha).	Glycine	44-51	tumor necrosis factor	Mus musculus	138-165
22732655-8	2012	The results revealed that pretreatment with glycine interfered with the activation of NF-kappaB, which has been shown to be stimulated by tumor necrosis factor-alpha (TNF-alpha).	Glycine	44-51	tumor necrosis factor	Mus musculus	167-176
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	0-7	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	25-34
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	0-7	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	189-202
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	0-7	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	215-224
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	0-7	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	248-251
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	316-323	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	25-34
22715100-5	2012	In single-substitution mutants, we found that a position in both subunits adjacent to one previously identified, GluN1(Gly-638) and GluN2A(Phe-636), can strongly regulate ethanol sensitivity.	Glycine	119-122	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	113-118
22715100-6	2012	Significant interactions affecting ethanol inhibition and receptor deactivation were observed at four pairs of positions in GluN1/GluN2A: Gly-638/Met-823, Phe-639/Leu-824, Met-818/Phe-636, and Leu-819/Phe-637; the latter pair also interacted with respect to desensitization.	Glycine	138-141	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	124-129
22715100-6	2012	Significant interactions affecting ethanol inhibition and receptor deactivation were observed at four pairs of positions in GluN1/GluN2A: Gly-638/Met-823, Phe-639/Leu-824, Met-818/Phe-636, and Leu-819/Phe-637; the latter pair also interacted with respect to desensitization.	Glycine	138-141	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	130-136
22812023-6	2004	Opening of the ion channel is dependent on the voltage state of the cell membrane as well as the binding of dual ligands; glutamate binds to a site on the NR2 subunit, and glycine or d-serine binds to a modulatory site on the NR1 subunit (2, 4).	Glycine	172-179	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	226-229
22634870-8	2012	CONCLUSIONS: These findings confirm xenon binds to the glycine site of the GluN1 subunit of the NMDA receptor and indicate that interactions between xenon and the aromatic ring of the phenylalanine 758 residue are important for xenon binding.	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	75-80
22490677-7	2012	This correspondence is demonstrated by binding of integrin alpha(IIb)beta(3) to the fourth module seen in EM, VWC4, which bears the VWF Arg-Gly-Asp motif.	Glycine	140-143	von Willebrand factor	Homo sapiens	132-135
22612268-1	2012	Well-ordered water molecules are displaced from thrombin"s hydrophobic S3/4-pocket by P3-varied ligands (Gly, d-Ala, d-Val, d-Leu to d-Cha with increased hydrophobicity and steric requirement).	Glycine	105-108	coagulation factor II, thrombin	Homo sapiens	48-56
22463587-1	2012	N-myristoyltransferase (NMT) is an essential eukaryotic enzyme which catalyzes the transfer of the myristoyl group to the terminal glycine residue of a number of proteins including those involved in signal transduction and apoptotic pathways.	Glycine	131-138	N-myristoyltransferase 1	Homo sapiens	0-22
22539596-3	2012	Cadherin 6 is expressed on the platelet surface and contains an arginine-glycine-aspartic acid motif, suggesting that it might have a supportive role in thrombus formation.	Glycine	73-80	cadherin 6	Mus musculus	0-10
22539596-6	2012	Platelet adhesion to immobilized cadherin 6 was inhibited by arginine-glycine-aspartic acid-serine tetrapeptides.	Glycine	70-77	cadherin 6	Mus musculus	33-43
22463587-1	2012	N-myristoyltransferase (NMT) is an essential eukaryotic enzyme which catalyzes the transfer of the myristoyl group to the terminal glycine residue of a number of proteins including those involved in signal transduction and apoptotic pathways.	Glycine	131-138	N-myristoyltransferase 1	Homo sapiens	24-27
22576375-1	2012	Crystal specimens of the gamma-polymorph of achiral glycine which crystallize in space groups P31 and P32 as determined by the anomalous X-ray scattering method are shown to be laevorotatory and dextrorotatory, respectively, as determined by optical rotation of the crystals.	Glycine	52-59	ATPase H+ transporting V1 subunit E1	Homo sapiens	94-97
22454518-6	2012	Switching the number of glycines in the PH domains of cytohesin 2 and cytohesin 3 is sufficient to reverse their effects on adhesion and spreading and to reverse their subcellular locations.	Glycine	24-32	cytohesin 2	Homo sapiens	54-65
22454518-6	2012	Switching the number of glycines in the PH domains of cytohesin 2 and cytohesin 3 is sufficient to reverse their effects on adhesion and spreading and to reverse their subcellular locations.	Glycine	24-32	cytohesin 3	Homo sapiens	70-81
22454518-7	2012	Importantly, we also find that a mutant form of cytohesin 3/GRP1 that has three rather than two glycines in its PH domain rescues beta1 integrin recycling in cytohesin 2/ARNO knockdown cells.	Glycine	96-104	cytohesin 3	Homo sapiens	48-59
22454518-7	2012	Importantly, we also find that a mutant form of cytohesin 3/GRP1 that has three rather than two glycines in its PH domain rescues beta1 integrin recycling in cytohesin 2/ARNO knockdown cells.	Glycine	96-104	cytohesin 3	Homo sapiens	60-64
22454518-8	2012	Conversely, a mutant form of cytohesin 2/ARNO with two glycines in its PH domain fails to rescue beta1 integrin recycling.	Glycine	55-63	cytohesin 2	Homo sapiens	29-40
22454518-8	2012	Conversely, a mutant form of cytohesin 2/ARNO with two glycines in its PH domain fails to rescue beta1 integrin recycling.	Glycine	55-63	cytohesin 2	Homo sapiens	41-45
22563080-5	2012	For FUS, the arginine-glycine-glycine zinc finger domain, which is the protein"s main RNA binding domain, is most important for SG recruitment, whereas the glycine-rich domain and RNA recognition motif (RRM) domain have a minor contribution and the glutamine-rich domain is dispensable.	Glycine	22-29	FUS RNA binding protein	Homo sapiens	4-7
22563080-5	2012	For FUS, the arginine-glycine-glycine zinc finger domain, which is the protein"s main RNA binding domain, is most important for SG recruitment, whereas the glycine-rich domain and RNA recognition motif (RRM) domain have a minor contribution and the glutamine-rich domain is dispensable.	Glycine	30-37	FUS RNA binding protein	Homo sapiens	4-7
22563080-6	2012	For TDP-43, both the RRM1 and the C-terminal glycine-rich domain are required for SG localization.	Glycine	45-52	TAR DNA binding protein	Homo sapiens	4-10
22563080-7	2012	ALS-associated point mutations located in the glycine-rich domain of TDP-43 do not affect SG recruitment.	Glycine	46-53	TAR DNA binding protein	Homo sapiens	69-75
22450660-5	2012	However, glycine and glutamate are more effective at preventing copper-mediated DNA damage (IC(50) values of 35 and 12.9 muM, respectively) than L-DOPA, the only catecholamine to prevent this damage (IC(50) = 73 muM).	Glycine	9-16	latexin	Homo sapiens	121-124
22450660-5	2012	However, glycine and glutamate are more effective at preventing copper-mediated DNA damage (IC(50) values of 35 and 12.9 muM, respectively) than L-DOPA, the only catecholamine to prevent this damage (IC(50) = 73 muM).	Glycine	9-16	latexin	Homo sapiens	212-215
22526622-4	2012	Accordingly, this Ecrg4 is resistant to washing cells with neutral, high salt (2 M NaCl), acidic (50 mM glycine, pH 2.8), or basic (100 mM Na(2)CO(3), pH 11) buffers.	Glycine	104-111	ECRG4 augurin precursor	Homo sapiens	18-23
22905486-1	2012	The main purpose of this study was to evaluate the targeting effect of cyclic arginine-glycine-aspartic peptide (cRGD)-modified monomethoxy (polyethylene glycol)-poly (D, L-lactide-co-glycolide)-poly (L-lysine) nanoparticles (mPEG-PLGA-PLL-cRGD NPs) for gastric cancer SGC-7901 cells.	Glycine	87-94	sarcoglycan beta	Homo sapiens	269-272
22675745-3	2004	Glycine metabolism is controlled by GlyT1 and glycine transporter 2 (GlyT2) (2).	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	36-41
22402478-1	2012	Single crystals of potassium acid phthalate (KAP) have been grown from aqueous solution by slow evaporation technique by adding l-alanine (LA), glycine (Gly) and l-tyrosine (LT) as additives.	Glycine	144-151	napsin A aspartic peptidase	Homo sapiens	45-48
22402478-1	2012	Single crystals of potassium acid phthalate (KAP) have been grown from aqueous solution by slow evaporation technique by adding l-alanine (LA), glycine (Gly) and l-tyrosine (LT) as additives.	Glycine	153-156	napsin A aspartic peptidase	Homo sapiens	45-48
22675745-7	2004	In this process, GlyT1 is considered to play an important role by regulating glycine concentration (5, 7, 8).	Glycine	77-84	solute carrier family 6 member 9	Homo sapiens	17-22
22675745-8	2004	Because of these findings, pharmacological manipulation of glycine-mediated neurotransmission with GlyT1 inhibitors has become an active field for the development of novel treatments for neuropsychiatric disorders, and evidence has demonstrated the beneficial effect of the inhibitors on the negative and cognitive symptoms of schizophrenia (3, 9).	Glycine	59-66	solute carrier family 6 member 9	Homo sapiens	99-104
22649803-19	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
22649804-19	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
22654457-1	2012	AIM: To investigate the effects and mechanisms of action of glycine on phagocytosis and tumor necrosis factor (TNF)-alpha secretion by Kupffer cells in vitro.	Glycine	60-67	tumor necrosis factor	Rattus norvegicus	88-121
22553026-4	2012	Here, we show the mechanism of action for 3-chloro-4-fluoro-N-[(4-[(2-(phenylcarbonyl)hydrazino)carbonyl]phenyl)methyl]-benzenesulfonamide (TCN-201), a new GluN1/GluN2A-selective NMDA receptor antagonist whose inhibition can be surmounted by glycine.	Glycine	242-249	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	162-168
22408254-0	2012	Reversible lysine acetylation regulates activity of human glycine N-acyltransferase-like 2 (hGLYATL2): implications for production of glycine-conjugated signaling molecules.	Glycine	58-65	glycine-N-acyltransferase like 2	Homo sapiens	92-100
22539580-8	2012	The type of mutation influenced survival (p < 0.0001), and the G298S1, lying in the TARDBP super rich glycine-residue domain, was associated with the worst survival (27 months).	Glycine	102-109	TAR DNA binding protein	Homo sapiens	84-90
22408254-9	2012	The hGLYATL2 enzyme conjugates medium- and long-chain saturated and unsaturated acyl-CoA esters to glycine, resulting in the production of N-oleoyl glycine and also N-arachidonoyl glycine.	Glycine	99-106	glycine-N-acyltransferase like 2	Homo sapiens	4-12
22593943-0	2004	2-chloro-N-((S)-((S)-1-[(11)C]methylpiperidine-2-yl)(thiophen-3-yl)methyl)-3-(trifluoromethyl)benzamide ([(11)C]SA1) and derivatives The amino acid (aa) glycine acts as a neurotransmitter in the mammalian central nervous system (CNS) and modulates the neuroexcitatory activity of the N-methyl-d-aspartate (NMDA) receptor (NMDAR) through strychnine-insensitive glycine binding sites located on the receptor (for details regarding structure and function of NMDAR, see Paoletti et al.	Glycine	153-160	stromal antigen 1	Homo sapiens	112-115
22593943-0	2004	2-chloro-N-((S)-((S)-1-[(11)C]methylpiperidine-2-yl)(thiophen-3-yl)methyl)-3-(trifluoromethyl)benzamide ([(11)C]SA1) and derivatives The amino acid (aa) glycine acts as a neurotransmitter in the mammalian central nervous system (CNS) and modulates the neuroexcitatory activity of the N-methyl-d-aspartate (NMDA) receptor (NMDAR) through strychnine-insensitive glycine binding sites located on the receptor (for details regarding structure and function of NMDAR, see Paoletti et al.	Glycine	360-367	stromal antigen 1	Homo sapiens	112-115
22593943-6	2004	However, rapid sequestration into the nerve terminals and surrounding glial cells by two high-affinity transporters, designated as GlyT-1 and GlyT-2, block the activity of glycine on the NMDAR in the synapse (4).	Glycine	172-179	solute carrier family 6 member 9	Homo sapiens	131-137
22593943-7	2004	GlyT-1 has been shown to maintain low levels of glycine at the synapse, which indicates that the aa participates in controlling the process of neurotransmission through the NMDAR (4).	Glycine	48-55	solute carrier family 6 member 9	Homo sapiens	0-6
22593943-8	2004	It has been hypothesized that inhibition of GlyT-1 would increase glycine concentrations around the synapse (because by inhibiting the GlyT-1 transporter glycine will not be sequestered into the surrounding glial cells), which would enhance the activity of the NMDAR.	Glycine	66-73	solute carrier family 6 member 9	Homo sapiens	44-50
22593943-8	2004	It has been hypothesized that inhibition of GlyT-1 would increase glycine concentrations around the synapse (because by inhibiting the GlyT-1 transporter glycine will not be sequestered into the surrounding glial cells), which would enhance the activity of the NMDAR.	Glycine	154-161	solute carrier family 6 member 9	Homo sapiens	44-50
22593943-8	2004	It has been hypothesized that inhibition of GlyT-1 would increase glycine concentrations around the synapse (because by inhibiting the GlyT-1 transporter glycine will not be sequestered into the surrounding glial cells), which would enhance the activity of the NMDAR.	Glycine	154-161	solute carrier family 6 member 9	Homo sapiens	135-141
21537880-11	2012	Tau, but not Cys, Gly and Met, inhibited, by as much as 70%, insulin-mediated H2O2 pool increase.	Glycine	18-21	insulin	Homo sapiens	61-68
21373768-9	2012	Glycine treatment suppressed these apoptotic events, signifying its protective role in Hg-induced hepatocyte apoptosis as referred by reduction of p38, JNK and ERK MAPK signaling pathways.	Glycine	0-7	mitogen-activated protein kinase 1	Mus musculus	164-168
21373768-9	2012	Glycine treatment suppressed these apoptotic events, signifying its protective role in Hg-induced hepatocyte apoptosis as referred by reduction of p38, JNK and ERK MAPK signaling pathways.	Glycine	0-7	mitogen-activated protein kinase 1	Mus musculus	160-163
22421509-4	2012	The PC1KO mouse presented a decrease in five proTRH-derived peptides, whereas the PC2KO mouse showed only lesser reduction in three TRH (Gln-His-Pro), TRH-Gly (Gln-His-Pro-Gly), and the short forms preproTRH(178-184) (pFQ(7)) and preproTRH(186-199) (pSE(14)) of pFE(22) (preproTRH(178-199)).	Glycine	155-158	proprotein convertase subtilisin/kexin type 2	Mus musculus	82-85
22416082-2	2012	To gain better insight into this process, a degradation-resistant GLP-2 analog, human (Gly(2))GLP-2(1-33) [h(Gly(2))GLP-2] was intracerebroventricularly injected into mice to examine its action on food and water intake and also activation of hypothalamic anorexigenic alpha-melanocyte-stimulating hormone/proopiomelanocortin, neurotensin, and orexigenic neuropeptide Y, and ghrelin neurons.	Glycine	87-90	glucagon	Homo sapiens	66-71
22416082-2	2012	To gain better insight into this process, a degradation-resistant GLP-2 analog, human (Gly(2))GLP-2(1-33) [h(Gly(2))GLP-2] was intracerebroventricularly injected into mice to examine its action on food and water intake and also activation of hypothalamic anorexigenic alpha-melanocyte-stimulating hormone/proopiomelanocortin, neurotensin, and orexigenic neuropeptide Y, and ghrelin neurons.	Glycine	87-90	glucagon	Homo sapiens	94-99
22416082-2	2012	To gain better insight into this process, a degradation-resistant GLP-2 analog, human (Gly(2))GLP-2(1-33) [h(Gly(2))GLP-2] was intracerebroventricularly injected into mice to examine its action on food and water intake and also activation of hypothalamic anorexigenic alpha-melanocyte-stimulating hormone/proopiomelanocortin, neurotensin, and orexigenic neuropeptide Y, and ghrelin neurons.	Glycine	87-90	glucagon	Homo sapiens	94-99
22530904-8	2012	NMDA/glycine mediated N-methyl-D-aspartate receptor (NMDAR) calcium influx inhibition was evaluated at a 100 muM concentration using a fluorescent calcium flux assay.	Glycine	5-12	latexin	Homo sapiens	109-112
22530913-6	2012	Docking study revealed the important amino acid residues (His 15, Tyr 59, Tyr 151, Gly 121 and Gly 122) in the active site of TNFalpha that are involved in binding of the active ligand.	Glycine	83-86	tumor necrosis factor	Homo sapiens	126-134
22530913-6	2012	Docking study revealed the important amino acid residues (His 15, Tyr 59, Tyr 151, Gly 121 and Gly 122) in the active site of TNFalpha that are involved in binding of the active ligand.	Glycine	95-98	tumor necrosis factor	Homo sapiens	126-134
22416082-2	2012	To gain better insight into this process, a degradation-resistant GLP-2 analog, human (Gly(2))GLP-2(1-33) [h(Gly(2))GLP-2] was intracerebroventricularly injected into mice to examine its action on food and water intake and also activation of hypothalamic anorexigenic alpha-melanocyte-stimulating hormone/proopiomelanocortin, neurotensin, and orexigenic neuropeptide Y, and ghrelin neurons.	Glycine	109-112	glucagon	Homo sapiens	66-71
22416082-3	2012	Central h(Gly(2))GLP-2 administration significantly suppressed food and water intake with acute weight loss at 2 h. Further, central h(Gly(2))GLP-2 robustly induced c-Fos activation in the hypothalamic arcuate, dorsomedial, ventromedial, paraventricular, and the lateral hypothalamic nuclei.	Glycine	10-13	glucagon	Homo sapiens	17-22
22416082-3	2012	Central h(Gly(2))GLP-2 administration significantly suppressed food and water intake with acute weight loss at 2 h. Further, central h(Gly(2))GLP-2 robustly induced c-Fos activation in the hypothalamic arcuate, dorsomedial, ventromedial, paraventricular, and the lateral hypothalamic nuclei.	Glycine	10-13	glucagon	Homo sapiens	142-147
22416082-3	2012	Central h(Gly(2))GLP-2 administration significantly suppressed food and water intake with acute weight loss at 2 h. Further, central h(Gly(2))GLP-2 robustly induced c-Fos activation in the hypothalamic arcuate, dorsomedial, ventromedial, paraventricular, and the lateral hypothalamic nuclei.	Glycine	135-138	glucagon	Homo sapiens	17-22
22416082-3	2012	Central h(Gly(2))GLP-2 administration significantly suppressed food and water intake with acute weight loss at 2 h. Further, central h(Gly(2))GLP-2 robustly induced c-Fos activation in the hypothalamic arcuate, dorsomedial, ventromedial, paraventricular, and the lateral hypothalamic nuclei.	Glycine	135-138	glucagon	Homo sapiens	142-147
22416082-6	2012	Treatment with h(Gly(2))GLP-2 stimulated c-Fos expression and phosphorylation of cAMP response element-binding protein/activating transcription factor-1.	Glycine	17-20	glucagon	Homo sapiens	24-29
22416082-7	2012	In addition, treatment with h(Gly(2))GLP-2 significantly increased neurotensin and ghrelin mRNA transcript levels by 50 and 95%, respectively, at 24 h after treatment in protein kinase A-dependent manner.	Glycine	30-33	glucagon	Homo sapiens	37-42
22416082-7	2012	In addition, treatment with h(Gly(2))GLP-2 significantly increased neurotensin and ghrelin mRNA transcript levels by 50 and 95%, respectively, at 24 h after treatment in protein kinase A-dependent manner.	Glycine	30-33	neurotensin	Homo sapiens	67-78
22378024-2	2012	The bovine serum albumin (BSA)-modified 13.3-nm Au nanoparticle (BSA-Au NP) probe was designed to detect Cu(2+) ions using lead ions (Pb(2+)) and 2-mercaptoethanol (2-ME) as leaching agents in a glycine-NaOH (pH 12.0) solution.	Glycine	195-202	albumin	Homo sapiens	11-24
22362770-6	2012	Alanine substitutions at positions Pro-113 Thr-115, Gly-117, Glu-122, and also Gln-109 enhanced the EphA2 receptor down-regulation and decreased p-ERK and p-AKT.	Glycine	52-55	AKT serine/threonine kinase 1	Homo sapiens	157-160
21909137-8	2012	Thus, although a full length of rictor is required to interact with its binding partner Sin1, a single amino acid of rictor Gly-934 controls its interaction with Sin1 and assembly of mTORC2.	Glycine	124-127	MAPK associated protein 1	Homo sapiens	162-166
21909137-8	2012	Thus, although a full length of rictor is required to interact with its binding partner Sin1, a single amino acid of rictor Gly-934 controls its interaction with Sin1 and assembly of mTORC2.	Glycine	124-127	MAPK associated protein 1	Homo sapiens	88-92
21909137-6	2012	A substitution of the rictor Gly-934 residue to a charged amino acid prevents formation of the rictor/Sin1 heterodimer.	Glycine	29-32	MAPK associated protein 1	Homo sapiens	102-106
22457887-4	2004	Because the integrin alphavbeta3 binds with extracellular matrix proteins (e.g., vitronectin, fibronectin) through the exposed Arg-Gly-Asp tripeptide sequence, RGD-containing peptides have been intensively studied in the past decade as a vector for imaging alphavbeta3 expression (3, 4).	Glycine	131-134	fibronectin 1	Homo sapiens	94-105
22529837-13	2012	However, we observed a glycine-induced increase in the neuropeptides arginine vasopressin and vasoactive intestinal polypeptide in the light period.	Glycine	23-30	arginine vasopressin	Homo sapiens	78-89
22536614-6	2004	However, rapid sequestration into the nerve terminals and surrounding glial cells by two high-affinity transporters, designated as GlyT-1 and GlyT-2, block the activity of glycine on the NMDAR in the synapse (3).	Glycine	172-179	solute carrier family 6 member 9	Homo sapiens	131-137
22536614-7	2004	GlyT-1 has been shown to maintain low levels of glycine at the synapse, which indicates that the aa controls neurotransmission through the NMDAR (3).	Glycine	48-55	solute carrier family 6 member 9	Homo sapiens	0-6
22536614-8	2004	It has been hypothesized that inhibition of GlyT-1 would increase glycine concentrations around the synapse, which would enhance the activity of the NMDAR.	Glycine	66-73	solute carrier family 6 member 9	Homo sapiens	44-50
22278846-2	2012	The tip was modified with an antibody sensitive to the exposure of the arginine-glycine-aspartic acid (RGD) groups in FN.	Glycine	80-87	fibronectin 1	Homo sapiens	118-120
22369721-4	2012	HeLa-hPEPT1/hPEPT2 cells were selected by measuring the protein expression and the uptake activities of JBP485 and Gly-Sar.	Glycine	115-118	solute carrier family 15 member 2	Homo sapiens	12-18
22369721-6	2012	The Michaelis-Menten constant (K(m)) values of Gly-Sar uptake by the hPEPT1 and hPEPT2-expressing transfectants were 1.03 mM and 0.0965 mM, respectively, and the K(m) values of JBP485 uptake were 1.33 mM for PEPT1 and 0.144 mM for PEPT2.	Glycine	47-50	solute carrier family 15 member 1	Homo sapiens	69-75
22369721-6	2012	The Michaelis-Menten constant (K(m)) values of Gly-Sar uptake by the hPEPT1 and hPEPT2-expressing transfectants were 1.03 mM and 0.0965 mM, respectively, and the K(m) values of JBP485 uptake were 1.33 mM for PEPT1 and 0.144 mM for PEPT2.	Glycine	47-50	solute carrier family 15 member 2	Homo sapiens	80-86
22369721-6	2012	The Michaelis-Menten constant (K(m)) values of Gly-Sar uptake by the hPEPT1 and hPEPT2-expressing transfectants were 1.03 mM and 0.0965 mM, respectively, and the K(m) values of JBP485 uptake were 1.33 mM for PEPT1 and 0.144 mM for PEPT2.	Glycine	47-50	solute carrier family 15 member 1	Homo sapiens	70-75
22369721-6	2012	The Michaelis-Menten constant (K(m)) values of Gly-Sar uptake by the hPEPT1 and hPEPT2-expressing transfectants were 1.03 mM and 0.0965 mM, respectively, and the K(m) values of JBP485 uptake were 1.33 mM for PEPT1 and 0.144 mM for PEPT2.	Glycine	47-50	solute carrier family 15 member 2	Homo sapiens	81-86
22369721-8	2012	Maximal uptake of Gly-Sar were detected at pH 5.8 (for PEPT1) and pH 6.5 (for PEPT2), suggesting that both HeLa-hPEPT1 and HeLa-hPEPT2 were H(+) dependent transporters.	Glycine	18-21	solute carrier family 15 member 1	Homo sapiens	55-60
22369721-8	2012	Maximal uptake of Gly-Sar were detected at pH 5.8 (for PEPT1) and pH 6.5 (for PEPT2), suggesting that both HeLa-hPEPT1 and HeLa-hPEPT2 were H(+) dependent transporters.	Glycine	18-21	solute carrier family 15 member 2	Homo sapiens	78-83
22369721-8	2012	Maximal uptake of Gly-Sar were detected at pH 5.8 (for PEPT1) and pH 6.5 (for PEPT2), suggesting that both HeLa-hPEPT1 and HeLa-hPEPT2 were H(+) dependent transporters.	Glycine	18-21	solute carrier family 15 member 1	Homo sapiens	112-118
22369721-8	2012	Maximal uptake of Gly-Sar were detected at pH 5.8 (for PEPT1) and pH 6.5 (for PEPT2), suggesting that both HeLa-hPEPT1 and HeLa-hPEPT2 were H(+) dependent transporters.	Glycine	18-21	solute carrier family 15 member 2	Homo sapiens	128-134
22369721-9	2012	Stably transfected HeLa-hPEPT1/HeLa-hPEPT2 cells were constructed successfully, and the functions of hPEPT1/hPEPT2 were identified using their substrates, JBP485 and Gly-Sar.	Glycine	166-169	solute carrier family 15 member 1	Homo sapiens	101-107
22369721-9	2012	Stably transfected HeLa-hPEPT1/HeLa-hPEPT2 cells were constructed successfully, and the functions of hPEPT1/hPEPT2 were identified using their substrates, JBP485 and Gly-Sar.	Glycine	166-169	solute carrier family 15 member 2	Homo sapiens	108-114
23961177-9	2012	Moreover, essential amino acids (Val, Phe and His) and the non-essential amino acids (Gly and Ser) content was significantly higher in cow milk beta-casein compared to the beta-casein of all camel milk breeds and the opposite was true for Lys, Thr, Met and Ile.	Glycine	86-89	casein beta	Bos taurus	144-155
22768954-1	2012	The intrinsic polymer properties of glycine-rich sequences are evaluated with a set of iso-1-cytochrome c variants with N-terminal inserts of the sequence (GGGGGK)(n) for n = 1-5.	Glycine	36-43	cytochrome c, somatic	Homo sapiens	93-105
21735122-3	2012	Our docking results show that the calculated pK (i) values of glycine and L: -glutamate significantly increase (>1) when the NR1 and NR2A S1S2 domains are closing, respectively.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	125-128
21735122-3	2012	Our docking results show that the calculated pK (i) values of glycine and L: -glutamate significantly increase (>1) when the NR1 and NR2A S1S2 domains are closing, respectively.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	133-137
22291198-8	2012	The GDU1 protein encoded by the previously characterized intragenic suppressor mutant log1-1, with an arginine in place of a conserved glycine, failed to interact in the multiple assays, suggesting that the Gdu1D phenotype requires the interaction of GDU1 with LOG2.	Glycine	135-142	glutamine dumper 1	Arabidopsis thaliana	4-8
22566084-2	2012	In this study, Corynebacterium glutamicum ATCC 13032 was engineered de novo by blocking and attenuating the conversion of L-serine to pyruvate and glycine, releasing the feedback inhibition by L-serine to 3-phosphoglycerate dehydrogenase (PGDH), in combination with the co-expression of 3-phosphoglycerate kinase (PGK) and feedback-resistant PGDH (PGDH(r)).	Glycine	147-154	phosphoglycerate kinase	Corynebacterium glutamicum ATCC 13032	287-312
22566084-2	2012	In this study, Corynebacterium glutamicum ATCC 13032 was engineered de novo by blocking and attenuating the conversion of L-serine to pyruvate and glycine, releasing the feedback inhibition by L-serine to 3-phosphoglycerate dehydrogenase (PGDH), in combination with the co-expression of 3-phosphoglycerate kinase (PGK) and feedback-resistant PGDH (PGDH(r)).	Glycine	147-154	phosphoglycerate kinase	Corynebacterium glutamicum ATCC 13032	314-317
22457888-4	2004	Because the integrin alphavbeta3 binds with extracellular matrix proteins (e.g., vitronectin, fibronectin) through the exposed Arg-Gly-Asp tripeptide sequence, RGD-containing peptides have been intensively studied in the past decade as a vector for imaging alphavbeta3 expression (3, 4).	Glycine	131-134	fibronectin 1	Homo sapiens	94-105
22457890-4	2004	Because the integrin alphavbeta3 binds with extracellular matrix proteins (e.g., vitronectin, fibronectin) through the exposed Arg-Gly-Asp tripeptide sequence, RGD-containing peptides have been intensively studied in the past decade as a vector for imaging alphavbeta3 expression (3, 4).	Glycine	131-134	fibronectin 1	Homo sapiens	94-105
22953541-3	2012	In addition, it was stated that enkephalines, VIP and SS are potent to augment the inhibitory effect of GABA and glycine.	Glycine	113-120	vasoactive intestinal peptide	Felis catus	46-49
22132725-2	2012	GLYT1 is the main regulator of synaptic glycine concentrations and catalyses Na+-Cl--glycine co-transport with a 2:1:1 stoichiometry.	Glycine	40-47	solute carrier family 6 member 9	Homo sapiens	0-5
22160777-2	2012	We synthesized a glycine-(Nalpha-Et)lysine-proline-arginine (ITF 1697) peptide that has a potential to inhibit exocytosis of WPB and protect microcirculation.	Glycine	17-24	trefoil factor 3, intestinal	Mus musculus	61-64
21894159-5	2012	RESULTS: Patients with the Gly482Ser polymorphism had significantly improved reductions in the waist/hip ratio, fasting blood glucose, C-reactive protein, blood leukocyte count, serum interleukin-6 and intima-media thickness of the carotid artery, as compared with Gly/Gly patients.	Glycine	27-30	C-reactive protein	Homo sapiens	135-153
21894159-5	2012	RESULTS: Patients with the Gly482Ser polymorphism had significantly improved reductions in the waist/hip ratio, fasting blood glucose, C-reactive protein, blood leukocyte count, serum interleukin-6 and intima-media thickness of the carotid artery, as compared with Gly/Gly patients.	Glycine	27-30	interleukin 6	Homo sapiens	184-197
22236003-5	2012	We examined the inhibitory effects of the amino acids cysteine, histidine and glycine on the induction of NF-kappaB activation, expression of CD62E (E-selectin) and the production of interleukin (IL)-6 in HCAECs stimulated with tumour necrosis factor (TNF)-alpha.	Glycine	78-85	nuclear factor kappa B subunit 1	Homo sapiens	106-115
21674205-6	2012	Here we report on a molecular dynamics (MD) study of single-layer oligomers of the full-length insulin which aimed to identify the structural elements that are important for amyloid stability, and to suggest single glycine mutants in the beta-sheet region that may improve the formulation.	Glycine	215-222	insulin	Homo sapiens	95-102
22371697-3	2012	GCAPs consist of four EF-hand domains and contain N-terminal fatty acylated glycine, which in GCAP1 is required for the normal activation of RetGC.	Glycine	76-83	guanylate cyclase activator 1A	Homo sapiens	94-99
22178676-10	2012	SIGNIFICANCE: We conjecture that glycine increases glycine-mediated postsynaptic inhibition of cuneate neurons, and also blocks GABAergic neurons containing GlyRs which mediate presynaptic inhibition causing temperate NPY release.	Glycine	33-40	neuropeptide Y	Rattus norvegicus	218-221
22323599-4	2012	Herein, we identify mutation of EZH2 A677 to a glycine (A677G) among lymphoma cell lines and primary tumor specimens.	Glycine	47-54	enhancer of zeste 2 polycomb repressive complex 2 subunit	Homo sapiens	32-36
22396402-3	2012	In this study, we show that impaired LTP in adult NCAM-deficient (NCAM(-/-)) mice is restored by increasing the activity of the NMDA subtype of glutamate receptor (GluN) through either reducing the extracellular Mg2+ concentration or applying d-cycloserine (DCS), a partial agonist of the GluN glycine binding site.	Glycine	294-301	neural cell adhesion molecule 1	Mus musculus	50-54
22236003-5	2012	We examined the inhibitory effects of the amino acids cysteine, histidine and glycine on the induction of NF-kappaB activation, expression of CD62E (E-selectin) and the production of interleukin (IL)-6 in HCAECs stimulated with tumour necrosis factor (TNF)-alpha.	Glycine	78-85	interleukin 6	Homo sapiens	183-201
22236003-6	2012	Cysteine, histidine and glycine significantly reduced NF-kappaB activation and inhibitor kappaBalpha (IkappaBalpha) degradation in HCAECs stimulated with TNF-alpha.	Glycine	24-31	nuclear factor kappa B subunit 1	Homo sapiens	54-63
22236003-6	2012	Cysteine, histidine and glycine significantly reduced NF-kappaB activation and inhibitor kappaBalpha (IkappaBalpha) degradation in HCAECs stimulated with TNF-alpha.	Glycine	24-31	NFKB inhibitor alpha	Homo sapiens	102-114
22236003-6	2012	Cysteine, histidine and glycine significantly reduced NF-kappaB activation and inhibitor kappaBalpha (IkappaBalpha) degradation in HCAECs stimulated with TNF-alpha.	Glycine	24-31	tumor necrosis factor	Homo sapiens	154-163
22236003-8	2012	Our results show that glycine, histidine and cysteine can inhibit NF-kappaB activation, IkappaBalpha degradation, CD62E expression and IL-6 production in HCAECs, suggesting that these amino acids may exhibit anti-inflammatory effects during endothelial inflammation.	Glycine	22-29	nuclear factor kappa B subunit 1	Homo sapiens	66-75
22236003-8	2012	Our results show that glycine, histidine and cysteine can inhibit NF-kappaB activation, IkappaBalpha degradation, CD62E expression and IL-6 production in HCAECs, suggesting that these amino acids may exhibit anti-inflammatory effects during endothelial inflammation.	Glycine	22-29	NFKB inhibitor alpha	Homo sapiens	88-100
22236003-8	2012	Our results show that glycine, histidine and cysteine can inhibit NF-kappaB activation, IkappaBalpha degradation, CD62E expression and IL-6 production in HCAECs, suggesting that these amino acids may exhibit anti-inflammatory effects during endothelial inflammation.	Glycine	22-29	interleukin 6	Homo sapiens	135-139
22103682-7	2012	We further demonstrate that the C-terminal glycine-arginine rich domain of nucleolin serves as the predominant binding domain for direct interaction with p53.	Glycine	43-50	tumor protein p53	Homo sapiens	154-157
22103682-9	2012	Conversely, the adjacent glycine-arginine rich domain of nucleolin interacted with p53 causing a modest stimulatory effect on p53 ubiquitination.	Glycine	25-32	tumor protein p53	Homo sapiens	83-86
22103682-9	2012	Conversely, the adjacent glycine-arginine rich domain of nucleolin interacted with p53 causing a modest stimulatory effect on p53 ubiquitination.	Glycine	25-32	tumor protein p53	Homo sapiens	126-129
21573951-3	2012	At nucleotide levels, negatively or uncharged aa, e.g., aspartic and glutamic acid and glycine, which are encoded by the triplets GAN (guanine-adenosine-any nucleotide) or GGN are found more often in R5 strains.	Glycine	87-94	gametogenetin	Homo sapiens	172-175
22156497-5	2012	The Thr(189), Gly(216), and Gly(226) specificity triad in the S1 pocket of GzmH defines its preference for bulky, aromatic residues (Tyr and Phe) at the P1 position.	Glycine	14-17	granzyme H	Homo sapiens	75-79
22138164-2	2012	It is thought that this abnormal functioning can be corrected by increasing availability of the NMDA co-agonist glycine through inhibition of glycine transporter type 1 (GlyT1).	Glycine	112-119	solute carrier family 6 member 9	Homo sapiens	142-168
22138164-2	2012	It is thought that this abnormal functioning can be corrected by increasing availability of the NMDA co-agonist glycine through inhibition of glycine transporter type 1 (GlyT1).	Glycine	112-119	solute carrier family 6 member 9	Homo sapiens	170-175
22138164-4	2012	In vitro, RG1678 noncompetitively inhibited glycine uptake at human GlyT1 with a concentration exhibiting half-maximal inhibition (IC(50)) of 25 nM and competitively blocked [(3)H]ORG24598 binding sites at human GlyT1b in membranes from Chinese hamster ovary cells.	Glycine	44-51	solute carrier family 6 member 9	Homo sapiens	68-73
22233892-0	2012	Activation of glycine site and GluN2B subunit of NMDA receptors is necessary for ERK/CREB signaling cascade in rostral anterior cingulate cortex in rats: implications for affective pain.	Glycine	14-21	Eph receptor B1	Rattus norvegicus	81-84
22363290-11	2012	In silico translation of KCN12 revealed a non-conserved glycine rich stretch located near the carboxy-terminus of the K(IR)2.2 protein.	Glycine	56-63	potassium inwardly rectifying channel subfamily J member 12	Homo sapiens	118-126
22057274-6	2012	In support of our structural data, we demonstrate that substitution of three N-terminal residues (Gly-19, His-25, and Phe-26) of FGF2 (a ligand that does not bind FGFR2b) for the corresponding residues of FGF1 (Phe-16, Asn-22, and Tyr-23) enables the FGF2 triple mutant to bind and activate FGFR2b.	Glycine	98-101	fibroblast growth factor 1	Homo sapiens	205-209
22233892-9	2012	CONCLUSION: Either the glycine site or the GluN2B subunit of NMDARs participates in the phosphorylation of ERK and CREB induced by bath application of NMDA in brain slices or hindpaw injection of 5% formalin in rats, and these might be fundamental molecular mechanisms underlying pain affect.	Glycine	23-30	Eph receptor B1	Rattus norvegicus	107-110
22156497-5	2012	The Thr(189), Gly(216), and Gly(226) specificity triad in the S1 pocket of GzmH defines its preference for bulky, aromatic residues (Tyr and Phe) at the P1 position.	Glycine	28-31	granzyme H	Homo sapiens	75-79
23056045-0	2012	Arginine 16 Glycine Polymorphism in beta2-Adrenergic Receptor Gene is Associated with Obesity, Hyperlipidemia, Hyperleptinemia, and Insulin Resistance in Saudis.	Glycine	12-19	insulin	Homo sapiens	132-139
22044943-11	2012	This study provides first evidence that (1) high-glycine can induce plasticity at glutamatergic synapses in CGCs, and (2) that acute NRG1/ErbB-signaling can regulate glutamatergic plasticity in CGCs.	Glycine	49-56	epidermal growth factor receptor	Homo sapiens	138-142
22184234-0	2012	Deactivation of the Arabidopsis BRASSINOSTEROID INSENSITIVE 1 (BRI1) receptor kinase by autophosphorylation within the glycine-rich loop.	Glycine	119-126	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	32-77
23289226-3	2012	The nucleotide sequence which is complementary contacted with peptide Ala-Glu-Asp-Gly was found in promoter region of interferon gamma gene.	Glycine	82-85	interferon gamma	Homo sapiens	118-134
23027421-4	2012	Glycine levels, in turn, are regulated by glycine type I (GlyT1) transporters, which serve to maintain low subsaturating glycine levels in the vicinity of the NMDA receptor.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	58-63
23027421-4	2012	Glycine levels, in turn, are regulated by glycine type I (GlyT1) transporters, which serve to maintain low subsaturating glycine levels in the vicinity of the NMDA receptor.	Glycine	42-49	solute carrier family 6 member 9	Homo sapiens	58-63
20641959-20	2004	A tripeptide sequence consisting of Arg-Gly-Asp (RGD) is identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including alphavbeta3.	Glycine	40-43	fibrinogen beta chain	Homo sapiens	143-153
22619531-5	2012	PEG hydrogel-coated MIONPs were further functionalized with the fibronectin-derived arginine-glycine-aspartic acid-serine (RGDS) sequence, in order to achieve a biofunctional PEG hydrogel layer around the nanoparticles.	Glycine	93-100	fibronectin 1	Homo sapiens	64-75
22070686-1	2012	The tripeptide glycine-proline-glutamate (GPE) is the naturally cleaved N-terminal tripeptide of insulin-like growth factor-1 (IGF-1) in brain tissues by an acid protease.	Glycine	15-22	insulin like growth factor 1	Homo sapiens	97-125
22264577-5	2012	Examination of the skin fibroblasts demonstrated that ASM activity was reduced to approximately 60% of that observed in control cells, and a newly identified point mutation was found in codon 494 [Gly (GGT)   Cys (TGT)] in the SMPD-1 gene.	Glycine	197-200	sphingomyelin phosphodiesterase 1	Homo sapiens	227-233
21972205-2	2012	Based on the antibody-protein adhesive force maps and phase imaging, it was found that the nanomorphology of the triblock copolymer is conducive to the exposure of the arginine-glycine-aspartic acid (RGD) groups in Fn.	Glycine	177-184	fibronectin 1	Homo sapiens	215-217
22070686-1	2012	The tripeptide glycine-proline-glutamate (GPE) is the naturally cleaved N-terminal tripeptide of insulin-like growth factor-1 (IGF-1) in brain tissues by an acid protease.	Glycine	15-22	insulin like growth factor 1	Homo sapiens	127-132
22859960-9	2012	However, betaine, valine, glycine and glucose were elevated in the urine of HNF1A-MODY subjects compared to the other subgroups.	Glycine	26-33	HNF1 homeobox A	Homo sapiens	76-81
22355255-13	2012	After Gly treatment, all the above-named parameters had reverse changes except for the CAT activity.	Glycine	6-9	catalase	Rattus norvegicus	87-90
21935580-0	2012	Arginine 482 to glycine mutation in ABCG2/BCRP increases etoposide transport             and resistance to the drug in HEK-293 cells.	Glycine	16-23	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	36-41
21935580-0	2012	Arginine 482 to glycine mutation in ABCG2/BCRP increases etoposide transport             and resistance to the drug in HEK-293 cells.	Glycine	16-23	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	42-46
23082118-1	2012	CITED2 is a transcriptional co-activator with 3 conserved domains shared with other CITED family members and a unique Serine-Glycine Rich Junction (SRJ) that is highly conserved in placental mammals.	Glycine	125-132	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	Mus musculus	0-6
23226345-9	2012	We present evidence that phosphorylation of YY1 in the central glycine/alanine (G/A)-rich region is important for DNA binding activity, with a potential phosphorylation/acetylation interplay regulating YY1 function.	Glycine	63-70	YY1 transcription factor	Homo sapiens	44-47
23226345-9	2012	We present evidence that phosphorylation of YY1 in the central glycine/alanine (G/A)-rich region is important for DNA binding activity, with a potential phosphorylation/acetylation interplay regulating YY1 function.	Glycine	63-70	YY1 transcription factor	Homo sapiens	202-205
23133647-3	2012	This is in contrast to mutations within a heparin-binding TB domain (TB5), which is downstream of the arg-gly-asp cell adhesion domain, which can cause Weill-Marchesani syndrome (WMS) or Acromicric (AD) and Geleophysic Dysplasias (GD).	Glycine	106-109	transforming growth factor beta regulator 1	Homo sapiens	69-72
23077649-4	2012	While the binding of a full agonist glycine to LBD of GluN1 is linked to cleft closure and subsequent ion-channel opening, partial agonists are known to activate the receptor only sub-maximally.	Glycine	36-43	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	54-59
21987804-0	2011	Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91.	Glycine	99-106	stromal interaction molecule 1	Homo sapiens	49-54
22693611-6	2012	In vitro studies revealed that COUP-TFII interacts with the C-terminal arginine-glycine repeat (RGG) domain of nucleolin.	Glycine	80-87	nuclear receptor subfamily 2 group F member 2	Homo sapiens	31-40
22509268-7	2012	Analysis of DRB1 and DQB1 protein chain residues showed that the Val/Gly residue at position 86 of the DRB1 chain was the only difference between the protective *16:01- *15:02 alleles and the predisposing *15:01 one.	Glycine	69-72	major histocompatibility complex, class II, DR beta 1	Homo sapiens	12-16
22509268-7	2012	Analysis of DRB1 and DQB1 protein chain residues showed that the Val/Gly residue at position 86 of the DRB1 chain was the only difference between the protective *16:01- *15:02 alleles and the predisposing *15:01 one.	Glycine	69-72	major histocompatibility complex, class II, DR beta 1	Homo sapiens	103-107
23240079-6	2012	These glycine and glutamine residues are conserved among functional GBGT1 genes in Forssman-positive species.	Glycine	6-13	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)	Homo sapiens	68-73
21864610-1	2011	The extracellular levels of the neurotransmitter glycine in the brain are tightly regulated by the glycine transporter 1 (GlyT1) and the clearance rate for glycine depends on its rate of transport and the levels of cell surface GlyT1.	Glycine	49-56	solute carrier family 6 member 9	Homo sapiens	99-120
21864610-1	2011	The extracellular levels of the neurotransmitter glycine in the brain are tightly regulated by the glycine transporter 1 (GlyT1) and the clearance rate for glycine depends on its rate of transport and the levels of cell surface GlyT1.	Glycine	49-56	solute carrier family 6 member 9	Homo sapiens	122-127
21864610-1	2011	The extracellular levels of the neurotransmitter glycine in the brain are tightly regulated by the glycine transporter 1 (GlyT1) and the clearance rate for glycine depends on its rate of transport and the levels of cell surface GlyT1.	Glycine	49-56	solute carrier family 6 member 9	Homo sapiens	228-233
21864610-1	2011	The extracellular levels of the neurotransmitter glycine in the brain are tightly regulated by the glycine transporter 1 (GlyT1) and the clearance rate for glycine depends on its rate of transport and the levels of cell surface GlyT1.	Glycine	99-106	solute carrier family 6 member 9	Homo sapiens	122-127
21889589-1	2011	The recent discovery of heterozygous isocitrate dehydrogenase 2 (IDH2) mutations of residue Arg(140) to Gln(140) or Gly(140) (IDH2(wt/R140Q), IDH2(wt/R140G)) in d-2-hydroxyglutaric aciduria (D-2-HGA) has defined the primary genetic lesion in 50% of D-2-HGA patients, denoted type II.	Glycine	116-119	isocitrate dehydrogenase (NADP(+)) 2	Homo sapiens	65-69
21889589-1	2011	The recent discovery of heterozygous isocitrate dehydrogenase 2 (IDH2) mutations of residue Arg(140) to Gln(140) or Gly(140) (IDH2(wt/R140Q), IDH2(wt/R140G)) in d-2-hydroxyglutaric aciduria (D-2-HGA) has defined the primary genetic lesion in 50% of D-2-HGA patients, denoted type II.	Glycine	116-119	isocitrate dehydrogenase (NADP(+)) 2	Homo sapiens	126-130
21889589-1	2011	The recent discovery of heterozygous isocitrate dehydrogenase 2 (IDH2) mutations of residue Arg(140) to Gln(140) or Gly(140) (IDH2(wt/R140Q), IDH2(wt/R140G)) in d-2-hydroxyglutaric aciduria (D-2-HGA) has defined the primary genetic lesion in 50% of D-2-HGA patients, denoted type II.	Glycine	116-119	isocitrate dehydrogenase (NADP(+)) 2	Homo sapiens	126-130
21785859-4	2011	METHODS: We examined the inhibitory effects of cysteine, histidine or glycine on the induction of nuclear factor-kappaB (NF-kappaB) activation, expression of intracellular adhesion molecule-1 (ICAM-1, CD54) and production of interleukin-8 (IL-8) in THP-1 cells, a human monocytic leukemia cell line, and peripheral blood mononuclear cells (PBMCs) stimulated with tumor necrosis factor-alpha (TNF-alpha).	Glycine	70-77	nuclear factor kappa B subunit 1	Homo sapiens	121-130
21785859-5	2011	RESULTS: Cysteine, histidine and glycine significantly reduced the activation of NF-kappaB in THP-1 cells stimulated with TNF-alpha.	Glycine	33-40	nuclear factor kappa B subunit 1	Homo sapiens	81-90
21785859-5	2011	RESULTS: Cysteine, histidine and glycine significantly reduced the activation of NF-kappaB in THP-1 cells stimulated with TNF-alpha.	Glycine	33-40	tumor necrosis factor	Homo sapiens	122-131
22737219-2	2012	Methyltransferases (MTases) of the DNMT2 family have been shown to have a dual substrate specificity acting on DNA as well as on three specific tRNAs (tRNA(Asp), tRNA(Val), tRNA(Gly)).	Glycine	178-181	tRNA aspartic acid methyltransferase 1	Homo sapiens	35-40
22085831-2	2011	In this study, one tripeptide, GSH (glu-cys-gly), was used to condition gold surfaces and thus influence the adsorption of bovine serum albumin (BSA).	Glycine	44-47	albumin	Homo sapiens	130-143
21864610-7	2011	Furthermore, pre-incubation of the cells with the selective PKCalpha/beta inhibitor Go6976 abolished the downregulation effect of phorbol ester on uptake and phosphorylation, whereas the selective PKCbeta inhibitors (PKCbeta inhibitor or LY333531) prevented the phosphorylation without affecting glycine uptake, defining a specific role of classical PKC on GlyT1 uptake and phosphorylation.	Glycine	296-303	protein kinase C alpha	Homo sapiens	60-73
21864610-7	2011	Furthermore, pre-incubation of the cells with the selective PKCalpha/beta inhibitor Go6976 abolished the downregulation effect of phorbol ester on uptake and phosphorylation, whereas the selective PKCbeta inhibitors (PKCbeta inhibitor or LY333531) prevented the phosphorylation without affecting glycine uptake, defining a specific role of classical PKC on GlyT1 uptake and phosphorylation.	Glycine	296-303	protein kinase C alpha	Homo sapiens	60-63
21864610-8	2011	Taken together, these data suggest that conventional PKCalpha/beta regulates the uptake of glycine, whereas PKCbeta is responsible for GlyT1 phosphorylation.	Glycine	91-98	protein kinase C alpha	Homo sapiens	53-66
21940625-0	2011	Molecular mechanisms of disease for mutations at Gly-90 in rhodopsin.	Glycine	49-52	rhodopsin	Homo sapiens	59-68
21940625-1	2011	Two different mutations at Gly-90 in the second transmembrane helix of the photoreceptor protein rhodopsin have been proposed to lead to different phenotypes.	Glycine	27-30	rhodopsin	Homo sapiens	97-106
22056771-6	2011	Notably, the catalytic cysteine residue in Atg7 is positioned close to the C-terminal glycine of Atg8, its target for thioester formation, potentially eliminating the need for large conformational rearrangements characteristic of other E1s.	Glycine	86-93	GABA type A receptor associated protein like 1	Homo sapiens	97-101
21785859-4	2011	METHODS: We examined the inhibitory effects of cysteine, histidine or glycine on the induction of nuclear factor-kappaB (NF-kappaB) activation, expression of intracellular adhesion molecule-1 (ICAM-1, CD54) and production of interleukin-8 (IL-8) in THP-1 cells, a human monocytic leukemia cell line, and peripheral blood mononuclear cells (PBMCs) stimulated with tumor necrosis factor-alpha (TNF-alpha).	Glycine	70-77	nuclear factor kappa B subunit 1	Homo sapiens	98-119
21880725-5	2011	We found that Ala-to-Gly exchange in human 15-LOX2 and human platelet 12-LOX induced major alterations in the reaction specificity with an increase of specific R-oxygenation products.	Glycine	21-24	arachidonate 15-lipoxygenase type B	Homo sapiens	43-50
21746848-2	2011	NMDA receptors are obligate heterotetramers typically composed of glycine-binding GluN1 and glutamate-binding GluN2 subunits that gate in a concerted fashion, requiring all four ligands to bind for subsequent opening of the channel pore.	Glycine	66-73	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	82-87
22004682-6	2011	RESULTS: Down regulation of uPA/uPAR, either singly or simultaneously, in U251 MG and tumor xenografts inhibited the cleavage of the Notch receptor between the Gly 1743 and Val 1744 positions, thereby suggesting inhibition of activated cytosolic fragment-related Notch gene transcription.	Glycine	160-163	plasminogen activator, urokinase	Homo sapiens	28-31
21936798-3	2011	To this end, hydrogen-transfer reactions have been observed between cysteine thiyl radicals and glycine, alanine, serine, valine and leucine in both model peptides and a protein, insulin.	Glycine	96-103	insulin	Homo sapiens	179-186
23071946-7	2011	Amino acids like alanine, glycine, lysine, serine and 4-hydroxy proline showed strong stabilizing effect on catalase during lyophilization by protecting catalase activity above 95%, whereas valine and cysteine hydrochloride showed destabilizing effect on catalase.	Glycine	26-33	catalase	Homo sapiens	108-116
23071946-7	2011	Amino acids like alanine, glycine, lysine, serine and 4-hydroxy proline showed strong stabilizing effect on catalase during lyophilization by protecting catalase activity above 95%, whereas valine and cysteine hydrochloride showed destabilizing effect on catalase.	Glycine	26-33	catalase	Homo sapiens	153-161
23071946-7	2011	Amino acids like alanine, glycine, lysine, serine and 4-hydroxy proline showed strong stabilizing effect on catalase during lyophilization by protecting catalase activity above 95%, whereas valine and cysteine hydrochloride showed destabilizing effect on catalase.	Glycine	26-33	catalase	Homo sapiens	153-161
20641531-7	2004	A tripeptide sequence consisting of Arg-Gly-Asp (RGD) is identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including alphavbeta3.	Glycine	40-43	fibrinogen beta chain	Homo sapiens	143-153
21868366-3	2011	The arginine- and glycine-rich region of FMRP (the RGG box) is unique; it is the high-affinity RNA-binding motif in FMRP and is encoded by exon 15.	Glycine	18-25	fragile X messenger ribonucleoprotein 1	Homo sapiens	41-45
21868366-3	2011	The arginine- and glycine-rich region of FMRP (the RGG box) is unique; it is the high-affinity RNA-binding motif in FMRP and is encoded by exon 15.	Glycine	18-25	fragile X messenger ribonucleoprotein 1	Homo sapiens	116-120
21529830-8	2011	K(m), V(max), and % gly-sar transported by PepT1 were calculated and compared.	Glycine	20-23	solute carrier family 15 member 1	Homo sapiens	43-48
21529830-9	2011	RESULTS: K(m), V(max), and % gly-sar transported by PepT1 varied from 0.7 to 2.4 mM, 8.4 to 21.0 nmol/mg protein/10 min, and 69% to 87%, respectively.	Glycine	29-32	solute carrier family 15 member 1	Homo sapiens	52-57
21315124-6	2011	Application of the inhibitory neurotransmitters, GABA (0.1-1000 muM) or glycine (0.1-1000 muM) evoked concentration dependent currents.	Glycine	72-79	latexin	Homo sapiens	90-93
21315124-8	2011	Responses to glycine were reversibly blocked by strychnine (10 muM) consistent with glycine-gated chloride channels.	Glycine	13-20	latexin	Homo sapiens	63-66
21315124-8	2011	Responses to glycine were reversibly blocked by strychnine (10 muM) consistent with glycine-gated chloride channels.	Glycine	84-91	latexin	Homo sapiens	63-66
21762704-5	2011	Gly injection also induced protein carbonyl formation, as well as elevation of the activities of glutathione peroxidase, glutathione reductase, catalase and superoxide dismutase.	Glycine	0-3	catalase	Homo sapiens	144-152
21529934-1	2011	Platelet adhesion to adsorbed plasma proteins, such as fibrinogen (Fg), has been conventionally thought to be mediated by the GPIIb/IIIa receptor binding to Arg-Gly-Asp (RGD)-like motifs in the adsorbed protein.	Glycine	161-164	fibrinogen beta chain	Homo sapiens	55-65
21507611-5	2011	This mutation causes one highly conserved glycine residue transit to arginine on the 10th transmembrane region of PTCH protein.	Glycine	42-49	patched 1	Homo sapiens	114-118
21945317-3	2011	The metabolite analysis revealed the contents of glucose, glycine, betaine, phosphocholine, pyruvate and lactate involved in the hypoxia-inducible factor (HIF)-1-dependent glycolytic pathway were significantly lower in cells treated with siARNT2.	Glycine	58-65	hypoxia inducible factor 1 subunit alpha	Homo sapiens	129-161
21849499-7	2011	The cleavage site in SelK was identified between Arg(81) and Gly(82) and the resulting truncated SelK was shown to lack selenocysteine, the amino acid that defines selenoproteins.	Glycine	61-64	selenoprotein K	Mus musculus	21-25
21764223-5	2011	Measures which enhance adipocyte insulin sensitivity--such as pioglitazone, astaxanthin, and spirulina--may also be helpful in this regard, as may agents that boost hepatocyte capacity for fatty acid oxidation, such as metformin, carnitine, hydroxycitrate, long-chain omega-3 fats, and glycine.	Glycine	286-293	insulin	Homo sapiens	33-40
21892948-10	2011	The mutation results in substitution of arginine for the highly conserved glycine at residue 199 located at the p53 dimer-dimer interface.	Glycine	74-81	tumor protein p53	Homo sapiens	112-115
21862853-2	2011	The carbon (C 1s) binding energy spectra of the aliphatic amino acids are derived from the C 1s spectrum of glycine (the parent spectrum) by the addition of spectral peaks, depending on the alkyl side chains, appearing in the lower energy region IP &lt; 290 eV (where IP is the ionization potential).	Glycine	108-115	complement C1s	Homo sapiens	12-16
21862853-2	2011	The carbon (C 1s) binding energy spectra of the aliphatic amino acids are derived from the C 1s spectrum of glycine (the parent spectrum) by the addition of spectral peaks, depending on the alkyl side chains, appearing in the lower energy region IP &lt; 290 eV (where IP is the ionization potential).	Glycine	108-115	complement C1s	Homo sapiens	91-95
21703856-5	2011	The six investigated compounds were all defined as high affinity ligands (K(i)-values &lt;0.5 mM) for hPEPT1 by measuring the concentration dependent inhibition of apical [(14)C]Gly-Sar uptake in Caco-2 cells.	Glycine	178-181	solute carrier family 15 member 1	Homo sapiens	102-108
21453287-6	2011	Unlike the reversible metabolism of glucocorticoids, 11beta-HSD1 mediated solely 7-oxo reduction of 7-oxoLCA and its taurine and glycine conjugates.	Glycine	129-136	hydroxysteroid 11-beta dehydrogenase 1	Homo sapiens	53-64
21718689-3	2011	CRP2 protein directly associated with F-actin through its N-terminal LIM domain and Gly-rich region, as determined by ELISA.	Glycine	84-87	cysteine rich protein 2	Mus musculus	0-4
21653836-2	2011	HIV and SIV borrow the host-derived N-myristoyl-transferase and its substrate, myristoyl-CoA, for coupling a saturated C(14) fatty acid (myristic acid) to the N-terminal glycine residue of the Nef protein.	Glycine	170-177	S100 calcium binding protein B	Homo sapiens	193-196
21666516-2	2011	Application of glycine impeded radial migration only in the presence of the glycine-transport blockers, ALX-5407 and ALX-1393.	Glycine	15-22	formyl peptide receptor 3	Mus musculus	104-107
21666516-2	2011	Application of glycine impeded radial migration only in the presence of the glycine-transport blockers, ALX-5407 and ALX-1393.	Glycine	15-22	formyl peptide receptor 3	Mus musculus	117-120
21539943-4	2011	GIP adopts an alpha-helical conformation between residues Phe(6)-Gly(31) and Ala(13)-Gln(29) for micellar and bicellar media, respectively.	Glycine	65-68	gastric inhibitory polypeptide	Rattus norvegicus	0-3
21558795-2	2011	Recently we studied glycine receptors (GlyRs) in motoneurons in an ALS mouse model expressing a mutant form of human superoxide dismutase-1 with a Gly93 Ala substitution (G93A-SOD1).	Glycine	20-27	superoxide dismutase 1	Homo sapiens	117-139
21558795-2	2011	Recently we studied glycine receptors (GlyRs) in motoneurons in an ALS mouse model expressing a mutant form of human superoxide dismutase-1 with a Gly93 Ala substitution (G93A-SOD1).	Glycine	20-27	superoxide dismutase 1	Homo sapiens	176-180
21329384-6	2011	Two calcyclin peptides with an extra glycine inserted in the middle of the amino acid sequence were synthesized and used as an internal reference.	Glycine	37-44	S100 calcium binding protein A6	Homo sapiens	4-13
21584310-6	2011	PAD4 citrullinates the Arg-Gly repeat region of RPS2, which is also an established site for Arg methylation by protein arginine methyltransferase 3 (PRMT3).	Glycine	27-30	ribosomal protein S2	Homo sapiens	48-52
21584310-6	2011	PAD4 citrullinates the Arg-Gly repeat region of RPS2, which is also an established site for Arg methylation by protein arginine methyltransferase 3 (PRMT3).	Glycine	27-30	protein arginine methyltransferase 3	Homo sapiens	111-147
21584310-6	2011	PAD4 citrullinates the Arg-Gly repeat region of RPS2, which is also an established site for Arg methylation by protein arginine methyltransferase 3 (PRMT3).	Glycine	27-30	protein arginine methyltransferase 3	Homo sapiens	149-154
21621521-6	2011	The bioinformatic analysis demonstrates the interface of the two pro-triplets SSS (Ser-Ser-Ser) and YGS (Tyr-Gly-Ser) located in the extracellular and intracellular domain of the FGFR1.	Glycine	109-112	fibroblast growth factor receptor 1	Homo sapiens	179-184
21642970-1	2011	We have determined the solution structure of the complex between an arginine-glycine-rich RGG peptide from the human fragile X mental retardation protein (FMRP) and an in vitro-selected guanine-rich (G-rich) sc1 RNA.	Glycine	77-84	fragile X messenger ribonucleoprotein 1	Homo sapiens	117-153
21491921-10	2011	Site-directed mutagenesis experiments demonstrated that glycine 185 is a critical residue for the direct inhibitory effect of Lipodox on Pgp.	Glycine	56-63	ATP binding cassette subfamily B member 1	Homo sapiens	137-140
22214528-2	2011	The aim of this study was to detect the effect of increased expression of RAGE on the angiogenic response to limb ischemia in diabetes by targeting alphavbeta3 integrin with 99mTc-labeled Arg-Gly-Asp (RGD).	Glycine	192-195	advanced glycosylation end product-specific receptor	Mus musculus	74-78
21642970-1	2011	We have determined the solution structure of the complex between an arginine-glycine-rich RGG peptide from the human fragile X mental retardation protein (FMRP) and an in vitro-selected guanine-rich (G-rich) sc1 RNA.	Glycine	77-84	fragile X messenger ribonucleoprotein 1	Homo sapiens	155-159
21454582-5	2011	A unique Gly-rich region in HER2 following the alpha-helix C is responsible for increased conformational flexibility within the active site and could explain the low intrinsic catalytic activity previously reported for HER2.	Glycine	9-12	erb-b2 receptor tyrosine kinase 2	Homo sapiens	28-32
21487005-6	2011	Conversion of serine to glycine at an ERK1/2 phosphorylation site (S281G) abolished the cAMP activation of TRPC6 as determined by whole-cell and cell-attached single-channel patch recordings.	Glycine	24-31	mitogen-activated protein kinase 3	Homo sapiens	38-44
21668335-2	2011	Substitution of glycine for asparagine and addition of two arginine residues raise the isoelectric point of insulin glargine and result in microprecipitates, delaying absorption from subcutaneous tissue.	Glycine	16-23	insulin	Homo sapiens	108-115
20499205-4	2011	The distribution of Cd (II) and Pb (II) in alanine (Ala), aspartic acid (Asp), glutamic acid (Glu), glycine (Gly), histidine (His), methionine (Met), phenylalanine (Phe), serine (Ser), and threonine (Thr) were analyzed by monitoring changes in the concentration of free amino acids by HPLC/IC.	Glycine	100-107	submaxillary gland androgen regulated protein 3B	Homo sapiens	20-39
21454582-5	2011	A unique Gly-rich region in HER2 following the alpha-helix C is responsible for increased conformational flexibility within the active site and could explain the low intrinsic catalytic activity previously reported for HER2.	Glycine	9-12	erb-b2 receptor tyrosine kinase 2	Homo sapiens	219-223
21916253-3	2011	Also, enkephalins, VIP and SS were found to amplify the inhibiting action of GABA and glycine.	Glycine	86-93	vasoactive intestinal peptide	Felis catus	19-22
21396938-3	2011	Sequence alignments of GSL-binding proteins against the GBM of alpha-synuclein allowed the establishment of a consensus GBM sequence defined as K/H/R/-X(1-4)-Y/F-X(4-5)-K/H/R, where at least one of the X(1-4) residues is glycine.	Glycine	221-228	cathepsin A	Homo sapiens	23-26
21345800-9	2011	Furthermore, comparison of these mutant and wild type structures strongly suggests that the Gly(631)-Asn(635) loop movement controls NADPH binding and NADP(+) release; this loop movement in turn facilitates the flavin domain movement, allowing electron transfer from FMN to the CYPOR redox partners.	Glycine	92-95	cytochrome p450 oxidoreductase	Homo sapiens	278-283
21439408-3	2011	We have previously observed that VIP-G (glycine-extended VIP) is unstructured in solution, as evidenced by the limited NMR chemical shift dispersion.	Glycine	40-47	vasoactive intestinal peptide	Homo sapiens	33-36
21439408-3	2011	We have previously observed that VIP-G (glycine-extended VIP) is unstructured in solution, as evidenced by the limited NMR chemical shift dispersion.	Glycine	40-47	vasoactive intestinal peptide	Homo sapiens	57-60
21454656-1	2011	The conformational changes in the agonist binding domain of the glycine-binding GluN1 and glutamate-binding GluN2A subunits of the N-methyl D-aspartic acid receptor upon binding agonists of varying efficacy have been investigated by luminescence resonance energy transfer (LRET) measurements.	Glycine	64-71	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	80-85
21126544-0	2011	Site-directed mutagenesis of the glycine-rich loop of death associated protein kinase (DAPK) identifies it as a key structure for catalytic activity.	Glycine	33-40	death associated protein kinase 1	Homo sapiens	54-85
21126544-0	2011	Site-directed mutagenesis of the glycine-rich loop of death associated protein kinase (DAPK) identifies it as a key structure for catalytic activity.	Glycine	33-40	death associated protein kinase 1	Homo sapiens	87-91
21126544-3	2011	(2009) that conformational selection in DAPK"s glycine-rich region is key for catalytic activity.	Glycine	47-54	death associated protein kinase 1	Homo sapiens	40-44
21126544-5	2011	The glycine-rich loop exhibits localized differences in structure among DAPK conformations that correlate with different stages of the catalytic cycle.	Glycine	4-11	death associated protein kinase 1	Homo sapiens	72-76
21126544-7	2011	High resolution X-ray crystal structures of various conformations of the Q23V mutant DAPK and their superimposition with the corresponding conformations from wild type catalytic domain reveal localized changes in the glycine-rich region.	Glycine	217-224	death associated protein kinase 1	Homo sapiens	85-89
21454242-11	2011	The Arg52Gly mutation replaces the normal arginine residue (CGC) with a glycine residue (GGC) at position 52 of the resultant menin protein.	Glycine	72-79	menin 1	Homo sapiens	126-131
21454242-14	2011	Nonconservative replacement of arginine, a small, neutral amino acid, with glycine, a bulky positively charged amino acid, could potentially have a deleterious effect on the menin protein.	Glycine	75-82	menin 1	Homo sapiens	174-179
21367887-7	2011	Substitution of the glycine residues and triserine motif present in the p15 TMD also impaired or eliminated the fusion-promoting activity of the p15 TMD.	Glycine	20-27	cyclin dependent kinase inhibitor 2B	Homo sapiens	72-75
21412957-4	2011	Extensive SAR studies of the C-terminal CGRP (27-37) region identified a novel cyclic structure: Bz-Val-Tyr-cyclo[Cys-Thr-Asp-Val-Gly-Pro-Phe-Cys]-Phe-NH(2) (23) with a kb value of 0.126 nM against the cloned human CGRP receptor.	Glycine	130-133	calcitonin related polypeptide alpha	Homo sapiens	40-44
21412957-4	2011	Extensive SAR studies of the C-terminal CGRP (27-37) region identified a novel cyclic structure: Bz-Val-Tyr-cyclo[Cys-Thr-Asp-Val-Gly-Pro-Phe-Cys]-Phe-NH(2) (23) with a kb value of 0.126 nM against the cloned human CGRP receptor.	Glycine	130-133	calcitonin related polypeptide alpha	Homo sapiens	215-219
21367887-7	2011	Substitution of the glycine residues and triserine motif present in the p15 TMD also impaired or eliminated the fusion-promoting activity of the p15 TMD.	Glycine	20-27	cyclin dependent kinase inhibitor 2B	Homo sapiens	145-148
21122942-4	2011	Our results indicated that growing the ATP-depleted MDCK cells in glycine-containing media increased the level of phosphorylated extracellular signal-regulated kinase 1 and 2 (ERK1/2), Ets-like transcription factor-1 (Elk1), AKT, and Forkhead box O-class 1 (FoxO1), decreased the level of phosphorylated p38 mitogen-activated protein kinase, while having little effect on the phosphorylation status of c-Jun N-terminal kinase 1 and 2.	Glycine	66-73	mitogen-activated protein kinase 1	Canis lupus familiaris	176-182
21210071-1	2011	Glycine N-methyltransferase (GNMT) is a major hepatic enzyme that converts S-adenosylmethionine to S-adenosylhomocysteine while generating sarcosine from glycine, hence it can regulate mediating methyl group availability in mammalian cells.	Glycine	154-161	glycine N-methyltransferase	Homo sapiens	0-27
21210071-1	2011	Glycine N-methyltransferase (GNMT) is a major hepatic enzyme that converts S-adenosylmethionine to S-adenosylhomocysteine while generating sarcosine from glycine, hence it can regulate mediating methyl group availability in mammalian cells.	Glycine	154-161	glycine N-methyltransferase	Homo sapiens	29-33
21280612-4	2011	The uptake of glycylsarcosine (Gly-Sar, a typical substrate of PepT1) by Caco-2 cells could be inhibited by compound 4a in a concentration-dependent manner.	Glycine	31-34	solute carrier family 15 member 1	Homo sapiens	63-68
21122942-0	2011	Glycine-induced cytoprotection is mediated by ERK1/2 and AKT in renal cells with ATP depletion.	Glycine	0-7	mitogen-activated protein kinase 1	Canis lupus familiaris	46-52
21122942-4	2011	Our results indicated that growing the ATP-depleted MDCK cells in glycine-containing media increased the level of phosphorylated extracellular signal-regulated kinase 1 and 2 (ERK1/2), Ets-like transcription factor-1 (Elk1), AKT, and Forkhead box O-class 1 (FoxO1), decreased the level of phosphorylated p38 mitogen-activated protein kinase, while having little effect on the phosphorylation status of c-Jun N-terminal kinase 1 and 2.	Glycine	66-73	forkhead box O1	Canis lupus familiaris	234-256
21122942-4	2011	Our results indicated that growing the ATP-depleted MDCK cells in glycine-containing media increased the level of phosphorylated extracellular signal-regulated kinase 1 and 2 (ERK1/2), Ets-like transcription factor-1 (Elk1), AKT, and Forkhead box O-class 1 (FoxO1), decreased the level of phosphorylated p38 mitogen-activated protein kinase, while having little effect on the phosphorylation status of c-Jun N-terminal kinase 1 and 2.	Glycine	66-73	forkhead box O1	Canis lupus familiaris	258-263
21122942-6	2011	We also showed that treating MDCK cells with ERK1/2 inhibitor PD98059 or AKT inhibitor LY294002 diminished cytoprotection against cell death by glycine, as determined by assessment of lactate dehydrogenase release and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide activity.	Glycine	144-151	mitogen-activated protein kinase 1	Canis lupus familiaris	45-51
21122942-9	2011	Taken together, our results suggest that the ERK1/2 and AKT signaling pathways are involved in the glycine-GlyR protection of MDCK cells against death induced by ATP depletion.	Glycine	99-106	mitogen-activated protein kinase 1	Canis lupus familiaris	45-51
21153865-6	2011	h[Gly(2)]GLP-2 pretreatment prevented the TNF-alpha/Act D-induced oxidative injury by a significant reduction in the intestinal injury, apoptotic index, expression of active caspase-3, lipid peroxidation and GSH levels, GPx and SOD activities; a markedly increase in cell proliferation, and CAT activity.	Glycine	2-5	tumor necrosis factor	Mus musculus	42-51
21330192-1	2011	BACKGROUND: Aspartic acid to glycine substitution (D222G) of haemagglutinin subunit (HA1) was associated with adverse outcomes in 2009 pandemic influenza A (H1N1) infections.	Glycine	29-36	Rho GTPase activating protein 45	Homo sapiens	85-88
21233196-5	2011	The glycine (50 nmol)-evoked diuresis and natriuresis were abolished in rats continuously infused intravenously with [Arg(8)]-vasopressin.	Glycine	4-11	arginine vasopressin	Rattus norvegicus	126-137
21233196-10	2011	Although endogenous PVN glycine inputs elicit a tonic control of heart rate and RSNA, the renal excretory responses to PVN glycine seem to be caused primarily by the inhibition of arginine vasopressin secretion.	Glycine	123-130	arginine vasopressin	Rattus norvegicus	189-200
21153865-6	2011	h[Gly(2)]GLP-2 pretreatment prevented the TNF-alpha/Act D-induced oxidative injury by a significant reduction in the intestinal injury, apoptotic index, expression of active caspase-3, lipid peroxidation and GSH levels, GPx and SOD activities; a markedly increase in cell proliferation, and CAT activity.	Glycine	2-5	catalase	Mus musculus	291-294
21262302-6	2011	And JBP485 uptake was also significantly inhibited by glycylsarcosine (Gly-Sar, a typical substrate for PEPT1 transporters), JBP923 (a derivative of JBP485), and cephalexin (CEX, a beta-lactam antibiotic and a known substrate of PEPT1) in Caco-2 cells.	Glycine	71-74	solute carrier family 15 member 1	Homo sapiens	104-109
20641300-6	2004	A tripeptide sequence consisting of Arg-Gly-Asp (RGD) was identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including alphavbeta3.	Glycine	40-43	fibrinogen beta chain	Homo sapiens	144-154
21301787-0	2011	Characterisation of factor IX with a glycine-to-valine missense mutation at residue 190 in a patient with severe haemophilia B.	Glycine	37-44	coagulation factor IX	Homo sapiens	20-29
21301787-1	2011	A patient with severe haemophilia B with a glycine-to-valine missense mutation at residue 190 (c25, chymotrypsin numbering) in factor IX (FIX; FIX-G190V or FIX-FuChou) had &lt;1% of normal FIX clotting activity and 36% of normal FIX antigen levels (cross-reacting material- reduced, CRMr).	Glycine	43-50	coagulation factor IX	Homo sapiens	127-136
21115079-6	2011	G3.5-Glycine-SN38 and G3.5-betaAlanine-SN38 showed IC50 values of 0.60 and 3.59 muM, respectively, in HT-29 cells treated for 48 h, indicating the efficacy of the drug delivery system in colorectal cancer cells with longer incubation time.	Glycine	5-12	latexin	Homo sapiens	80-83
21282328-3	2011	Arabidopsis thaliana cold shock domain protein 4 (AtCSP4) contains a well conserved cold shock domain (CSD) and glycine-rich motifs interspersed by two retroviral-like CCHC zinc fingers.	Glycine	112-119	glycine-rich protein 2B	Arabidopsis thaliana	21-48
21282328-3	2011	Arabidopsis thaliana cold shock domain protein 4 (AtCSP4) contains a well conserved cold shock domain (CSD) and glycine-rich motifs interspersed by two retroviral-like CCHC zinc fingers.	Glycine	112-119	glycine-rich protein 2B	Arabidopsis thaliana	50-56
21189265-7	2011	Expression of catalytically-inactive HL (HL(SG)) (Ser-145 at the catalytic site was substituted with Gly) in the cells also resulted in decreased secretion of VLDL-[(3)H]TAG.	Glycine	101-104	lipase C, hepatic type	Rattus norvegicus	37-39
21357733-3	2011	Here, we examined the role of Asp-433 and Gly-432 in channel kinetics, ion selectivity, conductance, and Ca(2+) block in lamprey ASIC1 that is a channel with little intrinsic desensitization in the pH range of maximal activity, pH 7.0.	Glycine	42-45	acid sensing ion channel subunit 1	Gallus gallus	129-134
21357733-10	2011	The constriction made by Asp-433 and Gly-432 does not select for ions in the open conformation, implying that the closing gate and selectivity filter are separate structural elements in the ion pathway of ASIC1.	Glycine	37-40	acid sensing ion channel subunit 1	Gallus gallus	205-210
21189265-7	2011	Expression of catalytically-inactive HL (HL(SG)) (Ser-145 at the catalytic site was substituted with Gly) in the cells also resulted in decreased secretion of VLDL-[(3)H]TAG.	Glycine	101-104	lipase C, hepatic type	Rattus norvegicus	41-47
21173160-5	2011	We quantify the association of TDP-43 with stress granules over time and show that stress granule association and size are dependent on the glycine-rich region of TDP-43, which harbors the majority of pathogenic mutations.	Glycine	140-147	TAR DNA binding protein	Homo sapiens	31-37
21321280-6	2011	METHODS: A series of recombinant derivatives of the HER2-binding Z(HER2)(:342) Affibody molecule with a C-terminal chelating sequence, -GXXC (X denoting glycine, serine, lysine, or glutamate), was designed.	Glycine	153-160	erb-b2 receptor tyrosine kinase 2	Homo sapiens	52-56
21321280-6	2011	METHODS: A series of recombinant derivatives of the HER2-binding Z(HER2)(:342) Affibody molecule with a C-terminal chelating sequence, -GXXC (X denoting glycine, serine, lysine, or glutamate), was designed.	Glycine	153-160	erb-b2 receptor tyrosine kinase 2	Homo sapiens	67-71
21173160-5	2011	We quantify the association of TDP-43 with stress granules over time and show that stress granule association and size are dependent on the glycine-rich region of TDP-43, which harbors the majority of pathogenic mutations.	Glycine	140-147	TAR DNA binding protein	Homo sapiens	163-169
21414903-7	2011	Glycine-evoked current density was significantly smaller in the G93A-SOD1 motoneurons compared with control.	Glycine	0-7	superoxide dismutase 1, soluble	Mus musculus	69-73
21249762-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
20868722-10	2011	Dug1p activity towards Cys-Gly peptide is significantly reduced (~ 70%) in the presence of Glu-Cys-Gly.	Glycine	27-30	metallodipeptidase	Saccharomyces cerevisiae S288C	0-5
20868722-11	2011	Therefore, Dug1p can recognize a variety of oligopeptides, but has evolved with post-binding screening potential to hydrolyze Cys-Gly peptides selectively.	Glycine	130-133	metallodipeptidase	Saccharomyces cerevisiae S288C	11-16
21071185-1	2011	The complex formed due to the interaction of the amphiphilic betablocker acebutolol with fibrinogen in a buffer solution (50mN glycine, pH of 8.5) has been investigated using a multipronged physicochemical approach.	Glycine	127-134	fibrinogen beta chain	Homo sapiens	89-99
21123178-4	2011	RHA contains a conserved ATPase-dependent helicase core that is flanked by two alpha-beta-beta-beta-alpha double-stranded RNA-binding domains at the N terminus and repeated arginine-glycine residues at the C terminus.	Glycine	182-189	DExH-box helicase 9	Homo sapiens	0-3
21147219-6	2011	The K(i)-values of H-X(aa)-Ser-OH dipeptides for hPEPT1 in MDCK/hPEPT1 cells ranged from 0.14 mM (logIC(50)=-0.85 +- 0.06) for H-Tyr-Ser-OH to 0.89 mM (logIC(50)=-0.09 +- 0.02) for H-Gly-Ser-OH, as measured in a competition assay with [(14)C]Gly-Sar.	Glycine	183-186	solute carrier family 15 member 1	Homo sapiens	49-55
20641535-0	2004	(111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1).	Glycine	13-16	gastrin releasing peptide receptor	Homo sapiens	228-241
20641535-0	2004	(111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1).	Glycine	13-16	gastrin releasing peptide receptor	Homo sapiens	243-247
21298005-8	2011	Glycine transporters are the most closely related SLC6 transporters to Ntl, suggesting that Ntl functions as a glycine transporter in developing sperm, where augmentation of the cytosolic pool of glycine may be required for the polyglycylation of the massive amounts of tubulin in the fly"s giant sperm.	Glycine	111-118	Neurotransmitter transporter-like	Drosophila melanogaster	71-74
21298005-8	2011	Glycine transporters are the most closely related SLC6 transporters to Ntl, suggesting that Ntl functions as a glycine transporter in developing sperm, where augmentation of the cytosolic pool of glycine may be required for the polyglycylation of the massive amounts of tubulin in the fly"s giant sperm.	Glycine	111-118	Neurotransmitter transporter-like	Drosophila melanogaster	92-95
21628872-2	2011	The specific glycine transporter GLYT1 is found throughout the human intestine where it is responsible for some 30-50% of glycine uptake into intestinal epithelial cells across the basolateral membrane and appears to function to maintain glycine supply to enterocytes and colonocytes.	Glycine	122-129	solute carrier family 6 member 9	Homo sapiens	33-38
21204228-2	2011	Here, we describe a COL2A1 sequence variant, c.2957C&gt;T, p.Pro986Leu in the triple helical domain, which is a Y-position substitution in exon 41 of the repeating triplet sequence Gly-X-Y of the proalpha1(II) chain.	Glycine	181-184	collagen type II alpha 1 chain	Homo sapiens	20-26
21204228-12	2011	The sequence variant in this family is the only reported Y-position proline substitution in the triple helical domain (Gly-X-Y) of the proalpha1(II) coded by the COL2A1 gene.	Glycine	119-122	collagen type II alpha 1 chain	Homo sapiens	162-168
21628872-2	2011	The specific glycine transporter GLYT1 is found throughout the human intestine where it is responsible for some 30-50% of glycine uptake into intestinal epithelial cells across the basolateral membrane and appears to function to maintain glycine supply to enterocytes and colonocytes.	Glycine	13-20	solute carrier family 6 member 9	Homo sapiens	33-38
21628872-3	2011	This paper reviews current knowledge of GLYT1 and presents recent evidence supporting its essential role in glycine mediated cytoprotection in intestinal absorptive cells.	Glycine	108-115	solute carrier family 6 member 9	Homo sapiens	40-45
21355838-3	2011	One means of enhancing NMDA receptor neurotransmission is to increase the availability of the obligatory co-agonist glycine at modulatory site on the NMDA receptors through the inhibition of glycine transporter-1 (GlyT-1) on glial cells.	Glycine	116-123	solute carrier family 6 member 9	Homo sapiens	191-212
21389620-1	2011	Mammalian thioredoxin reductases (TrxRs) contain selenium as selenocysteine (Sec) in the C-terminal redox center -Gly-Cys-Sec-Gly-OH to reduce Trx and other substrates; a Sec-to-Cys substitution in mammalian TrxR yields an almost inactive enzyme.	Glycine	114-117	Thioredoxin reductase-1	Drosophila melanogaster	34-38
21389620-1	2011	Mammalian thioredoxin reductases (TrxRs) contain selenium as selenocysteine (Sec) in the C-terminal redox center -Gly-Cys-Sec-Gly-OH to reduce Trx and other substrates; a Sec-to-Cys substitution in mammalian TrxR yields an almost inactive enzyme.	Glycine	126-129	Thioredoxin reductase-1	Drosophila melanogaster	34-38
21355838-3	2011	One means of enhancing NMDA receptor neurotransmission is to increase the availability of the obligatory co-agonist glycine at modulatory site on the NMDA receptors through the inhibition of glycine transporter-1 (GlyT-1) on glial cells.	Glycine	116-123	solute carrier family 6 member 9	Homo sapiens	214-220
20530987-5	2011	RESULTS: The 1st patient had a single missense mutation in his copy of the KAL1 gene, a T G transversion in codon 134 that results in replacement of cysteine by gly cine.	Glycine	161-169	anosmin 1	Homo sapiens	75-79
21916235-0	2011	[Study of gly-proline-containing peptides (PGP and GPGPGP) degradation by aggressive factors in vitro].	Glycine	10-13	phosphoglycolate phosphatase	Rattus norvegicus	43-46
21921380-8	2011	We concluded she had RTH clinically, and we demonstrated by direct sequence analysis a mutation of the TRbeta gene, causing replacement of a glycine (G) with arginine (R) at codon 251.	Glycine	141-148	T cell receptor beta locus	Homo sapiens	103-109
21175814-7	2011	Cytokine levels (tumor necrosis factor-alpha, interleukin-8) and hepatocellular injury (aspartate aminotransferase and alanine aminotransferase) were significantly reduced by glycine administration.	Glycine	175-182	interleukin-8	Oryctolagus cuniculus	46-59
20811396-1	2011	Fibronectin (FN) is required for embryogenesis, morphogenesis, and wound repair, and its Arg-Gly-Asp-containing central cell-binding domain (CCBD) is essential for mesenchymal cell survival and growth.	Glycine	93-96	fibronectin 1	Homo sapiens	0-11
20811396-1	2011	Fibronectin (FN) is required for embryogenesis, morphogenesis, and wound repair, and its Arg-Gly-Asp-containing central cell-binding domain (CCBD) is essential for mesenchymal cell survival and growth.	Glycine	93-96	fibronectin 1	Homo sapiens	13-15
21204315-13	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (e.g., vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	140-150
21797820-14	2011	The P-Akt level was decreased in Gly group and upregulated significantly in fasudil group.	Glycine	33-36	AKT serine/threonine kinase 1	Rattus norvegicus	6-9
20695776-3	2011	During tissue development, repair, and regeneration of epithelial tissues, cells must interact with an interstitial fibronectin (Fn)-rich matrix, which has been shown to direct a more migratory/repair phenotype, presumably through interaction with Fn"s cell binding domain comprised of both synergy Pro-His-Ser-Arg-Asn (PHSRN) and Arg-Gly-Asp (RGD) sequences.	Glycine	335-338	fibronectin 1	Homo sapiens	116-127
20135634-3	2011	The stabilization of active site residues Asn 303, Gly 324, Ser 329, Cys 331, Asp 364, and Tyr 411 through variable H-bonding coordination from the conserved water molecular center seems interesting in the uninhibited hydrated form of human IMPDH-II structures.	Glycine	51-54	inosine monophosphate dehydrogenase 2	Homo sapiens	241-249
21870221-7	2011	As an alternative approach, we have utilized a glycine-to-serine mutation in the switch 1 region of Galpha subunits that prevents RGS binding.	Glycine	47-54	paired like homeodomain 2	Homo sapiens	130-133
20939853-8	2011	Preoperative glycine injection significantly reduced the induction of interleukin-6 (IL-6), tumor necrosis factor-alpha, inducible nitric oxide synthase and intercellular adhesion molecule-1 mRNAs, which was associated with the attenuation in postoperative leukocyte recruitment.	Glycine	13-20	interleukin 6	Homo sapiens	70-83
20939853-8	2011	Preoperative glycine injection significantly reduced the induction of interleukin-6 (IL-6), tumor necrosis factor-alpha, inducible nitric oxide synthase and intercellular adhesion molecule-1 mRNAs, which was associated with the attenuation in postoperative leukocyte recruitment.	Glycine	13-20	interleukin 6	Homo sapiens	85-89
20939853-8	2011	Preoperative glycine injection significantly reduced the induction of interleukin-6 (IL-6), tumor necrosis factor-alpha, inducible nitric oxide synthase and intercellular adhesion molecule-1 mRNAs, which was associated with the attenuation in postoperative leukocyte recruitment.	Glycine	13-20	tumor necrosis factor	Homo sapiens	92-119
20939853-10	2011	The secretion of the inflammatory proteins IL-6, monocyte chemotactic protein-1/chemokine ligand 2 and macrophage inflammatory protein-1alpha/chemokine ligand 3 were also significantly decreased by glycine pretreatment.	Glycine	198-205	interleukin 6	Homo sapiens	43-47
20810618-1	2010	NR1/NR2A is a subtype of N-methyl-d-aspartate receptors (NMDARs), which are glutamate and glycine-gated Ca(2+)-permeable channels highly expressed in the central nervous system.	Glycine	90-97	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-3
20929265-5	2010	2a-d did not induce inward currents, indicating that they are not transported, but the stereoisomers with an L-configuration at the N-terminal valine (2a and 2b) potently inhibited transport of the hPEPT1 substrate glycylsarcosine (Gly-Sar).	Glycine	232-235	solute carrier family 15 member 1	Homo sapiens	198-204
20726987-6	2010	KEY RESULTS: Ibuprofen concentration dependently inhibited hPEPT1-mediated uptake of Gly-Sar in MDCK/hPEPT1 cells (K(i)(app) = 0.4 mM) but uptake of ibuprofen in Caco-2 cells and MDCK/hPEPT1 cells was not inhibited by hPEPT1 substrates.	Glycine	85-88	solute carrier family 15 member 1	Homo sapiens	59-65
20726987-6	2010	KEY RESULTS: Ibuprofen concentration dependently inhibited hPEPT1-mediated uptake of Gly-Sar in MDCK/hPEPT1 cells (K(i)(app) = 0.4 mM) but uptake of ibuprofen in Caco-2 cells and MDCK/hPEPT1 cells was not inhibited by hPEPT1 substrates.	Glycine	85-88	solute carrier family 15 member 1	Homo sapiens	101-107
20726987-6	2010	KEY RESULTS: Ibuprofen concentration dependently inhibited hPEPT1-mediated uptake of Gly-Sar in MDCK/hPEPT1 cells (K(i)(app) = 0.4 mM) but uptake of ibuprofen in Caco-2 cells and MDCK/hPEPT1 cells was not inhibited by hPEPT1 substrates.	Glycine	85-88	solute carrier family 15 member 1	Homo sapiens	101-107
20726987-6	2010	KEY RESULTS: Ibuprofen concentration dependently inhibited hPEPT1-mediated uptake of Gly-Sar in MDCK/hPEPT1 cells (K(i)(app) = 0.4 mM) but uptake of ibuprofen in Caco-2 cells and MDCK/hPEPT1 cells was not inhibited by hPEPT1 substrates.	Glycine	85-88	solute carrier family 15 member 1	Homo sapiens	101-107
21219031-3	2010	Albumin nanoparticles conjugated with a truncated fragment of fibronectin containing the Arg-Gly-Asp domain were successfully patterned and used as templates to elicit adhesion and spreading of human mesenchymal stem cells and fibroblasts.	Glycine	93-96	fibronectin 1	Homo sapiens	62-73
20810618-1	2010	NR1/NR2A is a subtype of N-methyl-d-aspartate receptors (NMDARs), which are glutamate and glycine-gated Ca(2+)-permeable channels highly expressed in the central nervous system.	Glycine	90-97	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	4-8
20810618-4	2010	Addition of 1 mM glycine, but not 1 mM l-glutamate, was able to surmount compound 1 and 13 inhibitory effects in FLIPR NR1/NR2A assay.	Glycine	17-24	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	119-122
20810618-4	2010	Addition of 1 mM glycine, but not 1 mM l-glutamate, was able to surmount compound 1 and 13 inhibitory effects in FLIPR NR1/NR2A assay.	Glycine	17-24	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	123-127
20678516-3	2010	As glycine is an obligatory co-agonist at the NR1 subunit of the NMDA receptor, blockade of glycine uptake at the glycine transporter type-1 (GlyT1) can enhance low glutamatergic tone.	Glycine	3-10	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	46-49
20881039-8	2010	The sizes of the tryptic phosphopeptides derived from Nup62 were compatible with sites in the Phe/Gly repeat domain which display common consensus sequences for ERK and p38 substrates.	Glycine	98-101	mitogen-activated protein kinase 1	Homo sapiens	161-164
20881039-8	2010	The sizes of the tryptic phosphopeptides derived from Nup62 were compatible with sites in the Phe/Gly repeat domain which display common consensus sequences for ERK and p38 substrates.	Glycine	98-101	mitogen-activated protein kinase 14	Homo sapiens	169-172
20678516-3	2010	As glycine is an obligatory co-agonist at the NR1 subunit of the NMDA receptor, blockade of glycine uptake at the glycine transporter type-1 (GlyT1) can enhance low glutamatergic tone.	Glycine	3-10	solute carrier family 6 member 9	Homo sapiens	142-147
20678516-3	2010	As glycine is an obligatory co-agonist at the NR1 subunit of the NMDA receptor, blockade of glycine uptake at the glycine transporter type-1 (GlyT1) can enhance low glutamatergic tone.	Glycine	92-99	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	46-49
20678516-3	2010	As glycine is an obligatory co-agonist at the NR1 subunit of the NMDA receptor, blockade of glycine uptake at the glycine transporter type-1 (GlyT1) can enhance low glutamatergic tone.	Glycine	92-99	solute carrier family 6 member 9	Homo sapiens	114-140
20678516-3	2010	As glycine is an obligatory co-agonist at the NR1 subunit of the NMDA receptor, blockade of glycine uptake at the glycine transporter type-1 (GlyT1) can enhance low glutamatergic tone.	Glycine	92-99	solute carrier family 6 member 9	Homo sapiens	142-147
20678516-8	2010	GlyT1 inhibitors blocked [(3)H]-glycine uptake in cells expressing the human transporter; other compounds had little or no activity.	Glycine	32-39	solute carrier family 6 member 9	Homo sapiens	0-5
20815824-7	2010	Substitution of the amino acids in position 1, 3 or 5 from the C-terminus with glycine resulted in DegP-dependent degradation of YadA.	Glycine	79-86	Adhesin	Yersinia enterocolitica	129-133
20541608-2	2010	FMRP has two types of RNA binding domains, two K-homology domains and an arginine-glycine-glycine box domain, and it is proposed to act as a translation regulator of specific messenger RNA.	Glycine	82-89	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
20541608-2	2010	FMRP has two types of RNA binding domains, two K-homology domains and an arginine-glycine-glycine box domain, and it is proposed to act as a translation regulator of specific messenger RNA.	Glycine	90-97	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	156-163	fragile X messenger ribonucleoprotein 1	Homo sapiens	24-28
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	156-163	fragile X messenger ribonucleoprotein 1	Homo sapiens	142-146
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	156-163	fragile X messenger ribonucleoprotein 1	Homo sapiens	142-146
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	164-171	fragile X messenger ribonucleoprotein 1	Homo sapiens	24-28
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	164-171	fragile X messenger ribonucleoprotein 1	Homo sapiens	142-146
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	164-171	fragile X messenger ribonucleoprotein 1	Homo sapiens	142-146
20797874-5	2010	The use of excipient exchange to and from one concentration of mannitol to another or to a mixture of glycine and mannitol was reproducibly demonstrated for recombinant human growth hormone (rhGH).	Glycine	102-109	growth hormone 1	Homo sapiens	175-189
20805357-5	2010	Moreover, HCF-1 interacts with the middle region of YY1 encompassing the glycine-lysine-rich domain and is essential for the formation of a ternary complex with YY1 and BAP1 in vivo.	Glycine	73-80	YY1 transcription factor	Homo sapiens	52-55
20943251-8	2010	Meanwhile, the DBPFP yield increased from 3 for glycine to 51mug DBP mg(-1) C for its degradation residue, and from 1 for glucose and starch to 87 and 38mug DBP mg(-1) C for their organic residues, respectively.	Glycine	48-55	D-box binding PAR bZIP transcription factor	Homo sapiens	15-18
20958962-8	2010	Ca2+ permeability could be rescued by mutating the NR3 N site glycine to the NR1-like asparagine.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	77-80
20890276-2	2010	Two glycine-binding NR1 subunits and two glutamate-binding NR2 subunits each form highly Ca2(+)-permeable cation channels which are blocked by extracellular Mg2(+) in a voltage-dependent manner.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	20-23
20691713-11	2010	All GlyT-1 inhibitors tested, as well as glycine itself, competed fully for the binding of both [(3)H]-SB-733993 and [(3)H]-GSK931145 in both hGlyT-1 and rat cortex membranes.	Glycine	41-48	solute carrier family 6 member 9	Homo sapiens	142-149
21061495-2	2004	Ligands such as vitronectin, fibronectin, etc., which interact with integrins, are known to bind these receptors through an Arg-Gly-Asp (RGD) epitope.	Glycine	128-131	fibronectin 1	Homo sapiens	29-40
21055617-0	2010	Technetium-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptides for human melanoma imaging.	Glycine	27-30	proopiomelanocortin	Homo sapiens	46-82
21055617-1	2010	INTRODUCTION: The purpose of this study was to examine whether (99m)Tc-labeled Arg-Gly-Asp (RGD)-conjugated alpha-melanocyte stimulating hormone (alpha-MSH) hybrid peptide targeting both melanocortin-1 (MC1) and alpha(v)beta(3) integrin receptors was superior in melanoma targeting to (99m)Tc-labeled alpha-MSH or RGD peptide targeting only the MC1 or alpha(v)beta(3) integrin receptor.	Glycine	83-86	proopiomelanocortin	Homo sapiens	108-144
21055617-1	2010	INTRODUCTION: The purpose of this study was to examine whether (99m)Tc-labeled Arg-Gly-Asp (RGD)-conjugated alpha-melanocyte stimulating hormone (alpha-MSH) hybrid peptide targeting both melanocortin-1 (MC1) and alpha(v)beta(3) integrin receptors was superior in melanoma targeting to (99m)Tc-labeled alpha-MSH or RGD peptide targeting only the MC1 or alpha(v)beta(3) integrin receptor.	Glycine	83-86	proopiomelanocortin	Homo sapiens	146-155
21055617-1	2010	INTRODUCTION: The purpose of this study was to examine whether (99m)Tc-labeled Arg-Gly-Asp (RGD)-conjugated alpha-melanocyte stimulating hormone (alpha-MSH) hybrid peptide targeting both melanocortin-1 (MC1) and alpha(v)beta(3) integrin receptors was superior in melanoma targeting to (99m)Tc-labeled alpha-MSH or RGD peptide targeting only the MC1 or alpha(v)beta(3) integrin receptor.	Glycine	83-86	proopiomelanocortin	Homo sapiens	301-310
20958962-10	2010	Conversely, "conventional" receptors assembled from NR1 and NR2 could be made Mg2+ insensitive and Ca2+ impermeable by equipping either subunit with the NR3-like glycine at their N positions, with a stronger contribution of the NR1 subunit.	Glycine	162-169	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	52-55
20958962-10	2010	Conversely, "conventional" receptors assembled from NR1 and NR2 could be made Mg2+ insensitive and Ca2+ impermeable by equipping either subunit with the NR3-like glycine at their N positions, with a stronger contribution of the NR1 subunit.	Glycine	162-169	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	228-231
20679349-6	2010	Alanine substitution for Tyr-198, Leu-199, or Val-204 abrogates the ability of p67(phox) to support superoxide production by gp91(phox)-based oxidase as well as its related oxidases Nox1 and Nox3; the activation also involves other invariant residues such as Leu-193, Asp-197, and Gly-200.	Glycine	281-284	CD33 molecule	Homo sapiens	79-82
20679349-6	2010	Alanine substitution for Tyr-198, Leu-199, or Val-204 abrogates the ability of p67(phox) to support superoxide production by gp91(phox)-based oxidase as well as its related oxidases Nox1 and Nox3; the activation also involves other invariant residues such as Leu-193, Asp-197, and Gly-200.	Glycine	281-284	CD33 molecule	Homo sapiens	83-87
20679349-6	2010	Alanine substitution for Tyr-198, Leu-199, or Val-204 abrogates the ability of p67(phox) to support superoxide production by gp91(phox)-based oxidase as well as its related oxidases Nox1 and Nox3; the activation also involves other invariant residues such as Leu-193, Asp-197, and Gly-200.	Glycine	281-284	CD33 molecule	Homo sapiens	130-134
19864106-0	2010	Glycine regulates inflammatory markers modifying the energetic balance through PPAR and UCP-2.	Glycine	0-7	peroxisome proliferator activated receptor alpha	Mus musculus	79-83
20724821-3	2010	One of them requires the participation of Atg8 synthesized as a precursor protein, which is cleaved after a Gly residue by a cysteine proteinase called Atg4.	Glycine	108-111	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	42-46
20724821-3	2010	One of them requires the participation of Atg8 synthesized as a precursor protein, which is cleaved after a Gly residue by a cysteine proteinase called Atg4.	Glycine	108-111	cysteine protease ATG4	Saccharomyces cerevisiae S288C	152-156
20724821-4	2010	The new Gly-terminal residue from Atg8 is activated by Atg7 (an E1-like enzyme) then transferred to Atg3 (an E2-like enzyme) and finally conjugated with membrane-bound phosphatidylethanolamine (PE) through an amide bond.	Glycine	8-11	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	34-38
20724821-4	2010	The new Gly-terminal residue from Atg8 is activated by Atg7 (an E1-like enzyme) then transferred to Atg3 (an E2-like enzyme) and finally conjugated with membrane-bound phosphatidylethanolamine (PE) through an amide bond.	Glycine	8-11	Atg7p	Saccharomyces cerevisiae S288C	55-59
19864106-0	2010	Glycine regulates inflammatory markers modifying the energetic balance through PPAR and UCP-2.	Glycine	0-7	uncoupling protein 2 (mitochondrial, proton carrier)	Mus musculus	88-93
19864106-6	2010	Recently, glycine has been reported to have anti-inflammatory properties which reduce TNF-alpha and IL-6 levels and increase adiponectin in 3T3-L1 adipocytes and in fat tissue of obese mice.	Glycine	10-17	tumor necrosis factor	Mus musculus	86-95
19864106-6	2010	Recently, glycine has been reported to have anti-inflammatory properties which reduce TNF-alpha and IL-6 levels and increase adiponectin in 3T3-L1 adipocytes and in fat tissue of obese mice.	Glycine	10-17	interleukin 6	Mus musculus	100-104
19864106-10	2010	Interestingly, glycine treatment also suppressed the expression of UCP-2, TNF-alpha and IL-6 in lean mice, and increased adiponectin and insulin serum levels.	Glycine	15-22	uncoupling protein 2 (mitochondrial, proton carrier)	Mus musculus	67-72
19864106-10	2010	Interestingly, glycine treatment also suppressed the expression of UCP-2, TNF-alpha and IL-6 in lean mice, and increased adiponectin and insulin serum levels.	Glycine	15-22	tumor necrosis factor	Mus musculus	74-83
19864106-10	2010	Interestingly, glycine treatment also suppressed the expression of UCP-2, TNF-alpha and IL-6 in lean mice, and increased adiponectin and insulin serum levels.	Glycine	15-22	interleukin 6	Mus musculus	88-92
20880398-8	2010	In Caco-2 cell monolayers, the apical uptake of 30 mM Gly-Sar was inhibited by 20 and 22% in the presence of 5-HTP or Bip-Pro, respectively, and by 48% in the presence of both.	Glycine	54-57	heat shock protein family A (Hsp70) member 5	Homo sapiens	118-121
20973643-7	2010	Gln-Gly cleavages are largely associated with PRP classes, while Tyr-Gly cleavages are related to histatin 1 and to the P-B peptide.	Glycine	4-7	prion protein	Homo sapiens	46-49
20731414-8	2010	The main and primary cleavage sites were located in the N-terminal half of statherin, specifically after Arg(9), Arg(10), and Arg(13); after Phe(14) and Tyr(18); and after Gly(12), Gly(15), Gly(17) and Gly(19) while the C-terminal half of statherin remained intact.	Glycine	172-175	statherin	Homo sapiens	75-84
20731414-8	2010	The main and primary cleavage sites were located in the N-terminal half of statherin, specifically after Arg(9), Arg(10), and Arg(13); after Phe(14) and Tyr(18); and after Gly(12), Gly(15), Gly(17) and Gly(19) while the C-terminal half of statherin remained intact.	Glycine	181-184	statherin	Homo sapiens	75-84
20731414-8	2010	The main and primary cleavage sites were located in the N-terminal half of statherin, specifically after Arg(9), Arg(10), and Arg(13); after Phe(14) and Tyr(18); and after Gly(12), Gly(15), Gly(17) and Gly(19) while the C-terminal half of statherin remained intact.	Glycine	181-184	statherin	Homo sapiens	75-84
20731414-8	2010	The main and primary cleavage sites were located in the N-terminal half of statherin, specifically after Arg(9), Arg(10), and Arg(13); after Phe(14) and Tyr(18); and after Gly(12), Gly(15), Gly(17) and Gly(19) while the C-terminal half of statherin remained intact.	Glycine	181-184	statherin	Homo sapiens	75-84
20850334-1	2010	Among the three zinc finger-containing glycine-rich RNA-binding proteins, named AtRZ-1a, AtRZ-1b, and AtRZ-1c, in the Arabidopsis thaliana genome, AtRZ-1a has previously been shown to enhance cold and freezing tolerance in Arabidopsis.	Glycine	39-46	RNA-binding (RRM/RBD/RNP motifs) family protein with retrovirus zinc finger-like domain-containing protein	Arabidopsis thaliana	102-109
20542070-1	2010	Glycine transporter GlyT1 plays important role in maintaining accurate glycine concentration in local brain microenvironment.	Glycine	71-78	solute carrier family 6 member 9	Homo sapiens	20-25
20623529-4	2010	We demonstrate that glycine does not affect the production of reactive oxygen species but stimulates myelin phagocytosis and the production of the proinflammatory mediators nitric oxide (NO) and tumor necrosis factor (TNF)-alpha by rat macrophages.	Glycine	20-27	tumor necrosis factor	Rattus norvegicus	195-228
20449699-8	2010	Affinities for hPEPT1 of relevant tripeptides were determined by competition studies with [14C]Gly-Sar in MDCK/hPEPT1 cells.	Glycine	95-98	solute carrier family 15 member 1	Homo sapiens	15-21
20541619-2	2010	FUS/TLS belongs to a sub-family of RNA binding proteins, encoding an N-terminal serine-tyrosine-glycine-glutamine (SYGQ) region, an RNA recognition motif (RRM) flanked by glycine rich (G-rich) regions, a cysteine(2)/cysteine(2) zinc finger motif and multiple RGG repeats.	Glycine	96-103	FUS RNA binding protein	Homo sapiens	0-7
20541619-2	2010	FUS/TLS belongs to a sub-family of RNA binding proteins, encoding an N-terminal serine-tyrosine-glycine-glutamine (SYGQ) region, an RNA recognition motif (RRM) flanked by glycine rich (G-rich) regions, a cysteine(2)/cysteine(2) zinc finger motif and multiple RGG repeats.	Glycine	171-178	FUS RNA binding protein	Homo sapiens	0-7
19824051-8	2010	Structure-activity studies on Gly(5) enabled identification of the first generation of peptidergic NPSR pure antagonists including [D-Cys(tBu)(5)]NPS and [D-Val(5)]NPS whose antagonist properties were confirmed in vivo.	Glycine	30-33	neuropeptide S receptor 1	Homo sapiens	99-103
20844142-3	2010	Within the glutamate receptor family, NMDA-sensitive channels are unique in their requirement that both glycine and glutamate bind to homologous regions on GluN1 and GluN2 subunits, respectively, before the channel can open.	Glycine	104-111	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	156-161
20558765-6	2010	We found that uptake of glycine-sarcosine, a specific substrate of PepT1, in intestinal epithelial Caco2-BBE cells was inhibited by Tri-DAP in a dose-dependent manner.	Glycine	24-31	solute carrier family 15 member 1	Homo sapiens	67-72
20571078-10	2010	Moreover, [d-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO) treatment increased both reporter promoter activity and Sult4a1 levels in mu-opioid receptor expressing Neuro2a/mu-opioid receptor cells, and EMSAs showed this to be due to increased binding of CREB and ATF-2 to the Sult4a1 promoter.	Glycine	31-34	cAMP responsive element binding protein 1	Mus musculus	254-258
20571078-10	2010	Moreover, [d-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO) treatment increased both reporter promoter activity and Sult4a1 levels in mu-opioid receptor expressing Neuro2a/mu-opioid receptor cells, and EMSAs showed this to be due to increased binding of CREB and ATF-2 to the Sult4a1 promoter.	Glycine	31-34	activating transcription factor 2	Mus musculus	263-268
20623529-6	2010	In contrast, 2-aminoisobutyric acid, a substrate of neutral amino acid transporters (NAATs), inhibits the glycine-mediated enhancement of myelin phagocytosis as well as of NO and TNF-alpha production.	Glycine	106-113	tumor necrosis factor	Homo sapiens	179-188
20305126-4	2010	Here we report on the characterization of human glycine N-acyltransferase-like 2 (hGLYATL2), a member of a gene family of 4 putative glycine conjugating enzymes, and show that it synthesizes various N-acyl glycines.	Glycine	48-55	glycine-N-acyltransferase like 2	Homo sapiens	82-90
20305126-5	2010	Recombinantly expressed hGLYATL2 efficiently conjugated oleoyl-CoA, arachidonoyl-CoA, and other medium- and long-chain acyl-CoAs to glycine.	Glycine	132-139	glycine-N-acyltransferase like 2	Homo sapiens	24-32
20513439-7	2010	To confirm that Erk indeed catalyzes phosphorylation of PKCalpha at T(638), we used a mutant Erk construct in which a relatively large amino acid residue in the ATP binding site (Q(103)) had been replaced with glycine, enabling this mutant to utilize a bulky analog of ATP, cyclopentyl ATP.	Glycine	210-217	mitogen-activated protein kinase 1	Mus musculus	16-19
20522590-6	2010	Among Pima Indians with normal glucose tolerance, the diabetes risk allele glycine of Gly54Asp was associated with a decreased acute insulin response to an intravenous glucose bolus infusion (P = 0.004, adjusted for age, sex, percent body fat, glucose disposal under physiological insulin stimulation, and family membership).	Glycine	75-82	insulin	Homo sapiens	133-140
20448042-4	2010	The N-methyl-D-aspartate (NMDA) receptor is composed of NR1 and NR2 subunits, which are activated by co-agonist glycine and glutamate or aspartate, respectively.	Glycine	112-119	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	56-59
20448042-8	2010	Pharmacological and molecular inhibition of DVC NR1 negated the metabolic effect of glycine.	Glycine	84-91	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	48-51
20471394-5	2010	The ErbB1 and ErbB2 TM domains associate in a right-handed alpha-helical bundle through their N-terminal double GG4-like motif T(648)G(649)X(2)G(652)A(653) and glycine zipper motif T(652)X(3)S(656)X(3)G(660), respectively.	Glycine	160-167	epidermal growth factor receptor	Homo sapiens	4-9
20471394-5	2010	The ErbB1 and ErbB2 TM domains associate in a right-handed alpha-helical bundle through their N-terminal double GG4-like motif T(648)G(649)X(2)G(652)A(653) and glycine zipper motif T(652)X(3)S(656)X(3)G(660), respectively.	Glycine	160-167	erb-b2 receptor tyrosine kinase 2	Homo sapiens	14-19
20513439-7	2010	To confirm that Erk indeed catalyzes phosphorylation of PKCalpha at T(638), we used a mutant Erk construct in which a relatively large amino acid residue in the ATP binding site (Q(103)) had been replaced with glycine, enabling this mutant to utilize a bulky analog of ATP, cyclopentyl ATP.	Glycine	210-217	protein kinase C, alpha	Mus musculus	56-64
20453144-10	2010	Measurement of beta-galactosidase activity of a USDA257 strain containing a transcriptional fusion of gcvT promoter sequences to the lacZ gene revealed that the USDA257 gcvTHP operon was inducible by glycine.	Glycine	200-207	beta-galactosidase	Glycine max	15-33
20471369-0	2010	Screening of novel dominant negative mutant actins using glycine targeted scanning identifies G146V actin that cooperatively inhibits cofilin binding.	Glycine	57-64	actin	Saccharomyces cerevisiae S288C	44-49
20399914-0	2010	Biochemical and structural consequences of a glycine deletion in the alpha-8 helix of protoporphyrinogen oxidase.	Glycine	45-52	protoporphyrinogen oxidase, chloroplastic	Nicotiana tabacum	86-112
20385709-3	2010	BK-induced phosphorylation of extracellular signal-regulated protein kinase (ERK) in mIMCD-3 cells was reduced by approximately 65% by synthetic peptides containing an Arg-Gly-Asp sequence, supporting roles for integrins in BK-induced signaling.	Glycine	172-175	mitogen-activated protein kinase 1	Mus musculus	30-75
20385709-3	2010	BK-induced phosphorylation of extracellular signal-regulated protein kinase (ERK) in mIMCD-3 cells was reduced by approximately 65% by synthetic peptides containing an Arg-Gly-Asp sequence, supporting roles for integrins in BK-induced signaling.	Glycine	172-175	mitogen-activated protein kinase 1	Mus musculus	77-80
20562868-3	2010	We found that an aspartate to glycine substitution in the C(2)F domain of the synaptic vesicle protein otoferlin impaired hearing by reducing vesicle replenishment in the pachanga mouse model of human deafness DFNB9.	Glycine	30-37	otoferlin	Mus musculus	103-112
20307658-3	2010	Growth of AsPC-1 cells was inhibited by these two peptides and a typical PEPT1/SLC15A1 substrate Gly-Sar.	Glycine	97-100	solute carrier family 15 member 1	Homo sapiens	73-78
20307658-3	2010	Growth of AsPC-1 cells was inhibited by these two peptides and a typical PEPT1/SLC15A1 substrate Gly-Sar.	Glycine	97-100	solute carrier family 15 member 1	Homo sapiens	79-86
20307658-4	2010	Growth inhibition by Gly-Sar, Phe-Sar and Bip(OMe)-Sar was concentration-dependent with half-maximal inhibitory concentration of 50, 0.91 and 0.55mM, respectively.	Glycine	21-24	heat shock protein family A (Hsp70) member 5	Homo sapiens	42-45
20195697-1	2010	Over the past years, accumulating evidence has indicated that D-serine is the endogenous ligand for the glycine-modulatory binding site on the NR1 subunit of N-methyl-D-aspartate receptors in various brain areas.	Glycine	104-111	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	143-146
21055228-8	2010	CONCLUSIONS: Free bile acids (CA, DCA and CDCA) can inhibit the expression of IL-6 and the cell viability, while glycine conjugates (GCA, GDCA and GCDCA) can promote the expression of IL-6 and the cell viability.	Glycine	113-120	interleukin 6	Homo sapiens	184-188
20471369-3	2010	A series of mutant actin genes in which glycine residues in actin were systematically substituted by valine residues were constructed, and were expressed individually in yeast cells that carry a wild-type endogenous actin gene.	Glycine	40-47	actin	Saccharomyces cerevisiae S288C	19-24
20471369-3	2010	A series of mutant actin genes in which glycine residues in actin were systematically substituted by valine residues were constructed, and were expressed individually in yeast cells that carry a wild-type endogenous actin gene.	Glycine	40-47	actin	Saccharomyces cerevisiae S288C	60-65
20471369-3	2010	A series of mutant actin genes in which glycine residues in actin were systematically substituted by valine residues were constructed, and were expressed individually in yeast cells that carry a wild-type endogenous actin gene.	Glycine	40-47	actin	Saccharomyces cerevisiae S288C	60-65
20392700-5	2010	In the C-telopeptide region of the alpha1 chain, pepsin cleaved between Asp(1035) and Phe(1036), and actinidain between Gly(1032) and Gly(1033).	Glycine	120-123	asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)	Gallus gallus	35-41
20382160-4	2010	Sequence alignment revealed a new enzyme-specific conserved amino acid close to the active site: methionine (position 144 in human enzyme) in prRDH and glycine (position 145) in 17beta-HSD1.	Glycine	152-159	hydroxysteroid 17-beta dehydrogenase 1	Homo sapiens	178-189
20382160-7	2010	Changing of the prRDH-specific methionine to glycine resulted in a gain of function: the mutants now catalyzed the reduction of estrone and all-trans retinal.	Glycine	45-52	retinol dehydrogenase 8	Homo sapiens	16-21
20392700-5	2010	In the C-telopeptide region of the alpha1 chain, pepsin cleaved between Asp(1035) and Phe(1036), and actinidain between Gly(1032) and Gly(1033).	Glycine	134-137	asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)	Gallus gallus	35-41
20392700-6	2010	Thus, the actinidain-hydrolyzed alpha1 chain is shorter at the C terminus by three residues, Gly(1033), Phe(1034), and Asp(1035).	Glycine	93-96	asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)	Gallus gallus	32-38
20513056-2	2010	Cyclodiene resistance in many insects is associated with replacement of a single amino acid (alanine at position 302) with either a serine or a glycine in the Rdl gene.	Glycine	144-151	Resistant to dieldrin	Drosophila melanogaster	159-162
20642005-12	2004	A lactam bridge-cyclized alpha-MSH analog, GlyGlu-c[Lys-Nlc-Glu-His-d-Phe-Arg-Trp-Gly-Arg-Pro-Val-Asp] (GlyGlu-CycMSH), was conjugated with DOTA (11).	Glycine	43-46	proopiomelanocortin	Homo sapiens	25-34
20333677-11	2010	Bcl-2/Bax ratio was significantly higher with the antagonist, suggested that the glycine site-specific NMDA receptor antagonist protecting RGC death might through inhibition of apoptotic signaling.	Glycine	81-88	BCL2, apoptosis regulator	Rattus norvegicus	0-5
19768790-4	2010	The presence of a small molecule that inhibits autophosphorylation of the FGF2 receptor blocked the effects of FGF2 on hMSC viability in PEG hydrogels, both in the presence and absence of the Arg-Gly-Asp-Ser-Pro (RGDSP) ligand.	Glycine	196-199	fibroblast growth factor 2	Homo sapiens	74-78
20193774-6	2010	For TAP1-637, Asp/Gly heterozygosity was significantly more prevalent in CE patients than in controls (20 vs. 4%, odds ratio 6.0), while Gly/Gly homozygosity was less frequent (5 vs. 14%).	Glycine	18-21	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	4-8
20150244-10	2010	Pat-1 interacts with carbonic anhydrase II (CAII), and studies using CAII(-) intestine or the pharmacological inhibitor methazolamide on WT intestine resulted in increased epithelial acidification during Gly-Sar exposure.	Glycine	204-207	carbonic anhydrase 2	Mus musculus	69-73
20642000-4	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
20495767-3	2010	Previous studies have shown that catalase binds to A-beta fibrils and appears to recognize a region containing the Gly-Ala-Ile-Ile sequence that is similar to the Gly-Ala-Ile-Leu sequence found in human IAPP residues 24-27.	Glycine	115-118	catalase	Homo sapiens	33-41
20495767-3	2010	Previous studies have shown that catalase binds to A-beta fibrils and appears to recognize a region containing the Gly-Ala-Ile-Ile sequence that is similar to the Gly-Ala-Ile-Leu sequence found in human IAPP residues 24-27.	Glycine	163-166	catalase	Homo sapiens	33-41
20495767-10	2010	For IAPP 1-37 and 8-37, the catalase binding was primarily directed towards fibrillar rather than ribbon-like structures, suggesting differences in the accessibility of the human IAPP 24-27 Gly-Ala-Ile-Leu region.	Glycine	190-193	catalase	Homo sapiens	28-36
20236938-5	2010	The acidic P3 residue of PAR1, Asp(39), does not hinder binding to the active site and actually makes favorable interactions with Gly(219) of thrombin.	Glycine	130-133	coagulation factor II thrombin receptor	Homo sapiens	25-29
20236938-5	2010	The acidic P3 residue of PAR1, Asp(39), does not hinder binding to the active site and actually makes favorable interactions with Gly(219) of thrombin.	Glycine	130-133	coagulation factor II, thrombin	Homo sapiens	142-150
21253021-3	2010	One means of enhancing NMDA receptor neurotransmission is to increase the availability of the obligatory co-agonist glycine at modulatory sites on the NMDA receptors through the inhibition of glycine transporter-1 (GlyT-1) on glial cells.	Glycine	116-123	solute carrier family 6 member 9	Homo sapiens	192-213
21253021-3	2010	One means of enhancing NMDA receptor neurotransmission is to increase the availability of the obligatory co-agonist glycine at modulatory sites on the NMDA receptors through the inhibition of glycine transporter-1 (GlyT-1) on glial cells.	Glycine	116-123	solute carrier family 6 member 9	Homo sapiens	215-221
20304927-2	2010	Typically, glycine binding NR1 subunits co-assemble with glutamate binding NR2 subunits to form a functional receptor.	Glycine	11-18	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	27-30
20131279-5	2010	Sequencing of COL2A1 in the propositi revealed 2 sequence changes resulting in glycine substitutions in the triple-helical domain of type II collagen.	Glycine	79-86	collagen type II alpha 1 chain	Homo sapiens	14-20
20382967-11	2010	CONCLUSIONS: The glycine residue at amino acid 773 of ClpC1 is essential for its functions.	Glycine	17-24	CLPC homologue 1	Arabidopsis thaliana	54-59
20412299-8	2010	Structural comparison with the nNOS-DYNLL1 complex reveals that a glycine residue of GRINL1A occupies the conserved glutamine site within the DYNLL1 binding groove.	Glycine	66-73	dynein light chain LC8-type 1	Homo sapiens	36-42
20356736-2	2010	SAR studies indicate that different substituents on the aryloxazole/thiazole moieties as well as the choice of carbamate substituent on the glycine moiety can significantly modulate the selectivity of PPARalpha versus PPARgamma.	Glycine	140-147	peroxisome proliferator activated receptor gamma	Homo sapiens	218-227
20218897-5	2010	Two missense mutations in UTF1 are reported: rs11599284, which results in a glycine to an arginine change at amino acid 73, and rs4480453, resulting in a leucine to methionine change at amino acid 275.	Glycine	76-83	undifferentiated embryonic cell transcription factor 1	Homo sapiens	26-30
20404487-5	2010	First, we showed that GABARAPL1 is cleaved at glycine 116, a residue which is conserved in other members of the family.	Glycine	46-53	GABA type A receptor associated protein like 1	Homo sapiens	22-31
20412299-8	2010	Structural comparison with the nNOS-DYNLL1 complex reveals that a glycine residue of GRINL1A occupies the conserved glutamine site within the DYNLL1 binding groove.	Glycine	66-73	dynein light chain LC8-type 1	Homo sapiens	142-148
20237295-11	2010	Finally, LPC induced p38 MAPK phosphorylation in an extracellular calcium/glycine dependent manner.	Glycine	74-81	mitogen-activated protein kinase 14	Homo sapiens	21-24
19656574-6	2010	The androgen receptor (AR) gene has two polymorphic regions in exon I; glutamine encoding CAG and glycine encoding GGN repeats.	Glycine	98-105	androgen receptor	Homo sapiens	4-21
19656574-6	2010	The androgen receptor (AR) gene has two polymorphic regions in exon I; glutamine encoding CAG and glycine encoding GGN repeats.	Glycine	98-105	androgen receptor	Homo sapiens	23-25
19656574-6	2010	The androgen receptor (AR) gene has two polymorphic regions in exon I; glutamine encoding CAG and glycine encoding GGN repeats.	Glycine	98-105	gametogenetin	Homo sapiens	115-118
20197274-6	2010	In this in situ based NBCe1-A topology, residues mutated in pRTA (pRTA residues) are assigned as: Ser(427), TM1; Thr(485) and Gly(486), TM3; Arg(510) and Leu(522), TM4; Ala(799), TM10; and Arg(881), TM12.	Glycine	126-129	solute carrier family 4 member 4	Homo sapiens	22-29
19887019-1	2010	Recent evidence indicates that enhancing N-methyl-D-aspartate (NMDA) neurotransmission with the treatment of NMDA/glycine site agonists, such as D-serine, or a glycine transporter-1 (GlyT-1) antagonist, N-methylglycine (sarcosine), can improve symptoms of schizophrenia.	Glycine	114-121	solute carrier family 6 member 9	Homo sapiens	183-189
20097255-4	2010	While glutamate activates triheteromeric NMDARs composed of NR1/NR2/NR3A subunits, glycine is sufficient to activate diheteromeric NR1/NR3A-containing receptors.	Glycine	83-90	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	131-134
20407581-0	2010	Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca-Dependent Outward Rectification.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	30-33
20646482-1	2010	OBJECTIVE: To explore the therapy effects of (arginine-glycine-aspartic, RGD)(3)-truncated tissue factor (tTF) fusion protein on colorectal carcinoma in mice.	Glycine	55-62	coagulation factor III	Mus musculus	91-104
19932771-6	2010	The catalytic domain of MMP-12 binds to the triple helix and cleaves the typical sites -Gly(775)-Leu(776)- in alpha-2 type I collagen and -Gly(775)-Ile(776)- in alpha-1 type I and type III collagens and at multiple other sites in both collagen types.	Glycine	88-91	collagen type I alpha 2 chain	Homo sapiens	110-133
20107021-5	2010	Like yeast ATG8, CrATG8 is cleaved at the carboxyl-terminal conserved glycine and is associated with membranes in Chlamydomonas.	Glycine	70-77	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	11-15
20407581-3	2010	Classical Ca(2+)-permeable NMDA receptors are composed of glycine-binding NR1 and glutamate-binding NR2 subunits, and hence require both glutamate and glycine for efficient activation.	Glycine	58-65	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	74-77
20407581-3	2010	Classical Ca(2+)-permeable NMDA receptors are composed of glycine-binding NR1 and glutamate-binding NR2 subunits, and hence require both glutamate and glycine for efficient activation.	Glycine	151-158	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	74-77
20407581-4	2010	In contrast, recombinant receptors composed of NR1 and the glycine binding NR3A and/or NR3B subunits lack glutamate binding sites and can be activated by glycine alone.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	47-50
20407581-6	2010	Co-application of antagonists of the NR1 glycine-binding site or of the divalent cation Zn(2+) markedly enhances the glycine responses of these receptors.	Glycine	41-48	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	37-40
20407581-6	2010	Co-application of antagonists of the NR1 glycine-binding site or of the divalent cation Zn(2+) markedly enhances the glycine responses of these receptors.	Glycine	117-124	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	37-40
20407581-8	2010	Whole-cell current-voltage relations of glycine currents recorded from NR1/NR3B and NR1/NR3A/NR3B expressing oocytes were found to be linear under our recording conditions.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	71-74
20407581-8	2010	Whole-cell current-voltage relations of glycine currents recorded from NR1/NR3B and NR1/NR3A/NR3B expressing oocytes were found to be linear under our recording conditions.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	84-87
20123783-0	2010	Glycine transporter GLYT1 is essential for glycine-mediated protection of human intestinal epithelial cells against oxidative damage.	Glycine	43-50	solute carrier family 6 member 9	Homo sapiens	20-25
20123783-3	2010	The objectives of the current study were to demonstrate directly glycine-mediated protection of human intestinal epithelial cells and to determine the requirement for glycine uptake by the specific transporter GLYT1.	Glycine	167-174	solute carrier family 6 member 9	Homo sapiens	210-215
20123783-6	2010	Protection was dependent on GLYT1 activity, being blocked by a specific GLYT1 inhibitor, supporting a requirement for intracellular glycine accumulation.	Glycine	132-139	solute carrier family 6 member 9	Homo sapiens	28-33
20123783-6	2010	Protection was dependent on GLYT1 activity, being blocked by a specific GLYT1 inhibitor, supporting a requirement for intracellular glycine accumulation.	Glycine	132-139	solute carrier family 6 member 9	Homo sapiens	72-77
20045321-2	2010	Synthesis and SAR follow-up of a series of octahydro-cyclopenta[c]pyrrole derivatives afforded potent in vitro inhibition of GlyT1 as well as in vivo activity in elevating CSF glycine.	Glycine	176-183	solute carrier family 6 member 9	Homo sapiens	125-130
20148533-3	2010	Herein we present data obtained from two separate series of thrombin inhibitors containing hydrophobic side chains of increasing size that bind in the S3 pocket and with, or without, an adjacent amine that engages in a hydrogen bond with Gly 216.	Glycine	238-241	coagulation factor II, thrombin	Homo sapiens	60-68
20209060-2	2010	After subcutaneous injection insulin glargine is partly converted into the two main metabolites M1 ([Gly(A21)]insulin) and M2 ([Gly(A21),des-Thr(B30)]insulin).	Glycine	101-104	insulin	Homo sapiens	29-36
20167108-3	2010	TTL is a member of the transthyretin-related protein family (TRP), which comprises a number of proteins with sequence homology to transthyretin (TTR) and the characteristic C-terminal sequence motif Tyr-Arg-Gly-Ser.	Glycine	207-210	coiled coil protein	Arabidopsis thaliana	0-3
19948730-6	2010	Here we show that the MTHFD1L enzyme is present in mitochondria from normal embryonic tissues and embryonic fibroblast cell lines, and embryonic mitochondria possess the ability to synthesize formate from glycine.	Glycine	205-212	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	Mus musculus	22-29
20047279-9	2010	From this library, we found an improved clone, scFv#m2-c4 (K(a) = 6.3 x 10(8) M(-1); Lys(H19)Arg, Tyr(H56)Phe, Ser(H84)Pro, Glu(H85)Gly, Gln(L27)Arg, Leu(L36)Met, Ser(L63)Gly, and Ser(L77)Gly).	Glycine	132-135	immunglobulin heavy chain variable region	Homo sapiens	47-51
20047279-9	2010	From this library, we found an improved clone, scFv#m2-c4 (K(a) = 6.3 x 10(8) M(-1); Lys(H19)Arg, Tyr(H56)Phe, Ser(H84)Pro, Glu(H85)Gly, Gln(L27)Arg, Leu(L36)Met, Ser(L63)Gly, and Ser(L77)Gly).	Glycine	171-174	immunglobulin heavy chain variable region	Homo sapiens	47-51
20047279-9	2010	From this library, we found an improved clone, scFv#m2-c4 (K(a) = 6.3 x 10(8) M(-1); Lys(H19)Arg, Tyr(H56)Phe, Ser(H84)Pro, Glu(H85)Gly, Gln(L27)Arg, Leu(L36)Met, Ser(L63)Gly, and Ser(L77)Gly).	Glycine	171-174	immunglobulin heavy chain variable region	Homo sapiens	47-51
20100277-4	2010	EXPERIMENTAL APPROACH: Residues Lys28, Lys41 and Arg580 in OATP1B3 were substituted by alanine, arginine, glutamine, glycine or lysine.	Glycine	117-124	solute carrier organic anion transporter family member 1B3	Homo sapiens	59-66
20071328-3	2010	Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties.	Glycine	97-100	coagulation factor II, thrombin	Homo sapiens	24-32
20799661-3	2010	Also it was shown that enkephalins, VIP and SS are potent to augment the inhibiting effect of GABA and glycine.	Glycine	103-110	vasoactive intestinal peptide	Felis catus	36-39
20128809-6	2010	KEY RESULTS: ALA inhibited SLC36A1-mediated L-[(3)H]Pro and SLC15A1-mediated [(14)C]Gly-Sar uptake in Caco-2 cell monolayers with IC(50) values of 11.3 and 2.1 mM respectively.	Glycine	84-87	solute carrier family 15 member 1	Homo sapiens	60-67
19898886-1	2010	N-myristoylation is the attachment of a 14-carbon fatty acid, myristate, onto the N-terminal glycine residue of target proteins, catalysed by N-myristoyltransferase (NMT), a ubiquitous and essential enzyme in eukaryotes.	Glycine	93-100	N-myristoyltransferase 1	Homo sapiens	142-164
19898886-1	2010	N-myristoylation is the attachment of a 14-carbon fatty acid, myristate, onto the N-terminal glycine residue of target proteins, catalysed by N-myristoyltransferase (NMT), a ubiquitous and essential enzyme in eukaryotes.	Glycine	93-100	N-myristoyltransferase 1	Homo sapiens	166-169
20164358-1	2010	We have studied relative efficacies of NR1 agonists glycine and d-cycloserine (DCS), and found efficacy to be dependent on the NR2 subunit.	Glycine	52-59	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	39-42
20164358-2	2010	DCS shows partial agonism at NR1/NR2B but has higher relative efficacy than glycine at NR1/NR2C receptor.	Glycine	76-83	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	87-90
19799936-2	2010	Here we examined the effects of a glycine transporter (GlyT1) inhibitor, which elevates glycine and hence NMDA signaling, on the behavioral effects of nicotine.	Glycine	34-41	solute carrier family 6 member 9	Homo sapiens	55-60
20124201-10	2010	While insertions/deletions of 2 glycines (G) were suggested to be pathogenic in the initial FUS reports, we observed an identical GG-deletion in 2 healthy individuals and similar G-insertions/deletions in 4 other control individuals, suggesting that G-insertions/deletions within this G-rich region may be tolerated.	Glycine	32-40	FUS RNA binding protein	Homo sapiens	92-95
20045315-7	2010	An additional hydrogen bond interaction of the piperidine nitrogen to Gly-888 also contributes to the binding affinity of 1e to PARP-1.	Glycine	70-73	poly(ADP-ribose) polymerase 1	Homo sapiens	128-134
20233000-6	2010	RESULTS: Glycine pretreatment markedly decreased transaminase release (AST, 12 hr: glycine 1292 +/- 192 U/L, control 2311 +/- 556 U/L, p &lt; .05; ALT, 12 hr: glycine 1013 +/- 278 U/L, control 2038 +/- 500 U/L, p &lt; .05), serum ALP activity and serum bilirubin levels (p &lt; .05).	Glycine	9-16	solute carrier family 17 member 5	Homo sapiens	71-74
20233000-7	2010	Prothrombin time was reduced, and histologically, liver injury was also decreased in the glycine group.	Glycine	89-96	coagulation factor II, thrombin	Homo sapiens	0-11
19756956-7	2010	These data demonstrate that NEP is myristoylated at Gly-2 and that this modification is an intrinsic signal for membrane targeting.	Glycine	52-55	membrane metalloendopeptidase	Homo sapiens	28-31
19822234-7	2010	Such recognition was mediated via a "second" arginine-glycine-aspartic acid (RGD) sequence that is present in the V95 subsegment in rat, but not human, FN.	Glycine	54-61	fibronectin 1	Homo sapiens	152-154
20714130-4	2010	By multiple linear regression, we found that in healthy people, total Hcy was the most important determinant of LDL-bound Hcy and Cys-Gly was negatively associated with apoB-Hcy concentrations.	Glycine	134-137	apolipoprotein B	Homo sapiens	169-173
19954189-0	2010	Variations at the semiconserved glycine in the IQ domain consensus sequence have a major impact on Ca2+-dependent switching in calmodulin-IQ domain complexes.	Glycine	32-39	calmodulin 1	Homo sapiens	127-137
19954189-1	2010	We have replaced the semiconserved Gly in the IQ domain consensus sequence with Ala, Arg, or Met in a reference sequence and determined how this affects its complexes with calmodulin.	Glycine	35-38	calmodulin 1	Homo sapiens	172-182
20161699-9	2009	GlyT1 mediates rapid uptake of glycine from the synaptic cleft, terminating synaptic transmission.	Glycine	31-38	solute carrier family 6 member 9	Danio rerio	0-5
20166994-7	2010	The biological function of glycine-extended gastrin in synergizing gastrin-17 has been revealed in gastrin knockout mice.	Glycine	27-34	gastrin	Mus musculus	44-51
20166956-3	2010	A key component of cerebral glycine metabolism is the glycine transporter type 1 (GlyT1) and elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders.	Glycine	28-35	solute carrier family 6 member 9	Homo sapiens	54-80
20166994-7	2010	The biological function of glycine-extended gastrin in synergizing gastrin-17 has been revealed in gastrin knockout mice.	Glycine	27-34	gastrin	Mus musculus	67-74
20166956-3	2010	A key component of cerebral glycine metabolism is the glycine transporter type 1 (GlyT1) and elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders.	Glycine	28-35	solute carrier family 6 member 9	Homo sapiens	82-87
20166956-3	2010	A key component of cerebral glycine metabolism is the glycine transporter type 1 (GlyT1) and elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders.	Glycine	28-35	solute carrier family 6 member 9	Homo sapiens	166-171
20166994-7	2010	The biological function of glycine-extended gastrin in synergizing gastrin-17 has been revealed in gastrin knockout mice.	Glycine	27-34	gastrin	Mus musculus	67-74
20166956-3	2010	A key component of cerebral glycine metabolism is the glycine transporter type 1 (GlyT1) and elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders.	Glycine	54-61	solute carrier family 6 member 9	Homo sapiens	82-87
20130411-6	2010	PCOS patients who had the Ser/Ser genotype of the PGC-1alpha Gly482Ser polymorphism had significantly higher levels of postprandial 2-hour insulin than those with the Gly/Ser genotype (p = 0.045).	Glycine	61-64	PPARG coactivator 1 alpha	Homo sapiens	50-60
20130411-6	2010	PCOS patients who had the Ser/Ser genotype of the PGC-1alpha Gly482Ser polymorphism had significantly higher levels of postprandial 2-hour insulin than those with the Gly/Ser genotype (p = 0.045).	Glycine	61-64	insulin	Homo sapiens	139-146
19815683-2	2010	The heavy and light chain variable region genes were amplified by the polymerase chain reaction (PCR) from hybridoma cell line FMC9 and assembled as an scFv fragment with a flexible linker (Gly(4)-Ser)(3).	Glycine	190-193	immunglobulin heavy chain variable region	Homo sapiens	152-156
20847447-4	2010	In this study, fifteen organic amino acid compounds (glycine, taurine, tramiprosate, and their derivatives) were employed to induce different fibrillogenic conditions for Abeta.	Glycine	53-60	amyloid beta precursor protein	Homo sapiens	171-176
19617589-8	2010	Mutant forms of Insig-1 and Insig-2 containing the Glu-to-Gly substitution fail to confer sterol regulation upon overexpressed Scap and reductase.	Glycine	58-61	insulin-induced gene 1 protein	Cricetulus griseus	16-23
19010062-6	2010	Insulin sensitivity was assessed by homeostasis model assessment (HOMA-S%) and insulin sensitivity index for glycemia (ISI(gly)) and insulin secretion by HOMA-B%.	Glycine	109-112	insulin	Homo sapiens	0-7
19617589-7	2010	This glycine residue localizes to the first membrane-spanning segment of Insig-2 and is also present in the corresponding region of Insig-1.	Glycine	5-12	insulin-induced gene 1 protein	Cricetulus griseus	132-139
19846563-6	2009	We conclude that Na(+) activates thrombin by securing the correct orientation of the Glu(192)-Gly(193) peptide bond, which is likely flipped in the absence of cation.	Glycine	94-97	coagulation factor II, thrombin	Homo sapiens	33-41
20635792-4	2010	Exon-specific amplification of genomic DNA by polymerase chain reaction followed by direct sequence analysis revealed a novel homozygous missense mutation at codon 48 in the C1q C gene causing a glycine-to-arginine substitution affecting the collagen-like region of C1q.	Glycine	195-202	complement C1q C chain	Homo sapiens	174-179
19506924-5	2010	In particular the replacement of serine 256 and isoleucine 359 in LeuT(Aa) with glycine and threonine in hGAT-1 seems to facilitate the selection of GABA as the main substrate by changing the hydrogen bonding pattern in the active site to the amino group of the substrate.	Glycine	80-87	solute carrier family 6 member 1	Homo sapiens	105-111
19944969-4	2010	EGFRvIII results from an in-frame deletion of exons 2 to 7 resulting in the fusion of exon 1 to exon 8 of the EGF receptor gene creating a novel glycine at the junction in the extracellular amino terminal domain.	Glycine	145-152	epidermal growth factor receptor	Homo sapiens	110-122
19508206-4	2010	Herein, we report the further design of the lead peptide 1 by addition of an Arg-Gly-Asp sequence to 1 to enhance binding to Grb2-SH2 and inducing apoptosis in cancer cells.	Glycine	81-84	growth factor receptor bound protein 2	Homo sapiens	125-129
20641584-4	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3 and alphavbeta5.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
20126315-2	2009	GlyT1 mutants, initially paralyzed by the build-up of the inhibitory neurotransmitter glycine, stage a gradual recovery that is associated with reductions in the strength of evoked glycinergic responses.	Glycine	86-93	solute carrier family 6 member 9	Danio rerio	0-5
19929018-10	2009	For normal incidence, we find an average percentage energy transfer to gly(8)-H(+) which is in excellent agreement with the experimentally measured value 10.1 +/- 0.8% for the octapeptide des-Arg(1)-bradykinin [J. Chem.	Glycine	71-74	kininogen 1	Homo sapiens	199-209
27713232-2	2009	The [14C]Gly-Sar uptake via PEPT1 was inhibited by Zn2+ and Cu2+ treatment in a concentration-dependent manner (Ki values 107 +- 23 and 19 +- 5 muM, respectively).	Glycine	9-12	solute carrier family 15 member 1	Homo sapiens	28-33
27713232-2	2009	The [14C]Gly-Sar uptake via PEPT1 was inhibited by Zn2+ and Cu2+ treatment in a concentration-dependent manner (Ki values 107 +- 23 and 19 +- 5 muM, respectively).	Glycine	9-12	latexin	Homo sapiens	144-147
27713232-3	2009	Kinetic analysis showed that the Kt of Gly-Sar uptake was increased 2-fold in the presence of zinc sulphate (150 muM) whereas the Vmax value were not affected suggesting that zinc ions inhibited Gly-Sar uptake by PEPT1 in a competitively manner.	Glycine	39-42	latexin	Homo sapiens	113-116
27713232-3	2009	Kinetic analysis showed that the Kt of Gly-Sar uptake was increased 2-fold in the presence of zinc sulphate (150 muM) whereas the Vmax value were not affected suggesting that zinc ions inhibited Gly-Sar uptake by PEPT1 in a competitively manner.	Glycine	39-42	solute carrier family 15 member 1	Homo sapiens	213-218
19948960-3	2009	Get3 consists of an ATPase and alpha-helical subdomain enriched in methionine and glycine residues.	Glycine	82-89	guided entry of tail-anchored proteins factor 3, ATPase	Homo sapiens	0-4
20641262-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
20641458-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
20641917-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	fibrinogen beta chain	Homo sapiens	134-144
19726695-0	2009	Expression of glycine-activated diheteromeric NR1/NR3 receptors in human embryonic kidney 293 cells Is NR1 splice variant-dependent.	Glycine	14-21	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	46-49
19909274-2	2009	The differences are, to a large extent, determined by the identities of the GluN2 (glutamate-binding) NMDAR subunits that are co-expressed with GluN1 (glycine-binding) subunits, which form the final tetrameric NMDAR assembly.	Glycine	151-158	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	144-149
19280639-6	2009	The comparison of these three structures with those previously reported for other ribonuclease swapped dimers strongly suggests that, in addition to Pro19 and Leu28, the presence of a glycine at the N-terminal end of the hinge peptide is also important to push the swapped form of RNase A dimer into the compact quaternary organization observed for NCD-BS.	Glycine	184-191	ribonuclease pancreatic	Bos taurus	281-288
19841468-1	2009	Glycine transporter (GlyT1) function is typically measured by radiolabeled glycine uptake using lysis methods or scintillation proximity assays (SPAs), which have limited throughput.	Glycine	75-82	solute carrier family 6 member 9	Homo sapiens	21-26
19726695-0	2009	Expression of glycine-activated diheteromeric NR1/NR3 receptors in human embryonic kidney 293 cells Is NR1 splice variant-dependent.	Glycine	14-21	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	103-106
19726695-6	2009	However, robust glycine-activated currents were generated in cells transfected with NR3(A or B) and either NR1-2a, NR1-3a, or NR1-4a, and current density was correlated with NR1 C-terminal length.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	107-110
19726695-6	2009	However, robust glycine-activated currents were generated in cells transfected with NR3(A or B) and either NR1-2a, NR1-3a, or NR1-4a, and current density was correlated with NR1 C-terminal length.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	115-118
19726695-1	2009	In oocytes, glycine activates receptors formed by diheteromeric combinations of N-methyl-d-aspartate (NMDA) NR1 and NR3 subunits.	Glycine	12-19	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	108-111
19726695-6	2009	However, robust glycine-activated currents were generated in cells transfected with NR3(A or B) and either NR1-2a, NR1-3a, or NR1-4a, and current density was correlated with NR1 C-terminal length.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	115-118
19726695-6	2009	However, robust glycine-activated currents were generated in cells transfected with NR3(A or B) and either NR1-2a, NR1-3a, or NR1-4a, and current density was correlated with NR1 C-terminal length.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	115-118
19745105-4	2009	An independent replication study in 1244 subjects from the San Diego Veterans Affairs Hypertension Cohort confirmed that Gly(49)/Gly(49) homozygotes displayed the least rapid decline of eGFR over approximately 3.6 years.	Glycine	121-124	epidermal growth factor receptor	Homo sapiens	186-190
19726695-8	2009	In contrast, large currents were observed when an extracellular phenylalanine in NR1-1a that influences glycine access was mutated to alanine.	Glycine	104-111	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	81-84
19726695-9	2009	A separate mutation in NR1-1a that disrupts glycine binding did not generate responses in NR1-1a/NR3A receptors alone, but it produced a greater than 30-fold potentiation of currents during coapplication of glycine and the glycine antagonist 7-chlorokynurenic acid.	Glycine	44-51	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	23-26
19726695-9	2009	A separate mutation in NR1-1a that disrupts glycine binding did not generate responses in NR1-1a/NR3A receptors alone, but it produced a greater than 30-fold potentiation of currents during coapplication of glycine and the glycine antagonist 7-chlorokynurenic acid.	Glycine	207-214	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	23-26
19726695-9	2009	A separate mutation in NR1-1a that disrupts glycine binding did not generate responses in NR1-1a/NR3A receptors alone, but it produced a greater than 30-fold potentiation of currents during coapplication of glycine and the glycine antagonist 7-chlorokynurenic acid.	Glycine	207-214	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	23-26
19660531-1	2009	Gephyrin is a tubulin-binding protein that acts as a scaffold for clustering glycine and GABA(A) receptors at postsynaptic sites.	Glycine	77-84	gephyrin	Rattus norvegicus	0-8
19745105-4	2009	An independent replication study in 1244 subjects from the San Diego Veterans Affairs Hypertension Cohort confirmed that Gly(49)/Gly(49) homozygotes displayed the least rapid decline of eGFR over approximately 3.6 years.	Glycine	129-132	epidermal growth factor receptor	Homo sapiens	186-190
19706311-6	2009	Moreover, the significant factors identified by multivariate analyses were BMI and serum triglyceride for AM-NH(2) and diastolic blood pressure, insulin, high-density lipoprotein-cholesterol, and plasma renin activity for AM-Gly.	Glycine	225-228	renin	Homo sapiens	203-208
20193176-4	2009	RESULTS: A novel missense mutation c.706T &gt; C was identified in exon 6 of MYBPC3 gene in three HCM patients, which resulted a Serine (S) to Glycine (G) exchange at amino acid residue 236 (S236G).	Glycine	143-150	myosin binding protein C3	Homo sapiens	77-83
19683594-3	2009	We have previously observed that the mitochondrial protein, cytochrome c, is capable of catalyzing the formation of the prototypic arachidonoyl amino acid, arachidonoyl glycine, utilizing arachidonoyl CoA and glycine as substrates, in the presence of hydrogen peroxide.	Glycine	169-176	cytochrome c, somatic	Homo sapiens	60-72
19715676-6	2009	AT with a P2-Phe inhibited thrombin with &gt;150-fold impaired reactivity, however, the defect was restored by either pentasaccharide or by replacing Leu-99 of thrombin with a Gly.	Glycine	176-179	coagulation factor II, thrombin	Homo sapiens	27-35
19905915-8	2009	We found a significant association between favorable therapeutic response to inhaled beta(2)-adrenergic agonists in asthmatic children and the Arg/Arg phenotype at position 16 of the beta(2)AR [OR = 1.77; 95% CI (1.01; 3.1); p = 0.029], compared with the Arg/Gly or Gly/Gly phenotypes.	Glycine	259-262	G protein-coupled receptor 162	Homo sapiens	85-91
19905915-8	2009	We found a significant association between favorable therapeutic response to inhaled beta(2)-adrenergic agonists in asthmatic children and the Arg/Arg phenotype at position 16 of the beta(2)AR [OR = 1.77; 95% CI (1.01; 3.1); p = 0.029], compared with the Arg/Gly or Gly/Gly phenotypes.	Glycine	266-269	G protein-coupled receptor 162	Homo sapiens	85-91
19905915-8	2009	We found a significant association between favorable therapeutic response to inhaled beta(2)-adrenergic agonists in asthmatic children and the Arg/Arg phenotype at position 16 of the beta(2)AR [OR = 1.77; 95% CI (1.01; 3.1); p = 0.029], compared with the Arg/Gly or Gly/Gly phenotypes.	Glycine	266-269	G protein-coupled receptor 162	Homo sapiens	85-91
19797941-2	2009	This pentapeptide is rapidly, and essentially completely, hydrolyzed at the tyrosine-glycine bond by bacitracin-sensitive aminopeptidase(s) (AP); neither dipeptidyl peptidase(s) (N-carboxyphenylmethyl leucine and captopril) nor peptidyl dipeptidase(s) (thiorphan) inhibitors altered the kinetics of MET degradation.	Glycine	85-92	carboxypeptidase Q	Homo sapiens	122-136
19666693-6	2009	The PPARD CC + PPARGC1A Gly/Gly genotypes were more frequently found in the elite endurance athletes than in national-level endurance athletes (P &lt; 0.000).	Glycine	24-27	PPARG coactivator 1 alpha	Homo sapiens	15-23
19666693-6	2009	The PPARD CC + PPARGC1A Gly/Gly genotypes were more frequently found in the elite endurance athletes than in national-level endurance athletes (P &lt; 0.000).	Glycine	28-31	PPARG coactivator 1 alpha	Homo sapiens	15-23
19666693-9	2009	However, a higher frequency of the PPARGC1A Gly/Gly + PPARD CC genotype is associated with elite-level endurance athletes.	Glycine	44-47	PPARG coactivator 1 alpha	Homo sapiens	35-43
19666693-9	2009	However, a higher frequency of the PPARGC1A Gly/Gly + PPARD CC genotype is associated with elite-level endurance athletes.	Glycine	48-51	PPARG coactivator 1 alpha	Homo sapiens	35-43
19427400-6	2009	A typical fibronectin type III (FNIII) domain was identified in p48.2 between Arg(176) and Pro(261) in which a palindromic Arg-Gly-Asp (RGD) repeat plus a putative Trp-Ser-X-Trp-Ser (WSXWS) motif were found at the domain"s C-terminus.	Glycine	127-130	interferon regulatory factor 9	Homo sapiens	64-67
19864664-5	2009	A novel familial ALS mutation in TDP-43 was identified that substitutes a highly conserved residue (G294V) and is predicted to disrupt the glycine rich domain in the C terminus, a region that plays a role in RNA binding and is required for the exon skipping activity of TDP-43.	Glycine	139-146	TAR DNA binding protein	Homo sapiens	33-39
19864664-5	2009	A novel familial ALS mutation in TDP-43 was identified that substitutes a highly conserved residue (G294V) and is predicted to disrupt the glycine rich domain in the C terminus, a region that plays a role in RNA binding and is required for the exon skipping activity of TDP-43.	Glycine	139-146	TAR DNA binding protein	Homo sapiens	270-276
19247805-4	2009	One single nucleotide polymorphism (SNP) was detected in each gene (g. 149G&gt;T polymorphism in the porcine ANG gene, which resulted in an amino acid change from glycine to valine, g. 296A&gt;G polymorphism in the porcine RNASE1 gene and g. 389C&gt;T polymorphism in the porcine RNASE6 gene).	Glycine	163-170	ribonuclease pancreatic	Sus scrofa	223-229
19602541-3	2009	This includes an F box characteristic of the substrate-binding subunit in Skp, Cullin, and F box (SCF)-type ubiquitin E3 ligase complexes and a variant ubiquitin E2 conjugase domain where the active site cysteine is replaced by a glycine.	Glycine	230-237	supercoiling factor	Drosophila melanogaster	98-101
20067119-7	2009	The apoB100 levels increased in the non-obese females with genotype Arg/Arg and decreased in the obese females with Arg/Gly (P &lt; 0.05 ).	Glycine	120-123	apolipoprotein B	Homo sapiens	4-11
19744924-11	2009	Further mutational analysis suggested that additional mechanisms associated with methylation of Mre11 at the C-terminal glycine-arginine-rich domain contributed to the promotion of D-NHEJ by Mre11.	Glycine	120-127	MRE11 homolog, double strand break repair nuclease	Homo sapiens	96-101
19808791-0	2009	Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis.	Glycine	25-32	TAR DNA binding protein	Homo sapiens	13-19
19808791-4	2009	TDP-43 possesses two RNA binding domains (RBD) and a glycine-rich C terminus classifying it with other heterogeneous nuclear ribonucleoproteins known as 2XRBD-Gly proteins.	Glycine	53-60	TAR DNA binding protein	Homo sapiens	0-6
19808791-7	2009	Currently, 29 different TARDBP missense mutations have been reported in 51 unrelated sporadic or familial ALS cases and two cases of ALS plus concomitant frontotemporal lobar degeneration with a remarkable concentration of mutations in the C-terminal glycine-rich domain of TDP-43.	Glycine	251-258	TAR DNA binding protein	Homo sapiens	24-30
19824767-1	2009	Local availability of glycine near N-methyl-D-aspartate receptors (NMDARs) is partly regulated by neuronal glycine transporter 1 (GlyT1), which can therefore modulate NMDAR function because binding to the glycine site of the NMDAR is necessary for channel activation.	Glycine	22-29	solute carrier family 6 member 9	Homo sapiens	107-128
19824767-1	2009	Local availability of glycine near N-methyl-D-aspartate receptors (NMDARs) is partly regulated by neuronal glycine transporter 1 (GlyT1), which can therefore modulate NMDAR function because binding to the glycine site of the NMDAR is necessary for channel activation.	Glycine	22-29	solute carrier family 6 member 9	Homo sapiens	130-135
19824767-1	2009	Local availability of glycine near N-methyl-D-aspartate receptors (NMDARs) is partly regulated by neuronal glycine transporter 1 (GlyT1), which can therefore modulate NMDAR function because binding to the glycine site of the NMDAR is necessary for channel activation.	Glycine	107-114	solute carrier family 6 member 9	Homo sapiens	130-135
19789338-4	2009	Comparative analysis of substituted melanoma-differentiation antigen gp100 in complex with H-2D(b) revealed that combined introduction of glycine and proline residues at the nonanchor positions 2 and 3, respectively, resulted in an agonistic altered peptide with dramatically enhanced binding affinity, stability, and immunogenicity of this TAA.	Glycine	138-145	premelanosome protein	Homo sapiens	69-74
19744924-11	2009	Further mutational analysis suggested that additional mechanisms associated with methylation of Mre11 at the C-terminal glycine-arginine-rich domain contributed to the promotion of D-NHEJ by Mre11.	Glycine	120-127	MRE11 homolog, double strand break repair nuclease	Homo sapiens	191-196
19347867-7	2009	Enzymatic assays using different recombinant COX-2 variants showed that COX-2-(587)Arg had significantly higher activity towards arachidonic acid than COX-2-(587)Gly (13.8 +/- 3.2 U/mg vs. 11.2 +/- 2.4 U/mg; P = 0.012).	Glycine	162-165	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	45-50
19347867-7	2009	Enzymatic assays using different recombinant COX-2 variants showed that COX-2-(587)Arg had significantly higher activity towards arachidonic acid than COX-2-(587)Gly (13.8 +/- 3.2 U/mg vs. 11.2 +/- 2.4 U/mg; P = 0.012).	Glycine	162-165	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	72-77
19347867-7	2009	Enzymatic assays using different recombinant COX-2 variants showed that COX-2-(587)Arg had significantly higher activity towards arachidonic acid than COX-2-(587)Gly (13.8 +/- 3.2 U/mg vs. 11.2 +/- 2.4 U/mg; P = 0.012).	Glycine	162-165	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	72-77
19685173-5	2009	RESULTS: E595C- and G594C-hPEPT1 showed negligible Gly-Sar uptake.	Glycine	51-54	solute carrier family 15 member 1	Homo sapiens	26-32
19664057-0	2009	Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro.	Glycine	64-71	transferrin	Homo sapiens	93-104
19705807-1	2009	The chief sources of cyanide (CN(-)) in humans are tobacco and occupationally derived smoke, inflammation [vis-a-vis myeloperoxidase (MPO)-induced chlorination of glycine], and microbial cyanogenesis (including Pseudomonas aeruginosa infection of the cystic fibrosis lung).	Glycine	163-170	myeloperoxidase	Homo sapiens	134-137
19639556-0	2009	Mass spectrometry study of PRL-3 phosphatase inactivation by disulfide bond formation and cysteine into glycine conversion.	Glycine	104-111	protein tyrosine phosphatase 4A3	Homo sapiens	27-32
19639556-3	2009	By liquid chromatography combined with selective alkylation and mass spectrometry, we found two main PRL-3 inactivation pathways: a disulfide bond formation between the catalytic C104 and C49, blocking the enzyme in an inactive oxidized form, or the conversion of the catalytic C104 into glycine.	Glycine	288-295	protein tyrosine phosphatase 4A3	Homo sapiens	101-106
19570983-4	2009	LIP2 and LIP5 are required for lipoylation of all three mitochondrial target proteins: Lat1 and Kgd2, the respective E2 subunits of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, and Gcv3, the H protein of the glycine cleavage enzyme.	Glycine	225-232	lipoyl(octanoyl) transferase LIP2	Saccharomyces cerevisiae S288C	0-4
19570983-4	2009	LIP2 and LIP5 are required for lipoylation of all three mitochondrial target proteins: Lat1 and Kgd2, the respective E2 subunits of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, and Gcv3, the H protein of the glycine cleavage enzyme.	Glycine	225-232	dihydrolipoyllysine-residue acetyltransferase	Saccharomyces cerevisiae S288C	87-91
19617896-0	2009	Glycine inhibits the LPS-induced increase in cytosolic Ca2+ concentration and TNFalpha production in cardiomyocytes by activating a glycine receptor.	Glycine	0-7	tumor necrosis factor	Rattus norvegicus	78-86
19617896-6	2009	GLY did not inhibit TNFalpha production induced by LPS at concentrations below 10 ng/mL but did significantly decrease TNFalpha release stimulated by 100 microg/mL LPS and prevented an LPS-induced increase in [Ca2+]c, which was reversed by strychnine, a glycine receptor antagonist.	Glycine	0-3	tumor necrosis factor	Rattus norvegicus	119-127
19617896-9	2009	CONCLUSION: Cardiomyocytes possess the glycine-gated chloride channel, through which GLY prevents the increase in [Ca2+]c and inhibits the TNFalpha production induced by LPS at high doses in neonatal rat cardiomyocytes.	Glycine	39-46	tumor necrosis factor	Rattus norvegicus	139-147
19617896-9	2009	CONCLUSION: Cardiomyocytes possess the glycine-gated chloride channel, through which GLY prevents the increase in [Ca2+]c and inhibits the TNFalpha production induced by LPS at high doses in neonatal rat cardiomyocytes.	Glycine	85-88	tumor necrosis factor	Rattus norvegicus	139-147
19416251-8	2009	Mutations in glycine 59 of Cx26 are associated with PPK-deafness syndrome, and the similar phenotype here supports the observed heteromeric channel formation; the dominant nature of the mutation suggests an effect on gap junctions similar to that of the comparable mutation in Cx26.	Glycine	13-20	gap junction protein beta 2	Homo sapiens	27-31
19416251-8	2009	Mutations in glycine 59 of Cx26 are associated with PPK-deafness syndrome, and the similar phenotype here supports the observed heteromeric channel formation; the dominant nature of the mutation suggests an effect on gap junctions similar to that of the comparable mutation in Cx26.	Glycine	13-20	gap junction protein beta 2	Homo sapiens	277-281
19496616-4	2009	The peptide flip occurs in p38alpha kinase due to the critical glycine residue marked by its conformational flexibility.	Glycine	63-70	mitogen-activated protein kinase 14	Homo sapiens	27-35
19487695-3	2009	Conventional NMDA receptors are obligatory heterotetramers composed of two glycine-binding NR1 subunits and two glutamate-binding NR2 subunits.	Glycine	75-82	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	91-94
19580321-3	2009	In this study, we present a combined magic angle spinning solid-state and solution NMR study of the MTBP CAP-Gly domain of mammalian dynactin and its interaction with paclitaxel-stabilized microtubules.	Glycine	109-112	MDM2 binding protein	Homo sapiens	100-104
19478091-2	2009	A synthetic peptide corresponding to the first 23 amino acids of human connexin37 was prepared, and circular dichroism and nuclear magnetic resonance studies showed that this N-terminal peptide was predominantly alpha-helical between glycine 5 and glutamate 16.	Glycine	234-241	gap junction protein alpha 4	Homo sapiens	71-81
19473961-1	2009	The glycine transporter GLYT1 regulates both glycinergic and glutamatergic neurotransmission by controlling the reuptake of glycine at synapses.	Glycine	4-11	solute carrier family 6 member 9	Homo sapiens	24-29
19341362-3	2009	Glutamine, a mixture of leucine, aspartic acid and glycine, and a mixture of leucine, glutamine and aspartic acid, were the most effective for the expression of IL-2.	Glycine	51-58	interleukin 2	Homo sapiens	161-165
19473027-2	2009	Previous studies demonstrated that the substitution of Gly(5) with d-amino acids generates NPSR antagonists.	Glycine	55-58	neuropeptide S receptor 1	Homo sapiens	91-95
19427831-4	2009	The glycine transport ability of GLYT1 is also highly dependent on the integrity of this area.	Glycine	4-11	solute carrier family 6 member 9	Homo sapiens	33-38
19427831-5	2009	Together, the results suggest that GLYT1 and membrane rafts are co-localized in the membrane, and that this influences the rate of glycine transport.	Glycine	131-138	solute carrier family 6 member 9	Homo sapiens	35-40
19562643-4	2009	Glycine levels, in turn, are regulated by glycine transporter type 1 (GlyT1), which serves to maintain low subsaturating glycine levels in the vicinity of the NMDAR.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	42-68
19679043-4	2009	In addition, African American-predominant CYP1B1 432 Val allele was significantly more often found in the cases than in the controls overall and the HSD17B1 312 Gly allele was specifically associated with premenopausal breast cancer risk (OR=3.00, 95%CI 1.29-6.99).	Glycine	161-164	hydroxysteroid 17-beta dehydrogenase 1	Homo sapiens	149-156
19562643-4	2009	Glycine levels, in turn, are regulated by glycine transporter type 1 (GlyT1), which serves to maintain low subsaturating glycine levels in the vicinity of the NMDAR.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	70-75
19562643-4	2009	Glycine levels, in turn, are regulated by glycine transporter type 1 (GlyT1), which serves to maintain low subsaturating glycine levels in the vicinity of the NMDAR.	Glycine	42-49	solute carrier family 6 member 9	Homo sapiens	70-75
19243863-2	2009	We use as reference the glycine site in the NR1 subunit of the NMDA receptor (Glycine(B)-iGluR-NMDA).	Glycine	24-31	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	44-47
19705749-12	2009	It was demonstrated that Gly allele of the Arg213Gly polymorphic locus of the SOD3 gene marked the risk for COPD in the ethnic group of Tatars (OR = 2.23; 95% CI, 1.22 to 4.1).	Glycine	25-28	superoxide dismutase 3	Homo sapiens	78-82
19394328-7	2009	We did however observe a small increase in glycine potency, in the presence of ethanol, at GluN1/GluN2A NMDA receptors.	Glycine	43-50	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	97-103
19373110-10	2009	Interestingly, the odds ratio was 7.64 for individuals having a combination of the Gly/Gly genotype of ADRB2 and Glu/Glu genotype of NOS3 when compared with those having a combination of Arg/Arg and Arg/Gly genotypes of ADRB2 and Asp/Asp and Asp/Glu genotypes of NOS3.	Glycine	83-86	nitric oxide synthase 3	Homo sapiens	263-267
19342448-6	2009	Function-blocking antibodies directed against integrin alpha5beta1 or soluble Arg-Gly-Asp peptide fragments derived from FN specifically inhibited GPR30-mediated epidermal growth factor receptor transactivation.	Glycine	82-85	fibronectin 1	Homo sapiens	121-123
19398000-2	2009	In fibrillar collagens, MMP-1, MMP-8, and MMP-13 cleave a specific glycine-isoleucine or glycine-leucine bond, despite the presence of this sequence in other parts of the protein.	Glycine	67-74	matrix metallopeptidase 13	Homo sapiens	42-48
19398000-2	2009	In fibrillar collagens, MMP-1, MMP-8, and MMP-13 cleave a specific glycine-isoleucine or glycine-leucine bond, despite the presence of this sequence in other parts of the protein.	Glycine	89-96	matrix metallopeptidase 13	Homo sapiens	42-48
19342448-6	2009	Function-blocking antibodies directed against integrin alpha5beta1 or soluble Arg-Gly-Asp peptide fragments derived from FN specifically inhibited GPR30-mediated epidermal growth factor receptor transactivation.	Glycine	82-85	epidermal growth factor receptor	Homo sapiens	162-194
19515926-3	2009	Here, we show that glycine 33 (G33) of the central GxxxG interaction motif within the hydrophobic Abeta sequence is important for the aggregation dynamics of the peptide.	Glycine	19-26	amyloid beta precursor protein	Homo sapiens	98-103
20641908-1	2004	The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits with multiple regulatory binding sites for glutamate, glycine, Mg(2+), polyamine, and drugs such as phencyclidine (PCP) (2).	Glycine	132-139	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	53-56
19393690-6	2009	Glycine transporter (GlyT) 1 and GlyT2, which are located in glial cells and neurons, respectively play important roles by clearing synaptically released glycine or supplying glycine to glycinergic neurons to regulate glycinergic neurotransmission.	Glycine	154-161	solute carrier family 6 member 9	Homo sapiens	0-28
19393690-6	2009	Glycine transporter (GlyT) 1 and GlyT2, which are located in glial cells and neurons, respectively play important roles by clearing synaptically released glycine or supplying glycine to glycinergic neurons to regulate glycinergic neurotransmission.	Glycine	175-182	solute carrier family 6 member 9	Homo sapiens	0-28
19374720-7	2009	Coexpression of a Rab11 dominant negative mutant with recombinant GLYT2 impaired transporter trafficking and glycine transport.	Glycine	109-116	RAB11a, member RAS oncogene family	Rattus norvegicus	18-23
19020553-1	2009	Human hornerin (HRNR) is a 245 kDa S100 fused-type protein which contains 95% tandem quasi-repeating glycine- and serine-rich domains.	Glycine	101-108	hornerin	Homo sapiens	6-14
19129013-5	2009	In this study, we hypothesized that PES surfaces modified with a peptide sequence based from fibronectin, such as Arg-Gly-Asp (RGD), Arg-Gly-Asp-Ser and Gly-Arg-Gly-Asp-Ser, would increase ASC adhesion compared to unmodified PES surfaces.	Glycine	118-121	fibronectin 1	Homo sapiens	93-104
19410451-2	2009	We describe herein the structure-activity relationships (SAR) of a structurally novel class of GlyT1 inhibitors following on a lead derived from high throughput screening, which shows good selectivity for GlyT1 and potent activity in elevating CSF levels of glycine.	Glycine	258-265	solute carrier family 6 member 9	Homo sapiens	95-100
19441084-4	2009	Because it is known that matrix metalloproteinases (MMPs) cleave COL2 in vitro at the Gly(775)-Leu(776) bond, it has been reasoned that, if such cleavage is detected in relation to the canals, it can be concluded that a collagenase is involved.	Glycine	86-89	matrix metallopeptidase 13	Homo sapiens	52-56
19020553-1	2009	Human hornerin (HRNR) is a 245 kDa S100 fused-type protein which contains 95% tandem quasi-repeating glycine- and serine-rich domains.	Glycine	101-108	hornerin	Homo sapiens	16-20
19120338-9	2009	RESULTS: Direct sequencing revealed a heterozygous glycine substitution mutation, p.G627V, in COL17A1.	Glycine	51-58	collagen type XVII alpha 1 chain	Homo sapiens	94-101
19504859-1	2009	The adsorption mechanism of dipeptides namely Gly-Glu, Asp-Glu with protein layer was successfully examined on cytochrome c (Cyt.c) surface probing by fluorescent dye molecule.	Glycine	46-49	cytochrome c, somatic	Homo sapiens	111-123
19504859-1	2009	The adsorption mechanism of dipeptides namely Gly-Glu, Asp-Glu with protein layer was successfully examined on cytochrome c (Cyt.c) surface probing by fluorescent dye molecule.	Glycine	46-49	cytochrome c, somatic	Homo sapiens	125-130
19309309-6	2009	A GST (glutathione transferase) pulldown assay using different deletion mutants revealed that the RGG (Arg-Gly-Gly) region of RHA was responsible for the interaction with beta-actin, and this dominant-negative mutant reduced the recruitment of Pol II (RNA polymerase II) into PICs.	Glycine	107-110	DExH-box helicase 9	Homo sapiens	126-129
19309309-6	2009	A GST (glutathione transferase) pulldown assay using different deletion mutants revealed that the RGG (Arg-Gly-Gly) region of RHA was responsible for the interaction with beta-actin, and this dominant-negative mutant reduced the recruitment of Pol II (RNA polymerase II) into PICs.	Glycine	111-114	DExH-box helicase 9	Homo sapiens	126-129
19285963-3	2009	Interestingly, 18 of them were located in the C-terminal glycine-rich region of TDP-43.	Glycine	57-64	TAR DNA binding protein	Homo sapiens	80-86
18781650-6	2009	Ser(Reb)-Gly exhibited significantly increased uptake by PEPT1-expressing cells in comparison with that by mock cells.	Glycine	9-12	solute carrier family 15 member 1	Homo sapiens	57-62
19113917-2	2009	The Brtl mouse has a glycine substitution in col1a1 and is ideal for modeling the effects of bisphosphonate in classical OI.	Glycine	21-28	collagen, type I, alpha 1	Mus musculus	45-51
19369898-5	2009	RESULTS: There was a 1.198-fold increased micronucleus frequency for individuals carrying TDG 199Gly/Ser + Ser/Ser genotypes compared with those carrying Gly/Gly genotype (P &lt; 0.05).	Glycine	97-100	thymine DNA glycosylase	Homo sapiens	90-93
18781650-7	2009	The permeability of Ser(Reb)-Gly across a Caco-2 cell monolayer was significantly higher than that of rebamipide itself, and the transport was decreased in the presence of PEPT1 substrates.	Glycine	29-32	solute carrier family 15 member 1	Homo sapiens	172-177
19386107-2	2009	This model is particularly relevant to cancer cell metastasis to bone since BSP, bound to the alphavbeta3 integrin through its arginine-glycine-aspartic acid motif, could recruit MMP-2 to the cell surface.	Glycine	136-143	integrin binding sialoprotein	Homo sapiens	76-79
19412343-4	2009	Substitution of Ser-168 with Ala (or Gly) ablated production of infectious virus by cells transfected with a chimeric viral RNA (HJ3-5) containing core-NS2 sequences from the genotype 1a H77 virus within the background of genotype 2a JFH1 virus.	Glycine	37-40	NS2	Homo sapiens	152-155
19211556-9	2009	The crystal structure at 1.7-A resolution revealed that the dual mutation causes a shift of residue Gly(96) toward the glyphosate binding site, impairing efficient binding of glyphosate, while the side chain of Ile(97) points away from the substrate binding site, facilitating PEP utilization.	Glycine	100-103	phosphoenolpyruvate carboxylase 2	Zea mays	277-280
20560636-1	2009	Described herein is the chemical synthesis of the Cys(29)-Gly(77) glycopeptide domain (22) of erythropoietin.	Glycine	58-61	erythropoietin	Homo sapiens	94-108
20560636-4	2009	In contrast, by tuning the C-terminal acyl donor and using smaller peptide fragments, the Cys(29)-Gly(77) glycopeptide domain of erythropoietin was prepared through unconventional N --&gt; C termini condensation reactions.	Glycine	98-101	erythropoietin	Homo sapiens	129-143
19389353-5	2009	We identified a basepair substitution in exon 1 of the Six1 gene that changes a conserved glutamic acid (E) at position 121 to a glycine (G) in the Six1 homeodomain.	Glycine	129-136	sine oculis-related homeobox 1	Mus musculus	55-59
19389353-5	2009	We identified a basepair substitution in exon 1 of the Six1 gene that changes a conserved glutamic acid (E) at position 121 to a glycine (G) in the Six1 homeodomain.	Glycine	129-136	sine oculis-related homeobox 1	Mus musculus	148-152
19176531-7	2009	Movement of the ring toward H5 was also reflected in increased separation between the Cepsilon carbons of Lys(296) (H7) and Met(44) (H1) and between Gly(121) (H3) and the retinal C18 methyl group.	Glycine	149-152	Bardet-Biedl syndrome 9	Homo sapiens	179-182
19348678-6	2009	We provide evidence that functional excitatory glycine receptors formed regardless of the NR1 isoform, and their pharmacological profile matched the one reported for NR1-1a/NR3: glycine alone fully activated the receptors, which were insensitive to glutamate and block by Mg2+.	Glycine	47-54	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	166-169
19317748-7	2009	Interestingly, one of the novel HLA-DRB1 alleles (*1471) has a change that is not the typical glycine/valine dimorphism at codon 86, which plays a key role in peptide binding to DR molecules.	Glycine	94-101	major histocompatibility complex, class II, DR beta 1	Homo sapiens	32-40
19287951-6	2009	Similarly, BRCA1 cancer-predisposing mutation (61Cys-Gly) abrogated the ability to both bind Ubc9 as well as inhibit ERalpha activity suggesting physiological significance.	Glycine	53-56	estrogen receptor 1	Homo sapiens	117-124
19153190-0	2009	Glycine-extended gastrin inhibits apoptosis in Barrett"s oesophageal and oesophageal adenocarcinoma cells through JAK2/STAT3 activation.	Glycine	0-7	signal transducer and activator of transcription 3	Homo sapiens	119-124
19244382-2	2009	CO(2) also can be generated from the 2-carbon of glycine by 10-formyltetrahydrofolate-dehydrogenase and, after glycine-to-serine conversion by serine hydroxymethyltransferase, from the tricarboxylic acid cycle.	Glycine	49-56	aldehyde dehydrogenase 1 family member L1	Homo sapiens	60-99
19317748-8	2009	This is only the second DRB1 allele described that encodes an amino acid other than glycine or valine at this position.	Glycine	84-91	major histocompatibility complex, class II, DR beta 1	Homo sapiens	24-28
19237746-6	2009	The comparison shows that nucleotide-induced changes are localized to the glycine-rich loop region of DAPK.	Glycine	74-81	death associated protein kinase 1	Homo sapiens	102-106
19270403-0	2009	SK66-his, a novel glycine-rich peptide derived from Drosophila with antibacterial activity.	Glycine	18-25	uncharacterized protein	Drosophila melanogaster	0-4
19284992-0	2009	Glycine-rich region regulates cysteine-rich protein 1 binding to actin cytoskeleton.	Glycine	0-7	cysteine rich protein 1	Homo sapiens	30-53
19284992-1	2009	Cysteine-rich protein 1 (CRP1) has a unique structure with two well separated LIM domains, each followed by a glycine-rich region.	Glycine	110-117	cysteine rich protein 1	Homo sapiens	0-23
19284992-1	2009	Cysteine-rich protein 1 (CRP1) has a unique structure with two well separated LIM domains, each followed by a glycine-rich region.	Glycine	110-117	cysteine rich protein 1	Homo sapiens	25-29
19284992-3	2009	Experiments using truncated forms showed that the first LIM domain and glycine-rich region are necessary for CRP1 bundling of actin filaments and localization to the actin cytoskeleton.	Glycine	71-78	cysteine rich protein 1	Homo sapiens	109-113
19284992-4	2009	Furthermore, domain swapping experiments replacing the first glycine-rich region with the second resulted in the loss of CRP1 bundling activity and localization to the actin cytoskeleton, identifying seven critical amino acid residues.	Glycine	61-68	cysteine rich protein 1	Homo sapiens	121-125
19284992-5	2009	These results highlight the importance of the first glycine-rich region for CRP1 bundling activity and localization to the actin cytoskeleton.	Glycine	52-59	cysteine rich protein 1	Homo sapiens	76-80
19257898-9	2009	The most prevalent haplotype was dhfr Arg-59 with the dhps Gly-437 mutant and the dhps 540 wild type (85.5%).	Glycine	59-62	deoxyhypusine synthase	Homo sapiens	54-58
19317896-8	2009	Furthermore, they included a recurrent "public" amino acid motif (Glycine-Leucine-Glycine at positions 110-112-113 of the CDR3) rearranged with dominant TRBV and TRBJ segments and, in one case, associated with a full conservation of the entire TRB sequence.	Glycine	66-73	T cell receptor beta locus	Homo sapiens	153-156
19317896-8	2009	Furthermore, they included a recurrent "public" amino acid motif (Glycine-Leucine-Glycine at positions 110-112-113 of the CDR3) rearranged with dominant TRBV and TRBJ segments and, in one case, associated with a full conservation of the entire TRB sequence.	Glycine	82-89	T cell receptor beta locus	Homo sapiens	153-156
19265520-0	2009	The glycine brace: a component of Rab, Rho, and Ran GTPases associated with hinge regions of guanine- and phosphate-binding loops.	Glycine	4-11	RAB40A like	Homo sapiens	34-37
19265520-3	2009	RESULTS: Bayesian analysis of divergent patterns within a multiple alignment of Ras-like GTPase sequences identifies a structural component, termed here the glycine brace, as the feature that most distinguishes Rab, Rho/Rac, Ran and (to some degree) Ras family GTPases from other Ras-like GTPases.	Glycine	157-164	RAB40A like	Homo sapiens	80-95
19265520-3	2009	RESULTS: Bayesian analysis of divergent patterns within a multiple alignment of Ras-like GTPase sequences identifies a structural component, termed here the glycine brace, as the feature that most distinguishes Rab, Rho/Rac, Ran and (to some degree) Ras family GTPases from other Ras-like GTPases.	Glycine	157-164	RAB40A like	Homo sapiens	211-214
19265520-3	2009	RESULTS: Bayesian analysis of divergent patterns within a multiple alignment of Ras-like GTPase sequences identifies a structural component, termed here the glycine brace, as the feature that most distinguishes Rab, Rho/Rac, Ran and (to some degree) Ras family GTPases from other Ras-like GTPases.	Glycine	157-164	AKT serine/threonine kinase 1	Homo sapiens	220-223
19201665-5	2009	The validated method was successfully employed in the study of Gly-Sar uptake inhibition in Caco-2 cells by valcytarabine, a potential substrate of the peptide transporter 1 (PEPT1).	Glycine	63-66	solute carrier family 15 member 1	Homo sapiens	152-173
19208385-4	2009	In all of these patients, OI was caused by glycine mutations affecting exon 49 of the COL1A2 gene, which codes for the most carboxy-terminal part of the triple-helical domain of the collagen type I alpha 2 chain.	Glycine	43-50	collagen type I alpha 2 chain	Homo sapiens	86-92
19208385-4	2009	In all of these patients, OI was caused by glycine mutations affecting exon 49 of the COL1A2 gene, which codes for the most carboxy-terminal part of the triple-helical domain of the collagen type I alpha 2 chain.	Glycine	43-50	collagen type I alpha 2 chain	Homo sapiens	182-205
19061912-6	2009	A computational docking simulation supported that acrylamide directly bound to the active site of CK-BB where cysteine and glycine residues interacted mainly.	Glycine	123-130	creatine kinase B	Homo sapiens	98-103
19621799-4	2009	Also, enkephalins, VIP and SS are able to stimulate or suppress the inhibitory effect of GABA and glycine.	Glycine	98-105	vasoactive intestinal peptide	Felis catus	19-22
19201665-5	2009	The validated method was successfully employed in the study of Gly-Sar uptake inhibition in Caco-2 cells by valcytarabine, a potential substrate of the peptide transporter 1 (PEPT1).	Glycine	63-66	solute carrier family 15 member 1	Homo sapiens	175-180
19084598-8	2009	IFN-gamma 50 ng/ml increased Gly-Sar P(eff) 28.6% compared to controls (p=0.03).	Glycine	29-32	interferon gamma	Homo sapiens	0-9
19084598-10	2009	In controls and IFN-gamma treated cells, concentration dependent transport was seen with escalating concentrations of Gly-Sar.	Glycine	118-121	interferon gamma	Homo sapiens	16-25
19084598-12	2009	In summary, IFN-gamma increases h-PEPT1 expression and permeation of the dipeptide Gly-Sar in Caco-2 monolayers.	Glycine	83-86	interferon gamma	Homo sapiens	12-21
19244526-0	2009	Glycine inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia.	Glycine	0-7	tachykinin precursor 1	Homo sapiens	86-98
19074430-8	2009	EAAT2 has a Ser residue at position 441 with hairpin loop 2, whereas the corresponding residue in EAAT1 is a Gly residue.	Glycine	109-112	solute carrier family 1 member 2	Homo sapiens	0-5
18996969-1	2009	AIMS: A domain peptide (DP) matching the Gly(2460)-Pro(2495) region of the cardiac type-2 ryanodine receptor (RyR2), DPc10, is known to mimic channel dysfunction associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), owing to its interference in a normal interaction of the N-terminal (1-600) and central (2000-2500) domains (viz.	Glycine	41-44	ryanodine receptor 2	Canis lupus familiaris	110-114
19074430-8	2009	EAAT2 has a Ser residue at position 441 with hairpin loop 2, whereas the corresponding residue in EAAT1 is a Gly residue.	Glycine	109-112	solute carrier family 1 member 3	Homo sapiens	98-103
19254477-4	2009	However, DULP does not possess the highly conserved C-terminus Gly-Gly required for ubiquitin conjugation or the Lys-48 required for the formation of polyubiquitin chain to target substrates for degradation, suggesting it might be a novel ubiquitin-domain protein (UDP).	Glycine	63-66	transmembrane and ubiquitin like domain containing 1	Homo sapiens	9-13
19179283-3	2009	The widely used mouse strain C57BL/6J, harbors a SERT haplotype defined by 2 nonsynonymous coding variants [Gly-39 and Lys-152 (GK)].	Glycine	108-111	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	Mus musculus	49-53
19236233-6	2009	K57 substitution with a glycine in sCD38p impaired its ability to inhibit syncytia formation in MT-2/H9(IIIB) cell cocultures and gp120 binding to CD4 in a mouse T cell line expressing human but not mouse CD4.	Glycine	24-31	metallothionein 2	Mus musculus	96-100
19115956-5	2009	Glycylsarcosine (gly-sar, a typical substrate of PepT1) uptake by Caco-2 cells can be inhibited by 2 in a concentration-dependent manner, and IC(50) for 2 was 2.18 +/- 0.12 mM.	Glycine	17-20	solute carrier family 15 member 1	Homo sapiens	49-54
18996574-5	2009	RESULTS: All subunits of Gly m 5 (beta-conglycinin) and Gly m 6 (glycinin) were IgE-reactive: 53% (16/30) of the study subjects had specific IgE to at least 1 major storage protein, 43% (13/30) to Gly m 5 , and 36% (11/30) to Gly m 6.	Glycine	25-28	immunoglobulin heavy constant epsilon	Homo sapiens	80-83
18996574-5	2009	RESULTS: All subunits of Gly m 5 (beta-conglycinin) and Gly m 6 (glycinin) were IgE-reactive: 53% (16/30) of the study subjects had specific IgE to at least 1 major storage protein, 43% (13/30) to Gly m 5 , and 36% (11/30) to Gly m 6.	Glycine	25-28	immunoglobulin heavy constant epsilon	Homo sapiens	141-144
18996574-5	2009	RESULTS: All subunits of Gly m 5 (beta-conglycinin) and Gly m 6 (glycinin) were IgE-reactive: 53% (16/30) of the study subjects had specific IgE to at least 1 major storage protein, 43% (13/30) to Gly m 5 , and 36% (11/30) to Gly m 6.	Glycine	56-59	immunoglobulin heavy constant epsilon	Homo sapiens	80-83
18996574-5	2009	RESULTS: All subunits of Gly m 5 (beta-conglycinin) and Gly m 6 (glycinin) were IgE-reactive: 53% (16/30) of the study subjects had specific IgE to at least 1 major storage protein, 43% (13/30) to Gly m 5 , and 36% (11/30) to Gly m 6.	Glycine	56-59	immunoglobulin heavy constant epsilon	Homo sapiens	80-83
18996574-5	2009	RESULTS: All subunits of Gly m 5 (beta-conglycinin) and Gly m 6 (glycinin) were IgE-reactive: 53% (16/30) of the study subjects had specific IgE to at least 1 major storage protein, 43% (13/30) to Gly m 5 , and 36% (11/30) to Gly m 6.	Glycine	56-59	immunoglobulin heavy constant epsilon	Homo sapiens	80-83
18996574-6	2009	Gly m 5 was IgE-reactive in 5 of 5 and Gly m 6 in 3 of 5 children.	Glycine	0-3	immunoglobulin heavy constant epsilon	Homo sapiens	12-15
18996574-7	2009	IgE-binding to Gly m 5 or Gly m 6 was found in 86% (6/7) subjects with anaphylaxis to soy and in 55% (6/11) of subjects with moderate but only 33% (4/12) of subjects with mild soy-related symptoms.	Glycine	15-18	immunoglobulin heavy constant epsilon	Homo sapiens	0-3
18996574-7	2009	IgE-binding to Gly m 5 or Gly m 6 was found in 86% (6/7) subjects with anaphylaxis to soy and in 55% (6/11) of subjects with moderate but only 33% (4/12) of subjects with mild soy-related symptoms.	Glycine	26-29	immunoglobulin heavy constant epsilon	Homo sapiens	0-3
18996574-8	2009	The odds ratio (P &lt; .05) for severe versus mild allergic reactions in subjects with specific IgE to Gly m 5 or Gly m6 was 12/1.	Glycine	103-106	immunoglobulin heavy constant epsilon	Homo sapiens	96-99
19033885-8	2009	Molecular modeling suggested that the glutamic acid-233 forms a salt bridge with lysine-23 in the N-terminal domain of RAD51D, and the glycine substitution may disrupt an interdomain interaction.	Glycine	135-142	RAD51 paralog D	Homo sapiens	119-125
20641947-0	2004	(99m)Tc Nitrido(diphosphine)-Cys-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2).	Glycine	58-61	gastrin releasing peptide receptor	Homo sapiens	239-252
20641947-0	2004	(99m)Tc Nitrido(diphosphine)-Cys-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2).	Glycine	58-61	gastrin releasing peptide receptor	Homo sapiens	254-258
18845625-5	2009	Treatment of NOD mice with a glucagon-like peptide 2 (GLP-2) analog, synthetic human [Gly(2)] glucagon-like peptide-2 (h[Gly(2)]GLP-2, increased the length and weight of the small bowel and significantly improved jejunal transepithelial resistance.	Glycine	86-89	glucagon	Homo sapiens	94-117
18845625-5	2009	Treatment of NOD mice with a glucagon-like peptide 2 (GLP-2) analog, synthetic human [Gly(2)] glucagon-like peptide-2 (h[Gly(2)]GLP-2, increased the length and weight of the small bowel and significantly improved jejunal transepithelial resistance.	Glycine	121-124	glucagon	Homo sapiens	94-117
18824844-8	2009	The analysis of mRNA expressions of Th1 (t-bet, TNF-alpha, IL-1beta) and Th2 (gata-3, IL-4, IL-10) cytokines showed a Th1-polarized response in Gly-AKI rats that was aggravated with the anti-HGF treatment.	Glycine	144-147	tumor necrosis factor	Rattus norvegicus	48-57
18824844-8	2009	The analysis of mRNA expressions of Th1 (t-bet, TNF-alpha, IL-1beta) and Th2 (gata-3, IL-4, IL-10) cytokines showed a Th1-polarized response in Gly-AKI rats that was aggravated with the anti-HGF treatment.	Glycine	144-147	interleukin 1 beta	Rattus norvegicus	59-67
18824844-8	2009	The analysis of mRNA expressions of Th1 (t-bet, TNF-alpha, IL-1beta) and Th2 (gata-3, IL-4, IL-10) cytokines showed a Th1-polarized response in Gly-AKI rats that was aggravated with the anti-HGF treatment.	Glycine	144-147	GATA binding protein 3	Rattus norvegicus	78-84
18835373-3	2009	The increase of the intracellular calcium concentration ([Ca2+](i)) and reactive oxygen species (ROS) release in cells incubated with glycine (0.1 to 10 mM) and stimulated with fMLP or PMA were compared with glycine-free controls.	Glycine	134-141	formyl peptide receptor 1	Homo sapiens	177-181
18835373-3	2009	The increase of the intracellular calcium concentration ([Ca2+](i)) and reactive oxygen species (ROS) release in cells incubated with glycine (0.1 to 10 mM) and stimulated with fMLP or PMA were compared with glycine-free controls.	Glycine	208-215	formyl peptide receptor 1	Homo sapiens	177-181
18835373-4	2009	Glycine inhibited ROS production but increased [Ca2+](i) signal produced by fMLP.	Glycine	0-7	formyl peptide receptor 1	Homo sapiens	76-80
18657556-6	2009	DHP inhibition was use-dependent and independent of glycine concentration, consistent with a pore-blocking mode of action.	Glycine	52-59	dihydropyrimidinase	Homo sapiens	0-3
19114635-3	2009	The importance of the signature sequence is attested by the fact that a glycine to aspartate mutation (i.e., G551D) in cystic fibrosis transmembrane conductance regulator (CFTR) results in a severe phenotype of cystic fibrosis.	Glycine	72-79	CF transmembrane conductance regulator	Homo sapiens	119-170
19114635-3	2009	The importance of the signature sequence is attested by the fact that a glycine to aspartate mutation (i.e., G551D) in cystic fibrosis transmembrane conductance regulator (CFTR) results in a severe phenotype of cystic fibrosis.	Glycine	72-79	CF transmembrane conductance regulator	Homo sapiens	172-176
19365107-10	2009	Upon tumor necrosis factor-alpha stimulation, IL-6 and IL-8 mRNA and protein levels in A549-PLA2G2D-Ser cells were elevated compared with those of A549-PLA2G2D-Gly cells.	Glycine	160-163	tumor necrosis factor	Homo sapiens	5-32
18771702-0	2008	Glycine-extended gastrin stimulates proliferation via JAK2- and Akt-dependent NF-kappaB activation in Barrett"s oesophageal adenocarcinoma cells.	Glycine	0-7	AKT serine/threonine kinase 1	Homo sapiens	64-67
19055322-7	2008	In this study, a glycine residue was inserted after Tyr536 in the loop within the isolated FMN-binding domain as well as the diflavin reductase domain of P450BM-3, a position equivalent to Gly141 in human CPR.	Glycine	17-24	cytochrome p450 oxidoreductase	Homo sapiens	205-208
18782614-6	2008	MDR1 and PepT1 function was investigated using talinolol and Gly-Sar transport, respectively.	Glycine	61-64	solute carrier family 15 member 1	Homo sapiens	9-14
18782614-12	2008	PepT1 mRNA levels showed significant correlation to the uptake ratio and net active uptake of Gly-Sar.	Glycine	94-97	solute carrier family 15 member 1	Homo sapiens	0-5
18771702-0	2008	Glycine-extended gastrin stimulates proliferation via JAK2- and Akt-dependent NF-kappaB activation in Barrett"s oesophageal adenocarcinoma cells.	Glycine	0-7	nuclear factor kappa B subunit 1	Homo sapiens	78-87
18930730-4	2008	Our data demonstrate that glycine treatment in lean mice suppressed TNF-alpha transcriptional expression in fat tissue, and serum protein levels of IL-6 were suppressed, while adiponectin levels were increased.	Glycine	26-33	tumor necrosis factor	Mus musculus	68-77
19026641-6	2008	The double-glycine motif, which is conserved in the Arf family, only occurs in Rab28 and Rab7B of the Rab family, and may have a profound effect on their catalytic activities.	Glycine	11-18	RAB28, member RAS oncogene family	Homo sapiens	79-84
19026641-6	2008	The double-glycine motif, which is conserved in the Arf family, only occurs in Rab28 and Rab7B of the Rab family, and may have a profound effect on their catalytic activities.	Glycine	11-18	RAB28, member RAS oncogene family	Homo sapiens	79-82
18930730-4	2008	Our data demonstrate that glycine treatment in lean mice suppressed TNF-alpha transcriptional expression in fat tissue, and serum protein levels of IL-6 were suppressed, while adiponectin levels were increased.	Glycine	26-33	interleukin 6	Mus musculus	148-152
18930730-5	2008	In MSG/Ob mice, glycine suppressed TNF-alpha and IL-6 gene expression in fat tissue and significantly reduced protein levels of IL-6, resistin and leptin.	Glycine	16-23	tumor necrosis factor	Mus musculus	35-44
18930730-5	2008	In MSG/Ob mice, glycine suppressed TNF-alpha and IL-6 gene expression in fat tissue and significantly reduced protein levels of IL-6, resistin and leptin.	Glycine	16-23	interleukin 6	Mus musculus	49-53
18930730-5	2008	In MSG/Ob mice, glycine suppressed TNF-alpha and IL-6 gene expression in fat tissue and significantly reduced protein levels of IL-6, resistin and leptin.	Glycine	16-23	interleukin 6	Mus musculus	128-132
18778746-11	2008	Together, these results suggest PKCalpha to be a crucial factor in the regulation of glycine transport in C6 cells.	Glycine	85-92	protein kinase C alpha	Homo sapiens	32-40
19396385-3	2008	FMRP has been shown to use its arginine-glycine-glycine rich region (RGG box) to bind to messenger RNAs that form G quadruplex structures.	Glycine	40-47	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
19396385-3	2008	FMRP has been shown to use its arginine-glycine-glycine rich region (RGG box) to bind to messenger RNAs that form G quadruplex structures.	Glycine	48-55	fragile X messenger ribonucleoprotein 1	Homo sapiens	0-4
18778746-2	2008	At synaptic clefts, the concentration of glycine is tightly regulated by the uptake of glycine released from nerve terminals into glial cells by the transporter GLYT1.	Glycine	41-48	solute carrier family 6 member 9	Homo sapiens	161-166
18778746-2	2008	At synaptic clefts, the concentration of glycine is tightly regulated by the uptake of glycine released from nerve terminals into glial cells by the transporter GLYT1.	Glycine	87-94	solute carrier family 6 member 9	Homo sapiens	161-166
18778746-5	2008	In this study, we attempted to make clear the mechanism of the phorbol 12-myristate 13-acetate (PMA)-suppressed uptake of glycine in C6 glioma cells which have the native expression of GLYT1.	Glycine	122-129	solute carrier family 6 member 9	Homo sapiens	185-190
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	solute carrier family 6 member 9	Homo sapiens	37-42
19005060-3	2008	We synthesized modified Abeta peptides, substituting glycine for leucine residues within the GxxxG repeat motif (GSL peptides).	Glycine	53-60	amyloid beta precursor protein	Homo sapiens	24-29
18805436-6	2008	Forebrain synaptic glycine and d-serine levels are regulated by the Glycine Transporter-1 (GlyT1) and the arginine-serine-cysteine transporter-1 (Asc-1), respectively; in addition to D-serine metabolism by D-Amino Acid Oxidase (DAAO).	Glycine	19-26	solute carrier family 6 member 9	Homo sapiens	68-89
18805436-6	2008	Forebrain synaptic glycine and d-serine levels are regulated by the Glycine Transporter-1 (GlyT1) and the arginine-serine-cysteine transporter-1 (Asc-1), respectively; in addition to D-serine metabolism by D-Amino Acid Oxidase (DAAO).	Glycine	19-26	solute carrier family 6 member 9	Homo sapiens	91-96
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	64-71	solute carrier family 6 member 9	Homo sapiens	37-42
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	solute carrier family 6 member 9	Homo sapiens	37-42
19001664-5	2008	However, through residues phenylalanine 78 and glycine 71, Cripto enriched Nodal at the limiting membrane of early endosomes.	Glycine	47-54	teratocarcinoma-derived growth factor 1	Homo sapiens	59-65
18932277-8	2008	Release of the alkaline phosphatase and aspartate aminotransferase was also blocked significantly in the group fed glycine.	Glycine	115-122	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	40-66
18553216-4	2008	Electrophysiological recordings indicated that 10 muM glycine depolarized rods and activated voltage-gated Ca(2+) channels in the neurons.	Glycine	54-61	latexin	Homo sapiens	50-53
18564064-7	2008	Exposure of MCs to RGD (Arg-Gly-Asp) peptide led to abrogation of the anti-apoptotic effect of uPA, which implies involvement of integrins in this process.	Glycine	28-31	plasminogen activator, urokinase	Homo sapiens	95-98
18644781-12	2008	We identified several residues that are critical for virion formation, most notably a central glycine residue at position 10 of TMS1.	Glycine	94-101	PYD and CARD domain containing	Homo sapiens	128-132
18925969-5	2008	A missense mutation (T to G) was identified at the position of nt 341 in one PRNP allele, leading to a change from glycine (Gly) to valine (Val) at codon 114.	Glycine	115-122	prion protein	Homo sapiens	77-81
18925969-5	2008	A missense mutation (T to G) was identified at the position of nt 341 in one PRNP allele, leading to a change from glycine (Gly) to valine (Val) at codon 114.	Glycine	124-127	prion protein	Homo sapiens	77-81
18805008-1	2008	Several novel classes of potent and small amide-type inhibitors of glycine transport (GlyT1) were developed through sequential simplification of a benzodiazepinone-lead structure identified from a high-throughput screening.	Glycine	67-74	solute carrier family 6 member 9	Homo sapiens	86-91
19082310-11	2008	The genetic analysis of tumoral DNA revealed point mutations in two different genes: the wild type CAA at codon 61 of N-RAS mutated to CAT, replacing glycine by histidine (G61H) and the normal GCC sequence at codon 623 of the TSHR gene was replaced by TCC, changing the alanine by serine (A623S).	Glycine	150-157	catalase	Homo sapiens	135-138
18669635-4	2008	Rodent embryonic fibroblasts adhered to PF1 and deletion fragments, and, when cells were plated on fibrillin-1 or fibronectin Arg-Gly-Asp cell-binding fragments, cells showed heparin-dependent spreading and focal contact formation in response to soluble PF1.	Glycine	130-133	fibronectin 1	Homo sapiens	114-125
18619974-9	2008	Despite mimetic substitutions, including a glycine-to-(d)-proline change, the gp120 conformation induced by CD4M47 was as close or closer to the conformation induced by CD4 as the one induced by the parent CD4M33.	Glycine	43-50	CD4 molecule	Homo sapiens	108-111
18692283-9	2008	In these settings, glycine administration prevented the elevation of serum TNF-alpha levels and liver TNF-alpha mRNA expression.	Glycine	19-26	tumor necrosis factor	Rattus norvegicus	75-84
18800818-3	2008	However, when the peptide Arg-Gly-Asp (RGD) was introduced into ES-2, the modified ES-2 showed significant antitumor results in animal models.	Glycine	30-33	ess-2 splicing factor homolog	Homo sapiens	64-68
18800818-3	2008	However, when the peptide Arg-Gly-Asp (RGD) was introduced into ES-2, the modified ES-2 showed significant antitumor results in animal models.	Glycine	30-33	ess-2 splicing factor homolog	Homo sapiens	83-87
18692283-9	2008	In these settings, glycine administration prevented the elevation of serum TNF-alpha levels and liver TNF-alpha mRNA expression.	Glycine	19-26	tumor necrosis factor	Rattus norvegicus	102-111
18635641-4	2008	NR1/NR2C receptors activated by a maximally effective concentration of glutamate and glycine had two main conductance levels of 45 pS and 28 pS when the extracellular Ca(2+) concentration was 0.5 mm and the holding potential was -80 mV.	Glycine	85-92	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-3
18779583-1	2008	Canonical NMDA receptors assemble from two glycine-binding NR1 subunits with two glutamate-binding NR2 subunits to form glutamate-gated excitatory receptors that mediate synaptic transmission and plasticity.	Glycine	43-50	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	59-62
18715895-2	2008	In homozygous GlyT1 mutants, irrigating brain ventricles with glycine-free solution rescues normal swimming.	Glycine	62-69	solute carrier family 6 member 9	Danio rerio	14-19
18715895-4	2008	These experiments are consistent with previous studies that demonstrate regulation of global glycine levels in the CNS as a primary function of GlyT1.	Glycine	93-100	solute carrier family 6 member 9	Danio rerio	144-149
18384083-7	2008	Thus, here, we have determined the crystal structure of CaM complexed with the 25-residue CaMBD peptide without the glycine linker at a resolution of 2.1 A.	Glycine	116-123	calmodulin 1	Homo sapiens	56-59
18583466-8	2008	Moreover, a case-control study indicated that plasma insulin and C-peptide responses to a lipid load were significantly (P < 0.05) lower in six Gly/Ser than in 12 Gly/Gly carriers.	Glycine	144-147	insulin	Homo sapiens	53-60
18974604-1	2008	D-Serine, an endogenous and obligatory coagonist for the glycine site of the N-methyl-D-aspartate receptor in mammals, is synthesized from L-serine by serine racemase.	Glycine	57-64	serine racemase	Rattus norvegicus	151-166
18767947-5	2008	It results from the fusion of exon 1 to exon 8 of the EGFR gene, which results in a novel glycine at the junction.	Glycine	90-97	epidermal growth factor receptor	Homo sapiens	54-58
18583466-8	2008	Moreover, a case-control study indicated that plasma insulin and C-peptide responses to a lipid load were significantly (P < 0.05) lower in six Gly/Ser than in 12 Gly/Gly carriers.	Glycine	163-166	insulin	Homo sapiens	53-60
18583466-8	2008	Moreover, a case-control study indicated that plasma insulin and C-peptide responses to a lipid load were significantly (P < 0.05) lower in six Gly/Ser than in 12 Gly/Gly carriers.	Glycine	163-166	insulin	Homo sapiens	53-60
18621031-5	2008	In the presence of alanine, glycine uptake was completely blocked by the GlyT1 inhibitors ALX 5407 and sarcosine, suggesting that the high-affinity glycine uptake occurs predominantly via GlyT1.	Glycine	28-35	solute carrier family 6 member 9	Homo sapiens	188-193
18621031-0	2008	The phosphatidylinositol 3-kinase inhibitor LY 294002 inhibits GlyT1-mediated glycine uptake.	Glycine	78-85	solute carrier family 6 member 9	Homo sapiens	63-68
18621031-1	2008	The actions of neurotransmitter glycine are regulated by the Na+/Cl(-) dependent high-affinity glycine transporters, GlyT1 and GlyT2.	Glycine	32-39	solute carrier family 6 member 9	Homo sapiens	117-122
18621031-4	2008	GlyT1 inhibitors ALX 5407 and sarcosine reduced total glycine uptake to 80% whereas the specific GlyT2 inhibitor Org 25543 had no effect.	Glycine	54-61	solute carrier family 6 member 9	Homo sapiens	0-5
18621031-5	2008	In the presence of alanine, glycine uptake was completely blocked by the GlyT1 inhibitors ALX 5407 and sarcosine, suggesting that the high-affinity glycine uptake occurs predominantly via GlyT1.	Glycine	28-35	solute carrier family 6 member 9	Homo sapiens	73-78
18621031-5	2008	In the presence of alanine, glycine uptake was completely blocked by the GlyT1 inhibitors ALX 5407 and sarcosine, suggesting that the high-affinity glycine uptake occurs predominantly via GlyT1.	Glycine	148-155	solute carrier family 6 member 9	Homo sapiens	73-78
18621031-5	2008	In the presence of alanine, glycine uptake was completely blocked by the GlyT1 inhibitors ALX 5407 and sarcosine, suggesting that the high-affinity glycine uptake occurs predominantly via GlyT1.	Glycine	148-155	solute carrier family 6 member 9	Homo sapiens	188-193
18621031-7	2008	LY 294002, a PI3 kinase inhibitor, blocked the GlyT1-mediated glycine uptake with an IC50 value of 81+/-2 microM, whereas another inhibitor wortmannin did not show any effect.	Glycine	62-69	solute carrier family 6 member 9	Homo sapiens	47-52
18621031-11	2008	Kinetic analysis in the presence of LY 294002 demonstrated significant decreases of both Km and Vmax values, suggesting a mechanism of uncompetitive inhibition on GlyT1-mediated glycine uptake.	Glycine	178-185	solute carrier family 6 member 9	Homo sapiens	163-168
17624491-4	2008	The mRNA expression of atrogin-1/MAFbx, proteasome C2 subunit, m-calpain large subunit, and cathepsin B was decreased by glycine in a dose-dependent manner.	Glycine	121-128	cathepsin B	Gallus gallus	92-103
18711142-1	2008	Coassembly of the glycine-binding NMDA receptor subunits NR1 and NR3A results in excitatory glycine receptors of low efficacy.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	57-60
18711142-2	2008	Here, we report that micromolar concentrations of the divalent cation Zn(2+) produce a 10-fold potentiation of NR1/NR3A receptor responses, which resembles that seen upon antagonizing glycine binding to the NR1 subunit.	Glycine	184-191	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	111-114
18711142-2	2008	Here, we report that micromolar concentrations of the divalent cation Zn(2+) produce a 10-fold potentiation of NR1/NR3A receptor responses, which resembles that seen upon antagonizing glycine binding to the NR1 subunit.	Glycine	184-191	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	207-210
18711142-3	2008	Coapplication of both Zn(2+) and NR1 antagonist caused a supralinear potentiation, resulting in a &gt;120-fold increase of glycine-activated currents.	Glycine	123-130	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	33-36
18711142-5	2008	Point mutations in the NR1 and NR3A glycine-binding sites revealed that both the potentiating and agonistic effects of Zn(2+) are mediated by the ligand-binding domain of the NR1 subunit.	Glycine	36-43	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	175-178
18667304-2	2008	This was performed in the following two steps: (1) conversion of the N-terminal glycine residue to an alpha-keto aldehyde by a transamination reaction and (2) condensation of the resulting activated myoglobin with tryptamine analogues by the Pictet-Spengler reaction.	Glycine	80-87	myoglobin	Equus caballus	199-208
18450751-4	2008	Two mutants, E522C/I691C in NR1 (EI) and K487C/N687C in NR2 (KN) were found to exhibit significant glycine- and glutamate-independent activation, respectively, and co-expression of the two subunits produced a constitutively active channel.	Glycine	99-106	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	28-31
18507738-4	2008	p39 and p35 contain localization motifs, such as a second Gly for myristoylation and Lys clusters in the N-terminal p10 region.	Glycine	58-61	S100 calcium binding protein A10	Homo sapiens	116-119
18852529-0	2008	Glycine treatment decreases proinflammatory cytokines and increases interferon-gamma in patients with type 2 diabetes.	Glycine	0-7	interferon gamma	Homo sapiens	68-84
18852529-2	2008	In vitro, glycine reduces tumor necrosis factor (TNF)-alpha secretion and increases interleukin-10 secretion in human monocytes stimulated with lipopolysaccharide.	Glycine	10-17	tumor necrosis factor	Homo sapiens	26-59
18852529-10	2008	These data showed that patients treated with glycine had a significant decrease in A1C and in proinflammatory cytokines and also an important increase of IFN-gamma.	Glycine	45-52	interferon gamma	Homo sapiens	154-163
18507738-4	2008	p39 and p35 contain localization motifs, such as a second Gly for myristoylation and Lys clusters in the N-terminal p10 region.	Glycine	58-61	cyclin dependent kinase 5 regulatory subunit 2	Homo sapiens	0-3
18611046-2	2008	When reactions were carried out in D(2)O, there was a significant incorporation of deuterium specifically into the C(alpha)-H bonds of glycine residues in positions i+1 and i-1 to the Cys residue, indicating a fast reversible H-atom transfer.	Glycine	135-142	protein phosphatase 1 regulatory inhibitor subunit 1A	Homo sapiens	173-176
18554632-1	2008	PURPOSE: Previously we found that the trophinin-binding peptide GWRQ (glycine, tryptophane, arginine, glutamic acid) activated human trophoblastic cells.	Glycine	70-77	trophinin	Homo sapiens	38-47
18456371-3	2008	NEI is produced by cleavage of prepro-MCH that probably takes place at the Lys(129)-Arg(130) and Arg(145)-Arg(146) sites (the glycine residue on the C-terminus of NEI strongly suggests that this peptide is amidated).	Glycine	126-133	pro-melanin concentrating hormone	Homo sapiens	38-41
18670643-4	2008	In patients bearing the FGFR-4 Gly(388) variant, expression of Huntingtin-interacting protein 1 (HIP1), which occurs in more than half of human prostate cancers, also results in FGFR-4 stabilization.	Glycine	31-34	huntingtin interacting protein 1	Homo sapiens	63-95
18670643-4	2008	In patients bearing the FGFR-4 Gly(388) variant, expression of Huntingtin-interacting protein 1 (HIP1), which occurs in more than half of human prostate cancers, also results in FGFR-4 stabilization.	Glycine	31-34	huntingtin interacting protein 1	Homo sapiens	97-101
18628682-1	2008	OBJECTIVES: Vesicle-associated membrane proteins 2 and 3 (VAMP2 and VAMP3) are required for the release of D-serine, a competitive agonist of the neurotransmitter glycine at the glutamatergic N-methyl-D-aspartate receptors.	Glycine	163-170	vesicle associated membrane protein 2	Homo sapiens	58-63
18629001-6	2008	Recombinant NR1 glycine binding protein was used to identify MMP-3 cleavage sites within the extracellular S1 and S2-domains.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	12-15
18629001-6	2008	Recombinant NR1 glycine binding protein was used to identify MMP-3 cleavage sites within the extracellular S1 and S2-domains.	Glycine	16-23	matrix metallopeptidase 3	Homo sapiens	61-66
18565339-9	2008	Consistent with these in vivo experiments, enhanced secretion of IL-10 and inhibited expression of TLR4 and TNF-alpha caused by glycine pretreatment were also observed in LPS-stimulated KCs.	Glycine	128-135	toll-like receptor 4	Mus musculus	99-103
18448590-1	2008	A mutation in the human FXYD2 polypeptide (Na-K-ATPase gamma subunit) that changes a conserved transmembrane glycine to arginine is linked to dominant renal hypomagnesemia.	Glycine	109-116	FXYD domain containing ion transport regulator 2	Homo sapiens	24-29
18565339-0	2008	Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells.	Glycine	0-7	toll-like receptor 4	Mus musculus	68-72
18565339-9	2008	Consistent with these in vivo experiments, enhanced secretion of IL-10 and inhibited expression of TLR4 and TNF-alpha caused by glycine pretreatment were also observed in LPS-stimulated KCs.	Glycine	128-135	tumor necrosis factor	Mus musculus	108-117
18565339-10	2008	NF-kappaB DNA-binding activity was also significantly inhibited by glycine (P &lt; .05, respectively).	Glycine	67-74	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	0-9
18565339-13	2008	The downregulative effect of glycine on the endotoxin signaling pathway and TLR4/NF-kappaB/TNF-alpha may be a novel potential mechanism by which glycine inhibits KC activity.	Glycine	145-152	toll-like receptor 4	Mus musculus	76-80
18565339-13	2008	The downregulative effect of glycine on the endotoxin signaling pathway and TLR4/NF-kappaB/TNF-alpha may be a novel potential mechanism by which glycine inhibits KC activity.	Glycine	145-152	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	81-90
18565339-13	2008	The downregulative effect of glycine on the endotoxin signaling pathway and TLR4/NF-kappaB/TNF-alpha may be a novel potential mechanism by which glycine inhibits KC activity.	Glycine	145-152	tumor necrosis factor	Mus musculus	91-100
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	123-131
18603832-1	2008	Recent studies indicate that an endogenous co-agonist for an N-methyl-D-aspartate (NMDA) receptor-related glycine site, D-serine, is synthesized by serine racemase and is metabolized by D-amino acid oxidase (DAO) and that acute treatment with morphine augments the gene expression of serine racemase and DAO in rat brain.	Glycine	106-113	serine racemase	Rattus norvegicus	148-163
18603832-1	2008	Recent studies indicate that an endogenous co-agonist for an N-methyl-D-aspartate (NMDA) receptor-related glycine site, D-serine, is synthesized by serine racemase and is metabolized by D-amino acid oxidase (DAO) and that acute treatment with morphine augments the gene expression of serine racemase and DAO in rat brain.	Glycine	106-113	D-amino-acid oxidase	Rattus norvegicus	186-206
18603832-1	2008	Recent studies indicate that an endogenous co-agonist for an N-methyl-D-aspartate (NMDA) receptor-related glycine site, D-serine, is synthesized by serine racemase and is metabolized by D-amino acid oxidase (DAO) and that acute treatment with morphine augments the gene expression of serine racemase and DAO in rat brain.	Glycine	106-113	D-amino-acid oxidase	Rattus norvegicus	208-211
18603832-1	2008	Recent studies indicate that an endogenous co-agonist for an N-methyl-D-aspartate (NMDA) receptor-related glycine site, D-serine, is synthesized by serine racemase and is metabolized by D-amino acid oxidase (DAO) and that acute treatment with morphine augments the gene expression of serine racemase and DAO in rat brain.	Glycine	106-113	serine racemase	Rattus norvegicus	284-299
18603832-1	2008	Recent studies indicate that an endogenous co-agonist for an N-methyl-D-aspartate (NMDA) receptor-related glycine site, D-serine, is synthesized by serine racemase and is metabolized by D-amino acid oxidase (DAO) and that acute treatment with morphine augments the gene expression of serine racemase and DAO in rat brain.	Glycine	106-113	D-amino-acid oxidase	Rattus norvegicus	304-307
18577755-2	2008	Recently, in work by Ferreon and Hilser, the energetics associated with Ala and Gly substitutions at a surface exposed proline site were determined calorimetrically by measuring the binding energetics of Sos peptide variants to the C-terminal Src Homology 3 domain of SEM-5.	Glycine	80-83	xylosyltransferase 2	Homo sapiens	204-207
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	48-51	coagulation factor II, thrombin	Homo sapiens	123-131
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	48-51	coagulation factor II, thrombin	Homo sapiens	252-260
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	48-51	coagulation factor II, thrombin	Homo sapiens	262-265
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	123-131
18988464-2	2008	It was concluded that Gly, D-Ser, D-Asn and D-Thr are ligands of NR1-binding core native NMDA-receptor, whereas the chiral modified NR1-binding core is characterized by the aliphatic non-polar amino acids D-Ala, D-Leu, D-Ile and D-Pro as ligands.	Glycine	22-25	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	65-68
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	252-260
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	252-260
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	262-265
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	262-265
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	123-131
18507366-1	2008	D-amino acid oxidase (DAAO) catalyzes the oxidation of D-amino acids including d-serine, a full agonist at the glycine site of the NMDA receptor.	Glycine	111-118	D-amino-acid oxidase	Rattus norvegicus	0-20
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	252-260
18507366-1	2008	D-amino acid oxidase (DAAO) catalyzes the oxidation of D-amino acids including d-serine, a full agonist at the glycine site of the NMDA receptor.	Glycine	111-118	D-amino-acid oxidase	Rattus norvegicus	22-26
18585267-1	2008	By designing and coupling a functional peptide, Gly-Leu-Ala-Cys-Ser-Gly-Phe-Pro-Arg-Gly-Arg-Trp, which could be cleaved by thrombin at the site of Arg-Gly (R-G), to the surface of gold nanoparticles (Au-NPs), we propose a simple spectrofluorometry for thrombin (TRB) in this contribution.	Glycine	68-71	coagulation factor II, thrombin	Homo sapiens	262-265
18326664-6	2008	These results suggest that the adjacent glycines 1885 and 1886, located in the divergent region 3, are critical for the function and regulation of RyR2.	Glycine	40-48	ryanodine receptor 2	Homo sapiens	147-151
18499099-2	2008	A treatment option to improve the micro- and macro-complications in type 2 diabetes is the use of glycine, which has been demonstrated previously to increase the expression of anti-inflammatory cytokine IL-10 in monocytes and down-regulate the expression of TNF-alpha in monocytes and Kupffer cells.	Glycine	98-105	interleukin 10	Mus musculus	203-208
18499099-2	2008	A treatment option to improve the micro- and macro-complications in type 2 diabetes is the use of glycine, which has been demonstrated previously to increase the expression of anti-inflammatory cytokine IL-10 in monocytes and down-regulate the expression of TNF-alpha in monocytes and Kupffer cells.	Glycine	98-105	tumor necrosis factor	Mus musculus	258-267
18499099-9	2008	We demonstrated that when 3T3-L1 cells were treated with glycine, IL-6, resistin and TNF-alpha mRNA expression was decreased, but surprisingly adiponectin and PPAR-gamma were up-regulated.	Glycine	57-64	interleukin 6	Mus musculus	66-70
18499099-9	2008	We demonstrated that when 3T3-L1 cells were treated with glycine, IL-6, resistin and TNF-alpha mRNA expression was decreased, but surprisingly adiponectin and PPAR-gamma were up-regulated.	Glycine	57-64	tumor necrosis factor	Mus musculus	85-94
18342011-3	2008	Disease-causing mutation in Nramp1 occurring at glycine 169 located within the fourth transmembrane domain (TM4) suggests functional importance of this domain.	Glycine	48-55	solute carrier family 11 member 1	Homo sapiens	28-34
18524949-7	2008	The active site Cys-X(5)-Arg (CX(5)R) sequence of Ci-VSP differs with that of PTEN only at amino acid 365 where a glycine residue in Ci-VSP is replaced by an alanine in PTEN.	Glycine	114-121	voltage-sensor containing phosphatase	Ciona intestinalis	53-56
18524949-7	2008	The active site Cys-X(5)-Arg (CX(5)R) sequence of Ci-VSP differs with that of PTEN only at amino acid 365 where a glycine residue in Ci-VSP is replaced by an alanine in PTEN.	Glycine	114-121	voltage-sensor containing phosphatase	Ciona intestinalis	136-139
18490713-8	2008	We delineated two distinct release pathways: the well-known caspase-1 cascade mediating release of processed IL-1beta that was selectively blocked by inhibition of caspase-1 or panx1, and a calcium-independent, caspase-1/panx1-independent release of pro-IL-1beta that was selectively blocked by glycine.	Glycine	295-302	interleukin 1 beta	Mus musculus	109-117
18422998-4	2008	Plasma fibronectin (Fn), a ligand for alpha4beta1, could link SS RBCs to monocytes, as peptides derived from both the Arg-Gly-Asp-Ser (RGDS) and CS-1 site in Fn disrupted the reticulocyte/monocyte interaction.	Glycine	122-125	fibronectin 1	Homo sapiens	7-18
18422998-4	2008	Plasma fibronectin (Fn), a ligand for alpha4beta1, could link SS RBCs to monocytes, as peptides derived from both the Arg-Gly-Asp-Ser (RGDS) and CS-1 site in Fn disrupted the reticulocyte/monocyte interaction.	Glycine	122-125	fibronectin 1	Homo sapiens	20-22
18436238-8	2008	Rather, we have discovered that the carboxy-terminal glycine-rich region of the NF-kappaB p50 homodimer is involved in mediating high-affinity binding of I kappaB zeta and NF-kappaB p50.	Glycine	53-60	nuclear factor kappa B subunit 1	Homo sapiens	80-89
18380773-1	2008	The sequence of human leukocyte antigen (HLA)-A*3314 is identical to that of HLA-A*330301 except for a single-nucleotide substitution at codon 49 (GCG--&gt;GGG) resulting in an amino acid change from Ala to Gly.	Glycine	207-210	major histocompatibility complex, class I, A	Homo sapiens	22-47
18380773-1	2008	The sequence of human leukocyte antigen (HLA)-A*3314 is identical to that of HLA-A*330301 except for a single-nucleotide substitution at codon 49 (GCG--&gt;GGG) resulting in an amino acid change from Ala to Gly.	Glycine	207-210	major histocompatibility complex, class I, A	Homo sapiens	77-82
18094991-0	2008	hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3.	Glycine	50-53	solute carrier family 15 member 1	Homo sapiens	0-6
18094991-10	2008	Surprisingly, the results indicate that Gly-Sar uptake and transport in Calu-3 cells are hPEPT1-mediated rather than hPEPT2-mediated.	Glycine	40-43	solute carrier family 15 member 1	Homo sapiens	89-95
18436238-8	2008	Rather, we have discovered that the carboxy-terminal glycine-rich region of the NF-kappaB p50 homodimer is involved in mediating high-affinity binding of I kappaB zeta and NF-kappaB p50.	Glycine	53-60	nuclear factor kappa B subunit 1	Homo sapiens	90-93
18436238-8	2008	Rather, we have discovered that the carboxy-terminal glycine-rich region of the NF-kappaB p50 homodimer is involved in mediating high-affinity binding of I kappaB zeta and NF-kappaB p50.	Glycine	53-60	nuclear factor kappa B subunit 1	Homo sapiens	172-181
18436238-8	2008	Rather, we have discovered that the carboxy-terminal glycine-rich region of the NF-kappaB p50 homodimer is involved in mediating high-affinity binding of I kappaB zeta and NF-kappaB p50.	Glycine	53-60	nuclear factor kappa B subunit 1	Homo sapiens	182-185
19055014-4	2008	Both VIP and SS were found to amplify the inhibitory action of GABA and glycine.	Glycine	72-79	vasoactive intestinal peptide	Felis catus	5-8
18475188-10	2008	RESULTS: Compared with vehicle controls, glycine-treated graft muscularis expressed a significant alleviation in mRNA peak expression for IL-6, IL-1beta, ICAM-1, MCP-1, TNFalpha, COX-2, and iNOS.	Glycine	41-48	interleukin 6	Rattus norvegicus	138-142
18475188-10	2008	RESULTS: Compared with vehicle controls, glycine-treated graft muscularis expressed a significant alleviation in mRNA peak expression for IL-6, IL-1beta, ICAM-1, MCP-1, TNFalpha, COX-2, and iNOS.	Glycine	41-48	interleukin 1 beta	Rattus norvegicus	144-152
18475188-10	2008	RESULTS: Compared with vehicle controls, glycine-treated graft muscularis expressed a significant alleviation in mRNA peak expression for IL-6, IL-1beta, ICAM-1, MCP-1, TNFalpha, COX-2, and iNOS.	Glycine	41-48	mast cell protease 1-like 1	Rattus norvegicus	162-167
18475188-10	2008	RESULTS: Compared with vehicle controls, glycine-treated graft muscularis expressed a significant alleviation in mRNA peak expression for IL-6, IL-1beta, ICAM-1, MCP-1, TNFalpha, COX-2, and iNOS.	Glycine	41-48	tumor necrosis factor	Rattus norvegicus	169-177
18475188-10	2008	RESULTS: Compared with vehicle controls, glycine-treated graft muscularis expressed a significant alleviation in mRNA peak expression for IL-6, IL-1beta, ICAM-1, MCP-1, TNFalpha, COX-2, and iNOS.	Glycine	41-48	nitric oxide synthase 2	Rattus norvegicus	190-194
18336632-7	2008	Ethanol reduced maximal transport capacity (I(max)) of hPepT1 for Gly-Sar without affecting Gly-Sar binding affinity (K(0.5) and Hill coefficient).	Glycine	66-69	solute carrier family 15 member 1	Homo sapiens	55-61
18480275-7	2008	Consistently, TNFalpha and IL-1beta enhanced AMPA- or NMDA-induced currents, and IL-1beta and IL-6 suppressed GABA- and glycine-induced currents.	Glycine	120-127	interleukin 1 beta	Homo sapiens	81-89
18480275-7	2008	Consistently, TNFalpha and IL-1beta enhanced AMPA- or NMDA-induced currents, and IL-1beta and IL-6 suppressed GABA- and glycine-induced currents.	Glycine	120-127	interleukin 6	Homo sapiens	94-98
18396105-9	2008	INTERPRETATION: The Gly290Ala and Gly298Ser mutations are located in the glycine-rich domain of TDP-43, which regulates gene expression and mediates protein-protein interactions such as those with heterogeneous ribonucleoproteins.	Glycine	73-80	TAR DNA binding protein	Homo sapiens	96-102
18421157-2	2008	The Neh2 domain of Nrf2 interacts with Keap1 at the bottom region of the Kelch/beta-propeller domain which is formed by double-glycine repeat and C-terminal region domains (Keap1-DC).	Glycine	127-134	NFE2 like bZIP transcription factor 2	Homo sapiens	19-23
18421157-2	2008	The Neh2 domain of Nrf2 interacts with Keap1 at the bottom region of the Kelch/beta-propeller domain which is formed by double-glycine repeat and C-terminal region domains (Keap1-DC).	Glycine	127-134	kelch like ECH associated protein 1	Homo sapiens	39-44
18421157-2	2008	The Neh2 domain of Nrf2 interacts with Keap1 at the bottom region of the Kelch/beta-propeller domain which is formed by double-glycine repeat and C-terminal region domains (Keap1-DC).	Glycine	127-134	kelch like ECH associated protein 1	Homo sapiens	173-178
18243325-2	2008	The fourth transmembrane domain (TM4) housing the disease-causing mutations both in Nramp1 and Nramp2 at the conserved two adjacent glycine residues, was implicated to serve an important biological function.	Glycine	132-139	solute carrier family 11 member 2	Rattus norvegicus	95-101
18285453-0	2008	A glycine-arginine domain in control of the human MRE11 DNA repair protein.	Glycine	2-9	MRE11 homolog, double strand break repair nuclease	Homo sapiens	50-55
18285453-2	2008	Human MRE11 bears a glycine-arginine-rich (GAR) motif that is conserved among multicellular eukaryotic species.	Glycine	20-27	MRE11 homolog, double strand break repair nuclease	Homo sapiens	6-11
18268017-4	2008	By generating a series of chimeric and point mutants of p38alpha and p38beta, we found two amino acid residues (Asp(145) and Leu(156) in p38alpha, Gly(145) and Val(156) in p38beta) that determine the distinct subcellular locations of p38alpha-PRAK and p38beta-PRAK.	Glycine	147-150	mitogen-activated protein kinase 11	Mus musculus	69-76
18502619-3	2008	The PLM sample investigated here consists of a high lipid/peptide molar ratio (25:1) with one glycine residue in each helix enriched to &lt;40% (17)O; thus, this is a very dilute 17O-sample and is the most dilute 17O-membrane protein to date to be characterized by solid-state 17O NMR spectroscopy.	Glycine	94-101	FXYD domain containing ion transport regulator 1	Homo sapiens	4-7
18268017-4	2008	By generating a series of chimeric and point mutants of p38alpha and p38beta, we found two amino acid residues (Asp(145) and Leu(156) in p38alpha, Gly(145) and Val(156) in p38beta) that determine the distinct subcellular locations of p38alpha-PRAK and p38beta-PRAK.	Glycine	147-150	mitogen-activated protein kinase 11	Mus musculus	172-179
18268017-4	2008	By generating a series of chimeric and point mutants of p38alpha and p38beta, we found two amino acid residues (Asp(145) and Leu(156) in p38alpha, Gly(145) and Val(156) in p38beta) that determine the distinct subcellular locations of p38alpha-PRAK and p38beta-PRAK.	Glycine	147-150	mitogen-activated protein kinase 11	Mus musculus	172-179
17588735-0	2008	Cell death signal by glycine- and proline-rich plant glycoprotein is transferred from cytochrome c and nuclear factor kappa B to caspase 3 in Hep3B cells.	Glycine	21-28	cytochrome c, somatic	Homo sapiens	86-98
18331838-7	2008	Recombinant TTLL10 incorporated glycine into recombinant NAP1 in vitro.	Glycine	32-39	tubulin tyrosine ligase like 10	Homo sapiens	12-18
18331838-7	2008	Recombinant TTLL10 incorporated glycine into recombinant NAP1 in vitro.	Glycine	32-39	nucleosome assembly protein 1 like 1	Homo sapiens	57-61
18327570-4	2008	To demonstrate its utility, MPH was ligated to an single-chain variable fragment (scFv), known as A1E, against a white spot syndrome virus (WSSV) with the insertion of a [-(Gly-Ser)(5)-] linker peptide.	Glycine	173-176	immunglobulin heavy chain variable region	Homo sapiens	82-86
18379051-6	2008	In oocytes expressing glycine or 5-HT3A receptors, quercetin- or its glycosides-induced inhibitions on glycine- (IGly) and 5-HT-induced current (I5-HT) were dose-dependent and reversible.	Glycine	103-110	5-hydroxytryptamine receptor 3A	Homo sapiens	33-39
18230692-0	2008	Proteasome-dependent pharmacological rescue of cystic fibrosis transmembrane conductance regulator revealed by mutation of glycine 622.	Glycine	123-130	CF transmembrane conductance regulator	Homo sapiens	47-98
18165705-9	2008	Upon further analysis we found that a glycine-alaninerich region at the N-terminal end of OSBP works with the PH domain to control cholesterol binding without affecting 25-hydroxycholesterol binding.	Glycine	38-45	oxysterol binding protein	Homo sapiens	90-94
18029081-1	2008	The N-terminal glycine of the A-chain in insulin is reported to be one of the residues that binds to the insulin receptor.	Glycine	15-22	insulin	Homo sapiens	41-48
18270170-8	2008	Na(V)1.4 channels with one CaM fused to the CT by variable length glycine linkers exhibit CaM modulation of gating only with linker lengths that allowed CaM to reach IQ region.	Glycine	66-73	calmodulin 1	Homo sapiens	27-30
18270170-8	2008	Na(V)1.4 channels with one CaM fused to the CT by variable length glycine linkers exhibit CaM modulation of gating only with linker lengths that allowed CaM to reach IQ region.	Glycine	66-73	calmodulin 1	Homo sapiens	90-93
18270170-8	2008	Na(V)1.4 channels with one CaM fused to the CT by variable length glycine linkers exhibit CaM modulation of gating only with linker lengths that allowed CaM to reach IQ region.	Glycine	66-73	calmodulin 1	Homo sapiens	90-93
18316066-5	2008	Vulnerability of the differentiated cells towards the oxidizer, arsenite, and the excitotoxic glutamate/glycine is demonstrated by the dose-dependent cytotoxic effects of these agents on cell viability and activation of caspase 3/7.	Glycine	104-111	caspase 3	Homo sapiens	220-229
18391415-2	2008	The beta-propeller/Kelch domain of Keap1, which is formed by the double-glycine repeat and C-terminal region domains (Keap1-DC), interacts directly with the Neh2 domain of Nrf2.	Glycine	72-79	kelch like ECH associated protein 1	Homo sapiens	35-40
18391415-2	2008	The beta-propeller/Kelch domain of Keap1, which is formed by the double-glycine repeat and C-terminal region domains (Keap1-DC), interacts directly with the Neh2 domain of Nrf2.	Glycine	72-79	kelch like ECH associated protein 1	Homo sapiens	118-123
18391415-2	2008	The beta-propeller/Kelch domain of Keap1, which is formed by the double-glycine repeat and C-terminal region domains (Keap1-DC), interacts directly with the Neh2 domain of Nrf2.	Glycine	72-79	NFE2 like bZIP transcription factor 2	Homo sapiens	172-176
18267362-2	2008	The in vitro aldose reductase inhibitory activity of the prepared compounds is higher than that of the respective glycine derivatives.	Glycine	114-121	aldo-keto reductase family 1 member B	Homo sapiens	13-29
18042364-6	2008	This region of fibronectin contains the Arg-Gly-Asp sequence recognized by alpha5beta1 integrin, but deletion of that sequence does not prevent TSG-6 binding, and TSG-6 does not inhibit cell adhesion on fibronectin substrates mediated by this integrin.	Glycine	44-47	fibronectin 1	Homo sapiens	15-26
17588735-0	2008	Cell death signal by glycine- and proline-rich plant glycoprotein is transferred from cytochrome c and nuclear factor kappa B to caspase 3 in Hep3B cells.	Glycine	21-28	caspase 3	Homo sapiens	129-138
18036205-11	2008	Mutagenesis of a conserved glutathione-binding glycine in the ROXY1 protein indicates that CC-type GRXs need to interact with glutathione to catalyze essential biosynthetic reactions.	Glycine	47-54	Thioredoxin superfamily protein	Arabidopsis thaliana	62-67
17949855-0	2008	Glycine residues G338 and G342 are important determinants for serotonin transporter dimerisation and cell surface expression.	Glycine	0-7	solute carrier family 6 member 4	Homo sapiens	62-83
18589597-11	2008	And the air pollutants, PM4, SO2 and CO, interacted with the Gly/Gly genotype at the 16th locus of beta2-AR gene or the DD genotype of ACE gene maybe increases the risk for asthma in children.	Glycine	61-64	angiotensin I converting enzyme	Homo sapiens	135-138
18048007-0	2008	Glycine modulates synaptic NR2A- and NR2B-containing NMDA receptor-mediated responses in the rat visual cortex.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	27-31
18215067-9	2008	However, drugs that exploit the unique structural features of GO may ultimately prove to be useful for decreasing glycolate and glyoxylate levels in primary hyperoxaluria type 1 patients who have the inability to convert peroxisomal glyoxylate to glycine.	Glycine	247-254	hydroxyacid oxidase 2	Homo sapiens	62-64
18197709-4	2008	One successful approach that overcomes these difficulties is the use of poly-N-substituted glycines, or peptoids, to mimic SP-C.	Glycine	91-99	surfactant protein C	Homo sapiens	123-127
17972239-5	2008	Insulin resistance was estimated by HOMA-IR, insulin sensitivity using ISI(gly) and ISI(Stumvoll) indexes, insulin secretion by first (1stPH est) and second phase (2ndPH est) estimates.	Glycine	75-78	insulin	Homo sapiens	0-7
18289097-1	2008	Myristoyl-CoA:Protein N-myristoyltranferase (NMT) is a cytosolic monomeric enzyme which catalyses the transfer of a rare fatty acid, myristate from myristoyl-CoA to the N-terminal glycine residue of a variety of eukaryotic and viral proteins.	Glycine	180-187	N-myristoyltransferase 1	Homo sapiens	22-43
18289097-1	2008	Myristoyl-CoA:Protein N-myristoyltranferase (NMT) is a cytosolic monomeric enzyme which catalyses the transfer of a rare fatty acid, myristate from myristoyl-CoA to the N-terminal glycine residue of a variety of eukaryotic and viral proteins.	Glycine	180-187	N-myristoyltransferase 1	Homo sapiens	45-48
18060852-3	2008	In addition, our construct has the added benefit of yielding a purified CBS which only contains one extra glycine amino acid residue at the N-terminus.	Glycine	106-124	cystathionine beta-synthase	Homo sapiens	72-75
17522628-4	2008	Moreover, endogenously elevating the glycine concentration with the GlyT1 antagonists facilitated NMDA receptor-dependent long-term potentiation induction, and elicited a strychnine-sensitive chloride current.	Glycine	37-44	solute carrier family 6 member 9	Homo sapiens	68-73
18048007-6	2008	Moreover, Zn2+, an NR2A-NMDA-R antagonist, also reduced NMDA-mediated mEPSCs and glycine with Zn2+ enhanced the NMDA-mediated mEPSCs.	Glycine	81-88	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	19-23
18048007-7	2008	Our data indicate that the glycine binding site of synaptic NR2A-containing and NR2B-containing NMDA-Rs does not saturate and that glycine may act as a modulator of NMDA-R-mediated transmission in layer II/III pyramidal neurons of the rat visual cortex.	Glycine	27-34	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	60-64
18215303-8	2008	Two frameshifts, in the cox3 and nad6 genes, were not corrected by RNA editing, but rather possessed identical shift sites marked by the extremely rare tryptophan codon (UGG) followed by the common glycine codon (GGA) in the +1 frame.	Glycine	198-205	NAD6	Aphrocallistes vastus	33-37
18068304-2	2008	These ligand-gated ion channels are heteromultimers composed of NR1 and NR2 subunits activated by glycine and glutamate.	Glycine	98-105	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	64-67
17971454-5	2007	In this study, we examined the roles of the putative catalytic motif and the conserved glycine for PAP1 activity by a mutational analysis.	Glycine	87-94	polynucleotide adenylyltransferase PAP1	Saccharomyces cerevisiae S288C	99-103
17986381-3	2008	Here we report that cytochrome c catalyzes the synthesis of N-arachidonoyl glycine (NAGly) from arachidonoyl coenzyme A and glycine in the presence of hydrogen peroxide.	Glycine	75-82	cytochrome c, somatic	Homo sapiens	20-32
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	232-239	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	37-40
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	232-239	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	179-182
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	232-239	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	179-182
18039857-2	2008	A novel regulatory mechanism to control c-Src function that has recently been identified involves the C-terminal amino acid sequence Gly-Glu-Asn-Leu (GENL) of c-Src as ligand for PDZ domains.	Glycine	133-136	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	40-45
18039857-2	2008	A novel regulatory mechanism to control c-Src function that has recently been identified involves the C-terminal amino acid sequence Gly-Glu-Asn-Leu (GENL) of c-Src as ligand for PDZ domains.	Glycine	133-136	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	159-164
17597258-4	2008	The glycine-evoked release of [3H]GABA was exocytotic from synaptosomes but GAT1 carrier-mediated from gliosomes.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	Mus musculus	76-80
18039657-5	2008	Mutations of two Gly residues at positions 776 and 778 in this loop dramatically increase ErbB2 catalytic activity.	Glycine	17-20	erb-b2 receptor tyrosine kinase 2	Homo sapiens	90-95
18046452-2	2008	We show that Mex67-Mtr2 through the same surface that recruits pre-60S particles interacts with the Nup84 complex, a structural module of the nuclear pore complex devoid of Phe-Gly domains.	Glycine	177-180	cap methyltransferase 2	Homo sapiens	19-23
18046452-2	2008	We show that Mex67-Mtr2 through the same surface that recruits pre-60S particles interacts with the Nup84 complex, a structural module of the nuclear pore complex devoid of Phe-Gly domains.	Glycine	177-180	nucleoporin 107	Homo sapiens	100-105
17582620-1	2008	Glycine transporter (GlyT)-1 plays a pivotal role in maintaining the glycine level at the glutamatergic synapse.	Glycine	69-76	solute carrier family 6 member 9	Homo sapiens	0-28
17959602-1	2008	N-Methyl-D-aspartate (NMDA) receptors are tetrameric protein complexes composed of the glycine-binding NR1 subunit with a glutamate-binding NR2 and/or glycine-binding NR3 subunit.	Glycine	87-94	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	103-106
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	150-157	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	37-40
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	150-157	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	179-182
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	150-157	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	179-182
17924589-7	2008	When combinations of the two polymorphisms were considered, patients who had T/T in the HTR2A gene and encoded Ser/Ser or Ser/Gly from DRD3 gene had a higher propensity to non-responsiveness compared to other subjects (OR = 3.57, 95%CI = 1.10-11.62, p = 0.039).	Glycine	126-129	5-hydroxytryptamine receptor 2A	Homo sapiens	88-93
17911111-4	2007	Although replacement of the 18 endogenous cysteines of CFTR with Ser or Ala yields a Cys-less mutant that does not mature at 37 degrees C, we found that maturation could be restored if Val(510) was changed to Ala, Cys, Ser, Thr, Gly, Ala, or Asp.	Glycine	229-232	CF transmembrane conductance regulator	Homo sapiens	55-59
17827792-13	2007	Sequence analysis of the TR beta gene was performed with informed consent, and this revealed a novel heterozygous mutation at codon 347 resulting in a GGG (glycine) to GCG (alanine) substitution (G347A).	Glycine	156-163	T cell receptor beta locus	Homo sapiens	25-32
17973469-5	2007	Nuclear magnetic resonance (NMR), modeling, and docking studies indicate that in solution the peptide exhibits a beta-turn at residues Trp-Asp-Gly-Val and possibly binds to the hydrophobic channel of sPLA2.	Glycine	143-146	phospholipase A2 group X	Homo sapiens	200-205
17878166-9	2007	The Arg(26) in SCA3, replacing the Gly(26) in SCA1, is predicted to cause structural changes that result in a significantly reduced volume for the internal hydrophobic cavity in SCA3.	Glycine	35-38	caspase 3	Homo sapiens	46-50
17996689-6	2007	A combination of b-LF 0.1 mg/mouse/day and glycine 20 or 50 mg/mouse/day counteracted the zymosan-induced ear swelling synergistically and enhanced the decrease in the number of TNF-alpha producing spleen cells of the individual components.	Glycine	43-50	tumor necrosis factor	Mus musculus	178-187
17996689-11	2007	A combination of glycine and lactoferrin demonstrated a synergistic anti-inflammatory effect on zymosan-induced skin inflammation and an enhanced decrease in the number of TNF-alpha producing spleen cells compared to the effect of the single components.	Glycine	17-24	tumor necrosis factor	Mus musculus	172-181
17878266-0	2007	The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors.	Glycine	93-100	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	31-34
17878266-1	2007	The N-methyl-D-aspartate (NMDA) subtype of ionotropic glutamate receptors (iGluRs) is a tetrameric protein composed of homologous NR1 and NR2 subunits, which require the binding of glycine and glutamate, respectively, for efficient channel gating.	Glycine	181-188	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	130-133
17878266-7	2007	Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	30-34
17878266-7	2007	Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	110-113
17878266-7	2007	Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	114-118
17878266-7	2007	Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	123-126
17878266-8	2007	Together, these data show that the NTDs of both the NR1 and NR2 subunits determine allosteric inhibition and glycine potency but are not required for NMDA receptor assembly.	Glycine	109-116	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	52-55
17698851-6	2007	The helix-helix packing is unusual, with Gly(19) and Gly(20) pointing to the outside of the helical bundle, facilitating potential interaction with other transmembrane proteins, thus providing a structural basis for the modulatory effect of PLM on the Na(+)/K(+)-ATPase.	Glycine	41-44	FXYD domain containing ion transport regulator 1	Homo sapiens	241-244
17698851-6	2007	The helix-helix packing is unusual, with Gly(19) and Gly(20) pointing to the outside of the helical bundle, facilitating potential interaction with other transmembrane proteins, thus providing a structural basis for the modulatory effect of PLM on the Na(+)/K(+)-ATPase.	Glycine	53-56	FXYD domain containing ion transport regulator 1	Homo sapiens	241-244
18073551-3	2007	The authors show that xenon and isoflurane compete for the binding of the coagonist glycine on the NMDA receptor NR1 subunit.	Glycine	84-91	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	113-116
17785459-6	2007	On the contrary, residual agonism of the hPRL variants was found to be inversely correlated to their thermodynamic stability, which was altered by all the Gly(129) mutations but not by those involving the N terminus.	Glycine	155-158	prolactin	Homo sapiens	41-45
17823114-3	2007	Sequence alignment with other K+ channels shows that hERG possesses glycine residues (Gly648 and Gly657) at each of these putative hinge sites.	Glycine	68-75	ETS transcription factor ERG	Homo sapiens	53-57
17823114-7	2007	Molecular dynamics simulations indicate the S6 helices of hERG are inherently flexible, even in the absence of the glycine residues.	Glycine	115-122	ETS transcription factor ERG	Homo sapiens	58-62
17823114-9	2007	Our findings indicate that the hERG inner helix glycine residues are required for the tight packing of the channel helices and that the flexibility afforded by glycine or proline residues is not universally required for activation gating.	Glycine	48-55	ETS transcription factor ERG	Homo sapiens	31-35
18073551-9	2007	The loss of inhibitory effect of xenon and isoflurane in mutant NR1(F639A)/NR2A receptors is explained by increased glycine affinity of the mutant receptors, and inhibition is restored at low glycine concentrations.	Glycine	116-123	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	64-67
18073551-9	2007	The loss of inhibitory effect of xenon and isoflurane in mutant NR1(F639A)/NR2A receptors is explained by increased glycine affinity of the mutant receptors, and inhibition is restored at low glycine concentrations.	Glycine	116-123	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	75-79
18073551-9	2007	The loss of inhibitory effect of xenon and isoflurane in mutant NR1(F639A)/NR2A receptors is explained by increased glycine affinity of the mutant receptors, and inhibition is restored at low glycine concentrations.	Glycine	192-199	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	64-67
18073551-9	2007	The loss of inhibitory effect of xenon and isoflurane in mutant NR1(F639A)/NR2A receptors is explained by increased glycine affinity of the mutant receptors, and inhibition is restored at low glycine concentrations.	Glycine	192-199	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	75-79
17944527-9	2007	The use of glutamic acid in the chelator sequences for (99m)Tc-labeling of Z(HER2:342) reduced the hepatobiliary excretion 3-fold with a single Gly-to-Glu substitution and 10-fold with three Gly-to-Glu substitutions.	Glycine	144-147	erb-b2 receptor tyrosine kinase 2	Homo sapiens	77-81
17944527-9	2007	The use of glutamic acid in the chelator sequences for (99m)Tc-labeling of Z(HER2:342) reduced the hepatobiliary excretion 3-fold with a single Gly-to-Glu substitution and 10-fold with three Gly-to-Glu substitutions.	Glycine	191-194	erb-b2 receptor tyrosine kinase 2	Homo sapiens	77-81
17970719-7	2007	Manipulations of endogenous glycine levels using sarcosine or ALX 5407 (inhibitors of the glycine re-uptake protein, GlyT1b), produced similar effects to glycine site agonists, including increased episode durations, and modulations in cycle period and burst amplitude.	Glycine	28-35	solute carrier family 6 member 9 S homeolog	Xenopus laevis	117-123
17970719-7	2007	Manipulations of endogenous glycine levels using sarcosine or ALX 5407 (inhibitors of the glycine re-uptake protein, GlyT1b), produced similar effects to glycine site agonists, including increased episode durations, and modulations in cycle period and burst amplitude.	Glycine	90-97	solute carrier family 6 member 9 S homeolog	Xenopus laevis	117-123
17970719-7	2007	Manipulations of endogenous glycine levels using sarcosine or ALX 5407 (inhibitors of the glycine re-uptake protein, GlyT1b), produced similar effects to glycine site agonists, including increased episode durations, and modulations in cycle period and burst amplitude.	Glycine	90-97	solute carrier family 6 member 9 S homeolog	Xenopus laevis	117-123
17720757-4	2007	An aspartate-2078-glycine (Gly) mutation in the plastidic ACCase enzyme has been identified as the only known mutation endowing clethodim resistance.	Glycine	27-30	acetyl-CoA carboxylase 2	Triticum aestivum	58-64
17944948-4	2007	Bip-Pro inhibited the [(14)C]Gly-Sar uptake via PEPT1 and PEPT2 with exceptional high affinity (K(i) = 24 microm and 3.4 microm, respectively) in a competitive manner.	Glycine	29-32	heat shock protein family A (Hsp70) member 5	Homo sapiens	0-3
17944948-4	2007	Bip-Pro inhibited the [(14)C]Gly-Sar uptake via PEPT1 and PEPT2 with exceptional high affinity (K(i) = 24 microm and 3.4 microm, respectively) in a competitive manner.	Glycine	29-32	solute carrier family 15 member 1	Homo sapiens	48-53
17944948-4	2007	Bip-Pro inhibited the [(14)C]Gly-Sar uptake via PEPT1 and PEPT2 with exceptional high affinity (K(i) = 24 microm and 3.4 microm, respectively) in a competitive manner.	Glycine	29-32	solute carrier family 15 member 2	Homo sapiens	58-63
17944948-8	2007	Uptake was strongly inhibited, not only by unlabeled Bip-Pro but also by known peptide transporter substrates such as dipeptides, cefadroxil, Ala-4-nitroanilide and delta-aminolevulinic acid, but not by glycine.	Glycine	203-210	heat shock protein family A (Hsp70) member 5	Homo sapiens	53-56
17944948-10	2007	Hence, the uptake of Bip-Pro by PEPT2 is a high-affinity, low-capacity process in comparison to the uptake of Gly-Sar.	Glycine	110-113	heat shock protein family A (Hsp70) member 5	Homo sapiens	21-24
17944948-10	2007	Hence, the uptake of Bip-Pro by PEPT2 is a high-affinity, low-capacity process in comparison to the uptake of Gly-Sar.	Glycine	110-113	solute carrier family 15 member 2	Homo sapiens	32-37
17919237-8	2007	TNF-alpha mRNA expression was also suppressed in the livers in the Glycine group.	Glycine	67-74	tumor necrosis factor	Rattus norvegicus	0-9
17919237-9	2007	Furthermore, the serum levels of TNF-alpha and CINC in the Glycine group were significantly lower than those in the Control group (P&lt;0.05).	Glycine	59-66	tumor necrosis factor	Rattus norvegicus	33-42
17940047-2	2007	Recently, to elucidate the oligomerization pathway, we studied Abeta monomer folding and identified a decapeptide segment of Abeta, (21)Ala-(22)Glu-(23)Asp-(24)Val-(25)Gly-(26)Ser-(27)Asn-(28)Lys-(29)Gly-(30)Ala, within which turn formation appears to nucleate monomer folding.	Glycine	168-171	amyloid beta precursor protein	Homo sapiens	125-130
17940047-2	2007	Recently, to elucidate the oligomerization pathway, we studied Abeta monomer folding and identified a decapeptide segment of Abeta, (21)Ala-(22)Glu-(23)Asp-(24)Val-(25)Gly-(26)Ser-(27)Asn-(28)Lys-(29)Gly-(30)Ala, within which turn formation appears to nucleate monomer folding.	Glycine	200-203	amyloid beta precursor protein	Homo sapiens	125-130
17982230-6	2007	Analysis of TAP1 gene polymorphism demonstrated decreased frequencies of Ile/Val genotype at codon 333, Asp/Gly genotype at codon 637, and haplotype A and B in allergic rhinitis patients when compared to controls (p&lt;0.05).	Glycine	108-111	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	12-16
17962466-10	2007	Unexpectedly, K18 bearing phakosin HIM resulted in normal IF assembly, despite the presence of an otherwise disease-causing R-C substitution, and two helix-disrupting glycines.	Glycine	167-175	beaded filament structural protein 2	Homo sapiens	26-34
17847018-5	2007	Finally, we propose that the structure of substance P can be partially inferred from its sequence due to the presence of a Pro-X-Pro motif on the N-terminus and a Gly-Leu sequence on the C-terminus.	Glycine	163-166	tachykinin precursor 1	Homo sapiens	42-53
17890402-6	2007	Time-of-flight secondary ion mass spectrometry showed that relative intensities of both sulfur-containing (cystine, methionine) and hydrophobic (glycine, leucine/isoleucine) amino acids varied with changing Fn surface coverage, indicating that the conformation of adsorbed Fn depended on surface coverage.	Glycine	145-152	fibronectin 1	Homo sapiens	207-209
17720757-6	2007	Several known ACCase mutations (isoleucine-1781-leucine [Leu], tryptophan-2027-cysteine [Cys], isoleucine-2041-asparagine, and aspartate-2078-Gly) and in particular, a new mutation of Cys to arginine at position 2088, were identified in plants surviving the Australian clethodim field rate (60 g ha(-1)).	Glycine	142-145	acetyl-CoA carboxylase 2	Triticum aestivum	14-20
17617428-5	2007	We have previously reported that NR3A contains a glycine binding site, with similar affinity as the glycine binding site of NR1 subunits.	Glycine	100-107	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	124-127
17686774-4	2007	Substitution of either Cys-592 or Cys-608 located in the extracellular loop to glycine resulted in a significant decrease in protein levels of ABCG2 when expressed in Flp-In-293 cells.	Glycine	79-86	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	143-148
17656358-2	2007	In this system, the C terminus of actin is fused to thymosin beta via a glycine-based linker.	Glycine	72-79	actin	Saccharomyces cerevisiae S288C	34-39
18035190-17	2007	In the GLY+RSG group, there were significant improvements in tPA (-17.8%; P &lt; 0.001), vWF (-11.3%; P = 0.019), and UACR (-17.2%; P = 0.028) over 24 weeks" treatment, whereas there were no significant changes in any of these factors in the GLY+PBO group.	Glycine	7-10	plasminogen activator, tissue type	Homo sapiens	61-64
17706944-4	2007	To that aim, transgenic mice expressing a mutant form of SOD1 [the gly(93) --> ala (G93A) substitution; G93A SOD1] were fed on either tomato-enriched food pellets or the Altromin diet in which milk serum and proteins substitute for soy and fish flours.	Glycine	67-70	superoxide dismutase 1, soluble	Mus musculus	57-61
18035190-17	2007	In the GLY+RSG group, there were significant improvements in tPA (-17.8%; P &lt; 0.001), vWF (-11.3%; P = 0.019), and UACR (-17.2%; P = 0.028) over 24 weeks" treatment, whereas there were no significant changes in any of these factors in the GLY+PBO group.	Glycine	7-10	von Willebrand factor	Homo sapiens	89-92
17537656-2	2007	The predicted prepro-NPY peptide contained a putative signal peptide of 28 amino acids and a mature NPY of 36 amino acids, followed by the proteolytic processing site Gly-Lys-Arg and 35 amino acids that comprise the C-terminal peptide of NPY.	Glycine	167-170	neuropeptide Y	Rattus norvegicus	21-24
17425670-6	2007	The N-terminal glycine, a myristoylation site in Arf3p, is necessary for its suppressor activity.	Glycine	15-22	Arf family GTPase ARF3	Saccharomyces cerevisiae S288C	49-54
17537719-9	2007	The ability of cytochrome c to catalyze the formation of oleoylglycine experimentally indicates the potential importance of cytochrome c as a novel mechanism for the generation of long chain fatty acyl glycine messengers in vivo.	Glycine	63-70	cytochrome c, somatic	Homo sapiens	15-27
17715062-5	2007	In this study, the ligand-binding core of GluRdelta2 (GluRdelta2-S1S2) was found to bind neutral amino acids such as D-serine and glycine, as demonstrated by isothermal titration calorimetry.	Glycine	130-137	glutamate receptor, ionotropic, delta 2	Mus musculus	42-52
17715062-5	2007	In this study, the ligand-binding core of GluRdelta2 (GluRdelta2-S1S2) was found to bind neutral amino acids such as D-serine and glycine, as demonstrated by isothermal titration calorimetry.	Glycine	130-137	glutamate receptor, ionotropic, delta 2	Mus musculus	54-69
17715062-7	2007	Functionally, D-serine and glycine were shown to inactivate spontaneous ion-channel conductance in GluRdelta2 containing the lurcher mutation (EC(50) values, 182 and 507 microM, respectively).	Glycine	27-34	glutamate receptor, ionotropic, delta 2	Mus musculus	99-109
17537719-2	2007	Here we report that cytochrome c catalyzes the formation of oleoylglycine from oleoyl-CoA and glycine, in the presence of hydrogen peroxide.	Glycine	66-73	cytochrome c, somatic	Homo sapiens	20-32
17671710-7	2007	This mutation was a G-to-T transversion, involving the substitution of the normal glycine (GGT) with cystein (TGT) and thought to be a somatic mutation.	Glycine	82-89	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	110-113
17709567-9	2007	Receptor specificity of the epididymal OT effects was verified using the selective OT receptor (OTR) agonist [Thr(4),Gly(7)]OT and vasopressin.	Glycine	117-120	oxytocin receptor	Bos taurus	96-99
17537719-9	2007	The ability of cytochrome c to catalyze the formation of oleoylglycine experimentally indicates the potential importance of cytochrome c as a novel mechanism for the generation of long chain fatty acyl glycine messengers in vivo.	Glycine	63-70	cytochrome c, somatic	Homo sapiens	124-136
17592510-6	2007	Adhesion assays revealed that baicalein stimulated endothelial cell adhesion to fibronectin and vitronectin, effects blocked by the synthetic peptide Arg-Gly-Asp (RGD).	Glycine	154-157	vitronectin	Rattus norvegicus	96-107
17459877-6	2007	In hippocampal cultures, brief (5 min), robust (100 microM NMDA, 10 microM glycine) activation of the NMDA receptor decreased biotinylated EAAC1 to approximately 50% of control levels.	Glycine	75-82	solute carrier family 1 member 1	Homo sapiens	139-144
17585854-0	2007	From tyrosine to glycine: synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor.	Glycine	17-24	purinergic receptor P2X 7	Homo sapiens	100-113
17585854-4	2007	Antagonistic activity of these glycine derivatives was tested on HEK293 cells transfected with the human P2X7 receptor.	Glycine	31-38	purinergic receptor P2X 7	Homo sapiens	105-118
17555723-7	2007	The results suggest the existence of the following K+ channel subtypes on glycinergic nerve endings that are involved in regulating "spontaneous" glycine release (mIPSCs): the Shaker-related K+ channels Kv1.1, Kv1.2, Kv1.3, Kv1.6 and Kv1.7 and the intracellular Ca2+ -sensitive K+ channels BKCa, IKCa and SKCa.	Glycine	74-81	potassium voltage-gated channel subfamily A member 6	Rattus norvegicus	224-229
17498917-4	2007	A c.115G&gt;A missense mutation in PPIB alters a glycine residue that has been conserved across vertebrates.	Glycine	49-56	peptidylprolyl isomerase B	Equus caballus	35-39
17554807-8	2007	These results indicate that Gly-Pro-Hyp can be partially hydrolyzed by the brush-border membrane-bound aminopeptidase N to remove Gly, and that the resulting Pro-Hyp is, in part, transported into the small intestinal epithelial cells via the H+-coupled PEPT1.	Glycine	28-31	solute carrier family 15 member 1	Homo sapiens	253-258
17503466-3	2007	The predicated NBS of murine VDAC1 (mVDAC1) was mutated by replacing two glycine residues with alanines or a conserved lysine residue with a serine.	Glycine	73-80	voltage-dependent anion channel 1	Mus musculus	29-34
17503466-3	2007	The predicated NBS of murine VDAC1 (mVDAC1) was mutated by replacing two glycine residues with alanines or a conserved lysine residue with a serine.	Glycine	73-80	voltage-dependent anion channel 1	Mus musculus	36-42
17502428-0	2007	Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.	Glycine	36-43	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	112-115
17502428-7	2007	The NMDA receptor glycine site agonist, d-serine, partially activated NR1/NR3A/NR3B receptors, whereas the antagonist, 5,7-dichloro-kynurenic acid, inhibited receptor currents.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	70-73
17678539-5	2007	However, due to the distinct characteristics of A12L proteolysis such as the localization of both the A12L full-length protein and its cleavage product in mature virions and two putative cleavage sites (Ala-Gly-Lys) located at internal and C-terminal region of A12L ORF, it was of interest to examine the A12L proteolysis for better understanding of regulation and function of VV proteolysis.	Glycine	207-210	core protein	Vaccinia virus	48-52
17481605-3	2007	The fMLP-OMe analogues synthesized, with the general formula for-Met-Leu-Phe-Xaa-Lys(OMe)-Phe-Leu-Met-for (Xaa=Gly, beta-Ala, gamma-aminobutyric acid, 5-aminovaleric acid, and 6-aminocaproic acid), were constituted by two fMLP units linked by a Lys residue, with an amino acid spacer between them.	Glycine	111-114	formyl peptide receptor 1	Homo sapiens	4-8
17499207-12	2007	The Asp380 amino acid residue appears to be important in myocilin function based on the finding that substitution of this amino acid with four different amino acids (His, Ala, Asn, or Gly) all result in a similar presentation of POAG that is intermediate between the more severe clinical presentations observed in individuals with the Pro370Leu or Lys423Glu variant and the milder findings in patients with the Gln368Stop mutation.	Glycine	184-187	myocilin	Homo sapiens	57-65
17546040-4	2007	Biochemical analyses showed that Dyn2 binds to a linear motif (termed DID(Nup159)) inserted between the Phe-Gly repeat and coiled-coil domain of Nup159.	Glycine	108-111	FG-nucleoporin NUP159	Saccharomyces cerevisiae S288C	74-80
17546040-6	2007	These findings imply that the rigid 20 nm long Dyn2-DID(Nup159) filament projects the Nup159 Phe-Gly repeats from the Nup82 module.	Glycine	97-100	FG-nucleoporin NUP159	Saccharomyces cerevisiae S288C	56-62
17546040-6	2007	These findings imply that the rigid 20 nm long Dyn2-DID(Nup159) filament projects the Nup159 Phe-Gly repeats from the Nup82 module.	Glycine	97-100	linker nucleoporin NUP82	Saccharomyces cerevisiae S288C	118-123
17612631-0	2007	Probing the role of the conserved beta-II turn Pro-76/Gly-77 of mitochondrial cytochrome c.	Glycine	54-57	cytochrome c, somatic	Homo sapiens	78-90
17511476-11	2007	Substitution of RGS7 Glu-73 and Asp-74 for the corresponding Ser and Gly residues (ED/SG mutation) of RGS9 diminished the DEP-Gbeta5 interaction.	Glycine	69-72	G protein subunit beta 5	Homo sapiens	126-132
17517106-11	2007	Immunization with P-Gly induced the production of IFN-gamma [T-helper type 1 (Th1) response] and lowered the production of IL-4 (Th2 response), and a skewed balance towards the Th1 cytokine demonstrated that P-Gly has a modulating ability on Th1/Th2 balance to down-regulate Th2 response.	Glycine	20-23	interferon gamma	Mus musculus	50-59
17473569-0	2007	Effect of glycine on the calcium signal of thrombin-stimulated platelets.	Glycine	10-17	coagulation factor II, thrombin	Homo sapiens	43-51
17473569-6	2007	When NaCl was replaced by sodium glycine, the [Ca]i increase produced by thrombin was enhanced, because the calcium entry increased without changes in the mobilization of stored calcium.	Glycine	26-40	coagulation factor II, thrombin	Homo sapiens	73-81
17473569-7	2007	The addition of 50 mmol/l glycine base to the HEPES-buffered media increases the thrombin-induced entry of calcium or manganese.	Glycine	26-33	coagulation factor II, thrombin	Homo sapiens	81-89
17456564-0	2007	A case for "StopGo": reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go).	Glycine	144-151	gametogenetin	Homo sapiens	75-78
20641448-0	2004	[(99m)Tc(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) [(99m)Tc-(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) ((99m)Tc(N)(PNP3)-CCK-8) is a radiolabeled peptide developed for single-photon emission computed tomography (SPECT) imaging of tumors that express the gastrin/cholecystokinin-2 (CCK-2) receptor (1).	Glycine	19-22	cholecystokinin B receptor	Rattus norvegicus	259-274
17357163-2	2007	Nine alpha-MSH peptide analogues were constructed by exchanging the Trp9 residue in the alpha-MSH core with the natural or artificial amino acids Arg, Asp, Cys, Gly, Leu, Nal, d-Nal, Pro, or d-Trp.	Glycine	161-164	proopiomelanocortin	Homo sapiens	5-14
17469798-3	2007	In ALAS, replacing the equivalent histidine, H282, with alanine reduces the catalytic efficiency for glycine 450-fold and decreases the slow phase rate for glycine binding by 85%.	Glycine	101-108	5'-aminolevulinate synthase 1	Homo sapiens	3-7
17469798-3	2007	In ALAS, replacing the equivalent histidine, H282, with alanine reduces the catalytic efficiency for glycine 450-fold and decreases the slow phase rate for glycine binding by 85%.	Glycine	156-163	5'-aminolevulinate synthase 1	Homo sapiens	3-7
17469798-6	2007	The 300-500 nm circular dichroism spectra of ALAS and H282A diverged in the presence of either glycine or aminolevulinate, indicating that the reorientation of the PLP cofactor upon external aldimine formation is impeded in H282A.	Glycine	95-102	5'-aminolevulinate synthase 1	Homo sapiens	45-49
17386920-4	2007	Under the actions of ACE and aminoacylase, 3HB-GGG is cleaved into amino acids (Gly and Gly-Gly) and 3-hydroxybutyric acid (3HB).	Glycine	80-83	angiotensin I converting enzyme	Homo sapiens	21-24
17512307-5	2007	Among whites, the ADRB1 Arg389--&gt;Gly variant associated with insulin concentrations and HOMA(IR): mean +/- SD values for insulin and HOMA(IR) in Arg389 homozygotes and carriers of the Gly were 10 +/- 7.0 and 12 +/- 9.4 micro IU/mL (P = .02) and 2.1 +/- 1.7 and 2.6 +/- 2.2 (P = .057), respectively.	Glycine	36-39	insulin	Homo sapiens	64-71
17512307-5	2007	Among whites, the ADRB1 Arg389--&gt;Gly variant associated with insulin concentrations and HOMA(IR): mean +/- SD values for insulin and HOMA(IR) in Arg389 homozygotes and carriers of the Gly were 10 +/- 7.0 and 12 +/- 9.4 micro IU/mL (P = .02) and 2.1 +/- 1.7 and 2.6 +/- 2.2 (P = .057), respectively.	Glycine	36-39	insulin	Homo sapiens	124-131
17512307-5	2007	Among whites, the ADRB1 Arg389--&gt;Gly variant associated with insulin concentrations and HOMA(IR): mean +/- SD values for insulin and HOMA(IR) in Arg389 homozygotes and carriers of the Gly were 10 +/- 7.0 and 12 +/- 9.4 micro IU/mL (P = .02) and 2.1 +/- 1.7 and 2.6 +/- 2.2 (P = .057), respectively.	Glycine	187-190	insulin	Homo sapiens	64-71
17512307-5	2007	Among whites, the ADRB1 Arg389--&gt;Gly variant associated with insulin concentrations and HOMA(IR): mean +/- SD values for insulin and HOMA(IR) in Arg389 homozygotes and carriers of the Gly were 10 +/- 7.0 and 12 +/- 9.4 micro IU/mL (P = .02) and 2.1 +/- 1.7 and 2.6 +/- 2.2 (P = .057), respectively.	Glycine	187-190	insulin	Homo sapiens	124-131
17504107-3	2007	An actively pursued strategy to potentiate NMDA receptor function is to increase synaptic levels of the neurotransmitter glycine by blocking the glycine transporter type 1 (GlyT1).	Glycine	121-128	solute carrier family 6 member 9	Homo sapiens	145-171
17383967-2	2007	There are two Na(+)/Cl(-)-dependent glycine transporters, GLYT1 and GLYT2, which control extracellular glycine concentrations and these transporters show differences in substrate selectivity and blocker sensitivity.	Glycine	36-43	solute carrier family 6 member 9	Homo sapiens	58-63
17383967-5	2007	In this report, we demonstrate that the LeuT(Aa) structure represents a good working model of the Na(+)/Cl(-)-dependent neurotransmitters and that differences in substrate selectivity can be attributed to a single difference of a glycine residue in transmembrane domain 6 of GLYT1 for a serine residue at the corresponding position of GLYT2.	Glycine	230-237	solute carrier family 6 member 9	Homo sapiens	275-280
17504107-3	2007	An actively pursued strategy to potentiate NMDA receptor function is to increase synaptic levels of the neurotransmitter glycine by blocking the glycine transporter type 1 (GlyT1).	Glycine	121-128	solute carrier family 6 member 9	Homo sapiens	173-178
17336327-12	2007	In addition, as indicated by 1H, 15N and 13CO chemical-shifts, the glycine substitutions diminished the enzyme"s response to ligand, and induced structural perturbations in apo and 2-PGA-bound forms of TIM that are atypical of WT.	Glycine	67-74	triosephosphate isomerase 1	Homo sapiens	202-205
17301132-7	2007	Coincidentally, a cluster of proline, arginine, and glycine precedes the Gag-Pol junction of MuLV.	Glycine	52-59	Gag-Pol	Human immunodeficiency virus 1	73-80
17308032-0	2007	Insulin increases the potency of glycine at ionotropic glycine receptors.	Glycine	33-40	insulin	Homo sapiens	0-7
17308032-3	2007	Whole-cell patch-clamp recordings showed that insulin reversibly enhanced current evoked by exogenous glycine and increased the amplitude of spontaneous glycinergic miniature inhibitory postsynaptic currents recorded in cultured spinal neurons.	Glycine	102-109	insulin	Homo sapiens	46-53
17308032-4	2007	Insulin (1 microM) also shifted the glycine concentration-response plot to the left and reduced the glycine EC(50) value from 52 to 31 microM.	Glycine	36-43	insulin	Homo sapiens	0-7
17308032-8	2007	Together, these results show that insulin has a novel regulatory action on the potency of glycine for ionotropic glycine receptors.	Glycine	90-97	insulin	Homo sapiens	34-41
17403555-9	2007	Stimulation of NR1/NR2A receptors with NMDA/glycine revealed an increase in intracellular calcium in cells pre-exposed to Abeta(1-40).	Glycine	44-51	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	15-18
17403555-9	2007	Stimulation of NR1/NR2A receptors with NMDA/glycine revealed an increase in intracellular calcium in cells pre-exposed to Abeta(1-40).	Glycine	44-51	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	19-23
17403555-9	2007	Stimulation of NR1/NR2A receptors with NMDA/glycine revealed an increase in intracellular calcium in cells pre-exposed to Abeta(1-40).	Glycine	44-51	amyloid beta precursor protein	Homo sapiens	122-127
17339324-7	2007	A mutational analysis of the DEDG sequence of CLEC-2 revealed that the glycine residue directly upstream of the YXXL tyrosine is important for CLEC-2 signaling.	Glycine	71-78	C-type lectin domain family 1 member B	Homo sapiens	46-52
17339324-7	2007	A mutational analysis of the DEDG sequence of CLEC-2 revealed that the glycine residue directly upstream of the YXXL tyrosine is important for CLEC-2 signaling.	Glycine	71-78	C-type lectin domain family 1 member B	Homo sapiens	143-149
17276019-1	2007	A single point mutation (G to T) in the low-density lipoprotein receptor related protein 5 (LRP5) gene results in a glycine to valine amino acid change (G171V) and is responsible for an autosomal dominant high bone mass trait (HBM) in two independent kindreds.	Glycine	116-123	LDL receptor related protein 5	Homo sapiens	40-90
17398095-3	2007	ARNO and its three relatives, cytohesin-1, Grp1/cytohesin-3, and cytohesin-4, are expressed as two splice variants, with either two or three glycines in a loop in the phosphoinositide-binding pocket of the PH domain [5, 6].	Glycine	141-149	cytohesin 2	Homo sapiens	0-4
17398095-3	2007	ARNO and its three relatives, cytohesin-1, Grp1/cytohesin-3, and cytohesin-4, are expressed as two splice variants, with either two or three glycines in a loop in the phosphoinositide-binding pocket of the PH domain [5, 6].	Glycine	141-149	cytohesin 1	Homo sapiens	30-41
17276019-1	2007	A single point mutation (G to T) in the low-density lipoprotein receptor related protein 5 (LRP5) gene results in a glycine to valine amino acid change (G171V) and is responsible for an autosomal dominant high bone mass trait (HBM) in two independent kindreds.	Glycine	116-123	LDL receptor related protein 5	Homo sapiens	92-96
17276019-8	2007	Here we show that substitutions of glycine at 171 to K, F, I and Q also resulted in HBM-like activity in the presence of Wnt1 and Dkk1.	Glycine	35-42	Wnt family member 1	Homo sapiens	121-125
17347650-5	2007	Consistently, a downregulation of GlyR clusters was detected in hippocampal neurons derived from Pin1 knockout mice, which was paralleled by a reduction in the amplitude of glycine-evoked currents.	Glycine	173-180	peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1	Mus musculus	97-101
17407174-7	2007	The affinity of the tripeptides to hPEPT1 was determined by measuring the inhibition of [(14)C]Gly-Sar in mature Caco-2 cell monolayers which resulted in K(i) values ranging from 0.22 to 25 mM or above.	Glycine	95-98	solute carrier family 15 member 1	Homo sapiens	35-41
17391066-5	2007	The enzyme acts upon bradykinin mainly as a carboxydipeptidase, preferentially cleaving Pro-Phe over the Gly-Phe bond in a 9:1 ratio, whereas Abz-RPPGFSPFRQ-EDDnp was hydrolyzed at the same bonds but at an inverted proportion of 1:9.	Glycine	105-108	kininogen 1	Homo sapiens	21-31
17407174-8	2007	Translocation through the intestinal membrane, mediated by hPEPT1, was measured by recording the membrane potential relative to that induced by the known substrate Gly-Sar.	Glycine	164-167	solute carrier family 15 member 1	Homo sapiens	59-65
17188389-5	2007	Glycine protection required the activation of a signal pathway involving Src, Pyk2 and p38 MAP kinases.	Glycine	0-7	protein tyrosine kinase 2 beta	Rattus norvegicus	78-82
17188389-7	2007	The prevention of cell swelling by hepatocyte incubation in a hypertonic medium as well as the degradation of extracellular ATP with apyrase or the block P2 purinergic receptors with suramin reverted glycine-induced cytoprotection and inhibited Src, Pyk2 and p38 MAPK activation.	Glycine	200-207	protein tyrosine kinase 2 beta	Rattus norvegicus	250-254
17188389-10	2007	CONCLUSIONS: Glycine-induced ATP release in response to a moderate hepatocyte swelling led to the autocrine stimulation of P2 receptors and to the activation of Src, Pyk2 and p38 MAPK that increased hepatocyte resistance to hypoxia by preventing Na+ influx through NHE.	Glycine	13-20	protein tyrosine kinase 2 beta	Rattus norvegicus	166-170
17332749-5	2007	In a neuronal cell system, mutations of glycine residues G29 and G33 of the GxxxG motif gradually attenuate the TMS dimerization strength, specifically reduce the formation of Abeta42, leave the level of Abeta40 unaffected, but increase Abeta38 and shorter Abeta species.	Glycine	40-47	amyloid beta precursor protein	Homo sapiens	176-181
17427808-6	2007	Replacement of Gly-2 and Cys-3 (sites of posttranslational attachment of myristic and palmatic acids, respectively) with alanine affected AC4 membrane binding and pathogenesis.	Glycine	15-18	adenylate cyclase 4	Homo sapiens	138-141
17185393-8	2007	In addition, mutation of the vicinal glycine residues between the ligand-binding domain and F domains specifically reduced the 4-OHT-dependent interactions of the hERalpha ligand-binding domain and F domains with monobodies.	Glycine	37-44	Era like 12S mitochondrial rRNA chaperone 1	Homo sapiens	163-171
17286388-1	2007	Glu376, the base involved in substrate alphaH+ abstraction at the active center of medium-chain acyl-CoA dehydrogenase (MCAD), has been mutated to Gln and Gly.	Glycine	155-158	acyl-CoA dehydrogenase medium chain	Homo sapiens	83-118
17339498-2	2007	We have identified a common, nonsynonymous, single nucleotide polymorphism (SNP) in the coding region of CD89 (844A--&gt;G) (rs16986050), which changes codon 248 from AGC (Ser(248)) to GGC (Gly(248)) in the cytoplasmic domain of the receptor.	Glycine	190-193	Fc alpha receptor	Homo sapiens	105-109
17339498-4	2007	In the absence of FcR gamma-chain association in P388D1 cells, the Ser(248)-FcalphaRI allele does not mediate cytokine production, but the Gly(248)-FcalphaRI allele retains the capacity to mediate a robust production of proinflammatory cytokine.	Glycine	139-142	Fc alpha receptor	Homo sapiens	148-157
17339498-6	2007	These findings and the enrichment of the proinflammatory Gly(248)-FcalphaRI allele in systemic lupus erythematosus populations in two ethnic groups compared with their respective non-systemic lupus erythematosus controls suggest that FcalphaRI (CD89) alpha-chain alleles may affect receptor-mediated signaling and play an important role in the modulation of immune responses in inflammatory diseases.	Glycine	57-60	Fc alpha receptor	Homo sapiens	66-75
17339498-6	2007	These findings and the enrichment of the proinflammatory Gly(248)-FcalphaRI allele in systemic lupus erythematosus populations in two ethnic groups compared with their respective non-systemic lupus erythematosus controls suggest that FcalphaRI (CD89) alpha-chain alleles may affect receptor-mediated signaling and play an important role in the modulation of immune responses in inflammatory diseases.	Glycine	57-60	Fc alpha receptor	Homo sapiens	234-243
17339498-6	2007	These findings and the enrichment of the proinflammatory Gly(248)-FcalphaRI allele in systemic lupus erythematosus populations in two ethnic groups compared with their respective non-systemic lupus erythematosus controls suggest that FcalphaRI (CD89) alpha-chain alleles may affect receptor-mediated signaling and play an important role in the modulation of immune responses in inflammatory diseases.	Glycine	57-60	Fc alpha receptor	Homo sapiens	245-249
17286388-1	2007	Glu376, the base involved in substrate alphaH+ abstraction at the active center of medium-chain acyl-CoA dehydrogenase (MCAD), has been mutated to Gln and Gly.	Glycine	155-158	acyl-CoA dehydrogenase medium chain	Homo sapiens	120-124
17266049-1	2007	High affinity peptide ligands for the bradykinin (BK) B(2) subtype receptor have been shown to adopt a beta-turn conformation of the C-terminal tetrapeptide (H-Arg(1)-Pro(2)-Pro(3)-Gly(4)-Phe(5)-Ser(6)-Pro(7)-Phe(8)-Arg(9)-OH).	Glycine	181-184	kininogen 1	Homo sapiens	38-48
17214961-1	2007	Calcium-permeable N-methyl-d-aspartate (NMDA) receptors are tetrameric cation channels composed of glycine-binding NR1 and glutamate-binding NR2 subunits, which require binding of both glutamate and glycine for efficient channel gating.	Glycine	99-106	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	115-118
17446497-4	2007	Our chimeric and site-directed mutagenesis revealed that Phe-213, Val-227, Tyr-228, Gly-833, and Asn-839 in NCX1 are molecular determinants for interaction with SN-6.	Glycine	84-87	solute carrier family 8 member A1	Homo sapiens	108-112
17214961-3	2007	Here, we show that antagonists of and substitutions within the glycine-binding site of NR1 potentiate NR1/NR3 receptor function up to 25-fold, but inhibition or mutation of the NR3 glycine binding site reduces or abolishes receptor activation.	Glycine	63-70	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	87-90
17214961-3	2007	Here, we show that antagonists of and substitutions within the glycine-binding site of NR1 potentiate NR1/NR3 receptor function up to 25-fold, but inhibition or mutation of the NR3 glycine binding site reduces or abolishes receptor activation.	Glycine	63-70	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	102-105
17214961-3	2007	Here, we show that antagonists of and substitutions within the glycine-binding site of NR1 potentiate NR1/NR3 receptor function up to 25-fold, but inhibition or mutation of the NR3 glycine binding site reduces or abolishes receptor activation.	Glycine	181-188	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	87-90
17214961-4	2007	Thus, glycine bound to the NR1 subunit causes auto-inhibition of NR1/NR3 receptors whereas glycine binding to the NR3 subunits is required for opening of the ion channel.	Glycine	6-13	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	27-30
17214961-4	2007	Thus, glycine bound to the NR1 subunit causes auto-inhibition of NR1/NR3 receptors whereas glycine binding to the NR3 subunits is required for opening of the ion channel.	Glycine	6-13	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	65-68
17214961-5	2007	Our results establish differential roles of the high-affinity NR3 and low-affinity NR1 glycine-binding sites in excitatory glycine receptor function.	Glycine	87-94	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	83-86
17164427-3	2007	We evaluated fMLP-stimulated human neutrophil motility on peptides Arg-Gly-Asp-Ser (RGDS) and TMKIIPFNRTLIGG (P2), alone and in combination.	Glycine	71-74	formyl peptide receptor 1	Homo sapiens	13-17
17158446-7	2007	Site-directed mutagenesis studies of the active site histidine triad revealed that Hint labeling could be abolished by substitution of either His-101 of E. coli hinT or His-112 of human Hint1 by either alanine or glycine.	Glycine	213-220	histidine triad nucleotide binding protein 1	Homo sapiens	83-87
17158446-7	2007	Site-directed mutagenesis studies of the active site histidine triad revealed that Hint labeling could be abolished by substitution of either His-101 of E. coli hinT or His-112 of human Hint1 by either alanine or glycine.	Glycine	213-220	histidine triad nucleotide binding protein 1	Homo sapiens	186-191
17141888-5	2007	The results of our studies indicate that the modulation of gammaGT activity can be used to change cellular redox status, and can affect Cys- and Cys-Gly-dependent S-thiolation and caspase-3 activity.	Glycine	149-152	caspase 3	Homo sapiens	180-189
17320117-4	2007	The NMDA NR1 glycine site agonist d-serine and partial agonist HA-966 (3-amino-1-hydroxypyrrolid-2-one), similarly to glycine displaced [(3)H]-glycine monophasically, suggesting a single common binding site.	Glycine	13-20	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	9-12
16926174-11	2007	These results are consistent with the hypothesis that nitrosation of glycine (or glycine derivatives) may contribute to characteristic human p53 mutation profiles.	Glycine	69-76	tumor protein p53	Homo sapiens	141-144
17285142-3	2007	Accumulated experimental and bioinformatic evidence has suggested an alternative explanation based on amino acid constraint on the second codon, i.e., amino acid Ala or Gly are needed as the second amino acid in the nascent peptide for the cleavage of the initiator Met, and the consequent overuse of Ala and Gly codons (GCN and GGN) leads to the +4G consensus.	Glycine	169-172	gametogenetin	Homo sapiens	329-332
16926174-11	2007	These results are consistent with the hypothesis that nitrosation of glycine (or glycine derivatives) may contribute to characteristic human p53 mutation profiles.	Glycine	81-88	tumor protein p53	Homo sapiens	141-144
17285142-6	2007	Among the five G-starting codons, only alanine codons (GCN), and glycine codons (GGN) to a much smaller extent, are overrepresented at the second codon, whereas the other three codons are not overrepresented.	Glycine	65-72	gametogenetin	Homo sapiens	81-84
17142003-8	2007	One of the 50 patients had an EGFR mutation in codon 719, resulting in an amino acid substitution from glycine to aspartic acid.	Glycine	103-110	epidermal growth factor receptor	Homo sapiens	30-34
17007829-1	2007	BACKGROUND: A beta-hemoglobin variant (beta 126 (H4) Val--&gt;Gly) was reported from Thailand and Naples (Southern Italy) as Hb Dhonburi (1) and Hb Neapolis (2), respectively.	Glycine	62-65	amyloid beta precursor protein	Homo sapiens	12-18
17110428-3	2007	Here, we demonstrate that addition of OPN before IL-1beta in freshly isolated rat islets improved their glucose stimulated insulin secretion dose-dependently and inhibited IL-1beta-induced NO production in an arginine-glycine-aspartate-dependent manner.	Glycine	218-225	interleukin 1 beta	Rattus norvegicus	172-180
16832345-5	2007	This base substitution forms a valine-glutamic acid-glycine activation domain first identified in oncogenic ERBB2/HER2/Neu.	Glycine	52-59	erb-b2 receptor tyrosine kinase 2	Homo sapiens	108-113
16828498-3	2007	EBNA-1 can subdue immune recognition by virtue of a long glycine and alanine-rich repeat, which interferes with the proteasomal degradation of EBNA-1 and in this way averts the presentation of antigenic peptides derived from it.	Glycine	57-64	EBNA-1	Human gammaherpesvirus 4	0-6
17019612-5	2007	The glycine at position 2385 is a candidate site for N-myristoylation, and the Gly2385Arg variant replaces the hydrophobic glycine with the hydrophilic arginine, and increases the net positive charge of the LRRK2 WD40 domain.	Glycine	4-11	leucine rich repeat kinase 2	Homo sapiens	207-212
17019612-5	2007	The glycine at position 2385 is a candidate site for N-myristoylation, and the Gly2385Arg variant replaces the hydrophobic glycine with the hydrophilic arginine, and increases the net positive charge of the LRRK2 WD40 domain.	Glycine	123-130	leucine rich repeat kinase 2	Homo sapiens	207-212
16828498-3	2007	EBNA-1 can subdue immune recognition by virtue of a long glycine and alanine-rich repeat, which interferes with the proteasomal degradation of EBNA-1 and in this way averts the presentation of antigenic peptides derived from it.	Glycine	57-64	EBNA-1	Human gammaherpesvirus 4	143-149
16832345-5	2007	This base substitution forms a valine-glutamic acid-glycine activation domain first identified in oncogenic ERBB2/HER2/Neu.	Glycine	52-59	erb-b2 receptor tyrosine kinase 2	Homo sapiens	114-118
16832345-5	2007	This base substitution forms a valine-glutamic acid-glycine activation domain first identified in oncogenic ERBB2/HER2/Neu.	Glycine	52-59	erb-b2 receptor tyrosine kinase 2	Homo sapiens	119-122
17725041-8	2007	Altogether these data allow us to suggest the existence of a CB1R independent action of cannabinoids directly on glycine-activated currents, representing a novel antinociceptive mechanism of this compounds.	Glycine	113-120	cannabinoid receptor 1	Homo sapiens	61-65
17726307-8	2007	In addition, 10 polymorphisms, including 1 non-glycine missense variant and 9 neutral polymorphisms, were detected in COL4A3/COL4A4.	Glycine	47-54	collagen type IV alpha 4 chain	Homo sapiens	125-131
17224050-7	2007	Site directed mutation also reveals that amino acid residues Gly 70 and Val 72 are important in the VP2-vimentin association.	Glycine	61-64	VP2	Bluetongue virus	100-103
17721643-6	2007	The coding region of ECM1 was amplified and sequenced and both affected siblings were shown to have a novel homozygous single nucleotide substitution, c.658T&gt;G, in exon 6, which converts cysteine to glycine, designated p.C220G.	Glycine	202-209	extracellular matrix protein 1	Homo sapiens	21-25
17222361-4	2007	RESULTS: Among the 46 specimens of NPC, 2 (4.3%) had point mutation in PIK3CA exon 9 [T1563G (521Asn--&gt;Lys) and A1646G (549Asp--&gt;Gly)], 18 had multiple mutations in PIK3CA exon 9 (A1634C-G1658C-del 1659T), which might be the homologous sequence of Cat Eye Syndrome region on 22q11.2; none had mutation in PIK3CA exon 20.	Glycine	135-138	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	71-77
16885150-15	2007	Plasma membrane TLR4 release through glycine-suppressible pores, possibly coupled with a translation block, appears to be involved.	Glycine	37-44	toll-like receptor 4	Mus musculus	16-20
16978906-8	2007	Arginine-glycine-aspartic acid-serine stimulated Phosphoinositol-3 kinase activity, and Transforming growth factor-beta1 promoter activation was abrogated by the use of Phosphoinositol-3 kinase specific inhibitors.	Glycine	9-16	transforming growth factor beta 1	Homo sapiens	88-120
16978906-0	2007	Role of activator protein-1 on the effect of arginine-glycine-aspartic acid containing peptides on transforming growth factor-beta1 promoter activity.	Glycine	54-61	transforming growth factor beta 1	Homo sapiens	99-131
16978906-9	2007	In summary, we propose that arginine-glycine-aspartic acid-serine activates Integrin linked kinase via the Phosphoinositol-3 kinase pathway and this leads to activation of c-jun and c-fos and increased Activator protein-1 binding and Transforming growth factor-beta1 promoter activity.	Glycine	37-44	integrin linked kinase	Homo sapiens	76-98
16978906-9	2007	In summary, we propose that arginine-glycine-aspartic acid-serine activates Integrin linked kinase via the Phosphoinositol-3 kinase pathway and this leads to activation of c-jun and c-fos and increased Activator protein-1 binding and Transforming growth factor-beta1 promoter activity.	Glycine	37-44	transforming growth factor beta 1	Homo sapiens	234-266
17047094-0	2007	Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	67-70
17047094-1	2007	N-Methyl-D-aspartate receptors (NMDARs) composed of NR1 and NR3 subunits differ from other NMDAR subtypes in that they require glycine alone for activation.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	52-55
17047094-6	2007	Ligand studies of NR1/NR3 receptors also suggest differential agonist selectivity between NR3 and NR1, as some high-affinity NR1 agonists only minimally activate NR1/NR3 receptors, whereas other NR1 agonists are as potent as glycine.	Glycine	225-232	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	18-21
17047094-6	2007	Ligand studies of NR1/NR3 receptors also suggest differential agonist selectivity between NR3 and NR1, as some high-affinity NR1 agonists only minimally activate NR1/NR3 receptors, whereas other NR1 agonists are as potent as glycine.	Glycine	225-232	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	98-101
17047094-6	2007	Ligand studies of NR1/NR3 receptors also suggest differential agonist selectivity between NR3 and NR1, as some high-affinity NR1 agonists only minimally activate NR1/NR3 receptors, whereas other NR1 agonists are as potent as glycine.	Glycine	225-232	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	98-101
17047094-6	2007	Ligand studies of NR1/NR3 receptors also suggest differential agonist selectivity between NR3 and NR1, as some high-affinity NR1 agonists only minimally activate NR1/NR3 receptors, whereas other NR1 agonists are as potent as glycine.	Glycine	225-232	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	98-101
17047094-6	2007	Ligand studies of NR1/NR3 receptors also suggest differential agonist selectivity between NR3 and NR1, as some high-affinity NR1 agonists only minimally activate NR1/NR3 receptors, whereas other NR1 agonists are as potent as glycine.	Glycine	225-232	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	98-101
17154529-1	2006	Glycine N-methyltransferase (GNMT) is an S-adenosyl-l-methionine dependent enzyme that catalyzes glycine transformation to sarcosine.	Glycine	97-104	glycine N-methyltransferase	Homo sapiens	0-27
17050777-7	2007	AQ-tetraamines could permeate the channel at very negative membrane potentials when the narrowest constriction of the channel was expanded by replacing the Asn residue at Asn616 of NR1 and NR2B with Gly, whereas Ant-tetraamines did not easily pass through the channel, apparently because of differences in the relative position of the head groups on AQ- and Ant-polyamines.	Glycine	199-202	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	181-184
17009102-5	2007	RESULTS: The reverse-charge mutants R282D-hPepT1 and D341R-hPepT1 showed significantly reduced gly-sar uptake, but the double mutant (R282D/D341R-hPepT1) has functionality comparable to that of wild-type hPepT1.	Glycine	95-98	solute carrier family 15 member 1	Homo sapiens	42-48
17009102-5	2007	RESULTS: The reverse-charge mutants R282D-hPepT1 and D341R-hPepT1 showed significantly reduced gly-sar uptake, but the double mutant (R282D/D341R-hPepT1) has functionality comparable to that of wild-type hPepT1.	Glycine	95-98	solute carrier family 15 member 1	Homo sapiens	59-65
17009102-5	2007	RESULTS: The reverse-charge mutants R282D-hPepT1 and D341R-hPepT1 showed significantly reduced gly-sar uptake, but the double mutant (R282D/D341R-hPepT1) has functionality comparable to that of wild-type hPepT1.	Glycine	95-98	solute carrier family 15 member 1	Homo sapiens	59-65
17009102-5	2007	RESULTS: The reverse-charge mutants R282D-hPepT1 and D341R-hPepT1 showed significantly reduced gly-sar uptake, but the double mutant (R282D/D341R-hPepT1) has functionality comparable to that of wild-type hPepT1.	Glycine	95-98	solute carrier family 15 member 1	Homo sapiens	59-65
17009102-6	2007	Gly-sar uptake by R282C-hPepT1 is reduced, but pre-incubation with 1 mM MTSET, a positively charged cysteine-modifying reagent, restored function to wild-type levels.	Glycine	0-3	solute carrier family 15 member 1	Homo sapiens	24-30
17009102-7	2007	Similarly, pre-incubation of D341C-hPepT1 with 10 mM MTSES, a negatively charged cysteine-modifying reagent, increased gly-sar uptake compared to unmodified D341C-hPepT1.	Glycine	119-122	solute carrier family 15 member 1	Homo sapiens	35-41
17009102-8	2007	In contrast, MTSET modification of D341C-hPepT1 (giving a positive charge at position 341) resulted in significant reduction in gly-sar uptake, compared to D341C-hPepT1.	Glycine	128-131	solute carrier family 15 member 1	Homo sapiens	41-47
17432611-12	2007	In HEK-293 cells recorded under conditions of low intracellular Ca concentration (BAPTA 20 mM in the recording pipette), EC50 for glycine in control cells and expressing GlyRhl + CaBP-S were, correspondently, 68+/-49 microM (n = 29) and 409 +/-421 microM (n = 60).	Glycine	130-137	S100 calcium binding protein G	Homo sapiens	179-183
17154529-1	2006	Glycine N-methyltransferase (GNMT) is an S-adenosyl-l-methionine dependent enzyme that catalyzes glycine transformation to sarcosine.	Glycine	97-104	glycine N-methyltransferase	Homo sapiens	29-33
17154529-3	2006	The process takes place through an SN2 mechanism in both media with a transition state in which the transferring methyl group is placed in between the donor (SAM) and the acceptor (the amine group of glycine).	Glycine	200-207	solute carrier family 38 member 5	Homo sapiens	35-38
16899062-3	2006	Here we report that N-arachidonyl-glycine is a reversible and non-competitive inhibitor of glycine transport by GLYT2a, but has little effect on glycine transport by GLYT1b or gamma-amino butyric acid transport by GAT1.	Glycine	34-41	solute carrier family 6 member 1	Homo sapiens	214-218
17049125-8	2006	However, glycine, which led to improved survival rate and liver function, significantly alleviated liver parenchyma cell damage by downregulating IRAK-4, TNF-alpha expression and NF-kappaB transcriptional activity compared with the control group.	Glycine	9-16	tumor necrosis factor	Homo sapiens	154-163
17089118-6	2006	One nonsynonymous SNP that substituted cysteine for glycine in the collagen-like domain of pig MBL-A was found by a multiplex PCR test in all European pig breeds examined, with allele frequencies ranging from 1.4 to 46.4%.	Glycine	52-59	mannose binding lectin 1	Sus scrofa	95-100
16990263-5	2006	The other AGT is a typical dipteran insect AGT and is specific for converting glyoxylic acid to glycine.	Glycine	96-103	angiotensinogen	Homo sapiens	10-13
16990263-5	2006	The other AGT is a typical dipteran insect AGT and is specific for converting glyoxylic acid to glycine.	Glycine	96-103	angiotensinogen	Homo sapiens	43-46
16945533-4	2006	Crystal structure of p38 in complex with 30 indicated a key pi-stacking interaction with the pendant tyrosine residue-35 in the glycine-rich loop.	Glycine	128-135	mitogen-activated protein kinase 14	Homo sapiens	21-24
16926147-9	2006	Mass spectrometric analysis suggested that the cleavage sites of Npr599 and InhA are the Asp(39)-Asp(40) and Gly(48)-Thr(49) bonds, respectively.	Glycine	109-112	inhibin alpha	Mus musculus	76-80
16797105-6	2006	Inhibition of thrombin, amounting to a 63.3% and 36.7% reduction in the rate of fibrin formation, was noted for cyclo(His-Ala) and cyclo(His-Gly), respectively.	Glycine	141-144	coagulation factor II, thrombin	Homo sapiens	14-22
16893894-7	2006	In Region I, residues Arg-748 and Phe-749 in TLR2 DD loop were involved in close contacts with Gly-676 in the TLR1 BB loop.	Glycine	95-98	toll like receptor 2	Homo sapiens	45-49
16893894-7	2006	In Region I, residues Arg-748 and Phe-749 in TLR2 DD loop were involved in close contacts with Gly-676 in the TLR1 BB loop.	Glycine	95-98	toll like receptor 1	Homo sapiens	110-114
16893894-8	2006	Because this model suggested that steric hindrance would significantly alter the binding interactions between DD loop of TLR2 and BB loop of TLR1, Gly-676 in TLR1 was rationally mutated to Ala and Leu.	Glycine	147-150	toll like receptor 2	Homo sapiens	121-125
16893894-8	2006	Because this model suggested that steric hindrance would significantly alter the binding interactions between DD loop of TLR2 and BB loop of TLR1, Gly-676 in TLR1 was rationally mutated to Ala and Leu.	Glycine	147-150	toll like receptor 1	Homo sapiens	141-145
16893894-8	2006	Because this model suggested that steric hindrance would significantly alter the binding interactions between DD loop of TLR2 and BB loop of TLR1, Gly-676 in TLR1 was rationally mutated to Ala and Leu.	Glycine	147-150	toll like receptor 1	Homo sapiens	158-162
16604304-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	6-13	solute carrier family 6 member 9	Homo sapiens	66-71
16957471-0	2006	A form of autosomal dominant spondyloepiphyseal dysplasia is caused by a glycine to alanine substitution in the COL2A1 gene.	Glycine	73-80	collagen type II alpha 1 chain	Homo sapiens	112-118
16957471-4	2006	We demonstrate that this dysplasia is due to a glycine to alanine substitution in the COL2A1 gene (p.Gly862Ala), thereby expanding the phenotypic spectrum of dysplasias associated with defects in type II collagen.	Glycine	47-54	collagen type II alpha 1 chain	Homo sapiens	86-92
16604304-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	6-13	solute carrier family 6 member 9	Homo sapiens	75-81
16604304-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	44-51	solute carrier family 6 member 9	Homo sapiens	66-71
16604304-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	44-51	solute carrier family 6 member 9	Homo sapiens	75-81
16780811-1	2006	BACKGROUND: Agonists at the N-methyl-D-aspartate (NMDA)-glycine site (D-serine, glycine, D-alanine and D-cycloserine) and glycine transporter-1 (GlyT-1) inhibitor (N-methylglycine, or called sarcosine) both improve the symptoms of stable chronic schizophrenia patients receiving concurrent antipsychotics.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	122-143
16912968-4	2006	With this combined approach we were able to detect nine calcium-dependent interactions between Arg-Gly-Ser-(RGS)-His6 tagged proteins derived from the library and GST-tagged S100B and S100A6, respectively.	Glycine	99-102	S100 calcium binding protein B	Homo sapiens	174-179
16912968-4	2006	With this combined approach we were able to detect nine calcium-dependent interactions between Arg-Gly-Ser-(RGS)-His6 tagged proteins derived from the library and GST-tagged S100B and S100A6, respectively.	Glycine	99-102	S100 calcium binding protein A6	Homo sapiens	184-190
16904076-2	2006	Details of interaction revealed that C-terminal ligand binding domain (LBD) of Nur77 specifically interacted with highly conserved glycine-rich loop of PKC required for catalytic activity.	Glycine	131-138	nuclear receptor subfamily 4 group A member 1	Homo sapiens	79-84
16904076-2	2006	Details of interaction revealed that C-terminal ligand binding domain (LBD) of Nur77 specifically interacted with highly conserved glycine-rich loop of PKC required for catalytic activity.	Glycine	131-138	proline rich transmembrane protein 2	Homo sapiens	152-155
16780811-1	2006	BACKGROUND: Agonists at the N-methyl-D-aspartate (NMDA)-glycine site (D-serine, glycine, D-alanine and D-cycloserine) and glycine transporter-1 (GlyT-1) inhibitor (N-methylglycine, or called sarcosine) both improve the symptoms of stable chronic schizophrenia patients receiving concurrent antipsychotics.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	145-151
16698014-5	2006	Subsequent sequencing of OPA1 identified a novel heterozygous missense mutation (c.1313A>G) replacing aspartic acid by glycine (p.D438G) in the GTPase domain of OPA1.	Glycine	119-126	OPA1 mitochondrial dynamin like GTPase	Homo sapiens	25-29
16907703-3	2006	The Ser49Gly polymorphism of the beta1 ADR was associated with resting heart rate in hypertensive African-Americans and hypertensive whites taking beta-blockers, with carriers of the Gly allele having a higher mean resting heart rate by 2.7 and 4.4 beats per minute (bpm), respectively.	Glycine	9-12	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	33-38
16954346-2	2006	We show that in mammalian fibroblasts, cytoplasmic linker protein (CLIP) 170 and other microtubule plus-end tracking proteins comprising a cytoskeleton-associated protein glycine-rich (CAP-Gly) microtubule binding domain such as CLIP-115 and p150 Glued, localize to the ends of tyrosinated microtubules but not to the ends of detyrosinated microtubules.	Glycine	171-178	CAP-Gly domain containing linker protein 2	Homo sapiens	229-237
16954346-2	2006	We show that in mammalian fibroblasts, cytoplasmic linker protein (CLIP) 170 and other microtubule plus-end tracking proteins comprising a cytoskeleton-associated protein glycine-rich (CAP-Gly) microtubule binding domain such as CLIP-115 and p150 Glued, localize to the ends of tyrosinated microtubules but not to the ends of detyrosinated microtubules.	Glycine	189-192	CAP-Gly domain containing linker protein 2	Homo sapiens	229-237
16698014-5	2006	Subsequent sequencing of OPA1 identified a novel heterozygous missense mutation (c.1313A>G) replacing aspartic acid by glycine (p.D438G) in the GTPase domain of OPA1.	Glycine	119-126	OPA1 mitochondrial dynamin like GTPase	Homo sapiens	161-165
16804045-0	2006	The A645D mutation in the hinge region of the human androgen receptor (AR) gene modulates AR activity, depending on the context of the polymorphic glutamine and glycine repeats.	Glycine	161-168	androgen receptor	Homo sapiens	52-69
16879614-5	2006	We found that Ki-1/57 and its putative paralog CGI-55 have two conserved Gly/Arg-rich motif clusters (RGG/RXR box, where X is any amino acid) that may be substrates for arginine-methylation by PRMT1.	Glycine	73-76	hyaluronan binding protein 4	Homo sapiens	14-21
16879614-5	2006	We found that Ki-1/57 and its putative paralog CGI-55 have two conserved Gly/Arg-rich motif clusters (RGG/RXR box, where X is any amino acid) that may be substrates for arginine-methylation by PRMT1.	Glycine	73-76	SERPINE1 mRNA binding protein 1	Homo sapiens	47-53
16804045-0	2006	The A645D mutation in the hinge region of the human androgen receptor (AR) gene modulates AR activity, depending on the context of the polymorphic glutamine and glycine repeats.	Glycine	161-168	androgen receptor	Homo sapiens	71-73
16804045-0	2006	The A645D mutation in the hinge region of the human androgen receptor (AR) gene modulates AR activity, depending on the context of the polymorphic glutamine and glycine repeats.	Glycine	161-168	androgen receptor	Homo sapiens	90-92
16635486-15	2006	The molecular identification and localisation of GLYT1 and ASCT2 in the lens suggests that these transporters may be responsible for the uptake of the precursor amino acids, glycine and glutamine, which are involved in GSH synthesis.	Glycine	174-181	solute carrier family 1 member 5	Rattus norvegicus	59-64
16938651-8	2006	The integrinalpha3beta(1) antagonists, anti-integrinbeta(1) monoclonal antibody and Gly-Arg-Gly-Asp (GRGD), decreased the expression of alpha-SMA protein and the percentage of alpha-SMA positive cells stimulated by TGF-beta(1) (both P &lt; 0.01).	Glycine	84-87	transforming growth factor, beta 1	Rattus norvegicus	215-226
16938651-8	2006	The integrinalpha3beta(1) antagonists, anti-integrinbeta(1) monoclonal antibody and Gly-Arg-Gly-Asp (GRGD), decreased the expression of alpha-SMA protein and the percentage of alpha-SMA positive cells stimulated by TGF-beta(1) (both P &lt; 0.01).	Glycine	92-95	transforming growth factor, beta 1	Rattus norvegicus	215-226
16964444-3	2006	The new Glra1 mutation appears to affect glycine"s inhibitory neurotransmission in the central nervous system (CNS) of the nmf11 homozygotes, which suffer from a severe startle disease-related phenotype and die by postnatal day 21.	Glycine	41-48	glycine receptor, alpha 1 subunit	Mus musculus	8-13
16964444-3	2006	The new Glra1 mutation appears to affect glycine"s inhibitory neurotransmission in the central nervous system (CNS) of the nmf11 homozygotes, which suffer from a severe startle disease-related phenotype and die by postnatal day 21.	Glycine	41-48	glycine receptor, alpha 1 subunit	Mus musculus	123-128
16725323-1	2006	Elevation of glycine levels by inhibition of the glycine transporter-1 (GlyT-1) and activation of the NMDA receptor is a potential strategy for the treatment of schizophrenia.	Glycine	13-20	solute carrier family 6 member 9	Homo sapiens	49-70
16725323-1	2006	Elevation of glycine levels by inhibition of the glycine transporter-1 (GlyT-1) and activation of the NMDA receptor is a potential strategy for the treatment of schizophrenia.	Glycine	13-20	solute carrier family 6 member 9	Homo sapiens	72-78
16671056-1	2006	Neurotensin(8-13) analogs containing a glycine or 5-aminovaleroyl spacer were labeled with fluorescein through formation of an N-terminal thiourea function.	Glycine	39-46	neurotensin	Homo sapiens	0-11
16713701-7	2006	However, affinity for and transepithelial transport via hPEPT1 were only seen for Gly-Sar-Sar, AsnPsi[CONCH(3)]PhePsi[CONCH(3)]Trp, and Gly-Sar-Leu.	Glycine	82-85	solute carrier family 15 member 1	Homo sapiens	56-62
16684766-2	2006	Protein spots that were specifically increased in the nfs1-14 mutant included subunits of lipoamide-containing enzyme complexes: Kgd2, Lat1, and Gcv3, subunits of the mitochondrial alpha-ketoglutarate dehydrogenase, pyruvate dehydrogenase, and glycine cleavage system complexes, respectively.	Glycine	244-251	cysteine desulfurase	Saccharomyces cerevisiae S288C	54-58
16938167-10	2006	CONCLUSIONS: Gly pretreatment could attenuate LPS -induced liver injury in mice, which may be associated with its role in down-regulating TLR4 expression and up-regulating IL-10 production.	Glycine	13-16	toll-like receptor 4	Mus musculus	138-142
16938167-10	2006	CONCLUSIONS: Gly pretreatment could attenuate LPS -induced liver injury in mice, which may be associated with its role in down-regulating TLR4 expression and up-regulating IL-10 production.	Glycine	13-16	interleukin 10	Mus musculus	172-177
16829701-1	2006	The nicotinic acetylcholine receptor (nAChR) is the prototypic member of the "Cys-loop" superfamily of ligand-gated ion channels which mediate synaptic neurotransmission, and whose other members include receptors for glycine, gamma-aminobutyric acid and serotonin.	Glycine	217-224	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	4-36
16829701-1	2006	The nicotinic acetylcholine receptor (nAChR) is the prototypic member of the "Cys-loop" superfamily of ligand-gated ion channels which mediate synaptic neurotransmission, and whose other members include receptors for glycine, gamma-aminobutyric acid and serotonin.	Glycine	217-224	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	38-43
16998534-1	2006	N-Myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the co-translational and (or) post-translational transfer of myristate to the amino terminal glycine residue of a number of important proteins, especially the non-receptor tyrosine kinases whose activity is important for tumorigenesis.	Glycine	171-178	N-myristoyltransferase 1	Homo sapiens	0-22
16998534-1	2006	N-Myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the co-translational and (or) post-translational transfer of myristate to the amino terminal glycine residue of a number of important proteins, especially the non-receptor tyrosine kinases whose activity is important for tumorigenesis.	Glycine	171-178	N-myristoyltransferase 1	Homo sapiens	24-27
16713701-7	2006	However, affinity for and transepithelial transport via hPEPT1 were only seen for Gly-Sar-Sar, AsnPsi[CONCH(3)]PhePsi[CONCH(3)]Trp, and Gly-Sar-Leu.	Glycine	136-139	solute carrier family 15 member 1	Homo sapiens	56-62
16639747-8	2006	The C-terminal carboxylate of DCEG glutathione"s glycine formed hydrogen bonds to Leu301 and Ser302, while the remaining interactions between DCEG and AR were hydrophobic, permitting significant flexibility of the AR and glutathione (GS) analogue interaction.	Glycine	49-56	aldo-keto reductase family 1 member B	Homo sapiens	214-216
16627568-6	2006	Gly-Sar and the drugs also modified the kinetics of hPEPT1 presteady-state charge movement, by causing a reduction in maximum charge (Qmax) and a shift of the midpoint voltage (V0.5) to more negative potentials.	Glycine	0-3	solute carrier family 15 member 1	Homo sapiens	52-58
16627568-8	2006	Based on steady-state and presteady-state analysis of Gly-Sar and cefadroxil transport, we proposed an extension of the 6-state kinetic model for hPEPT1 function that globally accounts for the observed presteady-state and steady-state kinetics of neutral dipeptide and drug transport.	Glycine	54-57	solute carrier family 15 member 1	Homo sapiens	146-152
16738539-8	2006	Furthermore, we clarified the mechanism of enhanced glycylsarcosine (Gly-Sar) transport activity in PEPT2-expressing HEK293 cells after the PDZK1 coexpression.	Glycine	69-72	solute carrier family 15 member 2	Homo sapiens	100-105
16738539-9	2006	This augmentation was accompanied by a significant increase in the V(max) of Gly-Sar transport via PEPT2 and it was also associated with the increased surface expression level of PEPT2.	Glycine	77-80	solute carrier family 15 member 2	Homo sapiens	99-104
16467955-1	2006	Two polymorphic trinucleotide repeats of human androgen receptor gene (hAR), CAG and GGN which encode glutamine and glycine, have been shown to be associated with human diseases.	Glycine	116-123	androgen receptor	Homo sapiens	47-64
16467955-1	2006	Two polymorphic trinucleotide repeats of human androgen receptor gene (hAR), CAG and GGN which encode glutamine and glycine, have been shown to be associated with human diseases.	Glycine	116-123	gametogenetin	Homo sapiens	85-88
16678126-3	2006	It appears that a Gly rich region (GRR) in the middle of the molecule serves as a "processing stop signal", though under certain conditions, such as after stimulation, p105 can be completely degraded.	Glycine	18-21	nuclear factor kappa B subunit 1	Homo sapiens	168-172
16754718-6	2006	Thus, violation of the conserved preference for tyrosine and glycine in D(H) RF1 alters CDR-H3 content and impairs B cell development and antibody production.	Glycine	61-68	retroperitoneal fat pad weight 1	Mus musculus	77-80
16597625-8	2006	Sequence alignments of various AspRSs allowed placing Gly-269 at a position occupied by Asp-220, the residue contacting G73 in the crystallographic structure of E. coli AspRS-tRNA(Asp) complex.	Glycine	54-57	aspartyl-tRNA synthetase 2, mitochondrial	Homo sapiens	31-36
16597625-9	2006	Replacing this glycine by an aspartate renders human mt-AspRS more discriminative to G73.	Glycine	15-22	aspartyl-tRNA synthetase 2, mitochondrial	Homo sapiens	56-61
16699006-2	2006	A Gly-Arg-rich region between amino acids 325 and 376 is required for both the segregation and transcriptional activation functions of EBNA1.	Glycine	2-5	EBNA-1	Human gammaherpesvirus 4	135-140
16595170-6	2006	In contrast, the Arg(3.50) to Gly mutation found in hamster GPR33 inactivates the receptor and may have contributed to pseudogenization of this gene in this species.	Glycine	30-33	G protein-coupled receptor 33	Homo sapiens	60-65
16631115-5	2006	The cDNA of PGC-1alpha variant bearing either glycine or serine at 482 codon was transfected into Chang human hepatocyte cells.	Glycine	46-53	PPARG coactivator 1 alpha	Homo sapiens	12-22
16631115-6	2006	The PGC-1alpha protein bearing glycine had impaired coactivator activity on Tfam promoter-mediated luciferase.	Glycine	31-38	PPARG coactivator 1 alpha	Homo sapiens	4-14
16631115-6	2006	The PGC-1alpha protein bearing glycine had impaired coactivator activity on Tfam promoter-mediated luciferase.	Glycine	31-38	transcription factor A, mitochondrial	Homo sapiens	76-80
16631115-10	2006	These results suggest that PGC-1alpha variants with Gly/Gly at 482nd amino acid may impair the Tfam transcription, a regulatory function of mitochondrial biogenesis, resulting in dysfunctional mtDNA replication.	Glycine	52-55	PPARG coactivator 1 alpha	Homo sapiens	27-37
16631115-10	2006	These results suggest that PGC-1alpha variants with Gly/Gly at 482nd amino acid may impair the Tfam transcription, a regulatory function of mitochondrial biogenesis, resulting in dysfunctional mtDNA replication.	Glycine	52-55	transcription factor A, mitochondrial	Homo sapiens	95-99
16631115-10	2006	These results suggest that PGC-1alpha variants with Gly/Gly at 482nd amino acid may impair the Tfam transcription, a regulatory function of mitochondrial biogenesis, resulting in dysfunctional mtDNA replication.	Glycine	56-59	PPARG coactivator 1 alpha	Homo sapiens	27-37
16631115-10	2006	These results suggest that PGC-1alpha variants with Gly/Gly at 482nd amino acid may impair the Tfam transcription, a regulatory function of mitochondrial biogenesis, resulting in dysfunctional mtDNA replication.	Glycine	56-59	transcription factor A, mitochondrial	Homo sapiens	95-99
16624262-1	2006	OBJECTIVE: In vitro experiments have shown that the ryanodine receptor-2 (RyR2) central domain peptide DPc10 (Gly(2460)-Pro(2495)) mimics channel dysfunction associated with catecholaminergic polymorphic ventricular tachycardia (CPVT) by acting competitively to reduce stabilizing interactions between the N-terminal and central domains.	Glycine	110-113	ryanodine receptor 2	Homo sapiens	52-72
16624262-1	2006	OBJECTIVE: In vitro experiments have shown that the ryanodine receptor-2 (RyR2) central domain peptide DPc10 (Gly(2460)-Pro(2495)) mimics channel dysfunction associated with catecholaminergic polymorphic ventricular tachycardia (CPVT) by acting competitively to reduce stabilizing interactions between the N-terminal and central domains.	Glycine	110-113	ryanodine receptor 2	Homo sapiens	74-78
16704222-5	2006	In a separate experiment, insulin was modified by formaldehyde (CH2O vs CD2O) and glycine.	Glycine	82-89	insulin	Homo sapiens	26-33
16670331-4	2006	With mouse MD-2 mutants, we show in this study that Gly(59) was found to be a novel critical amino acid for LPS binding outside the region 119-132.	Glycine	52-55	toll-like receptor 4	Mus musculus	108-111
16670331-7	2006	MD-2 mutants substituting alanine for Phe(126) or Gly(129) impaired LPS-induced TLR4 clustering, but not LPS binding to TLR4/MD-2, demonstrating that ligand-induced receptor clustering is differentially regulated by MD-2 from ligand binding.	Glycine	50-53	toll-like receptor 4	Mus musculus	68-71
16670331-7	2006	MD-2 mutants substituting alanine for Phe(126) or Gly(129) impaired LPS-induced TLR4 clustering, but not LPS binding to TLR4/MD-2, demonstrating that ligand-induced receptor clustering is differentially regulated by MD-2 from ligand binding.	Glycine	50-53	toll-like receptor 4	Mus musculus	80-84
16828040-5	2006	Moreover, mutation of a conserved glycine residue into an arginine residue in FXYD2 has been linked to cases of human hypomagnesemia indicating that dysregulation of Na,K-ATPase by FXYD proteins may be implicated in pathophysiological states.	Glycine	34-41	FXYD domain containing ion transport regulator 2	Homo sapiens	78-83
16596676-6	2006	This mutation is predicted to lead to the exchange of a highly conserved glycine residue at position 1,728 by cysteine (G1728C) in repeat 15 of the filamin A rod domain.	Glycine	73-80	filamin A	Homo sapiens	148-157
16619030-6	2006	Remarkably, the mutant p105 that lacks the internal region including the glycine-rich region (GRR) is completely degraded by 20S proteasome in vitro.	Glycine	73-80	nuclear factor kappa B subunit 1	Homo sapiens	23-27
16672662-7	2006	Fluctuation analysis of membrane current, induced by glycine application to outside-out patches, showed that mean single-channel conductance was increased in spa/spa (64.2 +/- 4.9 vs 36.1 +/- 1.4 pS), but unchanged in spd/spd (32.4 +/- 2.1 vs 35.3 +/- 2.1 pS).	Glycine	53-60	glycine receptor, beta subunit	Mus musculus	158-161
16672662-7	2006	Fluctuation analysis of membrane current, induced by glycine application to outside-out patches, showed that mean single-channel conductance was increased in spa/spa (64.2 +/- 4.9 vs 36.1 +/- 1.4 pS), but unchanged in spd/spd (32.4 +/- 2.1 vs 35.3 +/- 2.1 pS).	Glycine	53-60	glycine receptor, beta subunit	Mus musculus	162-165
16651734-13	2006	The pH-profile of the transport activity in CHO/hPEPT1 cells treated with DEPC in the presence of 10 mM Gly-Sar also showed a bell-shape similar to that in non-treated CHO/hPEPT1 cells.	Glycine	104-107	solute carrier family 15 member 1	Homo sapiens	48-54
16651734-13	2006	The pH-profile of the transport activity in CHO/hPEPT1 cells treated with DEPC in the presence of 10 mM Gly-Sar also showed a bell-shape similar to that in non-treated CHO/hPEPT1 cells.	Glycine	104-107	solute carrier family 15 member 1	Homo sapiens	172-178
16704222-9	2006	Furthermore, eight out of the sixteen potentially reactive sites of the insulin molecule were modified by incubation with formaldehyde and glycine.	Glycine	139-146	insulin	Homo sapiens	72-79
16155195-1	2006	BACKGROUND: The majority of COL2A1 missense mutations are substitutions of obligatory glycine residues in the triple helical domain.	Glycine	86-93	collagen type II alpha 1 chain	Homo sapiens	28-34
16503403-2	2006	The soluble factor lysophosphatidic acid (LPA) acts through Rho GTPase and its effector Rho kinase (ROCK) to enhance alpha5beta1 integrin-mediated cell spreading on the Arg-Gly-Asp (RGD) cell-binding domain of FN.	Glycine	173-176	fibronectin 1	Homo sapiens	210-212
16584196-12	2006	Both the Lys 79 --&gt; Ala and Asn 52 --&gt; Gly mutations are expected to affect the buried hydrogen bond network of cytochrome c, suggesting that this network is an important modulator of the acid unfolding of cytochrome c.	Glycine	45-48	cytochrome c, somatic	Homo sapiens	118-130
16618113-13	2006	These data show that glycine 553 is important for protein trafficking and are consistent with, but do not yet prove, its involvement in ABCG2 homodimerization.	Glycine	21-28	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	136-141
16568107-5	2006	In addition, hPepT1 activity was likely to be coupled to a Na+/H+ exchanger, as evidenced by the fact that [14C]Gly-Sar uptake was not affected by the absence of Na+ when cells were incubated at low pH (5.2).	Glycine	112-115	solute carrier family 15 member 1	Homo sapiens	13-19
16540482-3	2006	The lba1 mutant of Arabidopsis thaliana with a Gly(851)--&gt;Glu missense mutation in AtUPF1 yielded seeds that were on average 22% longer in the long axis and 35% heavier than the wild-type Col seeds.	Glycine	47-50	RNA helicase	Arabidopsis thaliana	4-8
16540482-3	2006	The lba1 mutant of Arabidopsis thaliana with a Gly(851)--&gt;Glu missense mutation in AtUPF1 yielded seeds that were on average 22% longer in the long axis and 35% heavier than the wild-type Col seeds.	Glycine	47-50	RNA helicase	Arabidopsis thaliana	86-92
16516863-8	2006	VGLUT3 was present in glycine-releasing amacrine cells in rat retina but was restricted to a few ganglion cells in human retina.	Glycine	22-29	solute carrier family 17 member 8	Rattus norvegicus	0-6
16584196-1	2006	The kinetics and thermodynamics of the alkaline and acid conformational transitions of a Lys 79 --&gt; Ala/Asn 52 --&gt; Gly (A79G52) variant of iso-1-cytochrome c are studied.	Glycine	121-124	cytochrome c, somatic	Homo sapiens	151-163
16584196-12	2006	Both the Lys 79 --&gt; Ala and Asn 52 --&gt; Gly mutations are expected to affect the buried hydrogen bond network of cytochrome c, suggesting that this network is an important modulator of the acid unfolding of cytochrome c.	Glycine	45-48	cytochrome c, somatic	Homo sapiens	212-224
16046221-4	2006	We here report that a recently identified genetic variant, c.553G&gt;T in the APOA5 gene which causes a substitution of a cysteine for a glycine residue at amino acid residue 185(G185C) is also associated with increased TG levels.	Glycine	137-144	apolipoprotein A5	Homo sapiens	78-83
16479534-5	2006	In the case of calpain-2, a single iteration step involving LC-MS, provided the definitive residue specificity from which a highly sensitive fluorogenic substrate, (FAM)-Gly-Gly-Gly-Gln-Leu-Tyr-Gly-Gly-DPA-Arg-Arg-Lys-(TAMRA), was then designed.	Glycine	170-173	calpain 2	Homo sapiens	15-24
16328452-5	2006	Uptake of the PepT1 substrate glycylsarcosine [(3)H]-Gly-Sar was studied in vitro in the human colon carcinoma cell line Caco2/bbe monolayers as well as in vivo in mice injected with cytokines.	Glycine	53-56	solute carrier family 15 member 1	Homo sapiens	14-19
16328452-9	2006	TNF-alpha and IFN-gamma, but not IL-1beta, increased Gly-Sar uptake in mouse proximal and distal colon; however, no changes were observed in the small intestine with any cytokine treatment.	Glycine	53-56	tumor necrosis factor	Mus musculus	0-9
16328452-9	2006	TNF-alpha and IFN-gamma, but not IL-1beta, increased Gly-Sar uptake in mouse proximal and distal colon; however, no changes were observed in the small intestine with any cytokine treatment.	Glycine	53-56	interferon gamma	Mus musculus	14-23
16283203-7	2006	Moreover, PEPT1 mRNA level was positively related to the activity of [(14)C]Gly-Sar uptake (r=0.55).	Glycine	76-79	solute carrier family 15 member 1	Homo sapiens	10-15
16283203-9	2006	With this improved model, Gly-Sar transport in clones 1 and 9 was well-predicted, suggesting that our model can simulate Gly-Sar transport in cells expressing PEPT1 at different levels.	Glycine	26-29	solute carrier family 15 member 1	Homo sapiens	159-164
16283203-9	2006	With this improved model, Gly-Sar transport in clones 1 and 9 was well-predicted, suggesting that our model can simulate Gly-Sar transport in cells expressing PEPT1 at different levels.	Glycine	121-124	solute carrier family 15 member 1	Homo sapiens	159-164
16479534-5	2006	In the case of calpain-2, a single iteration step involving LC-MS, provided the definitive residue specificity from which a highly sensitive fluorogenic substrate, (FAM)-Gly-Gly-Gly-Gln-Leu-Tyr-Gly-Gly-DPA-Arg-Arg-Lys-(TAMRA), was then designed.	Glycine	174-177	calpain 2	Homo sapiens	15-24
16407238-1	2006	Differential scanning calorimetry was used to measure changes in thermodynamic stability and aggregation for glycine 93 mutants of human copper, zinc-superoxide dismutase (SOD).	Glycine	109-116	superoxide dismutase 1	Homo sapiens	145-170
16548523-2	2006	We previously showed that hypochlorous acid (HOCl), a specific product of myeloperoxidase, inactivates matrilysin by modifying adjacent tryptophan and glycine (WG) residues in the catalytic domain.	Glycine	151-158	myeloperoxidase	Homo sapiens	74-89
16516209-2	2006	Site-directed mutants of the redox-active Cys-Gly-His-Cys motif within an isolated ERp57 sub-domain have been studied.	Glycine	46-49	protein disulfide isomerase family A member 3	Homo sapiens	83-88
16407238-1	2006	Differential scanning calorimetry was used to measure changes in thermodynamic stability and aggregation for glycine 93 mutants of human copper, zinc-superoxide dismutase (SOD).	Glycine	109-116	superoxide dismutase 1	Homo sapiens	172-175
16337740-6	2006	Interestingly, a single nucleotide mutation, changing amino acid 482 from arginine to threonine or glycine in ABCG2, results in a major increase in the catalytic activity and a wider drug recognition by this protein.	Glycine	99-106	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	110-115
16431218-2	2006	Substituting smaller amino acids (alanine [Ala (A)] or glycine [Gly (G)]) for glutamine [Gln (Q)] in subdomain V drastically increased the susceptibility of ERK1/2 to 1-naphthyl PP1 (1NA-PP1).	Glycine	55-62	mitogen-activated protein kinase 3	Homo sapiens	157-163
16442704-0	2006	Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.	Glycine	0-7	AKT serine/threonine kinase 1	Homo sapiens	93-96
16442704-0	2006	Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.	Glycine	0-7	mitogen-activated protein kinase 8	Homo sapiens	101-104
16431218-2	2006	Substituting smaller amino acids (alanine [Ala (A)] or glycine [Gly (G)]) for glutamine [Gln (Q)] in subdomain V drastically increased the susceptibility of ERK1/2 to 1-naphthyl PP1 (1NA-PP1).	Glycine	64-67	mitogen-activated protein kinase 3	Homo sapiens	157-163
16507366-4	2006	We found a somatic mutation and a gene variation in human lung cancer cells that change glycine to cysteine in the DGR domain, introducing local conformational changes that reduce Keap1"s affinity for Nrf2.	Glycine	88-95	kelch like ECH associated protein 1	Homo sapiens	180-185
16635399-5	2006	RESULTS: Concentration of intracellular calcium and production of TNF-alpha by isolated Kupffer cells stimulated by LPS were elevated significantly in the rats with hemorrhagic shock, which were totally prevented by glycine + MP compared with other groups (P &lt; 0.005).	Glycine	216-223	tumor necrosis factor	Rattus norvegicus	66-75
16507366-4	2006	We found a somatic mutation and a gene variation in human lung cancer cells that change glycine to cysteine in the DGR domain, introducing local conformational changes that reduce Keap1"s affinity for Nrf2.	Glycine	88-95	NFE2 like bZIP transcription factor 2	Homo sapiens	201-205
16417568-0	2006	Protein kinase C enhances glycine-insensitive desensitization of NMDA receptors independently of previously identified protein kinase C sites.	Glycine	26-33	proline rich transmembrane protein 2	Homo sapiens	0-16
16417568-6	2006	When co-expressing NR1(stop838)/NR2A the effects of PMA could only be observed with agonist concentrations sufficient to induce glycine-insensitive desensitization.	Glycine	128-135	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	19-22
16417568-6	2006	When co-expressing NR1(stop838)/NR2A the effects of PMA could only be observed with agonist concentrations sufficient to induce glycine-insensitive desensitization.	Glycine	128-135	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	32-36
16417568-10	2006	We conclude that activation of PKC increases NMDAR glycine-insensitive desensitization independently of previously identified sites located within the NR1 C-terminus and distal segment of the NR2A C-terminus.	Glycine	51-58	proline rich transmembrane protein 2	Homo sapiens	31-34
16841561-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	6-13	solute carrier family 6 member 9	Homo sapiens	66-71
16841561-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	6-13	solute carrier family 6 member 9	Homo sapiens	75-81
16841561-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	44-51	solute carrier family 6 member 9	Homo sapiens	66-71
16841561-2	2006	Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake into nerve terminals.	Glycine	44-51	solute carrier family 6 member 9	Homo sapiens	75-81
16635399-6	2006	CONCLUSIONS: The combination of glycine and MP prevents the increase of intracellular calcium of Kupffer cell, suppress Kupffer cell activation, decrease the production of TNF-alpha of Kupffer cell and block systemic inflammatory responses more effectively than single administer of glycine or MP.	Glycine	32-39	tumor necrosis factor	Rattus norvegicus	172-181
16436205-2	2006	Mice expressing a glycine --&gt; alanine substitution in cytosolic Cu, Zn-superoxide dismutase (G93A-SOD1) associated with familial amyotrophic lateral sclerosis (ALS) demonstrate age-dependent neuroinflammation associated with broad-spectrum cytokine, eicosanoid and oxidant production.	Glycine	18-25	superoxide dismutase 1, soluble	Mus musculus	101-105
16330545-8	2006	The novel formyl-Met-Asp-Gly-Cys-Glu-Leu peptide ligand is not only a valuable experimental tool but has also a potential role in antimetastatic treatment of the 50% of human breast cancer patients that have reduced endogenous Wnt-5a protein expression.	Glycine	25-28	Wnt family member 5A	Homo sapiens	227-233
16427628-2	2006	We showed that all RET-PTC-1 mutants in which the C in this motif (C376) was replaced with glycine, lysine, threonine or serine lost their activity in vitro.	Glycine	91-98	patched 1	Homo sapiens	23-28
16309674-2	2006	There is evidence that mutations in the Cu/Zn superoxide dismutase (SOD1) gene are implicated in about 20% of familiar ALS and transgenic mice overexpressing the human Cu/Zn superoxide dismutase (GLY(93) --&gt; ALA) mutation show an ALS-like phenotype.	Glycine	196-199	superoxide dismutase 1	Homo sapiens	40-66
16309674-2	2006	There is evidence that mutations in the Cu/Zn superoxide dismutase (SOD1) gene are implicated in about 20% of familiar ALS and transgenic mice overexpressing the human Cu/Zn superoxide dismutase (GLY(93) --&gt; ALA) mutation show an ALS-like phenotype.	Glycine	196-199	superoxide dismutase 1, soluble	Mus musculus	68-72
16309674-2	2006	There is evidence that mutations in the Cu/Zn superoxide dismutase (SOD1) gene are implicated in about 20% of familiar ALS and transgenic mice overexpressing the human Cu/Zn superoxide dismutase (GLY(93) --&gt; ALA) mutation show an ALS-like phenotype.	Glycine	196-199	superoxide dismutase 1	Homo sapiens	168-194
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	cell migration inducing hyaluronidase 1	Homo sapiens	68-76
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	FAM3 metabolism regulating signaling molecule A	Homo sapiens	195-200
16638323-1	2006	OBJECTIVE: Osteogenesis imperfecta (OI) is a congenital disease of connective tissue of increased bone fragility and low bone mass, most often caused by single amino acid substitution of glycine residues in the collagen, type I, alpha 1 protein (COL1A1) gene or the collagen, type I, alpha 2 protein (COL1A2) gene, encoding type I procollagen chains.	Glycine	187-194	collagen type I alpha 2 chain	Homo sapiens	301-307
16638323-1	2006	OBJECTIVE: Osteogenesis imperfecta (OI) is a congenital disease of connective tissue of increased bone fragility and low bone mass, most often caused by single amino acid substitution of glycine residues in the collagen, type I, alpha 1 protein (COL1A1) gene or the collagen, type I, alpha 2 protein (COL1A2) gene, encoding type I procollagen chains.	Glycine	187-194	collagen type I alpha 2 chain	Homo sapiens	324-342
17028433-9	2006	Liver tissue levels of tumor necrosis factor (TNF)alpha were reduced only in the glycine group whereas TNFalpha was increased in the untreated as well as the LA group.	Glycine	81-88	tumor necrosis factor	Rattus norvegicus	46-55
16157451-7	2006	After adjustment for age, gender, and the APOE varepsilon4 carrier status, the odds ratio for the development of LOAD associated with the Asp/Gly and Gly/Gly versus Asp/Asp genotype was 0.37 (95% CI: 0.20-0.69, P=0.002).	Glycine	150-153	apolipoprotein E	Homo sapiens	42-46
16157451-7	2006	After adjustment for age, gender, and the APOE varepsilon4 carrier status, the odds ratio for the development of LOAD associated with the Asp/Gly and Gly/Gly versus Asp/Asp genotype was 0.37 (95% CI: 0.20-0.69, P=0.002).	Glycine	150-153	apolipoprotein E	Homo sapiens	42-46
16364156-8	2006	The PHO stimulated IgE showed a nonspecific binding to ImmunoCAP with common allergens and glycine background ImmunoCAP that was up to 10-fold higher than that of monomeric myeloma-IgE at twice the concentration.	Glycine	91-98	immunoglobulin heavy constant epsilon	Homo sapiens	19-22
16454681-2	2006	Based on its tissue distribution, GlyT-1 has been suggested to co-localise with the NMDA receptor where it may modulate the concentration of glycine at its co-agonist binding site.	Glycine	141-148	solute carrier family 6 member 9	Homo sapiens	34-40
16454681-7	2006	Pharmacological data for the GlyT-1 inhibitors Org 24598 and ALX 5407 obtained using this novel electrogenic assay correlated well with the conventional [(3)H]-glycine uptake assay format.	Glycine	160-167	solute carrier family 6 member 9	Homo sapiens	29-35
16611082-2	2006	The transport of glycine in glutamatergic synapse is carried out by glycine transporter-1 (GlyT1), a Na+/Cl(-)-dependent carrier molecule.	Glycine	17-24	solute carrier family 6 member 9	Homo sapiens	68-89
16611082-2	2006	The transport of glycine in glutamatergic synapse is carried out by glycine transporter-1 (GlyT1), a Na+/Cl(-)-dependent carrier molecule.	Glycine	17-24	solute carrier family 6 member 9	Homo sapiens	91-96
16611082-3	2006	The primary role of GlyT1 is to maintain glycine concentrations below saturation level at postsynaptic NMDA receptors.	Glycine	41-48	solute carrier family 6 member 9	Homo sapiens	20-25
16611082-5	2006	GlyT1 operates bidirectionally: it decreases synaptic glycine concentration when operates in normal mode and releases glycine from glial cells as operates in a reverse mode.	Glycine	54-61	solute carrier family 6 member 9	Homo sapiens	0-5
16611082-5	2006	GlyT1 operates bidirectionally: it decreases synaptic glycine concentration when operates in normal mode and releases glycine from glial cells as operates in a reverse mode.	Glycine	118-125	solute carrier family 6 member 9	Homo sapiens	0-5
16611082-8	2006	The first promising in vitro and in vivo experiments with glycine itself, and its N-methyl analogue, sarcosine, had initiated the syntheses of potential GlyT1 inhibitors with more complex structures, in which, however, the glycine or sarcosine moiety had always been incorporated.	Glycine	58-65	solute carrier family 6 member 9	Homo sapiens	153-158
17028433-10	2006	Levels of TNFalpha mRNA were upregulated in both the glycine- and LA-pretreated groups.	Glycine	53-60	tumor necrosis factor	Rattus norvegicus	10-18
17028433-11	2006	CONCLUSION: Our data show that increased animal survival by glycine was accompanied by a reduced TNFalpha content in liver tissue.	Glycine	60-67	tumor necrosis factor	Rattus norvegicus	97-105
17028433-12	2006	Protection by glycine is likely to result from a reduction in adverse TNFalpha effects.	Glycine	14-21	tumor necrosis factor	Rattus norvegicus	70-78
16363805-10	2005	Also, a mutant recombinant fibrinogen modeled after the naturally occurring variant Osaka V (gammaArg375 --&gt; Gly) showed delayed clot retraction and reduced binding to purified alpha(IIb)beta3.	Glycine	112-115	fibrinogen beta chain	Homo sapiens	27-37
16304625-9	2005	Strongly labeled Gly-ir cells predominate in all nuclei, their total number ranging between 9,400 in Vp to 24,300 in Vip and 34,200 in Vc.	Glycine	17-20	vasoactive intestinal peptide	Rattus norvegicus	117-120
16355270-17	2006	Conversely, FHL2 stimulation of CREB activity was dependent on integrin function because it was inhibited by Gly-Arg-Gly-Asp-Ser (GRGDS) peptide.	Glycine	109-112	four and a half LIM domains 2	Mus musculus	12-16
16355270-17	2006	Conversely, FHL2 stimulation of CREB activity was dependent on integrin function because it was inhibited by Gly-Arg-Gly-Asp-Ser (GRGDS) peptide.	Glycine	109-112	cAMP responsive element binding protein 1	Mus musculus	32-36
18221190-3	2006	One possible strategy is to increase synaptic levels of glycine by blocking the glycine transporter-1 (GlyT-1) in glia cells, since glycine acts as a co-agonist site on the NMDA receptor.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	80-101
18221190-3	2006	One possible strategy is to increase synaptic levels of glycine by blocking the glycine transporter-1 (GlyT-1) in glia cells, since glycine acts as a co-agonist site on the NMDA receptor.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	103-109
18221190-3	2006	One possible strategy is to increase synaptic levels of glycine by blocking the glycine transporter-1 (GlyT-1) in glia cells, since glycine acts as a co-agonist site on the NMDA receptor.	Glycine	80-87	solute carrier family 6 member 9	Homo sapiens	103-109
16287466-9	2005	While pro-apoptotic Bax and caspase-3 were down-regulated, Bcl-2 was up-regulated in the glycine-treated group.	Glycine	89-96	BCL2, apoptosis regulator	Rattus norvegicus	59-64
16263090-5	2005	Characterization of the FGF3 binding domain of rpS2 showed that both the Arg-Gly-rich N-terminal region and a short carboxyl-terminal sequence of rpS2 are necessary for FGF3 binding.	Glycine	77-80	ribosomal protein S2	Homo sapiens	47-51
15979761-0	2005	Recombinant prohormone convertase 1 and 2 cleave purified pro cholecystokinin (CCK) and a synthetic peptide containing CCK 8 Gly Arg Arg and the carboxyl-terminal flanking peptide.	Glycine	125-128	cholecystokinin	Homo sapiens	119-122
16287139-9	2005	This reveals a modifying role for the serine-glycine-rich region in CITED2 function.	Glycine	45-52	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2	Homo sapiens	68-74
16301672-6	2005	This cytolysis was repressed by the cytoprotectant glycine, permitting dissociation of P2X7R-regulated secretion of mature IL-1beta from the lytic release of pro-IL-1beta.	Glycine	51-58	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	87-92
16301672-6	2005	This cytolysis was repressed by the cytoprotectant glycine, permitting dissociation of P2X7R-regulated secretion of mature IL-1beta from the lytic release of pro-IL-1beta.	Glycine	51-58	interleukin 1 beta	Mus musculus	123-131
16301672-6	2005	This cytolysis was repressed by the cytoprotectant glycine, permitting dissociation of P2X7R-regulated secretion of mature IL-1beta from the lytic release of pro-IL-1beta.	Glycine	51-58	interleukin 1 beta	Mus musculus	162-170
16317684-6	2005	Madin Darby canine kidney cells coexpressing mouse Ostalpha and Ostbeta exhibited enhanced apical to basolateral transport of the major glycine and taurine conjugated bile acid species.	Glycine	136-143	solute carrier family 51, beta subunit	Mus musculus	64-71
16604470-0	2005	The glycine residues G551 and G1349 within the ATP-binding cassette signature motifs play critical roles in the activation and inhibition of cystic fibrosis transmembrane conductance regulator channels by phloxine B.	Glycine	4-11	CF transmembrane conductance regulator	Homo sapiens	141-192
16478048-3	2005	In this study, we isolated an F-box protein gene from soybean, which shares significant homology with the Arabidopsis COI1 and similarly contains an F-box motif and leucine rich repeats (LRR), here designated GmCOI1 (Glycine max L.	Glycine	217-224	RNI-like superfamily protein	Arabidopsis thaliana	118-122
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	117-120	cholecystokinin	Homo sapiens	110-113
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	180-183	cholecystokinin	Homo sapiens	110-113
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	180-183	cholecystokinin	Homo sapiens	174-177
16344603-7	2005	Indeed, glycine prevents alcohol-induced liver injury in a long-term enteral ethanol feeding rats (Tsukamoto-French) by decreasing production of TNF-alpha in the liver.	Glycine	8-15	tumor necrosis factor	Rattus norvegicus	145-154
16199006-7	2005	Non-specific binding is predominantly a function of the PTD and greatly increases by substitution of a non-polar glycine with a negatively charged glutamate in the PTD HA2.	Glycine	113-120	keratin 32	Homo sapiens	168-171
16281028-4	2005	Here we report crystal structures of the ligand-binding core of NR2A with glutamate and that of the NR1-NR2A heterodimer with glutamate and glycine.	Glycine	140-147	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	100-103
16281028-4	2005	Here we report crystal structures of the ligand-binding core of NR2A with glutamate and that of the NR1-NR2A heterodimer with glutamate and glycine.	Glycine	140-147	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	104-108
16281028-2	2005	These receptors are heteromeric ion channels that for activation require binding of glycine and glutamate to the NR1 and NR2 subunits, respectively.	Glycine	84-91	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	113-116
16293771-10	2005	OPN significantly reduced the STZ-induced NO levels in the islets through an Arg-Gly-Asp (RGD)-dependent reduction of inducible NO synthase (iNOS) mRNA levels.	Glycine	81-84	nitric oxide synthase 2	Rattus norvegicus	118-139
16272569-1	2005	A cyclic chimeric dodecapeptide (cCD) mimicking the conformation-specific domains of CCR5 and CXCR4 was prepared in which Gly-Asp links the amino and carboxyl termini of two combined pentapeptides (S169-G173 of CCR5; E179-R183 of CXCR4) derived from human immunodeficiency virus type-1 (HIV-1) coreceptors.	Glycine	122-125	chemokine (C-C motif) receptor 5	Mus musculus	85-89
16272569-1	2005	A cyclic chimeric dodecapeptide (cCD) mimicking the conformation-specific domains of CCR5 and CXCR4 was prepared in which Gly-Asp links the amino and carboxyl termini of two combined pentapeptides (S169-G173 of CCR5; E179-R183 of CXCR4) derived from human immunodeficiency virus type-1 (HIV-1) coreceptors.	Glycine	122-125	chemokine (C-C motif) receptor 5	Mus musculus	211-215
16293771-10	2005	OPN significantly reduced the STZ-induced NO levels in the islets through an Arg-Gly-Asp (RGD)-dependent reduction of inducible NO synthase (iNOS) mRNA levels.	Glycine	81-84	nitric oxide synthase 2	Rattus norvegicus	141-145
16143353-1	2005	The neurotransmitter glycine is removed from the synaptic cleft by two Na(+)-and Cl(-)-dependent transporters: GLYT1 and GLYT2.	Glycine	21-28	solute carrier family 6 member 9	Homo sapiens	111-116
16373326-6	2005	When expressed heterologously in a mammalian cell line, rabbit PAT1 mediates pH-dependent, Na(+)-independent uptake of proline, glycine, l-alanine and alpha-(methylamino)isobutyric acid.	Glycine	128-135	proton-coupled amino acid transporter 1	Oryctolagus cuniculus	63-67
16143353-2	2005	GLYT1, expressed in glial processes of glycinergic areas and in glia and neurons of glutamatergic pathways that contain N-methyl-d-aspartate (NMDA) receptors, is essential for regulating glycine levels both at glycinergic and NMDA-containing synapses.	Glycine	39-46	solute carrier family 6 member 9	Homo sapiens	0-5
16181645-1	2005	Evidence is accumulating that the glycine transporter GLYT1 regulates NMDA receptor function by modulating the glycine concentration in glutamatergic synapses.	Glycine	34-41	solute carrier family 6 member 9	Homo sapiens	54-59
16221850-8	2005	The effect of endogenous glycine could be observed only after simultaneous removal of endogenous D-serine and blockage of the glycine transporter GlyT1.	Glycine	25-32	solute carrier family 6 member 9	Homo sapiens	146-151
16150419-4	2005	A construct in which the cyclohydrolase activity of NMDMC was inactivated by point mutation also rescued the glycine auxotrophy, although poorly.	Glycine	109-116	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase	Mus musculus	52-57
16215634-2	2005	Moreover, its corresponding position is always occupied by a Gly residue in other members of insulin superfamily.	Glycine	61-64	insulin	Homo sapiens	93-100
16215634-9	2005	The present results suggest that Gly is likely the only applicable natural amino acid for the B8 position of insulin where both foldability and activity are concerned.	Glycine	33-36	insulin	Homo sapiens	109-116
15885796-5	2005	In SOD1(-)/G93A(-) or SOD1(+) mice GLY evoked [3H]d-ASP and [3H]GABA release, while GABA caused [3H]d-ASP, but not [3H]GLY, release.	Glycine	35-38	superoxide dismutase 1, soluble	Mus musculus	3-7
16033814-6	2005	Inclusion of the arginine-glycine-aspartic but not the arginine-glycine-glutamic peptide to neutrophil cultures blocked uPA kringle-induced potentiation of proinflammatory responses, demonstrating that interactions between the KD and integrins were involved.	Glycine	26-33	plasminogen activator, urokinase	Homo sapiens	120-123
16150047-4	2005	To the C-terminal part of recombinant staphylokinase (r-SAK), which is a promising profibrinolytic agent, we assembled: (i) the Kringle 2 domain (K2) of tissue-type plasminogen activator (t-PA), containing a fibrin-specific binding site, (ii) the RGD sequence (Arg-Gly-Asp) for the prevention of platelet aggregation and (iii) the antithrombotic agent - hirudin.	Glycine	265-268	plasminogen activator, tissue type	Homo sapiens	153-186
16199870-0	2005	The amino-terminal region of Drosophila MSL1 contains basic, glycine-rich, and leucine zipper-like motifs that promote X chromosome binding, self-association, and MSL2 binding, respectively.	Glycine	61-68	male-specific lethal 1	Drosophila melanogaster	40-44
16199870-7	2005	A glycine-rich motif between the basic and leucine-zipper-like motifs mediates MSL1 self-association in vitro and binding of the amino-terminal region of MSL1 to the MSL complex assembled on the male X chromosome.	Glycine	2-9	male-specific lethal 1	Drosophila melanogaster	79-83
15885796-7	2005	Furthermore, the excessive potentiation of [3H]d-ASP by GLY or GABA was already present in asymptomatic 30-40 day-old SOD1-G93A(+) mice.	Glycine	56-59	superoxide dismutase 1, soluble	Mus musculus	118-122
15976057-6	2005	The deduced amino acid sequence of chicken adiponectin contains 22 glycine-X-Y repeats (in which X and Y represent any amino acid) at the N-terminal end as found in the mammalian adiponectin.	Glycine	67-74	adiponectin, C1Q and collagen domain containing	Homo sapiens	179-190
16199870-7	2005	A glycine-rich motif between the basic and leucine-zipper-like motifs mediates MSL1 self-association in vitro and binding of the amino-terminal region of MSL1 to the MSL complex assembled on the male X chromosome.	Glycine	2-9	male-specific lethal 1	Drosophila melanogaster	154-158
16199870-7	2005	A glycine-rich motif between the basic and leucine-zipper-like motifs mediates MSL1 self-association in vitro and binding of the amino-terminal region of MSL1 to the MSL complex assembled on the male X chromosome.	Glycine	2-9	male-specific lethal 1	Drosophila melanogaster	79-82
16199870-8	2005	We propose that the basic region may mediate DNA binding and that the glycine-rich region may promote the association of MSL complexes to closely adjacent sites on the X chromosome.	Glycine	70-77	male-specific lethal 1	Drosophila melanogaster	121-124
15885796-8	2005	The releases of endogenous glutamate and GABA also were enhanced by GLY and the GLY-evoked release of endogenous glutamate, but not of endogenous GABA, was higher in SOD1-G93A(+) than in control animals.	Glycine	68-71	superoxide dismutase 1, soluble	Mus musculus	166-170
15885796-8	2005	The releases of endogenous glutamate and GABA also were enhanced by GLY and the GLY-evoked release of endogenous glutamate, but not of endogenous GABA, was higher in SOD1-G93A(+) than in control animals.	Glycine	80-83	superoxide dismutase 1, soluble	Mus musculus	166-170
15885796-5	2005	In SOD1(-)/G93A(-) or SOD1(+) mice GLY evoked [3H]d-ASP and [3H]GABA release, while GABA caused [3H]d-ASP, but not [3H]GLY, release.	Glycine	35-38	superoxide dismutase 1, soluble	Mus musculus	22-26
16166320-2	2005	Recent studies have established that an Arg (wild-type) to Gly mutation at amino acid 482 in ABCG2 alters substrate specificity.	Glycine	59-62	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	93-98
16112640-0	2005	Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.	Glycine	128-131	cytochrome P450 family 4 subfamily F member 12	Homo sapiens	80-87
16112640-7	2005	CYP4F enzymes with omega-hydroxylase activity contain a heme-binding Glu residue, whereas CYP4F8 (and CYP4F12) with omega2- and omega 3-hydroxylase activities has a Gly residue in this position of SRS-4.	Glycine	165-168	cytochrome P450 family 4 subfamily F member 12	Homo sapiens	102-109
16121195-5	2005	We, furthermore, present structures of ALAS(Rc) in complex with the substrates glycine or sCoA.	Glycine	79-86	5'-aminolevulinate synthase 1	Homo sapiens	39-43
16088915-4	2005	Molecular analysis of the COL2A1 gene revealed an A to G transition at nucleotide +79 of exon 41 that converted the codon for arginine at amino acid 792 to a codon for glycine (Arg792Gly).	Glycine	168-175	collagen type II alpha 1 chain	Homo sapiens	26-32
16162926-2	2005	They are heteromeric complexes of NR1 combined with NR2A-D and/or NR3A-B subunits that are activated by glutamate and glycine and whose activity is modulated by allosteric modulators.	Glycine	118-125	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	34-37
16292501-4	2005	Expression in HEK293 cells revealed that truncation of the N-terminus of GlyT1 results in significant inhibition of glycine uptake.	Glycine	116-123	solute carrier family 6 member 9	Homo sapiens	73-78
16141006-8	2005	By sequencing the CRYGS gene, a distinct 1619G-->T (AC068631) heterozygous missense mutation in exon 2 was identified, co-segregating with the disease phenotype in this family and resulting in a glycine (GGC) to valine residue (GTC) substitution in codon 18 (NP_060011).	Glycine	195-202	crystallin gamma S	Homo sapiens	18-23
15845872-0	2005	Glycine-extended gastrin stimulates cell proliferation and migration through a Rho- and ROCK-dependent pathway, not a Rac/Cdc42-dependent pathway.	Glycine	0-7	gastrin	Mus musculus	17-24
16021629-2	2005	Nef is found in the cytosol and also in association with cytoplasmic membranes, the latter, mediated in part by the myristoyl group attached to the N-terminal glycine.	Glycine	159-166	S100 calcium binding protein B	Homo sapiens	0-3
16077993-0	2005	Glycine- and proline-rich glycoprotein isolated from Solanum nigrum Linne activates caspase-3 through cytochrome c in HT-29 cells.	Glycine	0-7	caspase 3	Homo sapiens	84-93
16077993-0	2005	Glycine- and proline-rich glycoprotein isolated from Solanum nigrum Linne activates caspase-3 through cytochrome c in HT-29 cells.	Glycine	0-7	cytochrome c, somatic	Homo sapiens	102-114
16101730-11	2005	TNFalpha-mRNA was reduced after glycine- (5.2-fold), GdCl3- (19.7-fold), MP-treatment (39.5-fold) compared with controls.	Glycine	32-39	tumor necrosis factor	Rattus norvegicus	0-8
15970304-3	2005	Solitary wasp venoms caused significant voltage-dependent antagonism of nAChR responses to 10 microM ACh and NMDAR responses to 100 microM NMDA (+10 microM glycine) when co-applied at 1 microg/ml with the agonists.	Glycine	156-163	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	72-77
16101730-14	2005	Glycine appears to preserve cell viability and to TNFalpha/leukocyte dependent organ regeneration capacity, which is related to increase graft survival following liver transplantation.	Glycine	0-7	tumor necrosis factor	Rattus norvegicus	50-58
16135198-8	2005	Dhfr mutants and dhps Gly-437 were selected in treatment failure isolates.	Glycine	22-25	deoxyhypusine synthase	Homo sapiens	17-21
15998637-1	2005	Previous studies have suggested that thrombin interacts with integrins in endothelial cells through its RGD (Arg-187, Gly-188, Asp-189) sequence.	Glycine	118-121	coagulation factor II, thrombin	Homo sapiens	37-45
15970596-3	2005	Here we report that covalent modification of NR1-A652C or the analogous mutation in NR2A, -2B, -2C, or -2D by methanethiosulfonate ethylammonium (MT-SEA) occurs only in the presence of glutamate and glycine, and that modification potentiates recombinant NMDA receptor currents.	Glycine	199-206	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	45-48
15970596-3	2005	Here we report that covalent modification of NR1-A652C or the analogous mutation in NR2A, -2B, -2C, or -2D by methanethiosulfonate ethylammonium (MT-SEA) occurs only in the presence of glutamate and glycine, and that modification potentiates recombinant NMDA receptor currents.	Glycine	199-206	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	84-93
15994327-6	2005	Mutating an essential glycine residue in the Walker A motif abolished ABCG1-dependent cholesterol efflux and esterification and prevented localization of ABCG1 to the cell surface, indicating that the ATP binding domain in ABCG1 is essential for both lipid transport activity and protein trafficking.	Glycine	22-29	ATP binding cassette subfamily G member 1	Homo sapiens	70-75
15994327-6	2005	Mutating an essential glycine residue in the Walker A motif abolished ABCG1-dependent cholesterol efflux and esterification and prevented localization of ABCG1 to the cell surface, indicating that the ATP binding domain in ABCG1 is essential for both lipid transport activity and protein trafficking.	Glycine	22-29	ATP binding cassette subfamily G member 1	Homo sapiens	154-159
15994327-6	2005	Mutating an essential glycine residue in the Walker A motif abolished ABCG1-dependent cholesterol efflux and esterification and prevented localization of ABCG1 to the cell surface, indicating that the ATP binding domain in ABCG1 is essential for both lipid transport activity and protein trafficking.	Glycine	22-29	ATP binding cassette subfamily G member 1	Homo sapiens	154-159
16007099-4	2005	We show that p16(INK4a) suppresses the activity of c-Jun N-terminal kinases (JNKs) and that it binds to the glycine-rich loop of the N-terminal domain of JNK3.	Glycine	108-115	cyclin dependent kinase inhibitor 2A	Homo sapiens	13-16
15955813-2	2005	Herein we show that the Tudor domains of the spinal muscular atrophy gene product SMN, the splicing factor 30 kDa (SPF30), and the Tudor domain-containing 3 (TDRD3) proteins interacted with arginine-glycine-rich motifs in a methylarginine-dependent manner.	Glycine	199-206	tudor domain containing 3	Homo sapiens	131-156
15955813-2	2005	Herein we show that the Tudor domains of the spinal muscular atrophy gene product SMN, the splicing factor 30 kDa (SPF30), and the Tudor domain-containing 3 (TDRD3) proteins interacted with arginine-glycine-rich motifs in a methylarginine-dependent manner.	Glycine	199-206	tudor domain containing 3	Homo sapiens	158-163
16042403-18	2005	A dyad repeat sequence and the presence of glycine, serine, and hydrophobic residues in a repeated pattern in this peptide may be providing a favorable condition for the formation of a beta barrel-like structure in lipid bilayers.	Glycine	43-50	amyloid beta precursor protein	Homo sapiens	183-189
16075109-1	2005	Multi-stage mass spectrometry (MSn) on [(M + Ag - H)x + Ag]+ precursor ions (where M = an amino acid such as glycine or N,N-dimethylglycine) results in the formation of stable silver (Ag3+, Ag5+ and Ag7+) and silver hydride (Ag2H+, Ag4H+ and Ag6H+) cluster cations in the gas phase.	Glycine	109-116	moesin	Homo sapiens	31-34
16021449-5	2005	A direct antisuppressor effect of overproduced mRF1 is observed, since the MRF1 gene on a multicopy plasmid causes Gly(-) phenotypes of the leaky mit(-) point mutations in mtDNA.	Glycine	115-118	retroperitoneal fat pad weight 1	Mus musculus	47-51
16007099-4	2005	We show that p16(INK4a) suppresses the activity of c-Jun N-terminal kinases (JNKs) and that it binds to the glycine-rich loop of the N-terminal domain of JNK3.	Glycine	108-115	cyclin dependent kinase inhibitor 2A	Homo sapiens	17-22
15970667-3	2005	Recently, we have shown that MRE11 is arginine methylated in a C-terminal glycine-arginine rich (GAR) domain by protein arginine methyltransferase 1 (PRMT1).	Glycine	74-81	MRE11 homolog, double strand break repair nuclease	Homo sapiens	29-34
15890651-3	2005	Measurements of the individual rate constants defining the catalytic mechanism of substrate hydrolysis for wild-type thrombin and trypsin and their G193A and G193P mutants reveal that Gly-193 is required for optimal substrate binding and acylation.	Glycine	184-187	coagulation factor II, thrombin	Homo sapiens	117-125
15890651-4	2005	Crystal structures of the G193A and G193P mutants of thrombin bound to the active site inhibitor H-d-Phe-Pro-Arg-CH2Cl document the extent of perturbation induced by the replacement of Gly-193.	Glycine	185-188	coagulation factor II, thrombin	Homo sapiens	53-61
15949801-3	2005	Here, we have suggested the formation of an active site by structurally conserved residues in BH1 (glycine, arginine) and BH2 (tryptophan) domains of Bcl-2 family members, which also accounts for the functional effect of known mutations in BH1 (G145A, G145E) and BH2 (W188A) domains of Bcl-2.	Glycine	99-106	BCL2 apoptosis regulator	Homo sapiens	150-155
15949801-3	2005	Here, we have suggested the formation of an active site by structurally conserved residues in BH1 (glycine, arginine) and BH2 (tryptophan) domains of Bcl-2 family members, which also accounts for the functional effect of known mutations in BH1 (G145A, G145E) and BH2 (W188A) domains of Bcl-2.	Glycine	99-106	BCL2 apoptosis regulator	Homo sapiens	286-291
16212051-2	2005	A conformational study of glycine-monosubstituted analogues of neurokinins A and B].	Glycine	26-33	tachykinin precursor 1	Homo sapiens	63-82
16212051-3	2005	The conformational features of some glycine-monosubstituted analogues of neurokinins A and B were investigated by the method of theoretical conformational analysis.	Glycine	36-43	tachykinin precursor 1	Homo sapiens	73-92
16012719-6	2005	Growth of gastric cancer cell lines containing the gastrin/CCKB receptor was significantly enhanced by gastrin and glycine-extended gastrin.	Glycine	115-122	cholecystokinin B receptor	Homo sapiens	59-72
15996549-3	2005	Whereas ACPC and ACBC partially activate the NMDA receptor by 80% and 42%, respectively, their cocrystal structures of the NR1 ligand binding core show the same degree of domain closure as found in the complex with glycine, a full agonist, illustrating that the NR1 subunit provides a new paradigm for partial agonist action that is distinct from that of the evolutionarily related GluR2, AMPA-sensitive receptor.	Glycine	215-222	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	123-126
15996549-3	2005	Whereas ACPC and ACBC partially activate the NMDA receptor by 80% and 42%, respectively, their cocrystal structures of the NR1 ligand binding core show the same degree of domain closure as found in the complex with glycine, a full agonist, illustrating that the NR1 subunit provides a new paradigm for partial agonist action that is distinct from that of the evolutionarily related GluR2, AMPA-sensitive receptor.	Glycine	215-222	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	262-265
15741239-6	2005	L-Glycine or L-alanine mimicked the effect of glucose on basal leptin secretion but completely prevented stimulation by insulin.	Glycine	0-9	insulin	Homo sapiens	120-127
16018763-0	2005	Interleukin-1beta-induced prostaglandin E2 production by human gingival fibroblasts is upregulated by glycine.	Glycine	102-109	interleukin 1 beta	Homo sapiens	0-17
15895462-4	2005	Most COL2A1 mutations occur in the triple helical region of alpha 1(II) chains: the SED spectrum is mostly attributed to missense mutations that substitute bulky amino acids for glycine residues, STD-I to haploinsufficiency of truncation mutations, and KND to exon skipping due to splice-site mutations.	Glycine	178-185	collagen type II alpha 1 chain	Homo sapiens	5-11
16018763-5	2005	RESULTS: The PGE(2) production by IL-1beta-stimulated GFB was significantly upregulated by glycine.	Glycine	91-98	interleukin 1 beta	Homo sapiens	34-42
16018763-10	2005	The expression of COX-2 protein was slightly induced by glycine, more evidently by IL-1beta, and mostly enhanced by combined IL-1beta with glycine.	Glycine	56-63	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	18-23
16018763-10	2005	The expression of COX-2 protein was slightly induced by glycine, more evidently by IL-1beta, and mostly enhanced by combined IL-1beta with glycine.	Glycine	139-146	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	18-23
16018763-11	2005	CONCLUSION: Since PGE(2) is a potent stimulator of bone resorption, and production of PGE(2) and COX-2 protein is augmented by glycine, our results strongly suggest that glycine may be involved in the pathogenesis of periodontitis.	Glycine	127-134	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	97-102
16018763-11	2005	CONCLUSION: Since PGE(2) is a potent stimulator of bone resorption, and production of PGE(2) and COX-2 protein is augmented by glycine, our results strongly suggest that glycine may be involved in the pathogenesis of periodontitis.	Glycine	170-177	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	97-102
16018763-6	2005	The effect of glycine on IL- 1beta-induced cell proliferation and PGE(2) production was concentration- dependent, reached a peak at 3 mM, and declined slowly at higher doses.	Glycine	14-21	interleukin 1 beta	Homo sapiens	25-34
15882966-4	2005	Interestingly, mutant forms of Mgl-1 at the conserved glycine at position 450 and aspartic acid at position 453 in the most conserved WD-40 repeat motif were not able to complement, indicating that these amino acids are critical for regulating salt tolerance and temperature sensitivity in yeast.	Glycine	54-61	LLGL1 scribble cell polarity complex component	Mus musculus	31-36
16120573-5	2005	A new coding polymorphism was detected in PON1 gene, which gives rise to amino acid substitutions of arginine (R) for glycine (G) at codon 160, whereas L54M polymorphism, which is common in white population, was not detected in our Han population.	Glycine	118-125	paraoxonase 1	Homo sapiens	42-46
15599941-3	2005	The androgen receptor (AR) gene has polymorphic regions containing variable length glutamine and glycine repeats and these are believed to be associated with PC risk.	Glycine	97-104	androgen receptor	Homo sapiens	4-21
15870904-4	2005	Myristoyl-CoA:protein N-myristoyltransferase (NMT), which catalyzes the co-translational transfer of myristate from myristoyl-CoA to the amino-terminal glycine residue of selected polypeptides, is increased in the myocardium of ischemia-reperfusion rat model myocardium.	Glycine	152-159	N-myristoyltransferase 1	Homo sapiens	46-49
15880747-4	2005	Both deletion and duplication variants of the glycine-rich tract Gly5AlaGly5 inhibited E2A (E12/E47)-dependent transcription of CDKN1A to a similar degree as wild-type protein, indicating that the length of this glycine tract is not critical for efficient transcriptional repression.	Glycine	46-53	cyclin dependent kinase inhibitor 1A	Homo sapiens	128-134
15599941-3	2005	The androgen receptor (AR) gene has polymorphic regions containing variable length glutamine and glycine repeats and these are believed to be associated with PC risk.	Glycine	97-104	androgen receptor	Homo sapiens	23-25
15784623-0	2005	Transporter-associated currents in the gamma-aminobutyric acid transporter GAT-1 are conditionally impaired by mutations of a conserved glycine residue.	Glycine	136-143	solute carrier family 6 member 1	Homo sapiens	75-80
15784623-1	2005	To determine whether glycine residues play a role in the conformational changes during neurotransmitter transport, we have analyzed site-directed mutants of the gamma-aminobutyric acid (GABA) transporter GAT-1 in a domain containing three consecutive glycines conserved throughout the sodium- and chloride-dependent neurotransmitter transporter family.	Glycine	21-28	solute carrier family 6 member 1	Homo sapiens	204-209
15784623-7	2005	Thus, glycine 80 appears essential for conformational transitions in GAT-1.	Glycine	6-13	solute carrier family 6 member 1	Homo sapiens	69-74
15911376-0	2005	Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor.	Glycine	42-45	tachykinin precursor 1	Homo sapiens	72-83
15878328-6	2005	These results, together, indicate that QBRICK is an adhesive ligand of basement membrane distinctively recognized by cells in the embryonic skin and hair follicles through different types of integrins directed to the Arg-Gly-Asp motif.	Glycine	221-224	Fras1 related extracellular matrix protein 1	Mus musculus	39-45
15826655-9	2005	TDP43 from C.elegans lacks the glycine-rich domain found at the carboxy terminus of the other two homologues.	Glycine	31-38	TAR DNA binding protein	Homo sapiens	0-5
16184431-0	2005	Asp746 to glycine change may have a greater influence than Cys751 to serine change in accounting for ligand selectivity between EGFR and HER-2 at the ATP site.	Glycine	10-17	epidermal growth factor receptor	Homo sapiens	128-132
16184431-0	2005	Asp746 to glycine change may have a greater influence than Cys751 to serine change in accounting for ligand selectivity between EGFR and HER-2 at the ATP site.	Glycine	10-17	erb-b2 receptor tyrosine kinase 2	Homo sapiens	137-142
15650113-0	2005	Molecular determinants of glycine-independent desensitization of NR1/NR2A receptors.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	65-68
15857387-4	2005	The integrin ligand peptide Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) induced rapid (within 5 min) and robust increases in tyrosine phosphorylation of focal adhesion kinase, proline-rich tyrosine kinase 2 and Src family kinases.	Glycine	28-31	protein tyrosine kinase 2 beta	Rattus norvegicus	165-195
15857387-4	2005	The integrin ligand peptide Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) induced rapid (within 5 min) and robust increases in tyrosine phosphorylation of focal adhesion kinase, proline-rich tyrosine kinase 2 and Src family kinases.	Glycine	36-39	protein tyrosine kinase 2 beta	Rattus norvegicus	165-195
15650113-0	2005	Molecular determinants of glycine-independent desensitization of NR1/NR2A receptors.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	69-73
15650113-6	2005	On the other hand, several residues in the lurcher motif of either NR1 or NR2A are critical for the glycine-independent desensitization of NR1/NR2A receptors.	Glycine	100-107	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	67-70
15650113-2	2005	Previous studies have suggested that the molecular determinants for glycine-independent desensitization are located at two distinct domains of NR2A, i.e., the amino-terminal domain (ATD) and the pre-M1 domain.	Glycine	68-75	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	143-147
15650113-6	2005	On the other hand, several residues in the lurcher motif of either NR1 or NR2A are critical for the glycine-independent desensitization of NR1/NR2A receptors.	Glycine	100-107	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	74-78
15650113-6	2005	On the other hand, several residues in the lurcher motif of either NR1 or NR2A are critical for the glycine-independent desensitization of NR1/NR2A receptors.	Glycine	100-107	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	139-142
15763139-2	2005	The cocaine and tricyclic antidepressant-sensitive NET belongs to a family of sodium and chloride coupled transporters that include the monoamines dopamine and serotonin and the amino acids GABA and glycine.	Glycine	199-206	solute carrier family 6 member 2	Homo sapiens	51-54
15650113-6	2005	On the other hand, several residues in the lurcher motif of either NR1 or NR2A are critical for the glycine-independent desensitization of NR1/NR2A receptors.	Glycine	100-107	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	143-147
15769453-5	2005	RESULTS: (1) IL-1beta time-dependently increased the levels of two molecular forms of adrenomedullin, adrenomedullin-mature and adrenomedullin-glycine (P&lt;0.01).	Glycine	142-150	interleukin 1 beta	Rattus norvegicus	13-21
15635657-5	2005	The primary hydrophobic interactions with the micelle are from the leucine and phenylalanine residues (Leu-7, Phe-8, Leu-9, Phe-11, Leu-12) while the alanine and glycine residues (Ala-1, Gly-3, Gly-5, Ala-6, Gly-10, Gly-13, Ala-14, Ala-15, Gly-16, Gly-10, Ala-21) interact favorably with water molecules.	Glycine	187-190	beta-1,3-glucuronyltransferase 1	Homo sapiens	103-108
15805277-1	2005	MTI/G-Gly mice and hGAS mice, overexpressing glycine-extended gastrin (G-Gly) and progastrin, respectively, display colonic mucosa hyperplasia, hyperproliferation, and an increased susceptibility to intestinal neoplasia.	Glycine	45-52	gastrin	Mus musculus	62-69
15635657-5	2005	The primary hydrophobic interactions with the micelle are from the leucine and phenylalanine residues (Leu-7, Phe-8, Leu-9, Phe-11, Leu-12) while the alanine and glycine residues (Ala-1, Gly-3, Gly-5, Ala-6, Gly-10, Gly-13, Ala-14, Ala-15, Gly-16, Gly-10, Ala-21) interact favorably with water molecules.	Glycine	194-197	beta-1,3-glucuronyltransferase 1	Homo sapiens	103-108
15635657-5	2005	The primary hydrophobic interactions with the micelle are from the leucine and phenylalanine residues (Leu-7, Phe-8, Leu-9, Phe-11, Leu-12) while the alanine and glycine residues (Ala-1, Gly-3, Gly-5, Ala-6, Gly-10, Gly-13, Ala-14, Ala-15, Gly-16, Gly-10, Ala-21) interact favorably with water molecules.	Glycine	194-197	beta-1,3-glucuronyltransferase 1	Homo sapiens	103-108
15635657-5	2005	The primary hydrophobic interactions with the micelle are from the leucine and phenylalanine residues (Leu-7, Phe-8, Leu-9, Phe-11, Leu-12) while the alanine and glycine residues (Ala-1, Gly-3, Gly-5, Ala-6, Gly-10, Gly-13, Ala-14, Ala-15, Gly-16, Gly-10, Ala-21) interact favorably with water molecules.	Glycine	194-197	beta-1,3-glucuronyltransferase 1	Homo sapiens	103-108
15635657-5	2005	The primary hydrophobic interactions with the micelle are from the leucine and phenylalanine residues (Leu-7, Phe-8, Leu-9, Phe-11, Leu-12) while the alanine and glycine residues (Ala-1, Gly-3, Gly-5, Ala-6, Gly-10, Gly-13, Ala-14, Ala-15, Gly-16, Gly-10, Ala-21) interact favorably with water molecules.	Glycine	194-197	beta-1,3-glucuronyltransferase 1	Homo sapiens	103-108
15635657-5	2005	The primary hydrophobic interactions with the micelle are from the leucine and phenylalanine residues (Leu-7, Phe-8, Leu-9, Phe-11, Leu-12) while the alanine and glycine residues (Ala-1, Gly-3, Gly-5, Ala-6, Gly-10, Gly-13, Ala-14, Ala-15, Gly-16, Gly-10, Ala-21) interact favorably with water molecules.	Glycine	194-197	beta-1,3-glucuronyltransferase 1	Homo sapiens	103-108
15781195-9	2005	Adiponectin was significantly higher (p&lt;0.05) in subjects who simultaneously had the Ala/Ala (PPARgamma2)+Gly/Gly (IRS-1) genotype combination compared to subjects with the Pro/Pro+Gly/Gly and Pro/Ala+Gly/Gly genotype combinations.	Glycine	109-112	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
15781195-9	2005	Adiponectin was significantly higher (p&lt;0.05) in subjects who simultaneously had the Ala/Ala (PPARgamma2)+Gly/Gly (IRS-1) genotype combination compared to subjects with the Pro/Pro+Gly/Gly and Pro/Ala+Gly/Gly genotype combinations.	Glycine	113-116	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
15781195-9	2005	Adiponectin was significantly higher (p&lt;0.05) in subjects who simultaneously had the Ala/Ala (PPARgamma2)+Gly/Gly (IRS-1) genotype combination compared to subjects with the Pro/Pro+Gly/Gly and Pro/Ala+Gly/Gly genotype combinations.	Glycine	113-116	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
15811564-1	2005	A commonly occurring nucleotide polymorphism of the insulin-receptor substrate 2 (IRS-2) gene at amino acid 1057 from Glycine to Asparaginic acid (G1057D) was recently shown to be a determinant of insulin sensitivity in both glucose-tolerant individuals and those with type 2 diabetes.	Glycine	118-125	insulin	Homo sapiens	52-59
15781195-9	2005	Adiponectin was significantly higher (p&lt;0.05) in subjects who simultaneously had the Ala/Ala (PPARgamma2)+Gly/Gly (IRS-1) genotype combination compared to subjects with the Pro/Pro+Gly/Gly and Pro/Ala+Gly/Gly genotype combinations.	Glycine	113-116	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
15781195-9	2005	Adiponectin was significantly higher (p&lt;0.05) in subjects who simultaneously had the Ala/Ala (PPARgamma2)+Gly/Gly (IRS-1) genotype combination compared to subjects with the Pro/Pro+Gly/Gly and Pro/Ala+Gly/Gly genotype combinations.	Glycine	113-116	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
15781195-9	2005	Adiponectin was significantly higher (p&lt;0.05) in subjects who simultaneously had the Ala/Ala (PPARgamma2)+Gly/Gly (IRS-1) genotype combination compared to subjects with the Pro/Pro+Gly/Gly and Pro/Ala+Gly/Gly genotype combinations.	Glycine	113-116	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
15712334-1	2005	Nociceptin is a heptadecapeptide whose sequence is similar to that of Dynorphin A, sharing a message domain characterized by two glycines and two aromatic residues, and a highly basic C-terminal address domain but, in spite of these similarities, displays no opioid activity.	Glycine	129-137	prepronociceptin	Homo sapiens	0-10
15688094-3	2005	NMDA receptors in brain are regulated by glycine, acting via a strychnine-insensitive regulatory site, and by glycine (GlyT1) transporters that maintain low glycine levels in the immediate vicinity of the NMDA receptor complex.	Glycine	110-117	solute carrier family 6 member 9	Homo sapiens	119-124
15688094-3	2005	NMDA receptors in brain are regulated by glycine, acting via a strychnine-insensitive regulatory site, and by glycine (GlyT1) transporters that maintain low glycine levels in the immediate vicinity of the NMDA receptor complex.	Glycine	110-117	solute carrier family 6 member 9	Homo sapiens	119-124
15759151-0	2005	Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia.	Glycine	18-25	formyl peptide receptor 3	Mus musculus	63-66
15761697-4	2005	RESULTS: Polymorphisms in several genes known to interact with NMDA receptors are related to an altered risk for schizophrenia, and psychotic patients display changes in levels of mRNA encoding NMDA receptors, including the NR1 subunit on which Glycine(B) sites are located.	Glycine	245-252	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	224-227
15737434-1	2005	Transgenic mice carrying the human mutated SOD1 gene with a glycine/alanine substitution at codon 93 (G93A) are a widely used model for the fatal human disease amyotrophic lateral sclerosis (ALS).	Glycine	60-67	superoxide dismutase 1	Homo sapiens	43-47
15772895-12	2005	An alternate approach to partial glycine agonists is to inhibit the uptake carrier(s) for glycine (ie, GlyT-1 and GlyT-2), thereby potentiating the lifetime of synaptic glycine.	Glycine	90-97	solute carrier family 6 member 9	Homo sapiens	103-109
15680920-4	2005	The combined use of (1)H NMR, MD, and DSC has shown that: (i) at neutral pH, only Phe-Gly is able to prevent the thermally induced aggregation of cytochrome c; (ii) Phe-Gly interacts with Gly45 and Phe46 residues of the protein, either when the protein is in the folded or in the unfolded state; and (iii) the interaction of Phe-Gly with cytochrome c is sequence-dependent.	Glycine	86-89	cytochrome c, somatic	Homo sapiens	146-158
15680920-4	2005	The combined use of (1)H NMR, MD, and DSC has shown that: (i) at neutral pH, only Phe-Gly is able to prevent the thermally induced aggregation of cytochrome c; (ii) Phe-Gly interacts with Gly45 and Phe46 residues of the protein, either when the protein is in the folded or in the unfolded state; and (iii) the interaction of Phe-Gly with cytochrome c is sequence-dependent.	Glycine	86-89	cytochrome c, somatic	Homo sapiens	338-350
15680920-4	2005	The combined use of (1)H NMR, MD, and DSC has shown that: (i) at neutral pH, only Phe-Gly is able to prevent the thermally induced aggregation of cytochrome c; (ii) Phe-Gly interacts with Gly45 and Phe46 residues of the protein, either when the protein is in the folded or in the unfolded state; and (iii) the interaction of Phe-Gly with cytochrome c is sequence-dependent.	Glycine	169-172	cytochrome c, somatic	Homo sapiens	146-158
15680920-4	2005	The combined use of (1)H NMR, MD, and DSC has shown that: (i) at neutral pH, only Phe-Gly is able to prevent the thermally induced aggregation of cytochrome c; (ii) Phe-Gly interacts with Gly45 and Phe46 residues of the protein, either when the protein is in the folded or in the unfolded state; and (iii) the interaction of Phe-Gly with cytochrome c is sequence-dependent.	Glycine	169-172	cytochrome c, somatic	Homo sapiens	146-158
15660380-2	2005	Disease-causing mutations both in Nramp1 and Nramp2 occurring at the conserved two adjacent glycine residues located within the fourth transmembrane domain (TM4) suggest that TM4 may serve an important biological function.	Glycine	92-99	solute carrier family 11 member 2	Rattus norvegicus	45-51
15490133-2	2005	Glycine coactivates glutamate N-methyl-D-aspartate (NMDA) receptors by binding to a distinct recognition site on the NR1 subunit.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	117-120
15490133-3	2005	Purely excitatory glycine receptors composed of NR1 and NR3/NR4 NMDA receptor subunits have recently been described, raising the possibility of excitotoxic effects mediated by glycine alone.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	48-51
15743186-3	2005	On the basis of these findings, we combined in the N/OFQ-NH(2) template the chemical modifications Arg(14)-Lys(15) and (pF)Phe(4) that increase the agonist potency with those conferring partial agonist (Phe(1)Psi(CH(2)NH)Gly(2)) or pure antagonist (Nphe(1)) properties.	Glycine	221-224	prepronociceptin	Homo sapiens	51-56
15772895-12	2005	An alternate approach to partial glycine agonists is to inhibit the uptake carrier(s) for glycine (ie, GlyT-1 and GlyT-2), thereby potentiating the lifetime of synaptic glycine.	Glycine	33-40	solute carrier family 6 member 9	Homo sapiens	103-109
15772895-12	2005	An alternate approach to partial glycine agonists is to inhibit the uptake carrier(s) for glycine (ie, GlyT-1 and GlyT-2), thereby potentiating the lifetime of synaptic glycine.	Glycine	90-97	solute carrier family 6 member 9	Homo sapiens	103-109
15572392-14	2005	DRB1*1104 and DRB1*1101 differ by a single amino acid at position 86, where the former has valine and the latter glycine.	Glycine	113-120	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-4
15598685-7	2005	The proposita had a missense mutation (GTG to GGG) in codon 458 of the TRbeta gene, resulting in the replacement of the normal valine with glycine (V458G).	Glycine	139-146	T cell receptor beta locus	Homo sapiens	71-77
15760549-0	2005	[The effect of glycine on CD14 and NF-kappa B in Kupffer cells from rat liver grafts after ischemia-reperfusion injury].	Glycine	15-22	CD14 molecule	Rattus norvegicus	26-30
15760549-1	2005	OBJECTIVE: To investigate the effect of glycine on CD14 and NF-kappa B in Kupffer cells from rat liver grafts after ischemia-reperfusion injury (IRI).	Glycine	40-47	CD14 molecule	Rattus norvegicus	51-55
15760549-6	2005	(2) The CD14 mRNA expression level (F = 7.64), NF-kappa B binding activity (F = 11.47), TNF alpha and IL-1 production (F = 14.08 and 9.56 respectively) in the glycine group were significantly lower than those in the other two groups.	Glycine	159-166	CD14 molecule	Rattus norvegicus	8-12
15760549-6	2005	(2) The CD14 mRNA expression level (F = 7.64), NF-kappa B binding activity (F = 11.47), TNF alpha and IL-1 production (F = 14.08 and 9.56 respectively) in the glycine group were significantly lower than those in the other two groups.	Glycine	159-166	tumor necrosis factor	Rattus norvegicus	88-97
15760549-7	2005	CONCLUSION: Glycine could efficiently protect rat liver grafts from ischemia-reperfusion injury by repressing the expression of CD14 and NF-kappa B binding activity in Kupffer cells and inhibiting the productions of TNF alpha and IL-1.	Glycine	12-19	CD14 molecule	Rattus norvegicus	128-132
15760549-7	2005	CONCLUSION: Glycine could efficiently protect rat liver grafts from ischemia-reperfusion injury by repressing the expression of CD14 and NF-kappa B binding activity in Kupffer cells and inhibiting the productions of TNF alpha and IL-1.	Glycine	12-19	tumor necrosis factor	Rattus norvegicus	216-225
15473865-4	2005	Known in vitro substrates for PRMT3 include GST-GAR (a glutathione S-transferase fusion protein containing the glycine- and arginine-rich N-terminal region of fibrillarin), Sam68 (Src-associated substrate during mitosis 68 kDa) and PABP-N1 [poly(A)-binding protein-N1; PABP2].	Glycine	111-118	protein arginine methyltransferase 3	Homo sapiens	30-35
15473865-10	2005	Deletion analysis of the rpS2 amino acid sequence identified a N-terminal Arg-Gly repeat as the methylation site.	Glycine	78-81	ribosomal protein S2	Homo sapiens	25-29
15883743-10	2005	RESULTS: Glycine added to the culture medium increased both ATP and glycogen contents of PCLS from LPS-treated rats, reduced the production of TNF-alpha and NOx whereas PGE(2) secretion by PCLS increased.	Glycine	9-16	tumor necrosis factor	Rattus norvegicus	143-152
15809332-5	2005	Each protein contained a pair of active site motifs (Asp/Thr or Ser/Gly), which is a common characteristic of aspartic proteases including BACE1.	Glycine	68-71	beta-secretase 1	Homo sapiens	139-144
15528201-2	2005	To characterize the voltage sensor movement associated with hERG activation and inactivation, we performed an Ala scan of the 32 amino acids (Gly(514)-Tyr(545)) that comprise the S4 domain and the flanking S3-S4 and S4-S5 linkers.	Glycine	142-145	ETS transcription factor ERG	Homo sapiens	60-64
15770064-11	2005	However, only (Pro-Pro-Gly)5 and (Pro-Pro-Gly)10 induced expression of PI3-K and phosphorylation of p38 MAP kinase, suggesting a potential mechanism underlying reduced chemotactic activity of Hyp-containing peptides.	Glycine	22-26	mitogen-activated protein kinase 14	Homo sapiens	100-114
15572392-14	2005	DRB1*1104 and DRB1*1101 differ by a single amino acid at position 86, where the former has valine and the latter glycine.	Glycine	113-120	major histocompatibility complex, class II, DR beta 1	Homo sapiens	14-18
15572035-1	2005	We screened for genes specifically expressed in the mesenchymes of developing hair follicles using representational differential analysis; one gene identified was MAEG, which encodes a protein consisting of five EGF-like repeats, a linker segment containing a cell-adhesive Arg-Gly-Asp (RGD) motif, and a MAM domain.	Glycine	278-281	EGF-like-domain, multiple 6	Mus musculus	163-167
15671159-4	2005	The atomic structure of AQP1 and amino acid sequence alignments of the mammalian aquaporins reveal two well conserved glycine residues: Gly-57 in transmembrane helix (TM) 2 and Gly-173 in TM5 reside at the contact point where the two helices cross in human AQP1.	Glycine	118-125	aquaporin 1 (Colton blood group)	Homo sapiens	24-28
15671159-4	2005	The atomic structure of AQP1 and amino acid sequence alignments of the mammalian aquaporins reveal two well conserved glycine residues: Gly-57 in transmembrane helix (TM) 2 and Gly-173 in TM5 reside at the contact point where the two helices cross in human AQP1.	Glycine	136-139	aquaporin 1 (Colton blood group)	Homo sapiens	24-28
15671159-4	2005	The atomic structure of AQP1 and amino acid sequence alignments of the mammalian aquaporins reveal two well conserved glycine residues: Gly-57 in transmembrane helix (TM) 2 and Gly-173 in TM5 reside at the contact point where the two helices cross in human AQP1.	Glycine	177-180	aquaporin 1 (Colton blood group)	Homo sapiens	24-28
15671159-7	2005	Replacement of the glycine at this site in AQP0, AQP1, and AQP2 blocked expression of the mutants at the oocyte plasma membrane.	Glycine	19-26	major intrinsic protein of lens fiber	Homo sapiens	43-47
15671159-7	2005	Replacement of the glycine at this site in AQP0, AQP1, and AQP2 blocked expression of the mutants at the oocyte plasma membrane.	Glycine	19-26	aquaporin 1 (Colton blood group)	Homo sapiens	49-53
15591042-6	2005	Unique among the residues in this region, Pro823, which is highly conserved in family 3 of the G protein-coupled receptors, when mutated to either alanine or glycine, despite good expression severely impaired CaR activation by Ca2+.	Glycine	158-165	calcium sensing receptor	Homo sapiens	209-212
15699368-9	2005	The 828C-->G mutation causes a substitution of a glycine for an alanine residue in the HS1-BP3 protein.	Glycine	49-56	HCLS1 binding protein 3	Homo sapiens	87-94
15671219-1	2005	Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that exists as cytosolic and mitochondrial isozymes that catalyze the reversible interconversion of serine and tetrahydrofolate (THF) to glycine and 5,10-methyleneTHF.	Glycine	224-231	serine hydroxymethyltransferase 1	Rattus norvegicus	0-31
15671219-1	2005	Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that exists as cytosolic and mitochondrial isozymes that catalyze the reversible interconversion of serine and tetrahydrofolate (THF) to glycine and 5,10-methyleneTHF.	Glycine	224-231	serine hydroxymethyltransferase 1	Rattus norvegicus	33-37
15671219-8	2005	Hepatic glycine concentration was inversely related to vitamin B-6 intake (P &lt; 0.05), which suggests a functional effect of altered SHMT activity.	Glycine	8-15	serine hydroxymethyltransferase 1	Rattus norvegicus	135-139
15389799-0	2005	Effect of GGC (glycine) repeat length polymorphism in the human androgen receptor on androgen action.	Glycine	15-22	androgen receptor	Homo sapiens	64-81
15389799-1	2005	BACKGROUND: The human androgen receptor (AR) contains glutamine (CAG) and glycine (GGC) repeat length polymorphisms.	Glycine	74-81	androgen receptor	Homo sapiens	22-39
15389799-1	2005	BACKGROUND: The human androgen receptor (AR) contains glutamine (CAG) and glycine (GGC) repeat length polymorphisms.	Glycine	74-81	androgen receptor	Homo sapiens	41-43
15389799-6	2005	However, AR protein levels (normalized for transfection efficiency) were inversely affected by glycine repeat length (P &lt; 0.001; r = -0.9; e.g., GGC13 yielded 2.7 times more AR protein than did GGC17).	Glycine	95-102	androgen receptor	Homo sapiens	9-11
15389799-7	2005	Therefore, the net amount of AR activity per cell would be higher in cells expressing AR with a short glycine repeat.	Glycine	102-109	androgen receptor	Homo sapiens	29-31
15389799-7	2005	Therefore, the net amount of AR activity per cell would be higher in cells expressing AR with a short glycine repeat.	Glycine	102-109	androgen receptor	Homo sapiens	86-88
15507442-2	2005	The recently solved crystal structures of the AID-Ca(V)beta complex in Ca(V)1.1/1.2 have revealed that this interaction occurs through a set of six mostly invariant residues Glu/Asp(6), Leu(7), Gly(9), Tyr(10), Trp(13), and Ile(14) (where the superscript refers to the position of the residue starting with the QQ signature doublet) distributed among three alpha-helical turns in the proximal section of the I-II linker.	Glycine	194-197	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	71-83
15684035-4	2005	Using recombinant proteins, we found uPAR directly binds alpha5beta1 and rather than blocking, renders fibronectin (Fn) binding by alpha5beta1 Arg-Gly-Asp (RGD) resistant.	Glycine	147-150	fibronectin 1	Homo sapiens	116-118
15641147-21	2005	However, TNF-alpha significantly decreased after pretreatment with glycine, PD98059 and SB212850.	Glycine	67-74	tumor necrosis factor	Rattus norvegicus	9-18
15673683-4	2005	The ocr-2(yz5) mutation results in a glycine-to-glutamate substitution (G36E) within the N-terminal region.	Glycine	37-44	Ion_trans domain-containing protein	Caenorhabditis elegans	4-9
15565302-7	2005	In the two missense mutations, the strong basic residue arginine was substituted by serine or glycine in highly conserved components of the putative transmembrane domain of PTCH, and these mutations may therefore affect the conformation and function of the PTCH protein.	Glycine	94-101	patched 1	Homo sapiens	173-177
16508120-2	2005	The Kelch/DGR (double-glycine repeat) domain of Keap1 associates with Nrf2 as well as with actin filaments.	Glycine	22-29	nuclear factor, erythroid derived 2, like 2	Mus musculus	70-74
15565302-7	2005	In the two missense mutations, the strong basic residue arginine was substituted by serine or glycine in highly conserved components of the putative transmembrane domain of PTCH, and these mutations may therefore affect the conformation and function of the PTCH protein.	Glycine	94-101	patched 1	Homo sapiens	257-261
15886745-9	2005	Regarding the study of angiogenesis the following have been described: a. antibodies targeting VEGF, labeled with radionuclides emitting beta- and/or gamma-radiation, which can be applied for the diagnosis and possibly, for the treatment of cancer, b. peptide derivatives which contain the amino-acid sequence RGD (Arg-Gly-Asp) and compete for the alpha(nu)beta(3) integrins, with the proteins of the stroma.	Glycine	319-322	vascular endothelial growth factor A	Homo sapiens	95-99
15773232-4	2005	We found that compared with the baseline systolic BP (SBP) of subjects with one ACE I allele and one alpha-adducin Trp allele, the baseline SBP of those with ACE DD and alpha-adducin Gly/Gly genotypes was significantly higher [Crude: beta(SE) = 7.83(3.09), p = .01; Adjusted: beta(SE) = 5.83(2.83), p = .04].	Glycine	183-186	adducin 1	Homo sapiens	169-182
15773232-4	2005	We found that compared with the baseline systolic BP (SBP) of subjects with one ACE I allele and one alpha-adducin Trp allele, the baseline SBP of those with ACE DD and alpha-adducin Gly/Gly genotypes was significantly higher [Crude: beta(SE) = 7.83(3.09), p = .01; Adjusted: beta(SE) = 5.83(2.83), p = .04].	Glycine	187-190	adducin 1	Homo sapiens	169-182
24790307-4	2005	Molecular analysis demonstrated that he was hemizygous for a G to C transversion in exon 2 of the AVPR2 gene which resulted in a glycine to arginine substitution (G107R) at the 107th codon of the first extracellular loop.	Glycine	129-136	arginine vasopressin receptor 2	Homo sapiens	98-103
15619635-5	2005	Whereas nonpolar and some aliphatic residues were permissive, charged residues and glycine compromised the post-translational folding and stability of NBD2 and CFTR.	Glycine	83-90	CF transmembrane conductance regulator	Homo sapiens	160-164
15623827-5	2005	Exposure to 1-5 mmol/L H(2)O(2) for 24 h caused a dose-dependent decrease in Gly-Sar transport, which was associated with decreased PepT1 transport velocity (V(max)).	Glycine	77-80	solute carrier family 15 member 1	Homo sapiens	132-137
15597199-5	2004	A short molecular dynamics simulation of the glycine-bound form of wild-type and double-mutated (D481N; K483Q) NR1 subunit structure shows considerable RMSD at the hinge region of S1S2 segment, where pore forming transmembrane helices are located in the native receptor.	Glycine	45-52	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	111-114
15864123-14	2005	This preliminary study points to the possibility that patients homozygous for glycine at the 990 position in exon 7 of the CaSR may be more sensitive to the calcimimetic drug cinacalcet compared to those who are homozygous for arginine at that location.	Glycine	78-85	calcium sensing receptor	Homo sapiens	123-127
15485890-2	2004	The binding of the abundant extracellular matrix ligand fibronectin to integrins alpha(5)beta(1) and alpha(v)beta(3) is known to depend upon the Arg-Gly-Asp (RGD) motif on the tenth fibronectin FIII domain.	Glycine	149-152	fibronectin 1	Homo sapiens	56-67
15485890-2	2004	The binding of the abundant extracellular matrix ligand fibronectin to integrins alpha(5)beta(1) and alpha(v)beta(3) is known to depend upon the Arg-Gly-Asp (RGD) motif on the tenth fibronectin FIII domain.	Glycine	149-152	fibronectin 1	Homo sapiens	182-193
15517563-10	2004	CONCLUSIONS: Glycine mutations at position 482 have a significant impact on ABCG2 function by modifying its substrate specificity and its influx/efflux rates.	Glycine	13-20	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	76-81
15282265-8	2004	Moreover, hPEPT2*1 and *2 differed in their pH sensitivity for H+/Gly-Sar transport.	Glycine	66-69	solute carrier family 15 member 2	Homo sapiens	10-16
15548680-0	2004	Overexpression of glycine-extended gastrin inhibits parietal cell loss and atrophy in the mouse stomach.	Glycine	18-25	gastrin	Mus musculus	35-42
15364907-7	2004	Our data reveal a key structural role of Glu(27), providing a molecular basis for the reported loss of enzymatic activity displayed by the equivalent Glu --&gt; Gly mutation in KAT-I of spontaneously hypertensive rats.	Glycine	161-164	kynurenine aminotransferase 1	Homo sapiens	177-182
15548680-1	2004	Recently we have reported synergistic effects between glycine-extended gastrin (G-gly) and amidated gastrin-17 on acid secretion in short-term infusion studies.	Glycine	54-61	gastrin	Mus musculus	71-78
15491626-5	2004	Previous studies reveal that a single face of the glycophorin A monomer contains a specific glycine-containing motif (GxxxG) that is thought to be a driving force for the association of transmembrane helices.	Glycine	92-99	glycophorin A (MNS blood group)	Homo sapiens	50-63
15242825-5	2004	Therefore, we hypothesize that dietary protein may impact the functional response to glycine infusion in both untreated rats and rats pretreated with angiotensin-converting enzyme (ACE) inhibitor and, furthermore, that renal NMDA receptors may be involved in the glycine response.	Glycine	85-92	angiotensin I converting enzyme	Rattus norvegicus	150-179
15525469-1	2004	AIM: To construct another growth hormone releasing hormone (GHRH) analog, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys peptide and to compare its activity with that of Pro-Pro-hGHRH(1-44)OH peptide.	Glycine	94-97	growth hormone releasing hormone	Homo sapiens	26-58
15525469-1	2004	AIM: To construct another growth hormone releasing hormone (GHRH) analog, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys peptide and to compare its activity with that of Pro-Pro-hGHRH(1-44)OH peptide.	Glycine	94-97	growth hormone releasing hormone	Homo sapiens	60-64
15525469-1	2004	AIM: To construct another growth hormone releasing hormone (GHRH) analog, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys peptide and to compare its activity with that of Pro-Pro-hGHRH(1-44)OH peptide.	Glycine	94-97	growth hormone releasing hormone	Homo sapiens	82-87
15525469-1	2004	AIM: To construct another growth hormone releasing hormone (GHRH) analog, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys peptide and to compare its activity with that of Pro-Pro-hGHRH(1-44)OH peptide.	Glycine	98-101	growth hormone releasing hormone	Homo sapiens	26-58
15525469-1	2004	AIM: To construct another growth hormone releasing hormone (GHRH) analog, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys peptide and to compare its activity with that of Pro-Pro-hGHRH(1-44)OH peptide.	Glycine	98-101	growth hormone releasing hormone	Homo sapiens	60-64
15525469-1	2004	AIM: To construct another growth hormone releasing hormone (GHRH) analog, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys peptide and to compare its activity with that of Pro-Pro-hGHRH(1-44)OH peptide.	Glycine	98-101	growth hormone releasing hormone	Homo sapiens	82-87
15525469-2	2004	METHODS: The pro-pro-hGHRH(1-44)-gly-gly-cys DNA fragment was synthesized by polymerase chain reaction.	Glycine	33-36	growth hormone releasing hormone	Homo sapiens	21-26
15525469-2	2004	METHODS: The pro-pro-hGHRH(1-44)-gly-gly-cys DNA fragment was synthesized by polymerase chain reaction.	Glycine	37-40	growth hormone releasing hormone	Homo sapiens	21-26
15525469-4	2004	The Pro-Pro-hGHRH (1-44)-Gly-Gly-Cys peptide was purified to homogeneity by cell disruption, washing, ethanol precipitation, acid hydrolysis, and SP-Sephadex C-25 and Sephadex G-25 column chromatography.	Glycine	25-28	growth hormone releasing hormone	Homo sapiens	12-17
15240345-10	2004	Mitochondria, which produce glyoxylate from hydroxyproline metabolism, contained both alanine:glyoxylate aminotransferase (AGT)2 and glyoxylate reductase activities, which can convert glyoxylate to glycine and glycolate, respectively.	Glycine	198-205	alanine--glyoxylate aminotransferase 2	Homo sapiens	123-128
15240345-10	2004	Mitochondria, which produce glyoxylate from hydroxyproline metabolism, contained both alanine:glyoxylate aminotransferase (AGT)2 and glyoxylate reductase activities, which can convert glyoxylate to glycine and glycolate, respectively.	Glycine	198-205	glyoxylate and hydroxypyruvate reductase	Homo sapiens	133-153
15521010-11	2004	Cells overexpressing hPepT1 showed increased Gly-Sar and MDP uptake, whereas decreased uptake was observed after hPepT1 siRNA-inhibition.	Glycine	45-48	solute carrier family 15 member 1	Homo sapiens	21-27
15315956-7	2004	These results also suggest that a left-handed Gly heptad repeat motif can drive membrane helix association, but the affinity is likely to be less strong than the previously reported right-handed motif described for glycophorin A.	Glycine	46-49	glycophorin A (MNS blood group)	Homo sapiens	215-228
15655705-2	2004	GLP-1 is found in two active forms, amidated GLP-1 (7-36) amide and glycine-extended GLP-1 (7-37), while GIP exists as a single 42 amino acid peptide.	Glycine	68-75	glucagon	Homo sapiens	0-5
15322097-5	2004	Mutation of the leucine or glycine (LSGGQ) in TAP1 fully abolished peptide transport.	Glycine	27-34	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	46-50
15240826-5	2004	Application of D-amino acid oxidase, an enzyme that degrades D-serine, markedly inhibited neuronal damage by NMDA and simulated ischemia, which was reversed by addition of excess D-serine or glycine.	Glycine	191-198	D-amino-acid oxidase	Rattus norvegicus	15-35
15278097-7	2004	Glycine (GLYT1) and small neutral amino-acid (SNAT) transporters, which regulate glycine levels, represent additional targets for drug development, and may represent a site of action of clozapine.	Glycine	0-7	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	9-14
15278097-7	2004	Glycine (GLYT1) and small neutral amino-acid (SNAT) transporters, which regulate glycine levels, represent additional targets for drug development, and may represent a site of action of clozapine.	Glycine	81-88	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	9-14
15340850-6	2004	Using the kinetic parameters of PEPT1 and the basolateral peptide transporter, a computational model of Gly-Sar transport in Caco-2 cells was constructed.	Glycine	104-107	solute carrier family 15 member 1	Homo sapiens	32-37
15485556-1	2004	Glycine-9 and leucine-10 of substance P (SP) are critical for (NK)-1 receptor recognition and agonist activity.	Glycine	0-7	tachykinin precursor 1	Homo sapiens	28-39
15485557-2	2004	A Gly scan was performed where each amino acid in Ang II was substituted one-by-one with glycine.	Glycine	2-5	angiotensinogen	Rattus norvegicus	50-56
15485557-2	2004	A Gly scan was performed where each amino acid in Ang II was substituted one-by-one with glycine.	Glycine	89-96	angiotensinogen	Rattus norvegicus	50-56
15374578-3	2004	Since cerebral glycine concentration in the vicinity of NMDA receptors is thought to be controlled by the glia expressed glycine transporter type 1 (GlyT1), the effects of several typical and atypical antipsychotics on glycine uptake were examined in human placenta choriocarcinoma (JAR) cells expressing human GlyT1a.	Glycine	15-22	solute carrier family 6 member 9	Homo sapiens	121-147
15374578-3	2004	Since cerebral glycine concentration in the vicinity of NMDA receptors is thought to be controlled by the glia expressed glycine transporter type 1 (GlyT1), the effects of several typical and atypical antipsychotics on glycine uptake were examined in human placenta choriocarcinoma (JAR) cells expressing human GlyT1a.	Glycine	15-22	solute carrier family 6 member 9	Homo sapiens	149-154
15378162-10	2004	Further GEE analyses of the three genes combined showed that the association between serum uric acid and the ACE polymorphism was confined to carriers of the alpha-adducin Gly and/or aldosterone synthase C alleles.	Glycine	172-175	angiotensin I converting enzyme	Homo sapiens	109-112
15359279-2	2004	Remarkably, splice variants that differ only by the insertion of a single glycine residue in the beta1/beta2 loop exhibit dual specificity for PtdIns(3,4,5)P(3) and PtdIns(4,5)P(2).	Glycine	74-81	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	97-102
15359279-6	2004	Conversely, a small increase rather than decrease in affinity for PtdIns(4,5)P(2) is explained by a novel binding mode, in which the glycine insertion alleviates unfavorable interactions with the beta1/beta2 loop.	Glycine	133-140	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	196-207
15252017-0	2004	The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.	Glycine	26-34	ATP binding cassette subfamily C member 1	Homo sapiens	79-83
15252017-3	2004	In the present study, the conserved glycines in the fourth position of the LSGGQ motifs of human MRP1 were substituted for aspartic acids (G771D and G1433D), the mutants were expressed in Sf9 insect cells, and the nucleotideas well as the transported substrate-protein interactions were studied.	Glycine	36-44	ATP binding cassette subfamily C member 1	Homo sapiens	97-101
15334060-7	2004	DAL-1/4.1B was determined not to be a substrate for PRMT3-mediated methylation but its presence inhibits the in vitro methylation of a glycine-rich and arginine-rich methyl-accepting protein, GST (glutathione-S-transferase-GAR (glycine- and arginine-rich), which contains 14 "RGG" consensus methylation sites.	Glycine	135-142	erythrocyte membrane protein band 4.1 like 3	Homo sapiens	0-10
15334060-7	2004	DAL-1/4.1B was determined not to be a substrate for PRMT3-mediated methylation but its presence inhibits the in vitro methylation of a glycine-rich and arginine-rich methyl-accepting protein, GST (glutathione-S-transferase-GAR (glycine- and arginine-rich), which contains 14 "RGG" consensus methylation sites.	Glycine	228-235	erythrocyte membrane protein band 4.1 like 3	Homo sapiens	0-10
15198928-4	2004	Quiescent HMC were exposed to 200 microg/ml bovine serum albumin (BSA) or glycated BSA (Gly-BSA) for 12-72 h. At 24 h, Gly-BSA stimulated TGF-beta1 and PAI-1 mRNA expression in HMC to 1.8 and 3.2 times that in the BSA-treated control cells.	Glycine	119-122	albumin	Homo sapiens	51-64
15198928-4	2004	Quiescent HMC were exposed to 200 microg/ml bovine serum albumin (BSA) or glycated BSA (Gly-BSA) for 12-72 h. At 24 h, Gly-BSA stimulated TGF-beta1 and PAI-1 mRNA expression in HMC to 1.8 and 3.2 times that in the BSA-treated control cells.	Glycine	119-122	transforming growth factor beta 1	Homo sapiens	138-147
15378162-10	2004	Further GEE analyses of the three genes combined showed that the association between serum uric acid and the ACE polymorphism was confined to carriers of the alpha-adducin Gly and/or aldosterone synthase C alleles.	Glycine	172-175	adducin 1	Homo sapiens	158-171
15378162-12	2004	Among 114 informative offspring carrying the alpha-adducin Gly allele serum uric acid was significantly and positively associated with the transmission of the ACE D allele (beta=20.7 micromol/l).	Glycine	59-62	adducin 1	Homo sapiens	45-58
15378162-12	2004	Among 114 informative offspring carrying the alpha-adducin Gly allele serum uric acid was significantly and positively associated with the transmission of the ACE D allele (beta=20.7 micromol/l).	Glycine	59-62	angiotensin I converting enzyme	Homo sapiens	159-162
15237104-7	2004	Positive control (PC) mutations at Asp-10 and Gly-123 of TraR did not affect DNA binding but greatly decreased the TraR-RpoAAt interaction.	Glycine	46-49	transcriptional regulator TraR	Agrobacterium tumefaciens	57-61
15237104-9	2004	When co-expressed, mutants of TraR with substitutions at Asp-10 complementing mutants with substitutions at Gly-123 for gene activation in an allele-specific manner.	Glycine	108-111	transcriptional regulator TraR	Agrobacterium tumefaciens	30-34
15355355-11	2004	Critical amino acids in EF-hand 1 of GCAP-1 are cysteine at position 29 and proline at position 30, as changing these to glycine was sufficient to cause loss of target activation without a loss of Ca2+-induced conformational changes.	Glycine	121-128	guanylate cyclase activator 1A	Homo sapiens	37-43
15377425-14	2004	CONCLUSION: Glycine and MP reduce organ injury and mortality caused by hemorrhagic shock by preventing increase of intracellular calcium levels in Kupffer cell, suppressing Kupffer cell activation, decreasing the production of TNF-alpha by Kupffer cells, and blocking systemic inflammatory responses.	Glycine	12-19	tumor necrosis factor	Rattus norvegicus	227-236
15329888-8	2004	VGLUT3 cells were not immunoreactive for amacrine cell markers gamma-aminobutyric acid, choline acetyltransferase, calretinin, or tyrosine hydroxylase, although they immunostain for glycine.	Glycine	182-189	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	Mus musculus	0-6
15329889-7	2004	The processes of this cell type were presynaptic to GlyR alpha2 puncta, suggesting that vGluT3 amacrine cells release glycine.	Glycine	118-125	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	Mus musculus	88-94
15325260-0	2004	The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice.	Glycine	4-11	tumor necrosis factor	Rattus norvegicus	84-93
15325260-2	2004	It is known that glycine prevents LPS-induced production of TNF-alpha in isolated Kupffer cells.	Glycine	17-24	tumor necrosis factor	Mus musculus	60-69
15307182-2	2004	Immune recognition of EBNA1 by CD8+ T cells is prevented by an internal glycine-alanine repeat (GAr) which blocks proteasomal degradation.	Glycine	72-79	EBNA-1	Human gammaherpesvirus 4	22-27
15199058-7	2004	Mutation to the rodent homologue glycine or glutamate resulted in a significant reduction in binding compared with native IgE, whereas conservative substitution with arginine effected a small, but statistically significant, enhancement of CD23 binding.	Glycine	33-40	immunoglobulin heavy constant epsilon	Homo sapiens	122-125
15359084-6	2004	Recent site-directed mutagenesis has revealed that these inhibitors possess some molecular determinants (Phe-213, Val-227, Tyr-228, Gly-833, and Asn-839) for interaction with NCX1.	Glycine	132-135	solute carrier family 8 member A1	Homo sapiens	175-179
15169788-11	2004	These data demonstrate that the conformational changes accompanying channel gating increase accessibility to amino acids critical for drug action in TM1, TM2, and TM3, which may provide a mechanism by which alcohols and anesthetics can act on glycine (and likely other) receptors.	Glycine	243-250	tropomyosin 3 L homeolog	Xenopus laevis	163-166
15208269-6	2004	Consistent with this finding, HNPs bound to and promoted the binding of fibronectin to alpha5beta1 integrin in arginine-glycine-aspartic acid (RGD)-independent manner.	Glycine	120-127	fibronectin 1	Homo sapiens	72-83
15072962-6	2004	In addition, the fold change for both IL-8 and IL-6 was markedly higher (P &lt; 0.05) in Lo Gly compared with Con.	Glycine	92-95	C-X-C motif chemokine ligand 8	Homo sapiens	38-42
15072962-6	2004	In addition, the fold change for both IL-8 and IL-6 was markedly higher (P &lt; 0.05) in Lo Gly compared with Con.	Glycine	92-95	interleukin 6	Homo sapiens	47-51
15226418-4	2004	Importantly, we identified a fusion peptide between the N-terminal methionine of ERK3 and the C-terminal glycine of ubiquitin in vivo by tandem mass spectrometry analysis.	Glycine	105-112	mitogen-activated protein kinase 6	Homo sapiens	81-85
15245898-7	2004	In this first approach, cathepsin L was used to cleave a linker sequence including a cathepsin L site: afrsaaq, thereby releasing the tri-peptide Arg-Gly-Asp (RGD) from the PNA anchor.	Glycine	150-153	cathepsin L	Homo sapiens	24-35
15245898-7	2004	In this first approach, cathepsin L was used to cleave a linker sequence including a cathepsin L site: afrsaaq, thereby releasing the tri-peptide Arg-Gly-Asp (RGD) from the PNA anchor.	Glycine	150-153	cathepsin L	Homo sapiens	85-96
15004000-7	2004	treating cells cultured on fibronectin with soluble Arg-Gly-Asp-Ser (RGDS) peptide to specifically block integrin-fibronectin interactions.	Glycine	56-59	fibronectin 1	Homo sapiens	114-125
15469714-7	2004	When Cu,Zn-SOD that had been exposed to catecholamines was subsequently analyzed by an amino acid analysis, the glycine and histidine residues were particularly sensitive.	Glycine	112-119	superoxide dismutase 1	Homo sapiens	11-14
15166575-8	2004	NR1A/2A EC50 values were 8.0 microM/12 microM for glutamate/glycine and 3.5 nM for Ultiva, and NR1A/2B EC50 values were 3.9 microM/1.9 microM for glutamate/glycine and 0.82 microM for Ultiva.	Glycine	60-67	thyroid hormone receptor beta	Homo sapiens	0-6
15166575-8	2004	NR1A/2A EC50 values were 8.0 microM/12 microM for glutamate/glycine and 3.5 nM for Ultiva, and NR1A/2B EC50 values were 3.9 microM/1.9 microM for glutamate/glycine and 0.82 microM for Ultiva.	Glycine	156-163	thyroid hormone receptor beta	Homo sapiens	0-6
15031290-8	2004	The ability of Zn2+ and protons to regulate the rate of glycine transport by interacting with residues situated in ECL4 of GLYT1b suggests that this region may influence the substrate translocation mechanism.	Glycine	56-63	solute carrier family 6 member 9 S homeolog	Xenopus laevis	123-129
15185439-2	2004	the mutations responsible are located in the CACNA1S gene (type 1) and in the SCN4A gene (type 2), and are all missense mutations where arginine is mostly replaced by histidine or sometimes glycine.	Glycine	190-197	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	45-52
15044467-12	2004	In this study, we purified the R213G EC-SOD variant from heterozygous or homozygous individuals and determined the C-terminal residue of the processed subunit to be Gly(213).	Glycine	165-168	superoxide dismutase 3	Homo sapiens	37-43
15113199-2	2004	Here for the first time we measured the strength of such a bond, using vibrational frequency shifts of a dimeric and nondimeric variants of GPA containing a Gly CD2 label.	Glycine	157-160	glycophorin A (MNS blood group)	Homo sapiens	140-143
15150094-4	2004	In this study, we examined the effect of colon tumor-associated mutations within the B-Raf glycine-rich loop (G loop) on MEK/Erk and NFkappaB signaling and on the transformation of NIH3T3 fibroblasts or IEC-6 intestinal epithelial cells.	Glycine	91-98	Eph receptor B1	Rattus norvegicus	125-128
15102942-0	2004	The role of glycine residues in the function of human organic anion transporter 4.	Glycine	12-19	solute carrier family 22 member 11	Homo sapiens	54-81
15017136-9	2004	In rhodopsin containing 2-(13)C Gly121 and U-(13)C Trp265, we do not observe a Trp-Gly cross peak in the DARR spectrum despite their close proximity (3.6 A) in the crystal structure.	Glycine	32-35	rhodopsin	Homo sapiens	3-12
15099830-1	2004	Equilibrium binding dynamics is studied for a panel of benzimidazole-containing compounds at the remodeled interface between human growth hormone (hGH) and the extracellular domain of its receptor (hGHbp), engineered by mutating to glycine hot spot residues T175 from the hormone and W104 from the receptor.	Glycine	232-239	growth hormone 1	Homo sapiens	131-145
15041214-4	2004	The ScFv was generated from a hybridoma cell line (11D2) specific to the WEE virus E1 glycoprotein and is arranged in the V(L)-V(H) orientation with a (gly(4)ser)(3) linker.	Glycine	86-89	immunglobulin heavy chain variable region	Homo sapiens	4-8
15082791-5	2004	The rpb2 suppressor encodes a glycine-369 --&gt; serine (G369S) replacement, located in the "lobe" domain of Rpb2 and near the Rpb9 subunit, which was identified previously as an effector of start site selection.	Glycine	30-37	DNA-directed RNA polymerase II core subunit RPB2	Saccharomyces cerevisiae S288C	4-8
15082791-5	2004	The rpb2 suppressor encodes a glycine-369 --&gt; serine (G369S) replacement, located in the "lobe" domain of Rpb2 and near the Rpb9 subunit, which was identified previously as an effector of start site selection.	Glycine	30-37	DNA-directed RNA polymerase II core subunit RPB2	Saccharomyces cerevisiae S288C	109-113
15082770-7	2004	Glyt1 encodes a membrane transporter that regulates the glycine concentration in synaptic junctions.	Glycine	56-63	solute carrier family 6 member 9	Homo sapiens	0-5
15102942-2	2004	In this study, we investigated the role of conserved glycine residues in hOAT4 function.	Glycine	53-60	solute carrier family 22 member 11	Homo sapiens	73-78
14978032-7	2004	Competition studies with glycine and l-histidine indicate that copper binds to Abeta-(1-28) at pH 7.4 with an affinity of K(a) approximately 10(7) m(-1).	Glycine	25-32	amyloid beta precursor protein	Homo sapiens	79-84
15033338-3	2004	In SOD1(-)/G93A(-) or SOD1(+) mice glycine evoked [(3)H]d-ASP and [(3)H]GABA release, while GABA caused [3H]D-ASP, but not [3H]glycine, release.	Glycine	35-42	superoxide dismutase 1, soluble	Mus musculus	3-7
15033338-3	2004	In SOD1(-)/G93A(-) or SOD1(+) mice glycine evoked [(3)H]d-ASP and [(3)H]GABA release, while GABA caused [3H]D-ASP, but not [3H]glycine, release.	Glycine	35-42	superoxide dismutase 1, soluble	Mus musculus	22-26
15033338-7	2004	The release of endogenous glutamate and GABA was also enhanced in asymptomatic animals; the glycine-evoked release of endogenous glutamate, but not of endogenous GABA, was higher in SOD1-G93A(+) than in SOD1(+) animals.	Glycine	92-99	superoxide dismutase 1, soluble	Mus musculus	182-186
15033338-7	2004	The release of endogenous glutamate and GABA was also enhanced in asymptomatic animals; the glycine-evoked release of endogenous glutamate, but not of endogenous GABA, was higher in SOD1-G93A(+) than in SOD1(+) animals.	Glycine	92-99	superoxide dismutase 1, soluble	Mus musculus	203-207
15981923-3	2004	In this study, it was first verified that monkey intestine transports a model dipeptide, Gly-Sar, in a proton-dependent manner (0.30 +/- 0.05 pmol cm(-2) s(-1) at pH 6.0 and 0.10 +/- 0.03 pmol cm(-2) s(-1) at pH 7.4) in the absorptive direction, presumably by monkey PEPT1.	Glycine	89-92	solute carrier family 15 member 1	Homo sapiens	267-272
15981923-7	2004	Functional comparison of human and monkey peptide transporters expressed in HeLa cells suggested that functionalities of PEPT1 and PEPT2 were largely conserved in terms of Gly-Sar uptake kinetics and inhibitor specificity (for most tested substrates).	Glycine	172-175	solute carrier family 15 member 1	Homo sapiens	121-126
15981923-7	2004	Functional comparison of human and monkey peptide transporters expressed in HeLa cells suggested that functionalities of PEPT1 and PEPT2 were largely conserved in terms of Gly-Sar uptake kinetics and inhibitor specificity (for most tested substrates).	Glycine	172-175	solute carrier family 15 member 2	Homo sapiens	131-136
15094065-1	2004	The three genes hTAF(II)68, EWS, and TLS (called the TET family) encode related RNA binding proteins containing an RNA recognition motif and three glycine-, arginine-, and proline-rich regions in the C-terminus and a degenerated repeat containing the consensus sequence Ser-Tyr-Gly-Gln-Ser in the N-terminus.	Glycine	147-154	FUS RNA binding protein	Homo sapiens	37-40
14766747-3	2004	When overexpressed in Escherichia coli, AtSOX enhanced growth on sarcosine as sole nitrogen source, showing that it has SOX activity in vivo, and the recombinant protein catalyzed the oxidation of sarcosine to glycine, formaldehyde, and H(2) O(2) in vitro.	Glycine	210-217	sulfite oxidase	Arabidopsis thaliana	40-45
14766747-3	2004	When overexpressed in Escherichia coli, AtSOX enhanced growth on sarcosine as sole nitrogen source, showing that it has SOX activity in vivo, and the recombinant protein catalyzed the oxidation of sarcosine to glycine, formaldehyde, and H(2) O(2) in vitro.	Glycine	210-217	sulfite oxidase	Arabidopsis thaliana	42-45
15094065-1	2004	The three genes hTAF(II)68, EWS, and TLS (called the TET family) encode related RNA binding proteins containing an RNA recognition motif and three glycine-, arginine-, and proline-rich regions in the C-terminus and a degenerated repeat containing the consensus sequence Ser-Tyr-Gly-Gln-Ser in the N-terminus.	Glycine	278-281	FUS RNA binding protein	Homo sapiens	37-40
14736867-2	2004	In this paper, we report that mutating serine 171 within gamma2 to glycine or cysteine prevents the interaction of gamma2 with alpha2 and beta1 when these subunits are co-expressed in human embryo kidney 293 cells, resulting in intracellular retention of gamma2.	Glycine	67-74	tryptophanyl-tRNA synthetase 1	Homo sapiens	57-63
15285800-10	2004	Bioassays of hippocampal neurons with the microglia-conditioned medium indicated that Abeta elevated a NMDA receptor agonist that was sensitive to an antagonist of the D-serine/glycine site (5,7-dicholorokynurenic acid; DCKA) and to enzymatic degradation of D-amino acids by D-amino acid oxidase (DAAOx).	Glycine	177-184	amyloid beta precursor protein	Homo sapiens	86-91
14736867-2	2004	In this paper, we report that mutating serine 171 within gamma2 to glycine or cysteine prevents the interaction of gamma2 with alpha2 and beta1 when these subunits are co-expressed in human embryo kidney 293 cells, resulting in intracellular retention of gamma2.	Glycine	67-74	tryptophanyl-tRNA synthetase 1	Homo sapiens	115-121
14761940-6	2004	The interaction between Rsp5 and Rvs167 is mediated through Rsp5 WW domains and PXY motifs in the central Gly-Pro-Ala-rich domain of Rvs167.	Glycine	106-109	amphiphysin	Saccharomyces cerevisiae S288C	33-39
14761940-6	2004	The interaction between Rsp5 and Rvs167 is mediated through Rsp5 WW domains and PXY motifs in the central Gly-Pro-Ala-rich domain of Rvs167.	Glycine	106-109	amphiphysin	Saccharomyces cerevisiae S288C	133-139
14736867-2	2004	In this paper, we report that mutating serine 171 within gamma2 to glycine or cysteine prevents the interaction of gamma2 with alpha2 and beta1 when these subunits are co-expressed in human embryo kidney 293 cells, resulting in intracellular retention of gamma2.	Glycine	67-74	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	138-143
14736867-2	2004	In this paper, we report that mutating serine 171 within gamma2 to glycine or cysteine prevents the interaction of gamma2 with alpha2 and beta1 when these subunits are co-expressed in human embryo kidney 293 cells, resulting in intracellular retention of gamma2.	Glycine	67-74	tryptophanyl-tRNA synthetase 1	Homo sapiens	115-121
16120360-4	2004	We identified two different heteroplasmic mutations in the mtDNA of two subjects: G4298A in the tRNA(Ala) (Alanine) gene and T10010C in the tRNA(Gly) (Glycine), both of which have been reported previously.	Glycine	151-158	mitochondrially encoded tRNA glycine	Homo sapiens	140-149
15086344-5	2004	Here, we describe for the first time a single nucleotide polymorphism in exon 5 of the immunoglobulin A Fc receptor (FCAR) gene leading to a Ser--&gt;Gly substitution at position 248 of the mature FcalphaRI protein.	Glycine	150-153	CD79a molecule	Homo sapiens	87-103
15086344-5	2004	Here, we describe for the first time a single nucleotide polymorphism in exon 5 of the immunoglobulin A Fc receptor (FCAR) gene leading to a Ser--&gt;Gly substitution at position 248 of the mature FcalphaRI protein.	Glycine	150-153	Fc alpha receptor	Homo sapiens	117-121
15042566-5	2004	In DNA from the breast and liver tumors the authors showed the same missense mutation in codon 245 (GGC--&gt;GAC; Gly--&gt;Asp) of exon 7 of p53.	Glycine	114-117	tumor protein p53	Homo sapiens	141-144
14680478-5	2004	However, the mutants P167G (Pro167--&gt;Gly), P167A and P167C were expressed at lower levels compared with wild-type NHE1, and a significant portion of P167G and P167C were retained intracellularly, possibly indicating induced changes in the structure of TM IV.	Glycine	40-43	solute carrier family 9 member A1	Homo sapiens	117-121
15062021-8	2004	(4) Increases in intracellular calcium and production of TNF-alpha by isolated Kupffer cells stimulated by endotoxin were elevated significantly by hemorrhagic shock, which were totally prevented by glycine (P &lt; 0.01).	Glycine	199-206	tumor necrosis factor	Rattus norvegicus	57-66
15035617-7	2004	To probe this further, the structural consequences of the glycine linker and its interaction with PTH1 were examined by circular dichroism, (1)H NMR, and extensive ligand/receptor molecular dynamics simulations.	Glycine	58-65	parathyroid hormone	Homo sapiens	98-102
15062021-9	2004	CONCLUSION: Glycine reduces organ injury and mortality caused by hemorrhagic shock by preventing increase of intracellular calcium and production of TNF-alpha of Kupffer cells and blocking systemic inflammation responses.	Glycine	12-19	tumor necrosis factor	Rattus norvegicus	149-158
15025513-10	2004	In conclusion, gastric nitrosation of glycine derivatives such as peptides with a N-terminal glycine might produce ECHA analogues that alkylate bases of gastric mucosal DNA and thereby initiate gastric cancer.	Glycine	38-45	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha	Homo sapiens	115-119
15152943-10	2004	The relative role of the conservative leucines and glycines in MRP1 indicates a similar three-dimensional structure within the catalytic center of various ABC proteins.	Glycine	51-59	ATP binding cassette subfamily C member 1	Homo sapiens	63-67
15025513-10	2004	In conclusion, gastric nitrosation of glycine derivatives such as peptides with a N-terminal glycine might produce ECHA analogues that alkylate bases of gastric mucosal DNA and thereby initiate gastric cancer.	Glycine	93-100	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha	Homo sapiens	115-119
15027101-4	2004	Glycine was administered at a dose of 0.6 g kg(-1) body weight to rats with alcohol-induced liver injury, which significantly decreased the levels of TBARS and significantly elevated the activities of SOD, CAT, GSH, GPx and GR in the erythrocyte membrane, plasma and hepatocytes as compared to that of untreated alcohol supplemented rats.	Glycine	0-7	catalase	Rattus norvegicus	206-209
15049841-4	2004	Altogether, we found that replacing glycine with silaproline (Sip) in position 9 of SP leads to a potent analogue exhibiting an increased resistance to angiotensin-converting enzyme hydrolysis.	Glycine	36-43	tachykinin precursor 1	Homo sapiens	84-86
15832510-6	2004	The [14C]Gly-Sar uptake in the transfected cells was sodium-independent and pH-dependent, demonstrating enhanced uptake, the rate of which increased significantly from the weakly to strongly expressing hPepT1 MDCK/hPepT1 -V5&amp;His clones as compared to the mock cell line at pH 6.0.	Glycine	9-12	solute carrier family 15 member 1	Homo sapiens	202-208
14990700-3	2004	We now show that a region of moderate hydrophobicity we call the hydrophobic patch (HP), present in the small N-terminal ectodomain of p10, shares the following characteristics with the fusion peptides of enveloped virus fusion proteins: (i) an abundance of glycine and alanine residues, (ii) a potential amphipathic secondary structure, (iii) membrane-seeking characteristics that correspond to the degree of hydrophobicity, and (iv) the ability to induce lipid mixing in a liposome fusion assay.	Glycine	258-265	S100 calcium binding protein A10	Homo sapiens	135-138
14960371-5	2004	NR1 prefers smaller ligands (glycine, serine, and alanine) in comparison with GluRB and GluR0 that bind l-glutamate: the bulky side chain of W731 in NR1 dramatically reduces the size of the ligand-binding site, functioning to selectively restrict recognition to glycine and the d-isomers of serine and alanine.	Glycine	262-269	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	78-83
15832510-6	2004	The [14C]Gly-Sar uptake in the transfected cells was sodium-independent and pH-dependent, demonstrating enhanced uptake, the rate of which increased significantly from the weakly to strongly expressing hPepT1 MDCK/hPepT1 -V5&amp;His clones as compared to the mock cell line at pH 6.0.	Glycine	9-12	solute carrier family 15 member 1	Homo sapiens	214-220
15037197-9	2004	Our results, using a yeast expression system, demonstrate that substituting glycine 154 of hENT1 with serine of hENT2 converts hENT1 to a transporter that exhibits partial characteristics of hENT2.	Glycine	76-83	solute carrier family 29 member 2	Homo sapiens	112-117
14751229-1	2004	Myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyzes the covalent attachment of myristate to the N-terminal of the glycine residue of various eukaryotic and viral proteins of diverse functions.	Glycine	123-130	N-myristoyltransferase 1	Homo sapiens	46-49
15134871-7	2004	HPLC analysis showed that ACE cleaved SP at Phe(8)-Gly(9) and Gly(9)-Leu(10) to release C-terminal tri- and dipeptide (ratio = 4:1).	Glycine	51-54	angiotensin I converting enzyme	Homo sapiens	26-29
15134871-7	2004	HPLC analysis showed that ACE cleaved SP at Phe(8)-Gly(9) and Gly(9)-Leu(10) to release C-terminal tri- and dipeptide (ratio = 4:1).	Glycine	62-65	angiotensin I converting enzyme	Homo sapiens	26-29
14645232-1	2004	Glycine specifically induces genes encoding subunits of the glycine decarboxylase complex (GCV1, GCV2, and GCV3), and this is mediated by a fall in cytoplasmic levels of 5,10-methylenetetrahydrofolate caused by inhibition of cytoplasmic serine hydroxymethyltransferase.	Glycine	0-7	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	91-95
14764898-7	2004	Immunocytochemical and immunoprecipitation analyses demonstrated that Keap1 associates with actin filaments in the cytoplasm through its double glycine repeat domain.	Glycine	144-151	kelch like ECH associated protein 1	Homo sapiens	70-75
14572308-1	2004	Rat intestinal mucin Muc3 (rMuc3), like its human homologue (MUC3) and several other membrane mucins, contains a C-terminally located SEA (sea urchin sperm protein, enterokinase and agrin) module, with an intrinsic proteolytic site sequence G downward arrow SIVV (where G downward arrow S is the glycine serine cleavage site).	Glycine	296-303	MUC3	Homo sapiens	21-25
15037197-9	2004	Our results, using a yeast expression system, demonstrate that substituting glycine 154 of hENT1 with serine of hENT2 converts hENT1 to a transporter that exhibits partial characteristics of hENT2.	Glycine	76-83	solute carrier family 29 member 2	Homo sapiens	191-196
14667816-4	2004	With DNA transfection assay, we have established the importance of the glycine-rich domain for the exon-skipping activity of TDP-43.	Glycine	71-78	TAR DNA binding protein	Homo sapiens	125-131
14720220-7	2004	Whereas glutamate levels in the media changed little, levels of D-serine and L-glycine, co-agonists at NMDA receptors, increased significantly following NT-4/5 treatment.	Glycine	77-86	neurotrophin 4	Homo sapiens	153-159
14722304-6	2004	Using a series of recombinant viruses expressing various UL99-green fluorescent protein fusions, we demonstrate that myristoylation at glycine 2 and an acidic cluster (AC; amino acids 44 to 57) are required for the punctate perinuclear and cytoplasmic (vacuole-like) localization observed for wild-type pp28.	Glycine	135-142	myristylated tegument protein	Human betaherpesvirus 5	57-61
14583623-3	2004	Here, we demonstrate that the human FIB N-terminal glycine- and arginine-rich domain (residues 1-77) and its spacer region 1 (78-132) interact with splicing factor 2-associated p32 (SF2A-p32) and that the FIB methyltransferase-like domain (133-321) interacts with protein-arginine methyltransferase 5 (PRMT5, Janus kinase-binding protein 1).	Glycine	51-58	protein arginine methyltransferase 5	Homo sapiens	264-300
14583623-3	2004	Here, we demonstrate that the human FIB N-terminal glycine- and arginine-rich domain (residues 1-77) and its spacer region 1 (78-132) interact with splicing factor 2-associated p32 (SF2A-p32) and that the FIB methyltransferase-like domain (133-321) interacts with protein-arginine methyltransferase 5 (PRMT5, Janus kinase-binding protein 1).	Glycine	51-58	protein arginine methyltransferase 5	Homo sapiens	302-307
14729624-3	2004	Consequently, we investigated the effects of overexpression of glycine-extended gastrin in a mouse strain that is prone to developing lung cancer and also examined the expression of incompletely processed gastrins in primary human lung cancers.	Glycine	63-70	gastrin	Mus musculus	80-87
15319540-6	2004	RESULTS: Gly-BSA increased PKC activity, particularly PKC-alpha and -alpha1, within 15 min of incubation with HMC, which decreased to the control value at 2 h. Gly-BSA incubated with HMC increased O2- production by 2 times vis-a-vis BSA-treated cells.	Glycine	9-12	protein kinase C alpha	Homo sapiens	27-30
15319540-6	2004	RESULTS: Gly-BSA increased PKC activity, particularly PKC-alpha and -alpha1, within 15 min of incubation with HMC, which decreased to the control value at 2 h. Gly-BSA incubated with HMC increased O2- production by 2 times vis-a-vis BSA-treated cells.	Glycine	9-12	protein kinase C alpha	Homo sapiens	54-75
15319540-6	2004	RESULTS: Gly-BSA increased PKC activity, particularly PKC-alpha and -alpha1, within 15 min of incubation with HMC, which decreased to the control value at 2 h. Gly-BSA incubated with HMC increased O2- production by 2 times vis-a-vis BSA-treated cells.	Glycine	160-163	protein kinase C alpha	Homo sapiens	27-30
15319540-6	2004	RESULTS: Gly-BSA increased PKC activity, particularly PKC-alpha and -alpha1, within 15 min of incubation with HMC, which decreased to the control value at 2 h. Gly-BSA incubated with HMC increased O2- production by 2 times vis-a-vis BSA-treated cells.	Glycine	160-163	protein kinase C alpha	Homo sapiens	54-75
14962794-8	2004	Arginine/glycine (RG)-rich domains in components of the SMN complex interact with Sm, like-Sm (LSm), fibrillarin, RNA helicase A (Gu), and coilin proteins, all of which are antigen targets in a variety of diseases.	Glycine	9-16	DExH-box helicase 9	Homo sapiens	114-128
14693408-0	2004	Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients.	Glycine	9-12	insulin	Homo sapiens	121-128
14693408-0	2004	Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients.	Glycine	13-16	insulin	Homo sapiens	121-128
14693408-0	2004	Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients.	Glycine	13-16	insulin	Homo sapiens	164-171
14693408-9	2004	However, increased sensitivity to catecholamine-induced lipolysis of the Gly allele promotes higher free fatty acids concentrations in the portal system, which could enhance the higher levels of fasting insulin.	Glycine	73-76	insulin	Homo sapiens	203-210
14962227-0	2004	Prothrombin Shanghai: hypoprothrombinaemia caused by substitution of Gla29 by Gly.	Glycine	78-81	coagulation factor II, thrombin	Homo sapiens	0-11
14962227-5	2004	Nucleotide sequencing of amplified DNA revealed a novel mutation, Glu (GAG) to Gly (GGG) at residue 29, which normally undergoes gamma-carboxylation within the Gla domain of prothrombin.	Glycine	79-82	coagulation factor II, thrombin	Homo sapiens	174-185
15381393-7	2004	Cells spreading on immobilized soluble fibrin were blocked by the exogenous addition of soluble fibrin and glycine-arginine-glycine-aspartic acid-serine-phenylalanine (GRGDSP)-synthetic peptide but not by the addition of fibrinogen or fibrin monomer.	Glycine	124-131	fibrinogen beta chain	Homo sapiens	221-231
14722247-4	2004	NR1 binds glycine, and residue Asn598 in the re-entrant membrane loop M2 largely determines NMDAR calcium permeability.	Glycine	10-17	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-3
14722247-6	2004	Here, we report that mutations of NR1(Asn598) in combination with wild-type NR2A, expressed in human embryonic kidney 293 cells, exhibit altered glycine-independent desensitization.	Glycine	145-152	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	34-37
14722247-6	2004	Here, we report that mutations of NR1(Asn598) in combination with wild-type NR2A, expressed in human embryonic kidney 293 cells, exhibit altered glycine-independent desensitization.	Glycine	145-152	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	76-80
15046561-2	2004	New APOAV missense variants (Val153 --&gt; Met and Cys185 --&gt; Gly) have been detected recently.	Glycine	65-68	apolipoprotein A5	Homo sapiens	4-9
15658192-2	2004	Hb Zurich Albisrieden [alpha59(E8)Gly-->Arg (alpha2)] is not detected at the protein level and leads to alpha(+)-thalassemia (thal).	Glycine	34-37	glycoprotein hormone subunit alpha 2	Homo sapiens	45-51
15002667-3	2004	Like Wir1 proteins, it consists of a hydrophobic N-terminal half and a hydrophilic C-terminal half relatively rich in glycine and proline.	Glycine	118-125	WIR1	Triticum aestivum	5-9
14673179-2	2004	The mechanisms involved in this process are largely unknown, although a glycine repeat in the middle of p105 has been identified as a processing stop signal.	Glycine	72-79	nuclear factor kappa B subunit 1	Homo sapiens	104-108
14532279-3	2003	Out of the remaining 19 transporters, three (F293C-, L296C-, and F297C-hPepT1) showed negligible glycyl-sarcosine (gly-sar) uptake activity and may play an important role in defining the overall hPepT1 structure.	Glycine	97-100	solute carrier family 15 member 1	Homo sapiens	71-77
14532279-8	2003	MTSET modification of R282C-hPepT1 resulted in a significant increase in gly-sar uptake.	Glycine	73-76	solute carrier family 15 member 1	Homo sapiens	28-34
14598336-11	2003	In the third family (MRX16), a Glu to Gly substitution (E137G) was found in the MBD.	Glycine	38-41	methyl-CpG binding protein 2	Homo sapiens	21-26
14506238-7	2003	In this study, we found that the amino acid sequence His-Gly-Lys (HGK) in D5H is the core motif for inhibition of adhesion and invasion of MDA-MB-231 cells in vitro.	Glycine	57-60	mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens	66-69
14684475-0	2003	In vivo characterization of changes in glycine levels induced by GlyT1 inhibitors.	Glycine	39-46	solute carrier family 6 member 9	Homo sapiens	65-70
14725353-7	2003	RESULTS: At pH 6.0, H57K-, H57R-, H121K-, and H121R-hPepT1 led to a 97%, 90%, 45%, and 75% decrease in [3H]Gly-Sar uptake into HEK293 cells, respectively.	Glycine	107-110	solute carrier family 15 member 1	Homo sapiens	52-58
14725353-9	2003	In oocytes expressing H57R-hPepT1, steady-state currents induced by 5 mM Gly-Sar increased with increasing pH (I(max) = 300 nA at pH 8.5), suggesting the binding of protons to H57R.	Glycine	73-76	solute carrier family 15 member 1	Homo sapiens	27-33
14725353-11	2003	CONCLUSIONS: H57R-hPepT1 is able to bind protons at a relatively basic pH, resulting in facilitation of transport of Gly-Sar by hPepT1 at higher pH.	Glycine	117-120	solute carrier family 15 member 1	Homo sapiens	18-24
14725353-11	2003	CONCLUSIONS: H57R-hPepT1 is able to bind protons at a relatively basic pH, resulting in facilitation of transport of Gly-Sar by hPepT1 at higher pH.	Glycine	117-120	solute carrier family 15 member 1	Homo sapiens	128-134
14633729-1	2003	N-myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the cotranslational and/or posttranslational transfer of myristate to the NH(2) terminus of the glycine residue of a number of important proteins that have diverse biological functions and thus have been proposed as potential targets for chemotherapeutic drug design.	Glycine	174-181	N-myristoyltransferase 1	Homo sapiens	0-22
14633729-1	2003	N-myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the cotranslational and/or posttranslational transfer of myristate to the NH(2) terminus of the glycine residue of a number of important proteins that have diverse biological functions and thus have been proposed as potential targets for chemotherapeutic drug design.	Glycine	174-181	N-myristoyltransferase 1	Homo sapiens	24-27
14598044-2	2003	Unique features of the GW182 protein include 39 repeats of glycine (G) and tryptophan (W) residues, binding to a subset of messenger RNA and localization to unique structures within the cytoplasm that were designated GW bodies (GWBs).	Glycine	59-66	trinucleotide repeat containing adaptor 6A	Homo sapiens	23-28
12949144-7	2003	In both species, the isopeptide bond is formed between lysine 118 of the actin and the C-terminal glycine 76 of ubiquitin.	Glycine	98-105	Actin 79B	Drosophila melanogaster	73-78
14556962-3	2003	Subsequent recognition that bovine brain contains AT(2) receptors, while dipsogenic responses to Ang II are mediated by AT1 receptors, suggests that Sar1,Gly(8) Ang II is AT1 selective.	Glycine	154-157	angiotensin II receptor type 1	Bos taurus	171-174
14622582-5	2003	Thus, during early postnatal life, GlyT1 is essential for regulating glycine concentrations at inhibitory GlyRs, and GlyT1 deletion generates symptoms found in human glycine encephalopathy.	Glycine	69-76	solute carrier family 6 member 9	Homo sapiens	35-40
14622582-5	2003	Thus, during early postnatal life, GlyT1 is essential for regulating glycine concentrations at inhibitory GlyRs, and GlyT1 deletion generates symptoms found in human glycine encephalopathy.	Glycine	166-173	solute carrier family 6 member 9	Homo sapiens	35-40
14622582-5	2003	Thus, during early postnatal life, GlyT1 is essential for regulating glycine concentrations at inhibitory GlyRs, and GlyT1 deletion generates symptoms found in human glycine encephalopathy.	Glycine	166-173	solute carrier family 6 member 9	Homo sapiens	117-122
14661916-7	2003	Also, Lys-FITC-OCH3 (100 microM) uptake in HeLa/hPept1 and Caco-2 cells was reduced by 77% and 80%, respectively, in the presence of 1 mM Gly-Sar.	Glycine	138-141	solute carrier family 15 member 1	Homo sapiens	48-54
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	119-122	Thioredoxin reductase-1	Drosophila melanogaster	64-68
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	131-134	Thioredoxin reductase-1	Drosophila melanogaster	64-68
12922151-1	2003	Since RGD peptides (R: arginine; G: glycine; D: aspartic acid) have been found to promote cell adhesion in 1984 (Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule, Nature 309 (1984) 30), numerous materials have been RGD functionalized for academic studies or medical applications.	Glycine	36-43	fibronectin 1	Homo sapiens	141-152
14661916-5	2003	RESULTS: In HeLa/hPept1 cells, [3H]Gly-Sar uptake was significantly inhibited by Lys-FITC-OCH3 (74%) but not by FITC-Val-OCH3 (22%).	Glycine	35-38	solute carrier family 15 member 1	Homo sapiens	17-23
12923815-1	2003	A positron-emitter (carbon-11) labeled antagonist for the glycine-binding site of NMDA receptors, [(11)C]L-703,717, has a unique in vivo binding characteristic, in which it preferentially binds to cerebellar-specific NMDA receptors consisting of a GluRepsilon3 subunit and eventually accumulates in rodent cerebellum under in vivo conditions, but not under in vitro conditions.	Glycine	58-65	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	Mus musculus	248-260
14568540-1	2003	Crystal structures of P1 Gly, Val, Leu and Phe bovine pancreatic trypsin inhibitor (BPTI) variants in complex with two serine proteinases, bovine trypsin and chymotrypsin, have been determined.	Glycine	25-28	trophoblast Kunitz domain protein 1	Bos taurus	65-82
14523231-4	2003	In one family, we identified a T599 --&gt; A mutation changing an isoleucine into a lysine residue (I200K) within the glycine/serine (GS) domain of BMPR1B, a region involved in phosphorylation of the receptor.	Glycine	118-125	bone morphogenetic protein receptor type 1B	Homo sapiens	148-154
12904305-7	2003	In a previous study, substitution of the second amino acid residue threonine for glycine in TIMP-1, which confers selective MMP inhibition, was shown to obliterate its anti-apoptotic activity in activated hepatic stellate cells suggesting that the anti-apoptotic activity of TIMP-1 is dependent on MMP inhibition.	Glycine	81-88	TIMP metallopeptidase inhibitor 1	Homo sapiens	92-98
12890687-5	2003	The interaction of Apg10p with Apg12p is dependent on the carboxyl-terminal glycine of Apg12p.	Glycine	76-83	autophagy related 10	Mus musculus	19-25
12890687-5	2003	The interaction of Apg10p with Apg12p is dependent on the carboxyl-terminal glycine of Apg12p.	Glycine	76-83	autophagy related 12	Homo sapiens	31-37
12890687-5	2003	The interaction of Apg10p with Apg12p is dependent on the carboxyl-terminal glycine of Apg12p.	Glycine	76-83	autophagy related 12	Homo sapiens	87-93
12904305-7	2003	In a previous study, substitution of the second amino acid residue threonine for glycine in TIMP-1, which confers selective MMP inhibition, was shown to obliterate its anti-apoptotic activity in activated hepatic stellate cells suggesting that the anti-apoptotic activity of TIMP-1 is dependent on MMP inhibition.	Glycine	81-88	TIMP metallopeptidase inhibitor 1	Homo sapiens	275-281
14519785-7	2003	TRAIL-induced apoptosis was completely prevented by Gln, but not inhibited by other amino acids, including the GSH constituents, glutamate, cysteine and glycine.	Glycine	153-160	TNF superfamily member 10	Homo sapiens	0-5
14512880-12	2003	In conclusion, glycine-conjugated and free bile acids suppress bile acid synthesis and mRNA levels of CYP7A1 in the order CDCA &gt; DCA &gt; CA &gt; UDCA.	Glycine	15-22	cytochrome P450 family 7 subfamily A member 1	Homo sapiens	102-108
14511639-1	2003	The fragile X mental retardation protein (FMRP) contains three RNA binding domains, two of which the KH2 domain and the C-terminal arginine-glycine-rich (RG-rich) region participate in RNA binding.	Glycine	140-147	fragile X messenger ribonucleoprotein 1	Homo sapiens	4-40
14511639-1	2003	The fragile X mental retardation protein (FMRP) contains three RNA binding domains, two of which the KH2 domain and the C-terminal arginine-glycine-rich (RG-rich) region participate in RNA binding.	Glycine	140-147	fragile X messenger ribonucleoprotein 1	Homo sapiens	42-46
12963052-3	2003	The GlyT1 transport inhibitors sarcosine, ALX-5407, and Org-24598 were tested and shown to block [14C]glycine uptake with expected IC50 values of 37.5+/-4.6 microM, 2.8+/-0.6 nM, and 6.9+/-0.9 nM, respectively.	Glycine	97-109	solute carrier family 6 member 9	Homo sapiens	4-9
12963061-4	2003	The desired sequences were C6-(Gly-Pro-Hyp)5-Gly-Pro-[Amp/Adp]-Gly-Pro-Gln-Gly approximately Leu-Arg-Gly-Gln-Lys(Dnp)-Gly-Val-Arg-(Gly-Pro-Hyp)5-NH2.	Glycine	31-34	adenine phosphoribosyltransferase	Homo sapiens	54-57
12939651-6	2003	A Gly/Ala substitution at position 160 of the NFATC4 protein (G160A) was associated with left ventricular mass and wall thickness (P=0.02 and 0.006, respectively, GA+AA vs GG), the minor allele (Ala) being associated with lower mean values of these parameters.	Glycine	2-5	nuclear factor of activated T cells 4	Homo sapiens	46-52
13130130-2	2003	GW182 was characterized by multiple glycine(G)-tryptophan(W) repeats and an RNA recognition motif (RRM) that bound a subset of HeLa cell messenger RNAs (mRNAs).	Glycine	36-43	trinucleotide repeat containing adaptor 6A	Homo sapiens	0-5
14499862-4	2003	RESULTS: A novel missense mutation, G to A at position 154 in the KCNE1 gene was identified in a Chinese Long QT syndrome family, which leads to an amino acid substitution of arginine (R) for glycine (G) at position 52 (G52R-KCNE1).	Glycine	192-199	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	66-71
14499862-4	2003	RESULTS: A novel missense mutation, G to A at position 154 in the KCNE1 gene was identified in a Chinese Long QT syndrome family, which leads to an amino acid substitution of arginine (R) for glycine (G) at position 52 (G52R-KCNE1).	Glycine	192-199	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	225-230
14562417-8	2003	CONCLUSION: Reduction of TNF-alpha, ET-1 and NO contents in plasma and liver tissue of rats fed on glycine may be helpful to alleviate pathological lesions in obstructive jaundice.	Glycine	99-106	tumor necrosis factor	Rattus norvegicus	25-34
14562417-8	2003	CONCLUSION: Reduction of TNF-alpha, ET-1 and NO contents in plasma and liver tissue of rats fed on glycine may be helpful to alleviate pathological lesions in obstructive jaundice.	Glycine	99-106	endothelin 1	Rattus norvegicus	36-40
12941885-0	2003	Palmitoylation, membrane-proximal basic residues, and transmembrane glycine residues in the reovirus p10 protein are essential for syncytium formation.	Glycine	68-75	S100 calcium binding protein A10	Homo sapiens	101-104
12949723-8	2003	Further, dietary glycine largely prevented increases in IL-1beta and TNF-alpha in the colon 2 days after TNBS, and TNBS induction of CINC and MIP-2 in the colonic tissue also was abrogated by glycine.	Glycine	17-24	interleukin 1 beta	Rattus norvegicus	56-64
12949723-8	2003	Further, dietary glycine largely prevented increases in IL-1beta and TNF-alpha in the colon 2 days after TNBS, and TNBS induction of CINC and MIP-2 in the colonic tissue also was abrogated by glycine.	Glycine	17-24	tumor necrosis factor	Rattus norvegicus	69-78
14658759-6	2003	This SNP was deduced to substitute serine (OLETF) for glycine (F344 and LETO) at the 195 amino acid residue within the protease domain of rat Capn10.	Glycine	54-61	calpain 10	Rattus norvegicus	142-148
14555933-11	2003	Pro-apoptotic bax and caspase-3 were downregulated, whereas bcl-2 was upregulated in the glycine-treated animals (P&lt;.02).	Glycine	89-96	BCL2, apoptosis regulator	Rattus norvegicus	60-65
12925722-0	2003	A glycine to aspartic acid substitution of COL2A1 in a family with the Strudwick variant of spondyloepimetaphyseal dysplasia.	Glycine	2-9	collagen type II alpha 1 chain	Homo sapiens	43-49
12958650-4	2003	Phosphorylation of MLC(20) was detected by Gly-PAGE and Scoin Image Software, and Mg(2+)-ATPase activity of myosin was measured with spectrophotometry.	Glycine	43-46	myosin light chain 12B	Homo sapiens	19-26
12741957-2	2003	At least three variant forms of ABCG2 have been hitherto documented on the basis of their amino acid moieties (i.e., arginine, glycine and threonine) at position 482.	Glycine	127-134	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	32-37
12911299-8	2003	Finally, we have used mutational analysis to establish the importance of a glycine within the linker that connects the two lobes of Sky1p.	Glycine	75-82	serine/threonine protein kinase SKY1	Saccharomyces cerevisiae S288C	132-137
12853105-2	2003	In an attempt to identify high potency NOP agonists for use in the brain we have compared the activity of a novel N/OFQ analogue [Phe(1)Psi(CH(2)-O)Gly(2)]N/OFQ(1-13)NH(2) ([F/G-O]) with the existing [Phe(1)Psi(CH(2)-NH)Gly(2)]N/OFQ(1-13)NH(2) ([F/G]).	Glycine	148-151	prepronociceptin	Homo sapiens	114-119
12771150-2	2003	A cyclic closed-chain dodecapeptide mimicking the conformation-specific domain of CXCR4 (cDDX4) was prepared in which Gly-Asp, as the dipeptide forming a spacer arm, links the amino and carboxyl termini of the decapeptidyl linear chain (linear DDX4, Asn176 to Ile185) derived from the undecapeptidyl arch (UPA; Asn176 to Cys186) of extracellular loop 2 (ECL-2) in CXCR4.	Glycine	118-121	DEAD-box helicase 4	Homo sapiens	90-94
12741957-4	2003	Exogenous expression of the Arg(482), Gly(482), and Thr(482) variant forms of ABCG2 conferred HEK-293 cell resistance toward mitoxantrone 15-, 47- and 54-fold, respectively, as compared with mock-transfected HEK-293 cells.	Glycine	38-41	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	78-83
12899688-2	2003	The ts21-66 mutant contains two substitutions in the coat protein (Ile21--&gt;Thr and Asp66--&gt;Gly) and, in contrast with U1, induces a hypersensitive response (formation of necroses) on the leaves of plants bearing a host resistance gene N" (for example Nicotiana sylvestris); TMV U1 induces systemic infection (mosaic) on the leaves of such plants.	Glycine	97-100	golgi phosphoprotein 3	Homo sapiens	53-65
12756249-8	2003	Further adhesion experiments demonstrated that binding of trophoblast cells to fibronectin was completely inhibited by a peptide of the Arg-Gly-Asp (RGD) sequence, which binds to integrins alpha5beta1, alphaVbeta1, alphaVbeta3, and alphaVbeta5, whereas non-binding peptide containing Arg-Gly-Glu (RGE) had minimal effects.	Glycine	140-143	fibronectin 1	Homo sapiens	79-90
12930744-8	2003	Two different glycine residues (G(102) and G(112)) are replaced by aspartic acid and both are in the unstructured region of RPL4 that lines the peptide exit tunnel of the chloroplast ribosome.	Glycine	14-21	ribosomal protein L4	Chlamydomonas reinhardtii	124-128
12759346-0	2003	Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation.	Glycine	80-87	myeloperoxidase	Homo sapiens	31-46
12808093-4	2003	In addition, a mutant of PED/PEA-15 featuring the substitution of Ser(116)--&gt;Gly (PED(S116--&gt;G)) showed 10-fold-decreased phosphorylation by Akt.	Glycine	80-83	AKT serine/threonine kinase 1	Homo sapiens	147-150
12895268-2	2003	Our aim was to investigate the ability of the amino acid glycine to prevent hepatic damage induced by injection of lipopolysaccharide and d-galactosamine (d-Gal), to modulate pro- and anti-inflammatory cytokine levels, and to improve survival.	Glycine	57-64	galanin and GMAP prepropeptide	Mus musculus	157-160
12895268-8	2003	RESULTS: In the glycine-treated mice, the serum levels of liver enzymes and TNF-alpha, the histologic necroinflammation score and the mortality rate were significantly reduced compared to control mice (P&lt;0.001).	Glycine	16-23	tumor necrosis factor	Mus musculus	76-85
12895268-9	2003	Serum IL-10 levels in the glycine-treated mice were increased (P&lt;0.01).	Glycine	26-33	interleukin 10	Mus musculus	6-11
12895268-10	2003	In vitro studies in cultured lymphocytes isolated from either normal or glycine pretreated mice, demonstrated a significant and dose-dependent inhibition of LPS-induced TNF-alpha secretion and increase in IL-10 response after treatment with glycine (P&lt;0.01).	Glycine	72-79	tumor necrosis factor	Mus musculus	169-178
12895268-10	2003	In vitro studies in cultured lymphocytes isolated from either normal or glycine pretreated mice, demonstrated a significant and dose-dependent inhibition of LPS-induced TNF-alpha secretion and increase in IL-10 response after treatment with glycine (P&lt;0.01).	Glycine	72-79	interleukin 10	Mus musculus	205-210
14524041-7	2003	Following binding to a peptide (Gly-Pro-Arg-Pro-Lys), fibrinogen and fibrin were specifically removed from the patient"s plasma: her fibrinogen concentration was lowered from an original mean level of 310 mg/dl (SD +/- 104 mg/dl) to 136 mg/dl (SD +/- 54 mg/dl), and there was no return to the baseline concentration by the time of the next fibrinogen adsorption session.	Glycine	32-35	fibrinogen beta chain	Homo sapiens	54-64
14524041-7	2003	Following binding to a peptide (Gly-Pro-Arg-Pro-Lys), fibrinogen and fibrin were specifically removed from the patient"s plasma: her fibrinogen concentration was lowered from an original mean level of 310 mg/dl (SD +/- 104 mg/dl) to 136 mg/dl (SD +/- 54 mg/dl), and there was no return to the baseline concentration by the time of the next fibrinogen adsorption session.	Glycine	32-35	fibrinogen beta chain	Homo sapiens	133-143
14524041-7	2003	Following binding to a peptide (Gly-Pro-Arg-Pro-Lys), fibrinogen and fibrin were specifically removed from the patient"s plasma: her fibrinogen concentration was lowered from an original mean level of 310 mg/dl (SD +/- 104 mg/dl) to 136 mg/dl (SD +/- 54 mg/dl), and there was no return to the baseline concentration by the time of the next fibrinogen adsorption session.	Glycine	32-35	fibrinogen beta chain	Homo sapiens	133-143
12874010-0	2003	Radiochemical investigations of gastrin-releasing peptide receptor-specific [(99m)Tc(X)(CO)3-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH2)] in PC-3, tumor-bearing, rodent models: syntheses, radiolabeling, and in vitro/in vivo studies where Dpr = 2,3-diaminopropionic acid and X = H2O or P(CH2OH)3.	Glycine	125-128	gastrin releasing peptide receptor	Homo sapiens	32-66
12711608-6	2003	Here we show that creation of a phosphate binding motif through the introduction of glycines at positions 79, 81, and 84 in Acr2p resulted in a gain of phosphotyrosine phosphatase activity and a loss of arsenate reductase activity.	Glycine	84-92	Arr2p	Saccharomyces cerevisiae S288C	124-129
12895268-10	2003	In vitro studies in cultured lymphocytes isolated from either normal or glycine pretreated mice, demonstrated a significant and dose-dependent inhibition of LPS-induced TNF-alpha secretion and increase in IL-10 response after treatment with glycine (P&lt;0.01).	Glycine	241-248	tumor necrosis factor	Mus musculus	169-178
12895268-10	2003	In vitro studies in cultured lymphocytes isolated from either normal or glycine pretreated mice, demonstrated a significant and dose-dependent inhibition of LPS-induced TNF-alpha secretion and increase in IL-10 response after treatment with glycine (P&lt;0.01).	Glycine	241-248	interleukin 10	Mus musculus	205-210
12895268-12	2003	The protective effect of glycine is associated with modulation of TNF-alpha and IL-10 secretion.	Glycine	25-32	tumor necrosis factor	Mus musculus	66-75
12895268-12	2003	The protective effect of glycine is associated with modulation of TNF-alpha and IL-10 secretion.	Glycine	25-32	interleukin 10	Mus musculus	80-85
12859184-2	2003	Glycine N-methyltransferase (GNMT) catalyzes the S-adenosyl-l-methionine- (SAM-) dependent methylation of glycine to form sarcosine.	Glycine	106-113	glycine N-methyltransferase	Homo sapiens	0-27
12859184-2	2003	Glycine N-methyltransferase (GNMT) catalyzes the S-adenosyl-l-methionine- (SAM-) dependent methylation of glycine to form sarcosine.	Glycine	106-113	glycine N-methyltransferase	Homo sapiens	29-33
12697024-1	2003	Glycine N-methyltransferase (GNMT) is an abundant cytosolic enzyme that catalyses the methylation of glycine into sarcosine, coupled with conversion of the methyl donor, S -adenosylmethionine (AdoMet), into S -adenosylhomocysteine (AdoHcy).	Glycine	101-108	glycine N-methyltransferase	Homo sapiens	0-27
12697024-1	2003	Glycine N-methyltransferase (GNMT) is an abundant cytosolic enzyme that catalyses the methylation of glycine into sarcosine, coupled with conversion of the methyl donor, S -adenosylmethionine (AdoMet), into S -adenosylhomocysteine (AdoHcy).	Glycine	101-108	glycine N-methyltransferase	Homo sapiens	29-33
12788085-7	2003	Y167C-, N171C-, and S174C-hPepT1 showed &lt;/=25% Gly-Sar uptake when compared with WT-hPepT1.	Glycine	50-53	solute carrier family 15 member 1	Homo sapiens	26-32
12686554-6	2003	Second, some activation loop mutants, such as a single residue deletion or replacing all residues with Gly, exhibited 1-2% of wild type (wt) activity toward artificial substrates, but significantly higher activity toward Src.	Glycine	103-106	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	221-224
12805203-2	2003	NMDA receptors require both glycine and glutamate for activation with NR1 and NR2 forming glycine and glutamate sites, respectively.	Glycine	28-35	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	70-73
12805203-2	2003	NMDA receptors require both glycine and glutamate for activation with NR1 and NR2 forming glycine and glutamate sites, respectively.	Glycine	90-97	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	70-73
12805203-4	2003	Here, we describe the cocrystal structures of the NR1 S1S2 ligand-binding core with the agonists glycine and D-serine (DS), the partial agonist D-cycloserine (DCS) and the antagonist 5,7-dichlorokynurenic acid (DCKA).	Glycine	97-104	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	50-53
12734658-8	2003	In the second case, in tumor samples from one hemisphere, nuclear accumulation of p53 was caused by a G--&gt;A transition in codon 244 (Gly--&gt;Asp).	Glycine	136-139	tumor protein p53	Homo sapiens	82-85
12943507-1	2003	Using site-directed mutagenesis and steady-state kinetic measurements, the functional role of the conserved glycine 127 in a human vaccinia H1-related phosphatase (VHR) was investigated.	Glycine	108-115	dual specificity phosphatase 3	Homo sapiens	131-162
12780388-7	2003	Insulin stimulated [14C]Gly-Sar uptake with an ED50 value of 3.5 +/- 2.0 ng mL-1 (n = 3-6) and a maximal stimulation of approximately 18% (n = 3-6).	Glycine	24-27	insulin	Homo sapiens	0-7
12943507-1	2003	Using site-directed mutagenesis and steady-state kinetic measurements, the functional role of the conserved glycine 127 in a human vaccinia H1-related phosphatase (VHR) was investigated.	Glycine	108-115	dual specificity phosphatase 3	Homo sapiens	164-167
12626499-7	2003	Furthermore, the equivalent mutations in the C terminus of rat IGFBP-2 (C-Term 2) also results in a significant reduction in IGF-I binding, suggesting that the highly conserved Gly and Gln residues have a conserved IGF-I binding function in all six IGFBPs.	Glycine	177-180	insulin-like growth factor binding protein 2	Rattus norvegicus	63-70
12826625-5	2003	This protein exhibits significant sequence similarity with the yeast Pho89 protein, which is known to be a Na(+)/Pi co-transporter, although the PTB1 protein carries an additional Gln- and Gly-rich large hydrophilic region in the middle of its primary structure.	Glycine	189-192	uncharacterized protein	Chlamydomonas reinhardtii	145-149
12788385-1	2003	In pressure-overloaded myocardium, our recent study demonstrated cytoskeletal assembly of c-Src and other signaling proteins which was partially mimicked in vitro using adult feline cardiomyocytes embedded in three-dimensional (3D) collagen matrix and stimulated with an integrin-binding Arg-Gly-Asp (RGD) peptide.	Glycine	292-295	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	90-95
12761330-4	2003	The majority of mutations that strongly affected proton sensitivity were clustered in the extracellular end of the second transmembrane domain (M3) and adjacent linker leading to the S2 portion of the glycine-binding domain of NR1.	Glycine	201-208	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	227-230
12626499-7	2003	Furthermore, the equivalent mutations in the C terminus of rat IGFBP-2 (C-Term 2) also results in a significant reduction in IGF-I binding, suggesting that the highly conserved Gly and Gln residues have a conserved IGF-I binding function in all six IGFBPs.	Glycine	177-180	insulin-like growth factor binding protein 2	Rattus norvegicus	249-255
12686158-1	2003	5-Aminolevulinic acid synthase (ALAS), the first enzyme of the heme biosynthesis pathway, catalyses the pyridoxal 5"-phosphate-dependent condensation between glycine and succinyl-CoA to yield 5-aminolevulinic acid (5-amino-4-oxopentanoate).	Glycine	158-165	5'-aminolevulinate synthase 1	Homo sapiens	0-30
12731874-3	2003	Glycine had little effect alone but potentiated the effect of ATP in increasing the resistance to thrombin digestion, consistent with the formation of an enzyme-bound adenylate.	Glycine	0-7	coagulation factor II, thrombin	Homo sapiens	98-106
12817477-1	2003	B8Gly is absolutely conserved in insulin from different species, and in other members of the insulin superfamily the corresponding position is always occupied by a Gly residue.	Glycine	2-5	insulin	Homo sapiens	33-40
12845800-1	2003	The kinetics of the nucleophilic addition reactions of divinyl sulfone to amino groups of glycine and model proteins was studied in aqueous solution at 30 degrees C. The rate constants for glycine, bovine serum albumin, and alpha 1-casein were (4.84 +/- 0.58) x 10(-1), (2.97 +/- 0.31) x 10(-2), and (2.38 +/- 0.49) x 10(-2) M-1s-1, respectively.	Glycine	90-97	albumin	Homo sapiens	205-231
12691588-2	2003	Due to the relatively low thermodynamic stability of [Co(gly)(3)](-), a 1:3 Co(II)/gly stoichiometric solution at physiological pH is approximately a 2:1 mixture of [Co(gly)(2)(H(2)O)(2)] and [Co(gly)(H(2)O)(4)](+).	Glycine	57-60	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	76-82
12691588-6	2003	Line widths at half-height were significantly (p &lt; 0.05) less for Co(II)/gly than for Co(2+)((aq)) at rho values in the range 0.066-0.40.	Glycine	76-79	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	69-75
12729928-1	2003	Mutations of the glycine residue at the amino terminus of HA2 have been shown to have a large effect on the fusion activity of HA2, the extent of which apparently correlates with the side chain bulkiness of the substituting amino acids.	Glycine	17-24	keratin 32	Homo sapiens	58-61
12729928-1	2003	Mutations of the glycine residue at the amino terminus of HA2 have been shown to have a large effect on the fusion activity of HA2, the extent of which apparently correlates with the side chain bulkiness of the substituting amino acids.	Glycine	17-24	keratin 32	Homo sapiens	127-130
12611906-6	2003	All three strains possessed a homozygous guanine-to-thymine transversion in exon 12 of the Abcg5 gene that results in the substitution of a conserved glycine residue for a cysteine amino acid in the extracellular loop between the fifth and sixth membrane-spanning domains of the ATP binding cassette half-transporter, sterolin-1.	Glycine	150-157	ATP binding cassette subfamily G member 5	Rattus norvegicus	91-96
12686158-1	2003	5-Aminolevulinic acid synthase (ALAS), the first enzyme of the heme biosynthesis pathway, catalyses the pyridoxal 5"-phosphate-dependent condensation between glycine and succinyl-CoA to yield 5-aminolevulinic acid (5-amino-4-oxopentanoate).	Glycine	158-165	5'-aminolevulinate synthase 1	Homo sapiens	32-36
12686158-2	2003	A three-dimensional structural model of Rhodobacter spheroides ALAS has been constructed and used to identify amino acid residues at the active site that are likely to be important for the recognition of glycine, the only amino acid substrate.	Glycine	204-211	5'-aminolevulinate synthase 1	Homo sapiens	63-67
12562776-7	2003	Thus, both Arg(440) in IL5 and Gly residues in the conserved segment of TM11 appear to constitute important elements for proper functioning of the putative "pH(i) sensor" of Na(+)/H(+) exchanger 1.	Glycine	31-34	solute carrier family 9 member A1	Homo sapiens	174-196
12644579-0	2003	Mutation of the androgen receptor at amino acid 708 (Gly--&gt;Ala) abolishes partial agonist activity of steroidal antiandrogens.	Glycine	53-56	androgen receptor	Homo sapiens	16-33
12721111-11	2003	Therefore, we replaced the Arg residue at position 1202 of MRP1 with Gly.	Glycine	69-72	ATP binding cassette subfamily B member 1	Homo sapiens	59-63
12639947-6	2003	The results showed that IGF-I could stimulate EVT cell migration in a time- and dose-dependent manner and addition of alphaIR3, Arg-Gly-Asp hexapeptide, and antibody against alpha(v)beta(3) integrin attenuated the IGF-I migratory effect.	Glycine	132-135	insulin like growth factor 1	Homo sapiens	24-29
12676688-5	2003	The S. cerevisiae GLY1 gene encodes threonine aldolase (EC 4.1.2.5), which catalyzes the cleavage of threonine to glycine and acetaldehyde.	Glycine	114-121	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	18-22
12831532-1	2003	GW182 is a mRNA binding protein characterized by 60 repeats of glycine (G):tryptophan (W) motifs and is localized in cytoplasmic structures referred to as GW bodies (GWBs).	Glycine	63-70	trinucleotide repeat containing adaptor 6A	Homo sapiens	0-5
12646253-0	2003	Platelet aggregation by membrane-expressed A1 domains of von Willebrand Factor is dependent on residues Asp 560 and Gly 561.	Glycine	116-119	von Willebrand factor	Homo sapiens	57-78
12684256-5	2003	The glycine-evoked release of [(3)H]D-ASP, but not that of [(3)H]GABA, was significantly more pronounced in SOD1-G93A(+) than in control animals.	Glycine	4-11	superoxide dismutase 1, soluble	Mus musculus	108-112
12723598-6	2003	Sequencing of J19 SCL1 showed that the glycine at position 226 in the Scl1 protein had been replaced by asparatic acid, suggesting that this mutation in the protein, a subunit of proteasomes, may be involved in the morphological change.	Glycine	39-46	proteasome core particle subunit alpha 1	Saccharomyces cerevisiae S288C	18-22
12723598-6	2003	Sequencing of J19 SCL1 showed that the glycine at position 226 in the Scl1 protein had been replaced by asparatic acid, suggesting that this mutation in the protein, a subunit of proteasomes, may be involved in the morphological change.	Glycine	39-46	proteasome core particle subunit alpha 1	Saccharomyces cerevisiae S288C	70-74
12700631-8	2003	Conversely, cells expressing a dominant-negative mutant of Hsp27, in which three serine residues (15, 78 and 82) were replaced by glycine, were hypersensitive to the effects of IFN-gamma and exhibited a typical apoptotic phenotype.	Glycine	130-137	interferon gamma	Homo sapiens	177-186
12631734-3	2003	To address this directly, mutant human proinsulin (Arg/Gly(32):Lys/Thr(64)), which cannot be cleaved by conversion endoproteases, was expressed in primary rat islet cells by recombinant adenovirus.	Glycine	55-58	insulin	Homo sapiens	39-49
12750558-10	2003	In conclusion, we found that dietary glycine is a potent anti-angiogenic agent that can reduce wound healing and tumor growth through reduction of iNOS expression.	Glycine	37-44	nitric oxide synthase 2	Homo sapiens	147-151
12606537-5	2003	However, among nondiabetic Pima Indians (n = 183-201), those with the Gly/Gly genotype had a lower mean insulin secretory response to intravenous and oral glucose and a lower mean rate of lipid oxidation (over 24 h in a respiratory chamber) despite a larger mean subcutaneous abdominal adipocyte size and a higher mean plasma free fatty acid concentration.	Glycine	70-73	insulin	Homo sapiens	104-111
12606537-5	2003	However, among nondiabetic Pima Indians (n = 183-201), those with the Gly/Gly genotype had a lower mean insulin secretory response to intravenous and oral glucose and a lower mean rate of lipid oxidation (over 24 h in a respiratory chamber) despite a larger mean subcutaneous abdominal adipocyte size and a higher mean plasma free fatty acid concentration.	Glycine	74-77	insulin	Homo sapiens	104-111
12541324-4	2003	The L. maderae enzyme cleaved the cockroach peptide LemTRP-1 and the mammalian NEP substrate [DAla(2),Leu(5)]enkephalin at the Gly-Phe peptide bond.	Glycine	127-130	membrane metalloendopeptidase	Homo sapiens	79-82
12646286-0	2003	Protein kinase C epsilon is involved in ethanol potentiation of glycine-gated Cl(-) current in rat neurons of ventral tegmental area.	Glycine	64-71	protein kinase C, epsilon	Rattus norvegicus	0-24
12646286-8	2003	Phorbol-12-myristate-13-acetate (PMA, 10 nM), a PKC activator also increased I(Gly) and reduced ethanol potentiation of I(Gly).	Glycine	79-82	protein kinase C, epsilon	Rattus norvegicus	48-51
12646286-8	2003	Phorbol-12-myristate-13-acetate (PMA, 10 nM), a PKC activator also increased I(Gly) and reduced ethanol potentiation of I(Gly).	Glycine	122-125	protein kinase C, epsilon	Rattus norvegicus	48-51
12646286-10	2003	Thus, ethanol potentiation of I(Gly) may be associated with PKC activation.	Glycine	32-35	protein kinase C, epsilon	Rattus norvegicus	60-63
12565930-1	2003	The synthesis and pharmacological activity of novel nociceptin/orphanin FQ (N/OFQ) analogues modified in the Phe(1)-Gly(2) peptide bond are reported.	Glycine	116-119	prepronociceptin	Homo sapiens	52-62
12466265-3	2003	One of gene products (ORF1) catalyzed the methylation reactions of glycine and sarcosine with S-adenosylmethionine acting as the methyl donor.	Glycine	67-74	ORF1	Homo sapiens	22-26
12466265-10	2003	The changes of amino acids Arg-169 to Lys or Glu in ORF1 and Pro-171 to Gln and/or Met-172 to Arg in ORF2 significantly decreased V(max) and increased K(m) for methyl acceptors (glycine, sarcosine, and dimethylglycine) but modestly affected K(m) for S-adenosylmethionine, indicating the importance of these amino acids for the binding of methyl acceptors.	Glycine	178-185	ORF1	Homo sapiens	52-56
12573244-8	2003	Both the Arg and Gly are absolutely conserved, not only in all known Bbeta chains, but also in all homologous alphaE and gamma chains and in all fibrinogen-related proteins.	Glycine	17-20	fibrinogen beta chain	Homo sapiens	145-155
12426310-6	2003	Mutational studies revealed that Gly(122) and His(123) are crucial for binding to SUFU, suggesting the importance of hydrophobicity for the correct binding conformation.	Glycine	33-36	SUFU negative regulator of hedgehog signaling	Homo sapiens	82-86
12565930-1	2003	The synthesis and pharmacological activity of novel nociceptin/orphanin FQ (N/OFQ) analogues modified in the Phe(1)-Gly(2) peptide bond are reported.	Glycine	116-119	prepronociceptin	Homo sapiens	63-74
12565930-1	2003	The synthesis and pharmacological activity of novel nociceptin/orphanin FQ (N/OFQ) analogues modified in the Phe(1)-Gly(2) peptide bond are reported.	Glycine	116-119	prepronociceptin	Homo sapiens	76-81
12539241-1	2003	In vertebrates, members of the cysteine-rich protein (CRP) family are characterized by the presence of two LIM domains linked to short glycine-rich repeats.	Glycine	135-142	C-reactive protein	Homo sapiens	31-52
12539241-1	2003	In vertebrates, members of the cysteine-rich protein (CRP) family are characterized by the presence of two LIM domains linked to short glycine-rich repeats.	Glycine	135-142	C-reactive protein	Homo sapiens	54-57
12598410-9	2003	The VIP-induced inhibition of Gly-Sar uptake is abolished in the presence of the protein kinase A (PKA) inhibitor H-89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide.2HCl).	Glycine	30-33	vasoactive intestinal peptide	Homo sapiens	4-7
12568815-5	2003	When comparing with human Hb alpha-chain, alterations in important regions can be noted: alpha110 Ala-Gly, alpha114 Pro-Gly, alpha117 Phe-Tyr and alpha122 His-Gln.	Glycine	102-105	Fc gamma receptor and transporter	Homo sapiens	29-40
12615358-6	2003	The unique mutations in the glycine-rich domain of the mutant loricrin form arginine-rich nuclear localization sequences (NLSs) that disrupt differentiation of keratinocytes.	Glycine	28-35	loricrin cornified envelope precursor protein	Homo sapiens	62-70
12558979-1	2003	The GLYT1 subtypes of glycine transporter are expressed in glia surrounding excitatory synapses in the mammalian CNS and may regulate synaptic glycine concentrations required for activation of the NMDA subtypes of glutamate receptor.	Glycine	22-29	solute carrier family 6 member 9	Homo sapiens	4-9
12558979-2	2003	In this report we demonstrate that the rate of glycine transport by GLYT1 is inhibited by arachidonic acid.	Glycine	47-54	solute carrier family 6 member 9	Homo sapiens	68-73
18924618-4	2003	With a new procedure getting high purified fibrinogen by glycine precipitation, the calibrator determined by both the Clauss and Jacobson methods produced a fibrinogen concentration of 2.20 g l(-1).	Glycine	57-64	fibrinogen beta chain	Homo sapiens	43-53
12414796-0	2003	Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human glutathione transferase p1-1.	Glycine	16-23	S100 calcium binding protein A10	Homo sapiens	125-129
12414796-1	2003	In human glutathione transferase P1-1 (hGSTP1-1) position 146 is occupied by a glycine residue, which is located in a bend of a long loop that together with the alpha6-helix forms a substructure (GST motif II) maintained in all soluble GSTs.	Glycine	79-86	hematopoietic prostaglandin D synthase	Homo sapiens	236-240
12414796-7	2003	Gly-146 is part of the buried local sequence GXXh(T/S)XXDh (X is any residue and h is a hydrophobic residue), conserved in all GSTs and related proteins that seems to behave as a characteristic structural module important for protein folding and stability.	Glycine	0-3	hematopoietic prostaglandin D synthase	Homo sapiens	127-131
15618721-1	2003	The effects of the substitution of glycine at position 42 with various other amino acid residues on the functions of CYP2D6 were studied using debrisoquine (DB) and bunitrolol (BTL) 4-hydroxylations as indices of drug-metabolizing enzymes.	Glycine	35-42	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	117-123
15618735-1	2003	Hitherto three variant forms of ABCG2 have been documented on the basis of their amino acid moieties (i.e., Arg, Gly, and Thr) at the position 482.	Glycine	113-116	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	32-37
12566983-5	2003	Other amino acid transport systems capable of carrying small amounts of glycine are ASC, asc and system L. In addition, an ATP-dependent transport process exists that takes up glycine into synaptic vesicles at nerve endings.	Glycine	72-79	PYD and CARD domain containing	Homo sapiens	84-87
12566983-5	2003	Other amino acid transport systems capable of carrying small amounts of glycine are ASC, asc and system L. In addition, an ATP-dependent transport process exists that takes up glycine into synaptic vesicles at nerve endings.	Glycine	72-79	PYD and CARD domain containing	Homo sapiens	89-92
12566983-5	2003	Other amino acid transport systems capable of carrying small amounts of glycine are ASC, asc and system L. In addition, an ATP-dependent transport process exists that takes up glycine into synaptic vesicles at nerve endings.	Glycine	176-183	PYD and CARD domain containing	Homo sapiens	84-87
12566983-5	2003	Other amino acid transport systems capable of carrying small amounts of glycine are ASC, asc and system L. In addition, an ATP-dependent transport process exists that takes up glycine into synaptic vesicles at nerve endings.	Glycine	176-183	PYD and CARD domain containing	Homo sapiens	89-92
14515016-17	2003	Four micromol Thromstop (BNas-Gly-(pAM)Phe-Pip) delayed force development by greater than 800 s and PCF at 1200 s was reduced by 70%.	Glycine	30-33	prolactin induced protein	Homo sapiens	43-46
15618735-6	2003	The ATPase activity of the plasma membrane expressing ABCG2 (Gly-482) was significantly enhanced by prazosin.	Glycine	61-64	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	54-59
15618735-7	2003	In contrast, ABCG2 (Arg-482) transports [(3)H]methotrexate in an ATP-dependent manner; however, no transport activity was observed with the other variants (Gly-482 and Thr-482).	Glycine	156-159	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	13-18
18924618-4	2003	With a new procedure getting high purified fibrinogen by glycine precipitation, the calibrator determined by both the Clauss and Jacobson methods produced a fibrinogen concentration of 2.20 g l(-1).	Glycine	57-64	fibrinogen beta chain	Homo sapiens	157-167
18924717-6	2003	Purified fibrinogen was prepared using Cohn fraction 1 and glycine precipitation.	Glycine	59-66	fibrinogen beta chain	Homo sapiens	9-19
12525257-10	2003	These data indicate that substitution of the penultimate Ala2 in GIP by Gly or Ser confers resistance to plasma DPP IV degradation, resulting in enhanced biological activity, therefore raising the possibility of their use in the treatment of type 2 diabetes.	Glycine	72-75	gastric inhibitory polypeptide	Homo sapiens	65-68
12524661-5	2003	In addition, stimulation of HAECs with gly-ox-HDL for 48 hours elicited a marked downregulation of catalase and Cu(2+), Zn(2+)-superoxide dismutase (CuZn-SOD), suggesting H(2)O(2) formation by gly-ox-HDL to be due to a disturbance involving oxidant and antioxidant enzymes in the cells.	Glycine	39-42	catalase	Homo sapiens	99-107
12525257-3	2003	Therefore, this study examined the plasma stability, biological activity and antidiabetic potential of two novel NH2-terminal Ala2-substituted analogues of GIP, containing glycine (Gly) or serine (Ser).	Glycine	172-179	gastric inhibitory polypeptide	Homo sapiens	156-159
12524661-6	2003	Treatment of HAECs with gly-ox-HDL attenuated the expression of endothelial nitric oxide synthase (eNOS), but not inducible nitric oxide synthase (iNOS), and this was followed by decreased production of nitric oxide (NO) by the cells.	Glycine	24-27	nitric oxide synthase 3	Homo sapiens	64-97
12191993-4	2002	The reaction of glycine with ALAS follows a three-step kinetic process, ascribed to the formation of the Michaelis complex and the pyridoxal 5"-phosphate-glycine aldimine, followed by the abstraction of the glycine pro-R proton from the external aldimine.	Glycine	16-23	5'-aminolevulinate synthase 1	Homo sapiens	29-33
12482991-4	2003	Serine 927 resides in a conserved motif (Asp-Ser(927)-Gly-Val-Glu-Thr-Ser(932)) homologous to the IKK target sequence in IkappaBalpha.	Glycine	54-57	NFKB inhibitor alpha	Homo sapiens	121-133
12518232-6	2003	Therefore, the ER sites for Miy C and Kob A may be located at Glu(353), Arg(394), Met(517) and Gly(521).	Glycine	95-98	estrogen receptor 1	Homo sapiens	15-17
12450897-9	2002	The serum insulin concentration also was slightly elevated after the ingestion of glycine alone.	Glycine	82-89	insulin	Homo sapiens	10-17
12450897-11	2002	The dynamics of the insulin response after the ingestion of glycine plus glucose were modestly different from those after the ingestion of glucose alone, but the area response was not significantly different.	Glycine	60-67	insulin	Homo sapiens	20-27
12450897-12	2002	CONCLUSION: The data are compatible with the hypothesis that oral glycine stimulates the secretion of a gut hormone that potentiates the effect of insulin on glucose removal from the circulation.	Glycine	66-73	insulin	Homo sapiens	147-154
12472887-5	2002	PC2-null mice displayed a nine-fold increase of cerebral proCCK concentrations, and a two-fold increase in the concentrations of the processing-intermediate, glycine-extended CCK, whereas the concentrations of transmitter-active (i.e. alpha-amidated and O-sulfated) CCK peptides were reduced (61%).	Glycine	158-165	proprotein convertase subtilisin/kexin type 2	Mus musculus	0-3
12191993-2	2002	5-Aminolevulinate synthase is a dimeric protein having an ordered kinetic mechanism with glycine binding before succinyl-CoA and with aminolevulinate release after CoA and carbon dioxide.	Glycine	89-96	5'-aminolevulinate synthase 1	Homo sapiens	0-26
12699776-0	2003	Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY(93)--&gt;ALA) mutation.	Glycine	122-125	superoxide dismutase 1	Homo sapiens	94-120
12493838-2	2003	The replacement of a solvent-exposed lysine residue with glycine (Lys8Gly) in a helix of recombinant cytochrome c does not perturb the native structure, but it entropically potentiates main-chain flexibility and thus can promote local distortional motions and large-scale unfolding.	Glycine	57-64	cytochrome c, somatic	Homo sapiens	101-113
12509629-0	2003	Autoantibodies to dsDNA cross-react with the arginine-glycine-rich domain of heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) and promote methylation of hnRNP A2.	Glycine	54-61	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	77-119
12509629-0	2003	Autoantibodies to dsDNA cross-react with the arginine-glycine-rich domain of heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) and promote methylation of hnRNP A2.	Glycine	54-61	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	121-129
12509629-5	2003	The arginine-glycine-rich domain in hnRNP A2 was found to be the reaction site, and the methylation of hnRNP A2 by PRMT1 (protein arginine methyltransferase 1) was increased by anti-DNA.	Glycine	13-20	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	36-44
12509629-5	2003	The arginine-glycine-rich domain in hnRNP A2 was found to be the reaction site, and the methylation of hnRNP A2 by PRMT1 (protein arginine methyltransferase 1) was increased by anti-DNA.	Glycine	13-20	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	103-111
12480177-9	2002	Hence, glycine residues of the GXXXRXG motif are important determinants of NET expression and function, while the arginine residue does not have a major role.	Glycine	7-14	solute carrier family 6 member 2	Homo sapiens	75-78
12446775-5	2002	In support of the hypothesis that an interaction between eRF1 and uORF2 contributes to uORF2 inhibitory activity, specific residues in each protein, glycines 183 and 184 of the eRF1 GGQ motif and prolines 21 and 22 of the uORF2 peptide, were found to be necessary for full inhibition of downstream translation.	Glycine	149-157	eukaryotic translation termination factor 1	Homo sapiens	57-61
12324470-7	2002	Among these sequences, Gln(199)-Ala(203), Leu(225)-Leu(230), and Gly(305)-His(309) are important for the binding of both ligands, whereas Arg(144)-Lys(148) is more critical for fibrinogen than for C3bi binding.	Glycine	65-68	fibrinogen beta chain	Homo sapiens	177-187
12191993-4	2002	The reaction of glycine with ALAS follows a three-step kinetic process, ascribed to the formation of the Michaelis complex and the pyridoxal 5"-phosphate-glycine aldimine, followed by the abstraction of the glycine pro-R proton from the external aldimine.	Glycine	154-161	5'-aminolevulinate synthase 1	Homo sapiens	29-33
12191993-5	2002	Significantly, the rate associated with this third step (k(3) = 0.002 s(-1)) is consistent with the rate determined for the ALAS-catalyzed removal of tritium from [2-(3)H(2)]glycine.	Glycine	174-181	5'-aminolevulinate synthase 1	Homo sapiens	124-128
12215427-6	2002	Deletion of the Gly-76 residue in the carboxyl terminus of Nedd8 abolished this effect and prevented AhR-Nedd8 interaction.	Glycine	16-19	aryl-hydrocarbon receptor	Mus musculus	101-104
12417259-2	2002	DMSO caused a concentration-dependent 10-fold stimulation of hNMT activity in the presence of a pp60(src)-derived peptide substrate (Gly-Ser-Ser-Lys-Ser-Lys-Pro-Lys-Arg).	Glycine	133-136	N-myristoyltransferase 1	Homo sapiens	61-65
12417259-2	2002	DMSO caused a concentration-dependent 10-fold stimulation of hNMT activity in the presence of a pp60(src)-derived peptide substrate (Gly-Ser-Ser-Lys-Ser-Lys-Pro-Lys-Arg).	Glycine	133-136	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	101-104
12417259-5	2002	When a MARCKS (myristoylated alanine-rich C-kinase substrate)-derived peptide substrate (Gly-Ala-Gln-Phe-Ser-Lys-Thr-Ala-Arg-Arg) and the M2 gene segment of the reovirus type 3 peptide substrate (Gly-Asn-Ala-Ser-Ser-Ile-Lys-Lys-Lys) were used, hNMT activity was increased by approximately 8.5- and 7-fold, respectively.	Glycine	89-92	N-myristoyltransferase 1	Homo sapiens	244-248
12417265-1	2002	We previously found that human chymase cleaves big endothelins (ETs) at the Tyr(31)-Gly(32) bond and produces 31-amino acid ETs (1-31), without any further degradation products.	Glycine	84-87	chymase 1	Homo sapiens	31-38
12417265-1	2002	We previously found that human chymase cleaves big endothelins (ETs) at the Tyr(31)-Gly(32) bond and produces 31-amino acid ETs (1-31), without any further degradation products.	Glycine	84-87	endothelin 1	Homo sapiens	51-62
12401724-6	2002	Moreover, gly-LDL triggered src but not JAK2 kinase activity.	Glycine	10-13	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	28-31
12376561-6	2002	The actions of IGFBP-3 and -5 on cell attachment to ECM were lost in the presence of a soluble Arg-Gly-Asp (RGD)-containing fibronectin fragment.	Glycine	99-102	fibronectin 1	Homo sapiens	124-135
12376566-5	2002	These data demonstrate that thrombospondin-1-induced cell chemotaxis can be inhibited by a peptide containing the Arg-Gly-Asp motif, a function-blocking alpha(v)beta(3) antibody, a function-blocking integrin-associated protein (IAP) antibody and pertussis toxin, while thrombospondin-1-stimulated DNA synthesis is inhibited by a function-blocking alpha(3)beta(1) antibody.	Glycine	118-121	thrombospondin 1	Homo sapiens	28-44
12196530-7	2002	Introduction of multiple glycine substitutions into the N-terminal segment of the A chain (residues A1-A5) yields analogs that are less stable than native insulin and essentially without biological activity.	Glycine	25-32	insulin	Homo sapiens	155-162
12373782-12	2002	The glycine-IR population consists mainly of AII amacrine cell types, but clearly another non-AII type is involved.	Glycine	4-11	NLR family pyrin domain containing 3	Homo sapiens	45-48
12373782-13	2002	The non-AII glycine-IR population resembles a small- to medium-field diffuse type.	Glycine	12-19	NLR family pyrin domain containing 3	Homo sapiens	8-11
12133828-11	2002	The data obtained from 14 new chimeras sustained that two nonadjacent pairs of amino acids, Gln(135) Thr(136) and Gly(140) Ser(141) in the C-terminal end of the N-terminal VPAC1 receptor ectodomain constitute a selective filter that strongly restricts access of secretin to the VPAC1 receptor.	Glycine	114-117	vasoactive intestinal peptide receptor 1	Homo sapiens	172-186
12856309-10	2002	We found that two signature candidate sites (Gly 174, Asn 175--human cathepsin L numbering) for cathepsin L-like group are conserved in PwCP5, which are conserved within cathepsin L-like group and also different from those of cruzipain and other cysteine proteinase groups.	Glycine	45-48	cathepsin L	Homo sapiens	69-80
12856309-10	2002	We found that two signature candidate sites (Gly 174, Asn 175--human cathepsin L numbering) for cathepsin L-like group are conserved in PwCP5, which are conserved within cathepsin L-like group and also different from those of cruzipain and other cysteine proteinase groups.	Glycine	45-48	cathepsin L	Homo sapiens	96-107
12856309-10	2002	We found that two signature candidate sites (Gly 174, Asn 175--human cathepsin L numbering) for cathepsin L-like group are conserved in PwCP5, which are conserved within cathepsin L-like group and also different from those of cruzipain and other cysteine proteinase groups.	Glycine	45-48	cathepsin L	Homo sapiens	96-107
12417033-6	2002	Among these putative protein methylacceptors, three are heterogeneous nuclear ribonucleoproteins (hnRNPA2/B1 and hnRNP K) that are reportedly methylated in their arginine- and glycine-rich RGG motifs.	Glycine	176-183	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	98-108
12355415-6	2002	On the other hand, an analysis of neurons colabeled for both GABA and glycine, revealed that this specific colabeling increased in the Lurcher mutant (by 40%).	Glycine	70-77	glutamate receptor, ionotropic, delta 2	Mus musculus	135-142
12355415-9	2002	In summary, the increase in the number of neurons colabeled for GABA and glycine, together with the increase in the size of the inhibitory synaptic boutons, could help in providing the minimum inhibition needed to maintain a residual "cerebellar" functionality in the Lurcher DCN.	Glycine	73-80	glutamate receptor, ionotropic, delta 2	Mus musculus	268-275
12402351-8	2002	The L237M substitution was predicted as most likely to alter protein function, whereas the glycine at position 230 may be specific to COX1 function.	Glycine	91-98	prostaglandin-endoperoxide synthase 1	Homo sapiens	134-138
12133828-11	2002	The data obtained from 14 new chimeras sustained that two nonadjacent pairs of amino acids, Gln(135) Thr(136) and Gly(140) Ser(141) in the C-terminal end of the N-terminal VPAC1 receptor ectodomain constitute a selective filter that strongly restricts access of secretin to the VPAC1 receptor.	Glycine	114-117	vasoactive intestinal peptide receptor 1	Homo sapiens	278-292
12138088-7	2002	Cys(60) and Gly(61) are essential for Grx5 function, whereas other single or double substitutions in the same region had no phenotypic effects.	Glycine	12-15	monothiol glutaredoxin GRX5	Saccharomyces cerevisiae S288C	38-42
12151404-6	2002	A 2-hydroxyethyl adduct was found by mass spectrometry to be present in the Gly(136)-Arg(147) peptide from tryptic digests of AGT reacted with DBE.	Glycine	76-79	angiotensinogen	Homo sapiens	126-129
12138088-8	2002	Gly(115) and Gly(116) could be important for the formation of a glutathione cleft on the Grx5 surface, in contrast to adjacent Cys(117).	Glycine	0-3	monothiol glutaredoxin GRX5	Saccharomyces cerevisiae S288C	89-93
12138088-8	2002	Gly(115) and Gly(116) could be important for the formation of a glutathione cleft on the Grx5 surface, in contrast to adjacent Cys(117).	Glycine	13-16	monothiol glutaredoxin GRX5	Saccharomyces cerevisiae S288C	89-93
12379490-14	2002	These studies postulate that an arginine-glycine-aspartic acid sequence found on mouse GHBP but absent in other species is responsible for the association of GHBP with the plasma membrane by binding to one or more integrins on the surface of liver cells.	Glycine	41-48	growth hormone receptor	Mus musculus	87-91
12243756-4	2002	HnRNP A2 is composed of two sequential RNA binding domains (RBDI and RBDII), a glycine-rich domain, and a nuclear import domain (M9).	Glycine	79-86	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	0-8
12379490-14	2002	These studies postulate that an arginine-glycine-aspartic acid sequence found on mouse GHBP but absent in other species is responsible for the association of GHBP with the plasma membrane by binding to one or more integrins on the surface of liver cells.	Glycine	41-48	growth hormone receptor	Mus musculus	158-162
12215525-5	2002	However, prenatal and neonatal mortalities are significantly increased in Gcn2(-/-) mice whose mothers were reared on leucine-, tryptophan-, or glycine-deficient diets during gestation.	Glycine	144-151	eukaryotic translation initiation factor 2 alpha kinase 4	Mus musculus	74-78
12406575-1	2002	JKTBP proteins consisting of two canonical RNA binding domains (RBDs) and a glycine-rich carboxyl domain are nucleocytoplasmic shuttling proteins.	Glycine	76-83	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	0-5
12195119-11	2002	In the younger subjects ( 60 years old) with low plasma renin activity (&lt; 1.0 ng/ml per h), however, ambulatory BP and home BP were significantly higher in the subjects with the Gly/Trp or Trp/Trp genotypes of ADD-1 polymorphism than in those with the Gly/Gly genotype.	Glycine	181-184	renin	Homo sapiens	56-61
12027806-6	2002	A similar cleavage sequence (Phe-Arg-Pro-Gly downward arrow Ser-Val-Val-Val, where downward arrow signifies the cleavage site) has been reported in human MUC1 and analogous sites are present in human MUC3, MUC12 and MUC17.	Glycine	41-44	MUC3	Homo sapiens	200-204
12194921-4	2002	RESULTS: Western blot analyses with NH(2)-terminus-truncated L-PGDS mapped the epitopes to Ala(23)-Val(28) (MAb-7F5 and -10A3), Ser(52)-Ala(73) (MAb-9A6), Tyr(107)-Val(120) (MAb-1B7 and -6F5), and Gly(140)-Pro(155) (MAb-6B9).	Glycine	197-200	prostaglandin D2 synthase	Homo sapiens	61-67
12383231-8	2002	Electrophysiological analysis of heterologously expressed glycine transporters (GlyT) revealed for GlyT2 zero, and for GlyT1 a modest (&lt; 20%), reduction of glycine uptake in the presence of 5 micro m Zn2+, indicating that prolongation of glycinergic IPSCs by Zn2+ is not due to inhibition of glycine removal from the synaptic cleft.	Glycine	58-65	solute carrier family 6 member 9	Homo sapiens	119-124
12383231-8	2002	Electrophysiological analysis of heterologously expressed glycine transporters (GlyT) revealed for GlyT2 zero, and for GlyT1 a modest (&lt; 20%), reduction of glycine uptake in the presence of 5 micro m Zn2+, indicating that prolongation of glycinergic IPSCs by Zn2+ is not due to inhibition of glycine removal from the synaptic cleft.	Glycine	159-166	solute carrier family 6 member 9	Homo sapiens	119-124
12127561-9	2002	Sequencing of the TP53 gene revealed a mutation (codon 147(valine--&gt;glycine)) in exon 5.	Glycine	71-78	tumor protein p53	Homo sapiens	18-22
12187102-10	2002	The IL-6 treated rats showed a significant increase in tubular cell proliferation in cortex and medulla, as well as in the expression of c-met protein in the renal cortex, compared to untreated Gly-ARF rats.	Glycine	194-197	interleukin 6	Rattus norvegicus	4-8
12916152-11	2002	The essential effect on thrombin has been found from the side of 1% glycin, 0.5% PEG, 1% saccharose and so on.	Glycine	68-74	coagulation factor II, thrombin	Homo sapiens	24-32
12169665-5	2002	ARTEMIS consists of three distinct modules: an N-terminal receptor-like region, a centrally positioned glycine-rich stretch containing a nucleoside triphosphate-binding site, and a C-terminal YidC/Oxa1p/Alb3 protein translocase-like domain.	Glycine	103-110	OxaA/YidC-like membrane insertion protein	Arabidopsis thaliana	0-7
12187102-12	2002	DISCUSSION: IL-6 stimulates tubular regeneration after Gly-ARF and increases the expression of c-met in the renal cortex.	Glycine	55-58	interleukin 6	Rattus norvegicus	12-16
12446930-5	2002	In the present work, QM/MM and Amber calculations reveal that self assembly of antiparallel beta-sheet which brings Met35 into the required close proximity to a glycine residue is more likely if the residue is Gly29 or Gly33, than any of the other four glycine residues of Abeta.	Glycine	161-168	amyloid beta precursor protein	Homo sapiens	273-278
12430915-10	2002	We have found six cases of point mutations of vWF gene, Ala737--&gt;Glu, Gly 22--&gt;Glu, Met37 Val and Ser71--&gt;stop codon.	Glycine	73-76	von Willebrand factor	Homo sapiens	46-49
12446930-5	2002	In the present work, QM/MM and Amber calculations reveal that self assembly of antiparallel beta-sheet which brings Met35 into the required close proximity to a glycine residue is more likely if the residue is Gly29 or Gly33, than any of the other four glycine residues of Abeta.	Glycine	253-260	amyloid beta precursor protein	Homo sapiens	273-278
12186269-4	2002	Glycine levels in brain are regulated by GLYT1-type glycine transporters.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	41-46
12124437-2	2002	Multiprobe ribonuclease protection assays (RPAs) were used to investigate expression of 36 different cytokines and apoptosis-related genes in spinal cords of mice that ubiquitously express human SOD1 bearing a glycine (r) alanine substitution at residue 93 (G93A-SOD1).	Glycine	210-217	superoxide dismutase 1	Homo sapiens	195-199
12065750-4	2002	The different amino acid sequence that forms helix 3 in rhodopsin (basically the conserved Gly(3.36)Glu(3.37) motif in the opsin family) and the 5-HT1A receptor (the conserved Cys(3.36)Thr(3.37) motif in the neurotransmitter family) produces these structural divergences.	Glycine	91-94	rhodopsin	Homo sapiens	56-65
12093444-10	2002	RESULTS: The results showed that interleukin-1beta and tumor necrosis factor-alpha concentrations in peritoneal lavage fluid at 6 h and interleukin-6 levels at 24 h after CLP in the Gly group were significantly higher than those in the Arg group.	Glycine	182-185	interleukin 1 beta	Rattus norvegicus	33-82
12093444-10	2002	RESULTS: The results showed that interleukin-1beta and tumor necrosis factor-alpha concentrations in peritoneal lavage fluid at 6 h and interleukin-6 levels at 24 h after CLP in the Gly group were significantly higher than those in the Arg group.	Glycine	182-185	interleukin 6	Rattus norvegicus	136-149
12052894-2	2002	Alignment of the HIC1 and HRG22 proteins from various species highlighted a perfectly conserved GLDLSKK/R motif highly related to the consensus CtBP interaction motif (PXDLSXK/R), except for the replacement of the virtually invariant proline by a glycine.	Glycine	247-254	HIC ZBTB transcriptional repressor 2	Homo sapiens	26-31
12180535-1	2002	PURPOSE: Systemic and hepato-biliary clearance of peptidomimetic thrombin inhibitors of the 4-amidinophenylalanine amide-type, derived from NAPAP (Nalpha-[2-naphthylsulfonyl-glycyl]-4-amidinophenylalanine-piperidide) by substituting Gly in P2 for natural and unnatural amino acids or by varying the C- and N-terminal moieties.	Glycine	233-236	coagulation factor II	Rattus norvegicus	65-73
12135567-1	2002	A novel human TF-1 cell apoptosis-related protein, TFAR19, cloned from a human leukemia cell line, TF-1, was first overexpressed in Escherichia coli with the sequence Met-Gly-His(6)-Gly-Thr-Asn-Gly, a hexahistidine sequence followed by a hydroxylamine cleavage site attached to its amino terminus.	Glycine	171-174	programmed cell death 5	Homo sapiens	51-57
12037013-5	2002	RESULTS: The N-terminal Met-Gly-Cys-X-Phe-Ser-Lys motif of human RP2 is necessary and sufficient for the protein"s plasma membrane localization.	Glycine	28-31	RP2 activator of ARL3 GTPase	Homo sapiens	65-68
12173071-2	2002	The mutation results in an exchange of aspartic acid into a glycine of the amino acid 294 of PKCalpha, which is located adjacent to the Ca (2+)-binding hinge region and has been proposed as an activation inhibitor.	Glycine	60-67	protein kinase C alpha	Homo sapiens	93-101
12068077-2	2002	The inhibition constants (K (I) s) for the binding of l-glutamate and glycine to NR1-1a/NR2A determined by [3 H]CGP 39653 and [3 H]MDL 105 519 displacement assays, respectively, were not significantly different between NR1-1a/NR2A receptors coexpressed +/- PSD-95(c-Myc).	Glycine	70-77	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	81-84
12068077-2	2002	The inhibition constants (K (I) s) for the binding of l-glutamate and glycine to NR1-1a/NR2A determined by [3 H]CGP 39653 and [3 H]MDL 105 519 displacement assays, respectively, were not significantly different between NR1-1a/NR2A receptors coexpressed +/- PSD-95(c-Myc).	Glycine	70-77	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	88-92
12068077-1	2002	Coexpression of PSD-95(c-Myc) with NR1-1a/NR2A NMDA receptors in human embryonic kidney (HEK) 293 cells resulted in a decrease in efficacy for the glycine stimulation of [3 H]MK801 binding similar to that previously described for l-glutamate.	Glycine	147-154	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	35-38
12068077-1	2002	Coexpression of PSD-95(c-Myc) with NR1-1a/NR2A NMDA receptors in human embryonic kidney (HEK) 293 cells resulted in a decrease in efficacy for the glycine stimulation of [3 H]MK801 binding similar to that previously described for l-glutamate.	Glycine	147-154	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	42-46
12068077-2	2002	The inhibition constants (K (I) s) for the binding of l-glutamate and glycine to NR1-1a/NR2A determined by [3 H]CGP 39653 and [3 H]MDL 105 519 displacement assays, respectively, were not significantly different between NR1-1a/NR2A receptors coexpressed +/- PSD-95(c-Myc).	Glycine	70-77	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	219-222
12068077-2	2002	The inhibition constants (K (I) s) for the binding of l-glutamate and glycine to NR1-1a/NR2A determined by [3 H]CGP 39653 and [3 H]MDL 105 519 displacement assays, respectively, were not significantly different between NR1-1a/NR2A receptors coexpressed +/- PSD-95(c-Myc).	Glycine	70-77	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	226-230
12113672-0	2002	[Effect of glycine on the expression of CD(14) gene and protein of hepatic tissue in the course of developing cirrhosis of rats].	Glycine	11-18	CD14 molecule	Rattus norvegicus	40-46
12134953-6	2002	The substrate specificity of Arg-Gly and Arg-Gly-Asp was determined using purified inducible NO synthase (iNOS).	Glycine	33-36	nitric oxide synthase 2	Rattus norvegicus	83-104
12134953-6	2002	The substrate specificity of Arg-Gly and Arg-Gly-Asp was determined using purified inducible NO synthase (iNOS).	Glycine	33-36	nitric oxide synthase 2	Rattus norvegicus	106-110
12134953-12	2002	Arg-Gly and Arg-Gly-Asp were found to be direct substrates for iNOS with similar Km and Vmax values to those of Arg.	Glycine	4-7	nitric oxide synthase 2	Rattus norvegicus	63-67
12134953-12	2002	Arg-Gly and Arg-Gly-Asp were found to be direct substrates for iNOS with similar Km and Vmax values to those of Arg.	Glycine	16-19	nitric oxide synthase 2	Rattus norvegicus	63-67
12113672-1	2002	OBJECTIVE: To observe the effect of glycine on the expression of CD(14) mRNA and protein of hepatic tissue in the course of developing cirrhosis of rats.	Glycine	36-43	CD14 molecule	Rattus norvegicus	65-71
12113672-5	2002	RESULTS: The expression of CD(14) mRNA and CD(14) protein in the hepatic tissue of fatty liver and cirrhotic rats fed with diets containing glycine was weaker than their control groups, and the expression of CD(14) mRNA and protein was the weakest in 8 weeks cirrhotic rats fed with the diets.	Glycine	140-147	CD14 molecule	Rattus norvegicus	27-33
12113672-5	2002	RESULTS: The expression of CD(14) mRNA and CD(14) protein in the hepatic tissue of fatty liver and cirrhotic rats fed with diets containing glycine was weaker than their control groups, and the expression of CD(14) mRNA and protein was the weakest in 8 weeks cirrhotic rats fed with the diets.	Glycine	140-147	CD14 molecule	Rattus norvegicus	43-49
12113672-5	2002	RESULTS: The expression of CD(14) mRNA and CD(14) protein in the hepatic tissue of fatty liver and cirrhotic rats fed with diets containing glycine was weaker than their control groups, and the expression of CD(14) mRNA and protein was the weakest in 8 weeks cirrhotic rats fed with the diets.	Glycine	140-147	CD14 molecule	Rattus norvegicus	43-49
12113672-6	2002	CONCLUSIONS: Glycine can markedly downregulate the expression of CD(14) mRNA and CD(14) protein in hepatic tissues of cirrhotic rats.	Glycine	13-20	CD14 molecule	Rattus norvegicus	65-71
12113672-6	2002	CONCLUSIONS: Glycine can markedly downregulate the expression of CD(14) mRNA and CD(14) protein in hepatic tissues of cirrhotic rats.	Glycine	13-20	CD14 molecule	Rattus norvegicus	81-87
11960773-2	2002	It is presumed that progastrin is cleaved at pairs of basic amino acids by a prohormone convertase to form a glycine-extended intermediate (G-Gly) that serves as a substrate for peptidyl-glycine alpha-amidating monooxygenase (PAM), resulting in COOH-terminally amidated gastrin.	Glycine	109-116	peptidylglycine alpha-amidating monooxygenase	Canis lupus familiaris	178-224
12054676-3	2002	The novel splice variant encodes a protein (cGK II Delta(441-469)) lacking 29 amino acids of the cGK II Mg-ATP-binding/catalytic domain, including the conserved glycine-rich loop consensus motif Gly-x-Gly-x-x-Gly-x-Val which interacts with ATP in the protein kinase family of enzymes.	Glycine	161-168	protein kinase cGMP-dependent 2	Homo sapiens	44-50
11960773-2	2002	It is presumed that progastrin is cleaved at pairs of basic amino acids by a prohormone convertase to form a glycine-extended intermediate (G-Gly) that serves as a substrate for peptidyl-glycine alpha-amidating monooxygenase (PAM), resulting in COOH-terminally amidated gastrin.	Glycine	109-116	peptidylglycine alpha-amidating monooxygenase	Canis lupus familiaris	226-229
11960773-2	2002	It is presumed that progastrin is cleaved at pairs of basic amino acids by a prohormone convertase to form a glycine-extended intermediate (G-Gly) that serves as a substrate for peptidyl-glycine alpha-amidating monooxygenase (PAM), resulting in COOH-terminally amidated gastrin.	Glycine	109-116	gastrin	Canis lupus familiaris	23-30
11961270-2	2002	A long chimeric receptor, CD46CD[55-46], was generated from the CD46 backbone, encompassing the four short consensus repeat (SCR) domains of CD46 linked via a flexible glycine hinge to SCR1 and SCR2 of CD55, SCR3 and SCR4 of CD46 and the STP, transmembrane and cytoplasmic tail of CD46.	Glycine	168-175	CD46 molecule	Homo sapiens	26-30
12107756-6	2002	There were significant differences in fasting insulin (Gly/Gly; 37.7 +/- 1.43, Gly/Ser; 40.2 +/- 1.21, Ser/Ser; 44.3 +/- 1.82 pmol/l, p = 0.018) and insulin resistance index (Gly/Gly; 1.48 +/- 0.06, Gly/Ser; 1.56 +/- 0.05, Ser/Ser; 1.75 +/- 0.08, p = 0.027) according to the genotype of the Gly482Ser polymorphism.	Glycine	55-58	insulin	Homo sapiens	46-53
12009947-1	2002	Three amino acids residues, Arg-Gly-Asp (RGD), in vitronectin and fibronectin show affinity for alpha(V)beta(3) integrins expressed in vascular endothelial cells.	Glycine	32-35	fibronectin 1	Homo sapiens	66-77
12009949-3	2002	The Gly-Sar uptake via hPEPT1 was significantly inhibited in the polyrotaxane conjugates, and this inhibitory effect was not explained by the sum of interaction between hPEPT1 and alpha-CD-Val-Lys conjugates.	Glycine	4-7	solute carrier family 15 member 1	Homo sapiens	23-29
11978638-0	2002	Insulin secretory function is impaired in isolated human islets carrying the Gly(972)--&gt;Arg IRS-1 polymorphism.	Glycine	77-80	insulin	Homo sapiens	0-7
11981030-7	2002	Finally, substitution of lysine residues 302 and 303 of ERalpha for glycine rendered a mutant ERalpha unable to interact with CaM whose transactivation activity became insensitive to W7.	Glycine	68-75	estrogen receptor 1	Homo sapiens	56-63
11981030-7	2002	Finally, substitution of lysine residues 302 and 303 of ERalpha for glycine rendered a mutant ERalpha unable to interact with CaM whose transactivation activity became insensitive to W7.	Glycine	68-75	estrogen receptor 1	Homo sapiens	94-101
12062406-6	2002	Further experiments showed that the peptide Arg-Gly-Asp-Ser blocked both fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to the erythrocyte membranes.	Glycine	48-51	fibrinogen beta chain	Homo sapiens	73-83
12062406-6	2002	Further experiments showed that the peptide Arg-Gly-Asp-Ser blocked both fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to the erythrocyte membranes.	Glycine	48-51	fibrinogen beta chain	Homo sapiens	151-161
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	58-61	tumor protein p53	Homo sapiens	71-74
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	135-138	tumor protein p53	Homo sapiens	54-57
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	135-138	tumor protein p53	Homo sapiens	71-74
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	135-138	tumor protein p53	Homo sapiens	71-74
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	135-138	tumor protein p53	Homo sapiens	71-74
12062426-1	2002	A common mutation in P53 protein occurs at amino acid residue 281 in the DNA binding domain (P53(gly(281))), which results in loss of transcriptional regulation of P53 target genes and has been reported to gain pro-oncogenic functions.	Glycine	97-100	tumor protein p53	Homo sapiens	21-24
12062426-1	2002	A common mutation in P53 protein occurs at amino acid residue 281 in the DNA binding domain (P53(gly(281))), which results in loss of transcriptional regulation of P53 target genes and has been reported to gain pro-oncogenic functions.	Glycine	97-100	tumor protein p53	Homo sapiens	93-96
12062426-1	2002	A common mutation in P53 protein occurs at amino acid residue 281 in the DNA binding domain (P53(gly(281))), which results in loss of transcriptional regulation of P53 target genes and has been reported to gain pro-oncogenic functions.	Glycine	97-100	tumor protein p53	Homo sapiens	93-96
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	58-61	tumor protein p53	Homo sapiens	54-57
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	58-61	tumor protein p53	Homo sapiens	71-74
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	58-61	tumor protein p53	Homo sapiens	71-74
11985794-0	2002	Tumor necrosis factor alpha-gene therapy for an established murine melanoma using RGD (Arg-Gly-Asp) fiber-mutant adenovirus vectors.	Glycine	91-94	tumor necrosis factor	Mus musculus	0-27
12420761-1	2002	Several new analogs of the known thrombin inhibitor NAPAP were synthesized, in which the P2 glycine residue was substituted by natural and unnatural amino acids.	Glycine	92-99	coagulation factor II	Rattus norvegicus	33-41
11970735-1	2002	Beta-endorphin and the synthetic beta-endorphin-like decapeptide Ser-Leu-Thr-Cys-Leu-Val-Lys-Gly-Phe-Tyr (referred to as immunorphin), corresponding to the sequence 364-373 of the CH3 domain of human immunoglobulin G heavy chain, were shown to stimulate concanavalin A-induced proliferation of T lymphocytes from the blood of healthy donors.	Glycine	93-96	proopiomelanocortin	Homo sapiens	33-47
11866478-2	2002	A synthetic peptide corresponding to the Gly(2460)-Pro(2495) domain of the RyR2, designated DPc10, enhanced the ryanodine binding activity and increased the sensitivity of the RyR2 to activating Ca(2+): the effects that resemble the typical phenotypes of cardiac diseases.	Glycine	41-44	ryanodine receptor 2	Homo sapiens	176-180
11900542-11	2002	The identified Gly-Cu linkage is unstable below pH approximately 6.5 and thus suggests a pH-dependent molecular mechanism by which PrP detects Cu2+ in the extracellular matrix or releases PrP-bound Cu2+ within the endosome.	Glycine	15-18	prion protein	Homo sapiens	131-134
11900542-11	2002	The identified Gly-Cu linkage is unstable below pH approximately 6.5 and thus suggests a pH-dependent molecular mechanism by which PrP detects Cu2+ in the extracellular matrix or releases PrP-bound Cu2+ within the endosome.	Glycine	15-18	prion protein	Homo sapiens	188-191
11866478-2	2002	A synthetic peptide corresponding to the Gly(2460)-Pro(2495) domain of the RyR2, designated DPc10, enhanced the ryanodine binding activity and increased the sensitivity of the RyR2 to activating Ca(2+): the effects that resemble the typical phenotypes of cardiac diseases.	Glycine	41-44	ryanodine receptor 2	Homo sapiens	75-79
11870087-5	2002	The amino acid sequence includes 6 Pro-Gly-Pro repeats, which are also present in the human orthologue protein (hSHIPPO 1) as well as in 2 other newly reported proteins of Drosophila melanogaster.	Glycine	39-42	outer dense fiber of sperm tails 3	Homo sapiens	112-121
11836426-2	2002	The DNA binding domain of EBNA1 is required for all three function, and a Gly-Arg-rich sequence between amino acids 325 and 376 is required for both the transcriptional activation and partitioning functions.	Glycine	74-77	EBNA-1	Human gammaherpesvirus 4	26-31
11861854-8	2002	During in vitro passage at 37 degrees C, the E176G mutation in rA2-P176 was rapidly changed from glycine to predominantly aspartic acid; mutations to cysteine or serine were also detected.	Glycine	97-104	UDP glucuronosyltransferase 1 family, polypeptide A7C	Rattus norvegicus	63-66
11724789-4	2002	Expressed as a glutathione S-transferase fusion protein, PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N(G)-monomethylarginine and asymmetric omega-N(G),N(G)-dimethylarginine derivatives on the recombinant glycine- and arginine-rich substrate in a processive manner with a specific activity of 144 pmol methyl groups transferred min(-1) mg(-1) enzyme.	Glycine	231-238	protein arginine methyltransferase 6	Homo sapiens	57-62
11805282-0	2002	Functional p53 chimeras containing the Epstein-Barr virus Gly-Ala repeat are protected from Mdm2- and HPV-E6-induced proteolysis.	Glycine	58-61	tumor protein p53	Homo sapiens	11-14
11882681-6	2002	In contrast, the intracellular application of the exogenous tyrosine kinase, cSrc, enhanced I(Gly) in CA1 neurons by 56 %.	Glycine	94-97	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	77-81
11882681-7	2002	cSrc also accelerated GlyR desensitization and increased the potency of glycine 2-fold (control EC(50) = 143 microM; cSrc EC(50) = 74 microM).	Glycine	72-79	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	0-4
11882681-7	2002	cSrc also accelerated GlyR desensitization and increased the potency of glycine 2-fold (control EC(50) = 143 microM; cSrc EC(50) = 74 microM).	Glycine	72-79	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	117-121
11714724-11	2002	In the fungal alpha1,2-mannosidase this arginine is replaced by glycine.	Glycine	64-71	mannosidase alpha class 1A member 2	Homo sapiens	14-34
11860374-0	2002	Glycine-extended gastrin-17 stimulates acid secretion only via CCK-2 receptor-induced histamine release in the totally isolated vascularly perfused rat stomach.	Glycine	0-7	cholecystokinin B receptor	Rattus norvegicus	63-77
11860374-12	2002	This study confirms that the stimulatory effect of Gly-G-17 on gastric acid secretion is via a CCK-2 receptor on the ECL cell.	Glycine	51-54	cholecystokinin B receptor	Rattus norvegicus	95-109
11834450-8	2002	We postulate that an arginine-glycine-aspartic acid sequence found on rat and mouse GHBP but absent in other species is responsible for the association of GHBP with the plasma membrane by binding to one or more integrins on the surface of liver cells.	Glycine	30-37	growth hormone receptor	Mus musculus	84-88
11834450-8	2002	We postulate that an arginine-glycine-aspartic acid sequence found on rat and mouse GHBP but absent in other species is responsible for the association of GHBP with the plasma membrane by binding to one or more integrins on the surface of liver cells.	Glycine	30-37	growth hormone receptor	Mus musculus	155-159
11841571-0	2002	Role of Ca2+ and calmodulin-dependent enzymes in the regulation of glycine transport in Muller glia.	Glycine	67-74	calmodulin 1	Homo sapiens	17-27
11841571-5	2002	In order to assess a function for Ca2+ and calmodulin (CaM)-dependent processes in the regulation of Gly transport, we explored the participation of Ca2+ concentration, CaM and Ca2+/CaM-dependent enzymes on Gly transporter activity.	Glycine	101-104	calmodulin 1	Homo sapiens	43-53
11841571-5	2002	In order to assess a function for Ca2+ and calmodulin (CaM)-dependent processes in the regulation of Gly transport, we explored the participation of Ca2+ concentration, CaM and Ca2+/CaM-dependent enzymes on Gly transporter activity.	Glycine	101-104	calmodulin 1	Homo sapiens	55-58
11841571-10	2002	We here demonstrate for the first time the participation of CaM, CaMKII and the actin cytoskeleton in the regulation of Gly transport in glia.	Glycine	120-123	calmodulin 1	Homo sapiens	60-63
11754492-0	2002	A positron-emitter labeled glycine(B) site antagonist, [(11)C]L-703,717, preferentially binds to a cerebellar NMDA receptor subtype consisting of GluR epsilon3 subunit in vivo, but not in vitro.	Glycine	27-34	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	Mus musculus	146-159
11883703-7	2002	CCK adenovirus-infected differentiated hNT cells also secrete glycine extended CCK products and the major molecular form produced co-eluted with CCK 8 Gly.	Glycine	62-69	cholecystokinin	Homo sapiens	0-3
11883703-7	2002	CCK adenovirus-infected differentiated hNT cells also secrete glycine extended CCK products and the major molecular form produced co-eluted with CCK 8 Gly.	Glycine	62-69	cholecystokinin	Homo sapiens	79-82
11883703-7	2002	CCK adenovirus-infected differentiated hNT cells also secrete glycine extended CCK products and the major molecular form produced co-eluted with CCK 8 Gly.	Glycine	62-69	cholecystokinin	Homo sapiens	79-82
11883703-7	2002	CCK adenovirus-infected differentiated hNT cells also secrete glycine extended CCK products and the major molecular form produced co-eluted with CCK 8 Gly.	Glycine	151-154	cholecystokinin	Homo sapiens	0-3
11883703-9	2002	These results also support the hypothesis that PC5 in differentiated neuronal cells is capable of processing pro CCK to glycine-extended CCK 8.	Glycine	120-127	cholecystokinin	Homo sapiens	113-116
11883703-9	2002	These results also support the hypothesis that PC5 in differentiated neuronal cells is capable of processing pro CCK to glycine-extended CCK 8.	Glycine	120-127	cholecystokinin	Homo sapiens	137-140
11814687-14	2002	A notable single nucleotide polymorphism in the coding region (cSNP) with an amino acid substitution of glycine (GGG) to arginine (AGG) was found at codon 335 of the REIC gene.	Glycine	104-111	dickkopf WNT signaling pathway inhibitor 3	Homo sapiens	166-170
11852237-3	2002	The CASH domain is characterized by internal repetitions of glycines and hydrophobic residues that correspond to the repetitive units of a predicted or observed right-handed beta-helix structure of the pectate lyase superfamily.	Glycine	60-68	CASP8 and FADD like apoptosis regulator	Homo sapiens	4-8
11862322-8	2002	On the other hand, insulin sensitivity was similar in the X/Ala (PPARgamma2) + Gly/Gly (IRS-1 972) and the Pro/Pro (PPARgamma2) + Gly/Gly (IRS-1).	Glycine	79-82	insulin	Homo sapiens	19-26
12224511-4	2002	EBNA1 contains an internal repeat exclusively composed of glycines and alanines that inhibits in cis the presentation of MHC class I-restricted T-cell epitopes and prevents ubiquitin/proteasome-dependent proteolysis in vitro and in vivo.	Glycine	58-66	EBNA-1	Human gammaherpesvirus 4	0-5
11862322-8	2002	On the other hand, insulin sensitivity was similar in the X/Ala (PPARgamma2) + Gly/Gly (IRS-1 972) and the Pro/Pro (PPARgamma2) + Gly/Gly (IRS-1).	Glycine	83-86	insulin	Homo sapiens	19-26
11862322-8	2002	On the other hand, insulin sensitivity was similar in the X/Ala (PPARgamma2) + Gly/Gly (IRS-1 972) and the Pro/Pro (PPARgamma2) + Gly/Gly (IRS-1).	Glycine	83-86	insulin	Homo sapiens	19-26
11862322-8	2002	On the other hand, insulin sensitivity was similar in the X/Ala (PPARgamma2) + Gly/Gly (IRS-1 972) and the Pro/Pro (PPARgamma2) + Gly/Gly (IRS-1).	Glycine	83-86	insulin	Homo sapiens	19-26
11735120-4	2001	We found that substitution of this glycine in H-2L(d) with a histidine substantially increased the proportion of peptide-free forms, although TAP binding was not abrogated.	Glycine	35-42	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	Mus musculus	142-145
11754839-3	2001	We have localized regions in the S1 binding domain of both subunits required for the transmission of allosteric signals from the glutamate binding NR2A subunit to the glycine binding NR1 subunit.	Glycine	167-174	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	147-151
11754839-3	2001	We have localized regions in the S1 binding domain of both subunits required for the transmission of allosteric signals from the glutamate binding NR2A subunit to the glycine binding NR1 subunit.	Glycine	167-174	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	183-186
11748846-6	2001	The glycine stretch may serve as a flexible linker between the functional domains of the TWIST protein, and as such may be subject to reduced evolutionary constraint.	Glycine	4-11	twist family bHLH transcription factor 1	Homo sapiens	89-94
11717497-3	2001	At the N-terminus of grancalcin there is a approximately 50 residue-long segment rich in glycines and prolines.	Glycine	89-97	grancalcin	Homo sapiens	21-31
11723250-7	2001	ALX 5407 completely inhibited glycine transport in the GlyT1 cells, with an IC(50) value of 3 nM, but had little or no activity at the human GlyT2 transporter, at other binding sites for glycine, or at other neurotransmitter transporters.	Glycine	30-37	solute carrier family 6 member 9	Homo sapiens	55-60
11718837-2	2001	Recently, gephyrin, a receptor-associated peripheral membrane protein, and collybistin, a gephyrin-binding protein have been shown to be pivotal for the formation of postsynaptic glycine and GABA(A) receptor clusters.	Glycine	179-186	gephyrin	Rattus norvegicus	10-18
11572853-9	2001	NR1(F639A) did not alter the agonist potency of glutamate but did produce a leftward shift in the glycine concentration response for receptors containing NR2A and NR2B subunits.	Glycine	98-105	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-3
11572853-9	2001	NR1(F639A) did not alter the agonist potency of glutamate but did produce a leftward shift in the glycine concentration response for receptors containing NR2A and NR2B subunits.	Glycine	98-105	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	154-158
11572853-10	2001	NR1(F639A) also reduced the potency of the competitive glycine antagonist 5,7-dichlorokynurenic acid and increased the efficacy of the glycine partial agonist 3-amino-1-hydroxy-2-pyrrolidinone ((+)-HA-966).	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-3
11572853-10	2001	NR1(F639A) also reduced the potency of the competitive glycine antagonist 5,7-dichlorokynurenic acid and increased the efficacy of the glycine partial agonist 3-amino-1-hydroxy-2-pyrrolidinone ((+)-HA-966).	Glycine	135-142	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	0-3
11572858-7	2001	A mutant SMN protein lacking both the tyrosine/glycine repeat (in exon 6) and exon 7 failed to sustain viability, indicating that the C terminus of the protein is critical for SMN activity.	Glycine	47-54	survival of motor neuron	Gallus gallus	9-12
11718837-2	2001	Recently, gephyrin, a receptor-associated peripheral membrane protein, and collybistin, a gephyrin-binding protein have been shown to be pivotal for the formation of postsynaptic glycine and GABA(A) receptor clusters.	Glycine	179-186	gephyrin	Rattus norvegicus	90-98
11825324-2	2001	Extension of the C-terminal of the B-chain with two arginine residues and the substitution of glycine for asparagine at position A-21 increases the isoelectric point, resulting in precipitation of the insulin at the injection site and a protracted absorption.	Glycine	94-101	insulin	Homo sapiens	201-208
11564737-3	2001	Earlier studies of the drug-sensitive NHE1 isoform have shown that residues within the fourth membrane-spanning helix (M4) (Phe(165), Phe(166), Leu(167), and Gly(178)) and a 66-amino acid segment encompassing M9 contribute significantly to drug recognition.	Glycine	158-161	solute carrier family 9 member A1	Homo sapiens	38-42
11551961-1	2001	The neurotransmitter glycine is removed from the synaptic cleft by two Na(+)-and Cl(-)-dependent transporters, the glial (GLYT1) and neuronal (GLYT2) glycine transporters.	Glycine	21-28	solute carrier family 6 member 9	Homo sapiens	122-127
11705702-4	2001	The increase in plasma TNFalpha and nitric oxide (NO) was also blunted by glycine feeding.	Glycine	74-81	tumor necrosis factor	Rattus norvegicus	23-31
11705702-6	2001	Glycine ameliorated oxidative stress and the impairment in antioxidant enzyme activities, inhibited NF-kappaB activation, and prevented expression of iNOS.	Glycine	0-7	nitric oxide synthase 2	Rattus norvegicus	150-154
11495912-0	2001	Involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinases in glycine-extended gastrin-induced dissociation and migration of gastric epithelial cells.	Glycine	86-93	gastrin	Mus musculus	103-110
11495912-2	2001	We report a novel stimulatory effect of glycine-extended gastrin(17) only on cell/cell dissociation and cell migration in a non-tumorigenic mouse gastric epithelial cell line (IMGE-5).	Glycine	40-47	gastrin	Mus musculus	57-64
11495912-3	2001	In contrast, both amidated and glycine-extended gastrin(17) stimulated proliferation of IMGE-5 cells via distinct receptors.	Glycine	31-38	gastrin	Mus musculus	48-55
11495912-4	2001	Glycine-extended gastrin(17)-induced dissociation preceded migration and was blocked by selective inhibitors of phosphatidylinositol 3-kinase (PI3-kinase) but did not require mitogen-activated protein (MAP) kinase activation.	Glycine	0-7	gastrin	Mus musculus	17-24
11495912-5	2001	Furthermore, glycine-extended gastrin(17) induced a PI3-kinase-mediated tyrosine phosphorylation of the adherens junction protein beta-catenin, partial dissociation of the complex between beta-catenin and the transmembrane protein E-cadherin, and delocalization of beta-catenin into the cytoplasm.	Glycine	13-20	gastrin	Mus musculus	30-37
11495912-5	2001	Furthermore, glycine-extended gastrin(17) induced a PI3-kinase-mediated tyrosine phosphorylation of the adherens junction protein beta-catenin, partial dissociation of the complex between beta-catenin and the transmembrane protein E-cadherin, and delocalization of beta-catenin into the cytoplasm.	Glycine	13-20	cadherin 1	Mus musculus	231-241
11495912-6	2001	Long lasting activation of MAP kinases by glycine-extended gastrin(17) was specifically required for the migratory response, in contrast to the involvement of a rapid and transient MAP kinase activation in the proliferative response to both amidated and glycine-extended gastrin(17).	Glycine	42-49	gastrin	Mus musculus	59-66
11711044-3	2001	The cholinesterase inhibitor physostigmine at a dose of 3.2 microg/side and D-cycloserine (1.0 and 10 microg/side), which is a partial agonist acting at the glycine binding site of the NMDA receptor/channel complex, reduced the increase in working memory errors induced by 100 ng/side interleukin-1beta.	Glycine	157-164	interleukin 1 beta	Rattus norvegicus	285-302
11691584-3	2001	We have identified a novel missense mutation which substitutes a glycine for an aspartic acid residue in the thrombospondin (TSP) type 3 calcium-binding domain of COMP in a patient diagnosed with PSACH.	Glycine	65-72	thrombospondin 1	Homo sapiens	125-128
11691584-3	2001	We have identified a novel missense mutation which substitutes a glycine for an aspartic acid residue in the thrombospondin (TSP) type 3 calcium-binding domain of COMP in a patient diagnosed with PSACH.	Glycine	65-72	thrombospondin 1	Homo sapiens	109-123
11600567-5	2001	A greater reduction was seen when both L80 and L81 were substituted with glycine, and complete loss of affinity for IGF-I and IGF-II occurred when all three targeted amino acids were changed to glycine.	Glycine	194-201	insulin like growth factor 1	Homo sapiens	116-121
11594778-1	2001	N-Myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the cotranslational and/or posttranslational transfer of myristate to the amino terminal glycine residue of a number of important proteins especially the non-receptor tyrosine kinases whose activity is important for tumorigenesis.	Glycine	167-174	N-myristoyltransferase 1	Homo sapiens	0-22
11594778-1	2001	N-Myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the cotranslational and/or posttranslational transfer of myristate to the amino terminal glycine residue of a number of important proteins especially the non-receptor tyrosine kinases whose activity is important for tumorigenesis.	Glycine	167-174	N-myristoyltransferase 1	Homo sapiens	24-27
11568287-2	2001	Patients with CETP deficiency caused by mutation of the CETP gene [D442G; a missense mutation (Asp442--&gt;Gly)] have been reported to show high plasma HDL levels.	Glycine	107-110	cholesteryl ester transfer protein	Homo sapiens	14-18
11549721-6	2001	On purified neurohypophysial nerve endings, activation of strychnine-sensitive GlyRs by taurine or glycine primarily inhibits the high K(+)-induced rise in [Ca(2+)](i) and subsequent release of vasopressin.	Glycine	99-106	arginine vasopressin	Homo sapiens	194-205
11563854-5	2001	Stimulation of HAECs with gly-ox-HDL elicited a marked increase in caspase 3 activity and the expressions of active caspase 3 and caspase 9, whereas concomitant treatment with a caspase 3 inhibitor significantly blocked gly-ox-HDL-induced apoptosis of HAECs.	Glycine	26-29	caspase 3	Homo sapiens	67-76
11563854-5	2001	Stimulation of HAECs with gly-ox-HDL elicited a marked increase in caspase 3 activity and the expressions of active caspase 3 and caspase 9, whereas concomitant treatment with a caspase 3 inhibitor significantly blocked gly-ox-HDL-induced apoptosis of HAECs.	Glycine	26-29	caspase 3	Homo sapiens	116-125
11563854-5	2001	Stimulation of HAECs with gly-ox-HDL elicited a marked increase in caspase 3 activity and the expressions of active caspase 3 and caspase 9, whereas concomitant treatment with a caspase 3 inhibitor significantly blocked gly-ox-HDL-induced apoptosis of HAECs.	Glycine	26-29	caspase 3	Homo sapiens	116-125
11563854-6	2001	The release of cytochrome c into cytosols markedly increased in HAECs during the treatment with gly-ox-HDL.	Glycine	96-99	cytochrome c, somatic	Homo sapiens	15-27
11563854-7	2001	The increased expressions of Bax and Bad were detected in HAECs incubated for 24 h with gly-ox-HDL, but gly-ox-HDL failed to interfere with the expression of Bcl-2 and Bcl-x.	Glycine	88-91	BCL2 associated X, apoptosis regulator	Homo sapiens	29-32
11402024-2	2001	The obtained sequence indicates that the amino terminus of this fragment corresponds to Gly-1126 of ErbB-2.	Glycine	88-91	erb-b2 receptor tyrosine kinase 2	Homo sapiens	100-106
11500310-6	2001	In addition, internalization of the wild-type receptor and the DSEL mutant is stimulated by the PTH analog [Gly(1),Arg(19)]hPTH-(1-28), which does not stimulate phospholipase C. Forskolin, IBMX, and the active phorbol ester, phorbol-12-myristate-13-acetate, did not promote receptor internalization or increase PTH-induced internalization.	Glycine	108-111	dermatan sulfate epimerase like	Homo sapiens	63-67
11435434-1	2001	Epstein-Barr virus (EBV)-encoded nuclear antigen 1 (EBNA1) includes a unique glycine-alanine repeat domain that inhibits the endogenous presentation of cytotoxic T lymphocyte (CTL) epitopes through the class I pathway by blocking proteasome-dependent degradation of this antigen.	Glycine	77-84	EBNA-1	Human gammaherpesvirus 4	52-57
11435434-6	2001	These observations provide, for the first time, evidence that the glycine-alanine repeat-mediated proteasomal block on EBNA1 can be reversed by specifically targeting this antigen for rapid degradation resulting in enhanced CD8+ T cell-mediated recognition in vitro and in vivo.	Glycine	66-73	EBNA-1	Human gammaherpesvirus 4	119-124
11500310-6	2001	In addition, internalization of the wild-type receptor and the DSEL mutant is stimulated by the PTH analog [Gly(1),Arg(19)]hPTH-(1-28), which does not stimulate phospholipase C. Forskolin, IBMX, and the active phorbol ester, phorbol-12-myristate-13-acetate, did not promote receptor internalization or increase PTH-induced internalization.	Glycine	108-111	parathyroid hormone	Homo sapiens	96-99
11500310-6	2001	In addition, internalization of the wild-type receptor and the DSEL mutant is stimulated by the PTH analog [Gly(1),Arg(19)]hPTH-(1-28), which does not stimulate phospholipase C. Forskolin, IBMX, and the active phorbol ester, phorbol-12-myristate-13-acetate, did not promote receptor internalization or increase PTH-induced internalization.	Glycine	108-111	parathyroid hormone	Homo sapiens	124-127
11513726-7	2001	However, a glycine residue adjacent to the D-5 inositol-phosphate-binding site in DAPP1 is substituted for a larger alanine residue in TAPP1, which also induces a conformational change in the neighbouring residues.	Glycine	11-18	dual adaptor of phosphotyrosine and 3-phosphoinositides 1	Homo sapiens	82-87
11513726-8	2001	We show that mutation of this glycine to alanine in DAPP1 converts DAPP1 into a TAPP1-like PH domain that only interacts with PtdIns(3,4)P(2), whereas the alanine to glycine mutation in TAPP1 permits the TAPP1 PH domain to interact with PtdIns(3,4,5)P(3).	Glycine	30-37	dual adaptor of phosphotyrosine and 3-phosphoinositides 1	Homo sapiens	52-57
11513726-8	2001	We show that mutation of this glycine to alanine in DAPP1 converts DAPP1 into a TAPP1-like PH domain that only interacts with PtdIns(3,4)P(2), whereas the alanine to glycine mutation in TAPP1 permits the TAPP1 PH domain to interact with PtdIns(3,4,5)P(3).	Glycine	166-173	dual adaptor of phosphotyrosine and 3-phosphoinositides 1	Homo sapiens	52-57
11513726-8	2001	We show that mutation of this glycine to alanine in DAPP1 converts DAPP1 into a TAPP1-like PH domain that only interacts with PtdIns(3,4)P(2), whereas the alanine to glycine mutation in TAPP1 permits the TAPP1 PH domain to interact with PtdIns(3,4,5)P(3).	Glycine	30-37	dual adaptor of phosphotyrosine and 3-phosphoinositides 1	Homo sapiens	67-72
11601677-3	2001	Following activation of procarboxypeptidase U by thrombin-thrombomodulin, the resulting enzyme activity cleaves p-OH-Hip-Arg and the generated p-OH-hippuric acid is converted by hippuricase to p-hydroxybenzoic acid and glycine.	Glycine	219-226	coagulation factor II, thrombin	Homo sapiens	49-57
11589724-15	2001	Pharmacological characterisation of the 287V --&gt; F CCK-B/gastrin receptor reveals wild-type affinities for G17 amide, glycine-extended gastrin, CCK-8S and L-365,260.	Glycine	121-128	cholecystokinin B receptor	Homo sapiens	54-59
11589724-15	2001	Pharmacological characterisation of the 287V --&gt; F CCK-B/gastrin receptor reveals wild-type affinities for G17 amide, glycine-extended gastrin, CCK-8S and L-365,260.	Glycine	121-128	cholecystokinin B receptor	Homo sapiens	60-76
11527579-2	2001	Allosteric activators such as D-glucose-6-phosphate and glycine increase the affinity of PEPC for its substrate PEP at pH 8.0 and pH 7.0.	Glycine	56-63	phosphoenolpyruvate carboxylase 2	Zea mays	89-92
11500467-12	2001	In isolated splenic macrophages, glycine blunted translocation of the p65 subunit of NF-kappaB into the nucleus, superoxide generation, and TNF-alpha production caused by PG-PS.	Glycine	33-40	tumor necrosis factor	Rattus norvegicus	140-149
11527946-10	2001	Glycine substitution for selective leucine residues confirmed that MYOC-MYOC interactions occurred mainly within the leucine zipper domain.	Glycine	0-7	myocilin	Homo sapiens	67-71
11527946-10	2001	Glycine substitution for selective leucine residues confirmed that MYOC-MYOC interactions occurred mainly within the leucine zipper domain.	Glycine	0-7	myocilin	Homo sapiens	72-76
11486036-5	2001	YY1 was acetylated in two regions: both p300 and PCAF acetylated the central glycine-lysine-rich domain of residues 170 to 200, and PCAF also acetylated YY1 at the C-terminal DNA-binding zinc finger domain.	Glycine	77-84	YY1 transcription factor	Homo sapiens	0-3
11566325-7	2001	The replacement of glycine by the arginine residue in the fifth position of the beta-amyloid peptide sequence changes the coordination modes of a peptide to metal ion in the physiological pH range.	Glycine	19-26	amyloid beta precursor protein	Homo sapiens	80-100
11520168-4	2001	RESULTS: (1) IL-1- and TNF-stimulated release of aggrecan was associated with cleavage of aggrecan within the C-terminus at the ADAM-TS4 and ADAM-TS5-sensitive sites, Glu(1480)-Gly(1481), Glu(1667)-Gly(1668), and Glu(1871)-Leu(1872).	Glycine	177-180	tumor necrosis factor	Homo sapiens	23-26
12540263-5	2001	Expression of GLYT1 within the brain correlates with NMDA receptor expression patterns and it has been suggested that GLYT1 may regulate synaptic glycine concentrations.	Glycine	146-153	solute carrier family 6 member 9	Homo sapiens	118-123
12540263-6	2001	With the development of selective and potent non-transported inhibitors of GLYT1 it should be possible to elevate synaptic glycine concentrations more effectively and thereby to increase NMDA receptor activity.	Glycine	123-130	solute carrier family 6 member 9	Homo sapiens	75-80
11502818-7	2001	The P450scc mutation, an in-frame insertion of Gly and Asp between Asp271 and Val272, was inserted into a catalytically active fusion protein of the P450scc system (H2N-P450scc-Adrenodoxin Reductase-Adrenodoxin-COOH), completely inactivating enzymatic activity.	Glycine	47-50	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	4-11
11502818-7	2001	The P450scc mutation, an in-frame insertion of Gly and Asp between Asp271 and Val272, was inserted into a catalytically active fusion protein of the P450scc system (H2N-P450scc-Adrenodoxin Reductase-Adrenodoxin-COOH), completely inactivating enzymatic activity.	Glycine	47-50	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	149-156
11502818-7	2001	The P450scc mutation, an in-frame insertion of Gly and Asp between Asp271 and Val272, was inserted into a catalytically active fusion protein of the P450scc system (H2N-P450scc-Adrenodoxin Reductase-Adrenodoxin-COOH), completely inactivating enzymatic activity.	Glycine	47-50	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	149-156
11733654-4	2001	DNA sequence analysis of the propositus demonstrated a point mutation at codon 365 (GGA-CGA), resulting in a Gly-Arg substitution.	Glycine	109-112	chromogranin A	Homo sapiens	88-91
11457520-0	2001	Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22.	Glycine	77-84	cholecystokinin	Homo sapiens	68-71
11457520-0	2001	Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22.	Glycine	77-84	cholecystokinin	Homo sapiens	94-97
11520168-4	2001	RESULTS: (1) IL-1- and TNF-stimulated release of aggrecan was associated with cleavage of aggrecan within the C-terminus at the ADAM-TS4 and ADAM-TS5-sensitive sites, Glu(1480)-Gly(1481), Glu(1667)-Gly(1668), and Glu(1871)-Leu(1872).	Glycine	198-201	tumor necrosis factor	Homo sapiens	23-26
11457520-8	2001	Production of glycine-extended CCK processing products was evaluated by treatment of media with carboxypeptidase B followed by analysis with a CCK Gly RIA.	Glycine	14-21	cholecystokinin	Homo sapiens	31-34
11457520-8	2001	Production of glycine-extended CCK processing products was evaluated by treatment of media with carboxypeptidase B followed by analysis with a CCK Gly RIA.	Glycine	14-21	cholecystokinin	Homo sapiens	143-146
11459451-4	2001	The affinities of these conjugates were estimated by their inhibition of the accumulation rate of Gly-Sar, a well-established substrate for PEPT1.	Glycine	98-101	solute carrier family 15 member 1	Homo sapiens	140-145
11683510-10	2001	In this communication, the gas-phase ion chemistry responsible for the facile cleavage between Gln and Gly residues is investigated, particularly in relation to Proline Rich Protein-1.	Glycine	103-106	opiorphin prepropeptide	Homo sapiens	161-183
11415439-2	2001	They contain two and three thioredoxin boxes (Cys-Gly-His-Cys) respectively and, like PDI, may be involved in the folding of nascent proteins.	Glycine	50-53	thioredoxin 1	Rattus norvegicus	27-38
11457520-8	2001	Production of glycine-extended CCK processing products was evaluated by treatment of media with carboxypeptidase B followed by analysis with a CCK Gly RIA.	Glycine	147-150	cholecystokinin	Homo sapiens	31-34
11457520-10	2001	The predominant forms co-eluted with CCK 12 Gly and CCK 22 Gly on gel filtration chromatography.	Glycine	59-62	cholecystokinin	Homo sapiens	52-55
11508863-3	2001	The early systemic increase of the proinflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL) -6 as well as the secretion of the antiinflammatory cytokine IL-10 was reduced by glycine.	Glycine	204-211	tumor necrosis factor	Rattus norvegicus	61-88
11508863-3	2001	The early systemic increase of the proinflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL) -6 as well as the secretion of the antiinflammatory cytokine IL-10 was reduced by glycine.	Glycine	204-211	interleukin 6	Rattus norvegicus	105-124
11508863-4	2001	Tissue cytokine mRNA expression (TNF-alpha, IL-1beta, IL-10) was decreased in the lung and the liver but not in the mesenteric lymph node or ileum, in the glycine-fed group.	Glycine	155-162	tumor necrosis factor	Rattus norvegicus	33-42
11508863-4	2001	Tissue cytokine mRNA expression (TNF-alpha, IL-1beta, IL-10) was decreased in the lung and the liver but not in the mesenteric lymph node or ileum, in the glycine-fed group.	Glycine	155-162	interleukin 1 beta	Rattus norvegicus	44-52
11444854-4	2001	JDD1 has a J domain that is unique to the DnaJ family but lacks the G/F region (a region that is rich in the amino acids glycine and phenylalanine) and the zinc finger region (also known as the cysteine-rich region)-both characteristic to the DnaJ.	Glycine	121-128	DnaJ heat shock protein family (Hsp40) member C9	Rattus norvegicus	0-4
11328808-3	2001	In this mutant, two hydrophobic residues at the tip of a proposed hydrophobic plug between actin subdomains 3 and 4, Val(266) and Leu(267), were mutated to Gly.	Glycine	156-159	actin	Saccharomyces cerevisiae S288C	91-96
11408273-5	2001	Treatment with GdCl(3) or glycine prevented CCl(4)-induced increases in transforming growth factor (TGF)-beta 1 protein levels and expression.	Glycine	26-33	transforming growth factor, beta 1	Rattus norvegicus	72-111
11418466-2	2001	The molecular basis for the observed phenotype is a substitution of glycine for aspartate in the strictly conserved codon 218 (D218G) of the amino-terminal zinc finger loop of the transcription factor GATA1.	Glycine	68-75	GATA binding protein 1	Homo sapiens	201-206
11456285-6	2001	Changes from baseline of early (p &lt; 0.05), late (p &lt; 0.05), and total insulin (p &lt; 0.02) responses were higher in the glycine group than in controls.	Glycine	127-134	insulin	Homo sapiens	76-83
11418470-11	2001	RGDS (Arg-Gly-Asp-Ser) or antibodies to alpha5beta1 or alphaIIbbeta3 integrins caused a partial decrease in LPA-induced deposition of FITC-FN.	Glycine	10-13	fibronectin 1	Homo sapiens	134-141
11433018-9	2001	In addition, we show that converting a highly conserved glycine residue (G(59)) within Nhp2p central domain to glutamate significantly reduces cell growth at 30 and 37 degrees C. Remarkably, this modification affects the steady-state levels of H/ACA snoRNAs and the strength of Nhp2p association with these RNAs to varying degrees, depending on the nature of the H/ACA snoRNA.	Glycine	56-63	snoRNA-binding protein NHP2	Saccharomyces cerevisiae S288C	87-92
11433018-9	2001	In addition, we show that converting a highly conserved glycine residue (G(59)) within Nhp2p central domain to glutamate significantly reduces cell growth at 30 and 37 degrees C. Remarkably, this modification affects the steady-state levels of H/ACA snoRNAs and the strength of Nhp2p association with these RNAs to varying degrees, depending on the nature of the H/ACA snoRNA.	Glycine	56-63	snoRNA-binding protein NHP2	Saccharomyces cerevisiae S288C	278-283
11418128-3	2001	Inhibition of TNFalpha-induced degradation was achieved by insertion of octamers containing three alanines or valines, interspersed by no more then three consecutive glycines.	Glycine	166-174	tumor necrosis factor	Homo sapiens	14-22
11395604-13	2001	Glycine administration in septic animals decreased alpha-gluthathione S-transferase and tumor necrosis factor-alpha by 43% and 80% (p &lt;.05).	Glycine	0-7	tumor necrosis factor	Rattus norvegicus	88-115
11395604-15	2001	CONCLUSIONS: It appears that the beneficial effect of glycine on hepatocyte function and integrity in sepsis may be mediated via down-regulation of tumor necrosis factor-alpha.	Glycine	54-61	tumor necrosis factor	Rattus norvegicus	148-175
11358908-10	2001	All tumour regions showed a point mutation in p53 gene at exon 7 (GGC (glycine)--&gt;GTC (valine) at codon 245).	Glycine	71-78	tumor protein p53	Homo sapiens	46-49
11378370-2	2001	Fibronectin contains the active sequence Arg-Gly-Asp (RGD), along with its synergic site Pro-His-Ser-Arg-Asn (PHSRN).	Glycine	45-48	fibronectin 1	Homo sapiens	0-11
11350743-4	2001	Twisting integrin receptors with RGD (Arg-Gly-Asp)-containing peptide-coated beads increased endothelin-1 (ET-1) gene expression by &gt;100%.	Glycine	42-45	endothelin 1	Homo sapiens	93-105
11350743-4	2001	Twisting integrin receptors with RGD (Arg-Gly-Asp)-containing peptide-coated beads increased endothelin-1 (ET-1) gene expression by &gt;100%.	Glycine	42-45	endothelin 1	Homo sapiens	107-111
11471731-5	2001	In 20 mm phosphate and citrate at pH 7.0, the results are similar, i.e., EPO suffered a substantial aggregation, while it showed little aggregation in 20 mm Tris or histidine at pH 7.0 and 20 mm glycine at pH 6.3 under identical heat treatment.	Glycine	195-202	erythropoietin	Homo sapiens	73-76
11456285-8	2001	In conclusion, a morning dose of glycine 5 g orally increased early, late and total insulin responses without changes in insulin action in healthy first-degree relatives of Type 2 diabetes mellitus patients.	Glycine	33-40	insulin	Homo sapiens	84-91
11352579-5	2001	The specificity of MR1 lies in the ability of this glycine residue to assume the restricted conformation needed to form a type II" beta-hairpin turn more easily, and demonstrates that a peptide antigen can be used to generate a conformational epitope.	Glycine	51-58	major histocompatibility complex, class I-related	Homo sapiens	19-22
11278474-7	2001	Protection assays indicate that EL1 cysteines are less accessible in the presence of all co-transported substrates: Na(+), Cl(-), and glycine.	Glycine	134-141	ELAV (embryonic lethal, abnormal vision)-like 2 (Hu antigen B)	Xenopus laevis	32-35
11343252-4	2001	MBsep transports both glycine and taurine conjugated bile salts.	Glycine	22-29	ATP-binding cassette, sub-family B (MDR/TAP), member 11	Mus musculus	0-5
11336637-0	2001	Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis.	Glycine	8-15	ATP binding cassette subfamily B member 1	Homo sapiens	76-80
11336637-0	2001	Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis.	Glycine	24-31	ATP binding cassette subfamily B member 1	Homo sapiens	76-80
11336637-2	2001	Human MDR1 variants with mutations affecting a conserved glycine residue within the ABC signature of either or both ABC units (G534D, G534V, G1179D and G534D/G1179D) were expressed and characterized in Spodoptera frugiperda (Sf9) cell membranes.	Glycine	57-64	ATP binding cassette subfamily B member 1	Homo sapiens	6-10
11317364-6	2001	Most mutations resulted in substitutions for glycine: one of these, a doublet GG>CC transversion, created a unique Gly-->Pro missense mutation in the triple helical domain of COL1A2.	Glycine	45-52	collagen type I alpha 2 chain	Homo sapiens	175-181
11317364-6	2001	Most mutations resulted in substitutions for glycine: one of these, a doublet GG>CC transversion, created a unique Gly-->Pro missense mutation in the triple helical domain of COL1A2.	Glycine	115-118	collagen type I alpha 2 chain	Homo sapiens	175-181
11317364-7	2001	Two rare triple helical Gly-->Glu substitutions in COL1A2 are also described.	Glycine	24-27	collagen type I alpha 2 chain	Homo sapiens	51-57
11312282-0	2001	Substance P abolishes the facilitatory effect of ATP on spontaneous glycine release in neurons of the trigeminal nucleus pars caudalis.	Glycine	68-75	tachykinin precursor 1	Homo sapiens	0-11
11319765-3	2001	Two glycine transporters have been cloned: GLYT1, mainly expressed by glial cells and shown to colocalize with NMDA receptors, and GLYT2, exclusively expressed by neurons and colocalized with the inhibitory glycine receptors.	Glycine	4-11	solute carrier family 6 member 9	Homo sapiens	43-48
11312282-13	2001	Because SP inhibits the ATP stimulation of glycine release, SP may play a significant role in hyperalgesia or chronic pain.	Glycine	43-50	tachykinin precursor 1	Homo sapiens	8-10
11312282-13	2001	Because SP inhibits the ATP stimulation of glycine release, SP may play a significant role in hyperalgesia or chronic pain.	Glycine	43-50	tachykinin precursor 1	Homo sapiens	60-62
11278633-8	2001	These results demonstrate that the alpha(M)(Lys(245)-Arg(261)) segment, a site of the major sequence and structure difference among alpha(M)I-, alpha(X)I-, and alpha(L)I-domains, is responsible for recognition of a small segment of fibrinogen, gammaThr(383)-Gly(395), by serving as ligand binding site.	Glycine	258-261	fibrinogen beta chain	Homo sapiens	232-242
11319720-2	2001	A slight modification of these formulas allows the calculation of insulin resistance indices (IRI), ie, IRI(gly) and IRI(ffa).	Glycine	108-111	insulin	Homo sapiens	66-73
11287119-4	2001	In this report, we show that the C-terminal deletion and two point mutations (Asp--&gt;Gly at residue 91 and Asp--&gt;Asn at residue 437) in v-Rel make it resistant to cleavage by the cell-death protease caspase-3.	Glycine	87-90	caspase 3	Gallus gallus	204-213
11302743-3	2001	Here, we constructed a mutant by substituting the N-terminal glycine of Pr55(gag) with alanine to demonstrate that N-myristoylation of Pr55(gag) is required for efficient env protein transportation to the cell surface.	Glycine	61-68	endogenous retrovirus group W member 1, envelope	Homo sapiens	171-174
11301188-7	2001	Determination of cytokine mRNA in the course of Fas-mediated apoptosis in the presence of Tf or Tf-Gly showed upregulation of mRNA for Fas ligand and TNF-alpha in CD56(+) and downregulation of these transcripts along with upregulation of mRNA for interleukin-10 in CD3(+) marrow cells.	Glycine	99-102	tumor necrosis factor	Mus musculus	150-159
11254474-6	2001	min(-1) (GLY), P &lt; 0.05] and during exercise at both intensities [45%: 0.63 +/- 0.14 (CON) vs. 0.04 +/- 0.12 (GLY); 65%: 0.73 +/- 0.14 (CON) vs. 0.04 +/- 0.17 mg. kg(-1).	Glycine	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
11254474-7	2001	min(-1) (GLY), P &lt; 0.05].	Glycine	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
11301188-7	2001	Determination of cytokine mRNA in the course of Fas-mediated apoptosis in the presence of Tf or Tf-Gly showed upregulation of mRNA for Fas ligand and TNF-alpha in CD56(+) and downregulation of these transcripts along with upregulation of mRNA for interleukin-10 in CD3(+) marrow cells.	Glycine	99-102	interleukin 10	Mus musculus	247-261
11274274-2	2001	Immunoreactive AM in human plasma consists of the biologically active mature form, AM (1-52)-CONH2 (mAM) and the intermediate form, AM-gly-COOH (iAM).	Glycine	135-138	activating transcription factor 7 interacting protein	Mus musculus	15-17
11304516-4	2001	The pretreatment of vascular smooth muscle cells with Ang-(1-7) followed by treatment with acidic glycine to remove surface-bound peptide resulted in a significant decrease in [(125)I]Ang II binding; however, reduced Ang II binding was observed only at micromolar concentrations of Ang-(1-7).	Glycine	98-105	angiotensinogen	Rattus norvegicus	184-190
11304516-4	2001	The pretreatment of vascular smooth muscle cells with Ang-(1-7) followed by treatment with acidic glycine to remove surface-bound peptide resulted in a significant decrease in [(125)I]Ang II binding; however, reduced Ang II binding was observed only at micromolar concentrations of Ang-(1-7).	Glycine	98-105	angiotensinogen	Rattus norvegicus	217-223
11401448-4	2001	CNRc1 and c2 lack the Arg-Gly-Asp (RGD) sequence that is conserved in the EC1 of CNR1-8, which is necessary for binding to Reelin.	Glycine	26-29	cannabinoid receptor 1	Homo sapiens	81-87
11289145-4	2001	Gephyrin is a rat glycine receptor-associated protein, which forms submembranous complexes and anchor glycine or gamma-aminobutyric acidA receptors to microtubules.	Glycine	18-25	gephyrin	Rattus norvegicus	0-8
11359614-5	2001	DNA sequence analysis of the pbs1-2 allele showed it to be a missense mutation that caused a glycine to arginine substitution in the activation segment of PBS1, a region known to regulate substrate binding and catalytic activity in many protein kinases.	Glycine	93-100	Protein kinase superfamily protein	Arabidopsis thaliana	29-33
11359614-5	2001	DNA sequence analysis of the pbs1-2 allele showed it to be a missense mutation that caused a glycine to arginine substitution in the activation segment of PBS1, a region known to regulate substrate binding and catalytic activity in many protein kinases.	Glycine	93-100	Protein kinase superfamily protein	Arabidopsis thaliana	155-159
11124960-7	2001	Moreover, residues (Glu(36), Trp(67), Asp(68), Trp(73), and Gly(109)) which were shown to be crucial for VIP binding are gathered around a groove that is essentially negatively charged.	Glycine	60-63	vasoactive intestinal peptide	Homo sapiens	105-108
11237737-4	2001	Single point mutation of four cysteine residues in extracellular loops to glycine (C35G, C267G, C273G, and C275G) resulted in a complete loss of binding for [125I]-NDP-MSH.	Glycine	74-81	proopiomelanocortin	Homo sapiens	168-171
11295495-5	2001	We have shown that a Gly-rich region (GRR) at the C-terminal domain of p50 is one important processing signal and that it interferes with processing of the ubiquitinated precursor by the 26S proteasome.	Glycine	21-24	nuclear factor kappa B subunit 1	Homo sapiens	71-74
11243884-6	2001	In addition, SN2 also transports serine, alanine, and glycine.	Glycine	54-61	solute carrier family 38 member 5	Homo sapiens	13-16
11161043-8	2001	Another Gly betaine accumulator, sugar beet (Beta vulgaris), also showed salt-responsive increases in SAHH and ADK activities and protein whereas tobacco (Nicotiana tabacum) and canola (Brassica napus), which do not accumulate Gly betaine, did not show comparable changes in these enzymes.	Glycine	8-11	adenosine kinase	Arabidopsis thaliana	111-114
11171042-3	2001	The Y84G (Tyr(84)--&gt;Gly) allele of PDEgamma has previously been shown in experiments carried out in vitro to reduce the regulatory control of the PDE catalytic core (PDEalphabeta) exerted by the wild-type gamma subunit.	Glycine	23-26	phosphodiesterase 6H, cGMP-specific, cone, gamma	Mus musculus	38-46
11159884-0	2001	Glycine supply to human enterocytes mediated by high-affinity basolateral GLYT1.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	74-79
11159884-8	2001	Protein kinase C activation reduced maximum velocity for GLYT1-mediated glycine uptake without effect on the Michaelis constant.	Glycine	72-79	solute carrier family 6 member 9	Homo sapiens	57-62
11159884-10	2001	CONCLUSIONS: Enterocytes express GLYT1 along the length of the crypt-villus axis, where it mediates high-affinity basolateral glycine uptake.	Glycine	126-133	solute carrier family 6 member 9	Homo sapiens	33-38
11239221-2	2001	STUDY DESIGN AND METHODS: With a target of collecting from the peripheral blood &gt; or = 4 x 10(6) CD34+ cells per kg of body weight of the recipient, the short-course administration of glycosylated G-CSF (gly-G-CSF) in 30 healthy donors for an allogeneic transplantation was investigated.	Glycine	187-190	CD34 molecule	Homo sapiens	100-104
11257802-0	2001	Inhibition of platelet aggregation of a mutant proinsulin molecule engineered by introduction of a native Arg-Gly-Asp sequence.	Glycine	110-113	insulin	Homo sapiens	47-57
11741253-3	2001	The hPepT1-GFP fusion construct was then transfected into Caco-2 and HeLa cells, and drug inhibition was studied by inhibiting 3H-Gly-Sar uptake.	Glycine	130-133	solute carrier family 15 member 1	Homo sapiens	4-10
11460528-2	2001	Reverse phase chromatography, isoelectric focussing, electrospray mass spectrometry, and tryptic peptide mass mapping have shown that chains with heterozygous mutations of gamma 284 Gly--&gt;Arg, B beta 316 Asp--&gt;Tyr and gamma 371 Thr--&gt;Ile are absent from plasma fibrinogen.	Glycine	182-185	fibrinogen beta chain	Homo sapiens	270-280
11096062-6	2001	One of the APG gene products, Apg12p, is covalently attached to Apg5p via the C-terminal Gly of Apg12p as in the case of ubiquitylation, and this conjugation is essential for autophagy.	Glycine	89-92	autophagy related 12	Homo sapiens	30-36
11096062-6	2001	One of the APG gene products, Apg12p, is covalently attached to Apg5p via the C-terminal Gly of Apg12p as in the case of ubiquitylation, and this conjugation is essential for autophagy.	Glycine	89-92	autophagy related 5	Homo sapiens	64-69
11096062-6	2001	One of the APG gene products, Apg12p, is covalently attached to Apg5p via the C-terminal Gly of Apg12p as in the case of ubiquitylation, and this conjugation is essential for autophagy.	Glycine	89-92	autophagy related 12	Homo sapiens	96-102
11163793-6	2001	Replacement of a histidine at position 463 in hKv1.5 by glycine confirmed this hypothesis making this H463G mutant channel sensitive to removal of [K(+)](o) even at pH(o) 7.4.	Glycine	56-63	potassium voltage-gated channel subfamily A member 5	Homo sapiens	46-52
11257802-2	2001	The constructed Arg-Gly-Asp (RGD)-proinsulin gene was cloned into a temperature-inducible vector pBV220 and expressed in Escherichia coli.	Glycine	20-23	insulin	Homo sapiens	34-44
11396606-6	2001	It is believed that the termination of the different synaptic actions of glycine is produced by rapid re-uptake through two sodium-and-chloride-coupled transporters, GLYT1 and GLYT2, located in the plasma membrane of glial cells or pre-synaptic terminals, respectively.	Glycine	73-80	solute carrier family 6 member 9	Homo sapiens	166-171
11697044-1	2001	Several new analogs of the known thrombin inhibitor NAPAP were synthesized, in which the P2 glycine residue was substituted by natural and unnatural amino acids.	Glycine	92-99	coagulation factor II	Rattus norvegicus	33-41
11319794-4	2001	The collision-induced dissociation spectra obtained from the PRP-1 tryptic peptides and the synthetic peptides indicate that facile Gln-Gly cleavage occurs when an X-Gln-Gly-Y sequence is present in a peptide, where X is any amino acid and Y any amino acid other than Gly.	Glycine	136-139	opiorphin prepropeptide	Homo sapiens	61-66
11287679-1	2001	The structure and biological activities of two disulphide isomers of a C-region deletion mutant of insulin-like growth factor-I (IGF-I) which has an Asn--Gly link engineered at the junction of the A- and B-regions were studied before and after chemical cleavage.	Glycine	154-157	insulin like growth factor 1	Homo sapiens	99-127
11287679-1	2001	The structure and biological activities of two disulphide isomers of a C-region deletion mutant of insulin-like growth factor-I (IGF-I) which has an Asn--Gly link engineered at the junction of the A- and B-regions were studied before and after chemical cleavage.	Glycine	154-157	insulin like growth factor 1	Homo sapiens	129-134
11319794-4	2001	The collision-induced dissociation spectra obtained from the PRP-1 tryptic peptides and the synthetic peptides indicate that facile Gln-Gly cleavage occurs when an X-Gln-Gly-Y sequence is present in a peptide, where X is any amino acid and Y any amino acid other than Gly.	Glycine	170-173	opiorphin prepropeptide	Homo sapiens	61-66
11319794-4	2001	The collision-induced dissociation spectra obtained from the PRP-1 tryptic peptides and the synthetic peptides indicate that facile Gln-Gly cleavage occurs when an X-Gln-Gly-Y sequence is present in a peptide, where X is any amino acid and Y any amino acid other than Gly.	Glycine	170-173	opiorphin prepropeptide	Homo sapiens	61-66
11104832-5	2000	N-[2-[4-2,2-dimethylpropionyloxy) phenylsulfonylamino] benzoyl]? aminoacetic acid (ONO-5046), a specific neutrophil elastase inhibitor, which was developed as a low-molecular weight inhibitor, showed protective effects against various lung injuries.	Glycine	65-81	elastase, neutrophil expressed	Rattus norvegicus	105-124
11713985-4	2001	Expression of proCCK as a fusion protein to the prepro leader peptide of alpha-mating factor directed the protein through the secretory pathway and resulted in nanomolar concentrations of secreted glycine-extended CCK.	Glycine	197-204	cholecystokinin	Homo sapiens	17-20
11118382-10	2000	We found that the myristylation of the N-terminal glycine residue is essential for Gag release.	Glycine	50-57	Pr55	Human T-cell leukemia virus type I	83-86
11163984-6	2000	Gly-[3H]L-Pro uptake had a substantial active concentration-dependent component (Km of 0.39 +/- 0.02 mM, Vmax of 0.98 +/- 0.04 nmol min(-1) (mg protein)(-1).	Glycine	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
11209755-6	2000	The architecture of the substrate binding site of granzyme B appears to be designed to accommodate and cleave hexapeptides such as the sequence Ile-Glu-Thr-Asp-/Ser-Gly present in the activation site of pro-caspase-3, a proven physiological substrate of granzyme B.	Glycine	165-168	caspase 3	Homo sapiens	203-216
11280065-6	2001	Interestingly, Gly-437 in dhps along with Arg-59/Asn-108 in dhfr were associated with RI, RII and RIII resistance whereas Glu-540 was highly associated with only RII and RIII Fansidar resistance.	Glycine	15-18	deoxyhypusine synthase	Homo sapiens	26-30
11118328-1	2000	We describe the genes for three new glycine-rich antimicrobial peptides in Drosophila, two attacins (AttC and AttD) and one diptericin (DptB).	Glycine	36-43	Diptericin B	Drosophila melanogaster	136-140
11106434-1	2000	The activity and substrate specificity of D-amino acid aminotransferase (D-AAT) (EC 2.6.1.21) can be rationally modulated by replacing the loop core (P119-R120-P121) with glycine chains of different lengths: 1, 3, or 5 glycines.	Glycine	171-178	serpin family A member 1	Homo sapiens	75-78
11106434-1	2000	The activity and substrate specificity of D-amino acid aminotransferase (D-AAT) (EC 2.6.1.21) can be rationally modulated by replacing the loop core (P119-R120-P121) with glycine chains of different lengths: 1, 3, or 5 glycines.	Glycine	219-227	serpin family A member 1	Homo sapiens	75-78
11100732-3	2000	We previously found that the carboxy-terminal arginine of nascent Apg8 is removed by Apg4/Aut2 protease, leaving a glycine residue at the C terminus.	Glycine	115-122	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	66-70
11099414-2	2000	The pro-apoptotic protein BID underwent posttranslational (rather than classic cotranslational) N-myristoylation when cleavage by caspase 8 caused exposure of a glycine residue.	Glycine	161-168	BH3 interacting domain death agonist	Homo sapiens	26-29
11100732-3	2000	We previously found that the carboxy-terminal arginine of nascent Apg8 is removed by Apg4/Aut2 protease, leaving a glycine residue at the C terminus.	Glycine	115-122	cysteine protease ATG4	Saccharomyces cerevisiae S288C	90-94
11100732-6	2000	Apg8 is covalently conjugated to phosphatidylethanolamine through an amide bond between the C-terminal glycine and the amino group of phosphatidylethanolamine.	Glycine	103-110	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	0-4
11080374-5	2000	While most of the variation in the inhibition rates of thrombin could be accounted for by P2 Gly-to-Pro substitutions, for APC almost every residue had an effect on inhibition.	Glycine	93-96	coagulation factor II, thrombin	Homo sapiens	55-63
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase kinase 4	Homo sapiens	6-10
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase kinase 6	Homo sapiens	15-19
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase 14	Homo sapiens	145-151
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase 14	Homo sapiens	152-155
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase 13	Homo sapiens	177-182
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase 13	Homo sapiens	183-192
10942763-5	2000	Of the Gly-139 mutants investigated, only G139A catalyzes the NADPH-cytochrome P450 reductase-dependent oxidation of heme to biliverdin, but most of them exhibit a new H(2)O(2)-dependent guaiacol peroxidation activity.	Glycine	7-10	cytochrome p450 oxidoreductase	Homo sapiens	62-93
10913124-4	2000	Addition of a glycine to the Gly(274)-Gly(275) motif in GRP1 greatly increased its binding affinity for PtdIns(4,5)P(2) with little effect on its binding to PtdIns(3,4,5)P(3), while deletion of a single glycine in the corresponding triglycine motif of the ARNO PH domain markedly reduced its binding affinity for PtdIns(4,5)P(2) but not for PtdIns(3,4,5)P(3).	Glycine	14-21	cytohesin 3	Homo sapiens	56-60
11094174-0	2000	Rhodopsin gene codon 106 mutation (Gly-to-Arg) in a Japanese family with autosomal dominant retinitis pigmentosa.	Glycine	35-38	rhodopsin	Homo sapiens	0-9
10913124-4	2000	Addition of a glycine to the Gly(274)-Gly(275) motif in GRP1 greatly increased its binding affinity for PtdIns(4,5)P(2) with little effect on its binding to PtdIns(3,4,5)P(3), while deletion of a single glycine in the corresponding triglycine motif of the ARNO PH domain markedly reduced its binding affinity for PtdIns(4,5)P(2) but not for PtdIns(3,4,5)P(3).	Glycine	14-21	cytohesin 2	Homo sapiens	256-260
10913124-4	2000	Addition of a glycine to the Gly(274)-Gly(275) motif in GRP1 greatly increased its binding affinity for PtdIns(4,5)P(2) with little effect on its binding to PtdIns(3,4,5)P(3), while deletion of a single glycine in the corresponding triglycine motif of the ARNO PH domain markedly reduced its binding affinity for PtdIns(4,5)P(2) but not for PtdIns(3,4,5)P(3).	Glycine	29-32	cytohesin 3	Homo sapiens	56-60
10913124-4	2000	Addition of a glycine to the Gly(274)-Gly(275) motif in GRP1 greatly increased its binding affinity for PtdIns(4,5)P(2) with little effect on its binding to PtdIns(3,4,5)P(3), while deletion of a single glycine in the corresponding triglycine motif of the ARNO PH domain markedly reduced its binding affinity for PtdIns(4,5)P(2) but not for PtdIns(3,4,5)P(3).	Glycine	29-32	cytohesin 2	Homo sapiens	256-260
10913124-4	2000	Addition of a glycine to the Gly(274)-Gly(275) motif in GRP1 greatly increased its binding affinity for PtdIns(4,5)P(2) with little effect on its binding to PtdIns(3,4,5)P(3), while deletion of a single glycine in the corresponding triglycine motif of the ARNO PH domain markedly reduced its binding affinity for PtdIns(4,5)P(2) but not for PtdIns(3,4,5)P(3).	Glycine	38-41	cytohesin 3	Homo sapiens	56-60
10913124-4	2000	Addition of a glycine to the Gly(274)-Gly(275) motif in GRP1 greatly increased its binding affinity for PtdIns(4,5)P(2) with little effect on its binding to PtdIns(3,4,5)P(3), while deletion of a single glycine in the corresponding triglycine motif of the ARNO PH domain markedly reduced its binding affinity for PtdIns(4,5)P(2) but not for PtdIns(3,4,5)P(3).	Glycine	38-41	cytohesin 2	Homo sapiens	256-260
10913124-4	2000	Addition of a glycine to the Gly(274)-Gly(275) motif in GRP1 greatly increased its binding affinity for PtdIns(4,5)P(2) with little effect on its binding to PtdIns(3,4,5)P(3), while deletion of a single glycine in the corresponding triglycine motif of the ARNO PH domain markedly reduced its binding affinity for PtdIns(4,5)P(2) but not for PtdIns(3,4,5)P(3).	Glycine	203-210	cytohesin 3	Homo sapiens	56-60
11015226-10	2000	Clostripain activation was accompanied by the cleavage of the pro region to form mainly two activation products, Leu(30p)- and Gly(45p)-memapsin 2.	Glycine	127-130	beta-secretase 1	Homo sapiens	136-146
11029402-9	2000	Recombinant human MMP-2 cleaved calcitonin gene-related peptide (CGRP) specifically at the Gly(14)-Leu(15) peptide bond and reduced the vasodilatory potency of CGRP by 20-fold.	Glycine	91-94	calcitonin related polypeptide alpha	Homo sapiens	32-63
11029402-9	2000	Recombinant human MMP-2 cleaved calcitonin gene-related peptide (CGRP) specifically at the Gly(14)-Leu(15) peptide bond and reduced the vasodilatory potency of CGRP by 20-fold.	Glycine	91-94	calcitonin related polypeptide alpha	Homo sapiens	65-69
11015226-14	2000	Proteolytic removal of part of the pro-peptide at Leu(28p) or Gly(45p), which diminishes the affinity of the shortened pro-peptide to the active site, results in activated memapsin 2.	Glycine	62-65	beta-secretase 1	Homo sapiens	172-182
11029044-7	2000	Moreover, a point mutation at Gly-306 abrogates the ability of the Cbl Src homology domain 2 to induce these morphological changes.	Glycine	30-33	Cbl proto-oncogene	Canis lupus familiaris	67-70
11229371-5	2000	Peroxisome proliferators have been shown to activate Kupffer cells both in vitro and in vivo, and the use of Kupffer cell inhibitors such as methyl palmitate and dietary glycine have demonstrated that Kupffer cells are responsible for hepatocyte proliferation by mechanisms involve TNF-alpha.	Glycine	170-177	tumor necrosis factor	Homo sapiens	282-291
11011154-7	2000	Fibrinogen bound to purified alpha(5)beta(1) in a time-dependent, specific, and saturable manner in the presence of Mn(2+), and the binding was blocked completely by Arg-Gly-Asp (RGD)-containing peptides and by anti-alpha(5) and anti-alpha(5)beta(1) monoclonal antibodies.	Glycine	170-173	fibrinogen beta chain	Homo sapiens	0-10
11027708-6	2000	The uvh1-2 mutant allele carries a glycine--&gt;aspartate amino acid change that has been previously identified to produce a null allele of RAD1 in yeast.	Glycine	35-42	Restriction endonuclease, type II-like superfamily protein	Arabidopsis thaliana	4-8
10999946-0	2000	Glycine receptor beta subunits play a critical role in potentiation of glycine responses by ICS-205,930.	Glycine	71-78	glycine receptor beta	Homo sapiens	0-21
11027708-6	2000	The uvh1-2 mutant allele carries a glycine--&gt;aspartate amino acid change that has been previously identified to produce a null allele of RAD1 in yeast.	Glycine	35-42	ssDNA endodeoxyribonuclease RAD1	Saccharomyces cerevisiae S288C	140-144
11068099-2	2000	Endoproteinase Glu-C digestion combined with mass spectrometry and automated Edman degradation localized glycation to Gly(1) and Phe(1) of the insulin A- and B-chains, respectively.	Glycine	118-121	insulin	Homo sapiens	143-150
10982770-0	2000	Glycine-extended gastrin synergizes with gastrin 17 to stimulate acid secretion in gastrin-deficient mice.	Glycine	0-7	gastrin	Mus musculus	17-24
11033051-3	2000	Recent studies suggest that gastrin, in both its fully amidated and less processed forms (progastrin and glycine-extended gastrin), is also a growth factor for the gastrointestinal tract.	Glycine	105-112	gastrin	Mus musculus	28-35
10973830-8	2000	Binding occurred independently of homoribopolymer binding to the C-terminal arginine-glycine-rich region (RGG box), suggesting that FMRP may bind multiple RNAs simultaneously.	Glycine	85-92	fragile X messenger ribonucleoprotein 1	Homo sapiens	132-136
10947965-1	2000	We have determined that the mutation of the cysteine-230 residue to either glycine or serine in TRAIL (tumour necrosis factor-alpha-related apoptosis-inducing ligand) results in the formation of a structurally incompetent dimer and a consequent loss of apoptotic activity.	Glycine	75-82	TNF superfamily member 10	Homo sapiens	96-101
10947965-1	2000	We have determined that the mutation of the cysteine-230 residue to either glycine or serine in TRAIL (tumour necrosis factor-alpha-related apoptosis-inducing ligand) results in the formation of a structurally incompetent dimer and a consequent loss of apoptotic activity.	Glycine	75-82	TNF superfamily member 10	Homo sapiens	103-165
10978526-4	2000	Unlike other members of the NBC family, NBC4 has a unique glycine-rich region (amino acids 438-485).	Glycine	58-65	solute carrier family 4 member 5	Homo sapiens	40-44
11030562-4	2000	However, expression of a cDNA encoding a proinsulin-like molecule with deletion of threonine(B30) as a fusion protein with the S. cerevisiae alpha-factor prepro-peptide (leader), followed either by replacement of the human proinsulin C-peptide with a small C-peptide (e.g. AAK), or by direct fusion of lysine(B29) to glycine(A1), results in the efficient secretion of folded single-chain proinsulin-like molecules to the culture supernatant.	Glycine	317-324	insulin	Homo sapiens	41-51
10947972-7	2000	We find that the caspases show an unexpected degree of discrimination in the P(1)" position, with a general preference for small amino acid residues such as alanine, glycine and serine, with glycine being the preferred substituent.	Glycine	166-173	caspase 1	Homo sapiens	17-25
10947972-7	2000	We find that the caspases show an unexpected degree of discrimination in the P(1)" position, with a general preference for small amino acid residues such as alanine, glycine and serine, with glycine being the preferred substituent.	Glycine	191-198	caspase 1	Homo sapiens	17-25
11117265-3	2000	A mutant of pokeweed antiviral protein, PAPn, which has a single amino acid substitution (G75D), did not bind ribosomes efficiently, indicating that Gly-75 in the N-terminal domain is critical for the binding of PAP to ribosomes.	Glycine	149-152	light-induced protein, chloroplastic-like	Nicotiana tabacum	40-43
10960447-10	2000	Moreover, Bcl-2 protein levels in SECs were decreased 8 hours after VEGF deprivation, which was prevented almost completely by glycine.	Glycine	127-134	BCL2, apoptosis regulator	Rattus norvegicus	10-15
10938401-0	2000	Altered activity of MDR-reversing agents on KB3-1 cells transfected with Gly(185)--&gt;Val human P-glycoprotein.	Glycine	73-76	ATP binding cassette subfamily B member 1	Homo sapiens	97-111
10924333-0	2000	The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein (CRP2BP).	Glycine	18-25	lysine acetyltransferase 14	Homo sapiens	106-112
11877016-3	2000	Human vWF was purified from blood cryoprecipitate by glycine and NaCl precipitation and subsequent separation on sepharose 4B column.	Glycine	53-60	von Willebrand factor	Homo sapiens	6-9
10926853-4	2000	Here we report that the alpha-actinin-binding region of CRP, which we have mapped by using a combination of blot overlay and Western immunoblot techniques, is confined to an 18-residue sequence occurring within the protein"s N-terminal glycine-rich repeat.	Glycine	236-243	actinin alpha 1	Homo sapiens	24-37
11004581-5	2000	The efficiency of MPO inhibitors to prevent LDL damage increased in the series benzohydroxamic acid &lt; salicylhydroxamic acid &lt; 3-amino-1,2,4-triazole &lt; sodium azide &lt; potassium cyanide &lt; p-hydroxy-benzoic acid hydrazide, while for the HOCl traps the protective efficiency increased in the series glycine &lt; taurine &lt; methionine.	Glycine	311-318	myeloperoxidase	Homo sapiens	18-21
10801840-3	2000	Solid-phase syntheses of VIP analogs in which each amino acid has been changed to alanine (Ala scan) or glycine was achieved and each analog was tested for: (i) three-dimensional structure by ab initio molecular modeling; (ii) ability to inhibit (125)I-VIP binding (K(i)) and to stimulate adenylyl cyclase activity (EC(50)) in membranes from cell clones stably expressing human recombinant VPAC(1) or VPAC(2) receptor.	Glycine	104-111	vasoactive intestinal peptide	Homo sapiens	25-28
10926563-2	2000	Acute dietary glycine prevents mortality and blunts increases in serum tumor necrosis factor-alpha (TNF-alpha) following endotoxin in rats.	Glycine	14-21	tumor necrosis factor	Rattus norvegicus	71-98
10926563-2	2000	Acute dietary glycine prevents mortality and blunts increases in serum tumor necrosis factor-alpha (TNF-alpha) following endotoxin in rats.	Glycine	14-21	tumor necrosis factor	Rattus norvegicus	100-109
10937511-2	2000	OBJECTIVE: Insulin glargine (HOE 901, 21(A)-Gly-30(B)a-L-Arg-30(B)b-L-Arg human insulin) is a novel recombinant analog of human insulin with a shift in the isoelectric point producing a retarded absorption rate and an increased duration of action that closely mimics normal basal insulin secretion.	Glycine	44-47	insulin	Homo sapiens	11-18
10945617-9	2000	Analysis of the p53 cDNA from several focus-derived strains lacking p53 activity revealed that each contained the same mutation, an A to G transition at codon 215, resulting in a change from serine to glycine.	Glycine	201-208	tumor protein p53	Homo sapiens	16-19
10945617-9	2000	Analysis of the p53 cDNA from several focus-derived strains lacking p53 activity revealed that each contained the same mutation, an A to G transition at codon 215, resulting in a change from serine to glycine.	Glycine	201-208	tumor protein p53	Homo sapiens	68-71
10937511-2	2000	OBJECTIVE: Insulin glargine (HOE 901, 21(A)-Gly-30(B)a-L-Arg-30(B)b-L-Arg human insulin) is a novel recombinant analog of human insulin with a shift in the isoelectric point producing a retarded absorption rate and an increased duration of action that closely mimics normal basal insulin secretion.	Glycine	44-47	insulin	Homo sapiens	80-87
10937511-2	2000	OBJECTIVE: Insulin glargine (HOE 901, 21(A)-Gly-30(B)a-L-Arg-30(B)b-L-Arg human insulin) is a novel recombinant analog of human insulin with a shift in the isoelectric point producing a retarded absorption rate and an increased duration of action that closely mimics normal basal insulin secretion.	Glycine	44-47	insulin	Homo sapiens	128-135
10937511-2	2000	OBJECTIVE: Insulin glargine (HOE 901, 21(A)-Gly-30(B)a-L-Arg-30(B)b-L-Arg human insulin) is a novel recombinant analog of human insulin with a shift in the isoelectric point producing a retarded absorption rate and an increased duration of action that closely mimics normal basal insulin secretion.	Glycine	44-47	insulin	Homo sapiens	128-135
10916091-6	2000	Next, using cultured human mesangial cells, we investigated the role of Gly-Alb and/or HG on the gene and protein expression of MCP-1.	Glycine	72-75	albumin	Homo sapiens	76-79
10971626-6	2000	It is concluded that gp120 acts as a very potent agonist at the glycine site of NMDA receptors sited on CCK- and SRIF-releasing nerve endings; the protein is able to activate the receptor channel in the absence of glutamate.	Glycine	64-71	cholecystokinin	Homo sapiens	104-107
10971113-0	2000	Occurrence of IgE antibody-recognizing N-linked glycan moiety of a soybean allergen, Gly m Bd 28K.	Glycine	85-88	immunoglobulin heavy constant epsilon	Homo sapiens	14-17
10971113-2	2000	Gly m Bd 28K, a soybean allergen, was a glycoprotein with glycan moieties, which are supposed to be the Man(3)GlcNAc(2) backbone with the beta1--&gt;2 xylose and alpha1--&gt;3 fucose branches.	Glycine	0-3	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	138-143
10971113-3	2000	The purpose of the present study was to examine the IgE-binding ability of the glycan moiety of Gly m Bd 28K in the binding reaction with patients" sera.	Glycine	96-99	immunoglobulin heavy constant epsilon	Homo sapiens	52-55
10971113-7	2000	The binding of patients" IgE antibodies with their glycan moiety was examined by an immunostaining technique using the glycopeptide and its deglycosylated peptide derived from Gly m Bd 28K.	Glycine	176-179	immunoglobulin heavy constant epsilon	Homo sapiens	25-28
10971113-11	2000	CONCLUSIONS: The specific IgE antibodies recognizing the N-linked glycan moieties of Gly m Bd 28K and other glycoproteins with homologous glycan moieties occur in the sera of soybean-sensitive patients.	Glycine	85-88	immunoglobulin heavy constant epsilon	Homo sapiens	26-29
10971113-12	2000	It was indicated that the N-linked glycan moieties such as that of Gly m Bd 28K may be one of the common IgE-reactive determinants distributed in various plant food proteins.	Glycine	67-70	immunoglobulin heavy constant epsilon	Homo sapiens	105-108
10953028-5	2000	APC(min-/+) mice overexpressing one of the alternatively processed forms of gastrin, glycine-extended gastrin, show a significant increase in polyp number.	Glycine	85-92	gastrin	Mus musculus	76-83
10953028-5	2000	APC(min-/+) mice overexpressing one of the alternatively processed forms of gastrin, glycine-extended gastrin, show a significant increase in polyp number.	Glycine	85-92	gastrin	Mus musculus	102-109
10806190-9	2000	The interaction between yUbc9 and SUMO-1 was abolished by deleting the C-terminal Gly residue of SUMO-1, which is reportedly required for the formation of Ubc9-SUMO-1 thioester linkage.	Glycine	82-85	E2 SUMO-conjugating protein UBC9	Saccharomyces cerevisiae S288C	24-29
10806190-9	2000	The interaction between yUbc9 and SUMO-1 was abolished by deleting the C-terminal Gly residue of SUMO-1, which is reportedly required for the formation of Ubc9-SUMO-1 thioester linkage.	Glycine	82-85	small ubiquitin-like modifier 1	Mus musculus	34-40
10806190-9	2000	The interaction between yUbc9 and SUMO-1 was abolished by deleting the C-terminal Gly residue of SUMO-1, which is reportedly required for the formation of Ubc9-SUMO-1 thioester linkage.	Glycine	82-85	small ubiquitin-like modifier 1	Mus musculus	97-103
10806190-9	2000	The interaction between yUbc9 and SUMO-1 was abolished by deleting the C-terminal Gly residue of SUMO-1, which is reportedly required for the formation of Ubc9-SUMO-1 thioester linkage.	Glycine	82-85	small ubiquitin-like modifier 1	Mus musculus	97-103
10806190-10	2000	The interaction of Wrn and SUMO-1 was also abolished by deleting the Gly residue, indicating that the interaction of Wrn and SUMO-1 is mediated by yUbc9 in the two-hybrid system.	Glycine	69-72	Werner syndrome RecQ like helicase	Mus musculus	19-22
10806190-10	2000	The interaction of Wrn and SUMO-1 was also abolished by deleting the Gly residue, indicating that the interaction of Wrn and SUMO-1 is mediated by yUbc9 in the two-hybrid system.	Glycine	69-72	small ubiquitin-like modifier 1	Mus musculus	27-33
10806190-10	2000	The interaction of Wrn and SUMO-1 was also abolished by deleting the Gly residue, indicating that the interaction of Wrn and SUMO-1 is mediated by yUbc9 in the two-hybrid system.	Glycine	69-72	Werner syndrome RecQ like helicase	Mus musculus	117-120
10806190-10	2000	The interaction of Wrn and SUMO-1 was also abolished by deleting the Gly residue, indicating that the interaction of Wrn and SUMO-1 is mediated by yUbc9 in the two-hybrid system.	Glycine	69-72	small ubiquitin-like modifier 1	Mus musculus	125-131
10806190-10	2000	The interaction of Wrn and SUMO-1 was also abolished by deleting the Gly residue, indicating that the interaction of Wrn and SUMO-1 is mediated by yUbc9 in the two-hybrid system.	Glycine	69-72	E2 SUMO-conjugating protein UBC9	Saccharomyces cerevisiae S288C	147-152
10728833-10	2000	The amino-terminal sequence of LM-PLA2 (previously reported) indicates an aspartic acid residue located at position 49, together with other conserved amino acids present in the Asp-49 phospholipases, such as Tyr-28, Gly-30, Gly-32, His-48.	Glycine	216-219	phospholipase A2, group V	Mus musculus	34-38
10801785-3	2000	Thrombin activates the Factor XIII a(2) dimer by cleaving the Factor XIII activation peptide segment at the Arg(37)-Gly(38) peptide bond.	Glycine	116-119	coagulation factor II, thrombin	Homo sapiens	0-8
10880389-0	2000	Fibrinogen brescia: hepatic endoplasmic reticulum storage and hypofibrinogenemia because of a gamma284 Gly-->Arg mutation.	Glycine	103-106	fibrinogen beta chain	Homo sapiens	0-10
10865171-4	2000	OL- and serine-glycine-containing lipid (SGL)-induced TNF-alpha production in J774.1 and RAW 264.7 cells required serum.	Glycine	15-22	tumor necrosis factor	Mus musculus	54-63
10947204-4	2000	Only the first patient had alterations in the MMSDH coding region, revealing homozygosity for a 1336G > A transversion, which leads to substitution of arginine for highly conserved glycine at amino acid 446.	Glycine	181-188	aldehyde dehydrogenase 6 family member A1	Homo sapiens	46-51
10936447-0	2000	A disease-associated glycine substitution in BP180 (type XVII collagen) leads to a local destabilization of the major collagen triple helix.	Glycine	21-28	collagen type XVII alpha 1 chain	Homo sapiens	45-50
10936447-3	2000	Like the null mutations, a glycine substitution (G627V) within the longest BP180 collagenous domain (COL15) is also associated with the recessive skin disease; however, unlike the null mutations, this glycine substitution appears to act in a dominant fashion to give rise to a novel form of random pitting dental enamel hypoplasia.	Glycine	27-34	collagen type XVII alpha 1 chain	Homo sapiens	75-80
10936447-3	2000	Like the null mutations, a glycine substitution (G627V) within the longest BP180 collagenous domain (COL15) is also associated with the recessive skin disease; however, unlike the null mutations, this glycine substitution appears to act in a dominant fashion to give rise to a novel form of random pitting dental enamel hypoplasia.	Glycine	201-208	collagen type XVII alpha 1 chain	Homo sapiens	75-80
10873678-1	2000	Genetic polyymorphisms that result in three amino acid changes in FcepsilonRI beta chain (Ile(181)--&gt;Leu, Val(183)--&gt;Leu, and Glu(237)--&gt;Gly) have been identified as candidates that associate with allergic disorders such as atopy and asthma.	Glycine	146-149	Fc receptor, IgE, high affinity I, gamma polypeptide	Mus musculus	66-77
10871321-7	2000	BK1-5 (Arg-Pro-Pro-Gly-Phe), the 1-to-5 amino acid fragment of bradykinin, was identified as a major stable plasma metabolite of bradykinin.	Glycine	19-22	kininogen 1	Homo sapiens	63-73
10871321-7	2000	BK1-5 (Arg-Pro-Pro-Gly-Phe), the 1-to-5 amino acid fragment of bradykinin, was identified as a major stable plasma metabolite of bradykinin.	Glycine	19-22	kininogen 1	Homo sapiens	129-139
10860934-2	2000	The GLYT1b subtype of glycine transporters is expressed in similar regions of the brain as the excitatory N-methyl-D-aspartate receptors and has been postulated to regulate glycine concentrations within excitatory synapses.	Glycine	22-29	solute carrier family 6 member 9 S homeolog	Xenopus laevis	4-10
10728833-10	2000	The amino-terminal sequence of LM-PLA2 (previously reported) indicates an aspartic acid residue located at position 49, together with other conserved amino acids present in the Asp-49 phospholipases, such as Tyr-28, Gly-30, Gly-32, His-48.	Glycine	224-227	phospholipase A2, group V	Mus musculus	34-38
10849437-1	2000	Mammalian thioredoxin reductases (TrxR) are dimers homologous to glutathione reductase with a selenocysteine (SeCys) residue in the conserved C-terminal sequence -Gly-Cys-SeCys-Gly.	Glycine	163-166	thioredoxin 1	Rattus norvegicus	10-21
10849437-1	2000	Mammalian thioredoxin reductases (TrxR) are dimers homologous to glutathione reductase with a selenocysteine (SeCys) residue in the conserved C-terminal sequence -Gly-Cys-SeCys-Gly.	Glycine	177-180	thioredoxin 1	Rattus norvegicus	10-21
10856217-1	2000	Mutations introduced into human growth hormone (hGH) (Thr175 --&gt; Gly-hGH) and the extracellular domain of the hGH receptor (Trp104 --&gt; Gly-hGHbp) created a cavity at the protein-protein interface that resulted in binding affinity being reduced by a factor of 10(6).	Glycine	68-71	growth hormone 1	Homo sapiens	32-46
10898109-6	2000	The increase in the Km, which is equivalent to a four-fold reduction in the affinity of the variant hNET for its natural substrate norepinephrine, indicates that the glycine in position 478 is part of a substrate recognition domain.	Glycine	166-173	solute carrier family 6 member 2	Homo sapiens	100-104
10839997-3	2000	To understand the molecular basis of the high phosphatidylcholine specificity of hVPLA(2), we mutated several residues (Gly-53, Glu-56 and Glu-57) that might be involved in interaction with an active-site-bound phospholipid molecule.	Glycine	120-123	phospholipase A2 group V	Homo sapiens	81-89
10839988-2	2000	The amino acid sequences of the stimulator of HIV-1 TAR (Tat-responsive element) RNA-binding protein (SRB) and fibronectin also show the presence of the internal -Gly-Arg-Gly- (-GRG-) sequence, which is potentially methylatable by the methyltransferase.	Glycine	163-166	fibronectin 1	Homo sapiens	111-122
10841760-9	2000	Although the insertion of a Gly residue (absent in arrestins but present in the putative phosphate-binding site of ataxin-7) disrupts the function of visual arrestin-ataxin-7 chimera, it enhances the function of beta-arrestin-ataxin-7 chimera.	Glycine	28-31	ataxin 7	Homo sapiens	166-174
10841760-9	2000	Although the insertion of a Gly residue (absent in arrestins but present in the putative phosphate-binding site of ataxin-7) disrupts the function of visual arrestin-ataxin-7 chimera, it enhances the function of beta-arrestin-ataxin-7 chimera.	Glycine	28-31	ataxin 7	Homo sapiens	115-123
10871840-5	2000	The insulin stimulated or Src/Fyn-mediated tyrosine phosphorylation in vivo was significantly reduced when Grb10 tyrosine 67 was changed to glycine.	Glycine	140-147	insulin	Homo sapiens	4-11
10841760-9	2000	Although the insertion of a Gly residue (absent in arrestins but present in the putative phosphate-binding site of ataxin-7) disrupts the function of visual arrestin-ataxin-7 chimera, it enhances the function of beta-arrestin-ataxin-7 chimera.	Glycine	28-31	ataxin 7	Homo sapiens	166-174
10871840-5	2000	The insulin stimulated or Src/Fyn-mediated tyrosine phosphorylation in vivo was significantly reduced when Grb10 tyrosine 67 was changed to glycine.	Glycine	140-147	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	26-29
10842714-2	2000	The SAA1 exon 4 was amplified by PCR and treated with Nco I. Sequencing of PCR products from genomic DNA of individuals who were heterozygous for the Nco I site revealed GGT (Gly) and GAT (Asp) at the position 72.	Glycine	175-178	serum amyloid A1	Homo sapiens	4-8
10845886-8	2000	Increased thrombus formation was observed when the Arg-Gly-Gly-Ser-vWF, which does not interact with alphaIIb-beta3, was added to vWD blood and perfused at 2600 s(-1).	Glycine	55-58	von Willebrand factor	Homo sapiens	67-70
10845886-8	2000	Increased thrombus formation was observed when the Arg-Gly-Gly-Ser-vWF, which does not interact with alphaIIb-beta3, was added to vWD blood and perfused at 2600 s(-1).	Glycine	59-62	von Willebrand factor	Homo sapiens	67-70
10886333-3	2000	Glycine-triggered Ca2+ influx in OP cells actually results from an initial depolarization that is the consequence of the activation of both the ionotropic glycine receptor (GlyR) and Na+-dependent transporters, most probably the glycine transporters 1 (GLYT1) and/or 2 (GLYT2) which are colocalized in these cells.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	253-258
10873097-4	2000	An A--&gt;G transition at codon 149 resulted in amino acid substitution from aspartate to glycine in the proliferating cell nuclear antigen binding COOH-terminal domain of p21(Waf1/Cip1) that may affect PCNA-p21(Waf1/Cip1) interactions, thereby affecting regulation of cellular proliferation, and may increase susceptibility for development of cancer.	Glycine	90-97	cyclin dependent kinase inhibitor 1A	Homo sapiens	172-175
10873097-4	2000	An A--&gt;G transition at codon 149 resulted in amino acid substitution from aspartate to glycine in the proliferating cell nuclear antigen binding COOH-terminal domain of p21(Waf1/Cip1) that may affect PCNA-p21(Waf1/Cip1) interactions, thereby affecting regulation of cellular proliferation, and may increase susceptibility for development of cancer.	Glycine	90-97	cyclin dependent kinase inhibitor 1A	Homo sapiens	176-180
10873097-4	2000	An A--&gt;G transition at codon 149 resulted in amino acid substitution from aspartate to glycine in the proliferating cell nuclear antigen binding COOH-terminal domain of p21(Waf1/Cip1) that may affect PCNA-p21(Waf1/Cip1) interactions, thereby affecting regulation of cellular proliferation, and may increase susceptibility for development of cancer.	Glycine	90-97	cyclin dependent kinase inhibitor 1A	Homo sapiens	181-185
10873097-4	2000	An A--&gt;G transition at codon 149 resulted in amino acid substitution from aspartate to glycine in the proliferating cell nuclear antigen binding COOH-terminal domain of p21(Waf1/Cip1) that may affect PCNA-p21(Waf1/Cip1) interactions, thereby affecting regulation of cellular proliferation, and may increase susceptibility for development of cancer.	Glycine	90-97	cyclin dependent kinase inhibitor 1A	Homo sapiens	208-211
10873097-4	2000	An A--&gt;G transition at codon 149 resulted in amino acid substitution from aspartate to glycine in the proliferating cell nuclear antigen binding COOH-terminal domain of p21(Waf1/Cip1) that may affect PCNA-p21(Waf1/Cip1) interactions, thereby affecting regulation of cellular proliferation, and may increase susceptibility for development of cancer.	Glycine	90-97	cyclin dependent kinase inhibitor 1A	Homo sapiens	212-216
10873097-4	2000	An A--&gt;G transition at codon 149 resulted in amino acid substitution from aspartate to glycine in the proliferating cell nuclear antigen binding COOH-terminal domain of p21(Waf1/Cip1) that may affect PCNA-p21(Waf1/Cip1) interactions, thereby affecting regulation of cellular proliferation, and may increase susceptibility for development of cancer.	Glycine	90-97	cyclin dependent kinase inhibitor 1A	Homo sapiens	217-221
10822163-4	2000	Glycine levels in vivo are regulated by the actions of glycine (GLYT1) transporters.	Glycine	0-7	solute carrier family 6 member 9	Homo sapiens	64-69
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	226-229
10916182-0	2000	Homozygous and heterozygous gly-188-Arg mutation of the rhodopsin gene in a family with autosomal dominant retinitis pigmentosa.	Glycine	28-31	rhodopsin	Homo sapiens	56-65
10864042-3	2000	To identify Gar1p functional partners, we screened for mutations that are synthetically lethal with a gar1 mutant allele encoding a Gar1p mutant protein lacking its two glycine/arginine-rich (GAR) domains.	Glycine	169-176	H/ACA snoRNP pseudouridylase subunit GAR1	Saccharomyces cerevisiae S288C	102-106
10811859-3	2000	However, EBNA1 is invisible to CD8(+) cytotoxic T lymphocytes because its Gly/Ala repeat domain prevents proteasome-dependent processing for presentation on major histocompatibility complex (MHC) class I.	Glycine	74-77	EBNA-1	Human gammaherpesvirus 4	9-14
10777749-7	2000	Proteolysis of MgATP-actin, but not CaATP-actin, at Gly(46) on subdomain 2 is &gt;12 times faster when Tbeta(4) is bound.	Glycine	52-55	thymosin beta 4 X-linked	Homo sapiens	103-111
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	234-237
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	234-237
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	249-253
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	234-237
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	234-237
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	234-237
10780999-7	2000	The K(i)s for a series of glycine site ligands with diverse chemical structures were also determined for the inhibition of [(3)H]-MDL105,519 binding to NR1-1a/NR2A receptors.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	152-155
10780999-7	2000	The K(i)s for a series of glycine site ligands with diverse chemical structures were also determined for the inhibition of [(3)H]-MDL105,519 binding to NR1-1a/NR2A receptors.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	159-163
10780999-9	2000	It is suggested that glycine site antagonists may be divided into two classes based on their ability to distinguish between NR1 and NR1/NR2 receptors with respect to binding curve characteristics.	Glycine	21-28	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	124-127
10780999-9	2000	It is suggested that glycine site antagonists may be divided into two classes based on their ability to distinguish between NR1 and NR1/NR2 receptors with respect to binding curve characteristics.	Glycine	21-28	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	132-135
10853768-4	2000	The nucleotide sequence of the tobacco cob gene was determined and found to predict highly conserved glycine and phenylalanine residues that are associated with sensitivity to antimycin A and myxothiazol, respectively.	Glycine	101-108	cob	Nicotiana tabacum	39-42
10807697-9	2000	The fact that the mutation resides within a so called "non-lethal" region of the alpha2(I) collagen chain supports a regional model in phenotypic severity for alpha2(I) collagen mutations, in which the phenotype is determined primarily by the nature of the collagen domain rather than the type of glycine substitution involved.	Glycine	297-304	collagen type I alpha 2 chain	Homo sapiens	81-99
10834423-2	2000	OBJECTIVE: Insulin glargine (21A-Gly-30Ba-L-Arg-30Bb-L-Arg-human insulin) is a biosynthetic insulin analog with a prolonged duration of action compared with NPH human insulin.	Glycine	33-36	insulin	Homo sapiens	11-18
10807697-9	2000	The fact that the mutation resides within a so called "non-lethal" region of the alpha2(I) collagen chain supports a regional model in phenotypic severity for alpha2(I) collagen mutations, in which the phenotype is determined primarily by the nature of the collagen domain rather than the type of glycine substitution involved.	Glycine	297-304	collagen type I alpha 2 chain	Homo sapiens	159-177
10753918-7	2000	By contrast, truncation at Gly(359) created a dominant-negative mutant that inhibited ligand-induced cell death and activation of NF-kappaB p50/p65 heterodimers.	Glycine	27-30	nuclear factor kappa B subunit 1	Homo sapiens	130-143
10777573-5	2000	Each of the vWF residues Tyr(565), Glu(596), and Lys(599) proved to be strictly required for A1 domain function, which, in agreement with previous findings, was also dependent on Gly(561).	Glycine	179-182	von Willebrand factor	Homo sapiens	12-15
10756111-1	2000	Glycine N-methyltransferase (S-adenosyl-l-methionine: glycine methyltransferase, EC 2.1.1.20; GNMT) catalyzes the AdoMet-dependent methylation of glycine to form sarcosine (N-methylglycine).	Glycine	54-61	glycine N-methyltransferase	Homo sapiens	0-27
10756111-1	2000	Glycine N-methyltransferase (S-adenosyl-l-methionine: glycine methyltransferase, EC 2.1.1.20; GNMT) catalyzes the AdoMet-dependent methylation of glycine to form sarcosine (N-methylglycine).	Glycine	54-61	glycine N-methyltransferase	Homo sapiens	94-98
10775416-5	2000	A met7 gly1 strain is auxotrophic for glycine when grown on glucose but prototrophic when grown on glycerol.	Glycine	38-45	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	7-11
10775416-9	2000	All the genes providing cytoplasmic folylpolyglutamate synthetase complemented the methionine auxotrophy as well as the synthetic lethality of the shm2 strain and the synthetic glycine auxotrophy of the gly1 strain.	Glycine	177-184	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	203-207
10785511-3	2000	BSP contains an Arg-Gly-Asp (RGD) motif found in other adhesive molecules that interact with cellular integrins.	Glycine	20-23	integrin binding sialoprotein	Homo sapiens	0-3
10698201-6	2000	Subsequent site-directed mutagenesis showed that glycine 20 in TM6 of the Mel1a receptor occupies an important position in the binding site.	Glycine	49-56	melatonin receptor 1A	Homo sapiens	74-88
10777665-4	2000	Ngef contains a translated trinucleotide repeat, a polyglutamic acid stretch interrupted by a glycine.	Glycine	94-101	neuronal guanine nucleotide exchange factor	Homo sapiens	0-4
10753725-2	2000	After expression in Escherichia coli as single-chain variable domains (scFv) with glycine-serine linker sequences, both scFv bound CPV capsids with the same specificity as the intact IgG, but with 10- to 20-fold lower avidity.	Glycine	82-89	immunglobulin heavy chain variable region	Homo sapiens	71-75
10753725-2	2000	After expression in Escherichia coli as single-chain variable domains (scFv) with glycine-serine linker sequences, both scFv bound CPV capsids with the same specificity as the intact IgG, but with 10- to 20-fold lower avidity.	Glycine	82-89	immunglobulin heavy chain variable region	Homo sapiens	120-124
10694742-5	2000	The predicted amino acid sequence of rainbow trout Vasa contained eight consensus sequences for the DEAD protein family and five arginine-glycine-glycine repeats, a common character of known Vasa homologues.	Glycine	138-145	probable ATP-dependent RNA helicase DDX4	Oncorhynchus mykiss	51-55
10749988-2	2000	Transgenic mice over- expressing a mutated form of human SOD1 containing a Gly--&gt;Ala substitution at position 93 (SOD1(G93A)) develop a severe, progressive motoneuron disease.	Glycine	75-78	superoxide dismutase 1	Homo sapiens	57-61
10749988-2	2000	Transgenic mice over- expressing a mutated form of human SOD1 containing a Gly--&gt;Ala substitution at position 93 (SOD1(G93A)) develop a severe, progressive motoneuron disease.	Glycine	75-78	superoxide dismutase 1	Homo sapiens	117-121
10712199-2	2000	The mutant proteins have shown an expanded polyglutamine tract in SCA1, SCA2, MJD/SCA3, SCA6, SCA7, and DRPLA; a glycine-to-arginine substitution was found in SCA6 as well.	Glycine	113-120	ataxin 1	Homo sapiens	66-70
10683321-5	2000	A two-amino-acid change, from 79-proline-glycine-80 to 79-histidine-arginine-80, confers on the human Cyclin T1 the ability to cooperate with eTat in transcriptional activation.	Glycine	41-48	cyclin T1	Homo sapiens	102-111
10698962-1	2000	Recently, it was demonstrated that liver injury and TNF-alpha production as a result of endotoxin (lipopolysaccharide, LPS) were attenuated by feeding animals a diet enriched with glycine.	Glycine	180-187	tumor necrosis factor	Rattus norvegicus	52-61
10699284-1	2000	In recent years, major progress has been made in the design and synthesis of fibrinogen antagonists, which are peptidomimetic Arg-Gly-Asp (RGD) analogs.	Glycine	130-133	fibrinogen beta chain	Homo sapiens	77-87
10788533-6	2000	Of the p53 functional mutations, a substitution of Gly at amino acid residue 245 to Asp (G245D) was identified in two patients in three subclones.	Glycine	51-54	tumor protein p53	Homo sapiens	7-10
10648402-2	2000	The vWf-binding site on GP Ib-IX-V is within the N-terminal 282 residues of GP Ibalpha, which consist of an N-terminal flanking sequence (His-1-Ile-35), 7 leucine-rich repeats (Leu-36-Ala-200), a C-terminal flank (Phe-201-Gly-268), and a sulfated tyrosine sequence (Asp-269-Glu-282).	Glycine	222-225	von Willebrand factor	Homo sapiens	4-7
10677296-3	2000	In one family with OSMED, a homozygous Gly-->Arg substitution has been described in COL11A2, which codes for the alpha2 chain of type XI collagen.	Glycine	39-42	glycoprotein hormone subunit alpha 2	Homo sapiens	113-119
10652299-6	2000	These findings indicate that HMW FGF-2, with the presence of five or more dimethylated Gly-Arg-Gly repeats, contains an RGG box-like domain, which may be important for protein-protein and/or protein-RNA interactions.	Glycine	87-90	fibroblast growth factor 2	Homo sapiens	33-38
10652299-6	2000	These findings indicate that HMW FGF-2, with the presence of five or more dimethylated Gly-Arg-Gly repeats, contains an RGG box-like domain, which may be important for protein-protein and/or protein-RNA interactions.	Glycine	95-98	fibroblast growth factor 2	Homo sapiens	33-38
10648407-7	2000	Although dansyl-Glu-Gly-Arg-chloromethyl ketone inactivated-F. IXa inhibited the clotting activity of F.IXa, plasmin-treated F.IX did not.	Glycine	20-23	coagulation factor IX	Homo sapiens	102-107
10641038-0	2000	Glycine metabolism in Candida albicans: characterization of the serine hydroxymethyltransferase (SHM1, SHM2) and threonine aldolase (GLY1) genes.	Glycine	0-7	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	133-137
10683205-0	2000	Differential effects of ethanol on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters.	Glycine	35-42	solute carrier family 6 member 9	Homo sapiens	78-83
10620501-5	2000	To promote the independent folding of the two proteins in the chimaeric toxin, a linear flexible peptide, Gly-Gly-Gly-Gly-Ser, was inserted between the toxin and the ligand to generate restrictocin-linker-anti-TFR(scFv) and anti-TFR(scFv)-linker-restrictocin.	Glycine	106-109	immunglobulin heavy chain variable region	Homo sapiens	214-218
10620501-5	2000	To promote the independent folding of the two proteins in the chimaeric toxin, a linear flexible peptide, Gly-Gly-Gly-Gly-Ser, was inserted between the toxin and the ligand to generate restrictocin-linker-anti-TFR(scFv) and anti-TFR(scFv)-linker-restrictocin.	Glycine	106-109	immunglobulin heavy chain variable region	Homo sapiens	233-237
10664521-6	2000	Analysis of germline DNA in the proband showed a missense mutation (GGC--&gt;GAC) at codon 305 in exon 7 of the MEN1 gene that predicts an amino acid change from glycine to aspartic acid (G305D).	Glycine	162-169	menin 1	Homo sapiens	112-116
10667916-3	2000	The staining of HeLa cells expressing Gly(-) P-gp (91, 94, and 99N--&gt;Q), with P-gp specific monoclonal antibodies, MRK-16, UIC2 and 4E3 revealed a 40 to 50% lower cell-surface expression of mutant P-gp compared to the wild-type protein.	Glycine	38-41	ATP binding cassette subfamily B member 1	Homo sapiens	45-49
10667916-4	2000	The transport function of Gly(-) P-gp, assessed using a variety of fluorescent compounds indicated that the substrate specificity of the pump was not affected by the lack of glycosylation.	Glycine	26-29	ATP binding cassette subfamily B member 1	Homo sapiens	33-37
10667916-7	2000	(35)S-Methionine/cysteine pulse-chase studies revealed a reduced incorporation of (35)S-methionine/cysteine in full length Gly(-) P-gp compared to wild-type protein, but the half-life ( approximately 3 hr) of mutant P-gp was essentially unaltered.	Glycine	123-126	ATP binding cassette subfamily B member 1	Homo sapiens	130-134
10656678-4	2000	The resultant amino acid substitution from aspartate to glycine may have vital implication in PCNA mediated cell cycle regulation by p21(waf1/cip1).	Glycine	56-63	cyclin dependent kinase inhibitor 1A	Homo sapiens	133-146
10639097-8	2000	Each of the mutants desensitized more slowly than the WT 5-HT3A receptor, with the arginine and glycine mutations exhibiting the greatest effect (5-fold reduction).	Glycine	96-103	5-hydroxytryptamine receptor 3A	Homo sapiens	57-63
10602121-4	2000	Mutation analysis by means of RNase cleavage and direct sequencing of reverse transcription-polymerase chain reaction products showed in both the presence of a heterozygous G1489E [correction] mutation in the COL5A1 gene, which represents the first report of a glycine substitution in the main triple-helical region of alpha1(V) collagen.	Glycine	261-268	collagen type V alpha 1 chain	Homo sapiens	209-215
11920197-2	2000	The current study was designed to examine the availability of reduced glutathione precursors (glutamate, cysteine, glycine and possibly glutamine) together with the activity of the main transport pathways for their uptake (system ASC for cysteine and glycine; system gly for glycine).	Glycine	251-258	PYD and CARD domain containing	Homo sapiens	230-233
10694221-0	2000	Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters.	Glycine	66-73	solute carrier family 6 member 9	Homo sapiens	109-114
10644547-5	2000	The slope of the disappearance curves for both GLP-2-(1-33) and [Gly(2)]GLP-2 were significantly reduced in nephrectomized compared with non-nephrectomized rats (P &lt; 0.01).	Glycine	65-68	mast cell protease 10	Rattus norvegicus	72-77
11330044-1	2000	Glyoxylate is an immediate precursor of oxalate, but in its metabolism the conversion into glycine catalyzed by serine:pyruvate/alanine:glyoxylate aminotransferase (SPT/AGT) appears to be the main route.	Glycine	91-98	angiotensinogen	Homo sapiens	169-172
11920197-2	2000	The current study was designed to examine the availability of reduced glutathione precursors (glutamate, cysteine, glycine and possibly glutamine) together with the activity of the main transport pathways for their uptake (system ASC for cysteine and glycine; system gly for glycine).	Glycine	251-258	PYD and CARD domain containing	Homo sapiens	230-233
11920197-5	2000	The activity of system ASC was increased in HbS cells (both transport capacity and affinity were elevated for serine transport; transport capacity only for glycine).	Glycine	156-163	PYD and CARD domain containing	Homo sapiens	23-26
11920197-9	2000	Staurosporine (5 microM) inhibited O(2)-stimulated glycine transport through system ASC.	Glycine	51-58	PYD and CARD domain containing	Homo sapiens	84-87
10984130-10	2000	We concluded that glycine protects myeloperoxidase against hypochlorous acid-induced self-destruction.	Glycine	18-25	myeloperoxidase	Homo sapiens	35-50
11156700-8	2000	Therefore, peroxisomal localization of SPT/AGT may be indispensable for herbivores to convert the glyoxylate formed in peroxisomes into glycine in situ rather than forming oxalate.	Glycine	136-143	angiotensinogen	Homo sapiens	43-46
10759029-5	2000	Mutational analysis of the corresponding peptide LDVPPALADFIHQQR by glycine-walk followed by immunodetection of the resulting peptides indicated that amino acids 234, 237, 240, and 241 of the PM/Scl-100 autoantigen are essential for binding of the corresponding antibodies.	Glycine	68-75	exosome component 10	Homo sapiens	192-202
12845743-5	2000	These results showed that CL could enhance NMDA receptor mediated current to increase [Ca2+]i of neurons by acting on Gly site, thereby inducing epilepsy.	Glycine	118-121	carbonic anhydrase 2	Rattus norvegicus	87-90
10718634-1	2000	Myristoylation refers to the co-translational addition of a myristoyl group to an amino-terminal glycine residue of a protein by an ubiquitously distributed enzyme myristoyl-CoA:protein N-myristoyltransferase (NMT, EC 2.3.1.97).	Glycine	97-104	N-myristoyltransferase 1	Homo sapiens	186-208
10718634-1	2000	Myristoylation refers to the co-translational addition of a myristoyl group to an amino-terminal glycine residue of a protein by an ubiquitously distributed enzyme myristoyl-CoA:protein N-myristoyltransferase (NMT, EC 2.3.1.97).	Glycine	97-104	N-myristoyltransferase 1	Homo sapiens	210-213
11389540-7	2000	In support to this assumption, human mutant p53 (Gly(245)--&gt;Ser) was shown to bind to repetitive DNA elements in vivo that might be part of MAR elements.	Glycine	49-52	tumor protein p53	Homo sapiens	44-47
10954048-4	2000	These results suggest that the hippocampal histaminergic activity via histamine H1 receptor is necessary for normal working memory processes and that the septohippocampal cholinergic activation and positive modulation of the NMDA receptor/channel through activation of the glycine site can alleviate dysfunction of hippocampal histamine H1 receptor-mediated neurotransmission involved in working memory function.	Glycine	273-280	histamine receptor H 1	Rattus norvegicus	327-348
12058195-1	2000	In the insulin structural motif n1-Cys-Gly-X10-Cys-n2-Cys-Cys-X3-Cys-X8-Cys-n3, there are seven absolutely conserved amino acid residues, and the only Gly is at position B8.	Glycine	39-42	insulin	Homo sapiens	7-14
11056959-0	2000	Effect of glycine on plasma levels of glucose and insulin in healthy volunteers.	Glycine	10-17	insulin	Homo sapiens	50-57
10567233-2	1999	We prepared recombinant human H-FABP proteins with mutations in the hydrophobic patch (Phe(4), Trp(8) and Phe(64)), portal region (Phe(16)), hinge region (Leu(66), Gly(67)), second portal region (Glu(72)) and at the protein surface (Lys(21)) respectively.	Glycine	164-167	fatty acid binding protein 3	Homo sapiens	30-36
11055120-7	2000	Two A--&gt;G transitions are detected, and it resulted in corresponding changes of amino acid (Asn--&gt;Asp and Glu--&gt;Gly) in the HSL protein, respectively.	Glycine	121-124	lipase E, hormone sensitive type	Sus scrofa	133-136
10567237-1	1999	The high-affinity interaction of integrin alpha5beta1 with the central cell-binding domain of fibronectin requires both the Arg-Gly-Asp (RGD) sequence (in the tenth type III repeat) and a second site Pro-His-Ser-Arg-Asn (PHSRN) in the adjacent ninth type III repeat, which synergizes with RGD.	Glycine	128-131	fibronectin 1	Homo sapiens	94-105
10562577-2	1999	AIMS: To investigate the therapeutic effect of antibodies, raised against the Gastrimmune immunogen, which neutralise the glycine extended and carboxy amidated forms of gastrin 17 in two human gastric cancer models.	Glycine	122-129	gastrin	Mus musculus	169-176
10561591-1	1999	To elucidate the decisive structural factors relevant for dipeptide-carrier interaction, the affinity of short amide and imide derivatives for the intestinal H+/peptide symporter (PEPT1) was investigated by measuring their ability to inhibit Gly-Sar transport in Caco-2 cells.	Glycine	242-245	solute carrier family 15 member 1	Homo sapiens	180-185
10628124-8	1999	Finally, androgen receptor gene polymorphisms leading to shorter or longer glutamine and glycine residues in the receptor protein are correlated with racial variation in the incidence and severity of prostate cancer.	Glycine	89-96	androgen receptor	Homo sapiens	9-26
10641795-5	1999	We observed time-dependent losses of apoB histidine, lysine and glycine.	Glycine	64-71	apolipoprotein B	Homo sapiens	37-41
10597218-6	1999	The generation of p52 is dependent on a glycine-rich region (GRR) located upstream of the p52 C-terminus, and repositioning of this GRR alters the location of proteasome processing.	Glycine	40-47	nuclear factor kappa B subunit 2	Homo sapiens	18-21
10581413-0	1999	A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alters agonist efficacy.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	78-81
10581413-1	1999	Alanine 714 of the NMDA receptor NR1 subunit resides in the glycine binding pocket.	Glycine	60-67	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	33-36
10564180-0	1999	Production of superoxide and TNF-alpha from alveolar macrophages is blunted by glycine.	Glycine	79-86	tumor necrosis factor	Homo sapiens	29-38
10564180-1	1999	Glycine blunts lipopolysaccharide (LPS)-induced increases in intracellular calcium concentration ([Ca(2+)](i)) and tumor necrosis factor-alpha (TNF-alpha) production by Kupffer cells through a glycine-gated chloride channel.	Glycine	0-7	tumor necrosis factor	Homo sapiens	115-142
10564180-1	1999	Glycine blunts lipopolysaccharide (LPS)-induced increases in intracellular calcium concentration ([Ca(2+)](i)) and tumor necrosis factor-alpha (TNF-alpha) production by Kupffer cells through a glycine-gated chloride channel.	Glycine	0-7	tumor necrosis factor	Homo sapiens	144-153
10564180-4	1999	The ability of glycine to prevent endotoxin [lipopolysaccharide (LPS)]-induced increases in [Ca(2+)](i) and subsequent production of superoxide and TNF-alpha in alveolar macrophages was examined.	Glycine	15-22	tumor necrosis factor	Homo sapiens	148-157
10564180-10	1999	Moreover, TNF-alpha production was also inhibited by glycine and also required nearly 10 microM glycine for half-inhibition.	Glycine	53-60	tumor necrosis factor	Homo sapiens	10-19
10564180-10	1999	Moreover, TNF-alpha production was also inhibited by glycine and also required nearly 10 microM glycine for half-inhibition.	Glycine	96-103	tumor necrosis factor	Homo sapiens	10-19
10567023-5	1999	Human (h)[Gly(2)]GLP-2 significantly improved survival whether administered before, concomitant with, or after indomethacin.	Glycine	10-13	glucagon	Homo sapiens	17-22
10567023-6	1999	h[Gly(2)]GLP-2-treated mice exhibited reduced histological evidence of disease activity, fewer intestinal ulcerations, and decreased myeloperoxidase activity in the small bowel (P &lt; 0.05, h[Gly(2)]GLP-2- vs. saline-treated controls).	Glycine	2-5	glucagon	Homo sapiens	9-14
10567023-6	1999	h[Gly(2)]GLP-2-treated mice exhibited reduced histological evidence of disease activity, fewer intestinal ulcerations, and decreased myeloperoxidase activity in the small bowel (P &lt; 0.05, h[Gly(2)]GLP-2- vs. saline-treated controls).	Glycine	193-196	glucagon	Homo sapiens	9-14
10627046-0	1999	The PE-PGRS glycine-rich proteins of Mycobacterium tuberculosis: a new family of fibronectin-binding proteins?	Glycine	12-19	fibronectin 1	Homo sapiens	81-92
10559137-3	1999	The amino acid sequences in interstitial collagen (Gly-Leu/Ile) and laminin-5 (Ala-Leu) that are cleaved by MMP-2 are homologous to a region (Gly(32)-Leu(33)) within human big endothelin-1[1 to 38] (big ET-1).	Glycine	51-54	endothelin 1	Homo sapiens	176-188
10559137-3	1999	The amino acid sequences in interstitial collagen (Gly-Leu/Ile) and laminin-5 (Ala-Leu) that are cleaved by MMP-2 are homologous to a region (Gly(32)-Leu(33)) within human big endothelin-1[1 to 38] (big ET-1).	Glycine	51-54	endothelin 1	Homo sapiens	203-207
10559137-3	1999	The amino acid sequences in interstitial collagen (Gly-Leu/Ile) and laminin-5 (Ala-Leu) that are cleaved by MMP-2 are homologous to a region (Gly(32)-Leu(33)) within human big endothelin-1[1 to 38] (big ET-1).	Glycine	142-145	endothelin 1	Homo sapiens	176-188
10559137-3	1999	The amino acid sequences in interstitial collagen (Gly-Leu/Ile) and laminin-5 (Ala-Leu) that are cleaved by MMP-2 are homologous to a region (Gly(32)-Leu(33)) within human big endothelin-1[1 to 38] (big ET-1).	Glycine	142-145	endothelin 1	Homo sapiens	203-207
10559137-8	1999	Incubation of big ET-1 with recombinant human MMP-2 resulted in the specific cleavage of the Gly(32)-Leu(33) bond of big ET-1.	Glycine	93-96	endothelin 1	Homo sapiens	18-22
10559137-8	1999	Incubation of big ET-1 with recombinant human MMP-2 resulted in the specific cleavage of the Gly(32)-Leu(33) bond of big ET-1.	Glycine	93-96	endothelin 1	Homo sapiens	121-125
10597236-8	1999	The codon 90 Gly &gt; Asp alteration may represent a non-pathological polymorphism and consequently the mutation frequency reported in lung cancers may have been overstated and the designation of PPP2R1B as a tumor suppressor gene should be regarded with caution.	Glycine	13-16	protein phosphatase 2 scaffold subunit Abeta	Homo sapiens	196-203
10521252-12	1999	The [Gly(1),Arg(19)]hPTH-(1-28) analogue, in particular, should prove useful in dissociating AC- from PLC-dependent actions of PTH.	Glycine	5-8	parathyroid hormone	Homo sapiens	21-24
10516046-3	1999	Substitution of glycine (G) for tryptophan (W) at this position (W102G Env) in the nonpathogenic MLV FB29 induces both syncytium formation and neurologic disease in vivo.	Glycine	16-23	melanoma antigen	Mus musculus	71-74
10523664-0	1999	The glycine-phenylalanine-rich region determines the specificity of the yeast Hsp40 Sis1.	Glycine	4-11	type I HSP40 co-chaperone YDJ1	Saccharomyces cerevisiae S288C	78-83
10614581-0	1999	Most calretinin-containing amacrine cells in the rabbit retina co-localize glycine.	Glycine	75-82	calbindin 2	Homo sapiens	5-15
10614581-7	1999	Since calretinin-positive cells in the ganglion cell layer have been identified as ganglion cells based on soma size and presence of calretinin-positive axons in the optic nerve fiber layer, this population may represent a class of ganglion cell which contains glycine.	Glycine	261-268	calbindin 2	Homo sapiens	6-16
10514288-2	1999	The same modification was performed on the potent bradykinin B(2) receptor antagonist HOE 140 (H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH), in which the -D-Tic-Oic- moiety was replaced by D-BT to yield H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-BT-Arg-OH, 1 (JMV1116).	Glycine	115-118	kininogen 1	Homo sapiens	50-60
10514288-2	1999	The same modification was performed on the potent bradykinin B(2) receptor antagonist HOE 140 (H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH), in which the -D-Tic-Oic- moiety was replaced by D-BT to yield H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-BT-Arg-OH, 1 (JMV1116).	Glycine	114-118	kininogen 1	Homo sapiens	50-60
10497166-5	1999	These results demonstrate that the reactive center loop sequence determines the specificity of allosterically activated antithrombin for factor Xa and that the conformational flexibility of the P2 Gly may be critical for optimal bridging of antithrombin and thrombin by physiologic heparin and for preventing antithrombin from reacting as a substrate in the bridging complex.	Glycine	197-200	coagulation factor II, thrombin	Homo sapiens	124-132
10486054-6	1999	On the other hand, when Glu-248, Ala-262, Thr-274, Leu-285, Gly-313, Ala-322, or Val-335 of CvaA protein was mutated, the secretion of ColV was greatly reduced in certain mutants.	Glycine	60-63	CvaA	Escherichia coli	92-96
10491185-5	1999	Pure HemA was recovered in yields of 5-7 mg x L-1 of starting bacterial culture and pure HemT at 10 mg x L-1 x HemA has a final specific activity of 13 U x mg-1 with 1 unit defined as 1 micromol of 5-aminolaevulinic acid formed per hour at 37 degrees C. The Km values for HemA are 1.9 mM for glycine and 17 microM for succinyl-CoA, with the enzyme showing a turnover number of 430 h-1.	Glycine	292-299	glycosylphosphatidylinositol anchored molecule like	Mus musculus	89-93
10525358-4	1999	A peptide with neurokinin A-like immunoreactivity (Ser-Ser-Ala-Asn-Arg-Gln-Ile-Thr-Gly-Lys(10)Arg-Gln-Lys-Ile-Asn-Ser-P he-Val-Gly-Leu(20)Met.NH(2)) was isolated from sturgeon brain and contains 10 amino acid substitutions compared with human neuropeptide gamma (a specific product of the posttranslational processing of gamma-preprotachykinin A) but only 4 substitutions compared with trout neuropeptide gamma.	Glycine	83-86	tachykinin precursor 1	Homo sapiens	243-261
10525358-4	1999	A peptide with neurokinin A-like immunoreactivity (Ser-Ser-Ala-Asn-Arg-Gln-Ile-Thr-Gly-Lys(10)Arg-Gln-Lys-Ile-Asn-Ser-P he-Val-Gly-Leu(20)Met.NH(2)) was isolated from sturgeon brain and contains 10 amino acid substitutions compared with human neuropeptide gamma (a specific product of the posttranslational processing of gamma-preprotachykinin A) but only 4 substitutions compared with trout neuropeptide gamma.	Glycine	83-86	tachykinin precursor 1	Homo sapiens	392-410
10497221-7	1999	Polycystin-2 translation products truncated at or after Gly(821) retain their exclusive endoplasmic reticulum localization while products truncated at or before Glu(787) additionally traffic to the plasma membrane.	Glycine	56-59	polycystin 2, transient receptor potential cation channel	Homo sapiens	0-12
10518318-0	1999	Arginine methylation of a glycine and arginine rich peptide derived from sequences of human FMRP and fibrillarin.	Glycine	26-33	fragile X messenger ribonucleoprotein 1	Homo sapiens	92-96
10685364-6	1999	This HLA genotype expresses aspartic acid at position 57 and glycine at position 70 on the DQ beta chain, suggesting a capability to bind certain bacterial antigens.	Glycine	61-68	major histocompatibility complex, class II, DR beta 1	Homo sapiens	5-8
10481026-7	1999	In contrast, a mutation in the nuclear gene crs1 prevents splicing of only one intron but causes specific additional effects as precursor transcripts for tRNA-Ile(GAU), tRNA-Ala(UGC), tRNA-Lys(UUU)and tRNA-Val(UAC), but not tRNA-Gly(UCC), have significantly enhanced steady-state levels in this mutant.	Glycine	229-232	chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic	Zea mays	44-48
10467133-8	1999	PP1 can inhibit Ser/Thr kinases if the residue corresponding to Ile338 in v-Src is mutated to glycine.	Glycine	94-101	inorganic pyrophosphatase 1	Homo sapiens	0-3
10582243-9	1999	The C-terminal glycine residue of a novel modifier protein Apg12p, a 186-amino-acid protein, is conjugated to a lysine residue of Apg5p, a 294-amino-acid protein, via an isopeptide bond.	Glycine	15-22	Atg5p	Saccharomyces cerevisiae S288C	130-135
10628393-5	1999	In contrast to previous studies showing p53-dependent GML expression, of the 3 cell lines expressing GML mRNA, one had a p53 gene mutation (codon 245: Gly to Cys).	Glycine	151-154	tumor protein p53	Homo sapiens	121-124
10556575-0	1999	Corrigendum to: "Exposure of the cryptic arg-gly-Asp sequence in thrombospondin-1 by protein disulfide isomerase".	Glycine	45-48	thrombospondin 1	Homo sapiens	65-81
10467133-8	1999	PP1 can inhibit Ser/Thr kinases if the residue corresponding to Ile338 in v-Src is mutated to glycine.	Glycine	94-101	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	76-79
10460241-5	1999	Yet, all neurons responded to exogenous applications of both GABA and glycine, indicating that they expressed both GABA(A)Rs and GlyRs.	Glycine	70-77	glycyl-tRNA synthetase 1	Rattus norvegicus	115-134
10486177-0	1999	The IGF-I amino-terminal tripeptide glycine-proline-glutamate (GPE) is neuroprotective to striatum in the quinolinic acid lesion animal model of Huntington"s disease.	Glycine	36-43	insulin like growth factor 1	Homo sapiens	4-9
10486177-3	1999	Using this animal model of Huntington"s disease, we investigated the ability of the insulin-like growth factor-I (IGF-I) amino-terminal tripeptide glycine-proline-glutamate (GPE) to protect striatal neurons from degeneration.	Glycine	147-154	insulin like growth factor 1	Homo sapiens	84-112
10486177-3	1999	Using this animal model of Huntington"s disease, we investigated the ability of the insulin-like growth factor-I (IGF-I) amino-terminal tripeptide glycine-proline-glutamate (GPE) to protect striatal neurons from degeneration.	Glycine	147-154	insulin like growth factor 1	Homo sapiens	114-119
10511819-5	1999	The synthesized Gly-MIT and Gly-DIT were separated on a mu Bondapak C18 column employing stepwise gradient systems of a 0.1% trifluoroacetic acid/acetonitrile mixture and a water/acetonitrile mixture.	Glycine	16-19	Bardet-Biedl syndrome 9	Homo sapiens	68-71
10485845-4	1999	Protein-protein interaction assays suggest that Gro and Rpd3 form a complex in vivo and that they interact directly via the glycine/proline rich (GP) domain in Gro.	Glycine	124-131	groucho	Drosophila melanogaster	48-51
10485845-4	1999	Protein-protein interaction assays suggest that Gro and Rpd3 form a complex in vivo and that they interact directly via the glycine/proline rich (GP) domain in Gro.	Glycine	124-131	groucho	Drosophila melanogaster	160-163
10457370-15	1999	It is proposed that, in neural tissue, glycine is metabolized by the combined action of SHMT and the GCS.	Glycine	39-46	serine hydroxymethyltransferase 1	Rattus norvegicus	88-92
10446333-1	1999	Muller glial cells express two transport systems for glycine (Gly): one with low affinity and another identified as GLYT1 with high affinity.	Glycine	53-60	solute carrier family 6 member 9	Homo sapiens	116-121
10509806-3	1999	Amino acid sequencing, up to residue 45, showed a correct primary structure including the two additional amino acids at the N-terminus, Gly and Ser, derived from the thrombin cleavage site.	Glycine	136-139	coagulation factor II	Rattus norvegicus	166-174
10439317-3	1999	The DRB1 gene is polymorphic at residue 86, encoding valine or glycine.	Glycine	63-70	major histocompatibility complex, class II, DR beta 1	Homo sapiens	4-8
10377239-1	1999	The transferrin receptor contains a highly conserved Arg-Gly-Asp (RGD) sequence in the C-terminal region where transferrin is thought to bind.	Glycine	57-60	transferrin	Homo sapiens	4-15
10457201-5	1999	Adhesion of MTC-1 cells to E-cadherin-Fc was inhibited by arginine-glycine-aspartate (RGD) peptides and vice versa cells bound to immobilized RGD polymer in an M290-dependent fashion, where adhesion was inhibitable with soluble E-cadherin-Fc.	Glycine	67-74	cadherin 1	Mus musculus	27-37
10409145-4	1999	However, although gastrin-deficient mice show no changes in gastric proliferation, they do show reduced colonic proliferation, and rates of colonic proliferation are increased in transgenic mice overexpressing glycine-extended gastrin or progastrin.	Glycine	210-217	gastrin	Mus musculus	18-25
10409145-4	1999	However, although gastrin-deficient mice show no changes in gastric proliferation, they do show reduced colonic proliferation, and rates of colonic proliferation are increased in transgenic mice overexpressing glycine-extended gastrin or progastrin.	Glycine	210-217	gastrin	Mus musculus	227-234
10377239-1	1999	The transferrin receptor contains a highly conserved Arg-Gly-Asp (RGD) sequence in the C-terminal region where transferrin is thought to bind.	Glycine	57-60	transferrin	Homo sapiens	111-122
10358088-4	1999	Although this single substitution in YAP WW1 domain is sufficient to precipitate the two protein isoforms of Mena, an in vivo ligand of FE65, we showed that an additional substitution, histidine 192 (betaB7) to glycine, significantly increased the ability of YAP to mimic FE65.	Glycine	211-218	Yes1 associated transcriptional regulator	Rattus norvegicus	37-40
10436086-5	1999	NC10 scFv molecules containing linkers of three and four residues showed a strong preference for dimer formation (diabodies), whereas a linker length of one or two glycine residues prevented the formation of diabodies and directed scFv association into trimers (triabodies).	Glycine	164-171	immunglobulin heavy chain variable region	Homo sapiens	231-235
10468052-12	1999	Increases in intracellular calcium and production of TNF-alpha by isolated Kupffer cells stimulated by endotoxin were elevated significantly by hemorrhagic shock, alterations which were totally prevented by glycine.	Glycine	207-214	tumor necrosis factor	Rattus norvegicus	53-62
10468052-13	1999	Taken together, it is concluded that glycine reduces organ injury and mortality caused by hemorrhagic shock by preventing free radical production and TNF-alpha formation.	Glycine	37-44	tumor necrosis factor	Rattus norvegicus	150-159
10362520-4	1999	2-D gel electrophoresis of RNase-treated yeast extracts allowed us to tentatively identify the glycine- and arginine-rich (GAR) domain-containing proteins Gar1, Nop1, Sbp1, and Npl3 as major methyl-acceptors based on their known isoelectric points and apparent molecular weights.	Glycine	95-102	H/ACA snoRNP pseudouridylase subunit GAR1	Saccharomyces cerevisiae S288C	155-159
10347151-3	1999	Because serine hydroxymethyltransferase is responsible for the interconversion between serine and glycine, SDH, SPT/AGT, and GCS were considered to be the metabolic exits of the serine-glycine pool.	Glycine	185-192	serine racemase	Rattus norvegicus	107-110
10362520-4	1999	2-D gel electrophoresis of RNase-treated yeast extracts allowed us to tentatively identify the glycine- and arginine-rich (GAR) domain-containing proteins Gar1, Nop1, Sbp1, and Npl3 as major methyl-acceptors based on their known isoelectric points and apparent molecular weights.	Glycine	95-102	rRNA methyltransferase NOP1	Saccharomyces cerevisiae S288C	161-165
10488415-5	1999	There were 6 conserved amino acids in HVR1: AA385(Thr), AA389, 390, 406(Gly), AA401(Ser) and AA403(Phe).	Glycine	72-75	vasoactive intestinal peptide receptor 1	Homo sapiens	38-42
10408337-4	1999	In the present study, it was found that a beta-helix formed from A beta34-42 accounts for features suggested by published rotational resonance solid-state NMR data, including an anomalous conformation about the Gly-37-Gly-38 region and exaggerated pleating.	Glycine	211-214	amyloid beta precursor protein	Homo sapiens	40-46
10408337-4	1999	In the present study, it was found that a beta-helix formed from A beta34-42 accounts for features suggested by published rotational resonance solid-state NMR data, including an anomalous conformation about the Gly-37-Gly-38 region and exaggerated pleating.	Glycine	218-221	amyloid beta precursor protein	Homo sapiens	40-46
10347152-7	1999	Because an important role in the conversion of glyoxylate to glycine has been assigned to peroxisomal SPT/AGT from the studies on primary hyperoxaluria type 1, these results suggest that SPT/AGT in this organelle plays dual roles in the metabolism of glyoxylate and serine.	Glycine	61-68	angiotensinogen	Oryctolagus cuniculus	106-109
10347152-7	1999	Because an important role in the conversion of glyoxylate to glycine has been assigned to peroxisomal SPT/AGT from the studies on primary hyperoxaluria type 1, these results suggest that SPT/AGT in this organelle plays dual roles in the metabolism of glyoxylate and serine.	Glycine	61-68	angiotensinogen	Oryctolagus cuniculus	191-194
10366190-4	1999	The GLYT1 mRNA was transiently upregulated by the second day after ischemia in astrocytelike cells in close vicinity to hippocampal CA1 pyramidal neurons, possibly to reduce glycine concentration in the local extracellular spaces.	Glycine	174-181	solute carrier family 6 member 9	Homo sapiens	4-9
10207090-0	1999	Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain.	Glycine	106-113	nuclear factor kappa B subunit 1	Homo sapiens	67-76
10328917-7	1999	However, glycine extraction resulted in a 40 to 50% decrease in the elastic modulus along with a dramatic reduction in the hyalin protein at the apical ECM, thus implicating the apical ECM as a major mechanical component of the blastula wall.	Glycine	9-16	LOW QUALITY PROTEIN: hyalin	Strongylocentrotus purpuratus	123-129
10226945-4	1999	The other tumor (case 33) had a point mutation at codon 266, changing GGA to AGA and causing a substitution of glycine to arginine in the p53 protein.	Glycine	111-118	tumor protein p53	Homo sapiens	138-141
10207090-0	1999	Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain.	Glycine	106-113	nuclear factor kappa B subunit 1	Homo sapiens	87-91
10207090-5	1999	It has been shown that a Gly-rich region (GRR) at the C-terminal domain of p50 is an important processing signal.	Glycine	25-28	nuclear factor kappa B subunit 1	Homo sapiens	75-78
10207090-7	1999	Structural analysis reveals that a short sequence containing a few Gly residues and a single essential Ala is sufficient to generate p50.	Glycine	67-70	nuclear factor kappa B subunit 1	Homo sapiens	133-136
10187845-6	1999	The GCV1 region conferred a glycine response on an heterologous promoter acting as a repressor or activator depending on promoter context.	Glycine	28-35	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	4-8
10187845-7	1999	A protein was identified that bound to the glycine regulatory regions of GCV1 and GCV2 only if the CTTCTT motif was intact.	Glycine	43-50	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	73-77
10207163-0	1999	Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation.	Glycine	18-25	gastrin	Mus musculus	35-42
10206579-8	1999	In phenotype I, 9 of 12 patients had a sequence change in exon 42 of the ABCR gene in which the amino acid glutamic acid was substituted for glycine (Gly1961Glu).	Glycine	141-148	ATP binding cassette subfamily A member 4	Homo sapiens	73-77
10321477-2	1999	Transgenic mice over-expressing the human SOD1 gene containing a Gly--&gt;Ala substitution at position 93 (G93A) were employed to explore the effects of the SOD1 mutation on choline acetyltransferase (ChAT) expression in the striatum, and in the lumbar and cervical spinal cord.	Glycine	65-68	superoxide dismutase 1	Homo sapiens	42-46
10650340-10	1999	It is concluded that glycine transport by channel catfish brain has much in common with transport by mammalian nervous tissue which is carried out by the membrane carriers GLYT1 and GLYT2.	Glycine	21-28	solute carrier family 6 member 9	Homo sapiens	172-177
10072425-4	1999	The SYT protein has a novel conserved 54 amino acid domain at the N-terminus of the protein (the SNH domain) which is found in proteins from a wide variety of species, and a C-terminal domain, rich in glutamine, proline, glycine and tyrosine (the QPGY domain), which contains the transcriptional activator sequences.	Glycine	221-228	SS18 subunit of BAF chromatin remodeling complex	Homo sapiens	4-7
10213871-2	1999	Since the pivotal demonstration in 1984 by Pierschbacher and Ruoslahti that cell adhesion mediated by fibronectin could be inhibited by the simple tripeptide, Arg-Gly-Asp (RGD), then number of other peptide sequences have been shown to recapitulate integrin-ligand interactions.	Glycine	163-166	fibronectin 1	Homo sapiens	102-113
10098879-1	1999	In this study, we have further delineated the domains of the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine co-agonist binding site.	Glycine	126-133	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	91-94
10098879-2	1999	Taking an iterative approach, we have constructed truncation mutants of the NR1 subunit, transiently expressed them in HEK-293 cells, and determined the binding of the glycine site antagonist [3H]L-689,560.	Glycine	168-175	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	76-79
10363648-12	1999	We concluded that the first ubiquitin moiety is attached via its C-terminal Gly to the N-terminal residue of MyoD, and the polyubiquitin chain is then synthesized on Lys48 of this moiety.	Glycine	76-79	myogenic differentiation 1	Homo sapiens	109-113
10066772-19	1999	These studies indicate that HK binds to a region of 20 amino acids coded by exon 1 on CK1 which is carboxyl-terminal to its glycine-rich amino-terminal globular domain.	Glycine	124-131	kininogen 1	Homo sapiens	28-30
10214948-3	1999	A VPE with a substitution of the active site Cys with Gly showed no ability to convert itself into the mature form, although a wild VPE had the ability.	Glycine	54-57	vacuolar-processing enzyme	Ricinus communis	2-5
10077621-8	1999	The mutator effects of the deletion mutant and the Gly --&gt; Ala missense mutant in yeast MSH2 are enhanced by heterozygosity for a missense mutation in DNA polymerase delta that reduces its proofreading activity but is not a mutator in the heterozygous state.	Glycine	51-54	mismatch repair ATPase MSH2	Saccharomyces cerevisiae S288C	91-95
10072754-1	1999	The human DNA- and RNA-binding protein JKTBP is a member of a 2xRNA-binding domain (RBD)-glycine family of heterogeneous nuclear ribonucleoproteins that are involved in mRNA biogenesis.	Glycine	89-96	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	39-44
10064624-0	1999	Immunomodulatory effects of glycine on LPS-treated monocytes: reduced TNF-alpha production and accelerated IL-10 expression.	Glycine	28-35	tumor necrosis factor	Rattus norvegicus	70-79
10064624-3	1999	The amino acid glycine (GLY) has been shown to protect against endotoxin shock in the rat by inhibiting TNF-alpha production.	Glycine	24-27	tumor necrosis factor	Rattus norvegicus	104-113
10064624-6	1999	GLY decreased LPS-induced TNF-alpha production (P&lt;0.01) and increased IL-10 expression of purified monocytes.	Glycine	0-3	tumor necrosis factor	Rattus norvegicus	26-35
10085335-5	1999	Moreover, spinal inhibition of nociceptive activity of deep WDR STT neurons elicited by iontophoretic release of glycine and GABA agonists was attenuated by administration of SIN-1.	Glycine	113-120	MAPK associated protein 1	Homo sapiens	175-180
15992080-2	1999	A combination of a di-arginine addition to the C-terminal of the insulin B-chain, and a glycine substitution in the A-chain, produce an insulin which is soluble at acid pH, but precipitates in sc.	Glycine	88-95	insulin	Homo sapiens	136-143
10084598-3	1999	G319S is within the proline II-rich domain of the trans-activation site of HNF-1alpha and alters a glycine residue that is conserved throughout evolution.	Glycine	99-106	HNF1 homeobox A	Homo sapiens	75-85
10064733-6	1999	Abeta in which amino acids 13 through 17 (HHQKL) were replaced by glycine (GGQGL) failed to compete with the cellular uptake of apoE enriched betaVLDL.	Glycine	66-73	amyloid beta precursor protein	Homo sapiens	0-5
10069801-1	1999	We reported previously that a conformation-specific antibody, Ab P2, to a 16-amino acid peptide (Glu-Gly-Tyr-Lys-Lys-Lys-Tyr-Gln-Gln-Val-Asp-Glu-Glu-Phe-Leu-Arg) of the cytoplasmic domain of the beta-type platelet-derived growth factor receptor also recognizes the epidermal growth factor (EGF) receptor.	Glycine	101-104	platelet derived growth factor receptor beta	Homo sapiens	195-244
10069801-1	1999	We reported previously that a conformation-specific antibody, Ab P2, to a 16-amino acid peptide (Glu-Gly-Tyr-Lys-Lys-Lys-Tyr-Gln-Gln-Val-Asp-Glu-Glu-Phe-Leu-Arg) of the cytoplasmic domain of the beta-type platelet-derived growth factor receptor also recognizes the epidermal growth factor (EGF) receptor.	Glycine	101-104	epidermal growth factor receptor	Homo sapiens	265-303
10404512-7	1999	Glycine-extended gastrin induced a dose-dependent increase in [3H]thymidine uptake in LoVo (143 +/- 8% versus control at 10(-10) M) and HT 29 (151 +/- 11% versus control at 10(-10) M) cells that was not inhibited by PD 134308 or by a mitogen-activated protein (MAP) or ERK kinase (MEK) inhibitor (PD 98509).	Glycine	0-7	mitogen-activated protein kinase kinase 7	Homo sapiens	281-284
10404512-10	1999	CONCLUSIONS: Glycine-extended gastrin receptors are present on human colon cancer cells that mediate glycine-extended gastrin"s trophic effects via a MEK-independent mechanism.	Glycine	13-20	mitogen-activated protein kinase kinase 7	Homo sapiens	150-153
10404512-10	1999	CONCLUSIONS: Glycine-extended gastrin receptors are present on human colon cancer cells that mediate glycine-extended gastrin"s trophic effects via a MEK-independent mechanism.	Glycine	101-108	mitogen-activated protein kinase kinase 7	Homo sapiens	150-153
10026140-2	1999	CyPA binds to the previously identified Gly-Pro90 site of the capsid protein p24, but its role remained unclear.	Glycine	40-43	transmembrane p24 trafficking protein 2	Homo sapiens	77-80
10213369-7	1999	RESULTS: The utility of the CHO-PEPT1 cell model was demonstrated by determining the uptake kinetics of Gly-Sar, a prototypical dipeptide transporter substrate.	Glycine	104-107	solute carrier family 15 member 1	Homo sapiens	32-37
10203026-3	1999	DRB1*0106 is identical to DRB1*0101 except for two codons, 71 (AGG--&gt;GCG) and 86 (GGT--&gt;GTG), changing the encoded arginine to alanine and glycine to valine.	Glycine	145-152	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-4
10203026-3	1999	DRB1*0106 is identical to DRB1*0101 except for two codons, 71 (AGG--&gt;GCG) and 86 (GGT--&gt;GTG), changing the encoded arginine to alanine and glycine to valine.	Glycine	145-152	major histocompatibility complex, class II, DR beta 1	Homo sapiens	26-30
10203026-3	1999	DRB1*0106 is identical to DRB1*0101 except for two codons, 71 (AGG--&gt;GCG) and 86 (GGT--&gt;GTG), changing the encoded arginine to alanine and glycine to valine.	Glycine	145-152	glucagon	Homo sapiens	72-75
10064624-7	1999	Similarly, in a whole blood assay, GLY reduced TNF-alpha (P&lt;0.0001) and IL-1beta (P&lt;0.0001) synthesis and increased IL-10 expression (P&lt;0.05) in a dose-dependent manner.	Glycine	35-38	tumor necrosis factor	Rattus norvegicus	47-56
10064624-7	1999	Similarly, in a whole blood assay, GLY reduced TNF-alpha (P&lt;0.0001) and IL-1beta (P&lt;0.0001) synthesis and increased IL-10 expression (P&lt;0.05) in a dose-dependent manner.	Glycine	35-38	interleukin 1 beta	Rattus norvegicus	75-83
10064624-9	1999	Furthermore, GLY decreased the amount of IL-1beta and TNF-alpha-specific mRNA.	Glycine	13-16	interleukin 1 beta	Rattus norvegicus	41-49
10064624-9	1999	Furthermore, GLY decreased the amount of IL-1beta and TNF-alpha-specific mRNA.	Glycine	13-16	tumor necrosis factor	Rattus norvegicus	54-63
10026140-4	1999	Both are located in the C-terminal domain of p24 around Gly-Pro157 and Gly-Pro224.	Glycine	56-59	transmembrane p24 trafficking protein 2	Homo sapiens	45-48
10026140-4	1999	Both are located in the C-terminal domain of p24 around Gly-Pro157 and Gly-Pro224.	Glycine	71-74	transmembrane p24 trafficking protein 2	Homo sapiens	45-48
10026140-6	1999	Between CyPA and an immature (unprocessed) form of p24, a Kd of approximately 8 microM was measured, which corresponded with the Kd of the best of the Gly-Pro90 peptides, indicating an association via this site.	Glycine	151-154	transmembrane p24 trafficking protein 2	Homo sapiens	51-54
10226806-2	1999	Human and rat IGFBP-6 lack 2 and 4 N-terminal cysteines and therefore the Gly-Cys-Gly-Cys-Cys motif present in IGFBPs 1-5.	Glycine	74-77	insulin-like growth factor binding protein 6	Rattus norvegicus	14-21
10208572-3	1999	Since [3H]L-689,560, [3H]CGP 39653 and [3H]ifenprodil label the glycine, glutamate and ifenprodil sites of the NMDA receptor complex, which are associated with NR1, NR1/NR2A and NR1/NR2B subunits respectively, our findings suggest that NR2B-containing receptors are selectively up-regulated in superior temporal cortex in schizophrenia.	Glycine	64-71	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	160-163
10208572-3	1999	Since [3H]L-689,560, [3H]CGP 39653 and [3H]ifenprodil label the glycine, glutamate and ifenprodil sites of the NMDA receptor complex, which are associated with NR1, NR1/NR2A and NR1/NR2B subunits respectively, our findings suggest that NR2B-containing receptors are selectively up-regulated in superior temporal cortex in schizophrenia.	Glycine	64-71	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	165-168
10208572-3	1999	Since [3H]L-689,560, [3H]CGP 39653 and [3H]ifenprodil label the glycine, glutamate and ifenprodil sites of the NMDA receptor complex, which are associated with NR1, NR1/NR2A and NR1/NR2B subunits respectively, our findings suggest that NR2B-containing receptors are selectively up-regulated in superior temporal cortex in schizophrenia.	Glycine	64-71	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	169-173
10208572-3	1999	Since [3H]L-689,560, [3H]CGP 39653 and [3H]ifenprodil label the glycine, glutamate and ifenprodil sites of the NMDA receptor complex, which are associated with NR1, NR1/NR2A and NR1/NR2B subunits respectively, our findings suggest that NR2B-containing receptors are selectively up-regulated in superior temporal cortex in schizophrenia.	Glycine	64-71	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	165-168
9918902-1	1999	An ELISA was developed for the measurement of N-telopeptides of the alpha2(I) collagen chain containing an isomerized Asp-Gly bond (beta-peptide) using polyclonal antibodies raised against the synthetic peptide.	Glycine	122-125	collagen type I alpha 2 chain	Homo sapiens	68-86
10196713-6	1999	This mutation abolishes the first of the vicinal cysteines (1619Cys-Gly-Leu- 1622Cys) present in the D4 von Willebrand factor (vWf) type D repeat.	Glycine	68-71	von Willebrand factor	Homo sapiens	127-130
10226806-2	1999	Human and rat IGFBP-6 lack 2 and 4 N-terminal cysteines and therefore the Gly-Cys-Gly-Cys-Cys motif present in IGFBPs 1-5.	Glycine	82-85	insulin-like growth factor binding protein 6	Rattus norvegicus	14-21
9882751-7	1999	Uptake of proline, glycine and glutamine via system ASC was identified by inhibition with alanine or serine.	Glycine	19-26	apoptosis-associated speck-like protein containing a CARD	Bos taurus	52-55
9924200-1	1999	In the biosynthesis of adrenomedullin (AM), an intermediate form, AM(1-52)-glycine-COOH (iAM), is cleaved from proAM and subsequently processed to a biologically active mature form, AM(1-52)-NH2 (mAM), by enzymatic amidation.	Glycine	75-82	activating transcription factor 7 interacting protein	Mus musculus	39-41
9924200-1	1999	In the biosynthesis of adrenomedullin (AM), an intermediate form, AM(1-52)-glycine-COOH (iAM), is cleaved from proAM and subsequently processed to a biologically active mature form, AM(1-52)-NH2 (mAM), by enzymatic amidation.	Glycine	75-82	activating transcription factor 7 interacting protein	Mus musculus	66-68
9924200-1	1999	In the biosynthesis of adrenomedullin (AM), an intermediate form, AM(1-52)-glycine-COOH (iAM), is cleaved from proAM and subsequently processed to a biologically active mature form, AM(1-52)-NH2 (mAM), by enzymatic amidation.	Glycine	75-82	activating transcription factor 7 interacting protein	Mus musculus	66-68
9924200-1	1999	In the biosynthesis of adrenomedullin (AM), an intermediate form, AM(1-52)-glycine-COOH (iAM), is cleaved from proAM and subsequently processed to a biologically active mature form, AM(1-52)-NH2 (mAM), by enzymatic amidation.	Glycine	75-82	activating transcription factor 7 interacting protein	Mus musculus	196-199
10333293-6	1999	PLTP Cys129 --&gt; Gly and PLTP Cys168 --&gt; Gly were secretion incompetent.	Glycine	19-22	phospholipid transfer protein	Homo sapiens	0-4
10333293-8	1999	Relative to wild-type PLTP, PLTP Cys5 --&gt; Gly and PLTP Cys318 --&gt; Gly exhibited similar specific activities but partially impaired PLTP synthesis and secretion.	Glycine	45-48	phospholipid transfer protein	Homo sapiens	28-32
9882303-6	1999	Using a series of fine mutants in which single amino acids between codons 379 and 386 were changed to glycine, we have found that mutations of Pro379, Glu381, Ser383, or Tyr384 diminish the ability of LMP1 CTAR2 to engage JNK signalling.	Glycine	102-109	mitogen-activated protein kinase 8	Homo sapiens	222-225
10333293-8	1999	Relative to wild-type PLTP, PLTP Cys5 --&gt; Gly and PLTP Cys318 --&gt; Gly exhibited similar specific activities but partially impaired PLTP synthesis and secretion.	Glycine	45-48	phospholipid transfer protein	Homo sapiens	28-32
10333293-8	1999	Relative to wild-type PLTP, PLTP Cys5 --&gt; Gly and PLTP Cys318 --&gt; Gly exhibited similar specific activities but partially impaired PLTP synthesis and secretion.	Glycine	45-48	phospholipid transfer protein	Homo sapiens	28-32
10333293-10	1999	The specific activities of PLTP Cys5 --&gt; Gly and PLTP Cys318 --&gt; Gly were similar in the cell lysates and medium, suggesting that glycosylation does not affect transfer activity.	Glycine	44-47	phospholipid transfer protein	Homo sapiens	27-31
10333293-10	1999	The specific activities of PLTP Cys5 --&gt; Gly and PLTP Cys318 --&gt; Gly were similar in the cell lysates and medium, suggesting that glycosylation does not affect transfer activity.	Glycine	71-74	phospholipid transfer protein	Homo sapiens	52-56
9893960-4	1999	Kinetic analysis and effects of addition either of uncoupler (protonophore) or by Gly-Sar, one of the good substrates of PEPT1, revealed that fluorescent dipeptides were taken up by passive diffusion.	Glycine	82-85	solute carrier family 15 member 1	Homo sapiens	121-126
9987163-4	1999	Here DNA coding for the mature bovine interleukin-6 (IL-6) protein was fused through a synthetic glycine linker to the 3" end of DNA coding for the mature BHV-1 gD (tgD) external domain.	Glycine	97-104	interleukin 6	Bos taurus	38-51
9987163-4	1999	Here DNA coding for the mature bovine interleukin-6 (IL-6) protein was fused through a synthetic glycine linker to the 3" end of DNA coding for the mature BHV-1 gD (tgD) external domain.	Glycine	97-104	interleukin 6	Bos taurus	53-57
11741208-12	1999	Transport characteristics of Gly-Sar from the basolateral to the apical side in adenovirus-transduced Caco-2 cells are in agreement with those from the apical to the basolateral side, indicating that hPepT1 is also expressed in the basolateral membrane and displays a similar level of transport enhancement after adenovirus mediated hPepT1 gene expression.	Glycine	29-32	solute carrier family 15 member 1	Homo sapiens	200-206
10226519-1	1999	We have deleted the interchain disulfide bonds in a chimeric anti-CEA antibody (chT84.66) by mutating two cysteines in the heavy chain to glycine residues.	Glycine	138-145	carcinoembryonic antigen gene family	Mus musculus	66-69
9878818-7	1999	The alpha-MSH is flanked at the C-terminus by Gly-Lys-Lys, representing an amidation signal.	Glycine	46-49	proopiomelanocortin	Homo sapiens	10-13
9880793-5	1999	US-1 had a typical Arg-Gly-Asp (RGD) sequence, which is responsible for blocking the binding of fibrinogen to the receptor.	Glycine	23-26	fibrinogen beta chain	Homo sapiens	96-106
9876130-2	1999	The dynamics of met-enkephalin is considerably more complicated than that of the previously studied glycine oligomers; met-enkephalin contains the interesting motions of phenyl groups and of side chains relative to the backbone, motions that are present in general flexible peptides.	Glycine	100-107	proopiomelanocortin	Homo sapiens	119-133
10319582-7	1999	The SNU-G2 proband harbored a missense mutation from aspartic acid (GAT) to glycine (GGT) at codon 244 in exon 6 of the E-cadherin gene, and the SNU-G1001 proband had a missense mutation from valine (GTG) to alanine (GCG) at codon 487 in exon 10.	Glycine	76-83	cadherin 1	Homo sapiens	120-130
10080694-5	1999	Sequence analysis revealed that AIR1 encodes a protein that is related to a large family of proteins that consist of a proline-rich or glycine-rich N-terminus and a hydrophobic, possibly membrane spanning C-terminus.	Glycine	135-142	Auxin-Induced in Root cultures 1	Arabidopsis thaliana	32-36
10403510-1	1999	In the biosynthesis of adrenomedullin (AM), glycine-extended AM, an intermediate form (iAM) processed from proAM is converted to AM[1-52]-NH2, the bioactive mature form of AM (mAM), by enzymatic amidation.	Glycine	44-51	activating transcription factor 7 interacting protein	Mus musculus	39-41
10403510-1	1999	In the biosynthesis of adrenomedullin (AM), glycine-extended AM, an intermediate form (iAM) processed from proAM is converted to AM[1-52]-NH2, the bioactive mature form of AM (mAM), by enzymatic amidation.	Glycine	44-51	activating transcription factor 7 interacting protein	Mus musculus	61-63
10403510-1	1999	In the biosynthesis of adrenomedullin (AM), glycine-extended AM, an intermediate form (iAM) processed from proAM is converted to AM[1-52]-NH2, the bioactive mature form of AM (mAM), by enzymatic amidation.	Glycine	44-51	activating transcription factor 7 interacting protein	Mus musculus	61-63
10403510-1	1999	In the biosynthesis of adrenomedullin (AM), glycine-extended AM, an intermediate form (iAM) processed from proAM is converted to AM[1-52]-NH2, the bioactive mature form of AM (mAM), by enzymatic amidation.	Glycine	44-51	activating transcription factor 7 interacting protein	Mus musculus	61-63
10403510-1	1999	In the biosynthesis of adrenomedullin (AM), glycine-extended AM, an intermediate form (iAM) processed from proAM is converted to AM[1-52]-NH2, the bioactive mature form of AM (mAM), by enzymatic amidation.	Glycine	44-51	activating transcription factor 7 interacting protein	Mus musculus	176-179
10080694-7	1999	Surprisingly, AIR1 lacks the proline-rich or glycine-rich N-terminus which is thought to be important for interaction with the cell wall.	Glycine	45-52	Auxin-Induced in Root cultures 1	Arabidopsis thaliana	14-18
9852036-14	1998	Mutagenic analyses suggested that this conjugation was formed via an isopeptide bond between the C-terminal glycine of hApg12 and Lys-130 of hApg5.	Glycine	108-115	autophagy related 5	Homo sapiens	141-146
9861038-5	1998	Furthermore, GLYT1 antagonist enhanced NMDAR function during perfusion with medium containing 10 microM glycine, a concentration similar to that in the cerebrospinal fluid in vivo, thereby supporting the hypothesis that the GLYT1 maintains subsaturating concentration of glycine at synaptically activated NMDAR.	Glycine	104-111	solute carrier family 6 member 9	Homo sapiens	13-18
9861038-5	1998	Furthermore, GLYT1 antagonist enhanced NMDAR function during perfusion with medium containing 10 microM glycine, a concentration similar to that in the cerebrospinal fluid in vivo, thereby supporting the hypothesis that the GLYT1 maintains subsaturating concentration of glycine at synaptically activated NMDAR.	Glycine	104-111	solute carrier family 6 member 9	Homo sapiens	224-229
9861038-5	1998	Furthermore, GLYT1 antagonist enhanced NMDAR function during perfusion with medium containing 10 microM glycine, a concentration similar to that in the cerebrospinal fluid in vivo, thereby supporting the hypothesis that the GLYT1 maintains subsaturating concentration of glycine at synaptically activated NMDAR.	Glycine	271-278	solute carrier family 6 member 9	Homo sapiens	13-18
9861038-5	1998	Furthermore, GLYT1 antagonist enhanced NMDAR function during perfusion with medium containing 10 microM glycine, a concentration similar to that in the cerebrospinal fluid in vivo, thereby supporting the hypothesis that the GLYT1 maintains subsaturating concentration of glycine at synaptically activated NMDAR.	Glycine	271-278	solute carrier family 6 member 9	Homo sapiens	224-229
9852036-4	1998	The C-terminal glycine of a novel modifier protein, Apg12p, is conjugated to a lysine residue of Apg5p via an isopeptide bond.	Glycine	15-22	autophagy related 12	Homo sapiens	52-58
9852036-4	1998	The C-terminal glycine of a novel modifier protein, Apg12p, is conjugated to a lysine residue of Apg5p via an isopeptide bond.	Glycine	15-22	autophagy related 5	Homo sapiens	97-102
9872404-2	1998	The structure of a Gly/Ala-rich insert in IkappaB alpha was probed by nuclear magnetic resonance (NMR) spectroscopy, comparing IkappaB alpha samples with and without Gly/Ala-rich insert.	Glycine	166-169	NFKB inhibitor alpha	Homo sapiens	42-55
9852036-14	1998	Mutagenic analyses suggested that this conjugation was formed via an isopeptide bond between the C-terminal glycine of hApg12 and Lys-130 of hApg5.	Glycine	108-115	autophagy related 12	Homo sapiens	119-125
9852595-4	1998	First, the glycine transporter GLYT1 is expressed by the glycine-containing amacrine cells but not by the glycine-containing bipolar cells, suggesting that only the amacrine cells are functionally glycinergic.	Glycine	11-18	solute carrier family 6 member 9	Homo sapiens	31-36
9852595-4	1998	First, the glycine transporter GLYT1 is expressed by the glycine-containing amacrine cells but not by the glycine-containing bipolar cells, suggesting that only the amacrine cells are functionally glycinergic.	Glycine	57-64	solute carrier family 6 member 9	Homo sapiens	31-36
9872404-0	1998	Random coil conformation of a Gly/Ala-rich insert in IkappaB alpha excludes structural stabilization as the mechanism for protection against proteasomal degradation.	Glycine	30-33	NFKB inhibitor alpha	Homo sapiens	53-66
9872404-2	1998	The structure of a Gly/Ala-rich insert in IkappaB alpha was probed by nuclear magnetic resonance (NMR) spectroscopy, comparing IkappaB alpha samples with and without Gly/Ala-rich insert.	Glycine	19-22	NFKB inhibitor alpha	Homo sapiens	42-55
9872404-2	1998	The structure of a Gly/Ala-rich insert in IkappaB alpha was probed by nuclear magnetic resonance (NMR) spectroscopy, comparing IkappaB alpha samples with and without Gly/Ala-rich insert.	Glycine	19-22	NFKB inhibitor alpha	Homo sapiens	127-140
9856844-5	1998	We now report a TBDN patient who is compound heterozygous for a recessive and a dominant glycine substitution mutation in COL7A1.	Glycine	89-96	N-alpha-acetyltransferase 15, NatA auxiliary subunit	Homo sapiens	16-20
10435350-3	1998	Thus, 17 pairs of NBD-amino acid enantiomers and NBD-glycine were separated on CSP 2 except for six NBD-amino acids (D-Asn, D-Ser, D-Gln, L-Pro, L-Ser and Gly).	Glycine	53-60	regulator of calcineurin 2	Homo sapiens	79-84
9848884-4	1998	Mean+/-SEM plasma EC-SOD in female patients (113.6+/-13.2 ng/mL) was significantly higher than in male patients (86.6+/-5.1 ng/mL, P&lt;0.0001), and all 19 patients with levels &gt;400 ng/mL were heterozygous for the Arg213--&gt;Gly mutation at the EC-SOD gene; there was also a positive correlation with age (r=0.131, P=0.0016).	Glycine	229-232	superoxide dismutase 3	Homo sapiens	18-24
9813131-4	1998	In the context of 4E insulin, the employed mutants, i.e. ThrA8--&gt;His and ValA3--&gt;Gly, result in species with 143% and 0.1% biological activity, respectively, relative to human insulin.	Glycine	87-90	insulin	Homo sapiens	21-28
9848655-2	1998	HRB87F/hrp36 is one of two Drosophila proteins that is most similar to mammalian A1 hnRNP, and like A1, consists of two copies of the RNA-binding domain (RBD) motif followed by a glycine-rich domain (GRD).	Glycine	179-186	Heterogeneous nuclear ribonucleoprotein at 87F	Drosophila melanogaster	0-12
9813131-4	1998	In the context of 4E insulin, the employed mutants, i.e. ThrA8--&gt;His and ValA3--&gt;Gly, result in species with 143% and 0.1% biological activity, respectively, relative to human insulin.	Glycine	87-90	insulin	Homo sapiens	182-189
9826525-2	1998	The amino acid sequence deduced from the cDNA showed that ESP-1 comprises a signal peptide of 18 amino acids, a propeptide of 23 amino acids, an active form sequence of 273 amino acids starting from an Ile-Val-Gly-Gly-Glu motif, the catalytic triad of serine proteases that has been characterized as the essential amino acid residues for the proteolytic activity, and a hydrophobic amino acid stretch in the carboxyl terminus, suggesting this enzyme is a novel membrane-type serine protease.	Glycine	210-213	serine protease 21	Homo sapiens	58-63
9808586-7	1998	Additionally, preincubation of HUVEC with a synthetic peptide Arg-Gly-Asp (RGD) that prevents vWf-mediated adhesion of SS RBC reduced the surface expression of VCAM-1 and NF-kB activation.	Glycine	66-69	von Willebrand factor	Homo sapiens	94-97
9826525-2	1998	The amino acid sequence deduced from the cDNA showed that ESP-1 comprises a signal peptide of 18 amino acids, a propeptide of 23 amino acids, an active form sequence of 273 amino acids starting from an Ile-Val-Gly-Gly-Glu motif, the catalytic triad of serine proteases that has been characterized as the essential amino acid residues for the proteolytic activity, and a hydrophobic amino acid stretch in the carboxyl terminus, suggesting this enzyme is a novel membrane-type serine protease.	Glycine	214-217	serine protease 21	Homo sapiens	58-63
9808586-7	1998	Additionally, preincubation of HUVEC with a synthetic peptide Arg-Gly-Asp (RGD) that prevents vWf-mediated adhesion of SS RBC reduced the surface expression of VCAM-1 and NF-kB activation.	Glycine	66-69	vascular cell adhesion molecule 1	Homo sapiens	160-166
9799507-7	1998	Determination of the C-terminus of soluble ACE-JMEGF revealed that, surprisingly, cleavage occurred at a Gly-Phe bond between the fifth and sixth cysteines within the third disulfide loop of the EGF-like domain.	Glycine	105-108	angiotensin-converting enzyme	Cricetulus griseus	43-46
9842991-2	1998	We detected associations between PON2 variation in codon 148 (Ala --&gt; Gly) and variation in fasting plasma concentrations of total and low-density lipoprotein (LDL) cholesterol and apolipoprotein (apo) B.	Glycine	73-76	apolipoprotein B	Homo sapiens	184-206
9797278-3	1998	The GLY1 gene encoding the threonine aldolase of A. gossypii was isolated by heterologous complementation of the glycine-auxotrophic Saccharomyces cerevisiae strain YM13 with a genomic library from A. gossypii.	Glycine	113-120	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	4-8
9795213-6	1998	The RBP56/hTAFII68, FUS/TLS and EWS proteins comprise a sub-family of RNA binding proteins, which consist of an N-terminal Ser, Gly, Gln and Tyr-rich region, an RNA binding domain, a Cys2/Cys2 zinc finger motif and a C-terminal RGG-containing region.	Glycine	128-131	FUS RNA binding protein	Homo sapiens	20-27
9839943-1	1998	Sarcosine dehydrogenase (SarDH) is a mitochondrial flavoenzyme involved in the oxidative degradation of choline to glycine.	Glycine	115-122	sarcosine dehydrogenase	Rattus norvegicus	0-23
9839943-1	1998	Sarcosine dehydrogenase (SarDH) is a mitochondrial flavoenzyme involved in the oxidative degradation of choline to glycine.	Glycine	115-122	sarcosine dehydrogenase	Rattus norvegicus	25-30
9814482-3	1998	These two additional C18 conversions can be catalyzed by CYP11B1 if serine-288 and valine-320 are replaced by the corresponding CYP11B2 residues, glycine and alanine.	Glycine	146-153	Bardet-Biedl syndrome 9	Homo sapiens	21-24
9769393-6	1998	On the other hand, an A to G substitution at codon 170 in exon 5 of p53 gene resulting in glutamic acid (ACG) to glycine (GCG) was detected in the DNA of her tongue cancer.	Glycine	113-120	tumor protein p53	Homo sapiens	68-71
9790668-6	1998	The IgG affects the rate at which thrombin cleaves various peptide p-nitroanilide substrates with arginine in the P1 position, increasing the kcat for substrates with a P2 glycine residue but generally decreasing the kcat for substrates with a P2 proline.	Glycine	172-179	coagulation factor II, thrombin	Homo sapiens	34-42
9804190-6	1998	We report here site-directed mutagenesis experiments which have led to the identification of two other amino acid residues, glycine 38 and 111, whose substitution in the polypeptide chain of the first generation dimeric mutant of RNase A, is capable of conferring to the mutein the full cytotoxic activity characteristic of native seminal RNase.	Glycine	124-131	ribonuclease pancreatic	Bos taurus	230-237
9778369-1	1998	Myristoyl-CoA:protein N-myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the cotranslational transfer of myristate to the NH2-terminal glycine residue of a number of important proteins of diverse function.	Glycine	162-169	N-myristoyltransferase 1	Homo sapiens	22-44
9778369-1	1998	Myristoyl-CoA:protein N-myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the cotranslational transfer of myristate to the NH2-terminal glycine residue of a number of important proteins of diverse function.	Glycine	162-169	N-myristoyltransferase 1	Homo sapiens	46-49
9809800-1	1998	The incretin and enterogastrone hormone, GLP-1, occurs in an amidated (GLP-1 (7-36) amide; 75%) and a glycine-extended (GLP-1 (7-37); 25%) form.	Glycine	102-109	glucagon	Homo sapiens	41-46
9783710-7	1998	It substituted a glycine residue within the triple helical domain (G934R) of alpha2(V) collagen, typical of the dominant negative changes in other collagens, which cause various other inherited connective tissue disorders.	Glycine	17-24	collagen type V alpha 2 chain	Homo sapiens	77-86
9790946-2	1998	Microglial cells solely cultured in medium devoid of serine (Ser), glycine (Gly) hardly expressed inducible NO synthase (iNOS), while those cocultured with neurons and astrocytes expressed iNOS.	Glycine	67-74	nitric oxide synthase 2	Rattus norvegicus	98-119
9790946-2	1998	Microglial cells solely cultured in medium devoid of serine (Ser), glycine (Gly) hardly expressed inducible NO synthase (iNOS), while those cocultured with neurons and astrocytes expressed iNOS.	Glycine	67-74	nitric oxide synthase 2	Rattus norvegicus	121-125
9790946-2	1998	Microglial cells solely cultured in medium devoid of serine (Ser), glycine (Gly) hardly expressed inducible NO synthase (iNOS), while those cocultured with neurons and astrocytes expressed iNOS.	Glycine	76-79	nitric oxide synthase 2	Rattus norvegicus	121-125
9746777-2	1998	Three sites on fibrinogen have been hypothesized to be critical for these interactions: the Ala-Gly-Asp-Val (AGDV) sequence at the C-terminus of the gamma chain and two Arg-Gly-Asp (RGD) sequences in the Aalpha chain.	Glycine	96-99	fibrinogen beta chain	Homo sapiens	15-25
9768693-5	1998	These in-frame variants lead to the insertion of three or six amino acids (Ser-Ser-Gly; Ser-Ser-Gly-Ser-Ser-Gly) carboxy-terminal to gamma-MSH.	Glycine	83-86	proopiomelanocortin	Homo sapiens	133-142
9768693-5	1998	These in-frame variants lead to the insertion of three or six amino acids (Ser-Ser-Gly; Ser-Ser-Gly-Ser-Ser-Gly) carboxy-terminal to gamma-MSH.	Glycine	96-99	proopiomelanocortin	Homo sapiens	133-142
9768693-5	1998	These in-frame variants lead to the insertion of three or six amino acids (Ser-Ser-Gly; Ser-Ser-Gly-Ser-Ser-Gly) carboxy-terminal to gamma-MSH.	Glycine	96-99	proopiomelanocortin	Homo sapiens	133-142
9753474-8	1998	Further, we demonstrate in vivo that at concentrations consistent with its IC50 as a cytokine inhibitor, SB203580 can inhibit stimulus-induced phosphorylation of p38 at the Thr-Gly-Tyr activation motif.	Glycine	177-180	mitogen-activated protein kinase 14	Homo sapiens	162-165
9729615-13	1998	Neomycin demonstrated a glycine-dependent enhancement of currents mediated by the NR1a-NR2A combination of subunits but a paradoxical depression was observed in saturating concentrations of glycine.	Glycine	24-31	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	87-91
9787104-11	1998	More physiological methods are those utilizing OGTT data, allowing calculation of an Insulin Sensitivity Index for glycemia, or ISI(gly), through the formula: 2/((INSp x GLYp)+1), where INSp and GLYp are the measured insulin and glycemic areas expressed by taking mean normal value as 1.	Glycine	115-118	insulin	Homo sapiens	85-92
9787104-11	1998	More physiological methods are those utilizing OGTT data, allowing calculation of an Insulin Sensitivity Index for glycemia, or ISI(gly), through the formula: 2/((INSp x GLYp)+1), where INSp and GLYp are the measured insulin and glycemic areas expressed by taking mean normal value as 1.	Glycine	115-118	insulin	Homo sapiens	217-224
9787104-12	1998	The corresponding Insulin Resistance Index, or IRI(gly), can be obtained through the formula: 2/((1/(INSp x GLYp))+1).	Glycine	51-54	insulin	Homo sapiens	18-25
9820601-7	1998	DRB1*1301 and DR15 in the responder haplotypes have a Val at this position while the nonresponder haplotype has a Gly.	Glycine	114-117	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-4
9784381-3	1998	No homology with known gene was detected at the DNA level, while the predicted protein is characterized by a glycine-rich region followed by a domain of 35 residues that shows high homology with the CAT56 gene, another gene of MHC class I.	Glycine	109-116	proline rich 3	Homo sapiens	199-204
9677373-1	1998	The contribution of the oxyanion hole to the functional architecture and to the hydrolytic efficiency of human acetylcholinesterase (HuAChE) was investigated through single replacements of its elements, residues Gly-121, Gly-122 and the adjacent residue Gly-120, by alanine.	Glycine	212-215	acetylcholinesterase (Cartwright blood group)	Homo sapiens	111-131
9759731-6	1998	The carboxy-terminal glycine residue of Apg12, a 186-amino-acid protein, is conjugated to a lysine at residue 149 of Apg5, a 294-amino-acid protein.	Glycine	21-28	Atg5p	Saccharomyces cerevisiae S288C	117-121
9735340-4	1998	[3H]Gly-sar uptake in cells transiently transfected with Y167A-hPepT1 was abolished completely, even though the level of Y167A-hPepT1 expression by Western blot analysis and cell surface expression by immunofluorescence microscopy was similar to those of the wild type.	Glycine	4-7	solute carrier family 15 member 1	Homo sapiens	63-69
9699501-2	1998	BSP possesses an integrin-binding RGD (Arg-Gly-Asp) domain, which may promote interactions between HBC cells and bone extracellular matrix.	Glycine	43-46	integrin binding sialoprotein	Homo sapiens	0-3
9708987-6	1998	The structure of a cross-linked derivative of B28 Asp insulin, containing an Ala-Lys dipeptide linker between residues B30 Ala and A1 Gly, has also determined.	Glycine	134-137	MIS18 kinetochore protein A	Homo sapiens	46-49
9708987-6	1998	The structure of a cross-linked derivative of B28 Asp insulin, containing an Ala-Lys dipeptide linker between residues B30 Ala and A1 Gly, has also determined.	Glycine	134-137	insulin	Homo sapiens	54-61
9742554-7	1998	In lyophilizates containing a crystallized excipient such as glycine or mannitol, IL-6 suffered destabilization, which was less pronounced if an additional amorphous excipient was present.	Glycine	61-68	interleukin 6	Homo sapiens	82-86
9850564-4	1998	Using 15N-Gly biosynthetically-labelled calmodulin, we have studied the binding of different metal ions to calmodulin, including K+, Na+, Ca2+, Mg2+, Zn2+, Cd2+, Pb2+, Hg2+, Sr2+, La3+ and Lu3+, by 1H,15N HMQC NMR experiments.	Glycine	10-13	calmodulin 1	Homo sapiens	40-50
9694963-11	1998	This beneficial effect of glycine may be partly explained by the fact that glycine increased influx of chloride into Kupffer cells leading to diminished tumor necrosis factor-alpha production.	Glycine	26-33	tumor necrosis factor	Rattus norvegicus	153-180
9694963-11	1998	This beneficial effect of glycine may be partly explained by the fact that glycine increased influx of chloride into Kupffer cells leading to diminished tumor necrosis factor-alpha production.	Glycine	75-82	tumor necrosis factor	Rattus norvegicus	153-180
9701247-2	1998	We report here that insertion of a minimal glycine-alanine repeat motif in different positions of I kappaB alpha protects this NF-kappaB inhibitor from signal-induced degradation dependent on ubiquitin-proteasome, and decreases its basal turnover in vivo resulting in constitutive dominant-negative mutants.	Glycine	43-50	NFKB inhibitor alpha	Homo sapiens	98-112
9701247-4	1998	This explains how functionally competent I kappaB alpha is protected from proteasomal disruption and identifies the glycine-alanine repeat as a new regulator of proteolysis.	Glycine	116-123	NFKB inhibitor alpha	Homo sapiens	41-55
9677373-1	1998	The contribution of the oxyanion hole to the functional architecture and to the hydrolytic efficiency of human acetylcholinesterase (HuAChE) was investigated through single replacements of its elements, residues Gly-121, Gly-122 and the adjacent residue Gly-120, by alanine.	Glycine	221-224	acetylcholinesterase (Cartwright blood group)	Homo sapiens	111-131
9635779-3	1998	Because of this orientation, the interaction between GroEL and two substrate proteins, citrate synthase from Saccharomyces cerevisiae with a destabilizing Gly--&gt;Ala mutation and RTEM beta-lactamase from Escherichia coli with two Cys--&gt;Ala mutations, could be studied by force spectroscopy under different conditions.	Glycine	155-158	GroEL	Escherichia coli	53-58
9703961-5	1998	This CCK Gly immunoreactive peptide was similar in size to CCK 8, and after treatment with arylsulfatase and carboxypeptidase B, it co-eluted on HPLC with unsulfated CCK 8 Gly.	Glycine	9-12	cholecystokinin	Homo sapiens	5-8
9703961-5	1998	This CCK Gly immunoreactive peptide was similar in size to CCK 8, and after treatment with arylsulfatase and carboxypeptidase B, it co-eluted on HPLC with unsulfated CCK 8 Gly.	Glycine	172-175	cholecystokinin	Homo sapiens	5-8
9703961-7	1998	This is the first demonstration that PC1 acting alone is able to cleave pro CCK liberating the amino terminal pro peptide and a glycine and arginine extended CCK 8 which is the immediate precursor of CCK 8 amide.	Glycine	128-135	cholecystokinin	Homo sapiens	76-79
9688907-5	1998	Two contiguous peptides from D5 in the histidine-glycine-rich region, Gly442-Lys458 and Phe459-Lys478, each inhibit the binding of HK to PMN.	Glycine	49-56	kininogen 1	Homo sapiens	131-133
9737781-3	1998	Sequencing of the PNP gene, which is located on chromosome 14ql3, of the patient led to the identification of three point mutations in exon 2 at amino acid positions 20 (His, silent mutation), 24 (Arg-->termination codon) and 51 (Ser-->Gly).	Glycine	236-239	purine nucleoside phosphorylase	Homo sapiens	18-21
9703961-3	1998	PC1 also generated a peptide which after carboxypeptidase B treatment, was detected with an antiserum specific for CCK Gly.	Glycine	119-122	cholecystokinin	Homo sapiens	115-118
9658205-8	1998	EAAT2 contains a histidine residue at the position corresponding to histidine 146 of EAAT1, but at the position corresponding to histidine 156 of EAAT1, EAAT2 has a glycine residue.	Glycine	165-172	solute carrier family 1 member 2	Homo sapiens	0-5
9658205-8	1998	EAAT2 contains a histidine residue at the position corresponding to histidine 146 of EAAT1, but at the position corresponding to histidine 156 of EAAT1, EAAT2 has a glycine residue.	Glycine	165-172	solute carrier family 1 member 3	Homo sapiens	146-151
9658205-8	1998	EAAT2 contains a histidine residue at the position corresponding to histidine 146 of EAAT1, but at the position corresponding to histidine 156 of EAAT1, EAAT2 has a glycine residue.	Glycine	165-172	solute carrier family 1 member 2	Homo sapiens	153-158
9658205-9	1998	Mutation of this glycine residue in EAAT2 to histidine generates a Zn2+ sensitive transporter, further confirming the role of this residue in conferring differential Zn2+ sensitivity.	Glycine	17-24	solute carrier family 1 member 2	Homo sapiens	36-41
9624170-5	1998	Significantly, we demonstrate that substitution of the nonpolar glycine residue for either or both of the conserved negatively charged aspartic acid residues at positions 174 and 175 in the full-length recombinant Nef protein background completely abrogated binding of c-Raf1 in vitro.	Glycine	64-71	S100 calcium binding protein B	Homo sapiens	214-217
9585570-1	1998	Characterization by kinetic and equilibrium methods of the interactions of cystatin A Gly-4 mutants with papain, cathepsin B, and cathepsin L.	Glycine	86-89	cathepsin L	Homo sapiens	130-141
9655336-2	1998	GNMT is a tetrameric enzyme (monomer Mr = 32,423Da, 292 amino acids) that catalyzes the transfer of a methyl group from S-adenosylmethionine (AdoMet) to glycine with the formation of S-adenosylhomocysteine (AdoHcy) and sarcosine (N-methylglycine).	Glycine	153-160	glycine N-methyltransferase	Homo sapiens	0-4
9655337-3	1998	To investigate the role of the helical domain, we engineered a variant of I-FABP by deleting 17 contiguous residues and inserting a Ser-Gly linker (Kim K et al., 1996, Biochemistry 35:7553-7558).	Glycine	136-139	fatty acid binding protein 2	Homo sapiens	74-80
9671146-4	1998	We describe the successful engineering, expression and pre-clinical characterisation of a phosphorylatable "kemptide" (Leu-Arg-Arg-Ala-Ser-Gly) anti-carcinoembryonic antigen (anti-CEA) scFv (PKS-scFv), for use as a radioimmunotherapeutic agent.	Glycine	139-142	immunglobulin heavy chain variable region	Homo sapiens	185-189
9671146-4	1998	We describe the successful engineering, expression and pre-clinical characterisation of a phosphorylatable "kemptide" (Leu-Arg-Arg-Ala-Ser-Gly) anti-carcinoembryonic antigen (anti-CEA) scFv (PKS-scFv), for use as a radioimmunotherapeutic agent.	Glycine	139-142	immunglobulin heavy chain variable region	Homo sapiens	191-199
9607849-0	1998	Glycine-valine dimorphism at the 86th amino acid of HLA-DRB1 influenced the prognosis of postschistosomal hepatic fibrosis.	Glycine	0-7	major histocompatibility complex, class II, DR beta 1	Homo sapiens	52-60
9556561-1	1998	The nucleolar proteins Gar1p and fibrillarin possess a typical nucleolar glycine/arginine-rich domain and belong to ribonucleoprotein particles.	Glycine	73-80	H/ACA snoRNP pseudouridylase subunit GAR1	Saccharomyces cerevisiae S288C	23-28
9538117-4	1998	Using single stranded conformational polymorphism (SSCP) and DNA sequencing analysis, we have identified an ER containing a point mutation at position 415 (gly to val) within the hormone binding domain.	Glycine	156-159	estrogen receptor 1	Homo sapiens	108-110
9582270-5	1998	The verprolin-homology region in N-WASP was required for binding to the glycine-rich repeats domain of VirG, an essential domain for recruitment of F-actin on intracellular S.flexneri.	Glycine	72-79	WASP like actin nucleation promoting factor S homeolog	Xenopus laevis	33-39
9531562-2	1998	The formation of a fibronectin matrix is a dynamic, cell-mediated process that involves both ligation of the alpha5beta1 integrin with the Arg-Gly-Asp (RGD) sequence in fibronectin and binding of the amino terminus of fibronectin to cell surface receptors, termed "matrix assembly sites," which mediate the assembly of soluble fibronectin into insoluble fibrils.	Glycine	143-146	fibronectin 1	Homo sapiens	19-30
9539726-4	1998	Light activation of rhodopsin causes a dramatic shift from a disordered conformation of Gtalpha(340-350) to a binding motif with a helical turn followed by an open reverse turn centered at Gly-348, a helix-terminating C capping motif of an alphaL type.	Glycine	189-192	rhodopsin	Homo sapiens	20-29
9531562-2	1998	The formation of a fibronectin matrix is a dynamic, cell-mediated process that involves both ligation of the alpha5beta1 integrin with the Arg-Gly-Asp (RGD) sequence in fibronectin and binding of the amino terminus of fibronectin to cell surface receptors, termed "matrix assembly sites," which mediate the assembly of soluble fibronectin into insoluble fibrils.	Glycine	143-146	fibronectin 1	Homo sapiens	169-180
9531562-2	1998	The formation of a fibronectin matrix is a dynamic, cell-mediated process that involves both ligation of the alpha5beta1 integrin with the Arg-Gly-Asp (RGD) sequence in fibronectin and binding of the amino terminus of fibronectin to cell surface receptors, termed "matrix assembly sites," which mediate the assembly of soluble fibronectin into insoluble fibrils.	Glycine	143-146	fibronectin 1	Homo sapiens	169-180
9531562-2	1998	The formation of a fibronectin matrix is a dynamic, cell-mediated process that involves both ligation of the alpha5beta1 integrin with the Arg-Gly-Asp (RGD) sequence in fibronectin and binding of the amino terminus of fibronectin to cell surface receptors, termed "matrix assembly sites," which mediate the assembly of soluble fibronectin into insoluble fibrils.	Glycine	143-146	fibronectin 1	Homo sapiens	169-180
9787767-7	1998	Turtle WT1, like those of the alligator, chicken, and Xenopus lacks the proline- and glycine-rich stretches that are present in mammalian WT1.	Glycine	85-92	WT1 transcription factor	Homo sapiens	138-141
9525872-0	1998	A Gly --&gt; Ser change causes defective folding in vitro of calcium-binding epidermal growth factor-like domains from factor IX and fibrillin-1.	Glycine	2-5	coagulation factor IX	Homo sapiens	119-128
9525872-2	1998	A mutation that changes a highly conserved Gly residue to Ser in this domain has been identified both in the factor IX (FIX) and fibrillin-1 genes, where it is associated with relatively mild variants of hemophilia B and Marfan syndrome, respectively.	Glycine	43-46	coagulation factor IX	Homo sapiens	109-118
9525933-6	1998	Homogenates of nematodes and immunopurified preparations of the recombinant GLY proteins demonstrated that worms express functional ppGaNTase enzymes (GLY-3, GLY-4, GLY-5A, GLY-5B, and GLY-5C), which can O-glycosylate mammalian apomucin peptide sequences in vitro.	Glycine	76-79	Glyco_trans_2-like domain-containing protein;Polypeptide N-acetylgalactosaminyltransferase 4	Caenorhabditis elegans	158-163
9490687-8	1998	Arg517 is part of the Arg-Gly-Asp(RGD) sequence in thrombin and contributes to an ion cluster with aspartic acid residues 552 and 554.	Glycine	26-29	coagulation factor II, thrombin	Homo sapiens	51-59
9506952-2	1998	Myristoylation is catalyzed by an enzyme activity, N-myristoyltransferase (NMT), which transfers myristic acid from myristoyl coenzyme A to the amino group of a protein"s N-terminal glycine residue.	Glycine	182-189	N-myristoyltransferase 1	Homo sapiens	51-73
9506952-2	1998	Myristoylation is catalyzed by an enzyme activity, N-myristoyltransferase (NMT), which transfers myristic acid from myristoyl coenzyme A to the amino group of a protein"s N-terminal glycine residue.	Glycine	182-189	N-myristoyltransferase 1	Homo sapiens	75-78
9568912-0	1998	The dimerization motif of the glycophorin A transmembrane segment in membranes: importance of glycine residues.	Glycine	94-101	glycophorin A (MNS blood group)	Homo sapiens	30-43
9501171-5	1998	Five REGalpha mutants that remain inactive in the mixing assay contain amino acid substitutions clustered between Arg-141 and Gly-149.	Glycine	126-129	proteasome activator subunit 1	Homo sapiens	5-13
9546654-6	1998	Pharmacological characterization of crude membrane preparations of the recombinant yeast cells showed saturable binding of the glycine antagonist [3H]MDL105,519 with Kd values of 56.9 +/- 6.19 nM (NR1a/NR2A), 26.72 +/- 2.13 nM (NR1a/NR2B), and 21.22 +/- 1.64 nM (NR1a/NR2C), and bound capacities of 17.94 +/- 1.24 pmol/mg membrane protein (NR1a/NR2A), 11.45 +/- 0.67 pmol/mg (NR1a/NR2B), and 16.15 +/- 0.86 (NR1a/NR2C) pmol/mg.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	202-206
9494104-7	1998	Expression of Mas-DH+Gly in strains deficient in either the Mkc7 or the Yap3 protease reduced proteolysis, while no proteolysis of Mas-DH+Gly was detectable in a strain lacking both proteases.	Glycine	21-24	Yap3p	Saccharomyces cerevisiae S288C	72-76
9546654-6	1998	Pharmacological characterization of crude membrane preparations of the recombinant yeast cells showed saturable binding of the glycine antagonist [3H]MDL105,519 with Kd values of 56.9 +/- 6.19 nM (NR1a/NR2A), 26.72 +/- 2.13 nM (NR1a/NR2B), and 21.22 +/- 1.64 nM (NR1a/NR2C), and bound capacities of 17.94 +/- 1.24 pmol/mg membrane protein (NR1a/NR2A), 11.45 +/- 0.67 pmol/mg (NR1a/NR2B), and 16.15 +/- 0.86 (NR1a/NR2C) pmol/mg.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	345-349
9566852-1	1998	HOE 901 is a new biosynthetic long-acting human insulin analog (GLY[A21]ARG[B31]ARG[B32]).	Glycine	64-67	insulin	Homo sapiens	48-55
9551089-17	1998	Substitution with glycine allows insulin binding, but does not activate normally glucose transport, further supporting an essential role of this position in the initiation of insulin receptor signalling of glucose transport.	Glycine	18-25	insulin	Cricetulus griseus	33-40
9551089-17	1998	Substitution with glycine allows insulin binding, but does not activate normally glucose transport, further supporting an essential role of this position in the initiation of insulin receptor signalling of glucose transport.	Glycine	18-25	insulin	Cricetulus griseus	175-182
9570506-2	1998	Here, we tested whether tTGase is involved during HT-1080 fibrosarcoma cell apoptosis induced by the YIGSR (Tyr-Ile-Gly-Ser-Arg) peptide.	Glycine	116-119	transglutaminase 2	Homo sapiens	24-30
9582105-1	1998	Recently, a molecular variant of alpha-adducin (with tryptophan instead of glycine at amino acid number 460) has been reported to be more common among Italian and French hypertensive individuals than among controls.	Glycine	75-82	adducin 1	Homo sapiens	33-46
9501915-1	1998	N-myristoyl transferase (NMT) catalyzes the transfer of the fatty acid myristate from myristoyl-CoA to the N-terminal glycine of substrate proteins, and is found only in eukaryotic cells.	Glycine	118-125	N-myristoyltransferase 1	Homo sapiens	0-23
9501915-1	1998	N-myristoyl transferase (NMT) catalyzes the transfer of the fatty acid myristate from myristoyl-CoA to the N-terminal glycine of substrate proteins, and is found only in eukaryotic cells.	Glycine	118-125	N-myristoyltransferase 1	Homo sapiens	25-28
9448300-8	1998	A glycine-to-arginine missense mutation (G185R) was present in the b Nramp2 gene, but not in the normal allele.	Glycine	2-9	solute carrier family 11 member 2	Rattus norvegicus	69-75
9630436-3	1998	IA-4 cDNA is 1,007 bp in length and predicts a protein of 187 amino acids with a molecular mass of 19,940 D. Examination of the amino acid sequence showed a high content of arginine (18.7%), proline (14.4%), alanine (16.0%), leucine (13.4%) and glycine (9.6%).	Glycine	245-252	proprotein convertase subtilisin/kexin type 1 inhibitor	Mus musculus	0-4
9538234-3	1998	The protein, named JKTBP, contains two repeats of a putative RNA binding domain (RBD), each composed of canonical RNP-2 and RNP-1 motifs, and a glycine- and tyrosine-rich carboxyl terminus.	Glycine	144-151	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	19-24
9461491-7	1998	The low Km and high kcat values (Km 7.3 and 5.0 microM, kcat 226 and 207 s-1 for the hydrolysis of Phe-Ser-Pro-Arg-Leu-Gly-Lys-Arg and Phe-Ser-Pro-Arg-Leu-Gly-Arg-Arg, respectively) obtained for the hydrolysis of these two peptides by insect ACE means that these peptides, along with mammalian bradykinin, are the most favoured in vitro ACE substrates so far identified.	Glycine	119-122	angiotensin I converting enzyme	Homo sapiens	242-245
9461491-7	1998	The low Km and high kcat values (Km 7.3 and 5.0 microM, kcat 226 and 207 s-1 for the hydrolysis of Phe-Ser-Pro-Arg-Leu-Gly-Lys-Arg and Phe-Ser-Pro-Arg-Leu-Gly-Arg-Arg, respectively) obtained for the hydrolysis of these two peptides by insect ACE means that these peptides, along with mammalian bradykinin, are the most favoured in vitro ACE substrates so far identified.	Glycine	119-122	kininogen 1	Homo sapiens	294-304
9461491-7	1998	The low Km and high kcat values (Km 7.3 and 5.0 microM, kcat 226 and 207 s-1 for the hydrolysis of Phe-Ser-Pro-Arg-Leu-Gly-Lys-Arg and Phe-Ser-Pro-Arg-Leu-Gly-Arg-Arg, respectively) obtained for the hydrolysis of these two peptides by insect ACE means that these peptides, along with mammalian bradykinin, are the most favoured in vitro ACE substrates so far identified.	Glycine	119-122	angiotensin I converting enzyme	Homo sapiens	337-340
9449725-4	1998	This novel CTL line was used to investigate whether the epitope (positions 509-517 in EBNA-1, presented through Kd) was presented to CTL by mouse cells expressing full-length EBNA-1 or a deletion mutant of EBNA-1, lacking the Glycine-Alanine (Gly-Ala)-rich region.	Glycine	226-233	EBNA-1	Human gammaherpesvirus 4	86-92
9449725-4	1998	This novel CTL line was used to investigate whether the epitope (positions 509-517 in EBNA-1, presented through Kd) was presented to CTL by mouse cells expressing full-length EBNA-1 or a deletion mutant of EBNA-1, lacking the Glycine-Alanine (Gly-Ala)-rich region.	Glycine	226-229	EBNA-1	Human gammaherpesvirus 4	86-92
9449725-6	1998	These results suggest that epitopes from full-length EBNA-1 are poorly presented, and that the Gly-Ala-rich region is responsible for this phenomenon.	Glycine	95-98	EBNA-1	Human gammaherpesvirus 4	53-59
9430676-7	1998	Unexpectedly, we found that a glycine-rich region of p105 that is required for p105 processing in mammalian cells is not required for processing in yeast.	Glycine	30-37	nuclear factor kappa B subunit 1	Homo sapiens	53-57
9444982-4	1998	Furthermore, using an in vitro trans-cleavage assay, we defined the proteolytic cleavage site at the carboxyl terminus of p9 as pp1a-pp1ab amino acids Gly-111 and Asn-112.	Glycine	151-154	protein phosphatase 1 catalytic subunit alpha	Homo sapiens	128-132
9491993-1	1998	In studying chimeras of NR2A and NR2C subunits of the NMDA receptor, we have found that glycine-independent desensitization depends on two regions of the extracellular N-terminal domain.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	24-28
9511806-6	1998	However, partial N-terminal amino acid sequence analysis of recombinant QPs1 shows two extra amino acid residues, glycine and serine, at the N-terminus of mature QPs1, resulting from the recombinant manipulation.	Glycine	114-121	succinate dehydrogenase complex subunit C	Bos taurus	72-76
9532789-6	1998	This lysozyme has an extra Gly residue at N-terminus, which was found in pheasant lysozyme.	Glycine	27-30	lysozyme	Homo sapiens	5-13
9532789-6	1998	This lysozyme has an extra Gly residue at N-terminus, which was found in pheasant lysozyme.	Glycine	27-30	lysozyme	Homo sapiens	82-90
9532789-7	1998	Further, this lysozyme has an insertion of a Gly residue between 47 and 48 residues when compared with chicken lysozyme, as found in human lysozyme, therefore it proved that this lysozyme has the largest number of amino acids (131 aa) in chicken type lysozymes.	Glycine	45-48	lysozyme	Homo sapiens	14-22
9495830-5	1998	Elimination of this sidechain by mutation to glycine produces a v-Src kinase which preferentially utilizes N6-(benzyl) ATP as a phosphodonor substrate.	Glycine	45-52	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	66-69
9754041-9	1998	Non-bulky amino acids like glycine, alanine and serine with low specific rotation are present in greater number in the primitive form of calmodulin and have been significantly reduced in highly evolved form of calmodulin, suggesting that their requirement was insignificant and were eliminated from EF hand structure during evolution.	Glycine	27-34	calmodulin 1	Homo sapiens	137-147
9754041-9	1998	Non-bulky amino acids like glycine, alanine and serine with low specific rotation are present in greater number in the primitive form of calmodulin and have been significantly reduced in highly evolved form of calmodulin, suggesting that their requirement was insignificant and were eliminated from EF hand structure during evolution.	Glycine	27-34	calmodulin 1	Homo sapiens	210-220
9430676-7	1998	Unexpectedly, we found that a glycine-rich region of p105 that is required for p105 processing in mammalian cells is not required for processing in yeast.	Glycine	30-37	nuclear factor kappa B subunit 1	Homo sapiens	79-83
9753141-3	1998	Most (78%) of the neurones with GluR1-immunoreactivity were GABA-immunoreactive, and some of these were also glycine-immunoreactive, whereas nearly all (97%) of the GluR2/3-immunoreactive neurones were not GABA- or glycine-immunoreactive.	Glycine	215-222	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	32-37
9422720-0	1998	The roles of glycine residues in the ATP binding site of human brain hexokinase.	Glycine	13-20	hexokinase 1	Homo sapiens	69-79
9871463-4	1998	Glycine shows different affinities at various NMDA receptor subtypes probably via to allosteric interactions between NMDA2 subunits and the glycine recognition site on the NMDAR1 subunit.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	172-178
9871463-4	1998	Glycine shows different affinities at various NMDA receptor subtypes probably via to allosteric interactions between NMDA2 subunits and the glycine recognition site on the NMDAR1 subunit.	Glycine	140-147	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	172-178
9600458-5	1998	We identified a unique point mutation in each proband, which resulted in substitutions for glycine residues in a 300-aa region of the alpha1(I) helix, specifically, Gly to Ala at codon 220 (GGT--&gt;GCT), Gly to Cys at codon 349 (GGT--&gt;TGT) and Gly to Cys at codon 523 (GGT--&gt;TGT).	Glycine	91-98	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	239-242
9600458-5	1998	We identified a unique point mutation in each proband, which resulted in substitutions for glycine residues in a 300-aa region of the alpha1(I) helix, specifically, Gly to Ala at codon 220 (GGT--&gt;GCT), Gly to Cys at codon 349 (GGT--&gt;TGT) and Gly to Cys at codon 523 (GGT--&gt;TGT).	Glycine	91-98	queuine tRNA-ribosyltransferase catalytic subunit 1	Homo sapiens	282-285
9506823-1	1998	The synthetic nonapeptide Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys corresponding to the amino acid sequence 163-171 of human interleukin-1beta (IL-1beta) has been reported to retain considerable immunostimulatory activity of the native protein without the induction of the inflammatory or pyrogenic responses.	Glycine	34-37	interleukin 1 beta	Homo sapiens	120-137
9506823-1	1998	The synthetic nonapeptide Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys corresponding to the amino acid sequence 163-171 of human interleukin-1beta (IL-1beta) has been reported to retain considerable immunostimulatory activity of the native protein without the induction of the inflammatory or pyrogenic responses.	Glycine	34-37	interleukin 1 beta	Homo sapiens	139-147
9396761-4	1997	Mutation of the single Arg-Gly-Asp (RGD) motif in human L1-Ig6 effectively abrogated binding by the aforementioned integrins.	Glycine	27-30	L1 cell adhesion molecule	Homo sapiens	56-62
9662733-4	1998	We have shown that effect of vasopressin on consolidation is significantly reduced by noncompetitive antagonist of ion channel in the NMDA receptor--dizocilpine (MK-801) and competitive antagonist of glycine recognization site--HA-966.	Glycine	200-207	arginine vasopressin	Homo sapiens	29-40
9481670-10	1998	Substitutions of glycine, serine, glutamine or aspartate for the N-site asparagine in the NR1-subunit enhanced the extent of block over intermediate potentials but left the voltage dependence of the block unchanged indicating that structural determinants of the block remained.	Glycine	17-24	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	90-93
9481670-13	1998	In channels containing substitutions of glycine, serine or glutamine for the N-site asparagine in the NR2A-subunit, the block Mg2+ was reduced at negative potentials.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	102-106
9425317-3	1997	The peptides, Arg-Gly-Asp (RGD) and Glu-Ile-Leu-Asp-Val (EILDV) which were reported as active fragments of Fibronectin (a cell adhesion protein), were conjugated with aaPEG (molecular weight, 10,000).	Glycine	18-21	fibronectin 1	Homo sapiens	107-118
9393748-3	1997	Galectin-3 contains the NWGR amino acid sequence highly conserved in the BH1 domain of the bcl-2 gene family, and a substitution of glycine to alanine in this motif abrogated its antiapoptotic activity.	Glycine	132-139	BCL2 apoptosis regulator	Homo sapiens	91-96
9391044-0	1997	The C9 methyl group of retinal interacts with glycine-121 in rhodopsin.	Glycine	46-53	rhodopsin	Homo sapiens	61-70
9390183-1	1997	Myristoyl-CoA:protein N-myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the cotranslational transfer of myristate to the NH2-terminal glycine residue of a number of important proteins of diverse function.	Glycine	162-169	N-myristoyltransferase 1	Homo sapiens	46-49
9440002-6	1997	Furthermore, we show that beta branched residues, in conjunction with Gly residues in the c-erbB-2 sequence, act as destabilizers for the alpha helix structure, pi deformations are tightly related to other local structural motifs found in soluble and membrane proteins.	Glycine	70-73	erb-b2 receptor tyrosine kinase 2	Homo sapiens	90-98
9395478-2	1997	Cells adhere to the extracellular matrix proteins fibronectin and tenascin in part by the interaction of certain integrins with the Arg-Gly-Asp (RGD) sequence, displayed on specific FNIII repeats.	Glycine	136-139	fibronectin 1	Homo sapiens	50-61
9398220-9	1997	In our study, the SHM1 and SHM2 genes were disrupted singly and in combination to investigate the contributions of the two SHMT isozymes to the production of glycine and one-carbon units required in purine biosynthesis.	Glycine	158-165	glycine hydroxymethyltransferase SHM1	Saccharomyces cerevisiae S288C	18-22
9353336-1	1997	N-Myristoyltransferase (NMT) catalyzes the cotranslational acylation with myristic acid of the NH2-terminal glycines of a number of cellular and viral proteins.	Glycine	108-116	N-myristoyltransferase 1	Homo sapiens	0-22
9375665-4	1997	Brief application of an NMDA/glycine solution to cells markedly increased intracellular calcium in cells transfected with NR1/NR2A, NR1/NR2B, or NR1/NR2A/NR2B as measured by fura-2 calcium imaging.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	122-125
9375665-4	1997	Brief application of an NMDA/glycine solution to cells markedly increased intracellular calcium in cells transfected with NR1/NR2A, NR1/NR2B, or NR1/NR2A/NR2B as measured by fura-2 calcium imaging.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	126-130
9375665-4	1997	Brief application of an NMDA/glycine solution to cells markedly increased intracellular calcium in cells transfected with NR1/NR2A, NR1/NR2B, or NR1/NR2A/NR2B as measured by fura-2 calcium imaging.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	132-135
9375665-4	1997	Brief application of an NMDA/glycine solution to cells markedly increased intracellular calcium in cells transfected with NR1/NR2A, NR1/NR2B, or NR1/NR2A/NR2B as measured by fura-2 calcium imaging.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	132-135
9375665-4	1997	Brief application of an NMDA/glycine solution to cells markedly increased intracellular calcium in cells transfected with NR1/NR2A, NR1/NR2B, or NR1/NR2A/NR2B as measured by fura-2 calcium imaging.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	149-153
9520641-3	1997	An additional glycine residue was attached to the C-terminus of previously isolated eel ANP.	Glycine	14-21	natriuretic peptide A	Homo sapiens	88-91
9548480-7	1997	In contrast, the leech alpha-MSH was flanked at its C-terminal by the Gly-Arg-Lys amidation signal.	Glycine	70-73	proopiomelanocortin	Homo sapiens	23-32
9353336-1	1997	N-Myristoyltransferase (NMT) catalyzes the cotranslational acylation with myristic acid of the NH2-terminal glycines of a number of cellular and viral proteins.	Glycine	108-116	N-myristoyltransferase 1	Homo sapiens	24-27
9395067-3	1997	In addition to this domain, Rvs167p contains a central glycine-proline-alanine rich domain and a SH3 domain.	Glycine	55-62	amphiphysin	Saccharomyces cerevisiae S288C	28-35
9385367-1	1997	The human androgen receptor gene (hAR) has a long, polymorphic trinucleotide (GGN; glycine)n repeat in the 3" portion of its first exon, with n = 10-31.	Glycine	83-90	androgen receptor	Homo sapiens	10-27
9352860-0	1997	Glycine-extended gastrin acts as an autocrine growth factor in a nontransformed colon cell line.	Glycine	0-7	gastrin	Mus musculus	17-24
9352860-9	1997	CONCLUSIONS: YAMC cells use nonamidated progastrin-derived peptides as autocrine growth factors, partly through binding to an extracellular receptor selective for glycine-extended gastrin, and partly through an intracellular mechanism.	Glycine	163-170	gastrin	Mus musculus	43-50
9385367-1	1997	The human androgen receptor gene (hAR) has a long, polymorphic trinucleotide (GGN; glycine)n repeat in the 3" portion of its first exon, with n = 10-31.	Glycine	83-90	gametogenetin	Homo sapiens	78-81
9387867-0	1997	Characterization of glycine release mediated by glycine transporter 1 stably expressed in HEK-293 cells.	Glycine	20-27	solute carrier family 6 member 9	Homo sapiens	48-69
9312102-2	1997	Using chimeric NR2A/NR2B subunits, we have located a region of NR2B (amino acids 138-238) which regulated glycine-independent polyamine stimulation.	Glycine	106-113	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	15-19
9369230-9	1997	Hence, the increase of glycine-extended gastrin in combination with normal levels of carboxyamidated gastrin suggests that G-cells may have another biosynthetic pathway for gastrin.	Glycine	23-30	gastrin	Mus musculus	40-47
9316505-6	1997	A 120-kDa chymotryptic fragment of fibronectin containing the Arg-Gly-Asp peptide sequence was able to reproduce the effects of the whole fibronectin molecule.	Glycine	66-69	fibronectin 1	Homo sapiens	35-46
9370259-5	1997	The C-terminal region of S. mansoni YB-1 differs from the other Y-box binding proteins because of the presence of tandem repeats of Arg and Gly, suggesting the formation of a fibroin-like beta-sandwich structure.	Glycine	140-143	Y-box binding protein 1	Homo sapiens	36-40
9348444-10	1997	Moreover, the 3-fold increase in TNF alpha mRNA caused by WY-14,643 was blocked completely by the glycine-enriched diet.	Glycine	98-105	tumor necrosis factor	Rattus norvegicus	33-42
9348444-11	1997	Similarly, immunohistochemical staining for TNF alpha was increased 6-fold by WY-14,643, an increase which was prevented by dietary glycine.	Glycine	132-139	tumor necrosis factor	Rattus norvegicus	44-53
9348444-13	1997	These data demonstrate that a glycine-enriched diet prevents stimulated cell proliferation most likely by inhibiting TNF alpha production and raise the possibility that dietary glycine will be effective in preventing cancer caused by nongenotoxic carcinogens such as WY-14,643.	Glycine	30-37	tumor necrosis factor	Rattus norvegicus	117-126
9376072-4	1997	One of these, p542, encodes a glycine rich 28-mer which constitutes its cross-reactive epitope, as shown elsewhere.	Glycine	30-37	RALY heterogeneous nuclear ribonucleoprotein	Homo sapiens	14-18
9299613-9	1997	First, in the yeast two-hybrid system we mapped two interactive N-terminal regions of EBNA-1, aa 40-60 and aa 325-376, each of which contains arginine-glycine repeats.	Glycine	151-158	EBNA-1	Human gammaherpesvirus 4	86-92
9311595-8	1997	These data demonstrate that peptide vaccination with a single mutant p21-ras-derived peptide induces CD4+ and CD8+ CTL specific for nested epitopes, including the Gly --&gt; Val substitution at codon 12, and that both these T-cell sub-sets specifically recognize tumour cells harbouring the corresponding K-ras mutation.	Glycine	163-166	CD4 molecule	Homo sapiens	101-104
9316505-6	1997	A 120-kDa chymotryptic fragment of fibronectin containing the Arg-Gly-Asp peptide sequence was able to reproduce the effects of the whole fibronectin molecule.	Glycine	66-69	fibronectin 1	Homo sapiens	138-149
9815849-0	1997	Androgen receptor variants with short glutamine or glycine repeats may identify unique subpopulations of men with prostate cancer.	Glycine	51-58	androgen receptor	Homo sapiens	0-17
9291099-3	1997	The fourth SCR of both proteins (SCR 4) includes the sequence Arg-Gly-Asp (RGD), a motif that is responsible for the major adhesive activity of matrix proteins like fibronectin.	Glycine	66-69	fibronectin 1	Homo sapiens	165-176
9815849-1	1997	The androgen receptor (AR) contains glutamine (CAG) and glycine (GGC) repeats that are each polymorphic in length.	Glycine	56-63	androgen receptor	Homo sapiens	4-21
9815849-1	1997	The androgen receptor (AR) contains glutamine (CAG) and glycine (GGC) repeats that are each polymorphic in length.	Glycine	56-63	androgen receptor	Homo sapiens	23-25
9815849-10	1997	The odds of having a germ-line AR gene with a short glycine repeat (&lt;/=14 GGCs) were substantially higher in men with prostate cancer than in the general population, but the frequency of alleles with a short GGC repeat was the same in men with lymph node-positive versus lymph node-negative disease.	Glycine	52-59	androgen receptor	Homo sapiens	31-33
9253359-5	1997	In this report, genetic analysis of 1 Japanese NSHPT family revealed 2 novel mutations at codon 185 (CGA-->TGA/Arg-->Ter) in exon 4 of the Casr gene and at codon 670 (GGG-->GAG/Gly-->Glu) in exon 7.	Glycine	177-180	calcium sensing receptor	Homo sapiens	47-52
9268623-4	1997	Lungfish insulin also contains amino acid substitutions such as Gly --&gt; Ala at position B-21, Glu --&gt; Asp at position B-22, and a Lys --&gt; Ser residue at position B-30, previously found in insulins from amphibia.	Glycine	64-67	insulin	Homo sapiens	9-16
9606832-1	1997	Heparin was studied for its effect on the hydrolysis time of clots from desAA fibrin (FB), desAABB fibrin (F0) and fibrinogen (Fg) of a bull and a man by gly-or lys-plasminogen which is activated by the tissue activator.	Glycine	154-157	fibrinogen beta chain	Homo sapiens	127-129
9253359-5	1997	In this report, genetic analysis of 1 Japanese NSHPT family revealed 2 novel mutations at codon 185 (CGA-->TGA/Arg-->Ter) in exon 4 of the Casr gene and at codon 670 (GGG-->GAG/Gly-->Glu) in exon 7.	Glycine	177-180	calcium sensing receptor	Homo sapiens	139-143
9211865-2	1997	The high affinity interaction of integrin alpha5beta1 with the central cell binding domain (CCBD) of fibronectin requires both the Arg-Gly-Asp (RGD) sequence (in the 10th type III repeat) and a second site (in the adjacent 9th type III repeat) which synergizes with RGD.	Glycine	135-138	fibronectin 1	Homo sapiens	101-112
9220968-2	1997	The C-terminal extracellular domain of BP180 contains 15 domains composed of Gly-X-Y tandem repeats, which are predicted to form collagen-like triple helices.	Glycine	77-80	collagen type XVII alpha 1 chain	Homo sapiens	39-44
16728118-8	1997	Catalase decreased (P &lt; 0.05) the percentage of membrane-intact spermatozoa at 24 h. Motility and membrane integrity of spermatozoa after dilution with glycin extender containing catalase did not differ from the controls.	Glycine	155-161	catalase	Homo sapiens	0-8
9218437-5	1997	The predominant amino acids detected by protein sequence analysis following cleavage of insoluble elastin with HME, MME, and 92-kDa gelatinase were Leu, Ile, Ala, Gly, and Val.	Glycine	163-166	membrane metalloendopeptidase	Homo sapiens	116-119
9195901-6	1997	By using two independent methods we demonstrate intracellular Abeta1-42 as well as Abetax-42 but less Abetax-40 and Abeta1-40 in kidney 293 cells stably transfected with wild type beta-amyloid precursor protein (betaAPP) or the FAD-associated Val/Gly mutation.	Glycine	247-250	amyloid beta precursor protein	Homo sapiens	212-219
9199447-4	1997	Purified human fibrinogen and peptides containing the sequence Arg-Gly-Asp (RGD) were also found to promote bacterial invasion of cultured cells.	Glycine	67-70	fibrinogen beta chain	Homo sapiens	15-25
9261960-5	1997	SAA pI 8.0 was found to have isoleucine in Position 16, glutamine in Position 44 and glycine in Position 59.	Glycine	85-92	serum amyloid A protein	Equus caballus	0-3
9219327-6	1997	Endothelial membrane/matrix and detergent-soluble fractions of human placenta were screened for the ability to bind vWF by electrophoresis of extracts on SDS-polyacrylamide gels, electrotransferring to nitrocellulose and probing with fluid-phase 125I-labeled vWF or a 39/34-kDa vWF fragment (Leu-480-Gly-718) that encompasses the A1 domain.	Glycine	300-303	von Willebrand factor	Homo sapiens	116-119
9218791-8	1997	Mutation of a conserved leucine at position 2 in the presequence to a glycine disrupts import of pFd into the organelle.	Glycine	70-77	complement factor properdin	Homo sapiens	97-100
9169519-4	1997	We show that glycine uptake by GLYT1b dramatically reduces NMDAR currents by reducing the glycine concentration in extracellular spaces in which diffusion is restricted.	Glycine	13-20	solute carrier family 6 member 9 S homeolog	Xenopus laevis	31-37
9169519-4	1997	We show that glycine uptake by GLYT1b dramatically reduces NMDAR currents by reducing the glycine concentration in extracellular spaces in which diffusion is restricted.	Glycine	90-97	solute carrier family 6 member 9 S homeolog	Xenopus laevis	31-37
9188478-10	1997	Also based upon the computer model, we have designed and produced a mutant of human carboxypeptidase A1, changed at position 268 from the wild type threonine to a glycine (hCPA1-T268G).	Glycine	163-170	carboxypeptidase A1	Homo sapiens	84-103
9188478-10	1997	Also based upon the computer model, we have designed and produced a mutant of human carboxypeptidase A1, changed at position 268 from the wild type threonine to a glycine (hCPA1-T268G).	Glycine	163-170	carboxypeptidase A1	Homo sapiens	172-177
9200692-3	1997	Kinetic analysis indicated that antithrombin (AT with P2 Gly) inhibited thrombin L99Y, 14.1- and 5.5-fold slower than thrombin in the absence and presence of heparin, respectively.	Glycine	57-60	coagulation factor II, thrombin	Homo sapiens	36-44
9200692-3	1997	Kinetic analysis indicated that antithrombin (AT with P2 Gly) inhibited thrombin L99Y, 14.1- and 5.5-fold slower than thrombin in the absence and presence of heparin, respectively.	Glycine	57-60	coagulation factor II, thrombin	Homo sapiens	72-80
9166417-8	1997	Glycine substitutions in either EMB-9 or LET-2 cause intracellular accumulation of both chains.	Glycine	0-7	Collagen alpha-2(IV) chain	Caenorhabditis elegans	41-46
9227496-7	1997	Moreover, tumor necrosis factor-alpha (TNF-alpha) production in cultured Kupffer cells due to LPS was decreased significantly by glycine.	Glycine	129-136	tumor necrosis factor	Homo sapiens	10-37
9227496-7	1997	Moreover, tumor necrosis factor-alpha (TNF-alpha) production in cultured Kupffer cells due to LPS was decreased significantly by glycine.	Glycine	129-136	tumor necrosis factor	Homo sapiens	39-48
9186907-7	1997	Structural integrity of the conserved His-Gly dipeptide of lipases also appears to be important for neutral lipid hydrolysis, as replacement of His65 by glutamine abolished HLAL and HGL enzymic activity.	Glycine	42-45	lipase F, gastric type	Homo sapiens	182-185
9151692-3	1997	The cirp cDNA encoded an 18-kD protein consisting of an amino-terminal RNAbinding domain and a carboxyl-terminal glycine-rich domain and exhibited structural similarity to a class of stress-induced RNA-binding proteins found in plants.	Glycine	113-120	cold inducible RNA binding protein	Homo sapiens	4-8
9163906-0	1997	Identification of Saccharomyces cerevisiae GLY1 as a threonine aldolase: a key enzyme in glycine biosynthesis.	Glycine	89-96	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	43-47
9163906-4	1997	Growth experiments using glucose as the sole carbon source showed that GLY1 is more important for glycine biosynthesis than SHM1 and SHM2 encoding alternative serine hydroxymethyltransferases.	Glycine	98-105	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	71-75
9164995-3	1997	TDH activity was determined as aminoacetone and glycine accumulation during incubation of liver mitochondria.	Glycine	48-55	L-threonine dehydrogenase (pseudogene)	Gallus gallus	0-3
9164995-9	1997	In two other experiments, the activity of TDH was investigated in chicks fed for 9 d dietary supplements of either serine or glycine (5.5 or 4 g/100 g basal diet, respectively).	Glycine	125-132	L-threonine dehydrogenase (pseudogene)	Gallus gallus	42-45
9179600-1	1997	Two membrane-localized transporter proteins (GLYT1 and GLYT2) are responsible for removal of extracellular glycine in the mammalian CNS.	Glycine	107-114	solute carrier family 6 member 9	Homo sapiens	45-50
9213246-1	1997	The human hepatocellular carcinoma (HCC) cell line, HLF, expresses only mutant-type p53 (mt-p53), which has an amino acid substitution at the 244th residue from glycine to alanine.	Glycine	161-168	tumor protein p53	Homo sapiens	84-87
9213246-1	1997	The human hepatocellular carcinoma (HCC) cell line, HLF, expresses only mutant-type p53 (mt-p53), which has an amino acid substitution at the 244th residue from glycine to alanine.	Glycine	161-168	tumor protein p53	Homo sapiens	92-95
9294860-4	1997	The synaptic action of glycine is terminated by two sodium- and chloride-coupled transporters, GLYT1 and GLYT2, located in the glial plasma membrane and in the presynaptic terminals, respectively.	Glycine	23-30	solute carrier family 6 member 9	Homo sapiens	95-100
9154965-1	1997	MyristoylCoA:protein N-myristoyltransferase (NMT) covalently attaches the 14-carbon saturated fatty acid myristate, via an amide bond, to the N-terminal glycine residues of a variety of cellular proteins.	Glycine	153-160	N-myristoyltransferase 1	Homo sapiens	21-43
9154965-1	1997	MyristoylCoA:protein N-myristoyltransferase (NMT) covalently attaches the 14-carbon saturated fatty acid myristate, via an amide bond, to the N-terminal glycine residues of a variety of cellular proteins.	Glycine	153-160	N-myristoyltransferase 1	Homo sapiens	45-48
9272740-0	1997	Osteogenesis imperfecta phenotypes resulting from serine for glycine substitutions in the alpha2(I) collagen chain.	Glycine	61-68	collagen type I alpha 2 chain	Homo sapiens	90-108
9272740-1	1997	Clinical and biochemical findings in 5 unrelated patients with osteogenesis imperfecta (OI) with a serine for glycine substitution in the alpha2(I) collagen chain are presented.	Glycine	110-117	collagen type I alpha 2 chain	Homo sapiens	138-156
9272740-3	1997	Findings show that the phenotypic severity of serine for glycine substitutions in the alpha2(I) collagen chain is region dependent similar to the observations for the alpha1(I) collagen chain, and that so-called "lethal" and "non-lethal" domains in the alpha1 and alpha2 collagen chains do not necessarily correspond.	Glycine	57-64	collagen type I alpha 2 chain	Homo sapiens	86-104
9135029-8	1997	The modeling studies find strong experimental support from mutagenesis studies on PKC alpha that reveal the crucial role played by the residues proline 11, leucine 20, leucine 24, and glycine 27.	Glycine	184-191	protein kinase C alpha	Homo sapiens	82-91
9111004-5	1997	Conversion of L12 of p38 to an "ERK-like" structure was accomplished in several ways: (i) by replacing glycine with glutamate in the dual phosphorylation site, (ii) by placing a six-amino acid sequence present in L12 of ERK (but absent in p38) into p38, and (iii) by mutations of amino acid residues in loop 12.	Glycine	103-110	mitogen-activated protein kinase 14	Homo sapiens	21-24
9111004-5	1997	Conversion of L12 of p38 to an "ERK-like" structure was accomplished in several ways: (i) by replacing glycine with glutamate in the dual phosphorylation site, (ii) by placing a six-amino acid sequence present in L12 of ERK (but absent in p38) into p38, and (iii) by mutations of amino acid residues in loop 12.	Glycine	103-110	mitogen-activated protein kinase 1	Homo sapiens	32-35
9151955-0	1997	The GLY1 gene of Saccharomyces cerevisiae encodes a low-specific L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine--expression of the gene in Escherichia coli and purification and characterization of the enzyme.	Glycine	149-156	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	4-8
9168138-7	1997	A protein encoded by the WS-3 gene has an R-G-D (Arg-Gly-Asp) motif in the N-terminal region, which seems to confer adhesive properties to macromolecular proteins like fibronectin.	Glycine	53-56	dynactin subunit 6	Homo sapiens	25-29
9168138-7	1997	A protein encoded by the WS-3 gene has an R-G-D (Arg-Gly-Asp) motif in the N-terminal region, which seems to confer adhesive properties to macromolecular proteins like fibronectin.	Glycine	53-56	fibronectin 1	Homo sapiens	168-179
9144530-5	1997	To study the significance of this Pro for the bioactivity and overall conformation of IL-2 it was mutated to Gly and Ala.	Glycine	109-112	interleukin 2	Homo sapiens	86-90
9151955-1	1997	The GLY1 gene of Saccharomyces cerevisiae is required for the biosynthesis of glycine for cell growth [McNeil, J.	Glycine	78-85	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	4-8
9151955-5	1997	We have found that the GLY1 protein is similar in primary structure to L-allo-threonine aldolase of Aeromonas jandiae DK-39, which stereospecifically catalyzes the interconversion of L-allo-threonine and glycine.	Glycine	204-211	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	23-27
9178034-2	1997	The weaver mutation is a Gly-to-Ser substitution in a conserved region of the Girk2 G protein-coupled inward rectifying potassium channel [Patil N., Cox D. R., Bhat D., Faham M., Myers R. M. and Peterson A. S. (1995) Nature Genet.	Glycine	25-28	potassium inwardly-rectifying channel, subfamily J, member 6	Mus musculus	78-83
9092503-6	1997	Proteolytic cleavage of pro-CCK occurred C-terminally of three basic sites; (i) Arg105-Arg106 which, upon exposure to carboxypeptidase activity, leads to the production of glycine-extended CCK; (ii) Arg95 to produce CCK-8 related processing intermediates; and (iii) Lys81 resulting in CCK-22 related products.	Glycine	172-179	cholecystokinin	Homo sapiens	28-31
9092503-6	1997	Proteolytic cleavage of pro-CCK occurred C-terminally of three basic sites; (i) Arg105-Arg106 which, upon exposure to carboxypeptidase activity, leads to the production of glycine-extended CCK; (ii) Arg95 to produce CCK-8 related processing intermediates; and (iii) Lys81 resulting in CCK-22 related products.	Glycine	172-179	cholecystokinin	Homo sapiens	189-192
9092503-6	1997	Proteolytic cleavage of pro-CCK occurred C-terminally of three basic sites; (i) Arg105-Arg106 which, upon exposure to carboxypeptidase activity, leads to the production of glycine-extended CCK; (ii) Arg95 to produce CCK-8 related processing intermediates; and (iii) Lys81 resulting in CCK-22 related products.	Glycine	172-179	cholecystokinin	Homo sapiens	189-192
9092503-6	1997	Proteolytic cleavage of pro-CCK occurred C-terminally of three basic sites; (i) Arg105-Arg106 which, upon exposure to carboxypeptidase activity, leads to the production of glycine-extended CCK; (ii) Arg95 to produce CCK-8 related processing intermediates; and (iii) Lys81 resulting in CCK-22 related products.	Glycine	172-179	cholecystokinin	Homo sapiens	189-192
9083028-7	1997	A CCK-BR mutant was further constructed by replacing five amino acids, Gly-Leu-Ser-Arg-(Arg)-Leu, in the first intracellular loop with the corresponding five CCK-AR specific amino acids, Ile-Arg-Asn-Lys-(Arg)-Met.	Glycine	71-74	cholecystokinin B receptor	Homo sapiens	2-8
9131005-4	1997	Two nucleotide substitutions accounted for all alpha chain abnormalities; one was conservative for Val333 and the other caused an Ala17--&gt;Gly substitution.	Glycine	141-144	Fc gamma receptor and transporter	Homo sapiens	47-58
9089084-5	1997	Although divergence is high, conservation among insect, vertebrate, and nematode Vg sequences is widespread with a preponderance of glycine, proline, and cysteine residues among strictly conserved amino acids, establishing conclusively that Vgs from the three phyla are homologous.	Glycine	132-139	putative uncharacterized protein LOC400499	Homo sapiens	81-83
9135136-2	1997	The location of the integrin binding sequence Arg-Gly-Asp (RGD) on human type 2 adenovirus (Ad2) was visualized by cryo-electron microscopy (cryo-EM) and image reconstruction using a mAb (DAV-1) which recognizes a linear epitope, IRGDTFATR.	Glycine	50-53	apolipoprotein E	Homo sapiens	92-95
9181551-9	1997	In conclusion, BSP mediated attachment of osteoblastic cells to hydroxyapatite, and this activity could be accomplished only by the poly-Glu sequence and the Arg-Gly-Asp sequence.	Glycine	162-165	integrin binding sialoprotein	Homo sapiens	15-18
9092716-7	1997	Again, Gly-Sar uptake mediated by the human PEPT 1 and PEPT 2 in HeLa cells was found to be inhibited by the anionic cephalosporins with the same order potency as in Caco-2 and SKPT cells.	Glycine	7-10	solute carrier family 15 member 1	Homo sapiens	44-50
9148753-5	1997	The N-terminal sequence of the two fragments generated by MMP-2 and MMP-3 is Leu211-Lys-Gly-Leu-Asn, but that of the others is Asp1-Glu-Ala-Ser-Gly.	Glycine	88-91	matrix metallopeptidase 3	Homo sapiens	68-73
9148753-5	1997	The N-terminal sequence of the two fragments generated by MMP-2 and MMP-3 is Leu211-Lys-Gly-Leu-Asn, but that of the others is Asp1-Glu-Ala-Ser-Gly.	Glycine	144-147	matrix metallopeptidase 3	Homo sapiens	68-73
9092716-7	1997	Again, Gly-Sar uptake mediated by the human PEPT 1 and PEPT 2 in HeLa cells was found to be inhibited by the anionic cephalosporins with the same order potency as in Caco-2 and SKPT cells.	Glycine	7-10	solute carrier family 15 member 2	Homo sapiens	55-61
9092716-9	1997	In this approach also it was found that PEPT 2-mediated Gly-Sar uptake was inhibited by cefixime and ceftibuten.	Glycine	56-59	solute carrier family 15 member 2	Homo sapiens	40-46
9056177-5	1997	A comparison with a data base suggested that the sequence is very similar to des-arg9bradykinin (arg-pro-pro-gly-phe-ser-pro-phe).	Glycine	109-112	kininogen 1	Homo sapiens	85-95
9045680-6	1997	In addition, the P1 carbonyl of the ketone inhibitor is pointing into the oxyanion hole and forms a hydrogen bond with the peptidic nitrogen of Gly-122, resulting in a different state compared with the tetrahedral intermediate observed in the structure of ICE and CPP32 in complex with an aldehyde inhibitor.	Glycine	144-147	caspase 1	Homo sapiens	256-259
9045680-6	1997	In addition, the P1 carbonyl of the ketone inhibitor is pointing into the oxyanion hole and forms a hydrogen bond with the peptidic nitrogen of Gly-122, resulting in a different state compared with the tetrahedral intermediate observed in the structure of ICE and CPP32 in complex with an aldehyde inhibitor.	Glycine	144-147	caspase 3	Homo sapiens	264-269
9065754-1	1997	We reported that a 33-amino-acid deletion (from tyrosine-715 to glycine-747) in a putative extracellular loop of GluR3 produced a mutant that exhibited dominant negative effects upon the functional expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors [Sekiguchi et al.	Glycine	64-71	glutamate receptor, ionotropic, AMPA 3 L homeolog	Xenopus laevis	113-118
9047300-1	1997	A 19-amino acid residue peptide, Gly-Trp-Leu-Lys-Ile-Lys-Ala-Ala-Met-Arg-Trp-Gly-Phe-Phe-Val-Arg-Lys-Lys- Ala, corresponding to the basic amphiphilic alpha-helix (BAA) motif at the C-terminus of a recombinant tobacco calmodulin-binding protein, TCB60, was synthesized.	Glycine	33-36	calmodulin	Nicotiana tabacum	217-227
9032114-8	1997	We have also identified the mutation in the HNF-1alpha gene in the Jutland pedigree, one of the original MODY pedigrees reported in the literature, as being a T--&gt;G substitution in codon 241, resulting in the replacement of a conserved Cys by Gly (C241G).	Glycine	246-249	HNF1 homeobox A	Homo sapiens	44-54
9073168-6	1997	In vitro expression studies have shown that the NR1-NR2C subunit combination exhibits weaker magnesium block and higher affinity for glycine than NR1-NR2B.	Glycine	133-140	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	Mus musculus	52-56
9115742-2	1997	The glycine binding site of these heteromeric receptor proteins is formed by regions of the NMDAR1 (NR1) subunit that display sequence similarity to bacterial amino acid binding proteins.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	92-98
9115742-2	1997	The glycine binding site of these heteromeric receptor proteins is formed by regions of the NMDAR1 (NR1) subunit that display sequence similarity to bacterial amino acid binding proteins.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	100-103
9115742-6	1997	Homology-based molecular modeling of the glutamate and glycine binding domains indicates that the NR2 and NR1 subunits use similar residues to ligate the agonists" alpha-aminocarboxylic acid groups, whereas differences in side chain interactions and size of aromatic residues determine ligand selectivity.	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	106-109
9147483-0	1997	Calretinin in the cat retina: colocalizations with other calcium-binding proteins, GABA and glycine.	Glycine	92-99	calbindin 2	Homo sapiens	0-10
9047300-1	1997	A 19-amino acid residue peptide, Gly-Trp-Leu-Lys-Ile-Lys-Ala-Ala-Met-Arg-Trp-Gly-Phe-Phe-Val-Arg-Lys-Lys- Ala, corresponding to the basic amphiphilic alpha-helix (BAA) motif at the C-terminus of a recombinant tobacco calmodulin-binding protein, TCB60, was synthesized.	Glycine	77-80	calmodulin	Nicotiana tabacum	217-227
9030612-1	1997	Previous studies have shown that fibrinogen can associate with endothelial cells via an Arg-Gly-Asp (RGD) recognition specificity.	Glycine	92-95	fibrinogen beta chain	Homo sapiens	33-43
9022054-2	1997	The single base substitution in Col2a1 resulted in a glycine to serine mutation within the helical domain and corresponded to one previously identified in a patient with the lethal human chondrodysplasia, hypochondrogenesis (Horton et al.	Glycine	53-60	collagen type II alpha 1 chain	Homo sapiens	32-38
9047339-1	1997	We have isolated the gene encoding the glycine cleavage T-protein (GCV1) of the yeast Saccharomyces cerevisiae and shown through gene disruption and enzyme assays that inactivation of GCV1 destroys glycine cleavage function.	Glycine	39-46	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	67-71
9047339-1	1997	We have isolated the gene encoding the glycine cleavage T-protein (GCV1) of the yeast Saccharomyces cerevisiae and shown through gene disruption and enzyme assays that inactivation of GCV1 destroys glycine cleavage function.	Glycine	39-46	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	184-188
9047339-1	1997	We have isolated the gene encoding the glycine cleavage T-protein (GCV1) of the yeast Saccharomyces cerevisiae and shown through gene disruption and enzyme assays that inactivation of GCV1 destroys glycine cleavage function.	Glycine	198-205	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	67-71
9047339-1	1997	We have isolated the gene encoding the glycine cleavage T-protein (GCV1) of the yeast Saccharomyces cerevisiae and shown through gene disruption and enzyme assays that inactivation of GCV1 destroys glycine cleavage function.	Glycine	198-205	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	184-188
9047339-3	1997	Growth with glycine stimulated expression of the GCV1 gene as determined by Northern analysis and increased the beta-galactosidase activity of a GCV1-lacZ fusion 30-fold.	Glycine	12-19	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	49-53
9047339-3	1997	Growth with glycine stimulated expression of the GCV1 gene as determined by Northern analysis and increased the beta-galactosidase activity of a GCV1-lacZ fusion 30-fold.	Glycine	12-19	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	145-149
9047339-6	1997	All gcv1 strains studied were unable to grow on glycine as a sole nitrogen source and lacked glycine cleavage enzyme activity.	Glycine	48-55	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	4-8
9047339-6	1997	All gcv1 strains studied were unable to grow on glycine as a sole nitrogen source and lacked glycine cleavage enzyme activity.	Glycine	93-100	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	4-8
9047339-7	1997	Growth of shm1 shm2 mutants was stimulated by glycine, whereas glycine could not supplement the growth of the isogenic gcv1 strain.	Glycine	46-53	glycine hydroxymethyltransferase SHM1	Saccharomyces cerevisiae S288C	10-19
9042048-5	1997	RESULTS: Analysis of TAP1 polymorphism in Tunisian patients with atopy and in unaffected control subjects demonstrates a high relative risk (RR) of atopy in carriers of a codon (d) corresponding to a glycine at position 637 of the TAP1-B and TAP1-D alleles.	Glycine	200-207	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	21-25
9042048-5	1997	RESULTS: Analysis of TAP1 polymorphism in Tunisian patients with atopy and in unaffected control subjects demonstrates a high relative risk (RR) of atopy in carriers of a codon (d) corresponding to a glycine at position 637 of the TAP1-B and TAP1-D alleles.	Glycine	200-207	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	231-235
9042048-5	1997	RESULTS: Analysis of TAP1 polymorphism in Tunisian patients with atopy and in unaffected control subjects demonstrates a high relative risk (RR) of atopy in carriers of a codon (d) corresponding to a glycine at position 637 of the TAP1-B and TAP1-D alleles.	Glycine	200-207	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	231-235
9042048-10	1997	Further evidence of the strong association between TAP1 polymorphism and atopy was provided by the finding that atopy is transmitted by inheritance of the glycine-637 marker.	Glycine	155-162	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	51-55
9042048-11	1997	CONCLUSIONS: Tunisian persons carrying the glycine-637 of the TAP1 protein may have an increased risk of atopy.	Glycine	43-50	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	62-66
18726304-2	1997	It was confirmed that the mt-p53 cDNA contained the complete coding sequence of p53 gene but mutated at codon 245 (G--&gt;T) and resulted in glycine to cysteine by sequencing analysis.	Glycine	141-148	tumor protein p53	Homo sapiens	29-32
9046591-3	1997	Glycine-rich repeats found in the carboxyl terminus of the endosperm-specific beta-amylase of barley and rye are absent from the maize gene product.	Glycine	0-7	beta-amylase	Zea mays	78-90
9230468-6	1997	The possibility of a beta-turn structure for the crucial Gly-Pro-Gly-Arg sequence has been confirmed by 2D NMR experiments.	Glycine	57-60	amyloid beta precursor protein	Homo sapiens	19-25
9012650-5	1997	As a model we used the two most basic regions of apoB-100, 3147 through 3157 and 3359 through 3367, connected by three glycines (3145-3157-GGG-3359-3367).	Glycine	119-127	apolipoprotein B	Homo sapiens	49-57
9174411-1	1997	MyristoylCoA: protein N-myristoyltransferase (NMT) catalyzes the cotranslational covalent attachment of a rare cellular fatty acid, myristate, to the N-terminal Gly residue of a variety of eukaryotic proteins.	Glycine	161-164	N-myristoyltransferase 1	Homo sapiens	46-49
9120775-9	1997	These studies suggest that the glycoprotein IIb/IIIa complex, present on activated-platelets, may interact with fibronectin and vitronectin substrates through the Arg-Gly-Asp-dependent mechanism.	Glycine	167-170	fibronectin 1	Homo sapiens	112-123
8999850-10	1997	Surprisingly, these proteins did not bind to the domains involved in transactivation, but rather to the zinc finger and Gly/Ala-rich domains of YY1.	Glycine	120-123	YY1 transcription factor	Homo sapiens	144-147
9493968-5	1997	The cleavage occurs between Asp-214 and Gly-215, a site that is conserved in human, bovine, and chicken PARP.	Glycine	40-43	poly(ADP-ribose) polymerase 1	Homo sapiens	104-108
9155591-4	1997	RESULTS: The histopathological damage in the liver, and the concanavalin A induced release of TNF alpha and IL6 were significantly inhibited by the synthetic Arg-Gly-Asp mimetic (p &lt; 0.001).	Glycine	162-165	tumor necrosis factor	Mus musculus	94-103
9155591-4	1997	RESULTS: The histopathological damage in the liver, and the concanavalin A induced release of TNF alpha and IL6 were significantly inhibited by the synthetic Arg-Gly-Asp mimetic (p &lt; 0.001).	Glycine	162-165	interleukin 6	Mus musculus	108-111
9230468-6	1997	The possibility of a beta-turn structure for the crucial Gly-Pro-Gly-Arg sequence has been confirmed by 2D NMR experiments.	Glycine	65-68	amyloid beta precursor protein	Homo sapiens	19-25
9145433-2	1997	This chimeric calcitonin precursor terminates at glycine to easily receive an amidation reaction.	Glycine	49-56	calcitonin related polypeptide alpha	Homo sapiens	14-24
8943258-6	1996	Bax proteins expressing alanine substitutions of the highly conserved amino acids glycine 108 (G108) in BH1, tryptophan 158 (W158) in BH2, and glycine 67 and aspartic acid 68 (GD67-68) in BH3 as well as deletion of the most conserved amino acids in BH1 (Delta102-112) and BH2 (Delta151-159) and deletion of BH3 (Delta63-71) maintained their ability to accelerate chemotherapy-induced cell death.	Glycine	82-89	BCL2 associated X, apoptosis regulator	Homo sapiens	0-3
9437709-5	1997	Python neurokinin A (His-Lys-Thr-Asp-Ser-Phe-Val-Gly- Leu-Met.NH2) is identical to human/chicken/alligator neurokinin A.	Glycine	49-52	tachykinin precursor 1	Homo sapiens	7-19
9606729-1	1997	NMR spectroscopy has been used to obtain structural information on the bioactive conformation of the nonapeptide hormone bradykinin (Arg-Pro-Pro-Gly-Ser-Pro-Phe-Arg, BK) bound to the Fab-fragment of an antibody that mimics the hormone binding site of the natural bradykinin B2-receptor.	Glycine	145-148	kininogen 1	Homo sapiens	121-131
8943295-0	1996	The effects of amino acid replacements of glycine 121 on transmembrane helix 3 of rhodopsin.	Glycine	42-49	rhodopsin	Homo sapiens	82-91
8958208-6	1996	We also tested the ability of IGFBP-2, a related binding protein which has an arginine-glycine-aspartate sequence but does not associate with integrin family members, to enhance IGF-I bioactivity.	Glycine	87-94	insulin-like growth factor-binding protein 2	Oryctolagus cuniculus	30-37
8943276-4	1996	A growth hormone antagonist mutant Gly-120 --&gt; Arg, has been crystallized with its receptor as a 1:1 complex and the crystal structure determined at 2.9 A resolution.	Glycine	35-38	growth hormone 1	Homo sapiens	2-16
8945538-5	1996	The m68 (Lys-13--&gt;Glu and Arg-22--&gt;Gly) variant is significantly less potent than the recombinant histatin-5 as well as m71, indicating that Arg-22 is crucial for the cidal activity.	Glycine	41-44	TNF receptor superfamily member 6b	Homo sapiens	4-7
8945538-5	1996	The m68 (Lys-13--&gt;Glu and Arg-22--&gt;Gly) variant is significantly less potent than the recombinant histatin-5 as well as m71, indicating that Arg-22 is crucial for the cidal activity.	Glycine	41-44	histatin 3	Homo sapiens	104-114
8947046-4	1996	TGF-beta1 induced in vivo phosphorylation of serine and threonine residues in the juxtamembrane domain of TbetaR-I in a region rich in glycine, serine and threonine residues (GS domain; Thr185, Thr186, Ser187, Ser189 and Ser191), and more N-terminal of this region (Ser165).	Glycine	135-142	transforming growth factor beta 1	Homo sapiens	0-9
8967993-9	1996	At saturating concentrations of NMDA (1 mM), NR1-1a/2A heteromers also showed Ca- and glycine-independent desensitization, as seen in native hippocampal neurons.	Glycine	86-93	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	45-48
8967993-10	1996	Ca(2+)- and glycine-independent desensitization was less pronounced in NR1-1a/2B heteromers and absent in NR1-1a/2C heteromers.	Glycine	12-19	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	71-74
8917507-5	1996	Association between YY1 and mammalian RPD3 requires a glycine-rich region on YY1.	Glycine	54-61	YY1 transcription factor	Homo sapiens	20-23
8917507-5	1996	Association between YY1 and mammalian RPD3 requires a glycine-rich region on YY1.	Glycine	54-61	histone deacetylase 2	Homo sapiens	38-42
8917507-5	1996	Association between YY1 and mammalian RPD3 requires a glycine-rich region on YY1.	Glycine	54-61	YY1 transcription factor	Homo sapiens	77-80
8922600-1	1996	A synthetic peptide, Gly-Arg-Gly-Asp-Ser-Pro-Lys (GRGDSPK), which includes the cell-adhesive region of fibronectin, Arg-Gly-Asp (RGD), was covalently bound to a dialdehyde starch (DAS) coating on a polymer surface by reductive amination.	Glycine	21-24	fibronectin 1	Homo sapiens	103-114
8916896-11	1996	Collectively, computer modeling of the wild-type and mutant forms of the ALAS glycine loop and biochemical and spectroscopic characterization of G144A, G144S, G144T, and G142C strongly suggest that the conserved glycine loop in 5-aminolevulinate synthase is a pyridoxal 5"-phosphate cofactor binding motif.	Glycine	78-85	5'-aminolevulinate synthase 1	Homo sapiens	73-77
8916896-11	1996	Collectively, computer modeling of the wild-type and mutant forms of the ALAS glycine loop and biochemical and spectroscopic characterization of G144A, G144S, G144T, and G142C strongly suggest that the conserved glycine loop in 5-aminolevulinate synthase is a pyridoxal 5"-phosphate cofactor binding motif.	Glycine	212-219	5'-aminolevulinate synthase 1	Homo sapiens	73-77
8893840-2	1996	A new mode of binding of ACh to AChE was found which involves the carboxyl oxygen of ACh interacting with Gly 118 and 119.	Glycine	106-109	acetylcholinesterase (Cartwright blood group)	Homo sapiens	32-36
8885940-0	1996	The effect of intracervical vasopressin on the systemic absorption of glycine during hysteroscopic endometrial ablation.	Glycine	70-77	arginine vasopressin	Homo sapiens	28-39
8953651-9	1996	Glu-21 and Gly-75, but not Gln-86, are structurally equivalent to residues involved in the growth hormone binding to its receptor.	Glycine	11-14	growth hormone 1	Homo sapiens	91-105
8863813-0	1996	Activation of N-methyl-D-aspartate receptors by glycine: role of an aspartate residue in the M3-M4 loop of the NR1 subunit.	Glycine	48-55	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	111-114
8917094-5	1996	In the transcriptional regulatory region, however, three domains, a glycine stretch, a proline stretch and one alternative splice site which are present in the mammalian WT1, are not conserved in amphibians.	Glycine	68-75	WT1 transcription factor	Homo sapiens	170-173
8813154-5	1996	Overexpression of FN also suppressed the ability of the tumor cells to proliferate in soft agar, whereas the suppression was reversed by inclusion in soft agar of the Arg-Gly-Asp (RGD)-containing peptide and adhesion-blocking antibodies against the central cell-binding domain of FN.	Glycine	171-174	fibronectin 1	Homo sapiens	18-20
8863813-8	1996	Residue D732 in NR1 may be close to a glycine binding site on the NMDA receptor and may directly affect the properties of this site or be critical for coupling of glycine binding to channel activation.	Glycine	38-45	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	16-19
8863813-8	1996	Residue D732 in NR1 may be close to a glycine binding site on the NMDA receptor and may directly affect the properties of this site or be critical for coupling of glycine binding to channel activation.	Glycine	163-170	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	16-19
8863813-3	1996	Mutations at NR1(D732) also changed sensitivity to the glycine-site agonists D-serine and D-alanine, reducing the potencies and, in some cases, the efficacies of these compounds.	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	13-16
8863813-4	1996	Thus, D-serine was a full agonist at the glycine site of receptors containing NR1(D732N) and NR1(D732A), a partial agonist at receptors containing NR1(D732G), and a competitive antagonist at receptors containing NR1(D732).	Glycine	41-48	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	78-81
8863813-4	1996	Thus, D-serine was a full agonist at the glycine site of receptors containing NR1(D732N) and NR1(D732A), a partial agonist at receptors containing NR1(D732G), and a competitive antagonist at receptors containing NR1(D732).	Glycine	41-48	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	93-96
8863813-4	1996	Thus, D-serine was a full agonist at the glycine site of receptors containing NR1(D732N) and NR1(D732A), a partial agonist at receptors containing NR1(D732G), and a competitive antagonist at receptors containing NR1(D732).	Glycine	41-48	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	93-96
8863813-4	1996	Thus, D-serine was a full agonist at the glycine site of receptors containing NR1(D732N) and NR1(D732A), a partial agonist at receptors containing NR1(D732G), and a competitive antagonist at receptors containing NR1(D732).	Glycine	41-48	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	93-96
8863813-5	1996	Mutations at NR1(D732) had no effect or produced an increase in sensitivity to the glycine-site antagonists 6,7-dichloroquinoxaline-2,3-dione and 5,7-dichlorokynurenic acid.	Glycine	83-90	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	13-16
8798665-4	1996	The BH1 sequence in 19K is degenerate but nevertheless contains a conserved glycine residue found in all family members that when mutated to alanine in Bcl-2 results in loss of Bcl-2 function and ability to dimerize with Bax (Yin, X.-M., Oltvai, Z. N., and Korsmeyer, S. J.	Glycine	76-83	BCL2 apoptosis regulator	Homo sapiens	152-157
8871553-3	1996	In addition to the conserved core domains characteristic of DEAD box proteins, p72 contains several N-terminal RGG RNA-binding domains and a serine/glycine rich C-terminus likely involved in mediating protein-protein interactions.	Glycine	148-155	DEAD-box helicase 17	Homo sapiens	79-82
8798665-4	1996	The BH1 sequence in 19K is degenerate but nevertheless contains a conserved glycine residue found in all family members that when mutated to alanine in Bcl-2 results in loss of Bcl-2 function and ability to dimerize with Bax (Yin, X.-M., Oltvai, Z. N., and Korsmeyer, S. J.	Glycine	76-83	BCL2 apoptosis regulator	Homo sapiens	177-182
8798665-4	1996	The BH1 sequence in 19K is degenerate but nevertheless contains a conserved glycine residue found in all family members that when mutated to alanine in Bcl-2 results in loss of Bcl-2 function and ability to dimerize with Bax (Yin, X.-M., Oltvai, Z. N., and Korsmeyer, S. J.	Glycine	76-83	BCL2 associated X, apoptosis regulator	Homo sapiens	221-224
8823380-4	1996	Patients with remitting/relapsing MS also had elevated autoantibody to a lymphocyte protein, p542, cross reactive with EBNA-1 through a glycine/serine epitope.	Glycine	136-143	RALY heterogeneous nuclear ribonucleoprotein	Homo sapiens	93-97
8787673-4	1996	Subsequently, a glycine to glutamic acid substitution was identified in the collagenous region of the COL4A4 gene.	Glycine	16-23	collagen type IV alpha 4 chain	Homo sapiens	102-108
8703082-3	1996	Alanine, glycine, and proline repeats were present in the mammalian Brain-1 gene, whereas most of these repeats were absent in the nonmammalian homologue.	Glycine	9-16	POU class 3 homeobox 3	Homo sapiens	68-75
8703082-4	1996	The mammalian Brain-2 gene had alanine, glycine, proline, and glutamine repeats, which were missing in the nonmammalian homologue.	Glycine	40-47	POU class 3 homeobox 2	Homo sapiens	14-21
8798452-6	1996	Bax proteins expressing alanine substitutions of the highly conserved amino acids glycine 108 in BH1, tryptophan 151 and 158 in BH2, and glycine 67 and aspartic acid 68 in BH3 retained their ability to promote chemotherapy-induced cell death that was inhibited by Bcl-XL and to form heterodimers with Bcl-XL.	Glycine	82-89	BCL2 associated X, apoptosis regulator	Homo sapiens	0-3
8798452-6	1996	Bax proteins expressing alanine substitutions of the highly conserved amino acids glycine 108 in BH1, tryptophan 151 and 158 in BH2, and glycine 67 and aspartic acid 68 in BH3 retained their ability to promote chemotherapy-induced cell death that was inhibited by Bcl-XL and to form heterodimers with Bcl-XL.	Glycine	137-144	BCL2 associated X, apoptosis regulator	Homo sapiens	0-3
8769411-11	1996	Furthermore, through the use of the two-hybrid system, it was demonstrated that both the PAS10 gene product (Pas10p) and the human PTS1 receptor can interact with the COOH-terminal region of human catalase, but that this interaction is abolished by substitutions at the penultimate residue (asparagine-to- aspartate) and at the fourth residue from the COOH terminus (lysine-to-glycine) which abolish PTS functionality.	Glycine	377-384	catalase	Homo sapiens	197-205
8707840-5	1996	We found that p58 contains regions with FG (Phe, Gly) and PA (Pro, Ala) repeats at both its NH2 and COOH termini separated by a predicted alpha-helical coiled-coil region, while p54 has an NH2-terminal FG and PA repeat region and a COOH-terminal predicted coiled-coil region.	Glycine	49-52	DNA primase subunit 2	Rattus norvegicus	14-17
8905849-1	1996	A large family affected with autosomal dominant retinitis pigmentosa (ADRP) with a sectorial phenotype showed a previously described (G to A) mutation in the rhodopsin gene resulting in the substitution of a glycine residue by an arginine in codon 106 of rhodopsin.	Glycine	208-215	rhodopsin	Homo sapiens	158-167
8905849-1	1996	A large family affected with autosomal dominant retinitis pigmentosa (ADRP) with a sectorial phenotype showed a previously described (G to A) mutation in the rhodopsin gene resulting in the substitution of a glycine residue by an arginine in codon 106 of rhodopsin.	Glycine	208-215	rhodopsin	Homo sapiens	255-264
8702713-6	1996	Mutation of Ala-408 to Glu or Arg-413 to Gly led to a complete loss of enzyme activity despite expression of mutant protein levels equivalent to that of the wild-type TXAS.	Glycine	41-44	thromboxane A synthase 1	Homo sapiens	167-171
8709147-8	1996	While Blk and Lyn had a strong preference for a negatively charged amino acid in position +1, c-Src preferred tryptophan or glycine in this position.	Glycine	124-131	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	94-99
8899663-2	1996	Glutamate (GLU), kainate and AMPA, as well as glycine (GLY) evoked dose-related, calcium-dependent liberation of soluble forms of AChE from both slices and synaptosomes.	Glycine	46-53	acetylcholinesterase (Cartwright blood group)	Homo sapiens	130-134
8899663-0	1996	Glycine effects on glutamate-receptor elicited acetylcholinesterase release from slices and synaptosomes of the spinal ventral horn.	Glycine	0-7	acetylcholinesterase (Cartwright blood group)	Homo sapiens	47-67
8899663-2	1996	Glutamate (GLU), kainate and AMPA, as well as glycine (GLY) evoked dose-related, calcium-dependent liberation of soluble forms of AChE from both slices and synaptosomes.	Glycine	55-58	acetylcholinesterase (Cartwright blood group)	Homo sapiens	130-134
8899663-3	1996	GLY-evoked AChE release showed remarkable age-related postnatal changes.	Glycine	0-3	acetylcholinesterase (Cartwright blood group)	Homo sapiens	11-15
8899663-5	1996	GLY potentiated the GEAR response in the presence of strychnine, suggesting N-methyl-D-aspartate (NMDA) receptor involvement, and was also able to evoke a strychnine-sensitive AChE release in the absence of exogenous GLU.	Glycine	0-3	acetylcholinesterase (Cartwright blood group)	Homo sapiens	176-180
8899663-6	1996	After the 28th postnatal day, nearly all the AChE secreted was released either after the activation of non-NMDA glutamate receptors or by strychnine-sensitive GLY-evoked AChE release mechanisms.	Glycine	159-162	acetylcholinesterase (Cartwright blood group)	Homo sapiens	45-49
8899663-6	1996	After the 28th postnatal day, nearly all the AChE secreted was released either after the activation of non-NMDA glutamate receptors or by strychnine-sensitive GLY-evoked AChE release mechanisms.	Glycine	159-162	acetylcholinesterase (Cartwright blood group)	Homo sapiens	170-174
8899663-7	1996	Both GEAR and GLY-evoked AChE release might impair the negative feedback loop which modulates the overactivation of motor neurones, and cause prolonged extracellular rises of soluble AChE.	Glycine	14-17	acetylcholinesterase (Cartwright blood group)	Homo sapiens	25-29
8899663-7	1996	Both GEAR and GLY-evoked AChE release might impair the negative feedback loop which modulates the overactivation of motor neurones, and cause prolonged extracellular rises of soluble AChE.	Glycine	14-17	acetylcholinesterase (Cartwright blood group)	Homo sapiens	183-187
8691458-9	1996	Replacement of Gly by Ala in these mercaptoacyl dipeptides induced an about 100-fold decrease in ACE inhibition.	Glycine	15-18	angiotensin I converting enzyme	Rattus norvegicus	97-100
8755812-10	1996	The reperfusion-induced increase in MPO activity was abolished in intestinal segments flushed with glycine.	Glycine	99-106	myeloperoxidase	Canis lupus familiaris	36-39
8755736-8	1996	For ACE-JMLDL, in which the native cleavage site is absent, observed masses of 4372 and 4542 are in close agreement with expected masses of 4371 and 4542 for peptides ending at Ala-628 and Gly-630, respectively, indicating cleavages at 17 or 15 residues from the membrane.	Glycine	189-192	angiotensin-converting enzyme	Cricetulus griseus	4-7
8692995-3	1996	Because native SP requires a C-terminal amide moiety to bind with high affinity to the SP receptor, the precursor form of the fusion toxin, DAB389SP-Gly, was converted to DAB389SP by treatment with peptidylglycine-alpha-amidating monooxygenase.	Glycine	149-152	tachykinin precursor 1	Homo sapiens	15-17
8692995-3	1996	Because native SP requires a C-terminal amide moiety to bind with high affinity to the SP receptor, the precursor form of the fusion toxin, DAB389SP-Gly, was converted to DAB389SP by treatment with peptidylglycine-alpha-amidating monooxygenase.	Glycine	149-152	tachykinin precursor 1	Homo sapiens	87-89
8660692-0	1996	Active-site topologies of human CYP2D6 and its aspartate-301 --&gt; glutamate, asparagine, and glycine mutants.	Glycine	95-102	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	32-38
8765746-3	1996	The deduced product of the Xenopus Sox gene (xSox-11) consisted of the standard domains of an HMG box, glycine/alanine-rich region and glutamic acid/aspartic acid-rich region and may be involved in the control of transcription.	Glycine	103-110	SRY-box 3 L homeolog	Xenopus laevis	45-52
8806482-3	1996	The amino acid sequences of EBNA1 of HVP and EBV are 56% identical, if the difference in the length of the glycine and alanine containing repetitive region, which is much shorter for HVP EBNA1, is omitted for the calculation.	Glycine	107-114	EBNA-1	Human gammaherpesvirus 4	28-33
8843097-2	1996	The specific mu-receptor opioid agonist, Tyr, D-Ala2, Gly, N-Me-Phe4, Gly-ol5 (DAMGO), was found to increase AP-1 and NF-kappa B activity in primary cultures of neurons from rat cerebral cortex.	Glycine	54-57	nuclear factor kappa B subunit 1	Homo sapiens	118-128
8688416-5	1996	15N-Labeled glycine residues in S100b showed calcium-induced chemical shift changes similar to those reported for the related monomeric protein calbindin D9k, suggesting similar conformational changes are occurring in the calcium-binding loops of these two proteins.	Glycine	12-19	S100 calcium binding protein B	Homo sapiens	32-37
8663190-1	1996	Membrane-bound dipeptidase (MBD) participates in the degradation of glutathione by cleaving the cysteinyl-glycine bond of cystinyl bisglycine (oxidized cysteinyl-glycine) following removal of a gamma-glutamyl group by gamma-glutamyl transpeptidase (GGT).	Glycine	106-113	gamma-glutamyltransferase 1	Mus musculus	218-247
8663190-1	1996	Membrane-bound dipeptidase (MBD) participates in the degradation of glutathione by cleaving the cysteinyl-glycine bond of cystinyl bisglycine (oxidized cysteinyl-glycine) following removal of a gamma-glutamyl group by gamma-glutamyl transpeptidase (GGT).	Glycine	106-113	gamma-glutamyltransferase 1	Mus musculus	249-252
8760112-3	1996	The elevation in serum tumor necrosis factor-alpha (TNF-alpha) due to LPS was also blunted and delayed significantly by glycine feeding.	Glycine	120-127	tumor necrosis factor	Rattus norvegicus	23-50
8760112-3	1996	The elevation in serum tumor necrosis factor-alpha (TNF-alpha) due to LPS was also blunted and delayed significantly by glycine feeding.	Glycine	120-127	tumor necrosis factor	Rattus norvegicus	52-61
8663002-1	1996	Fibronectin has been shown to bind to integrin alphaIIbbeta3 in Arg-Gly-Asp (RGD)-dependent and -independent manners.	Glycine	68-71	fibronectin 1	Homo sapiens	0-11
8662767-12	1996	L-Methionine, L-leucine, L-glycine, and L-valine were also transported by ASCT2 but with lower affinity.	Glycine	25-34	solute carrier family 1 (neutral amino acid transporter), member 5	Mus musculus	74-79
8660661-2	1996	Rapid quantitative assays have been used to study the effect of mutating BiP residue 229, located in the ATP binding site, from threonine to glycine.	Glycine	141-148	heat shock protein family A (Hsp70) member 5	Homo sapiens	73-76
8650214-0	1996	The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	32-73
8662907-9	1996	Mutational analysis revealed that glycine at position +1 of ST12 inhibited the binding to Grb2 while retaining the high affinity binding to CRK SH3.	Glycine	34-41	growth factor receptor bound protein 2	Homo sapiens	90-94
8662907-9	1996	Mutational analysis revealed that glycine at position +1 of ST12 inhibited the binding to Grb2 while retaining the high affinity binding to CRK SH3.	Glycine	34-41	CRK proto-oncogene, adaptor protein	Homo sapiens	140-143
8650214-2	1996	Here, the contribution of the M3-M4 loop of the NR1 subunit to the binding of glutamate and the co-agonist glycine was investigated by site-directed mutagenesis.	Glycine	107-114	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	48-51
8650214-6	1996	These results indicate that the M3-M4 loop is part of the ligand-binding pocket of the NR1 subunit and provide the basis for a refined model of the glycine-binding site of the NMDA receptor.	Glycine	148-155	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	87-90
8669466-3	1996	In this study, we report a patient with a form of junctional epidermolysis bullosa with skin fragility and dental anomalies who is a compound heterozygote for a novel combination of mutations, ie, a glycine substitution mutation in one allele and an internal duplication in the other allele of COL17A1.	Glycine	199-206	collagen type XVII alpha 1 chain	Homo sapiens	294-301
8632186-3	1996	The polyamine site agonist spermine showed differential modulation of glutamate- and glycine-stimulated 45Ca2+ influx for recombinant NMDA receptors, inhibiting and stimulating 45Ca2+ influx into cells expressing NR1a/NR2A receptors (IC50 = 408 microM) and NR1a/NR2B receptors (EC50 = 37.3 microM), respectively.	Glycine	85-92	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	218-222
8824571-5	1996	Amino acid usage in the CDR3 region is nonrandom with a predominance of charged or polar residues in the TCRA transcript and a majority of glycines in TCRB.	Glycine	139-147	T cell receptor beta locus	Homo sapiens	151-155
8649684-8	1996	RESULTS: Plasma glycine maximal concentrations were significantly lower (P &lt; .001) in patients who received vasopressin, compared with controls (8.8 +/- 4.5 versus 16.0 +/- 6.3 mmol/L, respectively).	Glycine	16-23	arginine vasopressin	Homo sapiens	111-122
8817456-2	1996	The serine residue, which is essential for enzymatic activity, has been substituted by glycine, suggesting that MAS could serve to antagonize serine protease activity [Murugasu-Oei et al.	Glycine	87-94	masquerade	Drosophila melanogaster	112-115
8649684-0	1996	The effect of intracervical vasopressin on the systemic absorption of glycine during hysteroscopic endometrial ablation.	Glycine	70-77	arginine vasopressin	Homo sapiens	28-39
8649684-1	1996	OBJECTIVE: To examine the effect of paracervical injection of vasopressin on the absorption of glycine during transcervical endometrial ablation.	Glycine	95-102	arginine vasopressin	Homo sapiens	62-73
8649684-11	1996	CONCLUSION: Intracervical vasopressin administration significantly decreased systemic glycine absorption in patients undergoing hysteroscopic endometrial ablation.	Glycine	86-93	arginine vasopressin	Homo sapiens	26-37
8733574-12	1996	The binding site for the two phenol derivatives onto ICln seems to be distinct but closely related to the nucleotide binding site identified as G x G x G, a glycine repeat located at the predicted outer mouth of the ICln channel protein.	Glycine	157-164	methylosome subunit pICln	Canis lupus familiaris	53-57
8694526-6	1996	In this study an increased [Gly]/[Cr + PCr] ratio was observed in GM with respect to AII and AA.	Glycine	28-31	NLR family pyrin domain containing 3	Homo sapiens	85-88
8611724-7	1996	In particular, the chimpanzee RBCs cells expressed Wrb and the Glu658 form of band 3, which is identical to humans, but their GPA contained the Gly rather than Arg residue at position 61.	Glycine	144-147	glycophorin A (MNS blood group)	Homo sapiens	126-129
8733574-12	1996	The binding site for the two phenol derivatives onto ICln seems to be distinct but closely related to the nucleotide binding site identified as G x G x G, a glycine repeat located at the predicted outer mouth of the ICln channel protein.	Glycine	157-164	methylosome subunit pICln	Canis lupus familiaris	216-220
8673107-3	1996	Sequencing of the loricrin gene revealed an insertion that shifts the translation frame of the C-terminal Gly- and Gln/Lys-rich domains, and is likely to impair cornification.	Glycine	106-109	loricrin cornified envelope precursor protein	Homo sapiens	18-26
8613982-8	1996	The S1 pocket of t-PA is almost identical to that of trypsin, whereas the S2 site is considerably reduced in size by the imposing Tyr368 side-chain, in agreement with the measured preference for P1 Arg and P2 Gly residues.	Glycine	209-212	plasminogen activator, tissue type	Homo sapiens	17-21
8612578-5	1996	Site-directed mutagenesis of residues K72 and Y73 within the glycine-rich motif followed by the expression of the KBP mutants at the surface of HEK 293 cells showed a decrease in GTP binding affinity by factors of 10 and 100 respectively.	Glycine	61-68	kinesin family binding protein	Homo sapiens	114-117
8628291-0	1996	A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit.	Glycine	2-9	nuclear factor kappa B subunit 1	Homo sapiens	35-39
8628291-0	1996	A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit.	Glycine	2-9	nuclear factor kappa B subunit 1	Homo sapiens	99-102
8628291-4	1996	We report here that a 23-amino-acid, glycine-rich region (GRR) in p105 functions as a processing signal for the generation of p50.	Glycine	37-44	nuclear factor kappa B subunit 1	Homo sapiens	66-70
8628291-4	1996	We report here that a 23-amino-acid, glycine-rich region (GRR) in p105 functions as a processing signal for the generation of p50.	Glycine	37-44	nuclear factor kappa B subunit 1	Homo sapiens	126-129
8612578-7	1996	Accordingly, we propose that the glycine-rich motif of KBP forms part of a guanine nucleotide binding site.	Glycine	33-40	kinesin family binding protein	Homo sapiens	55-58
8605964-14	1996	Further, the omission of Epo caused an 80% decrease in the number of BFU-E and a corresponding 94% decrease in the number of CD71++gly A- cells, thereby maintaining the relationship between CD71++gly A- cells and BFU-E.	Glycine	131-134	erythropoietin	Homo sapiens	25-28
9133666-7	1996	Overexpression of MLE or its carboxyl terminus, which includes glycine-rich repeats, reveals an RNase-sensitive affinity for all chromosome arms.	Glycine	63-70	maleless	Drosophila melanogaster	18-21
8740448-0	1996	Ca2+ and H+ antagonize the decrease of [3H]MK-801 binding induced by glutamate and glycine in the presence of Mg2+.	Glycine	83-90	carbonic anhydrase 2	Rattus norvegicus	0-3
8740448-6	1996	In contrast, Ca2+ and H+ antagonized these glutamate- and glycine-induced decreases of [3H]MK-801 binding observed in the presence of Mg2+, possibly by a direct competitive action on the permissive Mg2+ effect.	Glycine	58-65	carbonic anhydrase 2	Rattus norvegicus	13-16
8636086-2	1996	Analogous binding specificity can be engineered into the homologous rat mannose-binding protein A by changing three amino acids and inserting a glycine-rich loop (Iobst, S. T., and Drickamer, K. (1994) J. Biol.	Glycine	144-151	mannose binding lectin 1	Rattus norvegicus	72-97
8652624-2	1996	Insertion of histidine and glycine at positions 77 and 78 in bovine MBP greatly reduces the encephalitogenicity of the protein.	Glycine	27-34	myelin basic protein	Bos taurus	68-71
8636133-5	1996	The primary structure of cGK II is devoid of hydrophobic transmembrane domains; cGK II does, however, contain a penultimate glycine, a potential acceptor for a myristoyl moiety.	Glycine	124-131	protein kinase cGMP-dependent 2	Homo sapiens	25-31
8636133-5	1996	The primary structure of cGK II is devoid of hydrophobic transmembrane domains; cGK II does, however, contain a penultimate glycine, a potential acceptor for a myristoyl moiety.	Glycine	124-131	protein kinase cGMP-dependent 2	Homo sapiens	80-86
8648190-7	1996	Adhesion to fibronectin and vitronectin was found to be divalent cation- and arginine-glycine-aspartic acid-dependent, and could be blocked by antibodies to beta 1 or alpha 5, and alpha v or alpha v beta 5, respectively.	Glycine	86-93	fibronectin 1	Homo sapiens	12-23
8617744-7	1996	Alteration of a Leu at position -5 (with respect to Tyr(P)) in the EGFR peptide to Gly also reduced the binding affinity (KD = 580 nM).	Glycine	83-86	epidermal growth factor receptor	Homo sapiens	67-71
8740695-1	1996	One family (ADRP15) was found to have mutation in codon 114 of the rhodopsin gene that led to a substitution of a glycine for an aspartic acid.	Glycine	114-121	rhodopsin	Homo sapiens	67-76
8728690-10	1996	The proband is the first reported case of OI with a glycine substitution by alanine in the pro alpha 2(I) chain of type I procollagen.	Glycine	52-59	collagen type I alpha 2 chain	Homo sapiens	115-133
8868493-2	1996	Interestingly, the beta s values of both DHFR and AspAT were influenced markedly by the mutations at glycine-121 and valine-39, respectively, in which the magnitude of the change was proportional to the enzyme activity.	Glycine	101-108	dihydrofolate reductase	Escherichia coli	41-45
8867898-4	1996	Expression in Escherichia coli led to secretion in the periplasmic space of a fully bioactive hPRL variant constituting authentic hPRL with a peptide tag, i.e. Ala-Ser-(His)6-Ile-Glu-Gly-Arg, at its N-terminal.	Glycine	183-186	prolactin	Homo sapiens	94-98
8932515-8	1996	The glycine transport was inhibited by a number of other amino acids which are known to be transported through the A and ASC systems.	Glycine	4-11	PYD and CARD domain containing	Homo sapiens	121-124
8932515-9	1996	The glycine transport system may be dependent on multiple pathways such as the A, ASC or Gly which is a variant of pathway A. Glycine transport was inhibited by ouabain, a known Na+/K+ -ATPase inhibitor, in the BCM vesicles but not in the BBM system.	Glycine	4-11	PYD and CARD domain containing	Homo sapiens	82-85
8714523-0	1996	Glycine increases the number of somatostatin receptors and somatostatin-mediated inhibition of the adenylate cyclase system in the rat hippocampus.	Glycine	0-7	somatostatin	Rattus norvegicus	32-44
8852837-6	1996	With the inactivation of SHM1, however, the glycine cleavage system can make an observable contribution to the level of mitochondrial formate.	Glycine	44-51	glycine hydroxymethyltransferase SHM1	Saccharomyces cerevisiae S288C	25-29
8598221-1	1996	The hematopoietic cell recognition sites of human fibronectin (FN) are the Arg-Gly-Asp-Ser (RGDS) sequence recognized by widely distributed integrin receptor alpha 5 beta 1 and the type III connecting segment (III CS) containing two cell-binding sites, designated CS1 and CS5, that are recognized by the alpha 4 beta 1 receptor.	Glycine	79-82	fibronectin 1	Homo sapiens	50-61
8598221-1	1996	The hematopoietic cell recognition sites of human fibronectin (FN) are the Arg-Gly-Asp-Ser (RGDS) sequence recognized by widely distributed integrin receptor alpha 5 beta 1 and the type III connecting segment (III CS) containing two cell-binding sites, designated CS1 and CS5, that are recognized by the alpha 4 beta 1 receptor.	Glycine	79-82	fibronectin 1	Homo sapiens	63-65
8714523-0	1996	Glycine increases the number of somatostatin receptors and somatostatin-mediated inhibition of the adenylate cyclase system in the rat hippocampus.	Glycine	0-7	somatostatin	Rattus norvegicus	59-71
8789947-1	1996	The weaver mutation corresponds to a substitution of glycine to serine in the H5 region of a G protein-gated inwardly rectifying K+ channel gene (GIRK2).	Glycine	53-60	potassium inwardly-rectifying channel, subfamily J, member 6	Mus musculus	146-151
9005443-6	1996	Kinetic analysis of thrombin inhibition revealed that most of the chimeras tested competitively inhibit the thrombin-mediated cleavage of a peptide substrate in a concentration-dependent manner; however, in two examples the insertion of one glycine residue into the active site directed-sequence abolished the blockade of the active site.	Glycine	241-248	coagulation factor II, thrombin	Homo sapiens	20-28
9005443-6	1996	Kinetic analysis of thrombin inhibition revealed that most of the chimeras tested competitively inhibit the thrombin-mediated cleavage of a peptide substrate in a concentration-dependent manner; however, in two examples the insertion of one glycine residue into the active site directed-sequence abolished the blockade of the active site.	Glycine	241-248	coagulation factor II, thrombin	Homo sapiens	108-116
9244172-2	1996	Mitochondrial coupling of the glycine cleavage complex (GC) and serine hydroxymethyltransferase (SHMT) was confirmed by the formation of three serine isotopomers, [2-(13)C]-, [3-(13)C]- and [2,3-(13)C]serine, detected by 13C-NMR.	Glycine	30-37	serine hydroxymethyltransferase 1	Rattus norvegicus	97-101
8624089-1	1996	A longitudinal MRI study of at-risk members of a family with an amyloid precursor protein 717Val-Gly mutation.	Glycine	97-100	amyloid beta precursor protein	Homo sapiens	64-89
8775804-3	1995	This reduced sensitivity is consistently associated with the presence of two independent mutations in the proteinase gene, glycine--&gt;valine at position 48 and leucine--&gt;methionine at position 90, with the latter predominating in vivo.	Glycine	123-130	endogenous retrovirus group K member 25	Homo sapiens	106-116
8628727-12	1996	The interactions include direct interactions between the GRE and glycine-458 and serine-459, side groups which differentiate GR from other members of the nuclear hormone receptor family.	Glycine	65-72	nuclear receptor subfamily 3 group C member 1	Homo sapiens	57-59
8524794-2	1995	Mutation analysis of mouse inducible NOS (iNOS; NOS2) identified Gly-450 and Ala-453 as critical for NO production, dimer formation, and BH4 binding.	Glycine	65-68	nitric oxide synthase 2, inducible	Mus musculus	27-40
8524794-2	1995	Mutation analysis of mouse inducible NOS (iNOS; NOS2) identified Gly-450 and Ala-453 as critical for NO production, dimer formation, and BH4 binding.	Glycine	65-68	nitric oxide synthase 2, inducible	Mus musculus	42-46
8524794-2	1995	Mutation analysis of mouse inducible NOS (iNOS; NOS2) identified Gly-450 and Ala-453 as critical for NO production, dimer formation, and BH4 binding.	Glycine	65-68	nitric oxide synthase 2, inducible	Mus musculus	48-52
8993775-5	1996	Amino acid analysis indicates that LSF is a peptide composed of Asp, Glu, Ser, Thr, Ala, Gly, Arg and probably Met, with the N-terminus blocked, possibly by pyroglutamic acid.	Glycine	89-92	transcription factor CP2	Mus musculus	35-38
8550313-13	1996	Cell adhesion to fibronectin and vitronectin was inhibited by peptides containing the Arg-Gly-Asp sequence.	Glycine	90-93	fibronectin 1	Homo sapiens	17-28
10608036-1	1996	Arg-Gly-Asp (RGD)-containing peptides and the peptide unique to fibrinogen in the C-terminal domain of the gamma chain are important for fibrinogen binding to platelet membrane glycoprotein (GP) II b/III a.	Glycine	4-7	fibrinogen beta chain	Homo sapiens	137-147
8912473-11	1996	There are actually multiple alleles of the normal AR gene; these allelic variants differ in glutamine and glycine repeat length in the transactivation domain of the protein, and they may differ in signal-transducing activity.	Glycine	106-113	androgen receptor	Homo sapiens	50-52
8903622-8	1995	Furthermore, the use of a specific antagonist of glycine or of the gamma-aminobutyric acid receptor in the rostral ventrolateral medulla attenuated the antihypertensive response induced by the intravenous AT1 antagonist in SHR.	Glycine	49-56	angiotensin II receptor, type 1b	Rattus norvegicus	205-208
7492289-7	1995	However, we did identify an amino acid substitution (glycine to aspartic acid) in exon 9 of the catalase gene in one patient; decreased red blood cell catalase activity was observed in this patient.	Glycine	53-60	catalase	Homo sapiens	96-104
8903622-9	1995	CONCLUSION: The present results suggest that the release of the inhibitory amino acids glycine and gamma-aminobutyric acid in the rostral ventrolateral medulla contributes to the depressor action of this AT1 receptor antagonist in the genetic hypertensive rat model.	Glycine	87-94	angiotensin II receptor, type 1b	Rattus norvegicus	204-207
7553884-14	1995	The presence of IAp residues (glu and thr versus gly and val in IAq) at these sites severely compromised the capacity for protein presentation.	Glycine	49-52	intracisternal A particle, Eya1 linked	Mus musculus	16-19
8529662-4	1995	Sequence analysis showed that ERp57/GRP58 has two Trp-Cys-Gly-His-Cys-Lys motifs completely conserved among the mammals.	Glycine	58-61	protein disulfide isomerase family A member 3	Homo sapiens	30-35
8529662-4	1995	Sequence analysis showed that ERp57/GRP58 has two Trp-Cys-Gly-His-Cys-Lys motifs completely conserved among the mammals.	Glycine	58-61	protein disulfide isomerase family A member 3	Homo sapiens	36-41
7476914-5	1995	Glycine had an approximately 10-fold higher affinity (p &lt; 0.0001) for NR2B- than for NR2A-containing receptors (mKd = 0.057 and 0.53 microM, respectively).	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	88-92
8613724-5	1995	The NMDA receptor modulators glycine and spermidine enhanced glutamate-mediated toxicity whereas ifenprodil potently and completely inhibited toxicity suggesting that the toxic response is mediated by the NR1/NR2B combination of NMDA subunits.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	205-208
8618801-2	1995	Sequencing of the GH releasing hormone (GHRH) receptor in lit/lit mice has shown a single nucleotide substitution within the extracellular peptide binding domain at codon 60 that changed aspartic acid to glycine.	Glycine	204-211	growth hormone releasing hormone	Homo sapiens	40-44
8567184-8	1995	While the glycine and D-proline analogues (relative binding 104 and 143%, respectively) retain the self-association properties typical of insulin, [PheB28]des-(B29-B30)-insulin-B28-amide (relative binding 50%) shows diminished self-association.	Glycine	10-17	insulin	Homo sapiens	138-145
7559573-8	1995	By sequence comparison, six residues, Arg-103, Arg-123, Met-129, Gly-130, Arg-143, and Arg-160, which are conserved in regulated myosin RLCs but missing in nonregulated myosin RLCs, were identified in smRLC.	Glycine	65-68	myosin, heavy chain 9, non-muscle	Gallus gallus	129-135
7559573-8	1995	By sequence comparison, six residues, Arg-103, Arg-123, Met-129, Gly-130, Arg-143, and Arg-160, which are conserved in regulated myosin RLCs but missing in nonregulated myosin RLCs, were identified in smRLC.	Glycine	65-68	myosin, heavy chain 9, non-muscle	Gallus gallus	169-175
7588705-0	1995	Two regions with differential growth-modulating activity in the N-terminal domain of ras GTPase-activating protein (p120GAP) src homology and Gly-Ala-Pro-rich regions.	Glycine	142-145	RAS p21 protein activator 1	Rattus norvegicus	116-123
8560426-1	1995	The possibility to induce specific disruption of activated platelets by binding of porcine pancreatic phospholipase A2 (PLA2) was tested by constructing a set of PLA2-mutants containing an Arg-Gly-Asp (RGD) sequence.	Glycine	193-196	phospholipase A2 group IB	Homo sapiens	102-118
8560426-1	1995	The possibility to induce specific disruption of activated platelets by binding of porcine pancreatic phospholipase A2 (PLA2) was tested by constructing a set of PLA2-mutants containing an Arg-Gly-Asp (RGD) sequence.	Glycine	193-196	phospholipase A2 group IB	Homo sapiens	120-124
7561142-6	1995	Substitution of glycine for amino acid in position 123 (arginine, R), 124 (lysine, K), 126 (R) or 128 (K) in a MAGE-4b oligopeptide of the position 119-132 severely decreased the reactivity of the R5 mAb to the oligopeptide.	Glycine	16-23	MAGE family member A4	Homo sapiens	111-118
7548057-6	1995	The best inhibitors of thrombin contained Pro or Gly at the P2 position in place of Phe353, with 2- and 7-fold increases in activity, respectively.	Glycine	49-52	coagulation factor II, thrombin	Homo sapiens	23-31
7559471-1	1995	N-Myristoyltransferase (NMT) catalyzes the co-translational addition of myristic acid to the N-terminal glycine of many cellular, viral, and fungal proteins which are essential to normal cell functioning and/or are potential therapeutic targets.	Glycine	104-111	N-myristoyltransferase 1	Homo sapiens	24-27
7673195-4	1995	The hnRNP A1, A2/B1, and D0 proteins, all possess common features of the 2xRBD-Gly structure and binding specificity toward RNA.	Glycine	79-82	ATPase H+ transporting V0 subunit a2	Homo sapiens	14-27
8585604-5	1995	Using the anti-hamster beta 1 monoclonal antibody 7E2 to capture alpha 5 beta 1 from a CHO#7 cell lysate, this SPA assay allowed measurement of specific 125I-fibronectin binding as defined by displacement by the Arg-Gly-Asp containing peptide GRGDSP or the anti-human alpha 5 antibody P1D6.	Glycine	216-219	fibronectin 1	Homo sapiens	158-169
7502582-6	1995	DNA sequence comparison reveals also the presence of three known sequences: the Tyl-H3 transposable element, the yeast suf1(+) frameshift suppressor gene for tRNA-Gly and the yeast transfer RNA-Thr-1a.	Glycine	163-166	SUF1	Saccharomyces cerevisiae S288C	119-123
8686881-7	1995	Analysis of the concentration dependence of the electrophoretic mobility of insulin yields a lower limit for the association constant for dimerization of insulin of KD &gt; or = 6 x 10(3) M-1 (25 mM tris and 192 mM Gly, pH 8.4).	Glycine	215-218	insulin	Homo sapiens	76-83
8686881-7	1995	Analysis of the concentration dependence of the electrophoretic mobility of insulin yields a lower limit for the association constant for dimerization of insulin of KD &gt; or = 6 x 10(3) M-1 (25 mM tris and 192 mM Gly, pH 8.4).	Glycine	215-218	insulin	Homo sapiens	154-161
7650066-3	1995	A seven residue peptide containing residues 368-374, Val Tyr Tyr Val Gly Arg Lys, was demonstrated to be capable of inducing chemotactic migration of human peripheral blood neutrophils, monocytes, monocyte leukemia cell line THP-1, and infant foreskin fibroblasts.	Glycine	69-72	GLI family zinc finger 2	Homo sapiens	225-230
8548867-3	1995	The cell adhesive region in the central portion of fibronectin is comprised of at least two minimal amino acid sequences--an Arg-Gly-Asp (RGD) sequence and a Pro-His-Ser-Arg-Asn (PHSRN) sequence--which function in synergy.	Glycine	129-132	fibronectin 1	Homo sapiens	51-62
7556217-4	1995	It belongs to the sulfakinin family, all known members of which (from flies, cockroaches and locusts) have the C-terminal heptapeptide sequence Asp-Tyr(SO3)-Gly-His-Met-Arg-Phe-NH2.	Glycine	157-160	Drosulfakinin	Drosophila melanogaster	18-28
7580763-9	1995	The 15N enrichment of fibrinogen glycine and the hippurate precursor for fibrinogen were decreased significantly.	Glycine	33-40	fibrinogen beta chain	Homo sapiens	22-32
7657661-0	1995	Role of glycine 1 and lysine 2 in the glycation of bovine gamma B-crystallin.	Glycine	8-15	crystallin gamma B	Bos taurus	58-76
7657661-9	1995	Glycation with DL-glyceraldehyde showed an important role for both Gly-1 and Lys-2 in the glycation-mediated gamma B-crystallin cross-linking.	Glycine	0-3	crystallin gamma B	Bos taurus	109-127
7651730-1	1995	An altered protein expression of Ca(2+)-dependent protein kinase C (PKC) isoforms and a point mutation in the PKC alpha cDNA (position 908 of the nucleotide sequence, position 294 of the amino acid sequence, substitution of an aspartic acid by a glycine) have been previously described in a subpopulation of human pituitary tumors.	Glycine	246-253	protein kinase C alpha	Homo sapiens	110-119
7644501-5	1995	A Gly-159--&gt;Ala substitution in BH1 of Bcl-xL disrupted its heterodimerization with Bax and abrogated its inhibition of apoptosis in mammalian cells.	Glycine	2-5	BCL2 like 1	Homo sapiens	42-48
7644501-5	1995	A Gly-159--&gt;Ala substitution in BH1 of Bcl-xL disrupted its heterodimerization with Bax and abrogated its inhibition of apoptosis in mammalian cells.	Glycine	2-5	BCL2 associated X, apoptosis regulator	Homo sapiens	87-90
7641799-1	1995	The small cell lung carcinoma cell line U-1690 bound beta-endorphin via nonopioid binding sites also recognized by the C-terminal part of this opioid peptide Lys-Lys-Gly-Glu, but not by opiate alkaloids such as naloxone and morphine or other opioid peptides.	Glycine	166-169	proopiomelanocortin	Homo sapiens	53-67
7582983-4	1995	Subsequently, penta- and hexapeptide sequences with good affinity for thrombin were developed, i.e. H-D-Phe-Pro-Arg-Gly-Phe-OH (16) and H-D-Phe-Pro-Arg-Gly-Phe-Lys-OH (26).	Glycine	116-119	coagulation factor II, thrombin	Homo sapiens	70-78
7498764-3	1995	The LPD1 gene product is also required for cells to utilize glycine as sole nitrogen source.	Glycine	60-67	dihydrolipoyl dehydrogenase	Saccharomyces cerevisiae S288C	4-8
8569729-1	1995	Myristoyl CoA:Protein N-myristoyltransferase (NMT) is the enzyme which catalyses the covalent transfer of myristate from myristoyl CoA to the amino-terminal glycine residue of protein substrates.	Glycine	157-164	N-myristoyltransferase 1	Homo sapiens	22-44
8569729-1	1995	Myristoyl CoA:Protein N-myristoyltransferase (NMT) is the enzyme which catalyses the covalent transfer of myristate from myristoyl CoA to the amino-terminal glycine residue of protein substrates.	Glycine	157-164	N-myristoyltransferase 1	Homo sapiens	46-49
7622459-5	1995	Purified myeloperoxidase in combination with hydrogen peroxide and chloride, as well as stimulated human neutrophils, chlorinated tyrosine in the peptide Gly-Gly-Tyr-Arg.	Glycine	154-157	myeloperoxidase	Homo sapiens	9-24
24301478-2	1995	The effects of glycine on the kinetic constants for these other effectors were greater than its effect on the Km for substrate, raising the Ki(malate) 11-fold and reducing Ka(glucose6-P) 7-fold, while reducing the Km(PEP) by 3-fold.	Glycine	15-22	phosphoenolpyruvate carboxylase 2	Zea mays	217-220
7636850-3	1995	Novel transition state isosteres with modified P1--&gt;P3 side chains were synthesized and provided enhanced binding affinity when incorporated into renin inhibitors in which the P3 Phe was substituted by Gly.	Glycine	205-208	renin	Homo sapiens	149-154
7622459-5	1995	Purified myeloperoxidase in combination with hydrogen peroxide and chloride, as well as stimulated human neutrophils, chlorinated tyrosine in the peptide Gly-Gly-Tyr-Arg.	Glycine	158-161	myeloperoxidase	Homo sapiens	9-24
7604034-8	1995	The failure of some peptides eluted from DRB1*1302 (those that use aromatic amino acids as primary anchors) to bind to DRB1*1301 confirmed the different preferences for peptide anchor residues conferred by the Gly--&gt;Val change at position 86.	Glycine	210-213	major histocompatibility complex, class II, DR beta 1	Homo sapiens	41-45
7539426-3	1995	The VWF-GPIb interaction was investigated by clustered charged-to-alanine scanning mutagenesis of VWF domain A1 between His-473 and Gly-716.	Glycine	132-135	von Willebrand factor	Homo sapiens	4-7
7549963-3	1995	The optimized assay of SOD is performed in 50 mM glycine-NaOH buffer, pH 9.5, at 25 degrees C. The SOD concentration is determined from the V/v ratio of rates measured in the absence (V) or the presence (v) of SOD.	Glycine	49-56	superoxide dismutase 1	Homo sapiens	23-26
7633467-10	1995	In exon 4, a T to G substitution changes cysteine to glycine and may disrupt a disulphide bond and be responsible for the distinctive properties of GPDH-ACb62.	Glycine	53-60	Glycerol-3-phosphate dehydrogenase 1	Drosophila melanogaster	148-152
7539426-3	1995	The VWF-GPIb interaction was investigated by clustered charged-to-alanine scanning mutagenesis of VWF domain A1 between His-473 and Gly-716.	Glycine	132-135	von Willebrand factor	Homo sapiens	98-101
7796293-4	1995	The HLA-restricted J beta elements are characterized by a Gly-Pro-Gly sequence within the conserved Phe-Gly-X-Gly motif, which induces rigidity in an otherwise more flexible protein backbone.	Glycine	58-61	major histocompatibility complex, class II, DR beta 1	Homo sapiens	4-7
7774057-10	1995	Moreover, TA2 and B12 exhibited two common amino acids in their CDR3 regions, one glycine and one tyrosine, in positions 98 and 99, respectively.	Glycine	82-89	transforming growth factor alpha regulated gene 1	Mus musculus	10-13
7477728-6	1995	Two rare mutations were found in the EVI2A gene, one resulting in an arginine substituting for a glutamine (one control and one patient), the other in the replacement of a glycine with serine (one control only).	Glycine	172-179	ecotropic viral integration site 2A	Homo sapiens	37-42
7662997-4	1995	By molecular analysis of the EC-SOD coding region from the group II individuals in Sweden, a single nucleotide substitution of G to C generating an amino acid change of arginine to glycine has been identified in the region associated with the heparin affinity of the enzyme.	Glycine	181-188	superoxide dismutase 3	Homo sapiens	29-35
7549888-5	1995	The analysis revealed an interesting similarity between the segment around the beta 2-strand of alpha-amylase and the one around the beta 4-strand of glycolate oxidase that are flanked in loops by glycines and prolines.	Glycine	197-205	hydroxyacid oxidase 2	Homo sapiens	150-167
7752183-4	1995	Since the 400-411 sequence is required for gamma-chain bioactivity and is a unique recognition sequence among ligands for integrins, vis-a-vis other RGD (Arg-Gly-Asp)-presenting proteins, these turn mimetics may represent a new, selective approach to antagonism of the fibrinogen receptor.	Glycine	158-161	fibrinogen beta chain	Homo sapiens	269-279
7744746-1	1995	Biologically active amidated gastrin is synthesized by carboxyl-terminal alpha-amidation of a glycine-extended progastrin post-translational processing intermediate (G-Gly).	Glycine	94-101	gastrin	Canis lupus familiaris	29-36
7744746-12	1995	Gastrin peptides truncated at the carboxyl- (G1-13) and amino terminus (G5-17-Gly) both induced H+,K(+)-ATPase alpha-subunit gene expression and inhibited 125I-Leu15-G2-17-Gly binding, but were less potent than G2-17-Gly.	Glycine	78-81	gastrin	Canis lupus familiaris	0-7
7744746-12	1995	Gastrin peptides truncated at the carboxyl- (G1-13) and amino terminus (G5-17-Gly) both induced H+,K(+)-ATPase alpha-subunit gene expression and inhibited 125I-Leu15-G2-17-Gly binding, but were less potent than G2-17-Gly.	Glycine	172-175	gastrin	Canis lupus familiaris	0-7
8612192-1	1995	Three kinds of missense mutation at codon 717 of amyloid precursor protein (APP) gene (Val --> Ile; Val --> Gly; Val --> Phe) were screened in 114 patients with familial and sporadic Alzheimer"s disease (AD), using a rapid testing method for each Val --> Gly and Val --> Phe mutation and Goate"s method for Val --> Ile mutation based on the polymerase chain reaction.	Glycine	108-111	amyloid beta precursor protein	Homo sapiens	49-74
8612192-1	1995	Three kinds of missense mutation at codon 717 of amyloid precursor protein (APP) gene (Val --> Ile; Val --> Gly; Val --> Phe) were screened in 114 patients with familial and sporadic Alzheimer"s disease (AD), using a rapid testing method for each Val --> Gly and Val --> Phe mutation and Goate"s method for Val --> Ile mutation based on the polymerase chain reaction.	Glycine	255-258	amyloid beta precursor protein	Homo sapiens	49-74
7744836-6	1995	For example, replacement of the P2 proline of Arg-alpha 1-antitrypsin by glycine decreased the association rate constant (kass) with thrombin by 37-fold while the kass value with APC was reduced by only 16-fold.	Glycine	73-80	serpin family A member 1	Homo sapiens	50-69
7744836-6	1995	For example, replacement of the P2 proline of Arg-alpha 1-antitrypsin by glycine decreased the association rate constant (kass) with thrombin by 37-fold while the kass value with APC was reduced by only 16-fold.	Glycine	73-80	coagulation factor II, thrombin	Homo sapiens	133-141
7744836-11	1995	Substitution of proline for the P2 glycine of this chimeric serpin increased the kass values with thrombin and APC by 7- and 90-fold, respectively.	Glycine	35-42	coagulation factor II, thrombin	Homo sapiens	98-106
7744733-5	1995	A triple mutation, Asn-Asp-Gly-Gly instead of Arg-His-Gly-Arg, completely abolishes the capacity of the peptide P-(145-159) to elute AChE from the heparin column.	Glycine	27-30	acetylcholinesterase (Cartwright blood group)	Homo sapiens	133-137
7744733-5	1995	A triple mutation, Asn-Asp-Gly-Gly instead of Arg-His-Gly-Arg, completely abolishes the capacity of the peptide P-(145-159) to elute AChE from the heparin column.	Glycine	31-34	acetylcholinesterase (Cartwright blood group)	Homo sapiens	133-137
7749766-6	1995	Fibrinogen was purified via glycine precipitation, and the sialic acid (SA) content was determined.	Glycine	28-35	fibrinogen beta chain	Homo sapiens	0-10
8589260-2	1995	We constructed plasmids encoding circularly permuted IL-4 mutants with the peptide Gly-Gly-Asn-Gly-Gly (GGNGG) joining the carboxyl to the amino terminus and with new amino and carboxyl termini elsewhere.	Glycine	83-86	interleukin 4	Homo sapiens	53-57
8589260-2	1995	We constructed plasmids encoding circularly permuted IL-4 mutants with the peptide Gly-Gly-Asn-Gly-Gly (GGNGG) joining the carboxyl to the amino terminus and with new amino and carboxyl termini elsewhere.	Glycine	87-90	interleukin 4	Homo sapiens	53-57
7744249-8	1995	The functional importance of these repeat motifs is shown by the fact that five of the spe-26 mutations are in the tandem repeats, and one of the most severe mutations is a substitution in a highly conserved glycine.	Glycine	208-215	Spermatocyte protein spe-26	Caenorhabditis elegans	87-93
7731966-2	1995	Of five Sp alleles, Splotch-delayed (Spd) is the only one that encodes a full-length Pax-3 protein, containing a single glycine-to-arginine substitution within the paired domain.	Glycine	120-127	paired box 3	Mus musculus	20-27
7707501-7	1995	We show here that a mutation converting this cysteine to a glycine completely abolishes del3-mpl oncogenicity and that the del3-mpl oncogene product is constitutively activated by disulfide-linked homodimerization.	Glycine	59-66	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	69-72
7707501-7	1995	We show here that a mutation converting this cysteine to a glycine completely abolishes del3-mpl oncogenicity and that the del3-mpl oncogene product is constitutively activated by disulfide-linked homodimerization.	Glycine	59-66	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	93-96
7731966-2	1995	Of five Sp alleles, Splotch-delayed (Spd) is the only one that encodes a full-length Pax-3 protein, containing a single glycine-to-arginine substitution within the paired domain.	Glycine	120-127	paired box 3	Mus musculus	85-90
7536038-7	1995	(ii) Substitution of the C-flanking glycine in GKGRGL (residues 104-109 of myelin basic protein) with histidine, phenylalanine, lysine or aspartic acid completely abolished the ability of these hexapeptides to serve as substrates.	Glycine	36-43	myelin basic protein	Bos taurus	75-95
7721737-9	1995	The mitogenic potency of 0.1-1.0 nM gastrin-like peptides on Swiss 3T3 cells was in the order of G1-17 &gt; or = G1-17-Gly &gt; G5-17 &gt; or = G5-17-Gly &gt; G2-17 &gt; CCK-8-Gly &gt; or = G1-17-Lys &gt; or = CCK-8.	Glycine	119-122	gastrin	Mus musculus	36-43
7721737-12	1995	Based on these studies it became evident that the novel gastrin preferring GR, expressed by Swiss 3T3 cells, binds and mediates the mitogenic effects of not only the mature (amidated) forms of gastrin-like peptides but also binds and mediates the mitogenic effects of glycine-extended forms of gastrin-like peptides.	Glycine	268-275	gastrin	Mus musculus	56-63
7721737-12	1995	Based on these studies it became evident that the novel gastrin preferring GR, expressed by Swiss 3T3 cells, binds and mediates the mitogenic effects of not only the mature (amidated) forms of gastrin-like peptides but also binds and mediates the mitogenic effects of glycine-extended forms of gastrin-like peptides.	Glycine	268-275	gastrin	Mus musculus	193-200
7721737-12	1995	Based on these studies it became evident that the novel gastrin preferring GR, expressed by Swiss 3T3 cells, binds and mediates the mitogenic effects of not only the mature (amidated) forms of gastrin-like peptides but also binds and mediates the mitogenic effects of glycine-extended forms of gastrin-like peptides.	Glycine	268-275	gastrin	Mus musculus	193-200
7536039-6	1995	The glycine-containing peptide was the best substrate having a specificity 16,000-fold higher than 5Val-angiotensin II, the most commonly used peptide substrate.	Glycine	4-11	angiotensinogen	Homo sapiens	104-118
7798019-2	1995	C-terminal amidation of glycine extended gastrin (G-gly) to gastrin amide (G-amide) by peptidylglycine alpha-amidating mono-oxygenase (PAM) is the final processing step.	Glycine	24-31	gastrin	Ovis aries	41-48
7720475-5	1995	DRB1*1501 and DRB1*1502 differ in only one amino acid at residue 86 (valine vs glycine), and 66% of the UC patients carried two glycines at position 86 in the HLA-DR beta-chain (vs 51% of control; P &lt; 0.05).	Glycine	79-86	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-4
7720475-5	1995	DRB1*1501 and DRB1*1502 differ in only one amino acid at residue 86 (valine vs glycine), and 66% of the UC patients carried two glycines at position 86 in the HLA-DR beta-chain (vs 51% of control; P &lt; 0.05).	Glycine	79-86	major histocompatibility complex, class II, DR beta 1	Homo sapiens	14-18
7720475-5	1995	DRB1*1501 and DRB1*1502 differ in only one amino acid at residue 86 (valine vs glycine), and 66% of the UC patients carried two glycines at position 86 in the HLA-DR beta-chain (vs 51% of control; P &lt; 0.05).	Glycine	128-136	major histocompatibility complex, class II, DR beta 1	Homo sapiens	14-18
7720475-5	1995	DRB1*1501 and DRB1*1502 differ in only one amino acid at residue 86 (valine vs glycine), and 66% of the UC patients carried two glycines at position 86 in the HLA-DR beta-chain (vs 51% of control; P &lt; 0.05).	Glycine	128-136	major histocompatibility complex, class II, DR beta 1	Homo sapiens	159-162
7720475-6	1995	These observations suggest that the presence of Gly-86 in the HLA beta-chain and surrounding amino acid sequence of HLA-DRB1*1502 is strongly associated with susceptibility to UC.	Glycine	48-51	major histocompatibility complex, class II, DR beta 1	Homo sapiens	116-124
7897227-6	1995	From the amino acid sequence of the dodecapeptide Gly-Ser-Val-Ser-Asp-Glu-Glu-Met-Met-Glu-Leu-Arg, the phosphorylation site of pp65 was located at the N-terminal region adjacent to the first Ca2+ binding domain.	Glycine	50-53	lymphocyte cytosolic protein 1	Mus musculus	127-131
7798019-2	1995	C-terminal amidation of glycine extended gastrin (G-gly) to gastrin amide (G-amide) by peptidylglycine alpha-amidating mono-oxygenase (PAM) is the final processing step.	Glycine	24-31	gastrin	Ovis aries	60-67
7651140-3	1995	Mutations in residues that are invariant or highly conserved in the ATP-binding fold and glycine-rich linker peptide of prokaryotic and eukaryotic ABC transporters caused a complete loss of both HlyB exporter function and ATPase activity in proteins still able to bind ATP effectively and undergo ATP-induced conformational change.	Glycine	89-96	hemolysin transport protein	Escherichia coli	195-199
7698320-3	1995	Kinetic modelling of inhibition data, gel electrophoresis and amino acid sequencing revealed that reappearance of papain activity is due to selective cleavage of the Gly(9)-Ala10 bond in the N-terminal binding area of the chicken cystatin variants, resulting in truncated inhibitors of lower affinity.	Glycine	166-169	cystatin C	Gallus gallus	230-238
7891694-7	1995	The ERCC1-binding domain on XPA was previously mapped to a region containing two highly conserved XPA sequences, Gly-72 to Phe-75 and Glu-78 to Glu-84, which are termed the G and E motifs, respectively.	Glycine	113-116	XPA, DNA damage recognition and repair factor	Homo sapiens	28-31
7862439-6	1995	By domain swapping and site-directed mutagenesis we identified a single point mutation in the 124 v-Mos protein (Arg145--&gt;Gly) which is responsible for its constitutive activity.	Glycine	125-128	Moloney sarcoma oncogene	Mus musculus	100-103
7702639-3	1995	This stimulation was blocked by glutamate antagonists and potentiated by glycine with an EC50 of approximately 0.03 muM.	Glycine	73-80	latexin	Homo sapiens	116-119
7702639-4	1995	Glycine also had a direct stimulatory effect on [3H]MK-801 binding at much higher concentrations ( &gt; or = 10 muM).	Glycine	0-7	latexin	Homo sapiens	112-115
7702639-8	1995	Inclusion of glycine in the incubation medium markedly attenuated anesthetic-induced inhibition of glutamate-sensitive [3H]MK-801 binding with an EC50 of between 0.1 and 1 muM.	Glycine	13-20	latexin	Homo sapiens	172-175
7866993-3	1995	Substrate specificity of the MDR1 gene product can be altered by a point mutation at amino acid residue 185 in which valine is substituted for glycine, but the effect of this mutation on inhibition of PGP is unknown.	Glycine	143-150	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	29-33
7533788-5	1995	One gene (p542) encodes a protein containing a glycine-rich 28-mer, which is its chief autoantigenic epitope and which represents a newly identified class of evolutionarily conserved autoepitopes.	Glycine	47-54	RALY heterogeneous nuclear ribonucleoprotein	Homo sapiens	10-14
7533789-4	1995	During infectious mononucleosis, IgM autoantibodies are generated to a protein, p542, which contains a glycine-rich 28-mer epitope cross-reactive with the Epstein-Barr nuclear antigen-1 through Epstein-Barr nuclear antigen-1"s glycine/alanine repeat.	Glycine	103-110	RALY heterogeneous nuclear ribonucleoprotein	Homo sapiens	80-84
7533789-4	1995	During infectious mononucleosis, IgM autoantibodies are generated to a protein, p542, which contains a glycine-rich 28-mer epitope cross-reactive with the Epstein-Barr nuclear antigen-1 through Epstein-Barr nuclear antigen-1"s glycine/alanine repeat.	Glycine	227-234	RALY heterogeneous nuclear ribonucleoprotein	Homo sapiens	80-84
7533789-7	1995	The reactive epitopes on p542 were mapped with deletion mutants, which indicated that the glycine-rich 28-mer was the major antigenic determinant, with lesser antibody responses to other epitopes.	Glycine	90-97	RALY heterogeneous nuclear ribonucleoprotein	Homo sapiens	25-29
7780654-7	1995	3. pH-dependent [14C]-Gly-Sar transport was inhibited by the orally-active ACE inhibitors, enalapril maleate and captopril (both at 20 mM).	Glycine	22-25	angiotensin I converting enzyme	Homo sapiens	75-78
7780654-15	1995	The effects of enalapril maleate and captopril on [14C]-Gly-Sar transport and pHi suggest that these two ACE inhibitors share the H(+)-coupled mechanism involved in dipeptide transport.	Glycine	56-59	angiotensin I converting enzyme	Homo sapiens	105-108
7533293-2	1995	We confirm that wa-2 is a point mutation (T--&gt;G resulting in a valine--&gt;glycine substitution at residue 743) in the gene encoding the epidermal growth factor (EGF) receptor.	Glycine	78-85	epidermal growth factor receptor	Homo sapiens	140-178
7876565-6	1995	IgE was eluted with 0.05 M glycine pH 2.8 and immediately neutralized.	Glycine	27-34	immunoglobulin heavy constant epsilon	Homo sapiens	0-3
7862439-9	1995	We hypothesize that the Arg145--&gt;Gly mutation found in 124 v-Mos mimicks a conformational change which might be an obligatory step in the activation of c-Mos in vivo.	Glycine	36-39	Moloney sarcoma oncogene	Mus musculus	64-67
7862439-9	1995	We hypothesize that the Arg145--&gt;Gly mutation found in 124 v-Mos mimicks a conformational change which might be an obligatory step in the activation of c-Mos in vivo.	Glycine	36-39	Moloney sarcoma oncogene	Mus musculus	155-160
7756179-7	1995	To mimic the temperature-sensitive mutant of yeast nuc2, an H-NUC mutant was made in which the highly conserved glycine 640 residue was changed to aspartic acid.	Glycine	112-119	tRNA (uracil(54)-C(5))-methyltransferase	Saccharomyces cerevisiae S288C	51-55
7538414-2	1995	We have expressed a recombinant 20 kDa cell-binding fragment of human fibronectin consisting of the ninth and tenth type III modules, which includes the Arg-Gly-Asp (RGD) cell recognition site and a second cell adhesive domain that acts synergistically with the RGD site.	Glycine	157-160	fibronectin 1	Homo sapiens	70-81
7734427-2	1995	One of these results in a Ser--&gt;Gly amino acid difference in CH1 at position 129 according to the Wu and Kabat numbering system.	Glycine	35-38	immediate early response 2	Mus musculus	64-67
7818527-0	1995	Highly conserved aspartate 68, tryptophane 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP.	Glycine	50-57	vasoactive intestinal peptide	Homo sapiens	114-117
7870047-0	1995	Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site.	Glycine	102-109	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	67-70
7870047-4	1995	We have used site-directed mutagenesis to study amino acids in the human NR1 subunit that contribute to the glycine binding site of the NMDA receptor without affecting the agonist site for glutamate.	Glycine	108-115	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	73-76
7833348-5	1995	Incubation of COS cells transiently transfected with a full-length clone of the GLYT1 transporter in the presence of TPA, produces a decrease in glycine uptake.	Glycine	145-152	solute carrier family 6 member 9	Homo sapiens	80-85
8590320-0	1995	Overcoming the metastasis-enhancing potential of human tumor necrosis factor alpha by introducing the cell-adhesive Arg-Gly-Asp sequence.	Glycine	120-123	tumor necrosis factor	Homo sapiens	55-82
8590320-1	1995	A mutein, F4168, of human tumor necrosis factor alpha (hTNF-alpha) containing the cell-adhesive Arg-Gly-Asp (RGD) sequence near the N terminus was constructed.	Glycine	100-103	tumor necrosis factor	Homo sapiens	26-53
8590320-1	1995	A mutein, F4168, of human tumor necrosis factor alpha (hTNF-alpha) containing the cell-adhesive Arg-Gly-Asp (RGD) sequence near the N terminus was constructed.	Glycine	100-103	tumor necrosis factor	Homo sapiens	55-65
7846071-0	1995	Dark-light: model for nightblindness from the human rhodopsin Gly-90--&gt;Asp mutation.	Glycine	62-65	rhodopsin	Homo sapiens	52-61
7846071-1	1995	A human rhodopsin mutation, Gly-90--&gt;Asp (Gly90Asp), cosegregated with an unusual trait of congenital nightblindness in 22 at-risk members of a large autosomal dominant kindred.	Glycine	28-31	rhodopsin	Homo sapiens	8-17
7818527-0	1995	Highly conserved aspartate 68, tryptophane 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP.	Glycine	50-57	vasoactive intestinal peptide	Homo sapiens	165-168
7711926-0	1995	The relationship between glycine and gephyrin in synapses of the rat spinal cord.	Glycine	25-32	gephyrin	Rattus norvegicus	37-45
7734198-7	1995	Here, we also show that single cysteine-to-glycine substitutions at positions 28, 32, or 55 drastically reduced covalent Nef dimer formation and thermal stability of the Nef protein in vitro.	Glycine	43-50	S100 calcium binding protein B	Homo sapiens	121-124
7734198-7	1995	Here, we also show that single cysteine-to-glycine substitutions at positions 28, 32, or 55 drastically reduced covalent Nef dimer formation and thermal stability of the Nef protein in vitro.	Glycine	43-50	S100 calcium binding protein B	Homo sapiens	170-173
7611876-5	1995	Furthermore, the polypeptide ORF2 (26.9 kDa) has an unusual primary structure consisting of 3 stretches of acidic amino acid residues and a glycine/arginine rich C-terminal end.	Glycine	140-147	ORF2	Streptomyces phage VWB	29-33
7828531-4	1995	Two forms of POMC cDNA have been identified; one sequence agrees with the cDNA sequence predicted from the published genomic sequence, and the second is a variant with a 9-base pair deletion (corresponding to the loss of three amino acids, Ser-Ser-Gly, between residues 67-73).	Glycine	248-251	proopiomelanocortin	Homo sapiens	13-17
8922270-1	1995	Esters of pyrroloquinoline quinone (PQQ), a cofactor of microbial quinoprotein enzyme, and imidazopyrroloquinoline (IPQ, from PQQ and glycine) were synthesized, and their chemical stability, toxicity to L-M cells and nerve growth factor (NGF) inducing activity in L-M cells were studied.	Glycine	134-141	nerve growth factor	Homo sapiens	217-236
8922270-1	1995	Esters of pyrroloquinoline quinone (PQQ), a cofactor of microbial quinoprotein enzyme, and imidazopyrroloquinoline (IPQ, from PQQ and glycine) were synthesized, and their chemical stability, toxicity to L-M cells and nerve growth factor (NGF) inducing activity in L-M cells were studied.	Glycine	134-141	nerve growth factor	Homo sapiens	238-241
7711926-1	1995	In order to examine the relationship between gephyrin (the peripheral membrane protein associated with glycine receptors) and glycinergic boutons, we have carried out a post-embedding immunogold study of glycine-like immunoreactivity on sections of rat lumbar spinal cord which had previously been reacted with monoclonal antibody to gephyrin.	Glycine	103-110	gephyrin	Rattus norvegicus	45-53
7711926-2	1995	In all three areas examined (laminae I and II, lamina III and lamina IX) the majority of profiles which were presynaptic at gephyrin-immunoreactive synapses were enriched with glycine-like immunoreactivity.	Glycine	176-183	gephyrin	Rattus norvegicus	124-132
7711926-3	1995	It was estimated that at least 83% of profiles presynaptic to gephyrin-immunoreactive synapses in the superficial dorsal horn (laminae I and II) were glycine-immunoreactive, while for lamina III and the ventral horn (lamina IX) the proportions were at least 91% and 98% respectively.	Glycine	150-157	gephyrin	Rattus norvegicus	62-70
7711926-4	1995	This provides strong evidence that glycine is a transmitter at those synapses where gephyrin- and glycine-like immunoreactivities are both present, but suggests that gephyrin may sometimes be expressed at non-glycinergic synapses and indicates the need for caution in using gephyrin-immunoreactivity as a marker for glycinergic synapses within the spinal cord.	Glycine	35-42	gephyrin	Rattus norvegicus	84-92
7711926-4	1995	This provides strong evidence that glycine is a transmitter at those synapses where gephyrin- and glycine-like immunoreactivities are both present, but suggests that gephyrin may sometimes be expressed at non-glycinergic synapses and indicates the need for caution in using gephyrin-immunoreactivity as a marker for glycinergic synapses within the spinal cord.	Glycine	35-42	gephyrin	Rattus norvegicus	166-174
7711926-4	1995	This provides strong evidence that glycine is a transmitter at those synapses where gephyrin- and glycine-like immunoreactivities are both present, but suggests that gephyrin may sometimes be expressed at non-glycinergic synapses and indicates the need for caution in using gephyrin-immunoreactivity as a marker for glycinergic synapses within the spinal cord.	Glycine	35-42	gephyrin	Rattus norvegicus	166-174
8924422-1	1995	The adhesive proteins fibrinogen (FG) and fibronectin (FN) were immobilized to glycine-Sephadex G-10.	Glycine	79-86	fibrinogen beta chain	Homo sapiens	22-32
8808011-3	1995	Long-term treatment with human recombinant growth hormone normalized plasma alanine, glutamine, and glutamic acid levels, increased the OH-Pro concentration, and did not alter the amino acid ratios of Gly/Val, Phe/Tyr, Ser/Gly, and Asn/Asp, but the Gln/Glu ratio approached the normal value.	Glycine	223-226	growth hormone 1	Homo sapiens	43-57
7830031-4	1995	One of these is an exon 15 missense mutation, changing amino acid 442 of CETP from aspartate to glycine.	Glycine	96-103	cholesteryl ester transfer protein	Homo sapiens	73-77
7844520-7	1995	For hd1, a potential fusogenic role is suggested by the conserved positional pattern of glycine residues, which is comparable to that of known fusion peptides of other viruses.	Glycine	88-95	histone deacetylase 1	Homo sapiens	4-7
7474896-11	1995	Clearly, in 3-MCC deficiency the available glycine and carnitine pools are not sufficient to meet the potential for conjugation of accumulated metabolites, suggesting a possible therapeutic role for glycine and carnitine therapy in this disorder.	Glycine	43-50	MCC regulator of WNT signaling pathway	Homo sapiens	14-17
7474896-11	1995	Clearly, in 3-MCC deficiency the available glycine and carnitine pools are not sufficient to meet the potential for conjugation of accumulated metabolites, suggesting a possible therapeutic role for glycine and carnitine therapy in this disorder.	Glycine	199-206	MCC regulator of WNT signaling pathway	Homo sapiens	14-17
21043620-4	1995	Thrombin-stimulated platelets but not non-stimulated platelets adhered to the SCSb-9coated surface, and platelet adherence was inhibited in a dose-dependent manner by the tetrapeptide RGDS (Arg-Gly-Asp-Ser).	Glycine	194-197	coagulation factor II, thrombin	Homo sapiens	0-8
7885191-0	1995	Drosophila GABA-gated chloride channel: modified [3H]EBOB binding site associated with Ala--&gt;Ser or Gly mutants of Rdl subunit.	Glycine	103-106	Resistant to dieldrin	Drosophila melanogaster	118-121
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	87-94	parathyroid hormone	Homo sapiens	37-41
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	87-94	parathyroid hormone	Homo sapiens	100-104
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	87-94	parathyroid hormone	Homo sapiens	100-104
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	96-99	parathyroid hormone	Homo sapiens	37-41
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	96-99	parathyroid hormone	Homo sapiens	100-104
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	96-99	parathyroid hormone	Homo sapiens	100-104
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	127-130	parathyroid hormone	Homo sapiens	37-41
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	127-130	parathyroid hormone	Homo sapiens	100-104
8532584-1	1995	We have produced and characterized a hPTH analogue with an amino-terminal extension of glycine, Gly-hPTH(-1--&gt;+84) (denoted Gly-hPTH).	Glycine	127-130	parathyroid hormone	Homo sapiens	100-104
7987849-9	1994	As a consequence the normally nontranslated exon 2 is translated and in both types there is in the junction between FUS and CHOP a shift from a FUS glycine codon to a valine codon in the chimeric mRNA.	Glycine	148-155	FUS RNA binding protein	Homo sapiens	116-119
7884961-5	1995	Point mutation at codon 54 [Exon 2, GAC (Asp)--&gt;GGC(Gly)] was also demonstrated on the beta-sheet of CK-MM.	Glycine	55-58	creatine kinase, M-type	Homo sapiens	104-109
7987849-9	1994	As a consequence the normally nontranslated exon 2 is translated and in both types there is in the junction between FUS and CHOP a shift from a FUS glycine codon to a valine codon in the chimeric mRNA.	Glycine	148-155	DNA damage inducible transcript 3	Homo sapiens	124-128
7987849-9	1994	As a consequence the normally nontranslated exon 2 is translated and in both types there is in the junction between FUS and CHOP a shift from a FUS glycine codon to a valine codon in the chimeric mRNA.	Glycine	148-155	FUS RNA binding protein	Homo sapiens	144-147
7982943-7	1994	Automated sequence analysis showed that both modified peptide fractions were derived from the same sequence in AST IV: 63-Leu-Glu-Lys-Cys-Gly-Arg-68.	Glycine	138-141	sulfotransferase family 1A member 1	Rattus norvegicus	111-117
7992055-3	1994	In three of the four AMPA receptor subunits (GluR-B, -C, and -D), intronic elements determine a codon switch (AGA, arginine, to GGA, glycine) in the primary transcripts in a position termed the R/G site, which immediately precedes the alternatively spliced modules "flip" and "flop."	Glycine	133-140	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	45-51
7881430-0	1994	Identification of a homozygous missense mutation (Arg to Gly) in the critical binding region of the human EC-SOD gene (SOD3) and its association with dramatically increased serum enzyme levels.	Glycine	57-60	superoxide dismutase 3	Homo sapiens	106-112
9098452-5	1994	In our case report predisposition to cutaneous idiopathic lichen planus is correlated with a valine in position 85 and a glycine in position 86 at the second exon of the DRB1 gene.	Glycine	121-128	major histocompatibility complex, class II, DR beta 1	Homo sapiens	170-174
7881430-0	1994	Identification of a homozygous missense mutation (Arg to Gly) in the critical binding region of the human EC-SOD gene (SOD3) and its association with dramatically increased serum enzyme levels.	Glycine	57-60	superoxide dismutase 3	Homo sapiens	119-123
7537125-7	1994	External calcium ion and temperature dependence of adhesion together with the observation that RGD (Arg, Gly, Asp)--containing peptide blocked cell binding to FN suggests that FC epsilon RI crosslinking-induced adhesion potentiation involves an integrin type receptor on cell surface.	Glycine	105-108	Fc receptor, IgE, high affinity I, alpha polypeptide	Mus musculus	176-189
7957263-4	1994	Human neurone-specific DnaJ-like proteins, HSJ1a and HSJ1b, possess a J domain and a glycine/phenylalanine-rich region in common with E. coli DnaJ, although the overall amino acid identity is less than 23%.	Glycine	85-92	DnaJ heat shock protein family (Hsp40) member B2	Homo sapiens	53-58
7957243-4	1994	Alignment of zeta-crystallins/quinone oxidoreductases/VAT-1 reveals 38 strictly conserved residues, of which approximately half are glycine residues, including those at several space-restricted turn positions and critical coenzyme-binding positions in the alcohol dehydrogenases.	Glycine	132-139	vesicle amine transport 1	Homo sapiens	54-59
7756983-11	1994	In PPACK-thrombin, the side chain of Asp 189 and the segment Arg 221A-Gly 223 move to provide space for the inhibitor, whereas in hirugen-thrombin, the Ala 190-Gly 197 movement expands the active site region.	Glycine	70-73	coagulation factor II, thrombin	Homo sapiens	9-17
7720110-3	1994	The result showed that mutation of both cell lines occurred on the 154th codon in exon5 of p53 gene, where GGC was displaced by GTC resulting a substitution of Val for Gly, nevertheless, N-ras oncogene and the exon7 of p53 gene are normal.	Glycine	168-171	tumor protein p53	Homo sapiens	91-94
7720110-3	1994	The result showed that mutation of both cell lines occurred on the 154th codon in exon5 of p53 gene, where GGC was displaced by GTC resulting a substitution of Val for Gly, nevertheless, N-ras oncogene and the exon7 of p53 gene are normal.	Glycine	168-171	tumor protein p53	Homo sapiens	219-222
7534472-1	1994	A T-cell stimulating peptide Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH, the 163-171 fragment epitope of interleukin-1 beta (IL-1 beta), has been synthesized in solution phase and purified by reverse-phase high-performance liquid chromatography (RP-HPLC).	Glycine	37-40	interleukin 1 beta	Homo sapiens	101-119
7971977-4	1994	NR1(011)/NR2A receptors exhibited only the increase in glycine affinity, and NR1(011)/NR2C receptors exhibited neither.	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	9-13
7971977-5	1994	As for NR1(100) homomers, NR1(100)/NR2B and NR1(100)/NR2A receptors exhibited spermine potentiation only by increasing the glycine affinity.	Glycine	123-130	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	53-57
7971977-7	1994	Thus, the NR2B subunit "permits" both forms of spermine potentiation, the NR2A subunit permits spermine potentiation only by increasing the glycine affinity, and th NR2C subunit permits neither form of potentiation.	Glycine	140-147	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	74-78
7713748-0	1994	Hb A2-Sant" Antioco [alpha 2 delta (2)93(F9)Cys-->Gly]: a new delta chain variant identified by sequencing of amplified DNA.	Glycine	50-53	glycoprotein hormone subunit alpha 2	Homo sapiens	3-34
7929438-1	1994	Latency of matrix metalloproteinase 3 (MMP-3) is regulated by the interaction of a free cysteine residue (Cys-75) in the conserved amino acid sequence Pro-Arg-Cys-Gly-Val-Pro-Asp located in the COOH-terminal portion of the propeptide with a chelated zinc atom in the active site of the catalytic domain.	Glycine	163-166	matrix metallopeptidase 3	Homo sapiens	11-37
7929438-1	1994	Latency of matrix metalloproteinase 3 (MMP-3) is regulated by the interaction of a free cysteine residue (Cys-75) in the conserved amino acid sequence Pro-Arg-Cys-Gly-Val-Pro-Asp located in the COOH-terminal portion of the propeptide with a chelated zinc atom in the active site of the catalytic domain.	Glycine	163-166	matrix metallopeptidase 3	Homo sapiens	39-44
7874121-4	1994	Glra1 assembles into a pentameric complex with the beta subunit of the glycine receptor (3 alpha (1)2 beta 5) to form a glycine-gated chloride channel.	Glycine	71-78	glycine receptor, alpha 1 subunit	Mus musculus	0-5
7753595-3	1994	Decomplexed p24 antigenemia was detected in 34% of patients after dissociation of circulating immune complexes (CIC) by HC1 (p &lt; 0.01) and in 44% of patients after dissociation of CIC by glycine (p &lt; 0.001).	Glycine	190-197	transmembrane p24 trafficking protein 2	Homo sapiens	12-15
7753595-4	1994	However, the mean concentration of decomplexed p24 antigenemia of positive sera was higher after pretreatment by HC1 (88 pg/ml) than by glycine (52 pg/ml), suggesting that a strong acid is more convenient than a weak one to disrupt the CIC in Black individuals.	Glycine	136-143	transmembrane p24 trafficking protein 2	Homo sapiens	47-50
7841367-1	1994	We have previously shown that a metabolically stable analogue of MPF, the C-terminal tetrapeptide of human beta-endorphin of structure Lys-Lys-Gly-Glu, reduces the turning behaviour of rats with unilateral lesions of their nigro-striatal pathways.	Glycine	143-146	proopiomelanocortin	Homo sapiens	107-121
7534472-1	1994	A T-cell stimulating peptide Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH, the 163-171 fragment epitope of interleukin-1 beta (IL-1 beta), has been synthesized in solution phase and purified by reverse-phase high-performance liquid chromatography (RP-HPLC).	Glycine	37-40	interleukin 1 beta	Homo sapiens	121-130
8083978-1	1994	Within vaccinia virus-infected cells, the product of the L1R open reading frame is covalently modified by myristic acid at the penultimate NH2-terminal glycine residue.	Glycine	152-159	IMV membrane protein	Vaccinia virus	57-60
7527054-4	1994	Fibronectin contains at least three distinct peptide sequences that are active sites for alpha 4 beta 1 binding, two homologous sequences Leu-Asp-Val-Pro (LDVP) and Ile-Asp-Ala-Pro (IDAP), and a third related to Arg-Gly-Asp (RGD).	Glycine	216-219	fibronectin 1	Homo sapiens	0-11
7935404-0	1994	Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain.	Glycine	92-99	epidermal growth factor receptor	Homo sapiens	14-18
7935404-4	1994	This mutation lies at position 157 of the insertionally activated c-erbB product, affecting a highly conserved valine residue of the glycine loop involved in ATP binding and phosphate transfer.	Glycine	133-140	epidermal growth factor receptor	Homo sapiens	68-72
8089125-5	1994	In contrast, mutations of residues 12 (Gly--&gt;Val) or 61 (Gln--&gt;Leu) inhibit both intrinsic- and GAP-stimulated GTP hydrolysis by Rac2.	Glycine	39-42	Rac family small GTPase 2	Homo sapiens	135-139
8063713-5	1994	The first of these substrates, NFF-1 (Mca-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Lys-(Dnp)-Gly, where Mca is (7-methoxycoumarin-4-yl)acetyl and Dnp is 2,4-dinitrophenyl), was hydrolyzed equally well by MMP-3 and MMP-2 (kcat/Km approximately 11,000 s-1 M-1).	Glycine	70-73	matrix metallopeptidase 3	Homo sapiens	199-204
8049421-2	1994	In patient B, the sequencing of both exons 15 and 16 of the vWF gene showed two sequence alterations: a 3-bp insertion in exon 15 resulting in the insertion of a Glycine at position 625 (625insGly) and a 2-bp deletion in exon 16 leading to a premature translational stop at codon 711 (711 ter), at the heterozygote state.	Glycine	162-169	von Willebrand factor	Homo sapiens	60-63
7923585-3	1994	Among the 12 bile acids tested, our results showed that unconjugated CDCA and LCA and the glycine and taurine conjugates of LCA (g-LCA, t-LCA) were able to bind covalently with naked DNA in vitro without intervention of any catalyst.	Glycine	90-97	clathrin light chain A	Homo sapiens	124-127
7923585-3	1994	Among the 12 bile acids tested, our results showed that unconjugated CDCA and LCA and the glycine and taurine conjugates of LCA (g-LCA, t-LCA) were able to bind covalently with naked DNA in vitro without intervention of any catalyst.	Glycine	90-97	clathrin light chain A	Homo sapiens	129-134
7923585-3	1994	Among the 12 bile acids tested, our results showed that unconjugated CDCA and LCA and the glycine and taurine conjugates of LCA (g-LCA, t-LCA) were able to bind covalently with naked DNA in vitro without intervention of any catalyst.	Glycine	90-97	clathrin light chain A	Homo sapiens	124-127
7520097-3	1994	Conserved within this variable region is the sequence Arg-Gly-Asp (RGD), which, in the Ad2 penton base, binds to integrins in the target cell membrane, enhancing the rate or the efficiency of infection.	Glycine	58-61	apolipoprotein E	Homo sapiens	87-90
8075134-0	1994	Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR).	Glycine	24-31	solute carrier family 6 member 9	Homo sapiens	49-55
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	184-187
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	202-205
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	202-205
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	202-205
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	202-205
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	237-241
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	145-152	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	184-187
8049077-3	1994	ACE activity was significantly more abundant in the membrane-rich fraction than in the soluble cytosolic fraction of nasal mucosal extracts (74.18 +/- 24.50 versus 3.99 +/- 1.83 pmol/min/mg protein, respectively, P &lt; 0.01 by an enkephalin degradation assay; 89.16 +/- 16.17 versus 2.30 +/- 0.89 mU/mg protein, P &lt; 0.01 by colorimetric assessment of Bz-Gly-Gly-Gly degradation).	Glycine	358-361	angiotensin I converting enzyme	Homo sapiens	0-3
7949246-2	1994	We prepared three peptides derived from the type III connecting segment domain (IIICS) of fibronectin: Glu-Ile-Leu-Asp-Val (EILDV), Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr (EILDVPST), Arg-Glu-Asp-Val (REDV), and a laminin-related peptide, Tyr-Ile-Gly-Ser-Arg (YIGSR).	Glycine	239-242	fibronectin 1	Homo sapiens	90-101
7518445-1	1994	PAC1 is an IgM kappa murine monoclonal antibody that, like the Arg-Gly-Asp-containing ligand fibrinogen, binds to integrin alpha IIb beta 3 only on activated platelets.	Glycine	67-70	fibrinogen beta chain	Homo sapiens	93-103
7516705-5	1994	At saturating glycine concentrations, an average of 70% of the whole-cell current amplitude was associated with form A alpha and 30% with A beta.	Glycine	14-21	histocompatibility 2, class II antigen A, alpha	Mus musculus	117-124
7518462-3	1994	On an 11.5-kDa fragment of fibronectin that included the Arg-Gly-Asp (RGD) sequence, but not the synergy site, binding was reduced 50-fold.	Glycine	61-64	fibronectin 1	Homo sapiens	27-38
8034598-4	1994	We report here that the glycine/arginine-rich domains of GAR1, which are shared by several other nucleolar proteins, are neither sufficient nor required for the steady-state accumulation of the fusion protein in the nucleolus.	Glycine	24-31	H/ACA snoRNP pseudouridylase subunit GAR1	Saccharomyces cerevisiae S288C	57-61
7518829-3	1994	Other mutations, such as the relatively common glycine--&gt;aspartic acid replacement at CFTR position 551 (G551D) appear to be normally processed, and therefore must cause disease through some other mechanism.	Glycine	47-54	CF transmembrane conductance regulator	Homo sapiens	89-93
8023844-5	1994	The generation of DRB1*08042 (Val-86) from DRB1*0802 (Gly-86) in the Cayapa, by a different mechanism than the (GT--&gt;TG) change in the creation of DRB1*08041 (Val-86) from DRB1*0802 in Africa, implicates selection in the convergent evolution of position 86 DR beta variants.	Glycine	54-57	major histocompatibility complex, class II, DR beta 1	Homo sapiens	18-22
8023844-5	1994	The generation of DRB1*08042 (Val-86) from DRB1*0802 (Gly-86) in the Cayapa, by a different mechanism than the (GT--&gt;TG) change in the creation of DRB1*08041 (Val-86) from DRB1*0802 in Africa, implicates selection in the convergent evolution of position 86 DR beta variants.	Glycine	54-57	major histocompatibility complex, class II, DR beta 1	Homo sapiens	43-47
8023844-5	1994	The generation of DRB1*08042 (Val-86) from DRB1*0802 (Gly-86) in the Cayapa, by a different mechanism than the (GT--&gt;TG) change in the creation of DRB1*08041 (Val-86) from DRB1*0802 in Africa, implicates selection in the convergent evolution of position 86 DR beta variants.	Glycine	54-57	major histocompatibility complex, class II, DR beta 1	Homo sapiens	43-47
8023844-5	1994	The generation of DRB1*08042 (Val-86) from DRB1*0802 (Gly-86) in the Cayapa, by a different mechanism than the (GT--&gt;TG) change in the creation of DRB1*08041 (Val-86) from DRB1*0802 in Africa, implicates selection in the convergent evolution of position 86 DR beta variants.	Glycine	54-57	major histocompatibility complex, class II, DR beta 1	Homo sapiens	43-47
7982287-9	1994	CER by concomitant infusion of a subpressor dose of angiotensin II (AII) attenuated the progressive reduction of GLU release (87 +/- 4%, P &lt; 0.05 compared with NTG group), whereas GLY release was not affected (106 +/- 5%, NS compared with NTG group).	Glycine	183-186	angiotensinogen	Rattus norvegicus	52-66
7982287-9	1994	CER by concomitant infusion of a subpressor dose of angiotensin II (AII) attenuated the progressive reduction of GLU release (87 +/- 4%, P &lt; 0.05 compared with NTG group), whereas GLY release was not affected (106 +/- 5%, NS compared with NTG group).	Glycine	183-186	angiotensinogen	Rattus norvegicus	68-71
7812043-3	1994	To examine these possibilities, we have mutated Pro-1003 of the EGF receptor to a Gly residue and have analyzed the effect of this mutation on EGF-stimulated signaling.	Glycine	82-85	epidermal growth factor receptor	Homo sapiens	64-76
7516705-11	1994	In the presence of 100 microM glycine, the apparent dissociation constant for the inhibitor picrotoxinin from receptor form A alpha was 80 microM, and that from A beta was 460 microM.	Glycine	30-37	histocompatibility 2, class II antigen A, alpha	Mus musculus	124-131
8004673-4	1994	We have characterized patient-specific DHP receptor mutations in 11 probands of 33 independent hypoKPP kindreds that occur at one of two adjacent nucleotides within the same codon and predict substitution of a highly conserved arginine in the S4 segment of domain 4 with either histidine or glycine.	Glycine	291-298	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	39-51
7516705-15	1994	In the case of one receptor form (A alpha), the chemical mechanism and its constants led to two measurements that could be assessed by an independent method, the single-channel current-recording technique: (i) the fraction of receptor channels open at a given glycine concentration (ALn)o and (ii) the rate coefficient for desensitization.	Glycine	260-267	histocompatibility 2, class II antigen A, alpha	Mus musculus	34-41
7951134-2	1994	Four stable products were identified having exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic group(s) on insulin at the i) Gly(A1), ii) Gly(A1) and Phe(B1), iii) Gly(A1) and Lys(B29), and iv) Gly(A1), Phe(B1) and Lys(B29) sites, together with four labile products produced by the reaction of ETPA with the non-amino groups of the stable products.	Glycine	115-118	insulin	Homo sapiens	97-104
8206990-10	1994	Changing the P2 residue Phe353--&gt;Gly generated a mutant with a reactive site like antithrombin which was better at inhibiting thrombin or urokinase, but was much less active with APC or trypsin.	Glycine	36-39	coagulation factor II, thrombin	Homo sapiens	89-97
8206991-1	1994	The Src family consists of nine related tyrosine protein kinases with a common domain structure, including a myristylated N-terminal glycine residue.	Glycine	133-140	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	4-7
8206978-2	1994	We have shown previously that the lipoyltransferase activities locate in mitochondria using apoH-protein of the glycine cleavage system as an acceptor of the lipoyl group (Fujiwara, K., Okamura-Ikeda, K., and Motokawa, Y.	Glycine	112-119	apolipoprotein H	Bos taurus	92-96
7951134-2	1994	Four stable products were identified having exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic group(s) on insulin at the i) Gly(A1), ii) Gly(A1) and Phe(B1), iii) Gly(A1) and Lys(B29), and iv) Gly(A1), Phe(B1) and Lys(B29) sites, together with four labile products produced by the reaction of ETPA with the non-amino groups of the stable products.	Glycine	128-131	insulin	Homo sapiens	97-104
7951134-2	1994	Four stable products were identified having exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic group(s) on insulin at the i) Gly(A1), ii) Gly(A1) and Phe(B1), iii) Gly(A1) and Lys(B29), and iv) Gly(A1), Phe(B1) and Lys(B29) sites, together with four labile products produced by the reaction of ETPA with the non-amino groups of the stable products.	Glycine	128-131	insulin	Homo sapiens	97-104
7951134-2	1994	Four stable products were identified having exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic group(s) on insulin at the i) Gly(A1), ii) Gly(A1) and Phe(B1), iii) Gly(A1) and Lys(B29), and iv) Gly(A1), Phe(B1) and Lys(B29) sites, together with four labile products produced by the reaction of ETPA with the non-amino groups of the stable products.	Glycine	128-131	insulin	Homo sapiens	97-104
8011339-2	1994	Site-directed mutagenesis of the NMDAR1 (NR1) subunit revealed that aromatic residues at positions 390, 392, and 466 are crucial determinants of glycine binding.	Glycine	145-152	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	33-39
8075622-9	1994	Interpreting this localisation together with information from the literature, the following functions are suggested during resorption: Osteocalcin may act as a chemoattractant for osteoclasts, while both osteopontin and bone sialoprotein may facilitate the binding of osteoclasts via the arg-gly-asp motif.	Glycine	292-295	bone gamma-carboxyglutamate protein	Homo sapiens	135-146
8187090-5	1994	Another case showed a CGA (Arg) to GGA (Gly) mutation in codon 201, which might be a polymorphic change, and two other mutations resulting in no amino acid change.	Glycine	40-43	chromogranin A	Homo sapiens	22-25
8011339-2	1994	Site-directed mutagenesis of the NMDAR1 (NR1) subunit revealed that aromatic residues at positions 390, 392, and 466 are crucial determinants of glycine binding.	Glycine	145-152	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	41-44
8182055-0	1994	A glycine to aspartic acid change in the MoCo domain of nitrate reductase reduces both activity and phosphorylation levels in Arabidopsis.	Glycine	2-9	nitrate reductase 1	Arabidopsis thaliana	56-73
8183370-7	1994	Substitution of Gly 145 in BH1 domain or Trp 188 in BH2 domain completely abrogated Bcl-2"s death-repressor activity in interleukin-3 deprivation, gamma-irradiation and glucocorticoid-induced apoptosis.	Glycine	16-19	BCL2 apoptosis regulator	Homo sapiens	84-89
8182063-1	1994	We have characterized a GluR3 mutant (sGluR3) which has a 33-amino acid deletion in its second cytoplasmic loop (deficit from Tyr-715 to Gly-747 of GluR3-flop).	Glycine	137-140	glutamate receptor, ionotropic, AMPA 3 L homeolog	Xenopus laevis	24-29
8182063-1	1994	We have characterized a GluR3 mutant (sGluR3) which has a 33-amino acid deletion in its second cytoplasmic loop (deficit from Tyr-715 to Gly-747 of GluR3-flop).	Glycine	137-140	glutamate receptor, ionotropic, AMPA 3 L homeolog	Xenopus laevis	39-44
7910376-4	1994	Here we report that, by contrast, the ced-9(n1950) gain-of-function mutation affects the open reading frame of ced-9 and results in a glycine-to-glutamate substitution in a region highly conserved among all ced-9/bcl-2 family members.	Glycine	134-141	Apoptosis regulator ced-9	Caenorhabditis elegans	38-43
7910376-4	1994	Here we report that, by contrast, the ced-9(n1950) gain-of-function mutation affects the open reading frame of ced-9 and results in a glycine-to-glutamate substitution in a region highly conserved among all ced-9/bcl-2 family members.	Glycine	134-141	Apoptosis regulator ced-9	Caenorhabditis elegans	111-116
7910376-4	1994	Here we report that, by contrast, the ced-9(n1950) gain-of-function mutation affects the open reading frame of ced-9 and results in a glycine-to-glutamate substitution in a region highly conserved among all ced-9/bcl-2 family members.	Glycine	134-141	Apoptosis regulator ced-9	Caenorhabditis elegans	111-116
7910376-4	1994	Here we report that, by contrast, the ced-9(n1950) gain-of-function mutation affects the open reading frame of ced-9 and results in a glycine-to-glutamate substitution in a region highly conserved among all ced-9/bcl-2 family members.	Glycine	134-141	BCL2 apoptosis regulator	Homo sapiens	213-218
7910376-5	1994	We conclude that this glycine has an important function in ced-9 regulation, and we suggest that alteration of this glycine in other members of the ced-9/bcl-2 family might lead to oncogenic activation.	Glycine	22-29	Apoptosis regulator ced-9	Caenorhabditis elegans	59-64
7910376-5	1994	We conclude that this glycine has an important function in ced-9 regulation, and we suggest that alteration of this glycine in other members of the ced-9/bcl-2 family might lead to oncogenic activation.	Glycine	22-29	Apoptosis regulator ced-9	Caenorhabditis elegans	148-153
7910376-5	1994	We conclude that this glycine has an important function in ced-9 regulation, and we suggest that alteration of this glycine in other members of the ced-9/bcl-2 family might lead to oncogenic activation.	Glycine	22-29	BCL2 apoptosis regulator	Homo sapiens	154-159
7910376-5	1994	We conclude that this glycine has an important function in ced-9 regulation, and we suggest that alteration of this glycine in other members of the ced-9/bcl-2 family might lead to oncogenic activation.	Glycine	116-123	Apoptosis regulator ced-9	Caenorhabditis elegans	148-153
7910376-5	1994	We conclude that this glycine has an important function in ced-9 regulation, and we suggest that alteration of this glycine in other members of the ced-9/bcl-2 family might lead to oncogenic activation.	Glycine	116-123	BCL2 apoptosis regulator	Homo sapiens	154-159
8180198-4	1994	Only the replacement by serine--a natural substitute for this glycine residue in some forms of mercuric reductase, a related flavoprotein disulfide oxidoreductase--produced a mutant enzyme (G176S) that retained significant catalytic activity.	Glycine	62-69	mercuric reductase	Escherichia coli	95-113
8182055-8	1994	This glycine, at position 308 in the MoCo domain of NR, is completely conserved in all known eukaryotic NR sequences.	Glycine	5-12	nitrate reductase 1	Arabidopsis thaliana	52-54
8182055-8	1994	This glycine, at position 308 in the MoCo domain of NR, is completely conserved in all known eukaryotic NR sequences.	Glycine	5-12	nitrate reductase 1	Arabidopsis thaliana	104-106
8182055-9	1994	Thus, glycine 308 is required for normal activity and phosphorylation of NR, and substitution of this residue with aspartic acid disrupts both processes, most likely by altering the conformation of the NR MoCo domain.	Glycine	6-13	nitrate reductase 1	Arabidopsis thaliana	73-75
8170978-5	1994	The predicted amino acid composition is interesting in that approximately 45% of the PHAS-I protein is accounted for by only four amino acids--serine, threonine, proline, and glycine.	Glycine	175-182	eukaryotic translation initiation factor 4E binding protein 1	Rattus norvegicus	85-91
8183888-4	1994	Saturation mutagenesis was used to investigate the role played by two of these residues (Gly-439 and Ser-440 of the human glucocorticoid receptor) in receptor specificity.	Glycine	89-92	nuclear receptor subfamily 3 group C member 1	Homo sapiens	122-145
7520724-3	1994	These patients were demonstrated to possess point mutations resulting in glycine-->arginine substitutions within the triple helical domain of the alpha 1(I) or alpha 2(I) collagen polypeptide chain.	Glycine	73-80	collagen type I alpha 2 chain	Homo sapiens	146-179
7520724-6	1994	Both defects were informative in that they identified the regions of the alpha 1(I) and alpha 2(I) collagen chains in which the phenotypes associated with glycine-->arginine substitutions undergo a transition between lethal and nonlethal forms, thereby allowing a more reliable prognosis of disease severity.	Glycine	155-162	collagen type I alpha 2 chain	Homo sapiens	73-107
8088785-7	1994	Sequence analysis showed that NAGR1 is a glycine-, tryptophan-, and methionine-rich protein with no cysteine residues or glycosylation site.	Glycine	41-48	heterogeneous nuclear ribonucleoprotein M	Homo sapiens	30-35
8061610-15	1994	Inspection of the 3-dimensional structure of trypanosomal triosephosphate isomerase, which has a methionine at position 122, only increased the mystery of the effects of the Gly to Arg mutation in the human enzyme.	Glycine	174-177	triosephosphate isomerase 1	Homo sapiens	58-83
7512951-8	1994	These results unequivocally demonstrate that eNOS incorporates myristic acid via an amide linkage with the amino-terminal glycine of the enzyme as a co-translational modification.	Glycine	122-129	nitric oxide synthase 3	Bos taurus	45-49
8143877-0	1994	The actin binding site in the tail domain of Dictyostelium myosin IC (myoC) resides within the glycine- and proline-rich sequence (tail homology region 2).	Glycine	95-102	myosin IC	Homo sapiens	59-68
8157695-2	1994	Procollagen I was isolated from cultured skin fibroblasts from a proband who was homozygous for a mutation in the COL1A2 gene that substituted a serine codon for a glycine codon at position 661 of the alpha 2(I) chain.	Glycine	164-171	collagen type I alpha 2 chain	Homo sapiens	114-120
8163493-10	1994	These results suggest that ligand-mediated internalization of the human IGF-I is consistent with saturable interactions between the IGF-I receptor juxtamembrane region (glycine 940-tyrosine 957) and components of the endocytic apparatus.	Glycine	169-176	insulin like growth factor 1	Homo sapiens	72-77
7513610-6	1994	In cell adhesion assays, the 69-6-5 mAb was able to inhibit strongly in a dose-dependent manner arginine-glycine-aspartic acid-mediated adhesion of HT29-D4 cells to vitronectin, fibronectin, or ProNectin F but not to laminin or collagen.	Glycine	105-112	fibronectin 1	Homo sapiens	178-189
7511609-2	1994	Fibronectin (Fn) binding to the integrins alpha IIb beta 3 and alpha v beta 3 involves the Arg-Gly-Asp sequence.	Glycine	95-98	fibronectin 1	Homo sapiens	0-11
8143877-0	1994	The actin binding site in the tail domain of Dictyostelium myosin IC (myoC) resides within the glycine- and proline-rich sequence (tail homology region 2).	Glycine	95-102	myosin IC	Homo sapiens	70-74
8143877-3	1994	Here we show, using fusion proteins containing portions of the Dictyostelium myosin IC (myoC) tail domain and F-actin sedimentation assays, that the ability of the myoC tail to bind to actin resides entirely within the glycine- and proline-rich TH.2 domain.	Glycine	219-226	myosin IC	Homo sapiens	77-86
8143877-3	1994	Here we show, using fusion proteins containing portions of the Dictyostelium myosin IC (myoC) tail domain and F-actin sedimentation assays, that the ability of the myoC tail to bind to actin resides entirely within the glycine- and proline-rich TH.2 domain.	Glycine	219-226	myosin IC	Homo sapiens	164-168
8132653-5	1994	Mutagenesis of the double-disrupted, shm1 shm2 yeast yielded strains of a single complementation group that are auxotrophic for glycine.	Glycine	128-135	glycine hydroxymethyltransferase SHM1	Saccharomyces cerevisiae S288C	37-41
7923904-6	1994	Genotyping for the I/D polymorphism was performed by polymerase chain reaction and plasma DCP1 activity was measured by rate of hydrolysis of both [3H]-Hip-Gly-Gly and Hip-His-Leu.	Glycine	156-159	angiotensin I converting enzyme	Homo sapiens	90-94
7923904-6	1994	Genotyping for the I/D polymorphism was performed by polymerase chain reaction and plasma DCP1 activity was measured by rate of hydrolysis of both [3H]-Hip-Gly-Gly and Hip-His-Leu.	Glycine	160-163	angiotensin I converting enzyme	Homo sapiens	90-94
8139571-6	1994	Arg-1 or Arg-4 to Cys mutations in homology block A (HBA; consensus, 1-RXRRQ-5; in the amino non-Gly-X-Y domain) caused RRol phenotypes, while the same alteration at Arg-3 had no effect, indicating that Arg-3 is functionally different from Arg-1 and Arg-4.	Glycine	97-100	Delta-like protein	Caenorhabditis elegans	0-5
8132653-6	1994	Complementation of the glycine auxotrophy using a yeast genomic library retrieved the SHM1 and SHM2 genes and a third gene designated GLY1.	Glycine	23-30	glycine hydroxymethyltransferase SHM1	Saccharomyces cerevisiae S288C	86-90
8132653-6	1994	Complementation of the glycine auxotrophy using a yeast genomic library retrieved the SHM1 and SHM2 genes and a third gene designated GLY1.	Glycine	23-30	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	134-138
8132653-7	1994	Gene disruption studies demonstrated that inactivation of SHM1, SHM2, and GLY1 is required to yield yeast that are completely auxotrophic for glycine.	Glycine	142-149	glycine hydroxymethyltransferase SHM1	Saccharomyces cerevisiae S288C	58-62
8132653-7	1994	Gene disruption studies demonstrated that inactivation of SHM1, SHM2, and GLY1 is required to yield yeast that are completely auxotrophic for glycine.	Glycine	142-149	threonine aldolase GLY1	Saccharomyces cerevisiae S288C	74-78
7907326-0	1994	Functional consequences of glycine mutations in the predicted cytoplasmic loops of P-glycoprotein.	Glycine	27-34	ATP binding cassette subfamily B member 1	Homo sapiens	83-97
7907326-1	1994	Site-directed mutagenesis was used to investigate whether glycine residues in the predicted cytoplasmic loops play essential roles in the structure and function of human P-glycoprotein.	Glycine	58-65	ATP binding cassette subfamily B member 1	Homo sapiens	170-184
7907326-11	1994	These results demonstrate that glycines located in the cytoplasmic loops play important roles in structure and function of P-glycoprotein.	Glycine	31-39	ATP binding cassette subfamily B member 1	Homo sapiens	123-137
8156744-2	1994	The plasma lipoprotein profiles of eight members of a Dutch pedigree spanning three generations where two rare apolipoprotein E mutants, APOE*3(Cys-112--&gt;Arg; Arg-251--&gt;Gly) and APOE*2(Val-236--&gt;Glu), segregate were analysed to determine whether the APOE mutants were associated with dyslipidaemia.	Glycine	175-178	apolipoprotein E	Homo sapiens	111-127
8120035-8	1994	Furthermore, recombinant vWF with Gly or Ala at all three positions induces platelet aggregation in the presence of ristocetin and binds to platelet glycoprotein Ib, factor VIII, and collagen in a manner similar to wild-type recombinant vWF.	Glycine	34-37	von Willebrand factor	Homo sapiens	25-28
8120035-8	1994	Furthermore, recombinant vWF with Gly or Ala at all three positions induces platelet aggregation in the presence of ristocetin and binds to platelet glycoprotein Ib, factor VIII, and collagen in a manner similar to wild-type recombinant vWF.	Glycine	34-37	von Willebrand factor	Homo sapiens	237-240
7923409-2	1994	This strain, VC32, carries a mutation in the mitochondrial COX2 gene which converts a conserved glycine residue to arginine.	Glycine	96-103	cytochrome c oxidase subunit 2	Saccharomyces cerevisiae S288C	59-63
8156744-4	1994	The proband, a 51-year-old Caucasian male, was a carrier of APOE*3(Cys-112--&gt;Arg; Arg-251--&gt;Gly) and his spouse was a carrier of APOE*2(Val-236--&gt;Glu).	Glycine	98-101	apolipoprotein E	Homo sapiens	60-66
8156744-8	1994	The plasma triacylglycerol concentration was moderately increased in a sister, who was a carrier of APOE*3(Cys-112--&gt;Arg; Arg-251--&gt;Gly), and in the son, who was a compound heterozygote for both mutant APOE alleles.	Glycine	138-141	apolipoprotein E	Homo sapiens	100-104
8107847-6	1994	We show here that the mutation Gly 90--&gt;Asp (G90D) in the second transmembrane segment of rhodopsin, which causes congenital night blindness, also constitutively activates opsin.	Glycine	31-34	rhodopsin	Homo sapiens	93-102
8133057-9	1994	These results indicate that chemotaxis of PMNs in response to TGF-beta isoforms is mediated by the interaction of the Arg-gly-Asp-ser sequence in the CBD of Fn with an integrin on the PMN cell surface, primarily the VLA-5 integrin.	Glycine	122-125	transforming growth factor beta 1	Homo sapiens	62-70
8133057-9	1994	These results indicate that chemotaxis of PMNs in response to TGF-beta isoforms is mediated by the interaction of the Arg-gly-Asp-ser sequence in the CBD of Fn with an integrin on the PMN cell surface, primarily the VLA-5 integrin.	Glycine	122-125	integrin subunit alpha 5	Homo sapiens	216-221
8208902-4	1994	Sequencing of the apoAI gene demonstrated that the proband was a heterozygote for a single base substitution in exon 3, changing codon 26 from GGC(Gly) to CGC(Arg).	Glycine	147-150	apolipoprotein A1	Homo sapiens	18-23
8289785-5	1994	Both Gly and Ala, substituted at PET54 position 244, disrupted the two-hybrid interactions with PET122 and PET494.	Glycine	5-8	Pet54p	Saccharomyces cerevisiae S288C	33-38
7508443-8	1994	Mutagenesis of a homologous Gly within the integrin alpha subunit alpha v also resulted in the failure to express alpha v beta 3 on the cell surface.	Glycine	28-31	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3	Homo sapiens	114-128
8159808-0	1994	Glycine-extended post-translational processing intermediates of gastrin and cholecystokinin in the gut.	Glycine	0-7	cholecystokinin	Homo sapiens	76-91
7695484-7	1994	Thrombospondin (TSP), an anti-adhesive protein, was capable of inhibiting the spreading of the cells both after 1 h and 24 h. However, type V collagen treated with TSP inhibited the cell spreading after 1 h, but not after 24 h. The attachment and spreading of the cells on type V collagen were little affected by an anti-TSP antibody and the synthetic peptide GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro), which significantly inhibited the attachment and spreading of the cells on TSP.	Glycine	368-371	thrombospondin 1	Homo sapiens	16-19
8309590-6	1994	Molecular genetic studies showed a missense mutation (Gly-->Ser, codon 41) in exon 2 of the Cu/Zn superoxide dismutase gene (SOD1) on chromosome 21 in the available affected member and in 45% of the at-risk subjects of the pedigree.	Glycine	54-57	superoxide dismutase 1	Homo sapiens	125-129
8300630-3	1994	Chinese hamster ovary clones which were transfected with Pro385--&gt;Ile and Pro385--&gt;glycine mutations of GLUT1 were shown, by Western blotting and cell surface carbohydrate labelling, to have expression levels which were comparable with the wild type.	Glycine	89-96	solute carrier family 2, facilitated glucose transporter member 1	Cricetulus griseus	110-115
8276845-14	1994	The VCS-beta 1 cDNA codes for a proline-rich protein precursor named PR-V beta 1 (148 amino acids, 39.2% proline, 10.8% glycine) and characterized by a secretory signal-peptide and three repeats of a unit rich in proline residues surrounded by two clusters of potential endoprotease cleavage sites.	Glycine	120-127	submaxillary gland androgen regulated protein 3A	Rattus norvegicus	4-14
8276845-14	1994	The VCS-beta 1 cDNA codes for a proline-rich protein precursor named PR-V beta 1 (148 amino acids, 39.2% proline, 10.8% glycine) and characterized by a secretory signal-peptide and three repeats of a unit rich in proline residues surrounded by two clusters of potential endoprotease cleavage sites.	Glycine	120-127	submaxillary gland androgen regulated protein 3A	Rattus norvegicus	69-80
7695484-7	1994	Thrombospondin (TSP), an anti-adhesive protein, was capable of inhibiting the spreading of the cells both after 1 h and 24 h. However, type V collagen treated with TSP inhibited the cell spreading after 1 h, but not after 24 h. The attachment and spreading of the cells on type V collagen were little affected by an anti-TSP antibody and the synthetic peptide GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro), which significantly inhibited the attachment and spreading of the cells on TSP.	Glycine	368-371	thrombospondin 1	Homo sapiens	0-14
7695484-7	1994	Thrombospondin (TSP), an anti-adhesive protein, was capable of inhibiting the spreading of the cells both after 1 h and 24 h. However, type V collagen treated with TSP inhibited the cell spreading after 1 h, but not after 24 h. The attachment and spreading of the cells on type V collagen were little affected by an anti-TSP antibody and the synthetic peptide GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro), which significantly inhibited the attachment and spreading of the cells on TSP.	Glycine	368-371	thrombospondin 1	Homo sapiens	164-167
7695484-7	1994	Thrombospondin (TSP), an anti-adhesive protein, was capable of inhibiting the spreading of the cells both after 1 h and 24 h. However, type V collagen treated with TSP inhibited the cell spreading after 1 h, but not after 24 h. The attachment and spreading of the cells on type V collagen were little affected by an anti-TSP antibody and the synthetic peptide GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro), which significantly inhibited the attachment and spreading of the cells on TSP.	Glycine	368-371	thrombospondin 1	Homo sapiens	164-167
7695484-7	1994	Thrombospondin (TSP), an anti-adhesive protein, was capable of inhibiting the spreading of the cells both after 1 h and 24 h. However, type V collagen treated with TSP inhibited the cell spreading after 1 h, but not after 24 h. The attachment and spreading of the cells on type V collagen were little affected by an anti-TSP antibody and the synthetic peptide GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro), which significantly inhibited the attachment and spreading of the cells on TSP.	Glycine	368-371	thrombospondin 1	Homo sapiens	164-167
8181961-7	1994	Also, DRB1 alleles that are negatively associated with MS all encode a Gly at position 86, suggesting that the residue at position 86 may be critical in conferring susceptibility and protection to MS.	Glycine	71-74	major histocompatibility complex, class II, DR beta 1	Homo sapiens	6-10
8019561-4	1994	Direct sequencing of the PCR products for exon 19 revealed a single base mutation that converted the codon of -GGT- for glycine at alpha 1-247 to -AGT-, a codon for serine.	Glycine	120-127	angiotensinogen	Homo sapiens	147-150
7764512-3	1994	The cystatin consists of 111 amino acid residues with two disulfide linkages formed between 66-75 and 89-109, and has 43% identical sequences with chicken egg-white cystatin with consensus sequences of reactive sites, Gly(4), Gln-X-Val-X-Gly (48-52), and Ile(Val)-Pro-Trp (96-98).	Glycine	218-221	cystatin C	Gallus gallus	4-12
18472928-0	1994	A novel Mutein of TNFalpha Containing the Arg-Gly-Asp Sequence Shows Reduced Toxicity in Intestine.	Glycine	46-49	tumor necrosis factor	Homo sapiens	18-26
8263031-10	1994	Adding the synthetic peptide, arg-gly-asp-ser (RGDS) to the medium, blocked migration on fibronectin-coated implants but had no effect on implants coated with type IV, suggesting that migration on type IV involves different cell surface receptors than those mediating migration over fibronectin.	Glycine	34-37	fibronectin 1	Homo sapiens	89-100
8263031-10	1994	Adding the synthetic peptide, arg-gly-asp-ser (RGDS) to the medium, blocked migration on fibronectin-coated implants but had no effect on implants coated with type IV, suggesting that migration on type IV involves different cell surface receptors than those mediating migration over fibronectin.	Glycine	34-37	fibronectin 1	Homo sapiens	283-294
18472928-6	1994	These results suggest that the Arg-Gly-Asp sequence introduced into the TNFalpha molecule abrogates the side effect of this cytokine such as tissue injury or shock, and that F4168 could be useful for systemic therapy.	Glycine	35-38	tumor necrosis factor	Homo sapiens	72-80
8253805-0	1993	Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase.	Glycine	127-134	galectin 3	Rattus norvegicus	49-60
8262937-2	1993	Single turnover and equilibrium binding measurements on the interaction of Gly-12 and Pro-12 Ras.GTP with the catalytic domains of the GTPase-activating proteins, p120-GAP and neurofibromin, have been made utilizing fluorescent 2"(3")O-(N-methylanthraniloyl)-nucleotides.	Glycine	75-78	neurofibromin 1	Homo sapiens	176-189
8262937-5	1993	Both p120-GAP and neurofibromin increased the rate constant of the GTP hydrolysis step of Pro-12 Ras, but the maximal activation at 30 degrees C was 120-fold and 560-fold, as compared with 70,000- and 52,000-fold, with Gly-12 Ras.	Glycine	219-222	neurofibromin 1	Homo sapiens	18-31
8262937-6	1993	The affinity with which p120-GAP and neurofibromin binds to either Gly-12 or Pro-12 Ras protein was decreased dramatically by increasing ionic strength caused by addition of NaCl.	Glycine	67-70	neurofibromin 1	Homo sapiens	37-50
7903170-5	1993	Sequence analysis of these aberrant peptides and isolated A alpha chains of the patient"s fibrinogen showed that Glu at position 11 of the abnormal A alpha chain had been replaced by Gly.	Glycine	183-186	fibrinogen beta chain	Homo sapiens	90-100
8136018-6	1993	Thrombin Quick II is a dysfunctional thrombin mutant with a Gly 226--&gt;Val substitution in the substrate specificity pocket.	Glycine	60-63	coagulation factor II, thrombin	Homo sapiens	0-8
7903250-6	1993	Through genetic remodeling techniques, we now show that ARM-Gly505 in ANF-RGC and the corresponding ARM-Gly499 in CNP-RGC are critical for ANF and CNP signaling, and other ARM-Gly residues have minimal effect in the respective signaling processes.	Glycine	60-63	natriuretic peptide A	Homo sapiens	70-73
7903250-6	1993	Through genetic remodeling techniques, we now show that ARM-Gly505 in ANF-RGC and the corresponding ARM-Gly499 in CNP-RGC are critical for ANF and CNP signaling, and other ARM-Gly residues have minimal effect in the respective signaling processes.	Glycine	60-63	natriuretic peptide A	Homo sapiens	139-142
8245119-2	1993	NSR1 has three regions: an acidic/serine-rich NH2 terminus, two RNA recognition motifs, and a glycine/arginine-rich COOH terminus.	Glycine	94-101	scavenger receptor class F member 2	Homo sapiens	0-4
8136018-6	1993	Thrombin Quick II is a dysfunctional thrombin mutant with a Gly 226--&gt;Val substitution in the substrate specificity pocket.	Glycine	60-63	coagulation factor II, thrombin	Homo sapiens	37-45
7693712-0	1993	Two additional cases of osteogenesis imperfecta with substitutions for glycine in the alpha 2(I) collagen chain.	Glycine	71-78	collagen type I alpha 2 chain	Homo sapiens	86-105
8226878-5	1993	Most significantly a highly repetitive region (19 repeat units of 20 residues each), not found in either human or rat, enlarges one of the characteristic serine-glycine containing regions (designated CS-2) while the other serine-glycine containing domain (designated CS-1) is approximately one-fourth the length of the mammalian CS-1.	Glycine	161-168	catalase	Rattus norvegicus	267-271
7504274-4	1993	The identified library epitopes shared the consensus sequence Pro-(Pro/Ser)-Gly-His-(Tyr/Phe)-Lys, corresponding to two continuous protein sequences of bFGF: Pro-Pro-Gly-His-Phe-Lys and Arg-Thr-Gly-Gln-Tyr-Lys at amino acids 13-18 and 120-125 of bFGF, respectively.	Glycine	76-79	fibroblast growth factor 2	Homo sapiens	152-156
8402654-5	1993	This mutation resulted in a glycine to aspartic acid substitution within the putative trans-activation domain of WT1, converting the encoded protein from a transcriptional repressor to an activator of its target DNA sequence.	Glycine	28-35	WT1 transcription factor	Homo sapiens	113-116
8221663-3	1993	Further analysis of 14 ES and related primary tumors showed mutations of the p53 gene in only two: one base insertion of CCG--&gt;CCCG at codon 152 in one and a missense mutation of GGC (Gly)--&gt;GTC (Val) at codon 154 in the other.	Glycine	187-190	tumor protein p53	Homo sapiens	77-80
8118430-1	1993	The effect of a synthetic C-terminal peptide sequence of human growth hormone, Leu-Arg-Ile-Val-Gln-Cys-Arg-Val-Ser-Glu-Gly-Ser-Cys-Gly-Phe (hGH 177-191) on glucose transport in adipocytes isolated from genetically-obese Zucker rats was investigated.	Glycine	119-122	growth hormone 1	Homo sapiens	63-77
7509429-0	1993	Immunohistochemical monitoring of the effect of a synthetic fibronectin-like peptide (Arg-Gly-Asp) on the age-related changes in the isolated human corneoscleral tissue of glaucomatous eyes.	Glycine	90-93	fibronectin 1	Homo sapiens	60-71
7509429-5	1993	The active amino acid sequence in fibronectin is an arginine-glycine-aspartic acid tripeptide (Arg-Gly-Asp) and it was shown that the synthetic Arg-Gly-Asp peptide specifically inhibited the adhesive function of fibronectin in trabecular meshwork samples when incubated for 30 min at a concentration of 1-2 mg/ml.	Glycine	61-68	fibronectin 1	Homo sapiens	34-45
7509429-5	1993	The active amino acid sequence in fibronectin is an arginine-glycine-aspartic acid tripeptide (Arg-Gly-Asp) and it was shown that the synthetic Arg-Gly-Asp peptide specifically inhibited the adhesive function of fibronectin in trabecular meshwork samples when incubated for 30 min at a concentration of 1-2 mg/ml.	Glycine	61-68	fibronectin 1	Homo sapiens	212-223
7903167-4	1993	By performing glycine concentration-response curves and comparing EC50s, it was possible to show that the NR1 + NR2A + NR2C receptor preferentially co-assembled when all three subunit cDNAs were present.	Glycine	14-21	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	106-109
8251940-0	1993	In vitro aging of calmodulin generates isoaspartate at multiple Asn-Gly and Asp-Gly sites in calcium-binding domains II, III, and IV.	Glycine	68-71	calmodulin	Bos taurus	18-28
8251940-0	1993	In vitro aging of calmodulin generates isoaspartate at multiple Asn-Gly and Asp-Gly sites in calcium-binding domains II, III, and IV.	Glycine	80-83	calmodulin	Bos taurus	18-28
7903167-4	1993	By performing glycine concentration-response curves and comparing EC50s, it was possible to show that the NR1 + NR2A + NR2C receptor preferentially co-assembled when all three subunit cDNAs were present.	Glycine	14-21	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	112-116
7903167-5	1993	This receptor had an affinity for glycine intermediate between that of NR1 + NR2A and NR1 + NR2C, but a similar Hill coefficient.	Glycine	34-41	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	71-74
8401225-8	1993	The double mutant, Ile-6--&gt;Gly/Tyr-13--&gt;Gly, was reduced in potency to &lt; 0.2%, which correlated with a correspondingly low binding affinity for neutrophil C5a receptors.	Glycine	30-33	complement C5a receptor 1	Homo sapiens	164-167
8373786-2	1993	Intact fibronectin molecule and its 120 kDa fragment, containing the Arg-Gly-Asp (RGD) sequence motif, as well as a synthetic RGD-containing peptide Peptite 2000 all bound progenitor cells.	Glycine	73-76	fibronectin 1	Homo sapiens	7-18
8373786-4	1993	The binding of intact fibronectin and its 120 kDa fragment was inhibited in a dose-dependent fashion with increasing concentration of RGD-containing Gly-Arg-Gly-Asp-Ser peptide, but not with Gly-Arg-Gly-Glu-Ser control peptide that does not contain the RGD sequence motif.	Glycine	149-152	fibronectin 1	Homo sapiens	22-33
8373786-4	1993	The binding of intact fibronectin and its 120 kDa fragment was inhibited in a dose-dependent fashion with increasing concentration of RGD-containing Gly-Arg-Gly-Asp-Ser peptide, but not with Gly-Arg-Gly-Glu-Ser control peptide that does not contain the RGD sequence motif.	Glycine	157-160	fibronectin 1	Homo sapiens	22-33
8373786-4	1993	The binding of intact fibronectin and its 120 kDa fragment was inhibited in a dose-dependent fashion with increasing concentration of RGD-containing Gly-Arg-Gly-Asp-Ser peptide, but not with Gly-Arg-Gly-Glu-Ser control peptide that does not contain the RGD sequence motif.	Glycine	157-160	fibronectin 1	Homo sapiens	22-33
8373786-4	1993	The binding of intact fibronectin and its 120 kDa fragment was inhibited in a dose-dependent fashion with increasing concentration of RGD-containing Gly-Arg-Gly-Asp-Ser peptide, but not with Gly-Arg-Gly-Glu-Ser control peptide that does not contain the RGD sequence motif.	Glycine	157-160	fibronectin 1	Homo sapiens	22-33
8103491-4	1993	The predicted Xlim-3 protein contains two copies of the LIM domain, a homeodomain, and a C-terminal region rich in proline, glycine, and serine.	Glycine	124-131	LIM homeobox 3 L homeolog	Xenopus laevis	14-20
8411726-1	1993	Recently, three different mutations have been found at codon 717 of the amyloid precursor protein (APP) gene, changing the native valine to isoleucine, phenylalanine and glycine in some familial Alzheimer"s disease (FAD) kindreds.	Glycine	170-177	amyloid beta precursor protein	Homo sapiens	72-97
8400877-5	1993	The hy8-3 mutant that expresses wild-type levels of photochemically active phytochrome A has a glycine-to-glutamate missense mutation at residue 727 in the C-terminal domain of the phyA sequence.	Glycine	95-102	phytochrome A	Arabidopsis thaliana	4-7
8400877-5	1993	The hy8-3 mutant that expresses wild-type levels of photochemically active phytochrome A has a glycine-to-glutamate missense mutation at residue 727 in the C-terminal domain of the phyA sequence.	Glycine	95-102	phytochrome A	Arabidopsis thaliana	75-88
8400877-7	1993	This result indicates that glycine-727, which is invariant in all sequenced phytochromes, has a function important to the regulatory activity of phytochrome A but not to photoperception.	Glycine	27-34	phytochrome A	Arabidopsis thaliana	145-158
8401225-3	1993	We have examined the N-terminal region (NTR) of human C5a by replacing selected residues in the NTR with glycine via site-directed mutagenesis.	Glycine	105-112	complement C5a receptor 1	Homo sapiens	54-57
8401225-8	1993	The double mutant, Ile-6--&gt;Gly/Tyr-13--&gt;Gly, was reduced in potency to &lt; 0.2%, which correlated with a correspondingly low binding affinity for neutrophil C5a receptors.	Glycine	46-49	complement C5a receptor 1	Homo sapiens	164-167
8393341-4	1993	NPK forms a regular amphipathic alpha-helical structure from Asp 3, terminating at Gly 18.	Glycine	83-86	tachykinin precursor 1	Homo sapiens	0-3
8259537-6	1993	Thus, the hypothetical two-pronged socket-like structure consisting of the alpha-amino group of the amino-terminal Gly and the guanidino group of an Arg at position 3 of the normal fibrin alpha-chain seems to be restored considerably in the mutant fibrin alpha-chain at low ionic strengths and pH"s, despite the replacement of the amino-terminal Gly by another aliphatic amino acid Val.	Glycine	115-118	Fc gamma receptor and transporter	Homo sapiens	188-199
8259537-6	1993	Thus, the hypothetical two-pronged socket-like structure consisting of the alpha-amino group of the amino-terminal Gly and the guanidino group of an Arg at position 3 of the normal fibrin alpha-chain seems to be restored considerably in the mutant fibrin alpha-chain at low ionic strengths and pH"s, despite the replacement of the amino-terminal Gly by another aliphatic amino acid Val.	Glycine	346-349	Fc gamma receptor and transporter	Homo sapiens	188-199
8349606-5	1993	Fluorescence-detected melting curves of Glu-Gly-Arg-cmk-urokinase indicated that unfolding/refolding at pH 4.5 is characterized by dramatic hysteresis; the cooling curves fell close to those obtained upon heating or cooling of the uninhibited enzyme.	Glycine	44-47	C-X-C motif chemokine ligand 9	Homo sapiens	52-55
8241567-9	1993	dpy-10(cn64), a dominant temperature-sensitive DLRol allele, creates an Arg-to-Cys substitution in the amino non-Gly-X-Y portion of the protein.	Glycine	113-116	Uncharacterized protein	Caenorhabditis elegans	0-6
8241567-11	1993	dpy-10(cg36) (DRLol) creates a nonsense codon near the end of the Gly-X-Y region.	Glycine	66-69	Uncharacterized protein	Caenorhabditis elegans	0-6
8100229-2	1993	This ligand has been named GlyCAM 1 (Gly-cosylation-dependent Cell Adhesion Molecule 1) because its adhesive interactions with the L selectin lectin domain require that the GlyCAM 1 polypeptide chain be appropriately modified with carbohydrates.	Glycine	27-30	cell adhesion molecule 1	Mus musculus	62-86
8333874-5	1993	The proposed CCK "B-conformation" has a distorted beta-III turn at the C-terminal Gly-Trp-Met-Asp fragment, the Phe33 residue and the C-terminal amide being directed outward from the turn.	Glycine	82-85	cholecystokinin B receptor	Homo sapiens	13-19
8343513-2	1993	Analogues include those in which ArgB22 of des-octapeptide(B23-B30)-insulin is extended by one to three residues of glycine prior to termination in Phe-NH2, by one to five residues of glycine prior to termination in Phe-Phe-NH2, or by an additional residue of glycine prior to termination in more extended sequences derived from insulin or [GlyB24]insulin.	Glycine	116-123	insulin	Homo sapiens	68-75
8343513-2	1993	Analogues include those in which ArgB22 of des-octapeptide(B23-B30)-insulin is extended by one to three residues of glycine prior to termination in Phe-NH2, by one to five residues of glycine prior to termination in Phe-Phe-NH2, or by an additional residue of glycine prior to termination in more extended sequences derived from insulin or [GlyB24]insulin.	Glycine	184-191	insulin	Homo sapiens	68-75
8343513-2	1993	Analogues include those in which ArgB22 of des-octapeptide(B23-B30)-insulin is extended by one to three residues of glycine prior to termination in Phe-NH2, by one to five residues of glycine prior to termination in Phe-Phe-NH2, or by an additional residue of glycine prior to termination in more extended sequences derived from insulin or [GlyB24]insulin.	Glycine	184-191	insulin	Homo sapiens	68-75
8334132-2	1993	Using site-directed mutagenesis, we have substituted the corresponding reactive Cys278 in the chicken cardiac mitochondrial creatine kinase (Mib-CK) with either glycine, serine, alanine, asparagine, or aspartate.	Glycine	161-168	creatine kinase, mitochondrial 2	Gallus gallus	141-147
8100229-2	1993	This ligand has been named GlyCAM 1 (Gly-cosylation-dependent Cell Adhesion Molecule 1) because its adhesive interactions with the L selectin lectin domain require that the GlyCAM 1 polypeptide chain be appropriately modified with carbohydrates.	Glycine	27-30	selectin, lymphocyte	Mus musculus	131-141
8321209-4	1993	We isolated a cDNA encoding SRp75 and found that this protein, like other SR proteins, contains an N-terminal RNA recognition motif (RRM), a glycine-rich region, an internal region homologous to the RRM, and a long (315-amino-acid) C-terminal domain composed predominantly of alternating serine and arginine residues.	Glycine	141-148	serine and arginine rich splicing factor 4	Homo sapiens	28-33
8317498-0	1993	Mutation in type II procollagen (COL2A1) that substitutes aspartate for glycine alpha 1-67 and that causes cataracts and retinal detachment: evidence for molecular heterogeneity in the Wagner syndrome and the Stickler syndrome (arthro-ophthalmopathy) A search for mutations in the gene for type II procollagen (COL2A1) was carried out in affected members of a family with early-onset cataracts, lattice degeneration of the retina, and retinal detachment.	Glycine	72-79	collagen type II alpha 1 chain	Homo sapiens	33-39
8317498-6	1993	Comparison with previously reported mutations suggested that mutations introducing premature termination codons in the COL2A1 gene are a frequent cause of the Stickler syndrome, but mutations in the COL2A1 gene that replace glycine codons with codons for bulkier amino acid can produce a broad spectrum of disorders that range from lethal chondrodysplasias to a syndrome involving only ocular tissues, similar to the syndrome in the family originally described by Wagner in 1938.	Glycine	224-231	collagen type II alpha 1 chain	Homo sapiens	199-205
8217523-4	1993	PHM catalyzes the rate limiting step in the formation of alpha-amidated NPY from its glycine extended precursor, a posttranslational modification essential for biologic activity.	Glycine	85-92	neuropeptide Y	Rattus norvegicus	72-75
8325932-4	1993	Analysis of coding sequences of the androgen receptor gene revealed a single nucleotide substitution in exon E, resulting in an amino acid change from glycine (GGG) to valine (GTG) at amino acid 743 within the steroid binding domain of AR.	Glycine	151-158	androgen receptor	Homo sapiens	36-53
8325932-4	1993	Analysis of coding sequences of the androgen receptor gene revealed a single nucleotide substitution in exon E, resulting in an amino acid change from glycine (GGG) to valine (GTG) at amino acid 743 within the steroid binding domain of AR.	Glycine	151-158	androgen receptor	Homo sapiens	236-238
7686366-6	1993	Occupancy of glycoprotein IIb-IIIa in the membranes with RGD (Arg-Gly-Asp)-containing peptides reversibly exposed neoantigenic epitopes and fibrinogen-binding sites in the receptor.	Glycine	66-69	fibrinogen beta chain	Homo sapiens	140-150
8510918-8	1993	Site-directed mutagenesis of the WT1 repression domain revealed that deletion of homopolymeric proline and glycine regions, as well as single amino acid changes, partially inactivated the repression function.	Glycine	107-114	WT1 transcription factor	Homo sapiens	33-36
8415574-1	1993	Thrombin displays remarkable specificity, effecting the removal of fibrinopeptides A and B of fibrinogen through the selective cleavage of two Arg-Gly bonds between the 181 Arg/Lys-Xaa bonds in fibrinogen.	Glycine	147-150	coagulation factor II, thrombin	Homo sapiens	0-8
8318316-5	1993	The phospho-peptide inhibited binding of R1 cells to BSP-coated surfaces 10 times less efficiently compared with the non-phosphorylated peptide, as did, surprisingly, also the fibronectin-derived peptide Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	204-207	integrin binding sialoprotein	Homo sapiens	53-56
8318316-5	1993	The phospho-peptide inhibited binding of R1 cells to BSP-coated surfaces 10 times less efficiently compared with the non-phosphorylated peptide, as did, surprisingly, also the fibronectin-derived peptide Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	204-207	fibronectin 1	Homo sapiens	176-187
8503872-4	1993	gamma E-C(Hx)-phi G (glutathione with a hexyl moiety bound to cysteine and phenylglycine substituted for glycine) specifically bound rat GST 7-7, the Pi-class isoenzyme, from liver, kidney and small intestine.	Glycine	81-88	glutathione S-transferase pi 1	Rattus norvegicus	137-144
8500529-3	1993	Here we show that for the human HLA-DRB1 and HLA-DRB3 gene products this ratio is controlled by the valine/glycine dimorphism at position 86.	Glycine	107-114	major histocompatibility complex, class II, DR beta 1	Homo sapiens	32-40
8390283-8	1993	The 12th mutation GTG--&gt;GGG (valine--&gt;glycine) at codon 216 was expressed in line SCC-12 clone B along with an apparently normal p53 allele and is to our knowledge a novel mutation.	Glycine	44-51	tumor protein p53	Homo sapiens	135-138
7685113-4	1993	Oocytes injected with cRNA synthesized from the hNR1 cDNA express glutamate and NMDA-activated currents in the presence of glycine.	Glycine	123-130	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	48-52
8500529-6	1993	The valine/glycine dimorphism is highly conserved, present in most HLA-DR alleles and influences peptide-binding.	Glycine	11-18	major histocompatibility complex, class II, DR beta 1	Homo sapiens	67-70
8257936-0	1993	Recovery of fibrinogen in cryoprecipitate pasteurized in the presence of sucrose and glycine.	Glycine	85-92	fibrinogen beta chain	Homo sapiens	12-22
8257936-1	1993	The effect of sucrose (60% w/w) and 1 M glycine as thermal stabilizers for fibrinogen in cryoprecipitate was studied.	Glycine	40-47	fibrinogen beta chain	Homo sapiens	75-85
8486712-1	1993	To determine the functional conformation of the Arg-Gly-Asp (RGD) sequence, we have constructed mutant proteins by inserting 4-12 amino acid residues from the RGD region of human fibronectin between Val74 and Asn75 of human lysozyme.	Glycine	52-55	fibronectin 1	Homo sapiens	179-190
8486723-1	1993	Human myristoyl-CoA:protein N-myristoyltransferase (hNmt) catalyzes the transfer of myristate from CoA to the amino-terminal Gly residue of a number of cellular proteins involved in signal transduction pathways, to structural and nonstructural proteins encoded by retroviruses, hepadnaviruses, picornaviruses, and reoviruses, as well as to several transforming tyrosine kinases.	Glycine	125-128	N-myristoyltransferase 1	Homo sapiens	52-56
8488843-6	1993	Family studies failed to demonstrate cosegregation between the new mutations and severe hyperlipoproteinemia, although a number of carriers for the APOE*3(Cys112--&gt;Arg; Arg251--&gt;Gly) allele and the APOE*1(Arg158--&gt;Cys; Leu252--&gt;Glu) allele expressed hypertriglyceridemia and/or hypercholesterolemia.	Glycine	184-187	apolipoprotein E	Homo sapiens	148-154
8488843-6	1993	Family studies failed to demonstrate cosegregation between the new mutations and severe hyperlipoproteinemia, although a number of carriers for the APOE*3(Cys112--&gt;Arg; Arg251--&gt;Gly) allele and the APOE*1(Arg158--&gt;Cys; Leu252--&gt;Glu) allele expressed hypertriglyceridemia and/or hypercholesterolemia.	Glycine	184-187	apolipoprotein E	Homo sapiens	148-152
8358331-1	1993	The synthetic C-terminal peptide fragment of human growth hormone, Leu-Arg-Ile-Val Gln-Cys-Arg-Val-Ser-Glu-Gly-Ser-Cys-Gly-Phe (hGH 177-191), was shown to have antilipogenic activity identical with that of the intact molecule of human growth hormone (hGH).	Glycine	107-110	growth hormone 1	Homo sapiens	51-65
8358331-1	1993	The synthetic C-terminal peptide fragment of human growth hormone, Leu-Arg-Ile-Val Gln-Cys-Arg-Val-Ser-Glu-Gly-Ser-Cys-Gly-Phe (hGH 177-191), was shown to have antilipogenic activity identical with that of the intact molecule of human growth hormone (hGH).	Glycine	107-110	growth hormone 1	Homo sapiens	235-249
8358331-1	1993	The synthetic C-terminal peptide fragment of human growth hormone, Leu-Arg-Ile-Val Gln-Cys-Arg-Val-Ser-Glu-Gly-Ser-Cys-Gly-Phe (hGH 177-191), was shown to have antilipogenic activity identical with that of the intact molecule of human growth hormone (hGH).	Glycine	119-122	growth hormone 1	Homo sapiens	51-65
8358331-1	1993	The synthetic C-terminal peptide fragment of human growth hormone, Leu-Arg-Ile-Val Gln-Cys-Arg-Val-Ser-Glu-Gly-Ser-Cys-Gly-Phe (hGH 177-191), was shown to have antilipogenic activity identical with that of the intact molecule of human growth hormone (hGH).	Glycine	119-122	growth hormone 1	Homo sapiens	235-249
8463322-0	1993	Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin.	Glycine	47-50	actinin alpha 1	Homo sapiens	154-167
8389256-6	1993	The p53 point mutations in the three HCC cell lines from Japan resulted in the amino acid changes of cysteine for tyrosine in cell line HuH 7 at codon 220 (A:T--&gt;G:C), alanine for glycine in cell line HLF at codon 244 (G:C--&gt;C:G), and serine for arginine in cell line HLE at codon 249 (G:C--&gt;C:G).	Glycine	183-190	tumor protein p53	Homo sapiens	4-7
8100572-3	1993	In this study, we report a simple procedure utilizing treatment of serum samples with glycine buffer (pH 1.85) to dissociate antigen-antibody complexes prior to assaying for p24 antigen.	Glycine	86-93	transmembrane p24 trafficking protein 2	Homo sapiens	174-177
8100572-4	1993	A 300% increase in the number of p24-reactive samples and a 3- to 12-fold increase in the quantity of antigen detected were observed when samples were pretreated with 1.5 M glycine buffer (pH 1.85) for 1 hr.	Glycine	173-180	transmembrane p24 trafficking protein 2	Homo sapiens	33-36
8474167-10	1993	(iv) The packaging property of delta Ag-L required a C-terminal Pro/Gly-rich region which is hypothesized to interact with the hepatitis B virus envelope proteins during the assembly process.	Glycine	68-71	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	37-41
8100542-3	1993	Highest concentrations of gastrin (both amidated and the glycine-extended precursor) were observed in the lamb pancreas with gastrin mRNA levels highest at 140 days gestation.	Glycine	57-64	gastrin	Ovis aries	26-33
8100542-5	1993	Only glycine-extended gastrin was detected in the adult pancreas, indicating attenuated processing in mature adult pancreas.	Glycine	5-12	gastrin	Ovis aries	22-29
8332551-5	1993	In addition, the gamma-MSH sequence, contrary to salmon POMC, is present and contains three substitutions, namely a Ser, an Asn, and a Lys residue substituting the normally occurring mammalian Gly, Asp, and Arg residue, respectively.	Glycine	193-196	proopiomelanocortin	Homo sapiens	17-26
8498155-7	1993	The results demonstrate that the substitution of nucleotide (guanine--&gt;cytosine) in exon G of the androgen receptor causes the replacement of an amino acid in position 820 (glycine--&gt;alanine) which occurs in the hormone-binding domain of the androgen receptor.	Glycine	176-183	androgen receptor	Homo sapiens	101-118
8493987-0	1993	Unstable alpha-chain hemoglobin variants with factitious beta-thalassemia biosynthetic ratio: Hb Questembert (alpha 131[H14]Ser-->Pro) and Hb Caen (alpha 132[H15]Val-->Gly).	Glycine	168-171	Fc gamma receptor and transporter	Homo sapiens	9-20
8461968-2	1993	Ten affected individuals are described from a kindred with autosomal dominant familial Alzheimer"s disease in which a mutation in the amyloid precursor protein gene results in a valine to glycine substitution at amyloid precursor protein 717 which co-segregates with the disease.	Glycine	188-195	amyloid beta precursor protein	Homo sapiens	134-159
7683269-6	1993	Inhibition of spreading of Ad2-infected KB cells on FN by the peptide Gly-Arg-Gly-Asp-Ser-Pro is partial, although it is complete in uninfected KB cells.	Glycine	70-73	fibronectin 1	Homo sapiens	52-54
7683269-6	1993	Inhibition of spreading of Ad2-infected KB cells on FN by the peptide Gly-Arg-Gly-Asp-Ser-Pro is partial, although it is complete in uninfected KB cells.	Glycine	78-81	fibronectin 1	Homo sapiens	52-54
8458438-4	1993	The main differences in the spectra of the uniformly 15N-labeled scFv and Fv fragments are due to signals of Gly and Ser from the linker peptide of the scFv fragment.	Glycine	109-112	immunglobulin heavy chain variable region	Homo sapiens	65-69
8458438-4	1993	The main differences in the spectra of the uniformly 15N-labeled scFv and Fv fragments are due to signals of Gly and Ser from the linker peptide of the scFv fragment.	Glycine	109-112	immunglobulin heavy chain variable region	Homo sapiens	152-156
8461464-1	1993	Divalent cation-dependent platelet adhesion to fibronectin (FN) is mediated by the integrin receptors alpha 5 beta 1 (GP Ic-IIa) and alpha IIb beta 3 (GP IIb-IIIa), which recognize the RGD (Arg-Gly-Asp) sequence in the cell-binding domain.	Glycine	194-197	fibronectin 1	Homo sapiens	47-58
8461464-1	1993	Divalent cation-dependent platelet adhesion to fibronectin (FN) is mediated by the integrin receptors alpha 5 beta 1 (GP Ic-IIa) and alpha IIb beta 3 (GP IIb-IIIa), which recognize the RGD (Arg-Gly-Asp) sequence in the cell-binding domain.	Glycine	194-197	fibronectin 1	Homo sapiens	60-62
8096183-2	1993	We have recently reported that streptavidin contains an Arg-Tyr-Asp-Ser (RYDS) sequence which exhibits structural homology to the Arg-Gly-Asp-Ser (RGDS) cell adhesion domain of fibronectin and other matrix-associated glycoproteins.	Glycine	134-137	fibronectin 1	Homo sapiens	177-188
8498155-7	1993	The results demonstrate that the substitution of nucleotide (guanine--&gt;cytosine) in exon G of the androgen receptor causes the replacement of an amino acid in position 820 (glycine--&gt;alanine) which occurs in the hormone-binding domain of the androgen receptor.	Glycine	176-183	androgen receptor	Homo sapiens	248-265
8384554-3	1993	The glycine-rich phosphate anchor of the nucleotide binding fold motif of the protein kinase is a beta ribbon acting as a flap with conformational flexibility over the triphosphate group.	Glycine	4-11	amyloid beta precursor protein	Homo sapiens	96-102
8468356-4	1993	Fibronectin bound specifically to the peptide Gly-Gly-Trp-Ser-His-Trp from the second type I repeat of thrombospondin but not to the corresponding peptides from the first or third repeats or flanking sequences from the second repeat.	Glycine	46-49	fibronectin 1	Homo sapiens	0-11
8468356-4	1993	Fibronectin bound specifically to the peptide Gly-Gly-Trp-Ser-His-Trp from the second type I repeat of thrombospondin but not to the corresponding peptides from the first or third repeats or flanking sequences from the second repeat.	Glycine	50-53	fibronectin 1	Homo sapiens	0-11
8468356-7	1993	The peptide specifically inhibited binding of fibronectin to gelatin or type I collagen and inhibited fibronectin-mediated adhesion of breast carcinoma and melanoma cells to gelatin or type I collagen substrates but not direct adhesion of the cells to fibronectin, which was inhibited by the peptide Gly-Arg-Gly-Asp-Ser.	Glycine	300-303	fibronectin 1	Homo sapiens	46-57
8468356-7	1993	The peptide specifically inhibited binding of fibronectin to gelatin or type I collagen and inhibited fibronectin-mediated adhesion of breast carcinoma and melanoma cells to gelatin or type I collagen substrates but not direct adhesion of the cells to fibronectin, which was inhibited by the peptide Gly-Arg-Gly-Asp-Ser.	Glycine	300-303	fibronectin 1	Homo sapiens	102-113
8468356-7	1993	The peptide specifically inhibited binding of fibronectin to gelatin or type I collagen and inhibited fibronectin-mediated adhesion of breast carcinoma and melanoma cells to gelatin or type I collagen substrates but not direct adhesion of the cells to fibronectin, which was inhibited by the peptide Gly-Arg-Gly-Asp-Ser.	Glycine	300-303	fibronectin 1	Homo sapiens	102-113
8468356-7	1993	The peptide specifically inhibited binding of fibronectin to gelatin or type I collagen and inhibited fibronectin-mediated adhesion of breast carcinoma and melanoma cells to gelatin or type I collagen substrates but not direct adhesion of the cells to fibronectin, which was inhibited by the peptide Gly-Arg-Gly-Asp-Ser.	Glycine	308-311	fibronectin 1	Homo sapiens	46-57
8468356-7	1993	The peptide specifically inhibited binding of fibronectin to gelatin or type I collagen and inhibited fibronectin-mediated adhesion of breast carcinoma and melanoma cells to gelatin or type I collagen substrates but not direct adhesion of the cells to fibronectin, which was inhibited by the peptide Gly-Arg-Gly-Asp-Ser.	Glycine	308-311	fibronectin 1	Homo sapiens	102-113
8468356-7	1993	The peptide specifically inhibited binding of fibronectin to gelatin or type I collagen and inhibited fibronectin-mediated adhesion of breast carcinoma and melanoma cells to gelatin or type I collagen substrates but not direct adhesion of the cells to fibronectin, which was inhibited by the peptide Gly-Arg-Gly-Asp-Ser.	Glycine	308-311	fibronectin 1	Homo sapiens	102-113
8384827-0	1993	Importance of the Arg-Gly-Asp triplet in human thrombin for maintenance of structure and function.	Glycine	22-25	coagulation factor II, thrombin	Homo sapiens	47-55
8384827-1	1993	Site-directed mutagenesis was employed to assess the importance of the Arg-Gly-Asp triplet that comprises residues 197 to 199 in the B-chain of thrombin.	Glycine	75-78	coagulation factor II, thrombin	Homo sapiens	144-152
8383624-6	1993	This ability depends on two glycine residues that decrease the stability of the JunB leucine zipper, resulting in decreased homodimerization and increased heterodimerization.	Glycine	28-35	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	80-84
8432860-7	1993	Net negative balances of alanine, methionine, glycine, threonine and asparagine (typical substrates for system A amino acid transport) also were decreased by insulin, whereas serine (another substrate for system A transport) shifted from a zero balance to net uptake.	Glycine	46-53	insulin	Homo sapiens	158-165
8440915-7	1993	The region of fibronectin recognized by alpha 5 beta 1 contains the amino acid sequence arg-gly-asp (RGD).	Glycine	92-95	fibronectin 1	Homo sapiens	14-25
8320136-2	1993	This allele has an exon-2 nucleotide sequence identical to that of the HLA-DRB1*0801 allele, except for a GGT to GTG change in codon 86, yielding an amino acid substitution (glycine to valine).	Glycine	174-181	major histocompatibility complex, class II, DR beta 1	Homo sapiens	71-79
7679724-2	1993	In the present study, a peptide fragment of beta A4 (beta A4 25-35; Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-NH2), which contains the conserved C-terminal sequence of substance P (X-Gly-Leu-Met-NH2), and the neuropeptide substance P (SP) were examined for their ability to modulate nicotine-evoked secretion from cultured bovine adrenal chromaffin cells.	Glycine	68-71	tachykinin precursor 1	Bos taurus	170-181
7679724-2	1993	In the present study, a peptide fragment of beta A4 (beta A4 25-35; Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-NH2), which contains the conserved C-terminal sequence of substance P (X-Gly-Leu-Met-NH2), and the neuropeptide substance P (SP) were examined for their ability to modulate nicotine-evoked secretion from cultured bovine adrenal chromaffin cells.	Glycine	68-71	tachykinin precursor 1	Bos taurus	224-235
7679724-2	1993	In the present study, a peptide fragment of beta A4 (beta A4 25-35; Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-NH2), which contains the conserved C-terminal sequence of substance P (X-Gly-Leu-Met-NH2), and the neuropeptide substance P (SP) were examined for their ability to modulate nicotine-evoked secretion from cultured bovine adrenal chromaffin cells.	Glycine	84-87	tachykinin precursor 1	Bos taurus	170-181
7679724-2	1993	In the present study, a peptide fragment of beta A4 (beta A4 25-35; Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-NH2), which contains the conserved C-terminal sequence of substance P (X-Gly-Leu-Met-NH2), and the neuropeptide substance P (SP) were examined for their ability to modulate nicotine-evoked secretion from cultured bovine adrenal chromaffin cells.	Glycine	84-87	tachykinin precursor 1	Bos taurus	224-235
8492914-2	1993	All of the neuropeptide Y-immuno-reactive neurons were also GABA-immunoreactive, but they were either non-immunoreactive or weakly immunoreactive with the glycine antiserum.	Glycine	155-162	neuropeptide Y	Rattus norvegicus	11-25
8483792-3	1993	Peptides to which the sequence of Arg-Gly-Asp-Val (RGDV) had been added at the carboxy-terminus of (Lys-Arg)n, Lysn, or Argn also inhibited vWF binding.	Glycine	38-41	von Willebrand factor	Homo sapiens	140-143
8451200-8	1993	Two genes encode hnRNP A/B proteins with two RRMs and a glycine-rich domain.	Glycine	56-63	heterogeneous nuclear ribonucleoprotein A/B L homeolog	Xenopus laevis	17-26
8094956-3	1993	We have undertaken a detailed NMR conformational study in a DMSOd6/H2O cryomixture at 278 K of the CCK analog H-Arg-Asp-Tyr(SO3H)-Thr-Gly-Trp-Nle-Asp-PheNH2 (CCK9) which retains all the bioactivities of CCK8, but was found to be remarkably more stable in acidic media and unaffected by air oxidation due to Met replacements.	Glycine	134-137	cholecystokinin	Homo sapiens	99-102
8514235-4	1993	Comparison of amino acid sequences of DRB1*0405 with other DRB1 alleles suggested that the risk for RA was closely associated with particular amino acid residues of DR beta chain, i. e. glycine residue at the 86th position in addition to the residues between 70th and 74th position.	Glycine	186-193	major histocompatibility complex, class II, DR beta 1	Homo sapiens	38-42
8514235-4	1993	Comparison of amino acid sequences of DRB1*0405 with other DRB1 alleles suggested that the risk for RA was closely associated with particular amino acid residues of DR beta chain, i. e. glycine residue at the 86th position in addition to the residues between 70th and 74th position.	Glycine	186-193	major histocompatibility complex, class II, DR beta 1	Homo sapiens	59-63
7680185-0	1993	Modulation of vitronectin receptor-mediated osteoclast adhesion by Arg-Gly-Asp peptide analogs: a structure-function analysis.	Glycine	71-74	vitronectin	Rattus norvegicus	14-25
8474556-9	1993	The endogenous amino acids, glycine, taurine and N-acetylaspartic acid, also significantly inhibited PAG activity in the 5-10 mM range.	Glycine	28-35	glutaminase 2	Homo sapiens	101-104
8380163-0	1993	Mutagenesis of the amino-terminal glycine to alanine in Gs alpha subunit alters beta gamma-dependent properties and decreases adenylylcyclase activation.	Glycine	34-41	GNAS complex locus	Homo sapiens	56-64
8093615-2	1993	At variance with platelet alpha IIb beta 3 or endothelial cell alpha v beta 3 integrins, CD11b/CD18 interacts with a approximately 30-kDa plasmic fragment D (D30) of fibrinogen that lacks the Arg-Gly-Asp sequences in the A alpha chain and the carboxyl terminus of the gamma chain.	Glycine	196-199	integrin subunit beta 2	Homo sapiens	95-99
8093355-7	1993	This sequence is Gly-Xa-Xa-Xa-Gly, represented by Gly505-Ser-Asn-Tyr-Gly509 in the case of ANF-RGC ARM and by Gly499-Ser-Ser-Tyr-Gly503 in the CNP receptor guanylate cyclase ARM.	Glycine	17-20	natriuretic peptide A	Homo sapiens	91-94
8093355-7	1993	This sequence is Gly-Xa-Xa-Xa-Gly, represented by Gly505-Ser-Asn-Tyr-Gly509 in the case of ANF-RGC ARM and by Gly499-Ser-Ser-Tyr-Gly503 in the CNP receptor guanylate cyclase ARM.	Glycine	30-33	natriuretic peptide A	Homo sapiens	91-94
8380163-11	1993	Although not essential for association with beta gamma subunits, the amino-terminal glycine of nonmyristoylated Gs alpha might play a modulatory role in this interaction.	Glycine	84-91	GNAS complex locus	Homo sapiens	112-120
8456092-5	1993	In other mammalian cells glycine is a substrate for the A, ASC and Gly amino acid transport systems.	Glycine	25-32	PYD and CARD domain containing	Homo sapiens	59-62
8364096-2	1993	The fibronectin cell binding domain -Arg-Gly-Asp-Ser- (-RGDS-) localizes at the junction of hydrophobicity and hydrophilicity.	Glycine	41-44	fibronectin 1	Homo sapiens	4-15
8094879-0	1993	The strongly conserved carboxyl-terminus glycine-methionine motif of the Escherichia coli GroEL chaperonin is dispensable.	Glycine	41-48	GroEL	Escherichia coli	90-95
8094879-4	1993	We have altered the groEL gene (encoding the essential Escherichia coli HSP60 chaperonin) so that the protein produced lacks its 16 final (including nine gly, and five met) residues.	Glycine	154-157	GroEL	Escherichia coli	20-25
8380125-6	1993	Treatment of ECM with glycine (pH 2.7), which removes plasminogen activator inhibitor from the matrix, results in an increase in the rate of ACCS ECM degradation by uPA.	Glycine	22-29	plasminogen activator, urokinase	Homo sapiens	165-168
7680587-7	1993	Motions with high amplitudes have been localized in the Gly-Pro-Gly sequence which forms a beta-turn in both structures.	Glycine	56-59	amyloid beta precursor protein	Homo sapiens	89-95
7680587-7	1993	Motions with high amplitudes have been localized in the Gly-Pro-Gly sequence which forms a beta-turn in both structures.	Glycine	64-67	amyloid beta precursor protein	Homo sapiens	89-95
1451011-5	1992	These acidic proteins can affect the surface properties of collagen fibril, and BSP, having the cell-attachment sequence Arg-Gly-Asp, possibly mediates interaction between collagen fibril and cells.	Glycine	125-128	integrin binding sialoprotein	Homo sapiens	80-83
1479591-0	1992	Potent inhibitors of platelet aggregation based upon the Arg-Gly-Asp-Phe sequence of fibrinogen.	Glycine	61-64	fibrinogen beta chain	Homo sapiens	85-95
1445924-0	1992	Nonlocal structural perturbations in a mutant human insulin: sequential resonance assignment and 13C-isotope-aided 2D-NMR studies of [PheB24--&gt;Gly]insulin with implications for receptor recognition.	Glycine	146-149	insulin	Homo sapiens	52-59
1445924-0	1992	Nonlocal structural perturbations in a mutant human insulin: sequential resonance assignment and 13C-isotope-aided 2D-NMR studies of [PheB24--&gt;Gly]insulin with implications for receptor recognition.	Glycine	146-149	insulin	Homo sapiens	150-157
1445924-4	1992	The mutant insulin retains near-native receptor-binding affinity despite a nonconservative substitution (PheB24--&gt;Gly) in the receptor-binding surface.	Glycine	117-120	insulin	Homo sapiens	11-18
1385407-9	1992	Replacement of 1 of these residues, a cysteine, with the consensus glycine, conferred SH2-C binding activity toward tyrosine-phosphorylated p62 and epidermal growth factor receptor.	Glycine	67-74	epidermal growth factor receptor	Homo sapiens	148-180
1493949-3	1992	This was based on the recent finding that the sequence of the binding domain of the platelet membrane receptor to fibrinogen was identified as TDVNGDGRHDL (one-letter amino acid code; Thr-Asp-Val-Asn-Gly-Asp-Gly-Arg-His-Asp-Leu), entitled B12.	Glycine	200-203	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	239-242
1493949-3	1992	This was based on the recent finding that the sequence of the binding domain of the platelet membrane receptor to fibrinogen was identified as TDVNGDGRHDL (one-letter amino acid code; Thr-Asp-Val-Asn-Gly-Asp-Gly-Arg-His-Asp-Leu), entitled B12.	Glycine	208-211	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	239-242
1469085-6	1992	A synthetic peptide of the Arg-Gly-Asp (RGD) domain in entactin, SIGFRGDGQTC (S-RGD), mediated PMN adhesion and chemotaxis, and preexposure of PMN to S-RGD blocked PMN adhesion and chemotaxis induced by entactin without diminishing the adhesive and chemotactic activities of fMLP.	Glycine	31-34	formyl peptide receptor 1	Homo sapiens	275-279
1445269-1	1992	By site-directed mutagenesis of a human complement factor C5a cDNA clone, we have designed a hybrid anaphylatoxin in which three amino acid residues in the C-terminal sequence of human C5a were exchanged to create the native C-terminal human C3a (hC3a) sequence Leu-Gly-Leu-Ala-Arg.	Glycine	266-269	complement C5a receptor 1	Homo sapiens	58-61
1445269-1	1992	By site-directed mutagenesis of a human complement factor C5a cDNA clone, we have designed a hybrid anaphylatoxin in which three amino acid residues in the C-terminal sequence of human C5a were exchanged to create the native C-terminal human C3a (hC3a) sequence Leu-Gly-Leu-Ala-Arg.	Glycine	266-269	complement C5a receptor 1	Homo sapiens	185-188
1426258-3	1992	Peptides Ala-783-Lys-799 and Ala-783-Arg-798 inhibited calmodulin independent MLCK at the same potency as the peptide Ala-783-Gly-804.	Glycine	126-129	calmodulin 1	Homo sapiens	55-65
1416988-8	1992	Comparison of different synthetic peptide substrates showed Pim-1 to have a strong substrate preference for the peptide Lys-Arg-Arg-Ala-Ser*-Gly-Pro with an almost sixfold higher specificity constant kcat/Km over that of the substrate Kemptide (Leu-Arg-Arg-Ala-Ser*-Leu-Gly).	Glycine	141-144	Pim-1 proto-oncogene, serine/threonine kinase	Bos taurus	60-65
1359796-1	1992	Glycine (Gly)-extended gastrin has been described as the inactive precursor form of the biologically active amidated gastrin.	Glycine	0-7	gastrin	Ovis aries	23-30
1359796-1	1992	Glycine (Gly)-extended gastrin has been described as the inactive precursor form of the biologically active amidated gastrin.	Glycine	0-7	gastrin	Ovis aries	117-124
1359796-1	1992	Glycine (Gly)-extended gastrin has been described as the inactive precursor form of the biologically active amidated gastrin.	Glycine	0-3	gastrin	Ovis aries	23-30
1359796-1	1992	Glycine (Gly)-extended gastrin has been described as the inactive precursor form of the biologically active amidated gastrin.	Glycine	0-3	gastrin	Ovis aries	117-124
1420332-0	1992	Interaction of troponin I and troponin C: use of the two-dimensional transferred nuclear Overhauser effect to determine the structure of a Gly-110 inhibitory troponin I peptide analog when bound to cardiac troponin C. The structure of a peptide analog of the inhibitory region of cardiac troponin-I (N-acetyl-G110-TnI(104-115) amide) when bound to cardiac troponin-C has been determined by 2-dimensional 1H-NMR techniques.	Glycine	139-142	troponin C1, slow skeletal and cardiac type	Homo sapiens	348-366
1363428-6	1992	Human loricrin in 26 kDa and consists of three long glycine-serine-cysteine rich sequence domains that contain quasi-repeating peptides and which form the novel glycine loop motif.	Glycine	52-59	loricrin cornified envelope precursor protein	Homo sapiens	6-14
1282482-5	1992	Neuropeptide gamma was the most abundant peptide and its primary structure was established as Asp-Ala-Gly-Tyr-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser- Phe-Val-Gly-Leu-Met-NH2.	Glycine	102-105	tachykinin precursor 1	Homo sapiens	0-18
1429834-1	1992	The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in glycine and arginine (GAR domain).	Glycine	142-149	rRNA methyltransferase NOP1	Saccharomyces cerevisiae S288C	28-32
1363428-6	1992	Human loricrin in 26 kDa and consists of three long glycine-serine-cysteine rich sequence domains that contain quasi-repeating peptides and which form the novel glycine loop motif.	Glycine	161-168	loricrin cornified envelope precursor protein	Homo sapiens	6-14
1429834-1	1992	The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in glycine and arginine (GAR domain).	Glycine	142-149	H/ACA snoRNP pseudouridylase subunit GAR1	Saccharomyces cerevisiae S288C	40-44
1363428-9	1992	By use of PCR analyses, we have found that human loricrin consists of two allelic size variants, due to sequence variations in the second glycine loop domain only, and these variants segregate in the human population by normal Mendelian mechanisms.	Glycine	138-145	loricrin cornified envelope precursor protein	Homo sapiens	49-57
1397309-2	1992	In the NMDAR1 subunit, the signal of agonist binding may be carried from Y456 to W590 through an electron transport chain, including W480 which could be the glycine modulatory site.	Glycine	157-164	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	7-13
1481205-2	1992	DRB1*0413 is a DRB1*0401-variant differing from DRB1*0401 only at codon 86 where valine is present instead of glycine.	Glycine	110-117	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-4
1481205-2	1992	DRB1*0413 is a DRB1*0401-variant differing from DRB1*0401 only at codon 86 where valine is present instead of glycine.	Glycine	110-117	major histocompatibility complex, class II, DR beta 1	Homo sapiens	15-19
1481205-2	1992	DRB1*0413 is a DRB1*0401-variant differing from DRB1*0401 only at codon 86 where valine is present instead of glycine.	Glycine	110-117	major histocompatibility complex, class II, DR beta 1	Homo sapiens	15-19
1279141-0	1992	Cysteine and glycine supplementation modulate the metabolic response to tumor necrosis factor alpha in rats fed a low protein diet.	Glycine	13-20	tumor necrosis factor	Rattus norvegicus	72-99
1279141-4	1992	Glycine and cysteine supplementation resulted in greater liver weight after TNF treatment than did alanine supplementation.	Glycine	0-7	tumor necrosis factor	Rattus norvegicus	76-79
1328674-5	1992	Sites of protease cleavage were identified in the deduced amino acid sequence of mu 1 by determining the amino-terminal sequences of phi proteins: trypsin cleaves between arginine 584 and isoleucine 585, and chymotrypsin cleaves between tyrosine 581 and glycine 582.	Glycine	254-261	glutathione S-transferase mu 1	Homo sapiens	81-85
16653139-1	1992	The effects of glycine, alanine, serine, and various phosphorylated metabolites on the activity of phosphoenolpyruvate (PEP) carboxylase from Zea mays and Crassula argentea were studied.	Glycine	15-22	phosphoenolpyruvate carboxylase 2	Zea mays	120-123
16653139-3	1992	The combination of glycine and glucose 6-phosphate synergistically reduced the apparent K(m) of the enzyme for PEP and increased the apparent V(max).	Glycine	19-26	phosphoenolpyruvate carboxylase 2	Zea mays	111-114
1449603-3	1992	Furthermore, the short-range compact regions correspond well to the biologically active areas of atriopeptin (103-125)-amide (which is homologous peptide to alpha-hANP), detected by the glycine substitution technique (Konishi et al., 1987).	Glycine	186-193	natriuretic peptide A	Homo sapiens	97-108
1465214-1	1992	The brain tissue from a case of familial Alzheimer"s disease (FAD) caused by a missense (valine to glycine) mutation at codon 717 of the amyloid precursor protein (APP) gene has been examined for the presence of abnormally phosphorylated paired helical filament tau (PHF-tau).	Glycine	99-106	amyloid beta precursor protein	Homo sapiens	137-162
1397082-4	1992	Attachment was inhibited by exposure of the fibronectin-coated surfaces to antibodies against the cell binding domain of fibronectin or by incubating the cells with peptides containing the recognition sequence Arg-Gly-Asp (RGD) known from vertebrate cells.	Glycine	214-217	fibronectin 1	Homo sapiens	44-55
1383494-5	1992	aFGF, basic fibroblast growth factor and several glycine-substituted point mutations of aFGF potently inhibited 0.1 nM [125I]aFGF binding.	Glycine	49-56	fibroblast growth factor 1	Homo sapiens	88-92
1383494-5	1992	aFGF, basic fibroblast growth factor and several glycine-substituted point mutations of aFGF potently inhibited 0.1 nM [125I]aFGF binding.	Glycine	49-56	fibroblast growth factor 1	Homo sapiens	88-92
1328207-1	1992	A methionine aminopeptidase that specifically removes methionine residues from peptides with amino-terminal sequences of Met-Ala-, Met-Val-, Met-Ser-, Met-Gly-, and Met-Pro- but not Met-Leu- or Met-Lys- has been isolated to homogeneity from porcine liver by a procedure involving five chromatographic steps.	Glycine	155-158	aminopeptidase	Saccharomyces cerevisiae S288C	13-27
1409710-3	1992	A missense mutation, Gly-561--&gt;Ser, was identified within the proposed glycoprotein Ib binding domain of vWF in the proband with von Willebrand disease type B, a unique variant characterized by no ristocetin-induced, but normal botrocetin-induced, binding to glycoprotein Ib.	Glycine	21-24	von Willebrand factor	Homo sapiens	108-111
1386557-6	1992	The proliferation of melanoma cells to FN and to FN fragments was also significantly inhibited by peptides containing the Arg-Gly-Asp sequence.	Glycine	126-129	fibronectin 1	Homo sapiens	39-41
1355480-5	1992	Polymerase chain reaction analyses of genomic DNAs from different individuals show that human loricrin consists of two allelic size variants, due to sequence variations in its second glycine loop domain, and these variants segregate in the human population by normal Mendelian mechanisms.	Glycine	183-190	loricrin cornified envelope precursor protein	Homo sapiens	94-102
1331655-4	1992	A second component, which exhibited a shorter retention time, co-eluted with the glycine-extended form of desacetyl alpha-MSH [ACTH(1-14)].	Glycine	81-88	proopiomelanocortin	Homo sapiens	116-125
1387328-4	1992	The deduced amino acid sequence of the pea dehydrin encoded by B12 is 197 amino acids in length, has a high glycine content (25.9%), lacks tryptophan and is highly hydrophilic.	Glycine	108-115	dehydrin	Zea mays	43-51
1386557-5	1992	Mapping of FN regions responsible for the proliferative signal was performed by stimulating melanoma cells with different FN proteolytic fragments and indicated that a significant mitogenic signal was provided by the M(r) 120,000 alpha-chymotrypsin fragment containing the Arg-Gly-Asp sequence.	Glycine	277-280	fibronectin 1	Homo sapiens	11-13
1386557-6	1992	The proliferation of melanoma cells to FN and to FN fragments was also significantly inhibited by peptides containing the Arg-Gly-Asp sequence.	Glycine	126-129	fibronectin 1	Homo sapiens	49-51
1354852-8	1992	The hnRNPs contain the glycine-rich domain in the C-terminal half of the molecule, which also seemed to be in PrPc at the N-terminal half of the molecule.	Glycine	23-30	prion protein	Homo sapiens	110-114
1644811-3	1992	The carboxyl-terminal half of NSR1, consisting of two tandemly repeated putative RNA-binding domains and a glycine/arginine-rich domain, has 37% amino acid sequence identity with the same part of mammalian nucleolin, while no sequence similarities are found between their amino-terminal regions.	Glycine	107-114	scavenger receptor class F member 2	Homo sapiens	30-34
1379413-1	1992	The glycine-to-aspartic acid missense mutation at codon 551 (G551D), which is within the first nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator (CFTR), is the third most common cystic fibrosis (CF) mutation, with a worldwide frequency of 3.1% among CF chromosomes.	Glycine	4-11	CF transmembrane conductance regulator	Homo sapiens	126-177
1379413-1	1992	The glycine-to-aspartic acid missense mutation at codon 551 (G551D), which is within the first nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator (CFTR), is the third most common cystic fibrosis (CF) mutation, with a worldwide frequency of 3.1% among CF chromosomes.	Glycine	4-11	CF transmembrane conductance regulator	Homo sapiens	179-183
1631133-6	1992	The second peptide is identical to a form of GnRH originally isolated from chicken brains (chicken GnRH-II; pGlu-His-Trp-Ser-His-Gly-Trp-Tyr- Pro-Gly-NH2) and is widespread throughout the vertebrates.	Glycine	129-132	mitochondrial ribosomal protein S26	Gallus gallus	99-106
1643115-7	1992	(3) Arg-Gly-Asp-Ser (RGDS) peptide, a synthetic anti-adhesive peptide, inhibited aggregation of thrombin-activated platelets in a dose-dependent manner (100-200 microM).	Glycine	8-11	coagulation factor II, thrombin	Homo sapiens	96-104
1631133-6	1992	The second peptide is identical to a form of GnRH originally isolated from chicken brains (chicken GnRH-II; pGlu-His-Trp-Ser-His-Gly-Trp-Tyr- Pro-Gly-NH2) and is widespread throughout the vertebrates.	Glycine	146-149	mitochondrial ribosomal protein S26	Gallus gallus	99-106
1637301-3	1992	In order to release mature recombinant-derived hIGF-I (rhIGF-I), the fusion protein is treated with hydroxylamine, which cleaves a susceptible Asn-Gly bond that has been engineered into the fusion protein gene.	Glycine	147-150	insulin like growth factor 1	Homo sapiens	47-53
1359610-3	1992	Omeprazole inhibited acid secretion-pH increased from 3.0 to 7.1 at 24 h. Plasma amidated and glycine extended gastrin increased 3-fold while the ratio of amidated to glycine extended gastrins (4:1) remained unchanged.	Glycine	94-101	gastrin	Ovis aries	111-118
1359610-5	1992	Gastrin-17 (amidated and glycine extended) was the predominant form in the circulation and antrum, although there were preferential increases in larger forms following omeprazole treatment.	Glycine	25-32	gastrin	Ovis aries	0-7
1632660-5	1992	The adherence of synovial cells to hyaluronidase treated cartilage slices in vitro was specifically inhibited by the synthetic peptide, Gly-Arg-Gly-Asp-Ser-Pro, which is the adhesive portion of the fibronectin molecule.	Glycine	136-139	fibronectin 1	Homo sapiens	198-209
1632660-5	1992	The adherence of synovial cells to hyaluronidase treated cartilage slices in vitro was specifically inhibited by the synthetic peptide, Gly-Arg-Gly-Asp-Ser-Pro, which is the adhesive portion of the fibronectin molecule.	Glycine	144-147	fibronectin 1	Homo sapiens	198-209
1376965-6	1992	It is interesting that such glycine substitutions inside the COL1A1 or COL1A2 genes have been associated with many cases of osteogenesis imperfecta.	Glycine	28-35	collagen type I alpha 2 chain	Homo sapiens	71-77
1618760-7	1992	In contrast, an unrelated Type B patient of European descent (proband 3) was heteroallelic for two missense mutations, a G to A transition in exon 2 which predicted a glycine to arginine substitution at ASM codon 242 (designated G242R), and an A to G transition in exon 3 which resulted in an asparagine to serine substitution at codon 383 (designated N383S).	Glycine	167-174	sphingomyelin phosphodiesterase 1	Homo sapiens	203-206
1617834-4	1992	In contrast, a mutein of TNF-alpha, designated as F4236, having the cell-adhesive sequence (Tyr-Ile-Gly-Ser-Arg) at the N-terminus of the TNF molecule did not enhance metastasis, but rather exhibited similar antitumor activity to wild-type TNF-alpha in fibrosarcoma-bearing mice.	Glycine	100-103	tumor necrosis factor	Mus musculus	25-34
1617834-4	1992	In contrast, a mutein of TNF-alpha, designated as F4236, having the cell-adhesive sequence (Tyr-Ile-Gly-Ser-Arg) at the N-terminus of the TNF molecule did not enhance metastasis, but rather exhibited similar antitumor activity to wild-type TNF-alpha in fibrosarcoma-bearing mice.	Glycine	100-103	tumor necrosis factor	Mus musculus	25-28
1421807-1	1992	Recombinant alpha-amidating enzyme was used in the semisynthesis (1-5 mg scale) of human growth hormone-releasing factor, GRF(1-44)-NH2, by in vitro enzymatic oxidation of the glycine-extended precursor, GRF(1-44)-Gly-OH, prepared by solid-phase synthesis.	Glycine	176-183	growth hormone releasing hormone	Homo sapiens	89-120
1421807-1	1992	Recombinant alpha-amidating enzyme was used in the semisynthesis (1-5 mg scale) of human growth hormone-releasing factor, GRF(1-44)-NH2, by in vitro enzymatic oxidation of the glycine-extended precursor, GRF(1-44)-Gly-OH, prepared by solid-phase synthesis.	Glycine	214-220	growth hormone releasing hormone	Homo sapiens	89-120
1592482-10	1992	Inhibitory angiotensin II activity is responsible for decreasing proximal reabsorption during glycine; however, factors other than angiotensin II limit the glomerular response to glycine.	Glycine	94-101	angiotensinogen	Rattus norvegicus	11-25
1595707-5	1992	In the model of radiocontrast nephropathy, the percentage of medullary thick ascending limb (mTAL) necrosis at 24 hours increased from 22% +/- 6% to 41% +/- 9% or 55% +/- 7% with glycine infusion of 75 or 135 minutes, respectively (mean +/- SE, P less than 0.05, analysis of variance [ANOVA]).	Glycine	179-186	talipes	Mus musculus	93-97
1595707-10	1992	Both uninephrectomy and glycine infusion were found to contribute to mTAL necrosis.	Glycine	24-31	talipes	Mus musculus	69-73
1581297-1	1992	Fibrinogen Lille, a congenital dysfibrinogenemia, has been reported to arise from a mutation from Asp to Asn at position 7 of the A alpha chain of human fibrinogen, thereby reducing the thrombin-catalyzed rate of hydrolysis of the Arg(16)-Gly(17) peptide bond of this chain.	Glycine	239-242	fibrinogen beta chain	Homo sapiens	0-10
1577789-7	1992	However, the Arg-Gly-Asp-containing synthetic peptide Gly-Arg-Gly-Asp-Ser-Pro significantly inhibited cell attachment to MGP, whereas the control peptide Gly-Arg-Gly-Glu-Ser-Pro had minimal effect.	Glycine	17-20	matrix Gla protein	Bos taurus	121-124
1577789-7	1992	However, the Arg-Gly-Asp-containing synthetic peptide Gly-Arg-Gly-Asp-Ser-Pro significantly inhibited cell attachment to MGP, whereas the control peptide Gly-Arg-Gly-Glu-Ser-Pro had minimal effect.	Glycine	54-57	matrix Gla protein	Bos taurus	121-124
1577789-7	1992	However, the Arg-Gly-Asp-containing synthetic peptide Gly-Arg-Gly-Asp-Ser-Pro significantly inhibited cell attachment to MGP, whereas the control peptide Gly-Arg-Gly-Glu-Ser-Pro had minimal effect.	Glycine	54-57	matrix Gla protein	Bos taurus	121-124
1577789-7	1992	However, the Arg-Gly-Asp-containing synthetic peptide Gly-Arg-Gly-Asp-Ser-Pro significantly inhibited cell attachment to MGP, whereas the control peptide Gly-Arg-Gly-Glu-Ser-Pro had minimal effect.	Glycine	54-57	matrix Gla protein	Bos taurus	121-124
1577789-8	1992	These data indicate that MGP may function in mediating cell attachment to the extracellular matrix via a receptor that requires intact Gla residues and that can be inhibited by Arg-Gly-Asp-containing peptides.	Glycine	181-184	matrix Gla protein	Bos taurus	25-28
1374906-3	1992	Single-strand conformation polymorphism and direct sequencing analysis identified a G----A transition, resulting in a glycine substitution at amino acid 574 of the pro alpha 1(II) collagen triple-helical domain.	Glycine	118-125	collagen type II alpha 1 chain	Homo sapiens	164-188
1581297-1	1992	Fibrinogen Lille, a congenital dysfibrinogenemia, has been reported to arise from a mutation from Asp to Asn at position 7 of the A alpha chain of human fibrinogen, thereby reducing the thrombin-catalyzed rate of hydrolysis of the Arg(16)-Gly(17) peptide bond of this chain.	Glycine	239-242	fibrinogen beta chain	Homo sapiens	34-44
1581297-1	1992	Fibrinogen Lille, a congenital dysfibrinogenemia, has been reported to arise from a mutation from Asp to Asn at position 7 of the A alpha chain of human fibrinogen, thereby reducing the thrombin-catalyzed rate of hydrolysis of the Arg(16)-Gly(17) peptide bond of this chain.	Glycine	239-242	coagulation factor II, thrombin	Homo sapiens	186-194
1581297-2	1992	Synthetic peptides of relevant portions of the wild-type and mutant A alpha chains were prepared, and the thrombin-catalyzed rates of hydrolysis of their Arg(16)-Gly(17) peptide bonds were determined.	Glycine	162-165	coagulation factor II, thrombin	Homo sapiens	106-114
1290488-1	1992	Hirulog-1 [D-Phe-Pro-Arg-Pro-[Gly]4-desulphohirudin-(53-64) (HV1)] was designed to bind by its first four and last 12 residues to the alpha-thrombin catalytic site and anion-binding exosite for fibrin(ogen) recognition respectively, with a [Gly]4 bridge and an Arg-Pro bond at the scissional position.	Glycine	30-33	coagulation factor II, thrombin	Homo sapiens	140-148
1580841-2	1992	Three members of one family and one person from another family were found to have a guanine-to-adenine transition mutation in the first nucleotide of codon 106 in the rhodopsin gene that results in a glycine-to-arginine change.	Glycine	200-207	rhodopsin	Homo sapiens	167-176
1314596-3	1992	Replacement of one of the two conserved Trp residues in the motif to Gly was found to completely abolish the binding of erythropoietin to the receptor and also to lose the ability to transduce the factor-dependent growth signal.	Glycine	69-72	erythropoietin	Homo sapiens	120-134
1507480-3	1992	The first instance demonstrated a G----C transversion at codon 365 from GGA (Gly) to CGA (Arg), which was seen in three individuals of the two families.	Glycine	77-80	chromogranin A	Homo sapiens	85-88
1567424-4	1992	In addition, the Pro-17-Gly peptide competitively inhibited association between hsp70 and p53, an activity which was determined by immunoprecipitation with anti-p53 monoclonal antibody PAb240.	Glycine	24-27	tumor protein p53	Homo sapiens	90-93
1339453-0	1992	Defective folding and stable association with protein disulfide isomerase/prolyl hydroxylase of type I procollagen with a deletion in the pro alpha 2(I) chain that preserves the Gly-X-Y repeat pattern.	Glycine	178-181	collagen type I alpha 2 chain	Homo sapiens	96-114
1560020-4	1992	Excellent electron density could be traced for the decapeptide, beginning with Asp-7f and ending with Arg-16f in the active site of thrombin; the remaining 4 residues, which have been cleaved from the tetradecapeptide at the Arg-16f/Gly-17f bond, are not seen.	Glycine	233-236	coagulation factor II, thrombin	Homo sapiens	132-140
1567424-4	1992	In addition, the Pro-17-Gly peptide competitively inhibited association between hsp70 and p53, an activity which was determined by immunoprecipitation with anti-p53 monoclonal antibody PAb240.	Glycine	24-27	tumor protein p53	Homo sapiens	161-164
1314499-5	1992	Internalization of bound 125I-PYY was suggested by slow and incomplete dissociation in the presence of unlabeled PYY (50% after 2 h) and was examined further by measuring residual binding after washing with acetic acid (pH 2.5), glycine (pH 10.5), or trypsin.	Glycine	229-236	peptide YY	Homo sapiens	30-33
1349567-8	1992	Upon sequencing, this codon contained a novel missense mutation, a C-to-G transversion changing CGA (Arg 1696) to GGA (Gly).	Glycine	119-122	chromogranin A	Homo sapiens	96-99
1352760-3	1992	The size difference observed between the two proteins is due to two point mutations in the coding region of the KAP mRNA, leading to two amino-acid changes one of which resulted in the substitution of a glycine for a glutamic acid.	Glycine	203-210	kidney androgen regulated protein	Mus musculus	112-115
1347009-5	1992	Similar changes occurred with plasma glycine-extended gastrin (gastrin-gly).	Glycine	37-44	gastrin	Ovis aries	54-61
1548743-9	1992	Greater than 98% of the total recovered p17 was myristylated at the N-terminal glycine residue, and the measured molecular weights (as determined by electrospray ionization mass spectrometry) of the most abundant forms were within 3 atomic mass units of the calculated molecular weights (15,266).	Glycine	79-86	family with sequence similarity 72 member B	Homo sapiens	40-43
1547341-0	1992	Antithrombin-III-Stockholm: a codon 392 (Gly----Asp) mutation with normal heparin binding and impaired serine protease reactivity.	Glycine	41-44	coagulation factor II, thrombin	Homo sapiens	103-118
1339347-7	1992	The composite MP5 cDNA was 897 nucleotides long and contained an open reading frame capable of encoding a 260-residue-long salivary PRP precursor (30% Pro, 19% Gln and 18% Gly), containing nine variant repeat units of consensus PGNQQGPPPQGGPQQ(GPP)R(PPQ).	Glycine	172-175	proline-rich protein MP5	Mus musculus	14-17
1556186-6	1992	Pretreatment with an AII receptor antagonist, DuP 753, normalized the response to glycine at both glomerular and tubular levels.	Glycine	82-89	angiotensinogen	Rattus norvegicus	21-24
1547506-5	1992	The C-terminal half of p110, which is linked to the p50 portion via a glycine-rich hinge, could also noncovalently bind to p50.	Glycine	70-77	nuclear factor kappa B subunit 1	Homo sapiens	52-55
1547506-5	1992	The C-terminal half of p110, which is linked to the p50 portion via a glycine-rich hinge, could also noncovalently bind to p50.	Glycine	70-77	nuclear factor kappa B subunit 1	Homo sapiens	123-126
1544488-3	1992	These results indicate that matrix assembly of fibronectin requires both regions and can proceed in the absence of the type III repeats including the one containing the cell adhesive Arg-Gly-Asp sequence.	Glycine	187-190	fibronectin 1	Homo sapiens	47-58
1347009-5	1992	Similar changes occurred with plasma glycine-extended gastrin (gastrin-gly).	Glycine	37-44	gastrin	Ovis aries	63-70
1347009-7	1992	Gastrin mRNA paralleled the changes in antral gastrin-gly.	Glycine	54-57	gastrin	Ovis aries	0-7
1347009-7	1992	Gastrin mRNA paralleled the changes in antral gastrin-gly.	Glycine	54-57	gastrin	Ovis aries	46-53
1737795-0	1992	Selective inactivation of the Arg-Gly-Asp-Ser (RGDS) binding site in von Willebrand factor by site-directed mutagenesis.	Glycine	34-37	von Willebrand factor	Homo sapiens	69-90
1737016-1	1992	Isotope labeling of recombinant normal cardiac troponin C (cTnC3) with 15N-enriched amino acids and multidimensional NMR were used to assign the downfield-shifted amide protons of Gly residues at position 6 in Ca(2+)-binding loops II, III, and IV, as well as tightly hydrogen-bonded amides within the short antiparallel beta-sheets between pairs of Ca(2+)-binding loops.	Glycine	180-183	troponin C1, slow skeletal and cardiac type	Homo sapiens	39-57
1737757-8	1992	Our studies reveal that the individual mutation of several hydrophobic amino acid residues such as Leu813, Ile810, and Trp800 and the glycine residue Gly804 also resulted in a severe decrease in or complete loss of CaM binding and activation of smMLCK.	Glycine	134-141	calmodulin 1	Homo sapiens	215-218
1737795-2	1992	A glycine to alanine substitution yielded RADS-vWF, while an aspartate to glutamate substitution resulted in RGES-vWF.	Glycine	2-9	von Willebrand factor	Homo sapiens	47-50
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	fibrinogen beta chain	Homo sapiens	203-213
1531588-6	1992	During digestion of fibrinogen at low plasmin concentration, up to 65% of the FpA was cleaved just subsequent to the progressive release of B beta-(1-42)-peptide, and the Arg-16-Gly-17 bond of the A alpha-chain became relatively stable towards plasmin action when present in fragment E (and possibly fragment Y).	Glycine	178-181	fibrinogen beta chain	Homo sapiens	20-30
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	thrombospondin 1	Homo sapiens	265-268
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	fibronectin 1	Homo sapiens	271-282
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	fibronectin 1	Homo sapiens	284-286
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	fibrinogen beta chain	Homo sapiens	215-217
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	von Willebrand factor	Homo sapiens	220-241
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	von Willebrand factor	Homo sapiens	243-246
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	thrombospondin 1	Homo sapiens	249-263
1281611-1	1992	A human urine serine proteinase chymotrypsin like hydrolyzes the peptide bonds: Phe-Ser (kinin); Gly-Gly, Leu-Arg, Phe-Lys (neuropeptides) and Gln-Gln (substance P).	Glycine	97-100	tachykinin precursor 1	Homo sapiens	152-163
1281611-1	1992	A human urine serine proteinase chymotrypsin like hydrolyzes the peptide bonds: Phe-Ser (kinin); Gly-Gly, Leu-Arg, Phe-Lys (neuropeptides) and Gln-Gln (substance P).	Glycine	101-104	tachykinin precursor 1	Homo sapiens	152-163
1316115-4	1992	Degradation of MeHg and EtHg with the myeloperoxidase (MPO)-H2O2-chloride system was inhibited by MPO inhibitors (cyanide and azide), catalase, hypochlorous acid (HOCI) scavengers (glycine, alanine, serine and taurine), 1,4-diazabicyclo[2,2,2]octane and 2,5-dimethylfuran, but not by hydroxyl radical scavengers (ethanol and mannitol).	Glycine	181-188	myeloperoxidase	Homo sapiens	38-53
1316115-4	1992	Degradation of MeHg and EtHg with the myeloperoxidase (MPO)-H2O2-chloride system was inhibited by MPO inhibitors (cyanide and azide), catalase, hypochlorous acid (HOCI) scavengers (glycine, alanine, serine and taurine), 1,4-diazabicyclo[2,2,2]octane and 2,5-dimethylfuran, but not by hydroxyl radical scavengers (ethanol and mannitol).	Glycine	181-188	myeloperoxidase	Homo sapiens	55-58
1731723-2	1992	Three members from another family with autosomal dominant retinitis pigmentosa showed a guanine-to-adenine transition mutation in the first nucleotide of codon 182 in the rhodopsin gene that resulted in a glycine to serine change.	Glycine	205-212	rhodopsin	Homo sapiens	171-180
1316115-4	1992	Degradation of MeHg and EtHg with the myeloperoxidase (MPO)-H2O2-chloride system was inhibited by MPO inhibitors (cyanide and azide), catalase, hypochlorous acid (HOCI) scavengers (glycine, alanine, serine and taurine), 1,4-diazabicyclo[2,2,2]octane and 2,5-dimethylfuran, but not by hydroxyl radical scavengers (ethanol and mannitol).	Glycine	181-188	myeloperoxidase	Homo sapiens	98-101
1284427-1	1992	The peptidyl diazomethanes Cbz-Gly-CHN2, Boc-Val-Gly-CHN2, H-Leu-Val-Gly-CHN2, Cbz-Leu-Val-Gly-CHN2 and Cbz-Arg-Leu-Val-Gly-CHN2, with peptidyl portions modelled after the proposed cysteine proteinase interacting N-terminal segment of human cystatin C, were synthesized.	Glycine	31-34	chimerin 2	Homo sapiens	35-39
1371492-4	1992	We used the peptide Trp-Thr-Val-Pro-Thr-Ala, WTVPTA (deduced from the complementary nucleotide sequence to that which codes for the Arg-Gly-Asp, RGD, domain in fibronectin), to test the immunologic activity of ITP sera.	Glycine	136-139	fibronectin 1	Homo sapiens	160-171
1730754-9	1992	These data establish 2 x RBD-Gly as a prevalent hnRNP protein structure across eukaryotes.	Glycine	29-32	heterogeneous nuclear ribonucleoprotein D like	Homo sapiens	48-53
1301191-4	1992	DNA sequence analysis of COL1A2 cDNAs demonstrated that the cysteine-containing chain resulted from a point mutation (G to T) in the first position of the codon for the glycine at residue 472 of the triple helical domain.	Glycine	169-176	collagen type I alpha 2 chain	Homo sapiens	25-31
1284427-7	1992	The high water-solubility of Cbz-Arg-Leu-Val-Gly-CHN2 allowing it to be dissolved to molar concentrations without use of non-physiological additives, makes it suitable for in vitro and in vivo cysteine proteinase inhibition studies.	Glycine	45-48	chimerin 2	Homo sapiens	49-53
1762917-1	1991	Zinc binding domains and the conserved Thr-Gly-Glu-Lys (TGEK) tetrapeptide in the N-terminal half of transcription factor IIIA (TFIIIA) were subjected to in vitro mutagenesis to biochemically assess their role in factor interaction with the 5S gene internal control region (ICR).	Glycine	43-46	general transcription factor IIIA	Homo sapiens	101-126
1542401-7	1992	These data suggest that the depression of the MSR was the result of a GABA-mediated pathway, while the facilitation of MSR involved both glycine and GABA.	Glycine	137-144	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	Homo sapiens	119-122
1304876-1	1992	The histidine-glycine-rich region of the light chain of cleaved high molecular weight kininogen (HK) is thought to be responsible for binding to negatively charged surfaces and initiation of the intrinsic coagulation, fibrinolytic, and kinin-forming systems.	Glycine	14-21	kininogen 1	Homo sapiens	64-95
1728638-5	1992	Pre-treatment of cells with 25-250 micrograms/ml of synthetic peptides containing the fibronectin cell-recognition sequence RGD (Arg-Gly-Asp) resulted in a concentration-dependent inhibition of fibronectin-mediated chemotaxis, whereas chemotaxis to collagen was not affected.	Glycine	133-136	fibronectin 1	Homo sapiens	86-97
1728638-5	1992	Pre-treatment of cells with 25-250 micrograms/ml of synthetic peptides containing the fibronectin cell-recognition sequence RGD (Arg-Gly-Asp) resulted in a concentration-dependent inhibition of fibronectin-mediated chemotaxis, whereas chemotaxis to collagen was not affected.	Glycine	133-136	fibronectin 1	Homo sapiens	194-205
1480089-3	1992	We have thus utilized this approach to alter the Col1a1 gene to encode amino acid substitutions in sequences around the known collagenase cleavage site (glycine-isoleucine at positions 775-776) in type I collagen, and transfect these genes into homozygous Mov-13 fibroblasts, in which the endogenous Col1a1 gene is inactive.	Glycine	153-160	collagen, type I, alpha 1	Mus musculus	49-55
1631048-5	1992	The contribution of the H49-54 fragment to the thrombin-inhibitor interaction was deduced by examining a series of analogs containing single glycine substitution and analogs with reduced number of residues within the linker.	Glycine	141-148	coagulation factor II, thrombin	Homo sapiens	47-55
1764061-4	1991	The presence of both bases predicts two SAA1 protein sequences, one having aspartic acid and the other glycine at position 72.	Glycine	103-110	serum amyloid A1	Homo sapiens	40-44
1762917-1	1991	Zinc binding domains and the conserved Thr-Gly-Glu-Lys (TGEK) tetrapeptide in the N-terminal half of transcription factor IIIA (TFIIIA) were subjected to in vitro mutagenesis to biochemically assess their role in factor interaction with the 5S gene internal control region (ICR).	Glycine	43-46	general transcription factor IIIA	Homo sapiens	128-134
1762917-6	1991	A Gly-dependent bend structure and a terminal positive charge in this tetrapeptide are important for TFIIIA interaction with DNA.	Glycine	2-5	general transcription factor IIIA	Homo sapiens	101-107
1687809-10	1991	A 168 bp insertion which codes for 56 amino acids corresponding to 7 extra uninterrupted repeats of proline-glycine rich octapeptide (PHGGGWGQ) was detected in the N terminal region of PrP gene.	Glycine	108-115	prion protein	Homo sapiens	185-188
1815830-1	1991	The localization of the glycine cleavage system was examined in the rat brain by immunohistochemistry using an antibody to P-protein (a constituent of the system).	Glycine	24-31	OCA2 melanosomal transmembrane protein	Rattus norvegicus	123-132
1839957-8	1991	Moreover, the attachment of IFN-gamma-treated Pam-T cells as well as non-treated cells to FN was blocked by the synthetic peptide Arg-Gly-Asp-Ser (RGDS), but not by the control peptide Arg-Gly-Glu-Ser.	Glycine	134-137	interferon gamma	Homo sapiens	28-37
1839957-8	1991	Moreover, the attachment of IFN-gamma-treated Pam-T cells as well as non-treated cells to FN was blocked by the synthetic peptide Arg-Gly-Asp-Ser (RGDS), but not by the control peptide Arg-Gly-Glu-Ser.	Glycine	134-137	fibronectin 1	Homo sapiens	29-31
1839957-8	1991	Moreover, the attachment of IFN-gamma-treated Pam-T cells as well as non-treated cells to FN was blocked by the synthetic peptide Arg-Gly-Asp-Ser (RGDS), but not by the control peptide Arg-Gly-Glu-Ser.	Glycine	189-192	interferon gamma	Homo sapiens	28-37
1839957-8	1991	Moreover, the attachment of IFN-gamma-treated Pam-T cells as well as non-treated cells to FN was blocked by the synthetic peptide Arg-Gly-Asp-Ser (RGDS), but not by the control peptide Arg-Gly-Glu-Ser.	Glycine	189-192	fibronectin 1	Homo sapiens	29-31
1819644-4	1991	The IgE antibodies of the patients bound most strongly and frequently to a unique protein with molecular weight of about 30,000 in the 7S-globulin fraction, which appeared to be the major allergen in soybeans and was named as Gly m Bd 30 K. The proteins in the 11S-globulin fraction were scarcely recognized by the patients" sera and assumed to be less allergenic for the patients with atopic dermatitis.	Glycine	226-229	immunoglobulin heavy constant epsilon	Homo sapiens	4-7
1939157-2	1991	Two forms of MGP were isolated from demineralization and urea extracts of bovine cortical bone, one 79 residues in length with the COOH terminus Phe-Arg-Gln and the other 83 residues in length with the COOH terminus Phe-Arg-Gln-Arg-Arg-Gly-Ala.	Glycine	236-239	matrix Gla protein	Bos taurus	13-16
1939204-11	1991	A comparison of the overlapping sequence between these two peptides suggests that this calmodulin binding site is localized in a 7-residue segment, 659Trp-Glu-Lys-Gly-Asn-Val-Phe665.	Glycine	163-166	calmodulin 1	Homo sapiens	87-97
1659210-7	1991	Inorganic anions transported by band 3, including Cl, NO3, and SO4, inhibited glycine transport.	Glycine	78-85	NBL1, DAN family BMP antagonist	Homo sapiens	54-57
1953667-0	1991	Substitution of cysteine for glycine-alpha 1-691 in the pro alpha 1(I) chain of type I procollagen in a proband with lethal osteogenesis imperfecta destabilizes the triple helix at a site C-terminal to the substitution.	Glycine	29-36	collagen type I alpha 2 chain	Homo sapiens	80-98
1953667-7	1991	Since the proteinase assay of helical stability generated a fragment of 700 residues that retained disulphide-bonded cysteine residues at alpha 1-691, the results provide one of the first indications that glycine substitutions in type I procollagen can alter the conformation of the triple helix at a site that is C-terminal to the site of the substitution.	Glycine	205-212	collagen type I alpha 2 chain	Homo sapiens	230-248
1797336-12	1991	This indicates that the MAO-B derived metabolites, glycineamide and glycine, contribute to the secretion of catecholamines as does milacemide itself.	Glycine	51-58	monoamine oxidase B	Bos taurus	24-29
1928099-6	1991	This residue occurs within a very highly conserved hydrophilic loop, is invariantly alanine or glycine in all ND1 proteins, and is adjacent to an invariant aspartic acid residue.	Glycine	95-102	mitochondrially encoded NADH dehydrogenase 1	Homo sapiens	110-113
1667689-6	1991	The major form of Anolis alpha-MSH is nonacetylated and has the following novel primary sequence: Ser-Tyr-Ala-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro(Val-amide).	Glycine	134-137	alpha-msh	Anolis carolinensis	25-34
1721615-6	1991	However, small proportions of the 23- and 19-kD molecules were not blocked, and their respective N-terminal sequences were found to correspond to Gly-40-Gly-27 and Pro29-Phe40 of human bFGF deduced from the cDNA sequence of a human hepatoma cell line, SK-HEP-1.	Glycine	146-149	fibroblast growth factor 2	Homo sapiens	185-189
1721615-6	1991	However, small proportions of the 23- and 19-kD molecules were not blocked, and their respective N-terminal sequences were found to correspond to Gly-40-Gly-27 and Pro29-Phe40 of human bFGF deduced from the cDNA sequence of a human hepatoma cell line, SK-HEP-1.	Glycine	153-156	fibroblast growth factor 2	Homo sapiens	185-189
1832087-6	1991	Treatment of the macrophages with glycine pH 3.0 buffer dissociated the conjugated TNF without affecting the integral membrane TNF.	Glycine	34-41	tumor necrosis factor	Mus musculus	83-86
1716370-4	1991	Unlike peptides related to Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val that bind to the fibrinogen receptor, this peptide binds to fibrinogen.	Glycine	59-62	fibrinogen beta chain	Homo sapiens	155-165
1920361-1	1991	The development of potent antithrombotic agents from the fibrinogen platelet receptor binding sequences Fg-alpha 572-575 -Arg-Gly-Asp-Ser- and Fg-gamma 400-411 -HHLGGAKQAGDV, believed to be a cryptic RGD-type sequence, is described.	Glycine	126-129	fibrinogen beta chain	Homo sapiens	57-67
1936592-7	1991	The biological significance of insulin-dependent gly-Pl hydrolysis was demonstrated by insulin and inositol phosphoglycan regulation of glucose metabolism in intact lymphocytes.	Glycine	49-52	insulin	Homo sapiens	31-38
1936592-7	1991	The biological significance of insulin-dependent gly-Pl hydrolysis was demonstrated by insulin and inositol phosphoglycan regulation of glucose metabolism in intact lymphocytes.	Glycine	49-52	insulin	Homo sapiens	87-94
1716370-4	1991	Unlike peptides related to Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val that bind to the fibrinogen receptor, this peptide binds to fibrinogen.	Glycine	31-34	fibrinogen beta chain	Homo sapiens	112-122
1716370-4	1991	Unlike peptides related to Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val that bind to the fibrinogen receptor, this peptide binds to fibrinogen.	Glycine	59-62	fibrinogen beta chain	Homo sapiens	112-122
1716370-4	1991	Unlike peptides related to Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val that bind to the fibrinogen receptor, this peptide binds to fibrinogen.	Glycine	59-62	fibrinogen beta chain	Homo sapiens	155-165
1716370-4	1991	Unlike peptides related to Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val that bind to the fibrinogen receptor, this peptide binds to fibrinogen.	Glycine	59-62	fibrinogen beta chain	Homo sapiens	112-122
1716370-4	1991	Unlike peptides related to Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val that bind to the fibrinogen receptor, this peptide binds to fibrinogen.	Glycine	59-62	fibrinogen beta chain	Homo sapiens	112-122
1716370-4	1991	Unlike peptides related to Arg-Gly-Asp-Ser and His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val that bind to the fibrinogen receptor, this peptide binds to fibrinogen.	Glycine	59-62	fibrinogen beta chain	Homo sapiens	155-165
1937565-7	1991	One site on the Fn molecule known to interact with phagocytic cells is the cell-binding domain containing the Arg-Gly-Asp (RGD) sequence.	Glycine	114-117	fibronectin 1	Homo sapiens	16-18
1801307-7	1991	DRB1*14.GB represents a DRB1*1402 variant whose sequence at codon 86 encodes valine (GTG) instead of glycine (GGT).	Glycine	101-108	major histocompatibility complex, class II, DR beta 1	Homo sapiens	0-4
1801307-7	1991	DRB1*14.GB represents a DRB1*1402 variant whose sequence at codon 86 encodes valine (GTG) instead of glycine (GGT).	Glycine	101-108	major histocompatibility complex, class II, DR beta 1	Homo sapiens	24-28
1881891-5	1991	The preferential V alpha 14-J alpha 281 expression seems to be due to positive selection because the V-J junctional region is always glycine, despite the ability of the V alpha 14 gene to associate with J alpha other than J alpha 281.	Glycine	133-140	T cell receptor alpha, variable 14	Mus musculus	17-27
1716636-1	1991	Site-directed mutagenesis studies have suggested that additional peptide information in the central cell-binding domain of fibronectin besides the minimal Arg-Gly-Asp (RGD) sequence is required for its full adhesive activity.	Glycine	159-162	fibronectin 1	Homo sapiens	123-134
1802238-3	1991	Analytical data of the degradation products showed that, in the case of AVP and [Sar7]AVP, there were two major sites of cleavage: Tyr-Phe and Arg-Gly.	Glycine	147-150	arginine vasopressin	Rattus norvegicus	72-75
1802238-3	1991	Analytical data of the degradation products showed that, in the case of AVP and [Sar7]AVP, there were two major sites of cleavage: Tyr-Phe and Arg-Gly.	Glycine	147-150	arginine vasopressin	Rattus norvegicus	86-89
1653659-2	1991	Albumin fractional synthetic rate was determined in five non-pregnant subjects and five normal pregnant subjects in late gestation after an overnight fast by simultaneous prime and intravenous infusion of two precursor amino acids, [15N]glycine and L-[1-13C]leucine, with additional priming of the large but, slowly turning over, urea pool with [15N2]urea.	Glycine	237-244	albumin	Homo sapiens	0-7
1874740-1	1991	Previous studies of adhesion mediated by the central cell-binding domain of fibronectin suggest that additional polypeptide information besides the Arg-Gly-Asp sequence is required for full activity.	Glycine	152-155	fibronectin 1	Homo sapiens	76-87
1720142-1	1991	Postembedding electron microscope immunocytochemistry of glycine and GABA conjugated to colloidal gold has been applied to pre-embedded cat retina stained with the antibody against tyrosine hydroxylase (Toh+).	Glycine	57-64	tyrosine hydroxylase	Homo sapiens	181-201
1874719-0	1991	Substitutions for glycine alpha 1-637 and glycine alpha 2-694 of type I procollagen in lethal osteogenesis imperfecta.	Glycine	42-49	collagen type I alpha 2 chain	Homo sapiens	65-83
1874719-2	1991	Two substitutions for glycine in the triple-helical domain were found in type I procollagen synthesized by skin fibroblasts from two probands with lethal osteogenesis imperfecta.	Glycine	22-29	collagen type I alpha 2 chain	Homo sapiens	73-91
1714722-2	1991	Results obtained from both peptide mapping and fast atom bombardment mass spectrometry indicate that tyrosine 67 in the sequence -Thr-Thr-His-Tyr67-Gly-Ser-Leu-Pro-Gln-Lys- in bovine MBP is the specific phosphorylation site.	Glycine	148-151	myelin basic protein	Bos taurus	183-186
1907272-0	1991	A highly conserved sequence of the Arg-Gly-Asp-binding domain of the integrin beta 3 subunit is sensitive to stimulation.	Glycine	39-42	integrin subunit beta 3	Homo sapiens	69-84
1907272-1	1991	The Arg-Gly-Asp (RGD)-binding domain of GPIIb-IIIa has been localized in a fragment of the GPIIIa subunit that includes the sequence between amino acids 109 and 171.	Glycine	8-11	integrin subunit beta 3	Homo sapiens	91-97
1653659-7	1991	The amount of albumin synthesized in the intravascular compartment was significantly greater at 8.8 and 9.5 g/day in pregnant subjects compared with 6.4 and 6.3 g/day in non-pregnant control subjects (glycine and leucine methods, respectively).	Glycine	201-208	albumin	Homo sapiens	14-21
1905729-6	1991	Extensive digestion of rhoA p21 with Achromobacter protease I yielded a C-terminal peptide, Ser-Gly-Cys190, that lacked the three C-terminal amino acids predicted from the cDNA but was geranylgeranylated and carboxyl methylated at the cysteine residue.	Glycine	96-99	ras homolog family member A	Bos taurus	23-27
2069556-0	1991	Glycine-extended processing intermediate of proVIP: a new form of VIP in the rat.	Glycine	0-7	vasoactive intestinal peptide	Rattus norvegicus	47-50
2069556-1	1991	The biosynthesis of many peptides including vasoactive intestinal polypeptide (VIP) requires enzymatic alpha-carboxyamidation via a glycine-extended intermediate form.	Glycine	132-139	vasoactive intestinal peptide	Rattus norvegicus	44-77
2069556-1	1991	The biosynthesis of many peptides including vasoactive intestinal polypeptide (VIP) requires enzymatic alpha-carboxyamidation via a glycine-extended intermediate form.	Glycine	132-139	vasoactive intestinal peptide	Rattus norvegicus	79-82
2069556-2	1991	In an effort to identify and quantify glycine-extended VIP in rat tissue extracts a radio-immunoassay specific for this peptide was developed.	Glycine	38-45	vasoactive intestinal peptide	Rattus norvegicus	55-58
2069556-3	1991	The concentrations of glycine-extended VIP ranged from 1.3 pmol/g in the brain to 83.9 pmol/g in the small intestine.	Glycine	22-29	vasoactive intestinal peptide	Rattus norvegicus	39-42
2069556-5	1991	The ratio of glycine-extended VIP to amidated VIP varied considerably being highest (63%) in the small intestine.	Glycine	13-20	vasoactive intestinal peptide	Rattus norvegicus	30-33
2069556-6	1991	The natural occurrence of glycine-extended VIP in connection with our recent demonstration of its biological activity suggest a physiological role for this biosynthetic intermediate VIP form.	Glycine	26-33	vasoactive intestinal peptide	Rattus norvegicus	43-46
2069556-6	1991	The natural occurrence of glycine-extended VIP in connection with our recent demonstration of its biological activity suggest a physiological role for this biosynthetic intermediate VIP form.	Glycine	26-33	vasoactive intestinal peptide	Rattus norvegicus	182-185
1783488-0	1991	Aminopeptidase resistant Arg-Gly-Asp analogs are stable in plasma and inhibit platelet aggregation.	Glycine	29-32	carboxypeptidase Q	Homo sapiens	0-14
2071595-6	1991	The main collagenous region of the alpha 1(V) chain consisted of 338 repeats of Gly-X-Y-triplet.	Glycine	80-83	collagen type V alpha 1 chain	Homo sapiens	35-45
1905729-6	1991	Extensive digestion of rhoA p21 with Achromobacter protease I yielded a C-terminal peptide, Ser-Gly-Cys190, that lacked the three C-terminal amino acids predicted from the cDNA but was geranylgeranylated and carboxyl methylated at the cysteine residue.	Glycine	96-99	ras homolog family member A	Bos taurus	28-31
2043162-1	1991	The anticonvulsant drug milacemide (2-n-pentylaminoacetamide) is known to be oxidized by monoamine oxidase-B to yield glycinamide which then breaks-down to give glycine.	Glycine	161-168	monoamine oxidase B	Mus musculus	89-108
1854346-10	1991	The N-terminus of the larger intermediate, PP2C, was Gly-12, whereas the N-terminus of the smaller, PP2D, was His-21.	Glycine	53-56	protein phosphatase 1 (formerly 2C)-like	Mus musculus	43-47
2035536-6	1991	The results here confirm previous indications that the effects of glycine substitutions in type I procollagen are highly position specific.	Glycine	66-73	collagen type I alpha 2 chain	Homo sapiens	91-109
2055204-3	1991	We have studied the processing of a C-peptide-deleted precursor of neuropeptide Y (NPY) in which the precursor terminates in the sequence Gly-Lys-Arg and does not require any dibasic specific endoproteolytic processing.	Glycine	138-141	pro-neuropeptide Y	Cricetulus griseus	67-81
2055204-3	1991	We have studied the processing of a C-peptide-deleted precursor of neuropeptide Y (NPY) in which the precursor terminates in the sequence Gly-Lys-Arg and does not require any dibasic specific endoproteolytic processing.	Glycine	138-141	pro-neuropeptide Y	Cricetulus griseus	83-86
1938100-3	1991	Substitution of the Arg residue occupying position 2 of [Sar1,Ile8]ANG II (pA2 8.1) by Gly, Ala, Nle, Phe, Pro or Sar reduced the antagonist potency to pA2 = 7.0, 6.8, 6.7, 6.8, 5.8 and 5.3, respectively.	Glycine	87-90	angiotensinogen	Rattus norvegicus	67-73
2035536-0	1991	A single base mutation in type I procollagen (COL1A1) that converts glycine alpha 1-541 to aspartate in a lethal variant of osteogenesis imperfecta: detection of the mutation with a carbodiimide reaction of DNA heteroduplexes and direct sequencing of products of the PCR.	Glycine	68-75	collagen type I alpha 2 chain	Homo sapiens	26-44
1903394-1	1991	The assembly of fibronectin into disulfide cross-linked extracellular matrices requires the interaction of mesenchymal cells with two distinct sites on fibronectin, the Arg-Gly-Asp cell adhesive site and an amino-terminal site contained within the first five type I homologous repeats (Quade, B. J., and McDonald, J.	Glycine	173-176	fibronectin 1	Homo sapiens	16-27
1674522-8	1991	Inasmuch as the 140-kDa fragment of TSP contains an Arg-Gly-Asp sequence similar to the cell recognition site of FN and VN, we determined whether RGDS peptides would inhibit PMN adhesion.	Glycine	56-59	thrombospondin 1	Homo sapiens	36-39
1865818-4	1991	In nine additional subjects, the fractional synthetic rate (FSR) of fibronectin was calculated during a 24-hour infusion using urinary hippurate and plasma alpha-ketoisocaproic acid enrichment to represent the precursors for incorporation of labeled glycine and leucine, respectively, into fibronectin.	Glycine	250-257	fibronectin 1	Homo sapiens	68-79
2066103-4	1991	These data confirm that individuals with nonlethal OI may commonly harbor defects in the COL1A2 gene, and suggest that many of the defects are substitutions for glycine residues in the alpha 2(I) triple helical domain.	Glycine	161-168	collagen type I alpha 2 chain	Homo sapiens	89-95
1673992-13	1991	Additional adhesion assays performed in the presence of a pentapeptide containing the amino acid sequence arg-gly-asp (RGD), which is part of one of the cell-binding domains of FN, demonstrated that the RGD-containing peptide almost totally blocked the phorbol ester-induced adhesion of U937 cells to FN.	Glycine	110-113	fibronectin 1	Homo sapiens	177-179
1673992-13	1991	Additional adhesion assays performed in the presence of a pentapeptide containing the amino acid sequence arg-gly-asp (RGD), which is part of one of the cell-binding domains of FN, demonstrated that the RGD-containing peptide almost totally blocked the phorbol ester-induced adhesion of U937 cells to FN.	Glycine	110-113	fibronectin 1	Homo sapiens	301-303
2052556-8	1991	Absence in the normal population, tight linkage with phenotypic expression of disease, and absence of any additional abnormality of GP Ib alpha in these patients identify the glycine-to-valine substitution as a point mutation underlying functional abnormality of the vWF receptor in PT-vWD.	Glycine	175-182	von Willebrand factor	Homo sapiens	267-270
1903394-1	1991	The assembly of fibronectin into disulfide cross-linked extracellular matrices requires the interaction of mesenchymal cells with two distinct sites on fibronectin, the Arg-Gly-Asp cell adhesive site and an amino-terminal site contained within the first five type I homologous repeats (Quade, B. J., and McDonald, J.	Glycine	173-176	fibronectin 1	Homo sapiens	152-163
2051722-8	1991	The cytoprotective effect of glycine in the mTAL of perfused kidneys, shared with l-alanine, appears to be relatively specific for these amino acids and probably unrelated to a diminution in cell work.	Glycine	29-36	talipes	Mus musculus	44-48
1871720-8	1991	Both vWf binding and platelet adhesion to sulfatides can be inhibited by the sulfated polysaccharide dextran sulfate at low concentration, fucoidan at high concentrations, but not by heparin, fibrinogen, fibronectin, or the synthetic peptides Gly-Arg-Gly-Asp-Ser-Pro or Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	251-254	von Willebrand factor	Homo sapiens	5-8
1871720-8	1991	Both vWf binding and platelet adhesion to sulfatides can be inhibited by the sulfated polysaccharide dextran sulfate at low concentration, fucoidan at high concentrations, but not by heparin, fibrinogen, fibronectin, or the synthetic peptides Gly-Arg-Gly-Asp-Ser-Pro or Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	251-254	von Willebrand factor	Homo sapiens	5-8
2051722-1	1991	The addition of 2 mM glycine to the recirculating perfusate of isolated perfused rat kidneys almost completely prevented the severe morphological injury to tubular cells lining the medullary thick ascending limb (mTAL) that normally develops in this preparation.	Glycine	21-28	talipes	Mus musculus	213-217
2051722-2	1991	Glycine was similarly effective in reducing mTAL injury associated with hypoxic perfusion, indomethacin and amphotericin.	Glycine	0-7	talipes	Mus musculus	44-48
1645541-2	1991	The reaction of GlyPro with sulfite in the presence of Co(II) or peroxidase/H2O2 led to Gly liberation, suggesting the oxidative cleavage of protein at Pro residues.	Glycine	16-19	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	55-61
1871715-2	1991	In a one-step procedure F XIII is activated by thrombin and Ca2+ and cross-links glycine-ethylester to a specific glutamine containing peptide substrate.	Glycine	81-88	coagulation factor II, thrombin	Homo sapiens	47-55
1871720-8	1991	Both vWf binding and platelet adhesion to sulfatides can be inhibited by the sulfated polysaccharide dextran sulfate at low concentration, fucoidan at high concentrations, but not by heparin, fibrinogen, fibronectin, or the synthetic peptides Gly-Arg-Gly-Asp-Ser-Pro or Gly-Arg-Gly-Glu-Ser-Pro.	Glycine	243-246	von Willebrand factor	Homo sapiens	5-8
2007607-13	1991	We propose a model for the structure of loricrin in which (i) the unusual glycine-serine-rich sequences adopt a flexible loop conformation, indexed on the recurrent aliphatic residues; (ii) inter- or intramolecular isodipeptide and disulfide cross-links induce or stabilize folding of loricrin so as to form a more compact rosette-like structure; and (iii) the presence of the flexible glycine-rich loops necessarily will impact a flexible character to the cell envelope and entire epithelium.	Glycine	74-81	loricrin cornified envelope precursor protein	Homo sapiens	40-48
2007607-13	1991	We propose a model for the structure of loricrin in which (i) the unusual glycine-serine-rich sequences adopt a flexible loop conformation, indexed on the recurrent aliphatic residues; (ii) inter- or intramolecular isodipeptide and disulfide cross-links induce or stabilize folding of loricrin so as to form a more compact rosette-like structure; and (iii) the presence of the flexible glycine-rich loops necessarily will impact a flexible character to the cell envelope and entire epithelium.	Glycine	386-393	loricrin cornified envelope precursor protein	Homo sapiens	40-48
1706753-3	1991	Single nucleotide substitutions in the HA genes of mutant viruses identified both novel and immunodominant antigenic sites on the HA1 subunit: a majority of mAbs, from different donors, were of the IgG2a isotype and were specific for HA1 158 Gly.	Glycine	242-245	Rho GTPase activating protein 45	Mus musculus	130-133
1674365-8	1991	Two differences were found in the c-met coding region with respect to the published human c-met cDNA: (1) the lack of 54 nucleotides corresponding to a stretch of 18 amino acids located in the extracellular domain of the receptor, and (2) the substitution of the codon specifying alanine 1209 (located in the tyrosine kinase domain) with one coding for glycine.	Glycine	353-360	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	34-39
1825316-2	1991	125I-labeled fibronectin was inhibited from binding to the fungus by unlabeled human plasma fibronectin and by Arg-Gly-Asp (RGD), Gly-Arg-Gly-Glu-Ser-Pro (GRGESP), and Gly-Arg-Gly-Asp-Thr-Pro (GRGDTP), but binding was not inhibited by Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	115-118	fibronectin 1	Homo sapiens	13-24
1826081-11	1991	These results demonstrate that the high-affinity 67 kDa laminin receptor previously identified in a range of normal and transformed cells and its complementary Tyr-Ile-Gly-Ser-Arg binding domain play an important role in the interaction of platelets with laminin.	Glycine	168-171	ribosomal protein SA	Homo sapiens	49-72
2022700-9	1991	The rates of glycine incorporation into porphyrin and heme in Belgrade reticulocytes incubated with Fe2-transferrin or Fe-SIH paralleled the rates of iron incorporation into heme.	Glycine	13-20	transferrin	Rattus norvegicus	104-115
1672107-5	1991	We found that the major component of GSS amyloid is an 11 kd degradation product of PrP, whose N-terminus corresponds to the glycine residue at position 58 of the amino acid sequence deduced from the human PrP cDNA.	Glycine	125-132	prion protein	Homo sapiens	84-87
1672107-5	1991	We found that the major component of GSS amyloid is an 11 kd degradation product of PrP, whose N-terminus corresponds to the glycine residue at position 58 of the amino acid sequence deduced from the human PrP cDNA.	Glycine	125-132	prion protein	Homo sapiens	206-209
1672107-8	1991	The N-terminal cleavage of PrP in GSS disease occurs at a tryptophan-glycine peptide bond identical to that cleaved by proteinase K in vitro to generate PrP 27-30 from hamster PrPSc at codon 90.	Glycine	69-76	prion protein	Homo sapiens	27-30
1825316-2	1991	125I-labeled fibronectin was inhibited from binding to the fungus by unlabeled human plasma fibronectin and by Arg-Gly-Asp (RGD), Gly-Arg-Gly-Glu-Ser-Pro (GRGESP), and Gly-Arg-Gly-Asp-Thr-Pro (GRGDTP), but binding was not inhibited by Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	130-133	fibronectin 1	Homo sapiens	13-24
1825316-2	1991	125I-labeled fibronectin was inhibited from binding to the fungus by unlabeled human plasma fibronectin and by Arg-Gly-Asp (RGD), Gly-Arg-Gly-Glu-Ser-Pro (GRGESP), and Gly-Arg-Gly-Asp-Thr-Pro (GRGDTP), but binding was not inhibited by Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	130-133	fibronectin 1	Homo sapiens	13-24
1825316-2	1991	125I-labeled fibronectin was inhibited from binding to the fungus by unlabeled human plasma fibronectin and by Arg-Gly-Asp (RGD), Gly-Arg-Gly-Glu-Ser-Pro (GRGESP), and Gly-Arg-Gly-Asp-Thr-Pro (GRGDTP), but binding was not inhibited by Gly-Arg-Gly-Asp-Ser-Pro.	Glycine	130-133	fibronectin 1	Homo sapiens	13-24
2017368-3	1991	A partial revertant TrpA phenotype can be obtained from trpA218 by changing either Leu22 back to Phe or Ser211 back to Gly.	Glycine	119-122	tryptase gamma 1	Homo sapiens	20-24
2067980-6	1991	Two amino acid differences were detected at position 1, with Gly in rabbit CGRP instead of Ala in human CGRP-II, and at position 35, with Glu instead of Lys, respectively.	Glycine	61-64	calcitonin related polypeptide beta	Homo sapiens	104-111
1750929-10	1991	The minimal active sequence within CS5, the tetrapeptide Arg-Glu-Asp-Val (REDV), is somewhat related to the Arg-Gly-Asp-Ser (RGDS) sequence that represents a major active site in the central cell-binding domain (CCBD) of fibronectin.	Glycine	112-115	chorionic somatomammotropin hormone like 1	Homo sapiens	35-38
2045450-3	1991	Microsequence analysis showed that both proteins have the same N-terminal sequence Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe..., which is identical with that of (1-146) bFGF extracted from human brain.	Glycine	107-110	fibroblast growth factor 2	Homo sapiens	175-179
2045450-3	1991	Microsequence analysis showed that both proteins have the same N-terminal sequence Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe..., which is identical with that of (1-146) bFGF extracted from human brain.	Glycine	111-114	fibroblast growth factor 2	Homo sapiens	175-179
2045450-3	1991	Microsequence analysis showed that both proteins have the same N-terminal sequence Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe..., which is identical with that of (1-146) bFGF extracted from human brain.	Glycine	111-114	fibroblast growth factor 2	Homo sapiens	175-179
1864844-9	1991	In conclusion, triflavin specifically binds to fibrinogen receptor associated with GP IIb/IIIa complex and its binding site is located at or near GP IIb/IIIa complex, overlapping with those of 7E3 and another Arg-Gly-Asp-containing polypeptide, rhodostomin.	Glycine	213-216	fibrinogen beta chain	Homo sapiens	47-57
1993703-2	1991	Several cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone.	Glycine	55-62	myosin binding protein H like	Gallus gallus	23-32
1993705-8	1991	Glycine decarboxylase mRNA levels show a linear relationship with H-protein mRNA levels and with specific activities of the glycine cleavage reaction in active tissues.	Glycine	124-131	glycine decarboxylase	Gallus gallus	0-21
1993705-9	1991	Tissue-specific distribution of the glycine cleavage activity is primarily determined by the expression of the glycine decarboxylase gene.	Glycine	36-43	glycine decarboxylase	Gallus gallus	111-132
1846881-4	1991	Sequence analysis presented in this report reveals that this partial BP180 cDNA encodes two protein domains which have primary structures that are characteristic of the triple helical domains of collagens, i.e., glycine appears at every third position and over one-third of the remaining residues are proline.	Glycine	212-219	collagen type XVII alpha 1 chain	Homo sapiens	69-74
1703153-11	1991	The combination of heparin and Arg-Gly-Asp-Ser inhibited G361 attachment to TSP.	Glycine	35-38	thrombospondin 1	Homo sapiens	76-79
1668266-7	1991	The catalytic activity of recombinant angiotensin-converting enzyme, in terms of angiotensin I and 2-furanacryloyl-Phe-Gly-Gly hydrolysis, chloride activation, and lisinopril inhibition, was essentially identical to that of the native enzyme.	Glycine	119-122	angiotensin-converting enzyme	Cricetulus griseus	38-67
1846556-5	1991	Third-position substitutions have less of an effect on NAT activity with glycine, aspartic acid, glutamic acid, and tryptophan being most inhibiting (with N-terminal Ser-Tyr).	Glycine	73-80	N-acetyltransferase 1	Rattus norvegicus	55-58
1685408-2	1991	A soluble human brain aminopeptidase which hydrolyses the Tyr-Gly bond of Met-enkephalin and Leu-enkephalin was identified in the brains of the following vertebrates: mammals (Callithrix jacchus and Rattus norvegicus), bird (Gallus domesticus), reptile (Tupinambis teguixin), amphibia (Bufo paracnemis), fish (Sarotherdon niloticus) and elasmobranchy (Galeocerdo cuvieri).	Glycine	62-65	carboxypeptidase Q	Homo sapiens	22-36
1820039-2	1991	A recombinant alpha-amidating enzyme was used to convert the glycine-extended precursor, GRF(1-44)-Gly-OH, to GRF(1-44)-NH2 in an essentially quantitative fashion.	Glycine	61-68	growth hormone releasing hormone	Homo sapiens	89-92
1820039-2	1991	A recombinant alpha-amidating enzyme was used to convert the glycine-extended precursor, GRF(1-44)-Gly-OH, to GRF(1-44)-NH2 in an essentially quantitative fashion.	Glycine	61-68	growth hormone releasing hormone	Homo sapiens	110-113
1820039-2	1991	A recombinant alpha-amidating enzyme was used to convert the glycine-extended precursor, GRF(1-44)-Gly-OH, to GRF(1-44)-NH2 in an essentially quantitative fashion.	Glycine	99-105	growth hormone releasing hormone	Homo sapiens	89-92
1820039-2	1991	A recombinant alpha-amidating enzyme was used to convert the glycine-extended precursor, GRF(1-44)-Gly-OH, to GRF(1-44)-NH2 in an essentially quantitative fashion.	Glycine	99-105	growth hormone releasing hormone	Homo sapiens	110-113
1685408-2	1991	A soluble human brain aminopeptidase which hydrolyses the Tyr-Gly bond of Met-enkephalin and Leu-enkephalin was identified in the brains of the following vertebrates: mammals (Callithrix jacchus and Rattus norvegicus), bird (Gallus domesticus), reptile (Tupinambis teguixin), amphibia (Bufo paracnemis), fish (Sarotherdon niloticus) and elasmobranchy (Galeocerdo cuvieri).	Glycine	62-65	proopiomelanocortin	Homo sapiens	74-88
2045542-3	1991	Both sVT and sIT precursors were found to contain a signal peptide and hormone that is connected to a neurophysin by a Gly-Lys-Arg sequence.	Glycine	119-122	signaling threshold regulating transmembrane adaptor 1	Homo sapiens	13-16
1802033-0	1991	An Escherichia coli protein with homology to the H-protein of the glycine cleavage enzyme complex from pea and chicken liver.	Glycine	66-73	glycine cleavage system protein H	Gallus gallus	49-58
1802033-1	1991	The nucleotide sequence of an Escherichia coli gene which presumably encodes the H-protein of the glycine cleavage (GCV) enzyme complex is presented.	Glycine	98-105	glycine cleavage system protein H	Gallus gallus	81-90
2026461-7	1991	The DRB1 second exon sequence of DRB1*04.CB is identical to DRB1*0405 except at codon 86 where GTG encodes valine instead of GGT encoding glycine.	Glycine	138-145	major histocompatibility complex, class II, DR beta 1	Homo sapiens	4-8
2026461-7	1991	The DRB1 second exon sequence of DRB1*04.CB is identical to DRB1*0405 except at codon 86 where GTG encodes valine instead of GGT encoding glycine.	Glycine	138-145	major histocompatibility complex, class II, DR beta 1	Homo sapiens	33-37
2026461-7	1991	The DRB1 second exon sequence of DRB1*04.CB is identical to DRB1*0405 except at codon 86 where GTG encodes valine instead of GGT encoding glycine.	Glycine	138-145	major histocompatibility complex, class II, DR beta 1	Homo sapiens	33-37
1988465-0	1991	An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion.	Glycine	7-10	coagulation factor II, thrombin	Homo sapiens	31-39
2260977-7	1990	The alpha-MSH sequence is C-terminally flanked by the Gly-Lys-Lys amidation signal while the joining peptide is not amidate.	Glycine	54-57	proopiomelanocortin	Homo sapiens	10-13
1725860-6	1991	Absence of the two and four cysteines in the N-terminal region in the human and rat IGFBP-6 resulted in the deletion of the invariant Gly-Cys-Gly-Cys-Cys sequence which is present in all the other five IGFBPs.	Glycine	134-137	insulin-like growth factor binding protein 6	Rattus norvegicus	84-91
1725860-6	1991	Absence of the two and four cysteines in the N-terminal region in the human and rat IGFBP-6 resulted in the deletion of the invariant Gly-Cys-Gly-Cys-Cys sequence which is present in all the other five IGFBPs.	Glycine	142-145	insulin-like growth factor binding protein 6	Rattus norvegicus	84-91
1871556-0	1991	Vasopressin and cortisol levels in response to glycine infusion.	Glycine	47-54	arginine vasopressin	Homo sapiens	0-11
1871556-4	1991	These results suggest that a glycine solution has water-retaining properties by stimulating the vasopressin secretion but usually not by increasing cortisol secretion.	Glycine	29-36	arginine vasopressin	Homo sapiens	96-107
2259385-8	1990	This mutation leads to substitution of aspartic acid for glycine in one of the regions identified as a frequent target of point mutations in p53.	Glycine	57-64	tumor protein p53	Homo sapiens	141-144
2082193-1	1990	An abnormal human thyroid hormone beta-receptor (hTR beta-Mf), which has a glycine to arginine substitution in the hormone-binding domain, has been identified in affected members of one family with generalized resistance to thyroid hormone.	Glycine	75-82	telomerase RNA component	Homo sapiens	49-52
2243383-10	1990	This hypothesis was supported by cell-free translation of mutant L1R transcripts in which the penultimate glycine codon had been altered by site-directed mutagenesis to encode either an aspartic acid (pL1D1) or alanine (pL1A1) residue.	Glycine	106-113	IMV membrane protein	Vaccinia virus	65-68
2093214-7	1990	These data show that the flexor reflex afferents and the larger diameter afferents alter the MSR solely through glycine-mediated post-synaptic inhibition.	Glycine	112-119	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	Homo sapiens	93-96
2211640-0	1990	cDNA sequence, in vitro synthesis, and intramitochondrial lipoylation of H-protein of the glycine cleavage system.	Glycine	90-97	myosin binding protein H like	Gallus gallus	73-82
1978725-0	1990	A substitution at a non-glycine position in the triple-helical domain of pro alpha 2(I) collagen chains present in an individual with a variant of the Marfan syndrome.	Glycine	24-31	collagen type I alpha 2 chain	Homo sapiens	77-96
1978725-1	1990	A substitution for a highly conserved non-glycine residue in the triple-helical domain of the pro alpha 2(I) collagen molecule was found in an individual with a variant of the Marfan syndrome.	Glycine	42-49	collagen type I alpha 2 chain	Homo sapiens	98-117
2271648-3	1990	PSG9 and PSG10 are representatives of two distinct classes of PSG protein that have N-termini with or without the Arg-Gly-Asp motif implicated in adhesion.	Glycine	118-121	pregnancy specific beta-1-glycoprotein 5	Homo sapiens	0-3
2211640-1	1990	H-protein is a component of the glycine cleavage system loosely associated with the mitochondrial inner membrane and has lipoic acid as a prosthetic group.	Glycine	32-39	myosin binding protein H like	Gallus gallus	0-9
2176839-0	1990	Glycine-231 residue of the mouse mitochondrial protonmotive cytochrome b: mutation to aspartic acid deranges electron transport.	Glycine	0-7	cytochrome b, mitochondrial	Mus musculus	60-72
2123470-2	1990	An arginine for glycine substitution in apolipoprotein A-I identified in the proband"s amyloid fibrils was determined to be the result of a mutation of guanine to cytosine in the apolipoprotein A-I gene at the position corresponding to the first base of codon 26.	Glycine	16-23	apolipoprotein A1	Homo sapiens	40-58
2123470-2	1990	An arginine for glycine substitution in apolipoprotein A-I identified in the proband"s amyloid fibrils was determined to be the result of a mutation of guanine to cytosine in the apolipoprotein A-I gene at the position corresponding to the first base of codon 26.	Glycine	16-23	apolipoprotein A1	Homo sapiens	179-197
1698903-3	1990	There was also inhibition of the agglutination of the M-positive cells with anti-M antibody by the synthesized octapeptide (Ser-Ser-Thr-Thr-Gly-Val-Ala-Met) from the M-amino terminus of glycophorin A.	Glycine	140-143	glycophorin A (MNS blood group)	Homo sapiens	186-199
1976733-5	1990	This leads, at the translation level, to the substitution of an arginine residue (positively charged) in C3 S for a glycine residue (neutral) in C3 F.	Glycine	116-123	lysophosphatidylcholine acyltransferase 3	Homo sapiens	145-149
2118516-5	1990	The catabolic OTCase lost most of its homotropic cooperativity and gained anabolic activity when an amino acid residue near the CP binding site, Glu-106, was replaced by alanine or glycine.	Glycine	181-188	ornithine carbamoyltransferase	Escherichia coli	14-20
2369894-4	1990	These same single amino acid substitutions enhanced the affinity of the thrombomodulin-thrombin complex for the substrate at 3 mM calcium 3-(Gly-substitution) to 6-(Phe-substitution) fold, either without influencing kcat (Gly-substitution) or with a 2.5-fold decrease of kcat.	Glycine	141-144	coagulation factor II, thrombin	Homo sapiens	87-95
2390089-5	1990	The RYD sequence of streptavidin thus mimics RGD (Arg-Gly-Asp), the universal recognition domain present in fibronectin and other adhesion-related molecules.	Glycine	54-57	fibronectin 1	Homo sapiens	108-119
2116413-0	1990	Mutations that substitute serine for glycine alpha 1-598 and glycine alpha 1-631 in type I procollagen.	Glycine	61-68	collagen type I alpha 2 chain	Homo sapiens	84-102
2369894-4	1990	These same single amino acid substitutions enhanced the affinity of the thrombomodulin-thrombin complex for the substrate at 3 mM calcium 3-(Gly-substitution) to 6-(Phe-substitution) fold, either without influencing kcat (Gly-substitution) or with a 2.5-fold decrease of kcat.	Glycine	222-225	coagulation factor II, thrombin	Homo sapiens	87-95
1972721-7	1990	VLA-5-dependent binding to FN but not costimulation by FN can be specifically blocked with peptides containing the RGD (arg-gly-asp) tripeptide sequence whereas VLA-4-dependent binding and costimulation can both be efficiently inhibited by a 12 amino acid peptide, LHGPEILDVPST (leu-his-gly-pro-glu-iso-leu-asp-val-pro-ser-thr), derived from the alternatively spliced IIICS region of FN.	Glycine	124-127	integrin subunit alpha 5	Homo sapiens	0-5
1697752-5	1990	Other features deduced from the bovine IGFBP-2 cDNA include: an abundance of leucine in the pre-peptide, an Arg-Gly-Asp sequence, absence of N-linked glycosylation sites, and an imperfect polyadenylation signal as well as an ATTTA motif in the 3" non-coding DNA.	Glycine	112-115	insulin like growth factor binding protein 2	Bos taurus	39-46
2275749-1	1990	We have synthesized an insulin-like compound, consisting of the B-chain of bovine insulin and an A-chain corresponding to the A-domain of human insulin-like growth factor-I (IGF-I), in which the isoleucine residue normally present in position 2 of the A-domain of IGF-I has been replaced with glycine.	Glycine	293-300	insulin like growth factor 1	Homo sapiens	144-172
2275749-1	1990	We have synthesized an insulin-like compound, consisting of the B-chain of bovine insulin and an A-chain corresponding to the A-domain of human insulin-like growth factor-I (IGF-I), in which the isoleucine residue normally present in position 2 of the A-domain of IGF-I has been replaced with glycine.	Glycine	293-300	insulin like growth factor 1	Homo sapiens	174-179
1696474-1	1990	The synthetic phosphotyrosyl tridecapeptide H-Arg-Leu-Ile-Glu-Asp-Asn-Glu-Tyr(P)-Thr-Ala-Arg-Gln-Gly-OH, reproducing a major phosphoacceptor site of protein tyrosine kinases of the src-family, can be phosphorylated at Thr-9 by both casein kinases -1 and -2.	Glycine	97-100	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	181-184
2369430-5	1990	Relative risk was also associated with DR1.1, the common white DR1 (Dw1) type, which has a third hypervariable region amino acid sequence similar to some forms of DR4 and has glycine at position 86.	Glycine	175-182	WD repeat domain 11	Homo sapiens	39-44
2114233-0	1990	Acceleration of recombinant tissue-type plasminogen activator-induced thrombolysis and prevention of reocclusion by the combination of heparin and the Arg-Gly-Asp-containing peptide bitistatin in a canine model of coronary thrombosis.	Glycine	155-158	tissue-type plasminogen activator	Canis lupus familiaris	28-61
2115046-2	1990	The quantitative response of TRH-Gly-stimulated PRL, TSH, and GH was evaluated in nine patients with anorexia nervosa, six age-matched normal women, eight patients with uremia, five patients with acromegaly, and two patients with prolactinoma.	Glycine	33-36	prolactin	Homo sapiens	48-51
1972721-7	1990	VLA-5-dependent binding to FN but not costimulation by FN can be specifically blocked with peptides containing the RGD (arg-gly-asp) tripeptide sequence whereas VLA-4-dependent binding and costimulation can both be efficiently inhibited by a 12 amino acid peptide, LHGPEILDVPST (leu-his-gly-pro-glu-iso-leu-asp-val-pro-ser-thr), derived from the alternatively spliced IIICS region of FN.	Glycine	124-127	fibronectin 1	Homo sapiens	27-29
1693626-0	1990	Isolation of a novel integrin receptor mediating Arg-Gly-Asp-directed cell adhesion to fibronectin and type I collagen from human neuroblastoma cells.	Glycine	53-56	fibronectin 1	Homo sapiens	87-98
2163679-1	1990	Various gastrin analogues and CCK-8 (Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2) are hydrolyzed in vitro by angiotensin-converting enzyme (ACE), the main and initial cleavage occurring at the Met-Asp (or Leu-Asp) bond, releasing the C-terminal dipeptide amide Asp-Phe-NH2.	Glycine	55-58	angiotensin I converting enzyme	Rattus norvegicus	107-136
2163679-1	1990	Various gastrin analogues and CCK-8 (Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2) are hydrolyzed in vitro by angiotensin-converting enzyme (ACE), the main and initial cleavage occurring at the Met-Asp (or Leu-Asp) bond, releasing the C-terminal dipeptide amide Asp-Phe-NH2.	Glycine	55-58	angiotensin I converting enzyme	Rattus norvegicus	138-141
2374004-5	1990	The CP produced by proteolytic cleavage at the Arg/Gly site between residues 680 and 681 contains 504 amino acids (Mr 56019) and has hydrophobic properties.	Glycine	51-54	golgi phosphoprotein 3	Homo sapiens	4-6
2374004-6	1990	The Arg/Gly cleavage site deduced by N-terminal amino acid sequence analysis is the first for a nepovirus coat protein and for plant viruses expressing their genomic RNAs by polyprotein synthesis.	Glycine	8-11	golgi phosphoprotein 3	Homo sapiens	106-118
1693626-1	1990	Association of a novel beta 1-related subunit with alpha v. We report the isolation from two human neuroblastoma cell lines of an Arg-Gly-Asp-dependent integrin complex capable of binding to vitronectin, fibronectin, and type I collagen.	Glycine	134-137	fibronectin 1	Homo sapiens	204-215
2185035-1	1990	The calcium-binding protein calbindin D9k has previously been shown to exist in two folded forms only differing in the proline cis-trans isomerism of the Gly-42-Pro-43 amide bond.	Glycine	154-157	S100 calcium binding protein G	Homo sapiens	28-41
2197361-1	1990	Myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyzes the covalent attachment of myristic acid to the NH2-terminal Gly residues of a number of viral and cellular proteins.	Glycine	122-125	N-myristoyltransferase 1	Homo sapiens	22-44
2197361-1	1990	Myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyzes the covalent attachment of myristic acid to the NH2-terminal Gly residues of a number of viral and cellular proteins.	Glycine	122-125	N-myristoyltransferase 1	Homo sapiens	46-49
2338557-3	1990	In this article, glycine is shown to increase the Ca2(+)-dependent release of [3H]norepinephrine from preloaded slices of the rat hippocampus.	Glycine	17-24	carbonic anhydrase 2	Rattus norvegicus	50-53
2123526-5	1990	In starved rats, TRH-Gly apparently stimulated TSH and PRL secretion in a dose-dependent manner, and the stimulatory activity increased in starved rats as compared to normal controls.	Glycine	21-24	prolactin	Rattus norvegicus	55-58
2158927-7	1990	The extensively studied CYC1 gene encodes iso-1-cytochrome c; the UTR1 and UTR3 genes encode dispensible proteins whose functions are unknown; the OSM1 gene encodes a protein required for growth on hypertonic media; the tRNA(Gly) gene encodes a glycine tRNA; and the RAD7 gene encodes a protein required for repair of UV-induced damage.	Glycine	245-252	fumarate reductase	Saccharomyces cerevisiae S288C	147-151
2325102-0	1990	The clinical features of three babies with osteogenesis imperfecta resulting from the substitution of glycine by arginine in the pro alpha 1(I) chain of type I procollagen.	Glycine	102-109	collagen type I alpha 2 chain	Homo sapiens	153-171
2180962-8	1990	The anchorage-independent phenotype of c-sis-overexpressing cells was blocked by the cell adhesion sequence of fibronectin, Arg-Gly-Asp-Ser.	Glycine	128-131	fibronectin 1	Homo sapiens	111-122
1688557-6	1990	The possibility that the stimulation of flux by adrenergic agonists and vasopressin is mediated by increases in cytoplasmic Ca2+ which in turn could regulate mitochondrial glycine catabolism was examined by measuring flux through GCS in isolated mitochondria in the presence of 0.04-2.88 microM free Ca2+.	Glycine	172-179	arginine vasopressin	Rattus norvegicus	72-83
2354880-5	1990	Feasibility of the approach has been demonstrated by the syntheses of the C-terminal octapeptide from human proinsulin, H-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH, and the serum thymic factor pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH.	Glycine	138-141	insulin	Homo sapiens	108-118
2354880-5	1990	Feasibility of the approach has been demonstrated by the syntheses of the C-terminal octapeptide from human proinsulin, H-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH, and the serum thymic factor pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH.	Glycine	207-210	insulin	Homo sapiens	108-118
2334716-4	1990	Glycine at position 12 (present in all homologues of PTH and in PTHrP), which is predicted in both hormones to participate in a beta-turn, was examined by substituting conformational reporters, such as D- or L-Ala, Pro, and alpha-aminoisobutyric acid (Aib), in both agonist and antagonist analogues.	Glycine	0-7	parathyroid hormone like hormone	Bos taurus	64-69
2405851-3	1990	From the expression plasmid construct the expected product was hPTH with an N-terminal extension of Met-Gly.	Glycine	104-107	parathyroid hormone	Homo sapiens	63-67
2105083-7	1990	A peptide analogous to the calcium binding regions of calmodulin, Asp-Lys-Asp-Gly-Asn-Gly-Thr-Ile-Thr-Thr-Lys-Glu, is also converted, upon heating, to chromatographically different forms in reversed-phase chromatography.	Glycine	78-81	calmodulin 1	Homo sapiens	54-64
1715119-2	1990	This peptide represents residues Glu1737-Ser1750 of the mature von Willebrand factor (vWF) subunit and contains the sequence Arg-Gly-Asp, thought to be important in mediating binding to the platelet receptor glycoprotein (GP) IIb-IIIa complex.	Glycine	129-132	von Willebrand factor	Homo sapiens	86-89
1715119-5	1990	In particular, two antibodies bound to epitopes on vWF that included one or more of the three residues (arginine, glycine, aspartic acid) thought to be involved in binding to GP IIb-IIIa, whereas one antibody bound to an epitope that did not include any of those residues.	Glycine	114-121	von Willebrand factor	Homo sapiens	51-54
1715119-7	1990	In spite of the cross-reactivity for binding to vWF, only the two antibodies whose epitopes included residues in the Arg-Gly-Asp sequence inhibited vWF interaction with GP IIb-IIIa.	Glycine	121-124	von Willebrand factor	Homo sapiens	148-151
2105083-7	1990	A peptide analogous to the calcium binding regions of calmodulin, Asp-Lys-Asp-Gly-Asn-Gly-Thr-Ile-Thr-Thr-Lys-Glu, is also converted, upon heating, to chromatographically different forms in reversed-phase chromatography.	Glycine	86-89	calmodulin 1	Homo sapiens	54-64
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	60-63	rhodopsin	Homo sapiens	34-43
1705626-3	1990	The hormone also stimulated the incorporation of [3H]glycine into extracellular matrix glycoproteins and proteoglycans synthesized by cultures rendered quiescent by maintenance on serum-free medium for 48 h prior to exposure to Ang II.	Glycine	49-60	angiotensinogen	Rattus norvegicus	228-234
2193150-8	1990	The migration-promoting effect of fibronectin can be specifically inhibited both in vivo and in vitro by antibodies to fibronectin, integrin receptors, or by peptides containing the Arg-Gly-Asp-Ser sequence.	Glycine	186-189	fibronectin 1	Homo sapiens	34-45
2193150-9	1990	Neural crest cells recognize two major adhesion sites along fibronectin molecules; these are the Arg-Gly-Asp-Ser sequence located in the medial part of the molecule and the CS1 site situated in the alternatively spliced IIICS region.	Glycine	101-104	fibronectin 1	Homo sapiens	60-71
1967187-4	1990	Characterization of the alpha 1AT Mmineral springs gene demonstrated that it differed from the common normal M1(Ala213) allele by a single-base substitution causing the amino acid substitution Gly-67 (GGG)----Glu-67 (GAG).	Glycine	193-196	serpin family A member 1	Homo sapiens	24-33
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	rhodopsin	Homo sapiens	34-43
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	rhodopsin	Homo sapiens	34-43
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	rhodopsin	Homo sapiens	34-43
33773999-6	2021	At the functional level, we found that GluN1-M641I/GluN2 and GluN1-A645S/GluN2 receptors expressed in HEK293 cells have wild-type EC50 values for both glutamate and glycine; in contrast, GluN1-Y647S/GluN2 receptors do not produce glutamate-induced currents.	Glycine	165-172	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	61-66
33773999-6	2021	At the functional level, we found that GluN1-M641I/GluN2 and GluN1-A645S/GluN2 receptors expressed in HEK293 cells have wild-type EC50 values for both glutamate and glycine; in contrast, GluN1-Y647S/GluN2 receptors do not produce glutamate-induced currents.	Glycine	165-172	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	39-44
2160176-3	1990	Both mild and grave patterns of the AAS are characterized by the rise of the content of alpha-aminobutyric acid, glycine, valine, phenylalanine, ammonia and by a dramatic decline of the glutamine level.	Glycine	113-120	FYVE, RhoGEF and PH domain containing 1	Homo sapiens	36-39
33773999-6	2021	At the functional level, we found that GluN1-M641I/GluN2 and GluN1-A645S/GluN2 receptors expressed in HEK293 cells have wild-type EC50 values for both glutamate and glycine; in contrast, GluN1-Y647S/GluN2 receptors do not produce glutamate-induced currents.	Glycine	165-172	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	61-66
33126251-5	2021	Hence, nutraceuticals that promote GLP-2 secretion from L cells-effective pre/probiotics, glycine, and glutamine-as well as diets rich in soluble fiber or resistant starch, can support intestinal barrier function.	Glycine	90-97	glucagon	Homo sapiens	35-40
26222336-2	2015	The ALS-associated mutations in the glycine-rich C-terminal domain of TDP-43 established a causal link between TDP-43 and disease, and conferred both loss- and gain-of-function properties in neurons.	Glycine	36-43	TAR DNA binding protein	Homo sapiens	70-76
33808167-6	2021	Ca2+ amplitudes upon glycine and acetylcholine applications were increased in SGCE MSNs, but not after GABA or glutamate applications.	Glycine	21-28	sarcoglycan epsilon	Homo sapiens	78-82
33807656-3	2021	All six beta-type connexins expressed in human epidermis (Cx26, Cx30, Cx30.3, Cx31, Cx31.1 and Cx32) contain a glycine at position 12 (G12).	Glycine	111-118	gap junction protein beta 2	Homo sapiens	58-62
33806675-11	2021	In contrast, SLC38A5 is a Na+-coupled transporter with rather restricted specificity towards glutamine, serine, glycine, and methionine.	Glycine	112-119	solute carrier family 38 member 5	Homo sapiens	13-20
33764612-9	2021	We show that PRMT6 also has preference for glycine, but only in the position immediately following the target arginine.	Glycine	43-50	protein arginine methyltransferase 6	Homo sapiens	13-18
33806675-0	2021	SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine-Glycine-One-Carbon Pathways in Cancer.	Glycine	56-63	solute carrier family 38 member 5	Homo sapiens	12-19
33806675-9	2021	SLC6A14 and SLC38A5 are the two transporters that are upregulated in a variety of cancers to mediate the influx of glutamine, serine, glycine, and methionine into cancer cells.	Glycine	134-141	solute carrier family 38 member 5	Homo sapiens	12-19
32917738-3	2020	Here, motivated by work in fission yeast (Schizosaccharomyces pombe), we generated a fluorescent moss (Physcomitrium [Physcomitrella] patens) ROP4 fusion protein by inserting mNeonGreen after Glycine 134.	Glycine	192-199	Rop4	Physcomitrella patens	142-146
26222336-2	2015	The ALS-associated mutations in the glycine-rich C-terminal domain of TDP-43 established a causal link between TDP-43 and disease, and conferred both loss- and gain-of-function properties in neurons.	Glycine	36-43	TAR DNA binding protein	Homo sapiens	111-117
25659913-4	2015	Here, using BSP-SLIM method, a novel binding site within the core of spiral beta-strands-1-5 of LBD-GLUN1 has been predicted in glycine-bound GLUN1 conformation in addition to the glycine pocket in Apo-GLUN1.	Glycine	128-135	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	100-105
25659913-8	2015	All these results suggest that nefiracetam can favorably complete with glycine for GLUN1-LBD in a two-step process, first by binding to a novel site of GLUN1-LBD-NMDA receptor followed by disruption of glycine-binding dynamics then replacing glycine in the GLUN1-LBD cleft.	Glycine	71-78	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	83-88
25659913-4	2015	Here, using BSP-SLIM method, a novel binding site within the core of spiral beta-strands-1-5 of LBD-GLUN1 has been predicted in glycine-bound GLUN1 conformation in addition to the glycine pocket in Apo-GLUN1.	Glycine	128-135	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	142-147
25659913-8	2015	All these results suggest that nefiracetam can favorably complete with glycine for GLUN1-LBD in a two-step process, first by binding to a novel site of GLUN1-LBD-NMDA receptor followed by disruption of glycine-binding dynamics then replacing glycine in the GLUN1-LBD cleft.	Glycine	71-78	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	152-157
25659913-8	2015	All these results suggest that nefiracetam can favorably complete with glycine for GLUN1-LBD in a two-step process, first by binding to a novel site of GLUN1-LBD-NMDA receptor followed by disruption of glycine-binding dynamics then replacing glycine in the GLUN1-LBD cleft.	Glycine	71-78	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	152-157
25659913-4	2015	Here, using BSP-SLIM method, a novel binding site within the core of spiral beta-strands-1-5 of LBD-GLUN1 has been predicted in glycine-bound GLUN1 conformation in addition to the glycine pocket in Apo-GLUN1.	Glycine	128-135	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	142-147
25659913-4	2015	Here, using BSP-SLIM method, a novel binding site within the core of spiral beta-strands-1-5 of LBD-GLUN1 has been predicted in glycine-bound GLUN1 conformation in addition to the glycine pocket in Apo-GLUN1.	Glycine	180-187	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	100-105
25659913-4	2015	Here, using BSP-SLIM method, a novel binding site within the core of spiral beta-strands-1-5 of LBD-GLUN1 has been predicted in glycine-bound GLUN1 conformation in addition to the glycine pocket in Apo-GLUN1.	Glycine	180-187	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	142-147
25659913-4	2015	Here, using BSP-SLIM method, a novel binding site within the core of spiral beta-strands-1-5 of LBD-GLUN1 has been predicted in glycine-bound GLUN1 conformation in addition to the glycine pocket in Apo-GLUN1.	Glycine	180-187	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	142-147
25659913-5	2015	Within the core of spiral beta-strands-1-5 of LBD-GLUN1 pocket, all-atom molecular dynamics simulation revealed that nefiracetam disrupts Arg523-glycine-Asp732 interaction resulting in open GLUN1 conformation and ultimate diffusion of glycine out of the clamshell cleft.	Glycine	145-152	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	50-55
25659913-5	2015	Within the core of spiral beta-strands-1-5 of LBD-GLUN1 pocket, all-atom molecular dynamics simulation revealed that nefiracetam disrupts Arg523-glycine-Asp732 interaction resulting in open GLUN1 conformation and ultimate diffusion of glycine out of the clamshell cleft.	Glycine	235-242	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	50-55
8070361-2	1994	The rat PACE4 sequence has the Asp-His-Ser catalytic site triad, an Arg-Gly-Asp potential integrin binding site, and three potential sites for N-linked glycosylation.	Glycine	72-75	proprotein convertase subtilisin/kexin type 6	Rattus norvegicus	8-13
15496467-4	2004	Our results with mutation of the conserved Ala to Gly in two S lipoxygenases (mouse 8S-LOX and human 15-LOX-2) and the corresponding Gly-Ala substitution in two R lipoxygenases (human 12R-LOX and coral 8R-LOX) reveal that the basis for R or S stereo-control also involves a switch in the position of oxygenation on the substrate.	Glycine	50-53	arachidonate 8-lipoxygenase	Mus musculus	84-90
15496467-4	2004	Our results with mutation of the conserved Ala to Gly in two S lipoxygenases (mouse 8S-LOX and human 15-LOX-2) and the corresponding Gly-Ala substitution in two R lipoxygenases (human 12R-LOX and coral 8R-LOX) reveal that the basis for R or S stereo-control also involves a switch in the position of oxygenation on the substrate.	Glycine	50-53	arachidonate 15-lipoxygenase type B	Homo sapiens	101-109
34716565-0	2022	Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor.	Glycine	102-109	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	11-30
34918931-2	2022	Here, we describe the design and synthesis of a series of (R)-3-(5-furanyl)carboxamido-2-aminopropanoic acid analogues 8a-s as agonists at the glycine (Gly) binding site in the GluN1 subunit, but not GluN3 subunits, of NMDA receptors.	Glycine	143-150	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	177-182
34918931-2	2022	Here, we describe the design and synthesis of a series of (R)-3-(5-furanyl)carboxamido-2-aminopropanoic acid analogues 8a-s as agonists at the glycine (Gly) binding site in the GluN1 subunit, but not GluN3 subunits, of NMDA receptors.	Glycine	152-155	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	177-182
34968493-6	2022	Metabolomic analysis of PFAS-exposed prostaspheres revealed increased glycolytic pathways including the Warburg effect as well as strong enrichment of serine and glycine metabolism which may promote a pre-malignant SPC fate.	Glycine	162-169	surfactant protein C	Homo sapiens	215-218
34736958-2	2022	It is now established that many NMDA receptors in the nervous system are triheteromeric, composed of two glycine-binding GluN1 subunits and two different glutamate binding GluN2 subunits.	Glycine	105-112	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	121-126
34378188-1	2021	BACKGROUND AND PURPOSE: Previous studies showed that glycine receptors (GlyRs) composed of alpha1 and beta subunits are primarily found in spinal cord and brainstem and are potentiated by ethanol (10-100 mM).	Glycine	53-60	brain protein 1	Mus musculus	91-106
34936214-4	2022	Compound 5, a glycine conjugated derivativeof FXR agonist 4, was designed to extend the chemical space of existing FXR agonists.	Glycine	14-21	nuclear receptor subfamily 1, group H, member 4	Mus musculus	46-49
34936214-4	2022	Compound 5, a glycine conjugated derivativeof FXR agonist 4, was designed to extend the chemical space of existing FXR agonists.	Glycine	14-21	nuclear receptor subfamily 1, group H, member 4	Mus musculus	115-118
34881818-8	2022	In contrast, suppression of FXR with Gly-beta-MCA, a bile acid and an intestine-selective and high-affinity FXR inhibitor, abrogated L. Plantarum-mediated protection on the ileum of IR mice.	Glycine	37-40	nuclear receptor subfamily 1, group H, member 4	Mus musculus	28-31
34881818-8	2022	In contrast, suppression of FXR with Gly-beta-MCA, a bile acid and an intestine-selective and high-affinity FXR inhibitor, abrogated L. Plantarum-mediated protection on the ileum of IR mice.	Glycine	37-40	nuclear receptor subfamily 1, group H, member 4	Mus musculus	108-111
34587244-4	2021	Supplementation with GlyNAC (combination of glycine and N-acetylcysteine as a cysteine precursor) was found to improve/correct cellular glycine, cysteine, and GSH deficiencies; lower OxS; and improve mitochondrial function, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, and multiple aging hallmarks; and improve muscle strength, exercise capacity, cognition, and body composition.	Glycine	44-51	insulin	Homo sapiens	238-245
34525858-3	2021	Besides, similar to PBA, D4F inhibited gly-HDL-induced ER stress response activation evaluated through the decreased PERK and eIF2alpha phosphorylation, together with reduced ATF6 nuclear translocation as well as the downregulation of GRP78 and CHOP.	Glycine	39-42	heat shock protein 5	Mus musculus	235-240
34646012-5	2021	Here we show that the cytokine-binding segments of human ALK and LTK comprise a novel architectural chimera of a permuted TNF-like module that braces a glycine-rich subdomain featuring a hexagonal lattice of long polyglycine type II helices.	Glycine	152-159	tumor necrosis factor	Homo sapiens	122-125
34917610-10	2021	Moreover, we found that the increase in (Ca2+)i may be caused by changes in the distribution and expression of inositol 1,4,5-triphosphate receptor (IP3R1) and voltage-dependent anion channel 1 (VDAC1), while Gly can restore the distribution and expression of IP3R1 and VDAC1 to normal levels.	Glycine	209-212	inositol 1,4,5-trisphosphate receptor type 1	Homo sapiens	260-265
34247034-4	2021	Homologous modeling and molecular docking results indicated that the key amino acids of KA/2A9/3 scFv are TYR-92 (CDRL3), SER-93 (CDRL3), ASP-155 (CDRH1) and GLY-226 (CDRH3), and the hydrogen bond is the main force.	Glycine	158-161	immunglobulin heavy chain variable region	Homo sapiens	97-101
34917610-11	2021	Apoptosis-related indexes (Caspase 3 activity and Annexin-V) and gene expression Bax, Cyto C, and Caspase 3) were significantly increased in the TG group, but they could be restored by adding Gly.	Glycine	192-195	caspase 3	Homo sapiens	27-36
34917610-11	2021	Apoptosis-related indexes (Caspase 3 activity and Annexin-V) and gene expression Bax, Cyto C, and Caspase 3) were significantly increased in the TG group, but they could be restored by adding Gly.	Glycine	192-195	BCL2 associated X, apoptosis regulator	Homo sapiens	81-84
34917610-11	2021	Apoptosis-related indexes (Caspase 3 activity and Annexin-V) and gene expression Bax, Cyto C, and Caspase 3) were significantly increased in the TG group, but they could be restored by adding Gly.	Glycine	192-195	caspase 3	Homo sapiens	98-107
34899171-2	2021	Herein, we evaluated the possibility that MeHg could accelerate neuronal death of the motor neuron-like NSC34 cells transiently overexpressing the human Cu2+/Zn2+superoxide dismutase 1 (SOD1) gene mutated at glycine 93 (SOD1-G93A).	Glycine	208-215	superoxide dismutase 1	Homo sapiens	153-184
34899171-2	2021	Herein, we evaluated the possibility that MeHg could accelerate neuronal death of the motor neuron-like NSC34 cells transiently overexpressing the human Cu2+/Zn2+superoxide dismutase 1 (SOD1) gene mutated at glycine 93 (SOD1-G93A).	Glycine	208-215	superoxide dismutase 1	Homo sapiens	186-190
34946802-0	2021	Beyond Sector Retinitis Pigmentosa: Expanding the Phenotype and Natural History of the Rhodopsin Gene Codon 106 Mutation (Gly-to-Arg) in Autosomal Dominant Retinitis Pigmentosa.	Glycine	122-125	rhodopsin	Homo sapiens	87-96
34888425-2	2021	Besides the proposed R- and T-states, previous kinetic results suggested functionally relevant different R-states of the maize enzyme (ZmPEPC-C4) elicited by PEP or its two kinds of activators, glucose 6-phosphate or glycine.	Glycine	217-224	phosphoenolpyruvate carboxylase 2	Zea mays	158-161
34944586-0	2021	Reduction of Rapid Proliferating Tumour Cell Lines by Inhibition of the Specific Glycine Transporter GLYT1.	Glycine	81-88	solute carrier family 6 member 9	Homo sapiens	101-106
34944586-2	2021	The present study analysed the role of the specific glycine transporter GLYT1 in supplying glycine to cancer cells and maintaining cell proliferation.	Glycine	52-59	solute carrier family 6 member 9	Homo sapiens	72-77
34944586-2	2021	The present study analysed the role of the specific glycine transporter GLYT1 in supplying glycine to cancer cells and maintaining cell proliferation.	Glycine	91-98	solute carrier family 6 member 9	Homo sapiens	72-77
34620721-0	2021	Glycine release is potentiated by cAMP via EPAC2 and Ca2+ stores in a retinal interneuron.	Glycine	0-7	Rap guanine nucleotide exchange factor 4	Homo sapiens	43-48
34620721-11	2021	We propose that cAMP elevations in the AII-AC leads to a robust enhancement of glycine release through an EPAC2 and Ca2+ store signaling pathway.	Glycine	79-86	Rap guanine nucleotide exchange factor 4	Homo sapiens	106-111
34620721-15	2021	Therefore, we propose that light-sensitive neuromodulators may change the output of glycine release from AII amacrine cells.	Glycine	84-91	NLR family pyrin domain containing 3	Homo sapiens	105-108
34734802-8	2021	Substitution of this glycine with alanine, a residue conserved in BTLA and several SHP1-recruiting receptors, was sufficient to induce PD-1:SHP1 interaction in T cells.	Glycine	21-28	LOW QUALITY PROTEIN: B- and T-lymphocyte attenuator	Sus scrofa	66-70
34363482-3	2021	METHODS: Using novel glycine-site agonist AICP, local infusion studies and genetic models, we elucidated the role of GluN2C-containing receptors in fear extinction.	Glycine	21-28	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	Mus musculus	117-123
34355840-4	2021	As revealed by the NMR probes of dynamics, including backbone chemical shifts, intra-methyl cross-correlated relaxation rates and glycine-based singlet-states, the C-terminal region of Abeta, especially the G33-L34-M35 segment, plays a particular role in the early steps of temperature-induced Abeta aggregation.	Glycine	130-137	amyloid beta precursor protein	Homo sapiens	185-190
34077620-7	2021	ZG16 crystal structures also draw attention to a non-proline cis peptide bond that can isomerize within the protein and to the mobility of glycine-rich loops in the glycan-binding site.	Glycine	139-146	zymogen granule protein 16	Homo sapiens	0-4
34293440-5	2021	In this report, we generated a tagless RPT by inserting a tobacco etch virus (TEV) protease recognition sequence (ENLYGQ(G/S)) immediately upstream of a native glycine residue at position 312 in Pmel17.	Glycine	160-167	premelanosome protein	Homo sapiens	195-201
34593560-6	2021	In addition, WMS-1410 completely prevented the decrease in insulin secretion of about 32 % provoked by a 24-h-treatment with NMDA/glycine.	Glycine	130-137	insulin	Homo sapiens	59-66
34400347-5	2021	Moreover, mutation of the glycine following the first cysteine in the B-chain of IGF-1 to serine, in concert with substitution to the connecting peptide of LCDV1-VILP, converted native IGF-1 to a high potency antagonist.	Glycine	26-33	insulin like growth factor 1	Homo sapiens	81-86
34400347-5	2021	Moreover, mutation of the glycine following the first cysteine in the B-chain of IGF-1 to serine, in concert with substitution to the connecting peptide of LCDV1-VILP, converted native IGF-1 to a high potency antagonist.	Glycine	26-33	insulin like growth factor 1	Homo sapiens	185-190
34720086-3	2021	Here we show that PHGDH was monoubiquitinated by cullin 4A-based E3 ligase complex at lysine 146 in colorectal cancer (CRC) cells, which enhanced PHGDH activity by recruiting a chaperone protein, DnaJ homolog subfamily A member 1, to promote its tetrameric formation, thereby increasing the levels of serine, glycine, and S-adenosylmethionine (SAM).	Glycine	309-316	cullin 4A	Homo sapiens	49-58
34720086-3	2021	Here we show that PHGDH was monoubiquitinated by cullin 4A-based E3 ligase complex at lysine 146 in colorectal cancer (CRC) cells, which enhanced PHGDH activity by recruiting a chaperone protein, DnaJ homolog subfamily A member 1, to promote its tetrameric formation, thereby increasing the levels of serine, glycine, and S-adenosylmethionine (SAM).	Glycine	309-316	DnaJ heat shock protein family (Hsp40) member A1	Homo sapiens	196-229
34768622-12	2021	Homology models of two deleterious variants in the stalk of DNAH11, p.Gly3102Asp and p.Leu3127Arg, revealed structural importance of the conserved glycine and leucine.	Glycine	147-154	dynein axonemal heavy chain 11	Homo sapiens	60-66
34524407-4	2021	Recently, calpain-2 (CAPN2) was reported to cleave JP2 at a novel site between Glycine 482 (G482) and Threonine 483 (T483).	Glycine	79-86	calpain 2	Homo sapiens	10-19
34986531-4	2021	Recently, accumulating evidences have revealed two types of GluN3-containing NMDAR: glutamate-gated GluN1/GluN2/GluN3 NMDAR and glycine-gated GluN1/GluN3 NMDAR.	Glycine	128-135	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	142-147
34524407-4	2021	Recently, calpain-2 (CAPN2) was reported to cleave JP2 at a novel site between Glycine 482 (G482) and Threonine 483 (T483).	Glycine	79-86	calpain 2	Homo sapiens	21-26
34537246-6	2021	LARKS have high glycine content, which enables kinks to form as exemplified by the known LARKS-rich amyloidogenic structures of TDP43, FUS, and hnRNPA2, three proteins that are known to participate in MLOs.	Glycine	16-23	TAR DNA binding protein	Homo sapiens	128-133
34554757-3	2021	Our structural analysis conducted for a series of prototypic homooligopeptides based on glycine (Gly) with cysteine (Cys) as a substrate bonding group chemisorbed on Au and Ag metal substrates (GlynCys/Au(Ag), n = 1-9) exhibits the formation by these monolayers secondary structure close to beta-sheet conformation with pronounced odd-even structural effect strongly affecting packing density and conformation of molecules in the monolayer, which depend on the length of molecules and the type of metal substrate.	Glycine	88-95	odd-skipped related transcription factor 1	Homo sapiens	331-334
34554757-3	2021	Our structural analysis conducted for a series of prototypic homooligopeptides based on glycine (Gly) with cysteine (Cys) as a substrate bonding group chemisorbed on Au and Ag metal substrates (GlynCys/Au(Ag), n = 1-9) exhibits the formation by these monolayers secondary structure close to beta-sheet conformation with pronounced odd-even structural effect strongly affecting packing density and conformation of molecules in the monolayer, which depend on the length of molecules and the type of metal substrate.	Glycine	97-100	odd-skipped related transcription factor 1	Homo sapiens	331-334
34675940-4	2021	Mechanistically, glycine shapes macrophage polarization via cellular signaling pathways (e.g., NF-kappaB, NRF2, and Akt) and microRNAs.	Glycine	17-24	NFE2 like bZIP transcription factor 2	Homo sapiens	106-110
34675940-4	2021	Mechanistically, glycine shapes macrophage polarization via cellular signaling pathways (e.g., NF-kappaB, NRF2, and Akt) and microRNAs.	Glycine	17-24	AKT serine/threonine kinase 1	Homo sapiens	116-119
34635505-5	2022	Our data show that FLT3-ITD constitutively activates the STAT5 signaling pathway, which upregulates the expression of glycine amidinotransferase (GATM), the first rate-limiting enzyme of de novo creatine biosynthesis.	Glycine	118-125	fms related receptor tyrosine kinase 3	Homo sapiens	19-23
34675920-5	2021	This study involved generating a novel CAR by deletion of two consecutive glycine residues in the CD8 hinge domain of second-generation (2nd) CAR, thereafter named 2nd-GG CAR.	Glycine	74-81	nuclear receptor subfamily 1, group I, member 3	Mus musculus	39-42
34675920-5	2021	This study involved generating a novel CAR by deletion of two consecutive glycine residues in the CD8 hinge domain of second-generation (2nd) CAR, thereafter named 2nd-GG CAR.	Glycine	74-81	nuclear receptor subfamily 1, group I, member 3	Mus musculus	142-145
34675920-5	2021	This study involved generating a novel CAR by deletion of two consecutive glycine residues in the CD8 hinge domain of second-generation (2nd) CAR, thereafter named 2nd-GG CAR.	Glycine	74-81	nuclear receptor subfamily 1, group I, member 3	Mus musculus	171-174
34537246-6	2021	LARKS have high glycine content, which enables kinks to form as exemplified by the known LARKS-rich amyloidogenic structures of TDP43, FUS, and hnRNPA2, three proteins that are known to participate in MLOs.	Glycine	16-23	FUS RNA binding protein	Homo sapiens	135-138
34537246-6	2021	LARKS have high glycine content, which enables kinks to form as exemplified by the known LARKS-rich amyloidogenic structures of TDP43, FUS, and hnRNPA2, three proteins that are known to participate in MLOs.	Glycine	16-23	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	144-151
34418406-0	2021	Glycine/glycine N-methyltransferase/sarcosine axis mediates benzene-induced hematotoxicity.	Glycine	0-7	glycine N-methyltransferase	Homo sapiens	8-35
34418406-6	2021	Notably, the expression of glycine N-methyltransferase (GNMT), an enzyme catalyzing the transformation of glycine to sarcosine, was upregulated both in 1,4-BQ treated AHH-1 cells and benzene-exposed workers.	Glycine	106-113	glycine N-methyltransferase	Homo sapiens	27-54
34418406-6	2021	Notably, the expression of glycine N-methyltransferase (GNMT), an enzyme catalyzing the transformation of glycine to sarcosine, was upregulated both in 1,4-BQ treated AHH-1 cells and benzene-exposed workers.	Glycine	106-113	glycine N-methyltransferase	Homo sapiens	56-60
34418406-7	2021	These results imply that the glycine/GNMT/sarcosine axis was involved in benzene-induced hematotoxicity.	Glycine	29-36	glycine N-methyltransferase	Homo sapiens	37-41
34254739-0	2021	tRNA-derived fragments: tRF-Gly-CCC-046, tRF-Tyr-GTA-010 and tRF-Pro-TGG-001 as novel diagnostic biomarkers for breast cancer.	Glycine	28-31	telomeric repeat binding factor 1	Homo sapiens	24-27
34102285-4	2021	Using a well-established click chemistry approach, we found that EZH2 can be modified by myristoylation at its N-terminal glycine in lung cancer cells.	Glycine	122-129	enhancer of zeste 2 polycomb repressive complex 2 subunit	Homo sapiens	65-69
34466116-7	2021	The first novel mutation was found at (c.1038InsGG) (p.346Gln < Gly) in which the insertion of GG at DNA position 1038 of exon 2 resulting in a substitution of glutamine into glycine at 346th amino acid of BMP15 protein.	Glycine	64-67	bone morphogenetic protein 15	Homo sapiens	206-211
34466116-7	2021	The first novel mutation was found at (c.1038InsGG) (p.346Gln < Gly) in which the insertion of GG at DNA position 1038 of exon 2 resulting in a substitution of glutamine into glycine at 346th amino acid of BMP15 protein.	Glycine	175-182	bone morphogenetic protein 15	Homo sapiens	206-211
34504293-7	2021	We uncover allosteric coupling within NMDA LBD hetero-dimers, where binding of L-glutamate to the GluN2A LBD stalls clamshell motions of the glycine-binding GluN1 LBD.	Glycine	141-148	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	98-104
34504293-7	2021	We uncover allosteric coupling within NMDA LBD hetero-dimers, where binding of L-glutamate to the GluN2A LBD stalls clamshell motions of the glycine-binding GluN1 LBD.	Glycine	141-148	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	157-162
34254739-7	2021	CONCLUSIONS: tRFs: tRF-Gly-CCC-046, tRF-Tyr-GTA-010 and tRF-Pro-TGG-001 are downregulated in breast cancer and early breast cancer and act as new potential biomarkers for the diagnosis and early diagnosis of breast cancer.	Glycine	23-26	telomeric repeat binding factor 1	Homo sapiens	19-22
34254739-5	2021	RESULTS: Our results demonstrated that tRFs: tRF-Gly-CCC-046, tRF-Tyr-GTA-010 and tRF-Pro-TGG-001 were downregulated in both tissues and sera from breast cancer patients as well as early-stage patients compared with those in the healthy donors.	Glycine	49-52	telomeric repeat binding factor 1	Homo sapiens	45-48
34449768-8	2021	In addition, Gly/Arg genotype of IRS1 gene was associated with significantly higher body mass index, fat mass, %body fat, triglycerides, cholesterol, alkaline phosphate, aspartate transaminase, fasting insulin and HOMA-IR levels in OSA and NAFLD subjects.	Glycine	13-16	insulin	Homo sapiens	202-209
34439534-1	2021	In Arabidopsis, the cytosolic redox protein thioredoxin h2 (Trx-h2) is anchored to the cytoplasmic endomembrane through the myristoylated second glycine residue (Gly2).	Glycine	145-152	Metallo-hydrolase/oxidoreductase superfamily protein	Arabidopsis thaliana	162-166
34502133-5	2021	In this study, we found that K8/K18-Akt binding is downregulated by K8/K18 phosphorylation, specifically phosphorylation of K18 ser7/34/53 residues, whereas the binding is upregulated by K8 gly-62-cys mutation.	Glycine	190-193	thymoma viral proto-oncogene 1	Mus musculus	36-39
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	15-22	zyg-11 related cell cycle regulator	Homo sapiens	73-77
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	15-22	cullin 2	Homo sapiens	110-118
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	31-34	zyg-11 related cell cycle regulator	Homo sapiens	73-77
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	31-34	cullin 2	Homo sapiens	110-118
34214466-5	2021	The structures reveal that ZYG11B and ZER1 utilize their armadillo (ARM) repeats forming a deep and narrow cavity to engage mainly the first four residues of Gly/N-degrons.	Glycine	158-161	zyg-11 related cell cycle regulator	Homo sapiens	38-42
34405311-9	2022	RESULTS: Glycine powder significantly increased the expression of proinflammatory genes and showed exploitation of the NF-kappaB pathway, albeit trehalose powder hardly interfered with cell function and did not trigger the NF-kappaB pathway.	Glycine	9-16	nuclear factor kappa B subunit 1	Homo sapiens	119-128
34425818-11	2021	The structure prediction analysis showed that the missense mutation p.G332E would probably lead to a significant conformational change, thereby preventing the expression of the FUCA1 protein indeed; the 3D structural model of the FUCA1 protein reveals that the glycine at position 332 is located near a catalytic nucleophilic residue.	Glycine	261-268	alpha-L-fucosidase 1	Homo sapiens	177-182
34425818-11	2021	The structure prediction analysis showed that the missense mutation p.G332E would probably lead to a significant conformational change, thereby preventing the expression of the FUCA1 protein indeed; the 3D structural model of the FUCA1 protein reveals that the glycine at position 332 is located near a catalytic nucleophilic residue.	Glycine	261-268	alpha-L-fucosidase 1	Homo sapiens	230-235
34413877-4	2021	NMDARs that contained the P532H within the glycine-binding domain of GluN1 with either the GluN2A or GluN2B subunits were evaluated for changes in their pharmacological and biophysical properties, which surprisingly revealed only modest changes in glycine potency but a significant decrease in glutamate potency, an increase in sensitivity to endogenous zinc inhibition, a decrease in response to maximally effective concentrations of agonists, a shortened synaptic-like response time course, a decreased channel open probability, and a reduced receptor cell surface expression.	Glycine	43-50	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	69-74
34413877-4	2021	NMDARs that contained the P532H within the glycine-binding domain of GluN1 with either the GluN2A or GluN2B subunits were evaluated for changes in their pharmacological and biophysical properties, which surprisingly revealed only modest changes in glycine potency but a significant decrease in glutamate potency, an increase in sensitivity to endogenous zinc inhibition, a decrease in response to maximally effective concentrations of agonists, a shortened synaptic-like response time course, a decreased channel open probability, and a reduced receptor cell surface expression.	Glycine	248-255	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	69-74
34321660-4	2021	Here we describe the cryo-electron microscope structures of human GluN1-GluN2A and GluN1-GluN2B NMDA receptors in complex with S-ketamine, glycine and glutamate.	Glycine	139-146	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	66-71
34342855-3	2022	Integrins recognize oligopeptides present on ECM proteins and are involved in three main types of interaction, namely with collagen, laminin, and the oligopeptide RGD (Arg-Gly-Asp) present on vitronectin and fibronectin proteins.	Glycine	172-175	fibronectin 1	Homo sapiens	208-219
34321660-4	2021	Here we describe the cryo-electron microscope structures of human GluN1-GluN2A and GluN1-GluN2B NMDA receptors in complex with S-ketamine, glycine and glutamate.	Glycine	139-146	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	72-78
34321660-4	2021	Here we describe the cryo-electron microscope structures of human GluN1-GluN2A and GluN1-GluN2B NMDA receptors in complex with S-ketamine, glycine and glutamate.	Glycine	139-146	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	83-88
34342168-7	2021	These findings suggest that the hormonal regulation of GLDC contributes not only to the changes in circulating glycine levels seen in metabolic disease, but also affects glutathione production, possibly as a defense against metabolic disease-associated oxidative stress.	Glycine	111-118	glycine decarboxylase	Mus musculus	55-59
34233759-6	2021	RESULTS: Thirteen metabolites were identified as common biomarkers discriminating ob/ob mice and lepb-/- zebrafish larvae from their respective wild type controls: alanine, citrulline, ethanolamine, glutamine, glycine, histidine, isoleucine, leucine, methionine, phenylalanine, putrescine, serine and threonine.	Glycine	210-217	leptin b	Danio rerio	97-101
34436442-7	2021	While the Gly/Ser ratio increased in all Arabidopsis lines between air and low CO2 conditions, low CO2 conditions led to a higher increase in both Gly and Ser contents in gox1 and gox2.2 mutants when compared to wild-type and gox2.1 plants.	Glycine	147-150	Aldolase-type TIM barrel family protein	Arabidopsis thaliana	171-175
34320345-2	2021	In this study, we demonstrate impaired glycine-oxalate metabolism through alanine-glyoxylate aminotransferase (AGXT) in atherosclerosis.	Glycine	39-46	alanine-glyoxylate aminotransferase	Mus musculus	74-109
34320345-2	2021	In this study, we demonstrate impaired glycine-oxalate metabolism through alanine-glyoxylate aminotransferase (AGXT) in atherosclerosis.	Glycine	39-46	alanine-glyoxylate aminotransferase	Mus musculus	111-115
34320345-4	2021	Agxt deletion in apolipoprotein E-deficient (Apoe-/-) mice decreases the glycine/oxalate ratio and increases atherosclerosis with induction of hepatic pro-atherogenic pathways, predominantly cytokine/chemokine signaling and dysregulated redox homeostasis.	Glycine	73-80	alanine-glyoxylate aminotransferase	Mus musculus	0-4
34320345-4	2021	Agxt deletion in apolipoprotein E-deficient (Apoe-/-) mice decreases the glycine/oxalate ratio and increases atherosclerosis with induction of hepatic pro-atherogenic pathways, predominantly cytokine/chemokine signaling and dysregulated redox homeostasis.	Glycine	73-80	apolipoprotein E	Mus musculus	45-49
34320345-8	2021	Conversely, AGXT overexpression in Apoe-/- mice increases the glycine/oxalate ratio and decreases aortic superoxide, CCL5, and atherosclerosis.	Glycine	62-69	alanine-glyoxylate aminotransferase	Mus musculus	12-16
34320345-8	2021	Conversely, AGXT overexpression in Apoe-/- mice increases the glycine/oxalate ratio and decreases aortic superoxide, CCL5, and atherosclerosis.	Glycine	62-69	apolipoprotein E	Mus musculus	35-39
34306033-3	2021	Based on population studies, clusters in COL1A1 and COL1A2 genes associated with the presence of glycine substitutions leading to fatal outcome have been distinguished and named as "lethal regions."	Glycine	97-104	collagen type I alpha 2 chain	Homo sapiens	52-58
34306033-9	2021	Finally, we identified six glycine substitutions located in lethal regions of COL1A1 and COL1A2 genes, of which four are novel.	Glycine	27-34	collagen type I alpha 2 chain	Homo sapiens	89-95
34306033-11	2021	Similarly, 109 glycine substitutions have been identified in eight lethal clusters of COL1A2, of which 51 have been associated with a fatal manifestation.	Glycine	15-22	collagen type I alpha 2 chain	Homo sapiens	86-92
34225773-0	2021	A 5"-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer.	Glycine	23-26	RNA binding motif protein 17	Homo sapiens	84-89
34233182-3	2021	In this study, we show that GluN2A is phosphorylated at Ser-1459 by Ca2+/calmodulin-dependent kinase IIalpha (CaMKIIalpha) in response to glycine stimulation that mimics LTP in primary neurons.	Glycine	138-145	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	28-34
34233182-5	2021	Loss of SNX27 or CaMKIIalpha function blocks the glycine-induced increase in GluN2A-NMDARs on the neuronal membrane.	Glycine	49-56	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	77-83
34225773-12	2021	Moreover, RBM17 level in tiRNA-Gly high-expressing human PTC tissues is upregulated.	Glycine	31-34	RNA binding motif protein 17	Homo sapiens	10-15
34225773-14	2021	Importantly, tiRNA-Gly can induce exon 16 splicing of MAP4K4 mRNA leading to phosphorylation of downstream signaling pathway, which is RBM17 dependent.	Glycine	19-22	mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens	54-60
34168485-2	2021	Here, we describe the second family with COL2A1 mutation, c.611G>C, Gly204Ala, leading to a replacement of glycine in the core triple helical (Gly-X-Y) domain of COL2A1 gene.	Glycine	107-114	collagen type II alpha 1 chain	Homo sapiens	41-47
34168485-2	2021	Here, we describe the second family with COL2A1 mutation, c.611G>C, Gly204Ala, leading to a replacement of glycine in the core triple helical (Gly-X-Y) domain of COL2A1 gene.	Glycine	107-114	collagen type II alpha 1 chain	Homo sapiens	162-168
34258435-1	2021	The aim of the study was to test the interaction between Thr and Gly in low crude protein (CP) diets in 7 to 28 d broilers on production performance and plasma metabolites.	Glycine	65-68	ceruloplasmin	Gallus gallus	91-93
34201404-6	2021	The consequential changes in extracellular glycine concentration can lead to parallel changes in the activity of NR1/NR2B type NMDA receptors of which glycine is a mandatory agonist, and thereby may reduce neurodegenerative events in the retina.	Glycine	43-50	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	113-116
34201404-6	2021	The consequential changes in extracellular glycine concentration can lead to parallel changes in the activity of NR1/NR2B type NMDA receptors of which glycine is a mandatory agonist, and thereby may reduce neurodegenerative events in the retina.	Glycine	151-158	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	113-116
34201404-9	2021	We have hypothesized that glycine transporter 1 inhibitors and P2Y purinoceptor agonists may have therapeutic importance in neurodegenerative-neuroinflammatory disorders of the retina by decreasing NR1/NR2B NMDA receptor activity and production and release of a series of proinflammatory cytokines from microglial cells.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	198-201
34085156-11	2022	In addition, Gly supplementation attenuated infiltration of CD4+, CD8+ T-lymphocytes, CD11b+ and F4/80+ macrophages in the colon.	Glycine	13-16	integrin alpha M	Mus musculus	86-91
34169068-4	2021	The effect of pathogenic TDP-43 mutations within glycine-rich regions (where the majority of ALS-causing TDP-43 mutations occur) on SG dynamics in motor neurons is poorly understood.	Glycine	49-56	TAR DNA binding protein	Homo sapiens	25-31
34169068-4	2021	The effect of pathogenic TDP-43 mutations within glycine-rich regions (where the majority of ALS-causing TDP-43 mutations occur) on SG dynamics in motor neurons is poorly understood.	Glycine	49-56	TAR DNA binding protein	Homo sapiens	105-111
35543349-7	2022	Furthermore, liver metabolomics based on UPLC-QTOF/MS demonstrated that oral administration of GAA had a significant regulatory effect on the composition of liver metabolites in mice exposed to alcohol intake, especially the levels of the biomarkers involved in the metabolic pathways of riboflavin metabolism, glycine, serine and threonine metabolism, pyruvate metabolism, glycolysis/gluconeogenesis, biosynthesis of unsaturated fatty acids, synthesis and degradation of ketone bodies, fructose and mannose metabolism.	Glycine	311-318	glucosidase, alpha, acid	Mus musculus	95-98
34095107-10	2021	Interestingly, PREP disruption inhibited p-ERK and p-p65 and reduced the levels of proinflammatory cytokines in response to endotoxin and proline-glycine-proline, which guided macrophage/neutrophil infiltration in mice fed a HFD for 24 weeks.	Glycine	146-153	mitogen-activated protein kinase 1	Mus musculus	43-46
34084151-3	2021	All are strongly related to insulin resistance and type 2 diabetes (T2DM) in adults (glycine inversely) and are independent of biological and methodological variations in insulin assays.	Glycine	85-92	insulin	Homo sapiens	28-35
34752284-4	2021	The GroEL minichaperone is fused to a glycine-serine rich linker followed by the enterokinase protease recognition sequence.	Glycine	38-45	GroEL	Escherichia coli	4-9
34090290-5	2021	RESULTS: Results: It was established that distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes for Arg16Gly polymorphism in the beta2 -AR gene was 44.2%, 40.0%, 15.8% in the control group vs. 31.3%; 45.7% and 23.0 among BA patients, respectively (chi2 = 6.59; r = 0.037).	Glycine	71-74	ATPase H+ transporting V0 subunit a2	Homo sapiens	131-136
34090290-5	2021	RESULTS: Results: It was established that distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes for Arg16Gly polymorphism in the beta2 -AR gene was 44.2%, 40.0%, 15.8% in the control group vs. 31.3%; 45.7% and 23.0 among BA patients, respectively (chi2 = 6.59; r = 0.037).	Glycine	80-83	ATPase H+ transporting V0 subunit a2	Homo sapiens	131-136
34090290-5	2021	RESULTS: Results: It was established that distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes for Arg16Gly polymorphism in the beta2 -AR gene was 44.2%, 40.0%, 15.8% in the control group vs. 31.3%; 45.7% and 23.0 among BA patients, respectively (chi2 = 6.59; r = 0.037).	Glycine	84-87	ATPase H+ transporting V0 subunit a2	Homo sapiens	131-136
34090290-7	2021	BA risk was 1.74 times higher in the minor allele carriers (Arg/Gly + Gly/Gly genotypes) for Arg16Gly polymorphism in the beta2 -AR gene.	Glycine	64-67	ATPase H+ transporting V0 subunit a2	Homo sapiens	122-127
34090290-7	2021	BA risk was 1.74 times higher in the minor allele carriers (Arg/Gly + Gly/Gly genotypes) for Arg16Gly polymorphism in the beta2 -AR gene.	Glycine	70-73	ATPase H+ transporting V0 subunit a2	Homo sapiens	122-127
34090290-7	2021	BA risk was 1.74 times higher in the minor allele carriers (Arg/Gly + Gly/Gly genotypes) for Arg16Gly polymorphism in the beta2 -AR gene.	Glycine	74-77	ATPase H+ transporting V0 subunit a2	Homo sapiens	122-127
35393769-5	2022	Here, we demonstrate that the combination of oral glycine and metformin with intravenous PMO enhances PMO activity, dystrophin restoration, extends lifespan, and improves body-wide function and phenotypic rescue of dystrophin /utrophin double knock-out (DKO) mice without any overt adverse effects.	Glycine	50-57	dystrophin, muscular dystrophy	Mus musculus	116-126
35393769-5	2022	Here, we demonstrate that the combination of oral glycine and metformin with intravenous PMO enhances PMO activity, dystrophin restoration, extends lifespan, and improves body-wide function and phenotypic rescue of dystrophin /utrophin double knock-out (DKO) mice without any overt adverse effects.	Glycine	50-57	dystrophin, muscular dystrophy	Mus musculus	215-225
35393769-5	2022	Here, we demonstrate that the combination of oral glycine and metformin with intravenous PMO enhances PMO activity, dystrophin restoration, extends lifespan, and improves body-wide function and phenotypic rescue of dystrophin /utrophin double knock-out (DKO) mice without any overt adverse effects.	Glycine	50-57	utrophin	Mus musculus	227-235
35624196-5	2022	We also found that the stimulation of NMDA receptor by glycine treatment for LTP induction stimulated SynGAP1 phosphorylation, Ras-ERK activation, spine enlargement and SynGAP1 delocalization from the spines in striatal neurons, and these effects were prevented by Rho-kinase inhibition.	Glycine	55-62	synaptic Ras GTPase activating protein 1	Homo sapiens	102-109
35624196-5	2022	We also found that the stimulation of NMDA receptor by glycine treatment for LTP induction stimulated SynGAP1 phosphorylation, Ras-ERK activation, spine enlargement and SynGAP1 delocalization from the spines in striatal neurons, and these effects were prevented by Rho-kinase inhibition.	Glycine	55-62	mitogen-activated protein kinase 1	Homo sapiens	131-134
35624196-5	2022	We also found that the stimulation of NMDA receptor by glycine treatment for LTP induction stimulated SynGAP1 phosphorylation, Ras-ERK activation, spine enlargement and SynGAP1 delocalization from the spines in striatal neurons, and these effects were prevented by Rho-kinase inhibition.	Glycine	55-62	synaptic Ras GTPase activating protein 1	Homo sapiens	169-176
35597955-11	2022	The variants with the largest posterior inclusion probability in the two credible sets were an amino acid change in HLA-DQB1 (glutamine to histidine at residue 253) and a multi-allelic amino acid change in HLA-DRB1 (presence/absence of serine, glycine or leucine at residue 11).	Glycine	244-251	major histocompatibility complex, class II, DR beta 1	Homo sapiens	206-214
35545256-3	2022	At pharmacologically active doses of {greater than or equal to}0.1 mg/kg, both mouse Fc-mouse IL-10 and human Fc-human IL-10, constructed as the C-terminus of the Fc domain fused with IL-10 via a glycine-serine polypeptide linker, exhibited nonlinear pharmacokinetics after intravenous administration to mice at the doses of 0.05, 0.5, and 5 mg/kg.	Glycine	196-203	interleukin 10	Mus musculus	94-99
35579101-5	2022	After instillation, the presence of integrin-beta1 endows coated nanoparticles with steady adhesion via specific binding to Arg-Gly-Asp sequence on the fibronectin of ocular epithelium, achieving durable retention on ocular surface.	Glycine	128-131	fibronectin 1	Homo sapiens	152-163
35548669-0	2022	Nociception in the Glycine Receptor Deficient Mutant Mouse Spastic.	Glycine	19-26	glycine receptor, beta subunit	Mus musculus	59-66
35085745-3	2022	AIM OF THE STUDY: This study aims to evaluate the protective effect and mechanism of GLY on a pathway involving enteric-origin lipopolysaccharide (LPS), toll-like receptor (TLR)4 and NF-kappaB in mice with dextran sulfate sodium (DSS)-induced UC.	Glycine	85-88	toll-like receptor 4	Mus musculus	153-178
35085745-3	2022	AIM OF THE STUDY: This study aims to evaluate the protective effect and mechanism of GLY on a pathway involving enteric-origin lipopolysaccharide (LPS), toll-like receptor (TLR)4 and NF-kappaB in mice with dextran sulfate sodium (DSS)-induced UC.	Glycine	85-88	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	183-192
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	occludin	Mus musculus	111-119
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	tight junction protein 1	Mus musculus	135-139
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	toll-like receptor 4	Mus musculus	211-215
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	224-233
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	interleukin 6	Mus musculus	235-239
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	tumor necrosis factor	Mus musculus	255-264
35085745-11	2022	CONCLUSION: GLY might exert an anti-UC effect by improving the colonic mucosal barrier and inhibiting the enteric-origin LPS/TLR4/NF-kappaB inflammatory pathway, and restoring the homeostasis of the intestinal flora in UC mice.	Glycine	12-15	toll-like receptor 4	Mus musculus	125-129
35085745-11	2022	CONCLUSION: GLY might exert an anti-UC effect by improving the colonic mucosal barrier and inhibiting the enteric-origin LPS/TLR4/NF-kappaB inflammatory pathway, and restoring the homeostasis of the intestinal flora in UC mice.	Glycine	12-15	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	130-139
35533195-5	2022	Here, we generated recombinant EBOVs encoding glycine (G) or arginine (R) mutations at VP35/K309 (rEBOV-VP35/K309G/-R) and show that both mutations prohibit VP35/K309 ubiquitination.	Glycine	46-53	polymerase complex protein	Reston ebolavirus	87-91
35533195-5	2022	Here, we generated recombinant EBOVs encoding glycine (G) or arginine (R) mutations at VP35/K309 (rEBOV-VP35/K309G/-R) and show that both mutations prohibit VP35/K309 ubiquitination.	Glycine	46-53	polymerase complex protein	Reston ebolavirus	104-108
35533195-5	2022	Here, we generated recombinant EBOVs encoding glycine (G) or arginine (R) mutations at VP35/K309 (rEBOV-VP35/K309G/-R) and show that both mutations prohibit VP35/K309 ubiquitination.	Glycine	46-53	polymerase complex protein	Reston ebolavirus	157-161
35139220-3	2022	Arabidopsis (Arabidopsis thaliana) mutants lacking ER-ANT1 (er-ant1 plants) exhibit a photorespiratory phenotype accompanied by high glycine levels and stunted growth, pointing to an inhibition of glycine decarboxylase.	Glycine	133-140	aromatic and neutral transporter 1	Arabidopsis thaliana	54-58
35139220-3	2022	Arabidopsis (Arabidopsis thaliana) mutants lacking ER-ANT1 (er-ant1 plants) exhibit a photorespiratory phenotype accompanied by high glycine levels and stunted growth, pointing to an inhibition of glycine decarboxylase.	Glycine	197-204	aromatic and neutral transporter 1	Arabidopsis thaliana	54-58
35602938-0	2022	Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model.	Glycine	10-17	NPR2 like, GATOR1 complex subunit	Mus musculus	77-82
35602938-6	2022	Proteomic and metabolomics studies of Nprl2 mutants revealed alterations in known epilepsy-implicated proteins and metabolic pathways, including increases in the neurotransmitter, glycine.	Glycine	180-187	NPR2 like, GATOR1 complex subunit	Mus musculus	38-43
35460232-11	2022	Significant genetic and phenotypic correlations were found for glycine and serine-glycine ratio with metabolic disease risk factors including adiposity, insulin sensitivity and inflammation-related phenotypes (rhog = -0.37 to 0.35, P < 0.03, rhop = -0.19 to 0.13, P < 0.006).	Glycine	63-70	insulin	Homo sapiens	153-160
35456407-11	2022	In short, we find differential expression profiles and predict that tiRNA-1:33-Gly-GCC-1, tRF-1:32-Gly-GCC-1, and tRF-+1:T20-Ser-TGA-1 are very likely to engage in the pathophysiological process of MIBC via regulating the target genes in the key pathways.	Glycine	99-102	telomeric repeat binding factor 1	Homo sapiens	90-95
35531129-5	2022	Experimental approach: In this study, the Fc domain of human IgG1 with serine-glycine linkers was attached to the C-terminal of a GH superagonist via molecular cloning.	Glycine	78-85	growth hormone 1	Homo sapiens	130-132
35383225-6	2022	It was found that glycine was not polymerized in the experimental condition assayed, but partially decomposed to ethanol under pressures of 1 and 6 GPa and shear strains of < 120 m/m.	Glycine	18-25	glycophorin A (MNS blood group)	Homo sapiens	148-151
35384358-1	2022	HLA-A*24:516 has one nucleotide change from HLA-A*24:02:01:01 at nucleotide 194 where Alanine (41) is changed to Glycine.	Glycine	113-120	major histocompatibility complex, class I, A	Homo sapiens	0-5
35384358-1	2022	HLA-A*24:516 has one nucleotide change from HLA-A*24:02:01:01 at nucleotide 194 where Alanine (41) is changed to Glycine.	Glycine	113-120	major histocompatibility complex, class I, A	Homo sapiens	44-49
35217385-1	2022	N-methyl-D-aspartate receptors (NMDAR) are di- or tri-heterotetrameric ligand-gated ion channels composed of two obligate glycine-binding GluN1 subunits and two glutamate-binding GluN2 or GluN3 subunits, encoded by GRIN1, GRIN2A-D, and GRIN3A-B receptor genes respectively.	Glycine	122-129	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	138-143
35217385-1	2022	N-methyl-D-aspartate receptors (NMDAR) are di- or tri-heterotetrameric ligand-gated ion channels composed of two obligate glycine-binding GluN1 subunits and two glutamate-binding GluN2 or GluN3 subunits, encoded by GRIN1, GRIN2A-D, and GRIN3A-B receptor genes respectively.	Glycine	122-129	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	215-220
35144620-1	2022	RATIONALE: The long-acting beta2-agonist/long-acting muscarinic antagonist combination indacaterol/glycopyrronium (IND/GLY) elicits bronchodilation, improves symptoms, and reduces exacerbations in COPD.	Glycine	119-122	ATPase H+ transporting V0 subunit a2	Homo sapiens	27-32
35177655-4	2022	Heterozygous pathogenic COL4A3 and COL4A4 variants affecting Gly (n = 304) in autosomal dominant Alport syndrome were correlated with the risk of haematuria in the UK 100,000 Genomes Project.	Glycine	61-64	collagen type IV alpha 4 chain	Homo sapiens	35-41
35177655-8	2022	Heterozygous pathogenic COL4A3 and COL4A4 variants that resulted in a Gly substitution with a highly destabilising residue (Arg, Val, Glu, Asp, Trp) were associated with an increased risk of haematuria (p = 0.018), and those adjacent to a non-collagenous region were associated with a reduced risk (p = 0.046).	Glycine	70-73	collagen type IV alpha 4 chain	Homo sapiens	35-41
34624079-6	2022	Mechanistically, SHMT2 inhibition led to a significant reduction of intracellular glycine and formate levels, which inhibited the mTOR pathway and thereby triggered autophagic degradation of the oncogenic transcription factor TCF3.	Glycine	82-89	mechanistic target of rapamycin kinase	Homo sapiens	130-134
35052658-0	2022	GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study.	Glycine	8-15	insulin	Homo sapiens	112-119
35052477-6	2022	In the COL2A1 gene, 28 novel variants were identified, and a total of 63% of the variants were found in the triple helix region resulted in glycine substitution in Gly-XY repeats, which were identified in patients with clinical manifestations of congenital spondyloepiphyseal dysplasia with varying severity, and were not found in Stickler syndrome, type I and Kniest dysplasia.	Glycine	140-147	collagen type II alpha 1 chain	Homo sapiens	7-13
2677400-5	1989	Our results indicate that a glutamic acid to glycine change at gp120 amino acid 516, a lysine to isoleucine change at amino acid 517, and an arginine to lysine change at amino acid 518 affect neither gp160 cleavage nor syncytium formation.	Glycine	45-52	glutamyl aminopeptidase	Homo sapiens	200-205
35052477-6	2022	In the COL2A1 gene, 28 novel variants were identified, and a total of 63% of the variants were found in the triple helix region resulted in glycine substitution in Gly-XY repeats, which were identified in patients with clinical manifestations of congenital spondyloepiphyseal dysplasia with varying severity, and were not found in Stickler syndrome, type I and Kniest dysplasia.	Glycine	164-167	collagen type II alpha 1 chain	Homo sapiens	7-13
35491929-3	2022	Here, we show that the LCD of hnRNPA2 interacts with RNA via an embedded Tyr/Gly-rich region which is a disordered RNA-binding motif.	Glycine	77-80	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	30-37
2556391-2	1989	Variant forms of mammalian gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) are present in chicken ([Gln8] GnRH and [His5, Trp7, Tyr8]GnRH), salmon ([Trp7, Leu8]GnRH), and lamprey ([Tyr3, Leu5, Glu6, Trp7, Lys8] GnRH).	Glycine	87-90	gonadotropin releasing hormone 1	Homo sapiens	27-57
2556391-2	1989	Variant forms of mammalian gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) are present in chicken ([Gln8] GnRH and [His5, Trp7, Tyr8]GnRH), salmon ([Trp7, Leu8]GnRH), and lamprey ([Tyr3, Leu5, Glu6, Trp7, Lys8] GnRH).	Glycine	87-90	gonadotropin releasing hormone 1	Homo sapiens	59-63
2556391-2	1989	Variant forms of mammalian gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) are present in chicken ([Gln8] GnRH and [His5, Trp7, Tyr8]GnRH), salmon ([Trp7, Leu8]GnRH), and lamprey ([Tyr3, Leu5, Glu6, Trp7, Lys8] GnRH).	Glycine	103-106	gonadotropin releasing hormone 1	Homo sapiens	27-57
2556391-2	1989	Variant forms of mammalian gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) are present in chicken ([Gln8] GnRH and [His5, Trp7, Tyr8]GnRH), salmon ([Trp7, Leu8]GnRH), and lamprey ([Tyr3, Leu5, Glu6, Trp7, Lys8] GnRH).	Glycine	103-106	gonadotropin releasing hormone 1	Homo sapiens	59-63
2480354-10	1989	A synthetic Arg-Gly-Asp-Ser tetrapeptide (RGDS), specific for fibronectin and vitronectin adhesion receptors, inhibited TRH-, EGF-, and TPA-induced GH4 cell stretching and attachment to fibronectin- and vitronectin-coated dishes.	Glycine	16-19	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	42-46
2480354-10	1989	A synthetic Arg-Gly-Asp-Ser tetrapeptide (RGDS), specific for fibronectin and vitronectin adhesion receptors, inhibited TRH-, EGF-, and TPA-induced GH4 cell stretching and attachment to fibronectin- and vitronectin-coated dishes.	Glycine	16-19	thyrotropin releasing hormone	Rattus norvegicus	120-123
2690069-5	1989	The sequences of the genes for amylin and the calcitonin gene-related peptides (CGRPs) show strong similarity, especially over their 5" coding regions, where both peptides have a conserved intramolecular disulfide bridge, and also over their 3" coding regions, where the presence of a glycine codon strongly suggests that the carboxyl-terminal residue of amylin, like that of CGRP, is amidated.	Glycine	285-292	islet amyloid polypeptide	Homo sapiens	31-37
2480792-7	1989	Glutamine, phosphoribosyl pyrophosphate (PRPP), ATP and glycine were required for the two-step sequence of glutamine:amidophosphoribosyltransferase (EC 2.4.2.14) and phosphoribosylamine-glycine ligase (EC 6.3.4.13).	Glycine	56-63	phosphoribosyl pyrophosphate amidotransferase	Homo sapiens	117-147
2674119-7	1989	Site specific mutations within these 5 residues demonstrate that Gly-508 and Arg-509 are independently involved in calmodulin-dependent binding and activation of myosin light chain kinase.	Glycine	65-68	myosin, heavy chain 15	Gallus gallus	162-168
2808373-4	1989	Because osteopontin mediates cell adhesion and spreading, and contains an Arg-Gly-Asp-Ser cell-binding sequence, our observations strongly suggest that the cell surface localization of pp69 osteopontin is receptor-mediated, and the modification by phosphorylation may be crucial for its receptor binding activity.	Glycine	78-81	secreted phosphoprotein 1	Rattus norvegicus	190-201
2549026-3	1989	In the current study we demonstrate that this apparent Ca2+ channel function is specifically inhibited by the synthetic analogue of the fibrinogen gamma COOH-terminal peptide, His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val (His-12-Val), but not by the adhesive protein sequence Arg-Gly-Asp-Ser (RGDS).	Glycine	188-191	ral guanine nucleotide dissociation stimulator	Homo sapiens	296-300
2529542-6	1989	Furthermore, the murine Fc epsilon RII is truncated at the carboxyl terminus and the Arg-Gly-Asp sequence, a common recognition site of integrin receptors, which is found in the reverse configuration in human Fc epsilon RII, is missing.	Glycine	89-92	Fc receptor, IgE, low affinity II, alpha polypeptide	Mus musculus	24-38
2549026-3	1989	In the current study we demonstrate that this apparent Ca2+ channel function is specifically inhibited by the synthetic analogue of the fibrinogen gamma COOH-terminal peptide, His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val (His-12-Val), but not by the adhesive protein sequence Arg-Gly-Asp-Ser (RGDS).	Glycine	192-195	ral guanine nucleotide dissociation stimulator	Homo sapiens	296-300
2549026-3	1989	In the current study we demonstrate that this apparent Ca2+ channel function is specifically inhibited by the synthetic analogue of the fibrinogen gamma COOH-terminal peptide, His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val (His-12-Val), but not by the adhesive protein sequence Arg-Gly-Asp-Ser (RGDS).	Glycine	192-195	ral guanine nucleotide dissociation stimulator	Homo sapiens	296-300
2549026-3	1989	In the current study we demonstrate that this apparent Ca2+ channel function is specifically inhibited by the synthetic analogue of the fibrinogen gamma COOH-terminal peptide, His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val (His-12-Val), but not by the adhesive protein sequence Arg-Gly-Asp-Ser (RGDS).	Glycine	192-195	ral guanine nucleotide dissociation stimulator	Homo sapiens	296-300
2508560-1	1989	The tertiary structure model of EF-Tu predicts that the amino acid sequence Val-Asp-His-Gly-Lys-Thr-Thr-Leu (residues 20-27) forms a pocket that binds the pyrophosphate group.	Glycine	88-91	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	32-37
2508560-7	1989	In contrast, the Gly-20 form was nearly as active as wild-type EF-Tu in vitro and in vivo.	Glycine	17-20	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	63-68
2529542-6	1989	Furthermore, the murine Fc epsilon RII is truncated at the carboxyl terminus and the Arg-Gly-Asp sequence, a common recognition site of integrin receptors, which is found in the reverse configuration in human Fc epsilon RII, is missing.	Glycine	89-92	Fc epsilon receptor II	Homo sapiens	209-223
2508560-8	1989	This mutation is theoretically equivalent to reversion of the Gly to Val transforming mutation of the cellular form of the ras gene product p21, a protein proposed to be structurally similar to EF-Tu in the GDP binding domain.	Glycine	62-65	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	194-199
2502375-0	1989	Thyrotropin-releasing hormone (TRH)-Gly conversion to TRH in rat ventral prostate is inhibited by castration and aging.	Glycine	36-39	thyrotropin releasing hormone	Rattus norvegicus	0-29
2503371-1	1989	Rat TRH prohormone (pro-TRH) contains five separate copies of the TRH progenitor sequence, Gln-His-Pro-Gly.	Glycine	103-106	thyrotropin releasing hormone	Rattus norvegicus	20-27
2502375-0	1989	Thyrotropin-releasing hormone (TRH)-Gly conversion to TRH in rat ventral prostate is inhibited by castration and aging.	Glycine	36-39	thyrotropin releasing hormone	Rattus norvegicus	31-34
2502375-0	1989	Thyrotropin-releasing hormone (TRH)-Gly conversion to TRH in rat ventral prostate is inhibited by castration and aging.	Glycine	36-39	thyrotropin releasing hormone	Rattus norvegicus	54-57
2750535-6	1989	A glycine-extended gastrin [(5-17)G17-Gly)] elicited a small but significant increase in intracellular free Ca2+ although only at 10(-6) M. This increase was approximately 20% of that obtained with a similar concentration of G17.	Glycine	2-9	gastrin	Sus scrofa	19-26
2597139-4	1989	In stirred platelets, total and specific inhibition of PMA-induced aggregation by a fibrinogen-derived peptide (RGDS, i.e. Arg-Gly-Asp-Ser) promoted maximal increases in membrane-associated PKC in the presence of PMA and completely prevented the loss in cellular activity.	Glycine	127-130	ral guanine nucleotide dissociation stimulator	Homo sapiens	112-116
2613766-10	1989	Migration over intact FGN was almost totally blocked by 230 microM-Arg-Gly-Asp-Ser (RGDS), a peptide known to interact with integrin-type receptors.	Glycine	71-74	ral guanine nucleotide dissociation stimulator	Homo sapiens	84-88
2502375-8	1989	Because testosterone levels do not change during the first 18 months of life in most rat strains, and hypothyroidism in young animals is associated with a significant increase in prostate TRH and TRH-Gly levels, we conclude that the aging-related decline in prostate TRH biosynthesis is not the result of a hypogonadal state.	Glycine	200-203	thyrotropin releasing hormone	Rattus norvegicus	196-199
2681686-1	1989	Endopeptidase (EP) 24.15 cleaves the Tyr5-Gly6 bond of luteinizing hormone-releasing hormone (LHRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), and is the primary LHRH degrading enzyme in pituitary and hypothalamic membrane preparations.	Glycine	42-45	gonadotropin releasing hormone 1	Homo sapiens	55-92
2681686-1	1989	Endopeptidase (EP) 24.15 cleaves the Tyr5-Gly6 bond of luteinizing hormone-releasing hormone (LHRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), and is the primary LHRH degrading enzyme in pituitary and hypothalamic membrane preparations.	Glycine	42-45	gonadotropin releasing hormone 1	Homo sapiens	94-98
2540202-4	1989	The sequence specificity of the Ub-Xase was demonstrated by mutagenesis of the carboxyl-terminal glycine of ubiquitin to an alanine, which inhibited ubiquitin removal in vivo.	Glycine	97-104	ubiquitin	Saccharomyces cerevisiae S288C	108-117
2540202-4	1989	The sequence specificity of the Ub-Xase was demonstrated by mutagenesis of the carboxyl-terminal glycine of ubiquitin to an alanine, which inhibited ubiquitin removal in vivo.	Glycine	97-104	ubiquitin	Saccharomyces cerevisiae S288C	149-158
2502375-8	1989	Because testosterone levels do not change during the first 18 months of life in most rat strains, and hypothyroidism in young animals is associated with a significant increase in prostate TRH and TRH-Gly levels, we conclude that the aging-related decline in prostate TRH biosynthesis is not the result of a hypogonadal state.	Glycine	200-203	thyrotropin releasing hormone	Rattus norvegicus	196-199
2500333-2	1989	Within secretory granules, TRH-Gly is converted to TRH through alpha-amidation of the C-terminal proline residue, using Gly as the NH2 donor.	Glycine	31-34	thyrotropin releasing hormone	Rattus norvegicus	27-30
2708912-8	1989	It is shown in addition that the tripeptide Arg-Gly-Asp, identical to the region of iC3b recognized by CR3 and by several adhesion-promoting receptors that are structurally similar to CR3, such as fibronectin or vitronectin, is a significant inhibitor of the binding to and the phagocytosis of S-RBC by monocytic-macrophagic cells.	Glycine	48-51	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	103-106
2708912-8	1989	It is shown in addition that the tripeptide Arg-Gly-Asp, identical to the region of iC3b recognized by CR3 and by several adhesion-promoting receptors that are structurally similar to CR3, such as fibronectin or vitronectin, is a significant inhibitor of the binding to and the phagocytosis of S-RBC by monocytic-macrophagic cells.	Glycine	48-51	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	184-187
2500352-0	1989	Radioimmunoassay for thyrotropin-releasing hormone precursor peptide, Lys-Arg-Gln-His-Pro-Gly-Arg-Arg.	Glycine	90-93	thyrotropin releasing hormone	Rattus norvegicus	21-50
2500352-1	1989	A radioimmunoassay for thyrotropin-releasing hormone (TRH) precursor peptide Lys-Arg-Gln-His-Pro-Gly-Arg-Arg (pro-TRH), has been developed.	Glycine	97-100	thyrotropin releasing hormone	Rattus norvegicus	23-52
2554575-6	1989	Tick-borne and mosquito-borne flaviviruses share a common hydrophilicity profile and also other features of their primary sequences, such as the presumably functional Gly-Asp-Asp sequence element within protein NS5.	Glycine	167-170	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	211-214
2500352-1	1989	A radioimmunoassay for thyrotropin-releasing hormone (TRH) precursor peptide Lys-Arg-Gln-His-Pro-Gly-Arg-Arg (pro-TRH), has been developed.	Glycine	97-100	thyrotropin releasing hormone	Rattus norvegicus	110-117
2500333-2	1989	Within secretory granules, TRH-Gly is converted to TRH through alpha-amidation of the C-terminal proline residue, using Gly as the NH2 donor.	Glycine	31-34	thyrotropin releasing hormone	Homo sapiens	51-54
2500352-2	1989	Anti-pro-TRH antibody was raised in rabbits immunized with a conjugate of synthetic pro-TRH analog, Cys-Lys-Arg-Gln-His-Pro-Gly-Arg-Arg-Cys (pCC10) to bovine serum albumin.	Glycine	124-127	thyrotropin releasing hormone	Rattus norvegicus	5-12
2500352-2	1989	Anti-pro-TRH antibody was raised in rabbits immunized with a conjugate of synthetic pro-TRH analog, Cys-Lys-Arg-Gln-His-Pro-Gly-Arg-Arg-Cys (pCC10) to bovine serum albumin.	Glycine	124-127	thyrotropin releasing hormone	Rattus norvegicus	84-91
2500333-3	1989	Using specific RIA, we measured the TRH-Gly immunoreactivity (TRH-Gly-IR) and TRH-IR concentrations in tissues from the reproductive and gastrointestinal systems, adrenals, and other internal organs in euthyroid, hypothyroid, and T4-treated 250-g Sprague-Dawley male rats.	Glycine	40-43	thyrotropin releasing hormone	Rattus norvegicus	36-39
2551731-2	1989	DNA sequence analysis of mutant W7 revealed a single base transition in the cytochrome b gene; the mutated residue Gly 131 is perfectly conserved in all known cytochromes b and belongs to the Qo domain.	Glycine	115-118	cytochrome b	Saccharomyces cerevisiae S288C	76-88
2500333-3	1989	Using specific RIA, we measured the TRH-Gly immunoreactivity (TRH-Gly-IR) and TRH-IR concentrations in tissues from the reproductive and gastrointestinal systems, adrenals, and other internal organs in euthyroid, hypothyroid, and T4-treated 250-g Sprague-Dawley male rats.	Glycine	66-69	thyrotropin releasing hormone	Rattus norvegicus	62-65
2500333-3	1989	Using specific RIA, we measured the TRH-Gly immunoreactivity (TRH-Gly-IR) and TRH-IR concentrations in tissues from the reproductive and gastrointestinal systems, adrenals, and other internal organs in euthyroid, hypothyroid, and T4-treated 250-g Sprague-Dawley male rats.	Glycine	66-69	thyrotropin releasing hormone	Rattus norvegicus	62-65
2656396-2	1989	A similar construct was made using a mutant gene encoding a BRP-Bla protein in which the cysteine residue at the +1 position was changed into a glycine residue.	Glycine	144-151	beta-lactamase	Escherichia coli	64-67
2500333-4	1989	TRH-Gly-IR concentrations were more than 2-fold higher than TRH-IR concentrations within the adrenal, pancreas, bowel, and stomach at the time of death.	Glycine	4-7	thyrotropin releasing hormone	Rattus norvegicus	0-3
2527238-2	1989	Since both ligands bind to it through their respective RGDS (Arg-Gly-Asp-Ser) domains and since both have been cloned, we were able to deduce the amino acid sequence of the binding site from the nucleotide sequence coding for RGDS in both proteins.	Glycine	65-68	ral guanine nucleotide dissociation stimulator	Homo sapiens	55-59
2500333-5	1989	Untreated hypothyroidism and exogenous TRH significantly increased adrenal TRH-Gly-IR levels.	Glycine	79-82	thyrotropin releasing hormone	Rattus norvegicus	39-42
2527238-2	1989	Since both ligands bind to it through their respective RGDS (Arg-Gly-Asp-Ser) domains and since both have been cloned, we were able to deduce the amino acid sequence of the binding site from the nucleotide sequence coding for RGDS in both proteins.	Glycine	65-68	ral guanine nucleotide dissociation stimulator	Homo sapiens	226-230
2500333-5	1989	Untreated hypothyroidism and exogenous TRH significantly increased adrenal TRH-Gly-IR levels.	Glycine	79-82	thyrotropin releasing hormone	Rattus norvegicus	75-78
2500333-6	1989	Pancreatic TRH-Gly levels increased about 2-fold in hypothyroid rats.	Glycine	15-18	thyrotropin releasing hormone	Rattus norvegicus	11-14
2500333-7	1989	Incubation at 60 C significantly increased TRH-Gly-IR levels in the pancreas, adrenal, bowel, stomach, and epididymis by 14-, 3-, 6-, 6-, and 6-fold, respectively.	Glycine	47-50	thyrotropin releasing hormone	Rattus norvegicus	43-46
2659586-8	1989	N-terminal sequence analysis of the produced myoglobin revealed a glycine residue at the terminus, indicating that as in native muscle the N-terminal Met was removed in yeast by processing.	Glycine	66-73	myoglobin	Bos taurus	45-54
2546924-3	1989	The Gly at position 55 in the Fic protein was changed to Arg in the Fic-1 protein.	Glycine	4-7	Fic	Escherichia coli	30-33
2500333-8	1989	Also after 60 C incubation increases in the TRH-Gly-IR/TRH-IR ratio of 2.7-, 4-, and 1.7-fold were observed in the pancreas, epididymis, and bowel, respectively.	Glycine	48-51	thyrotropin releasing hormone	Rattus norvegicus	44-47
2500333-9	1989	Pooled tissue extracts were fractionated by cation exchange and reverse phase HPLC for characterization of TRH-Gly-IR.	Glycine	111-114	thyrotropin releasing hormone	Rattus norvegicus	107-110
2646637-4	1989	These assignments provide the basis for interpreting NMR data which demonstrate that the solution structure of hTGF alpha includes an antiparallel beta-sheet involving residues Gly-19 to Leu-24 and Lys-29 to Cys-34 and a second, smaller, antiparallel beta-sheet involving residues Tyr-38 and Val-39 and His-45 and Ala-46.	Glycine	177-180	transforming growth factor alpha	Homo sapiens	111-121
2500333-10	1989	Both chromatographic methods revealed a major peak of TRH-Gly-IR coeluting with synthetic TRH-Gly.	Glycine	58-61	thyrotropin releasing hormone	Rattus norvegicus	54-57
2500333-11	1989	Incubation at 60 C caused 13.5-, 4.1-, 1.5-, and 5-fold increments in the TRH-Gly-IR for adrenal, pancreas, prostate, and thyroid, respectively, compared to the immediately extracted control aliquots.	Glycine	78-81	thyrotropin releasing hormone	Rattus norvegicus	74-77
2500333-12	1989	Cation exchange and reverse phase HPLC also revealed production of higher mol wt TRH precursor peptides after incubation at 60 C for 4 or 20 h. Only the TRH-Gly-IR peak coeluting with pGlu-His-Pro-Gly was converted into TRH by rat brain alpha-amidating enzyme.	Glycine	157-160	thyrotropin releasing hormone	Rattus norvegicus	153-156
2546924-3	1989	The Gly at position 55 in the Fic protein was changed to Arg in the Fic-1 protein.	Glycine	4-7	Fic	Escherichia coli	68-71
2500333-12	1989	Cation exchange and reverse phase HPLC also revealed production of higher mol wt TRH precursor peptides after incubation at 60 C for 4 or 20 h. Only the TRH-Gly-IR peak coeluting with pGlu-His-Pro-Gly was converted into TRH by rat brain alpha-amidating enzyme.	Glycine	157-160	thyrotropin releasing hormone	Rattus norvegicus	153-156
2540822-1	1989	By directed mutagenesis of the cloned Escherichia coli gor gene encoding the flavoprotein glutathione reductase, Tyr-177 (the residue corresponding to Tyr-197 in the NADPH-binding pocket of the homologous human enzyme) was changed to phenylalanine (Y177F), serine (Y177S), and glycine (Y177G).	Glycine	277-284	glutathione-disulfide reductase	Homo sapiens	90-111
2544879-4	1989	The sequence was identical to that previously reported for bovine brain endozepine, except that it lacks the last two residues, -Gly-Ile, at the C terminus.	Glycine	129-132	diazepam binding inhibitor, acyl-CoA binding protein	Bos taurus	72-82
2909518-8	1989	The RYD region of H-CDR3 appeared to be central to its function, because substitution of the tyrosine with glycine increased the inhibitory potency of the peptide by 10-fold, while replacing the tyrosine with D-alanine or inverting the RYD sequence sharply reduced the inhibitory potency.	Glycine	107-114	CDR3	Homo sapiens	20-24
2736257-4	1989	Utilization of radioactively labelled adrenodoxin, chemical cleavage of cytochrome P-450SCC from cross-linked complex with o-iodosobenzoic acid and HPLC for separation of peptides allow us to conclude that the complex of cytochrome P-450SCC with adrenodoxin was cross-linked through two amino acid sequences of cytochrome P-450SCC-Leu-88-Thr-107 and Leu-368-Gly-416.	Glycine	358-361	cholesterol side-chain cleavage enzyme, mitochondrial	Bos taurus	72-91
2736257-4	1989	Utilization of radioactively labelled adrenodoxin, chemical cleavage of cytochrome P-450SCC from cross-linked complex with o-iodosobenzoic acid and HPLC for separation of peptides allow us to conclude that the complex of cytochrome P-450SCC with adrenodoxin was cross-linked through two amino acid sequences of cytochrome P-450SCC-Leu-88-Thr-107 and Leu-368-Gly-416.	Glycine	358-361	cholesterol side-chain cleavage enzyme, mitochondrial	Bos taurus	221-240
2736257-4	1989	Utilization of radioactively labelled adrenodoxin, chemical cleavage of cytochrome P-450SCC from cross-linked complex with o-iodosobenzoic acid and HPLC for separation of peptides allow us to conclude that the complex of cytochrome P-450SCC with adrenodoxin was cross-linked through two amino acid sequences of cytochrome P-450SCC-Leu-88-Thr-107 and Leu-368-Gly-416.	Glycine	358-361	cholesterol side-chain cleavage enzyme, mitochondrial	Bos taurus	221-240
2489233-4	1989	Although inhibitors of the enkephalin degrading puromycin-insensitive, bestatin-sensitive aminopeptidase (possibly aminopeptidase M) their action is weak (IC50 = 32 microM leucine, 536 microM, glycine) and they might be considered to have a direct antinociceptive effect on opioid receptors.	Glycine	193-200	alanyl aminopeptidase, membrane	Homo sapiens	115-131
2787509-3	1989	Hydrin 1, found in Xenopus, has been identified as vasotocin C-terminally extended with the Gly-Lys-Arg sequence; hydrin 2, found in Rana, has been identified as vasotocin C-terminally extended with glycine.	Glycine	199-206	arginine vasopressin S homeolog	Xenopus laevis	162-171
2504572-10	1989	The "CAGY" sequence, or the Cys-Ala-Gly-Tyr quartet of amino acids encoded by exon II is present in every other glycoprotein beta-subunit sequenced thus far, is altered in rat FSH-beta, with the Ala residue replaced by Glu.	Glycine	36-39	follicle stimulating hormone subunit beta	Rattus norvegicus	176-184
2525104-3	1989	Here, the ability of the cell-attachment sequence of fibronectin, Arg-Gly-Asp-Ser (RGDS), to promote this process was studied.	Glycine	70-73	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	83-87
16453880-2	1989	), the glycine-rich wall protein GRP 1.8 is specifically synthesized in protoxylem tracheary elements of the vascular system.	Glycine	7-14	glycine-rich protein A3-like	Nicotiana tabacum	33-36
2712830-1	1989	Fibronectin, von Willebrand factor, and fibrinogen each bind to the glycoprotein IIb-IIIa complex on activated platelets via an arg-gly-asp-ser (RGDS) sequence present within the adhesive proteins.	Glycine	68-71	ral guanine nucleotide dissociation stimulator	Homo sapiens	145-149
2500135-3	1989	As with almost all reported gonadotropin alpha-subunits, NH2-terminal heterogeneity was found in the porcine FSH alpha-subunit (FSH alpha), starting with residue Phe (1), Asp (3), Gly (4), or Thr (7).	Glycine	180-183	glycoprotein hormones, alpha polypeptide	Homo sapiens	109-137
2494191-8	1989	Since cleavage in the hybrid protein occurred after glycine 25, which is derived from [2-lys,3-arg]P450IIC2, cytochrome P450 sequences COOH terminal to the cleavage site must decrease cleavage efficiency.	Glycine	52-59	cytochrome P-450	Oryctolagus cuniculus	109-124
2497500-1	1989	Intracisternal injection of thyrotropin-releasing hormone (TRH)-Gly (pGlu-His-Pro-Gly) produced a dose-dependent (1-100 micrograms) stimulation of gastric acid secretion in urethane-anesthetized rats implanted acutely with a gastric fistula.	Glycine	64-67	thyrotropin releasing hormone	Rattus norvegicus	28-57
2537814-1	1989	The lipoamide dehydrogenase of the glycine decarboxylase complex was purified to homogeneity (8 U/mg) from cells of the anaerobe Eubacterium acidaminophilum that were grown on glycine.	Glycine	35-42	dihydrolipoamide dehydrogenase	Homo sapiens	4-27
2497500-1	1989	Intracisternal injection of thyrotropin-releasing hormone (TRH)-Gly (pGlu-His-Pro-Gly) produced a dose-dependent (1-100 micrograms) stimulation of gastric acid secretion in urethane-anesthetized rats implanted acutely with a gastric fistula.	Glycine	64-67	thyrotropin releasing hormone	Rattus norvegicus	59-62
2497500-4	1989	Thereafter, TRH values are returned to basal levels at 75 min after the injection, whereas TRH-Gly concentrations remain significantly elevated throughout the 2-h period of measurement.	Glycine	95-98	thyrotropin releasing hormone	Rattus norvegicus	91-94
2497500-6	1989	Medullary coronal sections containing the dorsal vagal complex and the raphe nucleus revealed increased content of TRH-Gly, but not TRH, 40 min after administration of TRH-Gly at an intracisternal dose effective in stimulating gastric acid secretion (100 micrograms).	Glycine	119-122	thyrotropin releasing hormone	Rattus norvegicus	115-118
2497500-8	1989	These data suggest that the intracisternal TRH-Gly-induced stimulation of gastric acid secretion is not related to its conversion to TRH in the CSF, or direct activation of TRH receptors in the medulla.	Glycine	47-50	thyrotropin releasing hormone	Rattus norvegicus	43-46
2521674-8	1989	It is of interest that nsP4 contains the Gly-Asp-Asp motif characteristic of a number of viral replicases, and this, together with the fact that all RNA synthesis in ts6-infected cells and, to a lesser extent, in ts110-infected cells shut off when the cells were shifted from a permissive to a nonpermissive temperature, suggests that nsP4 is the virus polymerase.	Glycine	41-44	serine protease 57	Homo sapiens	23-27
3204521-1	1988	The glycine amide of tolmetin sodium (TGA) functions as a prodrug and was demonstrated to be more potent than the parent compound as an inhibitor of developing and established adjuvant arthritis in the female Lewis rat.	Glycine	4-11	T-box transcription factor 1	Homo sapiens	38-41
2624182-1	1989	We have cloned and sequenced a full length cDNA for HPRT cDNA for HPRTYale isolated from Lesch-Nyhan subject and identified a single nucleotide substitution which results in amino acid substitution of glycine to arginine.	Glycine	201-208	hypoxanthine phosphoribosyltransferase 1	Homo sapiens	52-56
3057136-1	1988	The relative amount of L-arginine:glycine amidinotransferase (transamidinase) protein in kidneys from rats fed a complete purified diet with and without the addition of creatine and/or glycine was determined by a monoclonal antibody-immunosorbent inhibition assay.	Glycine	34-41	glycine amidinotransferase	Rattus norvegicus	62-76
2497688-4	1989	To identify the TRH precursor in the rat hypothalamus, an antiserum was raised against the synthetic decapeptide sequence, Cys-Lys-Arg-Gln-His-Pro-Gly-Lys-Arg-Cys.	Glycine	147-150	thyrotropin releasing hormone	Rattus norvegicus	16-19
2903914-5	1988	In addition, in animals pretreated with a subconvulsive dose of strychnine to block strychnine-sensitive glycine receptors (Gly1), glycine enhances, rather than inhibits, NMDA-induced convulsions.	Glycine	105-112	threonine aldolase 1	Mus musculus	124-128
2462607-0	1989	CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide.	Glycine	52-55	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	0-3
2491890-2	1989	In the rat lens assay, several derivatives of 5 display greater inhibitory activity than the corresponding glycines 1, suggesting that N-phenyl substitution enhances affinity for aldose reductase.	Glycine	107-115	aldo-keto reductase family 1 member B1	Rattus norvegicus	179-195
2844265-3	1988	A quantitative assay for renal dipeptidase was developed which measures the rate of release of glycine from glycylpeptides by pre-column derivatization of the amino acid with phenylisothiocyanate followed by high-performance liquid chromatography.	Glycine	95-102	dipeptidase 1	Homo sapiens	25-42
2491890-7	1989	The anthranilates 7 generally are less active than the glycines 1, demonstrating that direct incorporation of an aromatic ring in the glycine side chain may result in a decrease in affinity for aldose reductase.	Glycine	55-63	aldo-keto reductase family 1 member B1	Rattus norvegicus	194-210
2456309-3	1988	After treatment with pyroglutamyl aminopeptidase, N-terminal sequencing indicated that Gln74 of MBP formed the N-terminal residue of peptide C. A rabbit antiserum was raised to a synthetic peptide containing the sequence Pyroglu-Lys-Ser-His-Gly-Arg, corresponding to the first six residues of peptide C. By immunoblotting this serum reacted with peptide C but not with intact MBP.	Glycine	241-244	myelin basic protein	Homo sapiens	96-99
2491890-7	1989	The anthranilates 7 generally are less active than the glycines 1, demonstrating that direct incorporation of an aromatic ring in the glycine side chain may result in a decrease in affinity for aldose reductase.	Glycine	55-62	aldo-keto reductase family 1 member B1	Rattus norvegicus	194-210
2501768-3	1989	TRH-Gly-IR and TRH-IR were detected in all of these tissues.	Glycine	4-7	thyrotropin releasing hormone	Rattus norvegicus	0-3
3395333-1	1988	Glycine decarboxylase, a constituent of the glycine cleavage system, in patients with either nonketotic or ketotic hyperglycinemia (NKH and KH) was examined using an anti-chicken glycine decarboxylase antibody.	Glycine	44-51	glycine decarboxylase	Homo sapiens	0-21
3187957-6	1988	Shear-induced platelet aggregation was inhibited by monoclonal antibody to GPIIb/IIIa (1 microgram/ml) and synthetic peptide, Arg-Gly-Asp-Ser (RGDS) (1 mM).	Glycine	130-133	ral guanine nucleotide dissociation stimulator	Homo sapiens	143-147
3294332-0	1988	Complement receptor type 3 (CR3) binds to an Arg-Gly-Asp-containing region of the major surface glycoprotein, gp63, of Leishmania promastigotes.	Glycine	49-52	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	0-31
3137519-1	1988	Although dietary leucine restriction and supplemental glycine are used to treat patients with isovaleric acidemia [deficient isovaleryl-CoA-dehydrogenase (E.C.1.3.99.10)], little quantitative information is available regarding their optimum relationship.	Glycine	54-61	isovaleryl-CoA dehydrogenase	Homo sapiens	125-153
3072564-8	1988	In the crystal structure of insulin a hydrogen bond bridges the alpha-nitrogen of A21 with the backbone carbonyl of B23 glycine.	Glycine	120-127	insulin	Sus scrofa	28-35
3169039-6	1988	The formation of both neurite classes on either pFN or CTB was completely inhibited by low concentrations of an RGDS (Arg-Gly-Asp-Ser) peptide in the medium of cultures, indicating the significance of pFN"s binding to cell surface integrin or ganglioside GM1"s possible interaction with integrin for mediating the differentiative process.	Glycine	122-125	ral guanine nucleotide dissociation stimulator	Homo sapiens	112-116
2834873-14	1988	The nsP4s of these five alphaviruses are highly conserved, sharing 71-76% amino acid sequence similarity, and all five contain the Gly-Asp-Asp motif found in many RNA virus replicases.	Glycine	131-134	serine protease 57	Homo sapiens	4-8
3282511-0	1988	Rapid and transient induction of c-fos, c-myc and c-Ha-ras in rat liver following glycine administration.	Glycine	82-89	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	40-45
3282511-4	1988	The rapid rise and decline in the mRNA levels of c-fos, c-myc and c-Ha-ras in response to glycine is of significance because in response to a wide variety of growth stimuli, these proto-oncogenes exhibit a temporal sequence in their expression; for example, the expression of c-fos precedes that of c-myc, which in turn precedes the increased expression of c-Ha-ras.	Glycine	90-97	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	56-61
3282511-4	1988	The rapid rise and decline in the mRNA levels of c-fos, c-myc and c-Ha-ras in response to glycine is of significance because in response to a wide variety of growth stimuli, these proto-oncogenes exhibit a temporal sequence in their expression; for example, the expression of c-fos precedes that of c-myc, which in turn precedes the increased expression of c-Ha-ras.	Glycine	90-97	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	299-304
2826431-8	1987	The 1H NMR spectrum of peaks representing amide hydrogens of the carboxyl-terminal Arg-74, Gly-75, and Gly-76 of the processed mono-ubiquitin was identical with that of human ubiquitin.	Glycine	91-94	ubiquitin	Saccharomyces cerevisiae S288C	132-141
2826431-8	1987	The 1H NMR spectrum of peaks representing amide hydrogens of the carboxyl-terminal Arg-74, Gly-75, and Gly-76 of the processed mono-ubiquitin was identical with that of human ubiquitin.	Glycine	91-94	ubiquitin	Saccharomyces cerevisiae S288C	175-184
2826431-8	1987	The 1H NMR spectrum of peaks representing amide hydrogens of the carboxyl-terminal Arg-74, Gly-75, and Gly-76 of the processed mono-ubiquitin was identical with that of human ubiquitin.	Glycine	103-106	ubiquitin	Saccharomyces cerevisiae S288C	132-141
2826431-8	1987	The 1H NMR spectrum of peaks representing amide hydrogens of the carboxyl-terminal Arg-74, Gly-75, and Gly-76 of the processed mono-ubiquitin was identical with that of human ubiquitin.	Glycine	103-106	ubiquitin	Saccharomyces cerevisiae S288C	175-184
2825199-4	1987	As a result, the 128th amino acid, aspartic acid, was replaced with glycine (GAT to GGT).	Glycine	68-75	gamma-glutamyltransferase light chain 5 pseudogene	Homo sapiens	84-87
3427074-5	1987	The S1 binding pocket is bounded by Gly-216 and Ser-226, making this pocket intermediate in size between chymotrypsins and elastase 1 or protease E, consistent with the substrate specificity of elastase 2 for long-chain aliphatic or aromatic amino acids.	Glycine	36-39	elastase, neutrophil expressed	Homo sapiens	194-204
3301403-4	1987	The glycines at A1, B8 and B23 allow the chain to assume the characteristic tertiary interactions of the insulin fold and although polypeptide chains are shorter at the COOH-termini of the A and B chains and extended at the NH2-terminus of the B chain, the insulin-like tertiary structure can still be assumed.	Glycine	4-12	nucleophosmin 1	Homo sapiens	27-30
3148933-5	1987	The carboxy-terminal glycine was subsequently amidated by PAM (peptidylglycine-alpha-amidating-monooxygenase), an enzyme which was isolated and characterized from fresh bovine pituitaries.	Glycine	21-28	peptidylglycine alpha-amidating monooxygenase	Bos taurus	58-61
2501768-4	1989	Highly significant positive correlations between whole blood TRH-Gly-IR levels and the corresponding serum TSH values (p less than 0.01), whole blood TRH-IR versus serum TSH (p less than 0.01) and whole blood TRH-Gly-IR versus whole blood TRH-IR (p less than 0.01) are consistent with cosecretion of TRH and TRH precursor peptides into the circulation.	Glycine	65-68	thyrotropin releasing hormone	Rattus norvegicus	61-64
2501768-6	1989	and hypothyroid rats had 4-fold higher whole blood TRH-Gly-IR levels compared to euthyroid controls (p less than 0.0005).	Glycine	55-58	thyrotropin releasing hormone	Rattus norvegicus	51-54
2501768-7	1989	Injection of TRH into euthyroid rats significantly increased the TRH-Gly-IR concentration in the hypothalamus, anterior and posterior pituitary and thyroid.	Glycine	69-72	thyrotropin releasing hormone	Rattus norvegicus	13-16
2501768-7	1989	Injection of TRH into euthyroid rats significantly increased the TRH-Gly-IR concentration in the hypothalamus, anterior and posterior pituitary and thyroid.	Glycine	69-72	thyrotropin releasing hormone	Rattus norvegicus	65-68
2501768-8	1989	The increase in blood TRH-Gly-IR following intravenous TRH may be due, in part, to partial saturation of TRH-degrading enzymes in blood and cell membranes.	Glycine	26-29	thyrotropin releasing hormone	Rattus norvegicus	22-25
2501768-8	1989	The increase in blood TRH-Gly-IR following intravenous TRH may be due, in part, to partial saturation of TRH-degrading enzymes in blood and cell membranes.	Glycine	26-29	thyrotropin releasing hormone	Rattus norvegicus	55-58
2501768-8	1989	The increase in blood TRH-Gly-IR following intravenous TRH may be due, in part, to partial saturation of TRH-degrading enzymes in blood and cell membranes.	Glycine	26-29	thyrotropin releasing hormone	Rattus norvegicus	55-58
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	4-7	thyrotropin releasing hormone	Rattus norvegicus	0-3
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	4-7	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	4-7	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	4-7	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	0-3
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	0-3
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	88-91
2501768-10	1989	TRH-Gly levels of pooled pituitary and thyroid extracts quantitated by a combination of TRH-Gly RIA and high performance liquid chromatography (HPLC) revealed several-fold increases following incubation at 60 degrees C. Heating at this temperature may block the alpha-amidation activity in extra-hypothalamic tissues but not the "trypsin-like" enzymes which cleave prepro-TRH into TRH-Gly-immunoreactive peptides.	Glycine	92-95	thyrotropin releasing hormone	Rattus norvegicus	88-91
3148933-5	1987	The carboxy-terminal glycine was subsequently amidated by PAM (peptidylglycine-alpha-amidating-monooxygenase), an enzyme which was isolated and characterized from fresh bovine pituitaries.	Glycine	21-28	peptidylglycine alpha-amidating monooxygenase	Bos taurus	63-108
3197838-6	1988	The sequence of bovine angiogenin contains the cell recognition tripeptide Arg-Gly-Asp which is not present in the human protein.	Glycine	79-82	angiogenin	Homo sapiens	23-33
3493352-2	1987	Myristic acid is normally esterified through an amide linkage to a glycine residue at the amino terminus of the Mason-Pfizer monkey virus gag gene products.	Glycine	67-74	Pr78	Mason-Pfizer monkey virus	138-141
3141416-2	1988	Rat thyrotropin-releasing hormone prohormone (pro-TRH) contains five separate copies of the TRH progenitor sequence: Gln-His-Pro-Gly.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	46-53
3141416-2	1988	Rat thyrotropin-releasing hormone prohormone (pro-TRH) contains five separate copies of the TRH progenitor sequence: Gln-His-Pro-Gly.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	50-53
2848850-7	1988	Attachment of all four cell types is also markedly inhibited by the synthetic peptides gly-arg-gly-asp-ser-pro (GRG-DSP) and gly-arg-gly-asp-ala-cys (GRGDAC) but not by the control peptide gly-arg-gly-glu-ser-pro (GRG-ESP).	Glycine	87-90	protein tyrosine phosphatase receptor type V, pseudogene	Homo sapiens	218-221
2846539-4	1988	The codons for the two presumed active sites of protein disulfide isomerase, each a Cys-Gly-His-Cys sequence, are located 12 base pairs from the beginning of exons 2 and 9.	Glycine	88-91	prolyl 4-hydroxylase subunit beta	Homo sapiens	48-75
2950119-2	1987	To determine if the minimum cellular adhesion receptor recognition signal Arg-Gly-Asp-Ser (RGDS) is sufficient to promote FC and MFB formation, rat (NRK), hamster (Nil 8), and mouse (Balb/c 3T3) fibroblasts in serum-free media were plated on substrates derivatized with small synthetic peptides containing RGDS.	Glycine	78-81	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	91-95
3189554-1	1988	Glycine-extended gastrin, the immediate precursor of bioactive (i.e., carboxyamidated) gastrin, was recently identified in antral tissue and in peripheral blood.	Glycine	0-7	gastrin	Sus scrofa	17-24
3091598-9	1986	Coupled reactions of purified bovine aminoacetone synthetase and porcine L-threonine dehydrogenase demonstrated the interconversion of threonine and glycine.	Glycine	149-156	L-threonine dehydrogenase	Bos taurus	73-98
3145192-4	1988	The mutated RAS2 gene in TS1 cells encoded a protein with the glycines at positions 82 and 84 replaced by serine and arginine respectively.	Glycine	62-70	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	12-16
3189554-1	1988	Glycine-extended gastrin, the immediate precursor of bioactive (i.e., carboxyamidated) gastrin, was recently identified in antral tissue and in peripheral blood.	Glycine	0-7	gastrin	Sus scrofa	87-94
3004916-2	1986	Peptidylglycine alpha-amidating monooxygenase (PAM) is the enzyme responsible for the generation of mature COOH-terminal alpha-amidated peptides from COOH-terminal glycine-extended peptides, and this enzyme requires ascorbate for full activity in vitro.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Mus musculus	47-50
3189554-3	1988	To determine whether the secretion of glycine-extended gastrin from the antral G-cell is regulated, meal-induced release was examined.	Glycine	38-45	gastrin	Sus scrofa	55-62
3069842-3	1988	Propioxatins A and B are inhibitors of enkephalinase B, which hydrolyzes enkephalin at the Gly-Gly bond.	Glycine	91-94	dipeptidyl peptidase 3	Homo sapiens	39-54
3189554-7	1988	The results demonstrate that glycine-extended gastrin is released in a regulated manner from antral G-cells and furthermore the component pattern is identical in mucosa and blood.	Glycine	29-36	gastrin	Sus scrofa	46-53
3069842-3	1988	Propioxatins A and B are inhibitors of enkephalinase B, which hydrolyzes enkephalin at the Gly-Gly bond.	Glycine	95-98	dipeptidyl peptidase 3	Homo sapiens	39-54
2460346-1	1988	An antibody population recognizing the sequence Arg-Gly-Asp-Ser (RGDS) in fibronectin, anti-(RGDS)N, was isolated by immunoadsorption.	Glycine	52-55	ral guanine nucleotide dissociation stimulator	Homo sapiens	65-69
3521594-1	1986	Incubation of pig desoctapeptide-(B23-30)-insulin with trypsin in solvent systems consisting of dimethyl sulphoxide, butane-1,4-diol and Tris buffer resulted in the formation of an extra peptide bond between Arg-B22 and Gly-A1 in the DOPI molecule.	Glycine	220-223	insulin	Sus scrofa	42-49
2460346-1	1988	An antibody population recognizing the sequence Arg-Gly-Asp-Ser (RGDS) in fibronectin, anti-(RGDS)N, was isolated by immunoadsorption.	Glycine	52-55	ral guanine nucleotide dissociation stimulator	Homo sapiens	93-97
3287376-2	1988	A pol1 temperature-sensitive mutation, encoding a DNA-polymerase-primase complex with altered stability, has a single base-pair substitution that changes the glycine at position 493 to a positively charged arginine.	Glycine	158-165	DNA-directed DNA polymerase alpha catalytic subunit POL1	Saccharomyces cerevisiae S288C	2-6
3929378-1	1985	A rabbit antiserum to a peptide sequence present in the precursor for thyrotropin-releasing hormone (proTRH), deduced from cloned amphibian-skin complementary DNA, was raised by immunization with the synthetic decapeptide Cys-Lys-Arg-Gln-His-Pro-Gly-Lys-Arg-Cys (proTRH-SH).	Glycine	246-249	thyrotropin releasing hormone	Rattus norvegicus	70-99
3186740-0	1988	Ligand binding to synthetic mutant myoglobin (His-E7----Gly): role of the distal histidine.	Glycine	56-59	myoglobin	Physeter catodon	35-44
3382697-5	1988	The high frequency and clustering of proline and glycine residues in estrogen receptor, progesterone receptor and glucose-6-phosphate dehydrogenase suggests that the translating ribosomes may slow down during synthesis of these proteins due to limiting levels of these tRNAs in E2-deprived uteri.	Glycine	49-56	progesterone receptor	Homo sapiens	88-109
2966812-5	1988	The cytoadhesive tetrapeptide portion of fibronectin, Arg-Gly-Asp-Ser (250-1,000 micrograms/ml), released 1.94 +/- 0.10 micrograms/ml of elastase from 10(7) neutrophils, in contrast to the lack of release by the control hexapeptide, Arg-Gly-Tyr-Ser-Leu-Gly.	Glycine	58-61	elastase, neutrophil expressed	Homo sapiens	137-145
3372531-2	1988	In the present studies, high levels of peptidylglycine alpha-amidating monooxygenase (PAM), which catalyzes the formation of bioactive alpha-amidated peptides from their glycine-extended precursors, have been found in particulate fractions from bovine and rat heart atrium; only low levels of PAM activity were present in soluble fractions.	Glycine	47-54	peptidylglycine alpha-amidating monooxygenase	Bos taurus	86-89
16726054-2	1985	Groups of ewes were initially treated on Day 2, 10 or 14 of the oestrous cycle with 10 mug GnRH analogue (D-Ser(Bu(t)) 6 des Gly GnRH ethylamide) per ewe per day for 14 days.	Glycine	125-128	gonadotropin releasing hormone 1	Homo sapiens	91-95
2826431-11	1987	In the pyrophosphate exchange assay with isolated ubiquitin activating enzyme E1, they were also equally reactive, confirming that the expressed and processed ubiquitin contained an intact carboxyl-terminal Gly-76.	Glycine	207-210	ubiquitin	Saccharomyces cerevisiae S288C	159-168
3245132-6	1988	In this sequence, the 27 NH2-terminal amino acids determined by sequence analysis of protein p37 are preceded by a stretch of 132 amino acids residues, indicating that protein p37 is synthesized as a polypeptide of higher molecular weight and then post-translationally processed by cleavage of a Gly-Ala bond.	Glycine	296-299	nucleoporin 37	Homo sapiens	176-179
3480361-9	1987	From the above results, CS, as a dehydropeptidase-I inhibitor apparently caused increases in some peptides consisting mainly of Asp, Glu, Gly and Ala in patients with impaired renal function.	Glycine	138-141	dipeptidase 1	Homo sapiens	33-51
3271105-6	1988	Four corrections to the amino acid sequence were made, which were confirmed later by sequence analysis of the proteinase K gene: a deletion of one glycine in position 80; a change of sequence in position 207-208 and insertions of the dipeptide 210-211 and of residue 270.	Glycine	147-154	endogenous retrovirus group K member 7	Homo sapiens	110-120
3620493-2	1987	We show here that ASF-like proteins are produced in the rat during intestinal secretion triggered by intake of a 500 mg dose of mannose, sorbitol, glycine or alanine.	Glycine	147-154	proteasome 26S subunit ubiquitin receptor, non-ATPase 4	Rattus norvegicus	18-21
3280807-2	1988	Mutations at the suf12 locus were isolated in Saccharomyces cerevisiae as extragenic suppressors of +1 frameshift mutations in glycine (GGX) and proline (CCX) codons, as well as UGA and UAG nonsense mutations.	Glycine	127-134	translation termination factor GTPase eRF3	Saccharomyces cerevisiae S288C	17-22
6504240-1	1984	In vitro synthesis of myelin proteolipid protein (PLP) was explored at different ages using rat brain total homogenates, incubated for 30 min with [3H]glycine.	Glycine	151-158	proteolipid protein 1	Rattus norvegicus	22-48
6504240-1	1984	In vitro synthesis of myelin proteolipid protein (PLP) was explored at different ages using rat brain total homogenates, incubated for 30 min with [3H]glycine.	Glycine	151-158	proteolipid protein 1	Rattus norvegicus	50-53
6609366-5	1984	A glycine at residue 12 decreased the amount of pp21 to 14% of total p21, and a valine at residue 12 dramatically increased this value to 50%.	Glycine	2-9	transcription elongation factor A like 1	Homo sapiens	48-52
6609366-5	1984	A glycine at residue 12 decreased the amount of pp21 to 14% of total p21, and a valine at residue 12 dramatically increased this value to 50%.	Glycine	2-9	transcription elongation factor A like 1	Homo sapiens	49-52
3693395-9	1987	Substitution of either an acidic (aspartate) or a "helix-breaking" (glycine) amino acid residue for arginine 23 of the leader inhibits formation of both iOTC and OTC, without affecting translocation.	Glycine	68-75	ornithine transcarbamylase	Rattus norvegicus	154-157
6609366-6	1984	In vitro, the valine form of p21 had 2.4- and 2.7-fold greater autophosphorylating activity than the glycine and arginine forms of p21, respectively, using [gamma-32P]GTP as phosphate donor, but the three p21 species had similar Km values for GTP (0.20-0.27 microM).	Glycine	101-108	transcription elongation factor A like 1	Homo sapiens	29-32
3496337-9	1987	We conclude that the peptidyl bond of the conserved glycine residue in human cystatin C and chicken cystatin probably is part of a substrate-like inhibitory reactive site of these cysteine proteinase inhibitors of the cystatin superfamily and that this may be true also for other inhibitors of this superfamily.	Glycine	52-59	cystatin C	Homo sapiens	77-87
3109876-1	1987	The sequence of rat hypothalamic pro-TRH, deduced by sequencing of cDNA, contains five copies of the TRH progenitor sequence Gln-His-Pro-Gly flanked by paired basic amino acid sequences.	Glycine	137-140	thyrotropin releasing hormone	Rattus norvegicus	33-40
6582480-4	1984	Separation of their digests by high-performance reverse-phase chromatography and by two-dimensional paper chromatography and electrophoresis revealed that ALDH2 contained a peptide sequence of -Glu-Leu-Gly-Glu-Ala-Gly-Leu-Gln-Ala-Asn-Val-Gln-Val-Lys- and that the glutamine adjacent to lysine was substituted by lysine in CRM.	Glycine	202-205	aldehyde dehydrogenase 2 family member	Homo sapiens	155-160
3116140-6	1987	Hypothyroidism induced by PTU significantly increased TRH-IR and TRH-Gly-IR levels in prostate and testis and reduced these levels in epididymis but did not affect the serum concentrations of testosterone compared with those of controls.	Glycine	69-72	thyrotropin releasing hormone	Rattus norvegicus	65-68
3116140-7	1987	Corresponding changes in TRH and TRH-Gly in the rat prostate were established by high-pressure liquid chromatography.	Glycine	37-40	thyrotropin releasing hormone	Rattus norvegicus	33-36
3036276-1	1987	Human fibrinogen has an Arg-Gly-Asp-Ser (RGDS) sequence at residues 572-575 of its A alpha-chain.	Glycine	28-31	ral guanine nucleotide dissociation stimulator	Homo sapiens	41-45
3109876-1	1987	The sequence of rat hypothalamic pro-TRH, deduced by sequencing of cDNA, contains five copies of the TRH progenitor sequence Gln-His-Pro-Gly flanked by paired basic amino acid sequences.	Glycine	137-140	thyrotropin releasing hormone	Rattus norvegicus	37-40
2956269-4	1987	The RGDS tetrapeptide (arg-gly-asp-ser) from the cell attachment domain of fibronectin can specifically block attachment and outgrowth on both fibronectin- and laminin-coated substrates.	Glycine	27-30	ral guanine nucleotide dissociation stimulator	Homo sapiens	4-8
2888016-7	1987	The deduced amino acid sequence of E. histolytica actin resembles both cytoplasmic and muscle actins and has an unusual N-terminal glycine residue.	Glycine	131-138	EHI_142730	Entamoeba histolytica HM-1:IMSS	50-55
3109909-2	1987	Peptides related to TRH were detected by trypsin digestion and radioimmunoassay with an antibody to TRH or an antibody raised against the pentapeptide Glp-His-Pro-Gly-Lys.	Glycine	163-166	thyrotropin releasing hormone	Rattus norvegicus	20-23
6652134-2	1983	CPK-model was built and then conformational computations for (Gly-Ala-Hyp)n and (Gly-Ala-Ala)n were performed.	Glycine	62-65	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	Homo sapiens	0-3
3103685-3	1987	Glycine transport appears to be shared by both systems A and ASC in P388 cells.	Glycine	0-7	steroid sulfatase	Mus musculus	61-64
6315008-10	1983	On further fragmentation with cathepsin D, a dodecapeptide containing ADP-ribose moiety was isolated whose structure was determined as: Asp-Glu-Glu-Leu-His-Arg-Gly-Tyr-Arg*-Asp-Arg-Tyr.	Glycine	160-163	cathepsin D	Homo sapiens	30-41
3815805-3	1987	GAA in the ultrafiltrate was subsequently hydrolyzed by guanidinoacetate amidinohydrolase (EC 3.5.3.2) to glycine and urea.	Glycine	106-113	alpha glucosidase	Homo sapiens	0-3
3099113-2	1986	A species specific protein with repetitive -Gln-His-Pro-Gly- sequences, which are flanked on the N- and C-terminus by paired basic residues, has been shown to be the source of TRH in frog skin and rat hypothalamus.	Glycine	56-59	thyrotropin releasing hormone	Rattus norvegicus	176-179
6873388-3	1983	During the suppression of all but the "a"-wave ERG components with glycine, the early negative potential alone is preserved in the central structures of the visual system.	Glycine	67-74	transcriptional regulator ERG	Oryctolagus cuniculus	47-50
3031652-0	1987	pen repeat sequences are GGN clusters and encode a glycine-rich domain in a Drosophila cDNA homologous to the rat helix destabilizing protein.	Glycine	51-58	gametogenetin	Rattus norvegicus	25-28
3024151-0	1986	Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.	Glycine	89-92	cysteine-rich secretory protein 3	Rattus norvegicus	42-54
3024151-0	1986	Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.	Glycine	89-92	secreted phosphoprotein 1	Rattus norvegicus	56-67
3024151-9	1986	The results show that the Arg-Gly-Asp sequence also confers cell-binding properties on bone-specific sialoprotein.	Glycine	30-33	cysteine-rich secretory protein 3	Rattus norvegicus	101-113
2432837-11	1986	Additionally, hydroxylamine cleavage of an Asn-Gly bond in prefetuin localized one of the N-linked carbohydrate side chains to the middle of the polypeptide chain of native fetuin.	Glycine	47-50	alpha-2-HS-glycoprotein	Oryctolagus cuniculus	62-68
3524679-1	1986	Ferredoxin which had been modified with glycine ethylester in the presence of a water-soluble carbodiimide to the extent of one carboxyl-group modified per ferredoxin was subjected to peptide mapping in an attempt to locate the site(s) of modification.	Glycine	40-47	ferredoxin reductase	Homo sapiens	0-10
6304695-1	1983	Thiorphan, N-[(R,S)-3-mercapto-2-benzylpropanoyl]glycine is a highly potent inhibitor (Ki = 3.5 nM) of "enkephalinase," a metalloendopeptidase cleaving the Gly-Phe bond (positions 3 and 4) of enkephalins in brain tissue.	Glycine	156-159	membrane metallo endopeptidase	Mus musculus	104-117
2835765-11	1986	From predictions on the structure of these conserved blocks, we have proposed that the location of a substrate binding site within RR1 is centered on three conserved glycine residues in a region which is predicted to adopt a beta-sheet/turn/alpha-helical structure; this approximates to the structure for ADP nucleotide binding folds.	Glycine	166-173	ribonucleotide reductase catalytic subunit M1	Homo sapiens	131-134
6572978-3	1983	Codon 24 in both the normal gene (GGT) and the beta+-thalassemia gene (GGA) encodes glycine.	Glycine	84-91	gamma-glutamyltransferase light chain 5 pseudogene	Homo sapiens	34-37
3912194-5	1985	Administration of enkephalinase inhibitors rapidly elicited marked decrease in Tyr-Gly-Gly immunoreactivity whereas bestatin, an aminopeptidase inhibitor, elicited 100% increase and captopril, an ACE inhibitor, was without significant effect.	Glycine	83-86	membrane metallo endopeptidase	Mus musculus	18-31
3015971-5	1986	MAGP is an acidic glycoprotein with a distinctive amino acid composition, being exceptionally rich in glutamic acid, rich in cystine, and low in glycine.	Glycine	145-152	microfibril associated protein 2	Bos taurus	0-4
4083898-10	1985	The finding that cytochrome P-450 and the 55-kDa protein were selectively retained by the affinity column and eluted with NaCl (2 M) and glycine (0.2 M, pH 3.0) and that this fraction contained aromatase activity upon reconstitution with purified NADPH-cytochrome P-450 reductase and phospholipid, is indicative that the 55-kDa protein is indeed cytochrome P-450AROM.	Glycine	137-144	membrane protein, palmitoylated	Mus musculus	42-48
16453478-9	1983	This result implicates mutation of residue 5332 in the temperature sensitivity of viral assembly (by altering the structure of the RNA close to the assembly origin) and/or local lesion spreading (via a radical Arg to Gly substitution in p30 or its derivatives).	Glycine	217-220	centromere protein V	Homo sapiens	237-240
3090936-2	1986	The release of CO2 from glycine in intact mitochondria isolated from dark-grown and nonphotosynthetic tissues was sensitive to inhibitors of mitochondrial electron transport, glycine transport, and glycine decarboxylase activities.	Glycine	24-31	glycine dehydrogenase (decarboxylating), mitochondrial	Solanum tuberosum	198-219
7153213-0	1982	The mitochondrial glycine cleavage system: inactivation of glycine decarboxylase as a side reaction of the glycine decarboxylation in the presence of aminomethyl carrier protein.	Glycine	18-25	glycine decarboxylase	Homo sapiens	59-80
7153213-1	1982	Glycine decarboxylase, tentatively called P-protein, was inactivated when it was incubated with glycine in the presence of the aminomethyl carrier protein, called H-protein.	Glycine	96-103	glycine decarboxylase	Homo sapiens	0-21
7153213-1	1982	Glycine decarboxylase, tentatively called P-protein, was inactivated when it was incubated with glycine in the presence of the aminomethyl carrier protein, called H-protein.	Glycine	96-103	OCA2 melanosomal transmembrane protein	Homo sapiens	42-51
7153213-4	1982	Such a spectral change and concomitant inactivation of the P-protein could be completely prevented by the addition of sodium bicarbonate, which initiates the glycine-CO2 exchange in the reaction mixture.	Glycine	158-165	OCA2 melanosomal transmembrane protein	Homo sapiens	59-68
7153213-5	1982	The inactivated P-protein was associated with H-protein and the methylene carbon of glycine, but not the carboxyl carbon, in a manner not separable by gel filtration, although the molar ratios of those three components were not constant.	Glycine	84-91	OCA2 melanosomal transmembrane protein	Homo sapiens	16-25
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	117-124	OCA2 melanosomal transmembrane protein	Homo sapiens	24-33
2862917-1	1985	Kinetic studies of pig kidney dipeptidyl peptidase IV (dipeptidyl-peptide hydrolase, EC 3.4.14.5) were carried out using substrates possessing a side-chain of different length at the P2 position (or amino-terminal position in this case) such as Lys-, Arg-, Phe-, Met-, Ser-, His-, Glu- and Gly-Pro-pNA.	Glycine	290-293	dipeptidyl peptidase 4	Sus scrofa	30-53
4026327-2	1985	The neutral binding protein (pI 7.0), which has a high glycine content, is an analog of mammalian liver MBP (F-I).	Glycine	55-62	myelin basic protein	Homo sapiens	104-107
3090936-4	1986	This suggests that the differences in capacity to oxidize glycine reside with the glycine decarboxylase enzyme complex itself.	Glycine	58-65	glycine dehydrogenase (decarboxylating), mitochondrial	Solanum tuberosum	82-103
4038319-1	1985	Modification of the polypeptide anthopleurin-A with a carbodiimide and glycine ethyl ester leads to the addition of nearly two Gly to AP-A.	Glycine	127-130	glutamyl aminopeptidase	Homo sapiens	134-138
3086517-4	1986	Thus, it has been proposed that COOH-terminal glycine-extended TRH (TRH-Gly) may be the direct precursor to TRH.	Glycine	46-53	thyrotropin releasing hormone	Homo sapiens	63-66
3970979-2	1985	The greatest percentages of inhibition of TPA-induced epidermal ornithine decarboxylase activity were as follows: cysteine, 98%; tryptophan, 74%; methionine, 64%; phenylalanine, 51%; glycine, 44%; asparagine, 43%; glutamic acid, 42%; leucine, 40%; and arginine, 39%.	Glycine	183-190	ornithine decarboxylase 1	Homo sapiens	64-87
7041967-1	1982	The substrate specificity of a peptidase from anterior pituitaries that is capable of hydrolyzing luteinizing hormone-releasing hormone (LH-RH; less than Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) at the Tyr5-Gly6 peptide bond has been investigated by using inhibitors and model substrates.	Glycine	174-177	gonadotropin releasing hormone 1	Homo sapiens	98-135
7041967-1	1982	The substrate specificity of a peptidase from anterior pituitaries that is capable of hydrolyzing luteinizing hormone-releasing hormone (LH-RH; less than Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) at the Tyr5-Gly6 peptide bond has been investigated by using inhibitors and model substrates.	Glycine	174-177	gonadotropin releasing hormone 1	Homo sapiens	137-142
6790577-3	1981	The activities of glycine decarboxylase (P-protein) and the aminomethyl carrier protein (H-protein), two of the four protein components of the glycine cleavage system, were considerably reduced in both the liver and brain; the extent of reduction was greater in the H-protein.	Glycine	18-25	OCA2 melanosomal transmembrane protein	Homo sapiens	41-50
2989090-4	1985	Although this tRNA gene has an anticodon sequence of CCC, it has a striking homology (96%) with a human glycine tRNA which has an anticodon of GCC.	Glycine	104-111	guanylate cyclase 2C	Homo sapiens	143-146
3086517-4	1986	Thus, it has been proposed that COOH-terminal glycine-extended TRH (TRH-Gly) may be the direct precursor to TRH.	Glycine	46-53	thyrotropin releasing hormone	Homo sapiens	68-75
3086517-4	1986	Thus, it has been proposed that COOH-terminal glycine-extended TRH (TRH-Gly) may be the direct precursor to TRH.	Glycine	46-53	thyrotropin releasing hormone	Homo sapiens	68-71
3957924-3	1986	The low molecular weight polysialoglycoprotein obtained from the fertilized eggs accounted for about 85% of total polysialoglycoprotein and comprised glycotridecapeptides with a uniform peptide sequence which was determined to be Asp-Asp-Ala-Thr*-Ser*-Glu-Ala-Ala-Thr*-Gly-Pro-Ser-Gly, where * indicates the site of glycosylation.	Glycine	269-272	polysialoglycoprotein	Oncorhynchus mykiss	25-46
6090951-6	1984	These DNA sequences code for a protein of 92 amino acids in which the LHRH decapeptide is preceded by a signal peptide of 23 amino acids and followed by a Gly-Lys-Arg sequence, as expected for enzymatic cleavage of the decapeptide from its precursor and amidation of the carboxy-terminal of LHRH.	Glycine	155-158	gonadotropin releasing hormone 1	Homo sapiens	70-74
6435279-3	1984	By addition of glycine buffer to a final concentration of 2.0 M at 26 degrees C, the bulk of fibrinogen was precipitated while factor VIII remained in solution.	Glycine	15-22	cytochrome c oxidase subunit 8A	Homo sapiens	134-138
6435279-4	1984	Factor VIII was precipitated from the glycine supernatant by addition of solid sodium chloride.	Glycine	38-45	cytochrome c oxidase subunit 8A	Homo sapiens	7-11
6790577-8	1981	Partial inactivation of P-protein could result secondarily from impaired metabolism of glycine resulting from deficiency in the activity of H-protein.	Glycine	87-94	OCA2 melanosomal transmembrane protein	Homo sapiens	24-33
6790577-9	1981	However, the H-protein from the patient could stimulate the P-protein catalyzed exchange of the carboxyl carbon of glycine with 14CO2, although the specific activity of the purified H-protein from the patient was only 4% of that of control human H-protein.	Glycine	115-122	OCA2 melanosomal transmembrane protein	Homo sapiens	60-69
3957924-3	1986	The low molecular weight polysialoglycoprotein obtained from the fertilized eggs accounted for about 85% of total polysialoglycoprotein and comprised glycotridecapeptides with a uniform peptide sequence which was determined to be Asp-Asp-Ala-Thr*-Ser*-Glu-Ala-Ala-Thr*-Gly-Pro-Ser-Gly, where * indicates the site of glycosylation.	Glycine	281-284	polysialoglycoprotein	Oncorhynchus mykiss	25-46
6934522-4	1980	Dansyl chloride-treated PBP yielded a single dansylated amino acid residue (glycine).	Glycine	76-83	pro-platelet basic protein	Homo sapiens	24-27
3005352-9	1986	Glycine buffer wash was shown to reversibly remove more than 88% of bound hCG and, in freshly isolated cells, increased [125I]hCG binding by 100%.	Glycine	0-7	hypertrichosis 2 (generalised, congenital)	Homo sapiens	74-77
6249374-1	1980	Any one of five amino acis (alanine, asparagine, glutamine, glycine, and serine) is an essential requirement for the induction of ornithine decarboxylase (EC 4.1.1.17) in cultured chinese hamster ovary (CHO) cells maintained with a salts/glucose, medium.	Glycine	60-67	ornithine decarboxylase 1	Homo sapiens	130-153
6204743-4	1984	Continuous exposure to glycine (200 microM)-adenosine (100 microM)-thymidine (10 microM) (GAT), along with MTX, protected cells from MTX cytotoxicity by circumventing the requirement for tetrahydrofolate cofactors.	Glycine	23-30	glycine-N-acyltransferase	Mus musculus	90-93
6427768-0	1984	Glycine-directed peptide amidation: presence in rat brain of two enzymes that convert p-Glu-His-Pro-Gly-OH into p-Glu-His-Pro-NH2 (thyrotropin-releasing hormone).	Glycine	0-7	thyrotropin releasing hormone	Rattus norvegicus	131-160
6997872-7	1980	These results suggest that the antagonistic activity of a human insulin variant having leucine at position B24 or B25 can be assigned to the molecule with the sequence Gly-Leu-Phe-Tyr (residues B23-B26) in its active site.	Glycine	168-171	nucleophosmin 1	Homo sapiens	194-197
3005352-9	1986	Glycine buffer wash was shown to reversibly remove more than 88% of bound hCG and, in freshly isolated cells, increased [125I]hCG binding by 100%.	Glycine	0-7	hypertrichosis 2 (generalised, congenital)	Homo sapiens	126-129
3079917-3	1986	This protein contained five copies of the sequence Gln-His-Pro-Gly flanked by paired basic amino acids and could therefore generate five TRH molecules.	Glycine	63-66	thyrotropin releasing hormone	Rattus norvegicus	137-140
6244908-3	1980	The properties of 5"-nucleotidase were studied by eliminating the interference of serum non-specific alkaline phosphatase by the preliminary incubation of serum in glycine-NaOH buffer containing ethylenediamine tetraacetate and magnesium.	Glycine	164-171	5'-nucleotidase ecto	Homo sapiens	18-33
6714648-3	1984	Chemical analyses of this PTTH have shown that it is a single-chain peptide consisting of 40-43 amino acid residues (MW, 4330-4740), the N-terminus of which is glycine.	Glycine	160-167	prothoracicotropic hormone	Bombyx mori	26-30
3002452-7	1985	In contrast, CF mucin contained a lower content of aspartate, glutamate, and glycine than that observed for the asthmatic mucin.	Glycine	77-84	LOC100508689	Homo sapiens	16-21
6336599-0	1983	Nonketotic hyperglycinemia: two patients with primary defects of P-protein and T-protein, respectively, in the glycine cleavage system.	Glycine	16-23	OCA2 melanosomal transmembrane protein	Homo sapiens	65-74
6336599-3	1983	In one patient, the disturbance of the glycine cleavage system was due to absence of activity of the P-protein.	Glycine	39-46	OCA2 melanosomal transmembrane protein	Homo sapiens	101-110
6626500-3	1983	The Michaelis-Menten parameters for the hydrolysis of the Arg-Gly bond in F-8 by thrombin were determined to be Kcat = 31 X 10(-11) M [(NIH unit/L) s]-1 and KM = 310 X 10(-6) M. Comparison of these values with those determined previously for native fibrinogen and for a series of similar synthetic peptides, together with information about the amino acid sequences of this portion of the A alpha chain of abnormal fibrinogens, suggests an important role for Asp at position P10.	Glycine	62-65	coagulation factor VIII	Homo sapiens	74-77
117939-1	1979	From crude extracts of a Streptomyces strain exhibiting immunopotentiating effects, a tetrapeptide was isolated and its structure established as L Ala leads to D isoGlu leads to L, L Dap comes from Gly.	Glycine	198-201	death associated protein	Homo sapiens	183-186
3908623-7	1985	Immunocytochemistry, using well characterized antisera to alpha-neoendorphin and met-enkephalin-Arg-Gly-Leu, demonstrated that the prodynorphin and proenkephalin products were present in the same cells in the medulla region of the gland.	Glycine	100-103	proenkephalin-A	Cavia porcellus	148-161
953030-3	1976	Polyacrylamide gel electrophoresis in Tris/glycine buffer (pH 8.3) revealed five forms of acetylcholinesterase (acetylcholine hydrolase, EC 3.1.1.7) in the 100 000 X g, 1-h supernatants of aqueous fly-head extracts from the DDT/S strain.	Glycine	43-50	Acetylcholine esterase	Drosophila melanogaster	90-110
71038-2	1976	Insulin stimulates the incorporation of lysine from the 29th day and of glycine from the 31st day of gestation onwards.	Glycine	72-79	insulin	Oryctolagus cuniculus	0-7
14854010-0	1951	Effect of parenterally administered glycine upon action of insulin in rabbits.	Glycine	36-43	insulin	Oryctolagus cuniculus	59-66
33846771-7	2021	A novel co-segregating heterozygous missense variant (c.857A>G; p.Tyr286Cys) in the glycine-tyrosine-glycine signature sequence in the pore region of the KCNQ4 channel was identified.	Glycine	84-91	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	154-159
33846771-7	2021	A novel co-segregating heterozygous missense variant (c.857A>G; p.Tyr286Cys) in the glycine-tyrosine-glycine signature sequence in the pore region of the KCNQ4 channel was identified.	Glycine	101-108	potassium voltage-gated channel subfamily Q member 4	Homo sapiens	154-159
33583954-2	2021	The results of molecular docking positioned four molecules at the interaction site Tyr-491(Spike)-Glu-37(ACE2) and one at the site Gly-488(Spike)-Lys-353(ACE2).	Glycine	131-134	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	139-144
34026780-6	2021	Recently, an amino acid aspartate (D) to glycine (G) (D614G) mutation due to an adenine to guanine nucleotide change at position 23,403 at the 614th amino-acid position of the spike protein in the original reference genotype has been identified.	Glycine	41-48	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	176-181
33939273-6	2021	As the results, the urinary glycine level was higher in the IgAN group than the control groups.	Glycine	28-35	IGAN1	Homo sapiens	60-64
33939273-7	2021	A higher urinary glycine level was associated with lower risk of eGFR 30% decline in IgAN patients.	Glycine	17-24	IGAN1	Homo sapiens	85-89
33939273-8	2021	The addition of glycine to a predictive model including clinicopathologic information significantly improved the predictive power for the prognosis of IgAN [cNRI 0.72 (0.28-0.82)].	Glycine	16-23	IGAN1	Homo sapiens	151-155
33939273-10	2021	Our study demonstrates that urinary glycine may have diagnostic and prognostic value for IgAN and indicates that urinary glycine is a protective biomarker for IgAN.	Glycine	36-43	IGAN1	Homo sapiens	89-93
33939273-10	2021	Our study demonstrates that urinary glycine may have diagnostic and prognostic value for IgAN and indicates that urinary glycine is a protective biomarker for IgAN.	Glycine	121-128	IGAN1	Homo sapiens	159-163
33905418-5	2021	The Mg2+-free MgtE TM domain structure and its comparison with the Mg2+-bound, closed-state structure, together with functional analyses, showed the Mg2+-dependent pore opening of MgtE on the cytoplasmic side and revealed the kink motions of the TM2 and TM5 helices at the glycine residues, which are important for channel activity.	Glycine	273-280	solute carrier family 41 member 1	Homo sapiens	14-18
33905418-5	2021	The Mg2+-free MgtE TM domain structure and its comparison with the Mg2+-bound, closed-state structure, together with functional analyses, showed the Mg2+-dependent pore opening of MgtE on the cytoplasmic side and revealed the kink motions of the TM2 and TM5 helices at the glycine residues, which are important for channel activity.	Glycine	273-280	solute carrier family 41 member 1	Homo sapiens	180-184
33894004-2	2021	Messenger RNAs encoding CAPS1 are subject to a site-specific adenosine-to-inosine (A-to-I) editing event resulting in a glutamate-to-glycine (E-to-G) substitution in the C-terminal domain of the encoded protein product.	Glycine	133-140	Ca2+-dependent secretion activator	Mus musculus	24-29
33428810-3	2021	Here, we report that SLC6A20A, an amino acid transporter known to transport proline based on in vitro data but is understudied in the brain, regulates proline and glycine levels and NMDAR function in the mouse brain.	Glycine	163-170	solute carrier family 6 (neurotransmitter transporter), member 20A	Mus musculus	21-29
33428810-7	2021	Conversely, mice lacking SLC6A20A displayed increased extracellular glycine levels and NMDAR currents.	Glycine	68-75	solute carrier family 6 (neurotransmitter transporter), member 20A	Mus musculus	25-33
33487163-5	2021	We also provide evidence that the S. cerevisiae lipoyl transferase Lip3, in addition to transferring LA from the glycine cleavage system H protein to the pyruvate dehydrogenase (PDH) and alpha-ketoglutarate dehydrogenase (KGD) E2 subunits, can transfer this cofactor from the PDH complex to the KGD complex.	Glycine	113-120	putative lipoate--protein ligase	Saccharomyces cerevisiae S288C	67-71
33569080-1	2021	Glycine cleavage system H protein (GCSH) is a component of the glycine cleavage system (GCS), a conserved protein complex that acts to decarboxylate glycine.	Glycine	63-70	glycine cleavage system protein H (aminomethyl carrier)	Mus musculus	0-33
33569080-1	2021	Glycine cleavage system H protein (GCSH) is a component of the glycine cleavage system (GCS), a conserved protein complex that acts to decarboxylate glycine.	Glycine	63-70	glycine cleavage system protein H (aminomethyl carrier)	Mus musculus	35-39
33569080-1	2021	Glycine cleavage system H protein (GCSH) is a component of the glycine cleavage system (GCS), a conserved protein complex that acts to decarboxylate glycine.	Glycine	149-156	glycine cleavage system protein H (aminomethyl carrier)	Mus musculus	0-33
33569080-1	2021	Glycine cleavage system H protein (GCSH) is a component of the glycine cleavage system (GCS), a conserved protein complex that acts to decarboxylate glycine.	Glycine	149-156	glycine cleavage system protein H (aminomethyl carrier)	Mus musculus	35-39
33569080-10	2021	These findings suggest that GCSH has additional roles beyond function in the glycine cleavage system.	Glycine	77-84	glycine cleavage system protein H (aminomethyl carrier)	Mus musculus	28-32
33446657-3	2021	Here we show that inhibition of PHGDH, the first step in the SSP, cooperates with serine and glycine depletion to inhibit one-carbon metabolism and cancer growth.	Glycine	93-100	3-phosphoglycerate dehydrogenase	Mus musculus	32-37
33506114-5	2021	The second and the dominant variant, represented by 62%, showed aspartate a coil amino acid substitution to glycine an extracellular amino acid at D614G located in the spike recognition binding site.	Glycine	108-115	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	168-173
33408644-5	2020	Glycine acts on one-cell and cleavage-stage mouse embryos through the glycine-gated chloride channel, GLRA4, and uptake via the glycine neurotransmitter transporter, GLYT1.	Glycine	0-7	glycine receptor, alpha 4 subunit	Mus musculus	102-107
32686895-7	2020	Using a combination of molecular docking and biochemical assays, we found that Gln 116 , Phe 119 and Gly 120 of LC3-PE are required for the cleavage by both RavZ and ATG4B, while Glu 117 (LC3) is specific for the cleavage by RavZ.	Glycine	101-104	autophagy related 4B cysteine peptidase	Homo sapiens	166-171
32712279-4	2020	GlyT2 is markedly expressed in brainstem, spinal cord and cerebellum, where it is responsible for glycine uptake into glycinergic and GABAergic terminals.	Glycine	98-105	solute carrier family 6 member 5	Homo sapiens	0-5
33122756-3	2020	We found that the S688Y mutation significantly increases the EC50 of both glycine and D-serine in GluN1/GluN2A and GluN1/GluN2B receptors, and significantly slows desensitisation of GluN1/GluN3A receptors.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	121-127
33114509-6	2020	One statistically significant single nucleotide polymorphism (SNP), rs55941146, which encodes a missense alteration (Val > Gly) in the APBA3 gene, was identified with OR values for association with POF of 13.33 and 4.628 in the discovery and replication sets, respectively.	Glycine	123-126	amyloid beta precursor protein binding family A member 3	Homo sapiens	135-140
32948689-5	2020	GRIP1 is recruited into synapses during LTP, and deletion of Grip1 in neurons blocks synaptic AMPAR accumulation induced by glycine-mediated depolarization.	Glycine	124-131	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	94-99
33023086-0	2020	Transcriptional Activation of Chac1 and Other Atf4-Target Genes Induced by Extracellular l-Serine Depletion is negated with Glycine Consumption in Hepa1-6 Hepatocarcinoma Cells.	Glycine	124-131	ChaC, cation transport regulator 1	Mus musculus	30-35
32654295-6	2020	In addition, silkworms after FIBH gene knock-out or silk gland extirpation showed markedly decreased BmGT1-L transcripts in the midgut and disturbed glycine-serine biosynthesis as silk yield decreased.	Glycine	149-156	fibroin heavy chain	Bombyx mori	29-33
32206789-6	2020	Metabolite profiling analysis revealed that the levels of glycine and serine were increased in the ppc2 leaves, while the abundance of photosynthetic metabolites was decreased under these conditions.	Glycine	58-65	phosphoenolpyruvate carboxylase 2	Arabidopsis thaliana	99-103
32206789-7	2020	The transcript levels of encoding enzymes involved in glycine or serine metabolism was decreased in ppc2 in an ABI5-dependent manner.	Glycine	54-61	phosphoenolpyruvate carboxylase 2	Arabidopsis thaliana	100-104
32295908-5	2020	Here, we identify three mutations (3mut), Met302, Leu320, and Pro329, that stabilize the apex of the Env trimer in a prefusion-closed conformation and show antigenically, structurally, and immunogenically that combining 3mut with other approaches (e.g., repair and stabilize and glycine-helix breaking) yields well-behaved clade C-Env trimers capable of boosting the breadth of FP-directed responses.	Glycine	279-286	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	89-93
32546967-0	2020	Glycine Improves Ischemic Stroke Through miR-19a-3p/AMPK/GSK-3beta/HO-1 Pathway.	Glycine	0-7	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	52-56
32546967-0	2020	Glycine Improves Ischemic Stroke Through miR-19a-3p/AMPK/GSK-3beta/HO-1 Pathway.	Glycine	0-7	glycogen synthase kinase 3 alpha	Homo sapiens	57-66
32546967-14	2020	Rescue experiments demonstrated that glycine improved cell apoptosis, inflammatory response and glucose metabolism disorder of ischemic stroke through miR-19a-3p/AMPK/GSK-3beta/HO-1 pathway.	Glycine	37-44	glycogen synthase kinase 3 alpha	Homo sapiens	167-176
32546967-15	2020	Conclusion: Glycine improves ischemic stroke through miR-19a-3p/AMPK/GSK-3beta/HO-1 pathway.	Glycine	12-19	glycogen synthase kinase 3 alpha	Homo sapiens	69-78
32209436-4	2020	Glycine boosts satellite cell proliferation and muscle regeneration by increasing activation of mammalian target of rapamycin complex 1 (mTORC1) and replenishing the one-carbon unit pool.	Glycine	0-7	CREB regulated transcription coactivator 1	Mus musculus	137-143
31693171-5	2020	Key Results CBD activity is partially dependent upon the mitochondrial glycine cleavage system component, GcvH1 in Dictyostelium, orthologous to the human GCSH protein, which is functionally linked to folate one-carbon metabolism (FOCM).	Glycine	71-78	glycine cleavage system protein H	Homo sapiens	155-159
32064161-0	2020	PLCepsilon knockdown prevents serine/glycine metabolism and proliferation of prostate cancer by suppressing YAP.	Glycine	37-44	phospholipase C like 1 (inactive)	Homo sapiens	0-10
32064161-7	2020	Secondly, PLCepsilon knockdown can inhibit serine/glycine producing and proliferation of PCa both in vivo and in vitro.	Glycine	50-57	phospholipase C like 1 (inactive)	Homo sapiens	10-20
32064161-8	2020	Mechanistically, PLCepsilon may affect the serine/glycine metabolism by regulating dephosphorylation and nuclear translocation of YAP.	Glycine	50-57	phospholipase C like 1 (inactive)	Homo sapiens	17-27
32064161-9	2020	More interestingly, verteporfin (VP, a specific inhibitor of YAP) could effectively enhance the PLCepsilon-depletion induced inhibition of serine/glycine secretion and growth.	Glycine	146-153	phospholipase C like 1 (inactive)	Homo sapiens	96-106
32064161-10	2020	Overall, this research revealed the possibility of anomalous serine/glycine levels in the blood for the diagnosis of PCa, identified the important role of the PLCepsilon/YAP axis in regulating serine/glycine metabolism, cell proliferation and tumor growth, and suggested the combination of VP with PLCepsilon-depletion may provide a new idea for the treatment of PCa.	Glycine	200-207	phospholipase C like 1 (inactive)	Homo sapiens	159-169
32064161-10	2020	Overall, this research revealed the possibility of anomalous serine/glycine levels in the blood for the diagnosis of PCa, identified the important role of the PLCepsilon/YAP axis in regulating serine/glycine metabolism, cell proliferation and tumor growth, and suggested the combination of VP with PLCepsilon-depletion may provide a new idea for the treatment of PCa.	Glycine	200-207	Yes1 associated transcriptional regulator	Homo sapiens	170-173
31260673-5	2020	CENPV, a constituent of mitotic chromosomes associating with cytoplasmic microtubules, interacts with CYLD through the region between the third cytoskeleton-associated protein-glycine domain and the active site.	Glycine	176-183	centromere protein V	Homo sapiens	0-5
30660387-1	2019	Non-syndromic microcytic congenital sideroblastic anemia (cSA) is predominantly caused by defective genes encoding for either ALAS2, the first enzyme of heme biosynthesis pathway or SLC25A38, the mitochondrial importer of glycine, an ALAS2 substrate.	Glycine	222-229	solute carrier family 25 member 38	Homo sapiens	182-190
30737140-11	2019	Decreased ALAS2 activity results either directly from loss-of-function ALAS2 mutations as seen in X-linked sideroblastic anemia (XLSA) or from defect in the availability of one of its two mitochondrial substrates: glycine in SLC25A38 mutations and succinyl CoA in GLRX5 mutations.	Glycine	214-221	5'-aminolevulinate synthase 2	Homo sapiens	10-15
30737140-11	2019	Decreased ALAS2 activity results either directly from loss-of-function ALAS2 mutations as seen in X-linked sideroblastic anemia (XLSA) or from defect in the availability of one of its two mitochondrial substrates: glycine in SLC25A38 mutations and succinyl CoA in GLRX5 mutations.	Glycine	214-221	solute carrier family 25 member 38	Homo sapiens	225-233
31717805-6	2019	Integrated omics revealed that biological pathways related to amino acid metabolism, particularly alanine and glycine metabolism, were affected in the liver by disruption of Scly in mice with selenium adequacy.	Glycine	110-117	selenocysteine lyase	Mus musculus	174-178
31717805-7	2019	We further confirmed that hepatic glycine levels are elevated in male, but not in female, Scly KO mice.	Glycine	34-41	selenocysteine lyase	Mus musculus	90-94
31279534-2	2019	We identified two carriers (mother and son) of a triplication of the gene encoding glycine decarboxylase, GLDC, presumably resulting in reduced availability of the N-methyl-D-aspartate receptor coagonists glycine and D-serine and N-methyl-D-aspartate receptor hypofunction.	Glycine	83-90	glycine decarboxylase	Homo sapiens	106-110
31302238-7	2019	This pathological overactivation of NR1/NR2B receptors can be reduced by GlyT-1 inhibitors (NFPS, Org-25935), which decrease excessive glycine release from astroglial cells or by selective antagonists of NR2B subunits (ifenprodil, Ro 25-6981).	Glycine	135-142	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	40-44
30448461-6	2019	Of these, the arginine/glycine site of SON mRNA was newly identified as an ADAR2-dependent site.	Glycine	23-30	adenosine deaminase RNA specific B1	Homo sapiens	75-80
31375578-4	2019	Both in vitro and in vivo studies indicated that direct interaction of p17 with hnRNA1 maps within the amino terminus (aa 19-40) of p17 and the Gly-rich region of the C terminus of hnRNP A1.	Glycine	144-147	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	181-189
31104335-8	2019	Follow-up analyses suggested that glycine mediates the relationship between carbamoyl-phosphate synthase 1 and measures of cardiovascular and diabetes risk, including body mass index, waist-hip ratio, inflammation, and insulin resistance.	Glycine	34-41	carbamoyl-phosphate synthase 1	Homo sapiens	76-106
31444392-4	2019	We found that the structural features of the glycine-binding sites in both GluN1 and GluN3A subunits are correlated with receptor forward trafficking to the cell surface.	Glycine	45-52	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	75-80
31444392-4	2019	We found that the structural features of the glycine-binding sites in both GluN1 and GluN3A subunits are correlated with receptor forward trafficking to the cell surface.	Glycine	45-52	glutamate ionotropic receptor NMDA type subunit 3A	Rattus norvegicus	85-91
30947017-0	2019	Protective effect of glycine in streptozotocin-induced diabetic cataract through aldose reductase inhibitory activity.	Glycine	21-28	aldo-keto reductase family 1 member B1	Rattus norvegicus	81-97
30947017-8	2019	Glycine treatment increased body weight gain, reduced blood glucose, and increased plasma insulin levels compared to diabetic control rats, and also increased GSH content and decreased mRNA and protein levels of aldose reductase compared to their respective controls.	Glycine	0-7	aldo-keto reductase family 1 member B1	Rattus norvegicus	212-228
30947017-9	2019	In summary, glycine supplementation effectively inhibited aldose reductase enzyme activity in experimental diabetic rats.	Glycine	12-19	aldo-keto reductase family 1 member B1	Rattus norvegicus	58-74
29737046-4	2019	The RCP used here is based on the alpha-1 sequence of human collagen type I and contains 12 Arg-Gly-Asp motifs.	Glycine	96-99	CGRP receptor component	Homo sapiens	4-7
31113850-0	2019	mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-beta1-induced collagen biosynthesis.	Glycine	51-58	CREB regulated transcription coactivator 1	Mus musculus	0-6
30769008-4	2019	Mutation of the PKA-phosphorylation site (substitution of three serines by alanine or glycine) resulted in a further increase in cell motility compared to wild-type Cx43, but with a loss of directionality.	Glycine	86-93	gap junction protein alpha 1	Homo sapiens	165-169
30778749-4	2019	METHODS: The Homo MICA extracellular domains (hMICA) were fused to the end of the heavy chain of cG7 with the flexible pentapeptide (Gly-Gly-Gly-Gly-Ser; G4S), which formed the cG7-MICA that was further identified using sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and western blotting (WB).	Glycine	133-136	MHC class I polypeptide-related sequence A	Homo sapiens	47-51
6834065-4	1983	Monensin at 0.10 microM markedly decreased the appearance of [14C]glycine-labeled PLP in myelin, but had little effect on the 14C basic proteins or the incorporation of [3H]palmitic acid into total or myelin PLP.	Glycine	66-73	proteolipid protein 1	Rattus norvegicus	82-85
6830816-9	1983	For each of the elastin samples analyzed, approximately one residue of glycine was recovered per 800 total residues.	Glycine	71-78	elastin	Coturnix japonica	16-23
7107590-8	1982	A linear increase in radioactivity from [3H]palmitic acid was observed in PLP in both myelin and myelin-like fractions, while appearance of [14C]glycine-labeled PLP showed a lag of 45-60 minutes.	Glycine	145-152	proteolipid protein 1	Rattus norvegicus	161-164
6788045-4	1981	The precipitate is dissolved in a saccharose/glycine solution and heated at 60 degrees C for 10 h. The factor VIII is then separated by further precipitation with sodium chloride, the precipitate dissolved, dialysed and sterilized by filtration.	Glycine	45-52	cytochrome c oxidase subunit 8A	Homo sapiens	110-114
6778858-3	1980	In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM.	Glycine	51-58	myosin binding protein H	Rattus norvegicus	122-131
6778858-3	1980	In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM.	Glycine	51-58	myosin binding protein H	Rattus norvegicus	195-204
6778858-3	1980	In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM.	Glycine	164-171	myosin binding protein H	Rattus norvegicus	122-131
894028-4	1977	Nonresponder inbred strain 2 guinea pigs were able to produce anti(T-G-A-Gly)n antibodies when immunized with (T-G-A-Gly)n and methylated bovine serum albumin (MBSA) complex, although there was no delayed skin reaction and in vitro cultured lymphocytes did not respond.	Glycine	73-76	albumin	Cavia porcellus	145-158
17398-6	1977	When the amino acid content of the enzymes was analysed, carboxypeptidase B2 had four more glycine and three more aspartic acid residues than had form B1.	Glycine	91-98	carboxypeptidase B2	Homo sapiens	57-76
833149-1	1977	A 63-residue RNase A analog containing residues 26 to 35 then alanine, 41 to 59 and 73 to 84 then glycine, 100 to 110 then glycine, and 117 to 124 was synthesized by the solid phase method.	Glycine	98-105	ribonuclease A family member 1, pancreatic	Homo sapiens	13-20
833149-1	1977	A 63-residue RNase A analog containing residues 26 to 35 then alanine, 41 to 59 and 73 to 84 then glycine, 100 to 110 then glycine, and 117 to 124 was synthesized by the solid phase method.	Glycine	123-130	ribonuclease A family member 1, pancreatic	Homo sapiens	13-20
986943-7	1976	It has been found that by extending the aminoacyl group of N-acetyl-L-lysine methyl ester by one glycine residue (n = 1), a greatly enhanced deacylation rate constant is observed for both alpha and beta-trypsin.	Glycine	97-104	serine protease 1	Bos taurus	198-210
1176817-4	1975	Elution of Hb-A2 with a glycine-KCN developer is much less sensitive to minor change in pH of the developer, but is greatly dependent on the pH of the ion exchanger.	Glycine	24-31	hemoglobin subunit alpha 2	Homo sapiens	11-16
1141204-15	1975	Intracellular concentrations of seven amino acids, including threonine, serine, proline, glycine, alanine, lysine, and arginine, were increased significantly in livers perfused with medium containing growth hormone...	Glycine	89-96	gonadotropin releasing hormone receptor	Rattus norvegicus	200-214
4329715-11	1971	When grown in such supplemented media, the mutant lacks serine hydroxymethyltransferase and revertants to wild-type phenotype regained enzymic activity showing that during growth on succinate, lactate or ethanol, glycine is made from serine via serine hydroxymethyltransferase, and that the organism can obtain C(1) units from glycine.	Glycine	213-220	glyA	Methylobacterium extorquens AM1	56-87
4329715-11	1971	When grown in such supplemented media, the mutant lacks serine hydroxymethyltransferase and revertants to wild-type phenotype regained enzymic activity showing that during growth on succinate, lactate or ethanol, glycine is made from serine via serine hydroxymethyltransferase, and that the organism can obtain C(1) units from glycine.	Glycine	213-220	glyA	Methylobacterium extorquens AM1	245-276
5983970-0	1966	[Changes in the incorporation of glycine-2C14 and Ca45 into calcified tissues after repeated administration of P32 to the organism].	Glycine	33-40	inhibitor of growth family member 2	Homo sapiens	111-114
33969941-4	2021	Our study reveals that the conformational stabilization of alphaC-helix near the allosteric binding site, including conformational changes in activation and glycine-rich loop regions, favors the specificity of WNK476 towards WNK1.	Glycine	157-164	WNK lysine deficient protein kinase 1	Homo sapiens	225-229
33249721-0	2021	The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase.	Glycine	53-60	serine racemase	Homo sapiens	100-115
33866786-4	2021	Herein, we developed a novel CL probe for the detection of endogenous FAPalpha activity by incorporating FAPalpha-specific dipeptide substrates (glycine-proline) to the improved Schaap"s adamantylidene-dioxetane.	Glycine	145-152	fibroblast activation protein	Mus musculus	70-78
33866786-4	2021	Herein, we developed a novel CL probe for the detection of endogenous FAPalpha activity by incorporating FAPalpha-specific dipeptide substrates (glycine-proline) to the improved Schaap"s adamantylidene-dioxetane.	Glycine	145-152	fibroblast activation protein	Mus musculus	105-113
33836787-13	2021	CONCLUSIONS: We have identified an association of a specific glycine at position 10 of Gag-SP1 with an MI susceptible phenotype of HIV-1 subtype C viruses.	Glycine	61-68	Pr55(Gag)	Human immunodeficiency virus 1	87-90
33867731-0	2021	Evaluation of LKB1 and Serine-Glycine Metabolism Pathway Genes (SHMT1 and GLDC) Expression in AML.	Glycine	30-37	glycine decarboxylase	Homo sapiens	74-78
33934471-7	2021	AIMS: The aim of our study was to evaluate the potential inhibition of ODC1 activity by a cream containing 4% capryloyl glycine, an ODC1 inhibitor, and 1% glycine soy-fermented extract (soy isoflavonoids).	Glycine	120-127	ornithine decarboxylase 1	Homo sapiens	71-75
33688625-3	2021	Using CRISPR-Cas9, our lab generated a C. elegans model for Saul-Wilson Syndrome by recreating the same glycine-to-arginine substitution in the worm ortholog cogc-4.	Glycine	104-111	Conserved oligomeric Golgi complex subunit 4	Caenorhabditis elegans	158-164
34046625-6	2021	According to the molecular docking analysis, compounds 11, 12 and 25 formed hydrogen bonds with the hinge region residues Lys857, Leu932 and Glu930 and hydrophobically came into contact with Leu983 at the catalytic site of JAK2, while compound 25 formed a hydrogen bond with Met769 at the hinge region, Lys721 near a glycine loop, and Asp831 at the activation loop of EGFR.	Glycine	317-324	Janus kinase 2	Homo sapiens	223-227
32785674-0	2021	RNA-recognition motifs and glycine and arginine-rich region cooperatively regulate the nucleolar localization of nucleolin.	Glycine	27-34	nucleolin	Homo sapiens	113-122
32785674-1	2021	Nucleolin (NCL) is a nucleolar protein that is involved in the regulation of the nucleolar structure and functions, and consists of three distinct regions: the N-terminal region; the middle region, which contains four RNA-recognition motifs (RRMs); and the C-terminal glycine and arginine-rich (GAR) region.	Glycine	268-275	nucleolin	Homo sapiens	0-9
32785674-1	2021	Nucleolin (NCL) is a nucleolar protein that is involved in the regulation of the nucleolar structure and functions, and consists of three distinct regions: the N-terminal region; the middle region, which contains four RNA-recognition motifs (RRMs); and the C-terminal glycine and arginine-rich (GAR) region.	Glycine	268-275	nucleolin	Homo sapiens	11-14
33553759-5	2021	Meanwhile, voltage-dependent inactivation was reduced in TRPM5 mutants having glycine substitution at L901, Y913, Q915 and I916 in the pore helix.	Glycine	78-85	transient receptor potential cation channel subfamily M member 5	Homo sapiens	57-62
33523018-5	2021	METHODS: In the present study, the protease resistant Gly(2)-GLP-2 (50 nmol/kg ip.)	Glycine	54-57	glucagon-like peptide 2 receptor	Mus musculus	61-66
33523018-9	2021	Gly(2)-GLP-2 treatment also protected dopaminergic neurons and restored tyrosine hydroxylase expression levels in the substantia nigra.	Glycine	0-3	glucagon-like peptide 2 receptor	Mus musculus	7-12
33523018-10	2021	Gly(2)-GLP-2 furthermore reduced the inflammation response as seen in lower microglia activation, and decreased NLRP3 and interleukin-1beta pro-inflammatory cytokine expression levels.	Glycine	0-3	glucagon-like peptide 2 receptor	Mus musculus	7-12
33266291-4	2020	Serine hydroxymethyltransferase (SHMT) is indispensable for the one-carbon metabolism of serine/glycine interconversion and is linked to folate metabolism.	Glycine	96-103	AT695_RS06945	Staphylococcus aureus	0-31
33266291-4	2020	Serine hydroxymethyltransferase (SHMT) is indispensable for the one-carbon metabolism of serine/glycine interconversion and is linked to folate metabolism.	Glycine	96-103	AT695_RS06945	Staphylococcus aureus	33-37
33176135-0	2020	Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.	Glycine	76-83	AT-rich interaction domain 4B	Rattus norvegicus	28-32
33176135-2	2020	Metabolites and genes related to BCAA metabolism and nitrogen handling were strongly associated with glycine in correlation analyses.	Glycine	101-108	AT-rich interaction domain 4B	Rattus norvegicus	33-37
33176135-3	2020	Stable isotope labeling in Zucker fatty rats (ZFRs) shows that glycine acts as a carbon donor for the pyruvate-alanine cycle in a BCAA-regulated manner.	Glycine	63-70	AT-rich interaction domain 4B	Rattus norvegicus	130-134
32668192-3	2020	TGF-beta upregulates the expression of the enzymes of the de novo serine-glycine synthesis pathway in lung fibroblasts; however, the transcriptional and signaling regulators of this pathway remain incompletely understood.	Glycine	73-80	transforming growth factor alpha	Homo sapiens	0-8
32668192-4	2020	Here, we demonstrate that TGF-beta promotes accumulation of ATF4 (activating transcription factor 4), which is required for increased expression of the serine-glycine synthesis pathway enzymes in response to TGF-beta.	Glycine	159-166	transforming growth factor alpha	Homo sapiens	26-34
32668192-4	2020	Here, we demonstrate that TGF-beta promotes accumulation of ATF4 (activating transcription factor 4), which is required for increased expression of the serine-glycine synthesis pathway enzymes in response to TGF-beta.	Glycine	159-166	transforming growth factor alpha	Homo sapiens	208-216
32804429-1	2020	Glutaric acidemia type 2 (GA2), also called multiple acyl-CoA dehydrogenase deficiency, is an autosomal recessive disorder of fatty acid, amino acid, and choline metabolism resulting in excretion of multiple organic acids and glycine conjugates as well as elevation of various plasma acylcarnitine species (C4-C18).	Glycine	226-233	electron transfer flavoprotein subunit alpha	Homo sapiens	0-24
32804429-1	2020	Glutaric acidemia type 2 (GA2), also called multiple acyl-CoA dehydrogenase deficiency, is an autosomal recessive disorder of fatty acid, amino acid, and choline metabolism resulting in excretion of multiple organic acids and glycine conjugates as well as elevation of various plasma acylcarnitine species (C4-C18).	Glycine	226-233	electron transfer flavoprotein subunit alpha	Homo sapiens	26-29
32712301-2	2020	The extracellular glycine concentration is regulated synergistically by two high affinity, large capacity transporters GlyT1 and GlyT2.	Glycine	18-25	solute carrier family 6 member 5	Homo sapiens	129-134
32579955-0	2020	Analgesic action of adenosine A1 receptor involves the dephosphorylation of glycine receptor alpha1ins subunit in spinal dorsal horn of mice.	Glycine	76-83	adenosine A1 receptor	Mus musculus	30-41
32436225-3	2020	Previous studies have shown that glycine receptors (GlyRs) present in the nAc are potentiated by clinically-relevant concentrations of ethanol, where alpha1 and alpha2 are the predominant subunits expressed.	Glycine	33-40	G protein-coupled receptor 162	Mus musculus	161-167
32859182-13	2020	Mechanistic studies found that the anti-inflammatory activity of GLY was related to the inhibition of pro-inflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and PGE2 and that GLY reduced the expression of COX-2 and NF-kappaB p65 proteins in the throat, attenuated throat injury, and reduced inflammatory exudates.	Glycine	65-68	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	212-217
32859182-13	2020	Mechanistic studies found that the anti-inflammatory activity of GLY was related to the inhibition of pro-inflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and PGE2 and that GLY reduced the expression of COX-2 and NF-kappaB p65 proteins in the throat, attenuated throat injury, and reduced inflammatory exudates.	Glycine	182-185	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	212-217
32859182-15	2020	CONCLUSIONS: These studies indicated that GLY has beneficial anti-inflammatory effects on CP and that it acts through reducing pro-inflammatory factors such as IL-1beta, IL-6, TNF-alpha, and PGE2, as well as decreasing WBC, NEUT, LYMPH and MONO levels and decreasing the expression of COX-2 and NF-kappaB p65 proteins.	Glycine	42-45	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	285-290
32833997-10	2020	In contrast, Cryab-R120G knock-in lenses exhibited increased total amino acid content including valine, alanine, serine, leucine, isoleucine, glycine, and aspartic acid.	Glycine	142-149	crystallin, alpha B	Mus musculus	13-18
32374903-2	2020	The major mutation detected to date in the SARS-CoV-2 viral envelope spike protein, which is responsible for virus attachment to the host and is also the main target for host antibodies, is a mutation of an aspartate (D) at position 614 found frequently in Chinese strains to a glycine (G).	Glycine	278-285	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	69-74
32699277-3	2020	A previous study found variants in genes associated with glycine-serine metabolism (PSPH, PHGDH and CPS1) to be associated with MacTel, and showed low levels of glycine and serine in the serum of MacTel patients.	Glycine	57-64	phosphoglycerate dehydrogenase	Homo sapiens	90-95
32699277-3	2020	A previous study found variants in genes associated with glycine-serine metabolism (PSPH, PHGDH and CPS1) to be associated with MacTel, and showed low levels of glycine and serine in the serum of MacTel patients.	Glycine	57-64	carbamoyl-phosphate synthase 1	Homo sapiens	100-104
32699277-3	2020	A previous study found variants in genes associated with glycine-serine metabolism (PSPH, PHGDH and CPS1) to be associated with MacTel, and showed low levels of glycine and serine in the serum of MacTel patients.	Glycine	161-168	carbamoyl-phosphate synthase 1	Homo sapiens	100-104
32423801-8	2020	Furthermore, expressions of vascular endothelial growth factor (VEGF) (an angiogenic factor) and nitric oxide synthase (NOS) (an enzyme for nitric oxide synthesis) were associated with the dose-dependent effects of glycine.	Glycine	215-222	nitric oxide synthase 1 (neuronal)	Danio rerio	97-118
32587973-2	2020	We therefore compared the functional properties of the S proteins with aspartic acid (S D614 ) and glycine (S G614 ) at residue 614.	Glycine	99-106	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	55-56
32350111-7	2020	We demonstrate that unique BMP15 finger residues at this site (Arg-301, Gly-304, His-307, and Met-369) enable potent activation of the SMAD2/3 pathway.	Glycine	72-75	SMAD family member 2	Homo sapiens	135-142
32336957-5	2020	The results revealed that the identified ORF1ab polyprotein belongs to a part of nonstructural protein 1 (nsp1) with the high antigenicity residues in a glycine-proline or hydrophobic amino acid rich domain.	Glycine	153-160	ORF1a polyprotein;ORF1ab polyprotein	Severe acute respiratory syndrome coronavirus 2	41-59
30832369-0	2019	Conserved Glycines Control Disorder and Function in the Cold-Regulated Protein, COR15A.	Glycine	10-18	cold-regulated 15a	Arabidopsis thaliana	80-86
30832369-10	2019	Altogether, our results suggest the conserved glycine residues are important for maintaining the disordered structure of COR15A but are also compatible with the formation of alpha-helical structure during freezing induced dehydration.	Glycine	46-53	cold-regulated 15a	Arabidopsis thaliana	121-127
30483907-7	2019	Western blot analysis showed that 100-200% glycine enhanced the protein levels of occludin, claudin-1, and zonula occludens (ZO)-1 without affecting those of claudin-3, ZO-2, and ZO-3.	Glycine	43-50	occludin	Homo sapiens	82-90
30483907-8	2019	Further studies showed that protein abundances of glucose-regulated protein 78 (BiP/GRP78) and p-IRE1alpha, instead of ATF6alpha, were reduced by glycine.	Glycine	146-153	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	97-106
2866019-4	1985	In this report, we show that 3 neuroactive peptides (enkephalin, neurotensin and somatostatin) are present in subpopulations of amacrine cells which also possess a high affinity uptake system for glycine.	Glycine	196-203	somatostatin 1	Gallus gallus	81-93
30804330-1	2019	Glycine decarboxylase (GLDC) belongs to the glycine cleavage system and is involved in one-carbon metabolism.	Glycine	44-51	glycine decarboxylase	Homo sapiens	0-21
30804330-1	2019	Glycine decarboxylase (GLDC) belongs to the glycine cleavage system and is involved in one-carbon metabolism.	Glycine	44-51	glycine decarboxylase	Homo sapiens	23-27
4084504-0	1985	Clustering of glycine and NG,NG-dimethylarginine in nucleolar protein C23.	Glycine	14-21	nucleolin	Homo sapiens	70-73
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Glycine	12-15	myelin basic protein	Homo sapiens	58-78
30833887-0	2019	Glycine Regulates Neural Stem Cell Proliferation During Development via Lnx1-Dependent Notch Signaling.	Glycine	0-7	ligand of numb-protein X 1	Danio rerio	72-76
30833887-2	2019	We found that glycine signaling suppresses the expression of Ligand of Numb X1 (lnx1, Ligand of numb protein-x1), a gene of unknown function during NSC differentiation that is selectively expressed in the embryonic central nervous system (CNS).	Glycine	14-21	ligand of numb-protein X 1	Danio rerio	61-78
30833887-2	2019	We found that glycine signaling suppresses the expression of Ligand of Numb X1 (lnx1, Ligand of numb protein-x1), a gene of unknown function during NSC differentiation that is selectively expressed in the embryonic central nervous system (CNS).	Glycine	14-21	ligand of numb-protein X 1	Danio rerio	80-84
30833887-2	2019	We found that glycine signaling suppresses the expression of Ligand of Numb X1 (lnx1, Ligand of numb protein-x1), a gene of unknown function during NSC differentiation that is selectively expressed in the embryonic central nervous system (CNS).	Glycine	14-21	ligand of numb-protein X 1	Danio rerio	86-111
30833887-6	2019	Thus, our data provide evidence that glycine/lnx1 signaling modulates NSC proliferation by regulation of Notch signaling.	Glycine	37-44	ligand of numb-protein X 1	Danio rerio	45-49
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Glycine	12-15	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Glycine	12-15	myelin basic protein	Homo sapiens	142-145
6095120-5	1984	This apparently unique gene organization suggests that yeast ubiquitin is generated by processing of a precursor protein in which several exact repeats of the ubiquitin amino acid sequence are joined directly via Gly-Met peptide bonds between the last and first residues of mature ubiquitin, respectively.	Glycine	213-216	ubiquitin	Saccharomyces cerevisiae S288C	61-70
32124747-6	2019	The increased risk of influenza development is associated with the Asp/Gly genotype of TLR-4 (OR=4.22) and combination of mutant genotypes Leu/Phe and Phe/Phe of TLR-3 with Asp/Gly of TLR-4 and Arg/Gln of TLR-2 (OR=15.0); influenza-associated pneumonia - with genotype Phe/Phe of TLR-3 (OR=4.5).	Glycine	177-180	toll like receptor 3	Homo sapiens	162-167
30627284-2	2018	Multiple polymorphisms of the ADRB1 have been identified such as the Gly49 polymorphism that includes at least one glycine (Gly) for serine (Ser) at amino acid 49 resulting in either homozygous for Gly (Gly49Gly) or heterozygous for Gly (Gly49Ser) polymorphisms.	Glycine	115-122	adrenoceptor beta 1	Homo sapiens	30-35
6095120-5	1984	This apparently unique gene organization suggests that yeast ubiquitin is generated by processing of a precursor protein in which several exact repeats of the ubiquitin amino acid sequence are joined directly via Gly-Met peptide bonds between the last and first residues of mature ubiquitin, respectively.	Glycine	213-216	ubiquitin	Saccharomyces cerevisiae S288C	159-168
6095120-5	1984	This apparently unique gene organization suggests that yeast ubiquitin is generated by processing of a precursor protein in which several exact repeats of the ubiquitin amino acid sequence are joined directly via Gly-Met peptide bonds between the last and first residues of mature ubiquitin, respectively.	Glycine	213-216	ubiquitin	Saccharomyces cerevisiae S288C	159-168
6372790-2	1984	The present study indicated the following: (a) Increases of 80 and 50% in plasma glycine disappearance rate constants occurred in insulin- and glucagon-treated rabbits as compared with control postabsorptive rabbits; (b) The hormones in the intact rabbits caused a significant depletion in glycine pool size, which led to a moderate reduction in the fluxes of glycine.	Glycine	81-88	insulin	Oryctolagus cuniculus	130-137
30627284-2	2018	Multiple polymorphisms of the ADRB1 have been identified such as the Gly49 polymorphism that includes at least one glycine (Gly) for serine (Ser) at amino acid 49 resulting in either homozygous for Gly (Gly49Gly) or heterozygous for Gly (Gly49Ser) polymorphisms.	Glycine	69-72	adrenoceptor beta 1	Homo sapiens	30-35
30627284-2	2018	Multiple polymorphisms of the ADRB1 have been identified such as the Gly49 polymorphism that includes at least one glycine (Gly) for serine (Ser) at amino acid 49 resulting in either homozygous for Gly (Gly49Gly) or heterozygous for Gly (Gly49Ser) polymorphisms.	Glycine	124-127	adrenoceptor beta 1	Homo sapiens	30-35
30627284-2	2018	Multiple polymorphisms of the ADRB1 have been identified such as the Gly49 polymorphism that includes at least one glycine (Gly) for serine (Ser) at amino acid 49 resulting in either homozygous for Gly (Gly49Gly) or heterozygous for Gly (Gly49Ser) polymorphisms.	Glycine	124-127	adrenoceptor beta 1	Homo sapiens	30-35
30627284-4	2018	The purpose of this study was to determine the effects of the Gly/Ser polymorphism at position 49 of the ADRB1on the cardiovascular response to exercise in healthy subjects.	Glycine	62-65	adrenoceptor beta 1	Homo sapiens	105-110
6372790-2	1984	The present study indicated the following: (a) Increases of 80 and 50% in plasma glycine disappearance rate constants occurred in insulin- and glucagon-treated rabbits as compared with control postabsorptive rabbits; (b) The hormones in the intact rabbits caused a significant depletion in glycine pool size, which led to a moderate reduction in the fluxes of glycine.	Glycine	290-297	insulin	Oryctolagus cuniculus	130-137
6372790-2	1984	The present study indicated the following: (a) Increases of 80 and 50% in plasma glycine disappearance rate constants occurred in insulin- and glucagon-treated rabbits as compared with control postabsorptive rabbits; (b) The hormones in the intact rabbits caused a significant depletion in glycine pool size, which led to a moderate reduction in the fluxes of glycine.	Glycine	290-297	insulin	Oryctolagus cuniculus	130-137
6372790-4	1984	(d) Sublethal doses of cycloheximide inhibited by 60 and 90% the stimulatory action of insulin and glucagon on plasma glycine disappearance, respectively.	Glycine	118-125	insulin	Oryctolagus cuniculus	87-94
30403859-3	2018	Here, a chlorantraniliprole-glycine conjugate (CAP-Gly-1) was tested for its affinity to AtLHT1 both in planta and in vitro.	Glycine	28-35	lysine histidine transporter 1	Arabidopsis thaliana	89-95
6372790-5	1984	The present data suggest that both insulin and glucagon may act directly on plasma glycine disappearance rates.	Glycine	83-90	insulin	Oryctolagus cuniculus	35-42
30403859-3	2018	Here, a chlorantraniliprole-glycine conjugate (CAP-Gly-1) was tested for its affinity to AtLHT1 both in planta and in vitro.	Glycine	51-54	lysine histidine transporter 1	Arabidopsis thaliana	89-95
6372790-7	1984	Presumably glucagon and insulin modify the glycine transport system at different sites or by a different mechanism.	Glycine	43-50	insulin	Oryctolagus cuniculus	24-31
30403859-4	2018	Seedlings deficient in AtLHT1 exhibited a reduction with respect to both the uptake and root-to-shoot transfer of CAP-Gly-1; plants in which AtLHT1 was constitutively expressed were more effective than wild type in term of their root uptake of CAP-Gly-1.	Glycine	118-121	lysine histidine transporter 1	Arabidopsis thaliana	23-29
30403859-4	2018	Seedlings deficient in AtLHT1 exhibited a reduction with respect to both the uptake and root-to-shoot transfer of CAP-Gly-1; plants in which AtLHT1 was constitutively expressed were more effective than wild type in term of their root uptake of CAP-Gly-1.	Glycine	248-251	lysine histidine transporter 1	Arabidopsis thaliana	23-29
6619114-4	1983	It was demonstrated that an extra peptide of 21 amino acid residues, including 5 leucine, 4 serine, 1 glycine, and 1 methionine residues, is located at the amino terminus of the ATPase inhibitor precursor.	Glycine	102-109	dynein axonemal heavy chain 8	Homo sapiens	178-184
30403859-4	2018	Seedlings deficient in AtLHT1 exhibited a reduction with respect to both the uptake and root-to-shoot transfer of CAP-Gly-1; plants in which AtLHT1 was constitutively expressed were more effective than wild type in term of their root uptake of CAP-Gly-1.	Glycine	248-251	lysine histidine transporter 1	Arabidopsis thaliana	141-147
30403859-5	2018	Protoplast patch clamping showed that the presence in the external medium of CAP-Gly-1 was able to induce AtLHT1 genotype-dependent inward currents.	Glycine	81-84	lysine histidine transporter 1	Arabidopsis thaliana	106-112
6221944-4	1983	In addition, results compatible with a positional Ser/Gly microheterogeneity were obtained at a single position (position L-4 which is equal to S-1).	Glycine	54-57	ribosomal protein L4	Homo sapiens	122-125
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	117-124	OCA2 melanosomal transmembrane protein	Homo sapiens	81-90
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	117-124	OCA2 melanosomal transmembrane protein	Homo sapiens	81-90
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	117-124	OCA2 melanosomal transmembrane protein	Homo sapiens	81-90
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	242-249	OCA2 melanosomal transmembrane protein	Homo sapiens	24-33
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	242-249	OCA2 melanosomal transmembrane protein	Homo sapiens	81-90
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	242-249	OCA2 melanosomal transmembrane protein	Homo sapiens	81-90
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	242-249	OCA2 melanosomal transmembrane protein	Homo sapiens	81-90
6762537-5	1982	Analogs with non-aromatic or hydrophilic amino acids (X: Gly, Leu, Arg, His, Glu) in position 1 generally have much lower activities in this series of LH-RH antagonists.	Glycine	57-60	gonadotropin releasing hormone 1	Homo sapiens	151-156
7050119-9	1982	These studies indicate that the structure of chicken hypothalamic LH-RH is: pGlu-His-Trp-Ser-Tyr-Gly-Leu-Gln-Pro-Gly-NH2.	Glycine	97-100	gonadotropin releasing hormone 1	Homo sapiens	66-71
6126215-1	1982	To investigate the possible role of aminopeptidase N (alpha-aminoacyl-peptide hydrolase (microsomal), EC 3.4.11.2) in the transport of amino acids from oligopeptides, the modified amino acids Phe(N3) and Phe(N3, I) and the tetrapeptides Phe(N3) or Phe(N3, I)-L-or-DAla-Gly-Gly have been synthesized.	Glycine	268-272	alanyl aminopeptidase, membrane	Homo sapiens	36-52
6126215-1	1982	To investigate the possible role of aminopeptidase N (alpha-aminoacyl-peptide hydrolase (microsomal), EC 3.4.11.2) in the transport of amino acids from oligopeptides, the modified amino acids Phe(N3) and Phe(N3, I) and the tetrapeptides Phe(N3) or Phe(N3, I)-L-or-DAla-Gly-Gly have been synthesized.	Glycine	269-272	alanyl aminopeptidase, membrane	Homo sapiens	36-52
6279643-6	1982	The tryptic fragment containing the major phosphorylation site was identified by amino acid composition and sequence as HMG 14 (residues 4-13): H-Lys-Val-Ser(P)-Ser-Ala-Glu-Gly-Ala-Ala-Lys-OH.	Glycine	173-176	high mobility group nucleosome binding domain 1	Homo sapiens	120-126
6778858-3	1980	In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM.	Glycine	164-171	myosin binding protein H	Rattus norvegicus	195-204
7430266-3	1980	L-Proline, 2-aminoisobutyric acid, and glycine were primarily taken up by system A; L-alanine and L-serine by system ASC; L-phenylalanine by system L; and L-lysine by system Ly+ in SV3T3 cells.	Glycine	39-46	steroid sulfatase	Mus musculus	117-120
6987534-4	1980	A dodecapeptide analogue [des-Ala, Gly] His-D-Trp-SRIF (Wy-41, 747) has been identified that combines selective inhibition of GH and glucagon release with prolonged activity.	Glycine	35-38	gonadotropin releasing hormone receptor	Rattus norvegicus	126-128
32245432-3	2020	RESULTS: In the previous study combined multi-omics integrative analysis and amino acid supplementation experiment, we predicted four amino acids (alanine, glutamate, glycine and aspartate) as the limited precursors for glucoamylase production in A. niger.	Glycine	167-174	ANI_1_820034	Aspergillus niger CBS 513.88	220-232
6988046-2	1980	On incubation with the mouse brain extract, the naturally occurring Met-enkephalin was completely destroyed within 5 min and 50% of (D-Ala2)Met-enkephalinamide was degraded within 2 1/2 hr, with the release of Tyr, Phe, Met, D-Ala-Gly and partially (D-)Ala and Gly.	Glycine	231-234	pro-opiomelanocortin-alpha	Mus musculus	68-82
32309365-12	2020	Further mechanistic investigations indicated that the protective effect of PREP disruption on liver inflammation was associated with the suppressed production of matrix metalloproteinases (MMPs) and proline-glycine-proline (PGP) and the inhibition of neutrophil infiltration.	Glycine	207-214	prolyl endopeptidase	Mus musculus	75-79
7205942-18	1980	Renal dipeptidase catalyzed hydrolysis of L-Ala.Gly but not D-Ala.Gly, as was the case with microvilli-catalyzed hydrolysis of the dipeptides.	Glycine	48-51	dipeptidase 1	Homo sapiens	0-17
32111919-1	2020	The alanine-serine-cysteine transporter Asc-1 regulates the synaptic availability of D-serine and glycine (the two co-agonists of the NMDA receptor) and is regarded as an important drug target.	Glycine	98-105	solute carrier family 7 member 10	Homo sapiens	40-45
7205942-18	1980	Renal dipeptidase catalyzed hydrolysis of L-Ala.Gly but not D-Ala.Gly, as was the case with microvilli-catalyzed hydrolysis of the dipeptides.	Glycine	66-69	dipeptidase 1	Homo sapiens	0-17
871045-3	1977	Mathematical computer-assisted programs developed to aid in determining clusters of amino acid variables suggested that excretion of glycine, leucine, proline, and glutamic acid in men and concentrations of valine, serine, aspartic acid, phenylalanine, and lysine in women vary according to the invasiveness of the disease.	Glycine	133-140	activation induced cytidine deaminase	Homo sapiens	53-56
31777253-6	2020	Prairie vole amylin has an unusual sequence compared to those of human and rat amylin, including nonconservative Lys-1 to Glu and Asn-22 to Gly substitutions.	Glycine	140-143	islet amyloid polypeptide	Homo sapiens	13-19
1260011-1	1976	A major glycoprotein 36 000 molecular weight) has been isolated from lung lavage of patients with alveolar proteinosis and found to contain five residues of hydroxyproline, fifty residues of glycine, three residues of methionine, 3 mol of sialic acid, 4.4 mol of mannose, 4.0 mol of galactose, 6.0 mol of glucosamine, and 1 mol of fucose.	Glycine	191-198	podoplanin	Homo sapiens	8-23
31803749-0	2019	Glycine Protects Muscle Cells From Wasting in vitro via mTORC1 Signaling.	Glycine	0-7	CREB regulated transcription coactivator 1	Mus musculus	56-62
31803749-6	2019	The mTORC1 inhibitor rapamycin prevented the glycine-stimulated protection of myotube diameter, and glycine-stimulated S6 phosphorylation, suggesting that mTORC1 signaling may be necessary for glycine"s protective effects in vitro.	Glycine	45-52	CREB regulated transcription coactivator 1	Mus musculus	4-10
31803749-6	2019	The mTORC1 inhibitor rapamycin prevented the glycine-stimulated protection of myotube diameter, and glycine-stimulated S6 phosphorylation, suggesting that mTORC1 signaling may be necessary for glycine"s protective effects in vitro.	Glycine	100-107	CREB regulated transcription coactivator 1	Mus musculus	155-161
31803749-6	2019	The mTORC1 inhibitor rapamycin prevented the glycine-stimulated protection of myotube diameter, and glycine-stimulated S6 phosphorylation, suggesting that mTORC1 signaling may be necessary for glycine"s protective effects in vitro.	Glycine	100-107	CREB regulated transcription coactivator 1	Mus musculus	155-161
31591185-4	2019	The interaction between RhoB and Arf6 is mediated by the GCI (glycine, cysteine, and isoleucine) residues (188-190) of RhoB.	Glycine	62-69	ras homolog family member B	Homo sapiens	24-28
31591185-4	2019	The interaction between RhoB and Arf6 is mediated by the GCI (glycine, cysteine, and isoleucine) residues (188-190) of RhoB.	Glycine	62-69	ras homolog family member B	Homo sapiens	119-123
1052169-0	1976	Separation of human hemoglobins by DEAE-cellulose chromatography using glycine-KCN-NaC1 developers.	Glycine	71-78	nucleus accumbens associated 1	Homo sapiens	83-87
31690066-4	2019	However, opposite to multiallelic classical MHC I genes, HLA-E in fact has only two alleles-HLA-E*01:01 and HLA-E*01:03-which differ by one nonsynonymous amino acid substitution at position 107, resulting in an arginine in HLA-E*01:01 (HLA-ER) and glycine in HLA-E*01:03 (HLA-EG).	Glycine	248-255	major histocompatibility complex, class I, E	Homo sapiens	57-62
1052169-1	1976	This chromatographic procedure uses DEAE-cellulose as ion exchanger and glycine-KCN-NaC1 solutions as developers.	Glycine	72-79	nucleus accumbens associated 1	Homo sapiens	84-88
4362331-7	1973	Compared with growth on glucose, growth on nitrilotriacetate results in increased activities of enzymes of glycine and serine metabolism, namely serine hydroxymethyltransferase, glycine decarboxylase, serine-oxaloacetate aminotransferase and hydroxypyruvate reductase.	Glycine	107-114	glycine decarboxylase	Homo sapiens	178-199
30973753-6	2019	PSAT1 is required for de novo glycine production while ALDH18A1/P5CS is required for de novo proline production.	Glycine	30-37	phosphoserine aminotransferase 1	Homo sapiens	0-5
30403741-9	2018	C. glycines shares some conservation of gene order with other members of the Pleosporales, most notably nad6-rnl-atp6 and associated conserved tRNA clusters.	Glycine	3-11	nad6	Glycine max	104-108
18116440-0	1949	Effect of glycine upon action of insulin in rabbits.	Glycine	10-17	insulin	Oryctolagus cuniculus	33-40
29125030-5	2018	Moreover, the residue interaction networks analysis, the hydrogen bond occupancy analysis and the binding free energies were calculated to gain detailed insight into the influence of the mutant D61G on the two regions, revealing that the major differences between SHP2-WT and SHP2-D61G were the different interactions between Gly 61 and Gly 462, Gly 61 and Ala 461, Gln 506 and Ile 463, Gly 61 and Asn 58, Ile 463 and Thr 466, Gly 462 and Cys 459.	Glycine	326-329	protein tyrosine phosphatase, non-receptor type 11	Mus musculus	276-280
29125030-5	2018	Moreover, the residue interaction networks analysis, the hydrogen bond occupancy analysis and the binding free energies were calculated to gain detailed insight into the influence of the mutant D61G on the two regions, revealing that the major differences between SHP2-WT and SHP2-D61G were the different interactions between Gly 61 and Gly 462, Gly 61 and Ala 461, Gln 506 and Ile 463, Gly 61 and Asn 58, Ile 463 and Thr 466, Gly 462 and Cys 459.	Glycine	337-340	protein tyrosine phosphatase, non-receptor type 11	Mus musculus	276-280
29125030-5	2018	Moreover, the residue interaction networks analysis, the hydrogen bond occupancy analysis and the binding free energies were calculated to gain detailed insight into the influence of the mutant D61G on the two regions, revealing that the major differences between SHP2-WT and SHP2-D61G were the different interactions between Gly 61 and Gly 462, Gly 61 and Ala 461, Gln 506 and Ile 463, Gly 61 and Asn 58, Ile 463 and Thr 466, Gly 462 and Cys 459.	Glycine	337-340	protein tyrosine phosphatase, non-receptor type 11	Mus musculus	276-280
31502061-4	2019	Galectin-3 is the only member of the chimeric galectins that has an N-terminal glycine and proline domain and a C-terminal carbohydrate recognition domain that allows galectin-3 to accommodate larger structures such us polylactosaminoglycans and intervene to DNA damage repair process.	Glycine	79-86	galectin 3	Homo sapiens	0-10
31623094-5	2019	Based on the results of genetic, histological, molecular, and biochemical analyses in an allelic series of Drosophila col4a1 mutants, we provide evidence that col4a1 mutations arise by transitions in glycine triplets, associate with severely compromised muscle fibers within the single-layer striated muscle of the common oviduct, characterized by loss of sarcomere structure, disintegration and streaming of Z-discs, indicating an essential role for the COL4A1 protein.	Glycine	200-207	Collagen type IV alpha 1	Drosophila melanogaster	159-165
33609296-5	2021	Rather than impacting methionine or cysteine, ACT with CTH overexpression unexpectedly reduced glycine, serine and proline concentration within the tumor interstitial fluid.	Glycine	95-102	cystathionase (cystathionine gamma-lyase)	Mus musculus	55-58
31548413-0	2019	The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle.	Glycine	45-52	3-phosphoglycerate dehydrogenase	Mus musculus	84-89
30011082-6	2018	Results show that the primary interaction of p67phox with Nox2 is followed by a stabilizing step, based on the establishment of disulfide bonds between cysteine(s) in the 369 Cys-Gly-Cys371 triad and cysteine(s) in p67phox .	Glycine	179-182	neutrophil cytosolic factor 2	Homo sapiens	45-52
33890291-1	2021	The glycine cleavage system H protein (GCSH) is an integral part of the glycine cleavage system with its additional involvement in the synthesis and transport of lipoic acid.	Glycine	4-11	glycine cleavage system protein H	Homo sapiens	39-43
30187927-4	2018	Herein, we demonstrate that the Asc-1 subtype of neutral amino acid (nAA) transporters that regulates d-serine and glycine release from neurons could be viewed as one of these targets.	Glycine	115-122	solute carrier family 7 member 10	Rattus norvegicus	32-37
30337557-6	2018	Thus, a GCSH-equilibrium at the transcript level is likely conceivable for optimal glycine degradation.	Glycine	83-90	glycine cleavage system protein H	Homo sapiens	8-12
31351182-4	2019	The phylogenetic results show that CAOs can be classified based on two residues, X1 and X2, from the active site motif: T/S-X1-X2-N-Y-D. Residue X2 discriminates among the AOC1 (Tyr), AOC2 (Gly), and AOC3/AOC4 (Leu) proteins, while residue X1 further classifies the AOC3 (Leu) and AOC4 (Met) proteins that so far have been poorly identified and annotated.	Glycine	190-193	amine oxidase copper containing 1	Homo sapiens	172-176
31351182-4	2019	The phylogenetic results show that CAOs can be classified based on two residues, X1 and X2, from the active site motif: T/S-X1-X2-N-Y-D. Residue X2 discriminates among the AOC1 (Tyr), AOC2 (Gly), and AOC3/AOC4 (Leu) proteins, while residue X1 further classifies the AOC3 (Leu) and AOC4 (Met) proteins that so far have been poorly identified and annotated.	Glycine	190-193	amine oxidase copper containing 3	Homo sapiens	200-204
31351182-4	2019	The phylogenetic results show that CAOs can be classified based on two residues, X1 and X2, from the active site motif: T/S-X1-X2-N-Y-D. Residue X2 discriminates among the AOC1 (Tyr), AOC2 (Gly), and AOC3/AOC4 (Leu) proteins, while residue X1 further classifies the AOC3 (Leu) and AOC4 (Met) proteins that so far have been poorly identified and annotated.	Glycine	190-193	amine oxidase copper containing 4, pseudogene	Homo sapiens	205-209
31351182-4	2019	The phylogenetic results show that CAOs can be classified based on two residues, X1 and X2, from the active site motif: T/S-X1-X2-N-Y-D. Residue X2 discriminates among the AOC1 (Tyr), AOC2 (Gly), and AOC3/AOC4 (Leu) proteins, while residue X1 further classifies the AOC3 (Leu) and AOC4 (Met) proteins that so far have been poorly identified and annotated.	Glycine	190-193	amine oxidase copper containing 3	Homo sapiens	266-270
31351182-4	2019	The phylogenetic results show that CAOs can be classified based on two residues, X1 and X2, from the active site motif: T/S-X1-X2-N-Y-D. Residue X2 discriminates among the AOC1 (Tyr), AOC2 (Gly), and AOC3/AOC4 (Leu) proteins, while residue X1 further classifies the AOC3 (Leu) and AOC4 (Met) proteins that so far have been poorly identified and annotated.	Glycine	190-193	amine oxidase copper containing 4, pseudogene	Homo sapiens	281-285
31173968-2	2019	This regulation is based on inhibition of translation of the virally-encoded EBNA1 mRNA, and involves the interaction of host protein nucleolin (NCL) with G-quadruplex (G4) structures that form in the glycine-alanine repeat (GAr)-encoding sequence of the EBNA1 mRNA.	Glycine	201-208	nucleolin	Homo sapiens	134-143
31173968-2	2019	This regulation is based on inhibition of translation of the virally-encoded EBNA1 mRNA, and involves the interaction of host protein nucleolin (NCL) with G-quadruplex (G4) structures that form in the glycine-alanine repeat (GAr)-encoding sequence of the EBNA1 mRNA.	Glycine	201-208	nucleolin	Homo sapiens	145-148
31270129-4	2019	GlyT2 is the only SLC6 family member known to translocate glycine, Na+, and Cl- in a 1:3:1 stoichiometry.	Glycine	58-65	solute carrier family 6 member 5	Homo sapiens	0-5
31152925-0	2019	Improving breast cancer therapy using doxorubicin loaded solid lipid nanoparticles: Synthesis of a novel arginine-glycine-aspartic tripeptide conjugated, pH sensitive lipid and evaluation of the nanomedicine in vitro and in vivo.	Glycine	114-121	phenylalanine hydroxylase	Homo sapiens	154-156
31152925-2	2019	To overcome the toxic side effects and multidrug resistance (MDR) during doxorubicin (DOX) chemotherapy, an arginine-glycine-aspartic (RGD) tripeptide modified, pH-sensitive solid lipid nanoparticles (SLNs) is employed in this study.	Glycine	117-124	phenylalanine hydroxylase	Homo sapiens	161-163
33890291-2	2021	We hypothesize that pathogenic variants in GCSH can cause variant nonketotic hyperglycinemia (NKH), a heterogeneous group of disorders with findings resembling a combination of severe NKH (elevated levels of glycine in plasma and CSF, progressive lethargy, seizures, severe hypotonia, no developmental progress, early death) and mitochondriopathies (lactic acidosis, leukoencephalopathy and Leigh-like lesions on MRI).	Glycine	82-89	glycine cleavage system protein H	Homo sapiens	43-47
33918652-4	2021	Mutation of critical glycine residues required for normal NEDD8 processing resulted in a non-cleavable fusion protein that was rapidly degraded within the cells by both the proteasome and autophagy.	Glycine	21-28	NEDD8 ubiquitin like modifier	Homo sapiens	58-63
31298425-1	2019	Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of serine and tetrahydrofolate (THF) to glycine and methylenetetrahydrofolate.	Glycine	109-116	serine hydroxymethyltransferase	Bombyx mori	0-31
31298425-1	2019	Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of serine and tetrahydrofolate (THF) to glycine and methylenetetrahydrofolate.	Glycine	109-116	serine hydroxymethyltransferase	Bombyx mori	33-37
29944916-9	2018	Among others, alpha-ketoglutarate, hydroxyglutarate and certain amino acids (ornithine, proline and glycine) were reduced in the CS patient fibroblasts, whereas glycolytic intermediates (glucose-6-phosphate and pyruvic acid) and fatty acids (palmitic, stearic and myristic acid) were increased.	Glycine	100-107	citrate synthase	Homo sapiens	129-131
33869785-6	2021	Our gene expression profiling and molecular characterization revealed that Snail actively suppressed the expression of glycine decarboxylase (GLDC), a key enzyme on the serine/glycine metabolic shunt, through binding to an evolutionarily conserved E-box motif and thereby inhibiting the promoter of the GLDC gene.	Glycine	119-126	glycine decarboxylase	Homo sapiens	142-146
33869785-6	2021	Our gene expression profiling and molecular characterization revealed that Snail actively suppressed the expression of glycine decarboxylase (GLDC), a key enzyme on the serine/glycine metabolic shunt, through binding to an evolutionarily conserved E-box motif and thereby inhibiting the promoter of the GLDC gene.	Glycine	119-126	glycine decarboxylase	Homo sapiens	303-307
33755704-10	2021	Notably, we have found a D614G (aspartic acid to glycine) mutation in spike protein of the sequences from the GH clade.	Glycine	49-56	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	70-75
33741598-4	2021	We then identified heptad repeat 2 (HR2) in S2 as the cause of spike metastability, designed an HR2-deleted glycine-capped spike (S2GDeltaHR2), and displayed S2GDeltaHR2 on SApNPs.	Glycine	108-115	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	123-128
29873416-0	2018	EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis.	Glycine	113-120	EWS RNA binding protein 1	Homo sapiens	0-3
29873416-4	2018	Here, we demonstrate that EWS-FLI1 positively regulates the expression of proteins required for serine-glycine biosynthesis and uptake of the alternative nutrient source glutamine.	Glycine	103-110	EWS RNA binding protein 1	Homo sapiens	26-29
29873416-7	2018	Inhibition of serine-glycine biosynthesis in EWS cells impacts their redox state leading to an accumulation of reactive oxygen species, DNA damage, and apoptosis.	Glycine	21-28	EWS RNA binding protein 1	Homo sapiens	45-48
31076642-0	2019	Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.	Glycine	76-79	complement component 3	Mus musculus	0-13
33526384-4	2021	We introduced the human mesotrypsin evolutionary signature mutation into mouse cationic trypsinogen (isoform T7), resulting in a Gly to Arg change at the corresponding position 199.	Glycine	129-132	serine protease 3	Homo sapiens	24-35
30834435-7	2019	Residues corresponding to Gly-202 and Gly-214 in the related transporter SLC35A1 form a substrate-translocating channel, suggesting that a similar mechanism may be involved in SLC35A2.	Glycine	38-41	solute carrier family 35 member A2	Homo sapiens	176-183
30120350-4	2018	A yeast two-hybrid assay revealed that the interaction between OsABIL2 and a putative rice ABA receptor, OsPYL1, was ABA-dependent, and the interaction was lost with amino acid substitution from glycine to aspartic acid at the 183rd amino acid of the OsABIL2 protein, corresponding to abi1-1 mutation.	Glycine	195-202	Protein phosphatase 2C family protein	Arabidopsis thaliana	285-289
30084355-4	2018	Cells lacking Scs2/Scs22 performed spindle positioning via MT end capture-shrinkage mechanism, requiring dynein anchorage to an ER- and mitochondria-independent population of Num1, dynein motor activity, and CAP-Gly domain of dynactin Nip100/p150Glued subunit.	Glycine	212-215	phosphatidylinositol-binding protein SCS2	Saccharomyces cerevisiae S288C	14-18
33633558-18	2020	We postulate that additional glycine sources, possibly the antiporter Asc-1, contribute to RRP replenishment at these high-fidelity brainstem synapses.	Glycine	29-36	solute carrier family 7 member 10	Homo sapiens	70-75
29864719-6	2018	Additionally, three analogues of GHRPs were identified as Gly-GHRP-6, Gly-GHRP-2 and Gly-Ipamorelin, representing the corresponding GHRP extended by a N-terminal glycine residue.	Glycine	58-61	growth hormone secretagogue receptor	Homo sapiens	33-37
29864719-6	2018	Additionally, three analogues of GHRPs were identified as Gly-GHRP-6, Gly-GHRP-2 and Gly-Ipamorelin, representing the corresponding GHRP extended by a N-terminal glycine residue.	Glycine	58-61	growth hormone secretagogue receptor	Homo sapiens	62-66
29864719-6	2018	Additionally, three analogues of GHRPs were identified as Gly-GHRP-6, Gly-GHRP-2 and Gly-Ipamorelin, representing the corresponding GHRP extended by a N-terminal glycine residue.	Glycine	58-61	growth hormone secretagogue receptor	Homo sapiens	62-66
29864719-6	2018	Additionally, three analogues of GHRPs were identified as Gly-GHRP-6, Gly-GHRP-2 and Gly-Ipamorelin, representing the corresponding GHRP extended by a N-terminal glycine residue.	Glycine	70-73	growth hormone secretagogue receptor	Homo sapiens	33-37
29864719-6	2018	Additionally, three analogues of GHRPs were identified as Gly-GHRP-6, Gly-GHRP-2 and Gly-Ipamorelin, representing the corresponding GHRP extended by a N-terminal glycine residue.	Glycine	162-169	growth hormone secretagogue receptor	Homo sapiens	33-37
29864719-6	2018	Additionally, three analogues of GHRPs were identified as Gly-GHRP-6, Gly-GHRP-2 and Gly-Ipamorelin, representing the corresponding GHRP extended by a N-terminal glycine residue.	Glycine	162-169	growth hormone secretagogue receptor	Homo sapiens	62-66
29864719-6	2018	Additionally, three analogues of GHRPs were identified as Gly-GHRP-6, Gly-GHRP-2 and Gly-Ipamorelin, representing the corresponding GHRP extended by a N-terminal glycine residue.	Glycine	162-169	growth hormone secretagogue receptor	Homo sapiens	62-66
30058264-10	2018	The glycine ligand to NMDAR1 subunits was also changed.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	22-28
30196019-5	2018	In these diabetic rats, glycine attenuated renal damage, as evidenced by the decreased mesangial expansion, tubular interstitial fibrosis, and neutrophil gelatinase-associated lipocalin (NGAL) expression.	Glycine	24-31	lipocalin 2	Rattus norvegicus	143-185
30196019-5	2018	In these diabetic rats, glycine attenuated renal damage, as evidenced by the decreased mesangial expansion, tubular interstitial fibrosis, and neutrophil gelatinase-associated lipocalin (NGAL) expression.	Glycine	24-31	lipocalin 2	Rattus norvegicus	187-191
29988937-3	2018	Fifty-two variants tagging (r2 &lt; 0.9) the four GCS genes were tested; one variant, GLDC rs2297442-G, was significantly associated (p = .0007) with decreased glycine concentrations in serum.	Glycine	160-167	glycine decarboxylase	Homo sapiens	86-90
29922054-5	2018	With the expression of Arg-Gly-Asp peptide in the gelatin, the TGF-beta1@MAGNCs have an inherent affinity for chondrogenic ATDC5 cells.	Glycine	27-30	transforming growth factor, beta 1	Mus musculus	63-72
29604130-8	2018	Four of these RNF146 motifs represent novel, extended TBMs, that have one or two additional amino acids between the most conserved Arg and Gly residues.	Glycine	139-142	ring finger protein 146	Homo sapiens	14-20
29868052-1	2018	Serine hydroxymethyltransferase (SHMT, EC 2.1.2.1) is a pyridoxal 5"-phosphate (PLP)-dependent enzyme which catalyzes the reversible serine-to-glycine conversion in either a tetrahydrofolate-dependent or -independent manner.	Glycine	143-150	serine hydroxymethyltransferase, mitochondrial	Medicago truncatula	0-31
29868052-1	2018	Serine hydroxymethyltransferase (SHMT, EC 2.1.2.1) is a pyridoxal 5"-phosphate (PLP)-dependent enzyme which catalyzes the reversible serine-to-glycine conversion in either a tetrahydrofolate-dependent or -independent manner.	Glycine	143-150	serine hydroxymethyltransferase, mitochondrial	Medicago truncatula	33-37
29019702-10	2018	These results indicate that the de novo serine and glycine synthesis pathway is necessary for TGF-beta-induced collagen synthesis and bleomycin-induced pulmonary fibrosis.	Glycine	51-58	transforming growth factor, beta 1	Mus musculus	94-102
29019702-11	2018	PHGDH and other enzymes in the de novo serine and glycine synthesis pathway may be a therapeutic target for treatment of fibrotic diseases, including idiopathic pulmonary fibrosis.	Glycine	50-57	3-phosphoglycerate dehydrogenase	Mus musculus	0-5
29670344-1	2018	Objective: The aim of this study was to evaluate the cost-effectiveness of the long-acting beta-2 agonist (LABA)/long-acting muscarinic antagonist (LAMA) dual bronchodilator indacaterol/glycopyrronium (IND/GLY) as a maintenance treatment for COPD patients from the perspective of health care payer in Taiwan.	Glycine	206-209	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	91-97
29529288-11	2018	Gene sequencing found that the RyR 4946 gene site was glycine (G) in the S, Rf, and Rh strains, and was glutamate (E) with 70% and 80% frequency in the Rb and Rz populations, respectively.	Glycine	54-61	ryanodine receptor	Plutella xylostella	31-34
29351412-4	2018	In this report, we present experimental evidence showing that ECM stimulates the synthesis of CTGF in response to lysophosphatidic acid (LPA).The integrin/focal adhesion kinase (FAK) signaling pathway mediates this effect, since CTGF expression is abolished by the use of the Arg-Gly-Asp-Ser peptide and also by an inhibitor of FAK autophosphorylation at tyrosine 397.	Glycine	280-283	cellular communication network factor 2	Mus musculus	94-98
29549925-10	2018	CONCLUSIONS: The results demonstrate that Gly/Gly polymorphism in Arg389Gly ADRB1 was an independent risk factor together with high fasting plasma glucose, smoking and high triglyceride; moreover, the patients who carried the Gly389Gly genotype had a significantly improved metoprolol antihypertensive effect than those with ADRB1.	Glycine	46-49	adrenoceptor beta 1	Homo sapiens	325-330
29288497-3	2018	Most ARS genes in these cellular compartments are distinct, but two genes are common, encoding aminoacyl-tRNA synthetases of glycine (GARS) and lysine (KARS) in both mitochondria and the cytosol.	Glycine	125-132	RIEG2	Homo sapiens	5-8
29426960-8	2018	The mutation G659D is in the SH3 (Src homology 3) domain of CASK, replacing a semi-conserved glycine with aspartate.	Glycine	93-100	calcium/calmodulin dependent serine protein kinase	Homo sapiens	60-64
29490687-1	2018	BACKGROUND: Dynactin p150Glued, the largest subunit of the dynactin macromolecular complex, binds to both microtubules and tubulin dimers through the N-terminal cytoskeleton-associated protein and glycine-rich (CAP-Gly) and basic domains, and serves as an anti-catastrophe factor in stabilizing microtubules in neurons.	Glycine	197-204	dynactin 1	Mus musculus	21-30
29490687-1	2018	BACKGROUND: Dynactin p150Glued, the largest subunit of the dynactin macromolecular complex, binds to both microtubules and tubulin dimers through the N-terminal cytoskeleton-associated protein and glycine-rich (CAP-Gly) and basic domains, and serves as an anti-catastrophe factor in stabilizing microtubules in neurons.	Glycine	215-218	dynactin 1	Mus musculus	21-30
29490687-3	2018	Multiple missense mutations at the CAP-Gly domain of p150Glued are associated with motor neuron diseases and other neurodegenerative disorders, further supporting the importance of microtubule domains (MTBDs) in p150Glued functions.	Glycine	39-42	dynactin 1	Mus musculus	53-62
29490687-3	2018	Multiple missense mutations at the CAP-Gly domain of p150Glued are associated with motor neuron diseases and other neurodegenerative disorders, further supporting the importance of microtubule domains (MTBDs) in p150Glued functions.	Glycine	39-42	dynactin 1	Mus musculus	212-221
28050793-0	2018	Glycine Administration Alters MAPK Signaling Pathways and Causes Neuronal Damage in Rat Brain: Putative Mechanisms Involved in the Neurological Dysfunction in Nonketotic Hyperglycinemia.	Glycine	0-7	mitogen activated protein kinase 3	Rattus norvegicus	30-34
28050793-7	2018	GLY also decreased the phosphorylation of p38, ERK1/2, and JNK 30 min after its administration in both brain structures.	Glycine	0-3	mitogen activated protein kinase 14	Rattus norvegicus	42-45
28050793-7	2018	GLY also decreased the phosphorylation of p38, ERK1/2, and JNK 30 min after its administration in both brain structures.	Glycine	0-3	mitogen activated protein kinase 3	Rattus norvegicus	47-53
28050793-8	2018	Moreover, GLY-induced decrease of p38 phosphorylation in striatum was attenuated by N-methyl-D-aspartate receptor antagonist MK-801.	Glycine	10-13	mitogen activated protein kinase 14	Rattus norvegicus	34-37
28050793-10	2018	It may be presumed that the decreased phosphorylation of MAPK associated with alterations of markers of neuronal injury induced by GLY may contribute to the neurological dysfunction observed in NKH.	Glycine	131-134	mitogen activated protein kinase 3	Rattus norvegicus	57-61
28803402-6	2018	The inhibition of actin dynamics by treatment with latrunculin B or jasplakinolide and the disruption of the adhesion between the PM and the CW by treatment with RGDS peptide (Arg-Gly-Asp-Ser) enhanced guard cell plasmolysis.	Glycine	180-183	ral guanine nucleotide dissociation stimulator	Homo sapiens	162-166
29285162-4	2017	An MTT assay was used to detect the effects of bFGF and FN on osteoblast adhesion or proliferation on cell/scaffold constructs through blocking the extracellular matrix FN-integrin pathway by the Gly-Arg-Gly-Asp-Ser (GRGDS) peptide.	Glycine	196-199	fibroblast growth factor 2	Rattus norvegicus	47-51
28768147-5	2017	Engineered PAHs contain a secretion peptide, a gastrointestinal signal (GI), the human PAH, and a flexible glycine linker followed by the fluorescence protein mEGFP.	Glycine	107-114	phenylalanine hydroxylase	Homo sapiens	11-14
29141214-4	2017	Similarly, the inability to use glycine as a one-carbon donor to the folate cycle causes NTDs in glycine decarboxylase (Gldc)-deficient embryos.	Glycine	32-39	glycine decarboxylase	Homo sapiens	97-118
29141214-4	2017	Similarly, the inability to use glycine as a one-carbon donor to the folate cycle causes NTDs in glycine decarboxylase (Gldc)-deficient embryos.	Glycine	32-39	glycine decarboxylase	Homo sapiens	120-124
29084578-8	2017	Notably, while pharmacological inhibition of mTORC1 signaling significantly diminished glycine-induced changes in spine morphology, transient genetic upregulation of mTORC1 signaling was insufficient to produce spine enlargements on its own.	Glycine	87-94	CREB regulated transcription coactivator 1	Mus musculus	45-51
29262567-8	2017	Finally, several chemicals including Glycine that may repress GC progression through upregulating HNRNPK are suggested.	Glycine	37-44	heterogeneous nuclear ribonucleoprotein K	Homo sapiens	98-104
28665049-10	2017	Gly-Phe-CHN2 also inhibited the LTB4 -activated-NPs and NP-elastase activities.	Glycine	0-3	chimerin 2	Rattus norvegicus	8-12
28665049-11	2017	Following stimulation of calcium ionophore, the net-releases of DPPI and beta-hexosaminidase from MCs were increased over a time-course, while Gly-Phe-CHN2 down-regulated MCs and NPs activation.	Glycine	143-146	chimerin 2	Rattus norvegicus	151-155
28734869-2	2017	The neuronal glycine transporter 2 (GlyT2) is involved in the recycling of synaptic glycine from the inhibitory synaptic cleft and its activity modulates intra and extracellular glycine concentrations.	Glycine	13-20	solute carrier family 6 member 5	Homo sapiens	36-41
28734869-2	2017	The neuronal glycine transporter 2 (GlyT2) is involved in the recycling of synaptic glycine from the inhibitory synaptic cleft and its activity modulates intra and extracellular glycine concentrations.	Glycine	84-91	solute carrier family 6 member 5	Homo sapiens	13-34
28734869-2	2017	The neuronal glycine transporter 2 (GlyT2) is involved in the recycling of synaptic glycine from the inhibitory synaptic cleft and its activity modulates intra and extracellular glycine concentrations.	Glycine	84-91	solute carrier family 6 member 5	Homo sapiens	36-41
28922356-7	2017	We also explored four theoretical combined methods for Gag suppression, and hypothesized that the N-terminal glycine residue of the MA domain of Gag might be a promising drug target.	Glycine	109-116	Pr55(Gag)	Human immunodeficiency virus 1	55-58
28922356-7	2017	We also explored four theoretical combined methods for Gag suppression, and hypothesized that the N-terminal glycine residue of the MA domain of Gag might be a promising drug target.	Glycine	109-116	Pr55(Gag)	Human immunodeficiency virus 1	145-148
28627122-5	2017	In contrast, the anti-hypothermic effect of BGP21, in which the Tyr-Lys-Asp-Gly sequence in BP21 was modified to a Gly-Gly-Gly-Gly sequence, was less than that of BP21.	Glycine	76-79	Blood pressure QTL 21	Rattus norvegicus	92-96
28627122-5	2017	In contrast, the anti-hypothermic effect of BGP21, in which the Tyr-Lys-Asp-Gly sequence in BP21 was modified to a Gly-Gly-Gly-Gly sequence, was less than that of BP21.	Glycine	115-118	Blood pressure QTL 21	Rattus norvegicus	92-96
28627122-5	2017	In contrast, the anti-hypothermic effect of BGP21, in which the Tyr-Lys-Asp-Gly sequence in BP21 was modified to a Gly-Gly-Gly-Gly sequence, was less than that of BP21.	Glycine	115-118	Blood pressure QTL 21	Rattus norvegicus	92-96
28627122-5	2017	In contrast, the anti-hypothermic effect of BGP21, in which the Tyr-Lys-Asp-Gly sequence in BP21 was modified to a Gly-Gly-Gly-Gly sequence, was less than that of BP21.	Glycine	115-118	Blood pressure QTL 21	Rattus norvegicus	92-96
28627136-4	2017	ERH interacts directly in the nucleus with the C-terminal Arg-Gly-rich region of SAFB1/2 and co-localizes with it in the insoluble nuclear fraction.	Glycine	62-65	scaffold attachment factor B	Homo sapiens	81-88
28588066-0	2017	Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site.	Glycine	101-108	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	28-34
27933579-5	2017	Independent mutation of three highly conserved arginines (R122, R131, and R135) to glycine in DmHsp27 results in only one population of higher molecular weight form.	Glycine	83-90	Heat shock protein 27	Drosophila melanogaster	94-101
28358192-8	2017	Its substitution with glycine, which restores the canonical PDI active site CGHC, does not influence the oxidoreductase activity of the protein, which remains marginal, but strongly affects the binding of the cluster.	Glycine	22-29	protein disulfide isomerase	Arabidopsis thaliana	60-63
28179529-3	2017	Since only subsets of Phe/Gly motifs, particularly those within Nup62, Nup98, and Nup153, are recognized by transport receptors (karyopherins) when trafficking large molecular cargos through the NPC, the processing preferences of individual 2Apro predict RV genotype-specific targeting of NPC pathways and cargos.	Glycine	26-29	nucleoporin 98 and 96 precursor	Homo sapiens	71-76
27859401-10	2017	Cloned and sequenced gene part, encoding the mature lipase shows, in comparison with S. aureus lipase 3 (SAL3), a deletion of three residues (LKA) at the N-terminal extremity and a substitution of glycine 208 and isoleucine 226 with an arginine and leucine, respectively.	Glycine	197-204	lipase	Staphylococcus aureus	52-58
27859401-10	2017	Cloned and sequenced gene part, encoding the mature lipase shows, in comparison with S. aureus lipase 3 (SAL3), a deletion of three residues (LKA) at the N-terminal extremity and a substitution of glycine 208 and isoleucine 226 with an arginine and leucine, respectively.	Glycine	197-204	lipase	Staphylococcus aureus	95-101
28045594-0	2017	Human HPRT1 gene and the Lesch-Nyhan disease: Substitution of alanine for glycine and inversely in the HGprt enzyme protein.	Glycine	74-81	hypoxanthine phosphoribosyltransferase 1	Homo sapiens	6-11
27297361-0	2017	A novel mechanism of mTORC1-mediated serine/glycine metabolism in osteosarcoma development.	Glycine	44-51	CREB regulated transcription coactivator 1	Mus musculus	21-27
27297361-7	2017	Results of GC-TOFMS suggested that inhibition of mTORC1 reduce one-carbon amino acids, serine and glycine, in osteosarcoma cells.	Glycine	98-105	CREB regulated transcription coactivator 1	Mus musculus	49-55
27297361-8	2017	Moreover, mTORC1 regulates serine/glycine de novo synthesis via modulating glycolysis and serine/glycine synthesis gene expressions.	Glycine	34-41	CREB regulated transcription coactivator 1	Mus musculus	10-16
27297361-8	2017	Moreover, mTORC1 regulates serine/glycine de novo synthesis via modulating glycolysis and serine/glycine synthesis gene expressions.	Glycine	97-104	CREB regulated transcription coactivator 1	Mus musculus	10-16
27297361-9	2017	Further, mTORC1/serine/glycine metabolic axis promotes osteosarcoma proliferation and antioxidant ability to environmental stress, which finally leads to cell survival.	Glycine	23-30	CREB regulated transcription coactivator 1	Mus musculus	9-15
27297361-10	2017	Our results identify a novel mechanism of mTORC1-mediated serine/glycine metabolism as a significant protective system in osteosarcoma cells.	Glycine	65-72	CREB regulated transcription coactivator 1	Mus musculus	42-48
27808173-4	2016	Moreover, bFGF treatment corrected diabetes-induced reductions in citrate, lactate, choline, glycine, creatine, histidine, phenylalanine, tyrosine and glutamine in serum.	Glycine	93-100	fibroblast growth factor 2	Rattus norvegicus	10-14
27518042-4	2016	The co-repression occurs through binding of TDP-43 to mRNA(s) at specific UG/GU sequences and recruitment of the inhibitory CYFIP1-FMRP complex by its glycine-rich domain.	Glycine	151-158	cytoplasmic FMR1 interacting protein 1	Homo sapiens	124-130
20301531-13	1993	The three genes in which biallelic pathogenic variants are known to cause glycine encephalopathy are: GLDC (encoding the P-protein component of the GCS complex and accounting for 70%-75% of disease), AMT (encoding the T-protein component of the GCS complex and accounting for ~20% of disease), and GCSH (encoding the H-protein component of the GCS complex and accounting for &lt;1% of disease).	Glycine	74-81	glycine decarboxylase	Homo sapiens	102-106
20301531-13	1993	The three genes in which biallelic pathogenic variants are known to cause glycine encephalopathy are: GLDC (encoding the P-protein component of the GCS complex and accounting for 70%-75% of disease), AMT (encoding the T-protein component of the GCS complex and accounting for ~20% of disease), and GCSH (encoding the H-protein component of the GCS complex and accounting for &lt;1% of disease).	Glycine	74-81	glycine cleavage system protein H	Homo sapiens	298-302
31223446-3	2019	Furthermore, the free energy perturbation calculations and molecular dynamics (MD) studies revealed the GlyT2 amino acid residues critical for the binding and selectivity of both Glycine and our Hit1 compound.	Glycine	179-186	solute carrier family 6 member 5	Homo sapiens	104-109
31071163-10	2019	In the next step, gamma-EV was combined with glycine by the glutathione synthetase (GS) Gsh2p.	Glycine	45-52	glutathione synthase	Saccharomyces cerevisiae S288C	88-93
30770653-2	2019	In this study, a vascular endothelial growth factor (VEGF165) and angiopoietin-1 (Ang-1) dual gene coexpression vector that encoded green fluorescent protein (GFP) was constructed from an arginine-glycine-aspartic acid-modified adenovirus.	Glycine	197-204	angiopoietin 1	Homo sapiens	66-80
30770653-2	2019	In this study, a vascular endothelial growth factor (VEGF165) and angiopoietin-1 (Ang-1) dual gene coexpression vector that encoded green fluorescent protein (GFP) was constructed from an arginine-glycine-aspartic acid-modified adenovirus.	Glycine	197-204	angiopoietin 1	Homo sapiens	82-87
30770653-7	2019	In conclusion, SF scaffolds loaded with arginine-glycine-aspartic acid-modified adenovirus vectors encoding VEGF165 and Ang-1 could stimulate the formation of vascular networks through the effective expression of target genes in vascular endothelial cells, thereby accelerating the regeneration of dermal tissue.	Glycine	49-56	angiopoietin 1	Homo sapiens	120-125
30760570-3	2019	The envelope protein (Env) contained a flexible glycine linker and I559P mutation.	Glycine	48-55	endogenous retrovirus group K member 6, envelope	Homo sapiens	4-20
30760570-3	2019	The envelope protein (Env) contained a flexible glycine linker and I559P mutation.	Glycine	48-55	endogenous retrovirus group K member 6, envelope	Homo sapiens	22-25
30659259-5	2019	SLC7A2 was associated with the plasma levels of arginine and ornithine, and PKD1L2 with the level of glycine.	Glycine	101-108	solute carrier family 7 member 2	Homo sapiens	0-6
30659259-6	2019	The significant associations of these two genes were revealed in the conditional QTL analysis, but a significant association between serine and the CPS1 gene disappeared when glycine was used as a covariate.	Glycine	175-182	carbamoyl-phosphate synthase 1	Homo sapiens	148-152
30845140-9	2019	We find that mutations in components of this cycle, methionine synthase (metr-1) and S-adenosylmethionine synthetase (sams-1), completely abrogate glycine-induced lifespan extension.	Glycine	147-154	putative methionine synthase	Caenorhabditis elegans	73-79
30678654-8	2019	The five novel ALAS2 truncation mutations had increased Vmax values for both succinyl-CoA and glycine substrates (1.4 to 5.6-fold over wild-type), while the Kms for both substrates were only modestly changed.	Glycine	94-101	5'-aminolevulinate synthase 2	Homo sapiens	15-20
30522268-1	2019	Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate (THF) to glycine and 5,10-methylene THF.	Glycine	168-175	pyridoxal phosphatase	Homo sapiens	65-68
29675575-6	2019	Our in vivo results showed that GLY increased the activities of the antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), and glucose-6-phosphate dehydrogenase (G6PDH) in striatum.	Glycine	32-35	glucose-6-phosphate dehydrogenase	Rattus norvegicus	178-211
29675575-6	2019	Our in vivo results showed that GLY increased the activities of the antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), and glucose-6-phosphate dehydrogenase (G6PDH) in striatum.	Glycine	32-35	glucose-6-phosphate dehydrogenase	Rattus norvegicus	213-218
31589099-6	2019	Metabolite analysis suggests that activation of glycine-to-serine conversion catalyzed through glycine decarboxylase in conjunction with serine hydroxymethyltransferase in trxo1 is slowed down at onset of illumination.	Glycine	48-55	glycine decarboxylase	Homo sapiens	95-116
30137570-3	2018	Through a forward genetic method, we identified a photorespiratory mutant pr1 (photorespiratory related 1), which produced a chlorotic and smaller photorespiratory growth phenotype with decreased chlorophyll content and accumulation of glycine and serine in ambient air.	Glycine	236-243	pathogenesis-related protein 1	Arabidopsis thaliana	74-77
30403859-6	2018	An electrophysiology-based experiment carried out in Xenopus laevis oocytes expressing AtLHT1 showed that AtLHT1 had a high in vitro affinity for CAP-Gly-1.	Glycine	150-153	lysine histidine transporter 1	Arabidopsis thaliana	87-93
30403859-6	2018	An electrophysiology-based experiment carried out in Xenopus laevis oocytes expressing AtLHT1 showed that AtLHT1 had a high in vitro affinity for CAP-Gly-1.	Glycine	150-153	lysine histidine transporter 1	Arabidopsis thaliana	106-112
29125030-5	2018	Moreover, the residue interaction networks analysis, the hydrogen bond occupancy analysis and the binding free energies were calculated to gain detailed insight into the influence of the mutant D61G on the two regions, revealing that the major differences between SHP2-WT and SHP2-D61G were the different interactions between Gly 61 and Gly 462, Gly 61 and Ala 461, Gln 506 and Ile 463, Gly 61 and Asn 58, Ile 463 and Thr 466, Gly 462 and Cys 459.	Glycine	337-340	protein tyrosine phosphatase, non-receptor type 11	Mus musculus	276-280
29125030-5	2018	Moreover, the residue interaction networks analysis, the hydrogen bond occupancy analysis and the binding free energies were calculated to gain detailed insight into the influence of the mutant D61G on the two regions, revealing that the major differences between SHP2-WT and SHP2-D61G were the different interactions between Gly 61 and Gly 462, Gly 61 and Ala 461, Gln 506 and Ile 463, Gly 61 and Asn 58, Ile 463 and Thr 466, Gly 462 and Cys 459.	Glycine	337-340	protein tyrosine phosphatase, non-receptor type 11	Mus musculus	276-280
30011082-0	2018	Binding of p67phox to Nox2 is stabilized by disulfide bonds between cysteines in the 369 Cys-Gly-Cys371 triad in Nox2 and in p67phox.	Glycine	93-96	neutrophil cytosolic factor 2	Homo sapiens	11-18
30011082-0	2018	Binding of p67phox to Nox2 is stabilized by disulfide bonds between cysteines in the 369 Cys-Gly-Cys371 triad in Nox2 and in p67phox.	Glycine	93-96	neutrophil cytosolic factor 2	Homo sapiens	125-132
30109712-1	2018	The new GnRH-Iotaanalogue developed in this paper was based on the D-Trp6 -GnRH-Iota-scaffold, and its potency was increased by the replacement Gly-NH2 by NH-NH2 binding to the Gly at position 10.	Glycine	144-147	gonadotropin releasing hormone 1	Homo sapiens	8-12
30109712-1	2018	The new GnRH-Iotaanalogue developed in this paper was based on the D-Trp6 -GnRH-Iota-scaffold, and its potency was increased by the replacement Gly-NH2 by NH-NH2 binding to the Gly at position 10.	Glycine	144-147	transient receptor potential cation channel subfamily C member 6	Homo sapiens	69-73
30109712-1	2018	The new GnRH-Iotaanalogue developed in this paper was based on the D-Trp6 -GnRH-Iota-scaffold, and its potency was increased by the replacement Gly-NH2 by NH-NH2 binding to the Gly at position 10.	Glycine	144-147	gonadotropin releasing hormone 1	Homo sapiens	75-79
30181289-2	2018	We demonstrate that substituting H3G34 with arginine, valine, or aspartate (H3G34R/V/D), which converts the non-side chain glycine to a large side chain-containing residue, blocks H3 lysine 36 (H3K36) dimethylation and trimethylation by histone methyltransferases, including SETD2, an H3K36-specific trimethyltransferase.	Glycine	123-130	SET domain containing 2, histone lysine methyltransferase	Homo sapiens	275-280
29966365-2	2018	NR1 and NR3 subunits bind glycine, while NR2 subunits bind glutamate for full activation.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	8-11
29867218-0	2018	A neuronal role of the Alanine-Serine-Cysteine-1 transporter (SLC7A10, Asc-1) for glycine inhibitory transmission and respiratory pattern.	Glycine	82-89	solute carrier family 7 member 10	Homo sapiens	62-69
29867218-0	2018	A neuronal role of the Alanine-Serine-Cysteine-1 transporter (SLC7A10, Asc-1) for glycine inhibitory transmission and respiratory pattern.	Glycine	82-89	solute carrier family 7 member 10	Homo sapiens	71-76
29867218-1	2018	The Alanine-Serine-Cysteine-1 transporter (SLC7A10, Asc-1) has been shown to play a role in synaptic availability of glycine although the exact mechanism remains unclear.	Glycine	117-124	solute carrier family 7 member 10	Homo sapiens	43-50
29867218-1	2018	The Alanine-Serine-Cysteine-1 transporter (SLC7A10, Asc-1) has been shown to play a role in synaptic availability of glycine although the exact mechanism remains unclear.	Glycine	117-124	solute carrier family 7 member 10	Homo sapiens	52-57
29867218-5	2018	These results suggest a role of Asc-1 in modulating presynaptic glycine levels that can impact on the respiratory network.	Glycine	64-71	solute carrier family 7 member 10	Homo sapiens	32-37
29684281-6	2018	A detailed quantum-chemical study combined with experimental data allowed to unravel the role of the {Zr6O8} core of MOF-808 in accelerating Gly-Gly hydrolysis.	Glycine	141-144	lysine acetyltransferase 8	Homo sapiens	117-120
29684281-6	2018	A detailed quantum-chemical study combined with experimental data allowed to unravel the role of the {Zr6O8} core of MOF-808 in accelerating Gly-Gly hydrolysis.	Glycine	145-148	lysine acetyltransferase 8	Homo sapiens	117-120
29576456-5	2018	Phase separation is promoted by multivalent interactions between the glycine/tryptophan (GW)-rich domain of TNRC6B and three evenly spaced tryptophan-binding pockets in the Ago2 PIWI domain.	Glycine	69-76	trinucleotide repeat containing adaptor 6B	Homo sapiens	108-114
29576319-3	2018	The crystal structures of the CAP-Gly domain of Bik1 (Bik1CG) alone and in complex with an ETF peptide revealed unique, functionally relevant CAP-Gly elements, establishing Bik1CG as a specific C-terminal phenylalanine recognition domain.	Glycine	146-149	Bik1p	Saccharomyces cerevisiae S288C	48-52
28895081-4	2018	Trio whole-exome sequencing analysis of DNA samples from the patient and his parents revealed a de novo novel missense mutation (c.1150G>A, p.G384S) in KCND3, the causative gene of SCA19/22, substituting for evolutionally conserved glycine.	Glycine	232-239	trio Rho guanine nucleotide exchange factor	Homo sapiens	0-4
28895081-4	2018	Trio whole-exome sequencing analysis of DNA samples from the patient and his parents revealed a de novo novel missense mutation (c.1150G>A, p.G384S) in KCND3, the causative gene of SCA19/22, substituting for evolutionally conserved glycine.	Glycine	232-239	potassium voltage-gated channel subfamily D member 3	Homo sapiens	152-157
28895081-4	2018	Trio whole-exome sequencing analysis of DNA samples from the patient and his parents revealed a de novo novel missense mutation (c.1150G>A, p.G384S) in KCND3, the causative gene of SCA19/22, substituting for evolutionally conserved glycine.	Glycine	232-239	potassium voltage-gated channel subfamily D member 3	Homo sapiens	181-186
29333938-8	2018	Insertion of two glycines in both the heavy and light chain elbow regions provided sufficient flexibility for the variable domains to extend further apart than the wild-type Fab, and allow the CDR3s to make additional interactions not seen in the wild-type Fab structure.	Glycine	17-25	CDR3	Homo sapiens	193-197
28822114-6	2018	Mutant mice with DMP1 point mutations changing S89 to glycine (S89G), which completely eradicated glycosylation of the protein, demonstrated severe BBB disruption.	Glycine	54-61	dentin matrix protein 1	Mus musculus	17-21
29352967-4	2018	In contrast, 7,8-diol synthases (7,8-LDS), 5,8-LDS, and 8R-DOX-AOS oxidized the Gly conjugates in most case only to small amounts of metabolites, but with retention of hydrogen abstraction at C-8 and relatively minor hydrogen abstraction at C-11.	Glycine	80-83	homeobox C8	Homo sapiens	192-195
29019082-2	2018	TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such as L-glycine and L-glutamate or sweet molecules such as sucrose and fructose when dimerized with TAS1R member 1 (TAS1R1) or TAS1R member 2 (TAS1R2), respectively.	Glycine	87-96	taste receptor, type 1, member 1	Mus musculus	197-203
29251223-7	2018	Via alanine, isoleucine, L-serine dehydratase/L-threonine deaminase and other proteins, AgNP-cit altered the metabolism of glycine, serine and threonine, cysteine and methionine, affecting oxidation and deamination, and ultimately leading to liver damage.	Glycine	123-130	serine dehydratase	Homo sapiens	25-67
29888319-2	2018	We have previously demonstrated that insertion of the internalizing Arginine-Glycine-Aspartic (iRGD) tumor-penetrating peptide at the C terminus of the fiber or transgenic expression of a secreted hyaluronidase can improve virus tumor targeting and spreading.	Glycine	77-84	interferon gamma inducible protein 47	Mus musculus	95-99
29320694-7	2018	The simulations found that an Ile side chain was enough to form a steric barrier that prevents exit of DMXAA, whereas in WT hSTING, the Gly residue that lacks a side chain formed a porous lid region that allowed DMXAA to exit.	Glycine	136-139	stimulator of interferon response cGAMP interactor 1	Homo sapiens	124-130
29175998-6	2017	Corroborated by biochemical experiments and functional studies in yeast, we show that aliphatic residues flanking Tyr257 and Tyr662 are equally important for substrate interaction, and abolish Hsp104 function when mutated to glycine.	Glycine	225-232	chaperone ATPase HSP104	Saccharomyces cerevisiae S288C	193-199
29116138-7	2017	(3) Glycine directly bounded to voltage dependent anion channel 1 (VDAC1) on the mitochondrial outer membrane and inhibited its opening.	Glycine	4-11	voltage dependent anion channel 1	Homo sapiens	32-65
29116138-7	2017	(3) Glycine directly bounded to voltage dependent anion channel 1 (VDAC1) on the mitochondrial outer membrane and inhibited its opening.	Glycine	4-11	voltage dependent anion channel 1	Homo sapiens	67-72
29116138-8	2017	These original results highlight glycine as a necessary mediator in VEGF signalling via the GlyT1-glycine-mTOR-VDAC1 axis pathway.	Glycine	33-40	voltage dependent anion channel 1	Homo sapiens	111-116
28754261-5	2017	Phase diagrams of various JM2 formulations were constructed, suggesting that the phase behavior of JM2 was dependent on the solution pH, ionic strength and the presence of other excipients such as glycine, alanine, sorbitol and sucrose.	Glycine	197-204	forkhead box P3	Homo sapiens	99-102
28922740-5	2017	Analysis of the PglB crystal structures from Campylobacter lari and the soluble C-terminal domain from C. jejuni suggests a particularly important structural role for the aspartate residue and the two following glycine residues, as well as a more subtle, less defined role for the lysine residue.	Glycine	211-218	epiphycan	Homo sapiens	16-20
28627122-11	2017	These results suggest that biotinylated peptides, especially BP21, can specifically and markedly inhibit anaphylactic reactions in vivo and that this involves direct interaction of its Tyr-Lys-Asp-Gly region with PAF.	Glycine	197-200	Blood pressure QTL 21	Rattus norvegicus	61-65
29109774-7	2017	We also found a new role of PLM-KSLW in tightening vascular barrier integrity by binding to the glycine/tyrosine-rich domain of occludin (OCLN).	Glycine	96-103	occludin	Homo sapiens	128-136
29109774-7	2017	We also found a new role of PLM-KSLW in tightening vascular barrier integrity by binding to the glycine/tyrosine-rich domain of occludin (OCLN).	Glycine	96-103	occludin	Homo sapiens	138-142
28863211-6	2017	A missense mutation (c.710G &gt; T), which mapped to exon 6 of the Rab GDP-Dissociation Inhibitor 1 (GDI1) gene, was found segregating with the ID phenotype, and this mutation changes the 237th position in the guanosine diphosphate dissociation inhibitor (GDI) protein from glycine to valine (p. Gly237Val).	Glycine	274-281	GDP dissociation inhibitor 1	Homo sapiens	101-105
28543875-5	2017	ISG15 mutants lacking the C-terminal glycine residue that is essential for ISGylation still interacted with NS5A protein.	Glycine	37-44	ISG15 ubiquitin like modifier	Homo sapiens	0-5
28529477-6	2017	Prox1-immunoreactive amacrine cells expressed glycine, and they formed 35 +- 3% of all glycinergic amacrine cells.	Glycine	46-53	prospero homeobox 1	Mus musculus	0-5
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	RNA imprinted and accumulated in nucleus	Mus musculus	160-164
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	miRNA containing gene	Mus musculus	169-173
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	delta like non-canonical Notch ligand 1	Mus musculus	220-224
27665014-3	2017	Both mucin sources are dominated by repetitive O-glycosylated areas dependant on threonine, serine, glycine, and proline.	Glycine	100-107	LOC100508689	Homo sapiens	5-10
28416846-2	2017	The Arg-Gly-Asp-Ser sequence (RGDS) was confirmed of affecting cell adhesion.	Glycine	8-11	ral guanine nucleotide dissociation stimulator	Homo sapiens	30-34
28302935-7	2017	The glycine at amino acid position 435 in the C-terminal region is completely conserved in the trypsin-like serine protease family, including thrombin, FVII, protein C, plasmin, trypsin, and chymotrypsin.	Glycine	4-11	plasminogen	Homo sapiens	169-176
28259896-4	2017	In the folate cycle, glycine and serine fuel the mitochondrial enzymes SHMT2, MTHFD2 and ALDH1L2, which play critical roles in the cancer survival and proliferation presumably through purine production.	Glycine	21-28	aldehyde dehydrogenase 1 family member L2	Homo sapiens	89-96
28401144-0	2017	Insights into the Activity Change of Spore Photoproduct Lyase Induced by Mutations at a Peripheral Glycine Residue.	Glycine	99-106	sphingosine-1-phosphate lyase 1	Homo sapiens	37-61
28000043-2	2017	Three missense mutations for glycine 426 (by standard nomenclature) of TNSALP have been reported: cysteine (p.G426C), serine (p.G426S), and aspartate (p.G426D).	Glycine	29-36	alkaline phosphatase, biomineralization associated	Homo sapiens	71-77
28056489-2	2017	METHOD: Using HFUS, we imaged embryos carrying loss of function alleles of Gldc encoding glycine decarboxylase, a component of the glycine cleavage system in mitochondrial folate metabolism, which is known to be associated with cranial NTDs and NKH in humans.	Glycine	89-96	glycine decarboxylase	Homo sapiens	75-79
26796213-1	2017	d-Serine is a co-agonist of NMDA receptors (NMDARs) whose activity is potentially regulated by Asc-1 (SLC7A10), a transporter that displays high affinity for d-serine and glycine.	Glycine	171-178	anterior suture cataract 1	Mus musculus	95-100
28828604-5	2017	The five additional glycine transporters ATB0,+, SNAT1, SNAT2, SNAT5, and LAT2 display broad amino acid specificity and have differential contributions to glial glycine transport.	Glycine	20-27	linker for activation of T cells family member 2	Homo sapiens	74-78
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	4-11	solute carrier family 7 member 10	Homo sapiens	180-185
28190830-5	2017	The sequence of intermediate peptide GPLG VRGK can act as a target material for matrix metalloproteinases-2 (MMP-2) produced by cancer cells at its Gly and Val region, shown by the down-headed arrow.	Glycine	148-151	matrix metallopeptidase 2	Homo sapiens	80-107
28190830-5	2017	The sequence of intermediate peptide GPLG VRGK can act as a target material for matrix metalloproteinases-2 (MMP-2) produced by cancer cells at its Gly and Val region, shown by the down-headed arrow.	Glycine	148-151	matrix metallopeptidase 2	Homo sapiens	109-114
32512682-1	2016	BACKGROUND: Dentin sialophosphoprotein (DSPP) belongs to the family of small integrin-binding ligand N-linked glycoproteins (SIBLINGs), which share common biochemical features such as an arginine-glycine-aspartic acid (RGD) integrin-binding site.	Glycine	196-203	dentin sialophosphoprotein	Homo sapiens	12-38
32512682-1	2016	BACKGROUND: Dentin sialophosphoprotein (DSPP) belongs to the family of small integrin-binding ligand N-linked glycoproteins (SIBLINGs), which share common biochemical features such as an arginine-glycine-aspartic acid (RGD) integrin-binding site.	Glycine	196-203	dentin sialophosphoprotein	Homo sapiens	40-44
28018459-7	2016	The CLCNKB mutation analysis revealed a heterozygous c.139G&gt;A transition in exon 13 [p.Gly(GGG)465Glu(GAG)].	Glycine	90-93	chloride voltage-gated channel Kb	Homo sapiens	4-10
27544385-7	2017	The nonsense mutation is predicted to result in a truncated TTN protein and the missense mutation leads to a substitution of glycine by arginine.	Glycine	125-132	titin	Homo sapiens	60-63
33740382-11	2021	CONCLUSION: The novel SnF2 dentifrice with the amino acid glycine produced statistically significant improvements in gingival health that were seen as early as 1 week and numerically increased throughout the study.	Glycine	58-65	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Homo sapiens	22-26
28197209-8	2017	And also, we selected Arg-Gly-Asp- (RGD-) conjugated alginate hydrogel for BMP-2 delivery because alginate is able to release BMP-2 in a sustained manner and it is a biocompatible material.	Glycine	26-29	bone morphogenetic protein 2	Homo sapiens	75-80
28197209-8	2017	And also, we selected Arg-Gly-Asp- (RGD-) conjugated alginate hydrogel for BMP-2 delivery because alginate is able to release BMP-2 in a sustained manner and it is a biocompatible material.	Glycine	26-29	bone morphogenetic protein 2	Homo sapiens	126-131
27836973-4	2016	TGF-beta also induces the expression of the enzymes of the de novo serine synthesis pathway (phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine phosphatase (PSPH)) and de novo glycine synthesis (serine hydroxymethyltransferase 2 (SHMT2)).	Glycine	225-232	phosphoglycerate dehydrogenase	Homo sapiens	93-123
27836973-4	2016	TGF-beta also induces the expression of the enzymes of the de novo serine synthesis pathway (phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine phosphatase (PSPH)) and de novo glycine synthesis (serine hydroxymethyltransferase 2 (SHMT2)).	Glycine	225-232	phosphoserine aminotransferase 1	Homo sapiens	167-172
27663665-0	2016	A conserved glycine residue in the C-terminal region of human ATG9A is required for its transport from the endoplasmic reticulum to the Golgi apparatus.	Glycine	12-19	autophagy related 9A	Homo sapiens	62-67
27663665-8	2016	Using sequential amino acid substitutions of glycine 516 and cysteine 519, we found that the stability of ATG9A relies on both of these residues, but that only the former is required for efficient transport of human ATG9A from the endoplasmic reticulum to the Golgi apparatus.	Glycine	45-52	autophagy related 9A	Homo sapiens	106-111
27476175-4	2016	Herein we describe the biochemical and molecular characterization of yeast Hem25p and human SLC25A38, providing evidence that they are mitochondrial carriers for glycine.	Glycine	162-169	solute carrier family 25 member 38	Homo sapiens	92-100
27659424-10	2016	Moreover, hepatic mRNA levels of arginase-1, a marker of macrophage M2 transformation, were significantly increased in glycine diet-fed mice.	Glycine	119-126	arginase, liver	Mus musculus	33-43
27476175-7	2016	Our results identify new proteins in the heme biosynthetic pathway and demonstrate that Hem25p and its human orthologue SLC25A38 are the main mitochondrial glycine transporters required for heme synthesis, providing definitive evidence of their previously proposed glycine transport function.	Glycine	156-163	solute carrier family 25 member 38	Homo sapiens	120-128
33508318-6	2021	Displacement of the Gly-rich loop interferes with a newly identified, structurally conserved binding pocket for the C1a domain on the N lobe of the kinase domain.	Glycine	20-23	endogenous retrovirus group K member 1	Homo sapiens	116-119
33508318-8	2021	SMKI-mediated displacement of the Gly-rich loop released C1a and exposed the DAG binding site, enhancing PKCalpha translocation both to synthetic lipid bilayers and to live cell membranes in the presence of DAG.	Glycine	34-37	endogenous retrovirus group K member 1	Homo sapiens	57-60
33458942-0	2021	The role of prolines and glycine in the transmembrane domain of LAT.	Glycine	25-32	linker for activation of T cells	Homo sapiens	64-67
27686733-1	2016	Hb Zurich-Albisrieden [HBA2: c.178G &gt; C; alpha59(E8)Gly Arg (alpha2)] is a rare nondeletional alpha-thalassemia (alpha-thal) that results from a nucleotide substitution at codon 59 of the alpha2-globin gene.	Glycine	55-58	hemoglobin subunit alpha 2	Homo sapiens	23-27
27851964-2	2016	CAPS1 pre-mRNA is known to undergo adenosine-to-inosine RNA editing in its coding region, which results in a glutamate-to-glycine conversion at a site in its C-terminal region.	Glycine	122-129	Ca2+-dependent secretion activator	Mus musculus	0-5
33458942-4	2021	Here, we studied the impact of helix-breaking amino acids, two prolines and one glycine, in the transmembrane segment on localisation and function of LAT.	Glycine	80-87	linker for activation of T cells	Homo sapiens	150-153
33458942-6	2021	The helical structure and dynamics are further regulated by glycine and another proline residue in the luminal part of LAT transmembrane domain.	Glycine	60-67	linker for activation of T cells	Homo sapiens	119-122
27348081-7	2016	Moreover, ACPA reactivity was not restricted to antigens known to be associated with ACPA-positive RA alone, but also to proteins without relation to RA, primarily illustrating that any protein in theory can be turned into an RA autoantigen, by introducing Cit-Gly motifs.	Glycine	261-264	proteinase 3	Homo sapiens	10-14
32594192-2	2020	Moreover, L-serine is the precursor of two relevant coagonists of NMDA receptors: glycine (through the enzyme serine hydroxymethyltransferase), which preferentially acts on extrasynaptic receptors and D-serine (through the enzyme serine racemase), dominant at synaptic receptors.	Glycine	82-89	serine racemase	Homo sapiens	230-245
26992370-9	2016	Furthermore, it was confirmed that protein immobilization on the polymer occurred through the oxidized MAT units because the protein adsorption was significantly reduced upon blocking these units through pretreatment with glycine.	Glycine	222-229	methionine adenosyltransferase 1A	Homo sapiens	103-106
27225947-0	2016	Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.	Glycine	0-7	nucleotide binding oligomerization domain containing 2	Homo sapiens	115-119
33176720-8	2020	Based on these DE-mRNAs, they were involved in biological processes such as fatty acid beta-oxidation, IRE1-mediated unfolded protein response, and transmembrane transport, and many KEGG pathways like glycine, serine and threonine metabolism, carbon metabolism.	Glycine	201-208	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	103-107
32341465-8	2020	Farnesoid X receptor (FXR) inhibitor glycine-beta-muricholic acid or FXR knockdown reversed the downregulation of PepT1 expression by CDCA and GW4064 (another FXR agonist).	Glycine	37-44	nuclear receptor subfamily 1 group H member 4	Homo sapiens	22-25
27261063-5	2016	Blue light-dependent stomatal opening in the epidermis and H(+) pumping in guard cell protoplasts were inhibited by 70% in blus2 Whole-genome resequencing identified a mutation in the AHA1 gene of the mutant at Gly-602.	Glycine	211-214	activator of HSP90 ATPase activity 1	Homo sapiens	184-188
32901845-6	2020	These two proteins were expressed in three segments and the cross-reactivity of H1-84mAb with the glycine (Gly)-rich domains of hnRNPA1 (195aa-320aa) and hnRNPA2/B1 (202aa-349aa) was determined using ELISA blocking experiments.	Glycine	98-105	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	128-135
27350173-5	2016	Skeletal muscle mRNA expression of serine/one-carbon/glycine biosynthesis pathway genes (Phgdh, Psat1 and Psph) and the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase-M (Pck2/PEPCK-M), increased during treatment with BA, and to a lesser extent GH (p &lt; 0.001, treatment x time interaction).	Glycine	53-60	phosphoglycerate dehydrogenase	Sus scrofa	89-94
27350173-5	2016	Skeletal muscle mRNA expression of serine/one-carbon/glycine biosynthesis pathway genes (Phgdh, Psat1 and Psph) and the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase-M (Pck2/PEPCK-M), increased during treatment with BA, and to a lesser extent GH (p &lt; 0.001, treatment x time interaction).	Glycine	53-60	phosphoserine aminotransferase 1	Sus scrofa	96-101
32901845-6	2020	These two proteins were expressed in three segments and the cross-reactivity of H1-84mAb with the glycine (Gly)-rich domains of hnRNPA1 (195aa-320aa) and hnRNPA2/B1 (202aa-349aa) was determined using ELISA blocking experiments.	Glycine	107-110	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	128-135
33177718-7	2020	Although in all JDPs the interaction of the characteristic J-domain is responsible for the activation of HSP70, in DNAJB1 the HSP70-binding sites in this domain are intrinsically blocked by an adjacent glycine-phenylalanine rich region-an inhibition that can be released upon the interaction of a second site on DNAJB1 with the HSP70 C-terminal tail.	Glycine	202-209	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	115-121
33177718-7	2020	Although in all JDPs the interaction of the characteristic J-domain is responsible for the activation of HSP70, in DNAJB1 the HSP70-binding sites in this domain are intrinsically blocked by an adjacent glycine-phenylalanine rich region-an inhibition that can be released upon the interaction of a second site on DNAJB1 with the HSP70 C-terminal tail.	Glycine	202-209	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	312-318
32263314-3	2016	To this end, we prepared and characterized the matrix metalloprotease-2 (MMP-2)/MMP-9-sensitive linker of the proline-valine-glycine-leucine-isoleucine-glycine (Pro-Val-Gly-Leu-Ile-Gly, PVGLIG) oligopeptide via a convenient and fast liquid-phase synthesis.	Glycine	125-132	matrix metallopeptidase 9	Mus musculus	80-85
32790119-3	2020	Autosomal recessive pathogenic variants in the mitochondrial glycine transporter SLC25A38 have been implicated in a subset of patients with CSA.	Glycine	61-68	solute carrier family 25 member 38	Homo sapiens	81-89
32263314-3	2016	To this end, we prepared and characterized the matrix metalloprotease-2 (MMP-2)/MMP-9-sensitive linker of the proline-valine-glycine-leucine-isoleucine-glycine (Pro-Val-Gly-Leu-Ile-Gly, PVGLIG) oligopeptide via a convenient and fast liquid-phase synthesis.	Glycine	152-159	matrix metallopeptidase 9	Mus musculus	80-85
26577016-7	2016	Glycine substitution in the GluN1 S2-M4 region significantly decreased glutamate potency of GluN1(A804G)/GluN2A receptors, while GluN1(A804G)/GluN2B receptors exhibited no change in glutamate sensitivity.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	142-148
27029941-0	2016	Glycine Regulates Expression and Distribution of Claudin-7 and ZO-3 Proteins in Intestinal Porcine Epithelial Cells.	Glycine	0-7	claudin 7	Homo sapiens	49-58
27029941-12	2016	A glycine concentration of 0.25 mmol/L sustained the localization of claudin-7 and ZO-3 to the interface between enterocytes.	Glycine	2-9	claudin 7	Homo sapiens	69-78
27029941-13	2016	Interestingly, 1 mmol glycine/L promoted the distribution of claudin-4 and claudin-7 to the cytosol and nucleus, and the localization of ZO-3 to the plasma membranes, while decreasing the distribution of ZO-1 at cell-cell contact sites, compared with control cells.	Glycine	22-29	claudin 7	Homo sapiens	75-84
27029941-14	2016	CONCLUSION: Physiologic concentrations of glycine support intestinal mucosal barrier function by regulating the abundance and distribution of claudin-7 and ZO-3 in enterocytes.	Glycine	42-49	claudin 7	Homo sapiens	142-151
27143268-12	2016	The high prevalence of specific IgE to Mal d 1 and Gly m 4 among Bet v 1-sensitized patients indicates that pollen-food allergy syndrome could be of clinical relevance in China.	Glycine	51-54	delta/notch like EGF repeat containing	Homo sapiens	65-68
26692170-6	2016	Two mutations in CYB5D2, the substitutions of arginine (R) 7 with either proline (P) or glycine (G), were reported in colon cancer.	Glycine	88-95	cytochrome b5 domain containing 2	Homo sapiens	17-23
26938218-5	2016	METHODS AND RESULTS: A genome wide association study identified SNPs associated with plasma glycine levels within the CPS1 (Carbamoyl-Phosphate Synthase 1) gene (rs10206976, p-value = 4.709e-11 and rs12613336, p-value = 1.368e-08).	Glycine	92-99	carbamoyl-phosphate synthase 1	Homo sapiens	118-122
26938218-5	2016	METHODS AND RESULTS: A genome wide association study identified SNPs associated with plasma glycine levels within the CPS1 (Carbamoyl-Phosphate Synthase 1) gene (rs10206976, p-value = 4.709e-11 and rs12613336, p-value = 1.368e-08).	Glycine	92-99	carbamoyl-phosphate synthase 1	Homo sapiens	124-154
27241643-8	2016	A G&gt;A substitution at nucleotide 1243 in exon 8 that changes glycine (GGT) to serine (AGT) was observed in most of our patients.	Glycine	64-71	gamma-glutamyltransferase light chain 5 pseudogene	Homo sapiens	73-76
26642840-5	2016	The addition of osmolytes, such as glycine and proline, partially reactivated the Cd2+-mediated inactive PSCKM.	Glycine	35-42	T-cell surface antigen CD2	Pelodiscus sinensis	82-85
26821380-7	2016	The data were consistent with Hem25 not being the sole mitochondrial glycine importer, and we identify a second SLC25 family member Ymc1, as a potential secondary mitochondrial glycine importer.	Glycine	177-184	organic acid transporter	Saccharomyces cerevisiae S288C	132-136
26821380-11	2016	Given the tolerability of glycine and folate in humans, this study points to a potential novel treatment for SLC25A38 congenital sideroblastic anemia.	Glycine	26-33	solute carrier family 25 member 38	Homo sapiens	109-117
27941311-5	2016	METHODS: cRNA encoding PEPT1 or PEPT2 was injected into Xenopus laevis oocytes and glycine-glycine (2 mM)-induced inward current (IGly) taken as measure of glycine-glycine transport.	Glycine	83-90	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	23-28
27941311-5	2016	METHODS: cRNA encoding PEPT1 or PEPT2 was injected into Xenopus laevis oocytes and glycine-glycine (2 mM)-induced inward current (IGly) taken as measure of glycine-glycine transport.	Glycine	91-98	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	23-28
26864036-12	2016	Hence, UCP2/K177E and UCP2/G174L produced the functional incompetence of the glycine-rich motif 1.	Glycine	77-84	uncoupling protein 2	Homo sapiens	7-11
26864036-12	2016	Hence, UCP2/K177E and UCP2/G174L produced the functional incompetence of the glycine-rich motif 1.	Glycine	77-84	uncoupling protein 2	Homo sapiens	22-26
26511319-1	2015	5-Aminolevulinate synthase (ALAS) catalyzes the first step in mammalian heme biosynthesis, the pyridoxal 5"-phosphate (PLP)-dependent and reversible reaction between glycine and succinyl-CoA to generate CoA, CO2, and 5-aminolevulinate (ALA).	Glycine	166-173	pyridoxal phosphatase	Homo sapiens	119-122
26657009-7	2015	The antibodies were found to be reactive with a central Cit-Gly motif being essential for ACPA reactivity and to be cross-reactive between the selected citrullinated peptides.	Glycine	60-63	proteinase 3	Homo sapiens	90-94
26593911-6	2015	The ectopic expression of SBP1(GLY) also caused mitochondrial damage in HCT116 cells.	Glycine	31-34	selenium binding protein 1	Homo sapiens	26-30
26605136-1	2015	5-Aminolevulinate synthase (ALAS) catalyzes the initial step of mammalian heme biosynthesis, the condensation between glycine and succinyl-CoA to produce CoA, CO2, and 5-aminolevulinate.	Glycine	118-125	5'-aminolevulinate synthase 2	Homo sapiens	28-32
28455045-2	2015	Reducing sugars, xylose, ribose, fructose, glucose, and non-reducing sucrose were reacted with glycine (Xyl-Gly, Rib-Gly, Fru-Gly, Glc-Gly, and Suc-Gly), or lysine (Xyl-Lys, Rib-Lys, Fru-Lys, Glc-Lys, and Suc-Lys), respectively, at temperatures of 150 C and 180 C for time periods ranging from 5 to 60min.	Glycine	95-102	zinc finger and BTB domain containing 22	Homo sapiens	122-125
28455045-2	2015	Reducing sugars, xylose, ribose, fructose, glucose, and non-reducing sucrose were reacted with glycine (Xyl-Gly, Rib-Gly, Fru-Gly, Glc-Gly, and Suc-Gly), or lysine (Xyl-Lys, Rib-Lys, Fru-Lys, Glc-Lys, and Suc-Lys), respectively, at temperatures of 150 C and 180 C for time periods ranging from 5 to 60min.	Glycine	95-102	zinc finger and BTB domain containing 22	Homo sapiens	183-186
26082520-2	2015	The adaptor protein CD2BP2, originally identified as a binding partner of the adhesion molecule CD2, is a pre-spliceosomal assembly factor that utilizes its glycine-tyrosine-phenylalanine (GYF) domain to co-localize with spliceosomal proteins.	Glycine	157-164	CD2 antigen	Mus musculus	20-23
26059756-3	2015	GSH is synthesized from glutamic acid, cysteine, and glycine via two sequential ATP-consuming steps, which are catalyzed by glutamate cysteine ligase (GCL) and GSH synthetase (GSS).	Glycine	53-60	glutamate-cysteine ligase catalytic subunit	Homo sapiens	151-154
26071957-5	2015	The NMDA-receptor (NMDA-R) antagonists ketamine and MK-801 (10nM) counteracted the NMDA/glycine-induced reduction in neurite outgrowth and the neuronal NO synthase (nNOS) inhibitor 1-[2-(trifluoromethyl)phenyl] imidazole (TRIM) (100nM) counteracted both the NMDA/glycine and l-arginine-induced decreases in neurite outgrowth.	Glycine	88-95	nitric oxide synthase 1	Homo sapiens	165-169
25999474-4	2015	Phg1A, as well as its human ortholog TM9SF4 specifically associated with glycine-rich TMDs.	Glycine	73-80	transmembrane 9 superfamily member 4	Homo sapiens	37-43
25999474-5	2015	In human cells, genetic inactivation of TM9SF4 resulted in an increased retention of glycine-rich TMDs in the endoplasmic reticulum, whereas TM9SF4 overexpression enhanced their surface localization.	Glycine	85-92	transmembrane 9 superfamily member 4	Homo sapiens	40-46
25999474-6	2015	The bulk of the TM9SF4 protein was localized in the Golgi complex and a proximity-ligation assay suggested that it might interact with glycine-rich TMDs.	Glycine	135-142	transmembrane 9 superfamily member 4	Homo sapiens	16-22
25955210-5	2015	Both transmembrane segments of Mic10 carry a characteristic four-glycine motif, which has been found in the ring-forming rotor subunit of F1Fo-ATP synthases.	Glycine	65-72	mitochondrial contact site and cristae organizing system subunit 10	Homo sapiens	31-36
25955210-7	2015	The four-glycine motifs are dispensable for interaction of Mic10 with other MICOS subunits but are crucial for the formation of large Mic10 oligomers.	Glycine	9-16	mitochondrial contact site and cristae organizing system subunit 10	Homo sapiens	134-139
25955211-5	2015	We show that Mic10 spans the inner membrane in a hairpin topology and that its ability to sculpt membranes depends on oligomerization through a glycine-rich motif.	Glycine	144-151	Mic10p	Saccharomyces cerevisiae S288C	13-18
27803322-7	2016	Emphasizing the similarity with Nef, we show that S2 is myristoylated, and, as is compatible with a crucial role in posttranslational modification, its N-terminal glycine is required for anti-SERINC5 activity.	Glycine	163-170	serine incorporator 5	Homo sapiens	192-199
27481395-1	2016	Glycine cleavage system (GCS) catalyzes the degradation of glycine and disruption of its components encoded by GLDC, AMT and GCSH are the only known causes of glycine encephalopathy, also known as non-ketotic hyperglycinemia (NKH).	Glycine	0-7	glycine decarboxylase	Homo sapiens	111-115
27481395-1	2016	Glycine cleavage system (GCS) catalyzes the degradation of glycine and disruption of its components encoded by GLDC, AMT and GCSH are the only known causes of glycine encephalopathy, also known as non-ketotic hyperglycinemia (NKH).	Glycine	0-7	glycine cleavage system protein H	Homo sapiens	125-129
27481395-1	2016	Glycine cleavage system (GCS) catalyzes the degradation of glycine and disruption of its components encoded by GLDC, AMT and GCSH are the only known causes of glycine encephalopathy, also known as non-ketotic hyperglycinemia (NKH).	Glycine	159-166	glycine decarboxylase	Homo sapiens	111-115
27481395-1	2016	Glycine cleavage system (GCS) catalyzes the degradation of glycine and disruption of its components encoded by GLDC, AMT and GCSH are the only known causes of glycine encephalopathy, also known as non-ketotic hyperglycinemia (NKH).	Glycine	159-166	glycine cleavage system protein H	Homo sapiens	125-129
28361593-2	2016	The following is the first report of a double heterozygosity for Hb Q-Thailand [alpha74(EF3)Asp His; HBA1: c.223G&gt;C] with alpha+-thalassemia (alpha+-thal) and Hb J-Bangkok [beta56(D7)Gly Asp; HBB: c.170G&gt;A] found in a Chinese family.	Glycine	186-189	hemoglobin subunit alpha 1	Homo sapiens	101-105
27759100-1	2016	SLC7A10 (Asc-1) is a sodium-independent amino acid transporter known to facilitate transport of a number of amino acids including glycine, L-serine, L-alanine, and L-cysteine, as well as their D-enantiomers.	Glycine	130-137	solute carrier family 7 member 10	Homo sapiens	0-7
27759100-1	2016	SLC7A10 (Asc-1) is a sodium-independent amino acid transporter known to facilitate transport of a number of amino acids including glycine, L-serine, L-alanine, and L-cysteine, as well as their D-enantiomers.	Glycine	130-137	solute carrier family 7 member 10	Homo sapiens	9-14
27296112-7	2016	In silico analysis revealed that a new nNOS-specific GSP (glycine-serine-proline) motif was well-conserved across species at nNOS-Ser(293), which is located ahead of the N-terminal hook.	Glycine	58-65	nitric oxide synthase 1, neuronal	Mus musculus	39-43
27296112-7	2016	In silico analysis revealed that a new nNOS-specific GSP (glycine-serine-proline) motif was well-conserved across species at nNOS-Ser(293), which is located ahead of the N-terminal hook.	Glycine	58-65	nitric oxide synthase 1, neuronal	Mus musculus	125-129
27473325-1	2016	PURPOSE: Approximately 70 % of triple-negative breast cancer (TNBC) cell lines are identified to upregulate phosphoglycerate dehydrogenase (PHGDH), which regulates the intracellular synthesis of serine and glycine, and promotes tumor growth.	Glycine	206-213	phosphoglycerate dehydrogenase	Homo sapiens	108-138
27473325-1	2016	PURPOSE: Approximately 70 % of triple-negative breast cancer (TNBC) cell lines are identified to upregulate phosphoglycerate dehydrogenase (PHGDH), which regulates the intracellular synthesis of serine and glycine, and promotes tumor growth.	Glycine	206-213	phosphoglycerate dehydrogenase	Homo sapiens	140-145
27240952-1	2016	Ubiquitin-fold modifier 1 (Ufm1) specific protease (UfSP) is a novel cysteine protease that activates Ufm1 from its precursor by processing the C-terminus to expose the conserved Gly necessary for substrate conjugation and de-conjugates Ufm1 from the substrate.	Glycine	179-182	Ubiquitin-fold modifier 1	Caenorhabditis elegans	0-25
27240952-1	2016	Ubiquitin-fold modifier 1 (Ufm1) specific protease (UfSP) is a novel cysteine protease that activates Ufm1 from its precursor by processing the C-terminus to expose the conserved Gly necessary for substrate conjugation and de-conjugates Ufm1 from the substrate.	Glycine	179-182	Ubiquitin-fold modifier 1	Caenorhabditis elegans	27-31
27240952-1	2016	Ubiquitin-fold modifier 1 (Ufm1) specific protease (UfSP) is a novel cysteine protease that activates Ufm1 from its precursor by processing the C-terminus to expose the conserved Gly necessary for substrate conjugation and de-conjugates Ufm1 from the substrate.	Glycine	179-182	Ubiquitin-fold modifier 1	Caenorhabditis elegans	102-106
27240952-1	2016	Ubiquitin-fold modifier 1 (Ufm1) specific protease (UfSP) is a novel cysteine protease that activates Ufm1 from its precursor by processing the C-terminus to expose the conserved Gly necessary for substrate conjugation and de-conjugates Ufm1 from the substrate.	Glycine	179-182	Ubiquitin-fold modifier 1	Caenorhabditis elegans	102-106
27225947-10	2016	Moreover, glycine resulted in decreased mRNA expresson of Toll-like receptor 4 (TLR4), nucleotide-binding oligomerization domain protein 2 (NOD2), and their respective downstream molecules in gastrocnemius or LD muscles.	Glycine	10-17	nucleotide binding oligomerization domain containing 2	Homo sapiens	87-138
27225947-10	2016	Moreover, glycine resulted in decreased mRNA expresson of Toll-like receptor 4 (TLR4), nucleotide-binding oligomerization domain protein 2 (NOD2), and their respective downstream molecules in gastrocnemius or LD muscles.	Glycine	10-17	nucleotide binding oligomerization domain containing 2	Homo sapiens	140-144
27225947-12	2016	The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.	Glycine	24-31	nucleotide binding oligomerization domain containing 2	Homo sapiens	157-161
27187177-4	2016	The acute (6 h) and chronic (11 d) proliferative responses to long-acting human (Gly(2))GLP-2 in the crypt TA zone, but not in the active or reserve stem cell zones, were both impaired by Bmi-1 haploinsufficiency.	Glycine	81-84	BMI1 proto-oncogene, polycomb ring finger	Homo sapiens	188-193
27230263-1	2016	Bile acid CoA:amino acid N-acyltransferase (BAAT) is the terminal enzyme in the synthesis of bile salts from cholesterol and catalyzes the conjugation of taurine or glycine to bile acid CoA thioesters to form bile acid N-acylamidates.	Glycine	165-172	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	0-42
27230263-1	2016	Bile acid CoA:amino acid N-acyltransferase (BAAT) is the terminal enzyme in the synthesis of bile salts from cholesterol and catalyzes the conjugation of taurine or glycine to bile acid CoA thioesters to form bile acid N-acylamidates.	Glycine	165-172	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	44-48
27039337-0	2016	Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2.	Glycine	36-39	nucleotide binding oligomerization domain containing 2	Homo sapiens	105-109
27039337-4	2016	We have investigated how minor modifications of hit compound acyl Gly-L-Ala-D-Glu derivative I modulate the molecular recognition by NOD2.	Glycine	66-69	nucleotide binding oligomerization domain containing 2	Homo sapiens	133-137
27264869-4	2016	MDM2 recruitment to chromatin is a tightly regulated process that occurs during oxidative stress and serine/glycine deprivation and is modulated by the pyruvate kinase M2 (PKM2) metabolic enzyme.	Glycine	108-115	pyruvate kinase, muscle	Mus musculus	172-176
27010645-5	2016	KEY RESULTS: Six pairs of positions in GluN1/GluN2B significantly interacted to regulate ethanol inhibition: Gly(638) /Met(824) , Gly(638) /Leu(825) , Phe(639) /Leu(825) , Phe(639) /Gly(826) , Met(818) /Phe(637) and Val(820) /Phe(637) .	Glycine	109-112	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	45-51
27010645-5	2016	KEY RESULTS: Six pairs of positions in GluN1/GluN2B significantly interacted to regulate ethanol inhibition: Gly(638) /Met(824) , Gly(638) /Leu(825) , Phe(639) /Leu(825) , Phe(639) /Gly(826) , Met(818) /Phe(637) and Val(820) /Phe(637) .	Glycine	130-133	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	45-51
27010645-5	2016	KEY RESULTS: Six pairs of positions in GluN1/GluN2B significantly interacted to regulate ethanol inhibition: Gly(638) /Met(824) , Gly(638) /Leu(825) , Phe(639) /Leu(825) , Phe(639) /Gly(826) , Met(818) /Phe(637) and Val(820) /Phe(637) .	Glycine	130-133	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	45-51
32995773-3	2021	We then identified the heptad repeat 2 (HR2) stalk as a major cause of spike metastability, designed an HR2-deleted glycine-capped spike (S2GDeltaHR2), and displayed S2GDeltaHR2 on three SApNPs with high yield, purity, and antigenicity.	Glycine	116-123	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	71-76
27162334-2	2016	A photoreceptor specific ORF15 variant of RPGR (RPGR(ORF15)), carrying multiple Glu-Gly tandem repeats and a C-terminal basic domain of unknown function, localizes to the connecting cilium where it is thought to regulate cargo trafficking.	Glycine	84-87	retinitis pigmentosa GTPase regulator	Mus musculus	42-46
27162334-2	2016	A photoreceptor specific ORF15 variant of RPGR (RPGR(ORF15)), carrying multiple Glu-Gly tandem repeats and a C-terminal basic domain of unknown function, localizes to the connecting cilium where it is thought to regulate cargo trafficking.	Glycine	84-87	retinitis pigmentosa GTPase regulator	Mus musculus	48-59
27162334-3	2016	Here we show that tubulin tyrosine ligase like-5 (TTLL5) glutamylates RPGR(ORF15) in its Glu-Gly-rich repetitive region containing motifs homologous to the alpha-tubulin C-terminal tail.	Glycine	93-96	retinitis pigmentosa GTPase regulator	Mus musculus	70-80
26662804-3	2016	ATG4B, a cysteine protease required for autophagy, cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine which is necessary for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to autophagosome precursor membranes.	Glycine	132-139	autophagy related 4B cysteine peptidase	Homo sapiens	0-5
32995773-3	2021	We then identified the heptad repeat 2 (HR2) stalk as a major cause of spike metastability, designed an HR2-deleted glycine-capped spike (S2GDeltaHR2), and displayed S2GDeltaHR2 on three SApNPs with high yield, purity, and antigenicity.	Glycine	116-123	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	131-136
33029096-1	2020	Guanidinoacetic acid (GAA, also known as glycocyamine or betacyamine) is a naturally-occurring derivative of glycine and a direct metabolic precursor of creatine, a key player in high-phosphate cellular bioenergetics.	Glycine	109-116	alpha glucosidase	Homo sapiens	22-25
26851771-6	2016	In the second postnatal week the forskolin-induced increase of miniature inhibitory postsynaptic potential (mIPSC) frequency was significantly larger in control as compared to Glra3 knockout mice suggesting that presynaptic glycine release in the hypoglossal nucleus is partially depending on GlyR alpha3.	Glycine	224-231	glycine receptor, alpha 3 subunit	Mus musculus	176-181
32571778-0	2020	Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.	Glycine	33-40	phosphoglycerate dehydrogenase	Homo sapiens	80-85
26941104-3	2016	The mutational hotspot in RPGR(ORF15)is an unusual C-terminal domain encoded by exon ORF15, which is rich in polyglutamates and glycine residues (Glu-Gly domain) followed by a short stretch of basic amino acid residues (RPGR(C2)domain; residues 1072-1152).	Glycine	128-135	retinitis pigmentosa GTPase regulator	Mus musculus	26-36
26941104-3	2016	The mutational hotspot in RPGR(ORF15)is an unusual C-terminal domain encoded by exon ORF15, which is rich in polyglutamates and glycine residues (Glu-Gly domain) followed by a short stretch of basic amino acid residues (RPGR(C2)domain; residues 1072-1152).	Glycine	150-153	retinitis pigmentosa GTPase regulator	Mus musculus	26-36
26941104-7	2016	Our results indicate that RPGR(ORF15)is posttranslationally glutamylated in the Glu-Gly domain and that the GT335 antibody predominantly recognizes RPGR(ORF15)in photoreceptor cilia.	Glycine	84-87	retinitis pigmentosa GTPase regulator	Mus musculus	26-36
32640336-7	2020	Also, GBH and Gly downregulated Hoxa10 and Lif genes, with no difference in Muc1 and Areg expression.	Glycine	14-17	homeobox A10	Rattus norvegicus	32-38
27143876-4	2016	Upon cleavage of the amide bond between Leu and Gly in the Pep-FITC by protease-MMP2, the FITC bound to nrGO was separated from nrGO surface, disrupting the fluorescence resonance energy transfer process and resulting in fluorescence recovery of FITC.	Glycine	48-51	matrix metallopeptidase 2	Homo sapiens	80-84
26963408-7	2016	Motifs that included sequential proline and glycine showed a CDR3 length independent distribution and examining codon usage indicates that a large proportion of these can be explained by P-nucleotide addition from the 5" end of the D region.	Glycine	44-51	CDR3	Homo sapiens	61-65
26563333-8	2016	Glycine induced the up-regulation of estrogen receptor-beta mRNA expression and estrogen-response element-luciferase activity in MG-63 and MCF-7 cells.	Glycine	0-7	estrogen receptor 2	Homo sapiens	37-59
32344286-2	2020	In this paper, we have proposed that guanidinoacetase, an enzyme present in healthy gut microbiota, might contribute to gross GAA turnover by hydrolyzing GAA to glycine and urea or vice versa.	Glycine	161-168	alpha glucosidase	Homo sapiens	126-129
26840079-5	2016	MATERIALS AND METHODS: Germline DNA from neuroblastoma patients and matched controls was assessed for the FGFR4 Gly/Arg388 polymorphism by RT-PCR.	Glycine	112-115	fibroblast growth factor receptor 4	Homo sapiens	106-111
32344286-2	2020	In this paper, we have proposed that guanidinoacetase, an enzyme present in healthy gut microbiota, might contribute to gross GAA turnover by hydrolyzing GAA to glycine and urea or vice versa.	Glycine	161-168	alpha glucosidase	Homo sapiens	154-157
32049370-2	2020	We found a novel frameshift trucation mutation c.1596_1597insAT, p. Gly533Metfs*82 in exon7 (V2 tail domian) of KRT1, which replacing the glycine-serine-rich tail of KRT1 with the alanine-rich 75 amino acids, developed a mild IHCM phenotype.	Glycine	138-152	keratin 1	Homo sapiens	112-116
26941605-1	2016	D-serine is an endogenous coagonist at the glycine site of synaptic NMDA receptors (NMDARs), synthesized by serine racemase (SR) through conversion of L-serine.	Glycine	43-50	serine racemase	Homo sapiens	108-123
26941605-1	2016	D-serine is an endogenous coagonist at the glycine site of synaptic NMDA receptors (NMDARs), synthesized by serine racemase (SR) through conversion of L-serine.	Glycine	43-50	serine racemase	Homo sapiens	125-127
32049370-2	2020	We found a novel frameshift trucation mutation c.1596_1597insAT, p. Gly533Metfs*82 in exon7 (V2 tail domian) of KRT1, which replacing the glycine-serine-rich tail of KRT1 with the alanine-rich 75 amino acids, developed a mild IHCM phenotype.	Glycine	138-152	keratin 1	Homo sapiens	166-170
32330411-4	2020	In situ quantification of neurotransmitters in the brains of PYCR2 mutant mice and patients revealed a signature of encephalopathy driven by excessive cerebral glycine.	Glycine	160-167	pyrroline-5-carboxylate reductase family, member 2	Mus musculus	61-66
26478928-7	2015	NRG1 retrodialysis (10 nM) reduced extracellular glutamate and glycine levels in the prefrontal cortex and hippocampus, and prevented PCP-induced increase in extracellular GABA levels in the hippocampus.	Glycine	63-70	neuregulin 1	Mus musculus	0-4
26478928-9	2015	Furthermore, the ability of NRG1 treatment to alter GABA, glutamate, and glycine levels in the presence of PCP also suggests that NRG1 signaling has the potential to alter disrupted neurotransmission in patients with schizophrenia.	Glycine	73-80	neuregulin 1	Homo sapiens	28-32
26478928-9	2015	Furthermore, the ability of NRG1 treatment to alter GABA, glutamate, and glycine levels in the presence of PCP also suggests that NRG1 signaling has the potential to alter disrupted neurotransmission in patients with schizophrenia.	Glycine	73-80	neuregulin 1	Homo sapiens	130-134
32055850-5	2020	Glycine and 2HG concentrations as measured by MRS were correlated with tumor cell proliferation (MIB-1 labeling index), expression of mitochondrial serine hydroxymethyltransferase (SHMT2) and glycine decarboxylase (GLDC) enzymes, and patient overall survival.	Glycine	0-7	glycine decarboxylase	Homo sapiens	192-213
25908846-6	2015	We found that heterodimer dissociation is an energy-independent process that takes place through a disruption of the alpha-tubulin-beta-tubulin interface that is caused by a steric interaction between beta-tubulin and the TBCE cytoskeleton-associated protein glycine-rich (CAP-Gly) and leucine-rich repeat (LRR) domains.	Glycine	259-266	tubulin folding cofactor E	Homo sapiens	222-226
25908846-6	2015	We found that heterodimer dissociation is an energy-independent process that takes place through a disruption of the alpha-tubulin-beta-tubulin interface that is caused by a steric interaction between beta-tubulin and the TBCE cytoskeleton-associated protein glycine-rich (CAP-Gly) and leucine-rich repeat (LRR) domains.	Glycine	277-280	tubulin folding cofactor E	Homo sapiens	222-226
32055850-10	2020	GLDC and SHMT2 expression were detectable in all tumors with glycine concentration, demonstrating an inverse correlation with GLDC.	Glycine	61-68	glycine decarboxylase	Homo sapiens	0-4
32224253-1	2020	A combination of small angle X-ray scattering (SAXS) and molecular dynamics (MD) simulations based on a coarse grained model is used to examine the effect of glycine substitutions in the short connector between the SH3 and SH2 domains of Hck, a member of the Src-family kinases.	Glycine	158-165	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	238-241
25855294-5	2015	GLDC inhibition impairs cells with high SHMT2 levels as the excess glycine not metabolized by GLDC can be converted to the toxic molecules aminoacetone and methylglyoxal.	Glycine	67-74	glycine decarboxylase	Homo sapiens	0-4
32224253-2	2020	It has been shown previously that the activity of cSrc kinase is upregulated by substitution of 3 residues by glycine in the SH3-SH2 connector.	Glycine	110-117	C-terminal Src kinase	Homo sapiens	50-61
32224253-3	2020	Here, analysis of SAXS data indicates that the population of Hck in the disassembled state increases from 25% in the wild type kinase to 76% in the glycine mutant.	Glycine	148-155	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	61-64
32606761-2	2020	Phosphoserine aminotransferase 1 (PSAT1) catalyzes the second step of the serine-glycine biosynthesis pathway; the effects and mechanism of PSAT1 in epithelial ovarian cancer (EOC) remains unclear.	Glycine	81-88	phosphoserine aminotransferase 1	Homo sapiens	0-32
25687964-8	2015	Thus, restoration of Sis1 in vitro activity suggests that intramolecular interactions between the J-domain and glycine-rich region control co-chaperone activity, which is optimal only when Sis1 interacts with the EEVD(Hsp70) motif.	Glycine	111-118	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	21-25
25687964-8	2015	Thus, restoration of Sis1 in vitro activity suggests that intramolecular interactions between the J-domain and glycine-rich region control co-chaperone activity, which is optimal only when Sis1 interacts with the EEVD(Hsp70) motif.	Glycine	111-118	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	189-193
32606761-2	2020	Phosphoserine aminotransferase 1 (PSAT1) catalyzes the second step of the serine-glycine biosynthesis pathway; the effects and mechanism of PSAT1 in epithelial ovarian cancer (EOC) remains unclear.	Glycine	81-88	phosphoserine aminotransferase 1	Homo sapiens	34-39
24905386-8	2015	HbA2-Tunis [delta46(CD5), Gly   Glu, GGG   GAG] is the newly described delta-chain variant in our laboratory, and some other variants (Hb Constant Spring, G San Jose, and Hb J-Bangkok) are very uncommon in the Mediterranean region.	Glycine	26-29	hemoglobin subunit alpha 2	Homo sapiens	0-4
32347002-0	2020	Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.	Glycine	32-39	C9orf72-SMCR8 complex subunit	Homo sapiens	62-69
25761142-0	2015	A glycine insertion in the estrogen-related receptor (ERR) is associated with enhanced expression of three cytochrome P450 genes in transgenic Drosophila melanogaster.	Glycine	2-9	estrogen-related receptor	Drosophila melanogaster	27-52
25761142-0	2015	A glycine insertion in the estrogen-related receptor (ERR) is associated with enhanced expression of three cytochrome P450 genes in transgenic Drosophila melanogaster.	Glycine	2-9	estrogen-related receptor	Drosophila melanogaster	54-57
25761142-5	2015	Sequencing of ERRa and ERRb in select DDT susceptible and resistant D. melanogaster strains has revealed a glycine (G) codon insertion which was only observed in the ligand binding domain of ERR from the resistant strains tested (ERR-G).	Glycine	107-114	estrogen-related receptor	Drosophila melanogaster	14-17
25761142-5	2015	Sequencing of ERRa and ERRb in select DDT susceptible and resistant D. melanogaster strains has revealed a glycine (G) codon insertion which was only observed in the ligand binding domain of ERR from the resistant strains tested (ERR-G).	Glycine	107-114	estrogen-related receptor	Drosophila melanogaster	23-26
32066088-5	2020	Anti-CysC antibodies were immobilized on the IDE by covalent entrapment via ethylenediamine bifunctional agent, followed by glycine blocking in acid and alkaline medium.	Glycine	124-131	cystatin C	Homo sapiens	5-9
32194228-5	2020	In the present study, we found that phosphorylation level of GluN2B at tyrosine 1472 was modulated by F&R-induced LTP but not by glycine-induced LTP in hippocampal slices.	Glycine	129-136	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	61-67
25572393-5	2015	Put4p-mimicking substitutions in TMS3 (S130C), TMS6 (F252L, S253G), TMS8 (W351F), and TMS10 (T414S) broadened the specificity of PrnB, enabling it to recognize more efficiently l-alanine, l-azetidine-2-carboxylic acid, and glycine without significantly affecting the apparent Km for l-proline.	Glycine	223-230	proline permease PUT4	Saccharomyces cerevisiae S288C	0-5
25572393-7	2015	A combination of all five Put4p-ressembling substitutions resulted in a functional allele that could also transport l-alanine and glycine, displaying a specificity profile impressively similar to that of Put4p.	Glycine	130-137	proline permease PUT4	Saccharomyces cerevisiae S288C	26-31
25572393-7	2015	A combination of all five Put4p-ressembling substitutions resulted in a functional allele that could also transport l-alanine and glycine, displaying a specificity profile impressively similar to that of Put4p.	Glycine	130-137	proline permease PUT4	Saccharomyces cerevisiae S288C	204-209
31823667-6	2020	Among them, the upregulated Bcl-associated X protein was related to "apoptosis," while the downregulated 5"-aminolevulinate synthase 2 (ALAS2) was related to both "glycine, serine, and threonine metabolism" and "porphyrin and chlorophyll metabolism" in pathway enrichment analysis.	Glycine	164-171	5'-aminolevulinate synthase 2	Homo sapiens	105-134
25837937-7	2015	Therefore, GT-0198 is considered to exhibit its analgesic effect via the activation of a glycine receptor by glycine following presynaptic GlyT2 inhibition in the spinal cord.	Glycine	89-96	solute carrier family 6 member 5	Homo sapiens	139-144
31823667-6	2020	Among them, the upregulated Bcl-associated X protein was related to "apoptosis," while the downregulated 5"-aminolevulinate synthase 2 (ALAS2) was related to both "glycine, serine, and threonine metabolism" and "porphyrin and chlorophyll metabolism" in pathway enrichment analysis.	Glycine	164-171	5'-aminolevulinate synthase 2	Homo sapiens	136-141
31919735-0	2020	Correction to: Phosphomimetic Mutation of Glycine Transporter GlyT1 C-Terminal PDZ Binding Motif Inhibits its Interactions with PSD95.	Glycine	42-49	discs large MAGUK scaffold protein 4	Homo sapiens	128-133
25490467-6	2015	RESULTS: We demonstrate that the C-terminal part of Vif interacts directly with LC3B, independently of the presence of APOBEC3G.Vif binds to pro-LC3 and autophagy-related protein 4-cleaved LC3 forms, and glycine 120, the amino acid conjugated to phosphatidylethanolamine on autophagosomes, is required.	Glycine	204-211	microtubule associated protein 1 light chain 3 beta	Homo sapiens	80-84
31932327-0	2020	Glycine lipids of Porphyromonas gingivalis are agonists for Toll-like receptor 2.	Glycine	0-7	toll-like receptor 2	Mus musculus	60-80
31932327-2	2020	Both serine-glycine lipid classes were previously shown to engage human and mouse Toll-like receptor 2 (TLR2) and to inhibit mouse osteoblast differentiation and function through engagement of TLR2.	Glycine	5-19	toll-like receptor 2	Mus musculus	82-102
31932327-2	2020	Both serine-glycine lipid classes were previously shown to engage human and mouse Toll-like receptor 2 (TLR2) and to inhibit mouse osteoblast differentiation and function through engagement of TLR2.	Glycine	5-19	toll-like receptor 2	Mus musculus	104-108
25123937-0	2015	Complex formation of Sn(II) with glycine: an IR, DTA/TGA and DFT investigation.	Glycine	33-40	T-box transcription factor 1	Homo sapiens	53-56
31932327-2	2020	Both serine-glycine lipid classes were previously shown to engage human and mouse Toll-like receptor 2 (TLR2) and to inhibit mouse osteoblast differentiation and function through engagement of TLR2.	Glycine	5-19	toll-like receptor 2	Mus musculus	193-197
32498570-0	2020	Severe alpha-Thalassemia Due to Compound Heterozygosity for Hb Adana (alpha59 Gly>Asp) (HBA1: c.179G > A) and Codon 127 (A > T) (HBA2: c.382A > T) in an Iranian Family.	Glycine	78-81	hemoglobin subunit alpha 1	Homo sapiens	88-92
25729929-4	2015	G553A mutation was found in the MASP-2 gene that led to the substitution of glycine with serine.	Glycine	76-83	MBL associated serine protease 2	Bos taurus	32-38
31376158-8	2020	Although NMDAR-dependent, NYX-2925-mediated colocalization of GluN2B with PSD-95 occurred independent of ion flux, as colocalization increased in the presence of either the NMDAR channel blocker (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate or glycine site antagonist 7-chlorokynurenic acid.	Glycine	289-296	nyctalopin	Rattus norvegicus	26-29
25218309-1	2015	The synthetic 15-mer arginine-glycine-aspartic acid (RGD) domain of osteopontin (OPN) is protective in vitro and in vivo against dopaminergic cell death and this protective effect may be mediated through interaction with integrin receptors to regulate neurotrophic factor levels.	Glycine	30-37	secreted phosphoprotein 1	Rattus norvegicus	68-79
25218309-1	2015	The synthetic 15-mer arginine-glycine-aspartic acid (RGD) domain of osteopontin (OPN) is protective in vitro and in vivo against dopaminergic cell death and this protective effect may be mediated through interaction with integrin receptors to regulate neurotrophic factor levels.	Glycine	30-37	secreted phosphoprotein 1	Rattus norvegicus	81-84
31376158-8	2020	Although NMDAR-dependent, NYX-2925-mediated colocalization of GluN2B with PSD-95 occurred independent of ion flux, as colocalization increased in the presence of either the NMDAR channel blocker (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate or glycine site antagonist 7-chlorokynurenic acid.	Glycine	289-296	discs large MAGUK scaffold protein 4	Rattus norvegicus	74-80
31929360-4	2020	METHODS: Sema3A and HIF1alpha were linked together with the three (GGGGS; G, glycine; S, serine) peptide fragment, and their co-expression in iPSC-MSCs was mediated by a lentiviral vector.	Glycine	77-84	semaphorin 3A	Homo sapiens	9-15
31885210-4	2020	Significant higher OPN expression is found in foam cells along with the aggravating capacity of macrophage recruitment due to its arginine-glycine-aspartate sequence and interaction with CD44.	Glycine	139-146	secreted phosphoprotein 1	Mus musculus	19-22
25315779-2	2014	After synaptic vesicle fusion, glycine is recovered back to the presynaptic terminal by the neuronal glycine transporter 2 (GlyT2) to maintain quantal glycine content in synaptic vesicles.	Glycine	31-38	solute carrier family 6 member 5	Homo sapiens	101-122
32955901-10	2020	Phenylalanine, tyrosine, glycine, lysine, and aspartic acid were found to be the headliner amino acids in the interactions between Arbidol and binding domains of spike glycoproteins in the SARS-CoV2 (Tab.	Glycine	25-32	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	162-167
25315779-2	2014	After synaptic vesicle fusion, glycine is recovered back to the presynaptic terminal by the neuronal glycine transporter 2 (GlyT2) to maintain quantal glycine content in synaptic vesicles.	Glycine	31-38	solute carrier family 6 member 5	Homo sapiens	124-129
25315779-2	2014	After synaptic vesicle fusion, glycine is recovered back to the presynaptic terminal by the neuronal glycine transporter 2 (GlyT2) to maintain quantal glycine content in synaptic vesicles.	Glycine	101-108	solute carrier family 6 member 5	Homo sapiens	124-129
31536722-13	2020	It also showed a higher structural homology and similarity of transmembrane regions of Lhr between both species, in contrast to Fshr, possibly related to the substitution of the conserved cysteine residue in the transmembrane domain 6 in medaka Fshr with glycine.	Glycine	255-262	lutropin-choriogonadotropic hormone receptor	Oryzias latipes	87-90
26592460-4	2016	A single glycine residue located in the BB-loop of the SARM TIR domain, G601, was identified as essential for interaction.	Glycine	9-16	sterile alpha and TIR motif containing 1	Homo sapiens	55-59
32112323-4	2020	Using detergent-purified GlyT1 protein and a tritium-labeled glycine uptake inhibitor small molecule, we find sybody candidates that increase the apparent melting temperature in SPA-TS by several degrees.	Glycine	61-68	surfactant protein A1	Homo sapiens	178-181
26547262-4	2016	METHODS: We investigated, through a combined immunohistochemical and functional approach, whether [Gly(2) ]GLP-2, a GLP-2 analog, was able to counteract the detrimental effects of long-term cisplatin administration in the mucosa and myenteric neurons of mouse gastric fundus.	Glycine	99-102	glucagon-like peptide 2 receptor	Mus musculus	107-112
26547262-4	2016	METHODS: We investigated, through a combined immunohistochemical and functional approach, whether [Gly(2) ]GLP-2, a GLP-2 analog, was able to counteract the detrimental effects of long-term cisplatin administration in the mucosa and myenteric neurons of mouse gastric fundus.	Glycine	99-102	glucagon-like peptide 2 receptor	Mus musculus	116-121
26547262-5	2016	KEY RESULTS: Morphological experiments showed a reduction in the epithelium thickness in cisplatin-treated mice, which was prevented by [Gly(2) ]GLP-2 co-treatment.	Glycine	137-140	glucagon-like peptide 2 receptor	Mus musculus	145-150
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	0-7	glycine cleavage system protein H	Homo sapiens	24-27
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	0-7	glycine decarboxylase	Homo sapiens	221-242
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	0-7	glycine decarboxylase	Homo sapiens	244-248
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	0-7	glycine cleavage system protein H	Homo sapiens	251-284
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	0-7	glycine cleavage system protein H	Homo sapiens	286-290
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	81-88	glycine cleavage system protein H	Homo sapiens	24-27
26547262-6	2016	Immunohistochemistry demonstrated that cisplatin caused a significant decrease in myenteric neurons, mainly those expressing neuronal nitric oxide synthase (nNOS), that was prevented by [Gly(2) ]GLP-2 co-treatment.	Glycine	187-190	nitric oxide synthase 1, neuronal	Mus musculus	125-155
26547262-6	2016	Immunohistochemistry demonstrated that cisplatin caused a significant decrease in myenteric neurons, mainly those expressing neuronal nitric oxide synthase (nNOS), that was prevented by [Gly(2) ]GLP-2 co-treatment.	Glycine	187-190	nitric oxide synthase 1, neuronal	Mus musculus	157-161
26547262-6	2016	Immunohistochemistry demonstrated that cisplatin caused a significant decrease in myenteric neurons, mainly those expressing neuronal nitric oxide synthase (nNOS), that was prevented by [Gly(2) ]GLP-2 co-treatment.	Glycine	187-190	glucagon-like peptide 2 receptor	Mus musculus	195-200
26547262-8	2016	The NO synthesis inhibitor L-N(G) -nitro arginine caused an increase in amplitude of the contractile responses that was greater in preparations from cisplatin+[Gly(2) ]GLP-2 treated mice compared to the cisplatin-treated ones.	Glycine	160-163	glucagon-like peptide 2 receptor	Mus musculus	168-173
25205677-4	2014	Coapplication of 50 muM PYD-106 with a maximally effective concentration of glutamate and glycine increases the response of GluN1/GluN2C NMDA receptors in HEK-293 cells to 221% of that obtained in the absence of PYD (taken as 100%).	Glycine	90-97	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	130-136
31704028-5	2019	When binding to its agonist glycine or D-serine, GluD1 elicits non-ionotropic postsynaptic signaling involving the guanine nucleotide exchange factor ARHGEF12 and the regulatory subunit of protein phosphatase 1 PPP1R12A.	Glycine	28-35	Rho guanine nucleotide exchange factor 12	Homo sapiens	150-158
24186203-10	2014	In knockdown experiment, indeed, TAp73 depletion completely abrogates cancer cell proliferation capacity in serine/glycine-deprivation, supporting the role of p73 to help cancer cells under metabolic stress.	Glycine	115-122	tumor protein p73	Homo sapiens	35-38
26717205-3	2016	Results showed that all novel GP(Me)X tripeptides are stable in human plasma (t1/2 &gt; 51 h) and that GP(Me)H - generating stable intramolecular H-bond in a C11-turn by interaction of His imidazole ring and Gly carbonyl group - restored physiological levels of nitric oxide deriving from neuronal NOS (nNOS) activity, thus preventing the inflammatory response by suppression of the NF-kB activity and, consequently, the expression of inflammatory genes such as inducibile NOS (iNOS).	Glycine	208-211	nitric oxide synthase 1	Homo sapiens	289-301
26717205-3	2016	Results showed that all novel GP(Me)X tripeptides are stable in human plasma (t1/2 &gt; 51 h) and that GP(Me)H - generating stable intramolecular H-bond in a C11-turn by interaction of His imidazole ring and Gly carbonyl group - restored physiological levels of nitric oxide deriving from neuronal NOS (nNOS) activity, thus preventing the inflammatory response by suppression of the NF-kB activity and, consequently, the expression of inflammatory genes such as inducibile NOS (iNOS).	Glycine	208-211	nitric oxide synthase 1	Homo sapiens	303-307
31604777-5	2019	SLC6A5 encodes the sodium- and chloride-dependent glycine transporter 2 (GlyT2), which recaptures glycine, a major inhibitory transmitter in the brainstem and spinal cord.	Glycine	50-57	solute carrier family 6 member 5	Homo sapiens	0-6
26432006-5	2016	Two mutant models for IL27 were prepared following the similar protocol by first substituting the tyrosine residues with glycine (MT_G) and then with alanine (MT_A) in the WT protein.	Glycine	121-128	interleukin 27	Homo sapiens	22-26
31604777-5	2019	SLC6A5 encodes the sodium- and chloride-dependent glycine transporter 2 (GlyT2), which recaptures glycine, a major inhibitory transmitter in the brainstem and spinal cord.	Glycine	50-57	solute carrier family 6 member 5	Homo sapiens	73-78
26674175-1	2016	Silk fibroin from the domesticated silkworm Bombyx mori is a naturally occurring biopolymer with charged hydrophilic terminal regions that end-cap a hydrophobic core consisting of repeating sequences of glycine, alanine, and serine residues.	Glycine	203-210	fibroin light chain	Bombyx mori	5-12
31444411-3	2019	Here, we report that the gene encoding glycine decarboxylase (GLDC), which catalyzes the first and rate-limiting step in glycine breakdown with the production of the one-carbon unit 5,10-methylene-tetrahydrofolate, is a direct transcriptional target of MYCN.	Glycine	39-46	glycine decarboxylase	Homo sapiens	62-66
24770882-2	2014	Two additional amino acids: Gly(369) and Gly(370) were observed compared with the reported Nile tilapia transferrin protein sequence.	Glycine	28-31	serotransferrin-like	Oreochromis niloticus	104-115
25178856-4	2014	Inhibition experiments were carried out using Gly-Sar, a typical PepT1 substrate, to confirm the PepT1-mediated transport mechanism of TRH analogs.	Glycine	46-49	thyrotropin releasing hormone	Homo sapiens	135-138
26728993-3	2016	In this study, we found that FXR activation significantly promotes HepG2 cell proliferation accompanied with metabolic switch towards the excessive accumulation of aerobic glycolytic intermediates including lactic acid, pyruvate and the subsequently increased biosynthesis of glycine.	Glycine	276-283	nuclear receptor subfamily 1 group H member 4	Homo sapiens	29-32
31701029-6	2019	Combining KCNQ2- and KCNQ3-specific glycine derivatives synergistically potentiated KCNQ2/3 activation by exploiting heteromeric channel composition.	Glycine	36-43	potassium voltage-gated channel subfamily Q member 3	Homo sapiens	21-26
26381755-7	2016	UBAP2L has an arginine- and glycine-rich motif called the RGG/RG or GAR motif in the N terminus.	Glycine	28-35	ubiquitin associated protein 2 like	Homo sapiens	0-6
25181299-3	2014	The carboxyl termini of mammalian Atg8 homologs are cleaved by Atg4B, a cysteine protease, to expose carboxyl terminal Gly which is essential for this ubiquitylation-like reaction.	Glycine	119-122	autophagy related 4B cysteine peptidase	Homo sapiens	63-68
31611699-5	2019	The slow phosphorylation of Y132, relative to other phosphosites on LAT, is governed by a preceding glycine residue (G131) but can be accelerated by substituting this glycine with aspartate or glutamate.	Glycine	100-107	linker for activation of T cells	Homo sapiens	68-71
25119360-2	2014	The sheath protein Shp-1 stabilizes the structure due to the unique repeat region with Met-Pro-Pro-Gln-Gly sequences.	Glycine	103-106	nuclear receptor subfamily 0 group B member 2	Homo sapiens	19-24
24988361-5	2014	ABPP revealed that the sulfonamide glycine inhibitors have at least three off-targets, including alpha/beta-hydrolase domain 6 (ABHD6).	Glycine	35-42	abhydrolase domain containing 6, acylglycerol lipase	Homo sapiens	97-126
24988361-5	2014	ABPP revealed that the sulfonamide glycine inhibitors have at least three off-targets, including alpha/beta-hydrolase domain 6 (ABHD6).	Glycine	35-42	abhydrolase domain containing 6, acylglycerol lipase	Homo sapiens	128-133
26583619-4	2016	The mother was heterozygous for the HbA2" delta-globin mutation (delta16 (A13) Gly   Arg), thus beta-thalassemia trait was unrecognized due to coinheritance of HbA2".	Glycine	79-82	hemoglobin subunit alpha 2	Homo sapiens	36-40
26160850-0	2015	A Cys-Gly-Cys triad in the dehydrogenase region of Nox2 plays a key role in the interaction with p67phox.	Glycine	6-9	neutrophil cytosolic factor 2	Homo sapiens	97-104
31611699-5	2019	The slow phosphorylation of Y132, relative to other phosphosites on LAT, is governed by a preceding glycine residue (G131) but can be accelerated by substituting this glycine with aspartate or glutamate.	Glycine	167-174	linker for activation of T cells	Homo sapiens	68-71
31652446-6	2019	We found significant associations between glycine and CPS1 (rs1047883) and PC ae C36:0 and CYP4F2 (rs2108622) variants (P<2.05 x 10-7, after the Bonferroni correction for multiple testing).	Glycine	42-49	carbamoyl-phosphate synthase 1	Homo sapiens	54-58
26378241-4	2015	LC3 is a substrate of the cysteine protease ATG4B (Autophagin-1), where cleavage generates a C-terminal glycine required for LC3 conjugation to lipids in autophagosomes.	Glycine	104-111	autophagy related 4B cysteine peptidase	Homo sapiens	44-49
25059720-0	2014	Structural basis for the extended CAP-Gly domains of p150(glued) binding to microtubules and the implication for tubulin dynamics.	Glycine	38-41	chromatin assembly factor 1 subunit A	Homo sapiens	53-57
26378241-4	2015	LC3 is a substrate of the cysteine protease ATG4B (Autophagin-1), where cleavage generates a C-terminal glycine required for LC3 conjugation to lipids in autophagosomes.	Glycine	104-111	autophagy related 4B cysteine peptidase	Homo sapiens	51-63
31621581-2	2019	We recently developed a series of bioactive lipids that inhibit the human glycine transporter GlyT2 (SLC6A5) and provide analgesia in animal models of pain.	Glycine	74-81	solute carrier family 6 member 5	Homo sapiens	94-99
25059720-0	2014	Structural basis for the extended CAP-Gly domains of p150(glued) binding to microtubules and the implication for tubulin dynamics.	Glycine	38-41	chromatin assembly factor 1 subunit A	Homo sapiens	58-63
25059720-3	2014	p150(glued) contains an N-terminal microtubule-binding cytoskeleton-associated protein glycine-rich (CAP-Gly) domain that accelerates tubulin polymerization.	Glycine	87-94	chromatin assembly factor 1 subunit A	Homo sapiens	0-4
25059720-3	2014	p150(glued) contains an N-terminal microtubule-binding cytoskeleton-associated protein glycine-rich (CAP-Gly) domain that accelerates tubulin polymerization.	Glycine	87-94	chromatin assembly factor 1 subunit A	Homo sapiens	5-10
25059720-3	2014	p150(glued) contains an N-terminal microtubule-binding cytoskeleton-associated protein glycine-rich (CAP-Gly) domain that accelerates tubulin polymerization.	Glycine	105-108	chromatin assembly factor 1 subunit A	Homo sapiens	0-4
25059720-3	2014	p150(glued) contains an N-terminal microtubule-binding cytoskeleton-associated protein glycine-rich (CAP-Gly) domain that accelerates tubulin polymerization.	Glycine	105-108	chromatin assembly factor 1 subunit A	Homo sapiens	5-10
25059720-6	2014	Cryo-EM 3D reconstructions of p150(glued)-CAP-Gly complexed with microtubules revealed the recognition of the microtubule surface, including tubulin C-terminal tails by CAP-Gly.	Glycine	46-49	chromatin assembly factor 1 subunit A	Homo sapiens	30-34
25059720-6	2014	Cryo-EM 3D reconstructions of p150(glued)-CAP-Gly complexed with microtubules revealed the recognition of the microtubule surface, including tubulin C-terminal tails by CAP-Gly.	Glycine	46-49	chromatin assembly factor 1 subunit A	Homo sapiens	35-40
25059720-6	2014	Cryo-EM 3D reconstructions of p150(glued)-CAP-Gly complexed with microtubules revealed the recognition of the microtubule surface, including tubulin C-terminal tails by CAP-Gly.	Glycine	173-176	chromatin assembly factor 1 subunit A	Homo sapiens	30-34
25059720-6	2014	Cryo-EM 3D reconstructions of p150(glued)-CAP-Gly complexed with microtubules revealed the recognition of the microtubule surface, including tubulin C-terminal tails by CAP-Gly.	Glycine	173-176	chromatin assembly factor 1 subunit A	Homo sapiens	35-40
25059720-9	2014	This shielding effect of CAP-Gly and its basic extensions may provide a molecular basis of the roles of p150(glued) in microtubule dynamics.	Glycine	29-32	chromatin assembly factor 1 subunit A	Homo sapiens	104-108
25059720-9	2014	This shielding effect of CAP-Gly and its basic extensions may provide a molecular basis of the roles of p150(glued) in microtubule dynamics.	Glycine	29-32	chromatin assembly factor 1 subunit A	Homo sapiens	109-114
24962068-4	2014	N-arachidonyl-glycine (NAGly) is an endogenous lipid that inhibits glycine transport by GlyT2 and also shows potential as an analgesic, which may be further exploited in drug development.	Glycine	14-21	solute carrier family 6 member 5	Homo sapiens	88-93
24978476-8	2014	When ERRgamma-Asn346 was replaced by the corresponding Gly and Tyr in ERRalpha and ERRbeta, respectively, the binding affinity of BPA and even 4-hydroxytamxifen (4-OHT) is much reduced.	Glycine	55-58	estrogen related receptor gamma	Homo sapiens	5-13
24952539-5	2014	The main characteristics of core ionization induced fragmentation of glycine were found to be the rupture of the C-Calpha bond and the presence of the CNH(2)(+) fragment.	Glycine	69-76	fibrillin 2	Homo sapiens	113-121
24459296-4	2014	We now demonstrate the existence of a new post-translational modification of HTT: the addition of the 14 carbon fatty acid myristate to a glycine residue exposed on a caspase-3-cleaved fragment (post-translational myristoylation) and that myristoylation of this fragment is altered in a physiologically relevant model of mutant HTT.	Glycine	138-145	huntingtin	Homo sapiens	77-80
24459296-4	2014	We now demonstrate the existence of a new post-translational modification of HTT: the addition of the 14 carbon fatty acid myristate to a glycine residue exposed on a caspase-3-cleaved fragment (post-translational myristoylation) and that myristoylation of this fragment is altered in a physiologically relevant model of mutant HTT.	Glycine	138-145	huntingtin	Homo sapiens	328-331
24650999-11	2014	RESULTS: Based on high performance gel permeation chromatography (HPGPC), Fourier transform infrared (FT-IR) and nuclear magnetic resonance (NMR) analyses, the isolated protein (PEP) had a molecular weight of 63 kDa, a secondary (alpha-helical) structure and was mainly composed of arginine, serine and glycine.	Glycine	303-310	prolyl endopeptidase	Homo sapiens	178-181
24652275-5	2014	It leads to the leach-proof binding of the capture Ab, which means that the developed SPR IA is highly cost-effective, as the Ab-bound SPR chip could be reused for many repeated HFA IAs after regeneration with 10 mM glycine-HCl, pH 2.0.	Glycine	216-227	small proline rich protein 1A	Homo sapiens	86-92
24627494-3	2014	We explored the hypothesis that a conserved His-rich cluster (His-Gly-His-His) in the linker region connecting its two catalytic domains senses pH and affects PAM trafficking by mutating these His residues to Ala (Ala-Gly-Ala-Ala; H3A).	Glycine	66-69	peptidylglycine alpha-amidating monooxygenase	Mus musculus	159-162
24726729-1	2014	Cellular nucleic acid binding protein (CNBP) contains seven zinc finger (ZF) repeats and an arginine and glycine (RG) rich sequence between the first and the second ZF.	Glycine	105-112	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	0-37
24726729-1	2014	Cellular nucleic acid binding protein (CNBP) contains seven zinc finger (ZF) repeats and an arginine and glycine (RG) rich sequence between the first and the second ZF.	Glycine	105-112	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	39-43
24390667-7	2014	In conclusion, the most abundantly expressed serine/glycine metabolism-related protein in basal-like TNBC tissues was tumoral PHGDH, and expression levels of stromal SHMT1 and tumoral PHGDH were inversely correlated with clinical prognostic factors.	Glycine	52-59	phosphoglycerate dehydrogenase	Homo sapiens	126-131
24390667-7	2014	In conclusion, the most abundantly expressed serine/glycine metabolism-related protein in basal-like TNBC tissues was tumoral PHGDH, and expression levels of stromal SHMT1 and tumoral PHGDH were inversely correlated with clinical prognostic factors.	Glycine	52-59	phosphoglycerate dehydrogenase	Homo sapiens	184-189
24747353-4	2014	Myosin IB is a monomeric, non-filamentous myosin with a globular head that binds to F-actin and has motor activity, and a non-helical tail comprising a basic region, a glycine-proline-glutamine-rich region and an SH3-domain.	Glycine	168-175	myosin IB	Homo sapiens	0-9
24747353-10	2014	We conclude that myosin IB contributes to anchoring actin waves to the plasma membranes by binding of the basic-hydrophobic site to acidic phospholipids in the plasma membrane and binding of the Gly-Pro-Gln region to F-actin in the wave.	Glycine	195-198	myosin IB	Homo sapiens	17-26
24520911-0	2014	Mutations to a glycine loop in the catalytic site of human Lon changes its protease, peptidase and ATPase activities.	Glycine	15-22	dynein axonemal heavy chain 8	Homo sapiens	99-105
25016858-8	2014	CONCLUSION: Gly may mediate HHPV via activating ERK1/2 signal transduction pathway.	Glycine	12-15	mitogen activated protein kinase 3	Rattus norvegicus	48-54
24498414-6	2014	ERGIC-53 has a shallower sugar-binding pocket than VIP36 because of the single amino acid substitution, Asp-to-Gly.	Glycine	111-114	lectin, mannose binding 1	Homo sapiens	0-8
24466094-4	2014	CYB5D2 binds to type b heme, however, only the substitution of glycine (G) at D86 (D86G) within its cytochrome b5 heme-binding (cyt-b5) domain abolished its heme-binding ability.	Glycine	63-70	cytochrome b5 domain containing 2	Homo sapiens	0-6
25030758-3	2014	One of these genes is called interferon stimulated gene 15 (ISG15), which encodes a ubiquitin homolog with a C-terminal Gly that becomes covalently attached to Lys residues on targeted proteins through an ATP-dependent multi-step enzymatic reaction called ISGylation.	Glycine	120-123	ISG15 ubiquitin like modifier	Homo sapiens	29-58
25030758-3	2014	One of these genes is called interferon stimulated gene 15 (ISG15), which encodes a ubiquitin homolog with a C-terminal Gly that becomes covalently attached to Lys residues on targeted proteins through an ATP-dependent multi-step enzymatic reaction called ISGylation.	Glycine	120-123	ISG15 ubiquitin like modifier	Homo sapiens	60-65
24931196-5	2014	Constitutively active mutants (CAMs) of AT1 receptor have been engineered using molecular modeling and site-directed mutagenesis approaches among which substitution of Asn(111) in the transmembrane helix III with glycine or serine results in the highest basal activity of the receptor.	Glycine	213-220	angiotensin II receptor type 1	Homo sapiens	40-43
25036958-5	2014	Additionally, point mutagenesis analysis showed that the substitution of Asp by Gly within the Pro-Val-Asp-Leu-Thr (PVDLT) motif of gKLF3 significantly reduced the ability of gKLF3 to regulate the promoter activities of FABP4, FASN, LPL, C/EBPalpha, and PPARgamma.	Glycine	80-83	fatty acid binding protein 4	Gallus gallus	220-225
25036958-5	2014	Additionally, point mutagenesis analysis showed that the substitution of Asp by Gly within the Pro-Val-Asp-Leu-Thr (PVDLT) motif of gKLF3 significantly reduced the ability of gKLF3 to regulate the promoter activities of FABP4, FASN, LPL, C/EBPalpha, and PPARgamma.	Glycine	80-83	lipoprotein lipase	Gallus gallus	233-236
25036958-5	2014	Additionally, point mutagenesis analysis showed that the substitution of Asp by Gly within the Pro-Val-Asp-Leu-Thr (PVDLT) motif of gKLF3 significantly reduced the ability of gKLF3 to regulate the promoter activities of FABP4, FASN, LPL, C/EBPalpha, and PPARgamma.	Glycine	80-83	CCAAT/enhancer binding protein alpha	Gallus gallus	238-248
25036958-5	2014	Additionally, point mutagenesis analysis showed that the substitution of Asp by Gly within the Pro-Val-Asp-Leu-Thr (PVDLT) motif of gKLF3 significantly reduced the ability of gKLF3 to regulate the promoter activities of FABP4, FASN, LPL, C/EBPalpha, and PPARgamma.	Glycine	80-83	peroxisome proliferator-activated receptor gamma	Gallus gallus	254-263
23994185-4	2013	The glycine transporter 2 (GlyT2) regulates the uptake of glycine into presynaptic boutons.	Glycine	4-11	solute carrier family 6 member 5	Homo sapiens	27-32
24259588-9	2013	Using the glycine-induced, NMDA-dependent form of chemical long-term potentiation (LTP) in cultured cortical neurons, we showed that CD3zeta was required for activity-dependent CaMKII autophosphorylation and for the synaptic recruitment of the AMPAR subunit GluA1.	Glycine	10-17	glutamate receptor, ionotropic, AMPA1 (alpha 1)	Mus musculus	244-249
24259588-9	2013	Using the glycine-induced, NMDA-dependent form of chemical long-term potentiation (LTP) in cultured cortical neurons, we showed that CD3zeta was required for activity-dependent CaMKII autophosphorylation and for the synaptic recruitment of the AMPAR subunit GluA1.	Glycine	10-17	glutamate receptor, ionotropic, AMPA1 (alpha 1)	Mus musculus	258-263
23640702-3	2013	Our results show that GLY reduced CO2 production using glucose as substrate and inhibited the activities of citrate synthase and isocitrate dehydrogenase in striatum, whereas no alterations of these parameters were verified in cerebral cortex 30 min after GLY injection.	Glycine	22-25	citrate synthase	Rattus norvegicus	108-124
24349641-0	2013	Effects of the Arg-Pro and Gly-Gly-Nle Moieties on Melanocortin-1 Receptor Binding Affinities of alpha-MSH Peptides.	Glycine	27-30	pro-opiomelanocortin-alpha	Mus musculus	97-106
24349641-0	2013	Effects of the Arg-Pro and Gly-Gly-Nle Moieties on Melanocortin-1 Receptor Binding Affinities of alpha-MSH Peptides.	Glycine	31-34	pro-opiomelanocortin-alpha	Mus musculus	97-106
23553550-11	2013	When NHE1 and AE2 activities were maintained in GV oocytes by exogenous expression, glycine accumulation was inhibited.	Glycine	84-91	solute carrier family 4 (anion exchanger), member 2	Mus musculus	14-17
23952283-5	2013	We further demonstrate the use of the metamaterials for fingerprinting and detection of the arginine-glycine-glycine domain of nucleolin, a cancer biomarker that specifically binds to a G-quadruplex, with the picomolar sensitivity.	Glycine	101-108	nucleolin	Homo sapiens	127-136
23952283-5	2013	We further demonstrate the use of the metamaterials for fingerprinting and detection of the arginine-glycine-glycine domain of nucleolin, a cancer biomarker that specifically binds to a G-quadruplex, with the picomolar sensitivity.	Glycine	109-116	nucleolin	Homo sapiens	127-136
23912193-3	2013	An active mature CLV3 is a tridecapeptide linked to beta-L-Araf-(1 2)-beta-L-Araf-(1 2)-beta-L-Araf at a Hyp residue in the center of the peptide sequence such as Arg-Thr-Val-Hyp-Ser-Gly-Hyp(L-Arafn)-Asp-Pro-Leu-His-His-His (n = 3).	Glycine	183-186	CLAVATA3	Arabidopsis thaliana	17-21
23912193-3	2013	An active mature CLV3 is a tridecapeptide linked to beta-L-Araf-(1 2)-beta-L-Araf-(1 2)-beta-L-Araf at a Hyp residue in the center of the peptide sequence such as Arg-Thr-Val-Hyp-Ser-Gly-Hyp(L-Arafn)-Asp-Pro-Leu-His-His-His (n = 3).	Glycine	183-186	alpha-L-arabinofuranosidase 1	Arabidopsis thaliana	59-63
23912193-3	2013	An active mature CLV3 is a tridecapeptide linked to beta-L-Araf-(1 2)-beta-L-Araf-(1 2)-beta-L-Araf at a Hyp residue in the center of the peptide sequence such as Arg-Thr-Val-Hyp-Ser-Gly-Hyp(L-Arafn)-Asp-Pro-Leu-His-His-His (n = 3).	Glycine	183-186	alpha-L-arabinofuranosidase 1	Arabidopsis thaliana	77-81
23912193-3	2013	An active mature CLV3 is a tridecapeptide linked to beta-L-Araf-(1 2)-beta-L-Araf-(1 2)-beta-L-Araf at a Hyp residue in the center of the peptide sequence such as Arg-Thr-Val-Hyp-Ser-Gly-Hyp(L-Arafn)-Asp-Pro-Leu-His-His-His (n = 3).	Glycine	183-186	alpha-L-arabinofuranosidase 1	Arabidopsis thaliana	77-81
23804454-7	2013	Experiments with recombinant occludin demonstrated that meprin A cleaves the protein between Gly(100) and Ser(101) on the first extracellular loop.	Glycine	93-96	occludin	Canis lupus familiaris	29-37
23962100-13	2013	The NMDA subunits NR2b and NR2a, in addition to the N-terminal region of the glycine binding NR1 subunit, have been implicated.	Glycine	77-84	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	18-22
26092730-10	2015	Thus, SMN tetramers do not form symmetric helical bundles such as those found in glycine zipper transmembrane oligomers.	Glycine	81-88	survival of motor neuron 1, telomeric	Homo sapiens	6-9
26244639-9	2015	Adducts derive from two arginine residues, Arg22 and Arg23 near the C-terminus, and the N-terminal glycine (Gly1).	Glycine	99-106	threonine aldolase 1, pseudogene	Homo sapiens	108-112
25988540-10	2015	Glycine increased the mRNA expression of eNOS and decreased the expression of COX-2 and TNF-alpha.	Glycine	0-7	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	78-83
26047115-2	2015	Carboxylesterases underwent two divergent evolutionary events: (1) quantitative mechanism characterized by the overproduction of carboxylesterase protein; and (2) qualitative mechanism caused by changes in enzymatic properties because of mutation from glycine/alanine to aspartate at the 151 site (G/A151D) or from tryptophan to leucine at the 271 site (W271L), following the numbering of Drosophila melanogaster AChE.	Glycine	252-259	Acetylcholine esterase	Drosophila melanogaster	413-417
25858298-3	2015	HbA2" [delta16 (A13) Gly Arg (GGC CGC)] is a delta-chain variant that has been identified in several populations of African origin.	Glycine	21-24	hemoglobin subunit alpha 2	Homo sapiens	0-4
25710242-3	2015	RECENT FINDINGS: Strategies focused on enhancing activity of the N-methyl D-aspartate (NMDA) receptor via direct agonists at the glycine site or by inhibition of glycine reuptake have produced modest and often inconsistent evidence of efficacy, as have approaches to reduce excessive glutamate release by lamotrigine or by mGluR2/3 agonists.	Glycine	162-169	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	323-329
25808954-3	2015	While otherwise dissimilar in primary sequence, these Prp43-binding proteins each contain a short glycine-rich G-patch motif required for function and thought to act in protein or nucleic acid recognition.	Glycine	98-105	DEAH-box ATP-dependent RNA helicase PRP43	Saccharomyces cerevisiae S288C	54-59
25568307-14	2015	In addition, the GSK3A isoform, with its highly conserved glycine-rich N terminus in mammals, may have an isoform-specific role in its requirement for normal sperm motility and fertility.	Glycine	58-65	glycogen synthase kinase 3 alpha	Mus musculus	17-22
25134804-6	2015	We found an association between the hMSH2 Asp/Asp and Gly/Asp genotypes and TNBC occurence.	Glycine	54-57	mutS homolog 2	Homo sapiens	36-41
25317566-4	2015	Structural analysis reveals that the covalent bond between FIIN-2 and a cysteine, uniquely present in the glycine-rich loop of FGFR kinases, facilitates the DFG-out conformation, which together with the internal flexibility of FIIN-2 enables FIIN-2 to avoid the steric clash with the gate-keeper mutation that causes the ponatinib resistance.	Glycine	106-113	fibroblast growth factor receptor 4	Homo sapiens	127-131
25451930-4	2015	Despite its hyperfunctionality, we found the Arg-389 variant of ADRB1 to be hyperphosphorylated upon continuous stimulation with norepinephrine compared with the Gly-389 variant.	Glycine	162-165	adrenoceptor beta 1	Homo sapiens	64-69
25451930-5	2015	Using ADRB1 sensors to monitor activation kinetics by fluorescence resonance energy transfer, Arg-389-ADRB1 exerted faster activation speed and arrestin recruitment than the Gly-389 variant.	Glycine	174-177	adrenoceptor beta 1	Homo sapiens	102-107
25452809-4	2015	PAR-2 mRNA was significantly upregulated in the cells treated with trypsin or the PAR-2 activating peptide Ser-Leu-Ile-Gly-Lys-Val (SLIGKV) (P&lt;0.01), but not in the Val-Lys-Gly-Ile-Leu-Ser group (P&gt;0.05).	Glycine	119-122	F2R like trypsin receptor 1	Homo sapiens	0-5
25452809-4	2015	PAR-2 mRNA was significantly upregulated in the cells treated with trypsin or the PAR-2 activating peptide Ser-Leu-Ile-Gly-Lys-Val (SLIGKV) (P&lt;0.01), but not in the Val-Lys-Gly-Ile-Leu-Ser group (P&gt;0.05).	Glycine	119-122	F2R like trypsin receptor 1	Homo sapiens	82-87
25452809-4	2015	PAR-2 mRNA was significantly upregulated in the cells treated with trypsin or the PAR-2 activating peptide Ser-Leu-Ile-Gly-Lys-Val (SLIGKV) (P&lt;0.01), but not in the Val-Lys-Gly-Ile-Leu-Ser group (P&gt;0.05).	Glycine	176-179	F2R like trypsin receptor 1	Homo sapiens	0-5
25452809-4	2015	PAR-2 mRNA was significantly upregulated in the cells treated with trypsin or the PAR-2 activating peptide Ser-Leu-Ile-Gly-Lys-Val (SLIGKV) (P&lt;0.01), but not in the Val-Lys-Gly-Ile-Leu-Ser group (P&gt;0.05).	Glycine	176-179	F2R like trypsin receptor 1	Homo sapiens	82-87
25399235-0	2014	Low energy conformations for gonadotropin-releasing hormone with D- and L-amino acid substitutions for Gly 6: possible receptor-bound conformations.	Glycine	103-106	gonadotropin releasing hormone 1	Homo sapiens	29-59
25404067-1	2014	Using the chain-build-up method based on Empirical Conformational Energies of Peptides Program including solvation, we have computed, the low energy conformations of gonadotrpin-releasing hormone, GnRH, whose sequence is Pyro-Glu(PG)-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2.	Glycine	250-253	gonadotropin releasing hormone 1	Homo sapiens	197-201
25404067-8	2014	This can explain why substitutions of L-amino acids for Gly 6 are known to inactivate GnRH while D-amino acid substitutions enhance its activity.	Glycine	56-59	gonadotropin releasing hormone 1	Homo sapiens	86-90
25377064-1	2014	A previous study documented a glycine to glutamic acid mutation (G4946E) in ryanodine receptor (RyR) was highly correlated to diamide insecticide resistance in field populations of Plutella xylostella (Lepidoptera: Plutellidae).	Glycine	30-37	ryanodine receptor	Plutella xylostella	76-94
25377064-1	2014	A previous study documented a glycine to glutamic acid mutation (G4946E) in ryanodine receptor (RyR) was highly correlated to diamide insecticide resistance in field populations of Plutella xylostella (Lepidoptera: Plutellidae).	Glycine	30-37	ryanodine receptor	Plutella xylostella	96-99
25058638-5	2014	Notably, multiple strong [PSI+] variants can be maintained by a minimal construct of Sis1 consisting of only the J-domain and glycine/phenylalanine-rich (G/F) region that was previously shown to be sufficient for cell viability and [RNQ+] prion propagation.	Glycine	126-133	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	85-89
25058638-8	2014	These observations necessitate that Sis1 must have at least two distinct functional roles that individual prions differentially require for propagation and which are localized to the glycine-rich domains of the Sis1.	Glycine	183-190	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	36-40
25058638-8	2014	These observations necessitate that Sis1 must have at least two distinct functional roles that individual prions differentially require for propagation and which are localized to the glycine-rich domains of the Sis1.	Glycine	183-190	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	211-215
24933025-10	2014	The glutamine-to-glutamic acid ratio and glycine were inversely correlated (i.e., LH &gt; MHO &gt; MUO) with HbA1c values.	Glycine	41-48	hemoglobin subunit alpha 1	Homo sapiens	109-113
24681163-9	2014	Additional substitution of the 11th Gly with Asp was found by comparison with human sEH which has phosphatase activity, but the Xenopus sEH mutant G11D prepared as mutant 2 did not have phosphatase activity.	Glycine	36-39	epoxide hydrolase 2	Homo sapiens	84-87
24979213-5	2014	GLDC, associated with glycine metabolism, was highly expressed in HER-2-positive MDA-MB-453 and TNBC-related MDA-MB-435S.	Glycine	22-29	glycine decarboxylase	Homo sapiens	0-4
24850085-12	2014	The active peptide sequence alignments suggest that the syndecan-binding peptides contain a "basic amino acid (BAA)-Gly-BAA" motif in the middle of the molecule and that the integrin-binding peptides contain an "acidic amino acid (AAA)"-Gly-BAA motif.	Glycine	116-119	syndecan 1	Homo sapiens	56-64
24850085-12	2014	The active peptide sequence alignments suggest that the syndecan-binding peptides contain a "basic amino acid (BAA)-Gly-BAA" motif in the middle of the molecule and that the integrin-binding peptides contain an "acidic amino acid (AAA)"-Gly-BAA motif.	Glycine	237-240	syndecan 1	Homo sapiens	56-64
24614658-6	2014	In contrast to native Crp-4, the (I23/F25/L26/G)-Crp-4 variant lacked bactericidal activity against Salmonella enterica serovar Typhimurium and did not permeabilize Escherichia coli ML35 cells as a result of removing aliphatic side chains by Gly substitutions.	Glycine	242-245	defensin, alpha, 4	Mus musculus	49-54
25121058-4	2014	Salivary Beta Glucuronidase activity was measured using spectrophotometer with reagents like phenolphthalein glucuronic acid, phosphate and glycine buffer.	Glycine	140-147	glucuronidase beta	Homo sapiens	9-27
24648513-0	2014	Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).	Glycine	50-57	Ras homolog, mTORC1 binding	Homo sapiens	61-65
24440425-5	2014	The sequence containing residues L962 to Y976 of the TMD of the IR in micelles adopts a well-defined helical structure with a kink formed by glycine and proline residues present at its N-terminus, which might be important for its function.	Glycine	141-148	insulin receptor	Homo sapiens	64-66
24792626-8	2014	The c.694A&gt;C substitution in FOXP3 results in a cysteine-to-glycine change at the protein position 232 that is completely conserved among all vertebrates.	Glycine	63-70	forkhead box P3	Homo sapiens	32-37
24266811-4	2014	Synaptic concentrations of D-serine and glycine are regulated by the amino acid transporter alanine serine cysteine transporter-1 (asc-1).	Glycine	40-47	solute carrier family 7 member 10	Homo sapiens	100-136
24266811-5	2014	Inhibition of asc-1 would increase synaptic D-serine and possibly glycine, eliminating the need for high-dose systemic D-serine or glycine treatment.	Glycine	66-73	solute carrier family 7 member 10	Homo sapiens	14-19
24266811-5	2014	Inhibition of asc-1 would increase synaptic D-serine and possibly glycine, eliminating the need for high-dose systemic D-serine or glycine treatment.	Glycine	131-138	solute carrier family 7 member 10	Homo sapiens	14-19
24407464-0	2014	Diagnosis of glycine encephalopathy in a pediatric patient by detection of a GLDC mutation during initial next generation DNA sequencing.	Glycine	13-20	glycine decarboxylase	Homo sapiens	77-81
24407464-4	2014	The patient was found to have glycine encephalopathy resulting from a previously defined mutation in the GLDC gene.	Glycine	30-37	glycine decarboxylase	Homo sapiens	105-109
23997037-11	2014	Sequencing analysis of the three exons of the TTF1 revealed a heterozygous mutation c.334G &gt; T that results in the replacement of glycine in position 112 with a stop codon, generating a nonsense protein that lacks the correct transactivation domain in the C-terminal region.	Glycine	133-140	transcription termination factor 1	Homo sapiens	46-50
24467211-1	2014	Glycine decarboxylase (GLDC) is a metabolic oncogene that links glycine metabolism with tumorigenesis.	Glycine	64-71	glycine decarboxylase	Homo sapiens	0-21
24467211-1	2014	Glycine decarboxylase (GLDC) is a metabolic oncogene that links glycine metabolism with tumorigenesis.	Glycine	64-71	glycine decarboxylase	Homo sapiens	23-27
24467211-2	2014	In humans, GLDC is part of a multienzyme complex (which includes the lipoyl-containing H-protein) that couples the decarboxylation of glycine to the biosynthesis of serine.	Glycine	134-141	glycine decarboxylase	Homo sapiens	11-15
24467211-3	2014	Details of the GLDC-catalyzed glycine decarboxylation reaction are critical to drug development but remain elusive.	Glycine	30-37	glycine decarboxylase	Homo sapiens	15-19
24467211-4	2014	This is the first report on the mechanism of the GLDC-catalyzed reaction and shows that GLDC is an unusual PLP-containing alpha-amino acid decarboxylase that removes carbon dioxide from the glycine substrate without releasing the expected amine (methylamine, a metabolic precursor of toxic formaldehyde) as a product.	Glycine	190-197	glycine decarboxylase	Homo sapiens	49-53
24467211-4	2014	This is the first report on the mechanism of the GLDC-catalyzed reaction and shows that GLDC is an unusual PLP-containing alpha-amino acid decarboxylase that removes carbon dioxide from the glycine substrate without releasing the expected amine (methylamine, a metabolic precursor of toxic formaldehyde) as a product.	Glycine	190-197	glycine decarboxylase	Homo sapiens	88-92
24382305-11	2014	A structure of a G86D-DNA complex reveals a rearrangement in the beta4/5 loop comprising Leu84, the highly-conserved void-filling residue, thereby providing a structural rationale for the decreased glycosylase activity of the glycine to aspartate variant.	Glycine	226-233	tubulin beta 3 class III	Homo sapiens	65-72
24284322-3	2014	Here we show that the EBNA1-nucleophosmin interaction is direct and requires the Gly-Arg-rich sequences that contribute to transactivation.	Glycine	81-84	nucleophosmin 1	Homo sapiens	28-41
24297171-9	2014	Of the MMPs tested, MMP-2 and MMP-9 most greatly favored the presence of charged residues with preference for the Gly-Asp-Lys series.	Glycine	114-117	matrix metallopeptidase 2	Homo sapiens	7-11
24297171-9	2014	Of the MMPs tested, MMP-2 and MMP-9 most greatly favored the presence of charged residues with preference for the Gly-Asp-Lys series.	Glycine	114-117	matrix metallopeptidase 2	Homo sapiens	20-25
24297171-12	2014	More specifically, the lack of Gly-Asp-Lys clusters may diminish potential MMP-2 and MMP-9 collagenolytic activity.	Glycine	31-34	matrix metallopeptidase 2	Homo sapiens	75-80
24378034-3	2014	We report herein a novel set of SrtA substrates (LPETGG-isoacyl-Ser and LPETGG-isoacyl-Hse) that can be irreversibly ligated to N-terminal Gly-containing moieties via the deactivation of the SrtA-excised peptide fragment through diketopiperazine (DKP) formation.	Glycine	139-142	hydroxysteroid 17-beta dehydrogenase 6	Homo sapiens	87-90
23742196-4	2014	This effect of glycine could be because of the increased amount of glutathione synthetase, which may be responsible for increased glutathione (GSH) content in vascular tissue from SF rats.	Glycine	15-22	glutathione synthetase	Rattus norvegicus	67-89
25531100-7	2014	Coexpression of OSR1 significantly decreased Igly-gly in both PEPT1 and PEPT2 expressing oocytes.	Glycine	46-49	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	62-67
25531100-8	2014	The effect of OSR1 coexpression on Igly-gly in PEPT1 expressing oocytes was mimicked by coexpression of (T185E)OSR1, but not of (D164A)OSR1 or (T185A)OSR1.	Glycine	36-39	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	47-52
24264576-3	2014	The zinc metalloendopeptidase, EC 3.4.24.15 (EP24.15), can cleave GnRH at the Tyr(5)-Gly(6) bond to form the pentapeptide, GnRH-(1-5).	Glycine	85-88	gonadotropin releasing hormone 1	Homo sapiens	66-70
24264576-3	2014	The zinc metalloendopeptidase, EC 3.4.24.15 (EP24.15), can cleave GnRH at the Tyr(5)-Gly(6) bond to form the pentapeptide, GnRH-(1-5).	Glycine	85-88	gonadotropin releasing hormone 1	Homo sapiens	123-132
24121506-5	2013	Within L1C domains, five amino acid residues (Leu-135, Gly-188, Arg-244, and vicinal His-318 and Lys-319) were identified as IRR-specific by species conservation analysis of the IR family.	Glycine	55-58	insulin receptor	Homo sapiens	125-127
24038877-0	2013	Position of glycine substitutions in the triple helix of COL6A1, COL6A2, and COL6A3 is correlated with severity and mode of inheritance in collagen VI myopathies.	Glycine	12-19	collagen type VI alpha 2 chain	Homo sapiens	65-71
24038877-2	2013	We describe clinical and genetic characteristics of 97 individuals with glycine substitutions in the TH domain of COL6A1, COL6A2, or COL6A3 and add a review of 97 published cases, for a total of 194 cases.	Glycine	72-79	collagen type VI alpha 2 chain	Homo sapiens	122-128
24082117-6	2013	Nucleolin, a protein with histone chaperone activity, interacts with RAD50 via its arginine-glycine rich domain and is recruited to DSBs rapidly in an MRE11-NBS1-RAD50 complex-dependent manner.	Glycine	92-99	nucleolin	Homo sapiens	0-9
24082117-6	2013	Nucleolin, a protein with histone chaperone activity, interacts with RAD50 via its arginine-glycine rich domain and is recruited to DSBs rapidly in an MRE11-NBS1-RAD50 complex-dependent manner.	Glycine	92-99	RAD50 double strand break repair protein	Homo sapiens	69-74
23913323-7	2013	A change of the conserved glutamate residue in the putative catalytic center of the SLT domain (E87) to glycine resulted in almost complete inactivity, which is consistent with this part of TraG being a predicted lytic transglycosylase.	Glycine	104-111	transfer related gene	Enterococcus faecalis	190-194
26344341-7	2013	Humoral immune responses elicited by heterologus prime-boost immunization with a plasmid encoding HIV-1 from gp160 followed by protein boosting could be enhanced by use of pFliC(-gly).	Glycine	179-182	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	109-114
23690564-1	2013	Fast inhibitory neurotransmission in the central nervous system is mediated by gamma-aminobutyric acid (GABA) and glycine, which are accumulated into synaptic vesicles by a common vesicular inhibitory amino acid transporter (VIAAT) and are then co-released.	Glycine	114-121	solute carrier family 32 member 1	Rattus norvegicus	180-223
23690564-1	2013	Fast inhibitory neurotransmission in the central nervous system is mediated by gamma-aminobutyric acid (GABA) and glycine, which are accumulated into synaptic vesicles by a common vesicular inhibitory amino acid transporter (VIAAT) and are then co-released.	Glycine	114-121	solute carrier family 32 member 1	Rattus norvegicus	225-230
23690564-3	2013	In this study, we demonstrate the dynamic control of the GABA-glycine co-transmission by the neuronal glutamate transporter, using paired whole-cell patch recording from monosynaptically coupled cultured spinal cord neurons derived from VIAAT-Venus transgenic rats.	Glycine	62-69	solute carrier family 32 member 1	Rattus norvegicus	237-242
23883194-2	2013	Liquid chromatography experiments demonstrated that in the presence of excess Q7, APN quantitatively converts the pentapeptides Thr-Gly-Ala-X-Met into the dipeptides X-Met (X = Phe, AMPhe).	Glycine	132-135	alanyl aminopeptidase, membrane	Homo sapiens	82-85
23696644-7	2013	We also demonstrate, using solution biochemistry methods and EM, the rescue of filament formation by drebrin in different cases of longitudinal interprotomer contact perturbation: the T203C/C374S yeast actin mutant and grimelysin-cleaved skeletal actin (between Gly-42 and Val-43).	Glycine	262-265	drebrin 1	Homo sapiens	101-108
23599269-5	2013	RNA-binding domain 4 and the glycine/arginine-rich domain of nucleolin were essential for its association with Fas.	Glycine	29-36	nucleolin	Homo sapiens	61-70
23466492-3	2013	In this study, we report that alpha-actinin-4 is initially cleaved by m-calpain between tyrosine 13 and glycine.	Glycine	104-111	actinin alpha 4	Homo sapiens	30-45
23642268-7	2013	Three identified proteins: splicing factor, proline- and glutamine-rich (SFPQ), heterogeneous nuclear ribonucleoprotein D-like (hnRNP DL) and cellular nucleic acid binding protein (CNBP) are known to contain methylarginines in their glycine and arginine rich (GAR) sequences.	Glycine	233-240	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	142-179
23642268-7	2013	Three identified proteins: splicing factor, proline- and glutamine-rich (SFPQ), heterogeneous nuclear ribonucleoprotein D-like (hnRNP DL) and cellular nucleic acid binding protein (CNBP) are known to contain methylarginines in their glycine and arginine rich (GAR) sequences.	Glycine	233-240	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	181-185
23888783-6	2013	The comparison of the occurrence of 20 amino acids for syndecan-1 from 32 animal organisms and 17 animal proteomes demonstrated that for the first such amino acids as glycine, treonine, glutamine, glutamic acid, and proline predominate on amount in the content of the former that results to the appearance of disordered regions in the proteins.	Glycine	167-174	syndecan 1	Homo sapiens	55-65
23650557-1	2013	The neuronal transporter GlyT2 is a polytopic, 12-transmembrane domain, plasma membrane glycoprotein involved in the removal and recycling of synaptic glycine from inhibitory synapses.	Glycine	151-158	solute carrier family 6 member 5	Homo sapiens	25-30
23423655-4	2013	Recently, we proposed that this transformation, an N-S acyl shift, is accelerated by a localized conformational strain, between the intein"s catalytic cysteine (Cys1) and the neighboring glycine (Gly-1) in the N-extein.	Glycine	187-194	threonine aldolase 1, pseudogene	Homo sapiens	196-201
23550886-0	2013	Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A.	Glycine	64-71	outer membrane porin F	Escherichia coli str. K-12 substr. MG1655	85-95
31621581-2	2019	We recently developed a series of bioactive lipids that inhibit the human glycine transporter GlyT2 (SLC6A5) and provide analgesia in animal models of pain.	Glycine	74-81	solute carrier family 6 member 5	Homo sapiens	101-107
23386608-4	2013	A glycine zipper motif present in one of the transmembrane domains of RHBDD2 is important for its packing into the Golgi membranes.	Glycine	2-9	rhomboid domain containing 2	Homo sapiens	70-76
31548413-6	2019	We also found that the synaptic NMDAR activation in adult SR-knockout (KO) mice requires Phgdh-derived glycine, despite the sharp decline in the postnatal glycine levels as a result of the emergence of the glycine cleavage system.	Glycine	103-110	3-phosphoglycerate dehydrogenase	Mus musculus	89-94
23509275-5	2013	In-frame TGA (opal) codons are found in most genes (85%), often at loci normally encoding conserved glycine residues.	Glycine	100-107	T-box transcription factor 1	Homo sapiens	9-12
31548413-10	2019	Our observations suggest that glycine is a multifaceted regulator of d-serine metabolism and implicate both d-serine and glycine in mediating NMDAR synaptic activation at the mature hippocampus through a Phgdh-dependent shuttle mechanism.	Glycine	30-37	3-phosphoglycerate dehydrogenase	Mus musculus	204-209
31548413-10	2019	Our observations suggest that glycine is a multifaceted regulator of d-serine metabolism and implicate both d-serine and glycine in mediating NMDAR synaptic activation at the mature hippocampus through a Phgdh-dependent shuttle mechanism.	Glycine	121-128	3-phosphoglycerate dehydrogenase	Mus musculus	204-209
23412628-5	2013	Inhibition of glycinamide ribonucleotide formyltransferase (GARFTase) was assayed by nucleoside protection assays and in situ GARFTase assays with [(14)C]glycine.	Glycine	154-161	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	Homo sapiens	14-58
31278967-8	2019	Similar to cleavage preferences of matrix metalloproteinases-2, -7, -9 and -12, matrix metalloproteinase-14 prefers small and medium-sized hydrophobic residues including Gly, Ala, Leu and Val at cleavage site P1".	Glycine	170-173	matrix metallopeptidase 14	Homo sapiens	35-107
23412628-5	2013	Inhibition of glycinamide ribonucleotide formyltransferase (GARFTase) was assayed by nucleoside protection assays and in situ GARFTase assays with [(14)C]glycine.	Glycine	154-161	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	Homo sapiens	60-68
31439631-1	2019	GIGYF (Grb10-interacting GYF [glycine-tyrosine-phenylalanine domain]) proteins coordinate with 4EHP (eIF4E [eukaryotic initiation factor 4E] homologous protein), the DEAD (Asp-Glu-Ala-Asp)-box helicase Me31B/DDX6, and mRNA-binding proteins to elicit transcript-specific repression.	Glycine	30-37	eukaryotic translation initiation factor 4E	Homo sapiens	101-106
22961935-3	2013	Herein, we prepared RGDS peptide photocaged either on the Arg-Gly backbone amide nitrogen atom (R[-]GDS) or Asp side chain carboxyl (RG[D]S).	Glycine	62-65	ral guanine nucleotide dissociation stimulator	Homo sapiens	20-24
31439631-1	2019	GIGYF (Grb10-interacting GYF [glycine-tyrosine-phenylalanine domain]) proteins coordinate with 4EHP (eIF4E [eukaryotic initiation factor 4E] homologous protein), the DEAD (Asp-Glu-Ala-Asp)-box helicase Me31B/DDX6, and mRNA-binding proteins to elicit transcript-specific repression.	Glycine	30-37	eukaryotic translation initiation factor 4E	Homo sapiens	108-139
31439631-1	2019	GIGYF (Grb10-interacting GYF [glycine-tyrosine-phenylalanine domain]) proteins coordinate with 4EHP (eIF4E [eukaryotic initiation factor 4E] homologous protein), the DEAD (Asp-Glu-Ala-Asp)-box helicase Me31B/DDX6, and mRNA-binding proteins to elicit transcript-specific repression.	Glycine	30-37	DEAD-box helicase 6	Homo sapiens	208-212
31709057-1	2019	Protein-engineering methods have been exploited to produce a surrogate system for the extracellular neurotransmitter-binding site of a heteromeric human ligand-gated ion channel, the glycine receptor.	Glycine	183-190	glycine receptor alpha 3	Homo sapiens	153-177
23340205-7	2013	Since glycine (at position 30) can readily adopt alpha(L) conformation, G(n) loop plays a dual role in both facilitating loop closure as well as facilitating reorganization/packing of helices required for structural adjustment during dimer formation in the folding of Rop.	Glycine	6-13	opsin 1, long wave sensitive	Homo sapiens	268-271
23246290-7	2013	The missense mutation c.133G&gt;A leads to a glycine to serine substitution and is predicted to disrupt the structure of SNRPE.	Glycine	45-52	small nuclear ribonucleoprotein polypeptide E	Homo sapiens	121-126
31134633-2	2019	Mitochondrial serine hydroxymethyltransferase 1 (SHMT1) is an essential photorespiratory enzyme converting glycine to serine.	Glycine	107-114	serine transhydroxymethyltransferase 1	Arabidopsis thaliana	14-47
23711493-8	2013	As shown in PEPT1 expressing oocytes, Igly-gly without significantly modifying the concentration required for halfmaximal Igly-gly (KM).	Glycine	39-42	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	12-17
31134633-2	2019	Mitochondrial serine hydroxymethyltransferase 1 (SHMT1) is an essential photorespiratory enzyme converting glycine to serine.	Glycine	107-114	serine transhydroxymethyltransferase 1	Arabidopsis thaliana	49-54
23711493-9	2013	Following disruption of carrier insertion with brefeldin A (5 microM) Igly-gly declined similarly fast in Xenopus oocytes expressing PEPT1 with JAK2 and in Xenopus oocytes expressing PEPT1 alone.	Glycine	71-74	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	133-138
23573143-4	2013	The expression level of phosphorylated FAK, Akt, ERK1/2, and Rb was decreased p21 expression while level was increased in WEHI-3 treated with GLY.	Glycine	142-145	mitogen-activated protein kinase 3	Mus musculus	49-55
23573143-6	2013	Moreover, experimental results demonstrated that GLY decreased the protein expression and enzyme activity of MMP-2 and MMP-9.	Glycine	49-52	matrix metallopeptidase 9	Mus musculus	119-124
31387209-7	2019	Our studies demonstrated that SUSD2 is cleaved at its glycine-aspartic acid-proline-histidine (GDPH) amino acid sequence.	Glycine	54-61	sushi domain containing 2	Homo sapiens	30-35
23806011-2	2013	In the first case, a new delta-globin variant, Hb A2-Pierre-Benite [delta83(EF7)Gly Arg; HBD: c.250G&gt;C] is associated with Hb Groene Hart [alpha119(H2)Pro Ser (alpha1); HBA1: c.358C&gt;T], an alpha-thalassemic variant.	Glycine	80-83	hemoglobin subunit alpha 2	Homo sapiens	47-52
31078377-1	2019	Recent work has delineated key differences in the antigen processing and presentation mechanisms underlying HLA-DP alleles encoding glycine at position 84 of the DPbeta chain (DP84GGPM87).	Glycine	132-139	major histocompatibility complex, class II, DP beta 1	Homo sapiens	108-114
23806011-2	2013	In the first case, a new delta-globin variant, Hb A2-Pierre-Benite [delta83(EF7)Gly Arg; HBD: c.250G&gt;C] is associated with Hb Groene Hart [alpha119(H2)Pro Ser (alpha1); HBA1: c.358C&gt;T], an alpha-thalassemic variant.	Glycine	80-83	hemoglobin subunit alpha 1	Homo sapiens	172-176
22893680-7	2012	Expression of the CaM isoform Gly-Ser-His-CaM (GSH-CaM), which has much higher binding affinity than wild-type CaM for RyR1, restored normal CaM binding to RyR2 in both SR and myocytes of failing hearts.	Glycine	30-33	calmodulin-2	Canis lupus familiaris	18-21
22893680-7	2012	Expression of the CaM isoform Gly-Ser-His-CaM (GSH-CaM), which has much higher binding affinity than wild-type CaM for RyR1, restored normal CaM binding to RyR2 in both SR and myocytes of failing hearts.	Glycine	30-33	calmodulin-2	Canis lupus familiaris	42-45
22893680-7	2012	Expression of the CaM isoform Gly-Ser-His-CaM (GSH-CaM), which has much higher binding affinity than wild-type CaM for RyR1, restored normal CaM binding to RyR2 in both SR and myocytes of failing hearts.	Glycine	30-33	calmodulin-2	Canis lupus familiaris	42-45
22893680-7	2012	Expression of the CaM isoform Gly-Ser-His-CaM (GSH-CaM), which has much higher binding affinity than wild-type CaM for RyR1, restored normal CaM binding to RyR2 in both SR and myocytes of failing hearts.	Glycine	30-33	calmodulin-2	Canis lupus familiaris	42-45
22893680-7	2012	Expression of the CaM isoform Gly-Ser-His-CaM (GSH-CaM), which has much higher binding affinity than wild-type CaM for RyR1, restored normal CaM binding to RyR2 in both SR and myocytes of failing hearts.	Glycine	30-33	calmodulin-2	Canis lupus familiaris	42-45
25287634-3	2013	In this study, we clarified the relationship between dysbindin, glutamate, and glycine with in vivo microdialysis methods.	Glycine	79-86	dystrobrevin binding protein 1	Mus musculus	53-62
25287634-9	2013	CONCLUSIONS: These results suggest that dysbindin might modulate glycine and glutamate release in vivo.	Glycine	65-72	dystrobrevin binding protein 1	Mus musculus	40-49
31067009-0	2019	Novel variants and clinical symptoms in four new ALG3-CDG patients, review of the literature, and identification of AAGRP-ALG3 as a novel ALG3 variant with alanine and glycine-rich N-terminus.	Glycine	168-175	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	116-126
23455613-3	2013	GSH is synthesized from glutamate, cysteine, and glycine by the sequential action of Gsh1 (gamma-glutamyl-cysteine synthetase) and Gsh2 (glutathione synthetase) enzymes.	Glycine	49-56	glutathione synthase	Saccharomyces cerevisiae S288C	131-135
23014974-2	2012	Composed of three Ank (ankyrin) repeats and two CAP-Gly (cytoskeleton-associated protein-glycine) domains, CLIP3 may function as a cytoplasmic linker protein that is involved in TGN-endosome dynamics.	Glycine	89-96	CAP-GLY domain containing linker protein 3	Rattus norvegicus	107-112
31067009-0	2019	Novel variants and clinical symptoms in four new ALG3-CDG patients, review of the literature, and identification of AAGRP-ALG3 as a novel ALG3 variant with alanine and glycine-rich N-terminus.	Glycine	168-175	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	122-126
30834435-7	2019	Residues corresponding to Gly-202 and Gly-214 in the related transporter SLC35A1 form a substrate-translocating channel, suggesting that a similar mechanism may be involved in SLC35A2.	Glycine	26-29	solute carrier family 35 member A1	Homo sapiens	73-80
23169997-6	2012	To understand how Lcn2 exploits functional differences between siderophores, isogenic mutants of an Ent(+) Gly-Ent(+) Ybt(+) K. pneumoniae strain were inoculated into Lcn2(+/+) and Lcn2(-/-) mice, and the pattern of pneumonia was examined.	Glycine	107-110	lipocalin 2	Mus musculus	18-22
23627311-4	2013	The most potent analogues had EC50 values of 300 nM and showed over 2-fold potentiation of the response to maximally effective concentrations of glutamate and glycine but had no effect on responses from NMDA receptors containing the GluN2A or GluN2B subunits AMPA, kainate, and GABA or glycine receptors or a variety of other potential targets.	Glycine	159-166	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	243-249
30834435-7	2019	Residues corresponding to Gly-202 and Gly-214 in the related transporter SLC35A1 form a substrate-translocating channel, suggesting that a similar mechanism may be involved in SLC35A2.	Glycine	26-29	solute carrier family 35 member A2	Homo sapiens	176-183
30834435-7	2019	Residues corresponding to Gly-202 and Gly-214 in the related transporter SLC35A1 form a substrate-translocating channel, suggesting that a similar mechanism may be involved in SLC35A2.	Glycine	38-41	solute carrier family 35 member A1	Homo sapiens	73-80
31070104-2	2019	Based on evidence from the literature, the atheroprotective association with carbamoyl-phosphate synthase 1 could be mediated by the strong genetic effect of this locus on increased circulating glycine levels.	Glycine	194-201	carbamoyl-phosphate synthase 1	Homo sapiens	77-107
23427147-3	2013	Another TARDBP ortholog, tardbpl, in zebrafish is shown to encode a Tardbp-like protein which is truncated compared with Tardbp itself and lacks part of the C-terminal glycine-rich domain (GRD).	Glycine	168-175	TAR DNA binding protein a	Danio rerio	25-32
22986737-3	2012	This study examined the predictive and prognostic value of a single nucleotide polymorphism substituting an arginine (R) for glycine (G) in codon 388 of the FGFR4 transmembrane domain.	Glycine	125-132	fibroblast growth factor receptor 4	Homo sapiens	157-162
23146735-4	2012	RESULTS: A heterozygous 743G&gt;A mutation was found in the patient and his mother, resulting in the substitution of glycine (G) by arginine (R) in codon 222(G222R) in the putative membrane-spanning domain in human G6Pase, but not in his father and his sister.	Glycine	117-124	glucose-6-phosphatase catalytic subunit 1	Homo sapiens	215-221
31113850-0	2019	mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-beta1-induced collagen biosynthesis.	Glycine	77-84	CREB regulated transcription coactivator 1	Mus musculus	0-6
23757024-3	2013	AtGLR3.4, a plant iGluR homolog from Arabidopsis thaliana, has ion channel activity and is gated by asparagine, serine, and glycine.	Glycine	124-131	glutamate receptor 3.4	Arabidopsis thaliana	0-8
23115192-5	2012	The physiological function of appoptosin is to transport/exchange glycine/5-amino-levulinic acid across the mitochondrial membrane for heme synthesis.	Glycine	66-73	solute carrier family 25 member 38	Homo sapiens	30-40
23562395-3	2013	We used NMR and other biophysical methods to reveal that S. cerevisiae Rpt6"s C-terminal domain undergoes dynamic helix-coil transitions enabled by helix-destabilizing glycines within its two most C-terminal alpha helices.	Glycine	168-176	proteasome regulatory particle base subunit RPT6	Saccharomyces cerevisiae S288C	71-75
23562395-5	2013	Loss of Rpt6"s partially unfolded state by glycine substitution (Rpt6 G360,387A) disrupts holoenzyme formation in vitro, an effect enhanced by Rpn14.	Glycine	43-50	proteasome regulatory particle base subunit RPT6	Saccharomyces cerevisiae S288C	8-12
30779965-4	2019	In this study, we focused on glycine decarboxylase (GLDC), a key enzyme in the glycine cleavage system that regulates glycolysis and methylglyoxal production in cancer.	Glycine	29-36	glycine decarboxylase	Homo sapiens	52-56
23562395-5	2013	Loss of Rpt6"s partially unfolded state by glycine substitution (Rpt6 G360,387A) disrupts holoenzyme formation in vitro, an effect enhanced by Rpn14.	Glycine	43-50	proteasome regulatory particle base subunit RPT6	Saccharomyces cerevisiae S288C	65-69
30988181-4	2019	In Ndp KO retinas, we observe gene expression responses consistent with hypoxia in Muller glia and retinal neurons, and we find a metabolic shift that combines reduced flux through the TCA cycle with increased synthesis of serine, glycine, and glutathione.	Glycine	231-238	Norrie disease (pseudoglioma) (human)	Mus musculus	3-6
23650557-2	2013	Mutations in the human GlyT2 gene (SLC6A5) that cause deficient glycine transport or defective GlyT2 trafficking are the second most common cause of hyperekplexia or startle disease.	Glycine	64-71	solute carrier family 6 member 5	Homo sapiens	23-28
23650557-2	2013	Mutations in the human GlyT2 gene (SLC6A5) that cause deficient glycine transport or defective GlyT2 trafficking are the second most common cause of hyperekplexia or startle disease.	Glycine	64-71	solute carrier family 6 member 5	Homo sapiens	35-41
23650557-8	2013	Co-expression of CNX and a fully non-glycosylated mutant rescues glycine transport but not mutant surface expression.	Glycine	65-72	calnexin	Homo sapiens	17-20
30511276-4	2019	Therefore, the aim of this study was to investigate the impact of the elastin-derived valine-glycine-valine-alanine-proline-glycine (VGVAPG) peptide on Ppargamma and beta-galactosidase (beta-Gal) expression in mouse cortical astrocytes in vitro.	Glycine	93-100	peroxisome proliferator activated receptor gamma	Mus musculus	152-161
23434137-4	2013	In addition, peptides were designed with different levels of flexibility by introducing glycine (Gly) residues into the L-2-amino-3-guanidinopropionic acid (Agp) oligomers.	Glycine	88-95	immunoglobulin kappa variable 3-15	Homo sapiens	120-123
23434137-4	2013	In addition, peptides were designed with different levels of flexibility by introducing glycine (Gly) residues into the L-2-amino-3-guanidinopropionic acid (Agp) oligomers.	Glycine	97-100	immunoglobulin kappa variable 3-15	Homo sapiens	120-123
23089362-7	2013	Synaptic GluN2A-containing and extrasynaptic GluN2B-containing NMDARs have different co-agonists: d-serine for synaptic NMDARs and glycine for extrasynaptic NMDARs.	Glycine	131-138	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	45-51
30926858-4	2019	We observed the effects of individual and combined mutations of the CD loop and Phe106 that conferred to Ngb higher CO binding velocities, which we correlate with the following structural observations: the mutant F106A shows, upon CO binding, a reduced heme sliding hindrance, with the heme present in a peculiar double conformation, whereas in the CD loop mutant "Gly-loop", the original network of interactions between the loop and the heme was abolished, enhancing binding via facilitated gating out of the distal His64.	Glycine	365-368	neuroglobin	Mus musculus	105-108
23384347-4	2013	In the present study, we demonstrate for the first time that TfR1-NTF is subject to regulated intramembrane proteolysis and, using MALDI-TOF-TOF-MS, we have identified the cleavage site as being located C-terminal from Gly-84.	Glycine	219-222	transferrin receptor	Homo sapiens	61-65
30830484-8	2019	The neuraminidase inhibitor oseltamivir created considerable downregulation of energy center metabolites (glucose, sucrose, glycine and glutamine), which generated high levels of branched amino acids.	Glycine	124-131	neuraminidase 1	Homo sapiens	4-17
23321419-6	2013	Examination of transgenic plants showed that a glycine-to-threonine substitution gave the strongest antagonistic effect in the wild type, in which over 70% of transgenic lines showed the clv3-like phenotype.	Glycine	47-54	CLAVATA3	Arabidopsis thaliana	187-191
30341973-9	2019	Hematoxylin-eosin staining and immunostaining for single-stranded DNA and activated caspase 3 showed less sinusoidal dilatation and tissue damage in livers treated with dialysis and glycine.	Glycine	182-189	caspase 3	Rattus norvegicus	84-93
24371822-6	2013	The ADRB1 gene showed a statistically significant association with high-risk atherogenic index, OR = 2.94 (IC 95% 1.64-5.24; P &lt; 0.0001) for the Arg/Gly variant, under the dominant model an OR = 2.96 (IC 95% 1.67-5.25; P &lt; 0.0001), and under the Log additive model an OR = 2.52 (IC 95% 1.54-4.15; P &lt; 0.0001).	Glycine	152-155	adrenoceptor beta 1	Homo sapiens	4-9
29859229-3	2019	One of the most frequent causes of hyperekplexia are mutations in the SLC6A5 gene, encoding the neuronal glycine transporter 2 (GlyT2), a key component of inhibitory glycinergic presynapses involved in synaptic glycine recycling though sodium and chloride-dependent co-transport.	Glycine	105-112	solute carrier family 6 member 5	Homo sapiens	70-76
23586032-4	2013	When seeded with vascular smooth muscle cells (VSMCs), the Gly- or PEG-grafted samples increased mainly the spreading and concentration of focal adhesion proteins talin and vinculin in these cells.	Glycine	59-62	vinculin	Homo sapiens	173-181
29859229-3	2019	One of the most frequent causes of hyperekplexia are mutations in the SLC6A5 gene, encoding the neuronal glycine transporter 2 (GlyT2), a key component of inhibitory glycinergic presynapses involved in synaptic glycine recycling though sodium and chloride-dependent co-transport.	Glycine	105-112	solute carrier family 6 member 5	Homo sapiens	128-133
29704198-1	2019	Galectin-3 (Gal-3) is a chimeric protein structurally composed of unusual tandem repeats of proline and short glycine-rich segments fused onto a carbohydrate recognition domain.	Glycine	110-117	galectin 3	Homo sapiens	0-17
23548307-2	2013	For birch pollen (BP)-allergic patients, the Bet v 1 homologous allergen Gly m 4 is also a potential trigger of generalized severe reactions upon soy consumption.	Glycine	73-76	delta/notch like EGF repeat containing	Homo sapiens	45-48
23247503-2	2013	The N-terminal region of hnRNP A1, also named unwinding protein 1 (UP1), is composed of two closely related RNA recognition motifs (RRM), and is followed by a C-terminal glycine rich region.	Glycine	170-177	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	25-33
30168177-6	2018	Visual analysis of the GluN2B structure with the E413G mutation modeled suggests that replacement of Glu with Gly at this position increases solvent access to the ligand-binding domain.	Glycine	110-113	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	23-29
23247503-2	2013	The N-terminal region of hnRNP A1, also named unwinding protein 1 (UP1), is composed of two closely related RNA recognition motifs (RRM), and is followed by a C-terminal glycine rich region.	Glycine	170-177	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	46-65
23247503-2	2013	The N-terminal region of hnRNP A1, also named unwinding protein 1 (UP1), is composed of two closely related RNA recognition motifs (RRM), and is followed by a C-terminal glycine rich region.	Glycine	170-177	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	67-70
23472094-1	2013	This paper describes a biophysical investigation of residual mobility in complexes of bovine carbonic anhydrase II (BCA) and para-substituted benzenesulfonamide ligands with chains of 1-5 glycine subunits, and explains the previously observed increase in entropy of binding with chain length.	Glycine	188-195	carbonic anhydrase 2	Bos taurus	93-114
30301779-1	2018	Previous studies have shown that TM9SF4 interacts with glycine-rich transmembrane domains (TMDs) and promotes their surface localization, presumably by escorting them along the secretory pathway.	Glycine	55-62	transmembrane 9 superfamily member 4	Homo sapiens	33-39
30255931-9	2018	Furthermore, two patients on VPA polytherapy developed acute pancreatitis, and two pediatric patients with heterozygous p.Q1236H variants and mutations in IQSEC2 and GLDC, respectively, had elevated levels of VPA metabolites in urine, elevated plasma glycine, and/or increased acylglycine excretion.	Glycine	251-258	glycine decarboxylase	Homo sapiens	166-170
30149018-1	2018	The glucagon-like peptide 1 receptor (GLP-1R) can be activated by a number of endogenous peptide hormones, including extended, processed, glycine extended and carboxy-terminally amidated versions of glucagon-like peptide 1 (GLP-1).	Glycine	138-145	glucagon like peptide 1 receptor	Homo sapiens	4-36
30149018-1	2018	The glucagon-like peptide 1 receptor (GLP-1R) can be activated by a number of endogenous peptide hormones, including extended, processed, glycine extended and carboxy-terminally amidated versions of glucagon-like peptide 1 (GLP-1).	Glycine	138-145	glucagon like peptide 1 receptor	Homo sapiens	38-44
23105112-7	2012	Similarly, mutation of the residues alanine 262 and glycine 266 of an AXXXG dimerization motif flanking the gamma-secretase cleavage site within the p75(NTR) transmembrane domain alters the orientation of the domain and inhibits gamma-secretase cleavage of p75(NTR).	Glycine	52-59	neurotensin receptor 1	Homo sapiens	149-157
30122033-3	2018	The domain organization of hnRNP F/H proteins is modular, consisting of N-terminal tandem quasi-RNA recognition motifs (F/HqRRM1,2) and a third C-terminal qRRM3 embedded between glycine-rich repeats.	Glycine	178-185	heterogeneous nuclear ribonucleoprotein F	Homo sapiens	27-34
23194061-2	2012	Previously, we found that human sperm tails contain trophinin, bystin and tastin proteins, and that trophinin-binding GWRQ (glycine, tryptophan, arginine, glutamine) peptide enhanced motility of human sperm.	Glycine	124-131	trophinin	Mus musculus	100-109
30275690-2	2018	Secondary analyses were performed to examine the effect of background long-acting beta2-agonist (LABA) use on the efficacy and safety of nebulized GLY.	Glycine	147-150	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	82-87
23027862-5	2012	Also, we have found that a recombinant protein consisting of C2GnT1 CT(1-16)-Leu(17-32)-Gly(33-42)-GFP is localized to the Golgi although the same construct with mutated CT (AAAAA(9)) is not.	Glycine	88-91	glucosaminyl (N-acetyl) transferase 1	Homo sapiens	61-67
30140255-4	2018	The in vitro results indicated that Pro-Gly, but not Pro plus Gly, promoted the expression and secretion of IGF-1 in HepG2.	Glycine	40-43	insulin-like growth factor 1	Mus musculus	108-113
22971346-3	2012	The biologic analyses revealed an oncogenic importance for both polymorphic alleles, but FGFR4(gly) was the stronger inducer of tumor growth, whereas FGFR4(arg) was the stronger inducer of migration.	Glycine	95-98	fibroblast growth factor receptor 4	Homo sapiens	89-94
22971346-4	2012	An evaluation of clinical specimens revealed that FGFR4 was upregulated in 20/71 patients independent of gly(388)arg status.	Glycine	105-108	fibroblast growth factor receptor 4	Homo sapiens	50-55
30140255-9	2018	In agreement with the in vitro results, the in vivo findings demonstrated that Pro-Gly, but not Pro plus Gly, stimulated the expression and secretion of IGF-1 and activated JAK2/STAT5 signaling pathway in the liver of mice injected with Pro-Gly or Pro+Gly acutely or chronically.	Glycine	83-86	insulin-like growth factor 1	Mus musculus	153-158
28579060-4	2018	The disease owes its severity to the fact that LADH is the common E3 subunit of the alpha-ketoglutarate (KGDHc), pyruvate (PDHc), and branched-chain alpha-keto acid dehydrogenase complexes and is also part of the glycine cleavage system, hence the malfunctioning of LADH simultaneously incapacitates several central metabolic pathways.	Glycine	213-220	dihydrolipoamide dehydrogenase	Homo sapiens	66-68
22350545-6	2012	The amino acid substitution of a glycine to arginine resulted in a markedly reduced steady-state level of the IVD protein, which explains the nearly complete lack of IVD enzyme activity as assessed in fibroblast homogenates.	Glycine	33-40	isovaleryl-CoA dehydrogenase	Homo sapiens	110-113
22350545-6	2012	The amino acid substitution of a glycine to arginine resulted in a markedly reduced steady-state level of the IVD protein, which explains the nearly complete lack of IVD enzyme activity as assessed in fibroblast homogenates.	Glycine	33-40	isovaleryl-CoA dehydrogenase	Homo sapiens	166-169
30265352-6	2018	However, considerable binding affinity, and, consequently, toxin-neutralizing activity of A9 is mediated by an unusual CDR2 containing five consecutive Gly residues that interact with alpha-helix B (82 A2), a known neutralizing hotspot on RTA.	Glycine	152-155	cerebellar degeneration related protein 2	Homo sapiens	119-123
23006328-3	2012	Glycine-rich C-terminal fragments derived from human cytokeratin 6A were identified in bactericidal lysate fractions of human corneal epithelial cells.	Glycine	0-7	keratin 6A	Homo sapiens	53-67
22796215-4	2012	The protective effect of glycine was associated with reduction of terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) positive cells, deactivation of phosphor-JNK, inhibition of caspase-3 cleavage, down-regulation of FasL/Fas, and up-regulation of bcl-2 and bcl-2/bax in the mouse I/R penumbra.	Glycine	25-32	Fas ligand (TNF superfamily, member 6)	Mus musculus	241-245
30265352-7	2018	Removal of a single Gly residue from the penta-glycine stretch in CDR2 reduced A9"s binding affinity by 10-fold and eliminated toxin-neutralizing activity.	Glycine	20-23	cerebellar degeneration related protein 2	Homo sapiens	66-70
30265352-8	2018	Computational modeling indicates that removal of a Gly from CDR2 does not perturb contact with RTA per se, but results in the loss of an intramolecular hydrogen bond network involved in stabilizing CDR2 in the unbound state.	Glycine	51-54	cerebellar degeneration related protein 2	Homo sapiens	60-64
30265352-8	2018	Computational modeling indicates that removal of a Gly from CDR2 does not perturb contact with RTA per se, but results in the loss of an intramolecular hydrogen bond network involved in stabilizing CDR2 in the unbound state.	Glycine	51-54	cerebellar degeneration related protein 2	Homo sapiens	198-202
29925909-2	2018	Here, we show that in monolayer cancer cell-line cultures, the expression of the five metabolic enzymes of serine-glycine synthesis (SGS), including its rate-limiting enzyme, phosphoglycerate dehydrogenase (PHGDH), displays stochastic cell-to-cell variation.	Glycine	114-121	phosphoglycerate dehydrogenase	Homo sapiens	175-205
22993508-10	2012	Roughly at the middle of the S6 there exists a highly conserved glycine residue and a tandem proline motif that seem to fulfill the role of a gating hinge which allows for tilting/swiveling/rotations of the post-hinge S6 segment.	Glycine	64-71	ribosomal protein S6	Homo sapiens	29-31
22993508-10	2012	Roughly at the middle of the S6 there exists a highly conserved glycine residue and a tandem proline motif that seem to fulfill the role of a gating hinge which allows for tilting/swiveling/rotations of the post-hinge S6 segment.	Glycine	64-71	ribosomal protein S6	Homo sapiens	218-220
23554770-6	2012	Importantly, administration of glycine significantly inhibited apoptosis in post-ischemia-reperfusion myocardium, which was accompanied by suppression of phosphorylated p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase, as well as the Fas ligand.	Glycine	31-38	Fas ligand	Rattus norvegicus	252-262
29925909-2	2018	Here, we show that in monolayer cancer cell-line cultures, the expression of the five metabolic enzymes of serine-glycine synthesis (SGS), including its rate-limiting enzyme, phosphoglycerate dehydrogenase (PHGDH), displays stochastic cell-to-cell variation.	Glycine	114-121	phosphoglycerate dehydrogenase	Homo sapiens	207-212
29928487-8	2018	Nucleolin directly bound to TRA2beta4 exon 2 via the glycine/arginine-rich (GAR) domain.	Glycine	53-60	nucleolin	Homo sapiens	0-9
29989088-8	2018	We herein report 4 novel inhibitor candidates of Asp-Ile-Phe, Asp-Ile-Tyr, Asp-Ile-Lys and Hser-Gly-Phe with high potency and selectivity binding to MMP-2, as well as 6 novel inhibitor candidates of Chg-Ile-Ile, Chg-Ile-Leu, Chg-Ile-Glu, Chg-Ile-Met, Chg-Val-Ile and Chg-Val-Leu selectively binding to MMP-7.	Glycine	96-99	matrix metallopeptidase 2	Homo sapiens	149-154
22915106-0	2012	PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.	Glycine	84-91	protein interacting with PRKCA 1	Rattus norvegicus	0-5
22915106-7	2012	In contrast, GluA2 is restricted from trafficking to the cell surface by a glycine-induced increase in PICK1-GluA2 binding on endosomal compartments.	Glycine	75-82	protein interacting with PRKCA 1	Rattus norvegicus	103-108
22915106-9	2012	These results define a PICK1-dependent mechanism that underlies transient alterations in the subunit composition and calcium permeability of synaptic AMPARs that is important during the early phase after stimulation with glycine and therefore is likely to be important during the expression of LTP.	Glycine	221-228	protein interacting with PRKCA 1	Rattus norvegicus	23-28
29481666-6	2018	In addition to the seven novel gene associations, we identified five independent signals at established amino acid loci, including two rare variant signals at GLDC (rs138640017, MAF=0.95%, Pconditional = 5.8x10-40) with glycine levels and HAL (rs141635447, MAF = 0.46%, Pconditional = 9.4x10-11) with histidine levels.	Glycine	220-227	glycine decarboxylase	Homo sapiens	159-163
29681798-8	2018	We observed the most prominent effect when residues GluN1(L657) and GluN2B(I655) were deleted or altered to glycine.	Glycine	108-115	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	68-79
29576319-2	2018	Here, we show that the CAP-Gly and coiled-coil domains of Bik1 interact with the C-terminal ETF peptide of Bim1 and the C-terminal tail region of Stu2, respectively.	Glycine	27-30	Bik1p	Saccharomyces cerevisiae S288C	58-62
22440150-3	2012	Poly(acrylic acid) hydrogels were synthesized by UV polymerization and pendant MMP-2 sensitive peptides (Gly-Pro-Leu-Gly-Val-Arg-Gly-Lys) conjugated throughout using EDC/sulfo-NHS chemistry.	Glycine	105-108	matrix metallopeptidase 2	Homo sapiens	79-84
22261077-1	2012	Non ketotic hyperglycinemia is a rare inborn error of glycine metabolism due to deficient activity of glycine cleavage system, a multienzymatic complex consisting of four protein subunits: the P-protein, the H-protein, the T-protein and the L-protein.	Glycine	17-24	OCA2 melanosomal transmembrane protein	Homo sapiens	193-202
29576319-3	2018	The crystal structures of the CAP-Gly domain of Bik1 (Bik1CG) alone and in complex with an ETF peptide revealed unique, functionally relevant CAP-Gly elements, establishing Bik1CG as a specific C-terminal phenylalanine recognition domain.	Glycine	34-37	Bik1p	Saccharomyces cerevisiae S288C	48-52
22920190-5	2012	The inhibition by non-cytoxic doses of GLY of VSMCs migration was through its negative regulatory effects on phosphorylated ERK1/2, PI3K/AKT, and FAK.	Glycine	39-42	mitogen activated protein kinase 3	Rattus norvegicus	124-130
29556099-4	2018	A structure-guided mutagenesis screen of the TRPC3 pore domain unveiled a single glycine residue behind the selectivity filter (G652) that is exposed to lipid through a subunit-joining fenestration.	Glycine	81-88	transient receptor potential cation channel subfamily C member 3	Homo sapiens	45-50
22707719-3	2012	ADAMTS5 cleaves Glu(373)-Ala(374) and Glu(1480)-Gly(1481) bonds in bovine aggrecan but does not cleave VWF.	Glycine	48-51	ADAM metallopeptidase with thrombospondin type 1 motif 5	Bos taurus	0-7
22453920-5	2012	MOCS2A and URM1 are beta-grasp fold proteins that contain a highly conserved C-terminal double glycine motif.	Glycine	95-102	ubiquitin related modifier 1	Homo sapiens	11-15
22453920-7	2012	Deletion of the C-terminal glycine of either MOCS2A or URM1 resulted in a loss of interaction with MOCS3.	Glycine	27-34	ubiquitin related modifier 1	Homo sapiens	55-59
22593944-8	2004	The peptide Gly-Pro-Leu-Gly-Val-Arg-NH2 (GPLGVR) was found to be a MMP2/9 substrate and is cleaved between the Gly (G) and Val (V) residues (9).	Glycine	12-15	matrix metallopeptidase 2	Homo sapiens	67-73
29549925-8	2018	By logistic regression analysis, high fasting plasma glucose, smoking, high triglyceride and the Gly/Gly polymorphism in Arg389Gly ADRB1 all emerged as independent risk factors for hypertension.	Glycine	97-100	adrenoceptor beta 1	Homo sapiens	131-136
22593948-8	2004	The peptide Gly-Pro-Leu-Gly-Val-Arg-NH2 (GPLGVR) was found to be a MMP2/9 substrate and is cleaved between the Gly (G) and Val (V) residues (9).	Glycine	12-15	matrix metallopeptidase 2	Homo sapiens	67-73
29549925-8	2018	By logistic regression analysis, high fasting plasma glucose, smoking, high triglyceride and the Gly/Gly polymorphism in Arg389Gly ADRB1 all emerged as independent risk factors for hypertension.	Glycine	101-104	adrenoceptor beta 1	Homo sapiens	131-136
23012891-5	2012	Among the female subjects, there were also significant relationships between SD and 49Ser/Gly in ADRB1, and C (cooperativeness) and 389Arg/Gly in ADRB1.	Glycine	139-142	adrenoceptor beta 1	Homo sapiens	146-151
29549925-10	2018	CONCLUSIONS: The results demonstrate that Gly/Gly polymorphism in Arg389Gly ADRB1 was an independent risk factor together with high fasting plasma glucose, smoking and high triglyceride; moreover, the patients who carried the Gly389Gly genotype had a significantly improved metoprolol antihypertensive effect than those with ADRB1.	Glycine	42-45	adrenoceptor beta 1	Homo sapiens	76-81
29549925-10	2018	CONCLUSIONS: The results demonstrate that Gly/Gly polymorphism in Arg389Gly ADRB1 was an independent risk factor together with high fasting plasma glucose, smoking and high triglyceride; moreover, the patients who carried the Gly389Gly genotype had a significantly improved metoprolol antihypertensive effect than those with ADRB1.	Glycine	42-45	adrenoceptor beta 1	Homo sapiens	325-330
22452443-2	2012	The RGD motif {cyclic(Arg-Gly-Asp-D-Tyr-Asp)} was coupled to [Cys(3,4,10), D-Phe(7), Arg(11)]alpha-MSH(3-13) {(Arg(11))CCMSH} through a neutral glycine linker to eliminate the positively charged amino side chain of the Lys linker or without a linker to delete the Lys linker.	Glycine	144-151	pro-opiomelanocortin-alpha	Mus musculus	93-102
29549925-10	2018	CONCLUSIONS: The results demonstrate that Gly/Gly polymorphism in Arg389Gly ADRB1 was an independent risk factor together with high fasting plasma glucose, smoking and high triglyceride; moreover, the patients who carried the Gly389Gly genotype had a significantly improved metoprolol antihypertensive effect than those with ADRB1.	Glycine	46-49	adrenoceptor beta 1	Homo sapiens	76-81
22416082-7	2012	In addition, treatment with h(Gly(2))GLP-2 significantly increased neurotensin and ghrelin mRNA transcript levels by 50 and 95%, respectively, at 24 h after treatment in protein kinase A-dependent manner.	Glycine	30-33	ghrelin	Mus musculus	83-90
22610100-0	2012	Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor.	Glycine	192-199	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	16-20
22829704-3	2012	Integrin-ECM interaction was inhibited with anti-beta1-integrin monoclonal antibody (mAb) or RGDS (Arg-Gly-Asp-Ser).	Glycine	103-106	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	93-97
28850807-1	2018	Milk-fat globule epidermal growth factor (EGF) 8 protein (MFGE8), also known as lactadherin, promotes cell adhesion in an Arg-Gly-Asp (RGD)-dependent modus via integrins.	Glycine	126-129	lactadherin	Equus caballus	58-63
29440987-6	2018	Pathway and enrichment analysis of non-targeted primary metabolite profiles from Sirt5-/- cortex revealed alterations in several pathways including purine metabolism (urea, adenosine, adenine, xanthine), nitrogen metabolism (glutamic acid, glycine), and malate-aspartate shuttle (malic acid, glutamic acid).	Glycine	240-247	sirtuin 5	Mus musculus	81-86
22633639-2	2012	The majority of cases are caused by mutations in P-protein, one of the four components of the glycine cleavage enzyme, glycine decarboxylase.	Glycine	94-101	OCA2 melanosomal transmembrane protein	Homo sapiens	49-58
22633639-2	2012	The majority of cases are caused by mutations in P-protein, one of the four components of the glycine cleavage enzyme, glycine decarboxylase.	Glycine	94-101	glycine decarboxylase	Homo sapiens	119-140
22339672-4	2012	Glu/Gly applications decreased pH(i) to 6.1 and induced intracellular Zn2+ release in a Ca2+-dependent manner, as expected.	Glycine	4-7	glucose-6-phosphate isomerase	Homo sapiens	31-36
22339672-9	2012	Inhibiting the mechanisms responsible for the Ca2+-dependent pH(i) drop (plasmalemmal Ca2+ pump and mitochondria) counteracted the Glu/Gly-induced intracellular Zn2+ release.	Glycine	135-138	glucose-6-phosphate isomerase	Homo sapiens	61-66
29086036-2	2018	Prominent examples include mutations in the transporters for dopamine (DAT, SLC6A3), for creatine (CT1, SLC6A8), and for glycine (GlyT2, SLC6A5), which result in infantile dystonia, mental retardation, and hyperekplexia, respectively.	Glycine	121-128	solute carrier family 6 member 5	Homo sapiens	130-135
22127737-8	2012	Homology modeling identified a residue specific to ASPGB1, Phe(162), preceding the variable loop, whose side chain is located in proximity to the beta-carboxylate group of the product aspartate, and to Gly(246), a residue participating in an oxyanion hole which stabilizes a negative charge forming on the side chain oxygen of asparagine during catalysis.	Glycine	202-205	N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein	Arabidopsis thaliana	51-57
21909137-0	2012	Integrity of mTORC2 is dependent on the rictor Gly-934 site.	Glycine	47-50	CREB regulated transcription coactivator 2	Mus musculus	13-19
22617883-3	2012	Nucleolin"s implication in disease is linked to its ability to associate with target RNAs via its four RNA-binding domains and its arginine/glycin-rich domain.	Glycine	140-146	nucleolin	Homo sapiens	0-9
29086036-2	2018	Prominent examples include mutations in the transporters for dopamine (DAT, SLC6A3), for creatine (CT1, SLC6A8), and for glycine (GlyT2, SLC6A5), which result in infantile dystonia, mental retardation, and hyperekplexia, respectively.	Glycine	121-128	solute carrier family 6 member 5	Homo sapiens	137-143
22474253-7	2012	NR1 subunit of NMDA receptor antagonist 7-chlorokynurenic acid, adenoviral injection of NR1 short hairpin RNA (shRNA), and hepatic vagotomy also nullified glycine"s effect.	Glycine	155-162	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	0-3
22385159-9	2012	Replacing Asp-653, Asp-706, and Asp-708 simultaneously with glycine in the C2 domain of PLC delta1 leads to a complete and selective loss of the stimulation and binding by PS.	Glycine	60-67	phospholipase C delta 1	Homo sapiens	88-98
29226620-7	2017	Glycine conjugate of OCA increased mRNA levels of FXR target genes in Caco-2 cells, FGF-19, SHP, OSTalpha/beta, and IBABP, but not ASBT, in a concentration-dependent manner, while glycine conjugate of UDCA had no effect on the expression of these genes.	Glycine	0-7	nuclear receptor subfamily 1 group H member 4	Homo sapiens	50-53
22132725-3	2012	In contrast, neuronal GLYT2 supplies glycine to the presynaptic terminal with a 3:1:1 stoichiometry.	Glycine	37-44	solute carrier family 6 member 5	Homo sapiens	22-27
22474253-7	2012	NR1 subunit of NMDA receptor antagonist 7-chlorokynurenic acid, adenoviral injection of NR1 short hairpin RNA (shRNA), and hepatic vagotomy also nullified glycine"s effect.	Glycine	155-162	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	88-91
22474253-9	2012	CONCLUSIONS: Molecular and pharmacological inhibition of the NR1-containing NMDA receptors in the DVC negated the ability of glycine to inhibit hepatic secretion of VLDL-TG in vivo.	Glycine	125-132	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	61-64
21373768-9	2012	Glycine treatment suppressed these apoptotic events, signifying its protective role in Hg-induced hepatocyte apoptosis as referred by reduction of p38, JNK and ERK MAPK signaling pathways.	Glycine	0-7	mitogen-activated protein kinase 14	Mus musculus	147-150
22037294-7	2012	This method was used to determine the concentration-dependent increases in D-Ser and associated EC50 values produced by L-Ser and the concentration-dependent decreases in d-Ser and associated IC50 values produced by glycine, a competitive inhibitor of serine racemase (SR).	Glycine	216-223	serine racemase	Homo sapiens	252-267
29226620-7	2017	Glycine conjugate of OCA increased mRNA levels of FXR target genes in Caco-2 cells, FGF-19, SHP, OSTalpha/beta, and IBABP, but not ASBT, in a concentration-dependent manner, while glycine conjugate of UDCA had no effect on the expression of these genes.	Glycine	0-7	fibroblast growth factor 19	Homo sapiens	84-90
22542187-0	2012	The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini.	Glycine	20-23	Dynactin 1, p150 subunit	Drosophila melanogaster	4-8
29226620-7	2017	Glycine conjugate of OCA increased mRNA levels of FXR target genes in Caco-2 cells, FGF-19, SHP, OSTalpha/beta, and IBABP, but not ASBT, in a concentration-dependent manner, while glycine conjugate of UDCA had no effect on the expression of these genes.	Glycine	0-7	nuclear receptor subfamily 0 group B member 2	Homo sapiens	92-95
22542187-0	2012	The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini.	Glycine	20-23	Dynactin 1, p150 subunit	Drosophila melanogaster	9-14
29226620-7	2017	Glycine conjugate of OCA increased mRNA levels of FXR target genes in Caco-2 cells, FGF-19, SHP, OSTalpha/beta, and IBABP, but not ASBT, in a concentration-dependent manner, while glycine conjugate of UDCA had no effect on the expression of these genes.	Glycine	180-187	nuclear receptor subfamily 1 group H member 4	Homo sapiens	50-53
22542187-4	2012	Disruption of the p150(Glued) CAP-Gly domain in neurons causes a specific disruption of vesicle trafficking at terminal boutons (TBs), the distal-most ends of synapses.	Glycine	34-37	Dynactin 1, p150 subunit	Drosophila melanogaster	18-22
22542187-4	2012	Disruption of the p150(Glued) CAP-Gly domain in neurons causes a specific disruption of vesicle trafficking at terminal boutons (TBs), the distal-most ends of synapses.	Glycine	34-37	Dynactin 1, p150 subunit	Drosophila melanogaster	23-28
22071172-1	2012	Glycine conjugation, a phase II detoxification process, is catalyzed by glycine N-acyltransferase (GLYAT; E.C.	Glycine	0-7	glycine N-acyltransferase	Bos taurus	72-97
28872880-8	2017	Furthermore, the study also permitted the identification of ten novel prospective allosteric sites named NP1 to NP10, involving in most of the cases protein structural elements that control kinase activation including the activation loop, the catalytic loop, the alphaC helix, the L16 loop, and the glycine-rich loop.	Glycine	299-306	neuropilin 1	Homo sapiens	105-108
22071172-1	2012	Glycine conjugation, a phase II detoxification process, is catalyzed by glycine N-acyltransferase (GLYAT; E.C.	Glycine	0-7	glycine N-acyltransferase	Bos taurus	99-104
28949522-2	2017	Two peptides CP++ and sCP++ are designed with a sequence comprising a central block (Pro-Hyp-Gly) and two positively charged domains (Pro-Arg-Gly) at both N- and C-termini.	Glycine	93-96	urocortin 3	Homo sapiens	22-25
21935946-9	2012	The fraction of GABA+ boutons decreased by 86% and the fraction of GABA+/Gly+ boutons increased by 200% from P11 to P31, suggesting a switch from GABA+ to GABA+/Gly+ phenotype.	Glycine	73-76	ATPase H+ transporting V1 subunit E1	Rattus norvegicus	116-119
22354986-7	2012	The glycine/arginine-rich C terminus of nucleolin is required for binding, and the four RNA recognition motif domains are included in the isoform that blocks SSAT translation.	Glycine	4-11	nucleolin	Homo sapiens	40-49
22371326-9	2012	The overall induction of AOX in wild-type roots correlated with accumulation of glycine, serine, leucine, lysine, and other amino acids.	Glycine	80-87	alternative oxidase 2	Arabidopsis thaliana	25-28
28570395-11	2017	This possibility is intriguing because the CNV covers GLDC, which encodes glycine dehydrogenase that binds to glycine, a co-agonist at N-methyl-D-aspartate glutamate receptors, and is involved in glutamatergic neurotransmission.	Glycine	74-81	glycine decarboxylase	Homo sapiens	54-58
22366005-1	2012	OBJECTIVE: To obtain a specific antagonist of CXCR4, SDF-1P2G54 by mutating SDF-1 second proline (P) into glycin (G) and removing the alpha-helix of its C-terminal.	Glycine	106-112	C-X-C motif chemokine ligand 12	Homo sapiens	53-58
22354986-7	2012	The glycine/arginine-rich C terminus of nucleolin is required for binding, and the four RNA recognition motif domains are included in the isoform that blocks SSAT translation.	Glycine	4-11	spermidine/spermine N1-acetyltransferase 1	Homo sapiens	158-162
22297112-5	2012	The substitution of Gly with Ala significantly enhanced the melanoma uptake of (99m)Tc-RAD-Lys-(Arg(11))CCMSH compared to (99m)Tc-RGD-Lys-(Arg(11))CCMSH in B16/F1 melanoma-bearing C57 mice, providing a new insight into the design of alpha-MSH peptides for melanoma targeting.	Glycine	20-23	pro-opiomelanocortin-alpha	Mus musculus	233-242
22438917-5	2012	In addition, GlyRS2 (the enzyme encoded by GRS2) had a higher protein stability and a lower K(M) value for yeast tRNA(Gly) under heat shock conditions than under normal conditions.	Glycine	13-16	putative glycine--tRNA ligase	Saccharomyces cerevisiae S288C	43-47
28916765-1	2017	The alanine:glyoxylate aminotransferase (AGT), a hepatocyte-specific pyridoxal-5"-phosphate (PLP) dependent enzyme, transaminates L-alanine and glyoxylate to glycine and pyruvate, thus detoxifying glyoxylate and preventing pathological oxalate precipitation in tissues.	Glycine	158-165	pyridoxal phosphatase	Homo sapiens	93-96
22056771-6	2011	Notably, the catalytic cysteine residue in Atg7 is positioned close to the C-terminal glycine of Atg8, its target for thioester formation, potentially eliminating the need for large conformational rearrangements characteristic of other E1s.	Glycine	86-93	autophagy related 7	Homo sapiens	43-47
21880725-2	2011	Here we cloned, expressed, and characterized a novel LOX isoform from the model vertebrate Danio rerio (zebrafish) that carries a Gly at this critical position, classifying this enzyme as putative arachidonic acid R-LOX.	Glycine	130-133	lysyl oxidase a	Danio rerio	53-56
22325350-3	2012	Biochemical and NMR data indicate that hnRNP A1 forms a ternary complex with the U2AF heterodimer on AG-containing/uridine-rich RNAs, while it displaces U2AF from non-AG-containing/uridine-rich RNAs, an activity that requires the glycine-rich domain of hnRNP A1.	Glycine	230-237	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	39-47
28514141-3	2017	In particular, compounds 15a and 16a are potent GluN2C-specific superagonists at the GluN1 subunit with agonist efficacies of 398% and 308% compared to glycine.	Glycine	152-159	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	48-54
22225612-4	2012	Overexpression of GLDC and other glycine/serine enzymes, but not catalytically inactive GLDC, promotes cellular transformation and tumorigenesis.	Glycine	33-40	glycine decarboxylase	Homo sapiens	18-22
22225612-5	2012	We found that GLDC induces dramatic changes in glycolysis and glycine/serine metabolism, leading to changes in pyrimidine metabolism to regulate cancer cell proliferation.	Glycine	62-69	glycine decarboxylase	Homo sapiens	14-18
28514141-4	2017	This study demonstrates that subunit-selectivity among glycine site NMDA receptor agonists can be achieved and suggests that glycine-site agonists can be developed as pharmacological tool compounds to study GluN2C-specific effects in NMDA receptor-mediated neurotransmission.	Glycine	125-132	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	207-213
22044943-11	2012	This study provides first evidence that (1) high-glycine can induce plasticity at glutamatergic synapses in CGCs, and (2) that acute NRG1/ErbB-signaling can regulate glutamatergic plasticity in CGCs.	Glycine	49-56	neuregulin 1	Homo sapiens	133-137
21984184-3	2011	Here we demonstrate that in human and Drosophila melanogaster cells, the critical repressive features of both the N-terminal and C-terminal effector domains of GW182 proteins are Gly/Ser/Thr-Trp (G/S/TW) or Trp-Gly/Ser/Thr (WG/S/T) motifs.	Glycine	179-182	gawky	Drosophila melanogaster	160-165
28749574-8	2017	However, the analogous phenols 16 c ((3-phenylpropyl)amino moiety) and 16 d ((4-phenylbutyl)amino moiety) with 10-fold lower GluN2B affinity (Ki =28 and 21 nm, respectively) showed promising inhibition of glutamate-/glycine-evoked effects in both assays.	Glycine	216-223	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	125-131
21984184-3	2011	Here we demonstrate that in human and Drosophila melanogaster cells, the critical repressive features of both the N-terminal and C-terminal effector domains of GW182 proteins are Gly/Ser/Thr-Trp (G/S/TW) or Trp-Gly/Ser/Thr (WG/S/T) motifs.	Glycine	211-214	gawky	Drosophila melanogaster	160-165
21640146-2	2011	The tumor vasculature-specific ligand asparagine-glycine-arginine (NGR) peptide targets the isoform of aminopeptidase N (APN, also referred to as CD13) that is expressed on the endothelial cells in angiogenic vessels such as the neovasculature in tumors.	Glycine	49-56	alanyl aminopeptidase, membrane	Homo sapiens	103-119
28824188-5	2017	A novel mutation (173 A&gt;G) in exon 4 with a predicted amino acid change of 58 Asp&gt;Gly was also found in a Kinh newborn girl and her father, and it was designated as G6PD Ho Chi Minh.	Glycine	88-91	kinesin family member 5B	Homo sapiens	112-116
21640146-2	2011	The tumor vasculature-specific ligand asparagine-glycine-arginine (NGR) peptide targets the isoform of aminopeptidase N (APN, also referred to as CD13) that is expressed on the endothelial cells in angiogenic vessels such as the neovasculature in tumors.	Glycine	49-56	alanyl aminopeptidase, membrane	Homo sapiens	121-124
21640146-2	2011	The tumor vasculature-specific ligand asparagine-glycine-arginine (NGR) peptide targets the isoform of aminopeptidase N (APN, also referred to as CD13) that is expressed on the endothelial cells in angiogenic vessels such as the neovasculature in tumors.	Glycine	49-56	alanyl aminopeptidase, membrane	Homo sapiens	146-150
21653555-5	2011	Moreover, we demonstrate that AT1G36310, denoted AtALKBH8, is required for hydroxylation of mcm(5)U to (S)-mchm(5)U in tRNA(Gly)(UCC), and has a function similar to the mammalian dioxygenase ALKBH8.	Glycine	124-127	alkB homolog 8, tRNA methyltransferase	Homo sapiens	51-57
28325525-0	2017	Clinical heterogeneity of glycine encephalopathy in three Palestinian siblings: A novel mutation in the glycine decarboxylase (GLDC) gene.	Glycine	26-33	glycine decarboxylase	Homo sapiens	104-125
28325525-0	2017	Clinical heterogeneity of glycine encephalopathy in three Palestinian siblings: A novel mutation in the glycine decarboxylase (GLDC) gene.	Glycine	26-33	glycine decarboxylase	Homo sapiens	127-131
28627136-4	2017	ERH interacts directly in the nucleus with the C-terminal Arg-Gly-rich region of SAFB1/2 and co-localizes with it in the insoluble nuclear fraction.	Glycine	62-65	ERH mRNA splicing and mitosis factor	Homo sapiens	0-3
21757738-8	2011	Thus we investigated its role in a Huntington disease cellular model and found that FAT10 molecules were covalently attached to huntingtin through their C terminus glycine.	Glycine	164-171	huntingtin	Homo sapiens	128-138
28524260-11	2017	Interestingly, the glycine-evoked currents in dissociated DRD1-positive MSNs were potentiated by ethanol.	Glycine	19-26	dopamine receptor D1	Mus musculus	58-62
21762704-5	2011	Gly injection also induced protein carbonyl formation, as well as elevation of the activities of glutathione peroxidase, glutathione reductase, catalase and superoxide dismutase.	Glycine	0-3	glutathione-disulfide reductase	Homo sapiens	121-142
28740143-4	2017	The gene SLC25A38, responsible for transporting glycine from cytoplasm to mitochondria, and the gene ALAS1, encoding rate-limiting enzyme (delta-aminolevulinic acid synthase 1), had higher expression at 15 hr, as compared with 2, 5 and 23.5 hrs postoviposition.	Glycine	48-55	solute carrier family 25 member 38	Gallus gallus	9-17
21743476-8	2011	A structural comparison of the CENP-A and H3 nucleosomes revealed that CENP-A contains two extra amino acid residues (Arg 80 and Gly 81) in the loop 1 region, which is completely exposed to the solvent.	Glycine	129-132	centromere protein A	Homo sapiens	71-77
28583108-4	2017	RESULTS: Target region capture sequencing yielded a novel missense mutation in codon 2304 (G2304R), which is a heterozygous A to G point mutation at position 6910 (c.6910A &gt; G) in exon 46 of SYNE1 leading to a glycine-to-arginine substitution (p.Gly2304Arg).	Glycine	213-220	spectrin repeat containing nuclear envelope protein 1	Homo sapiens	194-199
21677647-3	2011	These receptors form heteromeric ion channels and become activated after concurrent binding of glycine and glutamate to the GluN1 and GluN2 subunits, respectively.	Glycine	95-102	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	124-129
21487005-6	2011	Conversion of serine to glycine at an ERK1/2 phosphorylation site (S281G) abolished the cAMP activation of TRPC6 as determined by whole-cell and cell-attached single-channel patch recordings.	Glycine	24-31	transient receptor potential cation channel subfamily C member 6	Homo sapiens	107-112
28698298-1	2017	The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5" cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine-tyrosine-phenylalanine domain) proteins 1 and 2 (GIGYF1/2).	Glycine	254-261	eukaryotic translation initiation factor 4E	Homo sapiens	4-9
21404362-4	2011	As well, an homology model of the three-dimensional structure of human hemopexin is used to reveal that the protein lacks the catalytic triad that is characteristic of many serine proteases but that hemopexin possesses two highly exposed Arg-Gly-Glu sequences that may promote interaction with cell surfaces.	Glycine	242-245	hemopexin	Homo sapiens	71-80
28698298-1	2017	The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5" cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine-tyrosine-phenylalanine domain) proteins 1 and 2 (GIGYF1/2).	Glycine	254-261	eukaryotic translation initiation factor 4E	Homo sapiens	88-93
21404362-4	2011	As well, an homology model of the three-dimensional structure of human hemopexin is used to reveal that the protein lacks the catalytic triad that is characteristic of many serine proteases but that hemopexin possesses two highly exposed Arg-Gly-Glu sequences that may promote interaction with cell surfaces.	Glycine	242-245	hemopexin	Homo sapiens	199-208
28698298-1	2017	The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5" cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine-tyrosine-phenylalanine domain) proteins 1 and 2 (GIGYF1/2).	Glycine	254-261	GRB10 interacting GYF protein 1	Homo sapiens	311-317
28452351-0	2017	Motor neuron disease: Detection of glycine-proline repeat protein offers new biomarker in patients with C9orf72 expansion.	Glycine	35-42	C9orf72-SMCR8 complex subunit	Homo sapiens	104-111
21306143-0	2011	VX680 binding in Aurora A: pi-pi interactions involving the conserved aromatic amino acid of the flexible glycine-rich loop.	Glycine	106-113	aurora kinase A	Homo sapiens	17-25
28603500-5	2017	Conclusions:EPCR gene Ser219Gly polymorphism was associated with an elevated risk of VTE and the Gly residue carriers of the EPCR gene might be predisposed to VTE.	Glycine	28-31	protein C receptor	Homo sapiens	12-16
21266584-2	2011	They share high similarity in their catalytic domains but differ in their N- and C-terminal regions, with GSK-3alpha having an extended glycine-rich N terminus.	Glycine	136-143	glycogen synthase kinase 3 alpha	Homo sapiens	106-116
28515681-6	2017	Further analysis revealed that Meg3 loss of function blocked the glycine-induced increase of the GluA1 subunit of AMPA receptors on the plasma membrane, a major hallmark of LTP.	Glycine	65-72	glutamate receptor, ionotropic, AMPA1 (alpha 1)	Mus musculus	97-102
21316454-3	2011	Our findings demonstrate neuroprotection in neuronal cultures treated with the small molecule (KN-93) and peptide (tat-AIP and tat-CN21) inhibitors of CaMKII immediately prior to excitotoxic glutamate/glycine insult.	Glycine	201-208	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	151-157
28298598-7	2017	Interestingly, cleavage of pVIII at both potential cleavage sites appears essential for the production of stable BAdV-3 virions as BAdV-3 expressing pVIII containing a glycine-to-alanine mutation of either of the potential cleavage sites is thermolabile, and this mutation leads to the production of noninfectious virions.IMPORTANCE Here, we demonstrated that the BAdV-3 adenovirus protease cleaves BAdV-3 pVIII at both potential protease cleavage sites.	Glycine	168-175	pVIII	Bovine adenovirus 3	27-32
21308994-9	2011	A similar effect on E(GABA/Gly) was induced by the NKCC1 inhibitor bumetanide.	Glycine	27-30	solute carrier family 12 member 2	Rattus norvegicus	51-56
21308994-12	2011	We propose that CFTR operated together with NKCC1 to produce depolarizing GABA/glycine mediated synaptic events.	Glycine	79-86	solute carrier family 12 member 2	Rattus norvegicus	44-49
28298598-9	2017	Further analysis indicated that the mutation of a single protease cleavage site (glycine to alanine) of pVIII produces thermolabile virions, which leads to the production of noninfectious virions with disrupted capsids.	Glycine	81-88	pVIII	Bovine adenovirus 3	104-109
28401144-5	2017	In contrast, an earlier in vivo mutational study identified a glycine to arginine mutation at the position 168 on the B. subtilis SPL that is &gt;15 A away from the enzyme active site.	Glycine	62-69	sphingosine-1-phosphate lyase 1	Homo sapiens	130-133
28401144-11	2017	All these data imply that the mutation at the remote glycine 168 residue alters the enzyme 3D structure, subsequently reducing the SPL activity by changing the positions of the essential amino acids involved in the radical transfer process.	Glycine	53-60	sphingosine-1-phosphate lyase 1	Homo sapiens	131-134
21281805-6	2011	Neutrophils can migrate in response to chemotactic gradients established through the action of gelatinases (eg, matrix metalloproteinase 9), which degrade collagen components of the extracellular matrix to generate tripeptide fragments of proline-glycine-proline.	Glycine	247-254	matrix metallopeptidase 9	Mus musculus	112-138
28005359-5	2017	Crystal structures of inhibitor-kinase complexes showed that the inhibitor stabilizes a glycine-rich loop conformation that shapes the ATP ribose binding pocket and that is preferred in CDK2 but has not been observed in CDK1.	Glycine	88-95	cyclin dependent kinase 2	Homo sapiens	186-190
28077638-0	2017	A Conserved Glycine Residue Is Required for Proper Functioning of a Baculovirus VP39 Protein.	Glycine	12-19	VP39	Bombyx mori nucleopolyhedrovirus	80-84
21264427-0	2011	Characterization of the recombinant copper chaperone (CCS) from the plant Glycine (G.) max.	Glycine	74-81	copper chaperone for superoxide dismutase	Homo sapiens	54-57
28077638-11	2017	Combined with the results of transmission electron microscopy, VP39 Gly-276 can be concluded to be essential for correct nucleocapsid assembly, viral DNA packaging, and viral gene expression, especially of very late genes.IMPORTANCE The major nucleocapsid protein gene vp39 is one of the most well-known baculovirus genes.	Glycine	68-71	VP39	Bombyx mori nucleopolyhedrovirus	63-67
28077638-11	2017	Combined with the results of transmission electron microscopy, VP39 Gly-276 can be concluded to be essential for correct nucleocapsid assembly, viral DNA packaging, and viral gene expression, especially of very late genes.IMPORTANCE The major nucleocapsid protein gene vp39 is one of the most well-known baculovirus genes.	Glycine	68-71	VP39	Bombyx mori nucleopolyhedrovirus	269-273
22030899-5	2012	An analysis of the cleavage site specificities of the three proteases in tropoelastin and elastin revealed that HLE and PR3 similarly tolerate hydrophobic and/or aliphatic amino acids such as Ala, Gly and Val at P(1), which are also preferred by CG.	Glycine	197-200	proteinase 3	Homo sapiens	120-123
28077638-13	2017	The present study revealed that the glycine residue at residue 276, which is completely conserved among sequenced alphabaculoviruses, betabaculoviruses, and gammabaculoviruses, is important for the VP39 function, i.e., structural assembly of nucleocapsids and viral DNA packaging.	Glycine	36-43	VP39	Bombyx mori nucleopolyhedrovirus	198-202
27841152-6	2017	Accumulation through systemic exposure of both IND and GLY from day 1 to day 14 was observed (mean accumulation ratio (R&lt;sub&gt;acc&lt;/sub&gt;) of AUC&lt;sub&gt;0-24h&lt;/sub&gt; (day 14/day 1): IND, 3.02; GLY 2.94; estimated accumulation ratio of C&lt;sub&gt;max&lt;/sub&gt;: IND 1.56; GLY 1.33).	Glycine	55-58	threonine aldolase 1, pseudogene	Homo sapiens	291-296
23481570-7	2012	The allele types of FGFR4 amino acid 388 in 24 OSCC patients were Arg/Arg (8.3%), Arg/Gly (54.2%) and Gly/Gly (37.5%).	Glycine	86-89	fibroblast growth factor receptor 4	Homo sapiens	20-25
23481570-7	2012	The allele types of FGFR4 amino acid 388 in 24 OSCC patients were Arg/Arg (8.3%), Arg/Gly (54.2%) and Gly/Gly (37.5%).	Glycine	102-105	fibroblast growth factor receptor 4	Homo sapiens	20-25
23481570-7	2012	The allele types of FGFR4 amino acid 388 in 24 OSCC patients were Arg/Arg (8.3%), Arg/Gly (54.2%) and Gly/Gly (37.5%).	Glycine	102-105	fibroblast growth factor receptor 4	Homo sapiens	20-25
21285950-5	2011	Through in vitro and in vivo studies, we show that both diastereomers of mchm(5)U are generated from mcm(5)U, and that the AlkB domain of ALKBH8 specifically hydroxylates mcm(5)U into (S)-mchm(5)U in tRNA-Gly(UCC).	Glycine	205-208	alkB homolog 8, tRNA methyltransferase	Homo sapiens	138-144
21591931-2	2011	The secreted proLOX is enzymatically quiescent and is activated through proteolytic cleavage between residues Gly(162) and Asp(163) (residue numbers according to the mouse LOX) by bone morphogenetic protein (BMP)-1 gene products.	Glycine	110-113	lysyl oxidase	Mus musculus	16-19
23481570-9	2012	The patients carrying FGFR4 allele Arg/Arg or Arg/Gly at amino acid 388 were associated with advanced N stage (pathologic N2+N3), compared to Gly/Gly allele carrying group (p=0.009).	Glycine	50-53	fibroblast growth factor receptor 4	Homo sapiens	22-27
28150868-0	2017	Identification of second arginine-glycine-aspartic acid motif of ovine vitronectin as the complement C9 binding site and its implication in bacterial infection.	Glycine	34-41	vitronectin	Capra hircus	71-82
23481570-9	2012	The patients carrying FGFR4 allele Arg/Arg or Arg/Gly at amino acid 388 were associated with advanced N stage (pathologic N2+N3), compared to Gly/Gly allele carrying group (p=0.009).	Glycine	142-145	fibroblast growth factor receptor 4	Homo sapiens	22-27
23481570-9	2012	The patients carrying FGFR4 allele Arg/Arg or Arg/Gly at amino acid 388 were associated with advanced N stage (pathologic N2+N3), compared to Gly/Gly allele carrying group (p=0.009).	Glycine	142-145	fibroblast growth factor receptor 4	Homo sapiens	22-27
23481570-11	2012	In this study, FGFR4 Arg allele carrier was associated with higher N stage compared with Gly allele.	Glycine	89-92	fibroblast growth factor receptor 4	Homo sapiens	15-20
21591931-2	2011	The secreted proLOX is enzymatically quiescent and is activated through proteolytic cleavage between residues Gly(162) and Asp(163) (residue numbers according to the mouse LOX) by bone morphogenetic protein (BMP)-1 gene products.	Glycine	110-113	bone morphogenetic protein 1	Mus musculus	180-214
21304263-2	2011	This biological activity of OPN may be attributed to its characteristic structure, which includes 2 calcium binding sites, Arg-Gly-Asp (RGD) sequences.	Glycine	127-130	secreted phosphoprotein 1	Mus musculus	28-31
22175728-2	2012	In the proteolytic processing of mouse DSPP, the peptide bond at Gly(451)-Asp(452) has been shown to be cleaved by bone morphogenetic protein 1 (BMP1)/Tolloid-like metalloproteinases.	Glycine	65-68	bone morphogenetic protein 1	Mus musculus	115-143
28787736-8	2017	Bet v 1-, Cor a 1.0101-, and Aln g 1-specific IgE recognition was associated with respiratory symptoms, whilst Ara h 8, Cor a 1.0401, Gly m 4, Mal d 1, and Pru p 1 were selectively linked to an oral allergic syndrome.	Glycine	134-137	delta/notch like EGF repeat containing	Homo sapiens	0-3
22175728-2	2012	In the proteolytic processing of mouse DSPP, the peptide bond at Gly(451)-Asp(452) has been shown to be cleaved by bone morphogenetic protein 1 (BMP1)/Tolloid-like metalloproteinases.	Glycine	65-68	bone morphogenetic protein 1	Mus musculus	145-149
20821241-3	2011	The molecular structure of (R)-DW12 with the CO ligand oriented perpendicular to the pyridocarbazole heterocycle allows the complex to stretch the whole distance sandwiched between the faces of the N- and C-terminal lobes and to interact tightly with the flexible glycine-rich loop, which is uncommon for the interaction of GSK-3beta with organic inhibitors.	Glycine	264-271	glycogen synthase kinase 3 beta	Homo sapiens	324-333
32714574-3	2017	The phenotype of a glycinergic neuron is determined by the expression of at least two proteins: GlyT2, a plasma membrane transporter of glycine, and VIAAT, a vesicular transporter shared by glycine and GABA.	Glycine	19-26	solute carrier family 6 member 5	Homo sapiens	96-101
22194882-7	2011	In this work, several glycine- and hydroxyglycine-extended peptides as well as amidated peptides were qualitatively and quantitatively assessed from pituitaries of wild-type mice and mice with a single copy of the Pam gene (PAM(+/-)) via liquid chromatography-mass spectrometry-based methods.	Glycine	22-29	peptidylglycine alpha-amidating monooxygenase	Mus musculus	214-217
20958962-10	2010	Conversely, "conventional" receptors assembled from NR1 and NR2 could be made Mg2+ insensitive and Ca2+ impermeable by equipping either subunit with the NR3-like glycine at their N positions, with a stronger contribution of the NR1 subunit.	Glycine	162-169	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	153-156
20818167-5	2010	With the LC3B-PLA(2) substrate, we show that mutation of the glycine proximal to the scissile bond in LC3B abolishes activity.	Glycine	61-68	microtubule associated protein 1 light chain 3 beta	Homo sapiens	9-13
32714574-3	2017	The phenotype of a glycinergic neuron is determined by the expression of at least two proteins: GlyT2, a plasma membrane transporter of glycine, and VIAAT, a vesicular transporter shared by glycine and GABA.	Glycine	136-143	solute carrier family 6 member 5	Homo sapiens	96-101
27798331-8	2016	Glycine treatment led to increased DNA replication (by 70-80%) while enhancing mTORC1 activation by upregulating Akt and inhibiting AMPK signaling (P &lt; 0.05).	Glycine	0-7	CREB regulated transcription coactivator 1	Mus musculus	79-85
27798331-14	2016	Glycine regulates protein turnover by activating mTORC1 and by inhibiting the expression of genes for proteolysis.	Glycine	0-7	CREB regulated transcription coactivator 1	Mus musculus	49-55
27891122-3	2016	Recently, the C-terminal glycine-rich fragments of human epithelial keratin 6A were found to have bactericidal and cytoprotective activities.	Glycine	25-32	keratin 6A	Homo sapiens	68-78
20818167-5	2010	With the LC3B-PLA(2) substrate, we show that mutation of the glycine proximal to the scissile bond in LC3B abolishes activity.	Glycine	61-68	microtubule associated protein 1 light chain 3 beta	Homo sapiens	102-106
25721693-9	2016	GLY reduced the levels of proteins, including nuclear NF-kappaB (p65 and p50), p-IKK (ser176), p-IkappaB, p-AKT, p-ERK, and nuclear Egr-1 in a time and dose-dependent manner.	Glycine	0-3	RELA proto-oncogene, NF-kB subunit	Homo sapiens	65-68
20549332-2	2010	Through PCR-RFLP and DNA sequencing methods, a new allelic variant corresponding to the A --&gt; G mutation (aspartic to glycine amino acid replacement) of the bovine CACNA2D1 gene was detected.	Glycine	121-139	calcium voltage-gated channel auxiliary subunit alpha2delta 1	Bos taurus	167-175
27669208-5	2016	Their activity as catalysts was assessed and Sm-FAp/Glycine displayed excellent efficiency in the synthesis of 1,2,4-triazole catalyzing the reaction between 2-nitrobenzaldehyde and thiosemicarbazide with exceptional selectivity and 98% yield in a short time interval (10 min).	Glycine	52-59	fibroblast activation protein alpha	Homo sapiens	48-51
20643479-2	2010	Here, we focused on integrin-mediated cell-scaffold adhesion and prepared cell adhesive fibroin in which a tandem repeat of the Arg-Gly-Asp-Ser (RGDS) sequence was genetically interfused in the fibroin light chain (L-chain) (L-RGDSx2 fibroin).	Glycine	132-135	ral guanine nucleotide dissociation stimulator	Homo sapiens	145-149
20558222-11	2010	In conclusion, GlyT1 and CAT1 most likely mediate glycine and L-arginine uptake, respectively, by Muller cells and are expected to play an important role in supplying precursors for creatine biosynthesis in Muller cells.	Glycine	50-57	solute carrier family 7 member 1	Rattus norvegicus	25-29
27464742-1	2016	This study is focused on a new amide derivative of the peptide HLDF-6 (Thr-Gly-Glu-Asn-His-Arg).	Glycine	75-78	ribosomal protein S21	Homo sapiens	63-67
20728365-0	2010	Replacement of the Lys linker with an Arg linker resulting in improved melanoma uptake and reduced renal uptake of Tc-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptide.	Glycine	134-137	pro-opiomelanocortin-alpha	Mus musculus	153-189
20558765-6	2010	We found that uptake of glycine-sarcosine, a specific substrate of PepT1, in intestinal epithelial Caco2-BBE cells was inhibited by Tri-DAP in a dose-dependent manner.	Glycine	24-31	death associated protein	Homo sapiens	136-139
27358403-7	2016	The polymorphic nature of position 241 in both CELA3A (~4% Ala(241) alleles) and CELA3B (~2% Gly(241) alleles) points to individual variations in complex formation.	Glycine	93-96	chymotrypsin like elastase 3A	Homo sapiens	47-53
27083399-1	2016	The Col1a2(+/G610C) knock-in mouse, models osteogenesis imperfecta in a large old order Amish family (OOA) with type IV OI, caused by a G-to-T transversion at nucleotide 2098, which alters the gly-610 codon in the triple-helical domain of the alpha2(I) chain of type I collagen.	Glycine	193-196	collagen, type I, alpha 2	Mus musculus	4-10
20435891-2	2010	GrB is synthesized as a zymogen (proGrB) and activated in cytotoxic granules by the lysosomal cysteine protease cathepsin C (CatC) which removes the N-terminal dipeptide Gly-Glu.	Glycine	170-173	granzyme B	Mus musculus	0-3
20435891-2	2010	GrB is synthesized as a zymogen (proGrB) and activated in cytotoxic granules by the lysosomal cysteine protease cathepsin C (CatC) which removes the N-terminal dipeptide Gly-Glu.	Glycine	170-173	cathepsin C	Mus musculus	112-123
20435891-2	2010	GrB is synthesized as a zymogen (proGrB) and activated in cytotoxic granules by the lysosomal cysteine protease cathepsin C (CatC) which removes the N-terminal dipeptide Gly-Glu.	Glycine	170-173	cathepsin C	Mus musculus	125-129
27058626-7	2016	Furthermore, the Gly administration caused significant reduction in the ethanol-induced neuroinflammation by inhibiting the expression of inflammatory markers such as p-NF-kB, cyclooxygenase 2 (COX2) and tumor necrosis factor-alpha (TNF-alpha) and reversed the ethanol-induced synaptic protein markers expression.	Glycine	17-20	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	176-192
27058626-7	2016	Furthermore, the Gly administration caused significant reduction in the ethanol-induced neuroinflammation by inhibiting the expression of inflammatory markers such as p-NF-kB, cyclooxygenase 2 (COX2) and tumor necrosis factor-alpha (TNF-alpha) and reversed the ethanol-induced synaptic protein markers expression.	Glycine	17-20	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	194-198
27148589-0	2016	Mutations in the substrate binding glycine-rich loop of the mitochondrial processing peptidase-alpha protein (PMPCA) cause a severe mitochondrial disease.	Glycine	35-42	peptidase, mitochondrial processing subunit alpha	Homo sapiens	110-115
21326622-8	2010	In addition, when HgCl(2) was coapplied with glycine, responses were changed in the A288C/Y406C, A288C/I409C, and A288C/Y410C double mutants, suggesting that agonist-induced rotation of TM4 allows A288C/Y406C and A288C/I409C to cross-link.	Glycine	45-52	tropomyosin 4 S homeolog	Xenopus laevis	186-189
27148589-4	2016	The variants were located close to and postulated to affect the substrate binding glycine-rich loop of the alpha-MPP protein.	Glycine	82-89	peptidase, mitochondrial processing subunit alpha	Homo sapiens	107-116
26650776-10	2016	CONCLUSIONS: QM/MM calculations coupled to fingerprinting analyses revealed that two Arg of AtGAPA (substituted by Gly and Val in AtGAPC1), located at 8-15 A distance from Cys149, are the major factors responsible for sulfenic acid stability, underpinning the importance of long-distance polar interactions in tuning sulfenic acid stability in native protein microenvironments.	Glycine	115-118	glyceraldehyde 3-phosphate dehydrogenase A subunit	Arabidopsis thaliana	92-98
20430876-8	2010	Gly-Sar-induced pH(i) decrease was no longer observed in the absence of PEPT1.	Glycine	0-3	glucose-6-phosphate isomerase 1	Mus musculus	16-21
20382160-9	2010	Exchange of glycine for methionine increased the catalytic activity of 17beta-HSD1 toward all-trans retinal in zebrafish but not in the human enzyme, in which the opposite effect was observed.	Glycine	12-19	RNA, U1 small nuclear 1	Homo sapiens	71-82
26680103-6	2016	Further analysis revealed that a 6-bp deletion mutation resulted in deletion of Met and Gly residues at positions 495 and 496 in TYRP1 protein, and altered the structure of transmembrane domain of TYRP1.	Glycine	88-91	tyrosinase related protein 1	Sus scrofa	129-134
20213214-2	2010	Here we have developed a novel strategy to pattern cells using a hyaluronic acid hydrogel material and photocaged RGDS (Arg-Gly-Asp-Ser) peptides.	Glycine	124-127	ral guanine nucleotide dissociation stimulator	Homo sapiens	114-118
26680103-6	2016	Further analysis revealed that a 6-bp deletion mutation resulted in deletion of Met and Gly residues at positions 495 and 496 in TYRP1 protein, and altered the structure of transmembrane domain of TYRP1.	Glycine	88-91	tyrosinase related protein 1	Sus scrofa	197-202
26912818-5	2016	Glycine and proline only marginally stimulated the IL-8 production by IL-1beta-stimulated gingival fibroblast, whereas glycine dose-dependently inhibited the nitric oxide production by lipopolysaccharide-stimulated mouse macrophage-like RAW264.7 cells.	Glycine	0-7	chemokine (C-X-C motif) ligand 15	Mus musculus	51-55
26879662-5	2016	At position 389 of the beta-1 adrenergic receptor gene (ADRB1), the observed minor Gly allele frequency (Gly389Arg + Gly389Gly) was 0.21, and no deviation from Hardy-Weinberg equilibrium was observed in the genotypic distribution of Arg389Gly (p = 0.75).	Glycine	83-86	adrenoceptor beta 1	Homo sapiens	23-49
20181793-6	2010	Regions in these loops that play crucial roles in CST"s activity were identified by Gly substitutions.	Glycine	84-87	solute carrier family 35 member A1	Homo sapiens	50-53
26879662-5	2016	At position 389 of the beta-1 adrenergic receptor gene (ADRB1), the observed minor Gly allele frequency (Gly389Arg + Gly389Gly) was 0.21, and no deviation from Hardy-Weinberg equilibrium was observed in the genotypic distribution of Arg389Gly (p = 0.75).	Glycine	83-86	adrenoceptor beta 1	Homo sapiens	56-61
22119847-7	2012	Here we analyzed the interactions between CLIP-170 and p150(glued) CAP-Gly domains with the three EB homodimers and the EB1-EB3 heterodimer.	Glycine	71-74	chromatin assembly factor 1 subunit A	Homo sapiens	55-66
26547262-9	2016	CONCLUSIONS &amp; INFERENCES: The results demonstrate that in cisplatin long-term treated mice [Gly(2) ]GLP-2 is able to counteract both the mucosal gastric fundus damage, by preventing the epithelium thickness decrease, and the neuropathy, by protecting the nNOS neurons.	Glycine	96-99	glucagon-like peptide 2 receptor	Mus musculus	104-109
22119847-10	2012	We succeeded to solve the crystal structure of a complex composed of a heterodimer of EB1 and EB3 C-termini together with the CAP-Gly domain of p150(glued).	Glycine	130-133	chromatin assembly factor 1 subunit A	Homo sapiens	144-148
26547262-9	2016	CONCLUSIONS &amp; INFERENCES: The results demonstrate that in cisplatin long-term treated mice [Gly(2) ]GLP-2 is able to counteract both the mucosal gastric fundus damage, by preventing the epithelium thickness decrease, and the neuropathy, by protecting the nNOS neurons.	Glycine	96-99	nitric oxide synthase 1, neuronal	Mus musculus	259-263
22119847-10	2012	We succeeded to solve the crystal structure of a complex composed of a heterodimer of EB1 and EB3 C-termini together with the CAP-Gly domain of p150(glued).	Glycine	130-133	chromatin assembly factor 1 subunit A	Homo sapiens	149-154
20154084-1	2010	Atg18 and Atg21 are homologous WD-40 repeat proteins that bind phosphoinositides via a novel conserved Phe-Arg-Arg-Gly motif and function in autophagy-related pathways.	Glycine	115-118	WD repeat domain, phosphoinositide interacting 2	Homo sapiens	10-15
22693611-6	2012	In vitro studies revealed that COUP-TFII interacts with the C-terminal arginine-glycine repeat (RGG) domain of nucleolin.	Glycine	80-87	nucleolin	Homo sapiens	111-120
26547262-10	2016	Taken together, the present data suggest that [Gly(2) ]GLP-2 could represent an effective strategy to overcome the distressing gastrointestinal symptoms present during the anti-neoplastic therapy.	Glycine	47-50	glucagon-like peptide 2 receptor	Mus musculus	55-60
22693631-2	2012	As other ubiquitin-like proteins (Ubls), ISG15 is post-translationally conjugated to substrate proteins by an isopeptide bond between the C-terminal glycine of ISG15 and the side chains of lysine residues in the substrates (ISGylation).	Glycine	149-156	ISG15 ubiquitin like modifier	Homo sapiens	41-46
22693631-2	2012	As other ubiquitin-like proteins (Ubls), ISG15 is post-translationally conjugated to substrate proteins by an isopeptide bond between the C-terminal glycine of ISG15 and the side chains of lysine residues in the substrates (ISGylation).	Glycine	149-156	ISG15 ubiquitin like modifier	Homo sapiens	160-165
26659906-1	2016	We describe the 3D supramolecular structure of Fmoc-RGDS fibrils, where Fmoc and RGDS refer to the hydrophobic N-(fluorenyl-9-methoxycarbonyl) group and the hydrophilic Arg-Gly-Asp-Ser peptide sequence, respectively.	Glycine	173-176	ral guanine nucleotide dissociation stimulator	Homo sapiens	52-56
22106265-5	2011	The IAPP(8-37) analogs share common structure motifs of IAPP(8-17) and IAPP(26-37) with the most probable key sites at positions around Ser(19)/Ser(20) and Gly(24).	Glycine	156-159	islet amyloid polypeptide	Homo sapiens	4-8
20033765-5	2010	Eleven glycine residues were conserved for all of the opossum ALDH3-like sequences examined, including two glycine residues previously located within the stem of the rat ALDH3A1 active site funnel.	Glycine	7-14	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	62-67
20033765-5	2010	Eleven glycine residues were conserved for all of the opossum ALDH3-like sequences examined, including two glycine residues previously located within the stem of the rat ALDH3A1 active site funnel.	Glycine	107-114	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	62-67
20033765-5	2010	Eleven glycine residues were conserved for all of the opossum ALDH3-like sequences examined, including two glycine residues previously located within the stem of the rat ALDH3A1 active site funnel.	Glycine	107-114	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	170-177
20799661-3	2010	Also it was shown that enkephalins, VIP and SS are potent to augment the inhibiting effect of GABA and glycine.	Glycine	103-110	somatostatin	Felis catus	44-46
26659906-1	2016	We describe the 3D supramolecular structure of Fmoc-RGDS fibrils, where Fmoc and RGDS refer to the hydrophobic N-(fluorenyl-9-methoxycarbonyl) group and the hydrophilic Arg-Gly-Asp-Ser peptide sequence, respectively.	Glycine	173-176	ral guanine nucleotide dissociation stimulator	Homo sapiens	81-85
26722042-1	2016	BACKGROUND: The metabolic enzyme, glycine dehydrogenase (GLDC), involved in glycine metabolism, is known to be involved in non-ketotic hyperglycinemia but not in cancer.	Glycine	34-41	glycine decarboxylase	Homo sapiens	57-61
20133584-7	2010	Analysis of Trx h9 revealed a 17-amino acid N-terminal extension in which the second Gly (Gly(2)) and fourth cysteine (Cys(4)) were highly conserved.	Glycine	85-88	thioredoxin H-type 9	Arabidopsis thaliana	12-18
20164358-2	2010	DCS shows partial agonism at NR1/NR2B but has higher relative efficacy than glycine at NR1/NR2C receptor.	Glycine	76-83	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	91-95
20021564-5	2010	Here we identify the N-terminal glycine of the GxGD motif in PS1, G382, as a critical residue of the active site domain of gamma-secretase.	Glycine	32-39	presenilin 1	Homo sapiens	61-64
19903819-5	2010	Expression cloning and sequencing of the cDNA obtained from GroD1 revealed a point mutation, Gly-189 --&gt; Glu, in glucose-6-phosphate isomerase (GPI), a glycolytic enzyme involved in an inherited disorder that results in anemia and neuromuscular symptoms in humans.	Glycine	93-96	glucose-6-phosphate isomerase	Homo sapiens	116-145
19903819-5	2010	Expression cloning and sequencing of the cDNA obtained from GroD1 revealed a point mutation, Gly-189 --&gt; Glu, in glucose-6-phosphate isomerase (GPI), a glycolytic enzyme involved in an inherited disorder that results in anemia and neuromuscular symptoms in humans.	Glycine	93-96	glucose-6-phosphate isomerase	Homo sapiens	147-150
19818814-3	2010	By using the fusion expression with unique acid labile linker Asp-Pro and biochemical purification, the three novel GHRH peptides, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys, Pro-hGHRH(1-44)-Gly-Gly-Cys, and (1)Pro-GHRH(2-44)-Gly-Gly-Cys, were obtained.	Glycine	151-154	growth hormone releasing hormone	Rattus norvegicus	116-120
19818814-3	2010	By using the fusion expression with unique acid labile linker Asp-Pro and biochemical purification, the three novel GHRH peptides, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys, Pro-hGHRH(1-44)-Gly-Gly-Cys, and (1)Pro-GHRH(2-44)-Gly-Gly-Cys, were obtained.	Glycine	151-154	growth hormone releasing hormone	Rattus norvegicus	140-144
19818814-3	2010	By using the fusion expression with unique acid labile linker Asp-Pro and biochemical purification, the three novel GHRH peptides, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys, Pro-hGHRH(1-44)-Gly-Gly-Cys, and (1)Pro-GHRH(2-44)-Gly-Gly-Cys, were obtained.	Glycine	155-158	growth hormone releasing hormone	Rattus norvegicus	116-120
19818814-3	2010	By using the fusion expression with unique acid labile linker Asp-Pro and biochemical purification, the three novel GHRH peptides, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys, Pro-hGHRH(1-44)-Gly-Gly-Cys, and (1)Pro-GHRH(2-44)-Gly-Gly-Cys, were obtained.	Glycine	155-158	growth hormone releasing hormone	Rattus norvegicus	140-144
19936667-5	2010	TSHB gene sequencing revealed a homozygous missense mutation due to single base substitution G?A at codon 85 resulting in change from Glycine to Arginine.	Glycine	134-141	thyroid stimulating hormone subunit beta	Homo sapiens	0-4
19887446-5	2010	Our results show that a positively charged surface on NSF-N, bounded by Arg(67) and Lys(105), and the conserved residues in the central pore of NSF-D1 (Tyr(296) and Gly(298)) are involved in SNAP.SNARE binding but not basal ATP hydrolysis.	Glycine	165-168	N-ethylmaleimide sensitive factor, vesicle fusing ATPase	Homo sapiens	54-57
19247805-4	2009	One single nucleotide polymorphism (SNP) was detected in each gene (g. 149G&gt;T polymorphism in the porcine ANG gene, which resulted in an amino acid change from glycine to valine, g. 296A&gt;G polymorphism in the porcine RNASE1 gene and g. 389C&gt;T polymorphism in the porcine RNASE6 gene).	Glycine	163-170	ribonuclease K3	Sus scrofa	280-286
19552406-0	2009	Evaluation of a novel Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptide for potential melanoma therapy.	Glycine	26-29	pro-opiomelanocortin-alpha	Mus musculus	45-81
19719286-1	2009	The glycine zwitterion (GlyA) in the gas phase is not a local energy minimum and transforms to the canonical isomer (GlyB) via a barrierless process.	Glycine	4-11	Glycine auxotroph B, complementation of hamster	Homo sapiens	117-121
19719286-2	2009	Within ZSM-5 zeolite, it is rendered geometrically stable and even has a lower energy of 7.57 kcal mol(-1) than GlyC, the most stable isomer of glycine in the gas phase; GlyB represents the lowest energy minimum, which is facile to transform into the zwitterion with low-energy barrier (4.46 kcal mol(-1)).	Glycine	144-151	Glycine auxotroph B, complementation of hamster	Homo sapiens	170-174
19719286-4	2009	The relative stability of glycine isomers in silicalite-1 increases in the order GlyA&lt;GlyB&lt;GlyC, the same as that in the gas phase.	Glycine	26-33	Glycine auxotroph B, complementation of hamster	Homo sapiens	89-93
19422860-5	2009	The P949A was functionally restored by substitution with a glycine but not by the introduction of a proline at positions -1, -2 or +1, which indicates that P949 is structurally required for the normal functioning of the TRPA1 channel.	Glycine	59-66	transient receptor potential cation channel subfamily A member 1	Homo sapiens	220-225
19394328-6	2009	EC(50) values for glutamate at GluN1/GluN2A and glutamate and glycine at GluN1/GluN2B NMDA receptors were unaffected by the presence of ethanol.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	73-78
19394328-7	2009	We did however observe a small increase in glycine potency, in the presence of ethanol, at GluN1/GluN2A NMDA receptors.	Glycine	43-50	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	91-96
19434422-2	2009	The primary structure of AtGRP5 from Arabidopsis thaliana has a signal peptide followed by a region with high glycine content.	Glycine	110-117	glycine-rich protein 5	Arabidopsis thaliana	25-31
19468063-4	2009	CD1c presented an N-acyl glycine dodecamer peptide (lipo-12) to human T cells, and the response was specific for the acyl linkage as well as the peptide length and sequence.	Glycine	25-32	CD1c molecule	Homo sapiens	0-4
19463173-5	2009	RESULTS: Peptide 5nd (Tyr-Trp-c [Cys-Lys-Gly-Leu-Cys]-Lys-NH2, S-S) blocks the RGS4-Galphao interaction with an IC50 of 28 microM.	Glycine	41-44	regulator of G protein signaling 4	Homo sapiens	79-83
19463173-5	2009	RESULTS: Peptide 5nd (Tyr-Trp-c [Cys-Lys-Gly-Leu-Cys]-Lys-NH2, S-S) blocks the RGS4-Galphao interaction with an IC50 of 28 microM.	Glycine	41-44	G protein subunit alpha o1	Homo sapiens	84-91
19407372-2	2009	E2-25K is a dual-domain protein with an ubiquitin-associated (UBA) domain as well as a conserved ubiquitin-conjugating (UBC) domain which catalyzes the formation of a covalent bond between the C-terminal glycine of an ubiquitin molecule and the -amine of a lysine residue on the acceptor protein as part of the ubiquitin-proteasome pathway.	Glycine	204-211	ubiquitin C	Homo sapiens	120-123
18723115-3	2009	RAP55 proteins share multiple domains: the LSm14 domain, a serine/threonine rich region, an FDF (phenylalanine-aspartate-phenylalanine) motif, an FFD-TFG box and RGG (arginine-glycine-glycine) repeats.	Glycine	176-183	LSM14A mRNA processing body assembly factor	Homo sapiens	0-5
19345263-4	2009	LAIR-1 specifically interacts with synthetic trimeric peptides containing 10 repeats of glycine-proline-hydroxyproline (GPO) residues which can directly inhibit immune cell activation in vitro.	Glycine	88-95	leukocyte associated immunoglobulin like receptor 1	Homo sapiens	0-6
19357306-4	2009	We replaced the Gly-198 of Aurora-A with the equivalent residue Asn-142 of Aurora-B and found that in HeLa cells, Aurora-A(G198N) was recruited to the inner centromere in metaphase and the midzone in anaphase, reminiscent of the Aurora-B localization.	Glycine	16-19	aurora kinase A	Homo sapiens	27-35
19357306-4	2009	We replaced the Gly-198 of Aurora-A with the equivalent residue Asn-142 of Aurora-B and found that in HeLa cells, Aurora-A(G198N) was recruited to the inner centromere in metaphase and the midzone in anaphase, reminiscent of the Aurora-B localization.	Glycine	16-19	aurora kinase A	Homo sapiens	114-122
19357306-8	2009	Therefore, we propose that the presence of Gly or Asn at a single site assigns Aurora-A and -B to their respective partners and thus to their distinctive subcellular localizations and functions.	Glycine	43-46	aurora kinase A	Homo sapiens	79-94
19287951-6	2009	Similarly, BRCA1 cancer-predisposing mutation (61Cys-Gly) abrogated the ability to both bind Ubc9 as well as inhibit ERalpha activity suggesting physiological significance.	Glycine	53-56	ubiquitin conjugating enzyme E2 I	Homo sapiens	93-97
19127222-6	2009	In patient 2, we identified a novel missense mutation, c.1141G&gt;C, in exon 9, which led to a substitution of glycine with arginine in the TNFL domain of EDA (p.G381R).	Glycine	111-118	ectodysplasin A	Homo sapiens	155-158
19258348-6	2009	Collectively, these results showed that CSDP1 and CSDP2 perform different functions in seed germination and growth of Arabidopsis under stress conditions, and that the glycine-rich region interspersed with CCHC-type zinc fingers is particularly important for its nucleic acid-binding activities and function.	Glycine	168-175	glycine rich protein 2	Arabidopsis thaliana	50-55
20641511-12	2004	The tumor homing peptide cyclo(Cys-Asn-Gly-Arg-Cys)-Gly-Lys (cNGR) contains the Asn-Gly-Arg (NGR) motif that binds to APN (12).	Glycine	39-42	alanyl aminopeptidase, membrane	Homo sapiens	118-121
20641511-12	2004	The tumor homing peptide cyclo(Cys-Asn-Gly-Arg-Cys)-Gly-Lys (cNGR) contains the Asn-Gly-Arg (NGR) motif that binds to APN (12).	Glycine	52-55	alanyl aminopeptidase, membrane	Homo sapiens	118-121
20641652-12	2004	The tumor homing peptide cyclo(Cys-Asn-Gly-Arg-Cys)-Gly-Lys (cNGR) contains the Asn-Gly-Arg (NGR) motif that binds to APN (12).	Glycine	39-42	alanyl aminopeptidase, membrane	Homo sapiens	118-121
20641652-12	2004	The tumor homing peptide cyclo(Cys-Asn-Gly-Arg-Cys)-Gly-Lys (cNGR) contains the Asn-Gly-Arg (NGR) motif that binds to APN (12).	Glycine	52-55	alanyl aminopeptidase, membrane	Homo sapiens	118-121
19114063-3	2009	Our previous work demonstrated that targeted disruption of mouse Phgdh leads to a marked decrease in serine and glycine, severe growth retardation of the central nervous system, and lethality after embryonic day 13.5.	Glycine	112-119	3-phosphoglycerate dehydrogenase	Mus musculus	65-70
18803481-5	2009	To manipulate EC adhesion, migration, and tubulogenesis, the surface of PEGDA hydrogels was micropatterned with a cell adhesive ligand, Arg-Gly-Asp-Ser (RGDS), in desired concentrations and geometries.	Glycine	140-143	ral guanine nucleotide dissociation stimulator	Homo sapiens	153-157
18845625-5	2009	Treatment of NOD mice with a glucagon-like peptide 2 (GLP-2) analog, synthetic human [Gly(2)] glucagon-like peptide-2 (h[Gly(2)]GLP-2, increased the length and weight of the small bowel and significantly improved jejunal transepithelial resistance.	Glycine	86-89	glucagon-like peptide 2 receptor	Mus musculus	29-52
18845625-5	2009	Treatment of NOD mice with a glucagon-like peptide 2 (GLP-2) analog, synthetic human [Gly(2)] glucagon-like peptide-2 (h[Gly(2)]GLP-2, increased the length and weight of the small bowel and significantly improved jejunal transepithelial resistance.	Glycine	121-124	glucagon-like peptide 2 receptor	Mus musculus	29-52
18845625-8	2009	These findings demonstrate that h[Gly(2)]GLP-2-mediated enhancement of gut barrier function in normoglycemic NOD mice disease is not sufficient to prevent or delay the development of experimental T1D.	Glycine	34-37	glucagon-like peptide 2 receptor	Mus musculus	41-46
18824844-8	2009	The analysis of mRNA expressions of Th1 (t-bet, TNF-alpha, IL-1beta) and Th2 (gata-3, IL-4, IL-10) cytokines showed a Th1-polarized response in Gly-AKI rats that was aggravated with the anti-HGF treatment.	Glycine	144-147	interleukin 4	Rattus norvegicus	86-90
18487077-1	2009	The aim of this study was to investigate the predisposition of the FGFR4 Gly/Arg polymorphism for development of head and neck squamous cell carcinoma (HNSCC) and, furthermore, to examine if the FGFR4 Arg(388) allele can be associated with resistance to chemo- and radiotherapy.	Glycine	73-76	fibroblast growth factor receptor 4	Homo sapiens	67-72
19601911-1	2009	The N-terminal 25 residue segment of human surfactant protein B (SP-B(1-25)) was synthesised in 26% yield by manual Fmoc solid-phase peptide synthesis (Fmoc SPPS) using low-loading Fmoc-Gly-Wang resin.	Glycine	186-189	surfactant protein B	Homo sapiens	43-63
19365107-2	2009	The T allele missense mutation results in the 80th amino acid of the PLA2G2D protein changing from a glycine (Gly; C allele) to a serine (Ser; T allele).	Glycine	101-108	phospholipase A2 group IID	Homo sapiens	69-76
19365107-2	2009	The T allele missense mutation results in the 80th amino acid of the PLA2G2D protein changing from a glycine (Gly; C allele) to a serine (Ser; T allele).	Glycine	110-113	phospholipase A2 group IID	Homo sapiens	69-76
19365107-6	2009	METHODS: A549 cells (a human pulmonary epithelial cell line) were transfected with PLA2G2D-Gly or PLA2G2D-Ser.	Glycine	91-94	phospholipase A2 group IID	Homo sapiens	83-90
21965354-10	2011	In the perioperative setting, this has specifically been demonstrated for the Arg389Gly beta1AR polymorphism with which patients with the Gly variant had a higher incidence of adverse perioperative events.	Glycine	84-87	adrenoceptor beta 1	Homo sapiens	88-95
21971830-5	2011	Thus, after hours or days of relaxin treatment, respectively, arterial MMP-9 or MMP-2 hydrolyze "big" endothelin (ET) at a gly-leu bond to form ET(1-32), which in turn activates the endothelial ET(B) receptor/nitric oxide vasodilatory pathway.	Glycine	123-126	matrix metallopeptidase 2	Rattus norvegicus	80-85
21885653-2	2011	Here, we generated transgenic (Tg) mice expressing the A57G (alanine to glycine) mutation in the cardiac ELC known to cause familial hypertrophic cardiomyopathy (FHC).	Glycine	72-79	myosin, light polypeptide 4	Mus musculus	105-108
22174695-2	2011	Here we show that a single nucleotide germline polymorphism (SNP) substituting an arginine (R) for glycine (G) in the FGFR4 transmembrane domain can alter pituitary cell growth and hormone production.	Glycine	99-106	fibroblast growth factor receptor 4	Homo sapiens	118-123
21910806-2	2011	The neuronal glycine transporter 2 (GLYT2) supplies the terminal with substrate to refill synaptic vesicles containing glycine.	Glycine	13-20	solute carrier family 6 member 5	Homo sapiens	36-41
21822533-5	2011	siRNA-mediated reduction of fibronectin and interference in the liaison between fibronectin and integrins by the Arg-Gly-Asp-Ser (RGDS) peptide increased aggrecan expression, and decreased versican expression by TGF-beta1 stimulation.	Glycine	117-120	transforming growth factor, beta 1	Mus musculus	212-221
21668429-12	2011	Molecular modelling showed that glycine 170 is located on the dimer interface of UROD, in a loop containing residues 167-172 that are critical for optimal enzymatic activity and that the carboxyl side chain from aspartic acid is predicted to cause negative interactions between the protein and the substrate.	Glycine	32-39	uroporphyrinogen decarboxylase	Homo sapiens	81-85
21847098-4	2011	PIKE-L directly interacts with both GluA2 and GRIP1 and forms a tertiary complex upon glycine-induced NMDA receptor activation.	Glycine	86-93	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	Homo sapiens	0-4
21847098-4	2011	PIKE-L directly interacts with both GluA2 and GRIP1 and forms a tertiary complex upon glycine-induced NMDA receptor activation.	Glycine	86-93	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	36-41
21847098-5	2011	PIKE-L is also essential for glycine-induced GluA2-associated PI3K activation.	Glycine	29-36	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	Homo sapiens	0-4
21847098-5	2011	PIKE-L is also essential for glycine-induced GluA2-associated PI3K activation.	Glycine	29-36	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	45-50
21927680-11	2011	In the case of beta(1)AR-49, the QTc interval change immediately after tracheal intubation was significantly greater in Ser/Ser genotypes than in Ser/Gly genotypes.	Glycine	150-153	adrenoceptor beta 1	Homo sapiens	15-24
21852955-8	2011	Sex-specific genome-wide association studies (GWAS) showed genome-wide significant differences in beta-estimates for SNPs in the CPS1 locus (carbamoyl-phosphate synthase 1, significance level: p&lt;3.8x10(-10); Bonferroni-corrected threshold) for glycine.	Glycine	247-254	carbamoyl-phosphate synthase 1	Homo sapiens	129-133
21622724-2	2011	Furthermore, a germ line polymorphism in the FGFR-4 gene, resulting in arginine at codon 388 (Arg388) instead of glycine (Gly388), is associated with aggressive disease.	Glycine	113-120	fibroblast growth factor receptor 4	Homo sapiens	45-51
21719841-7	2011	Analysis of the deduced amino acids of the viral hemagglutinin revealed a glycine (G) and a tyrosine (Y) at amino acid positions 530 and 549, respectively, of the partial signaling lymphocytic activation molecule (SLAM)-receptor binding region which is typically found in viral strains obtained from domestic dogs.	Glycine	74-81	signaling lymphocytic activation molecule family member 1	Canis lupus familiaris	171-212
21719841-7	2011	Analysis of the deduced amino acids of the viral hemagglutinin revealed a glycine (G) and a tyrosine (Y) at amino acid positions 530 and 549, respectively, of the partial signaling lymphocytic activation molecule (SLAM)-receptor binding region which is typically found in viral strains obtained from domestic dogs.	Glycine	74-81	signaling lymphocytic activation molecule family member 1	Canis lupus familiaris	214-218
21474449-6	2011	Nucleolin contains a long (~300 amino acids) intrinsically unstructured region, followed by the four tandem RNA recognition motifs and the C-terminal glycine/arginine-rich domain.	Glycine	150-157	nucleolin	Homo sapiens	0-9
21561087-3	2011	We recently reported that the Arg-Gly-Gly repeat (RGG) of the C-terminus in Ewing"s sarcoma protein (EWS), which is a group of dominant oncogenes that arise due to chromosomal translocations, is capable of binding to G-quadruplex telomere DNA and RNA via arginine residues and stabilize the G-quadruplex DNA form in vitro.	Glycine	34-37	EWS RNA binding protein 1	Homo sapiens	101-104
21561087-3	2011	We recently reported that the Arg-Gly-Gly repeat (RGG) of the C-terminus in Ewing"s sarcoma protein (EWS), which is a group of dominant oncogenes that arise due to chromosomal translocations, is capable of binding to G-quadruplex telomere DNA and RNA via arginine residues and stabilize the G-quadruplex DNA form in vitro.	Glycine	38-41	EWS RNA binding protein 1	Homo sapiens	101-104
21244633-3	2011	Here we show that the Arg-Gly-Gly (RGG) domain of the C-terminal in EWS binds to the G-rich single-stranded DNA and RNA fold in the G-quadruplex structure.	Glycine	26-29	EWS RNA binding protein 1	Homo sapiens	68-71
21244633-3	2011	Here we show that the Arg-Gly-Gly (RGG) domain of the C-terminal in EWS binds to the G-rich single-stranded DNA and RNA fold in the G-quadruplex structure.	Glycine	30-33	EWS RNA binding protein 1	Homo sapiens	68-71
21184736-3	2011	HnRNP K is methylated at multiple sites in the glycine- and arginine-rich (RGG) motif.	Glycine	47-54	heterogeneous nuclear ribonucleoprotein K	Homo sapiens	0-7
21264295-6	2011	(1) Mutations of Glu(896), Leu(899), Gly(904) in extracellular loop Domain II S3-S4 of DmNa(v)1 abolished the functional action of BmK IT2.	Glycine	37-40	paralytic	Drosophila melanogaster	87-95
20561964-7	2010	Co-injecting GLY with 7-chlorokynurenic acid (7-CLK) or (+/-)-3-amino-1-hydroxy-2-pyrrolidone (HA-966) completely prevented the GLY effects in incapacitation and paw shacking tests, respectively.	Glycine	13-16	CDC like kinase 1	Homo sapiens	48-51
21054786-9	2010	This low activity could be explained by the fact that PRTFDC1 has a Gly in the position of the proposed catalytic Asp of HPRT.	Glycine	68-71	hypoxanthine phosphoribosyltransferase 1	Homo sapiens	121-125
20735721-9	2010	FVIII bound to Glu-Gly-Arg-active-site-modified FVIIa (K(d), ~0.8 nM) with a higher affinity for the HCh than for the LCh (K(d), 5.9 and 18.9 nm).	Glycine	19-22	coagulation factor VIII	Homo sapiens	0-5
20688135-6	2010	Tyr at position 5 broadens the NR2 selectivity, and recovery of NR2B selectivity in Tyr5 peptides was achieved by incorporating Ala or Gly at position 8.	Glycine	135-138	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	64-68
20542917-2	2010	Here, we present the size variation and evolution of the nucleotide-binding site (NBS)-encoding gene family and receptor-like kinase (RLK) gene family in Oryza, Glycine and Gossypium.	Glycine	161-168	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	57-80
20542917-2	2010	Here, we present the size variation and evolution of the nucleotide-binding site (NBS)-encoding gene family and receptor-like kinase (RLK) gene family in Oryza, Glycine and Gossypium.	Glycine	161-168	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	82-85
20530479-7	2010	We also report that the ubiquitin ligase Nedd4-2 interacts with Na(v)1.6 via a Pro-Ser-Tyr(1945) motif in the C terminus of the channel and reduces Na(v)1.6 current density, and we show that this regulation requires both the Pro-Gly-Ser-Pro motif in L1 and the Pro-Ser-Tyr motif in the C terminus.	Glycine	229-232	sodium channel, voltage-gated, type VIII, alpha	Mus musculus	64-72
20530479-7	2010	We also report that the ubiquitin ligase Nedd4-2 interacts with Na(v)1.6 via a Pro-Ser-Tyr(1945) motif in the C terminus of the channel and reduces Na(v)1.6 current density, and we show that this regulation requires both the Pro-Gly-Ser-Pro motif in L1 and the Pro-Ser-Tyr motif in the C terminus.	Glycine	229-232	sodium channel, voltage-gated, type VIII, alpha	Mus musculus	148-156
20452985-4	2010	The combination of the APP-GxxxG mutation G33A with APP-FAD mutations yielded a constant 60% decrease of Abeta42 levels and a concomitant 3-fold increase of Abeta38 levels compared with the Gly(33) wild-type as determined by ELISA.	Glycine	190-193	presenilin 1	Homo sapiens	56-59
20518521-0	2010	Disease-associated mutations in the p150(Glued) subunit destabilize the CAP-gly domain.	Glycine	76-79	chromatin assembly factor 1 subunit A	Homo sapiens	36-40
20518521-1	2010	Point mutations within the CAP-gly domain of the p150(Glued) subunit of the dynactin complex have been identified in patients with distal spinal bulbar muscular atrophy (dSBMA) and Perry"s syndrome.	Glycine	31-34	chromatin assembly factor 1 subunit A	Homo sapiens	49-71
20495767-3	2010	Previous studies have shown that catalase binds to A-beta fibrils and appears to recognize a region containing the Gly-Ala-Ile-Ile sequence that is similar to the Gly-Ala-Ile-Leu sequence found in human IAPP residues 24-27.	Glycine	115-118	islet amyloid polypeptide	Homo sapiens	203-207
20495767-3	2010	Previous studies have shown that catalase binds to A-beta fibrils and appears to recognize a region containing the Gly-Ala-Ile-Ile sequence that is similar to the Gly-Ala-Ile-Leu sequence found in human IAPP residues 24-27.	Glycine	163-166	islet amyloid polypeptide	Homo sapiens	203-207
20495767-10	2010	For IAPP 1-37 and 8-37, the catalase binding was primarily directed towards fibrillar rather than ribbon-like structures, suggesting differences in the accessibility of the human IAPP 24-27 Gly-Ala-Ile-Leu region.	Glycine	190-193	islet amyloid polypeptide	Homo sapiens	4-8
20495767-10	2010	For IAPP 1-37 and 8-37, the catalase binding was primarily directed towards fibrillar rather than ribbon-like structures, suggesting differences in the accessibility of the human IAPP 24-27 Gly-Ala-Ile-Leu region.	Glycine	190-193	islet amyloid polypeptide	Homo sapiens	179-183
20067760-4	2010	Here, we investigated the role of the Gly residues in the S2-S3 linkers of domains I and II of Ca(v)1.2.	Glycine	38-41	immunoglobulin lambda variable 2-8	Homo sapiens	95-103
20153823-2	2010	ISG15 is synthesized as a precursor in certain mammals and, therefore, needs to be processed to expose the C-terminal glycine residue before conjugation to target proteins.	Glycine	118-125	ISG15 ubiquitin like modifier	Homo sapiens	0-5
20235117-10	2010	Results demonstrated that the peptide 3C (H-Tyr-Ile-Glu-Gly-Leu-Gln-Ala-Leu-Leu-Arg-Asp-Gln-NH(2)) not only showed high affinity for Id1 but also exhibited antiproliferative effects in HT-29 and MCF-7 cancer cells; the IC(50) value of 3C was determined as 25 microM in both cells.	Glycine	56-59	inhibitor of DNA binding 1, HLH protein	Homo sapiens	133-136
20007704-3	2010	Specifically, residues Gly(170)-Gln(185) of the beta2-subunit were mutated to alanine, co-expressed with wild-type alpha1- and gamma2S-subunits in human embryonic kidney (HEK) 293 cells and assayed for their activation by GABA, the intravenous anesthetic propofol and the endogenous neurosteroid pregnanolone using whole cell macroscopic recordings.	Glycine	23-26	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	48-61
19468822-2	2010	In plants, some amino acids work as buffers: during photorespiration, ammonium derived from the conversion of glycine to serine is promptly reassimilated into glutamate by the glutamine synthetase (GS-2)/ferredoxin-dependent glutamate synthase (Fd-GOGAT) cycle.	Glycine	110-117	glutamate synthase 1	Arabidopsis thaliana	204-243
19918264-2	2010	A single nucleotide polymorphism at position 388 of the FGFR4 amino-acid sequence results in the substitution of glycine (Gly) with arginine (Arg) and higher frequency of the ArgArg genotype was previously found in prostate cancer patients.	Glycine	113-120	fibroblast growth factor receptor 4	Homo sapiens	56-61
19918264-2	2010	A single nucleotide polymorphism at position 388 of the FGFR4 amino-acid sequence results in the substitution of glycine (Gly) with arginine (Arg) and higher frequency of the ArgArg genotype was previously found in prostate cancer patients.	Glycine	122-125	fibroblast growth factor receptor 4	Homo sapiens	56-61
20008324-8	2010	Fluorescence spectroscopy and nuclear magnetic resonance studies in the presence of the cytoskeleton-associated protein-glycine-rich domains of either CLIP-170 or p150(glued) or of a fragment derived from the adenomatous polyposis coli tumor suppressor protein show that chain exchange of EBc domains can be controlled by binding partners.	Glycine	120-127	chromatin assembly factor 1 subunit A	Homo sapiens	163-174
20161733-5	2010	In the current study, we took advantage of intrinsic proline-glycine (Pro-Gly) dipeptides encoded in predicted DAT extracellular domains to introduce tetraCys motifs into DAT extracellular loops 2, 3, and 4.	Glycine	61-68	solute carrier family 6 member 3	Rattus norvegicus	111-114
20161733-5	2010	In the current study, we took advantage of intrinsic proline-glycine (Pro-Gly) dipeptides encoded in predicted DAT extracellular domains to introduce tetraCys motifs into DAT extracellular loops 2, 3, and 4.	Glycine	61-68	solute carrier family 6 member 3	Rattus norvegicus	171-174
19033659-6	2008	Additional mutations were identified in the genes encoding the putative glycine transporter SLC6A18 (XT2) and the neutral amino acid transporter SLC6A19 (B0AT1) in families with either IG or HG, suggesting that mutations in the genes encoding these transporters may also contribute to these phenotypes.	Glycine	72-79	solute carrier family 6 member 18	Homo sapiens	101-104
18959747-3	2008	This study describes mutant forms of thimet oligopeptidase in which Gly or Tyr residues in the 599-611 loop region were replaced, individually and in combination, to elucidate the mechanism of substrate selection by this enzyme.	Glycine	68-71	thimet oligopeptidase 1	Homo sapiens	37-58
26247835-11	2016	In addition, Phe-231 and Gly-329 were found to interact with pyrene to orient this compound in the active site of P450 1B1.	Glycine	25-28	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	114-122
18723025-4	2008	Type I Hsp40s contain a conserved, centrally located cysteine-rich domain that is replaced by a glycine- and methionine-rich region in Type II Hsp40s, but the mechanism by which these unique domains influence Hsp40 structure and function is unknown.	Glycine	96-103	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	7-12
18723025-4	2008	Type I Hsp40s contain a conserved, centrally located cysteine-rich domain that is replaced by a glycine- and methionine-rich region in Type II Hsp40s, but the mechanism by which these unique domains influence Hsp40 structure and function is unknown.	Glycine	96-103	DnaJ heat shock protein family (Hsp40) member B1	Homo sapiens	143-148
19755481-4	2010	LHRH-I is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15) that cleaves the hormone at the fifth and sixth bond of the decapeptide (Tyr(5)-Gly(6)) to form LHRH-(1-5).	Glycine	154-157	gonadotropin releasing hormone 1	Homo sapiens	0-6
19755481-4	2010	LHRH-I is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15) that cleaves the hormone at the fifth and sixth bond of the decapeptide (Tyr(5)-Gly(6)) to form LHRH-(1-5).	Glycine	154-157	gonadotropin releasing hormone 1	Homo sapiens	0-4
26656683-0	2016	Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice.	Glycine	0-7	polybromo 1	Mus musculus	27-30
20596833-4	2010	From a comparison of total energy, stabilizing residues and RMSD of these three mutant proteins with native pRB protein, we identified that the major mutation is from Glutamic acid to Glycine at the residue position of 746 of pRB.	Glycine	184-191	RB transcriptional corepressor 1	Homo sapiens	108-111
20596833-4	2010	From a comparison of total energy, stabilizing residues and RMSD of these three mutant proteins with native pRB protein, we identified that the major mutation is from Glutamic acid to Glycine at the residue position of 746 of pRB.	Glycine	184-191	RB transcriptional corepressor 1	Homo sapiens	226-229
18664566-5	2008	The carboxyl-terminal glycine residue of Urm1 was critical for the s(2) modification, indicating direct involvement of the unique ubiquitin-related system in this process.	Glycine	22-29	ubiquitin-related modifier URM1	Saccharomyces cerevisiae S288C	41-45
26656683-5	2016	We further demonstrated that the mutation of glycine (G) to aspartic acid (D) at position 622 in PB1 partially impaired the binding of PB1 to viral RNA, thereby dramatically decreasing the polymerase activity and attenuating H5N1 virus virulence in mice.	Glycine	45-52	polybromo 1	Mus musculus	97-100
26656683-5	2016	We further demonstrated that the mutation of glycine (G) to aspartic acid (D) at position 622 in PB1 partially impaired the binding of PB1 to viral RNA, thereby dramatically decreasing the polymerase activity and attenuating H5N1 virus virulence in mice.	Glycine	45-52	polybromo 1	Mus musculus	135-138
26656683-11	2016	We found that the mutation of glycine (G) to aspartic acid (D) at position 622 in PB1 partially impairs the binding of PB1 to viral RNA, thereby attenuating H5N1 virus virulence in mice.	Glycine	30-37	polybromo 1	Mus musculus	82-85
26656683-11	2016	We found that the mutation of glycine (G) to aspartic acid (D) at position 622 in PB1 partially impairs the binding of PB1 to viral RNA, thereby attenuating H5N1 virus virulence in mice.	Glycine	30-37	polybromo 1	Mus musculus	119-122
19917615-3	2010	Pax6 contains two DNA binding domains (paired domain and homeodomain), a glycine-rich linker connecting these two domains and a C-terminal proline-, serine-, and threonine-rich transactivation domain.	Glycine	73-80	paired box 6	Homo sapiens	0-4
18697746-8	2008	Notably, the linkage tetrasaccharide-peptide GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-(Gly)Ser-(Gly-Glu) was a good acceptor substrate for the C6ST-1, suggesting that the sulfation of the galactose residues can occur before the transfer of the first N-acetylhexosamine residue to the linkage tetrasaccharide.	Glycine	89-92	carbohydrate sulfotransferase 3	Homo sapiens	145-151
19617589-0	2010	Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.	Glycine	14-21	insulin-induced gene 2 protein	Cricetulus griseus	50-57
26542286-1	2015	Creatine is physiologically provided equally by diet and by endogenous synthesis from arginine and glycine with successive involvements of arginine glycine amidinotransferase [AGAT] and guanidinoacetate methyl transferase [GAMT].	Glycine	99-106	guanidinoacetate N-methyltransferase	Homo sapiens	223-227
19617589-7	2010	This glycine residue localizes to the first membrane-spanning segment of Insig-2 and is also present in the corresponding region of Insig-1.	Glycine	5-12	insulin-induced gene 2 protein	Cricetulus griseus	73-80
19799950-0	2010	Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis.	Glycine	70-77	ATPase inhibitor A, mitochondrial	Drosophila virilis	56-60
19799950-4	2010	SK84 contains a high level of glycine (15.5%) and a hexaglycine cluster motif in the N-terminal part.	Glycine	30-37	ATPase inhibitor A, mitochondrial	Drosophila virilis	0-4
19799950-9	2010	Our results show that SK84 represents a novel glycine-rich peptide family in Drosophila species with antimicrobial and anti-cancer cell activities.	Glycine	46-53	ATPase inhibitor A, mitochondrial	Drosophila virilis	22-26
18779583-2	2008	The role of glycine-binding NR3 subunits is less clear.	Glycine	12-19	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	28-31
18698489-1	2008	EWS, a pro-oncoprotein which is encoded by the Ewing sarcoma (EWS) gene, contains arginine-glycine-glycine repeats (RGG box) in its COOH-terminus.	Glycine	91-98	EWS RNA binding protein 1	Homo sapiens	0-3
18698489-1	2008	EWS, a pro-oncoprotein which is encoded by the Ewing sarcoma (EWS) gene, contains arginine-glycine-glycine repeats (RGG box) in its COOH-terminus.	Glycine	91-98	EWS RNA binding protein 1	Homo sapiens	62-65
18621031-4	2008	GlyT1 inhibitors ALX 5407 and sarcosine reduced total glycine uptake to 80% whereas the specific GlyT2 inhibitor Org 25543 had no effect.	Glycine	54-61	hematopoietic SH2 domain containing	Homo sapiens	17-20
19819873-2	2009	Multiple sequence alignment of human M1 aminopeptidase revealed that the first Gly residue within the conserved exopeptidase motif of the M1 family, GXMEN motif, is uniquely substituted for His in human LVRN/APQ.	Glycine	79-82	laeverin	Homo sapiens	203-211
26482881-4	2015	We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production.	Glycine	61-68	phosphoglycerate dehydrogenase	Homo sapiens	95-100
26482881-4	2015	We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production.	Glycine	61-68	phosphoserine aminotransferase 1	Homo sapiens	102-107
20011517-5	2009	Genetic mapping revealed a mutation resulting in a glycine to arginine change in the catalytic domain of the aldh1a2 gene, which is required for the production of retinoic acid from vitamin A.	Glycine	51-58	aldehyde dehydrogenase 1 family, member A2	Danio rerio	109-116
26703626-6	2015	We found that SH, M-Gly, and P334 have significant effects on the wound healing process in human keratinocytes and these effects were mediated by activation of focal adhesion kinases (FAK), extracellular signal-regulated kinases (ERK), and c-Jun N-terminal kinases (JNK).	Glycine	20-23	protein tyrosine kinase 2	Homo sapiens	160-182
18573508-1	2008	In the present study, genotype and haplotype frequencies of four polymorphisms of cytochrome P450 1B1 (CYP1B1) that cause amino acid changes (Arg-Gly at codon 48, Ala-Ser at codon 119, Leu-Val at 432 and Asn-Ser at codon 453) were studied in 200 patients suffering from lung cancer and equal number of controls.	Glycine	146-149	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	82-101
18573508-1	2008	In the present study, genotype and haplotype frequencies of four polymorphisms of cytochrome P450 1B1 (CYP1B1) that cause amino acid changes (Arg-Gly at codon 48, Ala-Ser at codon 119, Leu-Val at 432 and Asn-Ser at codon 453) were studied in 200 patients suffering from lung cancer and equal number of controls.	Glycine	146-149	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	103-109
26703626-6	2015	We found that SH, M-Gly, and P334 have significant effects on the wound healing process in human keratinocytes and these effects were mediated by activation of focal adhesion kinases (FAK), extracellular signal-regulated kinases (ERK), and c-Jun N-terminal kinases (JNK).	Glycine	20-23	protein tyrosine kinase 2	Homo sapiens	184-187
26506308-5	2015	Expression of the microtubule-anchoring CAP-GLY domain of CLIP170 fused to the nuclear-envelope-anchoring KASH domain of nesprin rescues nuclear positioning defects of amph-1 mutants.	Glycine	44-47	amphiphysin	Homo sapiens	168-174
18365190-6	2008	The transmembrane domain of ErbB3 impairs this C-terminal motif but also associates with the other partners owing to the presence of Gly residues.	Glycine	133-136	erb-b2 receptor tyrosine kinase 3	Homo sapiens	28-33
26615663-12	2015	A higher CAP class for birch pollen, Bet v 1, Gly m 4, and soybean was associated with a higher prevalence of OAS to soy milk.	Glycine	46-49	SPARC related modular calcium binding 1	Homo sapiens	110-113
19099814-16	2008	CONCLUSIONS: From the clinical course, obvious elevation of blood C5-carnitine and urine isovaleric glycine, this patient"s disorder should be classified as "metabolically severe" type of IVA which suggest that c.466G &gt; C (G127A) mutation could severely damage the function of the IVD protein.	Glycine	100-107	isovaleryl-CoA dehydrogenase	Homo sapiens	284-287
26086092-3	2015	It was found that polyamines, especially spermidine, can permeate NMDA channels expressed from GluN1/GluN2A or GluN1/GluN2B activated by glycine and glutamate.	Glycine	137-144	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	117-123
26067360-7	2015	They also showed an exercise-induced compensatory regulation of genes involved in biosynthesis and metabolism of amino acids (PSPH, GATM, NOS1 and GLDC), which responded to differences in the amino acid profile (consistently lower plasma levels of glycine, cysteine and arginine).	Glycine	248-255	nitric oxide synthase 1	Homo sapiens	138-142
18413312-6	2008	Here we report that expression of a recombinant 44-MT1 (Gly(285)-Val(582)) in HT1080 fibrosarcoma cells results in enhanced pro-MMP-2 activation, proliferation within a three-dimensional collagen I matrix, and tumor growth and lung metastasis in mice.	Glycine	56-59	matrix metallopeptidase 2	Homo sapiens	128-133
26067360-7	2015	They also showed an exercise-induced compensatory regulation of genes involved in biosynthesis and metabolism of amino acids (PSPH, GATM, NOS1 and GLDC), which responded to differences in the amino acid profile (consistently lower plasma levels of glycine, cysteine and arginine).	Glycine	248-255	glycine decarboxylase	Homo sapiens	147-151
26046984-8	2015	As a result, in Xenopus laevis oocytes injected with cRNA encoding PEPT1 or PEPT2, but not in oocytes injected with water or with USP18 alone, application of the dipeptide gly-gly (2 mM) was followed by the appearance of an inward current (Igly-gly).	Glycine	172-175	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	67-72
26046984-8	2015	As a result, in Xenopus laevis oocytes injected with cRNA encoding PEPT1 or PEPT2, but not in oocytes injected with water or with USP18 alone, application of the dipeptide gly-gly (2 mM) was followed by the appearance of an inward current (Igly-gly).	Glycine	172-175	solute carrier family 15 member 2 L homeolog	Xenopus laevis	76-81
26046984-9	2015	Coexpression of USP18 significantly increased Igly-gly in both PEPT1 and PEPT2 expressing oocytes.	Glycine	47-50	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	63-68
26046984-12	2015	Coexpression of USP30 similarly increased Igly-gly in PEPT1 expressing oocytes.	Glycine	43-46	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	54-59
25687974-0	2015	A refined atomic scale model of the Saccharomyces cerevisiae K+-translocation protein Trk1p combined with experimental evidence confirms the role of selectivity filter glycines and other key residues.	Glycine	168-176	Trk1p	Saccharomyces cerevisiae S288C	86-91
25710242-3	2015	RECENT FINDINGS: Strategies focused on enhancing activity of the N-methyl D-aspartate (NMDA) receptor via direct agonists at the glycine site or by inhibition of glycine reuptake have produced modest and often inconsistent evidence of efficacy, as have approaches to reduce excessive glutamate release by lamotrigine or by mGluR2/3 agonists.	Glycine	129-136	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	323-329
24249517-0	2015	Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: an Arg-Gly-Asp-dependent-focal adhesion kinase-caspase-8 axis.	Glycine	115-118	secreted phosphoprotein 1	Mus musculus	0-11
25680633-2	2015	To improve cell attachment, arginine-glycine-aspartic acid-serine (RGDS) peptides were covalently grafted to chitosan films, through the widely used coupling agents 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC-HCl) and N-hydroxysuccinimide (NHS), via the carboxylic acid function of the RGDS molecule.	Glycine	37-44	ral guanine nucleotide dissociation stimulator	Homo sapiens	67-71
25520403-9	2015	Further, we performed an amino acid competition assay and found that two amino acids, alanine and glycine, known as substrates of LHT1, could suppress the ACC-induced triple response in a LHT1-dependent way.	Glycine	98-105	lysine histidine transporter 1	Arabidopsis thaliana	130-134
25520403-9	2015	Further, we performed an amino acid competition assay and found that two amino acids, alanine and glycine, known as substrates of LHT1, could suppress the ACC-induced triple response in a LHT1-dependent way.	Glycine	98-105	lysine histidine transporter 1	Arabidopsis thaliana	188-192
25619998-5	2015	Ser1 and Arg3 of the histone make extensive contacts to highly conserved NatD residues in the substrate binding pocket, and flanking glycine residues also appear to contribute to substrate-specific binding by NatD, together defining a Ser-Gly-Arg-Gly recognition sequence.	Glycine	133-140	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	209-213
25619998-5	2015	Ser1 and Arg3 of the histone make extensive contacts to highly conserved NatD residues in the substrate binding pocket, and flanking glycine residues also appear to contribute to substrate-specific binding by NatD, together defining a Ser-Gly-Arg-Gly recognition sequence.	Glycine	239-242	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	73-77
25619998-5	2015	Ser1 and Arg3 of the histone make extensive contacts to highly conserved NatD residues in the substrate binding pocket, and flanking glycine residues also appear to contribute to substrate-specific binding by NatD, together defining a Ser-Gly-Arg-Gly recognition sequence.	Glycine	239-242	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	209-213
25619998-5	2015	Ser1 and Arg3 of the histone make extensive contacts to highly conserved NatD residues in the substrate binding pocket, and flanking glycine residues also appear to contribute to substrate-specific binding by NatD, together defining a Ser-Gly-Arg-Gly recognition sequence.	Glycine	247-250	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	73-77
25619998-5	2015	Ser1 and Arg3 of the histone make extensive contacts to highly conserved NatD residues in the substrate binding pocket, and flanking glycine residues also appear to contribute to substrate-specific binding by NatD, together defining a Ser-Gly-Arg-Gly recognition sequence.	Glycine	247-250	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	209-213
25463493-3	2015	In this study, surfaces with the mobile Arg-Gly-Asp-Ser (RGDS) peptide have been constructed.	Glycine	44-47	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	57-61
25406939-5	2015	The specific OTR agonist [Thr(4),Gly(7)]-oxytocin acutely stimulated the release of LH, GH, and prolactin from female rat pituitary cells in primary culture and increased intracellular Ca(2+) concentration in gonadotrophs, somatotrophs, and lactotrophs.	Glycine	33-36	oxytocin receptor	Rattus norvegicus	13-16
25468444-3	2015	IGFBP-1 and IGFBP-2 have a C-terminal Arg-Gly-Asp (RGD) sequence, and IGFBP-1 has been shown by others to stimulate migration through binding of its RGD sequence to alpha5beta1 integrin.	Glycine	42-45	insulin like growth factor binding protein 2	Homo sapiens	12-19
19744956-3	2009	Myristoylation of SH3TC2 in glycine 2 is necessary but not sufficient for the proper location of the protein in the cell membranes.	Glycine	28-35	SH3 domain and tetratricopeptide repeats 2	Homo sapiens	18-24
19726695-6	2009	However, robust glycine-activated currents were generated in cells transfected with NR3(A or B) and either NR1-2a, NR1-3a, or NR1-4a, and current density was correlated with NR1 C-terminal length.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	84-94
25480793-5	2015	GlyT2 mediates synaptic glycine recycling, which constitutes the main source of releasable transmitter at glycinergic synapses.	Glycine	24-31	solute carrier family 6 member 5	Homo sapiens	0-5
19819988-8	2009	Pretreatment of MG63 cells with Arg-Gly-Asp-Ser, which blocks the cell-extracellular matrix interaction, or transfection with beta(3) integrin-specific siRNA inhibited BMP-4-induced ERK and Smad1/5 phosphorylations.	Glycine	36-39	bone morphogenetic protein 4	Homo sapiens	168-173
25569235-9	2015	GWAS replicated three known loci in the metabolome wide significance: CPS1 with glycine (P-value  = 1.27x10-32), PRODH with proline (P-value  = 1.11x10-19), SLC16A9 with carnitine level (P-value  = 4.81x10-14) and uncovered a novel association between DMGDH and dimethyl-glycine (P-value  = 1.65x10-19) level.	Glycine	80-87	carbamoyl-phosphate synthase 1	Homo sapiens	70-74
19615365-1	2009	This study reports that the cysteine 22--&gt;glycine 22 substitution in the HIV-1 Tat 1-86 B significantly attenuates its neurotoxicity.	Glycine	45-52	tyrosine aminotransferase	Homo sapiens	82-85
26383032-2	2015	Transcripts encoding the kainate GRIK1 and AMPA GluA2 glutamate receptor subunits undergo editing that leads to a glycine/arginine (Q/R) exchange and reduced Ca(2+) permeability.	Glycine	114-121	glutamate receptor, ionotropic, kainate 1	Mus musculus	33-38
19757839-2	2009	The substitution of the His(4)-Pro(5) dipeptide sequence by the constrained Trp analogue Aia-Gly, in combination with beta(2)hVal substitution at the N-terminus, provided a new stable analogue H-(R)-beta(2)hVal-Tyr-Ile-Aia-Gly-Phe-OH (AL-40) that is a potent ligand for the Ang IV receptor IRAP and selective versus AP-N and the AT1 receptor.	Glycine	93-96	alanyl aminopeptidase, membrane	Homo sapiens	316-320
26383032-2	2015	Transcripts encoding the kainate GRIK1 and AMPA GluA2 glutamate receptor subunits undergo editing that leads to a glycine/arginine (Q/R) exchange and reduced Ca(2+) permeability.	Glycine	114-121	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	48-53
26241195-12	2015	Taken with previous results, these findings suggest that vGluT3 cells release glycine at some of their output synapses and glutamate at others.	Glycine	78-85	vesicular glutamate transporter 3	Papio anubis	57-63
19497974-2	2009	The long-acting analog h(Gly(2))GLP-2[1-33] is currently being tested for treatment of short bowel syndrome and Crohn"s disease.	Glycine	25-28	glucagon-like peptide 2 receptor	Mus musculus	32-37
19497974-5	2009	Chronic h(Gly(2))GLP-2[1-33] increased small intestinal weight/body weight (P &lt; 0.001), villus height (P &lt; 0.001), crypt depth (P &lt; 0.001), and crypt cell proliferation, as measured by expression of the proliferative marker Ki67 (P &lt; 0.05-0.01).	Glycine	10-13	glucagon-like peptide 2 receptor	Mus musculus	17-22
19497974-9	2009	Furthermore, mucin-depleted aberrant foci, consistent with progressive dysplasia, were almost exclusively present in h(Gly(2))GLP-2[1-33]-treated mice (P &lt; 0.01-0.001).	Glycine	117-122	glucagon-like peptide 2 receptor	Mus musculus	126-131
25331670-4	2014	The molecular docking study of T1R1 and T1R3 in complex with four peptides, including Lys-Gly-Asp-Glu-Ser-Leu-Leu-Ala, Ser-Glu-Glu, G1u-Ser, and Asp-Glu-Ser, displayed that the amino acid residue of SER146 and Glu277 in T1R3 may play great roles in the synergism of umami taste.	Glycine	90-93	taste 1 receptor member 1	Homo sapiens	31-35
19497974-10	2009	Additionally, adenocarcinomas developed in h(Gly(2))GLP-2[1-33]-treated mice but not in those receiving hGLP-2[3-33] or PBS.	Glycine	45-48	glucagon-like peptide 2 receptor	Mus musculus	52-57
19564338-7	2009	Mass spectrometric analysis revealed that ADAM10, but not ADAM9, cleaved PrP between Gly(228) and Arg(229), three residues away from the site of glycosylphosphatidylinositol anchor attachment.	Glycine	85-88	prion protein	Mus musculus	73-76
18533892-0	2008	Fusion of Epstein-Barr virus nuclear antigen-1-derived glycine-alanine repeat to trans-dominant HIV-1 Gag increases inhibitory activities and survival of transduced cells in vivo.	Glycine	55-62	Pr55(Gag)	Human immunodeficiency virus 1	102-105
18266927-1	2008	The neuronal glycine transporter GLYT2 is a plasma membrane protein that removes the neurotransmitter glycine from the synaptic cleft, thereby aiding the pre-synaptic terminal reloading and the termination of the glycinergic signal.	Glycine	13-20	solute carrier family 6 member 5	Homo sapiens	33-38
19722646-4	2009	Analytical ultracentrifugation and equilibrium disulfide interchange show that the stability of MS1 is greatest when Gly is at each "a" position of the heptad repeat (MS1-Gly), followed by Ala &gt; Val &gt; Ile.	Glycine	117-120	MS	Homo sapiens	96-99
25331670-4	2014	The molecular docking study of T1R1 and T1R3 in complex with four peptides, including Lys-Gly-Asp-Glu-Ser-Leu-Leu-Ala, Ser-Glu-Glu, G1u-Ser, and Asp-Glu-Ser, displayed that the amino acid residue of SER146 and Glu277 in T1R3 may play great roles in the synergism of umami taste.	Glycine	90-93	taste 1 receptor member 3	Homo sapiens	40-44
19722646-4	2009	Analytical ultracentrifugation and equilibrium disulfide interchange show that the stability of MS1 is greatest when Gly is at each "a" position of the heptad repeat (MS1-Gly), followed by Ala &gt; Val &gt; Ile.	Glycine	117-120	MS	Homo sapiens	167-170
19722646-4	2009	Analytical ultracentrifugation and equilibrium disulfide interchange show that the stability of MS1 is greatest when Gly is at each "a" position of the heptad repeat (MS1-Gly), followed by Ala &gt; Val &gt; Ile.	Glycine	171-174	MS	Homo sapiens	96-99
25375834-7	2014	Similarly, a natural substrate of MMP-2, Ace-Gln-Gly ~ Ile-Ala-Gly-Nme, can be converted to an inhibiting compound by two replacements, Ile by Cys and Gly by the d isomer of Cys, favoring formation of the zinc finger motif.	Glycine	49-52	matrix metallopeptidase 2	Homo sapiens	34-39
19722646-5	2009	Moreover, MS1-Gly has a strong tendency to form antiparallel dimers, MS1-Ala forms a mixture of parallel and antiparallel dimers, while MS1-Val and MS1-Ile have a preference to form parallel dimers.	Glycine	14-17	MS	Homo sapiens	10-13
19722646-8	2009	Finally, the electrostatic component arising from the partial charges of the backbones become significant in the antiparallel MS1-Gly and MS1-Ala conformations, due to close packing of the helices.	Glycine	130-133	MS	Homo sapiens	126-129
25375834-7	2014	Similarly, a natural substrate of MMP-2, Ace-Gln-Gly ~ Ile-Ala-Gly-Nme, can be converted to an inhibiting compound by two replacements, Ile by Cys and Gly by the d isomer of Cys, favoring formation of the zinc finger motif.	Glycine	63-66	matrix metallopeptidase 2	Homo sapiens	34-39
18475188-10	2008	RESULTS: Compared with vehicle controls, glycine-treated graft muscularis expressed a significant alleviation in mRNA peak expression for IL-6, IL-1beta, ICAM-1, MCP-1, TNFalpha, COX-2, and iNOS.	Glycine	41-48	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	179-184
25375834-7	2014	Similarly, a natural substrate of MMP-2, Ace-Gln-Gly ~ Ile-Ala-Gly-Nme, can be converted to an inhibiting compound by two replacements, Ile by Cys and Gly by the d isomer of Cys, favoring formation of the zinc finger motif.	Glycine	63-66	matrix metallopeptidase 2	Homo sapiens	34-39
25450364-3	2014	ALAS2 is a mitochondrial enzyme, which utilizes glycine and succinyl-CoA to form 5-aminolevulinic acid (ALA), a crucial precursor in heme synthesis.	Glycine	48-55	5'-aminolevulinate synthase 2	Homo sapiens	0-5
17998933-5	2008	Interestingly, the cleaved protein and mutant protein containing substitutions at glycines 15 and 17, two highly conserved amino acids in the N-terminal region, revealed a higher histone methyltransferase (HMTase) activity compared to the full-length protein.	Glycine	82-90	PR/SET domain 9	Homo sapiens	179-204
17998933-5	2008	Interestingly, the cleaved protein and mutant protein containing substitutions at glycines 15 and 17, two highly conserved amino acids in the N-terminal region, revealed a higher histone methyltransferase (HMTase) activity compared to the full-length protein.	Glycine	82-90	PR/SET domain 9	Homo sapiens	206-212
19549189-7	2009	The optimum pH of the SHMT reaction was 8.0 and an Arrhenius"s plot showed a transition temperature of 19 degrees C. Besides L-serine, PvSHMT forms an external aldimine complex with D-serine, L-alanine, L-threonine and glycine.	Glycine	219-226	serine hydroxymethyltransferase, cytosolic	Oryctolagus cuniculus	22-26
19583255-1	2009	It is demonstrated that sortase A (SrtA) can catalyze efficient coupling of peptides to GPI analogues with a glycine residue attached to the phosphoethanolamine moiety at the nonreducing end to form GPI-linked peptides.	Glycine	109-116	glucose-6-phosphate isomerase	Homo sapiens	199-202
25341953-4	2014	We mutated the constriction of water-selective rat AQP1 to mimic that of the ammonia-permeable human AQP8 by replacing Phenylalanine 56 with histidine, Histidine 180 with isoleucine, and Cysteine 189 with glycine, alone and in combination.	Glycine	205-212	aquaporin 1	Rattus norvegicus	51-55
19584562-2	2009	Alignment of deduced amino acid sequences of SLC10 family members and homologous genes in various species revealed a highly conserved region that corresponds to Gly(104)-Pro(142) of SLC10A2.	Glycine	161-164	solute carrier family 10, member 2	Mus musculus	182-189
17959260-1	2008	Low dose of D-cycloserine (DCS), a partial agonist of glycine binding site on N-methyl-D-aspartate (NMDA) receptors, can facilitate extracellular signal-regulated kinase1/2 (ERK1/2) activity in the amygdala and modulate emotional behavior.	Glycine	54-61	mitogen activated protein kinase 3	Rattus norvegicus	132-172
17959260-1	2008	Low dose of D-cycloserine (DCS), a partial agonist of glycine binding site on N-methyl-D-aspartate (NMDA) receptors, can facilitate extracellular signal-regulated kinase1/2 (ERK1/2) activity in the amygdala and modulate emotional behavior.	Glycine	54-61	mitogen activated protein kinase 3	Rattus norvegicus	174-180
18029081-1	2008	The N-terminal glycine of the A-chain in insulin is reported to be one of the residues that binds to the insulin receptor.	Glycine	15-22	insulin receptor	Homo sapiens	105-121
25178856-7	2014	Further, the significant inhibition of the uptake of Gly-Sar by TRH analogs confirmed the PepT1-mediated transport mechanism.	Glycine	53-56	thyrotropin releasing hormone	Homo sapiens	64-67
25205466-5	2014	The SNP rs10774671 affects splicing to one of the exons in the OAS1 gene giving rise to differential expression of the OAS1 isoforms, and the SNP rs1131454 (former rs3741981) resides in exon 3 giving rise to OAS1 isoforms with either a Glycine or a Serine at position 162 in the core OAS unit.	Glycine	236-243	2'-5'-oligoadenylate synthetase 1	Homo sapiens	63-67
19536304-10	2009	Leucine, phenylalanine, and glycine are conserved at the 24th, 190th, and 329th position in the CYP1B1 protein in different species, suggestive of important functions at these loci.	Glycine	28-35	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	96-102
24973220-5	2014	Pulse dipolar EPR spectroscopy provides evidence that purified full-length Syt1 is oligomerized in the membrane, and mutagenesis indicates that a glycine zipper/GXXXG motif within the linker helps mediate oligomerization.	Glycine	146-153	synaptotagmin 1	Homo sapiens	75-79
19528482-4	2009	As expected, these enhancements were markedly suppressed with the addition of anti-alphavbeta3 antibody or arginine-glycine-aspartic acid serine (RGDS) peptide to the medium.	Glycine	116-123	ral guanine nucleotide dissociation stimulator	Homo sapiens	146-150
24682789-4	2014	Here, we identified two essential sites located on the Nt of Aurora-A (Lys 99 and Lys 119) and demonstrate that mutation of either residue to Gly could cause the Nt and C-terminal lobes of the catalytic domain in Aurora-A to form a closed conformation, resulting in a loss of kinase activity.	Glycine	142-145	aurora kinase A	Homo sapiens	61-69
19289494-3	2009	Using the Cre/lox-conditional system, we show that the loss of PRMT1 in mouse embryonic fibroblasts (MEFs) leads to the loss of arginine methylation of substrates harboring a glycine-arginine rich motif, including Sam68 and MRE11.	Glycine	175-182	lysyl oxidase	Mus musculus	14-17
24682789-4	2014	Here, we identified two essential sites located on the Nt of Aurora-A (Lys 99 and Lys 119) and demonstrate that mutation of either residue to Gly could cause the Nt and C-terminal lobes of the catalytic domain in Aurora-A to form a closed conformation, resulting in a loss of kinase activity.	Glycine	142-145	aurora kinase A	Homo sapiens	213-221
24935095-8	2014	The identified Cg25C mutants display weaker and largely temperature-sensitive phenotypes that result from glycine substitutions in different Gly-X-Y repeats of the triple helix-forming domain.	Glycine	106-113	Collagen type IV alpha 1	Drosophila melanogaster	15-20
19272411-3	2009	METHODS: Static and dynamic light scattering, circular dichroism, co-purification and enzyme assays are used to investigate the role of a glycine conserved in all Pdx1 family members.	Glycine	138-145	pancreatic and duodenal homeobox 1	Homo sapiens	163-167
19272411-7	2009	CONCLUSIONS: As the mutated glycine occupies an unrestricted region of the Ramachandran plot the additional stereo-chemical restrictions imposed on alanine residues strongly support our hypothesis that significant structural rearrangement of Pdx1 is required during the transition from hexamer to dodecamer.	Glycine	28-35	pancreatic and duodenal homeobox 1	Homo sapiens	242-246
24935095-8	2014	The identified Cg25C mutants display weaker and largely temperature-sensitive phenotypes that result from glycine substitutions in different Gly-X-Y repeats of the triple helix-forming domain.	Glycine	141-144	Collagen type IV alpha 1	Drosophila melanogaster	15-20
19154202-2	2009	AS2 encodes a plant-specific protein with an AS2/LATERAL ORGAN BOUNDARIES (AS2/LOB) domain that includes a cysteine repeat, a conserved single glycine residue and a leucine-zipper-like sequence in its amino-terminal half.	Glycine	143-150	Lateral organ boundaries (LOB) domain family protein	Arabidopsis thaliana	0-3
19154202-2	2009	AS2 encodes a plant-specific protein with an AS2/LATERAL ORGAN BOUNDARIES (AS2/LOB) domain that includes a cysteine repeat, a conserved single glycine residue and a leucine-zipper-like sequence in its amino-terminal half.	Glycine	143-150	Lateral organ boundaries (LOB) domain family protein	Arabidopsis thaliana	45-48
24710069-7	2014	Modeling suggests that the two hydrogen bonds between the highly conserved residues Ser-528 and glycine-525 are required for PDRP-mediated phosphorylation of the active-site Thr-527 of PPDK.	Glycine	96-103	pyruvate, phosphate dikinase 1, chloroplastic	Zea mays	185-189
19154202-2	2009	AS2 encodes a plant-specific protein with an AS2/LATERAL ORGAN BOUNDARIES (AS2/LOB) domain that includes a cysteine repeat, a conserved single glycine residue and a leucine-zipper-like sequence in its amino-terminal half.	Glycine	143-150	Lateral organ boundaries (LOB) domain family protein	Arabidopsis thaliana	49-73
19154202-2	2009	AS2 encodes a plant-specific protein with an AS2/LATERAL ORGAN BOUNDARIES (AS2/LOB) domain that includes a cysteine repeat, a conserved single glycine residue and a leucine-zipper-like sequence in its amino-terminal half.	Glycine	143-150	Lateral organ boundaries (LOB) domain family protein	Arabidopsis thaliana	45-48
24368416-2	2014	GlyRS charges the amino acid glycine with its cognate tRNA and is therefore essential for protein translation.	Glycine	29-36	glycyl-tRNA synthetase	Mus musculus	0-5
19153190-0	2009	Glycine-extended gastrin inhibits apoptosis in Barrett"s oesophageal and oesophageal adenocarcinoma cells through JAK2/STAT3 activation.	Glycine	0-7	Janus kinase 2	Homo sapiens	114-118
24576660-2	2014	GLYAT catalyzes the formation of hippurate (N-benzoylglycine) from the corresponding glycine and benzoyl-CoA.	Glycine	53-60	glycine-N-acyltransferase	Mus musculus	0-5
19155213-1	2009	Human liver peroxisomal alanine:glyoxylate aminotransferase (AGT) is a pyridoxal 5"-phosphate (PLP)-dependent enzyme that converts glyoxylate into glycine.	Glycine	147-154	pyridoxal phosphatase	Homo sapiens	95-98
19621799-4	2009	Also, enkephalins, VIP and SS are able to stimulate or suppress the inhibitory effect of GABA and glycine.	Glycine	98-105	somatostatin	Felis catus	27-29
24576660-7	2014	The steady-state kinetic constants determined for recombinant mGLYAT for the substrates benzoyl-CoA and glycine, were shown to be consistent with other reported species (rat, human, bovine, ovine, and rhesus monkey).	Glycine	104-111	glycine-N-acyltransferase	Mus musculus	62-68
24576660-8	2014	The successful recombinant expression and purification of mGLYAT can lead to solve unanswered questions associated with this enzyme, consisting of what is the chemical mechanism and what catalytic residues are essential for the how this phase II metabolic detoxification enzyme conjugates glycine to xenobiotic and endogenous carboxylic acids.	Glycine	289-296	glycine-N-acyltransferase	Mus musculus	58-64
19017728-2	2009	Creatine synthesis requires three amino acids, methionine, glycine, and arginine, and two enzymes, l-arginine:glycine amidinotransferase (AGAT), which produces guanidinoacetate acid (GAA), and guanidinoacetate methyltransferase (GAMT), which methylates GAA to produce creatine.	Glycine	59-66	glycine amidinotransferase	Rattus norvegicus	99-136
24352465-9	2014	Given that these mutations lie next to the glycine-rich region of PrP that can abrogate prion infection, these findings provide further support for small, protease-sensitive prion species having a significant role in the progression of prion disease and that the hydrophobic domain is an important determinant of PrP conversion.	Glycine	43-50	prion protein	Mus musculus	66-69
19017728-2	2009	Creatine synthesis requires three amino acids, methionine, glycine, and arginine, and two enzymes, l-arginine:glycine amidinotransferase (AGAT), which produces guanidinoacetate acid (GAA), and guanidinoacetate methyltransferase (GAMT), which methylates GAA to produce creatine.	Glycine	59-66	glycine amidinotransferase	Rattus norvegicus	138-142
24467211-6	2014	This study defines the role of H-protein in GLDC-catalyzed glycine decarboxylation.	Glycine	59-66	glycine decarboxylase	Homo sapiens	44-48
19217525-3	2009	METHODS: A gal-3 binding peptide, ANTPCGPYTHDCPVKR, was synthesized with a Gly-Ser-Gly (GSG) spacer and 1,4,7,10-tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid (DOTA) and then radiolabeled with (111)In.	Glycine	75-78	galectin 3	Homo sapiens	11-16
24446171-4	2014	Mice homozygous for the null mutation in Dtnbp1 exhibited significantly reduced NMDAR-dependent synaptic potentiation compared to wild type mice, an effect that could be rescued by bath application of the NMDA receptor coagonist glycine (10 muM).	Glycine	229-236	dystrobrevin binding protein 1	Mus musculus	41-47
18987357-2	2009	Using chimeric human-rat alphaIIbbeta3 molecules, we found that this difference in Arg-Gly-Asp-Ser (RGDS) sensitivity was the result of amino acid substitutions at residues 157, 159, and 162 in the W3:4-1 loop and an Asp-His replacement at residue 232 in the W4:4-1 loop of the alphaIIb beta propeller.	Glycine	87-90	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	100-104
19028686-10	2009	These studies suggest that cathepsin K interaction with type I collagen is required for 1) the release of cryptic Arg-Gly-Asp motifs during the initial attachment of osteoclasts and 2) termination of resorption via the creation of autocrine signals originating from type I collagen degradation.	Glycine	118-121	cathepsin K	Mus musculus	27-38
24516781-10	2014	Anandamide (230%) and N-arachidonoyl tyrosine (170%) substantially activated hTRPA1 at 30 muM, however, N-arachidonoyl conjugates of glycine and taurine were less effective while N-acyl conjugates of 5-HT did not affect hTRPA1.	Glycine	133-140	transient receptor potential cation channel subfamily A member 1	Homo sapiens	77-83
19116148-2	2009	DNA sequencing revealed that these cells expressed an equilibrative nucleoside transporter 1 (ENT1) with a single missense mutation resulting in glycine to arginine replacement (G24R).	Glycine	145-152	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	54-92
19116148-2	2009	DNA sequencing revealed that these cells expressed an equilibrative nucleoside transporter 1 (ENT1) with a single missense mutation resulting in glycine to arginine replacement (G24R).	Glycine	145-152	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	94-98
20066896-1	2009	The genotype analysis of the Gly and Arg allele at codon 388 of fibroblast growth factor receptor-4 (FGFR4) gene was evaluated using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in a hospital-based Malaysian population.	Glycine	29-32	fibroblast growth factor receptor 4	Homo sapiens	64-99
24516781-10	2014	Anandamide (230%) and N-arachidonoyl tyrosine (170%) substantially activated hTRPA1 at 30 muM, however, N-arachidonoyl conjugates of glycine and taurine were less effective while N-acyl conjugates of 5-HT did not affect hTRPA1.	Glycine	133-140	transient receptor potential cation channel subfamily A member 1	Homo sapiens	220-226
20066896-1	2009	The genotype analysis of the Gly and Arg allele at codon 388 of fibroblast growth factor receptor-4 (FGFR4) gene was evaluated using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in a hospital-based Malaysian population.	Glycine	29-32	fibroblast growth factor receptor 4	Homo sapiens	101-106
24466299-2	2014	A previous study showed that the substitution of +20A&gt;G in PPARG changed the 7(th) amino acid from Asp to Gly, creating a mutant referred to as PPARG Asp7Gly.	Glycine	109-112	peroxisome proliferator activated receptor gamma	Bos taurus	62-67
24466299-2	2014	A previous study showed that the substitution of +20A&gt;G in PPARG changed the 7(th) amino acid from Asp to Gly, creating a mutant referred to as PPARG Asp7Gly.	Glycine	109-112	peroxisome proliferator activated receptor gamma	Bos taurus	147-152
24076356-8	2014	When comparing the myoglobin sequence from TA with the Ovis aries myoglobin sequence, variations were observed at codons 21 (GGT GAT) and 78 (GAA AAG), and these variations lead to changes in the corresponding amino acids, i.e., Gly Asp and Glu Lys, respectively.	Glycine	229-232	myoglobin	Ovis aries	66-75
24140612-6	2014	While osteoclast activation occurred when pASP was used as the process-directing agent, using OPN resulted in a dramatic effect on osteoclast activation, presumably because of the inherent arginine-glycine-aspartate acid ligands of OPN.	Glycine	198-205	secreted phosphoprotein 1	Mus musculus	94-97
25309911-4	2014	A virtual glycine scan revealed the contributions of individual residues to the energy of binding of 1-methylenesulfamide-1,2-dicarba-closo-dodecaborane to CAII and CAIX, respectively.	Glycine	10-17	carbonic anhydrase 9	Homo sapiens	165-169
24028418-2	2014	Using an explicit solvent all atomic MD simulation, we explored the stability, conformational dynamics and association force of different single-layer models of the full-length wild-type and glycine mutants of amylin (pentamer) obtained from a recent high resolution fibril model.	Glycine	191-198	islet amyloid polypeptide	Homo sapiens	210-216
24191046-2	2013	A central constriction of six apolar residues has been shown to form a seal, but also to determine the hydrophobicity threshold for membrane integration: Mutation of these residues in yeast Sec61p to glycines, serines, aspartates, or lysines lowered the hydrophobicity required for integration; mutation to alanines increased it.	Glycine	200-208	translocon subunit SEC61	Saccharomyces cerevisiae S288C	190-196
24072709-0	2013	Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	121-126
24072709-2	2013	They are tetrameric complexes composed of glycine-binding GluN1 and GluN3 subunits together with glutamate-binding GluN2 subunits.	Glycine	42-49	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	58-63
24072709-3	2013	Subunit-selective antagonists that discriminate between the glycine sites of GluN1 and GluN3 subunits would be valuable pharmacological tools for studies on the function and physiological roles of NMDA receptor subtypes.	Glycine	60-67	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	77-82
24072709-4	2013	In a virtual screening for antagonists that exploit differences in the orthosteric binding site of GluN1 and GluN3 subunits, we identified a novel glycine site antagonist, 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one (TK40).	Glycine	147-154	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	99-104
24072709-5	2013	Here, we show by Schild analysis that TK40 is a potent competitive antagonist with Kb values of 21-63 nM at the GluN1 glycine-binding site of the four recombinant GluN1/N2A-D receptors.	Glycine	118-125	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	112-117
24072709-5	2013	Here, we show by Schild analysis that TK40 is a potent competitive antagonist with Kb values of 21-63 nM at the GluN1 glycine-binding site of the four recombinant GluN1/N2A-D receptors.	Glycine	118-125	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	163-168
24072709-7	2013	Binding experiments on rat brain membranes and the purified GluN1 ligand-binding domain using glycine site GluN1 radioligands further confirmed the competitive interaction and high potency.	Glycine	94-101	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	60-65
24072709-7	2013	Binding experiments on rat brain membranes and the purified GluN1 ligand-binding domain using glycine site GluN1 radioligands further confirmed the competitive interaction and high potency.	Glycine	94-101	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	107-112
24225653-2	2013	We have isolated the recessive medaka mutation tintachina (tch), which carries an inactivating modification of the conserved glycine residue (G75R) of the proton pump subunit atp6v1Ba/vatB1.	Glycine	125-132	V-type proton ATPase subunit B, kidney isoform	Oryzias latipes	175-183
24250787-2	2013	There are two common naturally occurring polymorphisms within the human beta1-adrenoceptor sequence: Ser or Gly at position 49 in the N-terminus and Gly or Arg at position 389 in the C-terminus and some clinical studies have suggested that expression of certain variants may be associated with disease and affect response to treatment with beta-blockers.	Glycine	108-111	adrenoceptor beta 1	Homo sapiens	72-90
17657484-3	2008	However, in the inwardly rectifying (Kir) potassium channel family, the role of this "hinge" residue in the second transmembrane domain (TM2) and that of another putative glycine gating hinge at the base of TM2 remain controversial.	Glycine	171-178	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	37-40
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	232-239	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	51-54
24250787-2	2013	There are two common naturally occurring polymorphisms within the human beta1-adrenoceptor sequence: Ser or Gly at position 49 in the N-terminus and Gly or Arg at position 389 in the C-terminus and some clinical studies have suggested that expression of certain variants may be associated with disease and affect response to treatment with beta-blockers.	Glycine	149-152	adrenoceptor beta 1	Homo sapiens	72-90
23992455-0	2013	ATP binding to human serine racemase is cooperative and modulated by glycine.	Glycine	69-76	serine racemase	Homo sapiens	21-36
23992455-6	2013	Glycine, an active-site ligand, increased the serine racemase affinity for ATP by ~ 22-fold, abolishing cooperativity.	Glycine	0-7	serine racemase	Homo sapiens	46-61
24121337-4	2013	Interestingly, the Gly-rich loop of CDK2 formed a beta-sheet that was different from that of MK2.	Glycine	19-22	cyclin dependent kinase 2	Homo sapiens	36-40
17845003-2	2008	Both integrins and APN recognize a broad range of peptides containing RGD (Arg-Gly-Asp) and NGR (Asn-Gly-Arg) motifs, respectively.	Glycine	79-82	alanyl aminopeptidase, membrane	Homo sapiens	19-22
23856421-4	2013	Carbohydrate deficient transferrin testing showed a pattern pointing to a CDG type I. Sanger sequencing of DPM1 (dolichol-P-mannose synthase subunit 1) revealed a novel Gly &gt; Val change c.455G &gt; T missense mutation resulting in p.Gly152Val) of unknown pathogenicity and deletion/duplication analysis revealed an intragenic deletion from exons 3 to 7 on the other allele.	Glycine	169-172	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	107-111
24144057-6	2013	Furthermore, there was a 20% reduction in SOD-specific activity in the glycine-treated group, which correlated with SOD2 expression.	Glycine	71-78	superoxide dismutase 2	Homo sapiens	42-45
20641798-8	2004	alpha-MSH (Ac-Ser(1)-Tyr(2)-Ser(3)-Met(4)-Glu(5)-His(6)-Phe(7)-Arg(8)-Trp(9)-Gly(10)-Lys(11)-Pro(12)-Val(13)-NH2), composed of 13 amino acids, is the most potent naturally occurring melanotropic peptide (5).	Glycine	77-80	pro-opiomelanocortin-alpha	Mus musculus	0-9
24144057-6	2013	Furthermore, there was a 20% reduction in SOD-specific activity in the glycine-treated group, which correlated with SOD2 expression.	Glycine	71-78	superoxide dismutase 2	Homo sapiens	116-120
23872361-3	2013	In the present study we examined the expression of p62 in the mouse lens and compared its expression in wild-type lenses with that in lenses from knock-in mice with an arginine to glycine mutation in alphaB-crystallin (alphaB-R120G) that is known to cause human hereditary cataract.	Glycine	180-187	crystallin, alpha B	Mus musculus	200-217
18004849-1	2007	A recently developed extended Lagrangian model employing localized basis functions and nonperiodic boundary conditions (GLOB/ADMP) was applied to the radicals issuing from the homolytic breaking of the C(alpha)-H(alpha) bond of glycine in aqueous solution at different pH values.	Glycine	228-235	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)	Homo sapiens	120-124
18845259-1	2009	Dihydrolipoamide dehydrogenase (LADH) is a FAD-linked subunit of alpha-ketoglutarate, pyruvate and branched-chain amino acid dehydrogenases and the glycine cleavage system.	Glycine	148-155	dihydrolipoamide dehydrogenase	Homo sapiens	0-30
17998393-8	2007	Because NE recognition of substrates occurs with a preference for binding valines at the active site, several valines in the extracellular loops of alpha and gamma ENaC were sequentially substituted with glycines.	Glycine	204-212	elastase, neutrophil expressed	Homo sapiens	8-10
23800848-3	2013	One mouse model encodes an FHC-associated mutation in alpha-tropomyosin: Glu   Gly at amino acid 180, designated as Tm180.	Glycine	79-82	tropomyosin 1, alpha	Mus musculus	54-71
19140841-2	2009	MICA*054 has a nucleotide substitution of A to G at position 871 (codon 268), encoding an amino acid change of serine to glycine in the alpha-3 domain.	Glycine	121-128	MHC class I polypeptide-related sequence A	Homo sapiens	0-4
19026641-6	2008	The double-glycine motif, which is conserved in the Arf family, only occurs in Rab28 and Rab7B of the Rab family, and may have a profound effect on their catalytic activities.	Glycine	11-18	RAB7B, member RAS oncogene family	Homo sapiens	89-94
18805436-5	2008	Endogenous glycine and D-serine both act as co-agonists on the strychnine-insensitive GlyB site on the NMDA receptor, and along with glutamate, co-activate the NMDA receptor.	Glycine	11-18	Glycine auxotroph B, complementation of hamster	Homo sapiens	86-90
18008022-0	2007	Amino acids that confer transport of raffinose and maltose sugars in the raffinose permease (RafB) of Escherichia coli as implicated by spontaneous mutations at Val-35, Ser-138, Ser-139, Gly-389 and Ile-391.	Glycine	187-190	hypothetical protein	Escherichia coli	93-97
18805436-6	2008	Forebrain synaptic glycine and d-serine levels are regulated by the Glycine Transporter-1 (GlyT1) and the arginine-serine-cysteine transporter-1 (Asc-1), respectively; in addition to D-serine metabolism by D-Amino Acid Oxidase (DAAO).	Glycine	19-26	solute carrier family 7 member 10	Homo sapiens	106-144
23922881-9	2013	Mechanistically, overexpression of PIMT or GSPB2 increased the phosphorylation of ERK1/2 and GSK3beta in the gly-LDL induced VEC.	Glycine	109-112	mitogen activated protein kinase 3	Rattus norvegicus	82-88
18805436-6	2008	Forebrain synaptic glycine and d-serine levels are regulated by the Glycine Transporter-1 (GlyT1) and the arginine-serine-cysteine transporter-1 (Asc-1), respectively; in addition to D-serine metabolism by D-Amino Acid Oxidase (DAAO).	Glycine	19-26	solute carrier family 7 member 10	Homo sapiens	146-151
18805436-7	2008	Together, these processes prevent the GlyB site from being saturated by the high extracellular levels of brain glycine, and perhaps d-serine, in vivo.	Glycine	111-118	Glycine auxotroph B, complementation of hamster	Homo sapiens	38-42
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	solute carrier family 7 member 10	Homo sapiens	118-123
23922881-9	2013	Mechanistically, overexpression of PIMT or GSPB2 increased the phosphorylation of ERK1/2 and GSK3beta in the gly-LDL induced VEC.	Glycine	109-112	glycogen synthase kinase 3 beta	Rattus norvegicus	93-101
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	Glycine auxotroph B, complementation of hamster	Homo sapiens	270-274
17671992-8	2007	Finally, the HIV-1 protein gp120 potently mimicked the NMDA co-agonists glycine and D-serine, being significantly effective at 30 pM.	Glycine	72-79	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	27-32
17878266-7	2007	Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	48-52
17878266-7	2007	Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	127-131
23689818-6	2013	Using chimeric and point mutated variants of TT2 and PAP4 we found that exchange of a single amino acid, Gly/Arg(39) in the R2 domain combined with an exchange of a four amino acid motif in the R3 domain, could swap the pathway selection of TT2 and PAP4, thereby converting in planta specificity of the PA towards the anthocyanin pathway and vice versa.	Glycine	105-108	Duplicated homeodomain-like superfamily protein	Arabidopsis thaliana	45-48
18501442-0	2008	A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36).	Glycine	57-60	peptide YY	Canis lupus familiaris	25-28
18501442-0	2008	A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36).	Glycine	57-60	peptide YY	Canis lupus familiaris	70-73
18501442-4	2008	This analysis confirmed the identity of a new form of PYY, PYY(1-36)-Gly, which co-elutes with PYY(1-36)-NH(2) through all three of separation steps used.	Glycine	69-72	peptide YY	Canis lupus familiaris	54-57
18501442-4	2008	This analysis confirmed the identity of a new form of PYY, PYY(1-36)-Gly, which co-elutes with PYY(1-36)-NH(2) through all three of separation steps used.	Glycine	69-72	peptide YY	Canis lupus familiaris	59-62
18501442-4	2008	This analysis confirmed the identity of a new form of PYY, PYY(1-36)-Gly, which co-elutes with PYY(1-36)-NH(2) through all three of separation steps used.	Glycine	69-72	peptide YY	Canis lupus familiaris	59-62
18501442-5	2008	The PYY(1-36)-Gly form represents approximately 20% of the total PYY found in this region of the canine intestine.	Glycine	14-17	peptide YY	Canis lupus familiaris	4-7
23874158-6	2013	p150(Glued) alters microtubule dynamics by binding both to microtubules and to tubulin dimers; both the N-terminal CAP-Gly and basic domains of p150(Glued) are required in tandem for this activity.	Glycine	119-122	chromatin assembly factor 1 subunit A	Homo sapiens	0-4
18501442-5	2008	The PYY(1-36)-Gly form represents approximately 20% of the total PYY found in this region of the canine intestine.	Glycine	14-17	peptide YY	Canis lupus familiaris	65-68
18501442-7	2008	The physiological implication of the Gly-extended form of PYY(1-36) warrants further investigation.	Glycine	37-40	peptide YY	Canis lupus familiaris	58-61
17917276-3	2007	Similarly, Rb(1) was changed into 20(S)-Rg(3), 20(R)-Rg(3), Rk(1), and Rg(5) when it was heat-processed with the same amount of glycine, but the generated amount of 20(S)-Rg(3) was higher than when Rb(1) was heat-processed without amino acids, and a significant increase in Maillard reaction products (MRPs) was noted.	Glycine	128-135	RB transcriptional corepressor 1	Homo sapiens	11-16
17714089-14	2007	There are two common polymorphic locations of the beta(1)-adrenoceptor, at amino acids 49 (Ser/Gly) and 389 (Arg/Gly).	Glycine	95-98	adrenoceptor beta 1	Homo sapiens	50-70
23874158-6	2013	p150(Glued) alters microtubule dynamics by binding both to microtubules and to tubulin dimers; both the N-terminal CAP-Gly and basic domains of p150(Glued) are required in tandem for this activity.	Glycine	119-122	chromatin assembly factor 1 subunit A	Homo sapiens	144-148
17714089-14	2007	There are two common polymorphic locations of the beta(1)-adrenoceptor, at amino acids 49 (Ser/Gly) and 389 (Arg/Gly).	Glycine	113-116	adrenoceptor beta 1	Homo sapiens	50-70
19036977-1	2008	RNA editing that converts adenosine to inosine replaces the gene-encoded Ile, Asn, and Ile (INI) of serotonin [5-hydroxytryptamine (5-HT)] receptor 2C (5-HT(2C)R) with Val, Gly, and Val (VGV).	Glycine	173-176	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	152-161
23379364-3	2013	We investigated the association between a single nucleotide polymorphism in the TRIM5alpha linker 2 region (rs11038628), which substituted aspartic acid (D) for glycine (G) at position 249, with susceptibility to HIV-1 infection in Japanese and Indian subjects.	Glycine	161-168	tripartite motif containing 5	Homo sapiens	80-90
20641607-4	2004	Neuromedin B (NMB) is a peptide of 32 amino acids from porcine spinal cords with Gly-His-Phe-Met at its C-terminus.	Glycine	81-84	neuromedin B	Homo sapiens	0-12
20641607-4	2004	Neuromedin B (NMB) is a peptide of 32 amino acids from porcine spinal cords with Gly-His-Phe-Met at its C-terminus.	Glycine	81-84	neuromedin B	Homo sapiens	14-17
17660250-9	2007	Interestingly, the Gly mutant has a Ki of 2.1 nM for MMP-9 and &gt;40 muM for MMP-2, indicating that engineered TIMPs can discriminate between MMPs in the same subfamily.	Glycine	19-22	matrix metallopeptidase 2	Homo sapiens	78-83
17660250-9	2007	Interestingly, the Gly mutant has a Ki of 2.1 nM for MMP-9 and &gt;40 muM for MMP-2, indicating that engineered TIMPs can discriminate between MMPs in the same subfamily.	Glycine	19-22	matrix metallopeptidase 2	Homo sapiens	143-147
23588958-10	2013	We concluded that the Gly allele of ADRB1 Arg389Gly polymorphism might confer lower risk for EH, especially in East Asians.	Glycine	22-25	adrenoceptor beta 1	Homo sapiens	36-41
17672455-4	2007	The template sequence was based on the alpha1(V)436-450 collagen region, which is hydrolyzed at the Gly(439)-Val(440) bond selectively by MMP-2 and MMP-9.	Glycine	100-103	matrix metallopeptidase 2	Homo sapiens	138-143
17503466-3	2007	The predicated NBS of murine VDAC1 (mVDAC1) was mutated by replacing two glycine residues with alanines or a conserved lysine residue with a serine.	Glycine	73-80	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	15-18
18815228-0	2008	Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix.	Glycine	122-125	prostaglandin E receptor 3 (subtype EP3)	Mus musculus	18-21
23609608-5	2013	AtCPK5 was a substrate for plant N-myristoyltransferase and myristoylation was prevented by converting the glycine at the proposed site of myristate attachment to alanine (G2A).	Glycine	107-114	calmodulin-domain protein kinase 5	Arabidopsis thaliana	0-6
18534744-4	2008	mBAFF (a soluble BAFF mutant with amino acid 217-224 being replaced by two glycine residues) may be used as a competitive inhibitor for BAFF to treat relevant malignant hematologic diseases.	Glycine	75-82	tumor necrosis factor (ligand) superfamily, member 13b	Mus musculus	0-5
18534744-4	2008	mBAFF (a soluble BAFF mutant with amino acid 217-224 being replaced by two glycine residues) may be used as a competitive inhibitor for BAFF to treat relevant malignant hematologic diseases.	Glycine	75-82	TNF superfamily member 13b	Homo sapiens	1-5
18534744-4	2008	mBAFF (a soluble BAFF mutant with amino acid 217-224 being replaced by two glycine residues) may be used as a competitive inhibitor for BAFF to treat relevant malignant hematologic diseases.	Glycine	75-82	TNF superfamily member 13b	Homo sapiens	17-21
17502428-0	2007	Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.	Glycine	36-43	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	120-123
17585213-12	2007	However, carriers of at least one Gly allele of the beta1-adrenergic receptor polymorphism Arg389Gly showed a higher number of adverse events than Arg homozygous (32.4% vs. 18.7%; hazard ratio, 1.87; 95% confidence interval, 1.04-3.35; P = 0.04).	Glycine	34-37	adrenoceptor beta 1	Homo sapiens	52-77
28516014-7	2013	We designed this approach and then validated its efficacy using a 24 amino acid minimum binding region of the intrinsically disordered, neuron-specific substrates, Neurogranin and Neuromodulin, joined via a Gly-linker to their interacting partner, Calmodulin.	Glycine	207-210	neurogranin	Homo sapiens	164-175
17546040-4	2007	Biochemical analyses showed that Dyn2 binds to a linear motif (termed DID(Nup159)) inserted between the Phe-Gly repeat and coiled-coil domain of Nup159.	Glycine	108-111	dynein light chain	Saccharomyces cerevisiae S288C	33-37
17546040-6	2007	These findings imply that the rigid 20 nm long Dyn2-DID(Nup159) filament projects the Nup159 Phe-Gly repeats from the Nup82 module.	Glycine	97-100	dynein light chain	Saccharomyces cerevisiae S288C	47-51
17511476-11	2007	Substitution of RGS7 Glu-73 and Asp-74 for the corresponding Ser and Gly residues (ED/SG mutation) of RGS9 diminished the DEP-Gbeta5 interaction.	Glycine	69-72	regulator of G protein signaling 7	Homo sapiens	16-20
18636091-2	2008	Using ligand binding assays, crystallographic analysis, and all atom MD simulations, we investigate mechanisms underlying the binding by NR3A and NR3B of glycine and D-serine, which are candidate neurotransmitters for NMDA receptors containing NR3 subunits.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	137-140
18670643-2	2008	A common polymorphism of FGFR-4 in which arginine (Arg(388)) replaces glycine (Gly(388)) at amino acid 388 is associated with progression in human prostate cancer.	Glycine	70-77	fibroblast growth factor receptor 4	Homo sapiens	25-31
23237322-10	2013	We suggest that L383 and the flanking glycine residues form a spatial arrangement in PS1 that is critical for docking and/or cleavage of different gamma-secretase substrates.	Glycine	38-45	presenilin 1	Homo sapiens	85-88
18670643-2	2008	A common polymorphism of FGFR-4 in which arginine (Arg(388)) replaces glycine (Gly(388)) at amino acid 388 is associated with progression in human prostate cancer.	Glycine	79-82	fibroblast growth factor receptor 4	Homo sapiens	25-31
18670643-4	2008	In patients bearing the FGFR-4 Gly(388) variant, expression of Huntingtin-interacting protein 1 (HIP1), which occurs in more than half of human prostate cancers, also results in FGFR-4 stabilization.	Glycine	31-34	fibroblast growth factor receptor 4	Homo sapiens	24-30
18670643-4	2008	In patients bearing the FGFR-4 Gly(388) variant, expression of Huntingtin-interacting protein 1 (HIP1), which occurs in more than half of human prostate cancers, also results in FGFR-4 stabilization.	Glycine	31-34	fibroblast growth factor receptor 4	Homo sapiens	178-184
17512307-5	2007	Among whites, the ADRB1 Arg389--&gt;Gly variant associated with insulin concentrations and HOMA(IR): mean +/- SD values for insulin and HOMA(IR) in Arg389 homozygotes and carriers of the Gly were 10 +/- 7.0 and 12 +/- 9.4 micro IU/mL (P = .02) and 2.1 +/- 1.7 and 2.6 +/- 2.2 (P = .057), respectively.	Glycine	36-39	adrenoceptor beta 1	Homo sapiens	18-23
17512307-5	2007	Among whites, the ADRB1 Arg389--&gt;Gly variant associated with insulin concentrations and HOMA(IR): mean +/- SD values for insulin and HOMA(IR) in Arg389 homozygotes and carriers of the Gly were 10 +/- 7.0 and 12 +/- 9.4 micro IU/mL (P = .02) and 2.1 +/- 1.7 and 2.6 +/- 2.2 (P = .057), respectively.	Glycine	187-190	adrenoceptor beta 1	Homo sapiens	18-23
23325127-5	2013	The base substitutions change a glycine to arginine in the fibronectin type 3 domain of nephrin and a proline to arginine in a conserved proline-rich region in Neph3.	Glycine	32-39	NPHS1 adhesion molecule, nephrin	Canis lupus familiaris	88-95
17445548-7	2007	After the glycine dose, the C(8) plus C(5) positions were enriched, whereas no significant enrichment at C(2) was found.	Glycine	10-17	homeobox C8	Homo sapiens	28-32
17445548-9	2007	To our knowledge, this is the first study to investigate (13)C enrichment from formate and glycine independently into the C(2) and C(8) positions of purine in the same subjects.	Glycine	91-98	homeobox C8	Homo sapiens	131-135
23419876-0	2013	New findings concerning vertebrate porin II--on the relevance of glycine motifs of type-1 VDAC.	Glycine	65-72	voltage dependent anion channel 1	Homo sapiens	35-40
17300128-2	2007	beta-D-Galactopyranoside, the substrate of beta-galactosidase, was conjugated to 2SBPO through a para-substituted benzyloxycarbonyl group and a glycine residue, which serve as a self-immolative spacer and as a molecular blocker to mask the optical signal of 2SBPO, respectively.	Glycine	144-151	galactosidase beta 1	Homo sapiens	43-61
17338550-7	2007	Differences in specificity between secreted and membrane-type (MT) MMPs were also observed for both sequences, where MMP-2 and MT-MMPs showed an ability to hydrolyze a triple helix at an additional site (Gly-Gln bond).	Glycine	204-207	matrix metallopeptidase 2	Homo sapiens	67-71
23607342-0	2013	Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans.	Glycine	32-35	nucleoporin 98 and 96 precursor	Homo sapiens	70-75
17338550-7	2007	Differences in specificity between secreted and membrane-type (MT) MMPs were also observed for both sequences, where MMP-2 and MT-MMPs showed an ability to hydrolyze a triple helix at an additional site (Gly-Gln bond).	Glycine	204-207	matrix metallopeptidase 2	Homo sapiens	117-122
17338550-8	2007	Interruption of the triple helix had different effects on secreted MMPs and MT-MMPs, because MT-MMPs could not hydrolyze the Asn-Phe bond but instead cleaved the triple helix closer to the C terminus at a Gly-Gln bond.	Glycine	205-208	matrix metallopeptidase 2	Homo sapiens	67-71
17214961-3	2007	Here, we show that antagonists of and substitutions within the glycine-binding site of NR1 potentiate NR1/NR3 receptor function up to 25-fold, but inhibition or mutation of the NR3 glycine binding site reduces or abolishes receptor activation.	Glycine	63-70	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	106-109
17214961-3	2007	Here, we show that antagonists of and substitutions within the glycine-binding site of NR1 potentiate NR1/NR3 receptor function up to 25-fold, but inhibition or mutation of the NR3 glycine binding site reduces or abolishes receptor activation.	Glycine	181-188	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	177-180
17214961-4	2007	Thus, glycine bound to the NR1 subunit causes auto-inhibition of NR1/NR3 receptors whereas glycine binding to the NR3 subunits is required for opening of the ion channel.	Glycine	6-13	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	69-72
23607342-0	2013	Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans.	Glycine	44-47	nucleoporin 98 and 96 precursor	Homo sapiens	70-75
17214961-4	2007	Thus, glycine bound to the NR1 subunit causes auto-inhibition of NR1/NR3 receptors whereas glycine binding to the NR3 subunits is required for opening of the ion channel.	Glycine	91-98	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	114-117
23457265-2	2013	To determine the physiological function of TDP-43, we knocked out zebrafish Tardbp and its paralogue Tardbp (TAR DNA binding protein-like), which lacks the glycine-rich domain where ALS- and FTLD-TDP-associated mutations cluster.	Glycine	156-163	TAR DNA binding protein a	Danio rerio	101-107
22659408-0	2013	Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG).	Glycine	0-7	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	78-84
17265103-4	2007	Among the five NSP4 genotypes identified, those belonging to genotypes A1, B and C possess either a proline at position 138 or a glycine at 140, while those of A2, D and E lack these residues in the ISVD, suggesting conformational differences in this region among different NSP4s.	Glycine	129-136	serine protease 57	Homo sapiens	15-19
17089091-5	2007	Comparative analyses between Xtnr3 and Xnr5 revealed regions required for dimerization: (1) a conserved glycine, (2) the seventh cysteine, and (3) a putative alpha-helix located between the third and the fourth cysteines.	Glycine	104-111	nodal homolog 5	Xenopus tropicalis	39-43
23261614-0	2013	Analysis on structural, SHG efficiency, optical and mechanical properties of KDP single crystals influenced by Glycine doping.	Glycine	111-118	WNK lysine deficient protein kinase 1	Homo sapiens	77-80
23261614-1	2013	Good quality single crystals of potassium dihydrogen orthophosphate (KDP) were grown with different doping concentration of Glycine by conventional solution technique in aqueous solution.	Glycine	124-131	WNK lysine deficient protein kinase 1	Homo sapiens	69-72
23484211-2	2013	Based on these estimations, a three-dimensional model of Lys-Glu and Ala-Glu-Asp-Gly peptide interactions with DNA sites (GCAG and ATTTC) located in the promoter zones of genes encoding CD5, IL-2, MMP2, and Tram1 signal molecules.	Glycine	81-84	matrix metallopeptidase 2	Homo sapiens	197-201
17202595-4	2007	LHRH-I is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15) that cleaves the hormone at the Tyr(5)-Gly(6) bond.	Glycine	113-116	gonadotropin releasing hormone 1	Homo sapiens	0-6
23711493-7	2013	In PEPT1 or PEPT2 expressing oocytes Igly-gly was significantly increased by additional coexpression of JAK2.	Glycine	38-41	solute carrier family 15 (oligopeptide transporter), member 1 L homeolog	Xenopus laevis	3-8
17050777-7	2007	AQ-tetraamines could permeate the channel at very negative membrane potentials when the narrowest constriction of the channel was expanded by replacing the Asn residue at Asn616 of NR1 and NR2B with Gly, whereas Ant-tetraamines did not easily pass through the channel, apparently because of differences in the relative position of the head groups on AQ- and Ant-polyamines.	Glycine	199-202	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	189-193
23711493-7	2013	In PEPT1 or PEPT2 expressing oocytes Igly-gly was significantly increased by additional coexpression of JAK2.	Glycine	38-41	solute carrier family 15 member 2 L homeolog	Xenopus laevis	12-17
23711493-7	2013	In PEPT1 or PEPT2 expressing oocytes Igly-gly was significantly increased by additional coexpression of JAK2.	Glycine	38-41	Janus kinase 2 (a protein tyrosine kinase) L homeolog	Xenopus laevis	104-108
24124363-3	2013	In this study, we explore the preparation and characterization of gadolinium (Gd)-loaded poly (lactic-co-glycolic acid) (PLGA) particles surface modified with the Arg-Gly-Asp-Ser (RGDS) peptide for the detection of thrombus.	Glycine	167-170	ral guanine nucleotide dissociation stimulator	Homo sapiens	180-184
18058532-2	2007	With this in view, the residues R68 and Y60, supposed to be involved in the intersubunit interactions and in the catalytic site of CDA, were mutated to glutamine and glycine, respectively.	Glycine	166-173	cytidine deaminase	Homo sapiens	131-134
23105112-7	2012	Similarly, mutation of the residues alanine 262 and glycine 266 of an AXXXG dimerization motif flanking the gamma-secretase cleavage site within the p75(NTR) transmembrane domain alters the orientation of the domain and inhibits gamma-secretase cleavage of p75(NTR).	Glycine	52-59	PC4 and SFRS1 interacting protein 1	Homo sapiens	149-152
23105112-7	2012	Similarly, mutation of the residues alanine 262 and glycine 266 of an AXXXG dimerization motif flanking the gamma-secretase cleavage site within the p75(NTR) transmembrane domain alters the orientation of the domain and inhibits gamma-secretase cleavage of p75(NTR).	Glycine	52-59	neurotensin receptor 1	Homo sapiens	153-156
17141920-7	2007	Gly- and Ala-containing tachykinins are both encoded in the Drosophila tachykinin precursor, thus raising the question of whether DTKR can also distinguish between these two tachykinin types.	Glycine	0-3	Tachykinin	Drosophila melanogaster	71-81
22971924-4	2012	We found that a variable degree of loss of inhibition mutants is attainable by engineering glycine mutations along PLN"s loop domain.	Glycine	91-98	phospholamban	Homo sapiens	115-118
17157960-9	2007	DTK2, like Locusta tachykinin-1, was cleaved at the penultimate peptide bond (Gly(7)-Leu(8)), whereas the other Drosophila peptides were cleaved centrally at Xxx-Phe bonds.	Glycine	78-81	Tachykinin	Drosophila melanogaster	0-4
22971924-5	2012	Remarkably, a double glycine mutation results in a complete loss-of-function mutant, fully mimicking the phosphorylated state of PLN.	Glycine	21-28	phospholamban	Homo sapiens	129-132
22971346-1	2012	A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer.	Glycine	2-5	fibroblast growth factor receptor 4	Homo sapiens	108-113
23022347-0	2012	The survival motor neuron protein forms soluble glycine zipper oligomers.	Glycine	48-55	survival of motor neuron 1, telomeric	Homo sapiens	4-33
18605243-1	2007	The tripeptide FEG (Phe-Glu-Gly) and its D-isomer feG are potent anti-inflammatory peptides that reduce type I immediate hypersensitivity reactions (antigen-induced contraction of sensitized intestine), and inhibit the binding of CD16b (FCyRIII) antibody to human neutrophils.	Glycine	28-31	Fc gamma receptor IIIb	Homo sapiens	230-235
22575083-2	2012	For the human PR, mutations at Gly-722 on helix 3 and Met-759 on helix 5 alter responses to progesterone.	Glycine	31-34	progesterone receptor	Homo sapiens	14-16
17128993-3	2006	A collagen-like domain of human SP-A consists of 23 Gly-X-Y repeats with an interruption near the midpoint of this domain.	Glycine	52-55	surfactant protein A1	Homo sapiens	32-36
22575083-5	2012	This suggests that the cysteine to glycine replacement in helix 3 in the PR was important in the evolution of mammals.	Glycine	35-42	progesterone receptor	Homo sapiens	73-75
17128993-10	2006	These results indicate that the interruption of Gly-X-Y repeats in the SP-A molecule is critical for the formation of a flower bouquet-like octadecamer and contributes to SP-A"s capacity to aggregate phospholipid liposomes.	Glycine	48-51	surfactant protein A1	Homo sapiens	71-75
17128993-10	2006	These results indicate that the interruption of Gly-X-Y repeats in the SP-A molecule is critical for the formation of a flower bouquet-like octadecamer and contributes to SP-A"s capacity to aggregate phospholipid liposomes.	Glycine	48-51	surfactant protein A1	Homo sapiens	171-175
23012891-3	2012	As a result, it was shown that there were significant relationships between SD (self-directedness) and 49Ser/Gly (rs1801252) in ADRB1, P (persistence) and 389Arg/Gly (rs1801253) in ADRB1, and ST (self-transcendence) and 27Gln/Glu (rs1042714) in ADRB2 overall.	Glycine	109-112	adrenoceptor beta 1	Homo sapiens	128-133
23012891-3	2012	As a result, it was shown that there were significant relationships between SD (self-directedness) and 49Ser/Gly (rs1801252) in ADRB1, P (persistence) and 389Arg/Gly (rs1801253) in ADRB1, and ST (self-transcendence) and 27Gln/Glu (rs1042714) in ADRB2 overall.	Glycine	109-112	adrenoceptor beta 1	Homo sapiens	181-186
23012891-4	2012	Among the male subjects, there were further significant relationships between ST and 49Ser/Gly in ADRB1, NS (novelty-seeking), HA (harm avoidance) and P and 389Arg/Gly in ADRB1, and P and 64Arg/Trp(rsrs4994) in ADRB3.	Glycine	91-94	adrenoceptor beta 1	Homo sapiens	98-103
17361716-1	2006	A new molybdovanadophosphoric heteropoly compound containing glycine with tri-vanadium-substituted Dawson structure, namely C2 H14O64P2Mo1515V3 x 5H2O was synthesized and structurally characterized by elemental analysis, including IR spectra, X-ray and TGA powder diffraction.	Glycine	61-68	T-box transcription factor 1	Homo sapiens	253-256
18487326-6	2008	The processed NopT exposed a glycine (G50) to the N terminus, which is predicted to be myristoylated in eukaryotic cells.	Glycine	29-36	YopT-type cysteine protease domain-containing protein	Sinorhizobium fredii NGR234	14-18
23012891-5	2012	Among the female subjects, there were also significant relationships between SD and 49Ser/Gly in ADRB1, and C (cooperativeness) and 389Arg/Gly in ADRB1.	Glycine	90-93	adrenoceptor beta 1	Homo sapiens	97-102
22610453-2	2012	Substitution of Arg for the generally conserved Gly-193 has been implicated as a critical determinant of the unusual behavior of mesotrypsin toward protein protease inhibitors.	Glycine	48-51	serine protease 3	Homo sapiens	129-140
18430863-3	2008	In the present study, we further characterize the human mGluR2 (hmGluR2) potentiator binding site by showing that the substitution of the three amino acids found to be required for hmGluR2 potentiation, specifically Ser(688), Gly(689), and Asn(735), with the homologous hmGluR3 amino acids, inactivates the positive allosteric modulator activity of several structurally unique mGluR2 potentiators.	Glycine	226-229	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	56-62
18430863-3	2008	In the present study, we further characterize the human mGluR2 (hmGluR2) potentiator binding site by showing that the substitution of the three amino acids found to be required for hmGluR2 potentiation, specifically Ser(688), Gly(689), and Asn(735), with the homologous hmGluR3 amino acids, inactivates the positive allosteric modulator activity of several structurally unique mGluR2 potentiators.	Glycine	226-229	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	65-71
18413142-2	2008	Using hexameric peptide library of FN-III(8-11) scan, we identified the ALNGR (Ala-Leu-Asn-Gly-Arg) peptide that induced cell adhesion as well as RGDS (Arg-Gly-Asp-Ser) peptide.	Glycine	91-94	ral guanine nucleotide dissociation stimulator	Homo sapiens	146-150
18499099-9	2008	We demonstrated that when 3T3-L1 cells were treated with glycine, IL-6, resistin and TNF-alpha mRNA expression was decreased, but surprisingly adiponectin and PPAR-gamma were up-regulated.	Glycine	57-64	peroxisome proliferator activated receptor gamma	Mus musculus	159-169
22812023-5	2004	In terms of agonist requirement and channel operation, the three subunit families exhibit distinct properties; NR1 and NR3 require glycine as the agonist and have no binding site for glutamate, whereas NR2 is activated by glutamate.	Glycine	131-138	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	119-122
22576375-1	2012	Crystal specimens of the gamma-polymorph of achiral glycine which crystallize in space groups P31 and P32 as determined by the anomalous X-ray scattering method are shown to be laevorotatory and dextrorotatory, respectively, as determined by optical rotation of the crystals.	Glycine	52-59	inhibitor of growth family member 2	Homo sapiens	102-105
22560905-2	2012	The integrins recognize a short tripeptide motif of arg-lys-cys (RKC) in CD23, and peptides containing this motif inhibit the binding of CD23 to B cells and monocytes; neither fibronectin, nor vitronectin, which contain arg-gly-asp motifs, inhibit binding of RKC-containing peptides to cells.	Glycine	224-227	Fc epsilon receptor II	Homo sapiens	137-141
18591903-3	2008	The purpose of the present study is to assess the clinical effects of real life usage of beta2-agonist (long-acting beta2-agonist, regular use of short-acting beta2 agonist, or oral beta2-agonist), as an add-on medication to inhaled steroids, in Arg/Arg and Gly/Gly patients with asthma.	Glycine	258-261	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	89-94
18591903-3	2008	The purpose of the present study is to assess the clinical effects of real life usage of beta2-agonist (long-acting beta2-agonist, regular use of short-acting beta2 agonist, or oral beta2-agonist), as an add-on medication to inhaled steroids, in Arg/Arg and Gly/Gly patients with asthma.	Glycine	262-265	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	89-94
18591903-4	2008	METHODS: In a retrospective analysis of outpatient records, 27 patients with Arg/Arg and 35 patients with Gly/Gly had regular usage of beta2-agonist, whereas 37 patients with Arg/Arg and 29 patients with Gly/Gly had as-needed usage of beta2-agonist.	Glycine	106-109	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	135-140
18591903-4	2008	METHODS: In a retrospective analysis of outpatient records, 27 patients with Arg/Arg and 35 patients with Gly/Gly had regular usage of beta2-agonist, whereas 37 patients with Arg/Arg and 29 patients with Gly/Gly had as-needed usage of beta2-agonist.	Glycine	110-113	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	135-140
18591903-4	2008	METHODS: In a retrospective analysis of outpatient records, 27 patients with Arg/Arg and 35 patients with Gly/Gly had regular usage of beta2-agonist, whereas 37 patients with Arg/Arg and 29 patients with Gly/Gly had as-needed usage of beta2-agonist.	Glycine	110-113	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	135-140
18591903-4	2008	METHODS: In a retrospective analysis of outpatient records, 27 patients with Arg/Arg and 35 patients with Gly/Gly had regular usage of beta2-agonist, whereas 37 patients with Arg/Arg and 29 patients with Gly/Gly had as-needed usage of beta2-agonist.	Glycine	110-113	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	135-140
22913202-10	2012	Fatty acid transport protein (FATP) was significantly elevated in the different glycine supplemented groups.	Glycine	80-87	CD36 molecule	Rattus norvegicus	0-28
18591903-6	2008	RESULTS: In patients with Gly/Gly genotype, compared with as-needed usage of beta2-agonist, the regular usage of beta2-agonist was associated with greater improvement in FEV1 in every index (p=0.027-0.041).	Glycine	26-29	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	113-118
18591903-6	2008	RESULTS: In patients with Gly/Gly genotype, compared with as-needed usage of beta2-agonist, the regular usage of beta2-agonist was associated with greater improvement in FEV1 in every index (p=0.027-0.041).	Glycine	30-33	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	113-118
18591903-8	2008	CONCLUSION: Gly/Gly and Arg/Arg genotype responses to regular usage of beta2-agonists may differ in patients with asthma.	Glycine	12-15	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	71-76
18591903-8	2008	CONCLUSION: Gly/Gly and Arg/Arg genotype responses to regular usage of beta2-agonists may differ in patients with asthma.	Glycine	16-19	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	71-76
22913202-10	2012	Fatty acid transport protein (FATP) was significantly elevated in the different glycine supplemented groups.	Glycine	80-87	CD36 molecule	Rattus norvegicus	30-34
22553026-2	2012	NMDA receptors are activated upon simultaneous binding of coagonists glycine and glutamate to the GluN1 and GluN2 subunits, respectively.	Glycine	69-76	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	98-103
22553026-4	2012	Here, we show the mechanism of action for 3-chloro-4-fluoro-N-[(4-[(2-(phenylcarbonyl)hydrazino)carbonyl]phenyl)methyl]-benzenesulfonamide (TCN-201), a new GluN1/GluN2A-selective NMDA receptor antagonist whose inhibition can be surmounted by glycine.	Glycine	242-249	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	156-161
22468768-6	2012	The UV-monitored thermal melting curves show that the anticodon arm of tRNA(Gly,UCC) with a loop-closing C-A(+) base pair melts at a temperature 10  C lower than those of tRNA(Gly,GCC) and np-tRNA(Gly,UCC).	Glycine	76-79	guanylate cyclase 2C	Homo sapiens	171-183
18400955-2	2008	We previously reported that glycine-independent desensitization decreases during hippocampal neuronal development, correlating with NMDAR synaptic localization and association with postsynaptic density 95 (PSD-95).	Glycine	28-35	discs large MAGUK scaffold protein 4	Homo sapiens	181-204
22468768-10	2012	The anticodon loop of tRNA(Gly,GCC) becomes more dynamic and disordered in the presence of multivalent cations, whereas metal ion coordination in the anticodon loops of tRNA(Gly,UCC) and np-tRNA(Gly,UCC) establishes conformational homogeneity.	Glycine	174-177	guanylate cyclase 2C	Homo sapiens	22-34
18400955-2	2008	We previously reported that glycine-independent desensitization decreases during hippocampal neuronal development, correlating with NMDAR synaptic localization and association with postsynaptic density 95 (PSD-95).	Glycine	28-35	discs large MAGUK scaffold protein 4	Homo sapiens	206-212
21909137-8	2012	Thus, although a full length of rictor is required to interact with its binding partner Sin1, a single amino acid of rictor Gly-934 controls its interaction with Sin1 and assembly of mTORC2.	Glycine	124-127	CREB regulated transcription coactivator 2	Mus musculus	183-189
22538654-1	2012	Replacement of glycine 227 in the fifth WD40 motif of alpha-COP/Ret1p/Soo1p by charged or aromatic amino acids is responsible for the temperature-dependent osmo-sensitivity of Saccharomyces cerevisiae, while truncations of WD40 motifs exerted a reduction in cell growth rate and impairment in assembly of cell-wall associated proteins such as enolase and Gas1p.	Glycine	15-22	coatomer subunit alpha	Saccharomyces cerevisiae S288C	70-75
18381282-2	2008	The prion-forming domain of the yeast Sup35 protein is rich in glutamine, asparagine, tyrosine, and glycine residues, which may define its prion properties.	Glycine	100-107	translation termination factor GTPase eRF3	Saccharomyces cerevisiae S288C	38-43
22425803-2	2012	Elevation of glycine concentrations by inhibition of its reuptake in the vicinity of NMDA receptors may positively influence receptor functions as glycine B binding site on NR1 receptor subunit is not saturated in physiological conditions.	Glycine	13-20	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	173-176
18412318-6	2008	PEGylated peptides [Gly (8),Aib (22)]GLP-1(7-37)-Cys ((PEG))-Ala-NH2 (23) and c[Glu (22)-Lys (26)][Gly (8)]GLP-1(7-37)-Cys ((PEG))-Ser-Gly-NH2 (24) retained picomolar functional potency and avid receptor binding properties.	Glycine	20-23	glucagon like peptide 1 receptor	Homo sapiens	37-42
18412318-6	2008	PEGylated peptides [Gly (8),Aib (22)]GLP-1(7-37)-Cys ((PEG))-Ala-NH2 (23) and c[Glu (22)-Lys (26)][Gly (8)]GLP-1(7-37)-Cys ((PEG))-Ser-Gly-NH2 (24) retained picomolar functional potency and avid receptor binding properties.	Glycine	99-102	glucagon like peptide 1 receptor	Homo sapiens	37-42
22259020-4	2012	These studies showed that aspartate-8, histidine-11, glycine-6, proline-4, arginine-1, and proline-9, arranged in an order of importance, were critical, while threonine-2, valine-3, serine-5, and the previously assigned hydroxylation and arabinosylation residue proline-7 were trivial for the endogenous CLV3 function in SAM maintenance.	Glycine	53-60	CLAVATA3	Arabidopsis thaliana	304-308
18353960-5	2008	These interactions required the TGB2 glycine 40 and the TGB3 isoleucine 108 residues, and BSMV mutants containing these amino acid substitution were unable to move from cell to cell.	Glycine	37-44	pro-platelet basic protein pseudogene 1	Homo sapiens	32-36
18421157-2	2008	The Neh2 domain of Nrf2 interacts with Keap1 at the bottom region of the Kelch/beta-propeller domain which is formed by double-glycine repeat and C-terminal region domains (Keap1-DC).	Glycine	127-134	nei like DNA glycosylase 2	Homo sapiens	4-8
21826105-2	2012	MRE11 is known to be arginine methylated by PRMT1 within its glycine-arginine-rich (GAR) motif.	Glycine	61-68	MRE11A homolog A, double strand break repair nuclease	Mus musculus	0-5
18238779-5	2008	Studies of chimeric proteases, consisting of various parts of the MMP-2 catalytic domain and those of MMP-7 (matrilysin) or MMP-9 (gelatinase B), further revealed that Ala(88) and Gly(94) in the non-prime side and Tyr(145) and Thr(146) in the prime side of the substrate-binding cleft of MMP-2 contribute separately to the selective inhibition.	Glycine	180-183	matrix metallopeptidase 2	Homo sapiens	66-71
22103682-7	2012	We further demonstrate that the C-terminal glycine-arginine rich domain of nucleolin serves as the predominant binding domain for direct interaction with p53.	Glycine	43-50	nucleolin	Homo sapiens	75-84
18331634-6	2008	Patients with the ADRB1 Gly389 polymorphism were at higher risk for the composite outcome due to higher rates of myocardial infarction (adjusted hazard ratio [HR] 3.63, 95% confidence interval [95%CI] 1.17-11.28; Gly/Gly vs. Arg/Arg HR 4.14, 95%CI 0.88-19.6).	Glycine	24-27	adrenoceptor beta 1	Homo sapiens	18-23
18331634-6	2008	Patients with the ADRB1 Gly389 polymorphism were at higher risk for the composite outcome due to higher rates of myocardial infarction (adjusted hazard ratio [HR] 3.63, 95% confidence interval [95%CI] 1.17-11.28; Gly/Gly vs. Arg/Arg HR 4.14, 95%CI 0.88-19.6).	Glycine	213-216	adrenoceptor beta 1	Homo sapiens	18-23
22103682-9	2012	Conversely, the adjacent glycine-arginine rich domain of nucleolin interacted with p53 causing a modest stimulatory effect on p53 ubiquitination.	Glycine	25-32	nucleolin	Homo sapiens	57-66
22738642-0	2012	Identification of a new HBA1 gene mutation (HBA1:c.301-2A&gt;T) in cis with Hb Riccarton (HBA1:c.154G&gt;A) [alpha51(CE9)Gly Ser].	Glycine	121-124	hemoglobin subunit alpha 1	Homo sapiens	24-28
18077447-2	2008	Whereas substitution of arginine for the highly conserved glycine 193 in the trypsin active site has been implicated as a critical factor in the inhibitor resistance of mesotrypsin, how this substitution leads to accelerated inhibitor cleavage is not clear.	Glycine	58-65	serine protease 3	Homo sapiens	169-180
22738642-0	2012	Identification of a new HBA1 gene mutation (HBA1:c.301-2A&gt;T) in cis with Hb Riccarton (HBA1:c.154G&gt;A) [alpha51(CE9)Gly Ser].	Glycine	121-124	hemoglobin subunit alpha 1	Homo sapiens	44-48
22738642-0	2012	Identification of a new HBA1 gene mutation (HBA1:c.301-2A&gt;T) in cis with Hb Riccarton (HBA1:c.154G&gt;A) [alpha51(CE9)Gly Ser].	Glycine	121-124	hemoglobin subunit alpha 1	Homo sapiens	44-48
22619531-5	2012	PEG hydrogel-coated MIONPs were further functionalized with the fibronectin-derived arginine-glycine-aspartic acid-serine (RGDS) sequence, in order to achieve a biofunctional PEG hydrogel layer around the nanoparticles.	Glycine	93-100	ral guanine nucleotide dissociation stimulator	Homo sapiens	123-127
18096599-1	2008	Early in development, GABA and glycine exert excitatory action that turns to inhibition due to modification of the chloride equilibrium potential (E(Cl)) controlled by the KCC2 and NKCC1 transporters.	Glycine	31-38	solute carrier family 12, member 2	Mus musculus	181-186
22037604-11	2012	In the most severely affected DTS-L3 mutant, we have identified four missense mutations within the coding region of the col4a1 gene two of which affected the Y within the Gly-X-Y unit and a 3" UTR point mutation.	Glycine	171-174	Collagen type IV alpha 1	Drosophila melanogaster	120-126
18272676-6	2008	Moreover, M3c residues at or below A651(NR2B, A7 in SYTANLAAF) react with external methanethiosulfonate (MTS) reagents approximately 500 to 1000-fold faster in the presence than in the absence of agonists NMDA and glycine.	Glycine	214-221	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	40-44
17172352-7	2006	Rescue of tha2 mutants and tha1 tha2 double mutants by overproduction of feedback-insensitive Thr deaminase (OMR1) shows that Gly formation by THA1 and THA2 is not essential in Arabidopsis.	Glycine	126-129	threonine aldolase 2	Arabidopsis thaliana	10-14
17172352-7	2006	Rescue of tha2 mutants and tha1 tha2 double mutants by overproduction of feedback-insensitive Thr deaminase (OMR1) shows that Gly formation by THA1 and THA2 is not essential in Arabidopsis.	Glycine	126-129	threonine aldolase 2	Arabidopsis thaliana	152-156
22106047-1	2012	Sites of ubiquitin modification have been identified by mass spectrometry based on the increase in molecular mass of a tryptic peptide carrying two additional glycine residues from the ubiquitin moiety.	Glycine	159-166	ubiquitin	Saccharomyces cerevisiae S288C	9-18
18222967-4	2008	LHRH-I is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15) that cleaves the hormone at the fifth and sixth bond of the decapeptide (Tyr(5)-Gly(6)) to form LHRH-(1-5).	Glycine	154-157	gonadotropin releasing hormone 1	Homo sapiens	0-6
18222967-4	2008	LHRH-I is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15) that cleaves the hormone at the fifth and sixth bond of the decapeptide (Tyr(5)-Gly(6)) to form LHRH-(1-5).	Glycine	154-157	gonadotropin releasing hormone 1	Homo sapiens	0-4
22106059-2	2012	Cleavage of the C(alpha)-N bond of a C-terminal glycine yields the alpha-amidated peptide in a reaction catalyzed by peptidylglycine alpha-amidating monooxygenase (PAM).	Glycine	48-55	peptidylglycine alpha-amidating monooxygenase	Mus musculus	164-167
21898593-2	2011	We have previously shown that the impaired Arg-Gly-Asp (RGD) sequence of osteopontin inhibits renal crystal formation by using OPN-transgenic mice and OPN-knockout (OPN-KO) mice.	Glycine	47-50	secreted phosphoprotein 1	Mus musculus	73-84
17900649-2	2008	Thus, we mutated Phe 436, a bulky amino acid with aromatic side chain, at the putative dNTP-binding cleft in reverse transcriptase (RT) domain of P protein to smaller amino acids (Gly or Val), and examined RNA polymerase activity.	Glycine	180-183	OCA2 melanosomal transmembrane protein	Homo sapiens	146-155
17959602-1	2008	N-Methyl-D-aspartate (NMDA) receptors are tetrameric protein complexes composed of the glycine-binding NR1 subunit with a glutamate-binding NR2 and/or glycine-binding NR3 subunit.	Glycine	151-158	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	167-170
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	150-157	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	51-54
17959602-2	2008	Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by glycine alone.	Glycine	150-157	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	209-212
16822871-8	2006	Therefore, a pro-Crp4(20-92) variant with Gly substitutions at all pro-Crp4(20-43) Asp and Glu positions ((DE/G)-pro-Crp4) was prepared, and it was bactericidal and lysed phospholipid vesicles under conditions where native pro-Crp4(20-92) lacks activity.	Glycine	42-45	defensin, alpha, 4	Mus musculus	17-21
16884688-3	2006	Here, we describe mutations within the neuronal glycine transporter 2 gene (GLYT2, or SLC6A5, ) of hyperekplexia patients, whose symptoms cannot be attributed to glycine receptor mutations.	Glycine	48-55	solute carrier family 6 member 5	Homo sapiens	76-81
16884688-3	2006	Here, we describe mutations within the neuronal glycine transporter 2 gene (GLYT2, or SLC6A5, ) of hyperekplexia patients, whose symptoms cannot be attributed to glycine receptor mutations.	Glycine	48-55	solute carrier family 6 member 5	Homo sapiens	86-92
21820454-8	2011	Impeding GluA2/GRIP/PICK1 interaction facilitated the NMDA/glycine/(S)AMPA-induced release of [(3)H]D-ASP, while competing for GluA2/NSF interaction reduced it, indicating that NMDA receptor favours AMPA receptor insertion in synaptosomal plasmamembranes.	Glycine	59-66	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	9-14
16922515-2	2006	We mapped the region of methylation to the C-terminal arginine-glycine-rich residues encoded by FMR1 exon 15.	Glycine	63-70	fragile X mental retardation protein 1	Oryctolagus cuniculus	96-100
21820454-8	2011	Impeding GluA2/GRIP/PICK1 interaction facilitated the NMDA/glycine/(S)AMPA-induced release of [(3)H]D-ASP, while competing for GluA2/NSF interaction reduced it, indicating that NMDA receptor favours AMPA receptor insertion in synaptosomal plasmamembranes.	Glycine	59-66	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	127-132
21820454-8	2011	Impeding GluA2/GRIP/PICK1 interaction facilitated the NMDA/glycine/(S)AMPA-induced release of [(3)H]D-ASP, while competing for GluA2/NSF interaction reduced it, indicating that NMDA receptor favours AMPA receptor insertion in synaptosomal plasmamembranes.	Glycine	59-66	N-ethylmaleimide sensitive fusion protein	Mus musculus	133-136
21382104-7	2011	The predicted peptide, with two typical motifs of Trp-Cys-Gly-His-Cys-Lys (WCGHCK) which is a hallmark of the PDI family, has high homology to that of bovine (99.21%), human (95.05%), rat (89.50%) and mouse (90.89%).	Glycine	58-61	prolyl 4-hydroxylase subunit beta	Bos taurus	110-113
16802828-6	2006	Saturation Transfer Difference (STD) NMR with one of these inhibitors, with linker structure (Asp-Gly-AMAB-Gly-Asp) and K(D) = 42 nM for GSTA1-1, demonstrates that the Asp-Gly linker interacts tightly with GSTA1-1, but not P1-1.	Glycine	98-101	glutathione S-transferase alpha 1	Homo sapiens	137-144
21225462-2	2011	Through PCR-RFLP methods and DNA sequencing, an allelic variant corresponding to the A G mutations and Aspartic (Asp) to Glycine (Gly) amino acid replacement at positions 526745 in the exon 25 of bovine CACNA2D1 gene could be detected.	Glycine	121-128	calcium voltage-gated channel auxiliary subunit alpha2delta 1	Bos taurus	203-211
16723732-2	2006	To elucidate the roles of potentially crucial amino acids, we produced site-directed mutants of connexins Cx40 and Cx43 (Cx40E12S,E13G and Cx43D12S,K13G) in which the charged amino acids at positions 12 and 13 were replaced with serine and glycine as found in Cx32.	Glycine	240-247	gap junction protein alpha 1	Homo sapiens	115-119
16489129-7	2006	The release evoked by NMDA/glycine/Tat depends on metabotropic glutamate receptor 1 (mGluR1) activation, since it was halved by mGluR1 antagonists.	Glycine	27-34	glutamate metabotropic receptor 1	Homo sapiens	50-83
21225462-2	2011	Through PCR-RFLP methods and DNA sequencing, an allelic variant corresponding to the A G mutations and Aspartic (Asp) to Glycine (Gly) amino acid replacement at positions 526745 in the exon 25 of bovine CACNA2D1 gene could be detected.	Glycine	121-124	calcium voltage-gated channel auxiliary subunit alpha2delta 1	Bos taurus	203-211
16489129-7	2006	The release evoked by NMDA/glycine/Tat depends on metabotropic glutamate receptor 1 (mGluR1) activation, since it was halved by mGluR1 antagonists.	Glycine	27-34	glutamate metabotropic receptor 1	Homo sapiens	85-91
16489129-7	2006	The release evoked by NMDA/glycine/Tat depends on metabotropic glutamate receptor 1 (mGluR1) activation, since it was halved by mGluR1 antagonists.	Glycine	27-34	glutamate metabotropic receptor 1	Homo sapiens	128-134
21859715-11	2011	This analysis revealed that the Gly-Gly motif formed by Gly-65 and Gly-66 and the beta-strand side chain of Tyr-70 are crucial for DNA binding by His-tagged Mor.	Glycine	32-35	Mor	Escherichia phage Mu	157-160
16672841-1	2006	INTRODUCTION: Several common polymorphisms of the beta2 adrenergic (ADRB2) have been described including a Glycine (Gly) for arginine (Arg) substitution at amino acid 16.	Glycine	107-114	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	50-55
16672841-1	2006	INTRODUCTION: Several common polymorphisms of the beta2 adrenergic (ADRB2) have been described including a Glycine (Gly) for arginine (Arg) substitution at amino acid 16.	Glycine	107-110	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	50-55
21859715-11	2011	This analysis revealed that the Gly-Gly motif formed by Gly-65 and Gly-66 and the beta-strand side chain of Tyr-70 are crucial for DNA binding by His-tagged Mor.	Glycine	36-39	Mor	Escherichia phage Mu	157-160
21859715-11	2011	This analysis revealed that the Gly-Gly motif formed by Gly-65 and Gly-66 and the beta-strand side chain of Tyr-70 are crucial for DNA binding by His-tagged Mor.	Glycine	36-39	Mor	Escherichia phage Mu	157-160
21859715-11	2011	This analysis revealed that the Gly-Gly motif formed by Gly-65 and Gly-66 and the beta-strand side chain of Tyr-70 are crucial for DNA binding by His-tagged Mor.	Glycine	36-39	Mor	Escherichia phage Mu	157-160
21621561-4	2011	Here, we show that the Ala or Gly-extended GLP-1/IgG-Fc fusion protein is resistant to DPP-IV and has increased half-life in vivo.	Glycine	30-33	glucagon	Mus musculus	43-48
16611982-0	2006	Cdc37 interacts with the glycine-rich loop of Hsp90 client kinases.	Glycine	25-32	cell division cycle 37, HSP90 cochaperone	Homo sapiens	0-5
16611982-2	2006	Phage display technology and liquid chromatography-tandem mass spectrometry (which identifies a total of 33 proteins) consistently identify a unique sequence, GXFG, as a Cdc37-interacting motif that occurs in the canonical glycine-rich loop (GXGXXG) of protein kinases, regardless of their dependence on Hsp90 or Cdc37.	Glycine	223-230	cell division cycle 37, HSP90 cochaperone	Homo sapiens	170-175
16611982-2	2006	Phage display technology and liquid chromatography-tandem mass spectrometry (which identifies a total of 33 proteins) consistently identify a unique sequence, GXFG, as a Cdc37-interacting motif that occurs in the canonical glycine-rich loop (GXGXXG) of protein kinases, regardless of their dependence on Hsp90 or Cdc37.	Glycine	223-230	cell division cycle 37, HSP90 cochaperone	Homo sapiens	313-318
21790901-0	2011	The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors.	Glycine	58-65	glutamate receptor, ionotropic, kainate 1	Mus musculus	4-10
16611982-3	2006	The glycine-rich motif of Raf-1 (GSGSFG) is necessary for its association with Cdc37; nevertheless, the N lobe of Raf-1 (which includes the GSGSFG motif) on its own cannot interact with Cdc37.	Glycine	4-11	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	26-31
16611982-3	2006	The glycine-rich motif of Raf-1 (GSGSFG) is necessary for its association with Cdc37; nevertheless, the N lobe of Raf-1 (which includes the GSGSFG motif) on its own cannot interact with Cdc37.	Glycine	4-11	cell division cycle 37, HSP90 cochaperone	Homo sapiens	79-84
16611982-3	2006	The glycine-rich motif of Raf-1 (GSGSFG) is necessary for its association with Cdc37; nevertheless, the N lobe of Raf-1 (which includes the GSGSFG motif) on its own cannot interact with Cdc37.	Glycine	4-11	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	114-119
16611982-6	2006	Thus, although a region in the C termini of protein kinases may be crucial for accomplishing and maintaining their interaction with Cdc37, we conclude that the N-terminal glycine-rich loop of protein kinases is essential for physically associating with Cdc37.	Glycine	171-178	cell division cycle 37, HSP90 cochaperone	Homo sapiens	132-137
16611982-6	2006	Thus, although a region in the C termini of protein kinases may be crucial for accomplishing and maintaining their interaction with Cdc37, we conclude that the N-terminal glycine-rich loop of protein kinases is essential for physically associating with Cdc37.	Glycine	171-178	cell division cycle 37, HSP90 cochaperone	Homo sapiens	253-258
21800130-2	2011	So far, only two functional alleles differing at only one amino acid position (non-synonymous mutation) in the alpha2 heavy chain domain, where an arginine in position 107 in HLA-E*0101 is replaced by a glycine in HLA-E*0103, have been reported.	Glycine	203-210	major histocompatibility complex, class I, E	Homo sapiens	175-180
16478649-2	2006	A structurally unique member of the family is galectin-3; in addition to the CRD it contains a proline- and glycine-rich N-terminal domain (ND) through which is able to form oligomers.	Glycine	108-115	galectin 3	Homo sapiens	46-56
16632906-0	2006	Mutations of conserved glycine residues within the membrane-spanning domain of human immunodeficiency virus type 1 gp41 can inhibit membrane fusion and incorporation of Env onto virions.	Glycine	23-30	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	169-172
16632906-1	2006	The membrane-spanning domain (MSD) of HIV-1 envelope protein (Env) has an additional glycine residue within a well-conserved putative transmembrane helix-helix interaction motif, GXXXG, and forms a G(690)G(691)XXG(694) sequence (G, glycine; X, any residues; the numbering indicates the position within the Env of an infectious molecular clone, HXB2).	Glycine	85-92	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	44-60
16632906-1	2006	The membrane-spanning domain (MSD) of HIV-1 envelope protein (Env) has an additional glycine residue within a well-conserved putative transmembrane helix-helix interaction motif, GXXXG, and forms a G(690)G(691)XXG(694) sequence (G, glycine; X, any residues; the numbering indicates the position within the Env of an infectious molecular clone, HXB2).	Glycine	85-92	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	62-65
21800130-2	2011	So far, only two functional alleles differing at only one amino acid position (non-synonymous mutation) in the alpha2 heavy chain domain, where an arginine in position 107 in HLA-E*0101 is replaced by a glycine in HLA-E*0103, have been reported.	Glycine	203-210	major histocompatibility complex, class I, E	Homo sapiens	214-219
21544738-2	2011	The active form of ISG15 is conjugated to target proteins via the C-terminal glycine residue through an isopeptide bond in a manner similar to ubiquitin.	Glycine	77-84	ISG15 ubiquitin like modifier	Homo sapiens	19-24
16410248-6	2006	FAP also cleaved formyl-, benzyloxycarbonyl-, biotinyl-, and peptidyl-Gly-Pro substrates, which DPP-4 cleaved poorly, suggesting an N-acyl-Gly-Pro motif for inhibitor design.	Glycine	70-73	fibroblast activation protein alpha	Homo sapiens	0-3
21896756-1	2011	Mouse ES cells use a mitochondrial threonine dehydrogenase (TDH) enzyme to catabolize threonine into glycine and acetyl-CoA.	Glycine	101-108	L-threonine dehydrogenase	Mus musculus	35-58
16380387-7	2006	The point mutant Asp205 --&gt; Gly (in Ypa1) identified this amino acid as essential for both activities.	Glycine	31-34	peptidylprolyl isomerase RRD1	Saccharomyces cerevisiae S288C	39-43
21896756-1	2011	Mouse ES cells use a mitochondrial threonine dehydrogenase (TDH) enzyme to catabolize threonine into glycine and acetyl-CoA.	Glycine	101-108	L-threonine dehydrogenase	Mus musculus	60-63
21896756-6	2011	Such efforts led to the discovery of a class of quinazolinecarboxamide (Qc) compounds that inhibit the ability of the TDH enzyme to catabolize threonine into glycine and acetyl-CoA.	Glycine	158-165	L-threonine dehydrogenase	Mus musculus	118-121
22100794-5	2011	In HLA-E*0101 it is arginine and in HLA-E*0103 it is glycine.	Glycine	53-60	major histocompatibility complex, class I, E	Homo sapiens	3-8
16480718-0	2006	Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity.	Glycine	96-99	fibroblast activation protein alpha	Homo sapiens	36-65
16480718-3	2006	FAP required substrates with Pro at P(1) and Gly or d-amino acids at P(2) and preferred small, uncharged amino acids at P(3), but tolerated most amino acids at P(4), P(1)(") and P(2)(").	Glycine	45-48	fibroblast activation protein alpha	Homo sapiens	0-3
16601880-0	2006	Genetic heterogeneity of the GLDC gene in 28 unrelated patients with glycine encephalopathy.	Glycine	69-76	glycine decarboxylase	Homo sapiens	29-33
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	FAM3 metabolism regulating signaling molecule B	Homo sapiens	202-207
18296366-10	2008	Phgdh deletion drastically reduced serine and glycine levels in the body.	Glycine	46-53	phosphoglycerate dehydrogenase	Homo sapiens	0-5
22100794-5	2011	In HLA-E*0101 it is arginine and in HLA-E*0103 it is glycine.	Glycine	53-60	major histocompatibility complex, class I, E	Homo sapiens	36-41
18601605-0	2008	The silent hemoglobin alpha chain variant Hb Riccarton [alpha51(CE9)Gly--&gt;Ser] may affect HbA1c determination on the HLC-723 G7 analyzer.	Glycine	68-71	hemoglobin subunit alpha 2	Homo sapiens	11-33
21876188-7	2011	DHFRL1 expression in CHO glyC, a previously uncharacterized mutant glycine auxotrophic cell line, rescued the glycine auxotrophy.	Glycine	67-74	dihydrofolate reductase 2	Homo sapiens	0-6
18654886-2	2008	We describe the clinical and hematological findings in two cases from independent families of Albanian origin, who have an interaction of the codon 59 (Gly--&gt;Asp) alpha2-globin gene variant in trans to a 3.7 kb alpha(+)-thal deletion (alpha(codon 59)alpha/-alpha).	Glycine	152-155	hemoglobin subunit alpha 2	Homo sapiens	166-179
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	RASD family member 2	Homo sapiens	304-308
21876188-7	2011	DHFRL1 expression in CHO glyC, a previously uncharacterized mutant glycine auxotrophic cell line, rescued the glycine auxotrophy.	Glycine	110-117	dihydrofolate reductase 2	Homo sapiens	0-6
21455835-3	2011	The PII helical structure between the third and fifth glycine in the middle motif was shown, through site mutation, to be critical for the enzyme protective function of soybean Em (LEA1) conserved domain under freezing stress.	Glycine	54-61	uncharacterized protein LOC100802292	Glycine max	181-185
17153626-3	2006	Taurine interaction with glycine and GABAA receptors causes depolarization of striatal medium spiny cells (Chepkova et al., 2002) which is enhanced by taurine electrogenic uptake by TauT (Sarkar et al., 2003).	Glycine	25-32	solute carrier family 6 member 6	Homo sapiens	182-186
16263090-5	2005	Characterization of the FGF3 binding domain of rpS2 showed that both the Arg-Gly-rich N-terminal region and a short carboxyl-terminal sequence of rpS2 are necessary for FGF3 binding.	Glycine	77-80	fibroblast growth factor 3	Homo sapiens	24-28
17962328-3	2008	We show that the potency of a variety of endogenous and synthetic glycine-site coagonists varies between recombinant NMDARs such that the highest potency is seen at NR2D-containing and the lowest at NR2A-containing NMDARs.	Glycine	66-73	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	165-169
17962328-4	2008	This heterogeneity is specified by the particular NR2 subunit within the NMDAR complex since the glycine-binding NR1 subunit is common to all NMDARs investigated.	Glycine	97-104	nodal homolog 2 L homeolog	Xenopus laevis	50-53
17962328-6	2008	Glycine concentration-response curves for NMDARs containing NR2A subunits including the NR2D S1 region gave mean glycine EC(50) values similar to NR2A(WT)-containing NMDARs.	Glycine	0-7	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	88-92
17962328-7	2008	However, receptors containing NR2A subunits including the NR2D S2 region or both NR2D S1 and S2 regions gave glycine potencies similar to those seen in NR2D(WT)-containing NMDARs.	Glycine	109-116	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	58-62
17962328-7	2008	However, receptors containing NR2A subunits including the NR2D S2 region or both NR2D S1 and S2 regions gave glycine potencies similar to those seen in NR2D(WT)-containing NMDARs.	Glycine	109-116	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	81-85
17962328-7	2008	However, receptors containing NR2A subunits including the NR2D S2 region or both NR2D S1 and S2 regions gave glycine potencies similar to those seen in NR2D(WT)-containing NMDARs.	Glycine	109-116	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	81-85
17962328-8	2008	In particular, two residues in the S2 region of the NR2A subunit (Lys719 and Tyr735) when mutated to the corresponding residues found in the NR2D subunit influence glycine potency.	Glycine	164-171	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	141-145
17962328-9	2008	We conclude that the variation in glycine potency is caused by interactions between the NR1 and NR2 ligand-binding domains that occur following agonist binding and which may be involved in the initial conformation changes that determine channel gating.	Glycine	34-41	nodal homolog 2 L homeolog	Xenopus laevis	96-99
16223757-11	2005	Our results suggest that GABA and glycine stimulate electrical activity and GLP-1 release from GLUTag cells by ligand-gated ion channel activation, a mechanism that might be important in responses to endogenous ligands from the enteric nervous system or dietary sources.	Glycine	34-41	glucagon	Mus musculus	76-81
21804546-2	2011	Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount of glycolytic carbon is diverted into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH).	Glycine	163-170	phosphoglycerate dehydrogenase	Homo sapiens	190-220
16316974-5	2005	Mutating the glycines at the equivalent sites to lysines also rendered weak inward rectifier Kir1.1 channels more inwardly rectifying.	Glycine	13-21	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	93-99
18680453-3	2008	In this review, we propose that glycine repeats present only in GSK3alpha may result in the different cleavage of both isoenzymes by the protease calpain, a cleavage that modifies GSK3 activity.	Glycine	32-39	glycogen synthase kinase 3 alpha	Homo sapiens	64-73
21804546-2	2011	Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount of glycolytic carbon is diverted into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH).	Glycine	163-170	phosphoglycerate dehydrogenase	Homo sapiens	222-227
21559489-6	2011	Our studies revealed that both LANA proteins contain an N-terminal arginine/glycine (RG)-rich domain spanning a conserved chromatin-binding motif, which binds directly to importin beta1 in a RanGTP-sensitive manner and serves as an NLS in the importin beta1-mediated non-classical nuclear import pathway.	Glycine	76-83	LANA	Human gammaherpesvirus 8	31-35
17978471-4	2007	Treatment with glycine (1-16 mM) for 72 h inhibited alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenesis in a concentration-dependent manner without any effects on cell proliferation in B16F0 melanoma cells.	Glycine	15-22	pro-opiomelanocortin-alpha	Mus musculus	52-88
16325708-8	2005	The beta1-AR genotype was determined by polymerase chain reaction with restriction fragment length polymorphisms at codons 49 (serine [Ser] or glycine [Gly]) and 389 (arginine [Arg] or Gly).	Glycine	143-150	adrenoceptor beta 1	Homo sapiens	4-12
16325708-8	2005	The beta1-AR genotype was determined by polymerase chain reaction with restriction fragment length polymorphisms at codons 49 (serine [Ser] or glycine [Gly]) and 389 (arginine [Arg] or Gly).	Glycine	152-155	adrenoceptor beta 1	Homo sapiens	4-12
16325708-8	2005	The beta1-AR genotype was determined by polymerase chain reaction with restriction fragment length polymorphisms at codons 49 (serine [Ser] or glycine [Gly]) and 389 (arginine [Arg] or Gly).	Glycine	185-188	adrenoceptor beta 1	Homo sapiens	4-12
17978471-4	2007	Treatment with glycine (1-16 mM) for 72 h inhibited alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenesis in a concentration-dependent manner without any effects on cell proliferation in B16F0 melanoma cells.	Glycine	15-22	pro-opiomelanocortin-alpha	Mus musculus	90-99
17978471-6	2007	The highest dose of glycine inhibited the alpha-MSH-induced increment of tyrosinase protein levels in B16F0 melanoma cells.	Glycine	20-27	pro-opiomelanocortin-alpha	Mus musculus	42-51
21486482-12	2011	Deletion of the glycine-rich C-terminal region, which contains a nuclear localization sequence, caused a substantial level of retention of the other MSL proteins in the cytoplasm.	Glycine	16-23	male-specific lethal 3	Drosophila melanogaster	149-152
17613527-8	2007	Consistent with these data, the introduction of glycine in the analogous position of C-RAF (S339G mutant) led to a constitutively active C-RAF kinase.	Glycine	48-55	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	85-90
17613527-8	2007	Consistent with these data, the introduction of glycine in the analogous position of C-RAF (S339G mutant) led to a constitutively active C-RAF kinase.	Glycine	48-55	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	137-142
21466672-1	2011	BACKGROUND: Hemoglobin A2" (delta 16 Gly   Arg) is globally the commonest delta chain variant of HbA2.	Glycine	37-40	hemoglobin subunit alpha 2	Homo sapiens	97-101
17618650-5	2007	Substituting the alpha-helical motif (residues 9-35) with a short Gly-Gly-Ser-Gly linker dramatically affects the protein stability such that under physiological conditions the mutant (Deltaalpha-ILBP) is highly disordered.	Glycine	66-69	gastrotropin	Oryctolagus cuniculus	196-200
17618650-5	2007	Substituting the alpha-helical motif (residues 9-35) with a short Gly-Gly-Ser-Gly linker dramatically affects the protein stability such that under physiological conditions the mutant (Deltaalpha-ILBP) is highly disordered.	Glycine	70-73	gastrotropin	Oryctolagus cuniculus	196-200
17618650-5	2007	Substituting the alpha-helical motif (residues 9-35) with a short Gly-Gly-Ser-Gly linker dramatically affects the protein stability such that under physiological conditions the mutant (Deltaalpha-ILBP) is highly disordered.	Glycine	70-73	gastrotropin	Oryctolagus cuniculus	196-200
16139803-5	2005	Treatment with taurine and glycine conjugates of lithocholic and deoxycholic acids stimulated reversible activation of the p44/42 MAP kinase signaling cascade and proliferation of H508 cells.	Glycine	27-34	interferon induced protein 44	Homo sapiens	123-126
16115813-7	2005	We present data showing that the MBL1P1 gene has been repeatedly hit throughout evolution and silenced eventually by mutations in the glycine residues of the collagen-like region.	Glycine	134-141	mannose binding lectin 1, pseudogene	Homo sapiens	33-39
16121195-2	2005	It catalyzes the synthesis of 5-aminolevulinic acid, the first common precursor of all tetrapyrroles, from glycine and succinyl-coenzyme A (sCoA) in a pyridoxal 5"-phosphate (PLP)-dependent manner.	Glycine	107-114	pyridoxal phosphatase	Homo sapiens	175-178
21122942-4	2011	Our results indicated that growing the ATP-depleted MDCK cells in glycine-containing media increased the level of phosphorylated extracellular signal-regulated kinase 1 and 2 (ERK1/2), Ets-like transcription factor-1 (Elk1), AKT, and Forkhead box O-class 1 (FoxO1), decreased the level of phosphorylated p38 mitogen-activated protein kinase, while having little effect on the phosphorylation status of c-Jun N-terminal kinase 1 and 2.	Glycine	66-73	ETS transcription factor ELK1	Canis lupus familiaris	185-216
21122942-4	2011	Our results indicated that growing the ATP-depleted MDCK cells in glycine-containing media increased the level of phosphorylated extracellular signal-regulated kinase 1 and 2 (ERK1/2), Ets-like transcription factor-1 (Elk1), AKT, and Forkhead box O-class 1 (FoxO1), decreased the level of phosphorylated p38 mitogen-activated protein kinase, while having little effect on the phosphorylation status of c-Jun N-terminal kinase 1 and 2.	Glycine	66-73	ETS transcription factor ELK1	Canis lupus familiaris	218-222
21153865-6	2011	h[Gly(2)]GLP-2 pretreatment prevented the TNF-alpha/Act D-induced oxidative injury by a significant reduction in the intestinal injury, apoptotic index, expression of active caspase-3, lipid peroxidation and GSH levels, GPx and SOD activities; a markedly increase in cell proliferation, and CAT activity.	Glycine	2-5	glucagon-like peptide 2 receptor	Mus musculus	9-14
16142915-9	2005	We use this continuous assay to analyze catalysis by wild-type human PDI and a variant in which the C-terminal cysteine residue within each Cys-Gly-His-Cys active site is replaced with alanine.	Glycine	144-147	prolyl 4-hydroxylase subunit beta	Homo sapiens	69-72
21233494-10	2011	Possibly, CO(2) acidification modulates a pH-sensitive loop on the NMDA receptor that in turn alters glycine binding affinity on the GluN1 subunit.	Glycine	101-108	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	133-138
15955813-2	2005	Herein we show that the Tudor domains of the spinal muscular atrophy gene product SMN, the splicing factor 30 kDa (SPF30), and the Tudor domain-containing 3 (TDRD3) proteins interacted with arginine-glycine-rich motifs in a methylarginine-dependent manner.	Glycine	199-206	survival motor neuron domain containing 1	Homo sapiens	91-113
15955813-2	2005	Herein we show that the Tudor domains of the spinal muscular atrophy gene product SMN, the splicing factor 30 kDa (SPF30), and the Tudor domain-containing 3 (TDRD3) proteins interacted with arginine-glycine-rich motifs in a methylarginine-dependent manner.	Glycine	199-206	survival motor neuron domain containing 1	Homo sapiens	115-120
21138844-14	2011	A glycine and two positively charged residues are conserved in most parvulin proteins in this flexible loop region, which may be of general functional importance for parvulin-type PPIases.	Glycine	2-9	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	Homo sapiens	68-76
15908697-0	2005	Gly-103 in the N-terminal domain of Saccharomyces cerevisiae Rad51 protein is critical for DNA binding.	Glycine	0-3	recombinase RAD51	Saccharomyces cerevisiae S288C	61-66
15908697-4	2005	Here we show that glycine 103 in the N-terminal domain of Saccharomyces cerevisiae Rad51 is important for binding to single-stranded and duplex DNA.	Glycine	18-25	recombinase RAD51	Saccharomyces cerevisiae S288C	83-88
15996549-3	2005	Whereas ACPC and ACBC partially activate the NMDA receptor by 80% and 42%, respectively, their cocrystal structures of the NR1 ligand binding core show the same degree of domain closure as found in the complex with glycine, a full agonist, illustrating that the NR1 subunit provides a new paradigm for partial agonist action that is distinct from that of the evolutionarily related GluR2, AMPA-sensitive receptor.	Glycine	215-222	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	382-387
21138844-14	2011	A glycine and two positively charged residues are conserved in most parvulin proteins in this flexible loop region, which may be of general functional importance for parvulin-type PPIases.	Glycine	2-9	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	Homo sapiens	166-174
21209336-1	2011	The ubiquitin (Ub)-related modifier Urm1 functions as a sulfur carrier in tRNA thiolation by means of a mechanism that requires the formation of a thiocarboxylate at the C-terminal glycine residue of Urm1.	Glycine	181-188	ubiquitin related modifier 1	Homo sapiens	36-40
15968466-3	2005	The Na+-dependent (NHE3-sensitive) component of apical dipeptide ([14C] Gly-Sar) uptake was inhibited by the selective NHE inhibitors with the same order of potency observed for inhibition of apical 22Na+ uptake.	Glycine	72-75	solute carrier family 9 member C1	Homo sapiens	19-22
15948949-4	2005	Loss of BAS1 abolished or significantly reduced the repression of these genes in response to glycine removal but this phenotype was much less apparent in the absence of BAS2 or GCN4.	Glycine	93-100	Bas1p	Saccharomyces cerevisiae S288C	8-12
21209336-1	2011	The ubiquitin (Ub)-related modifier Urm1 functions as a sulfur carrier in tRNA thiolation by means of a mechanism that requires the formation of a thiocarboxylate at the C-terminal glycine residue of Urm1.	Glycine	181-188	ubiquitin related modifier 1	Homo sapiens	200-204
22071264-8	2011	These observations led to the discovery that mouse ES cells use the threonine dehydrogenase (TDH) enzyme to convert threonine into acetyl-coenzyme A and glycine, thereby facilitating consumption of threonine as a metabolic fuel.	Glycine	153-160	L-threonine dehydrogenase	Mus musculus	68-91
15948949-5	2005	Addition of a Bas1p-LexA fusion protein to a strain with a LexAop-LacZ fusion showed a strong glycine effect both in a BAS2 and a bas2 background.	Glycine	94-101	Bas1p	Saccharomyces cerevisiae S288C	14-19
15948949-6	2005	A Bas1p-VP16 fusion protein activated expression in a bas1bas2 strain but no glycine effect was observed while a Bas1p-Bas2p fusion protein activated expression to a lesser extent with a slight stimulation by glycine.	Glycine	209-216	Bas1p	Saccharomyces cerevisiae S288C	113-118
15948949-7	2005	These results suggest that glycine affects Bas1p activation of transcription rather than DNA binding and that Bas2p is not required for this affect.	Glycine	27-34	Bas1p	Saccharomyces cerevisiae S288C	43-48
22071264-8	2011	These observations led to the discovery that mouse ES cells use the threonine dehydrogenase (TDH) enzyme to convert threonine into acetyl-coenzyme A and glycine, thereby facilitating consumption of threonine as a metabolic fuel.	Glycine	153-160	L-threonine dehydrogenase	Mus musculus	93-96
15948949-8	2005	Glycine withdrawal repressed many of the same genes as addition of adenine, a process known to be dependent on Bas1p.	Glycine	0-7	Bas1p	Saccharomyces cerevisiae S288C	111-116
21417576-2	2011	Sequencing of the amplified alpha2-globin gene revealed a 9 nucleotide (nt) deletion (-C GAG TAT GG) at codons 22-25, which results in a predicted alpha-globin chain that is missing amino acid residues 23-25 (Glu-Tyr-Gly) and the formation of Hb Zhanjiang.	Glycine	217-220	hemoglobin subunit alpha 2	Homo sapiens	28-41
15948949-13	2005	A number of genes, including BAS1 were required for activation by glycine but only the SHM2 gene was required for repression in the absence of glycine.	Glycine	66-73	Bas1p	Saccharomyces cerevisiae S288C	29-33
15948949-14	2005	We also showed that regulation of the SHM2 promoter by glycine requires Bas1p but not Bas2p or Gcn4p using a beta-galactosidase reporter.	Glycine	55-62	Bas1p	Saccharomyces cerevisiae S288C	72-77
21088147-5	2011	They describe the development and evaluation of a simple noninvasive fluorescence assay for measuring DPP1 activity in fresh or cryopreserved human THP-1 cells using the substrate H-Gly-Phe-AFC (amino-fluoro-coumarin).	Glycine	180-185	cathepsin C	Homo sapiens	102-106
15973048-1	2005	The Saccharomyces cerevisiae Put4 permease is significant for the transport of proline, alanine, and glycine.	Glycine	101-108	proline permease PUT4	Saccharomyces cerevisiae S288C	29-33
15981099-3	2005	We further determined the allelic status of the fibroblastic growth factor receptor 4 (FGFR4) gene at position 388 (arginine [Arg(388)] or glycine [Gly(388)]) in eighteen GC patients, because the presence of at least one Arg(388) allele has been suggested to favor tumor cell motility compared to tumor cells homozygeous for the Gly(388) allele.	Glycine	148-151	fibroblast growth factor receptor 4	Homo sapiens	48-85
15981099-3	2005	We further determined the allelic status of the fibroblastic growth factor receptor 4 (FGFR4) gene at position 388 (arginine [Arg(388)] or glycine [Gly(388)]) in eighteen GC patients, because the presence of at least one Arg(388) allele has been suggested to favor tumor cell motility compared to tumor cells homozygeous for the Gly(388) allele.	Glycine	148-151	fibroblast growth factor receptor 4	Homo sapiens	87-92
22194882-3	2011	In the amidation reaction, the reactant (glycine-extended peptide) is converted into a reaction intermediate (hydroxyglycine-extended peptide) by the copper-dependent peptidylglycine-alpha-hydroxylating monooxygenase (PHM) domain of PAM.	Glycine	41-48	peptidylglycine alpha-amidating monooxygenase	Mus musculus	167-216
15981099-3	2005	We further determined the allelic status of the fibroblastic growth factor receptor 4 (FGFR4) gene at position 388 (arginine [Arg(388)] or glycine [Gly(388)]) in eighteen GC patients, because the presence of at least one Arg(388) allele has been suggested to favor tumor cell motility compared to tumor cells homozygeous for the Gly(388) allele.	Glycine	329-332	fibroblast growth factor receptor 4	Homo sapiens	48-85
15981099-3	2005	We further determined the allelic status of the fibroblastic growth factor receptor 4 (FGFR4) gene at position 388 (arginine [Arg(388)] or glycine [Gly(388)]) in eighteen GC patients, because the presence of at least one Arg(388) allele has been suggested to favor tumor cell motility compared to tumor cells homozygeous for the Gly(388) allele.	Glycine	329-332	fibroblast growth factor receptor 4	Homo sapiens	87-92
22194882-3	2011	In the amidation reaction, the reactant (glycine-extended peptide) is converted into a reaction intermediate (hydroxyglycine-extended peptide) by the copper-dependent peptidylglycine-alpha-hydroxylating monooxygenase (PHM) domain of PAM.	Glycine	41-48	peptidylglycine alpha-amidating monooxygenase	Mus musculus	218-221
22194882-3	2011	In the amidation reaction, the reactant (glycine-extended peptide) is converted into a reaction intermediate (hydroxyglycine-extended peptide) by the copper-dependent peptidylglycine-alpha-hydroxylating monooxygenase (PHM) domain of PAM.	Glycine	41-48	peptidylglycine alpha-amidating monooxygenase	Mus musculus	233-236
22073143-3	2011	We uncover a novel pathway for ATP generation that involves reactions from serine biosynthesis, one-carbon metabolism and the glycine cleavage system, and show that the pathway is transcriptionally upregulated in an inducible murine model of Myc-driven liver tumorigenesis.	Glycine	126-133	myelocytomatosis oncogene	Mus musculus	242-245
15862300-5	2005	Yeast two-hybrid assays further indicated in vivo that such binding relates to the fragment (aa 161-210) of SARS_N and the Gly-rich domain (aa 203-320) of hnRNP A1.	Glycine	123-126	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	155-163
21949857-5	2011	The number of Fos-positive orexin neurons markedly decreased after intraperitoneal administration of glycine to mice.	Glycine	101-108	hypocretin	Mus musculus	27-33
15851735-0	2005	Mild glycine encephalopathy (NKH) in a large kindred due to a silent exonic GLDC splice mutation.	Glycine	5-12	glycine decarboxylase	Homo sapiens	76-80
15851735-15	2005	The 4 to 6% of normally spliced GLDC mRNA in the patients may account for their relatively favorable clinical outcome compared with patients with classic glycine encephalopathy.	Glycine	154-161	glycine decarboxylase	Homo sapiens	32-36
21949857-7	2011	Glycine directly induced hyperpolarization and cessation of firing of orexin neurons.	Glycine	0-7	hypocretin	Mus musculus	70-76
20958962-4	2010	The recently discovered NR3 subunits feature an unprecedented glycine-arginine combination at those critical sites within the pore.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	24-27
15680477-1	2005	The hexapeptide Thr-Gly-Glu-Asn-His-Arg (HLDF-6), which was first identified as an active fragment of the human leukemia differentiation factor (HLDF) molecule, displays differentiation-inducing, neuroprotective and anti-drug abuse activities.	Glycine	20-23	ribosomal protein S21	Homo sapiens	41-45
15680477-1	2005	The hexapeptide Thr-Gly-Glu-Asn-His-Arg (HLDF-6), which was first identified as an active fragment of the human leukemia differentiation factor (HLDF) molecule, displays differentiation-inducing, neuroprotective and anti-drug abuse activities.	Glycine	20-23	ribosomal protein S21	Homo sapiens	106-143
15680477-1	2005	The hexapeptide Thr-Gly-Glu-Asn-His-Arg (HLDF-6), which was first identified as an active fragment of the human leukemia differentiation factor (HLDF) molecule, displays differentiation-inducing, neuroprotective and anti-drug abuse activities.	Glycine	20-23	ribosomal protein S21	Homo sapiens	145-149
20958962-8	2010	Ca2+ permeability could be rescued by mutating the NR3 N site glycine to the NR1-like asparagine.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	51-54
20939880-7	2010	RESULTS: The minimum surface roughening was obtained by air-polishing with glycine powder for 5 s, at either of the considered distances, which resulted in a mean roughness of ~300 nm on a 30 x 30 mum2 surface area, whereas in the other cases it was in the range of 400-750 nm.	Glycine	75-82	trafficking protein particle complex subunit 1	Homo sapiens	197-201
15490133-3	2005	Purely excitatory glycine receptors composed of NR1 and NR3/NR4 NMDA receptor subunits have recently been described, raising the possibility of excitotoxic effects mediated by glycine alone.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	56-59
19864106-8	2010	Glycine clearly increased fat tissue PPAR-gamma expression in lean but not in MSG/Ob mice.	Glycine	0-7	peroxisome proliferator activated receptor gamma	Mus musculus	37-47
19864106-11	2010	In conclusion, glycine regulates the production of inflammatory cytokines through PPAR-gamma.	Glycine	15-22	peroxisome proliferator activated receptor gamma	Mus musculus	82-92
20660043-9	2010	RESULTS: Homozygosis for FGFR4 glycine (Gly(388)) allele was associated with reduced disease-free survival, in the univariate analysis (hazard ratio of 6.91; 95% confidence interval of 1.14-11.26; P = 0.028).	Glycine	31-38	fibroblast growth factor receptor 4	Homo sapiens	25-30
15542598-10	2005	When tau was phosphorylated by glycogen synthase kinase-3beta, most of these proteolytic processes were inhibited, except for the first cleavage at the Arg(155)-Gly(156) bond.	Glycine	161-164	glycogen synthase kinase 3 beta	Homo sapiens	31-61
20660043-9	2010	RESULTS: Homozygosis for FGFR4 glycine (Gly(388)) allele was associated with reduced disease-free survival, in the univariate analysis (hazard ratio of 6.91; 95% confidence interval of 1.14-11.26; P = 0.028).	Glycine	40-43	fibroblast growth factor receptor 4	Homo sapiens	25-30
20660043-12	2010	CONCLUSIONS: Our data suggest that homozygosis for FGFR4 Gly(388) allele and FGFR4 overexpression are associated with higher frequency of postoperative recurrence and persistence of Cushing"s disease, respectively.	Glycine	57-60	fibroblast growth factor receptor 4	Homo sapiens	51-56
15639231-2	2005	Here we report the cloning, purification, and characterization of the C-terminal glycine/arginine-rich (GAR) domain of pea nucleolin.	Glycine	81-88	nucleolin	Homo sapiens	123-132
17592518-5	2007	KEY RESULTS: The mGluR1/5 agonist 3,5-DHPG, inactive on its own, potentiated both the release of [(3)H]noradrenaline elicited by AMPA/NMDA/glycine and that evoked by NMDA/glycine following Mg(2+) removal.	Glycine	139-146	glutamate metabotropic receptor 1	Homo sapiens	17-23
17592518-5	2007	KEY RESULTS: The mGluR1/5 agonist 3,5-DHPG, inactive on its own, potentiated both the release of [(3)H]noradrenaline elicited by AMPA/NMDA/glycine and that evoked by NMDA/glycine following Mg(2+) removal.	Glycine	171-178	glutamate metabotropic receptor 1	Homo sapiens	17-23
20626561-2	2010	We now report the effects of the arginine-glycine-aspartic acid (RGD)-containing peptide fragment of OPN and OPN inactivation on the survival of tyrosine hydroxylase (TH) positive neurones in primary rat ventral mesencephalic (VM) cultures and in SN in the rat.	Glycine	42-49	secreted phosphoprotein 1	Rattus norvegicus	101-104
17592518-6	2007	The effect of 3,5-DHPG on the AMPA/NMDA/glycine-induced release was insensitive to the mGluR1 antagonist CPCCOEt, but it was abolished by the mGluR5 antagonist MPEP; moreover, it was potentiated by the mGluR5 positive allosteric modulator DFB.	Glycine	40-47	glutamate metabotropic receptor 1	Homo sapiens	87-93
17592518-6	2007	The effect of 3,5-DHPG on the AMPA/NMDA/glycine-induced release was insensitive to the mGluR1 antagonist CPCCOEt, but it was abolished by the mGluR5 antagonist MPEP; moreover, it was potentiated by the mGluR5 positive allosteric modulator DFB.	Glycine	40-47	glutamate receptor, ionotropic, kainate 1	Mus musculus	142-148
17592518-6	2007	The effect of 3,5-DHPG on the AMPA/NMDA/glycine-induced release was insensitive to the mGluR1 antagonist CPCCOEt, but it was abolished by the mGluR5 antagonist MPEP; moreover, it was potentiated by the mGluR5 positive allosteric modulator DFB.	Glycine	40-47	glutamate receptor, ionotropic, kainate 1	Mus musculus	202-208
17555723-7	2007	The results suggest the existence of the following K+ channel subtypes on glycinergic nerve endings that are involved in regulating "spontaneous" glycine release (mIPSCs): the Shaker-related K+ channels Kv1.1, Kv1.2, Kv1.3, Kv1.6 and Kv1.7 and the intracellular Ca2+ -sensitive K+ channels BKCa, IKCa and SKCa.	Glycine	74-81	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	290-294
15716133-1	2005	Cicer arietinum GRP1 and GRP2 are rich in glycine interposed with histidine and tyrosine.	Glycine	42-49	glycine-rich cell wall structural protein	Cicer arietinum	16-20
15716133-1	2005	Cicer arietinum GRP1 and GRP2 are rich in glycine interposed with histidine and tyrosine.	Glycine	42-49	glycine-rich protein 2	Cicer arietinum	25-29
20471398-7	2010	In addition, we observe similar results when cis-P114 is mutated to glycine in a homologous RNase, human pancreatic RNase 1.	Glycine	68-75	ribonuclease A family member 1, pancreatic	Homo sapiens	116-123
15456797-12	2005	Although gramicidin perforated-patch recordings revealed that GABA or glycine depolarized P5-P7 cells but hyperpolarized P14-P15 cells, the young depolarizing inputs were not suprathreshold.	Glycine	70-77	S100 calcium binding protein A9	Rattus norvegicus	121-124
20527984-5	2010	The expression level of vascular endothelial growth factor (VEGF) of HUVEC was significantly decreased by 1.5 and 2.0 mg/mL of GLY extract.	Glycine	127-130	vascular endothelial growth factor A	Gallus gallus	24-58
15670722-2	2005	The majority of cases are caused by mutations in the P-protein, one of the four components of the glycine cleavage enzyme, also known as glycine decarboxylase (GLDC).	Glycine	98-105	OCA2 melanosomal transmembrane protein	Homo sapiens	53-62
15670722-2	2005	The majority of cases are caused by mutations in the P-protein, one of the four components of the glycine cleavage enzyme, also known as glycine decarboxylase (GLDC).	Glycine	98-105	glycine decarboxylase	Homo sapiens	137-158
15670722-2	2005	The majority of cases are caused by mutations in the P-protein, one of the four components of the glycine cleavage enzyme, also known as glycine decarboxylase (GLDC).	Glycine	98-105	glycine decarboxylase	Homo sapiens	160-164
17331559-5	2007	Insertion of a peptide linker Ser-Gly-Gly-Ser-Gly at either side of the apelin motif in one of the chimeric envelopes resulted in an ability of the chimeric envelope to bind to and infect cells through APJ although with low efficiency.	Glycine	34-37	apelin receptor	Homo sapiens	202-205
17331559-5	2007	Insertion of a peptide linker Ser-Gly-Gly-Ser-Gly at either side of the apelin motif in one of the chimeric envelopes resulted in an ability of the chimeric envelope to bind to and infect cells through APJ although with low efficiency.	Glycine	38-41	apelin receptor	Homo sapiens	202-205
17331559-5	2007	Insertion of a peptide linker Ser-Gly-Gly-Ser-Gly at either side of the apelin motif in one of the chimeric envelopes resulted in an ability of the chimeric envelope to bind to and infect cells through APJ although with low efficiency.	Glycine	38-41	apelin receptor	Homo sapiens	202-205
17554807-8	2007	These results indicate that Gly-Pro-Hyp can be partially hydrolyzed by the brush-border membrane-bound aminopeptidase N to remove Gly, and that the resulting Pro-Hyp is, in part, transported into the small intestinal epithelial cells via the H+-coupled PEPT1.	Glycine	28-31	alanyl aminopeptidase, membrane	Homo sapiens	103-119
17554807-8	2007	These results indicate that Gly-Pro-Hyp can be partially hydrolyzed by the brush-border membrane-bound aminopeptidase N to remove Gly, and that the resulting Pro-Hyp is, in part, transported into the small intestinal epithelial cells via the H+-coupled PEPT1.	Glycine	130-133	alanyl aminopeptidase, membrane	Homo sapiens	103-119
20527984-5	2010	The expression level of vascular endothelial growth factor (VEGF) of HUVEC was significantly decreased by 1.5 and 2.0 mg/mL of GLY extract.	Glycine	127-130	vascular endothelial growth factor A	Gallus gallus	60-64
20527984-8	2010	These observations suggested that GLY extract has an inhibitory effect on angiogenesis, which in turn may prevent tumor growth, and its mechanism might be partially associated with blocking VEGF protein expression of HUVEC.	Glycine	34-37	vascular endothelial growth factor A	Gallus gallus	190-194
20303335-4	2010	Solid-phase synthesis of cRGDyK (Arg-Gly-Asp-(D)Tyr-Lys) peptide and FAM-conjugated peptide were employed for binding to integrin alpha v beta 3.	Glycine	37-40	integrin subunit alpha V	Rattus norvegicus	121-137
15642343-0	2005	A Gly/Ala switch contributes to high affinity binding of benzoxazinone-based non-peptide oxytocin receptor antagonists.	Glycine	2-5	oxytocin receptor	Homo sapiens	89-106
20410266-3	2010	This was shown not to be due to an antigenic change in hemagglutinin (HA) but was shown to be the result of a mutation in aspartic acid 151 of neuraminidase (NA) to glycine, asparagine, or alanine, which caused an oseltamivir-sensitive agglutination of RBCs.	Glycine	165-172	neuraminidase 1	Homo sapiens	143-156
20410266-3	2010	This was shown not to be due to an antigenic change in hemagglutinin (HA) but was shown to be the result of a mutation in aspartic acid 151 of neuraminidase (NA) to glycine, asparagine, or alanine, which caused an oseltamivir-sensitive agglutination of RBCs.	Glycine	165-172	neuraminidase 1	Homo sapiens	158-160
15665496-2	2005	Previously we found that the substitution of the 74th amino acid from glycine to cysteine in Ypd1 yields a mutant resistant to pradimicin.	Glycine	70-77	Ypd1p	Saccharomyces cerevisiae S288C	93-97
20394787-5	2010	We also observed that the activity of the mitochondrial enzyme citrate synthase was markedly inhibited by glycine, whereas the other activities of the citric acid cycle were not altered.	Glycine	106-113	citrate synthase	Homo sapiens	63-79
15864413-5	2005	A methionine to threonine change in the initiation codon of the glycine decarboxylase gene led to markedly reduced glycine decarboxylase mRNA levels and abolished glycine cleavage system activity.	Glycine	64-71	glycine decarboxylase	Homo sapiens	115-136
20394362-4	2010	First, succinyl-CoA and glycine are condensed to generate 5-aminolevulinate (ALA) by a dedicated PLP-dependent ALA synthase (ORF34).	Glycine	24-31	hypothetical protein	Escherichia coli	125-130
15385531-13	2004	The tail region of K10 is composed largely of quasi-repeats of Tyr-(Gly/Ser)n. A synthetic peptide corresponding to a typical glycine loop (YGGGSSGGGSSGGY; Y-Y loop peptide) inhibited the adherence of S. aureus ClfB+ to immobilized MK10 to a level of 80%, whereas control peptides had no effect.	Glycine	68-71	keratin 10	Mus musculus	19-22
15385531-13	2004	The tail region of K10 is composed largely of quasi-repeats of Tyr-(Gly/Ser)n. A synthetic peptide corresponding to a typical glycine loop (YGGGSSGGGSSGGY; Y-Y loop peptide) inhibited the adherence of S. aureus ClfB+ to immobilized MK10 to a level of 80%, whereas control peptides had no effect.	Glycine	126-133	keratin 10	Mus musculus	19-22
15374578-5	2004	Typical antipsychotics haloperidol, thioridazine and chlorpromazine non-selectively inhibited [(14)C]glycine uptake mediated by GlyT1a and GlyT2 with potency of 9-21 microM.	Glycine	101-108	solute carrier family 6 member 5	Homo sapiens	139-144
20150244-9	2010	In contrast, epithelial acidification and reduced I(sc) response to Gly-Sar exposure occurred during pharmacological inhibition of Cl(-)/HCO(3)(-) exchange and in the Pat-1(-) intestine.	Glycine	68-71	solute carrier family 26, member 6	Mus musculus	167-172
20150244-10	2010	Pat-1 interacts with carbonic anhydrase II (CAII), and studies using CAII(-) intestine or the pharmacological inhibitor methazolamide on WT intestine resulted in increased epithelial acidification during Gly-Sar exposure.	Glycine	204-207	solute carrier family 26, member 6	Mus musculus	0-5
20150244-12	2010	Measurement of Cl(-)/HCO(3)(-) exchange in the presence of Gly-Sar revealed an increased rate of Cl(-)(OUT)/HCO(3)(-)(IN) exchange that was both Pat-1 dependent and CA dependent.	Glycine	59-62	solute carrier family 26, member 6	Mus musculus	145-150
15543539-2	2004	The single Ser/Gly difference between CaCNT/19-20196 and CaCNT occurs at position 328 in putative TM 7, and corresponds to a Ser/Gly substitution previously shown to contribute to the contrasting pyrimidine and purine nucleoside selectivities of human (h) and rat (r) Na+-dependent CNT1 and CNT2.	Glycine	15-18	solute carrier family 28 member 2	Rattus norvegicus	291-295
20067760-8	2010	On the other hand, G579E showed a slower voltage-dependent current inactivation (VDI) compared to Ca(v)1.2, although G579Q showed a normal VDI, implying that Gly(579) in domain II is involved in the regulation of VDI and that the incorporation of a negative charge alters the VDI kinetics.	Glycine	158-161	immunoglobulin lambda variable 2-8	Homo sapiens	98-106
15543539-2	2004	The single Ser/Gly difference between CaCNT/19-20196 and CaCNT occurs at position 328 in putative TM 7, and corresponds to a Ser/Gly substitution previously shown to contribute to the contrasting pyrimidine and purine nucleoside selectivities of human (h) and rat (r) Na+-dependent CNT1 and CNT2.	Glycine	129-132	solute carrier family 28 member 2	Rattus norvegicus	291-295
20412299-8	2010	Structural comparison with the nNOS-DYNLL1 complex reveals that a glycine residue of GRINL1A occupies the conserved glutamine site within the DYNLL1 binding groove.	Glycine	66-73	nitric oxide synthase 1	Homo sapiens	31-35
20412299-8	2010	Structural comparison with the nNOS-DYNLL1 complex reveals that a glycine residue of GRINL1A occupies the conserved glutamine site within the DYNLL1 binding groove.	Glycine	66-73	GCOM1, MYZAP-POLR2M combined locus	Homo sapiens	85-92
20948559-3	2010	Only the Arg389Gly polymorphism of the beta(1)-adrenergic receptor gene was associated with increased risk for mild OSA in hypertensive patients (Arg/Arg versus Gly/Arg/Gly/Gly, 2.1, 95% CI, 1.02-4.7).	Glycine	15-18	adrenoceptor beta 1	Homo sapiens	39-66
15272001-14	2004	The mls seedlings also accumulate more glycine and serine than icl or wild type seedlings, consistent with a diversion of glyoxylate into these intermediates of the photorespiratory pathway.	Glycine	39-46	malate synthase	Arabidopsis thaliana	4-7
15359279-2	2004	Remarkably, splice variants that differ only by the insertion of a single glycine residue in the beta1/beta2 loop exhibit dual specificity for PtdIns(3,4,5)P(3) and PtdIns(4,5)P(2).	Glycine	74-81	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	103-108
20948559-3	2010	Only the Arg389Gly polymorphism of the beta(1)-adrenergic receptor gene was associated with increased risk for mild OSA in hypertensive patients (Arg/Arg versus Gly/Arg/Gly/Gly, 2.1, 95% CI, 1.02-4.7).	Glycine	161-164	adrenoceptor beta 1	Homo sapiens	39-66
20948559-3	2010	Only the Arg389Gly polymorphism of the beta(1)-adrenergic receptor gene was associated with increased risk for mild OSA in hypertensive patients (Arg/Arg versus Gly/Arg/Gly/Gly, 2.1, 95% CI, 1.02-4.7).	Glycine	161-164	adrenoceptor beta 1	Homo sapiens	39-66
20354225-2	2010	We found that NUAK1 interacts with several myosin phosphatases, including the myosin phosphatase targeting-1 (MYPT1)-protein phosphatase-1beta (PP1beta) complex, through conserved Gly-Ile-Leu-Lys motifs that are direct binding sites for PP1beta.	Glycine	180-183	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	78-108
15262990-0	2004	CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics.	Glycine	89-96	CAP-Gly domain containing linker protein 3	Homo sapiens	0-8
15262990-0	2004	CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics.	Glycine	114-117	CAP-Gly domain containing linker protein 3	Homo sapiens	0-8
20354225-2	2010	We found that NUAK1 interacts with several myosin phosphatases, including the myosin phosphatase targeting-1 (MYPT1)-protein phosphatase-1beta (PP1beta) complex, through conserved Gly-Ile-Leu-Lys motifs that are direct binding sites for PP1beta.	Glycine	180-183	protein phosphatase 1 regulatory subunit 12A	Homo sapiens	110-115
20354225-2	2010	We found that NUAK1 interacts with several myosin phosphatases, including the myosin phosphatase targeting-1 (MYPT1)-protein phosphatase-1beta (PP1beta) complex, through conserved Gly-Ile-Leu-Lys motifs that are direct binding sites for PP1beta.	Glycine	180-183	protein phosphatase 1 catalytic subunit beta	Homo sapiens	144-151
20026029-6	2010	A potential target lysine in Syn67 was biotinylated by HCS only after arginine-to-glycine substitutions in Syn67 produced a histone-like peptide.	Glycine	82-89	holocarboxylase synthetase	Homo sapiens	55-58
15220338-6	2004	Binding studies indicated mGR (mGR437V) displayed a weaker affinity for GREs containing a thymine at the -6 position than a mGR mutant containing a glycine at residue 437 (mGR437G).	Glycine	148-155	zinc finger, BED type containing 6	Mus musculus	26-29
19616076-2	2010	Within the 15-member galectin family of proteins, Gal3 (M(r) approximately 30,000) is the sole representative of the chimera subclass in which a proline- and glycine-rich NH(2)-terminal domain is fused onto a COOH-terminal carbohydrate recognition domain responsible for binding galactose-containing glycoconjugates.	Glycine	158-165	galectin 3	Homo sapiens	50-54
15247292-0	2004	Importance of Gly-13 for the coenzyme binding of human UDP-glucose dehydrogenase.	Glycine	14-17	UDP-glucose 6-dehydrogenase	Homo sapiens	55-80
19890704-2	2010	It has recently been observed that stimulating dendrites locally with a single glutamate/glycine puff induces a local translocation of CaMKII into spines that subsequently spreads in a wave-like manner towards the distal dendritic arbor.	Glycine	89-96	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	135-141
17582333-7	2007	Long-term potentiation (LTP) induced by brief glycine application resulted in synaptic insertion of GluR1-containing AMPA receptors along with Kv4.2 internalization.	Glycine	46-53	potassium voltage-gated channel subfamily D member 2	Homo sapiens	143-148
19818814-3	2010	By using the fusion expression with unique acid labile linker Asp-Pro and biochemical purification, the three novel GHRH peptides, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys, Pro-hGHRH(1-44)-Gly-Gly-Cys, and (1)Pro-GHRH(2-44)-Gly-Gly-Cys, were obtained.	Glycine	155-158	growth hormone releasing hormone	Rattus norvegicus	116-120
19818814-3	2010	By using the fusion expression with unique acid labile linker Asp-Pro and biochemical purification, the three novel GHRH peptides, Pro-Pro-hGHRH(1-44)-Gly-Gly-Cys, Pro-hGHRH(1-44)-Gly-Gly-Cys, and (1)Pro-GHRH(2-44)-Gly-Gly-Cys, were obtained.	Glycine	155-158	growth hormone releasing hormone	Rattus norvegicus	140-144
19617589-8	2010	Mutant forms of Insig-1 and Insig-2 containing the Glu-to-Gly substitution fail to confer sterol regulation upon overexpressed Scap and reductase.	Glycine	58-61	insulin-induced gene 2 protein	Cricetulus griseus	28-35
17563362-3	2007	Notably, the p150(Glued) CAP-Gly domain that is furnished with a less positively charged surface only weakly interacts with the alpha-tubulin acidic tail.	Glycine	29-32	chromatin assembly factor 1 subunit A	Homo sapiens	13-24
21516734-5	2010	RESULTS: In patients with CHF, the Gly allele of the Gly389Arg polymorphic locus of the ADRB1 gene in homozygous state was associated with the high individual risk for CHF, the severity of its clinical manifestations and the nature of its course while carriage of the Arg allele of the Gly39Arg polymorphic locus manifested itself as a protective factor.	Glycine	35-38	adrenoceptor beta 1	Homo sapiens	88-93
17368484-2	2007	Each of them has a typical active site Cys-X-X-Cys sequence motif, the hallmark of thioredoxin being Trp-Cys-Gly-Pro-Cys.	Glycine	109-112	AT695_RS07555	Staphylococcus aureus	83-94
21516734-6	2010	During long-term carvedilol therapy, CHF patients with the Arg/Arg genotype of the ADRB1 gene were observed to have a more pronounced decrease in the functional class of heart failure, a significant increase in left ventricular ejection, and a decrease in left ventricular end-systolic and end-diastolic sizes as compared with patients with the Gly/Arg genotype.	Glycine	345-348	adrenoceptor beta 1	Homo sapiens	83-88
19726695-0	2009	Expression of glycine-activated diheteromeric NR1/NR3 receptors in human embryonic kidney 293 cells Is NR1 splice variant-dependent.	Glycine	14-21	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	50-53
19726695-1	2009	In oocytes, glycine activates receptors formed by diheteromeric combinations of N-methyl-d-aspartate (NMDA) NR1 and NR3 subunits.	Glycine	12-19	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	116-119
17417949-5	2007	To increase cell survival, arginine-glycine-aspartic acid-serine (RGDS) was incorporated into gels using a novel mixed-mode thiol-ene reaction by synthesizing a cysteine-cysteine-arginine-glycine-aspartic acid-serine-cysteine-cysteine-glycine, N-terminus to C-terminus peptide sequence with pendant cysteine residues.	Glycine	36-43	ral guanine nucleotide dissociation stimulator	Homo sapiens	66-70
19932356-1	2009	BACKGROUND: Some studies suggest that patients with asthma who are homozygous for arginine at the 16th amino acid position of the beta2-adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting beta2 agonists and inhaled corticosteroids than do those homozygous for glycine (B16 Gly/Gly).	Glycine	286-293	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	130-135
17398095-3	2007	ARNO and its three relatives, cytohesin-1, Grp1/cytohesin-3, and cytohesin-4, are expressed as two splice variants, with either two or three glycines in a loop in the phosphoinositide-binding pocket of the PH domain [5, 6].	Glycine	141-149	cytohesin 4	Homo sapiens	65-76
19932356-1	2009	BACKGROUND: Some studies suggest that patients with asthma who are homozygous for arginine at the 16th amino acid position of the beta2-adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting beta2 agonists and inhaled corticosteroids than do those homozygous for glycine (B16 Gly/Gly).	Glycine	299-302	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	130-135
17287963-4	2007	Cloning and sequencing of the RNR4 locus of the pso3-1 mutant revealed that its intermediate phenotype is attributable to a G --&gt; A transition at nucleotide 352, leading to replacement of glycine by arginine [G118R] in the mutant"s protein.	Glycine	191-198	ribonucleotide-diphosphate reductase subunit RNR4	Saccharomyces cerevisiae S288C	30-34
17287963-4	2007	Cloning and sequencing of the RNR4 locus of the pso3-1 mutant revealed that its intermediate phenotype is attributable to a G --&gt; A transition at nucleotide 352, leading to replacement of glycine by arginine [G118R] in the mutant"s protein.	Glycine	191-198	ribonucleotide-diphosphate reductase subunit RNR4	Saccharomyces cerevisiae S288C	48-52
19932356-1	2009	BACKGROUND: Some studies suggest that patients with asthma who are homozygous for arginine at the 16th amino acid position of the beta2-adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting beta2 agonists and inhaled corticosteroids than do those homozygous for glycine (B16 Gly/Gly).	Glycine	303-306	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	130-135
17188389-7	2007	The prevention of cell swelling by hepatocyte incubation in a hypertonic medium as well as the degradation of extracellular ATP with apyrase or the block P2 purinergic receptors with suramin reverted glycine-induced cytoprotection and inhibited Src, Pyk2 and p38 MAPK activation.	Glycine	200-207	mitogen activated protein kinase 14	Rattus norvegicus	259-262
17188389-9	2007	Such an effect was reverted by inhibiting p38 MAPK that also abolished glycine protection against Na+ overload caused by hypoxia.	Glycine	71-78	mitogen activated protein kinase 14	Rattus norvegicus	42-45
19919721-9	2009	Several Gly- and GABAAR properties also differed in SDH vs. DDH.	Glycine	8-11	serine dehydratase	Mus musculus	52-55
17188389-10	2007	CONCLUSIONS: Glycine-induced ATP release in response to a moderate hepatocyte swelling led to the autocrine stimulation of P2 receptors and to the activation of Src, Pyk2 and p38 MAPK that increased hepatocyte resistance to hypoxia by preventing Na+ influx through NHE.	Glycine	13-20	mitogen activated protein kinase 14	Rattus norvegicus	175-178
17361008-2	2007	NKH is caused by deficiency of the glycine cleavage multienzyme system with three specific components encoded by GLDC, AMT and GCSH.	Glycine	35-42	glycine decarboxylase	Homo sapiens	113-117
19919721-17	2009	CONCLUSION: Together these data show that Gly- and GABAARs with clearly differing physiological properties and cannabinoid-sensitivity contribute to fast synaptic inhibition in mouse SDH and DDH.	Glycine	42-45	serine dehydratase	Mus musculus	183-186
17361008-2	2007	NKH is caused by deficiency of the glycine cleavage multienzyme system with three specific components encoded by GLDC, AMT and GCSH.	Glycine	35-42	glycine cleavage system protein H	Homo sapiens	127-131
17361008-3	2007	Most patients are deficient of the enzymatic activity of glycine decarboxylase, which is encoded by GLDC.	Glycine	57-64	glycine decarboxylase	Homo sapiens	100-104
19696402-3	2009	Higher soluble EPCR levels were confirmed for Gly allele carriers (P&lt;0.0001).	Glycine	46-49	protein C receptor	Homo sapiens	15-19
17110428-3	2007	Here, we demonstrate that addition of OPN before IL-1beta in freshly isolated rat islets improved their glucose stimulated insulin secretion dose-dependently and inhibited IL-1beta-induced NO production in an arginine-glycine-aspartate-dependent manner.	Glycine	218-225	secreted phosphoprotein 1	Rattus norvegicus	38-41
17828807-4	2007	In this paper, we report the preparation of the N,S-ethoxycarbonyl methyl ester derivatives of GSH and glycine and their application to the measurement of (13)C/(12)C ratios at natural abundance in erythrocyte samples by gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS).	Glycine	103-110	guanylate cyclase 2C	Homo sapiens	284-288
19640775-1	2009	Studies of nonenzymatic electrophilic catalysis of carbon deprotonation of glycine show that pyridoxal 5"-phosphate (PLP) strongly enhances the carbon acidity of alpha-amino acids, but that this is not the overriding mechanistic imperative for cofactor catalysis.	Glycine	75-82	pyridoxal phosphatase	Homo sapiens	117-120
16962645-20	2007	In contrast, much higher factor V and VIII activities were maintained in the lyophilized glycine-supplemented plasma: approx.	Glycine	89-96	cytochrome c oxidase subunit 8A	Homo sapiens	38-42
19640775-2	2009	Although the fully protonated PLP-glycine iminium ion adduct exhibits an extraordinary low alpha-imino carbon acidity (pK(a)=6), the more weakly acidic zwitterionic iminium ion adduct (pK(a)=17) is selected for use in enzymatic reactions.	Glycine	34-41	pyridoxal phosphatase	Homo sapiens	30-33
19605466-0	2009	Glutamate64 to glycine substitution in G1 beta-bulge of ubiquitin impairs function and stabilizes structure of the protein.	Glycine	15-22	ubiquitin	Saccharomyces cerevisiae S288C	56-65
19587104-5	2009	A single nucleotide polymorphism in the coding region of MdACS3a results in an amino acid substitution (glycine-289 --&gt; valine) in the active site that inactivates the enzyme.	Glycine	104-111	1-aminocyclopropane-1-carboxylate synthase 7-like	Malus domestica	57-64
19570983-4	2009	LIP2 and LIP5 are required for lipoylation of all three mitochondrial target proteins: Lat1 and Kgd2, the respective E2 subunits of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, and Gcv3, the H protein of the glycine cleavage enzyme.	Glycine	225-232	putative lipoate synthase	Saccharomyces cerevisiae S288C	9-13
19657386-8	2009	However, ovine SPRN exhibited 4 missense mutations and expansion/contraction in a series of 5 tandem Ala/Gly-containing repeats R1-R5 encoding Sho"s hydrophobic domain.	Glycine	105-108	shadow of prion protein	Ovis aries	15-19
19525417-2	2009	The ADE3 gene is known to encode a crucial one-carbon regulon enzyme, tetrahydrofolate synthase, which is involved in the biosynthesis of purine and the amino acids methionine and glycine.	Glycine	180-187	tetrahydrofolate synthase	Saccharomyces cerevisiae S288C	70-95
19494039-4	2009	Aurora A residue glycine 198 (G198), mutated to asparagine to mimic the aligned asparagine 142 (N142) of Aurora B, causes Aurora A to bind the Aurora B binding partner INCENP but not the Aurora A binding partner TPX2.	Glycine	17-24	aurora kinase A	Homo sapiens	0-8
19494039-4	2009	Aurora A residue glycine 198 (G198), mutated to asparagine to mimic the aligned asparagine 142 (N142) of Aurora B, causes Aurora A to bind the Aurora B binding partner INCENP but not the Aurora A binding partner TPX2.	Glycine	17-24	aurora kinase A	Homo sapiens	122-130
19494039-4	2009	Aurora A residue glycine 198 (G198), mutated to asparagine to mimic the aligned asparagine 142 (N142) of Aurora B, causes Aurora A to bind the Aurora B binding partner INCENP but not the Aurora A binding partner TPX2.	Glycine	17-24	aurora kinase A	Homo sapiens	122-130
19589965-3	2009	TDH-mediated catabolism of threonine takes place in mitochondria to generate glycine and acetyl-coenzyme A (CoA), with glycine facilitating one-carbon metabolism via the glycine cleavage system and acetyl-CoA feeding the tricarboxylic acid cycle.	Glycine	77-84	L-threonine dehydrogenase	Mus musculus	0-3
19589965-3	2009	TDH-mediated catabolism of threonine takes place in mitochondria to generate glycine and acetyl-coenzyme A (CoA), with glycine facilitating one-carbon metabolism via the glycine cleavage system and acetyl-CoA feeding the tricarboxylic acid cycle.	Glycine	119-126	L-threonine dehydrogenase	Mus musculus	0-3
19589965-3	2009	TDH-mediated catabolism of threonine takes place in mitochondria to generate glycine and acetyl-coenzyme A (CoA), with glycine facilitating one-carbon metabolism via the glycine cleavage system and acetyl-CoA feeding the tricarboxylic acid cycle.	Glycine	119-126	L-threonine dehydrogenase	Mus musculus	0-3
19408015-5	2009	FGFR1 is found in ganglion cells and Muller cells, whereas FGFR2 is primarily located in ganglion cells, the nuclei of Muller cells, and glycine-containing amacrine cells.	Glycine	137-144	fibroblast growth factor receptor 2	Mus musculus	59-64
19195858-3	2009	The N-terminal amino acid sequence of its identical 15-kDa subunits was similar to lectins from other Musa species except for the deletion of the N-terminal glycine residue in Del Monte banana lectin.	Glycine	157-164	lectin	Musa acuminata	83-89
15353372-2	2004	This approach has been applied to the ras-p21 protein that becomes oncogenic when single amino acid substitutions occur at critical positions in its polypeptide chain, such as at Gly 12 and Gln 61.	Glycine	179-182	cyclin-dependent kinase inhibitor 1A L homeolog	Xenopus laevis	42-45
19003984-8	2009	As to GSK3beta, the affected positions distribute over activation loop, alpha-helix, and glycine-rich loop.	Glycine	89-96	glycogen synthase kinase 3 beta	Homo sapiens	6-14
15352244-5	2004	Two proteins from the glycine cleavage complex were also identified as putative TRX targets, and a new role can be postulated in leaves for TRX in defense against herbivores and/or pathogens.	Glycine	22-29	thioredoxin H-type 1	Arabidopsis thaliana	80-83
15352244-5	2004	Two proteins from the glycine cleavage complex were also identified as putative TRX targets, and a new role can be postulated in leaves for TRX in defense against herbivores and/or pathogens.	Glycine	22-29	thioredoxin H-type 1	Arabidopsis thaliana	140-143
19272411-0	2009	Mobility of the conserved glycine 155 is required for formation of the active plasmodial Pdx1 dodecamer.	Glycine	26-33	pancreatic and duodenal homeobox 1	Homo sapiens	89-93
19290545-8	2009	Glycine also suppresses the phosphorylation of p42/p44MAPK.	Glycine	0-7	cyclin-dependent kinase 20	Mus musculus	47-50
15262068-3	2004	NR2B antagonists were added after stimulation of NMDA receptors with 10 microM glutamate and 10 microM glycine.	Glycine	103-110	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	0-4
19290545-8	2009	Glycine also suppresses the phosphorylation of p42/p44MAPK.	Glycine	0-7	mitogen-activated protein kinase 3	Mus musculus	51-58
19254951-3	2009	Human and mouse SRAG are 248/249-amino acid arginine- and glycine-rich proteins that are widely expressed in tissues and cell lines.	Glycine	58-65	chromatin target of PRMT1	Mus musculus	16-20
15090552-2	2004	A patient with inherited deficiency of the coagulation serine protease factor XI (FXI) was reported to be homozygous for a Gly(555) --&gt; Glu substitution.	Glycine	123-126	coagulation factor XI	Homo sapiens	82-85
15090552-3	2004	Gly(555) in FXI corresponds to Gly(193) in chymotrypsin, which is the numbering system used subsequently.	Glycine	0-3	coagulation factor XI	Homo sapiens	12-15
15090552-3	2004	Gly(555) in FXI corresponds to Gly(193) in chymotrypsin, which is the numbering system used subsequently.	Glycine	31-34	coagulation factor XI	Homo sapiens	12-15
15004000-7	2004	treating cells cultured on fibronectin with soluble Arg-Gly-Asp-Ser (RGDS) peptide to specifically block integrin-fibronectin interactions.	Glycine	56-59	ral guanine nucleotide dissociation stimulator	Homo sapiens	69-73
19374733-10	2009	Intriguingly, a crucial loop from A4 DBL 3X which provides the important Gly and Lys residues that chelate the bound sulphate is missing or significantly altered in all other DBL domains that interact with CSA.	Glycine	73-76	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	206-209
15171717-5	2004	Bound (125)I-hIGFBP-2 was reversibly displaced by IGFBP-2, IGFBP-1 and RGD-(Gly-Arg-Asp)-containing peptides, but not by IGFBP-3, -4, -5, -6 and RGE-(Gly-Arg-Glu)-containing peptides.	Glycine	76-79	insulin like growth factor binding protein 2	Homo sapiens	13-21
15171717-5	2004	Bound (125)I-hIGFBP-2 was reversibly displaced by IGFBP-2, IGFBP-1 and RGD-(Gly-Arg-Asp)-containing peptides, but not by IGFBP-3, -4, -5, -6 and RGE-(Gly-Arg-Glu)-containing peptides.	Glycine	76-79	insulin like growth factor binding protein 2	Homo sapiens	14-21
19348678-6	2009	We provide evidence that functional excitatory glycine receptors formed regardless of the NR1 isoform, and their pharmacological profile matched the one reported for NR1-1a/NR3: glycine alone fully activated the receptors, which were insensitive to glutamate and block by Mg2+.	Glycine	47-54	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	173-176
15171717-5	2004	Bound (125)I-hIGFBP-2 was reversibly displaced by IGFBP-2, IGFBP-1 and RGD-(Gly-Arg-Asp)-containing peptides, but not by IGFBP-3, -4, -5, -6 and RGE-(Gly-Arg-Glu)-containing peptides.	Glycine	150-153	insulin like growth factor binding protein 2	Homo sapiens	13-21
15171717-5	2004	Bound (125)I-hIGFBP-2 was reversibly displaced by IGFBP-2, IGFBP-1 and RGD-(Gly-Arg-Asp)-containing peptides, but not by IGFBP-3, -4, -5, -6 and RGE-(Gly-Arg-Glu)-containing peptides.	Glycine	150-153	insulin like growth factor binding protein 2	Homo sapiens	14-21
19101823-7	2009	Based on the Ufc1 and Ufm1 NMR structures, a model could be derived for the Ufc1-Ufm1 complex in which the C-terminal Gly(83) of Ufm1 may well form the expected thio-ester with Cys(116), suggesting that Ufm1-Ufc1 functions as described for other E1-E2-E3 machineries.	Glycine	118-121	ubiquitin-fold modifier conjugating enzyme 1	Homo sapiens	13-17
14715656-8	2004	Both ADAMTS-4 and ADAMTS-5 cleaved alpha(2)M at Met(690)/Gly(691), representing a novel proteinase cleavage site within alpha(2)M and a novel site of cleavage for ADAMTS-4 and ADAMTS-5.	Glycine	57-60	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	5-13
19101823-7	2009	Based on the Ufc1 and Ufm1 NMR structures, a model could be derived for the Ufc1-Ufm1 complex in which the C-terminal Gly(83) of Ufm1 may well form the expected thio-ester with Cys(116), suggesting that Ufm1-Ufc1 functions as described for other E1-E2-E3 machineries.	Glycine	118-121	ubiquitin-fold modifier conjugating enzyme 1	Homo sapiens	76-80
19101823-7	2009	Based on the Ufc1 and Ufm1 NMR structures, a model could be derived for the Ufc1-Ufm1 complex in which the C-terminal Gly(83) of Ufm1 may well form the expected thio-ester with Cys(116), suggesting that Ufm1-Ufc1 functions as described for other E1-E2-E3 machineries.	Glycine	118-121	ubiquitin-fold modifier conjugating enzyme 1	Homo sapiens	76-80
19106102-6	2009	In contrast, substitution of distal Glu and Asp residues with Gly or their deletion resulted in pro-Crp4-(20-92) variants with bactericidal and membrane-disruptive activities equal to or greater than that of fully mature Crp4.	Glycine	62-65	defensin, alpha, 4	Mus musculus	100-104
14724269-6	2004	The two most common naturally occurring mutations in MBP result in substitution of acidic amino acids for glycine residues in Gly-X-Y triplets on the N-terminal side of the hinge.	Glycine	106-113	myelin basic protein	Homo sapiens	53-56
14724269-6	2004	The two most common naturally occurring mutations in MBP result in substitution of acidic amino acids for glycine residues in Gly-X-Y triplets on the N-terminal side of the hinge.	Glycine	126-129	myelin basic protein	Homo sapiens	53-56
19120039-5	2009	However, in the African Americans, a non-synonymous single nucleotide polymorphism (i.e. an aspartic acid/glycine coding variant, rs2856966) within exon 2 of PACAP was significantly associated with SIDS (p = 0.004), as were haplotypes containing this polymorphism (p &lt; 0.0001).	Glycine	106-113	adenylate cyclase activating polypeptide 1	Homo sapiens	158-163
15228154-8	2004	MDMA metabolism is rather complex and includes 2 main metabolic pathways: (1) O-demethylenation followed by catechol-O-methyltransferase (COMT)-catalyzed methylation and/or glucuronide/sulfate conjugation; and (2) N-dealkylation, deamination, and oxidation to the corresponding benzoic acid derivatives conjugated with glycine.	Glycine	319-326	catechol-O-methyltransferase	Homo sapiens	138-142
14988435-2	2004	The synthesis of GSH from glutamate, cysteine, and glycine is catalyzed sequentially by two cytosolic enzymes, gamma-glutamylcysteine synthetase and GSH synthetase.	Glycine	51-58	glutamate-cysteine ligase catalytic subunit	Homo sapiens	111-144
19210292-5	2009	GnRH-I is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15), which cleaves the hormone at the covalent bond between the fifth and sixth residue of the decapeptide (Tyr(5)-Gly(6)) to form GnRH-(1-5).	Glycine	185-188	gonadotropin releasing hormone 1	Homo sapiens	0-4
19210292-5	2009	GnRH-I is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15), which cleaves the hormone at the covalent bond between the fifth and sixth residue of the decapeptide (Tyr(5)-Gly(6)) to form GnRH-(1-5).	Glycine	185-188	gonadotropin releasing hormone 1	Homo sapiens	201-205
19118469-5	2009	The glycine molecules interact directly with the FAp (100) surface, where one of their carboxylate groups coordinates with the surface Ca2+ cations.	Glycine	4-11	fibroblast activation protein alpha	Homo sapiens	49-52
14960371-5	2004	NR1 prefers smaller ligands (glycine, serine, and alanine) in comparison with GluRB and GluR0 that bind l-glutamate: the bulky side chain of W731 in NR1 dramatically reduces the size of the ligand-binding site, functioning to selectively restrict recognition to glycine and the d-isomers of serine and alanine.	Glycine	262-269	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	0-3
14960371-5	2004	NR1 prefers smaller ligands (glycine, serine, and alanine) in comparison with GluRB and GluR0 that bind l-glutamate: the bulky side chain of W731 in NR1 dramatically reduces the size of the ligand-binding site, functioning to selectively restrict recognition to glycine and the d-isomers of serine and alanine.	Glycine	262-269	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	149-152
18927217-3	2009	We found that its amino acid sequence (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH(2)) was identical to that of mammalian GnRH.	Glycine	60-63	gonadotropin releasing hormone 1	Homo sapiens	122-126
14966266-4	2004	We show that translation of Sip1 initiates at the second ATG of the open reading frame, yielding a potential site for N myristoylation, and that mutation of the critical glycine abolishes relocalization.	Glycine	170-177	Sip1p	Saccharomyces cerevisiae S288C	28-32
19036632-5	2009	As results of this research we have obtained and characterized a novel complex, glycinate-guanidoacetate nickel (II), [Ni(Gly)(Gaa)], and we deduced the most probable structure using the experimental data of the infrared spectrum in conjunction with the theoretical DFT procedures.	Glycine	122-125	alpha glucosidase	Homo sapiens	127-130
15069780-1	2004	It has been suggested that the Arg 16/Gly 16 allele at codon 16 of beta 2-adrenoceptor polymorphism plays a role in down-regulating the stimulus of bronchodilatation caused by beta 2-agonists.	Glycine	38-41	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	67-73
15069780-2	2004	This study was designed to evaluate the difference of bronchodilator responsiveness to beta 2-agonist (procaterol) and anti-cholinergic drug (oxitropium) between those who have Arg 16/Gly 16 allele (hetero type) and those who have Gly 16/Gly 16 allele (variant type) at codon 16 of in healthy women.	Glycine	184-187	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	87-93
18977415-12	2009	In conclusion, pharmacological inactivation of the glycine-binding site of NMDA receptors may control cannabinoid-induced relapse-like drinking, which is associated with altered expression of CNR1 and NR1 gene expression as observed after WIN treatment.	Glycine	51-58	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	193-196
14662146-0	2004	Effect of folic acid plus glycine supplement on uterine prostaglandin and endometrial granulocyte-macrophage colony-stimulating factor expression during early pregnancy in pigs.	Glycine	26-33	colony stimulating factor 2	Sus scrofa	86-134
18701883-6	2009	Conserved glycine/proline residues are central to the "beta-trefoil fold" characteristic of the secondary structure of FGF family proteins and substitution of these residues is likely to disrupt structure and consequently function.	Glycine	10-17	fibroblast growth factor 3	Homo sapiens	119-122
14713921-2	2004	Recently, Gly m 4 (starvation-associated message 22), a Bet v 1-related pathogenesis-related protein 10 from soy, was suggested to be an allergen in patients with allergic reactions to a dietary product containing a soy protein isolate.	Glycine	10-13	delta/notch like EGF repeat containing	Homo sapiens	56-59
17182766-1	2006	Classical NMDA receptors (NMDARs), activated by glycine and glutamate, are heteromultimers comprised of NR1 and NR2 subunits.	Glycine	48-55	nodal homolog 2 L homeolog	Xenopus laevis	112-115
19365107-10	2009	Upon tumor necrosis factor-alpha stimulation, IL-6 and IL-8 mRNA and protein levels in A549-PLA2G2D-Ser cells were elevated compared with those of A549-PLA2G2D-Gly cells.	Glycine	160-163	phospholipase A2 group IID	Homo sapiens	152-159
14713921-13	2004	Seventy-one percent (67/94) of highly Bet v 1-sensitized patients with birch pollen allergy were sensitized to Gly m 4, and 9 (9.6%) of those patients reported soy allergy.	Glycine	111-114	delta/notch like EGF repeat containing	Homo sapiens	38-41
19365107-11	2009	Upon hydrogen peroxide stimulation, IL-8 mRNA and protein levels in A549-PLA2G2D-Ser cells were higher than those of A549-PLA2G2D-Gly cells.	Glycine	130-133	phospholipase A2 group IID	Homo sapiens	122-129
16980404-1	2006	Serine hydroxymethyl transferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	163-170	pyridoxal phosphatase	Homo sapiens	66-69
19365107-12	2009	CONCLUSIONS: PLA2G2D-Ser enhances the expression of IL-6 and IL-8 compared with PLA2G2D-Gly.	Glycine	88-91	phospholipase A2 group IID	Homo sapiens	80-87
18771702-0	2008	Glycine-extended gastrin stimulates proliferation via JAK2- and Akt-dependent NF-kappaB activation in Barrett"s oesophageal adenocarcinoma cells.	Glycine	0-7	Janus kinase 2	Homo sapiens	54-58
15015733-3	2003	A point mutation of YPD1 that led to a substitution of the 74th glycine (Gly74) to cysteine (Cys) was identified in a mutant strain NH1.	Glycine	64-71	Ypd1p	Saccharomyces cerevisiae S288C	20-24
18852262-5	2008	We have deleted residue Gly-810 from the FMN binding loop in neuronal NOS (nNOS) to give Delta G810 so that the shorter binding loop mimics that in cytochrome P450BM3.	Glycine	24-27	nitric oxide synthase 1	Homo sapiens	61-73
15015733-6	2003	In the reverse turn, glycine (relative position +10 to the active-site histidine) is highly conserved in Ypd1 and other histidine-containing phosphotransfer proteins.	Glycine	21-28	Ypd1p	Saccharomyces cerevisiae S288C	105-109
17210244-9	2006	The first three arginine residues (aa 4-6) of CENP-A appear essential for antibody recognition, as replacing these arginines with glycine residues reduced antibody binding to the expressed CENP-A protein by an average of 93.2% (range 80-100%).	Glycine	130-137	centromere protein A	Homo sapiens	46-52
17210244-9	2006	The first three arginine residues (aa 4-6) of CENP-A appear essential for antibody recognition, as replacing these arginines with glycine residues reduced antibody binding to the expressed CENP-A protein by an average of 93.2% (range 80-100%).	Glycine	130-137	centromere protein A	Homo sapiens	189-195
12951368-4	2003	Similar to hBAT, expressed rBAT was capable of forming both taurine and glycine conjugates with cholyl-CoA.	Glycine	72-79	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	11-15
18852262-5	2008	We have deleted residue Gly-810 from the FMN binding loop in neuronal NOS (nNOS) to give Delta G810 so that the shorter binding loop mimics that in cytochrome P450BM3.	Glycine	24-27	nitric oxide synthase 1	Homo sapiens	75-79
17120122-4	2006	The earliest amino acids, alanine and glycine, have been encoded by GCC and GGC codons, as today.	Glycine	38-45	guanylate cyclase 2C	Homo sapiens	68-71
18930730-6	2008	To determine the role of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in the modulation of this inflammatory response evoked by glycine, we examined its expression levels in fat tissue.	Glycine	145-152	peroxisome proliferator activated receptor gamma	Mus musculus	25-73
18930730-6	2008	To determine the role of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in the modulation of this inflammatory response evoked by glycine, we examined its expression levels in fat tissue.	Glycine	145-152	peroxisome proliferator activated receptor gamma	Mus musculus	75-85
18930730-7	2008	Glycine clearly increased PPAR-gamma expression in lean mice but not in MSG/Ob mice.	Glycine	0-7	peroxisome proliferator activated receptor gamma	Mus musculus	26-36
18930730-10	2008	In conclusion, our findings suggest that glycine suppresses the pro-inflammatory cytokines production and increases adiponectin secretion in vivo through the activation of PPAR-gamma.	Glycine	41-48	peroxisome proliferator activated receptor gamma	Mus musculus	172-182
16973698-8	2006	For 2 ms depolarizations evoking maximal responses, the EAAT5-mediated current carried between 2 and 8 times more charge as an average inhibitory GABA or glycine postsynaptic current received spontaneously from amacrine cells, with 10 mm or 0.5 mm intracellular EGTA, respectively.	Glycine	154-161	solute carrier family 1 (glutamate transporter), member 7	Mus musculus	56-61
18756523-2	2008	The Glycine (Gly) to Arginine (Arg) polymorphism at codon 388 (Gly388Arg), which encodes an amino acid in the transmembrane part of the FGFR4 gene, was reported to be associated with an increased risk in some carcinomas.	Glycine	4-11	fibroblast growth factor receptor 4	Homo sapiens	136-141
16940054-3	2006	Treatment with recombinant neprilysin, but not enzymatically inactive neprilysin, resulted in a slight increase in basic fibroblast growth factor electrophoretic mobility from proteolytic cleavage between amino acids Leu-135 and Gly-136, which was inhibited by the neutral endopeptidase inhibitor CGS24592 and heparin.	Glycine	229-232	membrane metallo endopeptidase	Mus musculus	27-37
14504280-5	2003	The structure of the Mtr2-Mex67 NTF2-like domain complex, which overall is similar to those of the human and Saccharomyces cerevisiae homologs, unveils three putative Phe-Gly repeat binding sites, of which one contributes to the heterodimer interface.	Glycine	171-174	nuclear transport factor 2 like export factor 1	Homo sapiens	21-25
14629468-3	2003	Results of these studies indicate that in the presence of FX (1.5 micro m), the enzyme (active-site-inhibited Glu-Gly-Arg-FIXa, EGR-FIXa) and procofactor (FVIII) bind to an equal number (approximately 700 sites/platelet) of receptors whereas the active cofactor (FVIIIa) binds an additional approximately 500 high-affinity FVIIIa binding sites per platelet (Kd approximately 0.8 nm).	Glycine	114-117	coagulation factor VIII	Homo sapiens	155-160
18756523-2	2008	The Glycine (Gly) to Arginine (Arg) polymorphism at codon 388 (Gly388Arg), which encodes an amino acid in the transmembrane part of the FGFR4 gene, was reported to be associated with an increased risk in some carcinomas.	Glycine	4-7	fibroblast growth factor receptor 4	Homo sapiens	136-141
17074833-6	2006	Biochemical and mutational analysis revealed that the DAB2 cell-adhesion Arg-Gly-Asp (RGD) motif (amino acid residues 64-66) and the alphaIIb-integrin-fibrinogen-binding region (amino acid residues 171-464) are important for the DAB2-platelet interactions.	Glycine	77-80	DAB adaptor protein 2	Homo sapiens	54-58
19033659-6	2008	Additional mutations were identified in the genes encoding the putative glycine transporter SLC6A18 (XT2) and the neutral amino acid transporter SLC6A19 (B0AT1) in families with either IG or HG, suggesting that mutations in the genes encoding these transporters may also contribute to these phenotypes.	Glycine	72-79	solute carrier family 6 member 18	Homo sapiens	92-99
12810727-0	2003	The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine.	Glycine	100-107	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	10-52
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	solute carrier family 7 member 10	Homo sapiens	118-123
12810727-1	2003	Bile acid-CoA:amino acid N-acyltransferase (BACAT) catalyzes the conjugation of bile acids to glycine and taurine for excretion into bile.	Glycine	94-101	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	0-42
12810727-1	2003	Bile acid-CoA:amino acid N-acyltransferase (BACAT) catalyzes the conjugation of bile acids to glycine and taurine for excretion into bile.	Glycine	94-101	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	44-49
16941565-3	2006	CD2BP2 contains a GYF (glycine-tyrosine-phenylalanine) domain that confers binding to these proline-rich sequences.	Glycine	23-30	CD2 cytoplasmic tail binding protein 2	Homo sapiens	0-6
12810727-3	2003	We therefore hypothesized that hBACAT may also hydrolyze fatty acyl-CoAs and/or conjugate fatty acids to glycine.	Glycine	105-112	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	31-37
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	Glycine auxotroph B, complementation of hamster	Homo sapiens	270-274
18981164-0	2008	Multiple glycines in TCR alpha-chains determine clonally diverse nature of human T cell memory to influenza A virus.	Glycine	9-17	T cell receptor alpha constant	Homo sapiens	21-30
12949723-8	2003	Further, dietary glycine largely prevented increases in IL-1beta and TNF-alpha in the colon 2 days after TNBS, and TNBS induction of CINC and MIP-2 in the colonic tissue also was abrogated by glycine.	Glycine	192-199	C-X-C motif chemokine ligand 2	Rattus norvegicus	142-147
12893286-0	2003	Mutagenesis of a Gly-Ser cleavage site in MUC1 inhibits ectodomain shedding.	Glycine	17-20	mucin 1, cell surface associated	Homo sapiens	42-46
17052611-4	2006	In vitro enzyme assays indicated that cauxin hydrolyzed the felinine precursor 3-methylbutanol-cysteinylglycine to felinine and glycine.	Glycine	104-111	carboxylesterase 5A	Felis catus	38-44
19301767-6	2008	Interactions that increased the risk for HF were found in patients carrying at least one of the beta2-AR Glu and beta2-AR Gly allele (OR = 3.81; 95% CI = 1.50-0.70) and beta2-AR Glu and beta1-AR Gly allele combination (OR = 5.51; 95% CI = 2.19-13.86).	Glycine	122-125	adrenoceptor beta 1	Homo sapiens	186-194
16814543-2	2006	Chimera peptides with long spacers (a Lys and five or eight Gly residues) showed synergistically improved affinity for both the mu-opioid receptor and ORL1 receptor, while the chimera peptides with short spacers (Lys residue only) showed decreased or similar affinity compared to the monomeric receptor ligands.	Glycine	60-63	opioid related nociceptin receptor 1	Homo sapiens	151-155
16198476-1	2006	The FGFR4 codon 388 polymorphism (Arg(388), Arg/Gly(388) or Gly(388)) was determined in glioblastoma multiforme (GBM), anaplastic astrocytomas (AA), diffuse astrocytomas (DA), and control muscles.	Glycine	48-51	fibroblast growth factor receptor 4	Homo sapiens	4-9
12893286-8	2003	We conclude that the Gly-Ser peptide bond is required for MUC1 shedding.	Glycine	21-24	mucin 1, cell surface associated	Homo sapiens	58-62
12840230-10	2003	The DING protein (N-terminal amino acid sequence Asp-Ile-Asn-Gly) that binds to genistein with high affinity is one of these.	Glycine	61-64	ring finger protein 2	Homo sapiens	4-8
18662907-4	2008	The glycine-rich loop in AurA adopts a unique bent conformation, forming a pi-pi interaction with the phenyl group of VX-680.	Glycine	4-11	aurora kinase A	Homo sapiens	25-29
16728452-2	2006	Subjects homozygous for glycine at amino acid 16 (Gly16) of the beta2AR have been shown to have enhanced beta2-mediated vascular relaxation when compared to subjects homozygous for arginine (Arg16).	Glycine	24-31	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	64-69
18635641-4	2008	NR1/NR2C receptors activated by a maximally effective concentration of glutamate and glycine had two main conductance levels of 45 pS and 28 pS when the extracellular Ca(2+) concentration was 0.5 mm and the holding potential was -80 mV.	Glycine	85-92	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	4-8
18621031-5	2008	In the presence of alanine, glycine uptake was completely blocked by the GlyT1 inhibitors ALX 5407 and sarcosine, suggesting that the high-affinity glycine uptake occurs predominantly via GlyT1.	Glycine	28-35	hematopoietic SH2 domain containing	Homo sapiens	90-93
16720571-5	2006	The results of this study indicate that (i) the effect of hNPS is mimicked by the fragment hNPS-(1-10); (ii) Phe(2), Arg(3), and Asn(4) are crucial for biological activity; (iii) the sequence Thr(8)-Gly(9)-Met(10) is important for receptor activation, although with non-stringent chemical requirements; and (iv) the sequence Val(6)-Gly(7) acts as a hinge region between the two above-mentioned domains.	Glycine	199-202	neuropeptide S	Homo sapiens	58-62
16720571-5	2006	The results of this study indicate that (i) the effect of hNPS is mimicked by the fragment hNPS-(1-10); (ii) Phe(2), Arg(3), and Asn(4) are crucial for biological activity; (iii) the sequence Thr(8)-Gly(9)-Met(10) is important for receptor activation, although with non-stringent chemical requirements; and (iv) the sequence Val(6)-Gly(7) acts as a hinge region between the two above-mentioned domains.	Glycine	332-335	neuropeptide S	Homo sapiens	58-62
12617724-8	2003	Gly(81), located in subsite -1 of hevamine, where the reaction intermediate is formed, is replaced by Tyr(80) in XIP-I.	Glycine	0-3	xylanase inhibitor protein 1	Triticum aestivum	113-118
18621031-5	2008	In the presence of alanine, glycine uptake was completely blocked by the GlyT1 inhibitors ALX 5407 and sarcosine, suggesting that the high-affinity glycine uptake occurs predominantly via GlyT1.	Glycine	148-155	hematopoietic SH2 domain containing	Homo sapiens	90-93
18572269-7	2008	The rat mast cell line RBL-2H3 were most efficiently transduced with a fiber-mutant Ad5 vector containing the Arg-Gly-Asp (RGD) peptide in the HI loop (Ad-RGD) of the fiber knob.	Glycine	114-117	Alzheimer disease, familial, type 5	Homo sapiens	84-87
12411439-3	2003	The alleles differ at only one amino acid position, where an arginine at position 107 in HLA-E*0101 (E(R)) is replaced by a glycine in HLA-E*0103 (E(G)).	Glycine	124-131	major histocompatibility complex, class I, E	Homo sapiens	89-94
12411439-3	2003	The alleles differ at only one amino acid position, where an arginine at position 107 in HLA-E*0101 (E(R)) is replaced by a glycine in HLA-E*0103 (E(G)).	Glycine	124-131	major histocompatibility complex, class I, E	Homo sapiens	135-140
16820867-6	2006	When 16 a.a. of the FibH SP were used, the secretion of fusion protein was normal and the cleavage site was between the Gly-Ser linker and Met, the starting amino acid of EGFP.	Glycine	120-123	fibroin heavy chain	Bombyx mori	20-24
18637987-6	2008	Two analogs of peptide 2 (Gly-Thr-c[Cys-Phe-Gly-Thr-Cys]-Trp-NH(2), S-S with a free or acetylated N-terminus) inhibited RGS4-stimulated G alpha(o) GTPase activity at 25-50 microM.	Glycine	26-29	regulator of G protein signaling 4	Homo sapiens	120-124
16909847-0	2006	[Molecular dynamics modeling of the substitution of serine for the conservative glycine in the G loop in the yeast cdc28-srm mutant using the crystalline lattice of human kinase CDK2].	Glycine	80-87	cyclin dependent kinase 2	Homo sapiens	178-182
12464396-0	2003	Modulation of cyclooxygenase-2 on glycine- and glutamate-induced ion currents in rat periaqueductal gray neurons.	Glycine	34-41	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	14-30
12464396-3	2003	In the present study, the modulatory effect of COX-2 on glycine- and glutamate-induced ion currents in periaqueductal gray (PAG) neurons was investigated using the nystatin-perforated patch clamp method.	Glycine	56-63	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	47-52
12464396-5	2003	In contrast, continuous application of celecoxib, selective COX-2 inhibitor, resulted in decreased glycine-induced ion current and increased glutamate-induced ion current.	Glycine	99-106	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	60-65
18570467-7	2008	However, the rupture of the Gly( P 1) approximately Ile( P 1") amide bond is destabilized in the static QM/MM calculations, owing to the positioning of the Ile( P 1") side chain inside the MMP-2 S 1" pocket and to the inability of simple energy miminization methodologies to properly relax complex systems.	Glycine	28-31	matrix metallopeptidase 2	Homo sapiens	189-194
12568929-6	2003	We also determined the recognition structure of EDA(+)FN for Hep by an inhibition experiment on the heparin binding domain II (HepII) in EDA(+)FN with the synthetic peptides, Arg-Arg-Ala-Arg (RRAR), Asp-Gln-Ala-Arg (DNAR), Ile-Lys-Tyr-Glu-Lys (IKYEK), and Gly-Arg-Lys-Lys-Try (GRKKT).	Glycine	256-259	ectodysplasin A	Homo sapiens	48-51
16751771-7	2006	SLC6A5 mutations result in defective subcellular GlyT2 localization, decreased glycine uptake or both, with selected mutations affecting predicted glycine and Na+ binding sites.	Glycine	79-86	solute carrier family 6 member 5	Homo sapiens	0-6
16751771-7	2006	SLC6A5 mutations result in defective subcellular GlyT2 localization, decreased glycine uptake or both, with selected mutations affecting predicted glycine and Na+ binding sites.	Glycine	147-154	solute carrier family 6 member 5	Homo sapiens	0-6
18427837-4	2008	Exposure to Gly drastically increased mRNA expression of the calcified chondrocyte marker osteopontin, without markedly affecting that of a proliferating chondrocyte marker or a hypertrophic chondrocyte marker, as shown in organotypic cultures by in situ hybridization analysis.	Glycine	12-15	secreted phosphoprotein 1	Rattus norvegicus	90-101
16794345-1	2006	Recently we showed that the glycine-rich loop in the N-terminal portion of protein kinases and the client-binding site of Cdc37 are both necessary for interaction between Cdc37 and protein kinases.	Glycine	28-35	cell division cycle 37, HSP90 cochaperone	Homo sapiens	122-127
16794345-1	2006	Recently we showed that the glycine-rich loop in the N-terminal portion of protein kinases and the client-binding site of Cdc37 are both necessary for interaction between Cdc37 and protein kinases.	Glycine	28-35	cell division cycle 37, HSP90 cochaperone	Homo sapiens	171-176
12467574-1	2002	Glutathione synthase catalyzes the final ATP-dependent step in glutathione biosynthesis, the formation of glutathione from gamma-glutamylcysteine and glycine.	Glycine	150-157	glutathione synthase	Saccharomyces cerevisiae S288C	0-20
12609057-5	2002	DNA sequencing revealed a missense mutation of GCT to GGT in code 136 of PS-1 exon 5, leading to the substitution of Ala with Gly (Ala136Gly), in these 9 persons.	Glycine	126-129	presenilin 1	Homo sapiens	73-77
16720724-2	2006	FKBP12 binds to the glycine- and serine-rich motif (GS motif) of the TGF-beta type I receptor, and functions as a secure switch to prevent the leaky signal.	Glycine	20-27	FKBP prolyl isomerase 1A	Homo sapiens	0-6
18427837-5	2008	Gly significantly increased Ca2+ accumulation, osteopontin mRNA expression, and alkaline phosphatase activity in cultured rat costal chondrocytes, without significantly affecting those in cultured rat calvarial osteoblasts.	Glycine	0-3	secreted phosphoprotein 1	Rattus norvegicus	47-58
18564178-1	2008	It has been recently established that in various brain regions D-serine, the product of serine racemase, occupies the so-called "glycine site" within N-methyl D-aspartate receptors.	Glycine	129-136	serine racemase	Homo sapiens	88-103
16569642-3	2006	In addition, IGFBP2 has an Arg-Gly-Asp (RGD) domain, which is a known integrin binding motif.	Glycine	31-34	insulin like growth factor binding protein 2	Homo sapiens	13-19
18491921-7	2008	After adenylation, persulfurated Uba4 was able to form a thiocarboxylate group at the C-terminal glycine of either Urm1 or MOCS2A.	Glycine	97-104	ubiquitin related modifier 1	Homo sapiens	115-119
16450403-2	2006	NKH is caused by deficiency of the glycine cleavage multi-enzyme system with three specific components encoded by GLDC, AMT, and GCSH.	Glycine	35-42	glycine decarboxylase	Homo sapiens	114-118
16450403-2	2006	NKH is caused by deficiency of the glycine cleavage multi-enzyme system with three specific components encoded by GLDC, AMT, and GCSH.	Glycine	35-42	glycine cleavage system protein H	Homo sapiens	129-133
12382291-5	2002	Two hypotheses have been proposed to explain the catalytic inefficiency of MIF: the lower basicity of primary amines with regard to secondary ones and the increased flexibility resulting from the replacement of a proline by residues like glycine.	Glycine	238-245	macrophage migration inhibitory factor	Homo sapiens	75-78
12417259-5	2002	When a MARCKS (myristoylated alanine-rich C-kinase substrate)-derived peptide substrate (Gly-Ala-Gln-Phe-Ser-Lys-Thr-Ala-Arg-Arg) and the M2 gene segment of the reovirus type 3 peptide substrate (Gly-Asn-Ala-Ser-Ser-Ile-Lys-Lys-Lys) were used, hNMT activity was increased by approximately 8.5- and 7-fold, respectively.	Glycine	89-92	myristoylated alanine rich protein kinase C substrate	Homo sapiens	7-13
12383475-2	2002	After rat liver homogenate was incubated in the presence of substrates and pyridoxal 5"-phosphate, the pyruvate and glycine produced by AGT were measured.	Glycine	116-123	alanine--glyoxylate and serine--pyruvate aminotransferase	Rattus norvegicus	136-139
12383475-3	2002	The AGT activity was 10.02+/-0.31 micro mol pyruvate/h/mg protein and 10.21+/-0.15 micro mol glycine/h/mg protein.	Glycine	93-100	alanine--glyoxylate and serine--pyruvate aminotransferase	Rattus norvegicus	4-7
18490713-8	2008	We delineated two distinct release pathways: the well-known caspase-1 cascade mediating release of processed IL-1beta that was selectively blocked by inhibition of caspase-1 or panx1, and a calcium-independent, caspase-1/panx1-independent release of pro-IL-1beta that was selectively blocked by glycine.	Glycine	295-302	caspase 1	Mus musculus	60-69
12417033-6	2002	Among these putative protein methylacceptors, three are heterogeneous nuclear ribonucleoproteins (hnRNPA2/B1 and hnRNP K) that are reportedly methylated in their arginine- and glycine-rich RGG motifs.	Glycine	176-183	heterogeneous nuclear ribonucleoprotein K	Homo sapiens	113-120
16379012-3	2006	We investigated the effect of an alanine to glycine substitution found in the NEMO polypeptide of an EDA-ID patient.	Glycine	44-51	ectodysplasin A	Homo sapiens	101-104
18436238-8	2008	Rather, we have discovered that the carboxy-terminal glycine-rich region of the NF-kappaB p50 homodimer is involved in mediating high-affinity binding of I kappaB zeta and NF-kappaB p50.	Glycine	53-60	NFKB inhibitor zeta	Homo sapiens	154-167
18412318-6	2008	PEGylated peptides [Gly (8),Aib (22)]GLP-1(7-37)-Cys ((PEG))-Ala-NH2 (23) and c[Glu (22)-Lys (26)][Gly (8)]GLP-1(7-37)-Cys ((PEG))-Ser-Gly-NH2 (24) retained picomolar functional potency and avid receptor binding properties.	Glycine	99-102	glucagon like peptide 1 receptor	Homo sapiens	37-42
18342636-10	2008	The crystal structures and the mutation data suggest that having a glycine at residue 72 of cSDH is the major reason for the reduction of catalytic activity of cSDH.	Glycine	67-74	serine dehydratase like	Homo sapiens	92-96
16505175-8	2006	Furthermore, bisindolylmaleimide I prevented Gly-BSA-stimulated Rac1 translocation, an essential step for NADPH oxidase activation.	Glycine	45-48	Rac family small GTPase 1	Rattus norvegicus	64-68
16303767-6	2006	Each purified mutant Atg8 homolog with an exposed C-terminal Gly formed an E1-substrate intermediate with hAtg7 via a thioester bond in an ATP-dependent manner and formed an E2-substrate intermediate with hAtg3 via a thioester bond dependent on ATP and hAtg7.	Glycine	61-64	autophagy related 7	Homo sapiens	106-111
16303767-6	2006	Each purified mutant Atg8 homolog with an exposed C-terminal Gly formed an E1-substrate intermediate with hAtg7 via a thioester bond in an ATP-dependent manner and formed an E2-substrate intermediate with hAtg3 via a thioester bond dependent on ATP and hAtg7.	Glycine	61-64	autophagy related 7	Homo sapiens	253-258
12513909-7	2002	Three-dimensional models of IL-22 and IL-10 receptor complexes suggest two receptor residues (Gly-44 and Arg-96) are largely responsible for the marked differences in ligand affinity observed for sIL-10R1 and sIL-22R vs. sIL-10R2.	Glycine	94-97	STIL centriolar assembly protein	Homo sapiens	196-199
12513909-7	2002	Three-dimensional models of IL-22 and IL-10 receptor complexes suggest two receptor residues (Gly-44 and Arg-96) are largely responsible for the marked differences in ligand affinity observed for sIL-10R1 and sIL-22R vs. sIL-10R2.	Glycine	94-97	STIL centriolar assembly protein	Homo sapiens	209-212
12513909-7	2002	Three-dimensional models of IL-22 and IL-10 receptor complexes suggest two receptor residues (Gly-44 and Arg-96) are largely responsible for the marked differences in ligand affinity observed for sIL-10R1 and sIL-22R vs. sIL-10R2.	Glycine	94-97	STIL centriolar assembly protein	Homo sapiens	209-212
12271491-8	2002	Double labeling with antisera against AQP1 and gamma-aminobutyric acid or glycine demonstrated that these AQP1-like-immunoreactive amacrine cells were immunoreactive for glycine.	Glycine	74-81	aquaporin 1	Rattus norvegicus	106-110
18342636-10	2008	The crystal structures and the mutation data suggest that having a glycine at residue 72 of cSDH is the major reason for the reduction of catalytic activity of cSDH.	Glycine	67-74	serine dehydratase like	Homo sapiens	160-164
12271491-8	2002	Double labeling with antisera against AQP1 and gamma-aminobutyric acid or glycine demonstrated that these AQP1-like-immunoreactive amacrine cells were immunoreactive for glycine.	Glycine	170-177	aquaporin 1	Rattus norvegicus	38-42
12271491-8	2002	Double labeling with antisera against AQP1 and gamma-aminobutyric acid or glycine demonstrated that these AQP1-like-immunoreactive amacrine cells were immunoreactive for glycine.	Glycine	170-177	aquaporin 1	Rattus norvegicus	106-110
18202139-7	2008	Patch clamp recordings on laminae IV-VI demonstrated that bath-applied ghrelin (100 nm) induced a strong increase of spontaneous gamma-aminobutyric acid/glycine-mediated current frequency (463 +/- 93% of the control) and amplitude (150 +/- 16% of the control) in about 60% of recorded neurons.	Glycine	153-160	ghrelin	Mus musculus	71-78
12238936-2	2002	Among these compounds, the glycine derivative 3a and beta-alanine derivative 3f exhibited the most potent inhibition of squalene synthase prepared from HepG2 cells (IC(50) = 15 nM).	Glycine	27-34	farnesyl-diphosphate farnesyltransferase 1	Homo sapiens	120-137
16014697-10	2006	A serine/glycine substitution in OAS1 exon 3 is more likely a functional variant.	Glycine	9-16	2'-5'-oligoadenylate synthetase 1	Homo sapiens	33-37
16374775-1	2006	In the present work, RGDS (Arg-Gly-Asp-Ser) was immobilized on PLLA scaffolds with plasma treatment.	Glycine	31-34	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	21-25
18341310-1	2008	PBE1PBE/6-311+G(d,p) computations exploring the microsolvation of neutral and zwitterionic glycine are reported.	Glycine	91-98	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	Homo sapiens	0-13
16409473-0	2006	The Ser219--&gt;Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype.	Glycine	16-19	protein C receptor	Homo sapiens	38-68
18268017-4	2008	By generating a series of chimeric and point mutants of p38alpha and p38beta, we found two amino acid residues (Asp(145) and Leu(156) in p38alpha, Gly(145) and Val(156) in p38beta) that determine the distinct subcellular locations of p38alpha-PRAK and p38beta-PRAK.	Glycine	147-150	mitogen-activated protein kinase 14	Mus musculus	56-64
12115475-5	2002	To encourage cell adhesion, PEUUs were surface modified with radio-frequency glow discharge followed by coupling of Arg-Gly-Asp-Ser (RGDS).	Glycine	120-123	ral guanine nucleotide dissociation stimulator	Homo sapiens	133-137
16246290-0	2005	Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker.	Glycine	139-146	myelin basic protein	Homo sapiens	105-125
18426410-2	2008	We showed earlier that activation of PAR-2 with Ser-Leu-Ile-Gly-Arg-Leu-NH(2) (SLIGRL), a known PAR-2 activating peptide, induces keratinocyte phagocytosis and increases skin pigmentation, indicating that PAR-2 regulates pigmentation by controlling phagocytosis of melanosomes.	Glycine	60-63	F2R like trypsin receptor 1	Homo sapiens	37-42
16252083-5	2005	We performed a case-control study to test the association between two polymorphisms in the hMSH2 gene: an A --&gt; G transition at 127 position producing an Asn --&gt; Ser substitution at codon 127 (the Asn127Ser polymorphism) and a G --&gt; A transition at 1032 position resulting in a Gly --&gt; Asp change at codon 322 (the Gly322Asp polymorphism) and breast cancer risk and cancer progression.	Glycine	287-290	mutS homolog 2	Homo sapiens	91-96
12110330-1	2002	In order to improve the immunotherapeutical potential of H-Cys-Leu-Gly-Gly-Leu-Leu-Thr-Met-Val-OH (CLG) peptide, an Epstein-Barr virus (EBV) subdominant epitope derived from the membrane protein LMP2, we have synthesized and tested CLG analogues containing cis- and/or trans-4-aminocyclohexanecarboxylic acid (ACCA) replacing Gly-Gly and/or Thr-Met dipeptide units.	Glycine	67-70	BGRF1-BDRF1 protein	Human gammaherpesvirus 4	195-199
18426410-2	2008	We showed earlier that activation of PAR-2 with Ser-Leu-Ile-Gly-Arg-Leu-NH(2) (SLIGRL), a known PAR-2 activating peptide, induces keratinocyte phagocytosis and increases skin pigmentation, indicating that PAR-2 regulates pigmentation by controlling phagocytosis of melanosomes.	Glycine	60-63	F2R like trypsin receptor 1	Homo sapiens	96-101
18426410-2	2008	We showed earlier that activation of PAR-2 with Ser-Leu-Ile-Gly-Arg-Leu-NH(2) (SLIGRL), a known PAR-2 activating peptide, induces keratinocyte phagocytosis and increases skin pigmentation, indicating that PAR-2 regulates pigmentation by controlling phagocytosis of melanosomes.	Glycine	60-63	F2R like trypsin receptor 1	Homo sapiens	96-101
18067928-2	2008	In the present study, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) in CYP1B1 that cause amino acid changes (Arg-Gly at codon 48, Ala-Ser at codon 119, Leu-Val at codon 432 and Asn-Ser at codon 453) were studied in 150 cases suffering from head and neck squamous cell carcinoma (HNSCC) and in an equal number of controls.	Glycine	149-152	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	107-113
12119357-4	2002	Time-lapse analysis of p150(Glued) revealed targeting to the plus ends of growing microtubules, requiring the NH2-terminal cytoskeleton-associated protein-glycine rich domain, but not EB1 or CLIP-170.	Glycine	155-162	chromatin assembly factor 1 subunit A	Homo sapiens	23-27
16271045-8	2005	We hypothesize that PSD-95 might act as a scaffold for GLYT1 and NMDA receptors, allowing GLYT1 to regulate the concentrations of glycine in the micro-environment of NMDA receptors.	Glycine	130-137	discs large MAGUK scaffold protein 4	Rattus norvegicus	20-26
18301339-2	2008	Single nucleotide polymorphisms of PECAM-1 encoding amino acid substitutions at positions 98 leucine/valine (L/V), 536 serine/asparagine (S/N), and 643 arginine/glycine (R/G) occur in strong genetic linkage resulting in two common haplotypes (LSR and VNG).	Glycine	161-168	platelet and endothelial cell adhesion molecule 1	Homo sapiens	35-42
16272181-1	2005	The novel human differentiating factor peptide fragment HLDF6 (Thr-Gly-Glu-Asn-His-Arg) was synthesized and purified.	Glycine	67-70	ribosomal protein S21	Homo sapiens	56-61
16014632-3	2005	E2 proteins are key enzymes and form a thioester intermediate through their catalytic cysteine with the C-terminal glycine (Gly76) of ubiquitin.	Glycine	115-122	ubiquitin	Saccharomyces cerevisiae S288C	134-143
16077993-2	2005	We found that the SNL glycoprotein consists of carbohydrate (69.74%) and protein content (30.26%), which has &gt;50% hydrophobic amino acids containing glycine and proline.	Glycine	152-159	fascin actin-bundling protein 1	Homo sapiens	18-21
12077323-3	2002	Here, we have generated mouse knock-in (KI) mutants harboring a critical valine-to-glycine substitution in the amino-terminal zinc fingers of GATA-1 and GATA-2 to ablate FOG interaction.	Glycine	83-90	GATA binding protein 1	Mus musculus	142-148
12077323-3	2002	Here, we have generated mouse knock-in (KI) mutants harboring a critical valine-to-glycine substitution in the amino-terminal zinc fingers of GATA-1 and GATA-2 to ablate FOG interaction.	Glycine	83-90	GATA binding protein 2	Mus musculus	153-159
12077323-3	2002	Here, we have generated mouse knock-in (KI) mutants harboring a critical valine-to-glycine substitution in the amino-terminal zinc fingers of GATA-1 and GATA-2 to ablate FOG interaction.	Glycine	83-90	zinc finger protein, multitype 1	Mus musculus	170-173
16075109-1	2005	Multi-stage mass spectrometry (MSn) on [(M + Ag - H)x + Ag]+ precursor ions (where M = an amino acid such as glycine or N,N-dimethylglycine) results in the formation of stable silver (Ag3+, Ag5+ and Ag7+) and silver hydride (Ag2H+, Ag4H+ and Ag6H+) cluster cations in the gas phase.	Glycine	109-116	anterior gradient 3, protein disulphide isomerase family member	Homo sapiens	184-187
17962394-7	2008	A novel missense c.686C&gt;G mutation, which causes the substitution of a conserved arginine at amino acid position 229 by glycine (p.R229G) in exon 8 of the FRMD7 gene, was observed.	Glycine	123-130	FERM domain containing 7	Homo sapiens	158-163
16043459-9	2005	KA, glycine, DA, ACh, GABA, and 5-HT partially blocked Kir through their respective receptors.	Glycine	4-11	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	Homo sapiens	55-58
12031415-4	2002	While showing similarities to the TM regions of other mammalian IGHM chains, the highly conserved Ser residue of the CART motif is substituted with a Gly in the dolphin.	Glycine	150-153	immunoglobulin heavy constant mu	Homo sapiens	64-68
17884945-4	2008	In this study, fasted mice were administered Gly(2)-GLP-2 or LR(3)-IGF-I (positive control) for 0.5-4 h. Nuclear translocation of beta-catenin in non-Paneth crypt cells was assessed by immunohistochemistry and expression of its downstream proliferative markers, c-myc and Sox9, by quantitative RT-PCR.	Glycine	45-48	glucagon-like peptide 2 receptor	Mus musculus	52-57
12126939-0	2002	Novel mutations in the P-protein (glycine decarboxylase) gene in patients with glycine encephalopathy (non-ketotic hyperglycinemia).	Glycine	34-41	OCA2 melanosomal transmembrane protein	Homo sapiens	23-32
12126939-1	2002	Eight novel mutations were found in the P-protein (glycine decarboxylase) gene (GLDC) of the glycine cleavage system (EC 2.1.1.10) by screening five exons of the gene in patients with glycine encephalopathy (NKH).	Glycine	51-58	OCA2 melanosomal transmembrane protein	Homo sapiens	40-49
12126939-1	2002	Eight novel mutations were found in the P-protein (glycine decarboxylase) gene (GLDC) of the glycine cleavage system (EC 2.1.1.10) by screening five exons of the gene in patients with glycine encephalopathy (NKH).	Glycine	51-58	glycine decarboxylase	Homo sapiens	80-84
12126939-1	2002	Eight novel mutations were found in the P-protein (glycine decarboxylase) gene (GLDC) of the glycine cleavage system (EC 2.1.1.10) by screening five exons of the gene in patients with glycine encephalopathy (NKH).	Glycine	51-58	glycine cleavage system protein H	Homo sapiens	208-211
12126939-1	2002	Eight novel mutations were found in the P-protein (glycine decarboxylase) gene (GLDC) of the glycine cleavage system (EC 2.1.1.10) by screening five exons of the gene in patients with glycine encephalopathy (NKH).	Glycine	93-100	OCA2 melanosomal transmembrane protein	Homo sapiens	40-49
12126939-1	2002	Eight novel mutations were found in the P-protein (glycine decarboxylase) gene (GLDC) of the glycine cleavage system (EC 2.1.1.10) by screening five exons of the gene in patients with glycine encephalopathy (NKH).	Glycine	93-100	glycine decarboxylase	Homo sapiens	51-72
12126939-1	2002	Eight novel mutations were found in the P-protein (glycine decarboxylase) gene (GLDC) of the glycine cleavage system (EC 2.1.1.10) by screening five exons of the gene in patients with glycine encephalopathy (NKH).	Glycine	93-100	glycine decarboxylase	Homo sapiens	80-84
15969502-2	2005	The copresence of the two known genetic variants A (Asp(244)) and B (Gly(244)) was ascertained in bovine chymosin.	Glycine	69-72	chymosin	Bos taurus	105-113
19030106-7	2008	The presence of a glycine residue in this position contributes to the specificity of TAE226 and related compounds for FAK.	Glycine	18-25	protein tyrosine kinase 2	Homo sapiens	118-121
15906014-7	2005	A recombinant human cystatin C variant with Gly substitutions for residues Arg8, Leu9, Val10, and Trp106 did not inhibit bone resorption, had 1,000-fold decreased inhibitory effect on cathepsin K activity compared to wildtype cystatin C, but was equipotent with wildtype cystatin C as an inhibitor of osteoclastogenesis.	Glycine	44-47	cystatin C	Homo sapiens	20-30
15716048-6	2005	The inhibition of ODC activity in cells exposed to L-methionine or L-arginine was due to a decreased abundance of ODC protein without change at the mRNA level and each of these amino acids could counteract ODC induction by a glycine supplement.	Glycine	225-232	ornithine decarboxylase 1	Homo sapiens	18-21
12126939-1	2002	Eight novel mutations were found in the P-protein (glycine decarboxylase) gene (GLDC) of the glycine cleavage system (EC 2.1.1.10) by screening five exons of the gene in patients with glycine encephalopathy (NKH).	Glycine	93-100	glycine cleavage system protein H	Homo sapiens	208-211
15716048-6	2005	The inhibition of ODC activity in cells exposed to L-methionine or L-arginine was due to a decreased abundance of ODC protein without change at the mRNA level and each of these amino acids could counteract ODC induction by a glycine supplement.	Glycine	225-232	ornithine decarboxylase 1	Homo sapiens	114-117
18289107-3	2008	Alanine:glyoxylate aminotransferase (AGT) is a peroxisomal pyridoxal 5"-phosphate (PLP) dependent enzyme which catalyzes the transamination of alanine and glyoxylate to pyruvate and glycine.	Glycine	182-189	pyridoxal phosphatase	Homo sapiens	83-86
15716048-6	2005	The inhibition of ODC activity in cells exposed to L-methionine or L-arginine was due to a decreased abundance of ODC protein without change at the mRNA level and each of these amino acids could counteract ODC induction by a glycine supplement.	Glycine	225-232	ornithine decarboxylase 1	Homo sapiens	114-117
15878348-3	2005	Comparison of sequences of the Smu1 gene from wild-type and mutant cells revealed that the mutant phenotype is caused by a G-to-A transition that yields a gly-to-arg substitution at position 489 in hamster Smu1.	Glycine	155-158	SMU1 DNA replication regulator and spliceosomal factor	Homo sapiens	31-35
15878348-4	2005	The substituted glycine is located in the WD-repeat domain of Smu1.	Glycine	16-23	SMU1 DNA replication regulator and spliceosomal factor	Homo sapiens	62-66
11959859-4	2002	Both mPAT1 and mPAT2 induced a pH-dependent electrogenic transport activity for small amino acids (glycine, alanine, and proline) that is altered by membrane potential.	Glycine	99-106	solute carrier family 36 (proton/amino acid symporter), member 2	Mus musculus	15-20
17928413-3	2007	This is a two-step process in which l-arginine:glycine amidinotransferase (AGAT) catalyzes the conversion of glycine and arginine to ornithine and guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT) then catalyzes the S-adenosylmethionine-dependent methylation of GAA to creatine.	Glycine	47-54	glycine amidinotransferase	Rattus norvegicus	75-79
12079500-7	2002	Mutation of the conserved glycine (G147) to alanine eliminated binding of the 5-HT3R antagonist [3H]granisetron.	Glycine	26-33	5-hydroxytryptamine (serotonin) receptor 3A	Mus musculus	78-84
15992355-1	2005	Aminopeptidase N (APN; CD13) is a member of zinc-containing ectoenzymes family involved in the degradation of neutral or basic amino acids (Ala&gt;Phe&gt;Leu&gt;Gly) from N-terminal of bioactive peptides and amide or arylamide derivatives of amino acids.	Glycine	161-164	alanyl aminopeptidase, membrane	Homo sapiens	0-16
15992355-1	2005	Aminopeptidase N (APN; CD13) is a member of zinc-containing ectoenzymes family involved in the degradation of neutral or basic amino acids (Ala&gt;Phe&gt;Leu&gt;Gly) from N-terminal of bioactive peptides and amide or arylamide derivatives of amino acids.	Glycine	161-164	alanyl aminopeptidase, membrane	Homo sapiens	18-21
15992355-1	2005	Aminopeptidase N (APN; CD13) is a member of zinc-containing ectoenzymes family involved in the degradation of neutral or basic amino acids (Ala&gt;Phe&gt;Leu&gt;Gly) from N-terminal of bioactive peptides and amide or arylamide derivatives of amino acids.	Glycine	161-164	alanyl aminopeptidase, membrane	Homo sapiens	23-27
12031963-3	2002	Here, we test the hypothesis that the putative transporter is the vesicular inhibitory amino acid transporter (VIAAT), a neuronal transmembrane transporter of GABA and glycine.	Glycine	168-175	solute carrier family 32 member 1	Rattus norvegicus	111-116
17928413-3	2007	This is a two-step process in which l-arginine:glycine amidinotransferase (AGAT) catalyzes the conversion of glycine and arginine to ornithine and guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT) then catalyzes the S-adenosylmethionine-dependent methylation of GAA to creatine.	Glycine	47-54	guanidinoacetate N-methyltransferase	Rattus norvegicus	171-205
17928413-3	2007	This is a two-step process in which l-arginine:glycine amidinotransferase (AGAT) catalyzes the conversion of glycine and arginine to ornithine and guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT) then catalyzes the S-adenosylmethionine-dependent methylation of GAA to creatine.	Glycine	47-54	guanidinoacetate N-methyltransferase	Rattus norvegicus	207-211
15826505-1	2005	Dihydrolipoamide dehydrogenase (E3) catalyzes the reoxidation of dihydrolipoyl moiety of the acyltransferase components of three alpha-keto acid dehydrogenase complexes and of the hydrogen-carrier protein of the glycine cleavage system.	Glycine	212-219	dihydrolipoamide dehydrogenase	Homo sapiens	0-30
18158646-2	2007	It is formed in a two-step enzymatic process including, first, the formation of gamma-glutamylcysteine from glutamate and cysteine, by the activity of the gamma-glutamylcysteine synthetase; and second, the formation of GSH by the activity of GSH synthetase which uses gamma-glutamylcysteine and glycine as substrates.	Glycine	295-302	glutamate-cysteine ligase catalytic subunit	Homo sapiens	155-188
15743838-3	2005	Complex formation in vitro and in vivo requires a 63-residue glycine-arginine-rich (GAR) domain located at the extreme C terminus of nucleolin, with this domain sufficient to inhibit DNA replication in vitro.	Glycine	61-68	nucleolin	Homo sapiens	133-142
12044560-2	2002	It represents a novel combination of known methods, and is based on the formation of glutathione (GSH) from cysteine, glutamate and glycine in the presence of rat kidney GS for the assay of gamma-GCS, or from gamma-glutamylcysteine and glycine for the assay of GS.	Glycine	132-139	glutamate-cysteine ligase catalytic subunit	Homo sapiens	190-199
17917276-0	2007	The effects of glycine and L-arginine on heat stability of ginsenoside Rb1.	Glycine	15-22	RB transcriptional corepressor 1	Homo sapiens	71-74
15632290-1	2005	Molecular dynamics (MD) simulations were used to explain structural details of cyclin-dependent kinase-2 (CDK2) inhibition by phosphorylation at T14 and/or Y15 located in the glycine-rich loop (G-loop).	Glycine	175-182	cyclin dependent kinase 2	Homo sapiens	79-104
17828277-3	2007	Here we use the complex formed between the CAP-Gly domain of p150(glued) and the C-terminal zinc knuckle of CLIP170 as a model system to explore the structure-function relationship of CAP-Gly-mediated protein interactions.	Glycine	47-50	chromatin assembly factor 1 subunit A	Homo sapiens	61-72
15632290-1	2005	Molecular dynamics (MD) simulations were used to explain structural details of cyclin-dependent kinase-2 (CDK2) inhibition by phosphorylation at T14 and/or Y15 located in the glycine-rich loop (G-loop).	Glycine	175-182	cyclin dependent kinase 2	Homo sapiens	106-110
15864413-0	2005	A single nucleotide substitution that abolishes the initiator methionine codon of the GLDC gene is prevalent among patients with glycine encephalopathy in Jerusalem.	Glycine	129-136	glycine decarboxylase	Homo sapiens	86-90
11930008-2	2002	Osteopontin (OPN) is an extracellular matrix protein containing Arg-Gly-Asp (RGD) sequence, which interacts with alpha(v)beta3 integrins, promotes cell attachment, and cell migration and is expressed in both synovial cells and chondrocytes in rheumatoid arthritis; however, its functional relationship to arthritis has not been known.	Glycine	68-71	secreted phosphoprotein 1	Mus musculus	13-16
11870079-12	2002	Incubation of OPN-coated microbeads with porcine trophectoderm and uterine luminal epithelial cells induced Arg-Gly-Asp (RGD)-dependent integrin activation and transmembrane accumulation of cytoskeletal molecules at the apical cell surface as assessed by immunofluorescence detection of talin or alpha-actinin as markers for focal adhesions.	Glycine	112-115	secreted phosphoprotein 1	Sus scrofa	14-17
15635723-0	2005	Efficient synthesis and comparative studies of the arginine and Nomega,Nomega-dimethylarginine forms of the human nucleolin glycine/arginine rich domain.	Glycine	124-131	nucleolin	Homo sapiens	114-123
17828277-3	2007	Here we use the complex formed between the CAP-Gly domain of p150(glued) and the C-terminal zinc knuckle of CLIP170 as a model system to explore the structure-function relationship of CAP-Gly-mediated protein interactions.	Glycine	188-191	chromatin assembly factor 1 subunit A	Homo sapiens	61-72
15635723-1	2005	The Gly- and Arg-rich C-terminal region of human nucleolin is a 61-residue long domain involved in a number of protein-protein and protein-nucleic acid interactions.	Glycine	4-7	nucleolin	Homo sapiens	49-58
11814344-9	2002	Based on these data, we conclude that when hENT1 is expressed in yeast, glycine 179 is critical not only to the ability of hENT1 to transport uridine but also as a determinant of hENT1 sensitivity to NBMPR.	Glycine	72-79	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	123-128
17521919-0	2007	Involvement of Gly 311 residue on substrate discrimination, pH and temperature dependency of recombinant Staphylococcus xylosus lipase: a study with emulsified substrate.	Glycine	15-18	YSIRK-type signal peptide-containing protein	Staphylococcus xylosus	128-134
11814344-9	2002	Based on these data, we conclude that when hENT1 is expressed in yeast, glycine 179 is critical not only to the ability of hENT1 to transport uridine but also as a determinant of hENT1 sensitivity to NBMPR.	Glycine	72-79	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	123-128
11791000-1	2002	The signaling impact of a human beta1-adrenergic receptor (beta1 AR) polymorphism at residue 49 of the aminoterminus (Ser-to-Gly substitution) was studied by recombinantly expressing each receptor.	Glycine	125-128	adrenoceptor beta 1	Homo sapiens	32-67
11883703-9	2002	These results also support the hypothesis that PC5 in differentiated neuronal cells is capable of processing pro CCK to glycine-extended CCK 8.	Glycine	120-127	proprotein convertase subtilisin/kexin type 5	Homo sapiens	47-50
15518907-6	2004	We conclude that [Arg15,20,21 Leu17]-PACAP-Gly-Lys-Arg-NH2 produces significant concentration-dependent and sustained bronchial smooth muscle relaxation in vitro.	Glycine	43-46	adenylate cyclase activating polypeptide 1	Homo sapiens	37-42
15385554-4	2004	This work characterizes eight recently identified high glycine/tyrosine (HGT)-type KAP genes collectively designated Krtap16-n.	Glycine	55-62	keratin associated protein 31-1	Mus musculus	83-86
17548045-4	2007	The CD23-based substrate, Dabcyl-His-Gly-Asp-Gln-Met-Ala-Gln-Lys-Ser-Lys(Fam)-NH2, is more selective, being hydrolyzed efficiently only by ADAM8 and ADAM10.	Glycine	37-40	Fc epsilon receptor II	Homo sapiens	4-8
15578758-9	2004	This result is in agreement with the previously obtained data from multiple sequence alignment of S. rimosus lipase with different esterases, which indicated that this enzyme exhibits a characteristic Gly-Asp-Ser-(Leu) motif located close to the N-terminus and is harboring the catalytically active serine residue.	Glycine	201-204	DF17_RS11515	Streptomyces rimosus	109-115
12083943-12	2002	More recent investigations have focused on the two common polymorphisms of the beta(1)-adrenoceptor: Ser(49)--&gt;Gly, and Arg(389)--&gt;Gly.	Glycine	114-117	adrenoceptor beta 1	Homo sapiens	79-99
12083943-12	2002	More recent investigations have focused on the two common polymorphisms of the beta(1)-adrenoceptor: Ser(49)--&gt;Gly, and Arg(389)--&gt;Gly.	Glycine	137-140	adrenoceptor beta 1	Homo sapiens	79-99
17548045-4	2007	The CD23-based substrate, Dabcyl-His-Gly-Asp-Gln-Met-Ala-Gln-Lys-Ser-Lys(Fam)-NH2, is more selective, being hydrolyzed efficiently only by ADAM8 and ADAM10.	Glycine	37-40	ADAM metallopeptidase domain 10	Homo sapiens	149-155
15522297-4	2004	Purified MPP from potato processed two carrier proteins to an intermediate size, this processing was sensitive to an MPP inhibitor (1,10-phenanthroline) and further, processing could be inhibited by changing arginine residues to glycine residues at a -3 arginine consensus processing site for MPP.	Glycine	229-236	probable mitochondrial-processing peptidase subunit beta-like	Solanum tuberosum	9-12
17456474-3	2007	Murine aortic endothelial (MAE) cells interact via alpha(v) integrins with the integrin-binding Arg-Gly-Asp OPN sequence and adhere to immobilized OPN.	Glycine	100-103	secreted phosphoprotein 1	Mus musculus	108-111
15377998-2	2004	Here, we report a mutation of glycine to aspartic acid at the second glycine of the GXGXXG motif of Tie2 (G833DTie2) in human intramuscular haemangiomas (IMHs) of the capillary type.	Glycine	30-37	TEK receptor tyrosine kinase	Homo sapiens	100-104
15377998-2	2004	Here, we report a mutation of glycine to aspartic acid at the second glycine of the GXGXXG motif of Tie2 (G833DTie2) in human intramuscular haemangiomas (IMHs) of the capillary type.	Glycine	69-76	TEK receptor tyrosine kinase	Homo sapiens	100-104
15198928-6	2004	Gly-BSA-treated cells enhanced Smad2 and Smad3 protein levels 2.5 times the control levels in the nuclei.	Glycine	0-3	SMAD family member 2	Homo sapiens	31-36
15198928-6	2004	Gly-BSA-treated cells enhanced Smad2 and Smad3 protein levels 2.5 times the control levels in the nuclei.	Glycine	0-3	SMAD family member 3	Homo sapiens	41-46
15198928-7	2004	An electrophoretic mobility shift assay performed using CAGA sequences as a probe showed that Gly-BSA increased DNA/protein complexes.	Glycine	94-97	S100 calcium binding protein A8	Homo sapiens	56-60
15198928-10	2004	Transfection of phosphorothioate CAGA oligonucleotide, a CAGA antisense analog, inhibited Gly-BSA-induced PAI-1 mRNA expression.	Glycine	90-93	S100 calcium binding protein A8	Homo sapiens	33-37
12207158-6	2002	RESULTS: When the Pro(39) residue of IFN-alpha, which is located close to the Tyr(122) residue in the tertiary structure, was mutated to Gly, the analgesic activity of this mutant was lost completely, but the antiviral activity of IFN-alpha was maintained compared with wild-type IFN-alpha.	Glycine	137-140	interferon alpha 2	Homo sapiens	37-46
12207158-6	2002	RESULTS: When the Pro(39) residue of IFN-alpha, which is located close to the Tyr(122) residue in the tertiary structure, was mutated to Gly, the analgesic activity of this mutant was lost completely, but the antiviral activity of IFN-alpha was maintained compared with wild-type IFN-alpha.	Glycine	137-140	interferon alpha 2	Homo sapiens	231-240
12207158-6	2002	RESULTS: When the Pro(39) residue of IFN-alpha, which is located close to the Tyr(122) residue in the tertiary structure, was mutated to Gly, the analgesic activity of this mutant was lost completely, but the antiviral activity of IFN-alpha was maintained compared with wild-type IFN-alpha.	Glycine	137-140	interferon alpha 2	Homo sapiens	231-240
15198928-10	2004	Transfection of phosphorothioate CAGA oligonucleotide, a CAGA antisense analog, inhibited Gly-BSA-induced PAI-1 mRNA expression.	Glycine	90-93	S100 calcium binding protein A8	Homo sapiens	57-61
15198928-11	2004	Cotransfection of phosphorothioate CAGA oligonucleotides with PAI-1 reporter vector also blocked Gly-BSA-induced PAI-1 promoter luciferase activity.	Glycine	97-100	S100 calcium binding protein A8	Homo sapiens	35-39
17456474-3	2007	Murine aortic endothelial (MAE) cells interact via alpha(v) integrins with the integrin-binding Arg-Gly-Asp OPN sequence and adhere to immobilized OPN.	Glycine	100-103	secreted phosphoprotein 1	Mus musculus	147-150
17579066-7	2007	Characterization of this motif using site-directed mutagenesis reveals that a lysine residue in the X position of the Gly-X-Y collagen repeat, Lys(56) in ficolin-A, which is present in all ficolins and MBLs known to activate complement, is essential for MASP-2 binding.	Glycine	118-121	ficolin A	Rattus norvegicus	154-163
15198928-12	2004	These results indicate that Gly-BSA increases DNA binding activity of Smad3 and that it stimulates PAI-1 transcription through Smad-binding CAGA sequences in the PAI-1 promoter in HMC.	Glycine	28-31	SMAD family member 3	Homo sapiens	70-75
15198928-12	2004	These results indicate that Gly-BSA increases DNA binding activity of Smad3 and that it stimulates PAI-1 transcription through Smad-binding CAGA sequences in the PAI-1 promoter in HMC.	Glycine	28-31	S100 calcium binding protein A8	Homo sapiens	140-144
15247212-8	2004	Alanine-scanning mutagenesis of the GLUT4 amino terminus demonstrated that Phe(5) and Ile(8) within the FQQI motif and, to a lesser extent, Asp(12)/Gly(13) were necessary for the appropriate initial trafficking following biosynthesis.	Glycine	148-151	solute carrier family 2 member 4	Homo sapiens	36-41
11741585-0	2001	Domain IVa of laminin alpha5 chain is cell-adhesive and binds beta1 and alphaVbeta3 integrins through Arg-Gly-Asp.	Glycine	106-109	laminin, alpha 5	Mus musculus	14-28
11567025-9	2001	Using site-directed mutagenesis experiments, we identified Gly(149) of the GSVIA sequence in epithin as required for the processing and release of the protein.	Glycine	59-62	suppression of tumorigenicity 14 (colon carcinoma)	Mus musculus	93-100
11567025-10	2001	These results suggest that N-terminal processing of epithin at Gly(149) is a necessary prerequisite step for release of the protein.	Glycine	63-66	suppression of tumorigenicity 14 (colon carcinoma)	Mus musculus	52-59
17579066-7	2007	Characterization of this motif using site-directed mutagenesis reveals that a lysine residue in the X position of the Gly-X-Y collagen repeat, Lys(56) in ficolin-A, which is present in all ficolins and MBLs known to activate complement, is essential for MASP-2 binding.	Glycine	118-121	MBL associated serine protease 2	Rattus norvegicus	254-260
15226270-7	2004	Furthermore, alanine scanning of the linker region demonstrated that the Phe(732), Leu(742) and Gly(743) in the TLR3 cytoplasmic linker region are essential for ligand-induced NF-kappaB and IFN-beta promoter activation.	Glycine	96-99	toll like receptor 3	Homo sapiens	112-116
15226270-7	2004	Furthermore, alanine scanning of the linker region demonstrated that the Phe(732), Leu(742) and Gly(743) in the TLR3 cytoplasmic linker region are essential for ligand-induced NF-kappaB and IFN-beta promoter activation.	Glycine	96-99	interferon beta 1	Homo sapiens	190-198
17412895-5	2007	We transduced CX3CL1 (fractalkine), an immunostimulatory chemokine, to the mouse MSCs ex vivo using an adenoviral vector with the Arg-Gly-Asp-4C peptide in the fiber knob.	Glycine	134-137	chemokine (C-X3-C motif) ligand 1	Mus musculus	14-20
15228603-1	2004	A few naturally occurring insect tachykinin-related peptides, such as stomoxytachykinin (Stc-TK), contain an Ala-residue instead of the highly conserved Gly-residue that is present in most other members of this peptide family.	Glycine	153-156	Tachykinin	Drosophila melanogaster	33-43
11602754-7	2001	We propose that the high degree of sequence conservation at Gly-572 and Arg-579 may result from selective pressures imposed by prefusogenic conformations of the HIV-1 envelope glycoprotein.	Glycine	60-63	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	167-188
11489887-4	2001	The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins.	Glycine	226-233	SUMO specific peptidase 2	Homo sapiens	4-11
17276019-8	2007	Here we show that substitutions of glycine at 171 to K, F, I and Q also resulted in HBM-like activity in the presence of Wnt1 and Dkk1.	Glycine	35-42	dickkopf WNT signaling pathway inhibitor 1	Homo sapiens	130-134
11489887-4	2001	The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins.	Glycine	226-233	small ubiquitin like modifier 1	Homo sapiens	55-61
11489887-4	2001	The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins.	Glycine	226-233	small ubiquitin like modifier 1	Homo sapiens	86-92
15268194-9	2004	Comparisons of the relative energies of the four (+1)-charged glycine species show that doublet-state glycine III ((2)GlyIII1) is more stable in energy by 12.1 kcal/mol than the (+1)-charged glycine Gly ((2)Gly1).	Glycine	102-109	threonine aldolase 1, pseudogene	Homo sapiens	207-211
15268194-9	2004	Comparisons of the relative energies of the four (+1)-charged glycine species show that doublet-state glycine III ((2)GlyIII1) is more stable in energy by 12.1 kcal/mol than the (+1)-charged glycine Gly ((2)Gly1).	Glycine	118-121	threonine aldolase 1, pseudogene	Homo sapiens	207-211
17429808-1	2007	RGDS (Arg-Gly-Asp-Ser) is immobilized on poly(L-lactic acid) (PLLA) with ozone oxidation and the addition of an intermediate reactant, acryl succinimide (ASI) to promote the grafting efficiency.	Glycine	10-13	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	0-4
17445224-1	2007	Activation of the glycine modulatory site of the N-methyl-D-aspartate glutamate receptor (NMDAR) may reduce cognitive impairments associated with normal ageing.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	49-88
15161980-2	2004	The sumoylation reaction is catalyzed by the SUMO protease, which exposes the C-terminal active glycine residue of the nascent SUMO, the heterodimeric SUMO activating enzyme, the SUMO conjugating enzyme, Ubc9, and SUMO protein ligases, in a manner similar to ubiquitinylation.	Glycine	96-103	ubiquitin conjugating enzyme E2 I	Homo sapiens	204-208
11675599-3	2001	According to the consensus chronology, the pair of complementary GGC and GCC codons for the amino acids alanine and glycine appeared first.	Glycine	116-123	guanylate cyclase 2C	Homo sapiens	73-76
17445224-1	2007	Activation of the glycine modulatory site of the N-methyl-D-aspartate glutamate receptor (NMDAR) may reduce cognitive impairments associated with normal ageing.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	90-95
11562427-7	2001	A 9- to 39-fold increase in the alpha(2A)-AR agonist equilibrium dissociation constants further reflected changes in the G(alpha) protein-induced alpha(2A)-AR state mediated by the specific Gly to Glu mutation in the C-terminal portion of the G(alpha o) protein.	Glycine	190-193	G protein subunit alpha o1	Homo sapiens	243-252
17445224-9	2007	In summary, our results indicate that the facilitation of NMDAR activation through its glycine-binding site rescues the age-related deficit of cellular mechanisms of learning and memory.	Glycine	87-94	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	58-63
15165181-3	2004	The sequence of ZmDRH1 includes the eight RNA helicase motifs and two glycine-rich regions with arginine-glycine-rich (RGG) boxes at the amino (N)- and carboxy (C)-termini of the protein.	Glycine	70-77	DEAD box RNA helicase 1	Zea mays	16-22
15165181-3	2004	The sequence of ZmDRH1 includes the eight RNA helicase motifs and two glycine-rich regions with arginine-glycine-rich (RGG) boxes at the amino (N)- and carboxy (C)-termini of the protein.	Glycine	105-112	DEAD box RNA helicase 1	Zea mays	16-22
17188389-0	2007	Role of p38 map kinase in glycine-induced hepatocyte resistance to hypoxic injury.	Glycine	26-33	mitogen activated protein kinase 14	Rattus norvegicus	8-11
17188389-5	2007	Glycine protection required the activation of a signal pathway involving Src, Pyk2 and p38 MAP kinases.	Glycine	0-7	mitogen activated protein kinase 14	Rattus norvegicus	87-90
17227770-3	2007	Ser-116 --&gt; Gly (PED(S116G)) but not Ser-104 --&gt; Gly (PED(S104G)) substitution almost completely abolished TPA regulation of PED/PEA-15 expression.	Glycine	15-18	OCA2 melanosomal transmembrane protein	Homo sapiens	20-23
15133164-0	2004	Activation and inhibition of cyclin-dependent kinase-2 by phosphorylation; a molecular dynamics study reveals the functional importance of the glycine-rich loop.	Glycine	143-150	cyclin dependent kinase 2	Homo sapiens	29-54
15082791-5	2004	The rpb2 suppressor encodes a glycine-369 --&gt; serine (G369S) replacement, located in the "lobe" domain of Rpb2 and near the Rpb9 subunit, which was identified previously as an effector of start site selection.	Glycine	30-37	DNA-directed RNA polymerase II core subunit RPB9	Saccharomyces cerevisiae S288C	127-131
11514347-6	2001	Functional analysis of potential OPN interactions with conceptus and endometrial integrins was performed on LE and Tr cells in vitro using beads coated with OPN, poly-L-lysine, or recombinant OPN in which the Arg-Gly-Asp sequence was replaced with RGE or RAD.	Glycine	213-216	osteopontin	Ovis aries	33-36
11793249-6	2001	We note, however, that canine KRT2p encodes a protein 21 residues longer than human K2p due to the insertion of a glycine repeat motif, GG(G)X, in the head and tail domains of the canine gene.	Glycine	114-121	keratin 2	Canis lupus familiaris	30-35
17138865-3	2007	The final step in the biosynthesis of SP and CGRP is the conversion of their glycine-extended precursors to the active amidated peptide, and this process is catalyzed by sequential action of the enzymes peptidylglycine alpha-monooxygenase (PAM) and peptidylamidoglycolate lyase.	Glycine	77-84	calcitonin-related polypeptide alpha	Rattus norvegicus	45-49
11522251-1	2001	Four totally conserved glycines are involved in the packing of the two cytochrome b hemes, b(L) and b(H), of the bc(1) complex.	Glycine	23-31	cytochrome b	Saccharomyces cerevisiae S288C	71-83
15064403-6	2004	NKD2 is myristoylated on glycine, the second residue.	Glycine	25-32	NKD inhibitor of WNT signaling pathway 2	Canis lupus familiaris	0-4
17084840-6	2007	RESULTS: The FGFR4 Arg(388) allele was detected in 42.5% of the tumors (37% heterozygous Gly/Arg and 5.5% homozygous Arg/Arg).	Glycine	89-92	fibroblast growth factor receptor 4	Homo sapiens	13-18
15003013-1	2004	In this study, specific interactions between immobilized RGDS (Arg-Gly-Asp-Ser) cell adhesion peptides and cell integrin receptors located on cell membranes are controlled in vitro using stimuli-responsive polymer surface chemistry.	Glycine	67-70	ral guanine nucleotide dissociation stimulator	Homo sapiens	57-61
14960371-5	2004	NR1 prefers smaller ligands (glycine, serine, and alanine) in comparison with GluRB and GluR0 that bind l-glutamate: the bulky side chain of W731 in NR1 dramatically reduces the size of the ligand-binding site, functioning to selectively restrict recognition to glycine and the d-isomers of serine and alanine.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	0-3
15037197-0	2004	Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.	Glycine	0-7	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	57-62
15037197-7	2004	This difference in inhibition potency is substantially dependent on the difference in amino acid at position 154 in hENT1 (glycine) and hENT2 (serine).	Glycine	123-130	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	116-121
11543851-7	2001	GnRH-I pGlu-His-Trp-Ser-Try-Gly-Leu-Arg-Pro-Gly-NH2 and 2.	Glycine	28-31	gonadotropin releasing hormone 2	Homo sapiens	0-4
11543851-7	2001	GnRH-I pGlu-His-Trp-Ser-Try-Gly-Leu-Arg-Pro-Gly-NH2 and 2.	Glycine	44-47	gonadotropin releasing hormone 2	Homo sapiens	0-4
11543851-8	2001	GnRH-II pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2.	Glycine	29-32	gonadotropin releasing hormone 2	Homo sapiens	0-7
17568976-4	2007	A Kir1.1 channel where the site equivalent to E224 in the Kir2.1 channel is a glycine residue does not show inward rectification or single-channel fluctuations.	Glycine	78-85	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	2-8
11543851-8	2001	GnRH-II pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2.	Glycine	45-48	gonadotropin releasing hormone 2	Homo sapiens	0-7
11505268-5	2001	RESULTS: The results showed that the APC gene of explant cultured cells from OSF patients (8/8) had a CGA-to-GGA transition mutation at codon 498 that resulted in an Arg-to-Gly missense mutation (P &lt;.01).	Glycine	173-176	APC regulator of WNT signaling pathway	Homo sapiens	37-40
11457520-11	2001	The results demonstrate that these cell lines which express PC5 and not PC1 or PC2 have the ability to process pro-CCK into intermediate, glycine-extended forms more closely resembling pro-CCK products in intestine than in brain.	Glycine	138-145	proprotein convertase subtilisin/kexin type 5	Homo sapiens	60-63
14662146-7	2004	The folic acid+glycine supplement tended (P&lt;0.07) to increase allantoic content of PGE2 and TGF-beta2 in all sows and increased (P&lt;0.05) endometrial expression of COX2, especially in NYL sows.	Glycine	15-22	cytochrome c oxidase subunit II	Sus scrofa	169-173
14662146-13	2004	Finally, in YL and NYL sows, folic acid+glycine supplement decreased (P&lt;0.05) the endometrial expression of GM-CSF but not in ML sows.	Glycine	40-47	colony stimulating factor 2	Sus scrofa	111-117
14662146-14	2004	In summary, folic acid+glycine supplement altered endometrial expression of GM-CSF and uterine metabolism of prostaglandins during the post-attachment period of porcine embryos but some of these effects were manifest only in Meishan and nulliparous sows.	Glycine	23-30	colony stimulating factor 2	Sus scrofa	76-82
14675166-5	2004	Incubation of a GlyT2 N-terminal fusion protein with spinal cord extract in the presence of calcium followed by protein sequence analysis localized the major N-terminal cleavage site after methionine 156, with a second cleavage site being situated after glycine 164.	Glycine	254-261	solute carrier family 6 member 5	Homo sapiens	16-21
17568976-4	2007	A Kir1.1 channel where the site equivalent to E224 in the Kir2.1 channel is a glycine residue does not show inward rectification or single-channel fluctuations.	Glycine	78-85	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	58-64
17090548-6	2007	The subunits constituting PF4 form a tetrahedron having at its corners a RPRH motif that mimics (in reverse orientation) the Gly-His-Arg-Pro-amide peptides that co-crystallize with fibrin.	Glycine	125-128	platelet factor 4	Homo sapiens	26-29
14601095-1	2003	BACKGROUND: A recent study revealed that single nucleotide polymorphism (SNP) at codon 388 (Gly or Arg) of fibroblast growth factor receptor 4 (FGFR4) was associated with prognosis in patients with carcinoma of the breast and colorectal carcinoma.	Glycine	92-95	fibroblast growth factor receptor 4	Homo sapiens	107-142
14601095-1	2003	BACKGROUND: A recent study revealed that single nucleotide polymorphism (SNP) at codon 388 (Gly or Arg) of fibroblast growth factor receptor 4 (FGFR4) was associated with prognosis in patients with carcinoma of the breast and colorectal carcinoma.	Glycine	92-95	fibroblast growth factor receptor 4	Homo sapiens	144-149
11342552-9	2001	The mutation of Gly-89 in HPR produced no change in the sensitivity of HPR for RI, whereas it has been reported that mutating the equivalent residue Gly-88 in RNase A yielded a variant with increased RI resistance and cytotoxicity.	Glycine	149-152	ribonuclease A family member 1, pancreatic	Homo sapiens	159-166
17047094-0	2007	Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	71-74
11459447-3	2001	The conjugate dGp(NHCH(2)CH(2)S-Ac-Gly-Ser-Gly-OH)G was made by coupling the peptide, ClAc-Gly-Ser-Gly-OH, and dinucleotide, dGp(NHCH(2)CH(2)SH)G, through a thioether moiety.	Glycine	35-38	collagen type XXV alpha 1 chain	Homo sapiens	86-90
17047094-1	2007	N-Methyl-D-aspartate receptors (NMDARs) composed of NR1 and NR3 subunits differ from other NMDAR subtypes in that they require glycine alone for activation.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	60-63
11459447-3	2001	The conjugate dGp(NHCH(2)CH(2)S-Ac-Gly-Ser-Gly-OH)G was made by coupling the peptide, ClAc-Gly-Ser-Gly-OH, and dinucleotide, dGp(NHCH(2)CH(2)SH)G, through a thioether moiety.	Glycine	43-46	collagen type XXV alpha 1 chain	Homo sapiens	86-90
11459447-3	2001	The conjugate dGp(NHCH(2)CH(2)S-Ac-Gly-Ser-Gly-OH)G was made by coupling the peptide, ClAc-Gly-Ser-Gly-OH, and dinucleotide, dGp(NHCH(2)CH(2)SH)G, through a thioether moiety.	Glycine	43-46	collagen type XXV alpha 1 chain	Homo sapiens	86-90
17047094-6	2007	Ligand studies of NR1/NR3 receptors also suggest differential agonist selectivity between NR3 and NR1, as some high-affinity NR1 agonists only minimally activate NR1/NR3 receptors, whereas other NR1 agonists are as potent as glycine.	Glycine	225-232	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	90-93
12892754-5	2003	Site-directed mutagenesis of this region showed that Gly(182), Phe(186) and Gly(187) are required for maximum affinity, suggesting that the GTP-binding motif is G-N-x-x-[FM]-G. CE cloned from Drosophila CNS possessed a similar C-terminal sequence and also bound and hydrolyzed GTP.	Glycine	53-56	Sarcoplasmic calcium-binding protein 2	Drosophila melanogaster	177-179
12892754-5	2003	Site-directed mutagenesis of this region showed that Gly(182), Phe(186) and Gly(187) are required for maximum affinity, suggesting that the GTP-binding motif is G-N-x-x-[FM]-G. CE cloned from Drosophila CNS possessed a similar C-terminal sequence and also bound and hydrolyzed GTP.	Glycine	76-79	Sarcoplasmic calcium-binding protein 2	Drosophila melanogaster	177-179
17047094-6	2007	Ligand studies of NR1/NR3 receptors also suggest differential agonist selectivity between NR3 and NR1, as some high-affinity NR1 agonists only minimally activate NR1/NR3 receptors, whereas other NR1 agonists are as potent as glycine.	Glycine	225-232	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	90-93
17038321-2	2006	In high voltage-activated (HVA) Ca(V) channels, the mid-S6 glycine residue is only present in IS6 and IIS6, corresponding to G422 and G770 in Ca(V)1.2.	Glycine	59-66	immunoglobulin lambda variable 2-8	Homo sapiens	142-150
12740394-8	2003	The essential site for the distinct post-translation modification of MAP1LC3B is Lys-122 rather than the conserved Gly-120.	Glycine	115-118	microtubule associated protein 1 light chain 3 beta	Homo sapiens	69-77
11381078-0	2001	Inhibition of beta(2) integrin-mediated leukocyte cell adhesion by leucine-leucine-glycine motif-containing peptides.	Glycine	83-90	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	14-21
17038321-3	2006	Two additional glycine residues are found in the distal portion of IS6 (Gly(432) and Gly(436) in Ca(V)1.2) to form a triglycine motif unique to HVA Ca(V) channels.	Glycine	15-22	immunoglobulin lambda variable 2-8	Homo sapiens	97-105
11278707-5	2001	We found that, under conditions that stimulate vesicular glycine release, GLYT2 is rapidly trafficked first toward the plasma membrane and then internalized.	Glycine	57-64	solute carrier family 6 member 5	Homo sapiens	74-79
17038321-3	2006	Two additional glycine residues are found in the distal portion of IS6 (Gly(432) and Gly(436) in Ca(V)1.2) to form a triglycine motif unique to HVA Ca(V) channels.	Glycine	85-88	immunoglobulin lambda variable 2-8	Homo sapiens	97-105
16990281-5	2006	Here, by enzymatic footprints, we demonstrate the presence of several heterogeneous nuclear ribonucleoprotein (hnRNP) A1-binding sites on SLS3 and show the importance of the C-terminal Gly domain of hnRNP A1 in the formation of stable complexes containing several hnRNP A1 molecules bound on SLS3.	Glycine	185-188	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	199-207
11377199-11	2001	The general flexibility observed for the glycine loop and subtle changes to the phosphate binding site suggest a need to study interactions between inhibitors and active CDK2 in structure-based drug design programs.	Glycine	41-48	cyclin dependent kinase 2	Homo sapiens	170-174
11302743-3	2001	Here, we constructed a mutant by substituting the N-terminal glycine of Pr55(gag) with alanine to demonstrate that N-myristoylation of Pr55(gag) is required for efficient env protein transportation to the cell surface.	Glycine	61-68	Pr55(Gag)	Human immunodeficiency virus 1	77-80
12851615-3	2003	Recently, a common polymorphism has been identified at amino acid position 389 (Arg or Gly) of the human ADRB1, within a region important for receptor-Gs protein coupling and subsequent agonist-stimulated adenylyl cyclase activation.	Glycine	87-90	adrenoceptor beta 1	Homo sapiens	105-110
12944372-10	2003	Besides, another naturally occurring TNSALP with a Glu(218)--&gt;Gly mutation was also found to be polyubiquitinated and degraded in the proteasome.	Glycine	65-68	alkaline phosphatase, biomineralization associated	Homo sapiens	37-43
16982687-4	2006	Analysis of over 40 mutant receptors established that two large domains in the membrane-proximal region, which include the previously defined Box1 and Box2 domains as well as a highly conserved glycine among cytokine receptors, are required for Jak2 binding and activation and to sustain biological activity of the receptor.	Glycine	194-201	Janus kinase 2	Homo sapiens	245-249
12514178-1	2003	Cytoplasmic serine hydroxymethyltransferase (cSHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	192-199	pyridoxal phosphatase	Homo sapiens	90-93
11302743-3	2001	Here, we constructed a mutant by substituting the N-terminal glycine of Pr55(gag) with alanine to demonstrate that N-myristoylation of Pr55(gag) is required for efficient env protein transportation to the cell surface.	Glycine	61-68	Pr55(Gag)	Human immunodeficiency virus 1	140-143
17085797-14	2006	With long-acting beta2-agonists, the overall clinical benefits may be worse for Arg-16 than for the Gly-16 genotype.	Glycine	100-103	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	17-22
12482850-4	2003	Because the Crp4 NH(2) terminus occurs at Gly(61), not Leu(59), MMP-7 is necessary but insufficient to complete the processing of Crp4.	Glycine	42-45	defensin, alpha, 4	Mus musculus	12-16
16527444-2	2006	We found that SNL glycoprotein consists of carbohydrate content (69.74%) and protein content (30.26%), which contains more than 50% hydrophobic amino acids such as glycine and proline.	Glycine	164-171	fascin actin-bundling protein 1	Homo sapiens	14-17
12509873-5	2003	At least three nonoverlapping subpopulations of mAb210 glycine-immunoreactive cells can be distinguished with antibodies against calretinin, calbindin, and gamma-aminobutyric acid (GABA)(A) receptors.	Glycine	55-62	calbindin	Oryctolagus cuniculus	141-150
11294654-1	2001	Galectin-3, a beta-galactoside binding protein, contains a C-terminal carbohydrate recognition domain (CRD) and an N-terminal domain that includes several repeats of a proline-tyrosine-glycine-rich motif.	Glycine	185-192	galectin 3	Homo sapiens	0-10
11134053-1	2001	Human chorionic gonadotropin (hCG) is a heterodimeric member of a family of cystine knot-containing proteins that contain the consensus sequences Cys-X(1)-Gly-X(2)-Cys and Cys-X(3)-Cys.	Glycine	155-158	glycoprotein hormones, alpha polypeptide	Homo sapiens	6-34
16870514-4	2006	The relative positions of the glycine residues, i.e., Gly57 in hCathA, Gly53 in CPW, and Gly47 in beta5/PRE2, present in the oxyanion hole of each enzyme were also highly conserved.	Glycine	30-37	proteasome core particle subunit beta 5	Saccharomyces cerevisiae S288C	104-108
11337935-2	2001	Recently, a polymorphism of the beta 1-adrenoceptor has been detected: at amino acid position 389 either Gly or Arg has been found with the Gly389 exhibiting reduced responsiveness upon agonist-induced stimulation in vitro.	Glycine	105-108	adrenoceptor beta 1	Homo sapiens	32-51
12500216-2	2003	Sequence analysis of the polymerase chain reaction (PCR)-amplified gnomic DNA identified a missense mutation at nucleotide 451 of the von Hippel-Lindau (VHL) gene (A451G) that changes a codon for serine (AGT) to one for glycine (GGT) at amino acid position 80 (S80G).	Glycine	220-227	von Hippel-Lindau tumor suppressor	Homo sapiens	134-151
16298104-7	2006	Mutational analysis of a non-canonical residue (glycine 24) in human PCP-2 GL1 provided evidence for heterogeneity in mechanisms of Galphai interactions with GoLoco motifs.	Glycine	48-55	G protein subunit alpha o1	Homo sapiens	132-139
12602945-9	2003	Furthermore, we deleted the serine/glycine repeat region in the serglycin core protein.	Glycine	35-42	serglycin	Rattus norvegicus	64-73
11346965-4	2001	The reduction in P-protein amount led to a decrease in the ability of leaf mitochondria to decarboxylate glycine.	Glycine	105-112	glycine dehydrogenase (decarboxylating), mitochondrial	Solanum tuberosum	17-26
16901932-6	2006	Moreover, while we confirm previous reports that alteration of the H3 residue, Gly 722 prevents RU486-mediated inhibition of the PR, we show that the corresponding substitution in the glucocorticoid receptor does not inhibit RU486-mediated receptor antagonism.	Glycine	79-82	progesterone receptor	Homo sapiens	129-131
11171996-3	2001	Myozenin is predicted to be a 32-kDa, globular protein with a central glycine-rich domain flanked by alpha-helical regions with no strong homologies to any known genes.	Glycine	70-77	myozenin 1	Homo sapiens	0-8
12384499-8	2002	With analogy to complement factor D, we suggest that this strand will maintain its non-productive conformation in mature GzmK, mainly due to the unusual residues Gly(215), Glu(219), and Val(94).	Glycine	162-165	complement factor D	Homo sapiens	16-35
12384499-8	2002	With analogy to complement factor D, we suggest that this strand will maintain its non-productive conformation in mature GzmK, mainly due to the unusual residues Gly(215), Glu(219), and Val(94).	Glycine	162-165	granzyme K	Homo sapiens	121-125
12388550-1	2002	PAX6 functions as a transcription factor and has two DNA-binding domains, a paired domain (PD) and a homeodomain (HD), joined by a glycine-rich linker and followed by a proline-serine-threonine-rich (PST) transactivation region at the C terminus.	Glycine	131-138	paired box 6	Homo sapiens	0-4
12388550-3	2002	In this report we described the functional analyses of patient missense mutations from the paired domain region of PAX6 and a paireddomain-less isoform (PD-less) of Pax6 that lacks the paired domain and part of the glycine-rich linker.	Glycine	215-222	paired box 6	Homo sapiens	165-169
11232563-4	2001	Affected individuals have a serine to glycine mutation within the casein kinase Iepsilon (CKIepsilon) binding region of hPER2, which causes hypophosphorylation by CKIepsilon in vitro.	Glycine	38-45	casein kinase 1 epsilon	Homo sapiens	66-88
11232563-4	2001	Affected individuals have a serine to glycine mutation within the casein kinase Iepsilon (CKIepsilon) binding region of hPER2, which causes hypophosphorylation by CKIepsilon in vitro.	Glycine	38-45	casein kinase 1 epsilon	Homo sapiens	90-100
16815334-7	2006	Our data reveal that editing to glycine reduces the self-assembly competence of this critical subunit and slows GluR2 maturation in the endoplasmic reticulum (ER).	Glycine	32-39	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	112-117
12244096-2	2002	The SMN protein is important in small nuclear ribonucleoprotein (snRNP) assembly and interacts with snRNP proteins via arginine/glycine-rich domains.	Glycine	128-135	survival of motor neuron 1, telomeric	Homo sapiens	4-7
12244096-6	2002	Furthermore, we find that either of the two arginine/glycine-rich domains of GAR1 can provide for interaction with SMN, but removal of both results in loss of the interaction.	Glycine	53-60	survival of motor neuron 1, telomeric	Homo sapiens	115-118
10991943-3	2000	A 44-kDa remnant of MT1-MMP, with an N terminus at Gly(285), is also present on the cell after autolytic shedding of the catalytic domain from the hemopexin carboxyl (C) domain, but its role in gelatinase A activation is unknown.	Glycine	51-54	matrix metallopeptidase 14	Homo sapiens	20-27
12239217-1	2002	Human bile acid-CoA:amino acid N-acyltransferase (hBAT), an enzyme catalyzing the conjugation of bile acids with the amino acids glycine or taurine has significant sequence homology with dienelactone hydrolases and other alpha/beta hydrolases.	Glycine	129-136	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	6-48
16775345-9	2006	In particular, the C-terminal portion of the protein (Met-135-Gly-248) is sufficient for membrane association and is enough to direct p29 to the TGN vesicles in the absence of other viral elements.	Glycine	62-65	SYF2 pre-mRNA splicing factor	Homo sapiens	134-137
12239217-1	2002	Human bile acid-CoA:amino acid N-acyltransferase (hBAT), an enzyme catalyzing the conjugation of bile acids with the amino acids glycine or taurine has significant sequence homology with dienelactone hydrolases and other alpha/beta hydrolases.	Glycine	129-136	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	50-54
16510163-7	2006	One peptide comprised of two discontinuous segments of ACE2 (a.a. 22-44 and 351-357) artificially linked together by glycine, exhibited a potent antiviral activity with IC50 of about 0.1 microM.	Glycine	117-124	angiotensin converting enzyme 2	Homo sapiens	55-59
12482029-6	2002	Conversion of W1020 to glycine (W1020G) similarly abolished Jak2 kinase activity.	Glycine	23-30	Janus kinase 2	Homo sapiens	60-64
12445460-4	2002	Both the N-terminal regulatory domain of annexin XI (Anx11N) and the ALG-2-binding domain of Alix/AIP1 are rich in Pro, Gly, Ala, Tyr and Gln.	Glycine	120-123	annexin A11	Homo sapiens	41-51
11085936-7	2000	Employing the PTEN Gly(129)--&gt;Glu mutant, which is selectively defective in lipid phosphatase activity, it was established that it is the lipid phosphatase activity that controls PKCdelta phosphorylation.	Glycine	19-22	protein kinase C delta	Homo sapiens	182-190
11508546-4	2000	Low concentrations of the amino acids serine, glycine as well as 5-methyltetrahydrofolate were found in plasma and CSF and were due to a deficiency of the enzyme 3-phosphoglycerate dehydrogenase (3-PGDH).	Glycine	46-53	phosphoglycerate dehydrogenase	Homo sapiens	162-194
16406204-4	2006	Incubation of ODN with PEP generated two products, i.e. ODN3-18 and ODN5-18 which resulted from cleavage of the Ala-Thr and Val-Gly peptide bonds.	Glycine	128-131	prolyl endopeptidase	Homo sapiens	23-26
11056541-0	2000	Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases.	Glycine	0-7	presenilin 1	Homo sapiens	28-40
12422153-2	2002	There are 2 common polymorphisms of the beta1AR gene that alter the encoded amino acids at positions 49 (Ser or Gly) and 389 (Gly or Arg) and alter receptor function in vitro.	Glycine	112-115	adrenoceptor beta 1	Homo sapiens	40-47
12422153-2	2002	There are 2 common polymorphisms of the beta1AR gene that alter the encoded amino acids at positions 49 (Ser or Gly) and 389 (Gly or Arg) and alter receptor function in vitro.	Glycine	126-129	adrenoceptor beta 1	Homo sapiens	40-47
16406204-7	2006	For all these peptides, cleavage of the Pro-Gly peptide bond by PEP was never observed, even after prolonged incubation times.	Glycine	44-47	prolyl endopeptidase	Homo sapiens	64-67
16637649-0	2006	The paradoxical thermodynamic basis for the interaction of ethylene glycol, glycine, and sarcosine chains with bovine carbonic anhydrase II: an unexpected manifestation of enthalpy/entropy compensation.	Glycine	76-83	carbonic anhydrase 2	Bos taurus	118-139
12431739-6	2002	The disc Ance also showed endopeptidic activity towards locust tachykinin-1 (LomTK-I) by cleaving the Gly-Val peptide bond, but this enzyme was not the sole endopeptidase activity associated with discs.	Glycine	102-105	Tachykinin	Drosophila melanogaster	63-75
11032800-3	2000	Circular dichroism spectroscopy of an N-terminal peptide, PrP(37-53), showed that the PPII helix is formed in aqueous buffer; as it also contains an Xaa-Pro-Gly consensus sequence, it may act as a substrate for the collagen-modifying enzyme prolyl 4-hydroxylase.	Glycine	157-160	prion protein	Mus musculus	58-61
11029402-9	2000	Recombinant human MMP-2 cleaved calcitonin gene-related peptide (CGRP) specifically at the Gly(14)-Leu(15) peptide bond and reduced the vasodilatory potency of CGRP by 20-fold.	Glycine	91-94	matrix metallopeptidase 2	Homo sapiens	18-23
16717433-2	2006	FPI-F mutants P(1) residues of which, Thr(29), were replaced with Glu, Phe, Gly, Leu, Met, and Arg, were prepared.	Glycine	76-79	fungal protease inhibitor F	Bombyx mori	0-5
12106775-3	2002	Thyrotropin (TSH) and corticosterone levels were measured in serum; TRH and TRH-gly concentrations were determined in hypothalamus, hippocampus, n.accumbens, frontal cortex and amygdala of dams and pups at 21 days after parturition.	Glycine	80-83	thyrotropin releasing hormone	Rattus norvegicus	76-79
10987847-1	2000	gamma-Aminobutyric acid (GABA) and glycine are stored into synaptic vesicles by a recently identified vesicular inhibitory amino acid transporter [VIAAT, also called vesicular GABA transporter (VGAT)].	Glycine	35-42	solute carrier family 32 member 1	Rattus norvegicus	102-145
12027806-5	2002	Site-specific mutagenesis pinpointed the need for glycine and serine residues in the cleavage sequence Leu-Ser-Lys-Gly-Ser-Ile-Val-Val, which is localized between the two epidermal-growth-factor-like motifs of the mucin.	Glycine	50-57	LOC100508689	Homo sapiens	214-219
16557226-7	2006	Pan-caspase and caspase-3 inhibitors reduced cellular death (necrosis and apoptosis) 24 h after Gly-ARF.	Glycine	96-99	caspase 3	Rattus norvegicus	16-25
12027806-5	2002	Site-specific mutagenesis pinpointed the need for glycine and serine residues in the cleavage sequence Leu-Ser-Lys-Gly-Ser-Ile-Val-Val, which is localized between the two epidermal-growth-factor-like motifs of the mucin.	Glycine	115-118	LOC100508689	Homo sapiens	214-219
12027806-6	2002	A similar cleavage sequence (Phe-Arg-Pro-Gly downward arrow Ser-Val-Val-Val, where downward arrow signifies the cleavage site) has been reported in human MUC1 and analogous sites are present in human MUC3, MUC12 and MUC17.	Glycine	41-44	mucin 1, cell surface associated	Homo sapiens	154-158
10987847-1	2000	gamma-Aminobutyric acid (GABA) and glycine are stored into synaptic vesicles by a recently identified vesicular inhibitory amino acid transporter [VIAAT, also called vesicular GABA transporter (VGAT)].	Glycine	35-42	solute carrier family 32 member 1	Rattus norvegicus	147-152
10987847-1	2000	gamma-Aminobutyric acid (GABA) and glycine are stored into synaptic vesicles by a recently identified vesicular inhibitory amino acid transporter [VIAAT, also called vesicular GABA transporter (VGAT)].	Glycine	35-42	solute carrier family 32 member 1	Rattus norvegicus	166-192
10987847-1	2000	gamma-Aminobutyric acid (GABA) and glycine are stored into synaptic vesicles by a recently identified vesicular inhibitory amino acid transporter [VIAAT, also called vesicular GABA transporter (VGAT)].	Glycine	35-42	solute carrier family 32 member 1	Rattus norvegicus	194-198
16632906-1	2006	The membrane-spanning domain (MSD) of HIV-1 envelope protein (Env) has an additional glycine residue within a well-conserved putative transmembrane helix-helix interaction motif, GXXXG, and forms a G(690)G(691)XXG(694) sequence (G, glycine; X, any residues; the numbering indicates the position within the Env of an infectious molecular clone, HXB2).	Glycine	232-239	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	44-60
10851237-4	2000	We show that unique carboxyl-terminal arginine- and glycine-rich domains comprising the last 29 amino acids of SmD1 and the last 32 amino acids of SmD3 are necessary and sufficient for SMN binding.	Glycine	52-59	small nuclear ribonucleoprotein D3 polypeptide	Homo sapiens	147-151
12221122-12	2002	This pinpointed glycine 156 within the catalytic motif as being responsible for the dual CDP-alcohol specificity of CEPT1, whereas mutations within helix 214-228 allowed for the orientation of transmembrane helices surrounding the catalytic site to be definitively positioned.	Glycine	16-23	choline/ethanolamine phosphotransferase 1	Homo sapiens	116-121
16632906-1	2006	The membrane-spanning domain (MSD) of HIV-1 envelope protein (Env) has an additional glycine residue within a well-conserved putative transmembrane helix-helix interaction motif, GXXXG, and forms a G(690)G(691)XXG(694) sequence (G, glycine; X, any residues; the numbering indicates the position within the Env of an infectious molecular clone, HXB2).	Glycine	232-239	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	62-65
12034720-0	2002	The myocardium-protective Gly-49 variant of the beta 1-adrenergic receptor exhibits constitutive activity and increased desensitization and down-regulation.	Glycine	26-29	adrenoceptor beta 1	Homo sapiens	48-74
16465388-4	2006	We identified the transactivation domain of Osterix, which contains high proline and glycine residues and has an activation property in mammalian and yeast cells.	Glycine	85-92	Sp7 transcription factor	Homo sapiens	44-51
12034720-2	2002	Patients with heart failure who were hetero- or homozygous for the Gly-49 variant of the beta(1)AR (Gly-49-beta(1)AR) showed improved long-term survival as compared with those with the Ser-49 genotype.	Glycine	67-70	adrenoceptor beta 1	Homo sapiens	89-98
12034720-2	2002	Patients with heart failure who were hetero- or homozygous for the Gly-49 variant of the beta(1)AR (Gly-49-beta(1)AR) showed improved long-term survival as compared with those with the Ser-49 genotype.	Glycine	67-70	adrenoceptor beta 1	Homo sapiens	100-116
12034720-10	2002	The stronger regulation of the Gly-49-beta(1)AR could explain the beneficial effect of the Gly-49 genotypes on survival, further supporting the concept that beta(1)AR desensitization is protective in heart failure.	Glycine	31-34	adrenoceptor beta 1	Homo sapiens	38-47
10926824-1	2000	We describe three mutations of the red-cell anion exchangerband 3 (AE1, SLC4A1) gene associated with distalrenal tubular acidosis (dRTA) in families from Malaysia and Papua NewGuinea: Gly(701)--&gt;Asp (G701D), Ala(858)--&gt;Asp(A858D) and deletion of Val(850) (DeltaV850).	Glycine	184-187	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	67-70
10926824-1	2000	We describe three mutations of the red-cell anion exchangerband 3 (AE1, SLC4A1) gene associated with distalrenal tubular acidosis (dRTA) in families from Malaysia and Papua NewGuinea: Gly(701)--&gt;Asp (G701D), Ala(858)--&gt;Asp(A858D) and deletion of Val(850) (DeltaV850).	Glycine	184-187	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	72-78
10880738-3	2000	We observed Vbeta4 clones sharing the Gly (G)-G motif in the CDR3 nDn regions and a Vbeta4-Jbeta2.7 combination in three patients bearing HLA-DR2 and -DQ1.	Glycine	38-41	necdin, MAGE family member	Homo sapiens	66-69
17028433-7	2006	In the glycine group we observed a tendency towards decreased apoptosis-related cell death measured by the activity of caspase-3 in liver tissue and the percentage of TUNEL-positive hepatocytes in comparison to the untreated group.	Glycine	7-14	caspase 3	Rattus norvegicus	119-128
12071967-4	2002	At the cDNA level, the C-terminus of the extracellular domain of human CNTF-R (amino acids 1-346) was linked via a single glycine residue to the N-terminus of human CNTF (amino acids 1-186).	Glycine	122-129	ciliary neurotrophic factor receptor	Homo sapiens	71-77
12068077-1	2002	Coexpression of PSD-95(c-Myc) with NR1-1a/NR2A NMDA receptors in human embryonic kidney (HEK) 293 cells resulted in a decrease in efficacy for the glycine stimulation of [3 H]MK801 binding similar to that previously described for l-glutamate.	Glycine	147-154	discs large MAGUK scaffold protein 4	Homo sapiens	16-22
17028433-9	2006	Liver tissue levels of tumor necrosis factor (TNF)alpha were reduced only in the glycine group whereas TNFalpha was increased in the untreated as well as the LA group.	Glycine	81-88	tumor necrosis factor-like	Rattus norvegicus	23-44
10886564-12	2000	However, different injury mechanisms were operative since (1) CE, but not CO, toxicity significantly altered cell phospholipid profiles, and (2) 2 mmol/L glycine completely blocked CE- but not CO-mediated cell death.	Glycine	154-161	carboxyl ester lipase	Mus musculus	181-183
16583127-5	2006	The mutation causes arginine to be replaced by glycine in codon 65 (R65G) in the juxtamembrane region of EDA.	Glycine	47-54	ectodysplasin A	Homo sapiens	105-108
16227627-2	2005	SYT has a conserved N-terminal domain (SNH domain) that interacts with the human paralog of Drosophila Brahma (hBRM) and Brahma-related gene 1 (BRG1) chromatin remodeling proteins and a C-terminal transactivating sequence rich in glutamine, proline, glycine, and tyrosine (QPGY domain).	Glycine	250-257	synaptotagmin 1	Homo sapiens	0-3
10799493-2	2000	Site-directed single substitution of each of these amino acids except glycines in the yeast MsrA resulted in total loss of enzyme activity.	Glycine	70-78	methionine sulfoxide reductase A	Bos taurus	92-96
10773584-2	2000	The aminoterminal segment, Arg(8)-Leu(9)-Val(10)-Gly(11) (RLVG), of the single polypeptide chain of cystatin C constitutes an essential part of its inhibitory center.	Glycine	49-52	cystatin C	Homo sapiens	100-110
10773584-8	2000	In contrast to wild-type cystatin C, recombinant human cystatin C with Gly substitutions for residues Arg(8), Leu(9), Val(10), and Trp(106), and with low or nonexistent affinity for cysteine proteinases, did not display any inhibitory effect on bone resorption.	Glycine	71-74	cystatin C	Homo sapiens	55-65
11880366-4	2002	These analyses ultimately identified Asp(149), Arg(151), Gly(207), Tyr(252), and Glu(258) as critical for NIF binding.	Glycine	57-60	S100 calcium binding protein A8	Homo sapiens	106-109
11982762-8	2002	Direct sequencing of the keratin 1 gene revealed a frameshift mutation in exon 9 that leads to the partial loss of the glycine loop motif in the V2 domain and the gain of a novel 70 amino acid peptide.	Glycine	119-126	keratin 1	Homo sapiens	25-34
16223757-0	2005	The neurotransmitters glycine and GABA stimulate glucagon-like peptide-1 release from the GLUTag cell line.	Glycine	22-29	glucagon	Mus musculus	49-72
16223757-10	2005	Glycine-triggered GLP-1 secretion was impaired by bumetanide but not bendrofluazide, suggesting that a high intracellular [Cl-] maintained by Na(+)-K(+)-2Cl- cotransporters is necessary for the depolarizing response to glycine receptor ligands.	Glycine	0-7	glucagon	Mus musculus	18-23
11854276-7	2002	First, among the six disulfide bonds, only SS1 in loop E (Gly(142)-Leu(155)) and SS6 in loop G (Ser(185)-Gly(197)) were necessary for the catalytic efficiency of neuropsin.	Glycine	58-61	opsin 5	Mus musculus	162-171
10806385-11	2000	In marked contrast, these analogues strongly and competitively inhibited the decarboxylation of the glycine molecule catalysed by the P-protein component of the glycine decarboxylase system.	Glycine	100-107	glycine decarboxylase	Homo sapiens	161-182
11854276-7	2002	First, among the six disulfide bonds, only SS1 in loop E (Gly(142)-Leu(155)) and SS6 in loop G (Ser(185)-Gly(197)) were necessary for the catalytic efficiency of neuropsin.	Glycine	105-108	opsin 5	Mus musculus	162-171
16388117-8	2005	In this patient, the occurrence of precocious puberty was thought to result from excessive stimulation by glycine of the NMDA receptors linked to the GnRH neurons.	Glycine	106-113	gonadotropin releasing hormone 1	Homo sapiens	150-154
11939795-0	2002	Contribution of regions distal to glycine-160 to the anticoagulant activity of tissue factor pathway inhibitor.	Glycine	34-41	tissue factor pathway inhibitor	Homo sapiens	79-110
11939795-13	2002	Together, the data indicate that the region between Gly-160 and the end of the third Kunitz domain contributes to TFPI function by orienting the second Kunitz domain so that it can bind the active site of phospholipid-associated factor Xa prior to prothrombinase assembly and/or by slowing formation of the prothrombinase complex.	Glycine	52-55	tissue factor pathway inhibitor	Homo sapiens	114-118
10810290-9	2000	In addition, fetal IGF-I infusion increased the conversion of serine to glycine which is likely to have increased the availability of one-carbon groups for biosynthesis.	Glycine	72-79	insulin-like growth factor I	Ovis aries	19-24
16129665-3	2005	To search for sequence determinants of murine (12R)-LOX, we carried out multiple amino acid sequence alignments and found that Phe(390), Gly(441), Ala(455), and Val(631) align with previously identified positional determinants of S-LOX isoforms.	Glycine	137-140	arachidonate 12-lipoxygenase, 12R type	Mus musculus	47-55
10865121-4	2000	The two isoforms of the mammalian vesicular monoamine transporter, VMAT1 and VMAT2, are related to the vesicular acetylcholine transporter (VACHT), while a novel, unrelated vesicular inhibitory amino acid transporter (VIAAT), also designated vesicular GABA transporter (VGAT), is responsible for the storage of GABA, glycine or, at some synapses, both amino acids into synaptic vesicles.	Glycine	317-324	solute carrier family 18 member A1	Homo sapiens	67-72
10865121-4	2000	The two isoforms of the mammalian vesicular monoamine transporter, VMAT1 and VMAT2, are related to the vesicular acetylcholine transporter (VACHT), while a novel, unrelated vesicular inhibitory amino acid transporter (VIAAT), also designated vesicular GABA transporter (VGAT), is responsible for the storage of GABA, glycine or, at some synapses, both amino acids into synaptic vesicles.	Glycine	317-324	solute carrier family 18 member A2	Homo sapiens	77-82
11799113-6	2002	Following transport to the acidified TGN/endosomal compartments, furin cleaves the bound propeptide at a second, internal P1/P6 Arg site (-Arg-Gly-Val(72)-Thr-Lys-Arg(75)-) resulting in propeptide dissociation and enzyme activation.	Glycine	143-146	furin, paired basic amino acid cleaving enzyme	Homo sapiens	65-70
16407782-2	2005	Galectin-3 is the only family member that is composed of a glycine/prolinerich N-terminal repeated sequence and a C-terminal carbohydrate-binding domain.Multiple functions of galectin-3 have been reported, depending on its location.	Glycine	59-66	galectin 3	Homo sapiens	0-10
11920851-5	2002	This mutation, which is predicted to cause a missense substitution of serine for glycine, occurred at codon 266 in exon 8 of PSEN1.	Glycine	81-88	presenilin 1	Homo sapiens	125-130
10887930-9	2000	The two transition mutations observed in the two families also predict the conversion of arginine to a stop codon (R203X and R240X, respectively) around the homeodomain (HD), leading to the truncation of the PAX6 protein within its glycine-rich region.	Glycine	232-239	paired box 6	Homo sapiens	208-212
10733886-2	2000	We have cloned the human cDNA Fhit in the pPROEX-1 vector and expressed with high yield in Escherichia coli with the sequence Met-Gly-His(6)-Asp-Tyr-Asp-Ile-Pro-Thr-Thr followed by a rTEV protease cleavage site, denoted as "H6TV," fused to the N-terminus of Fhit.	Glycine	130-133	fragile histidine triad diadenosine triphosphatase	Homo sapiens	30-34
11821404-1	2002	Previous work has demonstrated that the large subunit (rbcL) of ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCo) from wheat is cleaved at Gly-329 by the Fe(2+)/ascorbate/H(2)O(2) system (Ishida, H., Makino, A., and Mae, T. (1999) J. Biol.	Glycine	147-150	ribulose bisphosphate carboxylase large chain	Triticum aestivum	55-59
16407782-2	2005	Galectin-3 is the only family member that is composed of a glycine/prolinerich N-terminal repeated sequence and a C-terminal carbohydrate-binding domain.Multiple functions of galectin-3 have been reported, depending on its location.	Glycine	59-66	galectin 3	Homo sapiens	175-185
11821404-6	2002	Conformational analysis demonstrated that five of them are located in the alpha/beta-barrel, whereas Gly-122 is in the N-terminal domain but near the bound metal in the adjacent rbcL.	Glycine	101-104	ribulose bisphosphate carboxylase large chain	Triticum aestivum	178-182
16293771-10	2005	OPN significantly reduced the STZ-induced NO levels in the islets through an Arg-Gly-Asp (RGD)-dependent reduction of inducible NO synthase (iNOS) mRNA levels.	Glycine	81-84	secreted phosphoprotein 1	Rattus norvegicus	0-3
11930008-2	2002	Osteopontin (OPN) is an extracellular matrix protein containing Arg-Gly-Asp (RGD) sequence, which interacts with alpha(v)beta3 integrins, promotes cell attachment, and cell migration and is expressed in both synovial cells and chondrocytes in rheumatoid arthritis; however, its functional relationship to arthritis has not been known.	Glycine	68-71	secreted phosphoprotein 1	Mus musculus	0-11
16153125-7	2005	To encourage cell adhesion, PUs were surface-modified with radio frequency glow discharge followed by coupling of Arg-Gly-Asp-Ser (RGDS).	Glycine	118-121	ral guanine nucleotide dissociation stimulator	Homo sapiens	131-135
10705368-2	2000	The G50V mutation in the G protein alpha subunit (G(alpha)), Gpa1p, is analogous to the p21(ras) transforming mutation Gly--&gt;Val 12, and has been extensively examined for the phenotypes it produces in yeast cells.	Glycine	119-122	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	61-66
10677296-3	2000	In one family with OSMED, a homozygous Gly-->Arg substitution has been described in COL11A2, which codes for the alpha2 chain of type XI collagen.	Glycine	39-42	collagen type XI alpha 2 chain	Homo sapiens	84-91
16172230-8	2005	Maternal CYP1B1 (48)Gly homozygosity was associated with a 2.7-fold increased risk of TGCC (95% CI, 0.9-7.9), with little evidence that Leu(432)Val or Asn(453)Ser genotypes were related to risk.	Glycine	20-23	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	9-15
10808503-3	2000	Raclopride (D2 dopamine receptor antagonist) increased the glycine extracellular level in food intake.	Glycine	59-66	dopamine receptor D2	Rattus norvegicus	12-32
10620501-6	2000	A 12-residue spacer, Thr-Arg-His-Arg-Gln-Pro-Arg-Gly-Trp-Glu-Gln-Leu, containing the recognition site for the protease furin, was incorporated between the toxin and the ligand to generate restrictocin-spacer-anti-TFR(scFv) and anti-TFR(scFv)-spacer-restrictocin.	Glycine	49-52	furin, paired basic amino acid cleaving enzyme	Homo sapiens	119-124
16105886-9	2005	Another microtubule plus-end tracking protein, EB1, directly interacts with the CAP-Gly domain of CLIP-190 and is required to localise CLIP-190 at microtubule plus-ends.	Glycine	84-87	Eb1	Drosophila melanogaster	47-50
10625634-1	2000	Osteopontin (OPN) is a sialic acid-rich, adhesive, extracellular matrix (ECM) protein with Arg-Gly-Asp cell-binding sequence that interacts with several integrins, including alpha(v)beta(3).	Glycine	95-98	secreted phosphoprotein 1	Mus musculus	0-11
10625634-1	2000	Osteopontin (OPN) is a sialic acid-rich, adhesive, extracellular matrix (ECM) protein with Arg-Gly-Asp cell-binding sequence that interacts with several integrins, including alpha(v)beta(3).	Glycine	95-98	secreted phosphoprotein 1	Mus musculus	13-16
16105886-9	2005	Another microtubule plus-end tracking protein, EB1, directly interacts with the CAP-Gly domain of CLIP-190 and is required to localise CLIP-190 at microtubule plus-ends.	Glycine	84-87	Cytoplasmic linker protein 190	Drosophila melanogaster	98-106
10643802-2	2000	The role of the mutation E318G (a substitution of glutamic acid to glycine) in the PSEN-1 is controversial.	Glycine	67-74	presenilin 1	Homo sapiens	83-89
16105886-9	2005	Another microtubule plus-end tracking protein, EB1, directly interacts with the CAP-Gly domain of CLIP-190 and is required to localise CLIP-190 at microtubule plus-ends.	Glycine	84-87	Cytoplasmic linker protein 190	Drosophila melanogaster	135-143
15949923-3	2005	The spectrophotometric titration curve of RNase A upon interaction with SDS indicated a distinct complex intermediate in glycine buffer at pH 3.3.	Glycine	121-128	ribonuclease A family member 1, pancreatic	Homo sapiens	42-49
15603814-1	2005	Chitosan scaffolds were modified with RGDS (Arg-Gly-Asp-Ser) in the present work via an imide-bond forming reaction between amino groups in chitosan and carboxyl groups in peptides.	Glycine	48-51	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	38-42
15938724-1	2005	We describe haematological and DNA characterization of haemoglobinopathies in Thai adolescents caused by compound heterozygosities for Hb E [beta26(B8) Glu-Lys] and two other beta-globin chain variants, Hb Pyrgos [beta83(EF7) Gly-Asp] and Hb J Bangkok [beta56(D7) Gly-Asp].	Glycine	226-229	hemoglobin subunit epsilon 1	Homo sapiens	135-139
10651282-2	1999	Here, we focused on the structural role of the first CDR-H3 residue, and we selected two antibodies, 28B4 and PLG, whose CDR-H3 conformations are significantly different, having Trp and Gly at the first position, respectively.	Glycine	186-189	plasminogen	Homo sapiens	101-113
10559137-3	1999	The amino acid sequences in interstitial collagen (Gly-Leu/Ile) and laminin-5 (Ala-Leu) that are cleaved by MMP-2 are homologous to a region (Gly(32)-Leu(33)) within human big endothelin-1[1 to 38] (big ET-1).	Glycine	51-54	matrix metallopeptidase 2	Homo sapiens	108-113
10559137-3	1999	The amino acid sequences in interstitial collagen (Gly-Leu/Ile) and laminin-5 (Ala-Leu) that are cleaved by MMP-2 are homologous to a region (Gly(32)-Leu(33)) within human big endothelin-1[1 to 38] (big ET-1).	Glycine	142-145	matrix metallopeptidase 2	Homo sapiens	108-113
10559137-8	1999	Incubation of big ET-1 with recombinant human MMP-2 resulted in the specific cleavage of the Gly(32)-Leu(33) bond of big ET-1.	Glycine	93-96	matrix metallopeptidase 2	Homo sapiens	46-51
15938724-1	2005	We describe haematological and DNA characterization of haemoglobinopathies in Thai adolescents caused by compound heterozygosities for Hb E [beta26(B8) Glu-Lys] and two other beta-globin chain variants, Hb Pyrgos [beta83(EF7) Gly-Asp] and Hb J Bangkok [beta56(D7) Gly-Asp].	Glycine	264-267	hemoglobin subunit epsilon 1	Homo sapiens	135-139
10614823-6	1999	Residue 85 is encoded in the cDNA as a Ser residue, but plasma tetranectin is a 1:1 mixture of Ser85 and Gly-85 sequence variants.	Glycine	105-108	C-type lectin domain family 3 member B	Homo sapiens	63-74
15811074-6	2005	The critical codon (nucleotide 3216-3218) in all three clones for the HBD of sPR was found to encode for glycine.	Glycine	105-112	sepiapterin reductase	Homo sapiens	77-80
15644323-4	2005	Here, using an untranslated region-targeted RNA interference/rescue strategy in Drosophila Schneider 2 cells, we show that Aph-1 contributes to the assembly of the gamma-secretase complex by multiple mechanisms involving intermolecular and intramolecular interactions depending on or independent of the conserved glycines.	Glycine	313-321	anterior pharynx defective 1	Drosophila melanogaster	123-128
10531318-6	1999	In contrast, deletion of the MH2 domain or a point mutation of glycine 379 within this domain obliterated the self-stimulatory activity of Smad3, but not the inhibitory activity.	Glycine	63-70	SMAD family member 3	Homo sapiens	139-144
15837191-5	2005	These two domains, as well as the structurally unrelated ubiquitin binding motif UIM, provide a common, crucial recognition site for ubiquitin, comprising a hydrogen-bonding acceptor for the amide group of Gly-47, and a methyl group that packs against the hydrophobic pocket of ubiquitin formed by Leu-8, Ile-44, His-68, and Val-70.	Glycine	206-209	ubiquitin	Saccharomyces cerevisiae S288C	57-66
10493917-6	1999	The LIMK1 mutants with deleted LIM domains (DeltaLIM) or conserved cysteines in the two LIM domains replaced with glycines (dmLIMK1) had 3-7-fold higher kinase activities in vitro, compared with the wild-type LIMK1.	Glycine	114-122	LIM domain kinase 1	Homo sapiens	4-9
10493917-6	1999	The LIMK1 mutants with deleted LIM domains (DeltaLIM) or conserved cysteines in the two LIM domains replaced with glycines (dmLIMK1) had 3-7-fold higher kinase activities in vitro, compared with the wild-type LIMK1.	Glycine	114-122	PDZ and LIM domain 5	Homo sapiens	4-7
15837191-5	2005	These two domains, as well as the structurally unrelated ubiquitin binding motif UIM, provide a common, crucial recognition site for ubiquitin, comprising a hydrogen-bonding acceptor for the amide group of Gly-47, and a methyl group that packs against the hydrophobic pocket of ubiquitin formed by Leu-8, Ile-44, His-68, and Val-70.	Glycine	206-209	ubiquitin	Saccharomyces cerevisiae S288C	133-142
10493917-6	1999	The LIMK1 mutants with deleted LIM domains (DeltaLIM) or conserved cysteines in the two LIM domains replaced with glycines (dmLIMK1) had 3-7-fold higher kinase activities in vitro, compared with the wild-type LIMK1.	Glycine	114-122	LIM domain kinase 1	Homo sapiens	126-131
15837191-5	2005	These two domains, as well as the structurally unrelated ubiquitin binding motif UIM, provide a common, crucial recognition site for ubiquitin, comprising a hydrogen-bonding acceptor for the amide group of Gly-47, and a methyl group that packs against the hydrophobic pocket of ubiquitin formed by Leu-8, Ile-44, His-68, and Val-70.	Glycine	206-209	ubiquitin	Saccharomyces cerevisiae S288C	133-142
15833937-4	2005	Men with Gly/Gly genotypes for both the beta1 and beta2 receptors showed significant increases (approximately 0.6%/yr) in BMI from childhood to adulthood.	Glycine	9-12	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	50-55
10517806-14	1999	The majority of P1-4 neurones were depolarized by glycine ( approximately 80 %) and spikes were evoked in approximately 30 %.	Glycine	50-57	SUB1 regulator of transcription	Rattus norvegicus	16-20
15833937-4	2005	Men with Gly/Gly genotypes for both the beta1 and beta2 receptors showed significant increases (approximately 0.6%/yr) in BMI from childhood to adulthood.	Glycine	13-16	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	50-55
10571879-3	1999	On one hand, we observed a rapid glycine catabolism that involved glycine oxidation by the mitochondrial glycine decarboxylase (GDC) system.	Glycine	33-40	glycine decarboxylase	Homo sapiens	105-126
10571879-3	1999	On one hand, we observed a rapid glycine catabolism that involved glycine oxidation by the mitochondrial glycine decarboxylase (GDC) system.	Glycine	66-73	glycine decarboxylase	Homo sapiens	105-126
15689563-5	2005	Both GABA and glycine increased limb-innervating motoneuron activity and decreased respiratory motoneuron activity in wild-type mice, but only glycine responses were abolished in gephyrin-deficient mice.	Glycine	143-150	gephyrin	Mus musculus	179-187
15355958-2	2004	Since human Atg4B was found to cleave the carboxyl terminus of MAP1LC3B in vitro, we hypothesized that this exposes its carboxyl-terminal Gly(120).	Glycine	138-141	autophagy related 4B cysteine peptidase	Homo sapiens	12-17
10417756-6	1999	All mutations were missense changes within the GSK3beta consensus site, affecting serine residues at codons 33 and 37 and glycine at codon 34.	Glycine	122-129	glycogen synthase kinase 3 beta	Homo sapiens	47-55
10455185-5	1999	Analysis of the products of pro-ISG15 processing enzyme demonstrates specific cleavage exclusively at the Gly(157)-Gly(158) peptide bond to generate a mature ISG15 carboxyl terminus.	Glycine	106-109	ISG15 ubiquitin like modifier	Homo sapiens	32-37
10455185-5	1999	Analysis of the products of pro-ISG15 processing enzyme demonstrates specific cleavage exclusively at the Gly(157)-Gly(158) peptide bond to generate a mature ISG15 carboxyl terminus.	Glycine	106-109	ISG15 ubiquitin like modifier	Homo sapiens	158-163
10455185-5	1999	Analysis of the products of pro-ISG15 processing enzyme demonstrates specific cleavage exclusively at the Gly(157)-Gly(158) peptide bond to generate a mature ISG15 carboxyl terminus.	Glycine	115-118	ISG15 ubiquitin like modifier	Homo sapiens	32-37
12769627-4	2002	Inasmuch as agonists at the NMDA recognition site are excitotoxic, drugs acting via the co-agonist, glycine(B) (GLY(B)) site are more promising clinical candidates as antipsychotic agents.	Glycine	100-107	Glycine auxotroph B, complementation of hamster	Homo sapiens	112-118
15355958-2	2004	Since human Atg4B was found to cleave the carboxyl terminus of MAP1LC3B in vitro, we hypothesized that this exposes its carboxyl-terminal Gly(120).	Glycine	138-141	microtubule associated protein 1 light chain 3 beta	Homo sapiens	63-71
15355958-7	2004	To clarify this contradiction, we sought to determine whether the carboxyl terminus of MAP1LC3B is cleaved to expose Gly(120) for further ubiquitylation-like reactions.	Glycine	117-120	microtubule associated protein 1 light chain 3 beta	Homo sapiens	87-95
15355958-9	2004	An in vitro assay showed that Gly(120) is essential for carboxyl-terminal cleavage by human Atg4B as well as for formation of the intermediates Atg7-MAP1LC3B (ubiquitin-activating enzyme-substrate) and Atg3-MAP1LC3B (ubiquitin carrier protein-substrate).	Glycine	30-33	autophagy related 4B cysteine peptidase	Homo sapiens	92-97
15355958-9	2004	An in vitro assay showed that Gly(120) is essential for carboxyl-terminal cleavage by human Atg4B as well as for formation of the intermediates Atg7-MAP1LC3B (ubiquitin-activating enzyme-substrate) and Atg3-MAP1LC3B (ubiquitin carrier protein-substrate).	Glycine	30-33	autophagy related 7	Homo sapiens	144-148
15355958-9	2004	An in vitro assay showed that Gly(120) is essential for carboxyl-terminal cleavage by human Atg4B as well as for formation of the intermediates Atg7-MAP1LC3B (ubiquitin-activating enzyme-substrate) and Atg3-MAP1LC3B (ubiquitin carrier protein-substrate).	Glycine	30-33	microtubule associated protein 1 light chain 3 beta	Homo sapiens	149-157
11886898-2	2002	One interesting finding in Hamy3 is the glycine to glutamine alteration at residue 741, which corresponds to chicken skeletal muscle myosin glycine 699 (G699).	Glycine	40-47	myosin, heavy chain 15	Gallus gallus	133-139
10455185-5	1999	Analysis of the products of pro-ISG15 processing enzyme demonstrates specific cleavage exclusively at the Gly(157)-Gly(158) peptide bond to generate a mature ISG15 carboxyl terminus.	Glycine	115-118	ISG15 ubiquitin like modifier	Homo sapiens	158-163
15355958-9	2004	An in vitro assay showed that Gly(120) is essential for carboxyl-terminal cleavage by human Atg4B as well as for formation of the intermediates Atg7-MAP1LC3B (ubiquitin-activating enzyme-substrate) and Atg3-MAP1LC3B (ubiquitin carrier protein-substrate).	Glycine	30-33	microtubule associated protein 1 light chain 3 beta	Homo sapiens	207-215
15355958-12	2004	These results indicate that the carboxyl terminus of MAP1LC3B is cleaved to expose Gly(120) for further ubiquitylation-like reactions.	Glycine	83-86	microtubule associated protein 1 light chain 3 beta	Homo sapiens	53-61
15479221-4	2004	METHODS: Frequencies of the following variants were assessed in extremely obese children and healthy underweight controls: Gly/Ser in codon 49 and Arg/Gly in codon 389 of the beta(1)-AR, Arg/Gly in codon 16 and Gln/Glu in codon 27 of the beta(2)-AR, Trp/Arg in codon 64 of the beta(3)-AR.	Glycine	151-154	adrenoceptor beta 1	Homo sapiens	175-185
10477183-11	1999	OP-Tc preference for amino acids in the P2 position was (Gly,Lys,Arg) &gt; Phe &gt; Leu &gt; Pro.	Glycine	57-60	opticin	Bos taurus	0-5
11858857-9	2002	This construct proved to be immunogenic and reduce fertility while directing the immune response to the Val(35)-Gly(200) region of ZP2.	Glycine	112-115	zona pellucida glycoprotein 2	Mus musculus	131-134
15479221-4	2004	METHODS: Frequencies of the following variants were assessed in extremely obese children and healthy underweight controls: Gly/Ser in codon 49 and Arg/Gly in codon 389 of the beta(1)-AR, Arg/Gly in codon 16 and Gln/Glu in codon 27 of the beta(2)-AR, Trp/Arg in codon 64 of the beta(3)-AR.	Glycine	151-154	adrenoceptor beta 1	Homo sapiens	175-185
12378270-0	2002	Methylation of the arginine-glycine-rich region in the fragile X mental retardation protein FMRP differentially affects RNA binding.	Glycine	28-35	nuclear FMR1 interacting protein 2	Homo sapiens	92-96
10510728-1	1999	A heterozygous polymorphism changing GGT40 (Gly) to AGT40 (Ser) in the glucagon receptor gene (GCG-R) was reported to be associated with non-insulin-dependent diabetes mellitus (NIDDM).	Glycine	44-47	glucagon receptor	Homo sapiens	71-88
15485923-6	2004	A mutation in a glycine residue in this N-terminal region of POL1 compromises the ability of Pol1p to associate with Spt16p and alters the temporal ordered association of Ctf4p with Pol1p.	Glycine	16-23	DNA-directed DNA polymerase alpha catalytic subunit POL1	Saccharomyces cerevisiae S288C	61-65
10510728-1	1999	A heterozygous polymorphism changing GGT40 (Gly) to AGT40 (Ser) in the glucagon receptor gene (GCG-R) was reported to be associated with non-insulin-dependent diabetes mellitus (NIDDM).	Glycine	44-47	glucagon receptor	Homo sapiens	95-100
10419831-2	1999	In the present example, connective tissue-activating peptide (CTAPIII) and neutrophil-activating peptide 2 (NAP/2) were generated by digestion of a ubiquitin-CTAPIII conjugate with YUH1 and HIV Pr, respectively, as indicated below: [see text] YUH1 cleaved at the peptide bond formed by the C-terminal Gly(76) of ubiquitin (Ub) and the N-terminal Asn(1) of the 85-residue peptide CTAPIII.	Glycine	301-304	pro-platelet basic protein	Homo sapiens	108-113
10419831-2	1999	In the present example, connective tissue-activating peptide (CTAPIII) and neutrophil-activating peptide 2 (NAP/2) were generated by digestion of a ubiquitin-CTAPIII conjugate with YUH1 and HIV Pr, respectively, as indicated below: [see text] YUH1 cleaved at the peptide bond formed by the C-terminal Gly(76) of ubiquitin (Ub) and the N-terminal Asn(1) of the 85-residue peptide CTAPIII.	Glycine	301-304	pro-platelet basic protein	Homo sapiens	158-165
11860506-7	2002	The study shows that desensitization and resensitization kinetics of homomeric GluR2 flop channels are controlled by a single amino acid exchange (glycine by arginine) at the R/G site.	Glycine	147-154	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	79-84
15485923-6	2004	A mutation in a glycine residue in this N-terminal region of POL1 compromises the ability of Pol1p to associate with Spt16p and alters the temporal ordered association of Ctf4p with Pol1p.	Glycine	16-23	DNA-directed DNA polymerase alpha catalytic subunit POL1	Saccharomyces cerevisiae S288C	93-98
10419831-2	1999	In the present example, connective tissue-activating peptide (CTAPIII) and neutrophil-activating peptide 2 (NAP/2) were generated by digestion of a ubiquitin-CTAPIII conjugate with YUH1 and HIV Pr, respectively, as indicated below: [see text] YUH1 cleaved at the peptide bond formed by the C-terminal Gly(76) of ubiquitin (Ub) and the N-terminal Asn(1) of the 85-residue peptide CTAPIII.	Glycine	301-304	pro-platelet basic protein	Homo sapiens	158-165
15485923-6	2004	A mutation in a glycine residue in this N-terminal region of POL1 compromises the ability of Pol1p to associate with Spt16p and alters the temporal ordered association of Ctf4p with Pol1p.	Glycine	16-23	chromatin-remodeling protein SPT16	Saccharomyces cerevisiae S288C	117-123
11751969-8	2002	Affinity-enhancing substitutions frequently involved replacement of a negative charge, or Gly or Pro, hallmark amino acids of CII structure.	Glycine	90-93	serpin family D member 1	Homo sapiens	126-129
15485923-6	2004	A mutation in a glycine residue in this N-terminal region of POL1 compromises the ability of Pol1p to associate with Spt16p and alters the temporal ordered association of Ctf4p with Pol1p.	Glycine	16-23	chromatin-binding protein CTF4	Saccharomyces cerevisiae S288C	171-176
11713266-3	2001	SMN binds preferentially and directly to the symmetrical dimethylarginine (sDMA)-modified arginine- and glycine-rich (RG-rich) domains of SmD1 and SmD3.	Glycine	104-111	small nuclear ribonucleoprotein D3 polypeptide	Homo sapiens	147-151
15485923-6	2004	A mutation in a glycine residue in this N-terminal region of POL1 compromises the ability of Pol1p to associate with Spt16p and alters the temporal ordered association of Ctf4p with Pol1p.	Glycine	16-23	DNA-directed DNA polymerase alpha catalytic subunit POL1	Saccharomyces cerevisiae S288C	182-187
15542918-3	2004	The amino terminus of the mature Bin1b peptide contains a conserved myristoylated Gly residue.	Glycine	82-85	sperm associated antigen 11A	Rattus norvegicus	33-38
11723250-7	2001	ALX 5407 completely inhibited glycine transport in the GlyT1 cells, with an IC(50) value of 3 nM, but had little or no activity at the human GlyT2 transporter, at other binding sites for glycine, or at other neurotransmitter transporters.	Glycine	30-37	hematopoietic SH2 domain containing	Homo sapiens	0-3
11801295-1	2001	Glutamate (GLU) associated with glycine, act as co-transmitter at the N-methyl-D-aspartate/glycine-B (NMDA/GLY(B)) receptor.	Glycine	32-39	Glycine auxotroph B, complementation of hamster	Homo sapiens	102-113
10375657-7	1999	On the other hand, the rCBF response abolished by 1000 microg/kg of (+)-3-amino-1-hydroxy-2-pyrrolidone (HA-966), an antagonist of the glycine modulatory site on the N-methyl-d-aspartate (NMDA) receptors, was not restored by FK960 (1000 microg/kg, i.v.).	Glycine	135-142	CCAAT/enhancer binding protein zeta	Rattus norvegicus	23-27
15542918-4	2004	We studied the requirement of the terminal myristoylated Gly residue in the bactericidal activity of Bin1b and found that the terminal myristoylated Gly residue is not essential for the bactericidal activity.	Glycine	57-60	sperm associated antigen 11A	Rattus norvegicus	101-106
11572853-9	2001	NR1(F639A) did not alter the agonist potency of glutamate but did produce a leftward shift in the glycine concentration response for receptors containing NR2A and NR2B subunits.	Glycine	98-105	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	163-167
15199058-7	2004	Mutation to the rodent homologue glycine or glutamate resulted in a significant reduction in binding compared with native IgE, whereas conservative substitution with arginine effected a small, but statistically significant, enhancement of CD23 binding.	Glycine	33-40	Fc epsilon receptor II	Homo sapiens	239-243
15265500-1	2004	A series of benzoylpiperidine analogs related to 4a was prepared, and their ability to inhibit the uptake of [(14)C]-glycine in COS7 cells transfected with human glycine transporter type-2 (GlyT-2) was evaluated.	Glycine	117-124	solute carrier family 6 member 5	Homo sapiens	162-188
11703582-1	2001	BACKGROUND: Although apolipoprotein A-II (apoA-II) associated amyloidosis has been described in the senescent accelerated mouse (SAM) model of aging, so far there has been no report of human apoA-II amyloidosis except for a recent report of renal amyloidosis resulting from a stop-codon to glycine mutation of apoA-II.	Glycine	290-297	apolipoprotein A-II	Mus musculus	21-40
11703582-1	2001	BACKGROUND: Although apolipoprotein A-II (apoA-II) associated amyloidosis has been described in the senescent accelerated mouse (SAM) model of aging, so far there has been no report of human apoA-II amyloidosis except for a recent report of renal amyloidosis resulting from a stop-codon to glycine mutation of apoA-II.	Glycine	290-297	apolipoprotein A-II	Mus musculus	42-49
11486036-5	2001	YY1 was acetylated in two regions: both p300 and PCAF acetylated the central glycine-lysine-rich domain of residues 170 to 200, and PCAF also acetylated YY1 at the C-terminal DNA-binding zinc finger domain.	Glycine	77-84	E1A binding protein p300	Homo sapiens	40-44
11486036-5	2001	YY1 was acetylated in two regions: both p300 and PCAF acetylated the central glycine-lysine-rich domain of residues 170 to 200, and PCAF also acetylated YY1 at the C-terminal DNA-binding zinc finger domain.	Glycine	77-84	lysine acetyltransferase 2B	Homo sapiens	49-53
11486036-5	2001	YY1 was acetylated in two regions: both p300 and PCAF acetylated the central glycine-lysine-rich domain of residues 170 to 200, and PCAF also acetylated YY1 at the C-terminal DNA-binding zinc finger domain.	Glycine	77-84	lysine acetyltransferase 2B	Homo sapiens	132-136
10359652-0	1999	Expression and characterization of a glycine-binding fragment of the N-methyl-D-aspartate receptor subunit NR1.	Glycine	37-44	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	69-110
10359652-3	1999	It has been proposed that the NR1 subunit possesses a glycine-binding site.	Glycine	54-61	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	30-33
10194517-2	1999	Occupation of these receptors, via Arg-Gly-Asp (RGD) recognition sequences, leads to activation of focal adhesion kinase (FAK).	Glycine	39-42	protein tyrosine kinase 2	Homo sapiens	99-120
10194517-2	1999	Occupation of these receptors, via Arg-Gly-Asp (RGD) recognition sequences, leads to activation of focal adhesion kinase (FAK).	Glycine	39-42	protein tyrosine kinase 2	Homo sapiens	122-125
15223302-6	2004	On the basis of secondary structure predictions, it was hypothesized that the amino acid motifs Pro-Ile-Gly of mUcnII and Pro-Thr-Asn of mUcnIII decrease alpha-helicity and thereby impair binding to CRF1.	Glycine	104-107	corticotropin releasing hormone receptor 1	Homo sapiens	199-203
10077621-7	1999	An early onset colorectal tumor is heterozygous for the analogous Gly --&gt; Ser mutation in hMSH2, and a second hMSH2 mutation was not found, suggesting that this missense mutation may predispose to cancer via a dominant mutator effect.	Glycine	66-69	mutS homolog 2	Homo sapiens	93-98
10208572-3	1999	Since [3H]L-689,560, [3H]CGP 39653 and [3H]ifenprodil label the glycine, glutamate and ifenprodil sites of the NMDA receptor complex, which are associated with NR1, NR1/NR2A and NR1/NR2B subunits respectively, our findings suggest that NR2B-containing receptors are selectively up-regulated in superior temporal cortex in schizophrenia.	Glycine	64-71	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	182-186
10208572-3	1999	Since [3H]L-689,560, [3H]CGP 39653 and [3H]ifenprodil label the glycine, glutamate and ifenprodil sites of the NMDA receptor complex, which are associated with NR1, NR1/NR2A and NR1/NR2B subunits respectively, our findings suggest that NR2B-containing receptors are selectively up-regulated in superior temporal cortex in schizophrenia.	Glycine	64-71	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	236-240
11493674-3	2001	One of these, designated type II GnRH (GnRH II: pGlu-His-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2), is conserved from fish to man and is widely distributed in the brain, suggesting important neuromodulatory functions such as regulating K+ channels and stimulating sexual arousal.	Glycine	65-68	gonadotropin releasing hormone 2	Homo sapiens	39-46
11457520-0	2001	Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22.	Glycine	77-84	proprotein convertase subtilisin/kexin type 5	Homo sapiens	31-34
11418470-11	2001	RGDS (Arg-Gly-Asp-Ser) or antibodies to alpha5beta1 or alphaIIbbeta3 integrins caused a partial decrease in LPA-induced deposition of FITC-FN.	Glycine	10-13	ral guanine nucleotide dissociation stimulator	Homo sapiens	0-4
11336637-2	2001	Human MDR1 variants with mutations affecting a conserved glycine residue within the ABC signature of either or both ABC units (G534D, G534V, G1179D and G534D/G1179D) were expressed and characterized in Spodoptera frugiperda (Sf9) cell membranes.	Glycine	57-64	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	84-87
11336637-2	2001	Human MDR1 variants with mutations affecting a conserved glycine residue within the ABC signature of either or both ABC units (G534D, G534V, G1179D and G534D/G1179D) were expressed and characterized in Spodoptera frugiperda (Sf9) cell membranes.	Glycine	57-64	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	116-119
11336637-6	2001	On the basis of these results and recent structural information on an ABC-ABC dimer [Hopfner, Karcher, Shin, Craig, Arthur, Carney and Tainer (2000) Cell 101, 789-800], we propose a key role of these glycine residues in the interdomain communication regulating drug-induced ATP hydrolysis.	Glycine	200-207	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	70-73
10024091-4	1999	Recently, it was reported that GLP-1 became resistant to DPPIV when the alanine residue at position 8 was replaced by a glycine (GLP-1-Gly8).	Glycine	120-127	glucagon like peptide 1 receptor	Homo sapiens	31-36
15312765-6	2004	Based on hydrogen-deuterium exchange experiments, glycine substitution reduces flexibility in several polypeptide regions in Csk, tyrosine substitution increases flexibility, and alanine substitution leads to mixed effects compared to wild-type.	Glycine	50-57	C-terminal Src kinase	Homo sapiens	125-128
11336637-6	2001	On the basis of these results and recent structural information on an ABC-ABC dimer [Hopfner, Karcher, Shin, Craig, Arthur, Carney and Tainer (2000) Cell 101, 789-800], we propose a key role of these glycine residues in the interdomain communication regulating drug-induced ATP hydrolysis.	Glycine	200-207	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	74-77
15200428-8	2004	In SHR cells [(14)C]-L-DOPA uptake was 25% through system B(0), 25% through LAT2 (resulting from inhibition by 1 mmol/L glycine, L-alanine, L-serine, and L-threonine), and the remaining 50% through LAT1.	Glycine	120-127	linker for activation of T cells family, member 2	Rattus norvegicus	76-80
11157057-2	2001	Substitution of lysine (K) or glycine (G) for arginine (R) at HIV-1 gag residue 264 (R264K and R264G) results in epitopes that bind to HLA-B27 poorly.	Glycine	30-37	Pr55(Gag)	Human immunodeficiency virus 1	68-71
11450847-0	2001	Chromosomal localization, structure, single-nucleotide polymorphisms, and expression of the human H-protein gene of the glycine cleavage system (GCSH), a candidate gene for nonketotic hyperglycinemia.	Glycine	120-127	glycine cleavage system protein H	Homo sapiens	145-149
10330579-2	1999	A model of spatial structure of the synthetic peptide rp142 (24 amino acid residues) containing the immunodominant epitope of the HIV-1 protein gp120 in the region Gly-10-Phe-15 was constructed by the method of "constrained" molecular mechanics, which uses the algorithms of theoretical conformational analysis, based on NMR spectroscopy data.	Glycine	164-167	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	144-149
15155838-3	2004	Glutamate-61 is located in the conserved transmembrane domain I of GAT-4, whereas in the related taurine-transporter taurine transporter (TAUT), glycine occupies the equivalent position.	Glycine	145-152	solute carrier family 6 member 6	Homo sapiens	138-142
10071784-0	1999	Reactive affinity probes for the mapping of the glycine-binding site of the NMDA receptor NR1 subunit.	Glycine	48-55	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	90-93
10071784-4	1999	These compounds compete with 3H-DCKA binding to rat brain membranes at equilibrium with nanomolar to low-micromolar affinities, and antagonize glycine-evoked currents in oocytes transfected with wild-type NR1-NR2B.	Glycine	143-150	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	205-208
11141191-7	2001	We also discovered a "hidden homology" in the TIM barrel, an invariant Gly located upstream in the sequence before the conserved Asp in beta-strand 3.	Glycine	71-74	Rho guanine nucleotide exchange factor 5	Homo sapiens	46-49
14993215-3	2004	Analysis of the SP-A/SP-D chimeras, in which progressively longer carboxyl-terminal regions of SP-A were replaced with the corresponding SP-D regions, has revealed that the SP-D region Gly(346)-Phe(355) can be substituted for the SP-A region Leu(219)-Phe(228) without altering the SP-A activity of enhancing the phagocytosis and that the SP-A region Cys(204)-Cys(218) is required for the SP-A-mediated phagocytosis.	Glycine	185-188	surfactant associated protein A1	Mus musculus	16-20
11069235-4	2000	Tat proteins with inactivating substitutions in the arginine-glycine-aspartic acid or basic domain were still active in inducing PMNL migration, whereas Tat peptides mapped the migration and Ca(2+) mobilization activity to a cysteine-rich core domain, previously described as a Tat "chemokine-like" region (peptide CysL(24-51)).	Glycine	61-68	tyrosine aminotransferase	Homo sapiens	0-3
11099414-2	2000	The pro-apoptotic protein BID underwent posttranslational (rather than classic cotranslational) N-myristoylation when cleavage by caspase 8 caused exposure of a glycine residue.	Glycine	161-168	caspase 8	Homo sapiens	130-139
10461108-3	1999	MDCK cells (2 x 10(6) cells/well) were cultured to a confluent state, and the binding of OPN to the cellular surface was then inhibited by adding one of the following 4 substances: human OPN polyclonal antibody, thrombin, cyclic Arg-Gly-Asp (RGD) peptides and tunicamycin.	Glycine	233-236	secreted phosphoprotein 1	Canis lupus familiaris	89-92
9841880-2	1998	To identify cysteine residues in GLCL that are involved in its activity, eight conserved cysteine residues in human GLCL catalytic subunit (hGLCLC) were replaced with glycine residues by PCR-based site-directed mutagenesis.	Glycine	167-174	glutamate-cysteine ligase catalytic subunit	Homo sapiens	33-37
15144526-7	2004	RESULTS: B19 in a 0.3 M glycine solution was reduced to 1:10(7.5) (7.5-log) by nanofiltration with a 35-nm pore-sized filter, whereas in PBS it was not reduced.	Glycine	24-31	eva-1 homolog C	Homo sapiens	9-12
9834112-8	1998	Both the phagocytosis and production of the cytokines were suppressed by either phospho-L-serine or RGDS (Arg-Gly-Asp-Ser), but not by RGES (Arg-Gly-Glu-Ser).	Glycine	110-113	ral guanine nucleotide dissociation stimulator	Homo sapiens	100-104
10978331-2	2000	The transduction of a human placental cDNA retroviral library into glyB cells, a Chinese hamster ovary K1 subline that is deficient in the transport of folates into mitochondria, resulted in the complementation of glycine auxotrophy of these cells.	Glycine	214-221	Glycine auxotroph B, complementation of hamster	Homo sapiens	67-71
10978331-5	2000	The subcloned cDNA complemented the glycine auxotrophy of glyB cells and reinstated folate accumulation in the mitochondria of transfected cells.	Glycine	36-43	Glycine auxotroph B, complementation of hamster	Homo sapiens	58-62
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase 12	Homo sapiens	157-162
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase 12	Homo sapiens	163-172
9805126-0	1998	Heterozygous glycine substitution in the COL11A2 gene in the original patient with the Weissenbacher-Zweymuller syndrome demonstrates its identity with heterozygous OSMED (nonocular Stickler syndrome).	Glycine	13-20	collagen type XI alpha 2 chain	Homo sapiens	41-48
9805126-2	1998	No mutations were found in the COL2A1 gene but the COL11A2 gene contained a single-base mutation that converted a codon for an obligate glycine to a codon for glutamate at position alpha 2-955 (G955E).	Glycine	136-143	collagen type XI alpha 2 chain	Homo sapiens	51-58
9722148-0	1998	The human immunodeficiency virus-1 envelope protein gp120 binds through its V3 sequence to the glycine site of N-methyl-D-aspartate receptors mediating noradrenaline release in the hippocampus.	Glycine	95-102	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	52-57
9788244-4	1998	Taurine- and glycine-conjugated bile salts (anionic steroid detergent-like molecules), at concentrations well below their critical micellar concentrations, stimulated PC transfer activity of SCP2 80- to 140-fold.	Glycine	13-20	sterol carrier protein 2	Homo sapiens	191-195
9777022-2	1998	The fractional extraction of postprandial carboxyamidated and glycine-extended gastrin in the kidneys was 0.21 +/- 0.01 and 0.16 +/- 0.02, but the respective urinary clearance comprised only 0.57 +/- 0.03 and 0.44 +/- 0.05% of the GFR (P &lt; 0.02).	Glycine	62-69	gastrin	Sus scrofa	79-86
9777022-3	1998	The respective total body clearance of carboxyamidated and glycine-extended gastrin-17 (gastrin-17 and gastrin-17Gly) during continuous infusion was 22.9 +/- 1.5 and 19.6 +/- 1.4 mL kg-1 min-1 (NS), and the renal fractional extraction of the peptides was 0.31 +/- 0.03 and 0.29 +/- 0.05, respectively.	Glycine	59-66	gastrin	Sus scrofa	76-83
9683473-9	1998	The glycine 85 codon in trfA mRNA is GGU, and a change of this to GGC did not significantly affect expression.	Glycine	4-11	TrfA-like protein	Escherichia coli	24-28
9668083-7	1998	In vitro binding assays show that the glycine-arginine rich domain of nucleolin (RGG domain) is sufficient for the interaction with one of these proteins.	Glycine	38-45	nucleolin	Rattus norvegicus	70-79
9654451-6	1998	In addition, the position of the two C-terminal Gly residues required for isopeptide bond formation is conserved between ubiquitin and SUMO-1.	Glycine	48-51	small ubiquitin like modifier 1	Homo sapiens	135-141
9624176-6	1998	A glycine residue (Gly711) adjacent to the Y712SPL motif is also important for binding to mu 2/AP-2 and internalization.	Glycine	2-9	adaptor related protein complex 1 subunit mu 2	Homo sapiens	90-94
9620970-5	1998	These similarities and the presence of flavin adenine dinucleotide- or NAD(P)-binding motifs in HcnB and HcnC suggest that HCN synthase may act as a dehydrogenase in the reaction leading from glycine to HCN and CO2.	Glycine	192-199	DUF3108 domain-containing protein	Pseudomonas protegens CHA0	149-162
9593857-7	1998	These experiments indicate that blocking the NMDA receptor-channel (and to a lesser extent the glycine site) or stimulating alpha2-adrenoceptors, profoundly increases AADC activity, more especially in the SN than CS.	Glycine	95-102	dopa decarboxylase	Rattus norvegicus	167-171
9556603-8	1998	[3H]CGP 61594 is a promising tool to identify the NR2 subunit domains that contribute to differential glycine antagonist sites of NMDA receptor subtypes.	Glycine	102-109	nodal homolog 2 L homeolog	Xenopus laevis	50-53
9497328-5	1998	In these mimics we found 1) that both conformation and protein binding properties are altered by insertion of Gly spacers C-terminal to the heptad repeat sequences; 2) that the cytoskeletal proteins talin and filamin are among the polypeptides that bind to the integrin beta1A tail.	Glycine	110-113	filamin C	Homo sapiens	209-216
9579221-12	1998	There were two base mutations; cysteine 21-->arginine and serine 247-->glycine in the sequences coding for the first extramembranous N-terminal domain and the third extramembranous loop of the ACTH receptor.	Glycine	71-78	melanocortin 2 receptor	Homo sapiens	193-206
9491993-1	1998	In studying chimeras of NR2A and NR2C subunits of the NMDA receptor, we have found that glycine-independent desensitization depends on two regions of the extracellular N-terminal domain.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	33-37
9443839-4	1998	In contrast, microinjection of the ANG II type 1 receptor (AT1) antagonist CV 11974 into the RVLM reduced MAP and HR, accompanied by increased release of GLY, TAU and GABA.	Glycine	154-157	angiotensin II receptor, type 1a	Rattus norvegicus	35-57
9443839-4	1998	In contrast, microinjection of the ANG II type 1 receptor (AT1) antagonist CV 11974 into the RVLM reduced MAP and HR, accompanied by increased release of GLY, TAU and GABA.	Glycine	154-157	angiotensin II receptor, type 1a	Rattus norvegicus	59-62
9398229-2	1997	When these Trp residues are replaced with Gly in either recombinant fragments or synthetic peptides of CaD, the affinity for CaM is decreased by at least 10-fold, suggesting that both of these residues are important for the interaction of CaD with CaM.	Glycine	42-45	caldesmon 1	Gallus gallus	103-106
9398229-2	1997	When these Trp residues are replaced with Gly in either recombinant fragments or synthetic peptides of CaD, the affinity for CaM is decreased by at least 10-fold, suggesting that both of these residues are important for the interaction of CaD with CaM.	Glycine	42-45	caldesmon 1	Gallus gallus	239-242
9375665-4	1997	Brief application of an NMDA/glycine solution to cells markedly increased intracellular calcium in cells transfected with NR1/NR2A, NR1/NR2B, or NR1/NR2A/NR2B as measured by fura-2 calcium imaging.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	136-140
9342184-1	1997	Osteopontin (OPN) is a secreted phosphoprotein that binds to cells via an Arg-Gly-Asp sequence and to mineralized surfaces.	Glycine	78-81	secreted phosphoprotein 1	Mus musculus	0-11
9342184-1	1997	Osteopontin (OPN) is a secreted phosphoprotein that binds to cells via an Arg-Gly-Asp sequence and to mineralized surfaces.	Glycine	78-81	secreted phosphoprotein 1	Mus musculus	13-16
9311856-10	1997	Moreover, when glycine residues were engineered at the positions where serine and threonine changes evolve in V1 of SIVMneCL8, there was no change in antigenicity compared to SIVMneCL8.	Glycine	15-22	immunoglobulin kappa variable 1-5	Homo sapiens	110-112
9307967-1	1997	Glutathione (GSH) synthetase (Gsh2) catalyzes the ATP-dependent synthesis of GSH from gamma-glutamylcysteine (gamma-Glu-Cys) and glycine.	Glycine	129-136	glutathione synthase	Saccharomyces cerevisiae S288C	30-34
9234729-3	1997	The polypeptide of galectin-3 has two domains, a carboxyl-terminal CRD fused onto a proline- and glycine-rich amino-terminal domain.	Glycine	97-104	galectin 3	Homo sapiens	19-29
9162015-7	1997	When the conserved Gly-Gly residues of sentrin were changed to Gly-Ala, only sentrin monomer and p90 but not the high molecular mass bands were observed.	Glycine	19-22	small ubiquitin like modifier 1	Homo sapiens	39-46
9162015-7	1997	When the conserved Gly-Gly residues of sentrin were changed to Gly-Ala, only sentrin monomer and p90 but not the high molecular mass bands were observed.	Glycine	19-22	small ubiquitin like modifier 1	Homo sapiens	77-84
9162015-7	1997	When the conserved Gly-Gly residues of sentrin were changed to Gly-Ala, only sentrin monomer and p90 but not the high molecular mass bands were observed.	Glycine	23-26	small ubiquitin like modifier 1	Homo sapiens	39-46
9179843-6	1997	In addition, a mutant LTB with a single Gly-33--&gt;Asp substitution that completely lacked affinity for both GM1 and non-GM1 glycosphingolipids could still bind to receptors in the intestinal cell membranes and to polyglycosylceramides.	Glycine	40-43	lymphotoxin-beta	Oryctolagus cuniculus	22-25
9144769-1	1997	Fast synaptic neurotransmission is mediated by ligand-gated ion-channel (LGIC) receptors, which include receptors for acetylcholine, serotonin, GABA, glycine, and glutamate.	Glycine	150-157	glycine receptor alpha 3	Homo sapiens	47-71
9144769-1	1997	Fast synaptic neurotransmission is mediated by ligand-gated ion-channel (LGIC) receptors, which include receptors for acetylcholine, serotonin, GABA, glycine, and glutamate.	Glycine	150-157	glycine receptor alpha 3	Homo sapiens	73-77
10191718-1	1997	We have used the method of disequilibrium pattern analysis to examine associations between the threonine-glycine (Thr-Gly) encoding repeat region of the clock gene period (per) of Drosophila melanogaster, and polymorphic sites both upstream and downstream of the repeat, in a number of European fly populations.	Glycine	105-112	Clock	Drosophila melanogaster	153-158
10191718-1	1997	We have used the method of disequilibrium pattern analysis to examine associations between the threonine-glycine (Thr-Gly) encoding repeat region of the clock gene period (per) of Drosophila melanogaster, and polymorphic sites both upstream and downstream of the repeat, in a number of European fly populations.	Glycine	118-121	Clock	Drosophila melanogaster	153-158
9032343-2	1997	Elucidation of the biochemical role of CyPA would be aided by a detailed analysis of the genetic requirements for the formation of the Gag-CyPA complex; previous experiments have demonstrated the requirement for a critical proline and the immediately preceding glycine, located within the capsid domain of Gag, but nothing is known about the necessary CyPA residues.	Glycine	261-268	Pr55(Gag)	Human immunodeficiency virus 1	135-138
9038211-2	1997	We introduced one of these mutations, Asp-556 --&gt; Gly, into the rat LH/hCG receptor and demonstrated that the mutant receptor constitutively activated adenylate cyclase in transfected 293 T cells.	Glycine	53-56	chorionic gonadotropin subunit beta 5	Homo sapiens	74-77
9324163-6	1997	The CCK-B receptor antagonist L365,260 almost totally blocked MAPK activation in AR42J cells after stimulation with gastrin and glycine-extended gastrin and substantially reduced the activation of both kinases by CCK-8, while the CCK-A receptor antagonist L364,718 was much less effective.	Glycine	128-135	mitogen activated protein kinase 3	Rattus norvegicus	62-66
9324163-6	1997	The CCK-B receptor antagonist L365,260 almost totally blocked MAPK activation in AR42J cells after stimulation with gastrin and glycine-extended gastrin and substantially reduced the activation of both kinases by CCK-8, while the CCK-A receptor antagonist L364,718 was much less effective.	Glycine	128-135	cholecystokinin A receptor	Rattus norvegicus	230-244
9101295-3	1997	DNA sequence analysis of delta-globin gene identified two "novel" mutations in the coding regions of the gene; the cd11 (GTC-->GGC) resulting in the substitution of valine for glycine (:HbA2-Pylos) and the cd85(TTT-->TCT) resulting in the substitution of phenylalanine for serine (:HbA2-Etolia).	Glycine	176-183	hemoglobin subunit alpha 2	Homo sapiens	186-190
8940197-2	1996	Functionally active scIL5 was constructed using recombinant DNA methods by linking two IL5 monomers with a Gly-Gly linker.	Glycine	107-110	interleukin 5	Homo sapiens	22-25
8940197-2	1996	Functionally active scIL5 was constructed using recombinant DNA methods by linking two IL5 monomers with a Gly-Gly linker.	Glycine	111-114	interleukin 5	Homo sapiens	22-25
8938178-1	1996	We identified kan-1 complementary DNA (cDNA), the sequence of which is identical to bile acid CoA:amino acid N-acyltransferase (BAT), a liver enzyme that catalyzes the conjugation of bile acids with glycine or taurine.	Glycine	199-206	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	84-126
8938178-1	1996	We identified kan-1 complementary DNA (cDNA), the sequence of which is identical to bile acid CoA:amino acid N-acyltransferase (BAT), a liver enzyme that catalyzes the conjugation of bile acids with glycine or taurine.	Glycine	199-206	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	128-131
9247881-5	1996	The NMDA receptor response is not only inhibited but also potentiated by Mg2+, and the latter action is due to an interaction of a Mg2+ site with either glycine- or proton-binding site.	Glycine	153-160	mucin 7, secreted	Homo sapiens	73-76
9247881-5	1996	The NMDA receptor response is not only inhibited but also potentiated by Mg2+, and the latter action is due to an interaction of a Mg2+ site with either glycine- or proton-binding site.	Glycine	153-160	mucin 7, secreted	Homo sapiens	131-134
8937481-0	1996	Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids.	Glycine	61-68	acyl-CoA synthetase medium chain family member 1	Homo sapiens	16-48
8955518-17	1996	We therefore suggest that the glycine site plays a lesser role in modulating NMDA receptor function in the cerebellum and may explain why cells expressing NMDA receptors composed of NR1/NR2C subunits are particularly resistant to excitatory amino acid-induced neurotoxicity.	Glycine	30-37	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	182-185
8959022-5	1996	The cloning and sequencing of a cDNA encoding ssCRE-BP showed that the protein possesses a glycine-rich domain and a glutamine-rich domain in the amino terminus and the carboxyl terminus, respectively.	Glycine	91-98	purine rich element binding protein A	Mus musculus	46-54
8859015-2	1996	In whole-cell electrophysiological recordings, application of NMDA/glycine elicited inward currents at negative holding potentials in human NMDAR1A/2A (hNMDAR1A/2A)- and hNMDAR1A/2B-expressing cells.	Glycine	67-74	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	170-181
8902847-5	1996	These replacements included beta 22Gly, beta 24Pro and beta 25Val with Glu, Arg and Phe in beta 1, 45Leu Gln Gly Val Leu Pro Ala Leu Pro53 with Tyr Lys Asn Pro Ala Arg Pro Leu Ile in beta 2 and 73Pro Arg Gly with Ala His His in the beta 3 loop.	Glycine	109-112	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	28-34
8794904-6	1996	Conversely, heteromeric NR1/NR2B receptors were more sensitive to activation by glycine than were NR1/NR2A receptors.	Glycine	80-87	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	24-27
8718865-6	1996	The ability of bleomycin hydrolase to oligomerize was neither affected by the subtle cysteine/serine mutation nor affected by cysteine/arginine or histidine/glycine mutations.	Glycine	157-164	bleomycin hydrolase	Saccharomyces cerevisiae S288C	15-34
8702554-9	1996	Analysis using the PredictProtein program suggests a common structure among the microbial and eukaryotic N-acetyltransferases in the region corresponding to the RGFGIGS of human SSAT consisting of an alpha-helix usually preceded by a glycine loop.	Glycine	234-241	spermidine/spermine N1-acetyltransferase 1	Homo sapiens	178-182
8702554-10	1996	Our data are consistent with the hypothesis that Arg-101 and the proximal glycine loop are necessary for the activity of human SSAT.	Glycine	74-81	spermidine/spermine N1-acetyltransferase 1	Homo sapiens	127-131
8824571-5	1996	Amino acid usage in the CDR3 region is nonrandom with a predominance of charged or polar residues in the TCRA transcript and a majority of glycines in TCRB.	Glycine	139-147	CDR3	Homo sapiens	24-28
8605964-14	1996	Further, the omission of Epo caused an 80% decrease in the number of BFU-E and a corresponding 94% decrease in the number of CD71++gly A- cells, thereby maintaining the relationship between CD71++gly A- cells and BFU-E.	Glycine	131-134	transferrin receptor	Homo sapiens	125-129
8598221-1	1996	The hematopoietic cell recognition sites of human fibronectin (FN) are the Arg-Gly-Asp-Ser (RGDS) sequence recognized by widely distributed integrin receptor alpha 5 beta 1 and the type III connecting segment (III CS) containing two cell-binding sites, designated CS1 and CS5, that are recognized by the alpha 4 beta 1 receptor.	Glycine	79-82	ral guanine nucleotide dissociation stimulator	Homo sapiens	92-96
11101139-7	2000	Three elastases, molecular masses of 27, 29, 31 kDa, might be elastase isozymes that have the same NH2-terminal amino acid sequences of Ile-Val-Gly-Gly-Arg-Arg-Ala.	Glycine	144-147	elastase, neutrophil expressed	Homo sapiens	6-14
11101139-7	2000	Three elastases, molecular masses of 27, 29, 31 kDa, might be elastase isozymes that have the same NH2-terminal amino acid sequences of Ile-Val-Gly-Gly-Arg-Arg-Ala.	Glycine	148-151	elastase, neutrophil expressed	Homo sapiens	6-14
10976799-7	2000	MMP-2 (Mr 72 000 type IV collagenase; gelatinase A) was found to cleave the substrates at two sites, a Gly-Ile bond and a Gly-Gln bond.	Glycine	103-106	matrix metallopeptidase 2	Homo sapiens	0-5
10976799-7	2000	MMP-2 (Mr 72 000 type IV collagenase; gelatinase A) was found to cleave the substrates at two sites, a Gly-Ile bond and a Gly-Gln bond.	Glycine	122-125	matrix metallopeptidase 2	Homo sapiens	0-5
10976799-10	2000	Further design variations for these substrates need to consider the presence of more stable triple-helical conformation (to eliminate MMP-3 binding) and the removal of Gly-Gln bonds that may be susceptible to MMP-2.	Glycine	168-171	matrix metallopeptidase 2	Homo sapiens	209-214
10825173-3	2000	The tropoelastin-binding site was localized to a region beginning at the glycine-rich and proline-rich regions of fibrillin-2 and fibrillin-1, respectively, and continuing through the second 8-cysteine domain.	Glycine	73-80	fibrillin 2	Homo sapiens	114-125
10930424-1	2000	Limited proteolysis of DsbC with trypsin resulted in a compact and stable C-terminal fragment (residues 66-216), fDsbC, which retains the active site sequence, -Cys(98)-Gly-Tyr-Cys(101)-, and shows only minor differences in conformation compared with that of the intact molecule.	Glycine	169-172	putative protein DsbC	Escherichia coli	23-27
10813812-2	2000	The trans-substituted histidine to glycine mutant of sperm whale myoglobin (H93G Mb) is used to study energetics of proximal hydrogen bonding, proximal ligand-heme interactions, and coupling to distal ligand binding.	Glycine	35-42	myoglobin	Physeter catodon	65-74
10831834-11	2000	For example, a glycine/proline-rich domain in the central variable region functions to recruit the histone deacetylase Rpd3 to the template.	Glycine	15-22	histone deacetylase 3	Homo sapiens	119-123
10775416-5	2000	A met7 gly1 strain is auxotrophic for glycine when grown on glucose but prototrophic when grown on glycerol.	Glycine	38-45	tetrahydrofolate synthase	Saccharomyces cerevisiae S288C	2-6
10737855-6	2000	01) smaller implant-side cranial dimensions and mandibular condyles, all glycine rats showed increased gracility of implant-side bones, and deviation of their facial skeleton away from the implant-side; this was in contrast to the generally larger implant-side bony structures in both glutamate and TRH rats.	Glycine	73-80	thyrotropin releasing hormone	Rattus norvegicus	299-302
10734121-11	2000	Asc-1 preferred small neutral amino acids such as Gly, L-Ala, L-Ser, L-Thr, and L-Cys, and alpha-aminoisobutyric acid as substrates.	Glycine	50-53	anterior suture cataract 1	Mus musculus	0-5
10753500-5	2000	Sequencing studies showed that Balb/c Ifngr encodes a Gly(69) whereas C57BL/6 Ifngr encodes Glu(69) due to a difference at nucleotide 284.	Glycine	54-57	interferon gamma receptor 1	Mus musculus	38-43
10702419-4	2000	The SLPI mutant with Gly(72) (replacing Leu(72) ) lost its ability to block in vivo activation of NF-kappaB, as well as its ability to suppress the lung vascular leak and neutrophil recruitment.	Glycine	21-24	secretory leukocyte peptidase inhibitor	Rattus norvegicus	4-8
10693699-12	2000	The dose of IL-11 producing the overall optimal response based on the parameters measured (galactose absorption, 72% increase over control; glycine absorption, 112% increase over control; and DNA content, 98% increase over control) was 750 microg/kg/d.	Glycine	140-147	interleukin 11	Rattus norvegicus	12-17
10688364-3	2000	For example, at the R/G editing site of gluR-B, -C, and -D RNAs, ADARs change an arginine codon (AGA) to a glycine codon (IGA) so that two protein isoforms can be synthesized from a single encoded mRNA; the highly related gluR-A sequence is not edited at this site.	Glycine	107-114	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	40-46
10786638-2	2000	The derived amino acid sequences of these proteins differ from human HspBP1 in the number of consecutive glycines near the amino-terminus.	Glycine	105-113	HSPA (Hsp70) binding protein 1	Homo sapiens	69-75
10620501-5	2000	To promote the independent folding of the two proteins in the chimaeric toxin, a linear flexible peptide, Gly-Gly-Gly-Gly-Ser, was inserted between the toxin and the ligand to generate restrictocin-linker-anti-TFR(scFv) and anti-TFR(scFv)-linker-restrictocin.	Glycine	106-109	transferrin receptor	Homo sapiens	210-213
10620501-5	2000	To promote the independent folding of the two proteins in the chimaeric toxin, a linear flexible peptide, Gly-Gly-Gly-Gly-Ser, was inserted between the toxin and the ligand to generate restrictocin-linker-anti-TFR(scFv) and anti-TFR(scFv)-linker-restrictocin.	Glycine	106-109	transferrin receptor	Homo sapiens	229-232
10606651-6	2000	Alignment of CstF-64 homologues shows that the proteins have a conserved N-terminal 200 amino acids, the first half of which is the RNA binding domain with the second half likely to contain the CstF-77 interaction domain; a central region variable in length and rich in glycine, proline and glutamine residues and containing an unusual degenerate repeat motif; and then a conserved C-terminal 50 amino acids.	Glycine	270-277	Cleavage stimulation factor 64 kD subunit	Drosophila melanogaster	13-20
10603351-3	2000	The allele snh(st1) is a translocation deleting the bmp7 gene, while snh(ty68) displays a Val-&gt;Gly exhange in a conserved motif of the Bmp7 prodomain.	Glycine	98-101	bone morphogenetic protein 7a	Danio rerio	138-142
10651941-2	2000	This polymorphism encodes a nonconservative Gly --&gt; Arg substitution in amino acid 219 in the extracellular, CD40 binding domain of the molecule.	Glycine	44-47	CD40 molecule	Homo sapiens	112-116
10630424-3	2000	Bovine glycine N-acyltransferase catalyzed conjugation of benzoyl-CoA with Gly (Km(Gly) = 6.2 mM), Asn (Km(Asn) = 129 mM), Gln (Km(Gln) = 353 mM), Ala (Km(Ala) = 1573 mM), Glu (Km(Glu) = 1148 mM) as well as Ser in a sequential mechanism.	Glycine	75-78	glycine N-acyltransferase	Bos taurus	7-32
10630424-3	2000	Bovine glycine N-acyltransferase catalyzed conjugation of benzoyl-CoA with Gly (Km(Gly) = 6.2 mM), Asn (Km(Asn) = 129 mM), Gln (Km(Gln) = 353 mM), Ala (Km(Ala) = 1573 mM), Glu (Km(Glu) = 1148 mM) as well as Ser in a sequential mechanism.	Glycine	83-86	glycine N-acyltransferase	Bos taurus	7-32
10593949-0	1999	Association of two nuclear proteins, Npw38 and NpwBP, via the interaction between the WW domain and a novel proline-rich motif containing glycine and arginine.	Glycine	138-145	WW domain binding protein 11	Homo sapiens	47-52
10654085-3	1999	Radiolabelled amino-acid uptake measurements showed that Agp1p is a general permease for most uncharged amino acids (Ala, Gly, Ser, Thr, Cys, Met, Phe, Tyr, Ile, Leu, Val, Gln and Asn).	Glycine	122-125	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	57-62
10567023-6	1999	h[Gly(2)]GLP-2-treated mice exhibited reduced histological evidence of disease activity, fewer intestinal ulcerations, and decreased myeloperoxidase activity in the small bowel (P &lt; 0.05, h[Gly(2)]GLP-2- vs. saline-treated controls).	Glycine	2-5	glucagon-like peptide 2 receptor	Mus musculus	200-205
10567023-7	1999	h[Gly(2)]GLP-2 significantly reduced cytokine induction, bacteremia, and the percentage of positive splenic and hepatic bacterial cultures (P &lt; 0.05).	Glycine	2-5	glucagon-like peptide 2 receptor	Mus musculus	9-14
10567023-8	1999	h[Gly(2)]GLP-2 enhanced epithelial proliferation (P &lt; 0.05 for increased crypt cell proliferation in h[Gly(2)]GLP-2- vs. saline-treated mice after indomethacin) and reduced apoptosis in the crypt compartment (P &lt; 0.02).	Glycine	2-5	glucagon-like peptide 2 receptor	Mus musculus	9-14
10567023-8	1999	h[Gly(2)]GLP-2 enhanced epithelial proliferation (P &lt; 0.05 for increased crypt cell proliferation in h[Gly(2)]GLP-2- vs. saline-treated mice after indomethacin) and reduced apoptosis in the crypt compartment (P &lt; 0.02).	Glycine	2-5	glucagon-like peptide 2 receptor	Mus musculus	113-118
10567023-8	1999	h[Gly(2)]GLP-2 enhanced epithelial proliferation (P &lt; 0.05 for increased crypt cell proliferation in h[Gly(2)]GLP-2- vs. saline-treated mice after indomethacin) and reduced apoptosis in the crypt compartment (P &lt; 0.02).	Glycine	106-109	glucagon-like peptide 2 receptor	Mus musculus	9-14
10486054-6	1999	On the other hand, when Glu-248, Ala-262, Thr-274, Leu-285, Gly-313, Ala-322, or Val-335 of CvaA protein was mutated, the secretion of ColV was greatly reduced in certain mutants.	Glycine	60-63	Colicin V	Escherichia coli	135-139
10468875-1	1999	The functional defect caused by substitution of Arg527 (--&gt; Trp) and Arg531 (--&gt; Gly, His) in factor VIII (FVIII), was explored by employing FVIII derived from patient plasma and recombinant FVIII variants.	Glycine	87-90	coagulation factor VIII	Homo sapiens	100-111
10468875-1	1999	The functional defect caused by substitution of Arg527 (--&gt; Trp) and Arg531 (--&gt; Gly, His) in factor VIII (FVIII), was explored by employing FVIII derived from patient plasma and recombinant FVIII variants.	Glycine	87-90	coagulation factor VIII	Homo sapiens	113-118
10388568-2	1999	Ubc transfers the ubiquitin (Ub) molecules to target proteins by forming a thioester bond between their active site cysteine residue and the C-terminal glycine residue of ubiquitin.	Glycine	152-159	ubiquitin C	Homo sapiens	0-3
10388657-1	1999	We examined the effect of amino acid substitutions of the GPGR (glycine-proline-glycine-arginine) tip sequence at the V3 domain of the Env protein of human immunodeficiency virus type 1 (HIV-1) on its cell tropism and coreceptor use.	Glycine	64-71	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	135-138
10419831-2	1999	In the present example, connective tissue-activating peptide (CTAPIII) and neutrophil-activating peptide 2 (NAP/2) were generated by digestion of a ubiquitin-CTAPIII conjugate with YUH1 and HIV Pr, respectively, as indicated below: [see text] YUH1 cleaved at the peptide bond formed by the C-terminal Gly(76) of ubiquitin (Ub) and the N-terminal Asn(1) of the 85-residue peptide CTAPIII.	Glycine	301-304	pro-platelet basic protein	Homo sapiens	62-69
10419831-2	1999	In the present example, connective tissue-activating peptide (CTAPIII) and neutrophil-activating peptide 2 (NAP/2) were generated by digestion of a ubiquitin-CTAPIII conjugate with YUH1 and HIV Pr, respectively, as indicated below: [see text] YUH1 cleaved at the peptide bond formed by the C-terminal Gly(76) of ubiquitin (Ub) and the N-terminal Asn(1) of the 85-residue peptide CTAPIII.	Glycine	301-304	pro-platelet basic protein	Homo sapiens	75-106
10387080-1	1999	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to form glycine and single carbon groups that are essential for many biosynthetic pathways.	Glycine	91-98	serine hydroxymethyltransferase, cytosolic	Oryctolagus cuniculus	0-31
10387080-1	1999	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to form glycine and single carbon groups that are essential for many biosynthetic pathways.	Glycine	91-98	serine hydroxymethyltransferase, cytosolic	Oryctolagus cuniculus	33-37
10386589-3	1999	Cleavage sites were defined at the carboxy-terminal end of the fibrillin-1 proline-rich region and the corresponding fibrillin-2 glycine-rich region (exon 10), and within exon 49 towards the carboxy-terminus of fibrillin-1.	Glycine	129-136	fibrillin 2	Homo sapiens	117-128
10336496-5	1999	Two separate domains of nucleolin can interact with G-G-paired DNA, the four RNA binding domains and the C-terminal Arg-Gly-Gly repeats.	Glycine	120-123	nucleolin	Homo sapiens	24-33
10336496-5	1999	Two separate domains of nucleolin can interact with G-G-paired DNA, the four RNA binding domains and the C-terminal Arg-Gly-Gly repeats.	Glycine	124-127	nucleolin	Homo sapiens	24-33
10215884-3	1999	This finding is in agreement with previous conclusions that glycine in this position is essential for tight binding of cystatin A to cysteine proteinases by allowing optimal interaction of the N-terminal region of the inhibitor with the enzyme.	Glycine	60-67	cystatin A	Homo sapiens	119-129
10402203-4	1999	Mutation of either one of these two histidine residues (H42 and H44) in the extracellular N-terminal domain of NR2A shifted the IC50 for high-affinity Zn2+ inhibition approximately 200-fold without affecting the EC50 of the coagonists NMDA and glycine.	Glycine	244-251	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	111-115
10207026-2	1999	We have previously reported that the C terminus of NEDD8 is efficiently processed to expose Gly-76, which is required for conjugation to target proteins.	Glycine	92-95	NEDD8 ubiquitin like modifier	Homo sapiens	51-56
10222201-1	1999	The high-resolution X-ray structures have been determined for ten complexes formed between bovine beta-trypsin and P1 variants (Gly, Asp, Glu, Gln, Thr, Met, Lys, His, Phe, Trp) of bovine pancreatic trypsin inhibitor (BPTI).	Glycine	128-131	serine protease 1	Bos taurus	98-110
10092315-4	1999	Likewise, isosmotic cell swelling induced by insulin, ethanol, or glutamine/glycine activated p38(MAPK).	Glycine	76-83	mitogen activated protein kinase 14	Rattus norvegicus	94-97
10231019-3	1999	Histidine, cysteine and glycine were shown to block the effect of GAA.	Glycine	24-31	alpha glucosidase	Homo sapiens	66-69
10214957-5	1999	Since a Pro17 peptide-profilin II complex only partially restores actin polymerization, the glycine residues in the VASP peptide appear important.	Glycine	92-99	vasodilator stimulated phosphoprotein	Homo sapiens	116-120
10036231-2	1999	In situ hybridization data in rat brain suggested that it might also take up glycine and thus represent a general Vesicular Inhibitory Amino Acid Transporter (VIAAT).	Glycine	77-84	solute carrier family 32 member 1	Rattus norvegicus	114-157
10036231-2	1999	In situ hybridization data in rat brain suggested that it might also take up glycine and thus represent a general Vesicular Inhibitory Amino Acid Transporter (VIAAT).	Glycine	77-84	solute carrier family 32 member 1	Rattus norvegicus	159-164
10036231-7	1999	Pre-embedding detection of VIAAT followed by post-embedding detection of GABA or glycine on serial sections of the spinal cord or cerebellar cortex indicated that VIAAT was present in glycine-, GABA- or GABA- and glycine-containing boutons.	Glycine	81-88	solute carrier family 32 member 1	Rattus norvegicus	163-168
10036231-7	1999	Pre-embedding detection of VIAAT followed by post-embedding detection of GABA or glycine on serial sections of the spinal cord or cerebellar cortex indicated that VIAAT was present in glycine-, GABA- or GABA- and glycine-containing boutons.	Glycine	184-191	solute carrier family 32 member 1	Rattus norvegicus	163-168
10036231-7	1999	Pre-embedding detection of VIAAT followed by post-embedding detection of GABA or glycine on serial sections of the spinal cord or cerebellar cortex indicated that VIAAT was present in glycine-, GABA- or GABA- and glycine-containing boutons.	Glycine	184-191	solute carrier family 32 member 1	Rattus norvegicus	163-168
10331262-1	1999	Variation at the single-copy nuclear locus histone H3-D was surveyed in the diploid B-genome group of Glycine subgenus Glycine (Leguminosae: Papilionoideae), which comprises three named Australian species and a number of distinct but as yet not formally recognized taxa.	Glycine	102-109	H3 clustered histone 6	Homo sapiens	43-55
10331262-1	1999	Variation at the single-copy nuclear locus histone H3-D was surveyed in the diploid B-genome group of Glycine subgenus Glycine (Leguminosae: Papilionoideae), which comprises three named Australian species and a number of distinct but as yet not formally recognized taxa.	Glycine	119-126	H3 clustered histone 6	Homo sapiens	43-55
10440235-5	1999	In order to investigate this possibility, we have mutated the serines that are the sites of phosphorylation on the hsp27, to glycines or alanines.	Glycine	125-133	heat shock protein family B (small) member 1	Rattus norvegicus	115-120
9858599-1	1999	Genes encoding the Phe-Gly (FG) repeat-containing nucleoporins NUP98 and CAN/NUP214 are at the breakpoints of several chromosomal translocations associated with human acute myeloid leukemia (AML), but their role in oncogenesis is unclear.	Glycine	23-26	nucleoporin 98 and 96 precursor	Homo sapiens	63-68
10221600-3	1998	After treatment with carboxypeptidase B, the level of CCK Gly in Cpe(fat)/Cpe(fat) in these brain extracts was elevated to 33.5 ng/g, about 51-fold higher than in control.	Glycine	58-61	carboxypeptidase B1 (tissue)	Mus musculus	21-39
9817841-9	1998	CONCLUSIONS: The presence of the glycine-rich sequence in the fivefold channels of MVMi provides a possible mechanism to explain how the unique N-terminal region of VP1 becomes externalized in infectious parvovirions.	Glycine	33-40	hypothetical protein	Minute virus of mice	165-168
9858782-0	1998	Exposure of the cryptic Arg-Gly-Asp sequence in thrombospondin-1 by protein disulfide isomerase.	Glycine	28-31	prolyl 4-hydroxylase subunit beta	Bos taurus	68-95
9858782-13	1998	Treatment of thrombospondin-1 with purified protein disulfide isomerase enhanced adhesion of endothelial cells to thrombospondin-1 in an Arg-Gly-Asp-dependent manner through the alphav beta3 integrin receptor and supported cell spreading.	Glycine	141-144	prolyl 4-hydroxylase subunit beta	Bos taurus	44-71
9858782-15	1998	These results suggest that endothelial cell derived protein disulfide isomerase may regulate Arg-Gly-Asp-dependent binding of thrombospondin-1.	Glycine	97-100	prolyl 4-hydroxylase subunit beta	Bos taurus	52-79
9708551-7	1998	We conclude that 3-PGDH can be treated effectively by a combination of L-serine and glycine.	Glycine	84-91	phosphoglycerate dehydrogenase	Homo sapiens	17-23
9671971-7	1998	Characterization of the DM20 and PLP at 1 month of age showed that the amount of fatty acid (stearate and palmitate) was increased and the N-terminal glycine was methylated.	Glycine	150-157	proteolipid protein (myelin) 1	Mus musculus	24-28
9671971-7	1998	Characterization of the DM20 and PLP at 1 month of age showed that the amount of fatty acid (stearate and palmitate) was increased and the N-terminal glycine was methylated.	Glycine	150-157	proteolipid protein (myelin) 1	Mus musculus	33-36
9755023-3	1998	The purpose of this study was: (1) to investigate the effect of the anticonvulsant agent, milacemide, a glycine pro-drug on STR-allodynia; (2) to compare this effect with that of milacemide on normal nociception (without STR); and (3) to determine the sensitivity of the anti-allodynic effect of milacemide to pretreatment with selective monoamine oxidase (MAO)-A (clorgyline) and MAO-B (L-deprenyl) inhibitors.	Glycine	104-111	monoamine oxidase A	Rattus norvegicus	338-363
9627013-10	1998	The carboxyl-terminal Gly-Arg-Gly region of S10 protein is involved in constructing the cross-reactive epitope.	Glycine	30-33	ribosomal protein S10	Homo sapiens	44-47
9536084-3	1998	Mutations of the invariant glycine residues in the triple-helical domain-coding region of COL6A1 and COL6A2 have been reported previously in the chromosome 21-linked families.	Glycine	27-34	collagen type VI alpha 2 chain	Homo sapiens	101-107
9556603-2	1998	The binding site for the co-agonist glycine on N-methyl-D-aspartate (NMDA) receptors has been mapped to the NR1 subunit whereas binding of the principal agonist glutamate is mediated by the NR2 subunits.	Glycine	36-43	nodal homolog 2 L homeolog	Xenopus laevis	190-193
9556603-3	1998	Using the novel glycine site antagonist and photoaffinity label CGP 61594, distinct contributions of the NR2 subunit variants to the glycine antagonist binding domains of NMDA receptor subtypes are demonstrated.	Glycine	16-23	nodal homolog 2 L homeolog	Xenopus laevis	105-108
9556603-3	1998	Using the novel glycine site antagonist and photoaffinity label CGP 61594, distinct contributions of the NR2 subunit variants to the glycine antagonist binding domains of NMDA receptor subtypes are demonstrated.	Glycine	133-140	nodal homolog 2 L homeolog	Xenopus laevis	105-108
9556603-6	1998	Glycine antagonist sites with low and intermediate affinity for [3H]CGP 61594 were detected also in situ by radioligand binding in brain areas predominantly expressing the NR2A and NR2C subunits, respectively.	Glycine	0-7	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	172-176
9556603-6	1998	Glycine antagonist sites with low and intermediate affinity for [3H]CGP 61594 were detected also in situ by radioligand binding in brain areas predominantly expressing the NR2A and NR2C subunits, respectively.	Glycine	0-7	glutamate receptor, ionotropic, N-methyl D-aspartate 2C L homeolog	Xenopus laevis	181-185
9452416-5	1998	Covalent modification of PML requires the conserved Gly residue near the C termini of sentrin proteins.	Glycine	52-55	small ubiquitin like modifier 1	Homo sapiens	86-93
9442102-3	1998	SUMO-1 is linked to RanGAP1 via glycine 97, indicating that the last 4 amino acids of this 101- amino acid protein are proteolytically removed before its attachment to RanGAP1.	Glycine	32-39	small ubiquitin like modifier 1	Homo sapiens	0-6
9422722-6	1998	Mutations of Val-123, Leu-126, Gly-127, and Ile-128 affected the ability of PCNA to stimulate DNA synthesis by pol delta in several different assays.	Glycine	31-34	DNA polymerase delta 1, catalytic subunit	Homo sapiens	111-120
10806846-3	1998	The results showed that the three richest amino acids in HSP70 of all origins were Gly, Glu and Asp, except that of rat heart which was rich in Gly, Phe and Glu.	Glycine	83-86	heat shock protein family A (Hsp70) member 4	Rattus norvegicus	57-62
8558234-3	1996	Within 2-3 weeks after induction by retinoic acid, subsets of P19 and ES cells formed excitatory synapses, mediated by glutamate receptors, or inhibitory synapses, mediated by receptors for GABA or glycine.	Glycine	198-205	interleukin 23, alpha subunit p19	Mus musculus	62-65
8637723-0	1996	A nucleoside diphosphate kinase A (nm23-H1) serine 120--&gt;glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction.	Glycine	60-67	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	2-33
8637723-0	1996	A nucleoside diphosphate kinase A (nm23-H1) serine 120--&gt;glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction.	Glycine	60-67	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	35-42
8637723-2	1996	We have also found a serine 120--&gt;glycine substitution in NDPK A and/or amplification of the nm23-H1 gene in advanced stage neuroblastomas.	Glycine	37-44	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	61-67
8637723-4	1996	The effect of Ser120--&gt;Gly substitution on the biochemical properties of NDPK A was investigated.	Glycine	26-29	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	76-82
8637723-7	1996	Recombinant NDPK A containing the Ser120--&gt;Gly mutation exhibited reduced hexameric and increased dimeric oligomerization relative to the wild-type.	Glycine	46-49	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	12-18
8567620-2	1996	A gene encoding a single chain form of hIL5 dimer was constructed by linking the two hIL5 chain coding regions with Gly-Gly linker.	Glycine	116-119	interleukin 5	Homo sapiens	39-43
8567620-2	1996	A gene encoding a single chain form of hIL5 dimer was constructed by linking the two hIL5 chain coding regions with Gly-Gly linker.	Glycine	120-123	interleukin 5	Homo sapiens	39-43
9414160-3	1997	Here we show that the amino-terminal domain of PrPC exhibits five to six sites that bind copper (Cu(II)) presented as a glycine chelate.	Glycine	120-127	prion protein	Mus musculus	47-51
15094065-1	2004	The three genes hTAF(II)68, EWS, and TLS (called the TET family) encode related RNA binding proteins containing an RNA recognition motif and three glycine-, arginine-, and proline-rich regions in the C-terminus and a degenerated repeat containing the consensus sequence Ser-Tyr-Gly-Gln-Ser in the N-terminus.	Glycine	147-154	EWS RNA binding protein 1	Homo sapiens	28-31
9395513-2	1997	Cleavage within cells is mediated by furin, occurs between arginine 279 and glycine 280, and requires an arginine at both P1 and P4 residues.	Glycine	76-83	furin, paired basic amino acid cleaving enzyme	Homo sapiens	37-42
9548475-7	1997	Thus, the carboxyl-terminal five amino acids, Lys-Tyr-Glu-Gly-Lys (KYEGK), of the beta1 integrin cytoplasmic domain are critical for the coordinate tyrosine phosphorylation of three non-FAK substrates in human T cells.	Glycine	58-61	protein tyrosine kinase 2	Homo sapiens	186-189
15094065-1	2004	The three genes hTAF(II)68, EWS, and TLS (called the TET family) encode related RNA binding proteins containing an RNA recognition motif and three glycine-, arginine-, and proline-rich regions in the C-terminus and a degenerated repeat containing the consensus sequence Ser-Tyr-Gly-Gln-Ser in the N-terminus.	Glycine	278-281	EWS RNA binding protein 1	Homo sapiens	28-31
14729670-9	2004	The highly conserved glycines flanking the beta strand may act as pivot points, facilitating the conformational changes of Mor, and the DNA may be bent.	Glycine	21-29	Mor	Escherichia phage Mu	123-126
9353319-13	1997	Mutational analysis showed that the C terminus of NEDD8 was efficiently cleaved and that Gly-76 was required for conjugation of NEDD8 to other proteins.	Glycine	89-92	NEDD8 ubiquitin like modifier	Homo sapiens	128-133
9396534-6	1997	RESULTS: The galactose absorption, glycine absorption, DNA content, and protein content were significantly increased by EGF (69%, 28%, 64%, and 55%, respectively) and gastrin (72%, 60%, 93%, and 48%, respectively) when compared with control.	Glycine	35-42	epidermal growth factor like 1	Rattus norvegicus	120-123
9312102-2	1997	Using chimeric NR2A/NR2B subunits, we have located a region of NR2B (amino acids 138-238) which regulated glycine-independent polyamine stimulation.	Glycine	106-113	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	20-24
9312102-2	1997	Using chimeric NR2A/NR2B subunits, we have located a region of NR2B (amino acids 138-238) which regulated glycine-independent polyamine stimulation.	Glycine	106-113	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	63-67
7499425-3	1995	One type of LIM-domain protein, called the cysteine-rich protein (CRP), is characterized by the presence of two LIM domains linked to short glycine-rich repeats and a potential nuclear localization signal.	Glycine	140-147	C-reactive protein like 1	Gallus gallus	43-64
7499425-3	1995	One type of LIM-domain protein, called the cysteine-rich protein (CRP), is characterized by the presence of two LIM domains linked to short glycine-rich repeats and a potential nuclear localization signal.	Glycine	140-147	C-reactive protein like 1	Gallus gallus	66-69
14701845-3	2004	Subsequent mutagenesis revealed that Gly-15 (G15A) and Gly-18 (G18A) were critical for Cdc37-Cdk4 complex formation.	Glycine	37-40	cell division cycle 37, HSP90 cochaperone	Homo sapiens	87-92
7595540-2	1995	Five copies of the TRH progenitor sequence (Gln-His-Pro-Gly) and seven cryptic peptides are formed following posttranslational proteolytic cleavage of the 26-kDa rat proTRH precursor.	Glycine	56-59	thyrotropin releasing hormone	Rattus norvegicus	19-22
8613724-5	1995	The NMDA receptor modulators glycine and spermidine enhanced glutamate-mediated toxicity whereas ifenprodil potently and completely inhibited toxicity suggesting that the toxic response is mediated by the NR1/NR2B combination of NMDA subunits.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	209-213
9419055-1	1997	To investigate the spinal cellular structures and molecular mechanisms involved in acetylcholinesterase (AChE) release evoked by both glycine (GLY) and glutamate (GLU)--responses that might play a role in chronic neurotoxicity--we analysed AChE histochemistry and histology upon systemic administration of aspartate (ASP), and conducted in vitro experiments in synaptosomes and slices prepared from mouse spinal ventral horns.	Glycine	134-141	acetylcholinesterase	Mus musculus	105-109
9419055-1	1997	To investigate the spinal cellular structures and molecular mechanisms involved in acetylcholinesterase (AChE) release evoked by both glycine (GLY) and glutamate (GLU)--responses that might play a role in chronic neurotoxicity--we analysed AChE histochemistry and histology upon systemic administration of aspartate (ASP), and conducted in vitro experiments in synaptosomes and slices prepared from mouse spinal ventral horns.	Glycine	143-146	acetylcholinesterase	Mus musculus	105-109
9419055-3	1997	Histochemical reduction of motor neurone (MN) AChE, calcium dependency, decreases in intracellular AChE and the ratio amongst molecular forms released, suggest that both synaptosomal GLY-evoked AChE release (GLY-EAR) and GLU-receptor-elicited AChE release (GEAR) have release sites located at MN presynaptic terminals.	Glycine	183-186	acetylcholinesterase	Mus musculus	46-50
9419055-3	1997	Histochemical reduction of motor neurone (MN) AChE, calcium dependency, decreases in intracellular AChE and the ratio amongst molecular forms released, suggest that both synaptosomal GLY-evoked AChE release (GLY-EAR) and GLU-receptor-elicited AChE release (GEAR) have release sites located at MN presynaptic terminals.	Glycine	183-186	acetylcholinesterase	Mus musculus	99-103
9419055-3	1997	Histochemical reduction of motor neurone (MN) AChE, calcium dependency, decreases in intracellular AChE and the ratio amongst molecular forms released, suggest that both synaptosomal GLY-evoked AChE release (GLY-EAR) and GLU-receptor-elicited AChE release (GEAR) have release sites located at MN presynaptic terminals.	Glycine	183-186	acetylcholinesterase	Mus musculus	99-103
14701845-3	2004	Subsequent mutagenesis revealed that Gly-15 (G15A) and Gly-18 (G18A) were critical for Cdc37-Cdk4 complex formation.	Glycine	37-40	cyclin dependent kinase 4	Homo sapiens	93-97
9419055-3	1997	Histochemical reduction of motor neurone (MN) AChE, calcium dependency, decreases in intracellular AChE and the ratio amongst molecular forms released, suggest that both synaptosomal GLY-evoked AChE release (GLY-EAR) and GLU-receptor-elicited AChE release (GEAR) have release sites located at MN presynaptic terminals.	Glycine	183-186	acetylcholinesterase	Mus musculus	99-103
8521974-2	1995	The N-terminal glycine residue of retinal recoverin is heterogeneously acylated with myristoyl or related N-acyl group.	Glycine	15-22	recoverin	Homo sapiens	42-51
14701845-3	2004	Subsequent mutagenesis revealed that Gly-15 (G15A) and Gly-18 (G18A) were critical for Cdc37-Cdk4 complex formation.	Glycine	55-58	cell division cycle 37, HSP90 cochaperone	Homo sapiens	87-92
14701845-3	2004	Subsequent mutagenesis revealed that Gly-15 (G15A) and Gly-18 (G18A) were critical for Cdc37-Cdk4 complex formation.	Glycine	55-58	cyclin dependent kinase 4	Homo sapiens	93-97
14701845-4	2004	Gly-15 and Gly-18 of Cdk4 are within the conserved Gly-X-Gly-X-X-Gly motif that is required for ATP binding to the kinase.	Glycine	0-3	cyclin dependent kinase 4	Homo sapiens	21-25
8690179-1	1995	A heterozygous polymorphism changing GGT40 (Gly) to AGT40 (Ser) (Gly40Ser) in the glucagon receptor gene was reported to be associated with non-insulin-dependent diabetes mellitus (NIDDM).	Glycine	44-47	glucagon receptor	Homo sapiens	82-99
9337866-3	1997	A replacement of Gly with Ala in the cyclophilin-binding loop of HIV-1 Gag polyprotein results in the prevention of the packaging of Cyp18 into virions.	Glycine	17-20	Pr55(Gag)	Human immunodeficiency virus 1	71-74
14701845-4	2004	Gly-15 and Gly-18 of Cdk4 are within the conserved Gly-X-Gly-X-X-Gly motif that is required for ATP binding to the kinase.	Glycine	11-14	cyclin dependent kinase 4	Homo sapiens	21-25
14701845-5	2004	Mutation of either glycine at the equivalent positions of Raf1 (G358A and G361A) also inhibited Cdc37 binding to Raf1.	Glycine	19-26	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	58-62
14701845-5	2004	Mutation of either glycine at the equivalent positions of Raf1 (G358A and G361A) also inhibited Cdc37 binding to Raf1.	Glycine	19-26	cell division cycle 37, HSP90 cochaperone	Homo sapiens	96-101
14701845-5	2004	Mutation of either glycine at the equivalent positions of Raf1 (G358A and G361A) also inhibited Cdc37 binding to Raf1.	Glycine	19-26	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	113-117
15006370-3	2004	The active ICAM-1 peptides have a common Pro-Arg-Gly sequence that may be important for binding to LFA-1.	Glycine	49-52	integrin subunit alpha L	Homo sapiens	99-104
9239420-7	1997	Considered in the context of the high degree of structural preservation of glycine-treated tubule cells during ATP depletion and the commonly assumed Ca2+ requirements for phospholipid hydrolysis, actin disassembly, and Ca2+-mediated structural damage, the remarkable elevations of Caf demonstrated here suggest an unexpected resistance to the deleterious effects of increased Caf during energy deprivation in the presence of glycine.	Glycine	75-82	lysine acetyltransferase 2B	Homo sapiens	282-285
9239420-7	1997	Considered in the context of the high degree of structural preservation of glycine-treated tubule cells during ATP depletion and the commonly assumed Ca2+ requirements for phospholipid hydrolysis, actin disassembly, and Ca2+-mediated structural damage, the remarkable elevations of Caf demonstrated here suggest an unexpected resistance to the deleterious effects of increased Caf during energy deprivation in the presence of glycine.	Glycine	75-82	lysine acetyltransferase 2B	Homo sapiens	377-380
9269960-8	1997	Growth hormone-releasing hormone (GHRH) provocative tests (1 microg per rat, intravenously) showed the more significant elevation of growth hormone IGH) secretion in the arginine supplement group than that of glycine supplement group at 5 minutes (P &lt; .05).	Glycine	209-216	growth hormone releasing hormone	Rattus norvegicus	0-32
7556671-2	1995	Deduced from its nucleotide sequence, PDIR has the three CXXC-like motifs (Cys-Ser-Met-Cys, Cys-Gly-His-Cys and Cys-Pro-His-Cys), which are found in proteins within the PDI superfamily and are responsible for oxidoreductase activity.	Glycine	96-99	protein disulfide isomerase family A member 5	Homo sapiens	38-42
14722087-1	2004	Osteopontin (OPN) is a highly hydrophilic and negatively charged sialoprotein of approximately 298 amino acids that contains a Gly-Arg-Gly-Asp-Ser sequence.	Glycine	127-130	secreted phosphoprotein 1	Mus musculus	0-11
7654761-8	1995	N-Terminal amino acid sequencing showed that the 43K c-mos protein has a Asp-Glu-Gly-Gly-Asn-Leu-Gln-sequence located 5" upstream (99 bases upstream) of the rat c-mos coding sequence reported.	Glycine	81-84	MOS proto-oncogene, serine/threonine kinase	Rattus norvegicus	53-58
7654761-8	1995	N-Terminal amino acid sequencing showed that the 43K c-mos protein has a Asp-Glu-Gly-Gly-Asn-Leu-Gln-sequence located 5" upstream (99 bases upstream) of the rat c-mos coding sequence reported.	Glycine	85-88	MOS proto-oncogene, serine/threonine kinase	Rattus norvegicus	53-58
9271826-4	1997	The results show a significant increased frequency of two markers in membranous nephropathy patients as compared with controls: firstly the previously recognized increase in HLA-DR3 (59% vs 18%: Pc &lt; 1 x 10(-9), RR = 6.6), secondly a new association with two TAP1 amino acid variants displaying respectively a valine in amino acid position 333 (TAP1-Val-333) and consequently a glycine in position 637 (TAP1Gly-637) due to its strong linkage disequilibrium with Val-333.	Glycine	381-388	major histocompatibility complex, class II, DP beta 1	Homo sapiens	174-177
9218437-8	1997	The amino acid residues detected in insoluble elastin following hydrolysis with porcine pancreatic elastase and human neutrophil elastase were predominantly Gly and Ala, with lesser amounts of Val, Phe, Ile, and Leu.	Glycine	157-160	elastase, neutrophil expressed	Homo sapiens	118-137
14722087-1	2004	Osteopontin (OPN) is a highly hydrophilic and negatively charged sialoprotein of approximately 298 amino acids that contains a Gly-Arg-Gly-Asp-Ser sequence.	Glycine	127-130	secreted phosphoprotein 1	Mus musculus	13-16
7629143-8	1995	The adhesive motif RGDS (Arg-Gly-Asp-Ser) and an epidermal growth factor-like domain were identified.	Glycine	29-32	ral guanine nucleotide dissociation stimulator	Homo sapiens	19-23
14722087-1	2004	Osteopontin (OPN) is a highly hydrophilic and negatively charged sialoprotein of approximately 298 amino acids that contains a Gly-Arg-Gly-Asp-Ser sequence.	Glycine	135-138	secreted phosphoprotein 1	Mus musculus	0-11
14722087-1	2004	Osteopontin (OPN) is a highly hydrophilic and negatively charged sialoprotein of approximately 298 amino acids that contains a Gly-Arg-Gly-Asp-Ser sequence.	Glycine	135-138	secreted phosphoprotein 1	Mus musculus	13-16
9200463-7	1997	Internal deletion of the GFFKR motif, or point mutations of the Gly (G), the two Phe (F), or the Arg (R) in the GFFKR motif to Ala (A) rendered LFA-1 constitutively active.	Glycine	64-67	integrin subunit alpha L	Homo sapiens	144-149
14558884-6	2004	Mutation of Glu-60, a residue in the ATP-binding region of CaMKII, to glycine exerts different effects on phosphorylation of two peptide substrates, syntide and NR2B ( N -methyl-D-aspartate receptor subunit 2B) 17-mer.	Glycine	70-77	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	59-65
9202292-3	1997	Another case of RNA editing alters an arginine (R) to a glycine (G) codon at a position termed the "R/G" site of AMPA subunits GluR-B, C, and D. Double-stranded RNA-specific adenosine deaminases (DRADA) have been implicated as agents involved in the editing.	Glycine	56-63	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	127-133
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Glycine	54-57	myelin basic protein	Homo sapiens	141-161
14558884-6	2004	Mutation of Glu-60, a residue in the ATP-binding region of CaMKII, to glycine exerts different effects on phosphorylation of two peptide substrates, syntide and NR2B ( N -methyl-D-aspartate receptor subunit 2B) 17-mer.	Glycine	70-77	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	161-165
14558884-6	2004	Mutation of Glu-60, a residue in the ATP-binding region of CaMKII, to glycine exerts different effects on phosphorylation of two peptide substrates, syntide and NR2B ( N -methyl-D-aspartate receptor subunit 2B) 17-mer.	Glycine	70-77	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	168-209
7626124-2	1995	Comparison of the nucleotide sequence of its exon 7 with that of an ADH 7 previously cloned from a Japanese subject revealed a substitution of the glycine-287 in the Caucasian sigma isozyme with valine in the Japanese.	Glycine	147-154	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	Homo sapiens	68-73
7626124-4	1995	The exon 7 of the ADH 7 was amplified by PCR from 7 Caucasian and 7 Japanese genomic DNA and applied to restriction fragment length polymorphism analysis, using Ava II to digest the sequence encoding glycine-287 and Mae III to digest that encoding valine-287.	Glycine	200-207	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	Homo sapiens	18-23
9174192-6	1997	This enzyme differed from TEM-1 (blaT-1B gene) by four amino acid substitutions: Met--&gt;Leu-69, Glu--&gt;Lys-104, Gly--&gt;Ser-238 and Asn--&gt;Asp-276.	Glycine	116-119	hypothetical protein	Escherichia coli	26-31
9162015-4	1997	Transient expression of hemagglutinin epitope-tagged sentrin mutants in COS cells demonstrated that the sentrin C terminus is cleaved, which allows it to be conjugated to other proteins via the conserved C-terminal Gly residue.	Glycine	215-218	small ubiquitin like modifier 1	Homo sapiens	104-111
15037197-9	2004	Our results, using a yeast expression system, demonstrate that substituting glycine 154 of hENT1 with serine of hENT2 converts hENT1 to a transporter that exhibits partial characteristics of hENT2.	Glycine	76-83	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	91-96
15037197-9	2004	Our results, using a yeast expression system, demonstrate that substituting glycine 154 of hENT1 with serine of hENT2 converts hENT1 to a transporter that exhibits partial characteristics of hENT2.	Glycine	76-83	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	127-132
9169591-6	1997	With the aid of protein engineering, a modified pro-urokinase has been prepared in which the activation sequence normally recognized by plasmin (Pro-Arg-Phe-Lys upward arrowIle-Ile-Gly-Gly) has been replaced by a sequence expected to be recognized and hydrolysed by many MMPs (Arg-Pro-Leu-Gly upward arrowIle-Ile-Gly-Gly).	Glycine	181-184	plasminogen	Homo sapiens	136-143
9169591-6	1997	With the aid of protein engineering, a modified pro-urokinase has been prepared in which the activation sequence normally recognized by plasmin (Pro-Arg-Phe-Lys upward arrowIle-Ile-Gly-Gly) has been replaced by a sequence expected to be recognized and hydrolysed by many MMPs (Arg-Pro-Leu-Gly upward arrowIle-Ile-Gly-Gly).	Glycine	185-188	plasminogen	Homo sapiens	136-143
14701904-2	2004	Mammalian cellular retinoic acid-binding protein I (CRABP I) was mutated to incorporate in a surface-exposed omega loop the sequence Cys-Cys-Gly-Pro-Cys-Cys, which binds specifically to a biarsenical fluorescein dye (FlAsH).	Glycine	141-144	cellular retinoic acid binding protein 1	Homo sapiens	10-50
9169591-6	1997	With the aid of protein engineering, a modified pro-urokinase has been prepared in which the activation sequence normally recognized by plasmin (Pro-Arg-Phe-Lys upward arrowIle-Ile-Gly-Gly) has been replaced by a sequence expected to be recognized and hydrolysed by many MMPs (Arg-Pro-Leu-Gly upward arrowIle-Ile-Gly-Gly).	Glycine	185-188	plasminogen	Homo sapiens	136-143
9169591-6	1997	With the aid of protein engineering, a modified pro-urokinase has been prepared in which the activation sequence normally recognized by plasmin (Pro-Arg-Phe-Lys upward arrowIle-Ile-Gly-Gly) has been replaced by a sequence expected to be recognized and hydrolysed by many MMPs (Arg-Pro-Leu-Gly upward arrowIle-Ile-Gly-Gly).	Glycine	185-188	plasminogen	Homo sapiens	136-143
9169591-6	1997	With the aid of protein engineering, a modified pro-urokinase has been prepared in which the activation sequence normally recognized by plasmin (Pro-Arg-Phe-Lys upward arrowIle-Ile-Gly-Gly) has been replaced by a sequence expected to be recognized and hydrolysed by many MMPs (Arg-Pro-Leu-Gly upward arrowIle-Ile-Gly-Gly).	Glycine	185-188	plasminogen	Homo sapiens	136-143
7625831-1	1995	Activity of glycine decarboxylase decreased by 60-70% after the isolated pea leaf mitochondria were aged for 5 h in the absence of glycine and was completely lost after 24 h. The reverse reaction, i.e., production of glycine from serine, ammonium, dihydrolipoate, and bicarbonate, was also inhibited in these aged mitochondria.	Glycine	131-138	glycine decarboxylase	Homo sapiens	12-33
14701904-2	2004	Mammalian cellular retinoic acid-binding protein I (CRABP I) was mutated to incorporate in a surface-exposed omega loop the sequence Cys-Cys-Gly-Pro-Cys-Cys, which binds specifically to a biarsenical fluorescein dye (FlAsH).	Glycine	141-144	cellular retinoic acid binding protein 1	Homo sapiens	52-59
9130696-8	1997	Co-immunoprecipitation studies coupled with analysis by mass spectrometry show that release of the propeptide at acidic pH, and hence activation of furin, requires a second cleavage within the autoinhibitory domain at a site containing a P6 arginine (-Arg70-Gly-Val-Thr-Lys-Arg75/-).	Glycine	258-261	furin, paired basic amino acid cleaving enzyme	Homo sapiens	148-153
15356744-3	2004	Crystal structures of nine chelated YbL1-amino acid adducts (Gly, Ala, Ser, Thr, Met) confirm this.	Glycine	61-64	DNA polymerase epsilon 3, accessory subunit	Homo sapiens	36-40
9148753-5	1997	The N-terminal sequence of the two fragments generated by MMP-2 and MMP-3 is Leu211-Lys-Gly-Leu-Asn, but that of the others is Asp1-Glu-Ala-Ser-Gly.	Glycine	88-91	matrix metallopeptidase 2	Homo sapiens	58-63
9148753-5	1997	The N-terminal sequence of the two fragments generated by MMP-2 and MMP-3 is Leu211-Lys-Gly-Leu-Asn, but that of the others is Asp1-Glu-Ala-Ser-Gly.	Glycine	144-147	matrix metallopeptidase 2	Homo sapiens	58-63
7677850-10	1995	The glycine mutant of FNR displays behavior intermediate between that of wild-type enzyme and that of the valine mutant.	Glycine	4-11	ferredoxin reductase	Homo sapiens	22-25
15020418-10	2004	Last, our analysis implicates glycine 160 of the second LRR in regulating EGFR binding.	Glycine	30-37	Epidermal growth factor receptor	Drosophila melanogaster	74-78
7670372-4	1995	Through the analysis of known barrel structures we developed a topographic model of the pyridoxal phosphate-binding domain of ornithine decarboxylase, which predicts that the Schiff base lysine and a conserved glycine-rich sequence both map to the C-termini of the beta-strands.	Glycine	210-217	ornithine decarboxylase 1	Homo sapiens	126-149
9123849-4	1997	It was found that the Gly-to-Ala mutation in the BH1 domain of the viral protein abolished its capacity to protect the K562 cells from apoptosis, indicating that this Gly is essential for A179L action.	Glycine	22-25	bcl-2/bax homolog	African swine fever virus	188-193
9123849-4	1997	It was found that the Gly-to-Ala mutation in the BH1 domain of the viral protein abolished its capacity to protect the K562 cells from apoptosis, indicating that this Gly is essential for A179L action.	Glycine	167-170	bcl-2/bax homolog	African swine fever virus	188-193
15176218-5	2004	In the same patients, receptor-negative tumors occurred more often (p = 0.032) than in combinations of higher level of 4-hydroxylase estradiol of S-allele in position 48 (Gly/Arg) of the CYP1B1 gene.	Glycine	171-174	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	187-193
9020125-5	1997	Following stimulation of the cultures with glutamate/glycine or phorbol esters, NR1 phosphorylation was found to be enhanced by 3-5-fold, whereas phosphorylation of NR2 subunits was enhanced by less than 2-fold.	Glycine	53-60	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	80-83
7794272-7	1995	A similar ser120-gly mutation in NME1 has been found in human neuroblastoma, suggesting that mutation in this region may be a general phenomenon related to tumor progression.	Glycine	17-20	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	33-37
7538175-7	1995	However, the sequence Asp-Lys-Gly-Gly (amino acids 44 to 47), also found in the B subunit of PP2A, is dispensable for complex formation between MT and PP2A.	Glycine	30-33	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	Mus musculus	93-97
7538175-7	1995	However, the sequence Asp-Lys-Gly-Gly (amino acids 44 to 47), also found in the B subunit of PP2A, is dispensable for complex formation between MT and PP2A.	Glycine	34-37	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	Mus musculus	93-97
8895525-3	1996	By deletion analysis, the transactivation domains of HOX-11 have been mapped to three amino acid stretches in the homeoprotein, the glycine-proline-rich region at the amino terminus, the homeodomain and the glutamine-rich region at the carboxyl terminus.	Glycine	132-139	T cell leukemia homeobox 1	Homo sapiens	53-59
14503883-1	2003	Replacement of the three N-terminal residues preceding the conserved Gly of cystatin A by the corresponding 10-residue long segment of cystatin C increased the affinity of the inhibitor for the major lysosomal cysteine proteinase, cathepsin B, by approximately 15-fold.	Glycine	69-72	cystatin A	Homo sapiens	76-86
8906592-4	1996	This novel mutation (G181X) was a G-to-T substitution at codon 181 of exon 6 which replaced a codon for glycine (GGA) with a premature stop codon (TGA).	Glycine	104-111	T-box transcription factor 1	Homo sapiens	147-150
8768735-6	1996	Receptors resulting from injection of hNMDAR1A, hNMDAR2A and hNMDAR2B transcripts in a 1:1:1 ratio were indistinguishable from hNMDAR1A/2B receptors in terms of their sensitivity to NMDA, glycine, D-serine, CGS 19755 and CGP 40116.	Glycine	188-195	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	61-69
7742369-4	1995	Interestingly, the carboxyl-terminus sequence EEEGEEY (Glu-Glu-Glu-Gly-Glu-Glu-Tyr) of the nematode tba-1 encoded isotype is identical to these residues in human, mouse, rat, pig and chicken alpha-1 tubulin isotypes that are expressed in the brain.	Glycine	67-70	Tubulin alpha chain	Caenorhabditis elegans	100-105
12810727-4	2003	We show here that recombinant hBACAT also can hydrolyze long- and very long-chain saturated acyl-CoAs (mainly C16:0-C26:0) and by mass spectrometry verified that hBACAT also conjugates fatty acids to glycine.	Glycine	200-207	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	30-36
8843097-2	1996	The specific mu-receptor opioid agonist, Tyr, D-Ala2, Gly, N-Me-Phe4, Gly-ol5 (DAMGO), was found to increase AP-1 and NF-kappa B activity in primary cultures of neurons from rat cerebral cortex.	Glycine	54-57	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	109-113
12810727-4	2003	We show here that recombinant hBACAT also can hydrolyze long- and very long-chain saturated acyl-CoAs (mainly C16:0-C26:0) and by mass spectrometry verified that hBACAT also conjugates fatty acids to glycine.	Glycine	200-207	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	162-168
12969432-8	2003	Using a multiscale docking algorithm in combination with a molecular model of the ligand-binding domain of plant GLRs, evidence is provided indicating that glycine, and not glutamate, is likely to be the natural ligand for most plant GLR subunits.	Glycine	156-163	glucagon receptor	Homo sapiens	113-116
8672473-6	1996	The second carboxylate group of glutathione, which is part of its Gly residue, interacts with two Arg side chains in GST A1-1.	Glycine	66-69	glutathione S-transferase alpha 1	Homo sapiens	117-125
8639838-1	1996	A new type of gamma Gly-268 (GGA) to Glu (GAA) substitution has been identified in a homozygous dysfibrinogen by analyses of the affected polypeptide and its encoding gene derived from a 58 year-old man manifesting no major bleeding or thrombosis.	Glycine	20-23	alpha glucosidase	Homo sapiens	42-45
7542253-0	1995	Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions.	Glycine	42-49	secreted phosphoprotein 1	Mus musculus	76-87
7890717-6	1995	MMP-2 cleaves at the same Gly-Ile/Leu bond in the collagen alpha chains as interstitial collagenases with kcat and Km values similar to that of MMP-1.	Glycine	26-29	matrix metallopeptidase 2	Homo sapiens	0-5
12908799-0	2003	Hb Bronte or alpha93(FG5)Val-->Gly: a new unstable variant of the alpha2-globin gene, associated with a mild alpha(+)-thalassemia phenotype.	Glycine	31-34	hemoglobin subunit alpha 2	Homo sapiens	66-79
7890672-6	1995	These residues include Gly-30 and Asp-49, which are conserved in all sPLA2s.	Glycine	23-26	phospholipase A2 group IID	Homo sapiens	69-75
8725286-4	1996	Inhibition of fibronectin matrix formation by the inclusion of Arg-Gly-Asp-containing peptides, which compete with fibronectin for binding to the cell surface alpha 5 beta 1 integrin receptors, abolished the proliferation effects of FGF-2.	Glycine	67-70	fibroblast growth factor 2	Gallus gallus	233-238
12808093-4	2003	In addition, a mutant of PED/PEA-15 featuring the substitution of Ser(116)--&gt;Gly (PED(S116--&gt;G)) showed 10-fold-decreased phosphorylation by Akt.	Glycine	80-83	OCA2 melanosomal transmembrane protein	Homo sapiens	25-28
7887904-0	1995	Probing the functional role of the N-terminal region of cystatins by equilibrium and kinetic studies of the binding of Gly-11 variants of recombinant human cystatin C to target proteinases.	Glycine	119-122	cystatin C	Homo sapiens	156-166
12808093-4	2003	In addition, a mutant of PED/PEA-15 featuring the substitution of Ser(116)--&gt;Gly (PED(S116--&gt;G)) showed 10-fold-decreased phosphorylation by Akt.	Glycine	80-83	OCA2 melanosomal transmembrane protein	Homo sapiens	85-88
8727230-5	1996	A recent study in a Japanese subject found a point mutation in the codon for amino acid 287 of the ADH7 gene (which encodes sigma-ADH), changing the amino acid from glycine to valine.	Glycine	165-172	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	Homo sapiens	99-103
8727230-5	1996	A recent study in a Japanese subject found a point mutation in the codon for amino acid 287 of the ADH7 gene (which encodes sigma-ADH), changing the amino acid from glycine to valine.	Glycine	165-172	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	Homo sapiens	124-133
12702816-4	2003	We have used a biochemical genomics approach with a collection of purified yeast GST-ORF fusion proteins to show that m(1)G(9) formation of yeast tRNA(Gly) is associated with ORF YOL093w, named TRM10.	Glycine	151-154	tRNA (guanine(9)-N(1))-methyltransferase	Saccharomyces cerevisiae S288C	194-199
8786430-2	1996	Tat proteins containing mutations in the Arg-Gly-Asp (RGD) cell adhesion motif or a deletion of the cysteine-rich domain had no effect on neuronal morphology.	Glycine	45-48	tyrosine aminotransferase	Homo sapiens	0-3
7769000-1	1995	hnRNP A1 (34 kDa) is an RNA binding protein consisting of two tandemly arranged RNA binding domains C-terminally linked to a glycine-rich auxiliary domain (2 x RBD-Gly).	Glycine	125-132	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	0-8
7769000-1	1995	hnRNP A1 (34 kDa) is an RNA binding protein consisting of two tandemly arranged RNA binding domains C-terminally linked to a glycine-rich auxiliary domain (2 x RBD-Gly).	Glycine	164-167	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	0-8
12702816-6	2003	Yeast Trm10p purified from E. coli quantitatively modifies the G(9) position of tRNA(Gly) in an S-adenosylmethionine-dependent fashion.	Glycine	85-88	tRNA (guanine(9)-N(1))-methyltransferase	Saccharomyces cerevisiae S288C	6-12
12702816-7	2003	Trm10p is responsible in vivo for most if not all m(1)G(9) modification of tRNAs, based on two results: tRNA(Gly) purified from a trm10-Delta/trm10-Delta strain is lacking detectable m(1)G; and a primer extension block occurring at m(1)G(9) is removed in trm10-Delta/trm10-Delta-derived tRNAs for all 9 m(1)G(9)-containing species that were testable by this method.	Glycine	109-112	tRNA (guanine(9)-N(1))-methyltransferase	Saccharomyces cerevisiae S288C	0-6
8788089-4	1996	Na(+)-independent transporters of glutamate, glutamine and glycine (including system asc) display an opposite modulation in activity, which may help to combat amino-acid-induced oxidative stress by increasing the supply of glutathione precursors.	Glycine	59-66	PYD and CARD domain containing L homeolog	Xenopus laevis	85-88
12562776-2	2003	Substitution of Arg(440) in IL5 with other residues except positively charged Lys caused a large shift in pH(i) dependence of (22)Na(+) uptake to an acidic side, whereas substitution of Gly(455) or Gly(456) within the highly conserved glycine-rich sequence of TM11 shifted pH(i) dependence to an alkaline side.	Glycine	235-242	interleukin 5	Homo sapiens	28-31
8815211-13	1996	Channels in which the NR1 N-site asparagine was replaced by the smaller glycine (G), NR1(N598G)-NR2A, showed the largest increase in pore size of all sites examined in either subunit.	Glycine	72-79	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	96-100
12579557-4	2003	RGDS (Arg-Gly-Asp-Ser) peptide immobilization onto PE film resulted in almost the same differentiation activity as the collagen immobilized PE film.	Glycine	10-13	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	0-4
8815211-14	1996	In contrast, in the NR2A-subunit the same N-site substitution to glycine produced only small effects on pore size.	Glycine	65-72	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	20-24
8631326-6	1996	Protein mass fingerprinting with tryptic fragments identified p57 as a protein related to protein disulfide-isomerase which belongs to the superfamily of Cys-Gly-His-Cys-containing sequences.	Glycine	158-161	cyclin-dependent kinase inhibitor 1C	Rattus norvegicus	62-65
7827057-7	1995	As in other parvalbumins, the liganding residues in the CD and EF sites of oncomodulin differ at the +z and -x coordination positions: serine and aspartate, respectively, in the CD site; aspartate and glycine in the EF site.	Glycine	201-208	oncomodulin	Homo sapiens	75-86
12540830-4	2003	In the cavity of Aro4p at position 226 is a glycine residue, which is highly conserved in all other tyrosine-regulated DAHP synthases as well.	Glycine	44-51	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	17-22
8643384-6	1995	We found that the highly conserved RRM and glycine rich domains of Snp1 were not required for complementation of the snp1-null growth or splicing defects.	Glycine	43-50	U1 snRNP complex subunit SNP1	Saccharomyces cerevisiae S288C	67-71
8550581-2	1996	Inclusion of CoCl2 during the purification of recombinant UCRP blocks the proteolytic inactivation of the polypeptide occurring by cleavage of the carboxyl-terminal glycine dipeptide required for activation and subsequent ligation.	Glycine	165-172	ISG15 ubiquitin like modifier	Homo sapiens	58-62
12544342-2	2003	Glyoxylate is enzymatically converted to glycine by alanine-glyoxylate aminotransferase in the liver and vitamin B6 has a key role as a coenzyme.	Glycine	41-48	alanine--glyoxylate and serine--pyruvate aminotransferase	Rattus norvegicus	52-87
8624397-1	1996	This in vitro study was an investigation of osteoblast functions on glass substrates modified with the bioactive peptide Arg-Gly-Asp-Ser (RGDS) in the absence and presence of recombinant human Osteogenic Protein-1 (OP-1); control substrates were plain glass, glass modified with amine groups, and glass modified with the non-adhesive peptide Arg-Asp-Gly-Ser.	Glycine	125-128	ral guanine nucleotide dissociation stimulator	Homo sapiens	138-142
7947821-1	1994	The primary structure of galectin-3, a approximately 30 kDa galactoside-binding protein (aka CBP-35, mL-34, hL-31, L-29, Mac-2, and epsilon BP), reveals two structural domains: an amino-terminal domain consists of a Pro-Gly-rich motif, and a globular carboxyl-terminal domain containing a carbohydrate-binding site.	Glycine	220-223	galectin 3	Homo sapiens	25-35
12578541-4	2003	DB1 cells produced 38 kDa CTGF and low molecular mass CTGFs that had N-termini between modules 2 and 3 at Ala(181) (20 kDa), Leu(184) (18 kDa) or Ala(197) (16 kDa) or between modules 3 and 4 at Gly(253) (10 kDa).	Glycine	194-197	vascular endothelial zinc finger 1	Homo sapiens	0-3
7965099-5	1994	This effect was mimicked by (2S,1"S,2"S)-2-(carboxycyclopropyl)glycine (L-CCG-I), a selective agonist of mGluR2/R3 receptors, but not by quisqualate at a concentration that stimulated inositol phosphate (InsP) synthesis, showing that mGluR1 and mGluR5 did not participate to this mechanism.	Glycine	62-70	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	105-111
7965099-5	1994	This effect was mimicked by (2S,1"S,2"S)-2-(carboxycyclopropyl)glycine (L-CCG-I), a selective agonist of mGluR2/R3 receptors, but not by quisqualate at a concentration that stimulated inositol phosphate (InsP) synthesis, showing that mGluR1 and mGluR5 did not participate to this mechanism.	Glycine	62-70	glutamate metabotropic receptor 1	Homo sapiens	234-240
7965099-5	1994	This effect was mimicked by (2S,1"S,2"S)-2-(carboxycyclopropyl)glycine (L-CCG-I), a selective agonist of mGluR2/R3 receptors, but not by quisqualate at a concentration that stimulated inositol phosphate (InsP) synthesis, showing that mGluR1 and mGluR5 did not participate to this mechanism.	Glycine	62-70	glutamate receptor, ionotropic, kainate 1	Mus musculus	245-251
12438316-1	2003	Serine hydroxymethyltransferase (SHMT; EC 2.1.2.1) catalyzes the reversible interconversion of serine and glycine with transfer of the serine side chain one-carbon group to tetrahydropteroylglutamate (H(4)PteGlu), and also the conversion of 5,10-methenyl-H(4)PteGlu to 5-formyl-H(4)PteGlu.	Glycine	106-113	serine hydroxymethyltransferase, cytosolic	Oryctolagus cuniculus	0-31
7945384-5	1994	PLC-alpha is supposed to be a member not of PLC superfamily but of Trp-Cys-Gly-His-Cys-Lys motif-containing proteins consisting of protein disulfide isomerase, P5, ERp72, and thioredoxin.	Glycine	75-78	thioredoxin	Bos taurus	175-186
12438316-1	2003	Serine hydroxymethyltransferase (SHMT; EC 2.1.2.1) catalyzes the reversible interconversion of serine and glycine with transfer of the serine side chain one-carbon group to tetrahydropteroylglutamate (H(4)PteGlu), and also the conversion of 5,10-methenyl-H(4)PteGlu to 5-formyl-H(4)PteGlu.	Glycine	106-113	serine hydroxymethyltransferase, cytosolic	Oryctolagus cuniculus	33-37
12866360-6	2003	GPLGV pentapeptide was used as a substrate for MMP-2 and MMP-9, where the cleavage of Gly-Val bond by MMP was expected.	Glycine	86-89	matrix metallopeptidase 9	Mus musculus	57-62
7765520-3	1994	The estimated molecular size of GRP was approximately 30 kDa and GRP contained 59% glycine and 15% serine.	Glycine	83-90	glycine-rich RNA-binding protein	Glycine max	65-68
12417259-5	2002	When a MARCKS (myristoylated alanine-rich C-kinase substrate)-derived peptide substrate (Gly-Ala-Gln-Phe-Ser-Lys-Thr-Ala-Arg-Arg) and the M2 gene segment of the reovirus type 3 peptide substrate (Gly-Asn-Ala-Ser-Ser-Ile-Lys-Lys-Lys) were used, hNMT activity was increased by approximately 8.5- and 7-fold, respectively.	Glycine	196-199	myristoylated alanine rich protein kinase C substrate	Homo sapiens	7-13
8090720-0	1994	Regulation of scallop myosin by the regulatory light chain depends on a single glycine residue.	Glycine	79-86	myosin, heavy chain 15	Gallus gallus	22-28
12215427-6	2002	Deletion of the Gly-76 residue in the carboxyl terminus of Nedd8 abolished this effect and prevented AhR-Nedd8 interaction.	Glycine	16-19	neural precursor cell expressed, developmentally down-regulated gene 8	Mus musculus	59-64
12215427-6	2002	Deletion of the Gly-76 residue in the carboxyl terminus of Nedd8 abolished this effect and prevented AhR-Nedd8 interaction.	Glycine	16-19	neural precursor cell expressed, developmentally down-regulated gene 8	Mus musculus	105-110
12145314-3	2002	The autocatalytic degradation product is a cell surface 44-kDa fragment of MT1-MMP (Gly(285)-Val(582)) in which the ectodomain consists of only the linker, hemopexin C domain and the stalk segment found before the transmembrane sequence.	Glycine	84-87	matrix metallopeptidase 14	Homo sapiens	75-82
8077215-6	1994	The corresponding residues in lysosomal acid phosphatase (LAP) are Lys and Gly.	Glycine	75-78	acid phosphatase 2, lysosomal	Homo sapiens	30-56
8077215-6	1994	The corresponding residues in lysosomal acid phosphatase (LAP) are Lys and Gly.	Glycine	75-78	acid phosphatase 2, lysosomal	Homo sapiens	58-61
7520836-6	1994	The mutations included replacement of the human CD8 alpha CDR1- and CDR2-like loops by the homologous mouse sequences and the insertion of a glycine in the middle of the CDR3-like loop.	Glycine	141-148	CDR3	Homo sapiens	170-174
12145314-3	2002	The autocatalytic degradation product is a cell surface 44-kDa fragment of MT1-MMP (Gly(285)-Val(582)) in which the ectodomain consists of only the linker, hemopexin C domain and the stalk segment found before the transmembrane sequence.	Glycine	84-87	hemopexin	Homo sapiens	156-165
12392761-4	2002	The recombinant human ADAM-TS5, like ADAM-TS4 cleaves aggrecan at Glu(1480)-Gly(1481), Glu(1667)-Gly(1668), Glu(1771)-Ala(1772) and Glu(1871)-Leu(1872) bonds more readily than at the Glu(373)-Ala(374) bond.	Glycine	76-79	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	37-45
7837972-2	1994	A construct was made from a plasmid in which the active-site serine of beta-lactamase was substituted by glycine by site-directed mutation.	Glycine	105-112	Bla	Salmonella enterica subsp. enterica serovar Typhimurium	71-85
12392761-4	2002	The recombinant human ADAM-TS5, like ADAM-TS4 cleaves aggrecan at Glu(1480)-Gly(1481), Glu(1667)-Gly(1668), Glu(1771)-Ala(1772) and Glu(1871)-Leu(1872) bonds more readily than at the Glu(373)-Ala(374) bond.	Glycine	97-100	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	37-45
8063713-5	1994	The first of these substrates, NFF-1 (Mca-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Lys-(Dnp)-Gly, where Mca is (7-methoxycoumarin-4-yl)acetyl and Dnp is 2,4-dinitrophenyl), was hydrolyzed equally well by MMP-3 and MMP-2 (kcat/Km approximately 11,000 s-1 M-1).	Glycine	70-73	matrix metallopeptidase 2	Homo sapiens	209-214
12021263-1	2002	Serine racemase (SR) is a brain enzyme present in glial cells, where it isomerizes L-serine into D-serine that, in turn, diffuses and coactivates the N-methyl-D-aspartate receptor through the binding to the so-called "glycine site."	Glycine	218-225	serine racemase	Homo sapiens	0-15
8051088-4	1994	The purified venom mucin comprised about 85% carbohydrate and 15% protein and was rich in Thr, Ser, Pro, Gly, Glu, Asp, and Ala.	Glycine	105-108	LOC100508689	Homo sapiens	19-24
12021263-1	2002	Serine racemase (SR) is a brain enzyme present in glial cells, where it isomerizes L-serine into D-serine that, in turn, diffuses and coactivates the N-methyl-D-aspartate receptor through the binding to the so-called "glycine site."	Glycine	218-225	serine racemase	Homo sapiens	17-19
12112533-5	2002	The NUP98-HOXA13 fusion protein consists of the N-terminal phenylalanine-glycine repeat motif of NUP98 and the C-terminal homeodomain of HOXA13, similar to the NUP98-HOXA9 fusion protein.	Glycine	73-80	nucleoporin 98 and 96 precursor	Homo sapiens	4-9
8052270-8	1994	Position 615 is glutamic acid in UVL-13 and glycine in AA8, and the corresponding positions of XPD, RAD3, and rad15 are glycine.	Glycine	120-127	general transcription and DNA repair factor IIH helicase subunit XPD	Cricetulus griseus	95-98
12047194-1	2002	The DC electric susceptibilities of unsolvated glycine-based peptides, WGn (W = tryptophan and G = glycine) with n = 1-5, have been measured by deflection of a molecular beam in an electric field.	Glycine	47-54	versican	Homo sapiens	71-74
8034645-5	1994	On the other hand, a dansyl-Glu-Gly-Arg chloromethyl ketone-treated Gla-domainless VIIa (Ki = 0.7 x 10(-7) M) showed a high affinity for TF, whereas the corresponding Gla-domainless VII similarly treated showed no binding potential, thereby indicating that binding site(s) other than in the Gla-EGF1 region are present in VIIa but not in VII.	Glycine	32-35	LOC101909187	Bos taurus	137-139
12068077-2	2002	The inhibition constants (K (I) s) for the binding of l-glutamate and glycine to NR1-1a/NR2A determined by [3 H]CGP 39653 and [3 H]MDL 105 519 displacement assays, respectively, were not significantly different between NR1-1a/NR2A receptors coexpressed +/- PSD-95(c-Myc).	Glycine	70-77	discs large MAGUK scaffold protein 4	Homo sapiens	257-263
8045411-2	1994	Although CAJ1 contains neither a Gly-rich region nor a Cys-rich repeat, as are found in other DnaJ relatives, it contains a leucine zipper-like motif.	Glycine	33-36	Caj1p	Saccharomyces cerevisiae S288C	9-13
11962665-2	2002	In the results of X-ray diffraction analysis, HAp synthesized in the presence of glycine (HAp-Gly), serine (HAp-Ser), aspartic acid (HAp-Asp) and glutamic acid (HAp-Glu) showed poor crystallinity compared with HAp synthesized in the absence of amino acid (HAp-con).	Glycine	81-88	reticulon 3	Homo sapiens	46-49
11962665-2	2002	In the results of X-ray diffraction analysis, HAp synthesized in the presence of glycine (HAp-Gly), serine (HAp-Ser), aspartic acid (HAp-Asp) and glutamic acid (HAp-Glu) showed poor crystallinity compared with HAp synthesized in the absence of amino acid (HAp-con).	Glycine	94-97	reticulon 3	Homo sapiens	46-49
7807141-4	1994	Strychnine-resistant glycine stimulation potentiated glutamate-induced AChE release, suggesting N-methyl-D-aspartate (NMDA) receptor involvement.	Glycine	21-28	acetylcholinesterase	Mus musculus	71-75
11943330-2	2002	The extracellular domain of SLA-I was connected to porcine beta2 microglobulin by glycine-rich linkers.	Glycine	82-89	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	59-64
7974465-2	1994	DQA1*0104 has a guanine in the second position of the second expressed codon, whereas DQA1*0101 and all other sequenced DQA1 alleles have an adenine in that position, changing aspartic acid to glycine.	Glycine	193-200	major histocompatibility complex, class II, DQ alpha 1	Homo sapiens	0-4
12036068-0	2002	Salts and glycine increase reversibility and decrease aggregation during thermal unfolding of ribonuclease-A.	Glycine	10-17	ribonuclease A family member 1, pancreatic	Homo sapiens	94-108
7974465-2	1994	DQA1*0104 has a guanine in the second position of the second expressed codon, whereas DQA1*0101 and all other sequenced DQA1 alleles have an adenine in that position, changing aspartic acid to glycine.	Glycine	193-200	major histocompatibility complex, class II, DQ alpha 1	Homo sapiens	86-90
7974465-2	1994	DQA1*0104 has a guanine in the second position of the second expressed codon, whereas DQA1*0101 and all other sequenced DQA1 alleles have an adenine in that position, changing aspartic acid to glycine.	Glycine	193-200	major histocompatibility complex, class II, DQ alpha 1	Homo sapiens	86-90
12036068-6	2002	These results demonstrate that aggregation makes thermal unfolding of RNase-A at least partially irreversible and salts and glycine increase reversibility and decrease aggregation.	Glycine	124-131	ribonuclease A family member 1, pancreatic	Homo sapiens	70-77
11877666-8	2002	Rats treated with systemic IL-11 showed improved absorption of galactose of 2.39 micromoles/cm(2) (P &lt;.05), and glycine at 2.21 micromoles/cm(2) (P &lt;.05).	Glycine	115-122	interleukin 11	Rattus norvegicus	27-32
8016122-5	1994	Therefore, the segments Ile-163-Gly-354 and Lys-712-Ser-830 of the SERCA1 ATPase are sufficient for Ca2+ and thapsigargin sensitivity.	Glycine	32-35	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	Gallus gallus	67-73
7948575-1	1994	A cell adhesive peptide, Arg-Gly-Asp-Ser (RGDS), enhances leucocyte response to stimuli when insolubilized or conjugated with proteins.	Glycine	29-32	ral guanine nucleotide dissociation stimulator	Homo sapiens	42-46
8886580-7	1996	Portal plasma displayed a small postprandial increase in the concentration of glycine-extended gastrin, but extraction over the liver and gut remained nonsignificant.	Glycine	78-85	gastrin	Sus scrofa	95-102
8886580-9	1996	The concentration of glycine-extended gastrin was too low for chromatographic analysis.	Glycine	21-28	gastrin	Sus scrofa	38-45
8204590-0	1994	Replacement of the proximal ligand of sperm whale myoglobin with free imidazole in the mutant His-93--&gt;Gly.	Glycine	106-109	myoglobin	Physeter catodon	50-59
11814344-0	2002	A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine.	Glycine	9-16	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	76-81
8625867-2	1996	Peptides KS1-KS2 and KS2-KS1 represented sequences from the two viruses in both possible orders, separated by two glycine residues as spacers.	Glycine	114-121	zinc finger protein 382	Homo sapiens	9-12
11814344-7	2002	Similar point mutations at glycine 184 resulted in poor targeting of hENT1 to the plasma membrane and little or no detectable functional activity.	Glycine	27-34	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	69-74
11814344-9	2002	Based on these data, we conclude that when hENT1 is expressed in yeast, glycine 179 is critical not only to the ability of hENT1 to transport uridine but also as a determinant of hENT1 sensitivity to NBMPR.	Glycine	72-79	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	43-48
11834130-4	2002	Coupling of SpA to NHS-activated glycine-Sephadex appeared to be complete (immobilization capacity, approximately 300 microg of protein/ml of packed gel) when incubation was carried out at pH 4.0, in buffer of low ionic strength.	Glycine	33-40	surfactant protein A1	Homo sapiens	12-15
9079375-9	1996	CONCLUSIONS: The presence of a beta-turn in the Met-Ser-Gly-Arg sequence is strikingly similar to the behavior seen for the corresponding principal neutralizing determinant sequence from gp120 of HIV-1 and argues, in the absence of information of the three-dimensional structure of the intact proteins, for a similarity in the structure of this region that could be exploited in the design of synthetic peptide vaccines generally effective against HIV infections.	Glycine	56-59	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	187-192
11841571-10	2002	We here demonstrate for the first time the participation of CaM, CaMKII and the actin cytoskeleton in the regulation of Gly transport in glia.	Glycine	120-123	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	65-71
8789606-2	1995	Since it had previously been demonstrated that the enzyme can inactivate enkephalins and dynorphins in vitro by removing the N-terminal Tyr-Gly-Gly peptide, we wanted to see whether TPP II could be involved in this process also in vivo.	Glycine	140-143	tripeptidyl peptidase 2	Rattus norvegicus	182-188
8028417-10	1994	A mutation was identified in exon 3 (substitution of guanine with thymine) conditioning the substitution of the normal glycine amino acid by valine (HGPRT Madrid) on molecular study.	Glycine	119-137	hypoxanthine phosphoribosyltransferase 1	Homo sapiens	149-154
8789606-2	1995	Since it had previously been demonstrated that the enzyme can inactivate enkephalins and dynorphins in vitro by removing the N-terminal Tyr-Gly-Gly peptide, we wanted to see whether TPP II could be involved in this process also in vivo.	Glycine	144-147	tripeptidyl peptidase 2	Rattus norvegicus	182-188
12469900-7	2002	Furthermore, the Arg-Gly-Asp-Ser(RGDS)-peptide effectively inhibited collagen-triggered aggregation and CL, and the subsequent enhancement of the fMet-Leu-Phe-induced responses.	Glycine	21-24	ral guanine nucleotide dissociation stimulator	Homo sapiens	33-37
8749235-3	1995	MS-7 mAb recognized DPP IV (110 kDa) and its 60 kDa fragment, starting at the 281st residue corresponding to the extracellular one comprising the active-site sequence Gly-X-Ser631-X-Gly of DPP IV.	Glycine	167-170	dipeptidylpeptidase 4	Rattus norvegicus	20-26
8749235-3	1995	MS-7 mAb recognized DPP IV (110 kDa) and its 60 kDa fragment, starting at the 281st residue corresponding to the extracellular one comprising the active-site sequence Gly-X-Ser631-X-Gly of DPP IV.	Glycine	167-170	dipeptidylpeptidase 4	Rattus norvegicus	189-195
7517889-1	1994	(2S,1"R,2"R,3"R)-2-(2,3-Dicarboxycyclopropyl)glycine (DCG-IV), a potent agonist of subtypes 2 and 3 of metabotropic glutamate receptors (mGluR2 or 3), protected cultured cortical neurons against excitotoxicity induced either by a brief exposure to N-methyl-D-aspartate (NMDA) or a prolonged exposure to kainate.	Glycine	45-52	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	137-143
8028175-6	1994	I also describe our new protein engineering technique for creation of artificial cell adhesive proteins by grafting the Arg-Gly-Asp Ser (RGDS) cell recognition signal, which was identified first in fibronectin and later in various plasma and extracellular matrix proteins.	Glycine	124-127	ral guanine nucleotide dissociation stimulator	Homo sapiens	137-141
8749235-3	1995	MS-7 mAb recognized DPP IV (110 kDa) and its 60 kDa fragment, starting at the 281st residue corresponding to the extracellular one comprising the active-site sequence Gly-X-Ser631-X-Gly of DPP IV.	Glycine	182-185	dipeptidylpeptidase 4	Rattus norvegicus	20-26
11710891-6	2001	RESULTS: A G-to-C nucleotide change resulting in a glycine-alanine amino acid substitution at codon 206 (Gly206Ala) in exon 7 of presenilin 1 was observed in 23 individuals from 8 (42%) of the 19 families.	Glycine	51-58	presenilin 1	Homo sapiens	129-141
8749235-3	1995	MS-7 mAb recognized DPP IV (110 kDa) and its 60 kDa fragment, starting at the 281st residue corresponding to the extracellular one comprising the active-site sequence Gly-X-Ser631-X-Gly of DPP IV.	Glycine	182-185	dipeptidylpeptidase 4	Rattus norvegicus	189-195
7476914-5	1995	Glycine had an approximately 10-fold higher affinity (p &lt; 0.0001) for NR2B- than for NR2A-containing receptors (mKd = 0.057 and 0.53 microM, respectively).	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	73-77
7554111-0	1995	Osteopontin and beta 3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro.	Glycine	113-116	secreted phosphoprotein 1	Rattus norvegicus	0-11
8199873-3	1994	This suggests that TRH is mainly present in inhibitory interneurons which release GABA but not glycine, and provides further evidence that there are functional differences between those GABAergic neurons in the superficial dorsal horn that contain glycine, and those that do not.	Glycine	95-102	thyrotropin releasing hormone	Rattus norvegicus	19-22
8199873-3	1994	This suggests that TRH is mainly present in inhibitory interneurons which release GABA but not glycine, and provides further evidence that there are functional differences between those GABAergic neurons in the superficial dorsal horn that contain glycine, and those that do not.	Glycine	248-255	thyrotropin releasing hormone	Rattus norvegicus	19-22
11720283-6	2001	A synthetic peptide containing nine sDMA-glycine dipeptides, but not asymmetrically modified or nonmodified peptides, specifically inhibited the interaction of D1, D3, B/B", LSm4, and UsnRNPs with SMN-Tudor.	Glycine	41-48	leiomodin 1	Homo sapiens	160-172
7906695-7	1994	The data provide conclusive evidence that alterations at Gly 309 and Ser 376 are the genetic basis for CN-I in these families.	Glycine	57-60	5'-nucleotidase, cytosolic IA	Homo sapiens	103-107
7664666-2	1995	Rat pro-TRH contains five copies of the TRH progenitor sequence (Gln-His-Pro-Gly) and seven other cryptic peptides.	Glycine	77-80	thyrotropin releasing hormone	Rattus norvegicus	4-11
11395484-4	2001	Wild-type alpha1(P250) channels were nondesensitizing with an EC(50) for glycine of 8 microm, whereas bulky hydrophobic side chains of the channel variants alpha1(P250V/I/L/F) showed rapid desensitization (tau(desens), 50-250 ms) and EC(50) values of 400-1800 microm.	Glycine	73-80	TATA-box binding protein associated factor 1	Homo sapiens	0-21
8286753-9	1994	Substitution of Gly, Glu, or Met at position 104 also results in increased cleavage of the TfR and suggests that elimination of the O-linked carbohydrate at position 104 enhances the susceptibility of TfR to cleavage and may mimic a naturally occurring process previously described as being related to erythropoiesis.	Glycine	16-19	transferrin receptor	Homo sapiens	91-94
8286753-9	1994	Substitution of Gly, Glu, or Met at position 104 also results in increased cleavage of the TfR and suggests that elimination of the O-linked carbohydrate at position 104 enhances the susceptibility of TfR to cleavage and may mimic a naturally occurring process previously described as being related to erythropoiesis.	Glycine	16-19	transferrin receptor	Homo sapiens	201-204
11459447-6	2001	We also report the gram-scale syntheses of two other serine-containing peptides, ClAc-betaAla-Ser-Gly-OH and ClAc-Ser-Gly-OH, and three histidine-containing peptides, ClAc-Gly-His-Gly-OH, ClAc-betaAla-His-Gly-OH, and ClAc-His-Gly-OH.	Glycine	98-101	collagen type XXV alpha 1 chain	Homo sapiens	81-85
11406342-4	2001	The enhancement resulted from an increase in the affinity of glycine for NMDA receptors by GBP.	Glycine	61-68	transmembrane protein 132A	Rattus norvegicus	91-94
11455786-9	2001	Considering the different yields, 30% and 10%, respectively, of the LMW and the HMW fractions, the total amount of the LMW fraction present in the glucose-glycine mixture is more active in modulating these enzyme activities than that of the HMW fraction.	Glycine	155-162	cilia and flagella associated protein 97	Homo sapiens	80-83
8280139-7	1993	These three mutations result in changes of glycine to arginine and of tyrosine to aspartic acid at amino acid positions 71 and 486 of the UGT1A protein, and of leucine to proline and of tyrosine to aspartic acid at amino acid positions 132 and 487 of the UGT1D protein, respectively.	Glycine	43-50	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	138-143
11389857-2	2001	SMN binds the arginine- and glycine-rich (RG) domains of the snRNP proteins SmD1 and SmD3.	Glycine	28-35	survival of motor neuron 1, telomeric	Homo sapiens	0-3
7925478-3	1993	An increased rate of actin polymerization was found in "aggregating" conditions as compared to "activating" conditions, the latter achieved by either absence of stirring or stirring in the presence of the tetrapeptide Arg-Gly-Asp-Ser (RGDS).	Glycine	222-225	ral guanine nucleotide dissociation stimulator	Homo sapiens	235-239
11389857-2	2001	SMN binds the arginine- and glycine-rich (RG) domains of the snRNP proteins SmD1 and SmD3.	Glycine	28-35	small nuclear ribonucleoprotein D3 polypeptide	Homo sapiens	85-89
11309496-1	2001	Serine racemase is a brain-enriched enzyme that synthesizes d-serine, an endogenous modulator of the glycine site of N-methyl-d-aspartate (NMDA) receptors.	Glycine	101-108	serine racemase	Homo sapiens	0-15
8144352-0	1993	Hb Howick [beta 37(C3)Trp--&gt;Gly]: a new high oxygen affinity variant of the alpha 1 beta 2 contact.	Glycine	31-34	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	87-93
8144352-7	1993	The beta 37 residue is an alpha 1 beta 2 contact site and the substitution of the tryptophan for a glycine would be expected to result in a destabilization of the deoxy-hemoglobin form because of the reduced number of hydrogen bonds, salt bridges and van der Waal contacts between the alpha 1 and beta 2 chains.	Glycine	99-106	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	34-40
11301188-7	2001	Determination of cytokine mRNA in the course of Fas-mediated apoptosis in the presence of Tf or Tf-Gly showed upregulation of mRNA for Fas ligand and TNF-alpha in CD56(+) and downregulation of these transcripts along with upregulation of mRNA for interleukin-10 in CD3(+) marrow cells.	Glycine	99-102	CD3 antigen, epsilon polypeptide	Mus musculus	265-268
8307570-4	1993	The first 7 exons encode the N-terminal domain of EWS, which consists of a repeated degenerated polypeptide of 7 to 12 residues rich in tyrosine, serine, threonine, glycine, and glutamine.	Glycine	165-172	EWS RNA binding protein 1	Homo sapiens	50-53
11301188-8	2001	Under these conditions, a distinct increase in Fas-associated phosphatase-1 message was observed in CD3(+) cells that were protected by Tf or Tf-Gly against apoptosis.	Glycine	145-148	CD3 antigen, epsilon polypeptide	Mus musculus	100-103
11273710-4	2001	Sequence alignment of a large number of SH3 domains reveals that the drkN SH3 domain has a threonine (T22) at a position corresponding to an otherwise highly conserved glycine residue in the diverging beta-turn connecting the beta3 and beta4 strands.	Glycine	168-175	beta-Tubulin at 60D	Drosophila melanogaster	226-241
8309954-1	1993	The effects of endogenous opioid peptides are limited by proteolytic enzymes such as endopeptidase 24.11 ("enkephalinase"), which cleaves the Gly-Phe bonds in Met- and Leu-enkephalin.	Glycine	142-145	membrane metallo endopeptidase	Mus musculus	107-121
8260192-13	1993	This could be due to a rapid conjugation of butyryl-CoA with glycine by an increased activity of glycine N-acyltransferase.	Glycine	61-68	glycine-N-acyltransferase	Mus musculus	97-122
11237737-4	2001	Single point mutation of four cysteine residues in extracellular loops to glycine (C35G, C267G, C273G, and C275G) resulted in a complete loss of binding for [125I]-NDP-MSH.	Glycine	74-81	norrin cystine knot growth factor NDP	Homo sapiens	164-167
11258897-6	2001	[D-Ala(2)]GLP-1 and [Gly(2)]GLP-1 showed normal or relatively lower receptor binding and cAMP activation but exerted markedly enhanced abilities to reduce the glycemic response to an OGTT in vivo.	Glycine	21-24	glucagon	Mus musculus	28-33
8244629-7	1993	Hydrophobic substitutions Leu and D-Trp at positions 11 (Lys) and 12 (Gly), respectively, in PTHrP-(7-34)NH2 resulted in increased potency, but the derivatives were not significantly more helical than the unsubstituted peptide in the presence of surfactants.	Glycine	70-73	parathyroid hormone like hormone	Homo sapiens	93-98
11170182-5	2001	Pretreatment with Gly-Arg-Gly-Asp-Ser peptide inhibited the SSC increasing action of 12-o-tetradecanoyl-phorbol-13-acetate (TPA, 0.5 microM) plus fibronectin, but not that of TPA plus laminin.	Glycine	18-21	fibronectin 1 S homeolog	Xenopus laevis	146-157
8284261-1	1993	We examined the effects of captopril (an angiotensin-converting enzyme inhibitor) and phosphoramidon (a selective enkephalinase inhibitor) on Tyr-Gly-Gly production during Met-enkephalin hydrolysis in plasma samples taken from individual outbred Swiss-Webster and inbred C57BL/6J and DBA/2J mice.	Glycine	146-149	pro-opiomelanocortin-alpha	Mus musculus	172-186
8284261-1	1993	We examined the effects of captopril (an angiotensin-converting enzyme inhibitor) and phosphoramidon (a selective enkephalinase inhibitor) on Tyr-Gly-Gly production during Met-enkephalin hydrolysis in plasma samples taken from individual outbred Swiss-Webster and inbred C57BL/6J and DBA/2J mice.	Glycine	150-153	pro-opiomelanocortin-alpha	Mus musculus	172-186
8344522-3	1993	The dnaK coding sequence displays extreme codon bias and shows a strong preference for CGY and GGY, for Arg and Gly codons, respectively.	Glycine	112-115	dnaK	Streptomyces coelicolor A3(2)	4-8
11071891-2	2001	The deduced amino acid sequence of CORS26 consists of 246 amino acids with a secretory signal peptide and contains a collagenous region (Gly-X-Y repeats) at the NH(2) terminus and a complement factor C1q globular domain at the COOH terminus.	Glycine	137-140	C1q and tumor necrosis factor related protein 3	Mus musculus	35-41
8325838-3	1993	We demonstrate using flow cytometric methods a central role for the beta 3 integrin glycoprotein (GP) IIb-IIIa complex and its ligand tetrapeptide Arg-Gly-Asp-Ser (RGDS) binding site in platelet vesiculation.	Glycine	151-154	ral guanine nucleotide dissociation stimulator	Homo sapiens	164-168
8329391-1	1993	Protein disulfide-isomerase (PDI) contains two thioredoxin-like domains with the active-site sequence: Cys-Gly-His-Cys.	Glycine	107-110	prolyl 4-hydroxylase subunit beta	Bos taurus	0-27
11294565-7	2001	Genetic complexity at the TAP2 locus was further enhanced by two out of five synonymous SNPs (S-SNPs), especially the GGT386GGG (Gly) that had similar heterozygosity rates in Caucasians (28.9%), Rwandans (33.3%), and Zambians (33.3%).	Glycine	129-132	transporter 2, ATP binding cassette subfamily B member	Homo sapiens	26-30
11306065-1	2001	Class IV alcohol dehydrogenase shows a deletion at position 117 with respect to class I enzymes, which typically have a Gly residue.	Glycine	120-123	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	Homo sapiens	0-30
8329391-1	1993	Protein disulfide-isomerase (PDI) contains two thioredoxin-like domains with the active-site sequence: Cys-Gly-His-Cys.	Glycine	107-110	prolyl 4-hydroxylase subunit beta	Bos taurus	29-32
8329391-1	1993	Protein disulfide-isomerase (PDI) contains two thioredoxin-like domains with the active-site sequence: Cys-Gly-His-Cys.	Glycine	107-110	thioredoxin	Bos taurus	47-58
12083956-10	2001	The coregulatory proteins ARA70 and ARA160 differentially affected the activity of the mutated AR Glu(231)--&gt;Gly, which was discovered in a mouse authochthonous prostate tumor.	Glycine	112-115	nuclear receptor coactivator 4	Mus musculus	26-31
8019886-7	1993	DQA1*01 group of alleles (DQA1*0101, 0102 or 0103 allele) encode DQ alpha chains sharing long polymorphic sequence including non-charged glycine and positively charged arginine residues at positions 55 and 64, respectively.	Glycine	137-144	major histocompatibility complex, class II, DQ alpha 1	Homo sapiens	0-4
8019886-7	1993	DQA1*01 group of alleles (DQA1*0101, 0102 or 0103 allele) encode DQ alpha chains sharing long polymorphic sequence including non-charged glycine and positively charged arginine residues at positions 55 and 64, respectively.	Glycine	137-144	major histocompatibility complex, class II, DQ alpha 1	Homo sapiens	26-30
7476899-3	1995	Ethanol dose-response analysis revealed enhanced inhibitory efficacy of ethanol in the presence of subsaturating glycine concentrations at the NR1/NR2A, NR1/NR2C, and NR1/NR2D receptors.	Glycine	113-120	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	147-151
7476899-3	1995	Ethanol dose-response analysis revealed enhanced inhibitory efficacy of ethanol in the presence of subsaturating glycine concentrations at the NR1/NR2A, NR1/NR2C, and NR1/NR2D receptors.	Glycine	113-120	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	171-175
11114935-3	2001	We have used site-directed mutagenesis to construct derivatives of UmuD and UmuD" with glycines in place of leucine-101 and arginine-102.	Glycine	87-95	UmuD	Escherichia coli	67-71
7673195-4	1995	The hnRNP A1, A2/B1, and D0 proteins, all possess common features of the 2xRBD-Gly structure and binding specificity toward RNA.	Glycine	79-82	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	4-12
11114935-3	2001	We have used site-directed mutagenesis to construct derivatives of UmuD and UmuD" with glycines in place of leucine-101 and arginine-102.	Glycine	87-95	UmuD	Escherichia coli	76-80
8690729-0	1995	Significance of the highly conserved Gly-4 residue in human cystatin A.	Glycine	37-40	cystatin A	Homo sapiens	60-70
8481514-4	1993	Analysis of the genes for two other components of the platelet GPIb:IX complex, namely GPIb beta and GPIX, showed two different missense mutations in the coding region of the GPIX gene: an A-->G transition in codon 21 results in conversion of an aspartic acid to glycine and an A-->G change in codon 45 converts an asparagine residue to serine.	Glycine	263-270	glycoprotein IX platelet	Homo sapiens	101-105
8481514-4	1993	Analysis of the genes for two other components of the platelet GPIb:IX complex, namely GPIb beta and GPIX, showed two different missense mutations in the coding region of the GPIX gene: an A-->G transition in codon 21 results in conversion of an aspartic acid to glycine and an A-->G change in codon 45 converts an asparagine residue to serine.	Glycine	263-270	glycoprotein IX platelet	Homo sapiens	175-179
11145986-4	2001	The NMDA (100 microM)-evoked release of [(3)H]NA and [(3)H]DA was similar and concentration-dependently enhanced by glycine or D-serine (0.1-1 microM); in contrast, the HIV-1 envelope protein gp120 potently (30-100 pM) enhanced the NMDA-evoked release of [(3)H]NA, but not that of [(3)H]DA.	Glycine	116-123	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	192-197
8495193-11	1993	We measured the time course of activation and binding of glycine to C4A and C4B.	Glycine	57-64	complement C4B (Chido blood group)	Homo sapiens	76-79
7543279-2	1995	We have used the protein Rop to test the feasibility of using short glycine-rich linkers to reconnect the alpha-helices within a four-helix-bundle protein.	Glycine	68-75	opsin 1, long wave sensitive	Homo sapiens	25-28
11056469-2	2000	In the case of glycine and GABA(A) receptors, gephyrin has been shown to serve this function.	Glycine	15-22	gephyrin	Mus musculus	46-54
7550112-1	1995	A nicked form of human chorionic gonadotropin (nicked hCG), in which only one peptide bond between residues 47 and 48 (-Gly-Val-) of beta-subunit is cleaved, has been found in the urine and blood of pregnant women.	Glycine	120-123	chorionic gonadotropin subunit beta 5	Homo sapiens	54-57
8450241-8	1993	Residual contaminating levels of SpA in affinity purified MAbs were lowest with a low salt (NaCl, 150 mM) glycine (1 M) adsorption/washing buffer.	Glycine	106-113	surfactant protein A1	Homo sapiens	33-36
11056469-3	2000	However, it is unknown whether gephyrin is involved in the clustering of all glycine and GABA(A) receptors or whether it interacts only with specific isoforms.	Glycine	77-84	gephyrin	Mus musculus	31-39
8451200-11	1993	Multiple protein isoforms for the hnRNP A2 gene are predicted that differ by the insertion of short peptide sequences in the glycine-rich domain.	Glycine	125-132	heterogeneous nuclear ribonucleoprotein A2/B1 S homeolog	Xenopus laevis	34-42
11100728-3	2000	The predicted MOD-1 protein is similar to members of the nicotinic acetylcholine receptor family of ligand-gated ion channels, in particular to GABA (gamma-aminobutyric acid)- and glycine-gated chloride channels.	Glycine	180-187	Uncharacterized protein	Caenorhabditis elegans	14-19
7595597-3	1995	In the immature slice, glycine potentiated GLU elicited AChE release in the presence of strychnine, suggesting N-methyl-D-aspartate (NMDA) receptor involvement.	Glycine	23-30	acetylcholinesterase	Mus musculus	56-60
11063571-0	2000	Removal of the four C-terminal glycine-rich repeats enhances the thermostability and substrate binding affinity of barley beta-amylase.	Glycine	31-38	1,4-alpha-D-glucan maltohydrolase	Hordeum vulgare	122-134
7542253-7	1995	GRGDS (gly-arg-gly-asp-ser) peptides inhibited cell adhesion to intact GST-OPN, as well as to fibronectin and vitronectin.	Glycine	7-10	secreted phosphoprotein 1	Mus musculus	75-78
7542253-7	1995	GRGDS (gly-arg-gly-asp-ser) peptides inhibited cell adhesion to intact GST-OPN, as well as to fibronectin and vitronectin.	Glycine	15-18	secreted phosphoprotein 1	Mus musculus	75-78
8381833-1	1993	Microvariation within the DR1 Ag family has created two DR molecules which differ only at beta-chain residues 85 (Val/Ala) and 86 (Gly/Val).	Glycine	131-134	down-regulator of transcription 1	Homo sapiens	26-29
11063571-7	2000	The possible reasons for the increased thermostability and substrate binding affinity, due to the removal of the four C-terminal glycine-rich repeats, are discussed in terms of the three-dimensional structure of beta-amylase.	Glycine	129-136	1,4-alpha-D-glucan maltohydrolase	Hordeum vulgare	212-224
1332063-1	1992	Dihydrolipoamide dehydrogenase (E3; EC 1.8.1.4) is the common component of the three mammalian alpha-ketoacid dehydrogenase complexes and the glycine cleavage system.	Glycine	142-149	dihydrolipoamide dehydrogenase	Homo sapiens	0-30
7773293-3	1995	We report the association of a single heterozygous Gly to Ser missense mutation in the glucagon receptor gene with late-onset NIDDM.	Glycine	51-54	glucagon receptor	Homo sapiens	87-104
11395134-1	2000	The encephalitogenic epitope P81-100 from mouse myelin basic protein was used to generate two simplified derivatives with glycine substitutions in alternating positions which were tested for their biological activity in a murine model of multiple sclerosis, experimental autoimmune encephalomyelitis.	Glycine	122-129	myelin basic protein	Mus musculus	48-68
7871161-1	1995	Paramagnetic molecular centers produced by gamma irradiation at 77 K and at 293 K in Alx(OH)y, when precipitated with glycine or serine, were studied by ESR spectroscopy.	Glycine	118-125	hematopoietic SH2 domain containing	Homo sapiens	85-88
11080300-1	2000	We have previously shown that in Nicotiana sylvestris cytoplasmic male-sterile (CMS) mutants where the mtDNA lacks the nad7 gene coding for a subunit of respiratory Complex I (NADH:ubiquinone oxidoreductase, EC 1.6.5.3), glycine (Gly) oxidation was lower than in the wild type and insensitive to rotenone, suggesting Complex I dysfunction.	Glycine	221-228	NADH dehydrogenase subunit 7	Nicotiana sylvestris	119-123
7761629-7	1995	The amino acid sequence of sturgeon GnRH is pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2.	Glycine	65-68	gonadotropin releasing hormone 1	Homo sapiens	36-40
1426234-1	1992	It is shown that the second cholera toxin, Zot, ORF3 product of Pseudomonas plasmid pKB740, and ORF424 product of bacteriophage Pf1 are a group of closely related proteins containing a modified version of the purine NTP-binding motif, with a drastic substitution of tyrosine for a conserved glycine.	Glycine	291-298	putative assembly protein	Pseudomonas virus Pf1	96-102
11080300-1	2000	We have previously shown that in Nicotiana sylvestris cytoplasmic male-sterile (CMS) mutants where the mtDNA lacks the nad7 gene coding for a subunit of respiratory Complex I (NADH:ubiquinone oxidoreductase, EC 1.6.5.3), glycine (Gly) oxidation was lower than in the wild type and insensitive to rotenone, suggesting Complex I dysfunction.	Glycine	230-233	NADH dehydrogenase subunit 7	Nicotiana sylvestris	119-123
7862666-1	1995	Glutathione (GSH) synthetase [gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming), EC 6.3.2.3], an enzyme present in almost all cells, catalyzes the ATP-dependent synthesis of GSH from gamma-L-glutamyl-L-cysteine and glycine.	Glycine	58-65	glutathione synthetase	Rattus norvegicus	0-28
11098404-2	2000	We chemically synthesized a Tat protein (86 residues) with its six glycines C alpha labelled with 13C.	Glycine	67-75	tyrosine aminotransferase	Homo sapiens	28-31
7535732-3	1994	Recently, we described a leprechaun patient having an Arg for Gly substitution in one allele of the insulin receptor whereas the other allele has the normal sequence.	Glycine	62-65	insulin receptor	Homo sapiens	100-116
1400325-4	1992	Cytoskeletal association and platelet aggregation were inhibited by the peptide Arg-Gly-Asp-Ser (RGDS) (but not by Arg-Gly-Glu-Ser (RGES)), by 10E5 antibody against glycoprotein (Gp) IIb/IIIa, and by EGTA.	Glycine	84-87	ral guanine nucleotide dissociation stimulator	Homo sapiens	97-101
10999937-3	2000	In this report, a mutant hMR, in which the residue Ala-773 facing the C11 steroid position was replaced by a glycine (A773G), was assayed for its capacity to bind steroids, to interact with receptor coactivators, and to stimulate transcription.	Glycine	109-116	mannose receptor C-type 1	Homo sapiens	25-28
1520337-9	1992	A glycine, not found in purified indolicidin, is present at the carboxyl terminus of the deduced sequence and is very likely involved in post-translational peptide amidation.	Glycine	2-9	cathelicidin-4	Bos taurus	33-44
10861272-7	2000	RESULTS: Mice treated with GLP-2 or h[Gly(2)]GLP-2 for 10 days demonstrated significantly reduced intestinal conductance and fluxes of Na(+), Cr-EDTA, and HRP.	Glycine	38-41	glucagon-like peptide 2 receptor	Mus musculus	27-32
1643115-7	1992	(3) Arg-Gly-Asp-Ser (RGDS) peptide, a synthetic anti-adhesive peptide, inhibited aggregation of thrombin-activated platelets in a dose-dependent manner (100-200 microM).	Glycine	8-11	ral guanine nucleotide dissociation stimulator	Homo sapiens	21-25
1637938-8	1992	On the basis of putative cleavage sites on the SP-10 sequence, endoproteases that act at five different peptide bonds are predicted to cleave SP-10: these hydrolyze following arginine (a trypsin-like protease, possibly acrosin), and following serine, proline, glycine, and glutamic acid (previously undescribed intra-acrosomal protease specificities).	Glycine	260-267	acrosomal vesicle protein 1	Homo sapiens	142-147
7959024-2	1994	The major difference is that the chick sequence lacks a run of Gly residues present in mouse and human HoxB3.	Glycine	63-66	homeobox B3	Homo sapiens	103-108
7971977-3	1994	As for NR1(011) homomers, NR1(011)/NR2B receptors exhibited spermine potentiation by two mechanisms: by increasing glycine affinity and by increasing current through receptors with bound N-methyl-D-aspartate and glycine.	Glycine	115-122	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	26-29
7971977-3	1994	As for NR1(011) homomers, NR1(011)/NR2B receptors exhibited spermine potentiation by two mechanisms: by increasing glycine affinity and by increasing current through receptors with bound N-methyl-D-aspartate and glycine.	Glycine	212-219	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	26-29
7971977-4	1994	NR1(011)/NR2A receptors exhibited only the increase in glycine affinity, and NR1(011)/NR2C receptors exhibited neither.	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	0-3
7971977-5	1994	As for NR1(100) homomers, NR1(100)/NR2B and NR1(100)/NR2A receptors exhibited spermine potentiation only by increasing the glycine affinity.	Glycine	123-130	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	26-29
7971977-5	1994	As for NR1(100) homomers, NR1(100)/NR2B and NR1(100)/NR2A receptors exhibited spermine potentiation only by increasing the glycine affinity.	Glycine	123-130	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	26-29
10861272-7	2000	RESULTS: Mice treated with GLP-2 or h[Gly(2)]GLP-2 for 10 days demonstrated significantly reduced intestinal conductance and fluxes of Na(+), Cr-EDTA, and HRP.	Glycine	38-41	glucagon-like peptide 2 receptor	Mus musculus	45-50
1352429-0	1992	Dopamine DA1 receptor agonist, fenoldopam, reverses glycine-induced hyperfiltration in rats.	Glycine	52-59	RT1 class II, locus Da	Rattus norvegicus	9-12
1352429-2	1992	In the present study we have therefore investigated whether the DA1 agonist, fenoldopam, can prevent glycine-induced hyperfiltration.	Glycine	101-108	RT1 class II, locus Da	Rattus norvegicus	64-67
10747935-10	2000	Mutagenesis of residues N-terminal to Gly(170) impaired both GTP binding and TGase activity.	Glycine	38-41	transglutaminase 1	Homo sapiens	77-82
1352429-9	1992	Thus DA1 receptor activation can prevent glomerular hyperfiltration induced by glycine.	Glycine	79-86	RT1 class II, locus Da	Rattus norvegicus	5-8
7531403-4	1994	This high-affinity Mg2+ site has been shown to increase the binding of N-[1-(2-thienyl) cyclohexyl]piperidine within the ion channel, as well as the binding of competitive antagonist such as 3-(+/-)-carboxypiperazine-4-yl)-[1,2]-propyl-1-phosphonic acid and the receptor coactivator glycine.	Glycine	283-290	mucin 7, secreted	Homo sapiens	19-22
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	188-192
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	212-216
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	145-152	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	188-192
1501405-6	1992	PO4-depleted rPT, LDH release was diminished significantly by glycine treatment (31.0 +/- 0.9 vs. 15.5 +/- 1.6%, P less than 0.001) or acidosis (30.3 +/- 0.04 vs. 19.2 +/- 0.9%, P less than 0.01).	Glycine	62-69	magnesium transporter MRS2	Rattus norvegicus	13-16
10747901-2	2000	PAX6 has two DNA binding domains, a glycine-rich region that links the two DNA binding domains, and a transactivation domain.	Glycine	36-43	paired box 6	Homo sapiens	0-4
8062839-3	1994	The cDNA (GBP1) sequence predicts a protein product (Gbp1p) that includes two domains with extensive homology to RNA recognition motifs (RRMs) and a region rich in glycine, alanine and arginine.	Glycine	164-171	uncharacterized protein	Chlamydomonas reinhardtii	10-14
8062839-3	1994	The cDNA (GBP1) sequence predicts a protein product (Gbp1p) that includes two domains with extensive homology to RNA recognition motifs (RRMs) and a region rich in glycine, alanine and arginine.	Glycine	164-171	uncharacterized protein	Chlamydomonas reinhardtii	53-58
8052270-10	1994	These results suggest that cysteine 116 and glycine 615 are critical to the repair function of CXPD.	Glycine	44-51	general transcription and DNA repair factor IIH helicase subunit XPD	Cricetulus griseus	95-99
1375326-2	1992	A mutation of the amino-terminal site of myristylation (glycine 2), which prevents stable association of p56lck with the plasma membrane, completely abolished the ability of F505 p56lck to enhance TCR-induced tyrosine protein phosphorylation.	Glycine	56-63	lymphocyte protein tyrosine kinase	Mus musculus	105-111
10816435-5	2000	Glycine, L-asparagine and L-serine, as well as their D-enantiomers, were the strongest effectors and acted in a concentration-dependent manner; millimolar concentrations of most of these amino acids being sufficient to significantly increase ODC activity.	Glycine	0-7	ornithine decarboxylase 1	Homo sapiens	242-245
1375326-2	1992	A mutation of the amino-terminal site of myristylation (glycine 2), which prevents stable association of p56lck with the plasma membrane, completely abolished the ability of F505 p56lck to enhance TCR-induced tyrosine protein phosphorylation.	Glycine	56-63	lymphocyte protein tyrosine kinase	Mus musculus	179-185
1572651-8	1992	All of the PSGs except PSG1, PSG4, and PSG8 contained the arginine-glycine-aspartic acid sequence at position 93-95 corresponding to the complementarity determining region 3 of immunoglobulin.	Glycine	67-74	pregnancy specific beta-1-glycoprotein 8	Homo sapiens	39-43
7972490-2	1994	The cDNA library was made from poly(A)+ RNA from leaves challenged with mercuric chloride for 2 d. The two clones, pCh2 and pCh11, appear to encode class I chitinase isoforms with cysteine-rich domains (not found in pCh11 due to the incomplete sequence) and proline-/glycine-rich or proline-rich hinge domains, respectively.	Glycine	267-274	pCh2	Zea mays	115-119
8034703-2	1994	In order to establish whether a single enzyme in human liver was capable of conjugating bile acids with both glycine and taurine, a cDNA encoding human liver bile acid-CoA:amino acid N-acyltransferase (hBAT) has been isolated and characterized.	Glycine	109-116	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	158-200
10816435-11	2000	Supplemental glycine also augmented, reversibly, the half-life of ODC by almost 4-fold and simultaneously decreased the activity of putrescine-induced free antizyme.	Glycine	13-20	ornithine decarboxylase 1	Homo sapiens	66-69
8002930-5	1994	The overall composition of the deduced amino acid sequence matched that expected for a mucin protein core and is rich in serine, threonine, proline, glycine and alanine (approximately 51%).	Glycine	149-156	LOC100508689	Homo sapiens	87-92
10725561-4	2000	The main part of the deduced amino acid sequences of the 14.6 kD GRP1 and the larger GRP2 consists of glycine-rich repetitive elements essentially as found for GRPs in other plants.	Glycine	102-109	glycine-rich cell wall structural protein	Cicer arietinum	65-69
8190097-7	1994	Glycine-dependent stimulation was seen at NR1A/NR2A and NR1A/NR2B receptors and may therefore involve a second polyamine binding site distinct from that which produces glycine-independent stimulation.	Glycine	0-7	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	47-51
1624955-1	1992	Many adhesive proteins present in extracellular matrices and in blood contain the tetrapeptide sequence -Arg-Gly-Asp-Ser- (or RGDS) at their cell recognition site.	Glycine	109-112	ral guanine nucleotide dissociation stimulator	Homo sapiens	126-130
1560388-0	1992	Renin-angiotensin system inhibition reduces glycine-induced glomerular hyperfiltration in conscious rats.	Glycine	44-51	renin	Rattus norvegicus	0-5
10725561-4	2000	The main part of the deduced amino acid sequences of the 14.6 kD GRP1 and the larger GRP2 consists of glycine-rich repetitive elements essentially as found for GRPs in other plants.	Glycine	102-109	glycine-rich protein 2	Cicer arietinum	85-89
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	262-266
10780999-1	2000	The potency of two novel glycine site antagonists, GV150,526A and GV196,771A, was assessed by their ability to inhibit the binding of [(3)H]-MDL105,519 to cell homogenates prepared from mammalian cells transfected with either NR1-1a, NR1-2a, NR1-1a/NR2A, NR1-1a/NR2B, NR1-1a/NR2C or NR1-1a/NR2D NMDA receptor clones.	Glycine	25-32	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	275-279
7910017-2	1994	Here, we show that botulinum toxin type G cleaves rat synaptobrevin 2 between Ala81 and Ala82, a peptide bond that differs from those attacked by tetanus toxin and the botulinal toxins types B, D, and F. Synaptobrevin isoforms carrying a Gly in the P1 position are poor substrates.	Glycine	238-241	vesicle-associated membrane protein 2	Rattus norvegicus	54-69
10801967-6	2000	A 3-wk supplementation with zinc (30 mg/d as glycine-chelate) raised initially low plasma zinc values to above normal values and increased plasma activities of 5"-nucleotidase.	Glycine	45-52	5'-nucleotidase ecto	Homo sapiens	160-175
1552943-6	1992	Cloning and sequencing of PMP-22 complementary DNAs from inbred Tr mice reveals a point mutation that substitutes an aspartic acid residue for a glycine in a putative membrane-associated domain of the PMP-22 protein.	Glycine	145-152	peripheral myelin protein 22	Mus musculus	26-32
1552943-6	1992	Cloning and sequencing of PMP-22 complementary DNAs from inbred Tr mice reveals a point mutation that substitutes an aspartic acid residue for a glycine in a putative membrane-associated domain of the PMP-22 protein.	Glycine	145-152	peripheral myelin protein 22	Mus musculus	201-207
1421205-0	1992	Effects of dexamethasone on TRH and TRH precursor peptide (Lys-Arg-Gln-His-Pro-Gly-Arg-Arg) levels in various rat organs.	Glycine	79-82	thyrotropin releasing hormone	Rattus norvegicus	36-39
8163535-5	1994	The extracellular domain of the syndecan-1 core protein contains five Ser-Gly sites, three clustered near its N terminus and two adjacent to the transmembrane domain near its C terminus.	Glycine	74-77	syndecan 1	Mus musculus	32-42
10753918-7	2000	By contrast, truncation at Gly(359) created a dominant-negative mutant that inhibited ligand-induced cell death and activation of NF-kappaB p50/p65 heterodimers.	Glycine	27-30	RELA proto-oncogene, NF-kB subunit	Homo sapiens	144-147
8131848-3	1994	In the present report we describe a sequence polymorphism of the C8B gene (codon 63: AGA--&gt;GGA) and demonstrate that the resulting amino acid substitution (Arg--&gt;Gly) consistently differentiates between the two common charge variants of the C8 beta chain; the C8B B allotype is characterized by an Arg and the C8B A allotype by a Gly residue in position 63 of the C8 beta polypeptide chain.	Glycine	168-171	complement C8 beta chain	Homo sapiens	65-68
10744740-5	2000	The primary mutations in atp1-1 and atp1-2 were identified as Thr(383) --&gt; Ile and Gly(291) --&gt; Asp, respectively.	Glycine	86-89	ATP synthase complex assembly protein ATP12	Saccharomyces cerevisiae S288C	36-42
8131848-3	1994	In the present report we describe a sequence polymorphism of the C8B gene (codon 63: AGA--&gt;GGA) and demonstrate that the resulting amino acid substitution (Arg--&gt;Gly) consistently differentiates between the two common charge variants of the C8 beta chain; the C8B B allotype is characterized by an Arg and the C8B A allotype by a Gly residue in position 63 of the C8 beta polypeptide chain.	Glycine	168-171	complement C8 beta chain	Homo sapiens	247-254
8131848-3	1994	In the present report we describe a sequence polymorphism of the C8B gene (codon 63: AGA--&gt;GGA) and demonstrate that the resulting amino acid substitution (Arg--&gt;Gly) consistently differentiates between the two common charge variants of the C8 beta chain; the C8B B allotype is characterized by an Arg and the C8B A allotype by a Gly residue in position 63 of the C8 beta polypeptide chain.	Glycine	168-171	complement C8 beta chain	Homo sapiens	266-269
8131848-3	1994	In the present report we describe a sequence polymorphism of the C8B gene (codon 63: AGA--&gt;GGA) and demonstrate that the resulting amino acid substitution (Arg--&gt;Gly) consistently differentiates between the two common charge variants of the C8 beta chain; the C8B B allotype is characterized by an Arg and the C8B A allotype by a Gly residue in position 63 of the C8 beta polypeptide chain.	Glycine	168-171	complement C8 beta chain	Homo sapiens	266-269
8131848-3	1994	In the present report we describe a sequence polymorphism of the C8B gene (codon 63: AGA--&gt;GGA) and demonstrate that the resulting amino acid substitution (Arg--&gt;Gly) consistently differentiates between the two common charge variants of the C8 beta chain; the C8B B allotype is characterized by an Arg and the C8B A allotype by a Gly residue in position 63 of the C8 beta polypeptide chain.	Glycine	168-171	complement C8 beta chain	Homo sapiens	370-377
8131848-3	1994	In the present report we describe a sequence polymorphism of the C8B gene (codon 63: AGA--&gt;GGA) and demonstrate that the resulting amino acid substitution (Arg--&gt;Gly) consistently differentiates between the two common charge variants of the C8 beta chain; the C8B B allotype is characterized by an Arg and the C8B A allotype by a Gly residue in position 63 of the C8 beta polypeptide chain.	Glycine	336-339	complement C8 beta chain	Homo sapiens	65-68
1421205-1	1992	The effect of an acute dexamethasone administration on thyrotropin-releasing hormone (TRH) and TRH precursor peptide (Lys-Arg-Gln-His-Pro-Gly-Arg-Arg) (p-8) levels in various rat organs has been studied.	Glycine	138-141	thyrotropin releasing hormone	Rattus norvegicus	95-98
1618659-3	1992	Substitution of alanine and valine for valine and glycine residues at positions 85 and 86 of the DR1 beta chain resulted in deficient T-cell stimulation as demonstrated by the requirement for higher concentrations of antigen to induce maximal levels of T-cell proliferation, induction of lower levels of proliferation at optimal antigen concentrations, and slower kinetics of formation of stimulatory peptide-DR1 complexes.	Glycine	50-57	down-regulator of transcription 1	Homo sapiens	97-100
10784431-1	2000	We have studied the influence of Gly-Ala-Arg peptide at the N-terminus and the oligosaccharide at Asn184 on the clearance of tissue plasminogen activator (t-PA).	Glycine	33-36	plasminogen activator, tissue	Mus musculus	125-159
1531588-6	1992	During digestion of fibrinogen at low plasmin concentration, up to 65% of the FpA was cleaved just subsequent to the progressive release of B beta-(1-42)-peptide, and the Arg-16-Gly-17 bond of the A alpha-chain became relatively stable towards plasmin action when present in fragment E (and possibly fragment Y).	Glycine	178-181	plasminogen	Homo sapiens	38-45
7513083-1	1994	We have characterized the expression of two members of a class of Arabidopsis thaliana glycine-rich, putative RNA-binding proteins that we denote Ccr1 and Ccr2.	Glycine	87-94	CRINKLY4 related 2	Arabidopsis thaliana	155-159
8278385-0	1994	Ala--&gt;Gly mutation in the putative catalytic loop confers temperature sensitivity on Ros, insulin receptor, and insulin-like growth factor I receptor protein-tyrosine kinases.	Glycine	9-12	insulin receptor	Homo sapiens	93-152
10733677-5	2000	Because the EDA segment enhances the integrin binding sequence Arg, Gly, Asp (RGD), which, when present, has been shown to be critical in integrin-extracellular matrix signaling, we were particularly interested in determining whether or not EDA-containing Fn (EDA+Fn) represented the aberrantly expressed Fn in psoriasis.	Glycine	68-71	ectodysplasin A	Homo sapiens	12-15
8263031-10	1994	Adding the synthetic peptide, arg-gly-asp-ser (RGDS) to the medium, blocked migration on fibronectin-coated implants but had no effect on implants coated with type IV, suggesting that migration on type IV involves different cell surface receptors than those mediating migration over fibronectin.	Glycine	34-37	ral guanine nucleotide dissociation stimulator	Homo sapiens	47-51
8262937-2	1993	Single turnover and equilibrium binding measurements on the interaction of Gly-12 and Pro-12 Ras.GTP with the catalytic domains of the GTPase-activating proteins, p120-GAP and neurofibromin, have been made utilizing fluorescent 2"(3")O-(N-methylanthraniloyl)-nucleotides.	Glycine	75-78	RAS p21 protein activator 1	Homo sapiens	163-171
8262937-5	1993	Both p120-GAP and neurofibromin increased the rate constant of the GTP hydrolysis step of Pro-12 Ras, but the maximal activation at 30 degrees C was 120-fold and 560-fold, as compared with 70,000- and 52,000-fold, with Gly-12 Ras.	Glycine	219-222	RAS p21 protein activator 1	Homo sapiens	5-13
8262937-6	1993	The affinity with which p120-GAP and neurofibromin binds to either Gly-12 or Pro-12 Ras protein was decreased dramatically by increasing ionic strength caused by addition of NaCl.	Glycine	67-70	RAS p21 protein activator 1	Homo sapiens	24-32
1730390-1	1992	Sequence analysis of cDNA clones encoding fibronectin (FN) from Xenopus laevis reveals extensive amino acid identities with other vertebrate FNs, including the presence of the Arg-Gly-Asp (RGD) cell attachment site in type III-10 and of a second, cell-binding site (EILDV) in the alternative spliced V region of the protein.	Glycine	180-183	fibronectin 1 S homeolog	Xenopus laevis	42-53
1730390-1	1992	Sequence analysis of cDNA clones encoding fibronectin (FN) from Xenopus laevis reveals extensive amino acid identities with other vertebrate FNs, including the presence of the Arg-Gly-Asp (RGD) cell attachment site in type III-10 and of a second, cell-binding site (EILDV) in the alternative spliced V region of the protein.	Glycine	180-183	fibronectin 1 S homeolog	Xenopus laevis	55-57
10817395-2	2000	The cytosolic bile acid-CoA:amino acid N-acyltransferase catalyse the conjugation of the CoA-activated bile acids with taurine or glycine prior to secretion into bile.	Glycine	130-137	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	14-56
1736943-4	1992	The peptides of the first family starting from the C-terminal Gly-532 of gp160 (BRU isolate) were assembled in a stepwise manner to N-terminus of gp41(Ala-517).	Glycine	62-65	glutamyl aminopeptidase	Homo sapiens	73-78
8304052-1	1993	The bone sialoprotein osteopontin (OPN) promotes cell attachment and spreading through its RGD (Arg-Gly-Asp) sequence.	Glycine	100-103	secreted phosphoprotein 1	Rattus norvegicus	22-33
8304052-1	1993	The bone sialoprotein osteopontin (OPN) promotes cell attachment and spreading through its RGD (Arg-Gly-Asp) sequence.	Glycine	100-103	secreted phosphoprotein 1	Rattus norvegicus	35-38
10713046-6	2000	A murine PTTG cDNA that encodes a variant C-terminal tail (Gly-Lys-Gly-Val-Arg-Ser-Asn-Gly-Cys-Lys-Asp-Leu-Val-Thr) was cloned.	Glycine	59-62	pituitary tumor-transforming gene 1	Mus musculus	9-13
8238541-11	1993	Although damage by either factor occurs by distinct mechanisms, glycine also appears to have effects that suppress the deleterious effects of Ca2+ so long as Caf increases are not overwhelming.	Glycine	64-71	lysine acetyltransferase 2B	Homo sapiens	158-161
10713046-6	2000	A murine PTTG cDNA that encodes a variant C-terminal tail (Gly-Lys-Gly-Val-Arg-Ser-Asn-Gly-Cys-Lys-Asp-Leu-Val-Thr) was cloned.	Glycine	67-70	pituitary tumor-transforming gene 1	Mus musculus	9-13
1600374-1	1992	This paper describes a method for the direct gas/liquid chromatographic (GC) analysis of 46 glycine-conjugated bile acids, which differ from one another in the number, position and configuration of the hydroxyl groups at positions C-2, C-3, C-4, C-6, C-7 and/or C-12.	Glycine	92-99	complement C6	Homo sapiens	246-249
10713047-4	2000	Urm1 is conjugated to target proteins, which requires the C-terminal glycine of Urm1.	Glycine	69-76	ubiquitin-related modifier URM1	Saccharomyces cerevisiae S288C	0-4
7690758-6	1993	A distinct loop configuration of VL-CDR3 appears in models having either a Pro, Gly, or Ala insertion at position 95A.	Glycine	80-83	CDR3	Homo sapiens	36-40
10713047-4	2000	Urm1 is conjugated to target proteins, which requires the C-terminal glycine of Urm1.	Glycine	69-76	ubiquitin-related modifier URM1	Saccharomyces cerevisiae S288C	80-84
10720722-2	2000	Two overlapping pathways could be postulated: (1) demethylenation followed by catechol-O-methyl-transferase (COMT) catalyzed methylation and/or glucuronidation/sulfatation; (2) N-dealkylation, deamination and only for MDA, MDMA, MDE oxidation to the corresponding benzoic acid derivatives conjugated with glycine.	Glycine	305-312	catechol-O-methyltransferase	Homo sapiens	78-107
8404890-4	1993	The highly conserved tripeptide sequence at the active site of aspartic proteinases, Asp-Thr(Ser)-Gly, is, however, replaced by Asp-Thr-Val in rabbit procathepsin E.	Glycine	98-101	cathepsin E	Oryctolagus cuniculus	150-164
8259556-1	1993	Recombinant staphylokinase (STAR) is produced as a 136 amino acid protein with NH2-terminal sequence Ser-Ser-Ser (mature STAR, HMW-STAR), which may be converted to lower molecular weight forms (LMW-STAR) by removal of the first six residues (yielding STAR-delta 6 with NH2-terminal Gly-Lys-Tyr-) or the first ten residues (yielding STAR-delta 10 with NH2-terminal Lys-Gly-Asp-).	Glycine	282-285	steroidogenic acute regulatory protein	Homo sapiens	28-32
1596690-2	1992	Milacemide is a glycine prodrug which is both an inhibitor and a substrate for monoamine oxidase-type B (MAO-B) and also an inhibitor of MAO-type A (MAO-A).	Glycine	16-23	monoamine oxidase A	Rattus norvegicus	137-147
1596690-2	1992	Milacemide is a glycine prodrug which is both an inhibitor and a substrate for monoamine oxidase-type B (MAO-B) and also an inhibitor of MAO-type A (MAO-A).	Glycine	16-23	monoamine oxidase A	Rattus norvegicus	149-154
1729723-2	1992	This enzyme, which has an apparent molecular mass of 100 kDa, performs a selective cleavage at the Xaa-Phe, Xaa-Leu, or Xaa-Ile bond (Xaa = Ser, Phe, Tyr, His, or Gly) of a number of peptide hormones, including atrial natriuretic factor, substance P, angiotensin II, bradykinin, somatostatin, neuromedins B and C, and litorin.	Glycine	163-166	bradykinin receptor B2 S homeolog	Xenopus laevis	267-277
8259556-1	1993	Recombinant staphylokinase (STAR) is produced as a 136 amino acid protein with NH2-terminal sequence Ser-Ser-Ser (mature STAR, HMW-STAR), which may be converted to lower molecular weight forms (LMW-STAR) by removal of the first six residues (yielding STAR-delta 6 with NH2-terminal Gly-Lys-Tyr-) or the first ten residues (yielding STAR-delta 10 with NH2-terminal Lys-Gly-Asp-).	Glycine	282-285	cilia and flagella associated protein 97	Homo sapiens	127-130
10720722-2	2000	Two overlapping pathways could be postulated: (1) demethylenation followed by catechol-O-methyl-transferase (COMT) catalyzed methylation and/or glucuronidation/sulfatation; (2) N-dealkylation, deamination and only for MDA, MDMA, MDE oxidation to the corresponding benzoic acid derivatives conjugated with glycine.	Glycine	305-312	catechol-O-methyltransferase	Homo sapiens	109-113
8259556-1	1993	Recombinant staphylokinase (STAR) is produced as a 136 amino acid protein with NH2-terminal sequence Ser-Ser-Ser (mature STAR, HMW-STAR), which may be converted to lower molecular weight forms (LMW-STAR) by removal of the first six residues (yielding STAR-delta 6 with NH2-terminal Gly-Lys-Tyr-) or the first ten residues (yielding STAR-delta 10 with NH2-terminal Lys-Gly-Asp-).	Glycine	368-371	steroidogenic acute regulatory protein	Homo sapiens	28-32
10677373-3	2000	One allele of the rfc gene contains a point mutation resulting in a Gly(345)--&gt;Arg substitution in the predicted amino acid sequence.	Glycine	68-71	solute carrier family 19 member 1	Homo sapiens	18-21
8259556-1	1993	Recombinant staphylokinase (STAR) is produced as a 136 amino acid protein with NH2-terminal sequence Ser-Ser-Ser (mature STAR, HMW-STAR), which may be converted to lower molecular weight forms (LMW-STAR) by removal of the first six residues (yielding STAR-delta 6 with NH2-terminal Gly-Lys-Tyr-) or the first ten residues (yielding STAR-delta 10 with NH2-terminal Lys-Gly-Asp-).	Glycine	368-371	cilia and flagella associated protein 97	Homo sapiens	127-130
1717598-7	1991	This was further substantiated by the observation that MON-101 and MON-102 specifically recognized a conjugate between bovine serum albumin and the synthetic peptide Phe-Glu-Pro-Glu-His-Asp-Tyr-Pro-Gly-Leu-Gly-Lys based upon the deduced amino acid sequence of the predicted epitope region in 7B2.	Glycine	198-201	secretogranin V	Rattus norvegicus	292-295
10710290-2	2000	A peptide that shared significant homology with the amino acids located between the residues Gly-Xaa-Gly-Xaa-Xaa-Gly721 and Lys742, the residues predicted to be important for ATP binding of the ErbB3 and ErbB2 receptors, was identified to be interacting with the AT2 receptor.	Glycine	93-96	erb-b2 receptor tyrosine kinase 3	Homo sapiens	194-199
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	41-44	thyrotropin releasing hormone	Rattus norvegicus	37-40
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	41-44	thyrotropin releasing hormone	Rattus norvegicus	125-128
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	41-44	thyrotropin releasing hormone	Rattus norvegicus	164-171
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	41-44	thyrotropin releasing hormone	Rattus norvegicus	125-128
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	37-40
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	125-128
8105102-1	1993	Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) is a recently isolated peptide that belongs to a larger family that includes Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and MIF-1 (Pro-Leu-Gly-NH2).	Glycine	25-28	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	6-11
8105102-1	1993	Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) is a recently isolated peptide that belongs to a larger family that includes Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and MIF-1 (Pro-Leu-Gly-NH2).	Glycine	25-28	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	115-120
8105102-1	1993	Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) is a recently isolated peptide that belongs to a larger family that includes Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and MIF-1 (Pro-Leu-Gly-NH2).	Glycine	25-28	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	115-120
8105102-1	1993	Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) is a recently isolated peptide that belongs to a larger family that includes Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and MIF-1 (Pro-Leu-Gly-NH2).	Glycine	134-137	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	6-11
8105102-1	1993	Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) is a recently isolated peptide that belongs to a larger family that includes Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and MIF-1 (Pro-Leu-Gly-NH2).	Glycine	134-137	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	115-120
8105102-1	1993	Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) is a recently isolated peptide that belongs to a larger family that includes Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) and MIF-1 (Pro-Leu-Gly-NH2).	Glycine	134-137	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	115-120
11255560-1	2000	Gonadotropin-releasing hormone (GnRH) is a decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) which is produced from a precursor polypeptide in hypothalamic neurons and secreted in a pulsatile fashion to stimulate the secretion of LH and FSH via its interaction with a cognate receptor on gonadotropes.	Glycine	77-80	gonadotropin releasing hormone 1	Homo sapiens	0-30
8339246-1	1993	The Tyr-Ile-Gly-Ser-Arg (YIGSR) peptide derived from the laminin B1 chain has been shown to decrease tumor growth and metastasis.	Glycine	12-15	laminin B1	Mus musculus	57-73
8471031-0	1993	Importance of the evolutionarily conserved glycine residue in the N-terminal region of human cystatin C (Gly-11) for cysteine endopeptidase inhibition.	Glycine	43-50	cystatin C	Homo sapiens	93-103
8471031-1	1993	Human cystatin C variants in which the evolutionarily conserved Gly-11 residue has been replaced by residues with positively charged (Arg), negatively charged (Glu), bulky hydrophobic (Trp), or small (Ser or Ala) side-chains have been produced by site-directed mutagenesis and expression in Escherichia coli.	Glycine	64-67	cystatin C	Homo sapiens	6-16
8471031-10	1993	These data indicate that the crucial feature of the conserved Gly residue in position 11 of wild-type cystatin C is that this residue, devoid of a side-chain, will allow the N-terminal segment of cystatin C to adopt a conformation suitable for interaction with the substrate-binding pockets of cysteine endopeptidases, resulting in high-affinity binding and efficient inhibition.	Glycine	62-65	cystatin C	Homo sapiens	102-112
8471031-10	1993	These data indicate that the crucial feature of the conserved Gly residue in position 11 of wild-type cystatin C is that this residue, devoid of a side-chain, will allow the N-terminal segment of cystatin C to adopt a conformation suitable for interaction with the substrate-binding pockets of cysteine endopeptidases, resulting in high-affinity binding and efficient inhibition.	Glycine	62-65	cystatin C	Homo sapiens	196-206
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	125-128
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	37-40
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	125-128
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	125-128
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	37-40
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	125-128
1800945-5	1991	The effect of zinc deficiency on the TRH-Gly-IR HPLC profile of rat brain was to reduce selectively the are of the peaks for TRH-Gly and other low molecular weight pro-TRH peptide fragments with a C-terminal Gly compared to the corresponding TRH-Gly-IR peaks of the control group.	Glycine	129-132	thyrotropin releasing hormone	Rattus norvegicus	125-128
8445645-5	1993	It is speculated that the ancestral form of the A motif might have comprised a loop rich in Gly residues, GXGGXGK[ST], resembling that in NifH proteins and ArsA.	Glycine	92-95	arylsulfatase A	Homo sapiens	156-160
11255560-1	2000	Gonadotropin-releasing hormone (GnRH) is a decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) which is produced from a precursor polypeptide in hypothalamic neurons and secreted in a pulsatile fashion to stimulate the secretion of LH and FSH via its interaction with a cognate receptor on gonadotropes.	Glycine	77-80	gonadotropin releasing hormone 1	Homo sapiens	32-36
11255560-1	2000	Gonadotropin-releasing hormone (GnRH) is a decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) which is produced from a precursor polypeptide in hypothalamic neurons and secreted in a pulsatile fashion to stimulate the secretion of LH and FSH via its interaction with a cognate receptor on gonadotropes.	Glycine	93-96	gonadotropin releasing hormone 1	Homo sapiens	0-30
8485301-9	1993	E-MLT, when succinylated at the N-terminal glycine (E-MLT-suc), forms a stronger hybrid with MLT-Me, possibly as a result of increased electrostatic interaction between equal but opposite charges in E-MLT-suc (net charge -6) and MLT-Me (net charge +6).	Glycine	43-50	MALT1 paracaspase	Homo sapiens	2-5
11255560-1	2000	Gonadotropin-releasing hormone (GnRH) is a decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) which is produced from a precursor polypeptide in hypothalamic neurons and secreted in a pulsatile fashion to stimulate the secretion of LH and FSH via its interaction with a cognate receptor on gonadotropes.	Glycine	93-96	gonadotropin releasing hormone 1	Homo sapiens	32-36
8485301-9	1993	E-MLT, when succinylated at the N-terminal glycine (E-MLT-suc), forms a stronger hybrid with MLT-Me, possibly as a result of increased electrostatic interaction between equal but opposite charges in E-MLT-suc (net charge -6) and MLT-Me (net charge +6).	Glycine	43-50	MALT1 paracaspase	Homo sapiens	54-57
8485301-9	1993	E-MLT, when succinylated at the N-terminal glycine (E-MLT-suc), forms a stronger hybrid with MLT-Me, possibly as a result of increased electrostatic interaction between equal but opposite charges in E-MLT-suc (net charge -6) and MLT-Me (net charge +6).	Glycine	43-50	MALT1 paracaspase	Homo sapiens	54-57
1659747-9	1991	In the third experiment the RGDS peptide (ARG-GLY-ASP-SER), a blocker of GPIIb/IIIa platelet receptor dose dependently inhibited platelet aggregation by 93 +/- 17%.	Glycine	46-49	ral guanine nucleotide dissociation stimulator	Homo sapiens	28-32
8485301-9	1993	E-MLT, when succinylated at the N-terminal glycine (E-MLT-suc), forms a stronger hybrid with MLT-Me, possibly as a result of increased electrostatic interaction between equal but opposite charges in E-MLT-suc (net charge -6) and MLT-Me (net charge +6).	Glycine	43-50	MALT1 paracaspase	Homo sapiens	54-57
10906770-4	2000	Third, rp66 with Met-Gly at the N-terminus was produced in transformed cells (Met-Gly-rp66).	Glycine	21-24	retinol binding protein 3	Homo sapiens	7-11
8485301-9	1993	E-MLT, when succinylated at the N-terminal glycine (E-MLT-suc), forms a stronger hybrid with MLT-Me, possibly as a result of increased electrostatic interaction between equal but opposite charges in E-MLT-suc (net charge -6) and MLT-Me (net charge +6).	Glycine	43-50	MALT1 paracaspase	Homo sapiens	54-57
10906770-4	2000	Third, rp66 with Met-Gly at the N-terminus was produced in transformed cells (Met-Gly-rp66).	Glycine	21-24	retinol binding protein 3	Homo sapiens	86-90
10906770-4	2000	Third, rp66 with Met-Gly at the N-terminus was produced in transformed cells (Met-Gly-rp66).	Glycine	82-85	retinol binding protein 3	Homo sapiens	7-11
8383813-17	1993	antagonized increases in levels of cyclic GMP in the cerebellum of the mouse, induced by the intracerebellar administration of NMDA and D-serine, agonists of the NMDA and the NMDA-associated glycine recognition sites, respectively.	Glycine	191-198	5'-nucleotidase, cytosolic II	Mus musculus	42-45
1909780-8	1991	Serum TRH-Gly concentrations were highest (mean 417 +/- 26 pmol/L) on the 2nd postnatal day and gradually decreased to the adult level by 35 d. Changes in the TRH-Gly/TRH ratio were inversely correlated with tissue TRH concentrations in hypothalamus, pancreas, and liver.	Glycine	163-166	thyrotropin releasing hormone	Rattus norvegicus	159-162
1909780-8	1991	Serum TRH-Gly concentrations were highest (mean 417 +/- 26 pmol/L) on the 2nd postnatal day and gradually decreased to the adult level by 35 d. Changes in the TRH-Gly/TRH ratio were inversely correlated with tissue TRH concentrations in hypothalamus, pancreas, and liver.	Glycine	163-166	thyrotropin releasing hormone	Rattus norvegicus	159-162
1469085-6	1992	A synthetic peptide of the Arg-Gly-Asp (RGD) domain in entactin, SIGFRGDGQTC (S-RGD), mediated PMN adhesion and chemotaxis, and preexposure of PMN to S-RGD blocked PMN adhesion and chemotaxis induced by entactin without diminishing the adhesive and chemotactic activities of fMLP.	Glycine	31-34	nidogen 1	Homo sapiens	55-63
10906770-4	2000	Third, rp66 with Met-Gly at the N-terminus was produced in transformed cells (Met-Gly-rp66).	Glycine	82-85	retinol binding protein 3	Homo sapiens	86-90
1469085-6	1992	A synthetic peptide of the Arg-Gly-Asp (RGD) domain in entactin, SIGFRGDGQTC (S-RGD), mediated PMN adhesion and chemotaxis, and preexposure of PMN to S-RGD blocked PMN adhesion and chemotaxis induced by entactin without diminishing the adhesive and chemotactic activities of fMLP.	Glycine	31-34	nidogen 1	Homo sapiens	203-211
1909780-8	1991	Serum TRH-Gly concentrations were highest (mean 417 +/- 26 pmol/L) on the 2nd postnatal day and gradually decreased to the adult level by 35 d. Changes in the TRH-Gly/TRH ratio were inversely correlated with tissue TRH concentrations in hypothalamus, pancreas, and liver.	Glycine	163-166	thyrotropin releasing hormone	Rattus norvegicus	159-162
10906770-6	2000	MBP-Ser-Ser-rp66 and Met-Gly-rp66 were readily purified in sufficient amounts for labeling with 2, 4-dinitrophenyl groups and beta-D-galactosidase from E. coli, but pol-rp66 and Ser-Ser-rp66 were not for enzyme-labeling.	Glycine	25-28	retinol binding protein 3	Homo sapiens	29-33
10906770-6	2000	MBP-Ser-Ser-rp66 and Met-Gly-rp66 were readily purified in sufficient amounts for labeling with 2, 4-dinitrophenyl groups and beta-D-galactosidase from E. coli, but pol-rp66 and Ser-Ser-rp66 were not for enzyme-labeling.	Glycine	25-28	retinol binding protein 3	Homo sapiens	29-33
10906770-6	2000	MBP-Ser-Ser-rp66 and Met-Gly-rp66 were readily purified in sufficient amounts for labeling with 2, 4-dinitrophenyl groups and beta-D-galactosidase from E. coli, but pol-rp66 and Ser-Ser-rp66 were not for enzyme-labeling.	Glycine	25-28	retinol binding protein 3	Homo sapiens	29-33
1327760-2	1992	It has two -Cys-Gly-His-Cys- sequences which represent two independently acting catalytic sites of PDI activity.	Glycine	16-19	prolyl 4-hydroxylase subunit beta	Homo sapiens	99-102
10654085-8	1999	Tat2p can take up Phe, Trp and Tyr; Put4p can transport Ala, Gly and Pro; while Can1p, Lyp1p and the previously uncharacterized Alp1p are specific for the cationic amino acids.	Glycine	61-64	proline permease PUT4	Saccharomyces cerevisiae S288C	36-41
1327760-4	1992	When either one or both of the -Cys-Gly-His-Cys- sequences was converted to -Ser-Gly-His-Cys-, a tetramer was formed as with wild-type PDI/beta-subunit.	Glycine	36-39	prolyl 4-hydroxylase subunit beta	Homo sapiens	135-138
1711498-5	1991	The glycine-rich as repeat region characteristic of sKer is also present in a shortened form in the cKer sequence.	Glycine	4-11	keratin	Gallus gallus	52-56
11498928-4	1999	Corticosterone (CORT), progesterone (P) and dexamethasone (DEX) had rapid effects on the glycine uptake.	Glycine	89-96	cortistatin	Homo sapiens	16-20
1901802-0	1991	Role of glycine-82 as a pivot point during the transition from the inactive to the active form of the yeast Ras2 protein.	Glycine	8-15	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	108-112
1901802-4	1991	We have found that the replacement of glycine-82 of the Ras2 protein by serine resulted in an increased rate of dissociation of Gpp(NH)p, a nonhydrolysable analog of GTP, while the GDP dissociation rate was not significantly modified.	Glycine	38-45	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	56-60
1484502-2	1992	DSP is rich in aspartic acid, glutamic acid, glycine and serine, but contains no cysteine or phosphate.	Glycine	45-52	dentin sialophosphoprotein	Homo sapiens	0-3
10545445-6	1999	Interestingly, the prp2-1 allele contains a point mutation that changes glycine to aspartate, indicating that EMT1-201 does not act by classical missense suppression.	Glycine	72-79	EMT1	Saccharomyces cerevisiae S288C	110-114
1361061-1	1992	The clock gene period determines biological rhythmicity in Drosophila melanogaster and encodes a protein characterized by an alternating series of threonine-glycine pairs.	Glycine	157-164	Clock	Drosophila melanogaster	4-9
1904138-3	1991	We have used this TRH-Gly RIA to determine whether this TRH precursor peptide is also elevated in CSF from MS and Alzheimer"s (ALZ) disease patients in comparison with the corresponding levels in non-central nervous system disease (control) patients.	Glycine	22-25	thyrotropin releasing hormone	Homo sapiens	18-21
10934518-7	1999	The MBP was further purified by cation exchange chromatography and buffers containing glycine and salts.	Glycine	86-93	myelin basic protein	Homo sapiens	4-7
1904138-3	1991	We have used this TRH-Gly RIA to determine whether this TRH precursor peptide is also elevated in CSF from MS and Alzheimer"s (ALZ) disease patients in comparison with the corresponding levels in non-central nervous system disease (control) patients.	Glycine	22-25	thyrotropin releasing hormone	Homo sapiens	56-59
1904138-5	1991	Cation exchange and exclusion chromatography of extracts of mixtures of CSF and synthetic TRH-Gly revealed two peaks of TRH-Gly-IR.	Glycine	94-97	thyrotropin releasing hormone	Homo sapiens	90-93
1904138-5	1991	Cation exchange and exclusion chromatography of extracts of mixtures of CSF and synthetic TRH-Gly revealed two peaks of TRH-Gly-IR.	Glycine	94-97	thyrotropin releasing hormone	Homo sapiens	120-123
1904138-8	1991	Reverse-phase high-pressure liquid chromatography of pooled extracts of normal CSF revealed that about a third of the total TRH-Gly-IR coeluted with synthetic TRH-Gly.	Glycine	128-131	thyrotropin releasing hormone	Homo sapiens	124-127
1848009-1	1991	Native lecithin-cholesterol acyltransferase (LCAT; phosphatidylcholine-sterol acyltransferase; phosphatidylcholine:sterol O-acyltransferase, EC 2.3.1.43) protein, and LCAT in which either or both of the enzyme free cysteines had been replaced with glycine residues by site-directed mutagenesis, has been expressed in cultured Chinese hamster ovary cells stably transfected with the human LCAT gene.	Glycine	248-255	phosphatidylcholine-sterol acyltransferase	Cricetulus griseus	7-43
1491013-1	1992	Skeletal muscle actin was lightly digested by proteinase K, which cleaved the peptide bond between Met-47 and Gly-48, producing a C-terminal 35 kDa fragment.	Glycine	110-113	endogenous retrovirus group K member 7	Homo sapiens	46-56
1326944-4	1992	Tetrapeptide RGDS (Arg-Gly-Asp-Ser), which blocks the interaction of ligands such as fibrinogen with platelet integrin alpha IIb beta 3 (GPIIb-IIIa), inhibited only the late-phase PtdIns(3,4)P2 accumulation that was associated with added Ca2+.	Glycine	23-26	ral guanine nucleotide dissociation stimulator	Homo sapiens	13-17
10483786-1	1999	The Trembler mouse (Tr) suffers from a dominantly inherited autosomal mutation (glycine to aspartic acid.	Glycine	80-87	peripheral myelin protein 22	Mus musculus	4-12
1515027-3	1992	The masu salmon sGnRH precursor was composed of a signal peptide, sGnRH and a GnRH-associated peptide (GAP) which was connected to sGnRH by a Gly-Lys-Arg sequence.	Glycine	142-145	gonadotropin releasing hormone 1	Homo sapiens	17-21
1750929-10	1991	The minimal active sequence within CS5, the tetrapeptide Arg-Glu-Asp-Val (REDV), is somewhat related to the Arg-Gly-Asp-Ser (RGDS) sequence that represents a major active site in the central cell-binding domain (CCBD) of fibronectin.	Glycine	112-115	ral guanine nucleotide dissociation stimulator	Homo sapiens	125-129
10447650-9	1999	A nucleotide exchange was detected at position 14568 replacing a glycine by serine in the ND6 gene.	Glycine	65-72	mitochondrially encoded NADH dehydrogenase 6	Homo sapiens	90-93
1996959-2	1991	Leucocyte elastase in catalytic amounts was observed to rapidly cleave the Val-10-Gly-11 bond of the human cysteine-proteinase inhibitor cystatin C at neutral pH.	Glycine	82-85	cystatin C	Homo sapiens	137-147
1316608-5	1992	A comparison of the pRB binding sites of the sequenced genital tract HPVs revealed a consistent amino acid difference (aspartic acid/glycine) between the high-risk and low-risk viruses.	Glycine	133-140	RB transcriptional corepressor 1	Homo sapiens	20-23
10438540-8	1999	Our analysis shows that residues Ile(711), Leu(712), Phe(713), Glu(927), and Gly(1413) are essential for Ycf1p expression.	Glycine	77-80	ATP-binding cassette glutathione S-conjugate transporter YCF1	Saccharomyces cerevisiae S288C	105-110
1372753-6	1992	Substitution of this glycine by cysteine in the human PR (hPR) abrogated binding of RU486 but not that of an agonist.	Glycine	21-28	haptoglobin-related protein	Homo sapiens	54-56
1372753-6	1992	Substitution of this glycine by cysteine in the human PR (hPR) abrogated binding of RU486 but not that of an agonist.	Glycine	21-28	haptoglobin-related protein	Homo sapiens	58-61
1756615-5	1991	BAT activity from dog liver formed bile acid conjugates with taurine exclusively, whereas BAT activity from each of the other species formed conjugates with both taurine and glycine.	Glycine	174-181	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	90-93
1756615-7	1991	Biliary composition of glycine and taurine bile acid conjugates could partly be accounted for by substrate affinity (Km) and turnover number (Vmax) of BAT activity.	Glycine	23-30	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	151-154
10438540-9	1999	Five other amino acids, Gly(663), Gly(756), Asp(777), Gly(1306), and Gly(1311), are critical for Ycf1p function, and two residues, Glu(709) and Asp(821), are unnecessary for Ycf1p biogenesis and function.	Glycine	24-27	ATP-binding cassette glutathione S-conjugate transporter YCF1	Saccharomyces cerevisiae S288C	97-102
2246265-8	1990	MAP also cleaved methionine from other tripeptides whose penultimate amino acid residue is relatively small and/or uncharged (e.g. Pro, Gly, Val, Thr, or Ser) but not when bulky and/or charged (Arg.	Glycine	136-139	methionine aminopeptidase	Saccharomyces cerevisiae S288C	0-3
10417409-8	1999	The Ramachandran (Phi,Psi) angles around Gly in the consensus sequence show clustering in the region which is disallowed for non-glycyl residues.	Glycine	41-44	glucose-6-phosphate isomerase	Homo sapiens	18-21
1567180-6	1992	Although the function of this protein in tumor cells is not known, OPN contains a conserved GRGDS (glycine-arginine-glycine-aspartic acid-serine) amino acid sequence, which may function as a cell attachment site for this protein.	Glycine	99-106	secreted phosphoprotein 1	Mus musculus	67-70
1567180-6	1992	Although the function of this protein in tumor cells is not known, OPN contains a conserved GRGDS (glycine-arginine-glycine-aspartic acid-serine) amino acid sequence, which may function as a cell attachment site for this protein.	Glycine	116-123	secreted phosphoprotein 1	Mus musculus	67-70
1730754-5	1992	We refer to this configuration, which is also found in the hnRNP A/B proteins of vertebrates, as 2 x RBD-Gly.	Glycine	105-108	squid	Drosophila melanogaster	59-68
1980647-4	1990	Glycine potentiated the [Ca2+]i response to NMDA, and high concentrations of glycine selectively overcame blockade by kynurenic acid, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), and cis-piperidine-2,3-dicarboxylic acid (PDA).	Glycine	0-7	carbonic anhydrase 2	Gallus gallus	25-28
1980647-4	1990	Glycine potentiated the [Ca2+]i response to NMDA, and high concentrations of glycine selectively overcame blockade by kynurenic acid, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), and cis-piperidine-2,3-dicarboxylic acid (PDA).	Glycine	77-84	carbonic anhydrase 2	Gallus gallus	25-28
10414965-5	1999	Substitution of these four amino acids-glycine 171, lysine 173, glutamate 179, and arginine 180-into the beta2 subunit was sufficient to enable the beta2 subunit to homo-oligomerize.	Glycine	39-46	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	105-110
1660812-6	1991	These results suggest that the constraints of forming a flexible loop within the third complementarity-determining region, is a factor in the preference for a particular reading frame in Ig H D. For the TcR beta D segments, glycine is specified in most reading frames, and no significant preference is observed.	Glycine	224-231	immunoglobulin heavy locus	Homo sapiens	187-191
1839957-8	1991	Moreover, the attachment of IFN-gamma-treated Pam-T cells as well as non-treated cells to FN was blocked by the synthetic peptide Arg-Gly-Asp-Ser (RGDS), but not by the control peptide Arg-Gly-Glu-Ser.	Glycine	134-137	ral guanine nucleotide dissociation stimulator	Homo sapiens	147-151
1701089-5	1990	The results indicate that the CAGY region, particularly the glycine residue at position 36 in the beta subunit, is essential for the production of hCG.	Glycine	60-67	chorionic gonadotropin subunit beta 5	Homo sapiens	147-150
10414965-5	1999	Substitution of these four amino acids-glycine 171, lysine 173, glutamate 179, and arginine 180-into the beta2 subunit was sufficient to enable the beta2 subunit to homo-oligomerize.	Glycine	39-46	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	148-153
10400630-9	1999	Moreover, like the Killer-of-prune mutation in Drosophila NDK and the neuroblastoma Ser120 --&gt; Gly mutation in human NDK-A/Nm23-H1, the Ser122 --&gt; Pro substitution in NDK-B affects the stability of the protein toward heat and urea.	Glycine	98-101	abnormal wing discs	Drosophila melanogaster	19-34
1718750-2	1991	One peptide, His-Gly-Arg-Val-Gly-Ile-Tyr-Phe-Gly-Met-Lys (peptide 11; Ile, isoleucine) is antigenic and binds with a high affinity to a monoclonal antibody that recognizes the native beta 2 subunit.	Glycine	17-20	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	183-189
1718750-2	1991	One peptide, His-Gly-Arg-Val-Gly-Ile-Tyr-Phe-Gly-Met-Lys (peptide 11; Ile, isoleucine) is antigenic and binds with a high affinity to a monoclonal antibody that recognizes the native beta 2 subunit.	Glycine	29-32	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	183-189
1718750-2	1991	One peptide, His-Gly-Arg-Val-Gly-Ile-Tyr-Phe-Gly-Met-Lys (peptide 11; Ile, isoleucine) is antigenic and binds with a high affinity to a monoclonal antibody that recognizes the native beta 2 subunit.	Glycine	29-32	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	183-189
2173165-0	1990	Evidence for a glycine residue at position 316 in human protein C inhibitor.	Glycine	15-22	serpin family A member 5	Homo sapiens	56-75
10400630-9	1999	Moreover, like the Killer-of-prune mutation in Drosophila NDK and the neuroblastoma Ser120 --&gt; Gly mutation in human NDK-A/Nm23-H1, the Ser122 --&gt; Pro substitution in NDK-B affects the stability of the protein toward heat and urea.	Glycine	98-101	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	120-125
10400630-9	1999	Moreover, like the Killer-of-prune mutation in Drosophila NDK and the neuroblastoma Ser120 --&gt; Gly mutation in human NDK-A/Nm23-H1, the Ser122 --&gt; Pro substitution in NDK-B affects the stability of the protein toward heat and urea.	Glycine	98-101	NME/NM23 nucleoside diphosphate kinase 1	Homo sapiens	126-133
1797805-1	1991	Materials to enhance cell adhesion were synthesized by surface integration of peptide, Arg-Gly-Asp-Ser(RGDS), which is an active-site sequence of cell-adhesive proteins.	Glycine	91-94	ral guanine nucleotide dissociation stimulator	Homo sapiens	103-107
10432630-2	1999	Export of colicin V is dependent on specific ABC (ATP-binding cassette) secretion proteins which recognize a double-glycine-type leader peptide on the immature colicin V bacteriocin.	Glycine	116-123	Colicin V	Escherichia coli	10-19
1939089-3	1991	Based on the deduced amino acid sequences of these cDNAs, MMCP-5 is synthesized as a 247-amino acid preproenzyme composed of a novel 19-residue hydrophobic signal peptide, a Gly-Glu activation peptide not present in other mast cell chymases, and a 226-amino acid protein that represents the mature enzyme.	Glycine	174-177	chymase 1, mast cell	Mus musculus	58-64
2162041-1	1990	Rat thyrotropin-releasing hormone (TRH) prohormone contains five copies of the TRH progenitor sequence Gln-His-Pro-Gly linked together by connecting sequences whose biological activity is unknown.	Glycine	115-118	thyrotropin releasing hormone	Rattus norvegicus	4-33
2162041-1	1990	Rat thyrotropin-releasing hormone (TRH) prohormone contains five copies of the TRH progenitor sequence Gln-His-Pro-Gly linked together by connecting sequences whose biological activity is unknown.	Glycine	115-118	thyrotropin releasing hormone	Rattus norvegicus	35-38
2162041-1	1990	Rat thyrotropin-releasing hormone (TRH) prohormone contains five copies of the TRH progenitor sequence Gln-His-Pro-Gly linked together by connecting sequences whose biological activity is unknown.	Glycine	115-118	thyrotropin releasing hormone	Rattus norvegicus	79-82
1725868-12	1991	(e.g. Gly, Ala and Ser) which are abundantly represented in fibroin and therefore directly related to the expression of fibroin.	Glycine	6-9	fibroin light chain	Bombyx mori	60-67
10432630-2	1999	Export of colicin V is dependent on specific ABC (ATP-binding cassette) secretion proteins which recognize a double-glycine-type leader peptide on the immature colicin V bacteriocin.	Glycine	116-123	Colicin V	Escherichia coli	160-169
1725868-12	1991	(e.g. Gly, Ala and Ser) which are abundantly represented in fibroin and therefore directly related to the expression of fibroin.	Glycine	6-9	fibroin light chain	Bombyx mori	120-127
2109688-2	1990	Two antisera (Anti-P7 and Anti-P10) were raised against (-Gln-His-Pro-Gly-) elongated peptides: P7 Gln-His-Pro-Gly-Lys-Arg-Phe) and P10 (Ser-Lys-Arg-Gln-His-Pro-Gly-Lys-Arg-Phe).	Glycine	70-73	S100 calcium binding protein A10 (calpactin)	Mus musculus	31-34
10339470-8	1999	Sequencing of amplicons showed a homogeneous restricted variability in the ORF26 region, characteristic of the minority subgroup B defined by Zong, and responsible for isoleucine and glycine substitutions at amino acid positions 134 and 167.	Glycine	183-190	ORF26	Human gammaherpesvirus 8	75-80
2328721-8	1990	The ypt1, ypt2 and ypt3 genes, but not ryh1, constitute a family, their products having double cysteine as their C terminus and serine in place of a glycine residue highly conserved in ras proteins (mammalian Gly-12 or S. pombe Gly-17).	Glycine	149-156	RAB1A, member RAS oncogene family	Homo sapiens	4-8
2328721-8	1990	The ypt1, ypt2 and ypt3 genes, but not ryh1, constitute a family, their products having double cysteine as their C terminus and serine in place of a glycine residue highly conserved in ras proteins (mammalian Gly-12 or S. pombe Gly-17).	Glycine	209-212	RAB1A, member RAS oncogene family	Homo sapiens	4-8
2328721-8	1990	The ypt1, ypt2 and ypt3 genes, but not ryh1, constitute a family, their products having double cysteine as their C terminus and serine in place of a glycine residue highly conserved in ras proteins (mammalian Gly-12 or S. pombe Gly-17).	Glycine	228-231	RAB1A, member RAS oncogene family	Homo sapiens	4-8
1910037-9	1991	The Rsr1 protein shares with human Rap1 GTPases the four specific motifs, i.e. Gly-12, residues 32-40, Ala-59, and residues 64-70, that are required for GAP3-dependent activation of the Rap1 GTPases.	Glycine	79-82	Ras family GTPase RSR1	Saccharomyces cerevisiae S288C	4-8
1716439-7	1991	rMNK1 and mMNK1 differed from a recently reported MAP-2 kinase cDNA, termed ERK1, because of a nonconservative change in position 82, from Gly in ERK1 to Arg in rMNK1.	Glycine	139-142	mitogen activated protein kinase 3	Rattus norvegicus	0-5
1716439-7	1991	rMNK1 and mMNK1 differed from a recently reported MAP-2 kinase cDNA, termed ERK1, because of a nonconservative change in position 82, from Gly in ERK1 to Arg in rMNK1.	Glycine	139-142	mitogen-activated protein kinase 3	Mus musculus	10-15
10224104-1	1999	In eukaryotes, two isozymes (I and II) of methionine aminopeptidase (MetAP) catalyze the removal of the initiator methionine if the penultimate residue has a small radius of gyration (glycine, alanine, serine, threonine, proline, valine, and cysteine).	Glycine	184-191	methionine aminopeptidase	Saccharomyces cerevisiae S288C	42-67
1716439-7	1991	rMNK1 and mMNK1 differed from a recently reported MAP-2 kinase cDNA, termed ERK1, because of a nonconservative change in position 82, from Gly in ERK1 to Arg in rMNK1.	Glycine	139-142	mitogen activated protein kinase 3	Rattus norvegicus	76-80
1716439-7	1991	rMNK1 and mMNK1 differed from a recently reported MAP-2 kinase cDNA, termed ERK1, because of a nonconservative change in position 82, from Gly in ERK1 to Arg in rMNK1.	Glycine	139-142	mitogen activated protein kinase 3	Rattus norvegicus	146-150
1692822-8	1990	Valine and glycine were found at positions 85 and 86 of the DR1 beta 1 chain in DR1 molecules from six of the nine lymphoblastoid cell lines, whereas alanine and valine were found in the three variant (Dw20) DR1-positive cells.	Glycine	11-18	down-regulator of transcription 1	Homo sapiens	60-63
10224104-1	1999	In eukaryotes, two isozymes (I and II) of methionine aminopeptidase (MetAP) catalyze the removal of the initiator methionine if the penultimate residue has a small radius of gyration (glycine, alanine, serine, threonine, proline, valine, and cysteine).	Glycine	184-191	methionine aminopeptidase	Saccharomyces cerevisiae S288C	69-74
1692822-8	1990	Valine and glycine were found at positions 85 and 86 of the DR1 beta 1 chain in DR1 molecules from six of the nine lymphoblastoid cell lines, whereas alanine and valine were found in the three variant (Dw20) DR1-positive cells.	Glycine	11-18	down-regulator of transcription 1	Homo sapiens	80-83
1751226-4	1991	Furthermore, incorporation of the well known cell adhesive ligand Arg-Gly-Asp-Ser (RGDS) peptidyl moiety into the above co-polymer resulted, on UV light irradiation, in a three-dimensional hydrophilic gel matrix containing cell adhesive ligands.	Glycine	70-73	ral guanine nucleotide dissociation stimulator	Homo sapiens	83-87
1692822-8	1990	Valine and glycine were found at positions 85 and 86 of the DR1 beta 1 chain in DR1 molecules from six of the nine lymphoblastoid cell lines, whereas alanine and valine were found in the three variant (Dw20) DR1-positive cells.	Glycine	11-18	down-regulator of transcription 1	Homo sapiens	80-83
10206186-7	1999	Previous studies showed that ethanol inhibition of NMDA receptor function in cerebellar granule neurons resulted from an ethanol-induced decrease in potency of the co-agonist, glycine, and that this effect of ethanol was blocked by inhibitors of protein kinase C. Our current results suggest that the lower potency of ethanol to inhibit the response of NMDA receptors when cerebellar granule neurons are expressing a greater proportion of NR2B subunits is a result of the higher affinity of the NMDA receptors for endogenous levels of glycine at this point in time.	Glycine	176-183	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	439-443
2352355-2	1990	GAA is formed from arginine and glycine by glycine-amidinotransferase (GAT) mainly in the kidney.	Glycine	32-39	glycine amidinotransferase	Rattus norvegicus	43-69
9925650-8	1999	The Turkish proband, in contrast, was homozygous for a G(1064)-->T substitution in exon 10 of the hLAL gene which converts the completely conserved glycine (GGG) residue at position 321 of the mature enzyme to tryptophan (TGG).	Glycine	148-155	lipase A, lysosomal acid type	Homo sapiens	98-102
2352355-2	1990	GAA is formed from arginine and glycine by glycine-amidinotransferase (GAT) mainly in the kidney.	Glycine	32-39	glycine amidinotransferase	Rattus norvegicus	71-74
1965949-1	1990	The platelet adhesion on adhesive protein-coated surfaces was significantly reduced by the addition of the synthetic tetrapeptide, RGDS (Arg-Gly-Asp-Ser), which was identified as the common amino acid sequence of adhesive site of adhesive proteins.	Glycine	141-144	ral guanine nucleotide dissociation stimulator	Homo sapiens	131-135
10024091-4	1999	Recently, it was reported that GLP-1 became resistant to DPPIV when the alanine residue at position 8 was replaced by a glycine (GLP-1-Gly8).	Glycine	120-127	glucagon like peptide 1 receptor	Homo sapiens	129-134
9858549-6	1999	Recruitment of only the glycine-rich C-terminal domain of hnRNP A1, which is capable of interactions with other proteins, is sufficient to repress exon splicing.	Glycine	24-31	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	58-66
33804477-4	2021	To disrupt autocrine/paracrine loop in TNBC models in addition to mediating anti-EGFR tumor growth signaling and anti-VEGFR2 angiogenic pathway, we generated a BsAb co-targeting EGFR and VEGFR2 (designated as anti-EGFR/VEGFR2 BsAb), using publicly available sequences in which cetuximab IgG backbone is connected to the single chain variable fragment (scFv) of ramucirumab via a glycine linker.	Glycine	379-386	kinase insert domain protein receptor	Mus musculus	187-193
9852045-8	1998	Substitution of these amino acids demonstrated that a glycine residue at position 433 in STAT5B and a glutamic residue at a similar position in STAT5A determined the DNA binding specificity.	Glycine	54-61	signal transducer and activator of transcription 5B	Homo sapiens	89-95
33804477-4	2021	To disrupt autocrine/paracrine loop in TNBC models in addition to mediating anti-EGFR tumor growth signaling and anti-VEGFR2 angiogenic pathway, we generated a BsAb co-targeting EGFR and VEGFR2 (designated as anti-EGFR/VEGFR2 BsAb), using publicly available sequences in which cetuximab IgG backbone is connected to the single chain variable fragment (scFv) of ramucirumab via a glycine linker.	Glycine	379-386	kinase insert domain protein receptor	Mus musculus	187-193
9851443-4	1998	We detected an A-to-G transition in the PS-1 gene, resulting in a glutamic acid (Glu)-to-glycine (Gly) substitution at codon 318 in 2 familial and 2 sporadic AD patients.	Glycine	89-96	presenilin 1	Homo sapiens	40-44
30576235-11	2019	Interestingly, when the Gly between K330/E332 and R3-pCt was mutated (G334A), hTREK-2 was tonic activated with reversed responses to ATP and acidic pHi.	Glycine	24-27	glucose-6-phosphate isomerase	Homo sapiens	148-151
9851443-4	1998	We detected an A-to-G transition in the PS-1 gene, resulting in a glutamic acid (Glu)-to-glycine (Gly) substitution at codon 318 in 2 familial and 2 sporadic AD patients.	Glycine	98-101	presenilin 1	Homo sapiens	40-44
9843516-5	1998	Recombinant DNA techniques have been used to add 14 amino acids, comprising the 10 amino acids of the exonuclease III alpha-helix flanked by a glycine rich region, to DNase I.	Glycine	143-150	deoxyribonuclease 1	Bos taurus	167-174
7858243-4	1994	After hypophysectomy, TRH-Gly and pre-pro-TRH (178-199) concentrations in the hypothalamus increased significantly and TRH concentrations decreased after hypophysectomy.	Glycine	26-29	thyrotropin releasing hormone	Rattus norvegicus	22-25
7858243-5	1994	After the injection of T4, T3, TRH or TSH TRH-Gly and pre-pro-TRH (178-199) concentration in the hypothalamus of hypophysectomized rats decreased significantly, while that of TRH significantly increased.	Glycine	46-49	thyrotropin releasing hormone	Rattus norvegicus	42-45
7858243-5	1994	After the injection of T4, T3, TRH or TSH TRH-Gly and pre-pro-TRH (178-199) concentration in the hypothalamus of hypophysectomized rats decreased significantly, while that of TRH significantly increased.	Glycine	46-49	thyrotropin releasing hormone	Rattus norvegicus	42-45
9786934-3	1998	hnRNP D and nucleolin both contain canonical RNA binding domains (RBDs also called RRMs) and Arg-Gly-Gly (RGG) motifs.	Glycine	97-100	nucleolin	Homo sapiens	12-21
9786934-3	1998	hnRNP D and nucleolin both contain canonical RNA binding domains (RBDs also called RRMs) and Arg-Gly-Gly (RGG) motifs.	Glycine	101-104	nucleolin	Homo sapiens	12-21
8269939-5	1993	These results, together with the fact that big ET-2 and big ET-3 show heterogeneity in the big ET-1 residues His27, Val28, Val29 and Gly34, suggest that the His27-Val-Val-Pro-Tyr-Gly-Leu-Gly34 sequence in the carboxy-terminal region of big ET-1 plays the most important role in selective conversion by endothelin converting enzyme.	Glycine	133-136	endothelin 2	Bos taurus	47-51
9795213-6	1998	The RBP56/hTAFII68, FUS/TLS and EWS proteins comprise a sub-family of RNA binding proteins, which consist of an N-terminal Ser, Gly, Gln and Tyr-rich region, an RNA binding domain, a Cys2/Cys2 zinc finger motif and a C-terminal RGG-containing region.	Glycine	128-131	EWS RNA binding protein 1	Homo sapiens	32-35
9760228-3	1998	In the present study residues 68-86 flanking formylglycine 69 in arylsulfatase A were subjected to an alanine/glycine scanning mutagenesis.	Glycine	51-58	arylsulfatase A	Homo sapiens	65-80
34823857-9	2022	We further measured the inhibitory activity of 5 compounds (rifapentine, velpatasvir, glecaprevir, anidulafungin, and FAD disodium) on SARS-CoV-2 PLpro using Ubiquitin-Rhodamine 110 Gly fluorescent intensity assay.	Glycine	182-185	ORF1a polyprotein;ORF1ab polyprotein	Severe acute respiratory syndrome coronavirus 2	146-151
9759862-6	1998	The C4B12 nucleotide sequence is analogous to C4B1b and C4B3 sequences, except for codon 1076, which is GCC in C4B1b and C4B3 and GGA in C4B12, which is coding for glycine in both cases.	Glycine	164-171	complement C4B (Chido blood group)	Homo sapiens	4-9
34918507-8	2022	In contrast, the receptor binding pattern of the EOs was remarkably consistent and replicated a subclinical affinity pattern corresponding to the inhibitory glycine-alpha-GLRA3 and dopamine-D2 receptors, producing responses dominated by EEG-alpha wave frequencies.	Glycine	157-164	glycine receptor alpha 3	Homo sapiens	171-176
9759862-6	1998	The C4B12 nucleotide sequence is analogous to C4B1b and C4B3 sequences, except for codon 1076, which is GCC in C4B1b and C4B3 and GGA in C4B12, which is coding for glycine in both cases.	Glycine	164-171	complement C4B (Chido blood group)	Homo sapiens	137-142
9751750-8	1998	The purified HLA-DR2/MBP peptide complex readily crystallized by the hanging drop method in 15-18% polyethylene glycol 6000/100 mM glycine, pH 3.5.	Glycine	131-138	myelin basic protein	Homo sapiens	21-24
34819510-2	2021	Here we report a de novo heterozygous missense variant of the PSMB9 proteasome subunit gene in two unrelated Japanese infants resulting in amino acid substitution of the glycine (G) by aspartic acid (D) at position 156 of the encoded protein beta1i.	Glycine	170-177	proteasome 20S subunit beta 9	Homo sapiens	62-67
34819510-2	2021	Here we report a de novo heterozygous missense variant of the PSMB9 proteasome subunit gene in two unrelated Japanese infants resulting in amino acid substitution of the glycine (G) by aspartic acid (D) at position 156 of the encoded protein beta1i.	Glycine	170-177	proteasome 20S subunit beta 9	Homo sapiens	242-248
10087990-4	1998	A nucleotide substitution (424A--&gt;G), which resulted in the Ser142--&gt;Gly amino acid substitution, was the only amino acid polymorphism detected in the open reading frame of the TFR gene in these patients.	Glycine	75-78	transferrin receptor	Homo sapiens	183-186
34834120-1	2021	In our previous paper, we reported that amphiphilic Ir complex-peptide hybrids (IPHs) containing basic peptides such as KK(K)GG (K: lysine, G: glycine) (e.g., ASb-2) exhibited potent anticancer activity against Jurkat cells, with the dead cells showing a strong green emission.	Glycine	143-150	ankyrin repeat and SOCS box containing 2	Homo sapiens	159-164
9685327-0	1998	Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.	Glycine	53-60	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	113-116
34858378-10	2021	The mRNA expression level of jejunal zinc transporter 2 (ZNT2) was higher and that of jejunal Bcl-2-associated X protein (Bax) was lower in the Gly-Zn and zinc lactate groups than in the control group (p<0.05).	Glycine	144-147	solute carrier family 30 member 2	Sus scrofa	37-55
9685327-2	1998	The glycine binding site of this hetero-oligomeric ion channel protein is formed by two distinct extracellular regions, S1 and S2, of the NR1 subunit, whereas the homologous domains of the NR2 subunit mediate glutamate binding.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	138-141
34858378-10	2021	The mRNA expression level of jejunal zinc transporter 2 (ZNT2) was higher and that of jejunal Bcl-2-associated X protein (Bax) was lower in the Gly-Zn and zinc lactate groups than in the control group (p<0.05).	Glycine	144-147	solute carrier family 30 member 2	Sus scrofa	57-61
9685327-8	1998	This indicates that the S1 and S2 domains of the NR1 subunit are sufficient for the formation of a glycine binding site that displays pharmacological properties similar to those of the NMDA receptor in vivo.	Glycine	99-106	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	49-52
9756189-7	1998	The beta2 adrenergic receptors decrease in both number and function at night which is associated with a genetic polymorphism, a glycine 16 substitution.	Glycine	128-135	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	4-9
34718778-6	2022	Biochemical analyses revealed that NFU4 and NFU5 are required for lipoylation of the H proteins of the glycine decarboxylase complex and the E2 subunits of other mitochondrial dehydrogenases, with little impact on Fe-S cluster-containing respiratory complexes or aconitase.	Glycine	103-110	NFU domain protein 5	Arabidopsis thaliana	44-48
9681491-5	1998	Dis (8 microM) decreased the accumulation of TRH accompanied by an equimolar increase in TRH-Gly levels, indicating that pro-TRH biosynthesis persisted.	Glycine	93-96	thyrotropin releasing hormone	Homo sapiens	89-92
34665619-3	2022	PLpro is a promising therapeutic target, albeit challenging owing to featureless P1 and P2 sites recognizing glycine.	Glycine	109-116	ORF1a polyprotein;ORF1ab polyprotein	Severe acute respiratory syndrome coronavirus 2	0-5
1909780-6	1991	The mean serum TRH level at 2 d was 80 +/- 20 pmol/L and fell to the adult range by 21 d. TRH-Gly concentrations were highest in small gut (371 +/- 64 pmol/g) during the neonatal period, falling gradually to adult levels (33 +/- 4.8 pmol/g) by 35 d. Mean hypothalamic TRH-Gly concentrations increased to a peak of 62 +/- 4.5 pmol/g at 13 d, falling thereafter.	Glycine	94-97	thyrotropin releasing hormone	Rattus norvegicus	90-93
1909780-6	1991	The mean serum TRH level at 2 d was 80 +/- 20 pmol/L and fell to the adult range by 21 d. TRH-Gly concentrations were highest in small gut (371 +/- 64 pmol/g) during the neonatal period, falling gradually to adult levels (33 +/- 4.8 pmol/g) by 35 d. Mean hypothalamic TRH-Gly concentrations increased to a peak of 62 +/- 4.5 pmol/g at 13 d, falling thereafter.	Glycine	94-97	thyrotropin releasing hormone	Rattus norvegicus	90-93
1909780-7	1991	High TRH-Gly concentrations (greater than 100 pmol/g) also were observed in pancreas (at d 2), kidney, and pituitary gland (at d 21).	Glycine	9-12	thyrotropin releasing hormone	Rattus norvegicus	5-8
1909780-8	1991	Serum TRH-Gly concentrations were highest (mean 417 +/- 26 pmol/L) on the 2nd postnatal day and gradually decreased to the adult level by 35 d. Changes in the TRH-Gly/TRH ratio were inversely correlated with tissue TRH concentrations in hypothalamus, pancreas, and liver.	Glycine	10-13	thyrotropin releasing hormone	Rattus norvegicus	6-9
9632798-2	1998	hTRN1 interacts with the M9 region of hnRNP A1, a 38-amino-acid domain rich in Gly, Ser, and Asn, and mediates the nuclear import of M9-bearing proteins in vitro.	Glycine	79-82	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	38-46
1675710-3	1991	The replacement of glycine with an aspartic acid residue disrupts the fifth Gly-Xaa-Yaa repeat in the collagen-like domain of each 32 kD MBP peptide chain and probably prevents the formation of the normal triple helix.	Glycine	19-26	myelin basic protein	Homo sapiens	137-140
9627013-7	1998	Reactivity of the Y12 MAb with S10 protein was abolished by deletion of 19 amino acids at the carboxyl-terminus of S10, containing the Gly-Arg-Gly sequence motif shared by Sm-B/B" and Sm-D (D1 and D3).	Glycine	135-138	ribosomal protein S10	Homo sapiens	31-34
1646125-5	1991	The recombinant 3C protease cleaved peptide bond Gln-Gly not only in virus polyprotein, but also in molecules of beta-galactosidase and bovine catalase.	Glycine	53-56	catalase	Bos taurus	143-151
9627013-7	1998	Reactivity of the Y12 MAb with S10 protein was abolished by deletion of 19 amino acids at the carboxyl-terminus of S10, containing the Gly-Arg-Gly sequence motif shared by Sm-B/B" and Sm-D (D1 and D3).	Glycine	135-138	ribosomal protein S10	Homo sapiens	115-118
34416230-8	2021	Characterization of GARs enzymatic functional parameters showed that C. neoformansGARs/AIRs has lower affinity for substrates glycine and PRA compared to the trifunctional metazoan enzyme.	Glycine	126-133	glycyl-tRNA synthetase	Mus musculus	20-24
9627013-7	1998	Reactivity of the Y12 MAb with S10 protein was abolished by deletion of 19 amino acids at the carboxyl-terminus of S10, containing the Gly-Arg-Gly sequence motif shared by Sm-B/B" and Sm-D (D1 and D3).	Glycine	135-138	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	172-178
34416230-8	2021	Characterization of GARs enzymatic functional parameters showed that C. neoformansGARs/AIRs has lower affinity for substrates glycine and PRA compared to the trifunctional metazoan enzyme.	Glycine	126-133	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	Homo sapiens	87-91
9627013-7	1998	Reactivity of the Y12 MAb with S10 protein was abolished by deletion of 19 amino acids at the carboxyl-terminus of S10, containing the Gly-Arg-Gly sequence motif shared by Sm-B/B" and Sm-D (D1 and D3).	Glycine	143-146	ribosomal protein S10	Homo sapiens	31-34
1848781-12	1991	Comparative studies on the binding of A1 versus UP1 to poly[r(epsilon A)] demonstrate that in addition to cooperative protein/protein interactions, the glycine-rich COOH-terminal domain of A1 is also directly involved in protein/nucleic acid interactions.	Glycine	152-159	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	48-51
9627013-7	1998	Reactivity of the Y12 MAb with S10 protein was abolished by deletion of 19 amino acids at the carboxyl-terminus of S10, containing the Gly-Arg-Gly sequence motif shared by Sm-B/B" and Sm-D (D1 and D3).	Glycine	143-146	ribosomal protein S10	Homo sapiens	115-118
9627013-7	1998	Reactivity of the Y12 MAb with S10 protein was abolished by deletion of 19 amino acids at the carboxyl-terminus of S10, containing the Gly-Arg-Gly sequence motif shared by Sm-B/B" and Sm-D (D1 and D3).	Glycine	143-146	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	172-178
34759999-4	2021	On the other hand, among 14 detected mutations in the SARS-CoV-2 S protein that provide advantages to virus for transmission and evasion form treatment, the D614G mutation (substitution of aspartic acid (D) with glycine (G) in codon 614 was particular which could provide the facilitation of the transmission of the virus and virulence.	Glycine	212-219	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	65-66
9627013-10	1998	The carboxyl-terminal Gly-Arg-Gly region of S10 protein is involved in constructing the cross-reactive epitope.	Glycine	22-25	ribosomal protein S10	Homo sapiens	44-47
2006142-1	1991	Covalent linkage of myristate (tetradecanoate; 14:0) to the NH2-terminal glycine residue of the human immunodeficiency virus 1 (HIV-1) 55-kDa gag polyprotein precursor (Pr55gag) is necessary for its proteolytic processing and viral assembly.	Glycine	73-80	Pr55(Gag)	Human immunodeficiency virus 1	169-176
9582306-3	1998	Based on a glycine to serine mutation in the yeast Galpha subunit Gpa1(sst) that prevents deactivation by Sst2 (DiBello, P. R., Garrison, T. R., Apanovitch, D. M., Hoffman, G., Shuey, D. J., Mason, K., Cockett, M. I., and Dohlman, H. G. (1998) J. Biol.	Glycine	11-18	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	66-70
2067980-6	1991	Two amino acid differences were detected at position 1, with Gly in rabbit CGRP instead of Ala in human CGRP-II, and at position 35, with Glu instead of Lys, respectively.	Glycine	61-64	calcitonin-related polypeptide alpha	Rattus norvegicus	75-79
2067980-9	1991	Rabbit CGRP is the only CGRP form which has Gly as the amino terminal amino acid.	Glycine	44-47	calcitonin-related polypeptide alpha	Rattus norvegicus	7-11
2067980-9	1991	Rabbit CGRP is the only CGRP form which has Gly as the amino terminal amino acid.	Glycine	44-47	calcitonin-related polypeptide alpha	Rattus norvegicus	24-28
34519755-4	2021	In this work, concave octahedral Pt-Pd alloy NCs with high-index {hhl} faces were synthesized using glycine as a coordination molecule and polyvinylpyrrolidone as the surfactant and reducing agent.	Glycine	100-107	hes family bHLH transcription factor 1	Homo sapiens	66-69
34646373-0	2021	Pyruvate kinase M2 regulates fibrosis development and progression by controlling glycine auxotrophy in myofibroblasts.	Glycine	81-88	pyruvate kinase, muscle	Mus musculus	0-18
1719898-0	1991	The glycine-extended SP precursor, SP-G, is normally expressed in SP-containing neurons.	Glycine	4-11	surfactant associated 2	Homo sapiens	35-39
9582306-3	1998	Based on a glycine to serine mutation in the yeast Galpha subunit Gpa1(sst) that prevents deactivation by Sst2 (DiBello, P. R., Garrison, T. R., Apanovitch, D. M., Hoffman, G., Shuey, D. J., Mason, K., Cockett, M. I., and Dohlman, H. G. (1998) J. Biol.	Glycine	11-18	GTPase-activating protein SST2	Saccharomyces cerevisiae S288C	106-110
34646373-8	2021	Dimer PKM2 slows the flow rate of glycolysis and channels glycolytic intermediates to de novo glycine synthesis, which facilitates collagen synthesis and secretion in myofibroblasts.	Glycine	94-101	pyruvate kinase, muscle	Mus musculus	6-10
9585570-0	1998	The role of Gly-4 of human cystatin A (stefin A) in the binding of target proteinases.	Glycine	12-15	cystatin A	Homo sapiens	27-37
9585570-1	1998	Characterization by kinetic and equilibrium methods of the interactions of cystatin A Gly-4 mutants with papain, cathepsin B, and cathepsin L.	Glycine	86-89	cystatin A	Homo sapiens	75-85
16839950-3	1991	After start of glycine administration the ratio APE product/APE precursor pool had reached approximately maximal values.	Glycine	15-22	apurinic/apyrimidinic endodeoxyribonuclease 1	Rattus norvegicus	48-51
9585570-2	1998	The importance of the evolutionarily conserved Gly-4 residue for the affinity and kinetics of interaction of cystatin A with several cysteine proteinases was assessed by site-directed mutagenesis.	Glycine	47-50	cystatin A	Homo sapiens	109-119
16839950-3	1991	After start of glycine administration the ratio APE product/APE precursor pool had reached approximately maximal values.	Glycine	15-22	apurinic/apyrimidinic endodeoxyribonuclease 1	Rattus norvegicus	60-63
9546718-2	1998	Bovine UCRP retains the Leu-Arg-Gly-Gly C-terminal sequence of ubiquitin that ligates to and directs degradation of cytosolic proteins.	Glycine	32-35	ubiquitin	Bos taurus	63-72
1909766-5	1991	The present data suggest that TRH-Gly may participate in regulating GH secretion in some patients with acromegaly and that TRH-Gly-induced GH secretion may be due at least in part to TRH-associated mechanisms underlying GH secretion.	Glycine	34-37	thyrotropin releasing hormone	Homo sapiens	30-33
1909766-5	1991	The present data suggest that TRH-Gly may participate in regulating GH secretion in some patients with acromegaly and that TRH-Gly-induced GH secretion may be due at least in part to TRH-associated mechanisms underlying GH secretion.	Glycine	127-130	thyrotropin releasing hormone	Homo sapiens	123-126
1909766-5	1991	The present data suggest that TRH-Gly may participate in regulating GH secretion in some patients with acromegaly and that TRH-Gly-induced GH secretion may be due at least in part to TRH-associated mechanisms underlying GH secretion.	Glycine	127-130	thyrotropin releasing hormone	Homo sapiens	123-126
34116397-0	2021	Targeting of carbonic anhydrase IX-positive cancer cells by glycine-coated superparamagnetic nanoparticles.	Glycine	60-67	carbonic anhydrase 9	Homo sapiens	13-34
9546718-2	1998	Bovine UCRP retains the Leu-Arg-Gly-Gly C-terminal sequence of ubiquitin that ligates to and directs degradation of cytosolic proteins.	Glycine	36-39	ubiquitin	Bos taurus	63-72
9787767-7	1998	Turtle WT1, like those of the alligator, chicken, and Xenopus lacks the proline- and glycine-rich stretches that are present in mammalian WT1.	Glycine	85-92	Wilms tumor 1	Gallus gallus	7-10
1907414-1	1991	Large-scale adaptation of a recently reported glycine precipitation method for the production of factor VIII (FVIII) concentrate is described.	Glycine	46-53	coagulation factor VIII	Homo sapiens	97-108
1907414-1	1991	Large-scale adaptation of a recently reported glycine precipitation method for the production of factor VIII (FVIII) concentrate is described.	Glycine	46-53	coagulation factor VIII	Homo sapiens	110-115
9541598-2	1998	The MMCP-8 mRNA contains an open reading frame of 247 amino acids (aa), divided into a signal sequence of 18 aa followed by a 2-aa activation peptide (Gly-Glu) and a mature protease of 227 aa.	Glycine	151-154	mast cell protease 8	Mus musculus	4-10
2090112-2	1990	Structure-antidepressant activity relationship (examined by the Porsolt test) of MIF and its analogues has been estimated by means of the multivariate statistical analysis, the vicinal spin coupling constants, which determine phi and chi dihedral angles of the second amino acid and phi and dihedral angle of glycine, being selected as structural parameters.	Glycine	309-316	macrophage migration inhibitory factor	Homo sapiens	81-84
34364984-7	2021	We hypothesise that high variance of the diatom C-terminal domain is caused by previously unknown interactions with a CAP-GLY motif of dynactin subunit p150.	Glycine	122-125	chromatin assembly factor 1 subunit A	Homo sapiens	152-156
9489750-2	1998	We found that glutamate, NMDA, glycine, and D-serine were significantly more potent on hNMDAR1A/2D than on hNMDAR1A/2A or hNMDAR1A/2B.	Glycine	31-38	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	122-133
34513771-1	2021	Nonketotic hyperglycinemia (NKH) is a lethal autosomal recessive disease resulting from alterations in glycine metabolism, commonly caused by mutations in glycine decarboxylase (GLDC).	Glycine	103-110	glycine decarboxylase	Homo sapiens	155-176
34513771-1	2021	Nonketotic hyperglycinemia (NKH) is a lethal autosomal recessive disease resulting from alterations in glycine metabolism, commonly caused by mutations in glycine decarboxylase (GLDC).	Glycine	103-110	glycine decarboxylase	Homo sapiens	178-182
34467730-6	2021	CRE-H/M could inhibit the levels of Glu, D-Ser and Gly in the extracellular fluids of ACC(P<0.05), and the levels of Glu in the extracellular fluids of SDH(P<0.05) in SNI rats.	Glycine	51-54	cAMP responsive element modulator	Rattus norvegicus	0-7
2121465-1	1990	TRH (pGlu-His-Pro-NH2) arises from the post-translational processing of a larger precursor peptide containing multiple copies of the TRH progenitor sequence, Gln-His-Pro-Gly.	Glycine	170-173	thyrotropin releasing hormone	Rattus norvegicus	0-3
2121465-1	1990	TRH (pGlu-His-Pro-NH2) arises from the post-translational processing of a larger precursor peptide containing multiple copies of the TRH progenitor sequence, Gln-His-Pro-Gly.	Glycine	170-173	thyrotropin releasing hormone	Rattus norvegicus	133-136
2121465-2	1990	Concentrations of TRH and its precursor peptide (TRH-Gly) were determined in serum and a variety of tissues of the rat using specific RIA systems.	Glycine	53-56	thyrotropin releasing hormone	Rattus norvegicus	49-52
2121465-6	1990	In contrast to the distribution of TRH, relatively higher mean TRH-Gly concentrations were observed in serum (76.5 pg/ml) and in extraneural tissues, including prostate (83.3 pg/mg tissue), spleen (19.0 pg/mg), adrenal (16.2 pg/mg), kidney (13.3 pg/mg), and gastrointestinal tract (6.3-19.8 pg/mg).	Glycine	67-70	thyrotropin releasing hormone	Rattus norvegicus	63-66
2121465-7	1990	Among brain tissues, the TRH-Gly concentration was highest in pituitary gland (13.1 pg/mg).	Glycine	29-32	thyrotropin releasing hormone	Rattus norvegicus	25-28
9490030-8	1998	Glycine at position 53, also in the first transmembrane domain in the human beta3-AR, has been suggested to participate in beta2-/beta3-AR subtype selectivity.	Glycine	0-7	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	123-128
9435301-7	1998	ERK2 activation could be blocked with a combination of anti-alpha4 and -alpha5 antibodies and an arginine-glycine-aspartic acid (RGD) peptide, while the antibodies or peptide used separately failed to block ERK2 activation.	Glycine	106-113	mitogen activated protein kinase 1	Rattus norvegicus	0-4
1982339-0	1990	6,7-Dinitroquinoxaline-2,3-dione and 6-nitro,7-cyanoquinoxaline-2,3-dione antagonize responses mediated by N-methyl-D-aspartate and NMDA-associated glycine recognition sites in vivo: measurements of cerebellar cyclic-GMP.	Glycine	148-155	5'-nucleotidase, cytosolic II	Mus musculus	217-220
2168881-2	1990	We now report that the synthetic peptide Gly-Arg-Gly-Arg-Ser-Ser-Val-Tyr-Ser, which corresponds to the phosphorylated region of Acanthamoeba myosin IC, is a good substrate for myosin I heavy chain kinase: Km = 54 microM, and Vmax = 15 mumols/min.mg.	Glycine	41-44	myosin IA	Homo sapiens	176-196
2168881-2	1990	We now report that the synthetic peptide Gly-Arg-Gly-Arg-Ser-Ser-Val-Tyr-Ser, which corresponds to the phosphorylated region of Acanthamoeba myosin IC, is a good substrate for myosin I heavy chain kinase: Km = 54 microM, and Vmax = 15 mumols/min.mg.	Glycine	49-52	myosin IA	Homo sapiens	176-196
34181727-4	2021	The SMN YG box utilizes a unique variant of the glycine zipper motif to form dimers, but the mechanism of higher-order oligomerization remains unknown.	Glycine	48-55	survival of motor neuron 1, telomeric	Homo sapiens	4-7
34244482-0	2021	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	Glycine	96-103	CREB regulated transcription coactivator 1	Mus musculus	0-6
34244482-0	2021	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	Glycine	96-103	glycine decarboxylase	Homo sapiens	62-83
34244482-1	2021	Glycine decarboxylase (GLDC) is a key enzyme of glycine cleavage system that converts glycine into one-carbon units.	Glycine	48-55	glycine decarboxylase	Homo sapiens	0-21
34244482-1	2021	Glycine decarboxylase (GLDC) is a key enzyme of glycine cleavage system that converts glycine into one-carbon units.	Glycine	48-55	glycine decarboxylase	Homo sapiens	23-27
34244482-1	2021	Glycine decarboxylase (GLDC) is a key enzyme of glycine cleavage system that converts glycine into one-carbon units.	Glycine	86-93	glycine decarboxylase	Homo sapiens	0-21
34244482-1	2021	Glycine decarboxylase (GLDC) is a key enzyme of glycine cleavage system that converts glycine into one-carbon units.	Glycine	86-93	glycine decarboxylase	Homo sapiens	23-27
34201404-6	2021	The consequential changes in extracellular glycine concentration can lead to parallel changes in the activity of NR1/NR2B type NMDA receptors of which glycine is a mandatory agonist, and thereby may reduce neurodegenerative events in the retina.	Glycine	43-50	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	117-121
34201404-6	2021	The consequential changes in extracellular glycine concentration can lead to parallel changes in the activity of NR1/NR2B type NMDA receptors of which glycine is a mandatory agonist, and thereby may reduce neurodegenerative events in the retina.	Glycine	151-158	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	117-121
34201404-9	2021	We have hypothesized that glycine transporter 1 inhibitors and P2Y purinoceptor agonists may have therapeutic importance in neurodegenerative-neuroinflammatory disorders of the retina by decreasing NR1/NR2B NMDA receptor activity and production and release of a series of proinflammatory cytokines from microglial cells.	Glycine	26-33	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	202-206
35508169-4	2022	Mechanistically, loss of PRMT7 resulted in reduced expressions of glycine decarboxylase, leading to the reprograming of glycine metabolism to generate methylglyoxal, which is detrimental to LSCs.	Glycine	120-127	glycine decarboxylase	Homo sapiens	66-87
35212811-9	2022	We also showed that glycine activated mTOR/PPARgamma signaling and identified glycine as a mediator of SHMT2-responsive lipid accumulation in hepatocytes.	Glycine	20-27	peroxisome proliferator activated receptor gamma	Mus musculus	43-52
35212811-10	2022	In conclusion, silencing SHMT2 in hepatocytes ameliorates lipid accumulation via the glycine-mediated mTOR/PPARgamma pathway.	Glycine	85-92	peroxisome proliferator activated receptor gamma	Mus musculus	107-116
35077997-1	2022	Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S-S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively.	Glycine	98-101	prolyl 4-hydroxylase subunit beta	Homo sapiens	0-27
35077997-1	2022	Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S-S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively.	Glycine	98-101	prolyl 4-hydroxylase subunit beta	Homo sapiens	29-32
35077997-1	2022	Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S-S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively.	Glycine	98-101	prolyl 4-hydroxylase subunit beta	Homo sapiens	223-226
35194995-2	2022	In response, we studied the effects of glycine as a surrogate zwitterion, ion, and osmolyte on the electrostatic forces between negatively charged mica-mica and silica-silica interfaces.	Glycine	39-46	MHC class I polypeptide-related sequence A	Homo sapiens	147-151
35194995-2	2022	In response, we studied the effects of glycine as a surrogate zwitterion, ion, and osmolyte on the electrostatic forces between negatively charged mica-mica and silica-silica interfaces.	Glycine	39-46	MHC class I polypeptide-related sequence A	Homo sapiens	152-156
35045283-4	2022	Low PSAT1 prevents de novo serine biosynthesis and sensitizes luminal breast cancer cells to serine and glycine starvation in vitro and in vivo.	Glycine	104-111	phosphoserine aminotransferase 1	Homo sapiens	4-9
35162963-5	2022	In the WT mice, the proliferative activity in the HA binding peptide-OPN mimic peptide fusion coated group was significantly higher than that in the control group from day 3 to week 1, and the rates of OPN deposition and direct osteogenesis around the implant surface significantly increased in the recombinant-mouse-OPN (rOPN) group compared to the Gly-Arg-Gly-Asp-Ser peptide group in week 2.	Glycine	350-353	secreted phosphoprotein 1	Mus musculus	69-72
2207061-7	1990	On the basis of these results, we propose that peptide C-terminal amidation in neurointermediate pituitary is a two-step process, with PAM first catalyzing the conversion of a glycine-extended peptide to the alpha-hydroxyglycine derivative, which is in turn converted to the final amide product by HGAD.	Glycine	176-183	peptidylglycine alpha-amidating monooxygenase	Bos taurus	135-138
2369430-5	1990	Relative risk was also associated with DR1.1, the common white DR1 (Dw1) type, which has a third hypervariable region amino acid sequence similar to some forms of DR4 and has glycine at position 86.	Glycine	175-182	down-regulator of transcription 1	Homo sapiens	39-42
2141206-2	1990	The penultimate Gly in nsP1 or nsP2 or both was substituted by Ala, Val, or Glu, and processing was studied in vitro.	Glycine	16-19	reticulon 2	Homo sapiens	31-35
2117583-2	1990	TRH derives from a 242-amino acid precursor protein, prepro-TRH, with six repetitive sequences of -Lys-Arg-Gln-His-Pro-Gly-Lys/Arg)-Arg- connected by hydrophobic linking sequences.	Glycine	119-122	thyrotropin releasing hormone	Homo sapiens	0-3
2117583-3	1990	Antibodies to TRH-Gly (pGlu-His-Pro-Gly), a final precursor for TRH formation, were used to detect this tetrapeptide as well as other prepro-TRH fragments which cross-react with these antibodies.	Glycine	18-21	thyrotropin releasing hormone	Homo sapiens	14-17
2117583-3	1990	Antibodies to TRH-Gly (pGlu-His-Pro-Gly), a final precursor for TRH formation, were used to detect this tetrapeptide as well as other prepro-TRH fragments which cross-react with these antibodies.	Glycine	18-21	thyrotropin releasing hormone	Homo sapiens	64-67
2117583-3	1990	Antibodies to TRH-Gly (pGlu-His-Pro-Gly), a final precursor for TRH formation, were used to detect this tetrapeptide as well as other prepro-TRH fragments which cross-react with these antibodies.	Glycine	18-21	thyrotropin releasing hormone	Homo sapiens	64-67
2117583-5	1990	The TRH-Gly immunoreactivity in semen increased significantly during in-vitro incubation at 0 or 37 degrees C, to a peak value at 5 h, followed by an exponential decline, with t 1/2 equal to 11 h at 37 degrees C. At 60 degrees C, however, the TRH-Gly immunoreactivity rose continuously, attaining, after 20 h, a level 2.2 times that at the start of the incubation (P less than 0.001).	Glycine	8-11	thyrotropin releasing hormone	Homo sapiens	4-7
2117583-5	1990	The TRH-Gly immunoreactivity in semen increased significantly during in-vitro incubation at 0 or 37 degrees C, to a peak value at 5 h, followed by an exponential decline, with t 1/2 equal to 11 h at 37 degrees C. At 60 degrees C, however, the TRH-Gly immunoreactivity rose continuously, attaining, after 20 h, a level 2.2 times that at the start of the incubation (P less than 0.001).	Glycine	247-250	thyrotropin releasing hormone	Homo sapiens	4-7
2117583-7	1990	A minor, TRH-Gly immunoreactive peak increased 50-fold (P less than 0.001) during 20 h at 60 degrees C. This material co-eluted with Arg-Gln-His-Pro-Gly which is formed by enzymic cleavage of the paired basic residues flanking this sequence in prepro-TRH.	Glycine	13-16	thyrotropin releasing hormone	Homo sapiens	9-12
2117583-7	1990	A minor, TRH-Gly immunoreactive peak increased 50-fold (P less than 0.001) during 20 h at 60 degrees C. This material co-eluted with Arg-Gln-His-Pro-Gly which is formed by enzymic cleavage of the paired basic residues flanking this sequence in prepro-TRH.	Glycine	13-16	thyrotropin releasing hormone	Homo sapiens	251-254
2117583-7	1990	A minor, TRH-Gly immunoreactive peak increased 50-fold (P less than 0.001) during 20 h at 60 degrees C. This material co-eluted with Arg-Gln-His-Pro-Gly which is formed by enzymic cleavage of the paired basic residues flanking this sequence in prepro-TRH.	Glycine	149-152	thyrotropin releasing hormone	Homo sapiens	9-12
2117583-8	1990	When synthetic Arg-Gln-His-Pro-Gly was incubated with fresh semen at 60 degrees C a rapid conversion of most of this peptide to Glu-His-Pro-Gly, Gln-His-Pro-Gly and TRH-Gly occurred within 30 min.	Glycine	31-34	thyrotropin releasing hormone	Homo sapiens	165-168
2199334-7	1990	In each mutant, a single bp substitution, causing the replacement of Gly residues by either Asp (cdc17-1, cdc17-2) or Glu (hpr3) in yeast DNA polymerase I is responsible for the ts phenotype.	Glycine	69-72	DNA-directed DNA polymerase alpha catalytic subunit POL1	Saccharomyces cerevisiae S288C	123-127
2115563-5	1990	Concentrations of TRH and TRH-Gly in the posterior pituitary, on the other hand, which derive from neurones of hypothalamic origin, increased significantly with castration and were returned to the normal range by testosterone replacement.	Glycine	30-33	thyrotropin releasing hormone	Rattus norvegicus	26-29
1970117-8	1990	The locations of cysteine residues flanking the Gly-X-Y repeat regions of rol-6 and sqt-1 are identical, but differ from those in the other collagens.	Glycine	48-51	Cuticle collagen rol-6	Caenorhabditis elegans	74-79
2324102-7	1990	Furthermore, (iv) the transmembrane domain is 96% identical, as the only change in human syndecan was an alteration of an alanine residue to glycine; and finally, (v) the cytoplasmic domain is 100% identical, including 3 identically located tyrosine residues.	Glycine	141-148	syndecan 1	Homo sapiens	89-97
1693271-5	1990	The amino acid composition of PAPP-A differed most significantly from alpha 2M, in the content of glutamate, glycine and lysine.	Glycine	109-116	pappalysin 1	Homo sapiens	30-36
2153207-8	1990	No upper size limitation or specificity has been found at this position, yet similar replacements at the P3" position, which is occupied naturally by a glycine residue, gave weaker inhibitors: (EtO)(OK)P(O)-Ile-Tyr(OBzl)-PheOK (57) had a Ki of 120 microM.	Glycine	152-159	RUNX1 partner transcriptional co-repressor 1	Homo sapiens	194-197
33794243-3	2021	Mutations in the human SLC6A5 gene encoding the neuronal glycine transporter GlyT2 may disrupt the inhibitory glycinergic neurotransmission and cause a presynaptic form of the disease.	Glycine	57-64	solute carrier family 6 member 5	Homo sapiens	23-29
33794243-3	2021	Mutations in the human SLC6A5 gene encoding the neuronal glycine transporter GlyT2 may disrupt the inhibitory glycinergic neurotransmission and cause a presynaptic form of the disease.	Glycine	57-64	solute carrier family 6 member 5	Homo sapiens	77-82
33772775-4	2021	Mechanism studies revealed that glycine could decrease urine oxalate through downregulating Slc26a6 expression, whereas increase urine citrate via inhibiting Nadc1 expression.	Glycine	32-39	solute carrier family 13 member 2	Homo sapiens	158-163
33772775-5	2021	Moreover, glycine decreased the protein expression of both Slc26a6 and Nadc1 via increasing the expression of miRNA-411-3p, which directly bound to the 3"-untranslated regions of Slc26a6 and Nadc1 messenger RNAs, in vitro and in vivo.	Glycine	10-17	solute carrier family 13 member 2	Homo sapiens	71-76
33772775-5	2021	Moreover, glycine decreased the protein expression of both Slc26a6 and Nadc1 via increasing the expression of miRNA-411-3p, which directly bound to the 3"-untranslated regions of Slc26a6 and Nadc1 messenger RNAs, in vitro and in vivo.	Glycine	10-17	solute carrier family 13 member 2	Homo sapiens	191-196
33765249-0	2022	Calcium-Dependent Regulation of the Neuronal Glycine Transporter GlyT2 by M2 Muscarinic Acetylcholine Receptors.	Glycine	45-52	solute carrier family 6 member 5	Homo sapiens	65-70
33765249-1	2022	The neuronal glycine transporter GlyT2 modulates inhibitory glycinergic neurotransmission and plays a key role in regulating nociceptive signal progression.	Glycine	13-20	solute carrier family 6 member 5	Homo sapiens	33-38
33807656-3	2021	All six beta-type connexins expressed in human epidermis (Cx26, Cx30, Cx30.3, Cx31, Cx31.1 and Cx32) contain a glycine at position 12 (G12).	Glycine	111-118	gap junction protein beta 6	Homo sapiens	64-68
33233834-14	2020	It is noteworthy that since the serine 3-carbon is unlabeled in these experiments, the isotopic enrichments in dT + 1, Ser + 2, dA + 3, dG + 3, and Met + 1 solely come from the 2-carbon of glycine/serine recycled from GCS, re-enters the cytosolic 1C metabolism as formate, and then being used for cytosolic syntheses of serine, dTMP, purine (M + 3) and methionine.	Glycine	189-196	jagged canonical Notch ligand 2	Homo sapiens	119-142
34668105-10	2022	The AS2/LOB domain is characterized by three subdomains, the zinc finger (ZF) motif, the internally conserved-glycine containing (ICG) region, and the leucine-zipper-like (LZL) region.	Glycine	110-117	Lateral organ boundaries (LOB) domain family protein	Arabidopsis thaliana	4-7
34266921-4	2021	We present an example of stimulus induced hyperekplexia captured on video EEG in a 7-week-old girl with compound heterozygous variants in the presynaptic glycine transporter gene SLC6A5.	Glycine	154-161	solute carrier family 6 member 5	Homo sapiens	179-185
34418357-1	2021	The enzymes glycine amidinotransferase, mitochondrial (GATM also known as AGAT) and guanidinoacetate N-methyltransferase (GAMT) function together to synthesize creatine from arginine, glycine, and S-Adenosyl methionine.	Glycine	12-19	guanidinoacetate N-methyltransferase	Homo sapiens	122-126
34418357-1	2021	The enzymes glycine amidinotransferase, mitochondrial (GATM also known as AGAT) and guanidinoacetate N-methyltransferase (GAMT) function together to synthesize creatine from arginine, glycine, and S-Adenosyl methionine.	Glycine	184-191	guanidinoacetate N-methyltransferase	Homo sapiens	84-120
34418357-1	2021	The enzymes glycine amidinotransferase, mitochondrial (GATM also known as AGAT) and guanidinoacetate N-methyltransferase (GAMT) function together to synthesize creatine from arginine, glycine, and S-Adenosyl methionine.	Glycine	184-191	guanidinoacetate N-methyltransferase	Homo sapiens	122-126
34298585-2	2021	Mutations in the mitochondrial glycine carrier SLC25A38 cause the most common recessive form of CSA.	Glycine	31-38	solute carrier family 25 member 38	Homo sapiens	47-55
34720086-3	2021	Here we show that PHGDH was monoubiquitinated by cullin 4A-based E3 ligase complex at lysine 146 in colorectal cancer (CRC) cells, which enhanced PHGDH activity by recruiting a chaperone protein, DnaJ homolog subfamily A member 1, to promote its tetrameric formation, thereby increasing the levels of serine, glycine, and S-adenosylmethionine (SAM).	Glycine	309-316	phosphoglycerate dehydrogenase	Homo sapiens	18-23
34720086-3	2021	Here we show that PHGDH was monoubiquitinated by cullin 4A-based E3 ligase complex at lysine 146 in colorectal cancer (CRC) cells, which enhanced PHGDH activity by recruiting a chaperone protein, DnaJ homolog subfamily A member 1, to promote its tetrameric formation, thereby increasing the levels of serine, glycine, and S-adenosylmethionine (SAM).	Glycine	309-316	phosphoglycerate dehydrogenase	Homo sapiens	146-151
34744627-6	2021	Additionally, using electrophysiological recordings in dissociated accumbal neurons, we found that the glycine current density increased in Glra3 -/- mice and the GlyRs were less affected by ethanol and picrotoxin.	Glycine	103-110	glycine receptor, alpha 3 subunit	Mus musculus	140-145
34682758-4	2021	In our cohort, we found that graft from a donor with at least one MICA allele containing glycine at position 14 (MICA-14Gly) is significantly associated with deterioration of a patient"s overall survival (OS) (p < 0.05).	Glycine	89-96	MHC class I polypeptide-related sequence A	Homo sapiens	66-70
34682758-4	2021	In our cohort, we found that graft from a donor with at least one MICA allele containing glycine at position 14 (MICA-14Gly) is significantly associated with deterioration of a patient"s overall survival (OS) (p < 0.05).	Glycine	89-96	MHC class I polypeptide-related sequence A	Homo sapiens	113-117
34551291-6	2021	As a result, loss of ATF3 expression impairs serine biosynthesis and the growth of cancer cells in the serine-deprived medium or in mice fed with a serine/glycine-free diet.	Glycine	155-162	activating transcription factor 3	Mus musculus	21-25
34576163-2	2021	In our previous studies, we reported the robust neuroprotective effects of the icosamer OPN peptide OPNpt20, containing arginine-glycine-aspartic acid (RGD) and serine-leucine-alanine-tyrosine (SLAY) motifs, in an animal model of transient focal ischemia and demonstrated that its anti-inflammatory, pro-angiogenic, and phagocytosis inducing functions are responsible for the neuroprotective effects.	Glycine	129-136	secreted phosphoprotein 1	Rattus norvegicus	88-91
34539595-3	2021	We show that these tRFs originate from select tRNAs (GCC and CAC for glycine, CTT and AAC for Valine, and CCC and TTT for Lysine).	Glycine	69-76	guanylate cyclase 2C	Homo sapiens	53-56
34264571-0	2021	A Glra3 phospho-deficient mouse mutant establishes the critical role of PKA-dependent phosphorylation and inhibition of glycine receptors in spinal inflammatory hyperalgesia.	Glycine	120-127	glycine receptor, alpha 3 subunit	Mus musculus	2-7
34197627-3	2021	cAMP stimulation of differentiated adipocytes led to elevated uptake of serine, cysteine, and glycine, in parallel with increased oxygen consumption, augmented UCP1-dependent proton leak, increased creatine-driven substrate cycle coupled respiration, and upregulation of thermogenesis marker genes and several respiratory complex subunits; these outcomes were impeded in the presence of the specific ASC-1 inhibitor, BMS-466442.	Glycine	94-101	solute carrier family 7 member 10	Homo sapiens	400-405
34197627-4	2021	Our data suggest that ASC-1-dependent consumption of serine, cysteine, and glycine is required for efficient thermogenic stimulation of human adipocytes.	Glycine	75-82	solute carrier family 7 member 10	Homo sapiens	22-27
34095107-10	2021	Interestingly, PREP disruption inhibited p-ERK and p-p65 and reduced the levels of proinflammatory cytokines in response to endotoxin and proline-glycine-proline, which guided macrophage/neutrophil infiltration in mice fed a HFD for 24 weeks.	Glycine	146-153	prolyl endopeptidase	Mus musculus	15-19
34234394-4	2021	Our phylogeny analysis of 1947 sequences of S proteins indicated there is a change in amino acid (aa) from aspartate (Group-A) to glycine (Group-B) at position 614, near the receptor- binding domain (RBD; aa positions 331-524).	Glycine	130-137	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	44-45
9473659-3	1998	This study examined CMRglu and CBF changes caused by antagonism of glycine at the NMDA receptor recognition site.	Glycine	67-74	CCAAT/enhancer binding protein zeta	Rattus norvegicus	31-34
9541227-8	1998	Dentin sialoprotein (DSP), found only in dentin, is a 53 kDa glycoprotein rich in aspartic acid, serine, glutamic acid and glycine.	Glycine	123-130	dentin sialophosphoprotein	Homo sapiens	0-19
9533650-1	1998	The relaxant effect of a novel VIP analog, [Arg15,20,21Leu17]-VIP-Gly-Lys-Arg-NH2 was compared with that of the original VIP in the same guinea pig trachea precontracted by carbachol in vitro.	Glycine	66-69	VIP peptides	Cavia porcellus	31-34
34991220-5	2022	Results: Our results indicated that glycine alleviated diquat induced morphological hepatic injury, decreased the activities of plasma alanine aminotransferase, aspartate aminotransferase and glutamyl transpeptidase in the piglets under diquat challenge, and increased total antioxidant capacity and antioxidative enzyme activity significantly.	Glycine	36-43	glutamic--pyruvic transaminase	Homo sapiens	135-159
9533650-1	1998	The relaxant effect of a novel VIP analog, [Arg15,20,21Leu17]-VIP-Gly-Lys-Arg-NH2 was compared with that of the original VIP in the same guinea pig trachea precontracted by carbachol in vitro.	Glycine	66-69	VIP peptides	Cavia porcellus	62-65
9533650-1	1998	The relaxant effect of a novel VIP analog, [Arg15,20,21Leu17]-VIP-Gly-Lys-Arg-NH2 was compared with that of the original VIP in the same guinea pig trachea precontracted by carbachol in vitro.	Glycine	66-69	VIP peptides	Cavia porcellus	62-65
9405346-1	1997	The threonine-glycine (Thr-Gly) encoding repeat within the clock gene period of Drosophila melanogaster is polymorphic in length.	Glycine	27-30	Clock	Drosophila melanogaster	59-64
35554494-4	2022	Genetic complementation experiments in budding yeast demonstrate that the conserved aspartate or its analogous asparagine (N) residue in yeast TAF7 is essential for cell viability and thus its mutation to glycine is lethal.	Glycine	205-212	TATA-binding protein-associated factor TAF7	Saccharomyces cerevisiae S288C	143-147
9393748-3	1997	Galectin-3 contains the NWGR amino acid sequence highly conserved in the BH1 domain of the bcl-2 gene family, and a substitution of glycine to alanine in this motif abrogated its antiapoptotic activity.	Glycine	132-139	galectin 3	Homo sapiens	0-10
9375665-4	1997	Brief application of an NMDA/glycine solution to cells markedly increased intracellular calcium in cells transfected with NR1/NR2A, NR1/NR2B, or NR1/NR2A/NR2B as measured by fura-2 calcium imaging.	Glycine	29-36	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	154-158
35628160-5	2022	By using ELISA, we evaluated MS-induced changes in the NMDAR subunits (GluN1, GluN2A, GluN2B) expression, especially in the glycine-binding subunit, GluN1, in the prefrontal cortex (PFC) and ventral striatum (vSTR) of male/female rats.	Glycine	124-131	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	149-154
9353268-8	1997	The interaction between sentrin and Ubc9 required the ubiquitin domain and the C-terminal Gly-Gly residues of sentrin.	Glycine	90-93	small ubiquitin like modifier 1	Homo sapiens	24-31
35563125-2	2022	AGAT also catalyzes the formation of guanidinoacetate (GAA) and Orn from Arg and glycine (Gly): Arg + Gly   GAA + Orn; equilibrium constant KGAA.	Glycine	81-88	glycine amidinotransferase	Rattus norvegicus	0-4
35563125-2	2022	AGAT also catalyzes the formation of guanidinoacetate (GAA) and Orn from Arg and glycine (Gly): Arg + Gly   GAA + Orn; equilibrium constant KGAA.	Glycine	90-93	glycine amidinotransferase	Rattus norvegicus	0-4
35563125-2	2022	AGAT also catalyzes the formation of guanidinoacetate (GAA) and Orn from Arg and glycine (Gly): Arg + Gly   GAA + Orn; equilibrium constant KGAA.	Glycine	102-105	glycine amidinotransferase	Rattus norvegicus	0-4
9353268-8	1997	The interaction between sentrin and Ubc9 required the ubiquitin domain and the C-terminal Gly-Gly residues of sentrin.	Glycine	90-93	ubiquitin conjugating enzyme E2 I	Homo sapiens	36-40
9353268-8	1997	The interaction between sentrin and Ubc9 required the ubiquitin domain and the C-terminal Gly-Gly residues of sentrin.	Glycine	90-93	small ubiquitin like modifier 1	Homo sapiens	110-117
9353268-8	1997	The interaction between sentrin and Ubc9 required the ubiquitin domain and the C-terminal Gly-Gly residues of sentrin.	Glycine	94-97	small ubiquitin like modifier 1	Homo sapiens	24-31
35181460-9	2022	GLP-1 delivered dose was improved by the addition of SFD 10% glycine-mannitol carrier to the DPI formulation (32.88% +- 7.00% -> 45.92% +- 5.84%).	Glycine	61-68	glucagon like peptide 1 receptor	Homo sapiens	0-5
9353268-8	1997	The interaction between sentrin and Ubc9 required the ubiquitin domain and the C-terminal Gly-Gly residues of sentrin.	Glycine	94-97	ubiquitin conjugating enzyme E2 I	Homo sapiens	36-40
9353268-8	1997	The interaction between sentrin and Ubc9 required the ubiquitin domain and the C-terminal Gly-Gly residues of sentrin.	Glycine	94-97	small ubiquitin like modifier 1	Homo sapiens	110-117
9346936-3	1997	Preparation of recombinant rat Bcl-xL yielded two forms, one deamidated at -Asn-Gly- sequences to produce isoaspartates and the other not deamidated.	Glycine	80-83	Bcl2-like 1	Rattus norvegicus	31-37
35346007-2	2022	D-Serine is implicated in the pathophysiological progression of AD and it is produced by the enzyme serine racemase (SR) in the brain and functions as an endogenous co-agonist at the glycine-binding site of N-methyl-D-aspartate receptor (NMDAR).	Glycine	183-190	serine racemase	Homo sapiens	100-115
9399582-5	1997	The order of Kcat/Km values of AAP at optimal pH (pH 7.5) was Ala- &gt; Lys-Ala- &gt; or = Met- &gt; Leu- &gt; Phe- &gt; Arg- &gt; or = Arg-Arg- &gt; Lys- &gt; Gly-MCAs.	Glycine	160-163	alanyl aminopeptidase, membrane	Homo sapiens	31-34
35371624-4	2022	Each Gly and Bet are replaced, respectively, by ~3 and ~5 water molecules, with the highest rates of depletion being found for Gly around Bet and Gly around Gly.	Glycine	127-130	delta/notch like EGF repeat containing	Homo sapiens	13-16
35371624-4	2022	Each Gly and Bet are replaced, respectively, by ~3 and ~5 water molecules, with the highest rates of depletion being found for Gly around Bet and Gly around Gly.	Glycine	127-130	delta/notch like EGF repeat containing	Homo sapiens	138-141
35371624-4	2022	Each Gly and Bet are replaced, respectively, by ~3 and ~5 water molecules, with the highest rates of depletion being found for Gly around Bet and Gly around Gly.	Glycine	146-149	delta/notch like EGF repeat containing	Homo sapiens	13-16
9305960-0	1997	Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.	Glycine	16-23	cytochrome P450 2B1	Rattus norvegicus	108-127
35150347-9	2022	GEO data revealed that gamma-tocotrienol (g-T3), NSC319726, and Casiopeina Cas-II-gly may reduce the expression of, NDUFAF1, CCNB1, DKK1 genes, respectively (P < 0.01).	Glycine	82-85	dickkopf WNT signaling pathway inhibitor 1	Homo sapiens	132-136
9331262-7	1997	Sequence analysis of the RPGR gene identified a single base pair change, a G--&gt;T transversion, that converts codon 52 GGA (Gly) to TGA (stop codon); the mutation segregates with the disease.	Glycine	126-129	T-box transcription factor 1	Homo sapiens	134-137
35054318-5	2022	The erythroid-specific ALAS2 catalyses the synthesis of delta-aminolevulinic acid (ALA), from the union of glycine and succinyl-coenzyme A, in the first step of the pathway in the erythron.	Glycine	107-114	5'-aminolevulinate synthase 2	Homo sapiens	23-28
9350978-1	1997	Insulin was purified from an extract of the pancreas of the Burmese python, Python molurus (Squamata:Serpentes) and its primary structure established as: A Chain: Gly-Ile-Val-Glu-Gln-Cys-Cys-Glu-Asn-Thr10-Cys-Ser-Leu-Tyr-Glu-Leu- Glu-Asn-Tyr-Cys20-Asn.	Glycine	163-166	insulin	Python bivittatus	0-7
9300641-3	1997	As many extracellular matrix (ECM) molecules contain the conserved amino acid sequence arg-gly-asp-ser (RGDS) at the integrin recognition site, integrin-ECM binding can be disrupted using RGDS peptides.	Glycine	91-94	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	104-108
9300641-3	1997	As many extracellular matrix (ECM) molecules contain the conserved amino acid sequence arg-gly-asp-ser (RGDS) at the integrin recognition site, integrin-ECM binding can be disrupted using RGDS peptides.	Glycine	91-94	ral guanine nucleotide dissociation stimulator	Rattus norvegicus	188-192
9162015-3	1997	Because sentrin possesses the conserved Gly-Gly residues near the C terminus, it is likely that these additional bands represent conjugation of sentrin to other proteins in a manner that is similar to the ubiquitination pathway.	Glycine	40-43	small ubiquitin like modifier 1	Homo sapiens	8-15
9162015-3	1997	Because sentrin possesses the conserved Gly-Gly residues near the C terminus, it is likely that these additional bands represent conjugation of sentrin to other proteins in a manner that is similar to the ubiquitination pathway.	Glycine	44-47	small ubiquitin like modifier 1	Homo sapiens	8-15
9162015-4	1997	Transient expression of hemagglutinin epitope-tagged sentrin mutants in COS cells demonstrated that the sentrin C terminus is cleaved, which allows it to be conjugated to other proteins via the conserved C-terminal Gly residue.	Glycine	215-218	small ubiquitin like modifier 1	Homo sapiens	53-60
9158070-3	1997	The levels of PS4 were highly correlated with the corresponding TRH (p-Glu-His-Pro-NH2) and TRH-Gly (p-Glu-His-Pro-Gly) levels in hippocampus, amygdala, and pyriform cortex, consistent with the prepro-TRH source of all of these peptides.	Glycine	96-99	thyrotropin releasing hormone	Rattus norvegicus	92-95
9158070-3	1997	The levels of PS4 were highly correlated with the corresponding TRH (p-Glu-His-Pro-NH2) and TRH-Gly (p-Glu-His-Pro-Gly) levels in hippocampus, amygdala, and pyriform cortex, consistent with the prepro-TRH source of all of these peptides.	Glycine	96-99	thyrotropin releasing hormone	Rattus norvegicus	92-95
9092805-0	1997	Functional transitions in myosin: role of highly conserved Gly and Glu residues in the active site.	Glycine	59-62	myosin, heavy chain 15	Gallus gallus	26-32
9194172-5	1997	The chimera that contained a glycine in lieu of the aspartic acid present in native onconase (position 26 in the chimera) exhibited enzymatic activity more characteristic of EDN than native onconase and was considerably more active with respect to both RNase activity and cellular cytotoxicity than recombinant onconase.	Glycine	29-36	ribonuclease A family member 2	Homo sapiens	174-177
9062131-7	1997	N-Terminal sequencing of the M(r) 45,000 polypeptide in the purified preparation of aminopeptidase A revealed that it resulted from cleavage at the Asn-602-Gly-603 bond by an endogenous protease.	Glycine	156-159	glutamyl aminopeptidase	Homo sapiens	84-100
9099944-1	1997	Peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes the amidation of glycine-extended peptides in neuroendocrine cells.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Mus musculus	47-50
8990170-4	1997	Using a tissue culture transfection assay, we demonstrate that the Gly residues within the Gly-rich domain, the ribonucleoprotein motifs within the RNA recognition motif RNA binding domain, and the SR domain are required for regulation of dsx splicing by RBP1 in vivo.	Glycine	67-70	doublesex	Drosophila melanogaster	239-242
8990170-4	1997	Using a tissue culture transfection assay, we demonstrate that the Gly residues within the Gly-rich domain, the ribonucleoprotein motifs within the RNA recognition motif RNA binding domain, and the SR domain are required for regulation of dsx splicing by RBP1 in vivo.	Glycine	91-94	doublesex	Drosophila melanogaster	239-242
9151450-7	1997	In mammals, the highest homology was with 50-kDa nucleolin fragments containing the RNA-binding motifs and the glycine-arginine-rich (GAR) domain.	Glycine	111-118	nucleolin	Homo sapiens	49-58
8977155-0	1996	Hypothesis: glucagon receptor glycine to serine missense mutation contributes to one in 20 cases of essential hypertension.	Glycine	30-37	glucagon receptor	Homo sapiens	12-29
8942988-7	1996	These studies demonstrated that Gly-63 is important for the high activity of bovine and rabbit CA IVs, and they showed that the low activity of murine CA IV could be improved by the Gln-63--&gt;Gly substitution.	Glycine	32-35	carbonic anhydrase 4	Mus musculus	95-100
8942988-7	1996	These studies demonstrated that Gly-63 is important for the high activity of bovine and rabbit CA IVs, and they showed that the low activity of murine CA IV could be improved by the Gln-63--&gt;Gly substitution.	Glycine	194-197	carbonic anhydrase 4	Mus musculus	95-100
8950090-5	1996	The onset of inhibition by 100 microM Cu2+ of responses to 2 microM glutamate acting at NMDA receptors was significantly faster than NMDA receptor deactivation evoked by a sudden decrease in the concentration of glycine or glutamate, or of both agonists.	Glycine	212-219	immunoglobulin kappa variable 1-35	Mus musculus	38-41
8890223-4	1996	The results demonstrate that HlyA binding to target cells is independent of several structural components of the active toxin, including the N-terminal hydrophobic region, the glycine-rich repeat region, and the HlyC-dependent acylation of HlyA.	Glycine	176-183	hemolysin transport protein	Escherichia coli	29-33
8772735-2	1996	We therefore scanned the amylin gene for mutations in 294 Japanese NIDDM patients by single-strand conformational polymorphism, and we found a single heterozygous missense mutation (Ser--&gt;Gly at position 20: S20G mutation) in 12 NIDDM patients (frequency 4.1%).	Glycine	191-194	islet amyloid polypeptide	Homo sapiens	25-31
8812870-6	1996	Purified HIV-2 Tat proteins in which the glutamic acid residue at position 77 was changed to either glycine or glutamine transactivated the HIV-1 LTR more efficiently than wild-type Tat-2, providing additional evidence that the net charge of this region may be responsible for nonreciprocal transactivation between Tat-1 and Tat-2.	Glycine	100-107	tyrosine aminotransferase	Homo sapiens	15-18
8702537-7	1996	Mutation of the N-terminal glycine results in a nonmyristoylated form of MARCKS which does not bind membranes and is poorly phosphorylated.	Glycine	27-34	myristoylated alanine rich protein kinase C substrate	Homo sapiens	73-79
8769411-11	1996	Furthermore, through the use of the two-hybrid system, it was demonstrated that both the PAS10 gene product (Pas10p) and the human PTS1 receptor can interact with the COOH-terminal region of human catalase, but that this interaction is abolished by substitutions at the penultimate residue (asparagine-to- aspartate) and at the fourth residue from the COOH terminus (lysine-to-glycine) which abolish PTS functionality.	Glycine	377-384	peroxisomal biogenesis factor 5	Homo sapiens	131-144
9275438-5	1996	RESULTS: The group with PIH showed the following changes: amino acidemia and ammonemia; high aromatic amino acidemia; high threonine, arginine, glycine, cystine and glutamic acidemia.	Glycine	144-151	pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included)	Homo sapiens	24-27
8760119-4	1996	Extraction of glycine-extended gastrin-17 was measured in the kidney (36%), hindlimb (31%, P &lt; 0.001), head (26%), and the gut (16%, P &lt; 0.01), but not in the liver or the lungs.	Glycine	14-21	gastrin	Sus scrofa	31-38
8760119-5	1996	Glycine-extended gastrin-17 was not processed to amidated gastrin during infusion.	Glycine	0-7	gastrin	Sus scrofa	17-24
8760119-6	1996	The half-life, metabolic clearance rate, and apparent volume of distribution for amidated gastrin-17 were 3.5 +/- 0.4 min, 15.5 +/- 1.1 ml.kg-1.min-1, and 76.5 +/- 9.9 ml/kg, respectively, and for glycine-extended gastrin-17 were 4.3 +/- 0.6 min, 17.4 +/- 0.9 ml.kg-1.min-1, and 104.7 +/- 11.9 ml/kg, respectively.	Glycine	197-204	gastrin	Sus scrofa	90-97
8760119-7	1996	We conclude that extraction of amidated and glycine-extended gastrin-17 varies in the vascular beds, with elimination mainly confined to nonorgan tissues and the kidneys.	Glycine	44-51	gastrin	Sus scrofa	61-68
8676373-0	1996	hnRNP A1 selectively interacts through its Gly-rich domain with different RNA-binding proteins.	Glycine	43-46	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	0-8
8635644-3	1996	We have previously reported that a single heterozygous missense mutation in exon 2 of the glucagon receptor gene, which changes a glycine to a serine (Gly40Ser), is associated with NIDDM in a French population.	Glycine	130-137	glucagon receptor	Homo sapiens	90-107
8632186-3	1996	The polyamine site agonist spermine showed differential modulation of glutamate- and glycine-stimulated 45Ca2+ influx for recombinant NMDA receptors, inhibiting and stimulating 45Ca2+ influx into cells expressing NR1a/NR2A receptors (IC50 = 408 microM) and NR1a/NR2B receptors (EC50 = 37.3 microM), respectively.	Glycine	85-92	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	262-266
8647628-8	1996	Furthermore, epidermal growth factor (EGF), a stimulator of gastrin gene transcription, modulates gastrin-Gly secretion by AR4-2J.	Glycine	106-109	epidermal growth factor like 1	Rattus norvegicus	13-36
8647628-8	1996	Furthermore, epidermal growth factor (EGF), a stimulator of gastrin gene transcription, modulates gastrin-Gly secretion by AR4-2J.	Glycine	106-109	epidermal growth factor like 1	Rattus norvegicus	38-41
8612578-1	1996	The chick cerebellar kainate (KA) binding protein (KBP), a member of the family of ionotropic glutamate receptors, harbours a glycine-rich (GxGxxG) motif known to be involved in the binding of ATP and GTP to kinases and G proteins respectively.	Glycine	126-133	kainate binding protein	Gallus gallus	51-54
8743562-5	1996	MTSP-1 hydrolyzed tert-butyloxycarbonyl (Boc)-Asp(OBzl)Pro-Arg-amino-4-methyl-coumaryl-7-amide (MCA) and Boc-Ile-Glu-Gly-Arg-MCA faster than Boc-Phe-Ser-Arg-MCA.	Glycine	117-120	suppression of tumorigenicity 14 (colon carcinoma)	Mus musculus	0-6
8612643-4	1996	A highly conserved glycine-rich domain close to the carboxy-terminus was found in the GSH2 product and appears to be typical for eukaryotic glutathione synthetases.	Glycine	19-26	glutathione synthase	Saccharomyces cerevisiae S288C	86-90
8699132-3	1996	The aim of this study was to investigate the effect of TRH and its analogues (pGlu-HIs-Gly, pGlu-His-Gly-NH2) on cell proliferation in the intermediate pituitary lobe.	Glycine	87-90	thyrotropin releasing hormone	Rattus norvegicus	55-58
8566085-7	1996	The almost constant presence of glycine residues in the CDR3 and predominance of JH4 with a low level of DQ52 DH usage, suggest that preB cell clones are submitted to an initial selective pressure which should be antigen independent.	Glycine	32-39	CDR3	Homo sapiens	56-60
2480354-10	1989	A synthetic Arg-Gly-Asp-Ser tetrapeptide (RGDS), specific for fibronectin and vitronectin adhesion receptors, inhibited TRH-, EGF-, and TPA-induced GH4 cell stretching and attachment to fibronectin- and vitronectin-coated dishes.	Glycine	16-19	fibronectin 1	Rattus norvegicus	62-73
2480354-10	1989	A synthetic Arg-Gly-Asp-Ser tetrapeptide (RGDS), specific for fibronectin and vitronectin adhesion receptors, inhibited TRH-, EGF-, and TPA-induced GH4 cell stretching and attachment to fibronectin- and vitronectin-coated dishes.	Glycine	16-19	fibronectin 1	Rattus norvegicus	186-197
2557628-6	1989	The A2 and B1 proteins have a modular structure similar to that of the hnRNP protein A1: they contain two CS-RBDs and a glycine-rich auxiliary domain at the carboxyl terminus.	Glycine	120-127	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	71-76
2508560-8	1989	This mutation is theoretically equivalent to reversion of the Gly to Val transforming mutation of the cellular form of the ras gene product p21, a protein proposed to be structurally similar to EF-Tu in the GDP binding domain.	Glycine	62-65	H3 histone pseudogene 16	Homo sapiens	140-143
2633825-1	1989	It has been found out that tripeptide Arg-Gly-Asp being under natural conditions a fibronectin fragment, responsible for adhesion, is capable in vitro to stimulate ingestion ability of the rat blood polymorphonuclear leucocytes and monocytes.	Glycine	42-45	fibronectin 1	Rattus norvegicus	83-94
2806726-3	1989	In contrast, monoclonal antibodies directed against the collagen- and integrin-binding domains of fibronectin, or oligopeptides containing the fibronectin integrin-recognition sequence arg-gly-asp-ser, had no significant effect on condensation number.	Glycine	189-192	fibronectin 1	Gallus gallus	143-154
2682005-7	1989	Glycine----arginine mutation and glycine----valine mutation of codon 12 in ras p21 was observed in 40 and 31% of colon cancers, respectively.	Glycine	33-40	H3 histone pseudogene 16	Homo sapiens	79-82
2477372-11	1989	The homologous sequence in the chicken EGF receptor, which binds mouse EGF with a 100-fold lower affinity than the human EGF receptor, contains four amino acid differences including two in the Arg-Gly-Asp-Ser tetramer.	Glycine	197-200	epidermal growth factor	Mus musculus	39-42
2501795-1	1989	Amino acid sequencing of a CNBr digest of the tau protein isolated from bovine brain revealed an amino acid sequence of 17 residues, Pro-Gly-Leu-Lys-Glu-Ser-Pro-Leu-Gln-Ile-Gly-Ala-Ala-Pro-Gly-Leu-Lys, which we call peptide I, with heterogeneity at position 11 of glycine (peptide Ia) and proline (peptide Ib); peptide I showed no homology with the previously reported cDNA-derived mouse and human tau sequences.	Glycine	264-271	microtubule associated protein tau	Homo sapiens	46-49
2525104-0	1989	A substrate of the cell-attachment sequence of fibronectin (Arg-Gly-Asp-Ser) is sufficient to promote transition of arterial smooth muscle cells from a contractile to a synthetic phenotype.	Glycine	64-67	fibronectin 1	Rattus norvegicus	47-58
2525104-3	1989	Here, the ability of the cell-attachment sequence of fibronectin, Arg-Gly-Asp-Ser (RGDS), to promote this process was studied.	Glycine	70-73	fibronectin 1	Rattus norvegicus	53-64
2471068-1	1989	We have generated deletion mutants of the H-ras p21 protein which lack residues 58 to 63 or 64 to 68 and contain either the normal glycine or an activating mutation, arginine, at position 12.	Glycine	131-138	HRas proto-oncogene, GTPase	Homo sapiens	42-47
7487919-0	1995	The Gly-54--&gt;Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease.	Glycine	4-7	myelin basic protein	Homo sapiens	42-65
2471068-1	1989	We have generated deletion mutants of the H-ras p21 protein which lack residues 58 to 63 or 64 to 68 and contain either the normal glycine or an activating mutation, arginine, at position 12.	Glycine	131-138	H3 histone pseudogene 16	Homo sapiens	48-51
7487919-0	1995	The Gly-54--&gt;Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease.	Glycine	4-7	myelin basic protein	Homo sapiens	67-70
7487919-5	1995	A homozygous mutation at base pair 230 of the MBP gene results in a Gly-to-Asp substitution at the fifth collagen repeat.	Glycine	68-71	myelin basic protein	Homo sapiens	46-49
7487919-11	1995	Our results provide a biochemical basis for the functional deficit in the Gly-54--&gt;Asp allelic form of MBP and suggest that the proMASP/MASP binding site maps to the fifth collagen repeat of MBP.	Glycine	74-77	myelin basic protein	Homo sapiens	106-109
7476899-7	1995	Consistent with this hypothesis, ethanol significantly reduced glycine affinity at NR1/NR2A and NR1/NR2C receptors.	Glycine	63-70	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	87-91
7476899-9	1995	Activation of the NR1/NR2D heteromers by NMDA and low concentrations of glycine elicited responses characterized by an initial peak followed by a lower-amplitude plateau response, which is consistent with glycine-sensitive desensitization as previously described for native NMDA receptors.	Glycine	72-79	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	22-26
7476899-9	1995	Activation of the NR1/NR2D heteromers by NMDA and low concentrations of glycine elicited responses characterized by an initial peak followed by a lower-amplitude plateau response, which is consistent with glycine-sensitive desensitization as previously described for native NMDA receptors.	Glycine	205-212	glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog	Xenopus laevis	22-26
7567981-6	1995	All four mutations fall within a 62-residue region in the COOH-terminal domain of phyB, with two independent mutations occurring in a single amino acid, Gly-767.	Glycine	153-156	phytochrome B	Arabidopsis thaliana	82-86
8541847-2	1995	We have examined patients from three geographically distinct regions in the UK and found the GGT40 (Gly) to AGT40 (Ser) mutation to be present in 15/691 (2.2%) of patients with type 2 (non-insulin dependent) diabetes and 1/425 (0.2%) of geographically matched controls and have therefore replicated association of the GCG-R mutation with classical type 2 diabetes (Fisher"s exact test p = 0.008).	Glycine	100-103	glucagon receptor	Homo sapiens	318-323
8690729-12	1995	Thus, we could conclude that the 4th (Gly) residue on cystatin A must be small, because amino acids which existed on the N-terminal side of this residue could interact with a papain molecule.	Glycine	38-41	cystatin A	Homo sapiens	54-64
7501234-1	1995	We studied the mechanism by which thyrotropin-releasing hormone (TRH)-Gly stimulated prolactin and thyrotropin (TSH) secretion in pituitary, using a pituitary mammotropic cell line, GH3 cells, and a cell line stably expressing a human TRH receptor (TRH-R).	Glycine	70-73	thyrotropin releasing hormone	Rattus norvegicus	34-63
7501234-1	1995	We studied the mechanism by which thyrotropin-releasing hormone (TRH)-Gly stimulated prolactin and thyrotropin (TSH) secretion in pituitary, using a pituitary mammotropic cell line, GH3 cells, and a cell line stably expressing a human TRH receptor (TRH-R).	Glycine	70-73	thyrotropin releasing hormone	Rattus norvegicus	65-68
7642087-5	1995	The Gly-rich C-terminal domain possesses a limited ATP-dependent duplex-unwinding activity which contributes to the helicase activity of HDH IV/nucleolin.	Glycine	4-7	nucleolin	Homo sapiens	144-153
7549888-5	1995	The analysis revealed an interesting similarity between the segment around the beta 2-strand of alpha-amylase and the one around the beta 4-strand of glycolate oxidase that are flanked in loops by glycines and prolines.	Glycine	197-205	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	79-85
7798019-2	1995	C-terminal amidation of glycine extended gastrin (G-gly) to gastrin amide (G-amide) by peptidylglycine alpha-amidating mono-oxygenase (PAM) is the final processing step.	Glycine	24-31	peptidyl-glycine alpha-amidating monooxygenase	Ovis aries	135-138
7708754-6	1995	The Arg-Gly-Asp segment of this site in bovine Ang, which is replaced by Arg-Glu-Asn in human Ang, does not have a conformation typical of an integrin recognition site.	Glycine	8-11	angiogenin	Homo sapiens	47-50
7708754-6	1995	The Arg-Gly-Asp segment of this site in bovine Ang, which is replaced by Arg-Glu-Asn in human Ang, does not have a conformation typical of an integrin recognition site.	Glycine	8-11	angiogenin	Homo sapiens	94-97
7890620-4	1995	Human cystatin C variants with Gly substitutions for residues Arg-8, Leu-9, and/or Val-10 of the N-terminal binding region, and/or the evolutionarily conserved Trp-106 in the wedge-shaped binding region, were produced by site-directed mutagenesis and Escherichia coli expression.	Glycine	31-34	cystatin C	Homo sapiens	6-16
7630488-6	1995	In the absence of ethanol, glycine enhanced NMDA-induced currents with an EC50 of 1.42 microM for the NR1/NR2A combination and 0.51 microM for the NR1/NR2C combination.	Glycine	27-34	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	106-110
7875321-5	1995	The amino-terminal domain of hamster galectin 3, which is a repetitive sequence rich in glutamine, tyrosine, glycine and proline, is also an excellent substrate.	Glycine	109-116	galectin 3	Homo sapiens	37-47
7876099-12	1995	The deletion of Gly-117 in human sigma-ADH and a substitution of Leu for the bulky Tyr-110 appear to facilitate retinol access to the active-site zinc.	Glycine	16-19	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	Homo sapiens	33-42
7740072-4	1995	Attenuation of clonidine"s effect on growth hormone levels by NMDA receptor-associated glycine site antagonists appears most likely due to an interaction between their effects on the NMDA receptor complex with growth hormone releasing factor.	Glycine	87-94	gonadotropin releasing hormone receptor	Rattus norvegicus	37-51
7740072-4	1995	Attenuation of clonidine"s effect on growth hormone levels by NMDA receptor-associated glycine site antagonists appears most likely due to an interaction between their effects on the NMDA receptor complex with growth hormone releasing factor.	Glycine	87-94	gonadotropin releasing hormone receptor	Rattus norvegicus	210-224
7838136-7	1995	At comparable positions in SSTR5, these residues are glycine (G258) and phenylalanine (F265), respectively.	Glycine	53-60	somatostatin receptor type 5	Cricetulus griseus	27-32
21043620-4	1995	Thrombin-stimulated platelets but not non-stimulated platelets adhered to the SCSb-9coated surface, and platelet adherence was inhibited in a dose-dependent manner by the tetrapeptide RGDS (Arg-Gly-Asp-Ser).	Glycine	194-197	ral guanine nucleotide dissociation stimulator	Homo sapiens	184-188
7982933-7	1994	A cathepsin S double mutant Gly-133--&gt;Ala/Phe-205--&gt;Glu is characterized by somewhat improved kinetic parameters compared with the Phe-205--&gt;Glu single mutant.	Glycine	28-31	cathepsin S	Homo sapiens	2-13
7982933-9	1994	As with cathepsin B, the activities of the Phe-205--&gt;Glu single and the Gly-133--&gt;Ala/Phen-205--&gt;Glu double mutants of cathepsin S toward the dibasic substrate is modulated by an additional ionizable group with a pKa of 5.7.	Glycine	75-78	cathepsin S	Homo sapiens	128-139
7957114-6	1994	hnRNP A1B, which is an alternatively spliced isoform of hnRNP A1 with a longer Gly-rich domain, binds more strongly to pre-mRNA but has only limited alternative splicing activity.	Glycine	79-82	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	0-8
7849704-8	1994	These findings indicate that the G265-->A transition, involving the highly conserved glycine residue at the 89th position, is responsible for the CPO defect in the patient and accounts for the partial deficiency of CPO activity in this pedigree.	Glycine	85-92	coproporphyrinogen oxidase	Homo sapiens	146-149
7849704-8	1994	These findings indicate that the G265-->A transition, involving the highly conserved glycine residue at the 89th position, is responsible for the CPO defect in the patient and accounts for the partial deficiency of CPO activity in this pedigree.	Glycine	85-92	coproporphyrinogen oxidase	Homo sapiens	215-218
8083230-6	1994	Interestingly, one of the conserved serines of cPLA2, Ser-228, within this domain aligns with the lipase consensus sequence Gly-X(Leu)-Ser(137)-X(Gly)-Gly of PLB.	Glycine	124-127	phospholamban	Homo sapiens	158-161
8083230-6	1994	Interestingly, one of the conserved serines of cPLA2, Ser-228, within this domain aligns with the lipase consensus sequence Gly-X(Leu)-Ser(137)-X(Gly)-Gly of PLB.	Glycine	146-149	phospholamban	Homo sapiens	158-161
8083230-6	1994	Interestingly, one of the conserved serines of cPLA2, Ser-228, within this domain aligns with the lipase consensus sequence Gly-X(Leu)-Ser(137)-X(Gly)-Gly of PLB.	Glycine	146-149	phospholamban	Homo sapiens	158-161
8035831-0	1994	The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae.	Glycine	32-35	Gts1p	Saccharomyces cerevisiae S288C	4-8
7528345-7	1994	However, when jimpy brain proteolipids were subjected to N-terminal sequencing, Gly, Leu, Leu, Gly the first four amino acids of PLP were detected.	Glycine	80-83	proteolipid protein (myelin) 1	Mus musculus	129-132
7528345-7	1994	However, when jimpy brain proteolipids were subjected to N-terminal sequencing, Gly, Leu, Leu, Gly the first four amino acids of PLP were detected.	Glycine	95-98	proteolipid protein (myelin) 1	Mus musculus	129-132
7951320-4	1994	Sequencing of cDNA clones shows that the normal SYT gene encodes a protein rich in glutamine, proline and glycine, and indicates that in synovial sarcoma rearrangement of the SYT gene results in the formation of an SYT-SSX fusion protein.	Glycine	106-113	synaptotagmin 1	Homo sapiens	48-51
7951320-4	1994	Sequencing of cDNA clones shows that the normal SYT gene encodes a protein rich in glutamine, proline and glycine, and indicates that in synovial sarcoma rearrangement of the SYT gene results in the formation of an SYT-SSX fusion protein.	Glycine	106-113	synaptotagmin 1	Homo sapiens	175-178
7951320-4	1994	Sequencing of cDNA clones shows that the normal SYT gene encodes a protein rich in glutamine, proline and glycine, and indicates that in synovial sarcoma rearrangement of the SYT gene results in the formation of an SYT-SSX fusion protein.	Glycine	106-113	synaptotagmin 1	Homo sapiens	175-178
7518445-1	1994	PAC1 is an IgM kappa murine monoclonal antibody that, like the Arg-Gly-Asp-containing ligand fibrinogen, binds to integrin alpha IIb beta 3 only on activated platelets.	Glycine	67-70	dual specificity phosphatase 2	Homo sapiens	0-4
8182055-7	1994	Comparison of the sequences of the wild-type and chl3-1 NIA2 genes revealed a single base mutation changing a glycine codon to an aspartic acid codon.	Glycine	110-117	nitrate reductase 2	Arabidopsis thaliana	56-60
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog	Xenopus laevis	194-198
8190097-6	1994	Thus, glycine-independent stimulation by polyamines requires the presence of an NR1 variant, such as NR1A, that lacks the amino-terminal insert, but the manifestation of the stimulatory effect is controlled by the type of NR2 subunit present in a heteromeric complex.	Glycine	6-13	nodal homolog 2 L homeolog	Xenopus laevis	222-225
8019864-4	1994	It was found that glycine residues of proteins have five major clusters in the phi-psi conformational space, and two or three major clusters were found for the other kinds of residues.	Glycine	18-25	glucose-6-phosphate isomerase	Homo sapiens	79-82
2541362-7	1989	In contrast, the GnRH response to NMDA was reduced by Ca2+ (5.8 mM) and abolished in the absence of glycine or in the presence of Mg2+ (2 mM).	Glycine	100-107	gonadotropin releasing hormone 1	Rattus norvegicus	17-21
2541362-9	1989	The permissive effect of glycine on GnRH response to NMDA was 2.7-fold more important using glycine concentrations of 0.01 microM than when concentrations greater than or equal to 100 microM were used.	Glycine	25-32	gonadotropin releasing hormone 1	Rattus norvegicus	36-40
2541362-9	1989	The permissive effect of glycine on GnRH response to NMDA was 2.7-fold more important using glycine concentrations of 0.01 microM than when concentrations greater than or equal to 100 microM were used.	Glycine	92-99	gonadotropin releasing hormone 1	Rattus norvegicus	36-40
8019864-5	1994	Mode seeking on the potential surface of glycine residues identified their representative phi-psi conformational patterns: (82.64 degrees, 9.84 degrees), (-62.63 degrees, -41.71 degrees), (-85.33 degrees, 176.78 degrees), (91.88 degrees, 178.14 degrees) and (167.06 degrees, -175.33 degrees).	Glycine	41-48	glucose-6-phosphate isomerase	Homo sapiens	90-93
8132607-1	1994	Integrin alpha IIb-beta 3 binds fibrinogen via the recognition sequence Arg-Gly-Asp-Ser (RGDS).	Glycine	76-79	ral guanine nucleotide dissociation stimulator	Homo sapiens	89-93
8077255-1	1994	The adhesive interaction of cells with extracellular matrix components is essential for a variety of cellular functions, and is frequently mediated by a tetra peptide, Arg-Gly-Asp-Ser (RGDS), located within fibronectin and other proteins.	Glycine	172-175	ral guanine nucleotide dissociation stimulator	Homo sapiens	185-189
3207709-6	1988	The active site of the thioesterase domain of chicken fatty acid synthase was suggested to be the serine on position 101 according to its homology with other serine-type esterases and proteases which have a common structure of -Gly-X-Ser-Y-Gly- with the variable amino acids X and Y disrupting the homology.	Glycine	228-231	fatty acid synthase	Gallus gallus	54-73
3066243-6	1988	A synthetic peptide Gly-Arg-Gly-Asp-Ser, representing the host cell attachment site of fibronectin, partially inhibited the binding of fibronectin and of its 210 kD fragment to S dysgalactiae, but not to S equi.	Glycine	28-31	fibronectin 1	Bos taurus	87-98
3066243-6	1988	A synthetic peptide Gly-Arg-Gly-Asp-Ser, representing the host cell attachment site of fibronectin, partially inhibited the binding of fibronectin and of its 210 kD fragment to S dysgalactiae, but not to S equi.	Glycine	28-31	fibronectin 1	Bos taurus	135-146
7507461-3	1994	In this study we synthesized the recombinant polypeptide (HCV-NS5 antigen) with a 576 bp cDNA encoding a part of the NS5 region of the HCV genome that has the Gly-Asp-Asp motif.	Glycine	159-162	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	62-65
7507461-3	1994	In this study we synthesized the recombinant polypeptide (HCV-NS5 antigen) with a 576 bp cDNA encoding a part of the NS5 region of the HCV genome that has the Gly-Asp-Asp motif.	Glycine	159-162	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	117-120
7656024-4	1994	Analysis of the mutant DnaK756 protein, which has a lower affinity for GrpE, reveals a role for residue Gly 32 in GrpE binding.	Glycine	104-107	GrpE like 1, mitochondrial	Homo sapiens	71-75
3392532-9	1988	In another group of animals, fibers projecting mainly to the right PVCN and DCN were severed, which reduced [14C]glycine uptake and release by 33-47% in these subdivisions, but not in the right AVCN.	Glycine	113-120	decorin	Cavia porcellus	76-79
3294332-0	1988	Complement receptor type 3 (CR3) binds to an Arg-Gly-Asp-containing region of the major surface glycoprotein, gp63, of Leishmania promastigotes.	Glycine	49-52	leishmanolysin like peptidase	Homo sapiens	110-114
7656024-4	1994	Analysis of the mutant DnaK756 protein, which has a lower affinity for GrpE, reveals a role for residue Gly 32 in GrpE binding.	Glycine	104-107	GrpE like 1, mitochondrial	Homo sapiens	114-118
8289785-5	1994	Both Gly and Ala, substituted at PET54 position 244, disrupted the two-hybrid interactions with PET122 and PET494.	Glycine	5-8	Pet122p	Saccharomyces cerevisiae S288C	96-102
8289785-5	1994	Both Gly and Ala, substituted at PET54 position 244, disrupted the two-hybrid interactions with PET122 and PET494.	Glycine	5-8	Pet494p	Saccharomyces cerevisiae S288C	107-113
3135770-4	1988	The amino acid composition of canine C1q was similar to that of human C1q and contained a high percentage of glycine.	Glycine	109-116	complement C1q A chain	Homo sapiens	37-40
7905294-1	1993	Maximal L-glutamate/glycine-evoked currents were inhibited by ethanol in Xenopus laevis oocytes expressing recombinant heteromeric NMDA receptors consisting of NR1-NR2A, NR1-NR2B, and NR1-NR2C subunit combinations.	Glycine	20-27	glutamate receptor, ionotropic, N-methyl D-aspartate 2C L homeolog	Xenopus laevis	188-192
8167407-1	1993	Nucleolin (713 aa), a major nucleolar protein, presents two structural domains: a N-terminus implicated in interaction with chromatin and a C-terminus containing four RNA-binding domains (RRMs) and a glycine/arginine-rich domain mainly involved in pre-rRNA packaging.	Glycine	200-207	nucleolin	Homo sapiens	0-9
3365433-7	1988	This is consistent with previous in vitro findings that endopeptidase 24.11 has a higher affinity for the Ala-11-Tyr-12 and Gly-13-Trp-14 bonds in unsulphated G17, than in sulphated G17.	Glycine	124-127	thioredoxin domain containing 17	Homo sapiens	131-137
7504269-0	1993	Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence.	Glycine	132-135	insulin-like growth factor-binding protein 1	Cricetulus griseus	0-44
3122752-1	1988	The thioredoxin peptide Trp-Cys-Gly-Pro-Cys-Lys, which contains the redox active dithiol, was found to be reduced by lipoamide in a coupled reaction with lipoamide dehydrogenase and NADH.	Glycine	32-35	thioredoxin	Homo sapiens	4-15
8226878-5	1993	Most significantly a highly repetitive region (19 repeat units of 20 residues each), not found in either human or rat, enlarges one of the characteristic serine-glycine containing regions (designated CS-2) while the other serine-glycine containing domain (designated CS-1) is approximately one-fourth the length of the mammalian CS-1.	Glycine	161-168	ITPR interacting domain containing 2	Homo sapiens	329-333
7903167-4	1993	By performing glycine concentration-response curves and comparing EC50s, it was possible to show that the NR1 + NR2A + NR2C receptor preferentially co-assembled when all three subunit cDNAs were present.	Glycine	14-21	glutamate ionotropic receptor NMDA type subunit 2C	Homo sapiens	119-123
3426593-0	1987	Amino acid sequence of the phosphopyridoxyl peptide from P-protein of the chicken liver glycine cleavage system.	Glycine	88-95	OCA2 melanosomal transmembrane protein	Gallus gallus	57-66
3426593-1	1987	A pyridoxal 5"-phosphate-containing peptide which contained 54 amino acid residues was isolated from chicken liver P-protein of the glycine cleavage system following reduction with NaB3H4, carboxymethylation, and proteolysis with lysylendopeptidase.	Glycine	132-139	OCA2 melanosomal transmembrane protein	Gallus gallus	115-124
8405897-6	1993	The sequence His-Ala-Asp-Gly-Thr5-Phe-Thr-Asn-Asp-Met10-Thr-Ser-Tyr- Leu-Asp15-Ala-Lys-Ala-Ala-Arg20-Asp-Phe-Val-Ser-Trp25- Leu-Ala-Arg-Ser-Asp30- Lys-Ser shows 16 amino acid substitutions compared with the corresponding region of mammalian GLP-1 and 15 substitutions compared with that of salmon GLP.	Glycine	25-28	glucagon like peptide 1 receptor	Homo sapiens	241-246
2963209-2	1987	The normal c-myc and H-ras (Gly-12) were unable to immortalize cells under similar conditions.	Glycine	28-31	HRas proto-oncogene, GTPase	Rattus norvegicus	21-26
2443507-1	1987	The disialogangliosides GD2 and GD3 play a major role in the ability of human melanoma cells to attach to Arg-Gly-Asp-containing substrates such as fibronectin and vitronectin, since pretreatment of these cells with monoclonal antibodies to the oligosaccharide of GD2 and GD3 can inhibit their attachment and spreading on such adhesive proteins.	Glycine	110-113	GRDX	Homo sapiens	32-35
8003709-4	1993	The level of TRH-Gly and pre-pro-TRH (178-199) in the hypothalamus decreased significantly in groups A and B at 1-4 hours after the injection, and then returned to pretreatment levels at 24 h after the injection.	Glycine	17-20	thyrotropin releasing hormone	Rattus norvegicus	13-16
3674393-6	1987	The leakage of immobilized metal ions from the TSK gel chelate-5PW is apparent if the column is eluted by buffers containing low concentrations of (i) glycine or (ii) primary amines at round neutral pH.	Glycine	151-158	tsukushi, small leucine rich proteoglycan	Mus musculus	47-50
3110371-4	1987	Moreover, synapsin I-like proteins are still attached to the synaptic vesicles that were isolated in isotonic glycine solution from Torpedo electric organ by density gradient centrifugation and chromatography on Sephacryl-1000.	Glycine	110-117	synapsin-1	Bos taurus	10-20
3597437-3	1987	Bone proteoglycan II is 95% N terminally blocked and the small amount that can be sequenced has an amino-terminal sequence (NH2-Asp-Glu-Ala-()-Gly-Ile.	Glycine	143-146	decorin	Homo sapiens	0-20
2886057-6	1987	The parallelism between hepatic GGT activity and the biliary excretion of GS-hydrolysis products during development suggests a role for GGT in the formation of biliary Cys-Gly and Cys.	Glycine	172-175	gamma-glutamyltransferase 1	Rattus norvegicus	32-35
2886057-6	1987	The parallelism between hepatic GGT activity and the biliary excretion of GS-hydrolysis products during development suggests a role for GGT in the formation of biliary Cys-Gly and Cys.	Glycine	172-175	gamma-glutamyltransferase 1	Rattus norvegicus	136-139
3035212-7	1987	At position 12 in the p21 coding region, arginine is substituted for the naturally occurring glycine present in c-ras.	Glycine	93-100	H3 histone pseudogene 16	Homo sapiens	22-25
3304752-3	1987	The gene for human gastrin has been isolated, and it encodes a pre-pro-gastrin which is a 101-aminoacid peptide containing within it the structure of big gastrin (G34) with a C-terminal glycine extension.	Glycine	186-193	gastrin	Homo sapiens	19-26
3304752-3	1987	The gene for human gastrin has been isolated, and it encodes a pre-pro-gastrin which is a 101-aminoacid peptide containing within it the structure of big gastrin (G34) with a C-terminal glycine extension.	Glycine	186-193	gastrin	Homo sapiens	71-78
3304752-3	1987	The gene for human gastrin has been isolated, and it encodes a pre-pro-gastrin which is a 101-aminoacid peptide containing within it the structure of big gastrin (G34) with a C-terminal glycine extension.	Glycine	186-193	gastrin	Homo sapiens	71-78
3553445-0	1987	Visualization of endogenous glycine in cat retina: an immunocytochemical study with Fab fragments.	Glycine	28-35	FA complementation group B	Homo sapiens	84-87
3553445-1	1987	Fab fragments of a glycine antiserum were prepared and used for immunocytochemical visualization of glycine in the cat retina.	Glycine	19-26	FA complementation group B	Homo sapiens	0-3
3553445-1	1987	Fab fragments of a glycine antiserum were prepared and used for immunocytochemical visualization of glycine in the cat retina.	Glycine	100-107	FA complementation group B	Homo sapiens	0-3
2950119-0	1987	The fibronectin cell attachment sequence Arg-Gly-Asp-Ser promotes focal contact formation during early fibroblast attachment and spreading.	Glycine	45-48	fibronectin 1	Mus musculus	4-15
3091598-8	1986	With the exception of aminomalonate, bovine aminoacetone synthetase acts specifically on glycine and acetyl-CoA.	Glycine	89-96	glycine C-acetyltransferase	Bos taurus	44-67
3091598-9	1986	Coupled reactions of purified bovine aminoacetone synthetase and porcine L-threonine dehydrogenase demonstrated the interconversion of threonine and glycine.	Glycine	149-156	glycine C-acetyltransferase	Bos taurus	37-60
2428041-4	1986	In this study we report that the outgrowth of blastocysts on fibronectin-coated dishes is inhibited in a dose-dependent manner by the presence of a hexapeptide containing the sequence Arg-Gly-Asp, which has been shown previously to be recognized by the fibronectin receptor.	Glycine	188-191	fibronectin 1	Mus musculus	61-72
2428041-4	1986	In this study we report that the outgrowth of blastocysts on fibronectin-coated dishes is inhibited in a dose-dependent manner by the presence of a hexapeptide containing the sequence Arg-Gly-Asp, which has been shown previously to be recognized by the fibronectin receptor.	Glycine	188-191	fibronectin 1	Mus musculus	253-264
2428041-9	1986	These findings suggest that differentiation of cells of the trophectoderm into trophoblast cells with an invasive phenotype may involve the production of cell surface receptors for fibronectin and possibly for other proteins that contain the Arg-Gly-Asp recognition sequence.	Glycine	246-249	fibronectin 1	Mus musculus	181-192
3740840-9	1986	This interpretation is consistent with glycine stimulation of malate synthesis in the assay of PEPC coupled to malate dehydrogenase, with glycine stimulation of the decarboxylation of OAA, and with a reduction in the level of the M-OAAenol complex in the presence of glycine.	Glycine	39-46	MLO-like protein 4	Zea mays	95-99
2427157-1	1986	The localization of methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu)-like immunoreactivity in the medullospinal liquor-contacting neurons (LCNs) of the rat was immunohistochemically investigated using a modified Sternberger"s PAP method.	Glycine	47-50	proenkephalin	Rattus norvegicus	31-41
2427157-1	1986	The localization of methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu)-like immunoreactivity in the medullospinal liquor-contacting neurons (LCNs) of the rat was immunohistochemically investigated using a modified Sternberger"s PAP method.	Glycine	47-50	proenkephalin	Rattus norvegicus	62-65
2427157-2	1986	In this study, we also examined the distribution of Met-Enk-Arg-Gly-Leu-like immunoreactive LCNs in the entire length of the medulla oblongata and spinal cord.	Glycine	64-67	proenkephalin	Rattus norvegicus	56-59
2427157-7	1986	When the immunoreactivity of perikarya of LCNs was weak, a few nerve terminals with a strong Met-Enk-Arg-Gly-Leu-like immunoreactivity were noticed on them.	Glycine	105-108	proenkephalin	Rattus norvegicus	97-100
2427157-8	1986	These findings suggest that preproenkephalin A-related opioid peptides including Met-Enk-Arg-Gly-Leu may be secreted into the cerebrospinal fluid (CSF) through the terminal portions of axon-like processes and/or CSF-contacting processes of LCNs.	Glycine	93-96	proenkephalin	Rattus norvegicus	85-88
3007627-7	1986	The C1q contains hydroxyproline, hydroxylysine, a high percentage of glycine and approximately 7% carbohydrate.	Glycine	69-76	complement C1q A chain	Homo sapiens	4-7
3725864-4	1986	The exchange of the glycine residue by prolin in compounds former described caused a decreased antithrombin effect.	Glycine	20-27	serpin family C member 1	Homo sapiens	95-107
3755763-5	1986	However, a consensus organophosphate-binding hexapeptide sequence Phe-Gly-Glu-Ser-Ala-Gly was found both in "true" acetylcholinesterase from the electric organ of Torpedo [McPhee-Quigley et al: J Biol Chem 260:12185-12189, 1985] and in "pseudocholinesterase" (butyrylcholinesterase) from human serum [Lockridge: "Cholinesterases--Fundamental and Applied Aspects."	Glycine	70-73	butyrylcholinesterase	Homo sapiens	237-282
2997170-5	1985	Automated Edman degradation of trypsin-treated fructose-1,6-bisphosphatase following gel filtration shows a single sequence beginning at Gly-26 in the original enzyme, but no changes in the COOH-terminal region of fructose-1,6-bisphosphatase.	Glycine	137-140	fructose-bisphosphatase 1	Sus scrofa	47-74
2995356-4	1985	This proteolysis apparently cleaves ubiquitin at the carboxyl-terminal glycine dipeptide and results in inactivation of the molecule with respect to ligation but does not affect its mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	Glycine	71-78	ubiquitin	Oryctolagus cuniculus	36-45
3840161-4	1985	On Sephadex G-50 column chromatography of porcine antral mucosal extracts glycine-extended progastrin processing intermediates were separated into three principal molecular forms, each corresponding to known molecular forms of gastrin, component I, tetratriacontagastrin (G34) and heptadecagastrin (G17).	Glycine	74-81	gastrin	Homo sapiens	94-101
3840161-7	1985	Our findings indicate that glycine-extended progastrin processing intermediates may serve as immediate precursors for each molecular form of gastrin, thus suggesting an alternative pathway for gastrin biosynthesis more complex than that previously conceived.	Glycine	27-34	gastrin	Homo sapiens	47-54
3840161-7	1985	Our findings indicate that glycine-extended progastrin processing intermediates may serve as immediate precursors for each molecular form of gastrin, thus suggesting an alternative pathway for gastrin biosynthesis more complex than that previously conceived.	Glycine	27-34	gastrin	Homo sapiens	141-148
4054942-2	1985	The product was covalently coupled to a nonimmunogenic oligopeptide, representing an extracytoplasmic sequence of the receptor for the epidermal growth factor (EGF-R amino acids 516-529: Asn-Leu-Leu-Glu-Gly-Glu-Pro-Arg-Glu-Phe-Val-Glu-Asn-Ser).	Glycine	203-206	epidermal growth factor	Mus musculus	135-158
4054942-2	1985	The product was covalently coupled to a nonimmunogenic oligopeptide, representing an extracytoplasmic sequence of the receptor for the epidermal growth factor (EGF-R amino acids 516-529: Asn-Leu-Leu-Glu-Gly-Glu-Pro-Arg-Glu-Phe-Val-Glu-Asn-Ser).	Glycine	203-206	epidermal growth factor receptor	Mus musculus	160-165
2531294-7	1989	The use of site-directed antibodies implicates a small region of alpha- and beta-tubulin, containing the sequence Glu-Gly-Glu-Glu, as the site of the interaction of dynein and MAP2 with the microtubule.	Glycine	118-121	tubulin alpha 1b	Homo sapiens	65-88
2692710-2	1989	We have previously assigned all five glycine resonances located in loops directly involved in binding of guanosine diphosphate in the wild-type p21 protein [Campbell-Burk, S., Papastavros, M. Z., McCormick, F., &amp; Redfield, A. G. (1989) Proc.	Glycine	37-44	H3 histone pseudogene 16	Homo sapiens	144-147
2692710-7	1989	In this report, the corresponding glycine resonances in the p21 mutant have been assigned, and spectral differences between normal and mutant p21-guanosine diphosphate (p21.GDP) complexes have been investigated.	Glycine	34-41	H3 histone pseudogene 16	Homo sapiens	60-63
2692710-10	1989	Two of the five active-site glycines in wild-type p21.GDP have very slow amide proton exchange rates with water (kappa less than 2.8 x 10(-5) s-1).	Glycine	28-36	H3 histone pseudogene 16	Homo sapiens	50-53
2692710-11	1989	The active-site glycines are located in solvent-exposed loops, so their apparent solvent inaccessibility may result from strong hydrogen bond formation between glycine amide protons and bound guanine diphosphate and/or other nearby groups in p21.	Glycine	16-24	H3 histone pseudogene 16	Homo sapiens	242-245
2557455-0	1989	A polypeptide chain-refolding event occurs in the Gly82 variant of yeast iso-1-cytochrome c. The replacement of Phe82 in yeast iso-1-cytochrome c by a glycine residue substantially alters both the tertiary structure and electron transfer properties of this protein.	Glycine	151-158	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	73-78
2557455-0	1989	A polypeptide chain-refolding event occurs in the Gly82 variant of yeast iso-1-cytochrome c. The replacement of Phe82 in yeast iso-1-cytochrome c by a glycine residue substantially alters both the tertiary structure and electron transfer properties of this protein.	Glycine	151-158	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	127-132
2575217-1	1989	The tissue specific expression of peptidylglycine alpha-amidating monooxygenase [(PAM) EC 1.14.17.3], an enzyme which catalyzes the formation of amidated bioactive peptides from their glycine-extended precursors, was examined in adult rat.	Glycine	42-49	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	82-85
2554881-3	1989	We investigated the hydrolysis of cholecystokinin-8 [CCK-8; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2] and of various gastrin analogues by purified rabbit lung ACE.	Glycine	78-81	cholecystokinin	Oryctolagus cuniculus	53-56
2546737-4	1989	In control conditions (10 nM glycine and 1 mM mg2+), the release of GnRH in 7.5-min fractions collected for 2-4 h showed an obvious pulsatile pattern.	Glycine	29-36	gonadotropin releasing hormone 1	Rattus norvegicus	68-72
2546737-6	1989	The stimulation of GnRH release by NMDA (50 mM) added to the medium for 7.5 min could be blocked reversibly in the presence of MK-801 (100 microM) using medium without glycine or enriched with Mg2+ (2 mM).	Glycine	168-175	gonadotropin releasing hormone 1	Rattus norvegicus	19-23
2489085-1	1989	Anti-cell adhesive activity was examined by the synthetic polypeptide, containing repetitive Arg-Gly-Asp sequence of cell attachment site from fibronectin, poly (Arg-Gly-Asp).	Glycine	97-100	fibronectin 1	Mus musculus	143-154
2569702-0	1989	Glycine potentiates NMDA responses in rat hippocampal CA1 neurons.	Glycine	0-7	carbonic anhydrase 1	Rattus norvegicus	54-57
2569702-1	1989	When superfused onto rat hippocampal slices, glycine (0.1-0.5 mM) potentiated the depolarization induced by pressure application of NMDA in normal Krebs solution and the synaptic discharge evoked by stimulation of the Schaffer collateral-commissural inputs to the CA1 pyramidal neurons bathed in Mg2+-free media; the effects were not prevented by strychnine.	Glycine	45-52	carbonic anhydrase 1	Rattus norvegicus	264-267
2504277-8	1989	Additional screening of the library with a trypsinogen cDNA led to the isolation and sequencing of a full-length clone apparently coding for the complete sequence of a second tryptic serine protease (DMP) which is only 53.4% identical with the dog tryptase sequence but which contains an apparent signal/activation peptide also terminating in a glycine.	Glycine	345-352	mastin	Canis lupus familiaris	200-203
2686707-0	1989	Comparison of the computed structures for the phosphate-binding loop of the p21 protein containing the oncogenic site Gly 12 with the X-ray crystallographic structures for this region in the p21 protein and EFtu.	Glycine	118-121	H3 histone pseudogene 16	Homo sapiens	76-79
2686707-7	1989	We show that many computed structures for the Gly 12-containing phosphate binding loop, segment 9-15, are superimposable on the corresponding segment of the recently determined X-ray crystallographic structure for residues 1-171 of the p21 protein.	Glycine	46-49	H3 histone pseudogene 16	Homo sapiens	236-239
2686707-10	1989	This segment contains a Val residue where a Gly occurs in the p21 protein.	Glycine	44-47	H3 histone pseudogene 16	Homo sapiens	62-65
2784439-9	1989	These data suggest that the expression of integrin alpha subunits can be regulated differentially and independently of the beta subunit and that the VLA-1 heterodimer has an important function in mediating Arg-Gly-Asp-dependent cell adhesion or other phenotypic properties in human neuroblastoma cells.	Glycine	210-213	integrin subunit alpha 1	Homo sapiens	149-154
2706569-5	1989	Antibodies against the fibronectin receptor of CHO fibroblasts and short peptides containing the Arg-Gly-Asp sequence greatly reduced PGC adhesion to fibronectin.	Glycine	101-104	fibronectin 1	Mus musculus	23-34
2706569-5	1989	Antibodies against the fibronectin receptor of CHO fibroblasts and short peptides containing the Arg-Gly-Asp sequence greatly reduced PGC adhesion to fibronectin.	Glycine	101-104	fibronectin 1	Mus musculus	150-161
2521835-6	1989	These cells are able to adhere to fibronectin-coated dishes by a mechanism that is inhibitable by a synthetic hexapeptide containing the arg-gly-asp cell recognition sequence of fibronectin.	Glycine	141-144	fibronectin 1	Rattus norvegicus	34-45
2521835-6	1989	These cells are able to adhere to fibronectin-coated dishes by a mechanism that is inhibitable by a synthetic hexapeptide containing the arg-gly-asp cell recognition sequence of fibronectin.	Glycine	141-144	fibronectin 1	Rattus norvegicus	178-189
2918220-0	1989	Intracellular topography of glycine-extended pro-gastrin-processing intermediates in human antral mucosa: an electron-microscopic immunocytochemical study.	Glycine	28-35	gastrin	Homo sapiens	49-56
2918220-1	1989	To identify and characterize the subcellular topography of glycine-extended pro-gastrin-processing intermediates (G-Gly) in human antral mucosa, we performed an electron microscopic immunocytochemical study using region-specific antisera generated against the synthetic peptide, Tyr-Gly-Trp-Met-Asp-Phe-Gly (GL7), and C-terminal-specific anti-gastrin antisera.	Glycine	59-66	gastrin	Homo sapiens	80-87
2912899-0	1989	Antibodies raised against synthetic peptides from the Arg-Gly-Asp-containing region of the Leishmania surface protein gp63 cross-react with human C3 and interfere with gp63-mediated binding to macrophages.	Glycine	58-61	leishmanolysin like peptidase	Homo sapiens	118-122
2912899-0	1989	Antibodies raised against synthetic peptides from the Arg-Gly-Asp-containing region of the Leishmania surface protein gp63 cross-react with human C3 and interfere with gp63-mediated binding to macrophages.	Glycine	58-61	leishmanolysin like peptidase	Homo sapiens	168-172
2912899-2	1989	Antibody raised against a synthetic peptide containing the Arg-Gly-Asp region of the amino acid sequence of gp63 recognizes both gp63 and the alpha-chain of human C3.	Glycine	63-66	leishmanolysin like peptidase	Homo sapiens	108-112
2912899-2	1989	Antibody raised against a synthetic peptide containing the Arg-Gly-Asp region of the amino acid sequence of gp63 recognizes both gp63 and the alpha-chain of human C3.	Glycine	63-66	leishmanolysin like peptidase	Homo sapiens	129-133
2563332-1	1989	The present experiments describe a long-lasting form of potentiation induced in field CA1 of rat hippocampal slices by bath application of N-methyl-D-aspartate (NMDA), in association with low magnesium concentrations, glycine and spermine.	Glycine	218-225	carbonic anhydrase 1	Rattus norvegicus	86-89
2911604-1	1989	Peptidyl-glycine alpha-amidating monooxygenase (PAM; EC 1.14.17.3) catalyzes the conversion of a variety of glycine-extended peptides into biologically active alpha-amidated product peptides in a reaction dependent on copper, ascorbate, and molecular oxygen.	Glycine	9-16	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	48-51
2470110-1	1989	The disialogangliosides GD2 and GD3 play a major role in the ability of human melanoma cells to attach to Arg-Gly-Asp-containing substrates such as fibronectin and vitronectin, since pretreatment of these cells with monoclonal antibodies to the oligosaccharide of GD2 and GD3 can inhibit their attachment and spreading on such adhesive proteins.	Glycine	110-113	GRDX	Homo sapiens	32-35
3066243-6	1988	A synthetic peptide Gly-Arg-Gly-Asp-Ser, representing the host cell attachment site of fibronectin, partially inhibited the binding of fibronectin and of its 210 kD fragment to S dysgalactiae, but not to S equi.	Glycine	20-23	fibronectin 1	Bos taurus	87-98
3066243-6	1988	A synthetic peptide Gly-Arg-Gly-Asp-Ser, representing the host cell attachment site of fibronectin, partially inhibited the binding of fibronectin and of its 210 kD fragment to S dysgalactiae, but not to S equi.	Glycine	20-23	fibronectin 1	Bos taurus	135-146
2906363-3	1988	Lumbar CSF glycine concentrations rose with increasing age whilst GABA concentrations fell.	Glycine	11-18	colony stimulating factor 2	Homo sapiens	7-10
3292705-11	1988	It is concluded that LHRH degradation is primarily initiated by the membrane-bound form of endopeptidase-24.15 to yield pGlu-His-Trp-Ser-Tyr and to a lesser extent by endopeptidase-24.11 to yield pGlu-His-Trp-Ser-Tyr-Gly.	Glycine	217-220	gonadotropin releasing hormone 1	Mus musculus	21-25
2455726-8	1988	This "catch-up" was counteracted by a peptide that contained the cell-attachment sequence of fibronectin (Arg-Gly-Asp-Ser).	Glycine	110-113	fibronectin 1	Rattus norvegicus	93-104
3372531-2	1988	In the present studies, high levels of peptidylglycine alpha-amidating monooxygenase (PAM), which catalyzes the formation of bioactive alpha-amidated peptides from their glycine-extended precursors, have been found in particulate fractions from bovine and rat heart atrium; only low levels of PAM activity were present in soluble fractions.	Glycine	47-54	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	293-296
24310880-1	1985	The location on the wheat chloroplast DNA map and the nucleotide sequences of the genes coding for tRNA GCC (Gly) (trnG-GCC), tRNA GUC (Asp) (trnD-GUC) and tRNA GCA (Cys) (trnC-GCA) have been determined.	Glycine	109-112	trnG	Triticum aestivum	115-119
8003709-6	1993	The TRH-Gly, pre-pro-TRH (178-199) and TRH levels in other organs showed no changes after dexamethasone injection.	Glycine	8-11	thyrotropin releasing hormone	Rattus norvegicus	4-7
2966181-3	1988	Adhesion to fibronectin does not require platelet activation and is inhibited by soluble fibronectin, antibodies specific for fibronectin, peptides containing the sequence Arg-Gly-Asp and polyclonal antibodies specific for band 3 of the chicken embryo fibroblast fibronectin receptor (anti-band 3).	Glycine	176-179	fibronectin 1	Gallus gallus	12-23
8463322-0	1993	Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin.	Glycine	47-50	vinculin	Homo sapiens	172-180
8456807-4	1993	The relation between position of substitution of glycine by cysteine in the COL1A2 gene does not follow the pattern developed in the COL1A1 gene.	Glycine	49-56	collagen, type I, alpha 2	Mus musculus	76-82
3343338-1	1988	The experimental metastasis of B16-F10 murine melanoma cells is blocked by the anti-cell adhesive pentapeptide Gly-Arg-Gly-Asp-Ser (GRGDS) derived from the central cell-binding domain of fibronectin.	Glycine	111-114	fibronectin 1	Mus musculus	187-198
3343338-1	1988	The experimental metastasis of B16-F10 murine melanoma cells is blocked by the anti-cell adhesive pentapeptide Gly-Arg-Gly-Asp-Ser (GRGDS) derived from the central cell-binding domain of fibronectin.	Glycine	119-122	fibronectin 1	Mus musculus	187-198
3897912-6	1985	The Met-Enk-Arg-Gly-Leu-like immunoreactivity demonstrated in this study suggests the occurrence of preproenkephalin A and related opioid peptides.	Glycine	16-19	proenkephalin	Rattus norvegicus	8-11
8373751-1	1993	A tetrapeptide RGDS (Arg-Gly-Asp-Ser), which is one of the active sites of cell adhesive proteins, was synthesized according to the solution method and covalently coupled onto monodisperse microspheres.	Glycine	25-28	ral guanine nucleotide dissociation stimulator	Homo sapiens	15-19
3923480-1	1985	The conformational effects of different amino acid substitutions (lysine, serine, proline, and D-valine) for glycine at position 12 in the p21 oncogene-encoded proteins have been investigated by using conformational energy calculations.	Glycine	109-116	H3 histone pseudogene 16	Homo sapiens	139-142
3923480-2	1985	The normal cellular gene codes for a glycine at position 12 in the amino acid sequence, in the middle of a hydrophobic p21-(6-15)-decapepetide from Leu-6 to Gly-15.	Glycine	37-44	H3 histone pseudogene 16	Homo sapiens	119-122
3123489-2	1988	The covalent attachment of myristic acid to the NH2-terminal glycine residue of proteins is catalyzed by the enzyme myristoyl CoA:protein N-myristoyltransferase (NMT).	Glycine	61-68	glycylpeptide N-tetradecanoyltransferase 1	Triticum aestivum	138-160
8454570-2	1993	One of these sequences, Arg-Gly-Asp-Ser (RGDS) tetrapeptide, was shown to be transferred to a truncated form of Staphylococcal IgG-binding protein (hereafter referred to as tSPA) with retention of its cell-adhesive activity [Maeda, T. et al.	Glycine	28-31	ral guanine nucleotide dissociation stimulator	Homo sapiens	41-45
3123489-2	1988	The covalent attachment of myristic acid to the NH2-terminal glycine residue of proteins is catalyzed by the enzyme myristoyl CoA:protein N-myristoyltransferase (NMT).	Glycine	61-68	glycylpeptide N-tetradecanoyltransferase 1	Triticum aestivum	162-165
2985563-9	1985	Proteolytic inactivation of ubiquitin results from limited cleavage of the carboxyl-terminal glycine dipeptide required for isopeptide bond formation and is supported by data on isoelectric point changes on subsequent digestion with carboxypeptidase B and by direct amino acid analysis.	Glycine	93-100	ubiquitin	Oryctolagus cuniculus	28-37
3335304-5	1988	The disappearance curve of circulating glycine-extended gastrin could be described by two components with half-lives of 3.6 and 48 min.	Glycine	39-46	gastrin	Homo sapiens	56-63
8445347-3	1993	This peak, when incubated with purified bile acid CoA: amino acid N-acyltransferase (BAT) from human liver and either taurine or glycine, led to the formation of CDC-taurine or CDC-glycine, respectively.	Glycine	129-136	bile acid-CoA:amino acid N-acyltransferase	Homo sapiens	85-88
6334307-2	1984	The sequences of epidermal growth factor (EGF) and of the light chains from several components of the blood coagulation system also have one of the patterns, but gaps are required to adjust conserved cysteine and glycine residues in the second pattern.	Glycine	213-220	epidermal growth factor	Homo sapiens	17-40
6334307-2	1984	The sequences of epidermal growth factor (EGF) and of the light chains from several components of the blood coagulation system also have one of the patterns, but gaps are required to adjust conserved cysteine and glycine residues in the second pattern.	Glycine	213-220	epidermal growth factor	Homo sapiens	42-45
6427330-3	1984	At these positions, the results agree with the amino acid sequence deduced from the cDNA sequence determined previously by Koshland and co-workers and indicate that a leader sequence terminating in glycine is removed to form the mature J chain.	Glycine	198-205	immunoglobulin joining chain	Mus musculus	236-243
1477092-3	1992	An amino acid substitution in the exon 1 at codon 54 in the MBP gene (GGC [glycine] to GAC [aspartic acid]) has been shown to be closely associated with low MBP concentration in Caucasoids.	Glycine	75-82	myelin basic protein	Homo sapiens	60-63
1477092-3	1992	An amino acid substitution in the exon 1 at codon 54 in the MBP gene (GGC [glycine] to GAC [aspartic acid]) has been shown to be closely associated with low MBP concentration in Caucasoids.	Glycine	75-82	myelin basic protein	Homo sapiens	157-160
1304173-4	1992	By substituting carboxylic acids for axial glycines in the translated proteins both mutations would be expected to disrupt the secondary structure of the collagenous triple helix of the 96 kDa MBP subunits.	Glycine	43-51	myelin basic protein	Homo sapiens	193-196
6099767-2	1984	Neuronal cells possess angiotensin-converting enzyme (ACE), which splits the Gly-Phe bond and generates Tyr-Gly-Gly from enkephalin.	Glycine	77-80	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	54-57
1281859-0	1992	The two size alleles of human keratin 1 are due to a deletion in the glycine-rich carboxyl-terminal V2 subdomain.	Glycine	69-76	keratin 1	Homo sapiens	30-39
6325898-3	1983	It showed the following similarities to the normal C1q molecule: a high glycine content and the presence of hydroxyproline and hydroxylysine; subunits with apparent mol.	Glycine	72-79	complement C1q A chain	Homo sapiens	51-54
1400206-4	1992	One of the missense mutations (comC alpha 803) is a glycine-to-arginine change, and the resulting protein exhibits a substantially faster electrophoretic mobility.	Glycine	52-59	goF mRNA metabolism modulator	Escherichia phage T4	31-41
1527019-4	1992	The receptor, which consisted of two polypeptides of relative molecular masses of 150 and 116 kDa, bound to the entactin-Sepharose matrix in the presence of CaCl2, MgCl2, and MnCl2, and was eluted with EDTA, but not with Arg-Gly-Asp-containing peptides.	Glycine	225-228	nidogen 1	Homo sapiens	112-120
6308640-3	1983	These findings predicted that the resulting oncogene would code for a structurally altered p21 protein containing valine instead of glycine as its 12th amino acid residue.	Glycine	132-139	H3 histone pseudogene 16	Homo sapiens	91-94
6308640-8	1983	Computer analysis of the secondary structure of c-has/bas encoded p21 proteins indicates that substitution of the glycine residue located at position 12, not only by aspartic acid or valine but also by any other amino acid, would result in the same structural alteration.	Glycine	114-121	H3 histone pseudogene 16	Homo sapiens	66-69
1639059-1	1992	We have previously shown that a conserved glycine at position 82 of the yeast RAS2 protein is involved in the conversion of RAS proteins from the GDP- to the GTP-bound form.	Glycine	42-49	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	78-82
6190172-2	1983	The hydrolysis of an enkephalin analogue (Tyr-D-Ala-Gly-Phe-Leu) at the Gly-Phe bond was completely inhibited by phosphoramidon.	Glycine	52-55	proenkephalin	Sus scrofa	21-31
1500420-8	1992	Comparison of the data with the known primary structure of histone H2A revealed their amino acid sequence as 1Ser-Gly-Arg.	Glycine	114-117	histone cluster 1 H2A family member F	Rattus norvegicus	59-70
6754570-0	1982	[Exchange of A1-glycine in bovine insulin with L- and D-tryptophan].	Glycine	16-23	insulin	Bos taurus	34-41
1382726-7	1992	Peptides from plasmin digestion of fibronectin containing cell attachment site with sequence Arg-Gly-Asp-Ser and also synthetic peptide reproducing this amino-acid sequence at the concentration of 1000 micrograms/ml released about 50% of collagenase and 55% of elastase from PMN-leukocytes.	Glycine	97-100	plasminogen	Homo sapiens	14-21
6181193-2	1982	With myelin basic protein and one of its major peptic fragments (residues 89-169) as substrates, selective cleavage of Asp(32)-Thr(33), Asp(37)-Ser(38), and Glu(118-Gly(119) bonds was observed, as well as the unusual cleavage of the Gly(127)-Gly(128) bond.	Glycine	165-168	myelin basic protein	Cavia porcellus	5-25
6181193-2	1982	With myelin basic protein and one of its major peptic fragments (residues 89-169) as substrates, selective cleavage of Asp(32)-Thr(33), Asp(37)-Ser(38), and Glu(118-Gly(119) bonds was observed, as well as the unusual cleavage of the Gly(127)-Gly(128) bond.	Glycine	233-236	myelin basic protein	Cavia porcellus	5-25
7100893-1	1982	The present paper describes the structural analysis of an abnormal hemoglobin variant of alpha-chain found in a Chinese woman in the Hechi district of the Zhuang Autonomous Region of Guangxi, and finds it to be hemoglobin Handsworth (alpha 18(A16) Gly leads to Arg).	Glycine	248-251	immunoglobulin kappa variable 3-31 (pseudogene)	Homo sapiens	243-246
1737795-0	1992	Selective inactivation of the Arg-Gly-Asp-Ser (RGDS) binding site in von Willebrand factor by site-directed mutagenesis.	Glycine	34-37	ral guanine nucleotide dissociation stimulator	Homo sapiens	47-51
1536879-5	1992	When the mutants were microinjected into Xenopus oocytes, the non-phosphorylated forms of p21(Gly-12,Thr-59) and p21(Val-12,Thr-59) showed high activity.	Glycine	94-97	cyclin-dependent kinase inhibitor 1A L homeolog	Xenopus laevis	90-93
7253848-1	1981	Sodium fusidate and its glycine conjugate, which have the same detergent properties as bile acids, significantly (p less than 0.05) stimulate HMG-CoA reductase of cultured intestine below the critical micellar concentration (CMC) without affecting brush border enzymes.	Glycine	24-31	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	142-159
1733739-1	1992	The production of alpha-amidated peptide hormones from their glycine-extended precursors is catalyzed by the specific enzyme peptidylglycine alpha-amidating monooxygenase (PAM).	Glycine	61-68	peptidyl-glycine alpha-amidating monooxygenase	Ovis aries	125-170
7305948-10	1981	Mouse C1q contained hydroxyproline, hydroxylysine, a high percentage of glycine and approx.	Glycine	72-79	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	6-9
1733739-1	1992	The production of alpha-amidated peptide hormones from their glycine-extended precursors is catalyzed by the specific enzyme peptidylglycine alpha-amidating monooxygenase (PAM).	Glycine	61-68	peptidyl-glycine alpha-amidating monooxygenase	Ovis aries	172-175
1430422-2	1992	During a 48-h experiment 15N-labelled glycine was given orally in a dose of 5 mg 15N.kg bw-1 and urine samples were collected and analysed by an emission spectrometric isotope method.	Glycine	38-45	Body weight QTL1	Rattus norvegicus	88-92
6970196-6	1980	C1q contained hydroxyproline, hydroxylysine, a high percentage of glycine and approximately 9% carbohydrate and 14.8% nitrogen.	Glycine	66-73	complement C1q A chain	Homo sapiens	0-3
1898367-5	1991	The protein sequence of G7a contains two short consensus sequences, His-Ile-Gly-His and Lys-Met-Ser-Lys-Ser, which is the typical signature structure of class I tRNA synthetases and indicative of the presence of the Rossman fold.	Glycine	76-79	valyl-tRNA synthetase 1	Homo sapiens	24-27
6244123-2	1980	The COOH-terminal hexadecapeptide fragment of gastrin-17 was coupled at the NH2-terminal glycine residue to iodinated 3-(4-hydroxyphenyl) propionic acid N-hydroxysuccinimide ester.	Glycine	89-96	gastrin	Homo sapiens	46-53
7430648-3	1980	The purified C1q was heat-labile (56 degrees C, 30 min) both structurally and functionally, contained 4.3% hydroxyproline, 1.38% hydroxylysine, and 18.5% glycine, had an apparent molecular weight of 380,000 daltons, and reconstituted the hemolytic complement activity of C1q-depleted mouse serum.	Glycine	154-161	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	13-16
1931813-4	1991	The TCR CDR3s of both alpha and beta chains are particularly rich in Gly, whereas the CDR1 and CDR2 loops exhibit strong biases in favour of charged residues.	Glycine	69-72	CDR3	Homo sapiens	8-12
3057195-5	1988	PP14 and human retinol-binding protein show a 23% sequence identity, and the amino acid residues -Gly-Thr-Trp- at positions 17-19 of PP14 are identical with the corresponding residues of human retinol-binding protein.	Glycine	98-101	progestagen associated endometrial protein	Homo sapiens	133-137
1869824-8	1991	Using a larger panel of homozygous B cell lines expressing many class II haplotypes, a Ser-309 substituted HA307-319 analogue was shown to bind to most B cell lines expressing Val-86 containing alleles (including DR1 Dw20 and DR4 Dw14) but failed to bind most B cell lines expressing Gly-86 alleles (including DR1 Dw1 and DR4 Dw4).	Glycine	284-287	down-regulator of transcription 1	Homo sapiens	310-313
3328019-8	1987	The probability for the normal p21 containing glycine as residue 12 is greatest, and the cancer-associated variants show less probabilities.	Glycine	46-53	H3 histone pseudogene 16	Homo sapiens	31-34
1856866-3	1991	For this insulin molecule, the first without detectable activity to be characterized, the A and B-chains are linked by a peptide bond between A1 Gly and B29 Lys.	Glycine	145-148	insulin	Sus scrofa	9-16
2958379-4	1987	In the case of fibronectin, the rate of outgrowth in the presence of the heparin is slower than in the presence of the Arg-Gly-Asp-Ser-containing peptide that is recognized by a fibronectin receptor.	Glycine	123-126	fibronectin 1	Mus musculus	15-26
2958379-4	1987	In the case of fibronectin, the rate of outgrowth in the presence of the heparin is slower than in the presence of the Arg-Gly-Asp-Ser-containing peptide that is recognized by a fibronectin receptor.	Glycine	123-126	fibronectin 1	Mus musculus	178-189
516180-0	1979	[Peculiarities of histones H1, H2b and H4 structure and aggregation in the presence of glycine].	Glycine	87-94	H2B clustered histone 21	Homo sapiens	31-34
516180-1	1979	The efficiency of intramolecular and intermolecular interactions of histons H1, H2b and H4 was studied as affected by the glycine concentration in the composition of the glycine-HCl buffer (pH 3.0).	Glycine	122-129	H2B clustered histone 21	Homo sapiens	80-83
516180-5	1979	In the presence of glycine the sizes of histone aggregates decrease in the series H1 greater than H2b greater than H4.	Glycine	19-26	H2B clustered histone 21	Homo sapiens	98-101
1712019-6	1991	GP-II corresponded to a part of GP-I, its sequence being Leu-Ser*-Glu-Ser*-Thr*-Thr*-Gln-Leu-Pro-Gly, where asterisks denote amino acids to which an alpha-GalNAc residue is attached.	Glycine	97-100	glucose-6-phosphate isomerase	Homo sapiens	0-4
363726-5	1978	Synthesis and secretion of fibronectin into the medium are shown by anabolic labeling with [35S]methionine or [3H]glycine, and identification of the secreted proteins by immunoprecipitation and sodium dodecyl sulfate (SDS)-disc gel electrophoresis.	Glycine	114-121	fibronectin 1	Gallus gallus	27-38
3631267-3	1987	By use of isolated 5-cm segments of rat jejunum, we determined that maximal activation of ODC occurred after a 2-h exposure to 0.6 M glycine.	Glycine	133-140	ornithine decarboxylase 1	Rattus norvegicus	90-93
1850389-2	1991	In the presence of 10 mM D-glucose the C-terminal nonapeptide Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 (S19-27) showed a 2-fold higher activity than that earlier shown for S22-27 and had the same effect on the dynamic pattern of insulin release as secretin, while the elongating sequence Leu-Gln-Arg (S19-21) had no effect on the insulin release.	Glycine	86-89	secretin	Mus musculus	247-255
3676243-4	1987	Glycine is one substrate for the enzyme glutathione synthase (EC 6.3.2.3) and in the inborn error of metabolism in which glutathione synthase function is defective, increased quantities of 5-oxoproline are excreted in the urine.	Glycine	0-7	glutathione synthetase	Homo sapiens	40-60
3676243-4	1987	Glycine is one substrate for the enzyme glutathione synthase (EC 6.3.2.3) and in the inborn error of metabolism in which glutathione synthase function is defective, increased quantities of 5-oxoproline are excreted in the urine.	Glycine	0-7	glutathione synthetase	Homo sapiens	121-141
730034-0	1978	Effect of bovine insulin on the incorporation of [14C]glycine into protein and carbohydrate in liver and muscle of hagfish, Eptatretus stouti.	Glycine	49-61	insulin	Bos taurus	17-24
3297170-1	1987	Enkephalinase B from rat brain membrane which hydrolyzes enkephalin at the Gly-Gly bond was purified about 9400-fold to apparent electrophoretic homogeneity.	Glycine	75-78	proenkephalin	Rattus norvegicus	57-67
2078867-1	1990	Two cytochrome b respiratory-deficient mutants were sequenced and their DNA base change identified, leading to the replacement of glycine (G137 by valine or glutamic acid.	Glycine	130-137	cytochrome b	Saccharomyces cerevisiae S288C	4-16
3297170-1	1987	Enkephalinase B from rat brain membrane which hydrolyzes enkephalin at the Gly-Gly bond was purified about 9400-fold to apparent electrophoretic homogeneity.	Glycine	79-82	proenkephalin	Rattus norvegicus	57-67
3302715-2	1987	The main catabolic pathway of nutritional glycine proceeds via the glycine-cleavage enzyme, serinehydroxymethyltransferase and serinedehydratase or serine-pyruvate aminotransferase and via serine and pyruvate.	Glycine	42-49	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	148-180
3024151-5	1986	An interesting observation is the Gly-Arg-Gly-Asp-Ser sequence, which is identical to the cell-binding sequence identified in fibronectin.	Glycine	34-37	fibronectin 1	Rattus norvegicus	126-137
270715-9	1977	Removal of the three COOH-terminal residues, Gly-Glu-Glu, from fragment 60--78 decreased the ability to activate LPL by greater than 95%.	Glycine	45-48	lipoprotein lipase	Homo sapiens	113-116
869925-3	1977	The content of glycine, proline and dicarboxylicamino acids accounts for 83% of the total resideus of protein C and it contains 2.0 mol of P/mol of protein, most likely as phosphoserine.	Glycine	15-22	protein C, inactivator of coagulation factors Va and VIIIa	Homo sapiens	102-111
3024151-5	1986	An interesting observation is the Gly-Arg-Gly-Asp-Ser sequence, which is identical to the cell-binding sequence identified in fibronectin.	Glycine	42-45	fibronectin 1	Rattus norvegicus	126-137
2126612-2	1990	We used specific radioimmunoassays to measure TRH-Gly and TRH levels in rat cortex, hypothalamus, medulla, eyes and whole blood as a function of the intracisternal (IC) dose of TRH and TRH-Gly administered 40 min prior to sacrifice.	Glycine	50-53	thyrotropin releasing hormone	Rattus norvegicus	46-49
197035-3	1977	A solution synthesis of Z-Gly-Thr-Lys (Tfa)-Met-Ile-Phe-Ala-Gly-Ile-Lys (Tfa)-Lys (Tfa)-NHNH-Boc corresponding to the sequence 77-87 of horse heart cytochrome c is described.	Glycine	26-29	cytochrome c, somatic	Equus caballus	148-160
892988-3	1977	A description is given of the synthesis by fragment condensation of the peptides Glu-Ser-Ser-Ala-Asp-Lys-Phe-Lys-Arg-Gln-His-Met-Asp and Gly-Glu-Ser-Arg-Glu-Ser-Ser-Ala-Asp-Lys-Phe-Lys-Arg-Gln-His-Met-Asp respectively corresponding to the 5-17 and 1-17 amino acid sequences of rat pancreatic ribonuclease.	Glycine	137-140	ribonuclease A family member 1, pancreatic	Rattus norvegicus	281-304
952873-6	1976	Galactosyltransferase was inactivated with a [3H]UDP derivative and the predominant labeled peptide, from thermolysin digestion, isolated and characterized as: Ser-Gly-Lys-UDP.	Glycine	164-167	N-acetyllactosaminide alpha-1,3-galactosyltransferase	Bos taurus	0-21
3028371-1	1986	We have prepared a semisynthetic analogue of fully acetimidylated horse cytochrome c, a complex in which the peptide bond between residues glycine-37 and arginine-38 is lacking.	Glycine	139-146	cytochrome c, somatic	Equus caballus	72-84
3015948-0	1986	A study of roles of evolutionarily invariant proline 30 and glycine 34 of cytochrome c.	Glycine	60-67	cytochrome c, somatic	Equus caballus	74-86
2126612-4	1990	The relative potency of IC and intracardiac (IK) TRH and TRH-Gly release of rat TSH was compared by radioimmunoassay and further refined using estimates based on in vivo kinetics of TRH-Gly alpha-amidation.	Glycine	61-64	thyrotropin releasing hormone	Rattus norvegicus	57-60
2126612-4	1990	The relative potency of IC and intracardiac (IK) TRH and TRH-Gly release of rat TSH was compared by radioimmunoassay and further refined using estimates based on in vivo kinetics of TRH-Gly alpha-amidation.	Glycine	61-64	thyrotropin releasing hormone	Rattus norvegicus	57-60
2126612-7	1990	IK TRH-Gly had 0.16% of the potency of IK TRH of TSH release and was also consistent with its rate of intravascular conversion to TRH.	Glycine	7-10	thyrotropin releasing hormone	Rattus norvegicus	3-6
2126612-7	1990	IK TRH-Gly had 0.16% of the potency of IK TRH of TSH release and was also consistent with its rate of intravascular conversion to TRH.	Glycine	7-10	thyrotropin releasing hormone	Rattus norvegicus	42-45
2126612-7	1990	IK TRH-Gly had 0.16% of the potency of IK TRH of TSH release and was also consistent with its rate of intravascular conversion to TRH.	Glycine	7-10	thyrotropin releasing hormone	Rattus norvegicus	42-45
3001099-18	1986	No protein was recovered, however, upon elution with 4 mM EGTA, but elution with 0.1 M glycine-HCl, pH 2.8, released bound brevin or gelsolin and actin.	Glycine	87-94	gelsolin	Homo sapiens	123-129
3001099-18	1986	No protein was recovered, however, upon elution with 4 mM EGTA, but elution with 0.1 M glycine-HCl, pH 2.8, released bound brevin or gelsolin and actin.	Glycine	87-94	gelsolin	Homo sapiens	133-141
2126612-8	1990	The mean peak TSH response occurred at 20 min after IC TRH-Gly or IC TRH injection but the post-peak decline was slower for IC TRH-Gly.	Glycine	59-62	thyrotropin releasing hormone	Rattus norvegicus	55-58
2149877-3	1990	In the oocyte 5,7-dichlorokynurenic acid (5,7-DCK) was a competitive blocker of the glycine recognition site on NMDA receptors, and was more potent (KB 65 nM in Schild analysis) and selective (509-fold more potent vs glycine than kainate) than the prototype glycine antagonist, 7-chlorokynurenic acid, 5,7-DCK also reduced NMDA-induced neuron injury in rat cortical cell cultures.	Glycine	84-91	deoxycytidine kinase	Rattus norvegicus	46-49
2870431-7	1986	Thus as major split position the Gly-Phe bond in the insulin B-chain could be identified.	Glycine	33-36	insulin	Bos taurus	53-60
52300-9	1975	This study suggests: (1) specific proteins or amino acids may be responsible for different developmental measures; (2) injudicious dietary restrictions in pregnancy should be avoided; (3) the determination of alpha1 globulin and a few amino acids such as glycine, lysine, and histidine in late pregancy may be used as predictors of fetal growth and development.	Glycine	255-262	adrenoceptor alpha 1D	Homo sapiens	209-215
5579642-6	1971	The estimated K(m) value of glycine was 3.1 x 10(-5)M, and V(max) was 0.48 mu-mole/min.g cord.6.	Glycine	28-35	guanylate cyclase 2D, retinal	Homo sapiens	89-95
2149877-3	1990	In the oocyte 5,7-dichlorokynurenic acid (5,7-DCK) was a competitive blocker of the glycine recognition site on NMDA receptors, and was more potent (KB 65 nM in Schild analysis) and selective (509-fold more potent vs glycine than kainate) than the prototype glycine antagonist, 7-chlorokynurenic acid, 5,7-DCK also reduced NMDA-induced neuron injury in rat cortical cell cultures.	Glycine	217-224	deoxycytidine kinase	Rattus norvegicus	46-49
3007933-6	1986	The mutation points were located at different positions in the RepB protein coding region (Gly to Asp for pRBHC3 and Gly to Glu for pRBHC7).	Glycine	91-94	Replication protein repB	Staphylococcus aureus	63-67
3007933-6	1986	The mutation points were located at different positions in the RepB protein coding region (Gly to Asp for pRBHC3 and Gly to Glu for pRBHC7).	Glycine	117-120	Replication protein repB	Staphylococcus aureus	63-67
2149877-3	1990	In the oocyte 5,7-dichlorokynurenic acid (5,7-DCK) was a competitive blocker of the glycine recognition site on NMDA receptors, and was more potent (KB 65 nM in Schild analysis) and selective (509-fold more potent vs glycine than kainate) than the prototype glycine antagonist, 7-chlorokynurenic acid, 5,7-DCK also reduced NMDA-induced neuron injury in rat cortical cell cultures.	Glycine	217-224	deoxycytidine kinase	Rattus norvegicus	46-49
2121465-8	1990	The mean ratio of TRH-Gly/TRH concentrations was less than 1 in neural tissues and pancreas.	Glycine	22-25	thyrotropin releasing hormone	Rattus norvegicus	18-21
5545117-8	1971	Glutathione synthetase also catalyzes an exchange reaction between glycine and glutathione, but this reaction is not significant under the conditions used for assay of hemolysates.	Glycine	67-74	glutathione synthetase	Homo sapiens	0-22
2165127-5	1990	Analyses of the gD genes by dideoxy-sequencing techniques identified a base difference in the coding sequences and predicted that the ANG gD gene codes for alanine (GCC codon) at amino acid position 84 in the open reading frame and the ANG path gD gene codes for glycine (GGC codon) at this site.	Glycine	263-270	angiogenin, ribonuclease, RNase A family, 5	Mus musculus	134-137
14187691-0	1964	EFFECT OF DIETARY GLYCINE ON TRANSAMIDINASE ACTIVITY OF TUMOR BEARING MICE.	Glycine	18-25	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	Mus musculus	29-43
2932492-2	1985	Similarly the activity of the enzyme serine hydroxymethyltransferase (SHMT) which cleaves serine to glycine, was significantly lower (P less than 0.0001) in psychotics than in nonpsychotics.	Glycine	100-107	serine hydroxymethyltransferase 1	Homo sapiens	37-68
2932492-2	1985	Similarly the activity of the enzyme serine hydroxymethyltransferase (SHMT) which cleaves serine to glycine, was significantly lower (P less than 0.0001) in psychotics than in nonpsychotics.	Glycine	100-107	serine hydroxymethyltransferase 1	Homo sapiens	70-74
3018530-0	1985	A mutation allowing an mRNA secondary structure diminishes translation of Saccharomyces cerevisiae iso-1-cytochrome c. The CYC1-239-O mutation in the yeast Saccharomyces cerevisiae produces a -His-Leu- replacement of the normal -Ala-Gly- sequence at amino acid positions 5 and 6, which lie within a dispensable region of iso-1-cytochrome c; this mutation can accommodate the formation of a hairpin structure at the corresponding site in the mRNA.	Glycine	233-236	cytochrome c isoform 1	Saccharomyces cerevisiae S288C	123-127
2165127-5	1990	Analyses of the gD genes by dideoxy-sequencing techniques identified a base difference in the coding sequences and predicted that the ANG gD gene codes for alanine (GCC codon) at amino acid position 84 in the open reading frame and the ANG path gD gene codes for glycine (GGC codon) at this site.	Glycine	263-270	angiogenin	Homo sapiens	236-239
33931009-0	2021	Effect of the glycine-rich domain in GAREM2 on its unique subcellular localization upon EGF stimulation.	Glycine	14-21	GRB2 associated regulator of MAPK1 subtype 2	Rattus norvegicus	37-43
33931009-7	2021	Based on the observed subcellular localizations of chimeric GAREM1 and GAREM2 proteins, a glycine-rich region, which is present only in GAREM2, is required for the observed granule formation.	Glycine	90-97	GRB2 associated regulator of MAPK1 subtype 2	Rattus norvegicus	71-77
2194551-1	1990	The gag proteins of HIV-1 are modified by the addition of myristic acid to the amino terminal glycine residue.	Glycine	94-101	Pr55(Gag)	Human immunodeficiency virus 1	4-7
33931009-7	2021	Based on the observed subcellular localizations of chimeric GAREM1 and GAREM2 proteins, a glycine-rich region, which is present only in GAREM2, is required for the observed granule formation.	Glycine	90-97	GRB2 associated regulator of MAPK1 subtype 2	Rattus norvegicus	136-142
2113484-2	1990	TRH-extended peptides have been detected in the rat olfactory lobe: these peptides accounted for approximately 11% of the total TRH immunoreactivity present in the tissue and contained the sequence pGlu-His-Pro-Gly-Arg exclusively at their N-termini.	Glycine	211-214	thyrotropin releasing hormone	Rattus norvegicus	0-3
33931009-9	2021	CONCLUSIONS: Our results, showing that aggregation of GAREM2 in response to EGF stimulation is dependent on a glycine-rich region, suggest that GAREM2 aggregation may be involved in neurodegenerative diseases.	Glycine	110-117	GRB2 associated regulator of MAPK1 subtype 2	Rattus norvegicus	54-60
33931009-9	2021	CONCLUSIONS: Our results, showing that aggregation of GAREM2 in response to EGF stimulation is dependent on a glycine-rich region, suggest that GAREM2 aggregation may be involved in neurodegenerative diseases.	Glycine	110-117	GRB2 associated regulator of MAPK1 subtype 2	Rattus norvegicus	144-150
1696816-3	1990	The binding of the fragments to a dansylated synthetic human MBP peptide gly(119)-gly(131), presenting sequence homologies with a viral protein, was measured in buffer and for the first time in reverse micelles of sodium bis(2-ethylhexyl) sulfosuccinate, in isooctane.	Glycine	73-76	myelin basic protein	Homo sapiens	61-64
33850892-8	2021	The residues of the TCR alpha or beta chains that interacted with peptides were replaced by alanine (Ala) or glycine (Gly), and their intermolecular binding free energy of the complex had been improved.	Glycine	109-116	T cell receptor alpha joining 60 (pseudogene)	Homo sapiens	20-29
33850892-8	2021	The residues of the TCR alpha or beta chains that interacted with peptides were replaced by alanine (Ala) or glycine (Gly), and their intermolecular binding free energy of the complex had been improved.	Glycine	118-121	T cell receptor alpha joining 60 (pseudogene)	Homo sapiens	20-29
1696816-3	1990	The binding of the fragments to a dansylated synthetic human MBP peptide gly(119)-gly(131), presenting sequence homologies with a viral protein, was measured in buffer and for the first time in reverse micelles of sodium bis(2-ethylhexyl) sulfosuccinate, in isooctane.	Glycine	82-85	myelin basic protein	Homo sapiens	61-64
2176799-4	1990	The obtained IP-gly seemed, by its analytical and biological properties, to be identical, or similar, to the previously described insulin mediator.	Glycine	16-19	insulin	Sus scrofa	130-137
33284994-6	2021	An independence of MYCN-amplified cells from exogenous serine and glycine was demonstrated by serine and glycine starvation, which attenuated nucleotide pools and proliferation only in cells with diploid MYCN but did not diminish these endpoints in MYCN-amplified cells.	Glycine	66-73	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	19-23
33284994-6	2021	An independence of MYCN-amplified cells from exogenous serine and glycine was demonstrated by serine and glycine starvation, which attenuated nucleotide pools and proliferation only in cells with diploid MYCN but did not diminish these endpoints in MYCN-amplified cells.	Glycine	105-112	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	19-23
33428810-1	2021	Glycine transporters (GlyT1 and GlyT2) that regulate levels of brain glycine, an inhibitory neurotransmitter with co-agonist activity for NMDA receptors (NMDARs), have been considered to be important targets for the treatment of brain disorders with suppressed NMDAR function such as schizophrenia.	Glycine	69-76	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	22-27
2325663-1	1990	Peptidylglycine alpha-amidating monooxygenase (PAM; EC 1.14.17.3) catalyzes the production of alpha-amidated peptides from their glycine-extended precursors, a posttranslational modification often required for full biological activity.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Bos taurus	47-50
33428810-1	2021	Glycine transporters (GlyT1 and GlyT2) that regulate levels of brain glycine, an inhibitory neurotransmitter with co-agonist activity for NMDA receptors (NMDARs), have been considered to be important targets for the treatment of brain disorders with suppressed NMDAR function such as schizophrenia.	Glycine	69-76	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	32-37
33428810-1	2021	Glycine transporters (GlyT1 and GlyT2) that regulate levels of brain glycine, an inhibitory neurotransmitter with co-agonist activity for NMDA receptors (NMDARs), have been considered to be important targets for the treatment of brain disorders with suppressed NMDAR function such as schizophrenia.	Glycine	69-76	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	154-159
33428810-6	2021	Elevating glycine levels back to normal ranges by antisense oligonucleotide-induced SLC6A20 knockdown, or the competitive GlyT1 antagonist sarcosine, normalized NMDAR currents and repetitive climbing behavior observed in these mice.	Glycine	10-17	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	161-166
33428810-8	2021	Lastly, both mouse and human SLC6A20 proteins mediated proline and glycine transports, and SLC6A20 proteins could be detected in human neurons.	Glycine	67-74	solute carrier family 6 member 20	Homo sapiens	29-36
33428810-9	2021	These results suggest that SLC6A20 regulates proline and glycine homeostasis in the brain and that SLC6A20 inhibition has therapeutic potential for brain disorders involving NMDAR hypofunction.	Glycine	57-64	solute carrier family 6 member 20	Homo sapiens	27-34
33462517-4	2021	Here we show that cholesterol in GP-containing membranes enhances fusion and the membrane-proximal external region and transmembrane (MPER/TM) domain of GP interacts with cholesterol via several glycine residues in the GP2 TM domain, notably G660.	Glycine	195-202	ring finger protein 130	Homo sapiens	33-35
33462517-4	2021	Here we show that cholesterol in GP-containing membranes enhances fusion and the membrane-proximal external region and transmembrane (MPER/TM) domain of GP interacts with cholesterol via several glycine residues in the GP2 TM domain, notably G660.	Glycine	195-202	ring finger protein 130	Homo sapiens	153-155
33569080-2	2021	Mutation of AMT or GLDC, encoding the GCS components aminomethyltransferase and glycine decarboxylase, can cause malformations of the developing CNS (neural tube defects (NTDs) and ventriculomegaly) as well as a post-natal life-limiting neurometabolic disorder, Non-Ketotic Hyperglycinemia.	Glycine	80-87	aminomethyltransferase	Mus musculus	12-15
33171153-1	2021	D-serine plays an important role in modulating N-methyl-D-aspartate receptor (NMDAR) neurotransmission in the mammalian brain by binding to the receptor"s glycine modulatory site (GMS).	Glycine	155-162	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	78-83
33601878-3	2021	In each module, genes with the most connectivity were selected as hub genes, including G antigen 12J (GAGE12J) in blue, proline, histidine and glycine rich 1 (PHGR1) in dark orange, DNA polymerase gamma 2, accessory subunit (POLG2) in dark red and collagen type XXI alpha 1 chain (COL21A1) in dark violet.	Glycine	143-150	Rho GTPase activating protein 17	Homo sapiens	151-157
33408644-5	2020	Glycine acts on one-cell and cleavage-stage mouse embryos through the glycine-gated chloride channel, GLRA4, and uptake via the glycine neurotransmitter transporter, GLYT1.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	166-171
33408644-5	2020	Glycine acts on one-cell and cleavage-stage mouse embryos through the glycine-gated chloride channel, GLRA4, and uptake via the glycine neurotransmitter transporter, GLYT1.	Glycine	128-135	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	166-171
33322577-5	2020	This was associated with a compensatory increase in hippocampal levels of glycine, another physiologic NMDAR co-agonist.	Glycine	74-81	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	103-108
32915994-6	2020	RNA-seq analysis using the Gly-rich domain-deleted mutant coupled with snRNP70 knockdown revealed that FUS has a potential to regulate gene expression in both snRNP70-dependent and -independent manners through the Gly-rich domain.	Glycine	27-30	small nuclear ribonucleoprotein U1 subunit 70	Homo sapiens	159-166
33122756-3	2020	We found that the S688Y mutation significantly increases the EC50 of both glycine and D-serine in GluN1/GluN2A and GluN1/GluN2B receptors, and significantly slows desensitisation of GluN1/GluN3A receptors.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	188-194
33194080-0	2020	Glycine attenuates cerebrovascular remodeling via glycine receptor alpha 2 and vascular endothelial growth factor receptor 2 after stroke.	Glycine	0-7	glycine receptor, alpha 2	Rattus norvegicus	50-74
33194080-0	2020	Glycine attenuates cerebrovascular remodeling via glycine receptor alpha 2 and vascular endothelial growth factor receptor 2 after stroke.	Glycine	0-7	kinase insert domain receptor	Rattus norvegicus	79-124
32378271-7	2020	In addition, immunohistochemical studies corroborate the present findings suggestingthat 5-HT1A receptors are widely expressed in close apposition to the soma of glycine-immunoreactive cells located within the pTRG region.	Glycine	162-169	5-hydroxytryptamine receptor 1A	Homo sapiens	89-95
33101846-5	2020	It is shown that FOXO4 directly binds and suppresses the promoters of serine-glycine-one-carbon (SGOC) pathway genes, thereby diminishing SGOC metabolism.	Glycine	77-84	forkhead box O4	Homo sapiens	17-22
33101846-7	2020	Thus, these data suggest a link of CSN6-FOXO4 axis and ser/gly metabolism.	Glycine	59-62	forkhead box O4	Homo sapiens	40-45
33101846-9	2020	The results illustrate a pathway regulation of FOXO4-mediated serine/glycine metabolism through the function of CSN6-COP1 axis.	Glycine	69-76	forkhead box O4	Homo sapiens	47-52
32626969-3	2020	Autophagy-related gene 4a (ATG4a) cleaves autophagy-related protein 8 (Atg8) near the C terminus, allowing Atg8 to conjugate with phosphatidylethanolamine via the exposed glycine; although this is pivotal in cancer development, no study has yet linked it to eye diseases.	Glycine	171-178	autophagy related 4A cysteine peptidase	Homo sapiens	27-32
32577860-3	2020	Glycine at position 311 of Kv1.1 is highly conserved both evolutionarily and within the Kv channel superfamily, is located in a region functionally relevant (the S4-S5 linker), and results in overt disease when mutated (p.G311D).	Glycine	0-7	potassium voltage-gated channel subfamily A member 1	Homo sapiens	27-32
32142918-8	2020	Similar to its family member SHMT2, SHMT1 plays a crucial role in folate-dependent serine/glycine inter-conversion in one-carbon metabolism.	Glycine	90-97	serine hydroxymethyltransferase 1	Homo sapiens	36-41
32546967-0	2020	Glycine Improves Ischemic Stroke Through miR-19a-3p/AMPK/GSK-3beta/HO-1 Pathway.	Glycine	0-7	heme oxygenase 1	Homo sapiens	67-71
32546967-14	2020	Rescue experiments demonstrated that glycine improved cell apoptosis, inflammatory response and glucose metabolism disorder of ischemic stroke through miR-19a-3p/AMPK/GSK-3beta/HO-1 pathway.	Glycine	37-44	heme oxygenase 1	Homo sapiens	177-181
32546967-15	2020	Conclusion: Glycine improves ischemic stroke through miR-19a-3p/AMPK/GSK-3beta/HO-1 pathway.	Glycine	12-19	heme oxygenase 1	Homo sapiens	79-83
32317281-6	2020	A SNAP25 mutant in which the mini-linker region was substituted with a flexible glycine-serine linker of the same length underwent efficient S-acylation.	Glycine	80-87	synaptosome associated protein 25	Homo sapiens	2-8
31859406-2	2020	We used a fluorescence quenching assay and isothermal titration calorimetry to record low micromolar dissociation constants for N-methylbicuculline interacting with acetylcholine binding protein and an engineered version called glycine-binding protein (GBP), which provides a surrogate for the heteromeric interface of the extracellular domain of the glycine receptor (GlyR).	Glycine	228-235	transmembrane protein 132A	Homo sapiens	253-256
4008049-5	1985	The first 10 amino-terminal amino acid residues of the cytolysin are Phe-Thr-Gln-Trp-Gly-Gly-Ser-Gly-Leu-Thr.	Glycine	85-88	perforin 1 (pore forming protein)	Mus musculus	55-64
4008049-5	1985	The first 10 amino-terminal amino acid residues of the cytolysin are Phe-Thr-Gln-Trp-Gly-Gly-Ser-Gly-Leu-Thr.	Glycine	89-92	perforin 1 (pore forming protein)	Mus musculus	55-64
4008049-5	1985	The first 10 amino-terminal amino acid residues of the cytolysin are Phe-Thr-Gln-Trp-Gly-Gly-Ser-Gly-Leu-Thr.	Glycine	89-92	perforin 1 (pore forming protein)	Mus musculus	55-64
3838667-1	1985	Glycine N-methyltransferase, an enzyme that uses S-adenosylmethionine to methylate glycine with the production of sarcosine, was recently shown to be identical with a major folate binding protein of rat liver (Cook, R.J. and Wagner, C. (1984) Proc.	Glycine	83-90	glycine N-methyltransferase	Rattus norvegicus	0-27
3995160-3	1985	For the specific activation, a chromatographic separation of, e.g. ala and CMP from gly and GMP can be accomplished on silica (e.g. of volcanic origin) with aqueous salt solutions.	Glycine	84-87	matrilin 1	Homo sapiens	75-78
6096811-2	1984	The oncogene of PR371 was found to present a mutation at codon 12 of the first coding exon which substitutes cysteine for glycine in the encoded p21 protein.	Glycine	122-129	H3 histone pseudogene 16	Homo sapiens	145-148
6089200-3	1984	This results in substitution of aspartic acid for glycine at this position of the p21 coding sequence.	Glycine	50-57	H3 histone pseudogene 16	Homo sapiens	82-85
6537044-1	1984	The glycine conjugate of 3 beta-hydroxy-5-cholen-24-oic acid and its sulfate labeled with deuterium at the C-2, -4, and -23 positions were synthesized.	Glycine	4-11	complement C2	Homo sapiens	107-123
6147868-2	1984	The enzyme serine hydroxymethyltransferase (SHMT), which metabolizes serine to glycine, showed abnormal activity in the psychotics compared to nonpsychotics and controls.	Glycine	79-86	serine hydroxymethyltransferase 1	Homo sapiens	11-42
6147868-2	1984	The enzyme serine hydroxymethyltransferase (SHMT), which metabolizes serine to glycine, showed abnormal activity in the psychotics compared to nonpsychotics and controls.	Glycine	79-86	serine hydroxymethyltransferase 1	Homo sapiens	44-48
6723969-2	1984	Stimulation of human milk lipase by deoxycholate and its taurine and glycine conjugates was demonstrated by measuring the esterolysis reaction of 4-nitrophenylacetate.	Glycine	69-76	carboxyl ester lipase	Homo sapiens	21-32
6323443-5	1984	Automated Edman degradation of a tryptic peptide containing radioactive carboxamidomethylcysteine showed the sequence of residues Gly-111-Arg-140 of pig kidney fructose 1,6-bisphosphatase.	Glycine	130-133	fructose-bisphosphatase 1	Sus scrofa	160-187
2405382-1	1990	Covalent linkage of myristic acid to the N-terminal glycine residue of Pr55gag, the precursor of the major structural proteins of human immunodeficiency virus 1 (HIV-1), facilitates an essential step in virus assembly and propagation.	Glycine	52-59	Pr55(Gag)	Human immunodeficiency virus 1	71-78
6497542-0	1984	[Serum gastrin level before and after gastrectomy following oral administration of glycine].	Glycine	83-90	gastrin	Homo sapiens	7-14
16593407-5	1984	The tRNA(Gly) and tRNA(Arg) deduced from the DNA sequences show 84% and 55% sequence homologies with Escherichia coli tRNA(Gly) (UCC) and phage T4 tRNA(Arg) (UCU), respectively.	Glycine	123-126	trnY(gua)	Nicotiana tabacum	4-8
16593407-5	1984	The tRNA(Gly) and tRNA(Arg) deduced from the DNA sequences show 84% and 55% sequence homologies with Escherichia coli tRNA(Gly) (UCC) and phage T4 tRNA(Arg) (UCU), respectively.	Glycine	123-126	trnY(gua)	Nicotiana tabacum	18-22
16593407-5	1984	The tRNA(Gly) and tRNA(Arg) deduced from the DNA sequences show 84% and 55% sequence homologies with Escherichia coli tRNA(Gly) (UCC) and phage T4 tRNA(Arg) (UCU), respectively.	Glycine	123-126	trnY(gua)	Nicotiana tabacum	18-22
32085975-2	2020	AS is attributed to mutations in type IV collagen genes, particularly glycine missense mutations in the collagenous domain of COL4A5 that disrupt common structural motifs in collagen from the repeat (Gly-Xaa-Yaa)n amino acid sequence.	Glycine	70-77	collagen type IV alpha 5 chain	Homo sapiens	126-132
32277103-10	2020	Importantly, higher [1-13C]glycine was associated with higher GGT expression and higher GSH levels in tumor tissue compared to normal brain.	Glycine	27-34	gamma-glutamyltransferase 1	Rattus norvegicus	62-65
25963836-16	2015	The addition of the glycine residue to the peptide, as in the case of MUC1-G, is shown to yield a stable binding.	Glycine	20-27	mucin 1, cell surface associated	Homo sapiens	70-74
32113649-3	2020	In IWC-I, the mutations lead to replacement of glycine/serine-rich keratin 10 (K10) tail with arginine- or alanine-rich frameshift motifs, causing K10 mis-localization which might trigger loss of the mutant KRT10 allele via mitotic recombination, leading to genetic reversion.	Glycine	47-54	keratin 10	Homo sapiens	79-82
32113649-3	2020	In IWC-I, the mutations lead to replacement of glycine/serine-rich keratin 10 (K10) tail with arginine- or alanine-rich frameshift motifs, causing K10 mis-localization which might trigger loss of the mutant KRT10 allele via mitotic recombination, leading to genetic reversion.	Glycine	47-54	keratin 10	Homo sapiens	147-150
32113649-3	2020	In IWC-I, the mutations lead to replacement of glycine/serine-rich keratin 10 (K10) tail with arginine- or alanine-rich frameshift motifs, causing K10 mis-localization which might trigger loss of the mutant KRT10 allele via mitotic recombination, leading to genetic reversion.	Glycine	47-54	keratin 10	Homo sapiens	207-212
6139154-6	1983	The excitatory effect of phoretically administered L-glutamate as well as synaptically induced and spontaneous activity was reduced or abolished by phoretically administered GABA, glycine or the enkephalin-analogue D-Ala2-D-Leu5-enkephalin.	Glycine	180-187	proenkephalin	Rattus norvegicus	229-239
6415068-5	1983	YL 1/2 reacts with the synthetic peptide Gly-(Glu)3-Gly-(Glu)2-Tyr, corresponding to the carboxyterminal amino acid sequence of tyrosylated alpha-tubulin, but does not react with Gly-(Glu)3-Gly-(Glu)2, the constituent peptide of detyrosylated alpha-tubulin.	Glycine	41-44	vacuolar protein sorting 72 homolog	Homo sapiens	0-4
6415068-5	1983	YL 1/2 reacts with the synthetic peptide Gly-(Glu)3-Gly-(Glu)2-Tyr, corresponding to the carboxyterminal amino acid sequence of tyrosylated alpha-tubulin, but does not react with Gly-(Glu)3-Gly-(Glu)2, the constituent peptide of detyrosylated alpha-tubulin.	Glycine	52-55	vacuolar protein sorting 72 homolog	Homo sapiens	0-4
34977370-9	2022	In summary, our results indicated that glycine alleviates ER stress-induced apoptosis and intestinal barrier dysfunction in IPEC-1 cells in a mammalian target of rapamycin complex 1 (mTORC1)-dependent manner.	Glycine	39-46	CREB regulated transcription coactivator 1	Mus musculus	183-189
6577419-4	1983	The calculations show that the most favorable form of the c-Ha ras-1 gene product exists when glycine-12 is in a left-handed bend conformation.	Glycine	94-101	HRas proto-oncogene, GTPase	Homo sapiens	58-68
30909811-5	2020	These include ubiquitous contact between glycines in the oxyanion hole and the inhibitor phosphate group; a sterically driven binding preference for positional isomers that extend aromaticity; a stereochemical binding preference for choline-containing inhibitors, which mimic natural BChE substrates; and the mechanically induced opening of the omega loop region to fully expose the active site gorge in the presence of choline-containing inhibitors.	Glycine	41-49	butyrylcholinesterase	Homo sapiens	284-288
34890750-3	2022	Keratin 1 (K1) is a type II keratin whose structure is comprised of a coiled-coil central domain flanked by flexible, glycine-rich loops in the N- and C-termini.	Glycine	118-125	keratin 1	Homo sapiens	0-9
31746479-2	2020	Comparison of WGS identified a variant in residue 558 of the transmembrane domain (TM) of TSHR, where the domestic chicken (GGD) presents an arginine, whereas the red jungle fowl (RJF) shares a conserved glycine with other vertebrates.	Glycine	204-211	thyroid stimulating hormone receptor	Gallus gallus	90-94
6843652-3	1983	Sequence data of retroviral analogues of the p21 protein also indicate the importance for a glycine residue at position 12 in normal p21.	Glycine	92-99	H3 histone pseudogene 16	Homo sapiens	45-48
6843652-3	1983	Sequence data of retroviral analogues of the p21 protein also indicate the importance for a glycine residue at position 12 in normal p21.	Glycine	92-99	H3 histone pseudogene 16	Homo sapiens	133-136
6843652-5	1983	We present here a three-dimensional model of the p21 beta alpha beta unit which explains directly why glycine at position 12 cannot be replaced by another residue without altering the nucleotide-binding properties of p21.	Glycine	102-109	H3 histone pseudogene 16	Homo sapiens	49-52
34525858-3	2021	Besides, similar to PBA, D4F inhibited gly-HDL-induced ER stress response activation evaluated through the decreased PERK and eIF2alpha phosphorylation, together with reduced ATF6 nuclear translocation as well as the downregulation of GRP78 and CHOP.	Glycine	39-42	eukaryotic translation initiation factor 2A	Mus musculus	126-135
6311615-2	1983	A tridecapeptide: Arg-Arg-Leu56-Asp-Thr-Thr59-Gly-Gln-Glu-Tyr-Ser-Ala66 containing residues 56-66 of p21 is phosphorylated solely on tyrosine by the epidermal growth factor (EGF)-stimulated tyrosine kinase of A431 cell membranes.	Glycine	46-49	H3 histone pseudogene 16	Homo sapiens	101-104
31677233-1	2020	HLA-B*52:01:24 has one synonymous nucleotide change from HLA-B*52:01:01:01 at nucleotide 384 (codon 104 Glycine).	Glycine	104-111	major histocompatibility complex, class I, B	Homo sapiens	0-5
31677233-1	2020	HLA-B*52:01:24 has one synonymous nucleotide change from HLA-B*52:01:01:01 at nucleotide 384 (codon 104 Glycine).	Glycine	104-111	major histocompatibility complex, class I, B	Homo sapiens	57-62
6311615-2	1983	A tridecapeptide: Arg-Arg-Leu56-Asp-Thr-Thr59-Gly-Gln-Glu-Tyr-Ser-Ala66 containing residues 56-66 of p21 is phosphorylated solely on tyrosine by the epidermal growth factor (EGF)-stimulated tyrosine kinase of A431 cell membranes.	Glycine	46-49	epidermal growth factor	Homo sapiens	174-177
34525858-3	2021	Besides, similar to PBA, D4F inhibited gly-HDL-induced ER stress response activation evaluated through the decreased PERK and eIF2alpha phosphorylation, together with reduced ATF6 nuclear translocation as well as the downregulation of GRP78 and CHOP.	Glycine	39-42	activating transcription factor 6	Mus musculus	175-179
34525858-4	2021	Interestingly, D4F facilitated gly-HDL-triggered activation of autophagy, measured as elevated levels of beclin-1, LC3-II, and ATG5 expressions in macrophages.	Glycine	31-34	autophagy related 5	Mus musculus	127-131
6679320-3	1983	Further studies on the glycine-14CO2 exchange catalyzed by p-protein and H-protein purified from chicken liver indicated that tiglyl CoA inhibited the activity of P-protein in an apparently competitive manner with respect to H-protein, and that cysteamine inhibited the activity of P-protein in two ways, by increasing the Km value for glycine and changing Vmax.	Glycine	23-30	OCA2 melanosomal transmembrane protein	Gallus gallus	59-68
34917610-10	2021	Moreover, we found that the increase in (Ca2+)i may be caused by changes in the distribution and expression of inositol 1,4,5-triphosphate receptor (IP3R1) and voltage-dependent anion channel 1 (VDAC1), while Gly can restore the distribution and expression of IP3R1 and VDAC1 to normal levels.	Glycine	209-212	voltage dependent anion channel 1	Homo sapiens	270-275
34734802-8	2021	Substitution of this glycine with alanine, a residue conserved in BTLA and several SHP1-recruiting receptors, was sufficient to induce PD-1:SHP1 interaction in T cells.	Glycine	21-28	nuclear receptor subfamily 0 group B member 2	Homo sapiens	83-87
34734802-8	2021	Substitution of this glycine with alanine, a residue conserved in BTLA and several SHP1-recruiting receptors, was sufficient to induce PD-1:SHP1 interaction in T cells.	Glycine	21-28	nuclear receptor subfamily 0 group B member 2	Homo sapiens	140-144
6301756-2	1983	The pathogenesis of the biochemical defect leading to increased glycine concentration in blood, urine, and CSF is likely to concern derangements of the glycine cleavage enzyme and/or transport mechanisms of glycine.	Glycine	152-159	colony stimulating factor 2	Homo sapiens	107-110
6301756-2	1983	The pathogenesis of the biochemical defect leading to increased glycine concentration in blood, urine, and CSF is likely to concern derangements of the glycine cleavage enzyme and/or transport mechanisms of glycine.	Glycine	152-159	colony stimulating factor 2	Homo sapiens	107-110
31985312-3	2021	DNA sequencing showed a mutation of codon 46 and it was named Hb Cenxi [beta46(CD5)Gly Arg (GGG>CGG), HBB: c.139G>C] for the city of birth of the proband.	Glycine	83-86	CD5 molecule	Homo sapiens	79-82
34662099-7	2021	For example, the replacement of the glutamic acid side with a glycine chain at position 305 in the CYP17A1 structure causes a clinically relevant steroidopathy; E305G CYP17A1 displays a dramatic decrease in the production of dehydroepiandrosterone from pregnenolone but surprisingly increases the activity of the enzyme toward the formation of androstenedione from progesterone.	Glycine	62-69	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	99-106
31487503-10	2019	Together, this study provides first evidence that the carboxyl-terminal region of KIF13B containing the CAP-Gly domain is important for the LRP1-DLG1-KIF13B complex formation with implications in the regulation of metabolism, cell polarity, and development.	Glycine	108-111	discs large MAGUK scaffold protein 1	Mus musculus	145-149
31549830-1	2019	The coupled cluster models CCSD and CC3 are used to investigate the (core) excited states and ionization energies of glycine in the gas phase.	Glycine	117-124	C-C motif chemokine ligand 14	Homo sapiens	36-39
6363850-1	1983	It is generally assumed that enkephalinase A, a highly thiorphan-sensitive dipeptidylcarboxypeptidase cleaving the Gly-Phe bond during enkephalin degradation, is bound to the neuronal membrane.	Glycine	115-118	proenkephalin	Rattus norvegicus	29-39
34662099-7	2021	For example, the replacement of the glutamic acid side with a glycine chain at position 305 in the CYP17A1 structure causes a clinically relevant steroidopathy; E305G CYP17A1 displays a dramatic decrease in the production of dehydroepiandrosterone from pregnenolone but surprisingly increases the activity of the enzyme toward the formation of androstenedione from progesterone.	Glycine	62-69	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	167-174
6293568-3	1982	Liberation of glycine was inhibited (74-83%) by serine borate (20 mM), indicating a gamma-glutamyltransferase-dependent hydrolysis of GSH.	Glycine	14-21	gamma-glutamyltransferase 1	Rattus norvegicus	84-109
31653780-4	2019	We replaced two distinct, but conserved, glycines in both the Dictyostelium piaA gene and its human ortholog, rictor The two conserved residues are spaced by approximately 50 aminoacids and both are embedded within a conserved region falling in between the Ras-GEFN2 and Rictor_V domains.	Glycine	41-49	RPTOR independent companion of MTOR complex 2	Homo sapiens	110-116
34757085-5	2022	Then, in the ventral horn, microglia were activated, and expression of choline acetyltransferase (ChAT), a synthetic enzyme of acetylcholine, and potassium chloride co-transporter 2 (KCC2), which shifts the action of gamma-amino butyric acid (GABA) and glycine to inhibitory, decreased.	Glycine	253-260	choline acetyltransferase	Mus musculus	71-96
31541001-1	2019	The potassium-chloride cotransporter (KCC2) maintains the low intracellular chloride found in mature central neurons and controls the strength and direction of GABA/glycine synapses.	Glycine	165-172	solute carrier family 12, member 5	Mus musculus	38-42
7133135-2	1982	This substitution results in the incorporation of valine instead of glycine as the twelfth amino acid residue of the T24 oncogene-encoded p21 protein.	Glycine	68-75	H3 histone pseudogene 16	Homo sapiens	138-141
34757085-5	2022	Then, in the ventral horn, microglia were activated, and expression of choline acetyltransferase (ChAT), a synthetic enzyme of acetylcholine, and potassium chloride co-transporter 2 (KCC2), which shifts the action of gamma-amino butyric acid (GABA) and glycine to inhibitory, decreased.	Glycine	253-260	choline acetyltransferase	Mus musculus	98-102
34827083-0	2021	Abnormal Enhancement of Protein Disulfide Isomerase-like Activity of a Cyclic Diselenide Conjugated with a Basic Amino Acid by Inserting a Glycine Spacer.	Glycine	139-146	prolyl 4-hydroxylase subunit beta	Homo sapiens	24-51
7053363-0	1982	Purification and characterization of chicken liver T-protein, a component of the glycine cleavage system.	Glycine	81-88	aminomethyltransferase	Gallus gallus	51-60
7053363-1	1982	T-protein, a component of the glycine cleavage system, has been purified to apparent homogeneity from chicken liver mitochondria.	Glycine	30-37	aminomethyltransferase	Gallus gallus	0-9
31581160-1	2019	BACKGROUND Serine hydroxymethyltransferase (SHMT) is the enzyme that catalyzes the reversible conversion of serine to glycine and tetrahydrofolate-bound one-carbon unit.	Glycine	118-125	serine hydroxymethyltransferase 1	Homo sapiens	11-42
31581160-1	2019	BACKGROUND Serine hydroxymethyltransferase (SHMT) is the enzyme that catalyzes the reversible conversion of serine to glycine and tetrahydrofolate-bound one-carbon unit.	Glycine	118-125	serine hydroxymethyltransferase 1	Homo sapiens	44-48
34827083-3	2021	Exhaustive comparison of the PDI-like catalytic activities and E"  values among 1, 1-Xaa, and 1-Gly-Xaa showed that the insertion of a Gly spacer into 1-Xaa either did not change or slightly reduced the PDI-like activity and the E"  values.	Glycine	135-138	prolyl 4-hydroxylase subunit beta	Homo sapiens	29-32
34827083-3	2021	Exhaustive comparison of the PDI-like catalytic activities and E"  values among 1, 1-Xaa, and 1-Gly-Xaa showed that the insertion of a Gly spacer into 1-Xaa either did not change or slightly reduced the PDI-like activity and the E"  values.	Glycine	135-138	prolyl 4-hydroxylase subunit beta	Homo sapiens	203-206
34692814-16	2021	The findings from this meta-analysis indicate that not only soluble fiber, but also increasing levels of dietary fat and protein may result in greater fecal excretion of BA, potentially altering taurine and/or glycine metabolism and affecting the need for diet delivery of these AA.	Glycine	210-217	FAT atypical cadherin 1	Rattus norvegicus	113-116
31552033-4	2019	In our recent work, we identified several hepatitis E virus (HEV)-specific TCRs as potential candidates to be developed into T cell therapy to treat chronic hepatitis E. One of the identified TCRs, targeting a HLA-A2-restricted epitope at the RNA-dependent RNA polymerase (HEV-1527: LLWNTVWNM), possessed a unique multiple glycine motif in the TCR-beta CDR3, which might be a factor inducing cross-reactivity.	Glycine	323-330	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	75-78
31552033-8	2019	The consecutive glycine motif in beta chain may be the reason promoting TCR binding promiscuity to recognize a secondary target, thereby facilitating cross-recognition.	Glycine	16-23	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	72-75
7291041-2	1981	Purified enzyme was devoid of contamination of tryptic-like enzymes, by dipeptidyl carboxypeptidase (angiotensin converting enzyme) and of enkephalinnases cleaving the Tyr-Gly and Gly-Phe bonds of Met-enkephalin.	Glycine	172-175	proenkephalin	Rattus norvegicus	139-149
7019446-1	1981	Metabolic breakdown of the luteinizing hormone-releasing hormone (LH-RH) could lead to the following fragments containing pyroglutamic acid: pyroglutamic acid (1), pGlu-His (2), pGLu-His-Trp (3), pGlu-His-Trp-Ser (4), etc., and finally pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly (10).	Glycine	257-260	gonadotropin releasing hormone 1	Rattus norvegicus	27-64
34484166-4	2021	The novel bla KPC-74 variant showed a deletion of 6 nucleotides at positions 712-717 compared with bla KPC-2, and this deletion resulted in the consequent deletion of glycine and valine at positions 239 and 240.	Glycine	167-174	UBA domain containing 1	Homo sapiens	103-108
7019446-1	1981	Metabolic breakdown of the luteinizing hormone-releasing hormone (LH-RH) could lead to the following fragments containing pyroglutamic acid: pyroglutamic acid (1), pGlu-His (2), pGLu-His-Trp (3), pGlu-His-Trp-Ser (4), etc., and finally pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly (10).	Glycine	257-260	gonadotropin releasing hormone 1	Rattus norvegicus	66-71
7019446-1	1981	Metabolic breakdown of the luteinizing hormone-releasing hormone (LH-RH) could lead to the following fragments containing pyroglutamic acid: pyroglutamic acid (1), pGlu-His (2), pGLu-His-Trp (3), pGlu-His-Trp-Ser (4), etc., and finally pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly (10).	Glycine	273-276	gonadotropin releasing hormone 1	Rattus norvegicus	27-64
7019446-1	1981	Metabolic breakdown of the luteinizing hormone-releasing hormone (LH-RH) could lead to the following fragments containing pyroglutamic acid: pyroglutamic acid (1), pGlu-His (2), pGLu-His-Trp (3), pGlu-His-Trp-Ser (4), etc., and finally pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly (10).	Glycine	273-276	gonadotropin releasing hormone 1	Rattus norvegicus	66-71
7225408-2	1981	Solutions of different ratios of alpha 1 and alpha 2 chains, one of which was labelled with [14C]- or [3H]glycine, were renatured to form triple-helical, rod-shaped molecules, then cross-linked intramolecularly with formaldehyde.	Glycine	106-113	adrenoceptor alpha 1D	Homo sapiens	33-52
7448810-7	1981	Glycine- or taurine-conjugated deoxycholate showed ODC and SAMD enzyme activations similar to that of nonconjugated deoxycholate.	Glycine	0-7	ornithine decarboxylase 1	Rattus norvegicus	51-54
6966584-1	1980	The C-terminal amino acid sequences of human and of porcine antithrombin III have been determined as Gly-Arg-Val-Ala-Asn-Pro-Cys-Val-Lys and Gly-Arg-Val-Ala-Asn-Pro-Cys, respectively.	Glycine	101-104	serpin family C member 1	Homo sapiens	60-76
6106548-1	1980	Glutathione is synthesized from gamma-glutamylcysteine and glycine via the action of glutathione synthetase.	Glycine	59-66	glutathione synthetase	Homo sapiens	85-107
315708-8	1979	The amino acid substitution, Gly to Asp, has been found in a common PiM2 variant [1].	Glycine	29-32	Pim-2 proto-oncogene, serine/threonine kinase	Homo sapiens	68-72
315708-9	1979	The Pi B Alhambra variant presumably originated by two steps of mutation: generation of PiM2 from wild type PiM1 by the substitution Gly to Asp, and subsequent generation of Pi B Alhambra from PiM2 by another substitution, Lys to Asp.	Glycine	133-136	Pim-2 proto-oncogene, serine/threonine kinase	Homo sapiens	88-92
583064-7	1979	Elevated CSF glycine seems to be the essential determinant of the neurological disturbances and it is, therefore, suggested that the term glycine encephalopathy be used instead of non-ketotic hyperglycinemia.	Glycine	13-20	colony stimulating factor 2	Homo sapiens	9-12
583064-7	1979	Elevated CSF glycine seems to be the essential determinant of the neurological disturbances and it is, therefore, suggested that the term glycine encephalopathy be used instead of non-ketotic hyperglycinemia.	Glycine	138-145	colony stimulating factor 2	Homo sapiens	9-12
220234-4	1979	Specific activities of the iso-1-cytochromes c were estimated by growth of strains on lactate medium and are as follows, in terms of the normal, for iso-1-cytochromes c altered specifically in the ways shown: 100% for phenylalanine 64; 25% for tyrosine 64; between 0 and 25% for leucine 64; 100% for phenylalanine 45, cysteine 64; 25% for phenylalanine 45, serine 64; between 0 and 25% for phenylalanine 45, glycine 64, alanine 65; and 0% for serine 64, for cysteine 64, and for glycine 64, alanine 65 iso-1-cytochromes c. The results demonstrate that small residues of glycine, serine, and cysteine at position 64 are incompatible with function; they imply that many of the 10 amino acids accessible by single base-pair substitution but not observed in primary site revertants also are incompatible with function; and they show that large hydrophobic residues of phenylalanine, leucine, and tyrosine at position 64 are capable of restoring at least partial function.	Glycine	408-415	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	27-32
220234-4	1979	Specific activities of the iso-1-cytochromes c were estimated by growth of strains on lactate medium and are as follows, in terms of the normal, for iso-1-cytochromes c altered specifically in the ways shown: 100% for phenylalanine 64; 25% for tyrosine 64; between 0 and 25% for leucine 64; 100% for phenylalanine 45, cysteine 64; 25% for phenylalanine 45, serine 64; between 0 and 25% for phenylalanine 45, glycine 64, alanine 65; and 0% for serine 64, for cysteine 64, and for glycine 64, alanine 65 iso-1-cytochromes c. The results demonstrate that small residues of glycine, serine, and cysteine at position 64 are incompatible with function; they imply that many of the 10 amino acids accessible by single base-pair substitution but not observed in primary site revertants also are incompatible with function; and they show that large hydrophobic residues of phenylalanine, leucine, and tyrosine at position 64 are capable of restoring at least partial function.	Glycine	408-415	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	149-154
220234-4	1979	Specific activities of the iso-1-cytochromes c were estimated by growth of strains on lactate medium and are as follows, in terms of the normal, for iso-1-cytochromes c altered specifically in the ways shown: 100% for phenylalanine 64; 25% for tyrosine 64; between 0 and 25% for leucine 64; 100% for phenylalanine 45, cysteine 64; 25% for phenylalanine 45, serine 64; between 0 and 25% for phenylalanine 45, glycine 64, alanine 65; and 0% for serine 64, for cysteine 64, and for glycine 64, alanine 65 iso-1-cytochromes c. The results demonstrate that small residues of glycine, serine, and cysteine at position 64 are incompatible with function; they imply that many of the 10 amino acids accessible by single base-pair substitution but not observed in primary site revertants also are incompatible with function; and they show that large hydrophobic residues of phenylalanine, leucine, and tyrosine at position 64 are capable of restoring at least partial function.	Glycine	408-415	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	149-154
36154-1	1979	The chlorination of glycine by the myeloperoxidase-H2O2-Cl- system at acidic pH values yielded N-monochloroglycine and a mixture of HCN and ClCN.	Glycine	20-27	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	132-135
427211-7	1979	Its sequence (Gly-Ala-Glu-allysine-(Glu)...) and amino acid composition suggest: (1) clustering of glutamic acid residues in the elastin molecule, and (2) that allysine residues are not restricted to the alanine-enriched sites described for other elastin cross-links.	Glycine	14-17	LOC100620140	Sus scrofa	129-136
378806-4	1979	These findings indicate that increased activity of the analogues may, in part be due to increased resistance to enzymic inactivation and suggest initial sites of cleavage at the Gly-leu and Pro-Gly NH2 bonds in the LH-RH decapeptide by the hypothalamic enzymes.	Glycine	178-181	gonadotropin releasing hormone 1	Rattus norvegicus	215-220
378806-4	1979	These findings indicate that increased activity of the analogues may, in part be due to increased resistance to enzymic inactivation and suggest initial sites of cleavage at the Gly-leu and Pro-Gly NH2 bonds in the LH-RH decapeptide by the hypothalamic enzymes.	Glycine	194-197	gonadotropin releasing hormone 1	Rattus norvegicus	215-220
561911-4	1977	In the other case, increased CSF glycine was implicated.	Glycine	33-40	colony stimulating factor 2	Homo sapiens	29-32
913715-0	1977	[Increases of serum gastrin and growth hormone concentrations in subjects suffering from hyperthyroidism, hypothyroidism, and in patients with partial gastrectomy, and normal subjects in the per-oral administration of glycine].	Glycine	218-225	gastrin	Homo sapiens	20-27
832136-2	1977	Quaking mice and littermate controls received intracranial injections of 150 muCi [3H]glycine and 25 muCi of [14C]glycine respectively.	Glycine	86-93	quaking, KH domain containing RNA binding	Mus musculus	0-7
832136-2	1977	Quaking mice and littermate controls received intracranial injections of 150 muCi [3H]glycine and 25 muCi of [14C]glycine respectively.	Glycine	114-121	quaking, KH domain containing RNA binding	Mus musculus	0-7
832136-4	1977	The 3H/14C ratio for the myelin subfraction was 1.88 as compared to a 3H/14C ratio of 3.0 for the other subfractions, indicating a 40% decrease in glycine incorporation into myelin of Quaking mice.	Glycine	147-154	quaking, KH domain containing RNA binding	Mus musculus	184-191
832136-7	1977	During development, the Quaking mutant exhibited a preferential depression in glycine incorporation into proteolipid protein in 18-day-old mice, while in older animals (32-54 days) the fast migrating basic protein, as well as the proteolipid protein, was labeled to a significantly lesser extent.	Glycine	78-85	quaking, KH domain containing RNA binding	Mus musculus	24-31
907224-4	1977	The high levels of glycine found in CSF and brain are likely to reflect the brain damage.	Glycine	19-26	colony stimulating factor 2	Homo sapiens	36-39
12509-3	1976	The uptake of glycine was also Na+ gradient dependent, and exhibited a two Km system, Km1 = 0.22 mM and Km2 = 4.00 mM.	Glycine	14-21	Kidney mass QTL 1	Rattus norvegicus	86-89
992944-1	1976	Tertiary structures of gastrin-like tetrapeptide Trp-Met-Asp-Phe-NH2 and those substituted by Leu, Val or Gly for Met are studied.	Glycine	106-109	gastrin	Homo sapiens	23-30
4741541-0	1973	Glycine activation of PEP carboxylase from monocotyledoneous C4 plants.	Glycine	0-7	progestagen associated endometrial protein	Homo sapiens	22-25
5013353-2	1972	Glycine NCA.	Glycine	0-7	CEA cell adhesion molecule 6	Homo sapiens	8-11
4333378-2	1972	Two serine-glycine auxotrophs (ser1 and ser2) were found to be blocked in the phosphoglycerate pathway.	Glycine	11-18	O-phospho-L-serine:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	31-35
4333378-2	1972	Two serine-glycine auxotrophs (ser1 and ser2) were found to be blocked in the phosphoglycerate pathway.	Glycine	11-18	phosphoserine phosphatase	Saccharomyces cerevisiae S288C	40-44
5545117-6	1971	Glutathione synthetase requires gamma-glutamyl cysteine, glycine, ATP, and magnesium ions to form glutathione.	Glycine	57-64	glutathione synthetase	Homo sapiens	0-22
30734226-4	2019	Incubation of synaptosomes with the anti-GluN1, the anti-GluN2A, the anti-GluN2B, or the anti-GluN3A antibody prevented the 30 muM NMDA/1 muM glycine-evoked [3H]D-aspartate ([3H]D-ASP) release.	Glycine	142-149	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	41-46
30734226-4	2019	Incubation of synaptosomes with the anti-GluN1, the anti-GluN2A, the anti-GluN2B, or the anti-GluN3A antibody prevented the 30 muM NMDA/1 muM glycine-evoked [3H]D-aspartate ([3H]D-ASP) release.	Glycine	142-149	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	Mus musculus	57-63
30734226-4	2019	Incubation of synaptosomes with the anti-GluN1, the anti-GluN2A, the anti-GluN2B, or the anti-GluN3A antibody prevented the 30 muM NMDA/1 muM glycine-evoked [3H]D-aspartate ([3H]D-ASP) release.	Glycine	142-149	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	74-80
30734226-5	2019	The NMDA/glycine-evoked [3H]D-ASP release was reduced by increasing the external protons, consistent with the participation of GluN1 subunits lacking the N1 cassette to the receptor assembly.	Glycine	9-16	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	127-132
31005058-3	2019	Our studies in mice reveal that an activation of substance P-positive dorsomedial habenula (dMHb) neurons results in simultaneous release of glutamate and glycine in the lateral interpeduncular nucleus (LIPN).	Glycine	155-162	tachykinin 1	Mus musculus	49-60
32003208-11	2019	At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p <0.01), Gly/ Arg - 9.9% (p <0.01) and Arg/Arg - 3.3% (p <0.05).	Glycine	91-94	insulin receptor substrate 1	Homo sapiens	74-79
32003208-11	2019	At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p <0.01), Gly/ Arg - 9.9% (p <0.01) and Arg/Arg - 3.3% (p <0.05).	Glycine	95-98	insulin receptor substrate 1	Homo sapiens	74-79
32003208-11	2019	At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p <0.01), Gly/ Arg - 9.9% (p <0.01) and Arg/Arg - 3.3% (p <0.05).	Glycine	95-98	insulin receptor substrate 1	Homo sapiens	74-79
32003208-11	2019	At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p <0.01), Gly/ Arg - 9.9% (p <0.01) and Arg/Arg - 3.3% (p <0.05).	Glycine	95-98	insulin receptor substrate 1	Homo sapiens	74-79
31444392-0	2019	Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors.	Glycine	27-34	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	66-72
31444392-3	2019	Here, we examined the surface delivery and functional properties of NMDARs containing mutations in the glycine-binding sites in GluN1 and GluN3A subunits expressed in mammalian cell lines and primary rat hippocampal neurons.	Glycine	103-110	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	138-144
31444392-5	2019	In addition, we found that a potentially clinically relevant mutation in the glycine-binding site of the human GluN3A subunit significantly reduces surface delivery of NMDARs.	Glycine	77-84	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	111-117
20301531-9	1993	DIAGNOSIS/TESTING: Glycine encephalopathy is suspected in individuals with elevated glycine concentration in blood and CSF.	Glycine	19-26	colony stimulating factor 2	Homo sapiens	119-122
20301531-10	1993	An increase in CSF glycine concentration together with an increased CSF-to-plasma glycine ratio suggests the diagnosis.	Glycine	19-26	colony stimulating factor 2	Homo sapiens	15-18
20301531-10	1993	An increase in CSF glycine concentration together with an increased CSF-to-plasma glycine ratio suggests the diagnosis.	Glycine	82-89	colony stimulating factor 2	Homo sapiens	68-71
32254804-4	2019	The gold nanostars were further designed to be multifunctional nanoagents by labeling Raman molecules and then conjugating arginine-glycine-aspartic acid (RGD), which can serve as cancer cell-targeted SERS-imaging tags and photothermal nanoagents in both the NIR-I and NIR-II windows.	Glycine	132-139	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	201-205
30483907-7	2019	Western blot analysis showed that 100-200% glycine enhanced the protein levels of occludin, claudin-1, and zonula occludens (ZO)-1 without affecting those of claudin-3, ZO-2, and ZO-3.	Glycine	43-50	tight junction protein 3	Homo sapiens	179-183
30483907-8	2019	Further studies showed that protein abundances of glucose-regulated protein 78 (BiP/GRP78) and p-IRE1alpha, instead of ATF6alpha, were reduced by glycine.	Glycine	146-153	activating transcription factor 6	Homo sapiens	119-128
30702579-14	2019	INTERVENTIONS AND OUTCOMES: With regard to the sequencing of this patient, a heterozygous point mutation of G403C in PARK2 was detected, which was inherited from his unaffected mother, leading to an amino acid alternation of glycine to arginine.	Glycine	225-232	parkin RBR E3 ubiquitin protein ligase	Homo sapiens	117-122
30545625-5	2019	Here we found that a triple helix fragment of hCOL3A1, Gly489-Gly510, contained multiple charged residues, as well as representative Glu-Lys-Gly and Glu-Arg-Gly charged triplets.	Glycine	55-58	collagen type III alpha 1 chain	Homo sapiens	46-53
30545625-5	2019	Here we found that a triple helix fragment of hCOL3A1, Gly489-Gly510, contained multiple charged residues, as well as representative Glu-Lys-Gly and Glu-Arg-Gly charged triplets.	Glycine	62-65	collagen type III alpha 1 chain	Homo sapiens	46-53
29797328-7	2019	Knockdown of peptide transporter 1 (PepT1) resulted in less Gly-Sar uptake in OECs, whereas overexpression of PepT1 in OECs resulted in higher Gly-Sar uptake (P &lt; 0.05).	Glycine	60-63	solute carrier family 15 member 1	Bos taurus	13-34
29797328-7	2019	Knockdown of peptide transporter 1 (PepT1) resulted in less Gly-Sar uptake in OECs, whereas overexpression of PepT1 in OECs resulted in higher Gly-Sar uptake (P &lt; 0.05).	Glycine	60-63	solute carrier family 15 member 1	Bos taurus	36-41
29797328-7	2019	Knockdown of peptide transporter 1 (PepT1) resulted in less Gly-Sar uptake in OECs, whereas overexpression of PepT1 in OECs resulted in higher Gly-Sar uptake (P &lt; 0.05).	Glycine	143-146	solute carrier family 15 member 1	Bos taurus	110-115
30352320-5	2019	We found that ITGA5 is highly expressed in strongly migratory and invasive TNBC cells as well as their lung metastatic foci, which rationalizes active-targeted drug delivery to TNBC cells via ITGA5 ligands such as a commercialized ligand-RGD motif (Arg-Gly-Asp).	Glycine	253-256	integrin alpha 5 (fibronectin receptor alpha)	Mus musculus	14-19
30352320-5	2019	We found that ITGA5 is highly expressed in strongly migratory and invasive TNBC cells as well as their lung metastatic foci, which rationalizes active-targeted drug delivery to TNBC cells via ITGA5 ligands such as a commercialized ligand-RGD motif (Arg-Gly-Asp).	Glycine	253-256	integrin alpha 5 (fibronectin receptor alpha)	Mus musculus	192-197
30442778-4	2018	Like cells missing mitochondrial components of one-carbon metabolism, those null for SFXN1 are defective in glycine and purine synthesis.	Glycine	108-115	sideroflexin 1	Homo sapiens	85-90
30442778-5	2018	Cells lacking SFXN1 and one of its four homologs, SFXN3, have more severe defects, including being auxotrophic for glycine.	Glycine	115-122	sideroflexin 1	Homo sapiens	14-19
30442778-5	2018	Cells lacking SFXN1 and one of its four homologs, SFXN3, have more severe defects, including being auxotrophic for glycine.	Glycine	115-122	sideroflexin 3	Homo sapiens	50-55
29753073-0	2018	Glycine Transporter-1 and glycine receptor mediate the antioxidant effect of glycine in diabetic rat islets and INS-1 cells.	Glycine	26-33	insulin 1	Rattus norvegicus	112-117
29753073-5	2018	In INS-1 cells, glycine reduced the intracellular reactive oxygen species (ROS) concentration and inhibited apoptosis induced by high glucose or H2O2.	Glycine	16-23	insulin 1	Rattus norvegicus	3-8
29608917-8	2018	Chronic hyper-reflexia induced by GlyT2-ASO treatment was effectively blocked by intrathecal glycine.	Glycine	93-100	solute carrier family 6 member 5	Rattus norvegicus	34-39
29608917-10	2018	These data demonstrate that spinal GlyT2 downregulation provides only a time-limited therapeutic benefit and that subsequent loss of glycine vesicular synthesis resulting from chronic GlyT2 downregulation near completely eliminates the tonic glycine-ergic activity and is functionally expressed as profound spinal hyper-reflexia.	Glycine	133-140	solute carrier family 6 member 5	Rattus norvegicus	184-189
29608917-10	2018	These data demonstrate that spinal GlyT2 downregulation provides only a time-limited therapeutic benefit and that subsequent loss of glycine vesicular synthesis resulting from chronic GlyT2 downregulation near completely eliminates the tonic glycine-ergic activity and is functionally expressed as profound spinal hyper-reflexia.	Glycine	242-249	solute carrier family 6 member 5	Rattus norvegicus	184-189
29775303-3	2018	Analyzing the results of a previous virtual screening against murine double minute 2 protein (MDM2), we envisaged that Arg-Gly-Asp (RGD)-mimetic molecules could be inhibitors of MDM2/4.	Glycine	123-126	transformed mouse 3T3 cell double minute 2	Mus musculus	69-92
29775303-3	2018	Analyzing the results of a previous virtual screening against murine double minute 2 protein (MDM2), we envisaged that Arg-Gly-Asp (RGD)-mimetic molecules could be inhibitors of MDM2/4.	Glycine	123-126	transformed mouse 3T3 cell double minute 2	Mus musculus	94-98
29775303-3	2018	Analyzing the results of a previous virtual screening against murine double minute 2 protein (MDM2), we envisaged that Arg-Gly-Asp (RGD)-mimetic molecules could be inhibitors of MDM2/4.	Glycine	123-126	transformed mouse 3T3 cell double minute 2	Mus musculus	178-182
29460053-4	2018	For this, we investigated the expression of glycine receptor subunit alpha 3 (GlyRalpha3) and gephyrin in neurons in Vmes and the trigeminal motor nucleus (Vmo), and the Gly+ boutons that contact them by light- and electron-microscopic immunocytochemistry and quantitative ultrastructural analysis.	Glycine	78-81	glycine receptor, alpha 3	Rattus norvegicus	44-76
29626220-9	2018	Mendelian randomisation demonstrated a similar relationship for type 2 diabetes risk per 1 SD genetically increased glycine (OR 0.89 [95% CI 0.8, 0.99]) and phenylalanine (OR 1.6 [95% CI 1.08, 2.4]).	Glycine	116-123	olfactory receptor family 10 subfamily K member 1	Homo sapiens	172-178
4957443-4	1966	The results indicate that C-2 and C-8 of the purine ring are derived most efficiently from serine and glycine and not from formate.	Glycine	102-109	C8	Mycobacterium tuberculosis H37Rv	26-37
13942967-0	1962	Influence of testosterone on glycine incorporation into mouse kidney beta-glucuronidase.	Glycine	29-36	glucuronidase, beta	Mus musculus	69-87
34321660-4	2021	Here we describe the cryo-electron microscope structures of human GluN1-GluN2A and GluN1-GluN2B NMDA receptors in complex with S-ketamine, glycine and glutamate.	Glycine	139-146	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	89-95
33999213-9	2021	We also found that the two major methylation sites known to regulate TOP3B activity are located in the most conserved region of the C-terminal arginine-glycine-glycine (RGG) box, suggesting that a similar regulatory mechanism may operate throughout animals.	Glycine	152-159	DNA topoisomerase III beta	Homo sapiens	69-74
33999213-9	2021	We also found that the two major methylation sites known to regulate TOP3B activity are located in the most conserved region of the C-terminal arginine-glycine-glycine (RGG) box, suggesting that a similar regulatory mechanism may operate throughout animals.	Glycine	160-167	DNA topoisomerase III beta	Homo sapiens	69-74
34342168-2	2021	The glycine cleavage system and its rate-limiting enzyme, glycine decarboxylase (GLDC), is a major determinant of plasma glycine levels.	Glycine	4-11	glycine decarboxylase	Homo sapiens	58-79
33950796-2	2021	Inhibition of metabolic enzymes such as cholinesterases (ChEs; acetylcholinesterase, AChE and butyrylcholinesterase, BChE) and alpha-glucosidase (alpha-GLY) is one of the accepted approaches in the treatment of Alzheimer"s disease (AD) and diabetes mellitus (DM).	Glycine	152-155	butyrylcholinesterase	Homo sapiens	117-121
34342168-2	2021	The glycine cleavage system and its rate-limiting enzyme, glycine decarboxylase (GLDC), is a major determinant of plasma glycine levels.	Glycine	4-11	glycine decarboxylase	Homo sapiens	81-85
33950796-2	2021	Inhibition of metabolic enzymes such as cholinesterases (ChEs; acetylcholinesterase, AChE and butyrylcholinesterase, BChE) and alpha-glucosidase (alpha-GLY) is one of the accepted approaches in the treatment of Alzheimer"s disease (AD) and diabetes mellitus (DM).	Glycine	152-155	sucrase-isomaltase	Homo sapiens	127-144
29550603-2	2018	Serine racemase (SRR, encoded by Srr) converts L-serine to D-serine, an endogenous co-agonist at the glycine site of the NMDAR.	Glycine	101-108	serine racemase	Mus musculus	0-15
34342168-2	2021	The glycine cleavage system and its rate-limiting enzyme, glycine decarboxylase (GLDC), is a major determinant of plasma glycine levels.	Glycine	121-128	glycine decarboxylase	Homo sapiens	58-79
29550603-2	2018	Serine racemase (SRR, encoded by Srr) converts L-serine to D-serine, an endogenous co-agonist at the glycine site of the NMDAR.	Glycine	101-108	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	121-126
34342168-2	2021	The glycine cleavage system and its rate-limiting enzyme, glycine decarboxylase (GLDC), is a major determinant of plasma glycine levels.	Glycine	121-128	glycine decarboxylase	Homo sapiens	81-85
34342168-3	2021	The goals of this study were to determine if the increased expression of GLDC contributes to the reduced plasma glycine levels seen in disease states, to characterize the hormonal regulation of GLDC gene expression, and to determine if altered GLDC expression has physiological effects that might affect the development of diabetes.	Glycine	112-119	glycine decarboxylase	Homo sapiens	73-77
34275129-4	2021	Among dental NCPs, dentine sialophosphoprotein (DSPP) is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family, whose members share common biochemical characteristics such as an Arg-Gly-Asp (RGD) motif.	Glycine	213-216	dentin sialophosphoprotein	Homo sapiens	48-52
29872376-2	2018	D-serine, an endogenous co-agonist at the glycine-binding site of the N-methyl-D-aspartate-type glutamate receptor (NMDAR), has been shown to be involved in extinction of fear memory.	Glycine	42-49	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	70-114
29872376-2	2018	D-serine, an endogenous co-agonist at the glycine-binding site of the N-methyl-D-aspartate-type glutamate receptor (NMDAR), has been shown to be involved in extinction of fear memory.	Glycine	42-49	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	116-121
29351412-4	2018	In this report, we present experimental evidence showing that ECM stimulates the synthesis of CTGF in response to lysophosphatidic acid (LPA).The integrin/focal adhesion kinase (FAK) signaling pathway mediates this effect, since CTGF expression is abolished by the use of the Arg-Gly-Asp-Ser peptide and also by an inhibitor of FAK autophosphorylation at tyrosine 397.	Glycine	280-283	PTK2 protein tyrosine kinase 2	Mus musculus	146-176
29351412-4	2018	In this report, we present experimental evidence showing that ECM stimulates the synthesis of CTGF in response to lysophosphatidic acid (LPA).The integrin/focal adhesion kinase (FAK) signaling pathway mediates this effect, since CTGF expression is abolished by the use of the Arg-Gly-Asp-Ser peptide and also by an inhibitor of FAK autophosphorylation at tyrosine 397.	Glycine	280-283	PTK2 protein tyrosine kinase 2	Mus musculus	178-181
33854367-12	2021	GlyT2-tdTomato fluorescence was colocalized extensively with immunoreactivity of glycine, GlyT2 and Pax2 in somata, confirming the selective expression of the transgene in glycinergic neurons.	Glycine	81-88	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	0-5
33796945-1	2021	Gephyrin is a multifunctional scaffolding protein anchoring glycine- and subtypes of GABA type A- receptors at inhibitory postsynaptic membrane specializations by binding to the microtubule (MT) and/or the actin cytoskeleton.	Glycine	60-67	gephyrin	Homo sapiens	0-8
34244482-8	2021	Finally, we find that GLDC K514 acetylation inhibits glycine catabolism, pyrimidines synthesis and glioma tumorigenesis.	Glycine	53-60	glycine decarboxylase	Homo sapiens	22-26
33867731-0	2021	Evaluation of LKB1 and Serine-Glycine Metabolism Pathway Genes (SHMT1 and GLDC) Expression in AML.	Glycine	30-37	serine hydroxymethyltransferase 1	Homo sapiens	64-69
34244482-9	2021	Our finding reveals critical roles of post-translational modifications of GLDC in regulation of its enzymatic activity, glycine metabolism and tumorigenesis, and provides potential targets for therapeutics of cancers such as glioma.	Glycine	120-127	glycine decarboxylase	Homo sapiens	74-78
33738852-6	2021	Notably, results of the SPiDER-beta-Gal analysis suggested that glycine alleviated NaF-induced cellular senescence and downregulated P53, P21, HMGA2, and P16INK4a gene expression in the porcine testicular Sertoli cell line.	Glycine	64-71	high mobility group AT-hook 2	Homo sapiens	143-148
29611532-8	2018	Homology modelling and molecular docking analysis of ST14 with wild-type TMEFF1 protein was performed which revealed that glycine at position 439 is crucial for maintaining normal structural confirmation and interaction with the EGF domain of TMEFF1 protein.	Glycine	122-129	ST14 transmembrane serine protease matriptase	Homo sapiens	53-57
34212862-3	2021	We have identified two toddlers with different heterozygous missense mutations of the same, and highly conserved, glycine residue located in the ligand-binding-domain of GRIN2B: G689C and G689S.	Glycine	114-121	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	170-176
29559876-6	2018	Results: Tissue glycine levels are lower than the glutathione synthase Michaelis constant (Km) for glycine.	Glycine	99-106	glutathione synthetase	Homo sapiens	50-70
29288497-3	2018	Most ARS genes in these cellular compartments are distinct, but two genes are common, encoding aminoacyl-tRNA synthetases of glycine (GARS) and lysine (KARS) in both mitochondria and the cytosol.	Glycine	125-132	glycyl-tRNA synthetase 1	Homo sapiens	134-138
33850892-12	2021	In addition, the part of the residues on the TCR alpha or beta single chain that produced bond types of interaction with the polypeptide after being replaced by Ala or Gly, the intermolecular binding free energy of the complex was increased, regardless of whether HB was formed.	Glycine	168-171	T cell receptor alpha joining 60 (pseudogene)	Homo sapiens	45-54
33259793-3	2021	These events depend on the CAP-Gly motif found in dTBCE and are regulated by Ran and lamin proteins.	Glycine	31-34	Tubulin-specific chaperone E	Drosophila melanogaster	50-55
33608926-6	2021	Through a synergistic strategy of utilizing TB medium supplemented with 120 mM glycine and 10 mM calcium, the lag phase of protein secretion was reduced to 3 h from 12 h, meanwhile calcium remedied glycine-related cell growth impairment, leading to further enhancement of overall enzyme productivity, reaching the maximum of 4.55 U mL-1 .	Glycine	79-86	L1 cell adhesion molecule	Mus musculus	332-336
33453267-4	2021	Here, we show that charged arginine (R) residues in even short glycine (G) capped model peptides (GRRG and GRRRG) significantly affect the conformational propensities of each other when compared to the intrinsic propensities of a mostly unperturbed arginine in the tripeptide GRG.	Glycine	63-70	TLE family member 5, transcriptional modulator	Homo sapiens	276-279
33278020-8	2021	Dopamine D3 receptor (DRD3) Ser/Gly and ATP binding cassette subfamily B member 1 (ABCB1) rs10280101, rs12720067 and rs11983225 polymorphisms and cytochrome P450 3A (CYP3A) phenotype had an impact on plasma prolactin levels.	Glycine	32-35	dopamine receptor D3	Homo sapiens	22-26
33428336-1	2021	Recurrent glycine-to-arginine/valine alterations at codon 34 (G34R/V) within H3F3A gene characterize a subset of hemispheric high-grade gliomas (HGG) affecting children and young adults.	Glycine	10-17	H3.3 histone A	Homo sapiens	77-82
33428336-8	2021	Mutation at glycine 34 of the H3F3A gene was identified in 9 of the 24 tumors (37%) by direct sequencing, revealing 7 of 9 positive case by sequencing and 2 of 9 false negative cases by IHC.	Glycine	12-19	H3.3 histone A	Homo sapiens	30-35
33086983-5	2021	Introducing three glycine residues that disrupt a rigid IS6-AID helix markedly reduced basal open probability despite intact binding of CaVbeta to alpha1C I-II loop, and eliminated beta-adrenergic agonist stimulation of CaV1.2 current.	Glycine	18-25	B cell leukemia/lymphoma 2 related protein A1c	Mus musculus	147-154
33521601-5	2021	In this study, we solved the crystal structure of human serine hydroxymethyltransferase (hSHMT) in complex with an endogenous secondary bile acid glycine conjugate.	Glycine	146-153	serine hydroxymethyltransferase 1	Homo sapiens	89-94
33391421-1	2021	Introduction: Previous studies have shown that peptides containing the asparagine-glycine-arginine (NGR) sequence can specifically bind to CD13 (aminopeptidase N) receptor, a tumor neovascular biomarker that is over-expressed on the surface of angiogenic blood vessels and various tumor cells, and it plays an important role in angiogenesis and tumor progression.	Glycine	82-89	alanyl (membrane) aminopeptidase	Mus musculus	139-143
33523018-10	2021	Gly(2)-GLP-2 furthermore reduced the inflammation response as seen in lower microglia activation, and decreased NLRP3 and interleukin-1beta pro-inflammatory cytokine expression levels.	Glycine	0-3	NLR family, pyrin domain containing 3	Mus musculus	112-117
33086094-2	2020	The present study determined whether N,N-dimethylglycine (DMG), a nutrient supplement and a partial agonist for NMDAR glycine binding site, could counteract recognition memory deficits and hippocampal synaptic dysfunction after acute toluene exposure.	Glycine	49-56	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	112-117
33086094-7	2020	Furthermore, NMDAR glycine binding site antagonist, 7-chlorokynurenic acid, abolished the protective effects of DMG.	Glycine	19-26	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	13-18
33199076-3	2020	The freeze-dried heat-stable formulation ST16, containing excipient combinations of trehalose, glycine, thiourea and phosphate buffer shows the superior thermostability.	Glycine	95-102	interleukin 24	Homo sapiens	41-45
33310850-1	2020	Potassium-chloride cotransporters KCC1 to KCC4 mediate the coupled export of potassium and chloride across the plasma membrane and play important roles in cell volume regulation, auditory system function, and gamma-aminobutyric acid (GABA) and glycine-mediated inhibitory neurotransmission.	Glycine	244-251	solute carrier family 12 member 4	Homo sapiens	34-38
32436225-5	2020	KEY RESULTS: Our results support the existence of GlyR alpha2 subunits in accumbal neurons, since the glycine-evoked currents and glycinergic mIPSCs in the Glra2-/Y mice were drastically decreased.	Glycine	102-109	glycine receptor, alpha 2 subunit	Mus musculus	156-161
32608538-6	2020	Membrane cholesterol reduction significantly inhibits cannabinoid potentiation of glycine-activated currents in cultured spinal neurons and in HEK 293T cells expressing alpha1/alpha3 GlyRs.	Glycine	82-89	glycine receptor alpha 1	Homo sapiens	169-188
32685391-8	2020	CONCLUSION: The novel mutation in the MITF gene, which altered the protein in amino acids 213 from the glutamic acid to glycine, is the genetic pathological cause for WS features in the patient.	Glycine	120-127	melanocyte inducing transcription factor	Homo sapiens	38-42
32519543-5	2020	The optimized protocol used to remove Fmoc from Gly-residue was proved by the synthesis of Leu-enkephalin.	Glycine	48-51	prodynorphin	Homo sapiens	91-105
32423801-8	2020	Furthermore, expressions of vascular endothelial growth factor (VEGF) (an angiogenic factor) and nitric oxide synthase (NOS) (an enzyme for nitric oxide synthesis) were associated with the dose-dependent effects of glycine.	Glycine	215-222	vascular endothelial growth factor Aa	Danio rerio	28-62
32423801-8	2020	Furthermore, expressions of vascular endothelial growth factor (VEGF) (an angiogenic factor) and nitric oxide synthase (NOS) (an enzyme for nitric oxide synthesis) were associated with the dose-dependent effects of glycine.	Glycine	215-222	vascular endothelial growth factor Aa	Danio rerio	64-68
32423801-9	2020	Our results suggest that glycine exerts dose-dependent biphasic effects on vascular development, which rely on GlyTs and GlyRs, and correlate with the expression of VEGF and NOS genes.	Glycine	25-32	vascular endothelial growth factor Aa	Danio rerio	165-169
32555167-9	2020	The present data support a facilitating role of glycine and cAMP on network oscillations and synaptic efficacy at the CA3-CA1 circuit in rats, whereas raising endogenous D-serine levels had no such beneficial effects.	Glycine	48-55	carbonic anhydrase 1	Rattus norvegicus	122-125
32421439-2	2020	A naturally occurring single nucleotide polymorphism in the key extracellular antioxidant enzyme, extracellular superoxide dismutase (EC-SOD), results in an arginine to glycine substitution (R213G) which promotes resolution of inflammation and protection against bleomycin-induced ALI.	Glycine	169-176	superoxide dismutase 3, extracellular	Mus musculus	98-132
32421439-2	2020	A naturally occurring single nucleotide polymorphism in the key extracellular antioxidant enzyme, extracellular superoxide dismutase (EC-SOD), results in an arginine to glycine substitution (R213G) which promotes resolution of inflammation and protection against bleomycin-induced ALI.	Glycine	169-176	superoxide dismutase 3, extracellular	Mus musculus	134-140
34163069-2	2021	In human haematological malignancies, recurrent chromosomal translocation of nucleoporin (NUP98 or NUP214) generates an aberrant chimera that invariably retains the nucleoporin IDR-tandemly dispersed repeats of phenylalanine and glycine residues1,2.	Glycine	229-236	nucleoporin 98 and 96 precursor	Homo sapiens	90-95
31962186-0	2020	Glycine transporter type 1 (GlyT1) inhibition improves conspecific-provoked immobility in Balb/c mice: Analysis of corticosterone response and glucocorticoid gene expression in cortex and hippocampus.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	28-33
34163069-6	2021	An artificial HOX chimera, created by replacing the phenylalanine and glycine repeats of NUP98 with an unrelated LLPS-forming IDR of the FUS protein3,4, had similar enhancing effects on the genome-wide binding and target gene activation of the chimera.	Glycine	70-77	nucleoporin 98 and 96 precursor	Homo sapiens	89-94
32234784-4	2020	Our biophysical investigations show that TNPO1 recognizes an arginine-glycine(-glycine) (RG/RGG)-rich region, whereas TNPO3 recognizes a region rich in arginine-serine-tyrosine (RSY) residues.	Glycine	70-77	transportin 1	Homo sapiens	41-46
34083252-7	2021	Our data also indicate that MACs release glycine at conventional chemical synapses, and viral retrograde transsynaptic tracing from the dorsal lateral geniculate nucleus (dLGN) showed selective connections between MACs and a subpopulation of RGC types.	Glycine	41-48	myristoylated alanine rich protein kinase C substrate	Homo sapiens	28-32
32328471-0	2020	The First COL4A5 Exon 41A Glycine Substitution in a Family With Alport Syndrome.	Glycine	26-33	collagen type IV alpha 5 chain	Homo sapiens	10-16
32328471-12	2020	Conclusions: A glycine substitution in COL4A5 exon 41A was identified in a family with intrafamilial heterogeneity of the rate of progression to end-stage renal failure in male patients, which extends the phenotypic and mutational spectrum of X-linked Alport syndrome.	Glycine	15-22	collagen type IV alpha 5 chain	Homo sapiens	39-45
35619118-16	2022	Furthermore, phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme in serine-glycine pathway, was upregulated in human iCCA correlating with G9a expression.	Glycine	88-95	phosphoglycerate dehydrogenase	Homo sapiens	13-43
32228614-12	2020	Individual mutations of conserved ATP binding, RNA binding, helicase related or protein binding motifs within DDX5 show that the N terminal RNA binding motifs, the Walker B and the glycine doublet motifs are essential for this function.	Glycine	181-188	DEAD-box helicase 5	Homo sapiens	110-114
35619118-16	2022	Furthermore, phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme in serine-glycine pathway, was upregulated in human iCCA correlating with G9a expression.	Glycine	88-95	phosphoglycerate dehydrogenase	Homo sapiens	45-50
29110180-2	2018	AGT prevents oxalate formation by converting peroxisomal glyoxylate to glycine.	Glycine	71-78	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	0-3
35471651-0	2022	T- and pH-dependent OH radical reaction kinetics with glycine, alanine, serine, and threonine in the aqueous phase.	Glycine	54-61	phenylalanine hydroxylase	Homo sapiens	7-9
29306507-1	2018	The objective of this study is to determine the immunogenicity and safety of our novel anti-gastrin vaccine that is composed of the common amino-terminal portions of human carboxy-amidated gastrin-17 (G17) and glycine-extended gastrin-17 (gly-G17) as well as the common carboxy-terminal portion of the gastrin precursor progastrin (in a 50:50 mixture) all covalently linked to tetanus toxoid (TT) via peptide spacers.	Glycine	210-217	gastrin	Homo sapiens	92-99
29306507-1	2018	The objective of this study is to determine the immunogenicity and safety of our novel anti-gastrin vaccine that is composed of the common amino-terminal portions of human carboxy-amidated gastrin-17 (G17) and glycine-extended gastrin-17 (gly-G17) as well as the common carboxy-terminal portion of the gastrin precursor progastrin (in a 50:50 mixture) all covalently linked to tetanus toxoid (TT) via peptide spacers.	Glycine	210-213	gastrin	Homo sapiens	92-99
29886758-0	2018	Phage display selection of fully human antibody fragments to inhibit growth-promoting effects of glycine-extended gastrin 17 on human colorectal cancer cells.	Glycine	97-104	gastrin	Homo sapiens	114-121
32187235-7	2020	We identified a reproducible amino acid substitution from glutamic acid (E) to glycine (G) or glutamine (Q) in residue 145 of the VP1 protein (VP1-145) after adaptation to RD-A cells, which was associated with attenuation in human scavenger receptor B2 transgenic (hSCARB2 tg) mice.	Glycine	79-86	scavenger receptor class B member 2	Homo sapiens	265-272
35507758-5	2022	To obtain novel inhibitors of the enzyme, the amino group of this substrate was replaced with functional groups that occur in known AOC3 inhibitors, such as hydrazide or glycine amide moieties.	Glycine	170-177	amine oxidase copper containing 3	Homo sapiens	132-136
31976148-3	2020	We report a baby with typical clinical features and supportive laboratory findings, who had a homozygous missense variation in exon 19 of STXBP2 that results in an amino acid substitution of aspartic acid for glycine.	Glycine	209-216	syntaxin binding protein 2	Homo sapiens	138-144
32110933-0	2020	Glycine Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Regulating NLRP3 Inflammasome and NRF2 Signaling.	Glycine	0-7	NLR family, pyrin domain containing 3	Mus musculus	78-83
32110933-6	2020	Further study showed that glycine-reduced LPS challenge resulted in the upregulation of nuclear factor kappaB (NF-kappaB), nucleotide binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome.	Glycine	26-33	NLR family, pyrin domain containing 3	Mus musculus	180-185
32110933-8	2020	Our findings indicated that glycine pretreatment prevented LPS-induced lung injury by regulating both NLRP3 inflammasome and NRF2 signaling.	Glycine	28-35	NLR family, pyrin domain containing 3	Mus musculus	102-107
29886758-1	2018	Glycine-extended gastrin 17 (G17-Gly), a dominant processing intermediate of gastrin gene, has been implicated in the development or maintenance of colorectal cancers (CRCs).	Glycine	0-7	gastrin	Homo sapiens	17-24
29886758-1	2018	Glycine-extended gastrin 17 (G17-Gly), a dominant processing intermediate of gastrin gene, has been implicated in the development or maintenance of colorectal cancers (CRCs).	Glycine	0-7	gastrin	Homo sapiens	77-84
28930530-3	2018	The 24SMBc blpU-like cassette  is 8,023 bp in length, organized in 11 orfs,of which orf8 encodes for the pore-forming peptide bacteriocin, belonging to class IIc, with a double-glycine leader peptide.	Glycine	177-184	SSAL8618_RS09415	Streptococcus salivarius	126-137
35460232-7	2022	The strongest associations for serine-glycine ratio were with single nucleotide polymorphisms (SNPs) in ALDH1L1 and glycine decarboxylase (GLDC) and for glycine with GLDC (P < 3.5 x 10-8, effect sizes: 0.03-0.07).	Glycine	153-160	glycine decarboxylase	Homo sapiens	166-170
32046769-10	2020	In a LAT2 knock-out mouse model, CSF Gln was unchanged, whereas other amino acids normally 2-20-fold lower than in plasma, were increased, in particular the LAT2 uptake substrates leucine (Leu), valine (Val) and tryptophan (Trp) and some other amino acids such as glutamate (Glu), glycine (Gly) and proline (Pro).	Glycine	281-288	linker for activation of T cells family, member 2	Mus musculus	157-161
32046769-10	2020	In a LAT2 knock-out mouse model, CSF Gln was unchanged, whereas other amino acids normally 2-20-fold lower than in plasma, were increased, in particular the LAT2 uptake substrates leucine (Leu), valine (Val) and tryptophan (Trp) and some other amino acids such as glutamate (Glu), glycine (Gly) and proline (Pro).	Glycine	290-293	linker for activation of T cells family, member 2	Mus musculus	157-161
35291874-2	2022	Apart from GAA synthesized internally from glycine and arginine, a total daily exposure to GAA also involves exogenous dietary sources.	Glycine	43-50	alpha glucosidase	Homo sapiens	11-14
31985312-0	2021	First Detection of Hb Cenxi [beta46(CD5)Gly Arg (GGG>CGG), HBB: c.139G>C] by Capillary Electrophoresis.	Glycine	40-43	CD5 molecule	Homo sapiens	36-39
29483823-6	2018	The serum metabonomics study showed that the LDLR-/- ,PSGL-1-/- mice had higher levels of HDL, valine, acetate, pyruvate, choline, PC, GPC and glycine, and lower levels of LDL+VLDL and lactate at the early stage of atherosclerosis, while lactate, citrate and glutamine showed statistical significance at the late stage of atherosclerosis.	Glycine	143-150	selectin, platelet (p-selectin) ligand	Mus musculus	54-60
28050793-7	2018	GLY also decreased the phosphorylation of p38, ERK1/2, and JNK 30 min after its administration in both brain structures.	Glycine	0-3	mitogen-activated protein kinase 8	Rattus norvegicus	59-62
31835170-1	2019	GABAA and glycine receptors are thought to compete for gephyrin-binding sites at mixed inhibitory synapses.	Glycine	10-17	gephyrin	Homo sapiens	55-63
35371538-2	2022	At 20 K for the O-H O hydrogen bond between the glycinium cation and the zwitterionic, unprotonated glycine mol-ecule that is associated with the ferroelectric behaviour of HTGS, O-H = 1.070 (3), H O = 1.408 (3) (delta = 0.338 (4)), O O = 2.4777 (15) A and O-H O = 179.0 (4) , which is in good agreement with previous studies.	Glycine	100-107	HTGS	Homo sapiens	173-177
34624079-6	2022	Mechanistically, SHMT2 inhibition led to a significant reduction of intracellular glycine and formate levels, which inhibited the mTOR pathway and thereby triggered autophagic degradation of the oncogenic transcription factor TCF3.	Glycine	82-89	transcription factor 3	Homo sapiens	226-230
31805132-7	2019	RESULTS: Treatment with a PPARalpha agonist was associated with increased plasma concentrations of most biomarkers, with the most pronounced differences observed for betaine, dimethylglycine, glycine, nicotinamide, methylnicotinamide, pyridoxal and methylmalonic acid.	Glycine	183-190	peroxisome proliferator activated receptor alpha	Rattus norvegicus	26-35
35187416-6	2022	Cys-528 in the elephant shark PR corresponds to Gly-722 in the human PR, which is essential for RU486 inhibition of the human PR.	Glycine	48-51	progesterone receptor	Callorhinchus milii	30-32
31591185-4	2019	The interaction between RhoB and Arf6 is mediated by the GCI (glycine, cysteine, and isoleucine) residues (188-190) of RhoB.	Glycine	62-69	ADP ribosylation factor 6	Homo sapiens	33-37
30737140-11	2019	Decreased ALAS2 activity results either directly from loss-of-function ALAS2 mutations as seen in X-linked sideroblastic anemia (XLSA) or from defect in the availability of one of its two mitochondrial substrates: glycine in SLC25A38 mutations and succinyl CoA in GLRX5 mutations.	Glycine	214-221	glutaredoxin 5	Homo sapiens	264-269
31612303-0	2019	MicroRNA-26b/PTEN Signaling Pathway Mediates Glycine-Induced Neuroprotection in SAH Injury.	Glycine	45-52	microRNA 26b	Homo sapiens	0-12
29079572-3	2017	An absolutely conserved Gly in the middle of the alpha1-helix of betaI helps maintain the resting betaI conformation, whereas the homologous position in the alphaI alpha1-helix contains a conserved Phe.	Glycine	24-27	adrenoceptor alpha 1D	Homo sapiens	49-55
29285162-4	2017	An MTT assay was used to detect the effects of bFGF and FN on osteoblast adhesion or proliferation on cell/scaffold constructs through blocking the extracellular matrix FN-integrin pathway by the Gly-Arg-Gly-Asp-Ser (GRGDS) peptide.	Glycine	196-199	fibronectin 1	Rattus norvegicus	56-58
29285162-4	2017	An MTT assay was used to detect the effects of bFGF and FN on osteoblast adhesion or proliferation on cell/scaffold constructs through blocking the extracellular matrix FN-integrin pathway by the Gly-Arg-Gly-Asp-Ser (GRGDS) peptide.	Glycine	196-199	fibronectin 1	Rattus norvegicus	169-171
30647695-9	2017	On the other hand, Se and GLY reduced hydrogen peroxide-mediated production of TNF-alpha, IL-1, IL-6 and expression of iNOS and NF-kappaB.	Glycine	26-29	interleukin 1 alpha	Homo sapiens	90-94
30647695-9	2017	On the other hand, Se and GLY reduced hydrogen peroxide-mediated production of TNF-alpha, IL-1, IL-6 and expression of iNOS and NF-kappaB.	Glycine	26-29	inositol-3-phosphate synthase 1	Homo sapiens	119-123
31612303-0	2019	MicroRNA-26b/PTEN Signaling Pathway Mediates Glycine-Induced Neuroprotection in SAH Injury.	Glycine	45-52	phosphatase and tensin homolog	Homo sapiens	13-17
31612303-3	2019	We have previously demonstrated that glycine, a non-essential amino acid is involved in neuroprotection following intracerebral hemorrhage via the Phosphatase and tensin homolog (PTEN)/protein kinase B (AKT) signaling pathway.	Glycine	37-44	phosphatase and tensin homolog	Homo sapiens	147-177
31612303-3	2019	We have previously demonstrated that glycine, a non-essential amino acid is involved in neuroprotection following intracerebral hemorrhage via the Phosphatase and tensin homolog (PTEN)/protein kinase B (AKT) signaling pathway.	Glycine	37-44	phosphatase and tensin homolog	Homo sapiens	179-183
2792654-0	1989	Glycine-extended processing intermediates of gastrin and cholecystokinin in human plasma.	Glycine	0-7	gastrin	Homo sapiens	45-52
31612303-3	2019	We have previously demonstrated that glycine, a non-essential amino acid is involved in neuroprotection following intracerebral hemorrhage via the Phosphatase and tensin homolog (PTEN)/protein kinase B (AKT) signaling pathway.	Glycine	37-44	protein tyrosine kinase 2 beta	Homo sapiens	185-201
31612303-9	2019	Glycine was shown to upregulate miRNA-26b, which led to PTEN downregulation followed by AKT activation, resulting in inhibition of neuronal death.	Glycine	0-7	phosphatase and tensin homolog	Homo sapiens	56-60
31612303-10	2019	Inhibition of miRNA-26b, PTEN or AKT activation suppressed the neuroprotective effects of glycine.	Glycine	90-97	phosphatase and tensin homolog	Homo sapiens	25-29
31612303-12	2019	Taken together, we conclude that glycine has neuroprotective effects in SAH and is mediated by the miRNA-26b/PTEN/AKT signaling pathway, which may be a therapeutic target for treatment of SAH injury.	Glycine	33-40	phosphatase and tensin homolog	Homo sapiens	109-113
31653237-3	2019	Clinical studies suggested that NMDAR modulators (glycine, D-serine, D-cycloserine and glycine transporter inhibitors) may be beneficial in treating schizophrenia patients.	Glycine	50-57	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	32-37
31653237-3	2019	Clinical studies suggested that NMDAR modulators (glycine, D-serine, D-cycloserine and glycine transporter inhibitors) may be beneficial in treating schizophrenia patients.	Glycine	87-94	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	32-37
31601771-0	2019	Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula.	Glycine	23-30	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	37-42
31601771-1	2019	The unconventional N-methyl-d-aspartate (NMDA) receptor subunits GluN3A and GluN3B can, when associated with the other glycine-binding subunit GluN1, generate excitatory conductances purely activated by glycine.	Glycine	119-126	glutamate receptor, ionotropic, NMDA3B	Mus musculus	76-82
31601771-1	2019	The unconventional N-methyl-d-aspartate (NMDA) receptor subunits GluN3A and GluN3B can, when associated with the other glycine-binding subunit GluN1, generate excitatory conductances purely activated by glycine.	Glycine	119-126	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	143-148
31601771-1	2019	The unconventional N-methyl-d-aspartate (NMDA) receptor subunits GluN3A and GluN3B can, when associated with the other glycine-binding subunit GluN1, generate excitatory conductances purely activated by glycine.	Glycine	203-210	glutamate receptor, ionotropic, NMDA3B	Mus musculus	76-82
31601771-1	2019	The unconventional N-methyl-d-aspartate (NMDA) receptor subunits GluN3A and GluN3B can, when associated with the other glycine-binding subunit GluN1, generate excitatory conductances purely activated by glycine.	Glycine	203-210	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	143-148
31230195-11	2019	Whereas COL4A1-related disorders are typically caused by glycine substitutions in the collagenous domain (84.4% of variants), only one variant in our cohort is a glycine substitution within the collagenous domain (1/10).	Glycine	57-64	collagen type IV alpha 1 chain	Homo sapiens	8-14
31230195-12	2019	We identified heterozygous COL4A1 mutations as a potential novel autosomal dominant cause of CAKUT that is allelic to the established COL4A1-related disorders and predominantly caused by non-glycine substitutions.	Glycine	191-198	collagen type IV alpha 1 chain	Homo sapiens	27-33
31351182-4	2019	The phylogenetic results show that CAOs can be classified based on two residues, X1 and X2, from the active site motif: T/S-X1-X2-N-Y-D. Residue X2 discriminates among the AOC1 (Tyr), AOC2 (Gly), and AOC3/AOC4 (Leu) proteins, while residue X1 further classifies the AOC3 (Leu) and AOC4 (Met) proteins that so far have been poorly identified and annotated.	Glycine	190-193	amine oxidase copper containing 2	Homo sapiens	184-188
31202607-3	2019	Importantly, GluN1/GluN3A and GluN1/GluN3B receptors form glycine-gated receptors.	Glycine	58-65	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	19-25
31337706-4	2019	MYC suppression attenuated [13C6]glucose, D3-serine, and [13C2]glycine incorporation into purines and reduced proliferation in PC9 but not in A549 cells.	Glycine	63-70	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	0-3
31393856-4	2019	This vulnerability was manifest both in vitro and in vivo, as dietary restriction of serine and glycine in mice was able to inhibit the growth of SF3B1MUT xenografts.	Glycine	96-103	splicing factor 3b, subunit 1	Mus musculus	146-154
31076642-5	2019	The expression of Gly-tRF was downregulated in C3-deficient or CR2-Crry-treated mice, but not in C5-deficient mice; Gly-tRF expression was restored by the C3 activation products C3a or Asp (C3a-des-Arg) via the regulation of CYP2E1.	Glycine	18-21	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	225-231
31076642-5	2019	The expression of Gly-tRF was downregulated in C3-deficient or CR2-Crry-treated mice, but not in C5-deficient mice; Gly-tRF expression was restored by the C3 activation products C3a or Asp (C3a-des-Arg) via the regulation of CYP2E1.	Glycine	116-119	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	225-231
31076642-6	2019	Transcriptome profiling of hepatic tissues showed that Gly-tRF inhibitors upregulate the expression of sirtuin1 (Sirt1) and subsequently affect downstream lipogenesis and beta-oxidation pathways.	Glycine	55-58	sirtuin 1	Mus musculus	103-111
31076642-6	2019	Transcriptome profiling of hepatic tissues showed that Gly-tRF inhibitors upregulate the expression of sirtuin1 (Sirt1) and subsequently affect downstream lipogenesis and beta-oxidation pathways.	Glycine	55-58	sirtuin 1	Mus musculus	113-118
30926317-9	2019	The site-directed mutagenesis of Thr163 and Val200 in human DHRS11 to the corresponding residues (Gly and Leu, respectively) in rabbit DHRS11 suggested that these residues are pertinent to the differences in properties of rabbit and human DHRS11s.	Glycine	98-101	dehydrogenase/reductase 11	Homo sapiens	60-66
30926317-9	2019	The site-directed mutagenesis of Thr163 and Val200 in human DHRS11 to the corresponding residues (Gly and Leu, respectively) in rabbit DHRS11 suggested that these residues are pertinent to the differences in properties of rabbit and human DHRS11s.	Glycine	98-101	LOW QUALITY PROTEIN: dehydrogenase/reductase SDR family member 11	Oryctolagus cuniculus	135-141
31021607-6	2019	ACE prefers to cleave substrates with Phe or Leu at the C-terminal P2" position and Gly in the P6 position.	Glycine	84-87	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	0-3
30759996-0	2019	BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.	Glycine	75-82	bolA family member 3	Homo sapiens	6-26
30858177-7	2019	Substitutions at Asp-109 and Gly-112 lock PCFT in an inward-open conformation, resulting in the loss of function.	Glycine	29-32	solute carrier family 46 member 1	Homo sapiens	42-46
30659259-5	2019	SLC7A2 was associated with the plasma levels of arginine and ornithine, and PKD1L2 with the level of glycine.	Glycine	101-108	polycystin 1 like 2 (gene/pseudogene)	Homo sapiens	76-82
31807622-6	2019	Despite being rich in cysteine, the caprine KAP15-1 protein possesses a high content of serine and moderate content of glycine and phenylalanine.	Glycine	119-126	keratin-associated protein 15-1	Capra hircus	44-51
30710045-10	2019	Moreover, we confirm that glycine-regulated AKT activation is mediated by the inhibition of PTEN in a PTEN depletion cell line, U251 cells.	Glycine	26-33	phosphatase and tensin homolog	Homo sapiens	92-96
30710045-10	2019	Moreover, we confirm that glycine-regulated AKT activation is mediated by the inhibition of PTEN in a PTEN depletion cell line, U251 cells.	Glycine	26-33	phosphatase and tensin homolog	Homo sapiens	102-106
30787298-1	2019	Serine hydroxymethyltransferase (SHMT) is an enzyme that catalyzes the reaction that converts serine to glycine.	Glycine	104-111	serine hydroxymethyltransferase 1	Homo sapiens	0-31
30787298-1	2019	Serine hydroxymethyltransferase (SHMT) is an enzyme that catalyzes the reaction that converts serine to glycine.	Glycine	104-111	serine hydroxymethyltransferase 1	Homo sapiens	33-37
30787298-7	2019	Here, we focus on the SHMT-catalyzed retro-aldol reaction rather than the canonical serine-glycine conversion and succeed in developing fluorescent and 19F NMR molecular probes.	Glycine	91-98	serine hydroxymethyltransferase 1	Homo sapiens	22-26
30391323-1	2019	D-Serine, an endogenous coagonist of N-methyl-d-aspartate receptors (NMDARs) at the glycine binding site, is synthesized by serine racemase (SR) through conversion of l-Serine.	Glycine	84-91	serine racemase	Mus musculus	124-139
30391323-1	2019	D-Serine, an endogenous coagonist of N-methyl-d-aspartate receptors (NMDARs) at the glycine binding site, is synthesized by serine racemase (SR) through conversion of l-Serine.	Glycine	84-91	serine racemase	Mus musculus	141-143
30522268-1	2019	Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate (THF) to glycine and 5,10-methylene THF.	Glycine	168-175	serine hydroxymethyltransferase 1	Homo sapiens	0-31
30522268-1	2019	Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate (THF) to glycine and 5,10-methylene THF.	Glycine	168-175	serine hydroxymethyltransferase 1	Homo sapiens	33-37
29675575-6	2019	Our in vivo results showed that GLY increased the activities of the antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), and glucose-6-phosphate dehydrogenase (G6PDH) in striatum.	Glycine	32-35	glutathione-disulfide reductase	Rattus norvegicus	146-167
29675575-6	2019	Our in vivo results showed that GLY increased the activities of the antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), and glucose-6-phosphate dehydrogenase (G6PDH) in striatum.	Glycine	32-35	glutathione-disulfide reductase	Rattus norvegicus	169-171
29675575-9	2019	Regarding the effects of BEZ, we found that GLY-induced increase of GPx, SOD, and GR activities was attenuated or prevented by this compound.	Glycine	44-47	glutathione-disulfide reductase	Rattus norvegicus	82-84
32124747-6	2019	The increased risk of influenza development is associated with the Asp/Gly genotype of TLR-4 (OR=4.22) and combination of mutant genotypes Leu/Phe and Phe/Phe of TLR-3 with Asp/Gly of TLR-4 and Arg/Gln of TLR-2 (OR=15.0); influenza-associated pneumonia - with genotype Phe/Phe of TLR-3 (OR=4.5).	Glycine	71-74	toll like receptor 4	Homo sapiens	87-92
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	22-29	glutamate receptor, ionotropic, NMDA3B	Mus musculus	11-17
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	22-29	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	64-77
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	22-29	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	79-84
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	22-29	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	120-125
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	180-187	glutamate receptor, ionotropic, NMDA3B	Mus musculus	11-17
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	180-187	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	64-77
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	180-187	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	79-84
30425244-1	2018	GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.	Glycine	180-187	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	120-125
30425244-7	2018	Finally, using CGP-78608 on P8-P12 mouse hippocampal slices, we demonstrate that excitatory glycine GluN1/GluN3A NMDARs are functionally expressed in native neurons, at least in the juvenile brain.	Glycine	92-99	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	100-105
30322002-0	2018	Effects of Glycine on Collagen, PDGF, and EGF Expression in Model of Oral Mucositis.	Glycine	11-18	epidermal growth factor	Homo sapiens	42-45
30322002-10	2018	The glycine group presented lower immunoexpression of the growth factors, EGF and PDGF.	Glycine	4-11	epidermal growth factor	Homo sapiens	74-77
30322002-11	2018	The group supplemented with glycine showed a marked healing process of the oral mucosite, demonstrated by the predominance of collagen type I and reduction of growth factors, EGF and PDGF.	Glycine	28-35	epidermal growth factor	Homo sapiens	175-178
29742476-6	2018	It is interestingly that various NOMs (i.e., humic acid (HA) and glycine (Gly)) exerted different effects on the adsorption behaviors, probably due to the different affinities for Pb2+, Cd2+ and Ni2+ and the redistribution of newly-formed metal-DOM complexes.	Glycine	65-72	CD2 molecule	Homo sapiens	186-189
29742476-6	2018	It is interestingly that various NOMs (i.e., humic acid (HA) and glycine (Gly)) exerted different effects on the adsorption behaviors, probably due to the different affinities for Pb2+, Cd2+ and Ni2+ and the redistribution of newly-formed metal-DOM complexes.	Glycine	74-77	CD2 molecule	Homo sapiens	186-189
29808289-2	2018	After its presynaptic release and binding to postsynaptic receptors at caudal glycinergic synapses, two high-affinity glycine transporters GlyT1 and GlyT2 remove glycine from the extracellular space.	Glycine	78-85	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	139-144
29808289-2	2018	After its presynaptic release and binding to postsynaptic receptors at caudal glycinergic synapses, two high-affinity glycine transporters GlyT1 and GlyT2 remove glycine from the extracellular space.	Glycine	78-85	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	149-154
29808289-3	2018	Glycinergic neurons express GlyT2, which is essential for the presynaptic replenishment of the transmitter, while glial-expressed GlyT1 was shown to control the extracellular glycine concentration.	Glycine	175-182	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	130-135
29808289-4	2018	Here we show that GlyT1 expressed by glycinergic amacrine cells of the retina does not only contribute to the control of the extracellular glycine concentration in the retina but is also essential for the maintenance of the glycinergic transmitter phenotype of this cell population.	Glycine	37-44	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	18-23
29808289-5	2018	Specifically, loss of GlyT1 from the glycinergic AII amacrine cells impairs AII-mediated glycinergic neurotransmission and alters regulation of the extracellular glycine concentration, without changes in the overall distribution and/or size of glycinergic synapses.	Glycine	37-44	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	22-27
30063827-2	2018	However, besides glycine, a plethora of other compounds are also generated when CH2O and HCN react in the presence of ammonia and water.	Glycine	17-24	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	89-92
30060651-4	2018	In an in vitro assay, ginger-degraded collagen hydrolysate enriched with X-Hyp-Gly-type tripeptides dose-dependently inhibited ACE and various synthetic X-Hyp-Gly-type tripeptides showed ACE-inhibitory activity.	Glycine	79-82	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	127-130
30060651-4	2018	In an in vitro assay, ginger-degraded collagen hydrolysate enriched with X-Hyp-Gly-type tripeptides dose-dependently inhibited ACE and various synthetic X-Hyp-Gly-type tripeptides showed ACE-inhibitory activity.	Glycine	79-82	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	187-190
30060651-6	2018	Surprisingly, substitution of Hyp with Pro dramatically decreased inhibitory activity of X-Hyp-Gly, indicating that Hyp is important for ACE inhibition.	Glycine	95-98	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	137-140
30140249-6	2018	The conserved glycine is located in the S4-S5 linker, a crucial domain controlling Kv1.1 channel gating.	Glycine	14-21	potassium voltage-gated channel subfamily A member 1	Homo sapiens	83-88
29769318-5	2018	Phe-371 at the PKG Ialpha glycine-rich loop is oriented parallel to the phenyl ring of N46, forming a strong pi-stacking interaction, whereas the analogous Phe-54 in PKA Calpha rotates 30  and forms a weaker interaction.	Glycine	26-33	protein kinase cGMP-dependent 1	Homo sapiens	15-18
29769318-7	2018	The analogous Gly-370 in PKG Ialpha, however, causes little steric hindrance with Phe-371.	Glycine	14-17	protein kinase cGMP-dependent 1	Homo sapiens	25-28
29684535-11	2018	In conclusion, there was a reduction in the hypotensive effects of IPP and LKP in SHRs when intestinal PepT1 was inhibited by Gly-Sar, but C10 may circumvent this by enhancing paracellular permeability.	Glycine	126-129	solute carrier family 15 member 1	Rattus norvegicus	103-108
30140759-7	2018	Moreover, the kidney relative weight, iron content in liver, spleen, kidney and femur, RBC (d 1) and HGB (d 21) in blood, and SI (d 1) in the Fe-Gly groups increased (P &lt; 0.05) compared with the FeSO4 H2O treatment.	Glycine	145-148	iodothyronine deiodinase 1	Sus scrofa	92-95
30140759-7	2018	Moreover, the kidney relative weight, iron content in liver, spleen, kidney and femur, RBC (d 1) and HGB (d 21) in blood, and SI (d 1) in the Fe-Gly groups increased (P &lt; 0.05) compared with the FeSO4 H2O treatment.	Glycine	145-148	iodothyronine deiodinase 1	Sus scrofa	130-133
29638041-5	2018	The quick technique of efficient molecular docking provided insight into the strong binding of L-rhamnose to the fat-digesting glycine residue of beta3 -adrenergic receptor (AR), indicating strong involvement of L-rhamnose in fat metabolism.	Glycine	127-134	adrenoceptor beta 3	Homo sapiens	146-172
29849110-3	2018	In this research we report a FRalpha binding peptide C7(Met-His-Thr-Ala-Pro-Gly-Trp-Gly-Tyr-Arg-Leu-Ser) discovered by phage display and this peptide showed specific binding to FRalpha expressing cells by cell ELISA and flow cytometry.	Glycine	76-79	FOS like 1, AP-1 transcription factor subunit	Homo sapiens	29-36
29849110-3	2018	In this research we report a FRalpha binding peptide C7(Met-His-Thr-Ala-Pro-Gly-Trp-Gly-Tyr-Arg-Leu-Ser) discovered by phage display and this peptide showed specific binding to FRalpha expressing cells by cell ELISA and flow cytometry.	Glycine	76-79	FOS like 1, AP-1 transcription factor subunit	Homo sapiens	177-184
29849110-3	2018	In this research we report a FRalpha binding peptide C7(Met-His-Thr-Ala-Pro-Gly-Trp-Gly-Tyr-Arg-Leu-Ser) discovered by phage display and this peptide showed specific binding to FRalpha expressing cells by cell ELISA and flow cytometry.	Glycine	84-87	FOS like 1, AP-1 transcription factor subunit	Homo sapiens	29-36
29849110-3	2018	In this research we report a FRalpha binding peptide C7(Met-His-Thr-Ala-Pro-Gly-Trp-Gly-Tyr-Arg-Leu-Ser) discovered by phage display and this peptide showed specific binding to FRalpha expressing cells by cell ELISA and flow cytometry.	Glycine	84-87	FOS like 1, AP-1 transcription factor subunit	Homo sapiens	177-184
29695955-3	2018	GLYX-13 is an NMDAR glycine-site functional partial agonist and cognitive enhancer that does not induce psychotomimetic side effects.	Glycine	20-27	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	14-19
29471495-4	2018	Protein arginine methyltransferase (PRMT) 1, PRMT3 and PRMT6 all methylate TOP3B in vitro at its C-terminal arginine (R) and glycine (G)-rich motif.	Glycine	125-132	DNA topoisomerase III beta	Homo sapiens	75-80
29576319-3	2018	The crystal structures of the CAP-Gly domain of Bik1 (Bik1CG) alone and in complex with an ETF peptide revealed unique, functionally relevant CAP-Gly elements, establishing Bik1CG as a specific C-terminal phenylalanine recognition domain.	Glycine	146-149	TEA domain transcription factor 2	Homo sapiens	91-94
29333938-8	2018	Insertion of two glycines in both the heavy and light chain elbow regions provided sufficient flexibility for the variable domains to extend further apart than the wild-type Fab, and allow the CDR3s to make additional interactions not seen in the wild-type Fab structure.	Glycine	17-25	FA complementation group B	Homo sapiens	174-177
29333938-8	2018	Insertion of two glycines in both the heavy and light chain elbow regions provided sufficient flexibility for the variable domains to extend further apart than the wild-type Fab, and allow the CDR3s to make additional interactions not seen in the wild-type Fab structure.	Glycine	17-25	FA complementation group B	Homo sapiens	257-260
28513838-2	2018	NPNT protein belongs to the epidermal growth factor (EGF)-like superfamily and exhibits several common structural determinants; including EGF-like repeat domains, MAM domain (Meprin, A5 Protein, and Receptor Protein-Tyrosine Phosphatase micro), RGD motif (Arg-Gly-Asp) and a coiled-coil domain.	Glycine	260-263	nephronectin	Homo sapiens	0-4
29339156-1	2018	Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of serine and glycine, which is crucial for one carbon metabolism.	Glycine	83-90	serine hydroxymethyltransferase 1	Homo sapiens	33-37
29019082-2	2018	TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such as L-glycine and L-glutamate or sweet molecules such as sucrose and fructose when dimerized with TAS1R member 1 (TAS1R1) or TAS1R member 2 (TAS1R2), respectively.	Glycine	87-96	taste receptor, type 1, member 3	Mus musculus	0-14
29019082-2	2018	TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such as L-glycine and L-glutamate or sweet molecules such as sucrose and fructose when dimerized with TAS1R member 1 (TAS1R1) or TAS1R member 2 (TAS1R2), respectively.	Glycine	87-96	taste receptor, type 1, member 3	Mus musculus	16-22
29019082-2	2018	TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such as L-glycine and L-glutamate or sweet molecules such as sucrose and fructose when dimerized with TAS1R member 1 (TAS1R1) or TAS1R member 2 (TAS1R2), respectively.	Glycine	87-96	taste receptor, type 1, member 2	Mus musculus	224-230
29346445-2	2018	The majority of disease-causing variants in COL3A1 are glycine substitutions and in-frame splice mutations in the triple helix domain that through a dominant negative effect are associated with the severe clinical spectrum potentially lethal of vEDS, characterized by fragility of soft connective tissues with arterial and organ ruptures.	Glycine	55-62	collagen type III alpha 1 chain	Homo sapiens	44-50
29427106-9	2018	The clusters surrounding residual neuronal cell bodies and dendrites are interpreted as a response to loss of gamma-aminobutyric acid (GABA)-A-receptors and lack of gephyrin, a protein that accomplishes the proper positioning of GABA-A- and glycine receptors.	Glycine	241-248	gephyrin	Homo sapiens	165-173
29413527-1	2018	The N-methyl-d-aspartate receptor (NMDAR) is unique in requiring two agonists to bind simultaneously to open its cation channel: the neurotransmitter, glutamate, and the coagonists, glycine, or d-serine.	Glycine	182-189	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	4-33
29413527-1	2018	The N-methyl-d-aspartate receptor (NMDAR) is unique in requiring two agonists to bind simultaneously to open its cation channel: the neurotransmitter, glutamate, and the coagonists, glycine, or d-serine.	Glycine	182-189	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	35-40
29413527-9	2018	d-cycloserine, a partial agonist at the NMDAR glycine modulatory site, shows therapeutic benefit for treating pathologic anxiety in combination with behavioral therapies.	Glycine	46-53	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	40-45
29439248-0	2018	Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons.	Glycine	72-79	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	0-40
29122497-10	2018	We alert clinicians to consider the ISCA2 defect as a differential diagnosis of infantile onset leukodystrophies affecting the brain as well as the spinal cord, especially in the presence of elevated CSF glycine or elevated glycine peaks in MR spectroscopy.	Glycine	204-211	iron-sulfur cluster assembly 2	Homo sapiens	36-41
29122497-10	2018	We alert clinicians to consider the ISCA2 defect as a differential diagnosis of infantile onset leukodystrophies affecting the brain as well as the spinal cord, especially in the presence of elevated CSF glycine or elevated glycine peaks in MR spectroscopy.	Glycine	224-231	iron-sulfur cluster assembly 2	Homo sapiens	36-41
28939329-3	2017	Activation of NMDAR depends on simultaneous binding of the GluN2 subunit by glutamate, and of the GluN1 subunit by d-serine or glycine; d-serine is believed to be an endogenous ligand of NMDAR.	Glycine	127-134	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	14-19
28939329-3	2017	Activation of NMDAR depends on simultaneous binding of the GluN2 subunit by glutamate, and of the GluN1 subunit by d-serine or glycine; d-serine is believed to be an endogenous ligand of NMDAR.	Glycine	127-134	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	98-103
20301460-0	1993	Primary Hyperoxaluria Type 1 CLINICAL CHARACTERISTICS: Primary hyperoxaluria type 1 (PH1) is caused by a deficiency of the liver peroxisomal enzyme alanine:glyoxylate-aminotransferase (AGT), which catalyzes the conversion of glyoxylate to glycine.	Glycine	239-246	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	85-88
20301460-0	1993	Primary Hyperoxaluria Type 1 CLINICAL CHARACTERISTICS: Primary hyperoxaluria type 1 (PH1) is caused by a deficiency of the liver peroxisomal enzyme alanine:glyoxylate-aminotransferase (AGT), which catalyzes the conversion of glyoxylate to glycine.	Glycine	239-246	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	148-183
30965876-9	2017	We show that mixtures of DPPC and Me2PE-Gly(2C16)C32-OH form large lamellar aggregates at pH of 5, 7, and 10.	Glycine	40-43	chemokine like factor	Homo sapiens	49-52
28925102-8	2017	BA profile skewed toward a potentially toxic profile (higher secondary and glycine-conjugated BAs) in duodenal fluid and stool in Alc patients.	Glycine	75-82	allantoicase	Homo sapiens	130-133
28906593-3	2017	Multiple mitochondrial dysfunction syndrome 1 (MMDS1) arises as a result of the missense mutation in NFU1, an Fe/S cluster scaffold protein, which substitutes a glycine near the Fe/S cluster-binding pocket to a cysteine (p.Gly208Cys).	Glycine	161-168	NFU1 iron-sulfur cluster scaffold	Homo sapiens	47-52
28906593-3	2017	Multiple mitochondrial dysfunction syndrome 1 (MMDS1) arises as a result of the missense mutation in NFU1, an Fe/S cluster scaffold protein, which substitutes a glycine near the Fe/S cluster-binding pocket to a cysteine (p.Gly208Cys).	Glycine	161-168	NFU1 iron-sulfur cluster scaffold	Homo sapiens	101-105
28906593-9	2017	Rather, replacement of the glycine at position 208 changes the oligomerization state as a result of global structural alterations that result in the downstream effects manifest as MMDS1, but does not perturb the coordination chemistry of the Fe-S cluster.	Glycine	27-34	NFU1 iron-sulfur cluster scaffold	Homo sapiens	180-185
28994430-2	2017	Here, novel multifunctional zero-dimensional-two-dimensional (0D-2D) RGD-QD-MoS2 nanosheets (NSs) with excellent fluorescence, photothermal conversion, and cancer-targeting properties were successfully prepared by functionalizing single-layer MoS2 NSs with fluorescent quantum dots (QDs) and arginine-glycine-aspartic (RGD) containing peptides.	Glycine	301-308	mago homolog, exon junction complex core component	Mus musculus	76-80
28551440-2	2017	Human Dihydrofolate reductase (hDHFR), an enzyme involved in the synthesis of purine, thymidilate and several other amino acids like glycine, methionine and serine is highly aggregation prone.	Glycine	133-140	dihydrofolate reductase	Homo sapiens	6-29
28551440-2	2017	Human Dihydrofolate reductase (hDHFR), an enzyme involved in the synthesis of purine, thymidilate and several other amino acids like glycine, methionine and serine is highly aggregation prone.	Glycine	133-140	dihydrofolate reductase	Homo sapiens	31-36
28854955-4	2017	Comparative analyses of their genomic variations and proliferation characteristics identified a single mutation within the S2" cleavage site between C30 and C40 mutants: the substitution of conserved arginine (R) by a glycine (G) (R895G).	Glycine	218-225	CCR4-NOT transcription complex subunit 11	Homo sapiens	157-160
28784756-9	2017	In Glra2-/Y animals, GlyR tonic currents were preserved; however, the amplitudes of current responses to exogenous glycine were significantly reduced.	Glycine	115-122	glycine receptor, alpha 2 subunit	Mus musculus	3-8
28317339-1	2017	HLA-B*15:01:23 has 1 synonymous nucleotide change from HLA-B*15:01:01:01 at nucleotide 393 (codon 107 glycine).	Glycine	102-109	major histocompatibility complex, class I, B	Homo sapiens	0-5
28317339-1	2017	HLA-B*15:01:23 has 1 synonymous nucleotide change from HLA-B*15:01:01:01 at nucleotide 393 (codon 107 glycine).	Glycine	102-109	major histocompatibility complex, class I, B	Homo sapiens	55-60
28588452-4	2017	These include a microdeletion (GLRA2 ex8-9) and missense mutations in GLRA2 (p.N109S and p.R126Q) that impair cell-surface expression of GlyR alpha2, and either abolish or markedly reduce sensitivity to glycine.	Glycine	203-210	glycine receptor, alpha 2 subunit	Mus musculus	70-75
28287329-1	2017	The cysteine protease ATG4B cleaves off one or more C-terminal residues of the inactive proform of proteins of the ortholog and paralog LC3 and GABARAP subfamilies of yeast Atg8 to expose a C-terminal glycine that is conjugated to phosphatidylethanolamine during autophagosome formation.	Glycine	201-208	gamma-aminobutyric acid receptor associated protein	Mus musculus	144-151
28229167-0	2017	Mutation in a highly conserved glycine residue in strand 5B of plasminogen activator inhibitor 1 causes polymerisation.	Glycine	31-38	serpin family E member 1	Homo sapiens	63-96
28386066-1	2017	GLYT1-mediated glycine transport is the main cell volume-homeostatic mechanism in mouse eggs and early preimplantation embryos.	Glycine	15-22	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	0-5
28890889-4	2017	The genetic analysis revealed a novel missense c.709G&gt;A mutation in exon 7 of ALDH1A3 (aldehyde dehydrogenase 1 family member A3), causing a substitution of glycine (Gly) to arginine (Arg) at residue 237.	Glycine	160-167	aldehyde dehydrogenase 1 family member A3	Homo sapiens	81-88
28890889-4	2017	The genetic analysis revealed a novel missense c.709G&gt;A mutation in exon 7 of ALDH1A3 (aldehyde dehydrogenase 1 family member A3), causing a substitution of glycine (Gly) to arginine (Arg) at residue 237.	Glycine	160-167	aldehyde dehydrogenase 1 family member A3	Homo sapiens	90-131
28890889-4	2017	The genetic analysis revealed a novel missense c.709G&gt;A mutation in exon 7 of ALDH1A3 (aldehyde dehydrogenase 1 family member A3), causing a substitution of glycine (Gly) to arginine (Arg) at residue 237.	Glycine	169-172	aldehyde dehydrogenase 1 family member A3	Homo sapiens	81-88
28890889-4	2017	The genetic analysis revealed a novel missense c.709G&gt;A mutation in exon 7 of ALDH1A3 (aldehyde dehydrogenase 1 family member A3), causing a substitution of glycine (Gly) to arginine (Arg) at residue 237.	Glycine	169-172	aldehyde dehydrogenase 1 family member A3	Homo sapiens	90-131
28228526-1	2017	We report experimental and computational studies investigating the effects of three osmolytes, trimethylamine N-oxide (TMAO), betaine, and glycine, on the hydrophobic collapse of an elastin-like polypeptide (ELP).	Glycine	139-146	nuclear receptor subfamily 5 group A member 1	Homo sapiens	182-206
28228526-1	2017	We report experimental and computational studies investigating the effects of three osmolytes, trimethylamine N-oxide (TMAO), betaine, and glycine, on the hydrophobic collapse of an elastin-like polypeptide (ELP).	Glycine	139-146	nuclear receptor subfamily 5 group A member 1	Homo sapiens	208-211
27794528-2	2017	The mutation of G486D is located within MCM-box and the glycine at 486 in human MCM4 is conserved in Saccharomyces cerevisiae MCM4 and Sulfolobus solfataricus MCM.	Glycine	56-63	MCM DNA helicase complex subunit MCM4	Saccharomyces cerevisiae S288C	126-130
28130358-5	2017	This was true of identified neuronal subpopulations: neurokinin 1 receptor-expressing (NK1R+) neurons in lamina I were GABA-dominant while protein kinase C gamma-expressing (PKCgamma+) neurons at the lamina IIi-III border were glycine-dominant.	Glycine	227-234	protein kinase C, gamma	Mus musculus	139-183
27817855-8	2017	Our results suggest that genotype in DRD3 Ser9Gly was the main factor determining different doses of DAs and PD patients carrying Gly/Gly genotype require higher doses of pramipexole for effective treatment.	Glycine	46-49	dopamine receptor D3	Homo sapiens	37-41
27817855-8	2017	Our results suggest that genotype in DRD3 Ser9Gly was the main factor determining different doses of DAs and PD patients carrying Gly/Gly genotype require higher doses of pramipexole for effective treatment.	Glycine	130-133	dopamine receptor D3	Homo sapiens	37-41
28011762-6	2017	After prolonged fasting, IDH1-null mice exhibited decreased blood glucose but elevated blood alanine and glycine compared with wild-type (WT) controls.	Glycine	105-112	isocitrate dehydrogenase 1 (NADP+), soluble	Mus musculus	25-29
28060902-12	2017	Our results suggest that conjugated bile acids (glycine and taurine) are preferred to unconjugated bile acids as substrates for OATP1B1 and OATP1B3.	Glycine	48-55	solute carrier organic anion transporter family member 1B1	Homo sapiens	128-135
28628911-6	2017	A diagnosis of CARASIL was made with the finding of a novel homozygous missense mutation c.616G&gt;A in HTRA1 gene, resulting in change from Glycine to Arginine in the Serine Protease HTRA1.	Glycine	141-148	HtrA serine peptidase 1	Homo sapiens	104-109
28628911-6	2017	A diagnosis of CARASIL was made with the finding of a novel homozygous missense mutation c.616G&gt;A in HTRA1 gene, resulting in change from Glycine to Arginine in the Serine Protease HTRA1.	Glycine	141-148	HtrA serine peptidase 1	Homo sapiens	184-189
27802239-7	2017	Genetic testing revealed a heterozygous guanine to cytosine mutation at the first base of codon 389 (c.1165G>A) of MAPT, the tau gene, resulting in a glycine to arginine substitution in the patient and two unaffected relatives.	Glycine	150-157	microtubule associated protein tau	Homo sapiens	115-119
27802239-7	2017	Genetic testing revealed a heterozygous guanine to cytosine mutation at the first base of codon 389 (c.1165G>A) of MAPT, the tau gene, resulting in a glycine to arginine substitution in the patient and two unaffected relatives.	Glycine	150-157	microtubule associated protein tau	Homo sapiens	125-128
29358954-8	2017	Results: Npnt mediates hDPSC adhesion and spreading partially via the Arg-Gly-Asp (RGD) motif.	Glycine	74-77	nephronectin	Homo sapiens	9-13
27839948-4	2016	We investigated the functional impact of two natural anemia-causing glycine-to-arginine mutations that impaired transition metal transport in both human Nramp2 and DraNramp.	Glycine	68-75	solute carrier family 11 member 2	Homo sapiens	153-159
27796528-2	2016	We performed site-directed mutational analysis of three key amino acid residues that are glycine in the conserved site for the N-terminal myristoylation, a conserved glutamic acid residue responsible for Ca2+ binding in the third EF-hand (EF3), and an unusual non-conserved amino acid arginine at position 175 in the Neurospora crassa NCS-1.	Glycine	89-96	neuronal calcium sensor 1	Rattus norvegicus	335-340
27296677-4	2016	Recently, DMG has been found acting at glycine binding site of the N-methyl-d-aspartate receptor (NMDAR).	Glycine	39-46	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	67-96
27296677-4	2016	Recently, DMG has been found acting at glycine binding site of the N-methyl-d-aspartate receptor (NMDAR).	Glycine	39-46	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	98-103
27741237-2	2016	Transforming growth factor-beta-inducible gene-h3 (betaig-h3), which consists of four fas-1 domains and an Arg-Gly-Asp (RGD) motif, intensifies inflammatory processes by facilitating adhesion and migration of fibroblast-like synoviocyte in the pathogenesis of rheumatoid arthritis (RA).	Glycine	111-114	transforming growth factor, beta induced	Mus musculus	51-60
27296115-0	2016	BDNF modulates glycine uptake in hippocampal synaptosomes by decreasing membrane insertion of glycine transporter 2.	Glycine	15-22	solute carrier family 6 member 5	Rattus norvegicus	94-115
27296115-1	2016	Glycine transporter 2 (GlyT2) is localized in the nerve terminals of glycinergic neurons, promoting glycine uptake and ensuring the refilling of glycinergic vesicles.	Glycine	69-76	solute carrier family 6 member 5	Rattus norvegicus	0-21
27296115-1	2016	Glycine transporter 2 (GlyT2) is localized in the nerve terminals of glycinergic neurons, promoting glycine uptake and ensuring the refilling of glycinergic vesicles.	Glycine	69-76	solute carrier family 6 member 5	Rattus norvegicus	23-28
27296115-4	2016	We herein show that BDNF decreases [(3)H]glycine uptake mediated by GlyT2 in isolated nerve endings (synaptosomes) obtained from rat hippocampus, by reducing the maximum velocity (Vmax) of transport while not influencing the transporter affinity constant (Km) for glycine.	Glycine	41-48	solute carrier family 6 member 5	Rattus norvegicus	68-73
27296115-6	2016	Monensin, a transporter recycling inhibitor, prevented the BDNF action upon glycine uptake, suggesting that BDNF reduces GlyT2 insertion in the plasma membrane.	Glycine	76-83	solute carrier family 6 member 5	Rattus norvegicus	121-126
27684555-5	2016	Codon usage at these glycines is highly conserved in KRAS compared to HRAS, indicating selective pressure.	Glycine	21-29	HRas proto-oncogene, GTPase	Homo sapiens	70-74
27426256-4	2016	PAM, which converts glycine-extended peptides into amidated products, requires copper and zinc to support its two catalytic activities and calcium for structure.	Glycine	20-27	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	0-3
27225947-0	2016	Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.	Glycine	0-7	toll like receptor 4	Homo sapiens	106-110
27225947-8	2016	In addition, glycine restored the phosphorylation of Akt, mammalian target of rapamycin (mTOR), eukaryotic initiation factor 4E binding protein 1 (4E-BP1), and Forkhead Box O 1 (FOXO1) in gastrocnemius or LD muscles.	Glycine	13-20	eukaryotic translation initiation factor 4E binding protein 1	Homo sapiens	147-153
27442350-9	2016	The transition-state structures, activation Gibbs free energies, and reaction rates calculated using DFT/B3LYP and MP2 for the transformations from the most stable cis G-G and trans Oo-G conformers to trans G-G ones for the first time reveal several alternate coordination-mode transformation mechanisms in the copper(II) complexes with amino acids other than glycine.	Glycine	360-367	tryptase pseudogene 1	Homo sapiens	115-118
26506510-2	2016	Among them the Na(+) -K(+) -2Cl(-) co-transporter (NKCC1) is responsible for intracellular chloride accumulation in most immature brain structures, whereas the K(+) -Cl(-) co-transporter (KCC2) extrudes chloride from mature neurons, ensuring chloride-mediated inhibitory effects of GABA/glycine.	Glycine	287-294	solute carrier family 12 member 2	Homo sapiens	51-56
27382199-3	2016	A variant in the LPL gene has been identified which alters the penultimate amino acid Serine at 447 to a stop codon (S447X), and results in a truncated LPL molecule lacking the C-terminal dipeptide Ser-Gly.	Glycine	202-205	lipoprotein lipase	Homo sapiens	17-20
27382199-3	2016	A variant in the LPL gene has been identified which alters the penultimate amino acid Serine at 447 to a stop codon (S447X), and results in a truncated LPL molecule lacking the C-terminal dipeptide Ser-Gly.	Glycine	202-205	lipoprotein lipase	Homo sapiens	152-155
27348126-6	2016	Mutation of the glycine residue at the position 164 markedly abrogated the TF coagulant activity, resulting in ~90% inhibition.	Glycine	16-23	coagulation factor III, tissue factor	Homo sapiens	75-77
26854734-8	2016	These data support the suggestion that the effectiveness of pharmacological doses of pyridoxine results from an improved metabolic effectiveness of AGT; that is the increased rate of transamination of glyoxylate to glycine.	Glycine	215-222	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	148-151
26951258-5	2016	RESULTS: To the best of our knowledge, the parC mutation Glu(84)-Gly was observed for the first time in S. typhi in India.	Glycine	65-68	cullin 9	Homo sapiens	43-47
27127184-6	2016	Our results highlighted the induction of genes involved in mitochondrial biogenesis (TFAM, NRF1), mitochondrial fusion (MFN1, MFN2) and glycine production (GCAT) during reprogramming.	Glycine	136-143	glycine C-acetyltransferase	Homo sapiens	156-160
27029941-0	2016	Glycine Regulates Expression and Distribution of Claudin-7 and ZO-3 Proteins in Intestinal Porcine Epithelial Cells.	Glycine	0-7	tight junction protein 3	Homo sapiens	63-67
27029941-12	2016	A glycine concentration of 0.25 mmol/L sustained the localization of claudin-7 and ZO-3 to the interface between enterocytes.	Glycine	2-9	tight junction protein 3	Homo sapiens	83-87
27029941-13	2016	Interestingly, 1 mmol glycine/L promoted the distribution of claudin-4 and claudin-7 to the cytosol and nucleus, and the localization of ZO-3 to the plasma membranes, while decreasing the distribution of ZO-1 at cell-cell contact sites, compared with control cells.	Glycine	22-29	tight junction protein 3	Homo sapiens	137-141
27029941-14	2016	CONCLUSION: Physiologic concentrations of glycine support intestinal mucosal barrier function by regulating the abundance and distribution of claudin-7 and ZO-3 in enterocytes.	Glycine	42-49	tight junction protein 3	Homo sapiens	156-160
26708157-5	2016	This COL4A2 (c.2399G&gt;A, p.G800E, CCDS41907.1) variant was predicted to be damaging by multiple bioinformatics tools and affects an invariable glycine residue that is essential for the formation of collagen IV heterotrimers.	Glycine	145-152	collagen type IV alpha 2 chain	Homo sapiens	5-11
26833794-3	2016	D-amino acid oxidase (DAO) degrades neutral D-amino acids such as D-serine, the primary endogenous co-agonist acting at the glycine site of the synaptic NMDAR.	Glycine	124-131	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	153-158
27000430-4	2016	Here, we show that extracellular acidification strongly potentiated glycine-gated currents from recombinant GluN1/GluN3A receptors, with half-maximal effect in the physiologic pH range.	Glycine	68-75	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	114-120
27014692-5	2016	Current research associates this need for Thr with threonine dehydrogenase (TDH), which catabolizes Thr to glycine and acetyl-CoA in mES cells.	Glycine	107-114	L-threonine dehydrogenase (pseudogene)	Homo sapiens	51-74
27014692-5	2016	Current research associates this need for Thr with threonine dehydrogenase (TDH), which catabolizes Thr to glycine and acetyl-CoA in mES cells.	Glycine	107-114	L-threonine dehydrogenase (pseudogene)	Homo sapiens	76-79
26797133-1	2016	Glycyl-tRNA synthetase (GlyRS) is the enzyme that covalently links glycine to cognate tRNA for translation.	Glycine	67-74	glycyl-tRNA synthetase 1	Homo sapiens	0-22
26797133-1	2016	Glycyl-tRNA synthetase (GlyRS) is the enzyme that covalently links glycine to cognate tRNA for translation.	Glycine	67-74	glycyl-tRNA synthetase 1	Homo sapiens	24-29
27047750-8	2016	A charge-relay system between three charged residues as well as apposing glycines in two alpha-helices, both contributed to by motif A, become engaged when PCFT is modeled on the outward-open state of a putative proton-driven transporter (YajR).	Glycine	73-81	solute carrier family 46 member 1	Homo sapiens	156-160
27158326-0	2016	Ameliorative effects of glycine in an experimental nonalcoholic steatohepatitis and its correlation between TREM-1 and TREM-2.	Glycine	24-31	triggering receptor expressed on myeloid cells 1	Homo sapiens	108-114
26881185-2	2016	Due to the presence of the recognition unit GGH (Gly-Gly-His), the probe C-GGH can coordinate with Cu(2+) and consequently display ON-OFF type fluorescence response.	Glycine	49-52	gamma-glutamyl hydrolase	Homo sapiens	44-47
26881185-2	2016	Due to the presence of the recognition unit GGH (Gly-Gly-His), the probe C-GGH can coordinate with Cu(2+) and consequently display ON-OFF type fluorescence response.	Glycine	49-52	gamma-glutamyl hydrolase	Homo sapiens	75-78
26881185-2	2016	Due to the presence of the recognition unit GGH (Gly-Gly-His), the probe C-GGH can coordinate with Cu(2+) and consequently display ON-OFF type fluorescence response.	Glycine	53-56	gamma-glutamyl hydrolase	Homo sapiens	44-47
26818177-7	2016	We found that the N-terminal glycine repeat of eRF3a influences eRF3a-PABP interaction and that eRF3a 12-GGC allele has a decreased binding affinity for PABP.	Glycine	29-36	poly(A) binding protein cytoplasmic 1	Homo sapiens	70-74
26511319-6	2015	Although wild-type ALAS catalyzes the conversion of ALA into the quinonoid intermediate at a rate 6.3-fold slower than the formation of the same quinonoid intermediate from glycine and succinyl-CoA, the N150F variant catalyzes the forward reaction at a mere 1.2-fold faster rate than that of the reverse reaction, and the N150H variant reverses the rate values with a 1.7-fold faster rate for the reverse reaction than that for the forward reaction.	Glycine	173-180	aminolevulinic acid synthase 1	Mus musculus	19-23
26176428-2	2015	Candidate gene screening has uncovered a novel and private polymorphism in the Oji-Cree population in the hepatocyte nuclear factor-1 alpha (HNF-1alpha) gene, where a highly conserved glycine residue at position 319 is changed to a serine (termed HNF-1alphaG319S or simply G319S).	Glycine	184-191	HNF1 homeobox A	Mus musculus	106-139
26176428-2	2015	Candidate gene screening has uncovered a novel and private polymorphism in the Oji-Cree population in the hepatocyte nuclear factor-1 alpha (HNF-1alpha) gene, where a highly conserved glycine residue at position 319 is changed to a serine (termed HNF-1alphaG319S or simply G319S).	Glycine	184-191	HNF1 homeobox A	Mus musculus	141-151
26108146-0	2015	Novel compound heterozygous LIAS mutations cause glycine encephalopathy.	Glycine	49-56	lipoic acid synthetase	Homo sapiens	28-32
26456780-7	2015	In addition, N-Calpha bond cleavage forming the z1 ion was observed in the ETD spectra of Trp-GlyCa(2+) (18C6) and Gly-TrpCa(2+) (18C6).	Glycine	94-97	CEA cell adhesion molecule 6	Homo sapiens	13-21
26059756-3	2015	GSH is synthesized from glutamic acid, cysteine, and glycine via two sequential ATP-consuming steps, which are catalyzed by glutamate cysteine ligase (GCL) and GSH synthetase (GSS).	Glycine	53-60	glutathione synthetase	Homo sapiens	160-174
26048991-8	2015	The function of conRl-B was examined by measuring its inhibition of NMDA/Gly-mediated current through NMDAR ion channels in mouse cortical neurons.	Glycine	73-76	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	102-107
25877470-7	2015	Transport activity of the glycine-to-leucine mutants correlated with surface hPCFT by surface biotinylation and confocal microscopy with ECFP*-tagged hPCFTs, suggesting a role for GXXXG in hPCFT stability and intracellular trafficking.	Glycine	26-33	solute carrier family 46 member 1	Homo sapiens	77-82
25877470-7	2015	Transport activity of the glycine-to-leucine mutants correlated with surface hPCFT by surface biotinylation and confocal microscopy with ECFP*-tagged hPCFTs, suggesting a role for GXXXG in hPCFT stability and intracellular trafficking.	Glycine	26-33	solute carrier family 46 member 1	Homo sapiens	150-155
25442010-3	2015	Through DNA sequencing and the PCR-single-strand conformation polymorphism method, a novel 9-bp nucleotide insertion (+) or deletion (-) was detected on exon 2 of SFTPA1, which causes a change in three amino acids, namely, alanine (Ala), glycine (Gly) and proline (Pro).	Glycine	238-245	pulmonary surfactant-associated protein A	Sus scrofa	163-169
25442010-3	2015	Through DNA sequencing and the PCR-single-strand conformation polymorphism method, a novel 9-bp nucleotide insertion (+) or deletion (-) was detected on exon 2 of SFTPA1, which causes a change in three amino acids, namely, alanine (Ala), glycine (Gly) and proline (Pro).	Glycine	247-250	pulmonary surfactant-associated protein A	Sus scrofa	163-169
26000717-4	2015	Microarray screening revealed that epigenetic downregulation of the nuclear-coded GCAT gene, which is involved in glycine production in mitochondria, is partly responsible for these aging phenotypes.	Glycine	114-121	glycine C-acetyltransferase	Homo sapiens	82-86
25616961-6	2015	The interacting region in each of these proteins was their glycine-rich domain, the domain most frequently mutated in hnRNP-related proteins that cause ALS.	Glycine	59-66	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	118-123
25418841-0	2015	Glycine bidirectionally regulates ischemic tolerance via different mechanisms including NR2A-dependent CREB phosphorylation.	Glycine	0-7	cAMP responsive element binding protein 1	Rattus norvegicus	103-107
25418841-10	2015	(a) Under low dose of Gly pre-treatment, glycine induces NMDAR potentiation and CREB-dependent neuroprotection through the NMDAR co-agonist binding site.	Glycine	22-25	cAMP responsive element binding protein 1	Rattus norvegicus	80-84
25418841-10	2015	(a) Under low dose of Gly pre-treatment, glycine induces NMDAR potentiation and CREB-dependent neuroprotection through the NMDAR co-agonist binding site.	Glycine	41-48	cAMP responsive element binding protein 1	Rattus norvegicus	80-84
27499898-5	2015	We found that H3.3 mutations, namely mutations of glycine 34 in H3F3A, occur in 96% of GCT.	Glycine	50-57	H3.3 histone A	Homo sapiens	64-69
25614284-6	2015	Blockade of fibrin polymerization with 5 mmol/L Gly-Pro-Arg-Pro dysregulated hemostasis by enhancing both P-selectin(+) core size and clot size at 400 s(-1) (20 mm Hg).	Glycine	48-51	selectin P	Homo sapiens	106-116
25677305-2	2015	Serine hydroxymethyltransferase (SHMT), the enzyme providing one-carbon units by converting serine and tetrahydrofolate (H4 PteGlu) to glycine and 5,10-CH2 -H4 PteGlu, therefore represents a target of interest in developing new chemotherapeutic drugs.	Glycine	135-142	serine hydroxymethyltransferase 1	Homo sapiens	0-31
25677305-2	2015	Serine hydroxymethyltransferase (SHMT), the enzyme providing one-carbon units by converting serine and tetrahydrofolate (H4 PteGlu) to glycine and 5,10-CH2 -H4 PteGlu, therefore represents a target of interest in developing new chemotherapeutic drugs.	Glycine	135-142	serine hydroxymethyltransferase 1	Homo sapiens	33-37
25391768-11	2015	This is probably because the additional glycine residues present at the N-terminus of hCCL2 following TEV digestion interfere with the binding of hCCL2 to its receptor.	Glycine	40-47	C-C motif chemokine ligand 2	Homo sapiens	86-91
25391768-11	2015	This is probably because the additional glycine residues present at the N-terminus of hCCL2 following TEV digestion interfere with the binding of hCCL2 to its receptor.	Glycine	40-47	C-C motif chemokine ligand 2	Homo sapiens	146-151
25625371-3	2015	Cow milk opioid peptides, including beta-casomorphin-7 (BCM7, Tyr-Pro-Phe-Pro-Gly-Pro-Ile), affect the mu-opioid receptor (MOR) and are subjected to degradation resulting from the proline dipeptidyl peptidase IV (DPPIV, EC 3.4.14.5) enzyme activity.	Glycine	78-81	opioid receptor mu 1	Homo sapiens	123-126
25758857-4	2015	Our case clearly suggests the importance of considering NFU1 mutation in slowly evolving leukoencephalopathy with high glycine concentration.	Glycine	119-126	NFU1 iron-sulfur cluster scaffold	Homo sapiens	56-60
25399070-5	2015	An adenosine to guanine transversion was identified in exon 2 that changes a highly conserved glutamic acid residue in the SOX10 DNA binding domain to glycine.	Glycine	151-158	SRY-box transcription factor 10	Homo sapiens	123-128
25301276-1	2015	Inhibitory glycinergic neurotransmission is terminated by the specific glycine transporters GlyT1 and GlyT2 which actively reuptake glycine from the synaptic cleft.	Glycine	11-18	solute carrier family 6 member 9 L homeolog	Xenopus laevis	92-97
25301276-2	2015	GlyT1 is associated with both glycinergic and glutamatergic pathways, and is the main regulator of the glycine levels in the synapses.	Glycine	30-37	solute carrier family 6 member 9 L homeolog	Xenopus laevis	0-5
25382260-3	2015	The QM/MM simulations show that when the original isoleucine residue is substituted in silico by valine, alanine, or glycine (I14V, I14A, and I14G DHFR, respectively), the free energy barrier height of the hydride transfer reaction increases relative to the wild-type enzyme.	Glycine	117-124	dihydrofolate reductase	Homo sapiens	147-151
25550512-6	2015	During postnatal development, the replacement of GluN2B- by GluN2A-containing NMDARs at SC-CA1 synapses parallels a change in the identity of the coagonist from glycine to D-serine.	Glycine	161-168	carbonic anhydrase 1	Rattus norvegicus	91-94
23968838-7	2015	Importantly, we demonstrate that treatment with NMDAR co-agonists (glycine or D-serine) independently rescue impairments in NMDAR-dependent synaptic plasticity in the DG of the Fragile X mental retardation 1 (Fmr1) knockout mouse.	Glycine	67-74	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	48-53
23968838-7	2015	Importantly, we demonstrate that treatment with NMDAR co-agonists (glycine or D-serine) independently rescue impairments in NMDAR-dependent synaptic plasticity in the DG of the Fragile X mental retardation 1 (Fmr1) knockout mouse.	Glycine	67-74	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	124-129
25731620-8	2015	In conditions involving down regulated GSH homeostasis, GGC serves as a crucialrate-limiting substrate for GSH synthetase, the main enzyme responsible for condensing glycine with GGC to form the final thiol tripeptide, GSH.	Glycine	166-173	glutathione synthetase	Homo sapiens	107-121
25218309-1	2015	The synthetic 15-mer arginine-glycine-aspartic acid (RGD) domain of osteopontin (OPN) is protective in vitro and in vivo against dopaminergic cell death and this protective effect may be mediated through interaction with integrin receptors to regulate neurotrophic factor levels.	Glycine	30-37	neurotrophin 3	Rattus norvegicus	252-271
26226965-8	2015	In the present study in the archaeon H. salinarum, it was shown that both the N and C-2 from glycine are incorporated into the thiazole, rather than the N atom coming from L-tyrosine.	Glycine	93-100	complement C2	Homo sapiens	84-87
26327585-1	2015	The canonical activity of glycyl-tRNA synthetase (GARS) is to charge glycine onto its cognate tRNAs.	Glycine	69-76	glycyl-tRNA synthetase 1	Homo sapiens	26-48
26327585-1	2015	The canonical activity of glycyl-tRNA synthetase (GARS) is to charge glycine onto its cognate tRNAs.	Glycine	69-76	glycyl-tRNA synthetase 1	Homo sapiens	50-54
25486018-0	2014	Pharmacological PPARalpha activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat.	Glycine	88-95	peroxisome proliferator activated receptor alpha	Rattus norvegicus	16-25
25103283-6	2014	The GlyT1-specific inhibitor sarcosine reduced the maximal glycine-induced current (IGly (max) ) by about 60%.	Glycine	59-66	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	4-9
25419572-2	2014	OPN primarily exerts its functions through interaction with integrins via the Arg-Gly-Asp and Ser-Val-Val-Tyr-Gly-Leu-Arg sequences located in the N-terminal part of the protein.	Glycine	82-85	secreted phosphoprotein 1	Homo sapiens	0-3
25419572-2	2014	OPN primarily exerts its functions through interaction with integrins via the Arg-Gly-Asp and Ser-Val-Val-Tyr-Gly-Leu-Arg sequences located in the N-terminal part of the protein.	Glycine	110-113	secreted phosphoprotein 1	Homo sapiens	0-3
25305483-4	2014	The GABA, glycine and serotonin transporters showed unique binding preferences scattered over one or several MUPP1 domains.	Glycine	10-17	multiple PDZ domain crumbs cell polarity complex component	Homo sapiens	109-114
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	0-7	aminomethyltransferase	Homo sapiens	191-213
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	0-7	aminomethyltransferase	Homo sapiens	215-218
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	48-55	aminomethyltransferase	Homo sapiens	191-213
25231368-1	2014	Glycine encephalopathy (GCE) or nonketotic hyperglycinemia is an inborn error of glycine metabolism, inherited in an autosomal recessive manner due to a defect in any one of the four enzymes aminomethyltransferase (AMT), glycine decarboxylase (GLDC), glycine cleavage system protein-H (GCSH) and dehydrolipoamide dehydrogenase in the glycine cleavage system.	Glycine	81-88	aminomethyltransferase	Homo sapiens	191-213
25452113-6	2014	It is positively modulated by d-serine acting on the glycine site of NMDA receptors and blocked by AP5 (2-amino-5-phosphono propionate) in the three structures.	Glycine	53-60	adaptor related protein complex 5 subunit beta 1	Homo sapiens	99-102
25310961-14	2014	A significant effect of interaction of carrying both IRS-1 Gly/Arg and IRS-2 Asp/Asp was also observed in the non-obese PCOS patients (p = 0.003), but not in the obese PCOS patients.	Glycine	59-62	insulin receptor substrate 1	Homo sapiens	53-58
25160622-8	2014	In AtCM1, mutations of Gly-213 abolish allosteric regulation, as observed in AtCM2.	Glycine	23-26	chorismate mutase 1	Arabidopsis thaliana	3-8
25160622-8	2014	In AtCM1, mutations of Gly-213 abolish allosteric regulation, as observed in AtCM2.	Glycine	23-26	chorismate mutase 2	Arabidopsis thaliana	77-82
25160622-9	2014	A second effector site position, Gly-149 in AtCM1 and Asp-132 in AtCM3, controls amino acid effector specificity in AtCM1 and AtCM3.	Glycine	33-36	chorismate mutase 1	Arabidopsis thaliana	44-49
25160622-9	2014	A second effector site position, Gly-149 in AtCM1 and Asp-132 in AtCM3, controls amino acid effector specificity in AtCM1 and AtCM3.	Glycine	33-36	chorismate mutase 1	Arabidopsis thaliana	116-121
25229620-6	2014	In the present study, we expressed and purified recombinant human endostatin (rhEndostatin) that contained 3 additional amino acid residues (arginine, glycine, and serine) at the amino-terminus and 6 histidine residues in its carboxyl terminus.	Glycine	151-158	collagen type XVIII alpha 1 chain	Homo sapiens	66-76
25053765-7	2014	Determination of the methylation activity of the expressed wild-type (WT) and variant TRMT10A enzymes with transcripts of (32)P -tRNA(Gly) GCC as a substrate revealed a striking defect (&lt;0.1% of WT activity) for the variant enzyme.	Glycine	134-137	tRNA methyltransferase 10A	Homo sapiens	86-93
25079194-4	2014	We generated a GS mutant that catalyzes azido-Ala in place of Gly with high catalytic efficiency and selectivity.	Glycine	62-65	glutathione synthetase	Homo sapiens	15-17
25214272-4	2014	The conducted researches results have shown reliably higher frequency of heterozygous genotype Asp/Gly TLR-4 in patients with grippe (12,69%) and grippe-associated pneumonia (14,28%) compared with population control (3,33%).	Glycine	99-102	toll like receptor 4	Homo sapiens	103-108
29245219-9	2017	We discovered a heterozygous substitution in STK11, c.A527G in exon 4, in the girl and her father who was also a PJS patient, and the amine acid change was an aspartic acid-glycine substitution in codon 176.	Glycine	173-180	serine/threonine kinase 11	Homo sapiens	45-50
27757771-9	2017	The glycine survival rate followed the order SAz-1 &gt; SAz-1-Na &gt; STx-1   NAu-1 &gt; KGa-1.	Glycine	4-11	syntaxin 1A	Homo sapiens	70-75
2792654-1	1989	The biosynthesis of biologically active gastrin and cholecystokinin (CCK) requires the formation of carboxyl-terminally amidated peptides from glycine-extended precursors of gastrin and CCK.	Glycine	143-150	gastrin	Homo sapiens	40-47
2792654-1	1989	The biosynthesis of biologically active gastrin and cholecystokinin (CCK) requires the formation of carboxyl-terminally amidated peptides from glycine-extended precursors of gastrin and CCK.	Glycine	143-150	gastrin	Homo sapiens	174-181
2792654-2	1989	In previous studies we and others have identified and characterized glycine-extended forms of gastrin (Ggly) and CCK (CCK-gly) in the human gastrointestinal tract.	Glycine	68-75	gastrin	Homo sapiens	94-101
24561070-1	2014	Gephyrin is a postsynaptic scaffolding protein, essential for the clustering of glycine and gamma-aminobutyric acid type-A receptors (GABAARs) at inhibitory synapses.	Glycine	80-87	gephyrin	Homo sapiens	0-8
2677400-5	1989	Our results indicate that a glutamic acid to glycine change at gp120 amino acid 516, a lysine to isoleucine change at amino acid 517, and an arginine to lysine change at amino acid 518 affect neither gp160 cleavage nor syncytium formation.	Glycine	45-52	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	63-68
24692659-3	2014	We report that in addition to the C-terminal region of hnRNP G, the RNA Recognition Motif (RRM) and the middle part of the protein containing the Arg-Gly-Gly (RGG) box are important for this function.	Glycine	150-153	RBMX pseudogene 1	Homo sapiens	55-62
2550669-3	1989	Thus, the behavior of Pr76gag in mammalian cells is much like that of mammalian retroviral Gag proteins which have been altered so as to block the addition of myristic acid at residue 2 (Gly).	Glycine	187-190	Pr76 polyprotein precursor	Rous sarcoma virus	91-94
24692659-3	2014	We report that in addition to the C-terminal region of hnRNP G, the RNA Recognition Motif (RRM) and the middle part of the protein containing the Arg-Gly-Gly (RGG) box are important for this function.	Glycine	154-157	RBMX pseudogene 1	Homo sapiens	55-62
24520911-0	2014	Mutations to a glycine loop in the catalytic site of human Lon changes its protease, peptidase and ATPase activities.	Glycine	15-22	lon peptidase 1, mitochondrial	Homo sapiens	59-62
2736523-1	1989	We investigated that the antimetastatic and antiadhesive activities of peptides based on Arg-Gly-Asp adhesive signal in fibronectin could be augmented by their polymerization.	Glycine	93-96	fibronectin 1	Mus musculus	120-131
24633419-11	2014	Moreover, PEPT1 was saturated with Gly-Sar at a concentration of 2.5 mM.	Glycine	35-38	solute carrier family 15 member 1	Bos taurus	10-15
2499585-7	1989	The glycine mutant, developed so that steric hindrance or other unfavorable interactions at the modified active site would be minimal, was similarly incapable of forming complexes with PAI-1.	Glycine	4-11	serpin family E member 1	Homo sapiens	185-190
2472353-6	1989	The 600 glycine and the 601 lysine were involved in the binding of all IgG1, 2 and 4 and most IgG3.	Glycine	8-15	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	94-98
2539593-4	1989	A ubiquitin-N alpha-protein hydrolase has been partially purified from rabbit reticulocytes; this enzyme faithfully cleaves the junction peptide bound between the C-terminal Gly-76 of ubiquitin and the fusion protein.	Glycine	174-177	ubiquitin	Oryctolagus cuniculus	2-11
2539593-4	1989	A ubiquitin-N alpha-protein hydrolase has been partially purified from rabbit reticulocytes; this enzyme faithfully cleaves the junction peptide bound between the C-terminal Gly-76 of ubiquitin and the fusion protein.	Glycine	174-177	ubiquitin	Oryctolagus cuniculus	184-193
2646950-10	1989	Perfusing an isolated segment of small bowel in situ with glycine for 2 h also increased immunoreactive ODC but only in the villus cells.	Glycine	58-65	ornithine decarboxylase 1	Rattus norvegicus	104-107
2707256-5	1989	Substitution of proline for the alanine-713 residue and substitution of glutamine for the glycine-717 residue converted EF-2 to partially toxin-resistant forms.	Glycine	90-97	eukaryotic translation elongation factor 2	Mus musculus	120-124
2669815-1	1989	Substitutions of amino acids for Gly 12 or Gly 13 in the ras oncogene-encoded P21 proteins have been demonstrated to produce unique structural changes in these proteins that correlate with their ability to produce cell transformation.	Glycine	33-36	H3 histone pseudogene 16	Homo sapiens	78-81
2669815-1	1989	Substitutions of amino acids for Gly 12 or Gly 13 in the ras oncogene-encoded P21 proteins have been demonstrated to produce unique structural changes in these proteins that correlate with their ability to produce cell transformation.	Glycine	43-46	H3 histone pseudogene 16	Homo sapiens	78-81
2698313-4	1989	The cDNA sequence indicated the presence of a Gly-Arg-Gly-Asp-Ser- (GRGDS) amino acid sequence identical to a cell binding sequence in fibronectin, and suggested that osteopontin might function as a cell attachment factor.	Glycine	46-49	secreted phosphoprotein 1	Homo sapiens	167-178
28780732-2	2017	Although direct agonism of the NMDAR has not yielded promising therapeutics, advances have been made by modulating the NMDAR co-agonist site which is activated by glycine and D-serine.	Glycine	163-170	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	119-124
2698313-4	1989	The cDNA sequence indicated the presence of a Gly-Arg-Gly-Asp-Ser- (GRGDS) amino acid sequence identical to a cell binding sequence in fibronectin, and suggested that osteopontin might function as a cell attachment factor.	Glycine	54-57	secreted phosphoprotein 1	Homo sapiens	167-178
2852323-2	1988	The evoked population spike response in the CA1 region following activation of the Schaffer collateral and commissural afferents was increased following perfusion with the delta-selective agonist [D-Pen2,D-Pen5]enkephalin (DPDPE), and with the mu-selective agonist [D-Ala2,NMe-Phe4,Gly(O)5ol]enkephalin (DAGO).	Glycine	282-285	carbonic anhydrase 1	Rattus norvegicus	44-47
29073064-0	2017	Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.	Glycine	39-46	serine hydroxymethyltransferase 1	Homo sapiens	6-10
29073064-1	2017	The enzyme serine hydroxymethyltransferse (SHMT) converts serine into glycine and a tetrahydrofolate-bound one-carbon unit.	Glycine	70-77	serine hydroxymethyltransferase 1	Homo sapiens	11-41
29073064-1	2017	The enzyme serine hydroxymethyltransferse (SHMT) converts serine into glycine and a tetrahydrofolate-bound one-carbon unit.	Glycine	70-77	serine hydroxymethyltransferase 1	Homo sapiens	43-47
29073064-9	2017	We show that this effect is rooted in defective glycine uptake in DLBCL cell lines, rendering them uniquely dependent upon SHMT enzymatic activity to meet glycine demand.	Glycine	48-55	serine hydroxymethyltransferase 1	Homo sapiens	123-127
29073064-9	2017	We show that this effect is rooted in defective glycine uptake in DLBCL cell lines, rendering them uniquely dependent upon SHMT enzymatic activity to meet glycine demand.	Glycine	155-162	serine hydroxymethyltransferase 1	Homo sapiens	123-127
2852323-2	1988	The evoked population spike response in the CA1 region following activation of the Schaffer collateral and commissural afferents was increased following perfusion with the delta-selective agonist [D-Pen2,D-Pen5]enkephalin (DPDPE), and with the mu-selective agonist [D-Ala2,NMe-Phe4,Gly(O)5ol]enkephalin (DAGO).	Glycine	282-285	proenkephalin	Rattus norvegicus	211-221
3242846-7	1988	The CPA of GNCP preparation was not blocked by the antiserum and scarcely inhibited in the presence of the synthetic cell attachment-promoting peptide Gly-Arg-Gly-Asp-Ser-Pro, a competitive inhibitor of fibronectin.	Glycine	151-154	fibronectin 1	Mus musculus	203-214
28850877-6	2017	Within the data sets of peptides predicted to lie in coil regions, both hPAD2 and hPAD4 appear to favor citrullination of glycine-containing motifs, while distinct hydrophobic motifs were identified for hPAD2 citrullination sites predicted to reside within alpha-helical and beta-sheet regions.	Glycine	122-129	peptidyl arginine deiminase 4	Homo sapiens	82-87
3242846-7	1988	The CPA of GNCP preparation was not blocked by the antiserum and scarcely inhibited in the presence of the synthetic cell attachment-promoting peptide Gly-Arg-Gly-Asp-Ser-Pro, a competitive inhibitor of fibronectin.	Glycine	159-162	fibronectin 1	Mus musculus	203-214
2848850-7	1988	Attachment of all four cell types is also markedly inhibited by the synthetic peptides gly-arg-gly-asp-ser-pro (GRG-DSP) and gly-arg-gly-asp-ala-cys (GRGDAC) but not by the control peptide gly-arg-gly-glu-ser-pro (GRG-ESP).	Glycine	87-90	TLE family member 5, transcriptional modulator	Homo sapiens	112-115
2848850-7	1988	Attachment of all four cell types is also markedly inhibited by the synthetic peptides gly-arg-gly-asp-ser-pro (GRG-DSP) and gly-arg-gly-asp-ala-cys (GRGDAC) but not by the control peptide gly-arg-gly-glu-ser-pro (GRG-ESP).	Glycine	87-90	TLE family member 5, transcriptional modulator	Homo sapiens	150-153
3680281-2	1987	Using radioimmunoassays for amidated and glycine-extended gastrin before and after trypsin-carboxypeptidase B cleavage and chromatography, alpha-carboxyamidation of porcine antral progastrin has been related to tyrosine-O-sulfation and proteolytic cleavages.	Glycine	41-48	gastrin	Homo sapiens	58-65
3680281-6	1987	For instance, gastrin-34-Gly constituted 54% of the glycine-extended gastrins, while gastrin-34 comprised 8% of the amidated gastrins.	Glycine	52-59	gastrin	Homo sapiens	14-21
3680281-6	1987	For instance, gastrin-34-Gly constituted 54% of the glycine-extended gastrins, while gastrin-34 comprised 8% of the amidated gastrins.	Glycine	52-59	gastrin	Homo sapiens	69-76
3688881-5	1987	Gly-Gly cleavage by cathepsin L was blocked by D-Ala2, did not require the presence of free end groups, and was the only site recognized within opioid peptides having a C-terminal Arg-COOH.	Glycine	0-3	cathepsin L	Rattus norvegicus	20-31
3688881-5	1987	Gly-Gly cleavage by cathepsin L was blocked by D-Ala2, did not require the presence of free end groups, and was the only site recognized within opioid peptides having a C-terminal Arg-COOH.	Glycine	4-7	cathepsin L	Rattus norvegicus	20-31
3305015-14	1987	The results reveal that Glu-Gly (residues 34-35), Glu-Ala (residues 42-43) and Glu-Leu (residues 50-51) are three preferential cleavage sites for V8 protease and their cleavage, especially the Glu-Ala and the Glu-Leu sites, was drastically inhibited when antithrombin III was preincubated with heparin.	Glycine	28-31	serpin family C member 1	Homo sapiens	255-271
2956270-2	1987	Whereas the Ba F3 cell line, which has both immunoglobulin heavy- and light-chain genes in germline configuration, interacts with the arg-gly-asp-containing cell-binding domain of fibronectin, the B-committed line PD 31, which is undergoing rearrangement of immunoglobulin light-chain genes, does not.	Glycine	138-141	fibronectin 1	Mus musculus	180-191
3569767-2	1987	Gel filtration of antral and duodenal extracts on Sephadex G-50 revealed multiple molecular forms of immunoreactive glycine-extended processing intermediates corresponding to known molecular forms of gastrin and cholecystokinin.	Glycine	116-123	gastrin	Homo sapiens	200-207
3569767-3	1987	Immunoaffinity chromatography studies of antral mucosal and gastrinoma extracts identified a molecular form of glycine-extended processing intermediates that was characterized by an amino terminus identical to that of gastrin heptadecapeptide.	Glycine	111-118	gastrin	Homo sapiens	60-67
3569767-5	1987	These studies suggest the potential importance of glycine-extended peptides as intermediates in the posttranslational processing of gastrin and cholecystokinin in humans and indicate that gastrin processing mechanisms may be altered in Zollinger-Ellison tumors.	Glycine	50-57	gastrin	Homo sapiens	132-139
3109687-6	1987	The Met-enkephalin-Arg-Gly-Leu levels are affected by VPA administration in a more complex pattern.	Glycine	23-26	proenkephalin	Rattus norvegicus	8-18
3548429-1	1987	Less than Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, the luteinizing hormone-releasing hormone, LHRH, is degraded in renal proximal tubules (PT) in vivo (rat) and in vitro (rabbit) to less than Glu-His (2), less than Glu-His-Trp (3), and less than Glu-His-Trp-Ser (4).	Glycine	30-33	gonadotropin releasing hormone 1	Rattus norvegicus	59-96
3548429-1	1987	Less than Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, the luteinizing hormone-releasing hormone, LHRH, is degraded in renal proximal tubules (PT) in vivo (rat) and in vitro (rabbit) to less than Glu-His (2), less than Glu-His-Trp (3), and less than Glu-His-Trp-Ser (4).	Glycine	30-33	gonadotropin releasing hormone 1	Rattus norvegicus	98-102
3548429-4	1987	[D-Ser4]LHRH was not cleaved at D Ser4-Tyr5 but yielded less than Glu-His-Trp-D-Ser-Tyr-Gly as the major metabolite plus 2 and 3.	Glycine	88-91	gonadotropin releasing hormone 1	Rattus norvegicus	8-12
3035402-1	1987	Chronic hyperphenylalaninemia maintained with the aid of a suppressor of phenylalanine hydroxylase, alpha-methylphenylalanine, increases the glycine concentration and the phosphoserine phosphatase activity of the developing rat brain but not that of liver or kidney.	Glycine	141-148	phenylalanine hydroxylase	Rattus norvegicus	73-98
3805128-4	1987	For fibronectin, Gly-Arg-Gly-Asp-Ser was considerably more active than Arg-Gly-Asp-Ser, whereas these two peptides displayed little difference in activity in inhibiting cell adhesion to spreading factor.	Glycine	17-20	fibronectin 1	Gallus gallus	4-15
24388924-5	2014	Our data identify the 1Na(+):1K(+):2Cl(-) cotransporter 1 (NKCC1) as the major Cl(-)-loader responsible for depolarizing action of GABA/glycine at postnatal days 3-5 (P3-5).	Glycine	136-143	solute carrier family 12 member 2	Homo sapiens	59-64
24498414-6	2014	ERGIC-53 has a shallower sugar-binding pocket than VIP36 because of the single amino acid substitution, Asp-to-Gly.	Glycine	111-114	lectin, mannose binding 2	Homo sapiens	51-56
3490906-3	1986	Normal p21 contains glycine at position 12; the other amino acid substitutions are those which would result from a single base change in codon 12 and may therefore be the activating mutations most likely to occur in human tumors.	Glycine	20-27	H3 histone pseudogene 16	Homo sapiens	7-10
23877191-4	2014	The missense mutation changes glutamic acid (GAA) to glycine (GGA).	Glycine	53-60	lysosomal alpha-glucosidase	Ovis aries	45-48
3023389-7	1986	The synthetic peptide Gly-Arg-Gly-Asp-Ser derived from the sequence of the cell-binding region of fibronectin could also prevent the organization of fibronectin-140K linkage complexes.	Glycine	22-25	fibronectin 1	Gallus gallus	98-109
3023389-7	1986	The synthetic peptide Gly-Arg-Gly-Asp-Ser derived from the sequence of the cell-binding region of fibronectin could also prevent the organization of fibronectin-140K linkage complexes.	Glycine	22-25	fibronectin 1	Gallus gallus	149-160
24510571-5	2014	HQ873871) has differed from HLA-B*33:03:01 by one nucleotide in exon 4, which resulted in nt 866 G  A substitution, which results in an amino acid substitution from Gly(GGT) to Asp(GAT) at codon 265.	Glycine	165-168	major histocompatibility complex, class I, B	Homo sapiens	28-33
28760597-1	2017	Serine hydroxymethyltransferase (SHMT), an essential enzyme for cell growth and development, catalyzes the transfer of -CH2OH from l-serine to tetrahydrofolate (THF) to form glycine and 5,10-methylenetetrahydrofolate (MTHF) which is used for nucleotide synthesis.	Glycine	174-181	serine hydroxymethyltransferase 1	Homo sapiens	0-31
3023389-7	1986	The synthetic peptide Gly-Arg-Gly-Asp-Ser derived from the sequence of the cell-binding region of fibronectin could also prevent the organization of fibronectin-140K linkage complexes.	Glycine	30-33	fibronectin 1	Gallus gallus	98-109
28760597-1	2017	Serine hydroxymethyltransferase (SHMT), an essential enzyme for cell growth and development, catalyzes the transfer of -CH2OH from l-serine to tetrahydrofolate (THF) to form glycine and 5,10-methylenetetrahydrofolate (MTHF) which is used for nucleotide synthesis.	Glycine	174-181	serine hydroxymethyltransferase 1	Homo sapiens	33-37
3023389-7	1986	The synthetic peptide Gly-Arg-Gly-Asp-Ser derived from the sequence of the cell-binding region of fibronectin could also prevent the organization of fibronectin-140K linkage complexes.	Glycine	30-33	fibronectin 1	Gallus gallus	149-160
2430952-5	1986	The N-terminal 9 amino acid sequence of soybean beta-amylase was deduced to be acetyl-Ala-Thr-Ser-Asp-Ser-Asn-Met-(Gly-Leu) from the results of sequence analysis of Pep-4 and amino acid analysis of other acidic peptides.	Glycine	115-118	beta-amylase	Glycine max	48-60
30135938-2	2017	Glycine transporter 2 (GLYT2) is responsible for the uptake of extracellular glycine.	Glycine	77-84	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	0-21
30135938-2	2017	Glycine transporter 2 (GLYT2) is responsible for the uptake of extracellular glycine.	Glycine	77-84	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	23-28
24392144-6	2014	Hmgn5(tm1/Y) mice had a significant increase in hepatic glutathione levels and decreased urinary concentrations of betaine, phenylacetylglycine, and creatine, all of which are metabolically related to the glutathione precursor glycine.	Glycine	136-143	high-mobility group nucleosome binding domain 5	Mus musculus	0-5
2942550-8	1986	Finally, the tetrapeptide Arg-Gly-Asp-Ser, which corresponds to the fibronectin sequence recognized by fibroblastic cells, specifically and competitively inhibited attachment of hemopoietic cells to this molecule.	Glycine	30-33	fibronectin 1	Mus musculus	68-79
24078189-0	2014	Quantitative determination of glycine in aqueous solution using glutamate dehydrogenase-immobilized glyoxal agarose beads.	Glycine	30-37	glutamate dehydrogenase 1	Homo sapiens	64-87
24078189-1	2014	In this study, an enzymatic procedure for the determination of glycine (Gly) was developed by using a column containing immobilized glutamate dehydrogenase (GDH) on glyoxal agarose beads.	Glycine	63-70	glutamate dehydrogenase 1	Homo sapiens	132-155
24078189-1	2014	In this study, an enzymatic procedure for the determination of glycine (Gly) was developed by using a column containing immobilized glutamate dehydrogenase (GDH) on glyoxal agarose beads.	Glycine	63-70	glutamate dehydrogenase 1	Homo sapiens	157-160
24078189-1	2014	In this study, an enzymatic procedure for the determination of glycine (Gly) was developed by using a column containing immobilized glutamate dehydrogenase (GDH) on glyoxal agarose beads.	Glycine	72-75	glutamate dehydrogenase 1	Homo sapiens	132-155
24078189-1	2014	In this study, an enzymatic procedure for the determination of glycine (Gly) was developed by using a column containing immobilized glutamate dehydrogenase (GDH) on glyoxal agarose beads.	Glycine	72-75	glutamate dehydrogenase 1	Homo sapiens	157-160
28792792-6	2017	In this regard, the sequences of six new synthetic IL-24s that have been modified by RGD (Arg-Gly-Asp) or NGR (CRNGRGPDC) were aligned and their structures were modeled through homology modeling to evaluate their attachment potential to cognate receptor complexes such as IL-20R1/IL-20R2, IL-22R1/IL-20R2, or Sig1R.	Glycine	94-97	interleukin 24	Homo sapiens	51-56
28740143-4	2017	The gene SLC25A38, responsible for transporting glycine from cytoplasm to mitochondria, and the gene ALAS1, encoding rate-limiting enzyme (delta-aminolevulinic acid synthase 1), had higher expression at 15 hr, as compared with 2, 5 and 23.5 hrs postoviposition.	Glycine	48-55	5'-aminolevulinate synthase 1	Gallus gallus	101-106
25036958-5	2014	Additionally, point mutagenesis analysis showed that the substitution of Asp by Gly within the Pro-Val-Asp-Leu-Thr (PVDLT) motif of gKLF3 significantly reduced the ability of gKLF3 to regulate the promoter activities of FABP4, FASN, LPL, C/EBPalpha, and PPARgamma.	Glycine	80-83	fatty acid synthase	Gallus gallus	227-231
3733872-5	1986	The fourth (GP1.5) is a glycine-rich species that binds to the interior of the in vitro crystal; it is apparently equivalent to the granules within the W4 layer in situ.	Glycine	24-31	uncharacterized protein	Chlamydomonas reinhardtii	12-15
28532685-3	2017	The purpose of this paper is to address the inhibition of protein disulfide isomerase (PDI), an essential redox chaperone whose active sites contain the Cys-Gly-His-Cys (CXXC) motif, by the nitroxide Tempol.	Glycine	157-160	prolyl 4-hydroxylase, beta polypeptide	Mus musculus	58-85
28532685-3	2017	The purpose of this paper is to address the inhibition of protein disulfide isomerase (PDI), an essential redox chaperone whose active sites contain the Cys-Gly-His-Cys (CXXC) motif, by the nitroxide Tempol.	Glycine	157-160	prolyl 4-hydroxylase, beta polypeptide	Mus musculus	87-90
2871767-8	1986	Unilateral lesions involving the C1 area or phenylethanolamine-N-methyltransferase-labeled descending axons derived from this area imparied by greater than 70% the response to ipsilateral application of L-glutamate, GABA, or glycine to the ventral surface.	Glycine	225-232	phenylethanolamine-N-methyltransferase	Rattus norvegicus	44-82
28649199-3	2017	GLYX-13 is a NMDAR modulator with glycine site partial agonist properties and has potential protective effects on ischemic neuronal death.	Glycine	34-41	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	13-18
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	maternally expressed 3	Mus musculus	74-101
3088682-2	1986	Peptides related to thyrotropin releasing hormone (TRH) were identified in the eluted fractions by trypsin digestion and radioimmunoassay (RIA) using antibodies to the TRH tripeptide pGlu-His-Pro amide or to a TRH-related pentapeptide pGlu-His-Pro-Gly-Lys.	Glycine	248-251	thyrotropin-releasing hormone L homeolog	Xenopus laevis	20-49
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	maternally expressed 3	Mus musculus	103-107
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	retrotransposon Gaglike 1	Mus musculus	150-154
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	deiodinase, iodothyronine type III	Mus musculus	225-229
28273511-0	2017	A Glycine max homolog of NON-RACE SPECIFIC DISEASE RESISTANCE 1 (NDR1) alters defense gene expression while functioning during a resistance response to different root pathogens in different genetic backgrounds.	Glycine	2-9	Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family	Arabidopsis thaliana	25-63
3088682-2	1986	Peptides related to thyrotropin releasing hormone (TRH) were identified in the eluted fractions by trypsin digestion and radioimmunoassay (RIA) using antibodies to the TRH tripeptide pGlu-His-Pro amide or to a TRH-related pentapeptide pGlu-His-Pro-Gly-Lys.	Glycine	248-251	thyrotropin-releasing hormone L homeolog	Xenopus laevis	51-54
28273511-0	2017	A Glycine max homolog of NON-RACE SPECIFIC DISEASE RESISTANCE 1 (NDR1) alters defense gene expression while functioning during a resistance response to different root pathogens in different genetic backgrounds.	Glycine	2-9	Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family	Arabidopsis thaliana	65-69
3088682-5	1986	Evidence was also obtained for the presence of small amounts of the TRH-related pentapeptide pGlu-His-Pro-Gly-Lys.	Glycine	106-109	thyrotropin-releasing hormone L homeolog	Xenopus laevis	68-71
28273511-1	2017	A Glycine max homolog of the Arabidopsis thaliana NON-RACE SPECIFIC DISEASE RESISTANCE 1 (NDR1) coiled-coil nucleotide binding leucine rich repeat (CC-NB-LRR) defense signaling gene (Gm-NDR1-1) is expressed in root cells undergoing a defense response to the root pathogenic nematode, Heterodera glycines.	Glycine	2-9	Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family	Arabidopsis thaliana	50-88
28273511-1	2017	A Glycine max homolog of the Arabidopsis thaliana NON-RACE SPECIFIC DISEASE RESISTANCE 1 (NDR1) coiled-coil nucleotide binding leucine rich repeat (CC-NB-LRR) defense signaling gene (Gm-NDR1-1) is expressed in root cells undergoing a defense response to the root pathogenic nematode, Heterodera glycines.	Glycine	2-9	Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family	Arabidopsis thaliana	90-94
28273511-1	2017	A Glycine max homolog of the Arabidopsis thaliana NON-RACE SPECIFIC DISEASE RESISTANCE 1 (NDR1) coiled-coil nucleotide binding leucine rich repeat (CC-NB-LRR) defense signaling gene (Gm-NDR1-1) is expressed in root cells undergoing a defense response to the root pathogenic nematode, Heterodera glycines.	Glycine	2-9	Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family	Arabidopsis thaliana	186-190
2936685-6	1986	The binding of cryptococcal TsF1 to the cryptococcal SPIA column was shown to be specific since Sepharose 4B columns either coupled with Saccharomyces cerevisiae mannan or blocked with glycine did not adsorb the suppressor activity.	Glycine	185-192	serine/threonine kinase 16	Homo sapiens	28-32
28219903-2	2017	Using integrated gene expression and metabolite profiling, we identify six pathways that are coordinately deregulated in primary MYC-driven liver tumors: glutathione metabolism; glycine, serine, and threonine metabolism; aminoacyl-tRNA biosynthesis; cysteine and methionine metabolism; ABC transporters; and mineral absorption.	Glycine	178-185	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	129-132
3000358-9	1985	This glycine residue is located in the middle of the triple-helical regions found in C1q at exactly the position where there is an unusual structural feature, i.e. a bend in each of the helical regions brought about by the interruption of the Gly-Xaa-Yaa repeating triplet sequences in the A- and C-chains and the presence of an "extra" triplet in the B-chain.	Glycine	5-12	complement C1q A chain	Homo sapiens	85-88
28188302-10	2017	In human VAChT, residue 360 is located in a conserved region and substitution of arginine for glycine is predicted to disrupt proper protein folding and membrane embedding.	Glycine	94-101	solute carrier family 18 member A3	Homo sapiens	9-14
3933841-6	1985	The cysteinylglycyl conjugate (AFB1-Cys.Gly) was prepared by incubating the AFB1-GSH conjugate with a rat hepatoma cell line rich in gamma-glutamyl-transpeptidase (GGT).	Glycine	40-43	gamma-glutamyltransferase 1	Rattus norvegicus	133-162
28122914-6	2017	NDR2 contains the PTS1-like sequence, Gly-Lys-Leu, at the C-terminal end, whereas the C-terminal end of NDR1 is Ala-Lys.	Glycine	38-41	serine/threonine kinase 38 like	Homo sapiens	0-4
4044659-6	1985	None of these four peptides contains the tetrapeptide sequence Arg-Gly-Asp-Ser, which has been associated with fibronectin-mediated cell adhesion.	Glycine	67-70	fibronectin 1	Rattus norvegicus	111-122
27838364-4	2017	Hsp47 recognizes collagenous (Gly-Xaa-Arg) repeats on triple-helical procollagen and can prevent local unfolding and/or aggregate formation of procollagen.	Glycine	30-33	serine (or cysteine) peptidase inhibitor, clade H, member 1	Mus musculus	0-5
28828604-5	2017	The five additional glycine transporters ATB0,+, SNAT1, SNAT2, SNAT5, and LAT2 display broad amino acid specificity and have differential contributions to glial glycine transport.	Glycine	20-27	solute carrier family 38 member 1	Homo sapiens	49-54
4044546-5	1985	Intestinal ODC was induced by intragastric but not intraperitoneal injection of glycine, although these treatments resulted in similar increases in the tissue concentration of glycine.	Glycine	176-183	ornithine decarboxylase 1	Rattus norvegicus	11-14
27785568-2	2017	In the last years, mutations in four genes (NFU1, BOLA3, ISCA2 and IBA57) have been related to a new group of multiple mitochondrial dysfunction syndromes characterized by lactic acidosis, hyperglycinemia, multiple defects of the respiratory chain complexes, and impairment of four lipoic acid-dependent enzymes: alpha-ketoglutarate dehydrogenase complex, pyruvic dehydrogenase, branched-chain alpha-keto acid dehydrogenase complex and the H protein of the glycine cleavage system.	Glycine	194-201	NFU1 iron-sulfur cluster scaffold	Homo sapiens	44-48
27785568-2	2017	In the last years, mutations in four genes (NFU1, BOLA3, ISCA2 and IBA57) have been related to a new group of multiple mitochondrial dysfunction syndromes characterized by lactic acidosis, hyperglycinemia, multiple defects of the respiratory chain complexes, and impairment of four lipoic acid-dependent enzymes: alpha-ketoglutarate dehydrogenase complex, pyruvic dehydrogenase, branched-chain alpha-keto acid dehydrogenase complex and the H protein of the glycine cleavage system.	Glycine	194-201	bolA family member 3	Homo sapiens	50-55
27785568-2	2017	In the last years, mutations in four genes (NFU1, BOLA3, ISCA2 and IBA57) have been related to a new group of multiple mitochondrial dysfunction syndromes characterized by lactic acidosis, hyperglycinemia, multiple defects of the respiratory chain complexes, and impairment of four lipoic acid-dependent enzymes: alpha-ketoglutarate dehydrogenase complex, pyruvic dehydrogenase, branched-chain alpha-keto acid dehydrogenase complex and the H protein of the glycine cleavage system.	Glycine	194-201	iron-sulfur cluster assembly 2	Homo sapiens	57-62
4044546-6	1985	On the contrary, hepatic ODC was induced by glycine regardless of the administration route.	Glycine	44-51	ornithine decarboxylase 1	Rattus norvegicus	25-28
3889695-3	1985	The enzyme specifically cleaved the Lys-Arg bonds of two synthetic peptides containing the subsequence of proenkephalin A, but endogenous opioid peptides containing a single basic residue in the molecule [Met)enk-Arg-Phe, (Met)enk-Arg-Gly-Leu) were not affected by the enzyme.	Glycine	235-238	proenkephalin	Bos taurus	106-121
27860107-6	2016	Using Tet21N human neuroblastoma cells, we also found that Myc(oncogene)-induced metabolic reprogramming included a higher rate of metabolizing Gly, which provides additional evidence that the metabolism of proliferating cells is adapted to facilitate producing new cells.	Glycine	144-147	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	59-62
3881277-4	1985	In the amino acid sequence predicted by the IGF-II variant cDNA, the Ser residue 29 in the B-domain has been replaced by an Arg-Leu-Pro-Gly sequence.	Glycine	136-139	insulin like growth factor 2	Homo sapiens	44-50
27633914-2	2016	Serine racemase knockout (SR-/-) mice have less than 15% of wild type forebrain levels of D-serine, whereas glycine transporter 1 heterozygous knockout (GlyT1+/-) mice have elevated synaptic glycine.	Glycine	108-115	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	153-158
6327184-6	1984	The purified trypsin-activated fibroblast collagenase hydrolyzed type I collagen fibrils, cleaved tropocollagen in solution at 24 degrees C into TCA and TCB fragments, and cleaved the synthetic peptide substrate, DNP-peptide III, at the Gly-Ile bond.	Glycine	237-240	matrix metallopeptidase 1	Homo sapiens	31-53
27799657-3	2016	By developing genetically engineered mouse models and primary pancreatic epithelial cells, and employing transcriptional, proteomics, and metabolic analyses, we find that oncogenic cooperation between LKB1 loss and KRAS activation is fuelled by pronounced mTOR-dependent induction of the serine-glycine-one-carbon pathway coupled to S-adenosylmethionine generation.	Glycine	295-302	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	215-219
27799657-3	2016	By developing genetically engineered mouse models and primary pancreatic epithelial cells, and employing transcriptional, proteomics, and metabolic analyses, we find that oncogenic cooperation between LKB1 loss and KRAS activation is fuelled by pronounced mTOR-dependent induction of the serine-glycine-one-carbon pathway coupled to S-adenosylmethionine generation.	Glycine	295-302	mechanistic target of rapamycin kinase	Mus musculus	256-260
27773429-0	2016	Loss of Glycine Transporter 1 Causes a Subtype of Glycine Encephalopathy with Arthrogryposis and Mildly Elevated Cerebrospinal Fluid Glycine.	Glycine	50-57	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	8-29
27773429-2	2016	Two transporters, GLYT1 and GLYT2, regulate extracellular glycine concentrations within the CNS.	Glycine	58-65	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	18-23
27773429-2	2016	Two transporters, GLYT1 and GLYT2, regulate extracellular glycine concentrations within the CNS.	Glycine	58-65	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	28-33
16593407-5	1984	The tRNA(Gly) and tRNA(Arg) deduced from the DNA sequences show 84% and 55% sequence homologies with Escherichia coli tRNA(Gly) (UCC) and phage T4 tRNA(Arg) (UCU), respectively.	Glycine	9-12	trnY(gua)	Nicotiana tabacum	4-8
27773429-8	2016	We demonstrate that pharmacologic or genetic abolishment of GlyT1 activity in mice leads to mildly elevated glycine in the CSF but not in blood.	Glycine	108-115	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	60-65
6387881-8	1984	Furthermore, a C-terminal glycine extended component, corresponding to each of the other molecular forms of gastrin were present.	Glycine	26-33	gastrin	Homo sapiens	108-115
27395790-1	2016	Glycine can be substrate for two transporters: GlyT1, largely expressed by astrocytes but also by some non-glycinergic neurons, and GlyT2, most frequently present in glycine-storing nerve endings.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	47-52
27395790-1	2016	Glycine can be substrate for two transporters: GlyT1, largely expressed by astrocytes but also by some non-glycinergic neurons, and GlyT2, most frequently present in glycine-storing nerve endings.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	132-137
27395790-1	2016	Glycine can be substrate for two transporters: GlyT1, largely expressed by astrocytes but also by some non-glycinergic neurons, and GlyT2, most frequently present in glycine-storing nerve endings.	Glycine	107-114	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	47-52
27395790-7	2016	Moreover, GlyT2 transporters could perform Na(+)-dependent homoexchange in response to externally added glycine.	Glycine	104-111	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	10-15
27395790-9	2016	Although glycine release through GlyT2 had been predicted to be a very difficult process, GlyT2 expressed on isolated glycinergic nerve terminals can perform both release by transporter reversal and homoexchange.	Glycine	9-16	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	90-95
27502273-8	2016	Using protease cleavage-predicting software and site-directed mutagenesis, we identified that calpain-1 cleaves hERG at position Gly-603 in the S5-pore linker of hERG.	Glycine	129-132	calpain 1	Homo sapiens	94-103
27225947-10	2016	Moreover, glycine resulted in decreased mRNA expresson of Toll-like receptor 4 (TLR4), nucleotide-binding oligomerization domain protein 2 (NOD2), and their respective downstream molecules in gastrocnemius or LD muscles.	Glycine	10-17	toll like receptor 4	Homo sapiens	58-78
6667476-2	1983	spectroscopy was used to study the mode of binding of Gd3+ to mono-O-glycosylated L-serine and tripeptides variously composed of Gly and L-Thr.	Glycine	129-132	GRDX	Homo sapiens	54-57
27225947-10	2016	Moreover, glycine resulted in decreased mRNA expresson of Toll-like receptor 4 (TLR4), nucleotide-binding oligomerization domain protein 2 (NOD2), and their respective downstream molecules in gastrocnemius or LD muscles.	Glycine	10-17	toll like receptor 4	Homo sapiens	80-84
27225947-12	2016	The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.	Glycine	24-31	toll like receptor 4	Homo sapiens	145-149
6638727-4	1983	Newly recognized molecular defects in osteogenesis imperfecta include the diminished formation of type I collagen and alpha-1[I] messenger RNA; abnormal synthesis or faulty assembly of alpha-2[I]; deletion or insertion of base pairs in the gene for alpha-1[I] or alpha-2[I] and failure to secrete type I procollagen; and substitution of cysteine for glycine in the triple helix.	Glycine	350-357	adrenoceptor alpha 1D	Homo sapiens	249-256
27235905-9	2016	Dietary supplementation of glycine increased the anti-oxidative ability of tilapia through increase anti-oxidative enzyme activity (SOD, glutathione reductase, myeloperoxidase) and up-regulate anti-oxidative gene expression (SOD).	Glycine	27-34	superoxide dismutase [Mn], mitochondrial	Oreochromis niloticus	132-135
27235905-9	2016	Dietary supplementation of glycine increased the anti-oxidative ability of tilapia through increase anti-oxidative enzyme activity (SOD, glutathione reductase, myeloperoxidase) and up-regulate anti-oxidative gene expression (SOD).	Glycine	27-34	superoxide dismutase [Mn], mitochondrial	Oreochromis niloticus	225-228
6863283-2	1983	Chicken liver P-protein of the multienzyme glycine cleavage system catalyzes the first partial reaction of glycine cleavage.	Glycine	43-50	OCA2 melanosomal transmembrane protein	Gallus gallus	14-23
26768609-2	2016	The NGR (asparagine-glycine-arginine)-containing peptides can specifically bind to CD13 (Aminopeptidase N) receptor which is overexpressed in angiogenic blood vessels and tumor cells.	Glycine	20-27	alanyl (membrane) aminopeptidase	Mus musculus	83-87
26768609-2	2016	The NGR (asparagine-glycine-arginine)-containing peptides can specifically bind to CD13 (Aminopeptidase N) receptor which is overexpressed in angiogenic blood vessels and tumor cells.	Glycine	20-27	alanyl (membrane) aminopeptidase	Mus musculus	89-105
6863283-2	1983	Chicken liver P-protein of the multienzyme glycine cleavage system catalyzes the first partial reaction of glycine cleavage.	Glycine	107-114	OCA2 melanosomal transmembrane protein	Gallus gallus	14-23
27264869-4	2016	MDM2 recruitment to chromatin is a tightly regulated process that occurs during oxidative stress and serine/glycine deprivation and is modulated by the pyruvate kinase M2 (PKM2) metabolic enzyme.	Glycine	108-115	transformed mouse 3T3 cell double minute 2	Mus musculus	0-4
6853532-7	1983	Comparison of the 27-residue peptide with the known structure of porcine gastrin-releasing peptide, another bombesin-like heptacosapeptide, reveals four amino acid substitutions: canine bombesin-like peptide had Pro 4, Gly 5, Gln 7, Asp 12, whereas porcine gastrin-releasing peptide had Ser 4, Val 5, Gly 7, Ala 12.	Glycine	219-222	gastrin releasing peptide	Canis lupus familiaris	73-98
27162334-3	2016	Here we show that tubulin tyrosine ligase like-5 (TTLL5) glutamylates RPGR(ORF15) in its Glu-Gly-rich repetitive region containing motifs homologous to the alpha-tubulin C-terminal tail.	Glycine	93-96	tubulin tyrosine ligase-like family, member 5	Mus musculus	18-48
27162334-3	2016	Here we show that tubulin tyrosine ligase like-5 (TTLL5) glutamylates RPGR(ORF15) in its Glu-Gly-rich repetitive region containing motifs homologous to the alpha-tubulin C-terminal tail.	Glycine	93-96	tubulin tyrosine ligase-like family, member 5	Mus musculus	50-55
6679320-3	1983	Further studies on the glycine-14CO2 exchange catalyzed by p-protein and H-protein purified from chicken liver indicated that tiglyl CoA inhibited the activity of P-protein in an apparently competitive manner with respect to H-protein, and that cysteamine inhibited the activity of P-protein in two ways, by increasing the Km value for glycine and changing Vmax.	Glycine	23-30	OCA2 melanosomal transmembrane protein	Gallus gallus	163-172
27147587-4	2016	The bile acids most elevated in the NPC subjects were identified as 3beta,5alpha,6beta-trihydroxycholanic acid and its glycine conjugate, which were shown to be metabolites of cholestane-3beta,5alpha,6beta-triol, an oxysterol elevated in NPC.	Glycine	119-126	NPC intracellular cholesterol transporter 1	Homo sapiens	36-39
6679320-3	1983	Further studies on the glycine-14CO2 exchange catalyzed by p-protein and H-protein purified from chicken liver indicated that tiglyl CoA inhibited the activity of P-protein in an apparently competitive manner with respect to H-protein, and that cysteamine inhibited the activity of P-protein in two ways, by increasing the Km value for glycine and changing Vmax.	Glycine	336-343	OCA2 melanosomal transmembrane protein	Gallus gallus	59-68
6679320-3	1983	Further studies on the glycine-14CO2 exchange catalyzed by p-protein and H-protein purified from chicken liver indicated that tiglyl CoA inhibited the activity of P-protein in an apparently competitive manner with respect to H-protein, and that cysteamine inhibited the activity of P-protein in two ways, by increasing the Km value for glycine and changing Vmax.	Glycine	336-343	OCA2 melanosomal transmembrane protein	Gallus gallus	163-172
6976996-6	1982	C1q contained hydroxyproline, hydroxylysine and high percentage of glycine.	Glycine	67-74	complement C1q A chain	Homo sapiens	0-3
7216818-0	1981	Hemoglobin Handsworth (gamma 18 (A16) Gly leads to Arg) in a Chinese.	Glycine	38-41	immunoglobulin kappa variable 3-31 (pseudogene)	Homo sapiens	33-36
7440562-2	1980	Glycine decarboxylase, tentatively called P-protein and considered a constituent of the glycine cleavage system, was purified to apparent homogeneity from chicken liver mitochondria.	Glycine	88-95	OCA2 melanosomal transmembrane protein	Gallus gallus	42-51
7440562-6	1980	P-protein could bind glycine, showing a Kd of 33 mM for it, and could catalyze glycine decarboxylation even though the rate of decarboxylation catalyzed by P-protein alone was extremely low.	Glycine	21-28	OCA2 melanosomal transmembrane protein	Gallus gallus	0-9
7440562-6	1980	P-protein could bind glycine, showing a Kd of 33 mM for it, and could catalyze glycine decarboxylation even though the rate of decarboxylation catalyzed by P-protein alone was extremely low.	Glycine	79-86	OCA2 melanosomal transmembrane protein	Gallus gallus	0-9
7440562-9	1980	P-protein alone could also slightly catalyze the exchange of carboxyl carbon of glycine with CO2 and the exchange appeared to obey a ping-pong mechanism.	Glycine	80-87	OCA2 melanosomal transmembrane protein	Gallus gallus	0-9
7440562-10	1980	Both glycine decarboxylation and the glycine-CO2 exchange catalyzed by P-protein were stimulated 100-fold or more by the addition of lipoic acid, which is a functional group of H-protein.	Glycine	5-12	OCA2 melanosomal transmembrane protein	Gallus gallus	71-80
7440562-10	1980	Both glycine decarboxylation and the glycine-CO2 exchange catalyzed by P-protein were stimulated 100-fold or more by the addition of lipoic acid, which is a functional group of H-protein.	Glycine	37-44	OCA2 melanosomal transmembrane protein	Gallus gallus	71-80
6261242-4	1980	The steric constraints introduced in H-Tyr-cyclo(-N gamma-D-A2bu-Gly-Phe-Leu-) were shown to prevent the realization of most of the conformational features ascribed to linear enkephalin in solution or in the crystalline state and permitted an assessment of proposed models of the conformation of enkephalin when it is bound to the receptor.	Glycine	65-68	proenkephalin	Rattus norvegicus	175-185
6261242-4	1980	The steric constraints introduced in H-Tyr-cyclo(-N gamma-D-A2bu-Gly-Phe-Leu-) were shown to prevent the realization of most of the conformational features ascribed to linear enkephalin in solution or in the crystalline state and permitted an assessment of proposed models of the conformation of enkephalin when it is bound to the receptor.	Glycine	65-68	proenkephalin	Rattus norvegicus	296-306
7414298-7	1980	A linear regression equation was calculated for the relationship between ELP and erythropoiesis, expressed as the incorportion of glycine into circulating haemoglobin haem.	Glycine	130-137	nuclear receptor subfamily 5 group A member 1	Homo sapiens	73-76
513121-3	1979	caused a transient rise of plasma glycine level, but CSF glycine concentration began to rise only after an injection of 1,000 mg./kg.	Glycine	57-64	colony stimulating factor 2	Homo sapiens	53-56
24358310-8	2013	The resulting hLIF, which contains one extra glycine residue at the N-terminus, was highly pure and demonstrated endotoxin levels below 0.05 EU/mug.	Glycine	45-52	LIF interleukin 6 family cytokine	Homo sapiens	14-18
513121-5	1979	Repetition of the latter dose every four hours for twenty-four hours caused a gradual rise of both plasma and CSF glycine.	Glycine	114-121	colony stimulating factor 2	Homo sapiens	110-113
23973313-1	2013	NMDA receptors are ligand-gated ion channels that assemble into tetrameric receptor complexes composed of glycine-binding GluN1 and GluN3 subunits (GluN3A-B) and glutamate-binding GluN2 subunits (GluN2A-D).	Glycine	106-113	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	148-154
385187-2	1979	Augmentation of the secretion of leucocyte migration inhibitory factor (LIF) by leucocyte dialysate and by its components L-serine and glycine.	Glycine	135-142	LIF interleukin 6 family cytokine	Homo sapiens	33-70
23919636-6	2013	A previously described VGAT mutant (Glu213Ala) that disrupts GABA and glycine transport similarly abrogates beta-alanine uptake.	Glycine	70-77	solute carrier family 32 member 1	Homo sapiens	23-27
23919636-7	2013	These findings indicated that VGAT transports beta-alanine through a mechanism similar to those for GABA and glycine, and functions as a vesicular beta-alanine transporter.	Glycine	109-116	solute carrier family 32 member 1	Homo sapiens	30-34
385187-2	1979	Augmentation of the secretion of leucocyte migration inhibitory factor (LIF) by leucocyte dialysate and by its components L-serine and glycine.	Glycine	135-142	LIF interleukin 6 family cytokine	Homo sapiens	72-75
385187-3	1979	The effect of human transfer factor (TF) or its components L-serine and/or glycine in tuberculin (PPD), or leucoagglutinin (LA) induced leucocyte migration inhibitory factor (LIF) secretion was studied.	Glycine	75-82	LIF interleukin 6 family cytokine	Homo sapiens	175-178
385187-4	1979	Augmentation of LIF secretion was seen with low concentration ( = 0.078 g/l) of TF when lymphocytes were cultured in minimum essential medium for suspension cultures (MEM-S), a culture medium lacking L-serine and glycine.	Glycine	213-220	LIF interleukin 6 family cytokine	Homo sapiens	16-19
385187-7	1979	The combination of L-serine and glycine, at concentrations equivalent or lower than the optimum of TF, had an augmenting effect on LIF secretion identical to that of TF, but no inhibition at higher concentrations was seen.	Glycine	32-39	LIF interleukin 6 family cytokine	Homo sapiens	131-134
23834509-4	2013	Here we compared glycine-mediated conformational changes in alpha1 and alpha3 GlyRs to identify structural differences that might be exploited in designing alpha3-specific analgesics.	Glycine	17-24	glycine receptor alpha 1	Homo sapiens	60-83
83165-4	1979	A collagenase complex with alpha2-macroglobulin did not hydrolyze collagen fibrils, but digested the synthetic substrates at the Gly-Ile bond.	Glycine	129-132	LOW QUALITY PROTEIN: alpha-2-macroglobulin	Oryctolagus cuniculus	27-47
24100323-1	2013	Gephyrin is a trimeric protein involved in the final steps of molybdenum-cofactor (Moco) biosynthesis and in the clustering of inhibitory glycine and GABAA receptors at postsynaptic specializations.	Glycine	138-145	gephyrin	Homo sapiens	0-8
656053-2	1978	We have previously shown that an antigenic site (site 1) in native lysozyme resides around the disulphide bond 6-127 and, by classical synthesis of nine disulphide peptides, the antigenic site was accurately narrowed down to the structure Cys((6))-Arg((14))-[Cys((6))-Cys((127))] -Gly((126))-Arg((128)).	Glycine	281-284	lysozyme C-like	Oryctolagus cuniculus	67-75
23892373-0	2013	Discovery of high frequencies of the Gly-Ile haplotype of TLR4 in Indian populations requires reformulation of the evolutionary model of its maintenance.	Glycine	37-40	toll like receptor 4	Homo sapiens	58-62
656053-10	1978	The surface-simulation synthetic peptide Arg-Gly-Gly-Arg-Gly-Glu-Gly-Gly-Arg-Lys (which does not exist in native lysozyme, but copies a surface region of it) accounted entirely for the maximum expected reactivity of the site (i.e. about one-third of the total antigenic reactivity of lysozyme).	Glycine	45-48	lysozyme C-like	Oryctolagus cuniculus	113-121
23553550-10	2013	Maintenance of cell volume in preimplantation embryos requires glycine accumulation via the GLYT1 transporter, a process unique to eggs and early embryos that is initiated during meiotic maturation.	Glycine	63-70	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	92-97
656053-10	1978	The surface-simulation synthetic peptide Arg-Gly-Gly-Arg-Gly-Glu-Gly-Gly-Arg-Lys (which does not exist in native lysozyme, but copies a surface region of it) accounted entirely for the maximum expected reactivity of the site (i.e. about one-third of the total antigenic reactivity of lysozyme).	Glycine	45-48	lysozyme C-like	Oryctolagus cuniculus	284-292
656053-10	1978	The surface-simulation synthetic peptide Arg-Gly-Gly-Arg-Gly-Glu-Gly-Gly-Arg-Lys (which does not exist in native lysozyme, but copies a surface region of it) accounted entirely for the maximum expected reactivity of the site (i.e. about one-third of the total antigenic reactivity of lysozyme).	Glycine	49-52	lysozyme C-like	Oryctolagus cuniculus	113-121
656053-10	1978	The surface-simulation synthetic peptide Arg-Gly-Gly-Arg-Gly-Glu-Gly-Gly-Arg-Lys (which does not exist in native lysozyme, but copies a surface region of it) accounted entirely for the maximum expected reactivity of the site (i.e. about one-third of the total antigenic reactivity of lysozyme).	Glycine	49-52	lysozyme C-like	Oryctolagus cuniculus	284-292
656053-10	1978	The surface-simulation synthetic peptide Arg-Gly-Gly-Arg-Gly-Glu-Gly-Gly-Arg-Lys (which does not exist in native lysozyme, but copies a surface region of it) accounted entirely for the maximum expected reactivity of the site (i.e. about one-third of the total antigenic reactivity of lysozyme).	Glycine	49-52	lysozyme C-like	Oryctolagus cuniculus	113-121
656053-10	1978	The surface-simulation synthetic peptide Arg-Gly-Gly-Arg-Gly-Glu-Gly-Gly-Arg-Lys (which does not exist in native lysozyme, but copies a surface region of it) accounted entirely for the maximum expected reactivity of the site (i.e. about one-third of the total antigenic reactivity of lysozyme).	Glycine	49-52	lysozyme C-like	Oryctolagus cuniculus	284-292
649256-3	1978	A description is given of the synthesis by fragment condensation of the peptide Gly-Glu-Ser-Arg-Glu-Ser-Ser-Ala-Asp-Lys-Phe-Lys-Arg-Gln-His-Met-Asp-Thr-Glu-Gly-Pro-Ser-Lys corresponding to the 1--23 amino acid sequence of rat pancreatic ribonuclease.	Glycine	80-83	ribonuclease A family member 1, pancreatic	Rattus norvegicus	226-249
24058364-1	2013	Human thioredoxin-1 (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-.	Glycine	96-99	thioredoxin	Homo sapiens	6-19
649256-3	1978	A description is given of the synthesis by fragment condensation of the peptide Gly-Glu-Ser-Arg-Glu-Ser-Ser-Ala-Asp-Lys-Phe-Lys-Arg-Gln-His-Met-Asp-Thr-Glu-Gly-Pro-Ser-Lys corresponding to the 1--23 amino acid sequence of rat pancreatic ribonuclease.	Glycine	156-159	ribonuclease A family member 1, pancreatic	Rattus norvegicus	226-249
24058364-1	2013	Human thioredoxin-1 (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-.	Glycine	96-99	thioredoxin	Homo sapiens	21-24
852596-0	1977	Haemoglobin Handsworth alpha 18 (A16) glycine leads to arginne.	Glycine	38-45	immunoglobulin kappa variable 3-31 (pseudogene)	Homo sapiens	33-36
25702411-1	2013	Linear hepta-peptide Cys-Lys-Gly-Asp-Trp-Asp-Cys was synthesized first and then disulfide bond was formed between the Cys1 and Cys7 to develop cyclo-heptapeptide containing Lys-Gly-Asp-sequence.	Glycine	29-32	cystin 1	Homo sapiens	118-122
320197-1	1977	A new mutation introducing a one-carbon requirement (e.g., formate) for the glycine-supplemented growth of a serine-glycine auxotroph (ser1) was correlated with a lack of glycine decarboxylase activity.	Glycine	76-83	O-phospho-L-serine:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	135-139
320197-1	1977	A new mutation introducing a one-carbon requirement (e.g., formate) for the glycine-supplemented growth of a serine-glycine auxotroph (ser1) was correlated with a lack of glycine decarboxylase activity.	Glycine	116-123	O-phospho-L-serine:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	135-139
7319-0	1976	Oxidation of sarcosine and N-alkyl derivatives of glycine by D-amino-acid oxidase.	Glycine	50-57	D-amino acid oxidase	Homo sapiens	61-81
23578394-1	2013	GluN2D-containing NMDA receptors are characterized by an unusually low open probability (0.023), even in the presence of saturating glutamate and glycine.	Glycine	146-153	glutamate ionotropic receptor NMDA type subunit 2D	Homo sapiens	0-6
1181278-6	1975	b) With purified glutathione synthetase, an enzymatic endpoint metabolite determination was performed with [14C]glycine as one substrate.	Glycine	107-119	glutathione synthetase	Homo sapiens	17-39
23624758-2	2013	These receptors and ligand-gated ion channels activated by structurally simple agonists such as glutamate, glycine and GABA present such a narrow chemical space that the design of subtype-selective molecules capable of distinguishing a dozen of glutamate and GABA receptor subtypes and possessing desirable pharmacokinetic properties has also been problematic.	Glycine	107-114	GABA type A receptor-associated protein	Homo sapiens	259-272
1152307-2	1975	This is a newly developed compound, in which the disulfide bond and [Pro-7] of deamino-oxytocin are substituted by an ethylene linkage and glycine respectively.	Glycine	139-146	oxytocin	Oryctolagus cuniculus	87-95
23606107-8	2013	Several potentially functional rare variants in IL23R were identified, including one nonsynonomous single-nucleotide polymorphism (nsSNP), Gly(149) Arg (position 67421184 GA on chromosome 1).	Glycine	139-142	interleukin 23 receptor	Homo sapiens	48-53
16658831-7	1974	Association of the lipase with the gly-oxysomal membrane was supported by the responses to detergents and to butanol.	Glycine	35-38	lipase	Ricinus communis	19-25
24498605-7	2013	We newly identified three mutations: two mutations in highly conserved Gly-Phe-Phe-Lys-Arg sequence in juxtamembrane region of alphaIIb, p.Gly991Cys and p.Phe993del, and one donor site mutation of intron 13 of ITGB3 leading to 40 amino acids deletion, p.(Asp621_Glu660del), in the membrane proximal beta-tail domain of beta3.	Glycine	71-74	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	319-324
26972276-4	2016	To establish efficient and reliable drug delivery to HER2-overexpressing cells, the authors of this study have developed anti-HER2 (ErbB2) peptide-liposomal formulations of doxorubicin (DOX) by an engineered breast tumor-targeting peptide ligand, AHNP, Anti-HER2/neu peptide, (FCDGFYACYADV) with three glycine amino acids as spacer before its original sequencing.	Glycine	302-321	erb-b2 receptor tyrosine kinase 2	Mus musculus	132-137
33296093-1	2021	Diffuse gliomas with H3F3A point mutations affecting histone H3.3 glycine position 34 are a distinct glioma subtype mostly occurring in the cerebral hemispheres of paediatric and young adult patients.	Glycine	66-73	H3.3 histone A	Homo sapiens	21-26
27065799-10	2016	While over a thousand genes showed altered expression levels, through pathway analysis we identified 14 top candidate genes belonging to five different canonical signaling pathways (signaling by calcium, TGF-beta, sonic hedgehog, Wnt, and p53-related apoptosis) that are likely to mediate the promotion of neurogenesis by glycine.	Glycine	322-329	tumor protein p53	Danio rerio	239-242
26692471-6	2016	In addition to synonymous mutations, the CPV-2c strains also contain a unique coding mutation in VP2 that leads to glycine at residue 5, instead of the highly conserved alanine at this position in all other CPV-2c strains sequenced to date.	Glycine	115-122	VP2	Canine parvovirus	97-100
26941605-10	2016	This is blocked by NMDAR antagonist 2-amino-5-phosphonopentanoic acid (AP5) and 7-chlorokynurenic acid (7-CK), a specific antagonist at the glycine site of NMDARs, demonstrating that D-serine effects are mediated through postsynaptic NMDARs.	Glycine	140-147	adaptor related protein complex 5 subunit beta 1	Homo sapiens	71-74
23805296-1	2013	NMDA receptors are activated after binding of the agonist glutamate to the NR2 subunit along with a co-agonist, either L-glycine or D-serine, to the NR1 subunit.	Glycine	119-128	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	149-152
23427147-3	2013	Another TARDBP ortholog, tardbpl, in zebrafish is shown to encode a Tardbp-like protein which is truncated compared with Tardbp itself and lacks part of the C-terminal glycine-rich domain (GRD).	Glycine	168-175	TAR DNA binding protein b	Danio rerio	8-14
23427147-3	2013	Another TARDBP ortholog, tardbpl, in zebrafish is shown to encode a Tardbp-like protein which is truncated compared with Tardbp itself and lacks part of the C-terminal glycine-rich domain (GRD).	Glycine	168-175	TAR DNA binding protein b	Danio rerio	68-74
23647259-7	2013	RESULTS: The range of IGF-1 released using the manufacturer"s pretreatment was between 23% and 56% of the amount released using the gly-gly pretreatment in different equine samples.	Glycine	132-135	insulin like growth factor 1	Equus caballus	22-27
33296093-1	2021	Diffuse gliomas with H3F3A point mutations affecting histone H3.3 glycine position 34 are a distinct glioma subtype mostly occurring in the cerebral hemispheres of paediatric and young adult patients.	Glycine	66-73	H3.3 histone A	Homo sapiens	53-65
26902152-3	2016	Here we reported the first methyltransferase, SET7/9 (KMT7), capable of methylating YY1 at two highly conserved lysine (K) residues, K173 and K411, located in two distinct domains, one in the central glycine-rich region and the other in the very carboxyl-terminus.	Glycine	200-207	SET domain containing 7, histone lysine methyltransferase	Homo sapiens	46-52
33959363-2	2021	The results showed that CyP6Q[6] forms a 1 : 2 inclusion complex with glycine, but 1 : 1 complexes with both leucine and lysine.	Glycine	70-77	peptidylprolyl isomerase G	Homo sapiens	24-27
26902152-3	2016	Here we reported the first methyltransferase, SET7/9 (KMT7), capable of methylating YY1 at two highly conserved lysine (K) residues, K173 and K411, located in two distinct domains, one in the central glycine-rich region and the other in the very carboxyl-terminus.	Glycine	200-207	SET domain containing 7, histone lysine methyltransferase	Homo sapiens	54-58
23647259-7	2013	RESULTS: The range of IGF-1 released using the manufacturer"s pretreatment was between 23% and 56% of the amount released using the gly-gly pretreatment in different equine samples.	Glycine	136-139	insulin like growth factor 1	Equus caballus	22-27
26632210-4	2016	In the present study, we investigated the effect of a highly selective GlyT1 inhibitor (named M22) on glycine transport kinetics using a radioactive substrate uptake assay and investigated the anti-seizure effects of M22 on the maximal electroshock seizure threshold (MEST) test and the timed intravenous (i.v.)	Glycine	102-109	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	71-76
33959363-3	2021	Whereas the carboxyl group of glycine can enter the interior of the cavity of CyP6Q[6], only the alkyl chains of leucine and lysine can enter this cavity.	Glycine	30-37	peptidylprolyl isomerase G	Homo sapiens	78-81
26881185-2	2016	Due to the presence of the recognition unit GGH (Gly-Gly-His), the probe C-GGH can coordinate with Cu(2+) and consequently display ON-OFF type fluorescence response.	Glycine	53-56	gamma-glutamyl hydrolase	Homo sapiens	75-78
33755704-10	2021	Notably, we have found a D614G (aspartic acid to glycine) mutation in spike protein of the sequences from the GH clade.	Glycine	49-56	gamma-glutamyl hydrolase	Homo sapiens	110-112
26818177-0	2016	Studies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility.	Glycine	80-86	poly(A) binding protein cytoplasmic 1	Homo sapiens	22-26
26818177-0	2016	Studies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility.	Glycine	80-86	poly(A) binding protein cytoplasmic 1	Homo sapiens	102-106
23514118-6	2013	The NH group of Gly, which as hydrogen bond donor competes with the NH group of Cys4 for the carbonyl oxygen atom of Cys1 as hydrogen bond acceptor, plays a relevant role for the structure and spectroscopic properties of the peptide.	Glycine	16-19	cystin 1	Homo sapiens	117-121
33746753-5	2021	The modulation of glycine-mediated inhibitory activity via IL-1beta may play a critical role in the perception of different levels of pain.	Glycine	18-25	interleukin 1 alpha	Homo sapiens	59-67
23295391-6	2013	), which is glycine-binding site inhibitor of N-methyl-d-aspartate receptor (NMDAR).	Glycine	12-19	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	46-75
26730381-3	2015	In the present study, the effects of fluoxetine, tianeptine, and milnacipran on the glycine-induced ion current by nystatin-perforated patch clamp and on the amplitude of field potential in the hippocampal CA1 region by multichannel extracellular recording, MED64, system, were studied.	Glycine	84-91	carbonic anhydrase 1	Rattus norvegicus	206-209
26730381-4	2015	In the present results, fluoxetine, tianeptine, and milnacipran reduced glycine-induced ion current in the hippocampal CA1 neurons in nystatin-perforated patch clamp method.	Glycine	72-79	carbonic anhydrase 1	Rattus norvegicus	119-122
23295391-6	2013	), which is glycine-binding site inhibitor of N-methyl-d-aspartate receptor (NMDAR).	Glycine	12-19	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	77-82
33539789-2	2021	At inhibitory synapses in the spinal cord, the main scaffold protein gephyrin assembles in dense molecule clusters that provide binding sites for glycine receptors (GlyRs).	Glycine	146-153	gephyrin	Homo sapiens	69-77
23339520-8	2013	In inhibition studies with glycyl-sarcosine (Gly-Sar, a typical substrate of PepT1), P(eff) of 7a (5.2-fold), 7b (2.0-fold), 9b (3.1-fold), and 9c (2.3-fold) had significantly reduced values (p &lt; 0.01).	Glycine	45-48	solute carrier family 15 member 1	Rattus norvegicus	77-82
33139925-5	2021	Multivalent and specific interactions between the dimeric E-domain of gephyrin and the glycine/GABAA receptor multimer are essential for the iPSD condensate formation.	Glycine	87-94	gephyrin	Homo sapiens	70-78
23486948-4	2013	We find that the plasma membrane transporter GlyT2 and the intracellular enzyme glutamate decarboxylase supply the majority of glycine and GABA, respectively.	Glycine	127-134	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	45-50
25604957-6	2015	Using cell culture models, we have defined the effects of R199W-DAO, and shown that it activates autophagy, leads to the formation of ubiquitinated protein aggregates and promotes apoptosis, all of which processes are attenuated by a D-serine/glycine site antagonist of the N-methyl D-aspartate receptor (NMDAR).	Glycine	243-250	D-amino acid oxidase	Homo sapiens	64-67
25604957-7	2015	These findings suggest that the toxic effects of R199W-DAO are at least in part mediated via the NMDAR involving the D-serine/glycine site and that an excitotoxic mechanism may contribute to disease pathogenesis.	Glycine	126-133	D-amino acid oxidase	Homo sapiens	55-58
26200505-1	2015	Glycine transporters (GlyT), GlyT1 and GlyT2, are responsible for the termination of glycine-mediated synaptic activity through removal of neurotransmitter from synaptic cleft.	Glycine	85-92	solute carrier family 6 member 5	Rattus norvegicus	39-44
33139925-8	2021	Phosphorylation of specific residues in the linker or binding of target proteins such as dynein light chain to the linker domain regulates gephyrin-mediated glycine/GABAA receptor clustering.	Glycine	157-164	gephyrin	Homo sapiens	139-147
33621197-0	2021	Resveratrol improves Gly-LDL-induced vascular endothelial cell apoptosis, inflammatory factor secretion and oxidative stress by regulating miR-142-3p and regulating SPRED2-mediated autophagy.	Glycine	21-24	sprouty related EVH1 domain containing 2	Homo sapiens	165-171
28955804-7	2016	Mutation of cysteine-32 but not cysteine-35 in the Trp-Cys32-Gly-Pro-Cys35 motif eliminated the binding of Trx1 with S-sulfhydrated proteins and abolished the S-desulfhydrating effect of Trx1.	Glycine	61-64	thioredoxin	Homo sapiens	107-111
28955804-7	2016	Mutation of cysteine-32 but not cysteine-35 in the Trp-Cys32-Gly-Pro-Cys35 motif eliminated the binding of Trx1 with S-sulfhydrated proteins and abolished the S-desulfhydrating effect of Trx1.	Glycine	61-64	thioredoxin	Homo sapiens	187-191
23421675-2	2013	We previously showed that the dramatic difference in glycine efficacies of alpha1 and alpha3 GlyRs is largely attributable to their nonconserved TM4 domains.	Glycine	53-60	glycine receptor alpha 1	Homo sapiens	75-98
23184331-6	2013	RESULTS: The minor allele codon 105 glycine (GGT) SNP (IDH1(105GGT) ) was identified in 98 of 952 patients (10.3%) and was not associated with the codon 132 (IDH1(132) ) mutation.	Glycine	36-43	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	55-59
33621197-7	2021	Inhibition of SPRED2 reversed the effects of resveratrol on Gly-LDL-induced HUVECs proliferation, apoptosis, inflammatory factor secretion and oxidative stress, and reversed the effects of resveratrol on Gly-LDL-induced HUVECs autophagy.	Glycine	60-63	sprouty related EVH1 domain containing 2	Homo sapiens	14-20
33369211-4	2021	Heterozygous carriers of frameshift/splicing variants in COL4A3/COL4A4 presented a higher risk of developing renal failure than those with missense variants in the glycine domains (p = 0.015).	Glycine	164-171	collagen type IV alpha 3 chain	Homo sapiens	57-63
26062933-1	2015	PURPOSE: The aim of this study was to investigate the biodistribution of 2-fluoropropionyl-labeled PEGylated dimeric arginine-glycine-aspartic acid (RGD) peptide (PEG3-E[c{RGDyk}]2) ((18)F-FPPRGD2) in cancer patients and to compare its uptake in malignant lesions with (18)F-FDG uptake.	Glycine	126-133	paternally expressed 3	Homo sapiens	163-167
33440850-5	2021	Cp deamidation occurs at two Asparagine-Glycine-Arginine (NGR)-motifs which, once deamidated to isoAspartate-Glycine-Arginine (isoDGR), bind integrins, a family of receptors mediating cell adhesion.	Glycine	40-47	ceruloplasmin	Homo sapiens	0-2
26386604-2	2015	An optimized lead from this series, 1j (rMCHR1 Ki=1.8 nM), demonstrated a 6.9% reduction in weight gain relative to vehicle in a rat model at 30 mg/kg after 4 days of once-daily oral treatment as a glycine prodrug.	Glycine	198-205	melanin-concentrating hormone receptor 1	Rattus norvegicus	40-46
22934986-1	2013	BACKGROUND: Stimulating the glycine(B)  binding site on the N-methyl-d-aspartate ionotropic glutamate receptor (NMDAR) has been proposed as a novel mechanism for modulating behavioral effects of ethanol (EtOH) that are mediated via the NMDAR, including acute intoxication.	Glycine	28-35	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	60-110
22934986-1	2013	BACKGROUND: Stimulating the glycine(B)  binding site on the N-methyl-d-aspartate ionotropic glutamate receptor (NMDAR) has been proposed as a novel mechanism for modulating behavioral effects of ethanol (EtOH) that are mediated via the NMDAR, including acute intoxication.	Glycine	28-35	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	112-117
22934986-1	2013	BACKGROUND: Stimulating the glycine(B)  binding site on the N-methyl-d-aspartate ionotropic glutamate receptor (NMDAR) has been proposed as a novel mechanism for modulating behavioral effects of ethanol (EtOH) that are mediated via the NMDAR, including acute intoxication.	Glycine	28-35	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	236-241
34043488-4	2022	To understand this ligation better, Met80 of horse cyt c has been mutated to Gly that is unable to bind to the heme iron.	Glycine	77-80	cytochrome c, somatic	Equus caballus	51-56
22975628-5	2013	A silk protein grafted with TiBP and fibronectin-derived arginine-glycine-aspartic acid (RGD) peptide was then prepared.	Glycine	66-73	fibronectin 1	Gallus gallus	37-48
26418248-7	2015	Interestingly, a 40-50% reduction in glycine uptake was detected in phorbol-ester stimulated cells expressing the WT-GlyT1, whereas no significant change was for the mutant protein, demonstrating that endocytosis participates in the reduction of uptake.	Glycine	37-44	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	117-122
33051383-4	2020	Here, we attempted to replicate data demonstrating the neurotransmitter glutamate, as well as NMDA and AP5, directly act at inhibitory glycine receptors as positive allosteric modulators.	Glycine	135-142	adaptor related protein complex 5 subunit beta 1	Homo sapiens	103-106
25620715-1	2015	Liver peroxisomal alanine:glyoxylate aminotransferase (AGT) (EC 2.6.1.44) catalyses the conversion of l-alanine and glyoxylate to pyruvate and glycine, a reaction that allows glyoxylate detoxification.	Glycine	143-150	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	18-53
25620715-1	2015	Liver peroxisomal alanine:glyoxylate aminotransferase (AGT) (EC 2.6.1.44) catalyses the conversion of l-alanine and glyoxylate to pyruvate and glycine, a reaction that allows glyoxylate detoxification.	Glycine	143-150	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	55-58
23841333-4	2013	The coordination of Cd2+ with those groups was supported by the application of auxiliary molecules (D-penicillamine, glycine, cysteine and glutamic acid dipeptides, mercaptosuccinic acid and N-acetyl-L-cysteine).	Glycine	117-124	CD2 molecule	Homo sapiens	20-23
32341465-8	2020	Farnesoid X receptor (FXR) inhibitor glycine-beta-muricholic acid or FXR knockdown reversed the downregulation of PepT1 expression by CDCA and GW4064 (another FXR agonist).	Glycine	37-44	nuclear receptor subfamily 1, group H, member 4	Rattus norvegicus	0-20
26013807-1	2015	L-kynurenine (Kyn) is a key element of tryptophan metabolism; it is enzymatically converted by kynurenine aminotransferase II (KAT II) to kynurenic acid (KYNA), which acts as an antagonist to the NMDA receptor-glycine site.	Glycine	210-217	aminoadipate aminotransferase	Mus musculus	95-125
26013807-1	2015	L-kynurenine (Kyn) is a key element of tryptophan metabolism; it is enzymatically converted by kynurenine aminotransferase II (KAT II) to kynurenic acid (KYNA), which acts as an antagonist to the NMDA receptor-glycine site.	Glycine	210-217	aminoadipate aminotransferase	Mus musculus	127-133
23121214-3	2013	At the rat extensor digitorum longus neuromuscular junction, activation of N-methyl-d-aspartate (NMDA) receptors by combined application of glutamate and glycine led to enhancement of nitric oxide (NO) production, resulting in partial AChE inhibition.	Glycine	154-161	acetylcholinesterase	Rattus norvegicus	235-239
31919571-3	2020	Substitution of position Q34 of neuropeptide Y to glycine (G34-NPY) results in unprecedented selectivity over all other YR subtypes.	Glycine	50-57	neuropeptide Y	Homo sapiens	63-66
23248076-9	2013	Furthermore, blastocyst development from oocytes that were vitrified with glycine was significantly higher compared to those vitrified without glycine (83.9 % vs. 76.5 % respectively; p&lt;0.05) and blastocysts derived from oocytes that were vitrified without glycine had significantly decreased levels of IGF2 and Glut3 compared to control blastocysts however those derived from oocytes vitrified with glycine had comparable levels of these genes compared to fresh controls.	Glycine	74-81	insulin-like growth factor 2	Mus musculus	306-310
32892440-6	2020	Furthermore, TRPV4 channels were able to enhance the frequency and amplitude of glycine receptor (GlyR)-mediated mIPSCs and inhibit the frequency of type A gamma-aminobutyric acid receptor (GABAA R)-mediated mIPSCs.	Glycine	80-87	transient receptor potential cation channel, subfamily V, member 4	Rattus norvegicus	13-18
23248076-9	2013	Furthermore, blastocyst development from oocytes that were vitrified with glycine was significantly higher compared to those vitrified without glycine (83.9 % vs. 76.5 % respectively; p&lt;0.05) and blastocysts derived from oocytes that were vitrified without glycine had significantly decreased levels of IGF2 and Glut3 compared to control blastocysts however those derived from oocytes vitrified with glycine had comparable levels of these genes compared to fresh controls.	Glycine	74-81	solute carrier family 2 (facilitated glucose transporter), member 3	Mus musculus	315-320
23443546-8	2013	In the C4 phosphoenolpyruvate carboxylase isoform, this arginine is replaced by glycine.	Glycine	80-87	phosphoenolpyruvate carboxykinase 1	Homo sapiens	10-41
32892440-7	2020	Upon intracellular administration or intravitreal injection of GSK101, TRPV4 channel activation reduced the release of presynaptic glycine and enhanced the function and expression of postsynaptic GlyRs; however, it inhibited presynaptic release of GABA, but did not affect postsynaptic GABAA Rs.	Glycine	131-138	transient receptor potential cation channel, subfamily V, member 4	Rattus norvegicus	71-76
32592234-15	2020	The sharp increase in hepatic concentrations of glycine, serine and putrescine, along with increased specific activities of MHMT, BHMT and SHMT from D1-7, suggests that methionine conservation (remethylation from homocysteine) and glycine/serine is critical for young chicks for organ growth, maturation, and development.	Glycine	231-238	dopamine receptor D1	Gallus gallus	149-153
33059700-10	2020	Moreover, the addition of Gly alleviated D-gal-mediated neuroinflammation by inhibiting gliosis via attenuation of astrocytosis (GFAP) and microgliosis (Iba-1) in addition to reducing the protein expression levels of various inflammatory cytokines (IL-1betaeta and TNFalpha).	Glycine	26-29	glial fibrillary acidic protein	Mus musculus	129-133
23126476-6	2012	To address this issue, we applied a stable-isotope (18)O-labeling method combined with nano-LC-MS/MS to examine the susceptibility of two Asn-Gly sites in beta2-microglobulin (beta2m) to the reaction.	Glycine	142-145	beta-2-microglobulin	Homo sapiens	155-174
33059700-10	2020	Moreover, the addition of Gly alleviated D-gal-mediated neuroinflammation by inhibiting gliosis via attenuation of astrocytosis (GFAP) and microgliosis (Iba-1) in addition to reducing the protein expression levels of various inflammatory cytokines (IL-1betaeta and TNFalpha).	Glycine	26-29	induction of brown adipocytes 1	Mus musculus	153-158
33059700-11	2020	Finally, the addition of Gly reversed D-gal-induced synaptic dysfunction by upregulating the expression of memory-related presynaptic protein markers (synaptophysin (SYP), syntaxin (Syn), and a postsynaptic density protein (PSD95)) and markedly improved behavioral measures of cognitive deficits in D-gal-treated mice.	Glycine	25-28	synaptophysin	Mus musculus	151-164
33059700-11	2020	Finally, the addition of Gly reversed D-gal-induced synaptic dysfunction by upregulating the expression of memory-related presynaptic protein markers (synaptophysin (SYP), syntaxin (Syn), and a postsynaptic density protein (PSD95)) and markedly improved behavioral measures of cognitive deficits in D-gal-treated mice.	Glycine	25-28	synaptophysin	Mus musculus	166-169
32389749-7	2020	Furthermore, we demonstrate that EU1180-438 produces robust inhibition of glycine-activated current responses mediated by native GluN1/GluN3A receptors in hippocampal CA1 pyramidal neurons.	Glycine	74-81	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	135-141
23216712-16	2012	CONCLUSION: Gly allele at codon 1057 in IRS-2 is correlated with an increased susceptibility to CAD in the Taiwanese population.	Glycine	12-15	insulin receptor substrate 2	Homo sapiens	40-45
32640336-6	2020	Both compounds increased the uterine ERalpha protein expression, with no differences at transcript level; and only Gly decreased PR mRNA expression.	Glycine	115-118	progesterone receptor	Rattus norvegicus	129-131
32578940-4	2020	Fibrochondrogenesis is also a COL11A1 related disorder, but here disease-associated variants are recessive and may be either null alleles or substitutions of glycine, and the condition is usually lethal in infancy.	Glycine	158-165	collagen type XI alpha 1 chain	Homo sapiens	30-37
23077177-3	2012	Earlier, we identified two distinct conserved motifs on the Na,K-beta(1) transmembrane domain that mediate protein-protein interactions: a glycine zipper motif involved in the cis homo-oligomerization of Na,K-beta(1) and a heptad repeat motif that is involved in the hetero-oligomeric interaction with Na,K-alpha(1).	Glycine	139-146	tubulin alpha 1b	Homo sapiens	305-315
32724448-8	2020	The results suggested that in individuals with the IRS1 Gly/Arg genotype, the odds of having gastric cancer was increased by 7.891-fold (95% CI: 3.251-19.154, P<0.001) and in individuals with the IRS1 Arg/Arg genotype, it was increased by 22.716-fold (95% CI: 6.311-81.761, P<0.001) compared with those with the IRS1 Gly/Gly genotype.	Glycine	56-59	insulin receptor substrate 1	Homo sapiens	51-55
23279345-0	2012	Two novel mutations of GARS in Korean families with distal hereditary motor neuropathy type V. Glycyl-tRNA synthetase (GARS), which encodes the enzyme responsible for charging tRNA(Gly) with glycine in both the cytoplasm and mitochondria, is implicated to Charcot-Marie-Tooth disease 2D (CMT2D) and distal hereditary motor neuropathy type V (dHMN-V).	Glycine	95-98	glycyl-tRNA synthetase 1	Homo sapiens	23-27
23279345-0	2012	Two novel mutations of GARS in Korean families with distal hereditary motor neuropathy type V. Glycyl-tRNA synthetase (GARS), which encodes the enzyme responsible for charging tRNA(Gly) with glycine in both the cytoplasm and mitochondria, is implicated to Charcot-Marie-Tooth disease 2D (CMT2D) and distal hereditary motor neuropathy type V (dHMN-V).	Glycine	95-98	glycyl-tRNA synthetase 1	Homo sapiens	119-123
23279345-0	2012	Two novel mutations of GARS in Korean families with distal hereditary motor neuropathy type V. Glycyl-tRNA synthetase (GARS), which encodes the enzyme responsible for charging tRNA(Gly) with glycine in both the cytoplasm and mitochondria, is implicated to Charcot-Marie-Tooth disease 2D (CMT2D) and distal hereditary motor neuropathy type V (dHMN-V).	Glycine	95-98	glycyl-tRNA synthetase 1	Homo sapiens	288-293
23279345-0	2012	Two novel mutations of GARS in Korean families with distal hereditary motor neuropathy type V. Glycyl-tRNA synthetase (GARS), which encodes the enzyme responsible for charging tRNA(Gly) with glycine in both the cytoplasm and mitochondria, is implicated to Charcot-Marie-Tooth disease 2D (CMT2D) and distal hereditary motor neuropathy type V (dHMN-V).	Glycine	191-198	glycyl-tRNA synthetase 1	Homo sapiens	23-27
32724448-8	2020	The results suggested that in individuals with the IRS1 Gly/Arg genotype, the odds of having gastric cancer was increased by 7.891-fold (95% CI: 3.251-19.154, P<0.001) and in individuals with the IRS1 Arg/Arg genotype, it was increased by 22.716-fold (95% CI: 6.311-81.761, P<0.001) compared with those with the IRS1 Gly/Gly genotype.	Glycine	56-59	insulin receptor substrate 1	Homo sapiens	196-200
23279345-0	2012	Two novel mutations of GARS in Korean families with distal hereditary motor neuropathy type V. Glycyl-tRNA synthetase (GARS), which encodes the enzyme responsible for charging tRNA(Gly) with glycine in both the cytoplasm and mitochondria, is implicated to Charcot-Marie-Tooth disease 2D (CMT2D) and distal hereditary motor neuropathy type V (dHMN-V).	Glycine	191-198	glycyl-tRNA synthetase 1	Homo sapiens	95-117
23279345-0	2012	Two novel mutations of GARS in Korean families with distal hereditary motor neuropathy type V. Glycyl-tRNA synthetase (GARS), which encodes the enzyme responsible for charging tRNA(Gly) with glycine in both the cytoplasm and mitochondria, is implicated to Charcot-Marie-Tooth disease 2D (CMT2D) and distal hereditary motor neuropathy type V (dHMN-V).	Glycine	191-198	glycyl-tRNA synthetase 1	Homo sapiens	119-123
32724448-8	2020	The results suggested that in individuals with the IRS1 Gly/Arg genotype, the odds of having gastric cancer was increased by 7.891-fold (95% CI: 3.251-19.154, P<0.001) and in individuals with the IRS1 Arg/Arg genotype, it was increased by 22.716-fold (95% CI: 6.311-81.761, P<0.001) compared with those with the IRS1 Gly/Gly genotype.	Glycine	56-59	insulin receptor substrate 1	Homo sapiens	196-200
23279345-0	2012	Two novel mutations of GARS in Korean families with distal hereditary motor neuropathy type V. Glycyl-tRNA synthetase (GARS), which encodes the enzyme responsible for charging tRNA(Gly) with glycine in both the cytoplasm and mitochondria, is implicated to Charcot-Marie-Tooth disease 2D (CMT2D) and distal hereditary motor neuropathy type V (dHMN-V).	Glycine	191-198	glycyl-tRNA synthetase 1	Homo sapiens	288-293
32724448-8	2020	The results suggested that in individuals with the IRS1 Gly/Arg genotype, the odds of having gastric cancer was increased by 7.891-fold (95% CI: 3.251-19.154, P<0.001) and in individuals with the IRS1 Arg/Arg genotype, it was increased by 22.716-fold (95% CI: 6.311-81.761, P<0.001) compared with those with the IRS1 Gly/Gly genotype.	Glycine	317-320	insulin receptor substrate 1	Homo sapiens	51-55
32724448-8	2020	The results suggested that in individuals with the IRS1 Gly/Arg genotype, the odds of having gastric cancer was increased by 7.891-fold (95% CI: 3.251-19.154, P<0.001) and in individuals with the IRS1 Arg/Arg genotype, it was increased by 22.716-fold (95% CI: 6.311-81.761, P<0.001) compared with those with the IRS1 Gly/Gly genotype.	Glycine	317-320	insulin receptor substrate 1	Homo sapiens	51-55
32724448-9	2020	Although the IRS2 Gly1057Asp genotype analysis suggested that subjects with the Asp/Asp genotype had a 2,311-fold increased odds of having gastric cancer compared to those with the Gly/Gly genotype, the result was not statistically significant (95% CI: 0.800-6.678, P=0.122).	Glycine	18-21	insulin receptor substrate 2	Homo sapiens	13-17
32812311-3	2020	Comparisons of experimental and theoretical IR spectra confirmed that both the charge and spin densities of [Y(G/A)Wpi   ]+ were delocalized initially at the tryptophan indolyl ring; subsequent formation of the final [Galpha   (G/A)W]+ structure gave the highest spin density at the alpha-carbon atom of the N-terminal glycine residue, with a proton solvated by the first amide oxygen atom.	Glycine	319-326	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	218-224
23041045-6	2012	As currents induced by the pressure application of glycine on LSO neurons were reduced by tetanic stimulation in P0-P3 heterozygous (+/cir) mice, LTD was thought to occur at postsynaptic sites.	Glycine	51-58	circling	Mus musculus	135-138
31356900-2	2020	At inhibitory synapses, the postsynaptic protein gephyrin self-assembles to form a scaffold that anchors glycine and GABAARs to the cytoskeleton, thus ensuring the accurate accumulation of postsynaptic receptors at the right place.	Glycine	105-112	gephyrin	Homo sapiens	49-57
22975845-2	2012	D-Serine is synthesized from L-serine by serine racemase (SR) and modulates NMDAR functions by acting as an agonist at the glycine-binding site.	Glycine	123-130	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	76-81
32556284-3	2020	The patient had a homozygous substitution of glycine by aspartate at amino acid residue 412 (Gly412Asp) in the thrombin-binding domain of the thrombomodulin gene (designated thrombomodulin-Nagasaki).	Glycine	45-52	thrombomodulin	Homo sapiens	142-156
22821889-3	2012	We have performed direct measurements of glycine flux by SN2 (Slc38a5; also known as SNAT5), executed extensive electrophysiological characterization as well as implemented ratiometric analyses to show that SN2 transport resembles SN1 in mechanism but differ in functional implications.	Glycine	41-48	solute carrier family 38, member 5	Rattus norvegicus	57-60
22821889-3	2012	We have performed direct measurements of glycine flux by SN2 (Slc38a5; also known as SNAT5), executed extensive electrophysiological characterization as well as implemented ratiometric analyses to show that SN2 transport resembles SN1 in mechanism but differ in functional implications.	Glycine	41-48	solute carrier family 38, member 5	Rattus norvegicus	62-69
22821889-3	2012	We have performed direct measurements of glycine flux by SN2 (Slc38a5; also known as SNAT5), executed extensive electrophysiological characterization as well as implemented ratiometric analyses to show that SN2 transport resembles SN1 in mechanism but differ in functional implications.	Glycine	41-48	solute carrier family 38, member 5	Rattus norvegicus	207-210
22821889-4	2012	We report that rat SN2 mediates electroneutral and bidirectional transport of glutamine and glycine at perisynaptic astroglial membranes.	Glycine	92-99	solute carrier family 38, member 5	Rattus norvegicus	19-22
22821889-5	2012	Sophisticated coupled and uncoupled movements of H(+) differentially associate with glutamine and glycine transport by SN2 and regulate pH(i) and the release mode of the transporter.	Glycine	98-105	solute carrier family 38, member 5	Rattus norvegicus	119-122
22796215-5	2012	The beneficial effect of glycine against oxygen and glucose deprivation (OGD) induced injury was also confirmed in SH-SY5Y cells as well as in primary cultured neurons, which was significantly dampened by knockdown of glycine receptor alpha1 (GlyR alpha1) with siRNA transfection or by preventing glycine binding with glycine receptor using a specific antibody against glycine receptor.	Glycine	25-32	glycine receptor alpha 1	Homo sapiens	218-254
32556284-3	2020	The patient had a homozygous substitution of glycine by aspartate at amino acid residue 412 (Gly412Asp) in the thrombin-binding domain of the thrombomodulin gene (designated thrombomodulin-Nagasaki).	Glycine	45-52	thrombomodulin	Homo sapiens	174-188
32217768-0	2020	Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine.	Glycine	61-68	potassium voltage-gated channel subfamily A member 1	Homo sapiens	18-23
22778260-1	2012	Gephyrin is a scaffold protein essential for the postsynaptic clustering of inhibitory glycine and different subtypes of GABA(A) receptors.	Glycine	87-94	gephyrin	Homo sapiens	0-8
32217768-6	2020	Here, we report that adjusting the number and positioning of fluorine atoms within the fluorophenyl ring of glycine derivatives produces isoform-selective KCNA1 channel openers that are inactive against KCNQ2/3 channels, or even KCNA2, the closest relative of KCNA1.	Glycine	108-115	potassium voltage-gated channel subfamily A member 1	Homo sapiens	155-160
32217768-6	2020	Here, we report that adjusting the number and positioning of fluorine atoms within the fluorophenyl ring of glycine derivatives produces isoform-selective KCNA1 channel openers that are inactive against KCNQ2/3 channels, or even KCNA2, the closest relative of KCNA1.	Glycine	108-115	potassium voltage-gated channel subfamily A member 1	Homo sapiens	260-265
22632602-1	2012	The proximal cavity mutant of myoglobin consists of a mutation of the proximal histidine to glycine (H93G), which permits exogenous ligands to bind to the heme iron.	Glycine	92-99	myoglobin	Homo sapiens	30-39
32426511-7	2020	Subsequently, substitution of R188 with glycine markedly enhances the affinity of the BHV-1-gD/nectin-1 interaction (by about fivefold).	Glycine	40-47	nectin cell adhesion molecule 1	Homo sapiens	95-103
32405339-7	2020	Our targeted metabolomics analysis showed distinct metabolomics profiles between IDC and adjacent tissue, where IDC displayed a comparative enrichment of metabolites involved in one-carbon metabolism (serine, glycine, threonine, and methionine) and a predicted increase in the activity of pathways that receive and donate carbon units (i.e., folate, methionine, and homocysteine).	Glycine	209-216	lamin A/C	Homo sapiens	112-115
21906419-3	2012	Glutamate evokes the release of D-serine from astrocytes and neurons, which then acts as a co-agonist and binds at the glycine site on the NR1 subunit of NMDA receptors.	Glycine	119-126	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	139-142
23554770-6	2012	Importantly, administration of glycine significantly inhibited apoptosis in post-ischemia-reperfusion myocardium, which was accompanied by suppression of phosphorylated p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase, as well as the Fas ligand.	Glycine	31-38	mitogen-activated protein kinase 8	Rattus norvegicus	210-235
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	0-7	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	256-259
32273387-3	2020	Here we report a specific interamacrine pathway from a small-field, glutamate-glycine dual-transmitter amacrine cell (vGluT3) to a wide-field polyaxonal amacrine cell (PAS4/5).	Glycine	78-85	solute carrier family 17 member 8	Homo sapiens	118-124
31967407-6	2020	In particular two proteins, the cellular mRNA deadenylase CCR4 (carbon catabolite repressor 4)-NOT (Negative on TATA) complex subunit 2/9 (CNOT2/9) and the serine hydroxymethyltransferase that catalyzes the reversible interconversions of serine and glycine (SHMT1) were found at dramatic low levels in the thymic epithelia of more malignant subtype, thymic squamous cell carcinoma (TSCC).	Glycine	249-256	serine hydroxymethyltransferase 1	Homo sapiens	258-263
22747601-5	2012	RESULTS: To investigate the structural and functional consequences of these divergent clusters, we report the X-ray crystal structures of S100A15 and S100A7D24G, a hybrid variant where the zinc ligand Asp24 of S100A7 has been substituted with the glycine of S100A15, to 1.7 A and 1.6 A resolution, respectively.	Glycine	247-254	S100 calcium binding protein A7A	Homo sapiens	138-145
31639107-3	2020	We created 2 mouse models of vEDS that carry heterozygous mutations in Col3a1 that encode glycine substitutions analogous to those found in patients, and we showed that signaling abnormalities in the PLC/IP3/PKC/ERK pathway (phospholipase C/inositol 1,4,5-triphosphate/protein kinase C/extracellular signal-regulated kinase) are major mediators of vascular pathology.	Glycine	90-97	collagen, type III, alpha 1	Mus musculus	71-77
22492235-8	2012	We also showed that the conserved glycine residues at positions 180 and 277 of SLC35C1 have significant impacts on AAL binding to CHO-gmt5 cells, suggesting that these conserved glycine residues are required for the transport activity of Slc35 proteins.	Glycine	34-41	GDP-fucose transporter 1	Cricetulus griseus	79-86
22492235-8	2012	We also showed that the conserved glycine residues at positions 180 and 277 of SLC35C1 have significant impacts on AAL binding to CHO-gmt5 cells, suggesting that these conserved glycine residues are required for the transport activity of Slc35 proteins.	Glycine	178-185	GDP-fucose transporter 1	Cricetulus griseus	79-86
31808207-8	2020	A missense COL4A1 mutation involving glycine residue was detected in the patient.	Glycine	37-44	collagen type IV alpha 1 chain	Homo sapiens	11-17
31610215-5	2020	Moreover, we found that glycine and D-cycloserine treatment rescued the aggressive behavior of chd7 heterozygous zebrafish mutants, indicating that the excitation and inhibition balance might be disrupted in the brains of chd7 heterozygous zebrafish mutants.	Glycine	24-31	chromodomain helicase DNA binding protein 7	Danio rerio	95-99
22773562-3	2012	Chloramines of proline, arginine, and glycine caused significant damage to PCNA in cells.	Glycine	38-45	proliferating cell nuclear antigen	Homo sapiens	75-79
31610215-5	2020	Moreover, we found that glycine and D-cycloserine treatment rescued the aggressive behavior of chd7 heterozygous zebrafish mutants, indicating that the excitation and inhibition balance might be disrupted in the brains of chd7 heterozygous zebrafish mutants.	Glycine	24-31	chromodomain helicase DNA binding protein 7	Danio rerio	222-226
22579572-13	2012	The GABA-evoked [(3)H]glycine efflux could be prevented by niflumic acid or NPPB indicating that the evoked release occurred essentially by permeation through anion channels.	Glycine	22-29	natriuretic peptide type B	Mus musculus	76-80
22579572-14	2012	In conclusion, GABA uptake into GlyT2-bearing cerebellar nerve endings triggered glycine release which occurred essentially by permeation through Ca(2+)-dependent anion channels.	Glycine	81-88	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	32-37
26081118-10	2015	At 6 months, TLR4 299Asp/Gly (P=0.02) and 399Ile/Thr (P=0.023) polymorphisms were significantly associated with the calcification or persistence of SCG.	Glycine	25-28	toll like receptor 4	Homo sapiens	13-17
31610215-6	2020	Further analysis showed that the expression of glycine transporters was dramatically increased in the brains of chd7 heterozygous zebrafish mutants.	Glycine	47-54	chromodomain helicase DNA binding protein 7	Danio rerio	112-116
31610215-7	2020	Treatment with an inhibitor of glycine transporter 1, sarcosine, partially rescued the aggressive-like behavior of chd7 heterozygous zebrafish mutants.	Glycine	31-38	chromodomain helicase DNA binding protein 7	Danio rerio	115-119
33148838-5	2020	RESULTS: Results: It has been established that individuals with mutant genotypes Arg/Gln of TLR-2, Leu/Phe, Phe/Phe of TLR-3, Asp/Gly of TLR-4 genes have a vaccinal response to administering anti-influenza vaccine at the level of subjects with normal distribution of TLR alleles, as evidenced by the growth in dynamics of mean geometric titers of antibodies to vaccine strains, the level of seroprotection and seroconversion.	Glycine	130-133	toll like receptor 4	Homo sapiens	137-142
26349957-4	2015	Molecular genetics showed a germ-line mutation of the MLH1 gene, 1858 G&gt;T(E620X), with substitution of glycine with a stop codon at position 620.	Glycine	106-113	mutL homolog 1	Homo sapiens	54-58
26022122-8	2015	The structure and structure-based mutational analyses suggest that either the last five residues at the extreme C-terminus of Cdc14p (residues 547-551; Gly-Ser-Ile-Lys-Lys) or adjacent residues with similar sequence (residues 540-544; Gly-Gly-Ile-Arg-Lys) can bind to the NLS-binding site of Kap121p, with two residues (Ile in the middle and Lys at the end of the five residues) of Cdc14p making key contributions to the binding specificity.	Glycine	152-155	phosphoprotein phosphatase CDC14	Saccharomyces cerevisiae S288C	126-132
22316404-9	2012	Besides being markedly lower than that in AQP9(+/+)  mice, the liver P(gly)  of the AQP9 null mice did not increase during fasting.	Glycine	71-74	aquaporin 9	Mus musculus	84-88
22521586-11	2012	Moreover, they highlight the glycine modulatory site (GMS) of the NMDAR as a potential target for therapeutic intervention in diseases characterized by synaptic deficits, like schizophrenia.	Glycine	29-36	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	66-71
31877957-10	2019	In addition, CTR1 protein expression level decreased after 120 muM CuSO4 and Cu-Gly exposure.	Glycine	77-83	solute carrier family 31 member 1	Sus scrofa	13-17
22453920-6	2012	The role of the terminal glycine of MOCS2A and URM1 was examined for the interaction and the cellular localization with MOCS3.	Glycine	25-32	molybdenum cofactor synthesis 3	Homo sapiens	120-125
22453920-7	2012	Deletion of the C-terminal glycine of either MOCS2A or URM1 resulted in a loss of interaction with MOCS3.	Glycine	27-34	molybdenum cofactor synthesis 3	Homo sapiens	99-104
22453920-9	2012	The cellular localization results showed that extension of the C terminus with an additional glycine of MOCS2A and URM1 altered the localization of MOCS3 from the cytosol to the nucleus.	Glycine	93-100	molybdenum cofactor synthesis 3	Homo sapiens	148-153
26101830-2	2015	The glycine concentration in the synaptic cleft is controlled by the glycine transporters GlyT1 and GlyT2.	Glycine	4-11	solute carrier family 6 member 5	Rattus norvegicus	100-105
31704028-5	2019	When binding to its agonist glycine or D-serine, GluD1 elicits non-ionotropic postsynaptic signaling involving the guanine nucleotide exchange factor ARHGEF12 and the regulatory subunit of protein phosphatase 1 PPP1R12A.	Glycine	28-35	glutamate dehydrogenase 1	Homo sapiens	49-54
26015579-7	2015	We demonstrate than an N-terminal, arginine/glycine rich, intrinsically disordered protein (IDP) domain of LAF-1 is necessary and sufficient for both phase separation and RNA-protein interactions.	Glycine	44-51	ATP-dependent RNA helicase laf-1	Caenorhabditis elegans	107-112
22265310-2	2012	The highest extracellular proteolytic activity was detected for 8 strains with values ranging between 2.086 and 4.685 mM Gly L-1 of milk.	Glycine	121-124	L1 cell adhesion molecule	Mus musculus	125-128
31147751-6	2019	However, SBP was directly related to certain microbial genera and glycine-conjugated metabolites in CKD rats.	Glycine	66-73	spermine binding protein	Rattus norvegicus	9-12
25735223-3	2015	The purpose of this study was to evaluate SPECT imaging of (99m)Tc-Gly-(D)Ala-Gly-Gly-Z(HER2:342) ((99m)Tc-peptide-Z(HER2:342)) for monitoring therapeutic response to trastuzumab in nude mice bearing HER2-positive SKOV-3 xenografts.	Glycine	67-70	erb-b2 receptor tyrosine kinase 2	Mus musculus	88-92
25735223-3	2015	The purpose of this study was to evaluate SPECT imaging of (99m)Tc-Gly-(D)Ala-Gly-Gly-Z(HER2:342) ((99m)Tc-peptide-Z(HER2:342)) for monitoring therapeutic response to trastuzumab in nude mice bearing HER2-positive SKOV-3 xenografts.	Glycine	67-70	erb-b2 receptor tyrosine kinase 2	Mus musculus	117-121
25735223-3	2015	The purpose of this study was to evaluate SPECT imaging of (99m)Tc-Gly-(D)Ala-Gly-Gly-Z(HER2:342) ((99m)Tc-peptide-Z(HER2:342)) for monitoring therapeutic response to trastuzumab in nude mice bearing HER2-positive SKOV-3 xenografts.	Glycine	67-70	erb-b2 receptor tyrosine kinase 2	Mus musculus	117-121
22342492-2	2012	Disruption of glycine-reuptake near excitatory synapses is expected to enhance NMDAR function by increasing glycine-B site occupancy.	Glycine	14-21	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	79-84
31444411-3	2019	Here, we report that the gene encoding glycine decarboxylase (GLDC), which catalyzes the first and rate-limiting step in glycine breakdown with the production of the one-carbon unit 5,10-methylene-tetrahydrofolate, is a direct transcriptional target of MYCN.	Glycine	39-46	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	253-257
31585995-7	2019	2-Amino-3-ketobutyrate coenzyme A (CoA) ligase (KBL) catalyzes the cleavage of l-2-amino-acetoacetate, the product of TDH, into glycine and acetyl-CoA in the presence of CoA.	Glycine	128-135	threonine 3-dehydrogenase	Bacillus subtilis subsp. subtilis str. 168	118-121
22422993-3	2012	Drugs patterned on the integrin ligand sequence Arg-Gly-Asp have a basic moiety that binds the alpha(IIb) subunit and a carboxyl group that coordinates the MIDAS Mg(2+) in the beta(3) subunits.	Glycine	52-55	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	176-183
25955356-3	2015	The resulting splice insert in the receptor for the inhibitory neurotransmitter glycine (GlyR) conveys synaptic receptor clustering and specific association with a particular synaptic plasticity-related splice variant of the postsynaptic scaffold protein gephyrin.	Glycine	80-87	gephyrin	Homo sapiens	255-263
25858298-0	2015	Fortuitous description of haemoglobin A2" [delta16 (A13) Gly Arg (GGC CGC)] in a Tunisian family: study of the molecular defect and its origin.	Glycine	57-60	immunoglobulin kappa variable 2D-18 (pseudogene)	Homo sapiens	52-55
25858298-3	2015	HbA2" [delta16 (A13) Gly Arg (GGC CGC)] is a delta-chain variant that has been identified in several populations of African origin.	Glycine	21-24	immunoglobulin kappa variable 2D-18 (pseudogene)	Homo sapiens	16-19
22371697-3	2012	GCAPs consist of four EF-hand domains and contain N-terminal fatty acylated glycine, which in GCAP1 is required for the normal activation of RetGC.	Glycine	76-83	guanylate cyclase 2D, retinal	Homo sapiens	141-146
31697492-5	2019	With glycine as a competitive ligand, the affinity of Cu2+ for full-length alphaSyn is determined to have a conditional dissociation constant, at pH 7.4, of 0.1 nM.	Glycine	5-12	synuclein alpha	Homo sapiens	75-83
22233892-0	2012	Activation of glycine site and GluN2B subunit of NMDA receptors is necessary for ERK/CREB signaling cascade in rostral anterior cingulate cortex in rats: implications for affective pain.	Glycine	14-21	cAMP responsive element binding protein 1	Rattus norvegicus	85-89
22233892-9	2012	CONCLUSION: Either the glycine site or the GluN2B subunit of NMDARs participates in the phosphorylation of ERK and CREB induced by bath application of NMDA in brain slices or hindpaw injection of 5% formalin in rats, and these might be fundamental molecular mechanisms underlying pain affect.	Glycine	23-30	cAMP responsive element binding protein 1	Rattus norvegicus	115-119
25667086-2	2015	Cav-2 is myristoylated at Gly-2 and palmitoylated at Cys-109, Cys-122, and Cys-145.	Glycine	26-29	caveolin 2	Homo sapiens	0-5
31494500-7	2019	Whereas the activation gate region of the voltage-gated K+ channel family is spanned, primarily, by large and b-branched hydrophobic residues, the leak K2P channel activation gate is spanned mainly by glycines and other hydrophilic residues.	Glycine	201-209	keratin 76	Homo sapiens	152-155
25882190-1	2015	Gephyrin is a central element that anchors, clusters and stabilizes glycine and gamma-aminobutyric acid type A receptors at inhibitory synapses of the mammalian brain.	Glycine	68-75	gephyrin	Homo sapiens	0-8
22848402-6	2012	Using a proteomic analysis, we determined that the cleavage occurs in a conserved motif of the N-terminal nucleotide binding site, between Ile-126 and Gly-127 in Hsp90beta, and between Ile-131 and Gly-132 in Hsp90alpha.	Glycine	151-154	heat shock protein 90 alpha family class B member 1	Homo sapiens	162-171
22848402-6	2012	Using a proteomic analysis, we determined that the cleavage occurs in a conserved motif of the N-terminal nucleotide binding site, between Ile-126 and Gly-127 in Hsp90beta, and between Ile-131 and Gly-132 in Hsp90alpha.	Glycine	151-154	heat shock protein 90 alpha family class A member 1	Homo sapiens	208-218
22848402-6	2012	Using a proteomic analysis, we determined that the cleavage occurs in a conserved motif of the N-terminal nucleotide binding site, between Ile-126 and Gly-127 in Hsp90beta, and between Ile-131 and Gly-132 in Hsp90alpha.	Glycine	197-200	heat shock protein 90 alpha family class A member 1	Homo sapiens	208-218
25817250-5	2015	In conditions involving down regulated GSH homeostasis, GGC serves asa crucialrate-limiting substrate for GSH synthetase, the main enzyme responsible for condensing glycine with GGC to form the final thiol tripeptide, GSH.	Glycine	165-172	glutathione synthetase	Homo sapiens	106-120
31548413-6	2019	We also found that the synaptic NMDAR activation in adult SR-knockout (KO) mice requires Phgdh-derived glycine, despite the sharp decline in the postnatal glycine levels as a result of the emergence of the glycine cleavage system.	Glycine	103-110	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	32-37
22646841-13	2012	CONCLUSION: The results of this study suggest that there is a positive correlation between some serum amino acid values, especially serine, glycine, isoleucine, and phenylalanine, and the high concentrations of SAA in chickens with amyloid arthropathy.	Glycine	140-147	serum amyloid A	Gallus gallus	211-214
31548413-10	2019	Our observations suggest that glycine is a multifaceted regulator of d-serine metabolism and implicate both d-serine and glycine in mediating NMDAR synaptic activation at the mature hippocampus through a Phgdh-dependent shuttle mechanism.	Glycine	30-37	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	142-147
31548413-10	2019	Our observations suggest that glycine is a multifaceted regulator of d-serine metabolism and implicate both d-serine and glycine in mediating NMDAR synaptic activation at the mature hippocampus through a Phgdh-dependent shuttle mechanism.	Glycine	121-128	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	142-147
22152680-3	2011	We identified the homozygous mutation c.746G&gt;A (p.Arg249His) in LIAS in an individual with neonatal-onset epilepsy, muscular hypotonia, lactic acidosis, and elevated glycine concentration in plasma and urine.	Glycine	169-176	lipoic acid synthetase	Homo sapiens	67-71
25579325-2	2015	The glycine transporter-2 (GlyT2) is localized at presynaptic terminals of glycinergic neurons and eliminates glycine from the synaptic cleft to terminate glycinergic transmission.	Glycine	4-11	solute carrier family 6 member 5	Rattus norvegicus	27-32
31439631-1	2019	GIGYF (Grb10-interacting GYF [glycine-tyrosine-phenylalanine domain]) proteins coordinate with 4EHP (eIF4E [eukaryotic initiation factor 4E] homologous protein), the DEAD (Asp-Glu-Ala-Asp)-box helicase Me31B/DDX6, and mRNA-binding proteins to elicit transcript-specific repression.	Glycine	30-37	growth factor receptor bound protein 10	Homo sapiens	7-12
25783028-6	2015	NEDD8 is translated as a precursor protein and proteolytic processing exposes a C-terminal glycine required for NEDD8 conjugation.	Glycine	91-98	related to ubiquitin 1	Arabidopsis thaliana	0-5
25783028-6	2015	NEDD8 is translated as a precursor protein and proteolytic processing exposes a C-terminal glycine required for NEDD8 conjugation.	Glycine	91-98	related to ubiquitin 1	Arabidopsis thaliana	112-117
31439631-1	2019	GIGYF (Grb10-interacting GYF [glycine-tyrosine-phenylalanine domain]) proteins coordinate with 4EHP (eIF4E [eukaryotic initiation factor 4E] homologous protein), the DEAD (Asp-Glu-Ala-Asp)-box helicase Me31B/DDX6, and mRNA-binding proteins to elicit transcript-specific repression.	Glycine	30-37	eukaryotic translation initiation factor 4E family member 2	Homo sapiens	95-99
30837697-2	2019	Vascular EDS (vEDS) is caused by pathogenic variants in COL3A1, most frequently glycine substitutions.	Glycine	80-87	collagen type III alpha 1 chain	Homo sapiens	56-62
25367099-1	2015	Costello syndrome (CS) is a rare genetic disorder caused, in the majority of cases, by germline missense HRAS mutations affecting Gly(12) promoting enhanced signaling through the MAPK and PI3K-AKT signaling cascades.	Glycine	130-133	HRas proto-oncogene, GTPase	Homo sapiens	105-109
32003208-11	2019	At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p <0.01), Gly/ Arg - 9.9% (p <0.01) and Arg/Arg - 3.3% (p <0.05).	Glycine	95-98	insulin receptor substrate 1	Homo sapiens	74-79
25269793-4	2014	Our results show that the permeation activity of TD1-hEGF, a fusion protein composed of human epidermal growth factor (hEGF) and the TD1 sequence connected with a glycine-serine linker (GGGGS), can be inhibited by the energy inhibitor, rotenone or oligomycin.	Glycine	163-170	epidermal growth factor	Homo sapiens	94-117
22045124-9	2011	A nonsynonymous single nucleotide polymorphism in the hSIK1 gene exon 3 (C T, rs3746951) results in the amino acid change (15)Gly Ser in the SIK1 protein.	Glycine	126-129	salt inducible kinase 1	Homo sapiens	54-59
22045124-9	2011	A nonsynonymous single nucleotide polymorphism in the hSIK1 gene exon 3 (C T, rs3746951) results in the amino acid change (15)Gly Ser in the SIK1 protein.	Glycine	126-129	salt-inducible kinase 1	Rattus norvegicus	55-59
32003208-11	2019	At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p <0.01), Gly/ Arg - 9.9% (p <0.01) and Arg/Arg - 3.3% (p <0.05).	Glycine	95-98	insulin receptor substrate 1	Homo sapiens	74-79
32003208-12	2019	Hypertensive patients with Arg/Arg and Gly/Arg genotypes had significantly higher HOMA-IR (p <0.01), glucose, insulin and triglycerides levels (p <0.05), than in Gly/Gly genotype.	Glycine	162-165	ABL proto-oncogene 2, non-receptor tyrosine kinase	Homo sapiens	27-30
32003208-12	2019	Hypertensive patients with Arg/Arg and Gly/Arg genotypes had significantly higher HOMA-IR (p <0.01), glucose, insulin and triglycerides levels (p <0.05), than in Gly/Gly genotype.	Glycine	162-165	ABL proto-oncogene 2, non-receptor tyrosine kinase	Homo sapiens	27-30
25168305-5	2014	In tissue-culture-expressed GlyT1 at least two of these mutations altered the sensitivity of GlyT1 surface expression and glycine uptake to calmodulin antagonists.	Glycine	122-129	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	28-33
31088832-3	2019	Here we report that neuroblastoma cells with MYCN amplification show increased transcriptional activation of the serine-glycine-one-carbon (SGOC) biosynthetic pathway and an increased dependence on this pathway for supplying glucose-derived carbon for serine and glycine synthesis.	Glycine	120-127	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	45-49
24996626-4	2014	ATG4 processes ATG8 precursor to expose its C-terminal glycine for phosphatidyl ethanolamine (PE) lipidation.	Glycine	55-62	autophagy-related protein 8A	Triticum aestivum	15-19
24996626-8	2014	GFP fusion proteins of ATG8s, especially of ATG8s with innate C-terminal-exposed glycines, localized to punctate autophagic membranes.	Glycine	81-89	autophagy-related protein 8A	Triticum aestivum	23-27
22001920-1	2011	Ubiquitin (Ub) carboxyl-terminal hydrolase L1 (UCH-L1) has dual functions, such as hydrolase activity on the chemical bonds formed by the C-terminal Gly of Ub and dimerization-dependent ubiquitin ligase activity.	Glycine	149-152	ubiquitin C-terminal hydrolase L1	Homo sapiens	43-45
22001920-1	2011	Ubiquitin (Ub) carboxyl-terminal hydrolase L1 (UCH-L1) has dual functions, such as hydrolase activity on the chemical bonds formed by the C-terminal Gly of Ub and dimerization-dependent ubiquitin ligase activity.	Glycine	149-152	ubiquitin C-terminal hydrolase L1	Homo sapiens	47-53
24996626-8	2014	GFP fusion proteins of ATG8s, especially of ATG8s with innate C-terminal-exposed glycines, localized to punctate autophagic membranes.	Glycine	81-89	autophagy-related protein 8A	Triticum aestivum	44-48
31315253-4	2019	Additionally, we combined WIV and N3 with a DNA-encoded TLR5 agonist secreted flagellin (pFliC(-gly)) as an adjuvant, as this adjuvant has previously been shown to improve the effectiveness of plasmid-encoded DNA antigens.	Glycine	96-99	toll like receptor 5	Homo sapiens	56-60
25009140-8	2014	Pro 5 and Gly 6 adopt a type II tight turn and Lys 2"s zeta-NH3(+) is positioned to form a favorable cation-pi interaction with Trp 4"s indole ring.	Glycine	10-13	aminoadipate-semialdehyde dehydrogenase	Homo sapiens	47-52
22004682-6	2011	RESULTS: Down regulation of uPA/uPAR, either singly or simultaneously, in U251 MG and tumor xenografts inhibited the cleavage of the Notch receptor between the Gly 1743 and Val 1744 positions, thereby suggesting inhibition of activated cytosolic fragment-related Notch gene transcription.	Glycine	160-163	plasminogen activator, urokinase receptor	Homo sapiens	32-36
23888104-2	2011	These studies were conducted to determine hPHT1-mediated, H+-dependent uptake kinetics of histidine, carnosine, Gly-Sar and valacyclovir in stably transfected hPHT1-COS-7 cells comparative to kinetics determined in an empty vector (Mock) stably transfected cell line.	Glycine	112-115	solute carrier family 15 member 4	Homo sapiens	42-47
23888104-3	2011	The results suggest that Gly-Sar appears to be a substrate for PHT1 based on efflux from the stably transfected hPHT1 COS-7 cells.	Glycine	25-28	solute carrier family 15 member 4	Homo sapiens	63-67
23888104-3	2011	The results suggest that Gly-Sar appears to be a substrate for PHT1 based on efflux from the stably transfected hPHT1 COS-7 cells.	Glycine	25-28	solute carrier family 15 member 4	Homo sapiens	112-117
24690400-7	2014	For Asp299Gly polymorphism of the TLR4 gene we found that there were no control individuals who were homozygous carriers of the Gly/Gly genotype, and the risk for SSPE increased at approximately 4.7 fold for the heterozygous carriers of the Asp/Gly genotype (OR 4.727, 95%-CI 1.192-18.742; P=0.01), when compared to healthy controls.	Glycine	10-13	toll like receptor 4	Homo sapiens	34-38
24690400-7	2014	For Asp299Gly polymorphism of the TLR4 gene we found that there were no control individuals who were homozygous carriers of the Gly/Gly genotype, and the risk for SSPE increased at approximately 4.7 fold for the heterozygous carriers of the Asp/Gly genotype (OR 4.727, 95%-CI 1.192-18.742; P=0.01), when compared to healthy controls.	Glycine	128-131	toll like receptor 4	Homo sapiens	34-38
30759996-9	2019	In contexts of siRNA knockdown and naturally occurring human genetic mutation, cellular BOLA3 deficiency downregulated the glycine cleavage system protein H, thus bolstering intracellular glycine content.	Glycine	123-130	bolA family member 3	Homo sapiens	88-93
24690400-7	2014	For Asp299Gly polymorphism of the TLR4 gene we found that there were no control individuals who were homozygous carriers of the Gly/Gly genotype, and the risk for SSPE increased at approximately 4.7 fold for the heterozygous carriers of the Asp/Gly genotype (OR 4.727, 95%-CI 1.192-18.742; P=0.01), when compared to healthy controls.	Glycine	128-131	toll like receptor 4	Homo sapiens	34-38
30759996-10	2019	In the setting of these alterations of oxidative metabolism and glycine levels, BOLA3 deficiency increased endothelial proliferation, survival, and vasoconstriction while decreasing angiogenic potential.	Glycine	64-71	bolA family member 3	Homo sapiens	80-85
30759996-12	2019	Notably, the therapeutic effects of BOLA3 expression were reversed by exogenous glycine supplementation.	Glycine	80-87	bolA family member 3	Homo sapiens	36-41
30759996-13	2019	CONCLUSIONS: BOLA3 acts as a crucial lynchpin connecting Fe-S-dependent oxidative respiration and glycine homeostasis with endothelial metabolic reprogramming critical to PH pathogenesis.	Glycine	98-105	bolA family member 3	Homo sapiens	13-18
30746902-2	2019	Our results showed that gly-HDL caused macrophage apoptosis with concomitant activation of ER stress pathway, including nuclear translocation of activating transcription factor 6, phosphorylation of protein kinase-like ER kinase (PERK) and eukaryotic translation initiation factor 2alpha, and CHOP up-regulation, which were inhibited by 4-phenylbutyric acid (PBA, an ER stress inhibitor) and the gene silencing of PERK and CHOP.	Glycine	24-27	activating transcription factor 6	Homo sapiens	145-178
24991000-3	2014	Inspection of the CA sequences of lentiviruses reveals that several species of simian immunodeficiency viruses (SIVs) have lost the glycine-proline motif in the helix 4-5 loop important for CypA binding; instead, the helix 4-5 loop in these SIVs exhibits an increase in the number of glutamine residues.	Glycine	132-139	peptidylprolyl isomerase A	Homo sapiens	190-194
21798518-0	2011	RGS2 and RGS4 modulate melatonin-induced potentiation of glycine currents in rat retinal ganglion cells.	Glycine	57-64	regulator of G-protein signaling 2	Rattus norvegicus	0-4
30746902-2	2019	Our results showed that gly-HDL caused macrophage apoptosis with concomitant activation of ER stress pathway, including nuclear translocation of activating transcription factor 6, phosphorylation of protein kinase-like ER kinase (PERK) and eukaryotic translation initiation factor 2alpha, and CHOP up-regulation, which were inhibited by 4-phenylbutyric acid (PBA, an ER stress inhibitor) and the gene silencing of PERK and CHOP.	Glycine	24-27	eukaryotic translation initiation factor 2 alpha kinase 3	Homo sapiens	199-228
21798518-0	2011	RGS2 and RGS4 modulate melatonin-induced potentiation of glycine currents in rat retinal ganglion cells.	Glycine	57-64	regulator of G-protein signaling 4	Rattus norvegicus	9-13
30746902-2	2019	Our results showed that gly-HDL caused macrophage apoptosis with concomitant activation of ER stress pathway, including nuclear translocation of activating transcription factor 6, phosphorylation of protein kinase-like ER kinase (PERK) and eukaryotic translation initiation factor 2alpha, and CHOP up-regulation, which were inhibited by 4-phenylbutyric acid (PBA, an ER stress inhibitor) and the gene silencing of PERK and CHOP.	Glycine	24-27	eukaryotic translation initiation factor 2 alpha kinase 3	Homo sapiens	230-234
21798518-2	2011	In the present study, we investigated the possible impact of RGS2 and RGS4 on modulation of glycine currents of rat retinal ganglion cells (RGCs) mediated by the G(i/o)-coupled melatonin MT(2) receptor, using immunohistochemistry, Western blot analysis and whole-cell patch-clamp techniques.	Glycine	92-99	regulator of G-protein signaling 2	Rattus norvegicus	61-65
30746902-2	2019	Our results showed that gly-HDL caused macrophage apoptosis with concomitant activation of ER stress pathway, including nuclear translocation of activating transcription factor 6, phosphorylation of protein kinase-like ER kinase (PERK) and eukaryotic translation initiation factor 2alpha, and CHOP up-regulation, which were inhibited by 4-phenylbutyric acid (PBA, an ER stress inhibitor) and the gene silencing of PERK and CHOP.	Glycine	24-27	eukaryotic translation initiation factor 2 alpha kinase 3	Homo sapiens	414-418
21798518-2	2011	In the present study, we investigated the possible impact of RGS2 and RGS4 on modulation of glycine currents of rat retinal ganglion cells (RGCs) mediated by the G(i/o)-coupled melatonin MT(2) receptor, using immunohistochemistry, Western blot analysis and whole-cell patch-clamp techniques.	Glycine	92-99	regulator of G-protein signaling 4	Rattus norvegicus	70-74
21798518-8	2011	Intracellular dialysis of RGCs with the antibody against RGS2/RGS4 to block RGS2/RGS4 function gradually increased glycine current amplitudes of these cells.	Glycine	115-122	regulator of G-protein signaling 2	Rattus norvegicus	57-61
30746902-4	2019	Gly-HDL induced macrophage autophagy as assessed by up-regulation of beclin-1, autophagy-related gene 5 and microtubule-associated protein one light chain 3-II, which were depressed by PBA and PERK siRNA.	Glycine	0-3	eukaryotic translation initiation factor 2 alpha kinase 3	Homo sapiens	193-197
21798518-8	2011	Intracellular dialysis of RGCs with the antibody against RGS2/RGS4 to block RGS2/RGS4 function gradually increased glycine current amplitudes of these cells.	Glycine	115-122	regulator of G-protein signaling 4	Rattus norvegicus	62-66
21798518-8	2011	Intracellular dialysis of RGCs with the antibody against RGS2/RGS4 to block RGS2/RGS4 function gradually increased glycine current amplitudes of these cells.	Glycine	115-122	regulator of G-protein signaling 2	Rattus norvegicus	76-80
24920668-4	2014	With stopped-flow absorption spectroscopy, we detected and confirmed the formation of the quinonoid intermediate upon reacting glycine with ALAS.	Glycine	127-134	aminolevulinic acid synthase 1	Mus musculus	140-144
25017909-4	2014	Isolated GluN1/GluN3A receptors integrated into lipid bilayers responded to addition of either glycine or d-serine, but not glutamate, with a ~1 nm reduction in height of the extracellular domain.	Glycine	95-102	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	15-21
21798518-8	2011	Intracellular dialysis of RGCs with the antibody against RGS2/RGS4 to block RGS2/RGS4 function gradually increased glycine current amplitudes of these cells.	Glycine	115-122	regulator of G-protein signaling 4	Rattus norvegicus	81-85
30511276-4	2019	Therefore, the aim of this study was to investigate the impact of the elastin-derived valine-glycine-valine-alanine-proline-glycine (VGVAPG) peptide on Ppargamma and beta-galactosidase (beta-Gal) expression in mouse cortical astrocytes in vitro.	Glycine	93-100	elastin	Mus musculus	70-77
21798518-9	2011	In the presence of the RGS2/RGS4 antibody melatonin-induced potentiation of glycine currents of RGCs was not observable.	Glycine	76-83	regulator of G-protein signaling 2	Rattus norvegicus	23-27
21798518-9	2011	In the presence of the RGS2/RGS4 antibody melatonin-induced potentiation of glycine currents of RGCs was not observable.	Glycine	76-83	regulator of G-protein signaling 4	Rattus norvegicus	28-32
21798518-10	2011	These results suggest that RGS2/RGS4 are coupled to melatonin receptor signaling in rat RGCs and these proteins may regulate the MT(2) receptor to change melatonin-induced modulation of glycine currents in rat RGCs.	Glycine	186-193	regulator of G-protein signaling 2	Rattus norvegicus	27-31
24899700-1	2014	Gephyrin, the principal scaffolding protein at inhibitory synapses, is essential for postsynaptic clustering of glycine and GABA type A receptors (GABA(A)Rs).	Glycine	112-119	gephyrin	Homo sapiens	0-8
30511276-4	2019	Therefore, the aim of this study was to investigate the impact of the elastin-derived valine-glycine-valine-alanine-proline-glycine (VGVAPG) peptide on Ppargamma and beta-galactosidase (beta-Gal) expression in mouse cortical astrocytes in vitro.	Glycine	93-100	galactosidase, beta 1	Mus musculus	166-184
30511276-4	2019	Therefore, the aim of this study was to investigate the impact of the elastin-derived valine-glycine-valine-alanine-proline-glycine (VGVAPG) peptide on Ppargamma and beta-galactosidase (beta-Gal) expression in mouse cortical astrocytes in vitro.	Glycine	124-131	elastin	Mus musculus	70-77
30511276-4	2019	Therefore, the aim of this study was to investigate the impact of the elastin-derived valine-glycine-valine-alanine-proline-glycine (VGVAPG) peptide on Ppargamma and beta-galactosidase (beta-Gal) expression in mouse cortical astrocytes in vitro.	Glycine	124-131	galactosidase, beta 1	Mus musculus	166-184
21798518-10	2011	These results suggest that RGS2/RGS4 are coupled to melatonin receptor signaling in rat RGCs and these proteins may regulate the MT(2) receptor to change melatonin-induced modulation of glycine currents in rat RGCs.	Glycine	186-193	regulator of G-protein signaling 4	Rattus norvegicus	32-36
30694168-8	2019	Finally, we found that leucine substitutions in putative glycine zipper motifs within TM helices of gM resulted in strong reduction of complex formation and decreased ability of gM to interfere with UL49.5-mediated major histocompatibility class I downregulation.	Glycine	57-64	envelope glycoprotein N	Bovine alphaherpesvirus 1	199-205
21627121-2	2011	Potent inhibition of Nek2 kinase activity in biochemical and cell-based assays required a noncatalytic cysteine residue (Cys22), located near the glycine-rich loop in a subset of human kinases.	Glycine	146-153	NIMA related kinase 2	Homo sapiens	21-25
24628546-6	2014	Genotyping demonstrated acquisition of a novel activating KRAS codon 13 GGC to GTT (glycine to valine) mutation, consistent with the observed resistance to upstream vascular endothelial growth factor receptor inhibition yet sensitivity to downstream MAPK kinase (MEK1/2) inhibition.	Glycine	84-91	mitogen-activated protein kinase kinase 1	Homo sapiens	263-269
24692540-8	2014	The Propeller residue Asp-150, which normally coordinates Arg of the ligand Arg-Gly-Asp motif, formed contacts with Arg-54 of the Fab that were expected to reduce soluble FN10 binding to cellular alphaVbeta3 complexed with 17E6.	Glycine	80-83	FA complementation group B	Homo sapiens	130-133
31016108-3	2019	Herein, mesoionic dye A1094 encapsulated in Arg-Gly-Asp-modified hepatitis B virus core protein (RGD-HBc) is designed and synthesized for effective NIR II PAI of brain gliomas.	Glycine	48-51	keratin 88, pseudogene	Homo sapiens	101-104
24700463-3	2014	The cytosolic tail of SelS consists of a coiled-coil domain, a putative VCP-interacting motif (VIM), and an unpronounced glycine- and proline-rich secondary structure.	Glycine	121-128	selenoprotein S	Homo sapiens	22-26
21563331-12	2004	A DOTA-Gly-benzoyl group was added to the C-terminus to form DOTA-Gly-benzoyl-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 (RM1).	Glycine	7-10	GCY	Homo sapiens	108-111
31490752-10	2019	A COL4A5 gene missense mutation, c.2156G&gt;A (p.G719E), located in the Gly-X-Y repeats of exon 28, was identified to co-segregate with the renal disorders in this family.	Glycine	72-75	collagen type IV alpha 5 chain	Homo sapiens	2-8
21310202-6	2011	Uptake of Gly-Sar by PEPT1 was decreased by indomethacin treatment, whereas the Gly-Sar plasma concentration was markedly increased in JBP485 co-treated rats.	Glycine	10-13	solute carrier family 15 member 1	Rattus norvegicus	21-26
24828203-2	2014	The MALDI-ISD spectra of bovine serum albumin (BSA), myoglobin and thioredoxin show discontinuous intense ion peaks originating from one-side preferential cleavage at the N-Calpha bond of Xxx-Asp, Xxx-Asn, Xxx-Cys and Gly-Xxx residues.	Glycine	218-221	thioredoxin	Homo sapiens	67-78
23529192-1	2014	GlyT1 and GlyT2 are the transporters responsible for glycine uptake from the synaptic cleft.	Glycine	53-60	solute carrier family 6 member 5	Rattus norvegicus	10-15
21388957-3	2011	The MAP family proteins undergo cleavage of their C-terminal residue(s), and the exposed conserved glycine forms conjugates with phosphatidylethanolamine, which associate with membranes.	Glycine	99-106	regulator of microtubule dynamics 1	Homo sapiens	4-7
23529192-6	2014	The functional characterization of GlyT1 and GlyT2 in cultured astrocytes performed by [(3)H]glycine uptake experiments revealed that both transporters take up glycine in a concentration-dependent way, but with a very distinct affinity.	Glycine	93-100	solute carrier family 6 member 5	Rattus norvegicus	45-50
30051972-0	2019	Identification of a novel growth hormone releasing peptide (a glycine analogue of GHRP-2) in a seized injection vial.	Glycine	62-69	ghrelin and obestatin prepropeptide	Homo sapiens	26-58
23529192-6	2014	The functional characterization of GlyT1 and GlyT2 in cultured astrocytes performed by [(3)H]glycine uptake experiments revealed that both transporters take up glycine in a concentration-dependent way, but with a very distinct affinity.	Glycine	160-167	solute carrier family 6 member 5	Rattus norvegicus	45-50
24795623-4	2014	Using cell culture models, we have defined the effects of R199W-DAO, and shown that it activates autophagy, leads to the formation of ubiquitinated aggregates and promotes apoptosis, all of which processes are attenuated by a D-serine/glycine site NMDAR antagonist.	Glycine	235-242	D-amino acid oxidase	Homo sapiens	64-67
21343294-3	2011	We now show that positively charged residues at the same loop 5 position boost also the conductance of anionic Cys-loop channels, such as glycine (alpha1 and alpha1beta) and GABA(A) (alpha1beta2gamma2) receptors.	Glycine	138-145	adrenoceptor alpha 1D	Homo sapiens	147-168
30500180-1	2018	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible conversion of l-serine and tetrahydrofolate into glycine and 5,10-methylenetetrahydrofolate.	Glycine	113-120	serine hydroxymethyltransferase 1	Homo sapiens	0-31
21276770-0	2011	Induction of integrin beta3 in PGE2-stimulated adhesion of mastocytoma P-815 cells to the Arg-Gly-Asp-enriched fragment of fibronectin.	Glycine	94-97	fibronectin 1	Mus musculus	123-134
24782709-1	2014	Gephyrin is a multifunctional scaffold protein essential for accumulation of inhibitory glycine and GABAA receptors at post-synaptic sites.	Glycine	88-95	gephyrin	Homo sapiens	0-8
30500180-1	2018	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible conversion of l-serine and tetrahydrofolate into glycine and 5,10-methylenetetrahydrofolate.	Glycine	113-120	serine hydroxymethyltransferase 1	Homo sapiens	33-37
24138986-4	2014	We investigated the mechanisms mediating the pathogenic effects of R199W DAO on motor neuron survival and showed that expression of glial R199W DAO is sufficient to induce apoptosis in cocultured motor neurons and this is sensitive to 5,7-dichloro-4-hydroxyquinoline-2-carboxylic acid, an N-methyl-d-aspartic acid receptor antagonist selective for the D-serine/glycine site.	Glycine	361-368	D-amino acid oxidase	Homo sapiens	144-147
21295342-2	2011	The presence of uniformly distributed fluorophore sequences, -Ser(Thr)-Tyr-Gly- along the molecular structure of rec1-resilin provides significant opportunity to synthesize fluorophore-modified AuNPs bioconjugates with unique photophysical properties.	Glycine	75-78	RAD1 checkpoint DNA exonuclease	Homo sapiens	113-117
30559931-9	2018	Metabolite profiling indicates the alteration of glycine in both lung cancer cells following treatment with miR-140 mimics.	Glycine	49-56	microRNA 140	Homo sapiens	108-115
24621206-12	2014	CONCLUSION: Decreased glycine excretion at V2 may indicate difficulties meeting the metabolic demands of the growing fetus, but urine profiles contained otherwise little indication of early adaptations during pregnancy towards reduced biological potential to breastfeed.	Glycine	22-29	nibrin	Homo sapiens	40-45
30464483-7	2018	Finally, Met/Met of COMT and Ser/Gly of DRD3 genes showed a predictive effect associated with the resistant-to-treatment phenotype.	Glycine	33-36	dopamine receptor D3	Homo sapiens	40-44
24369380-7	2014	Accordingly, only combined blockade of both GABAA- and glycine-gated Cl(-) channels replicated the effects of nerve injury or K(+)-Cl(-) co-transporter 2 blockade to their full extent.	Glycine	55-62	solute carrier family 12 member 5	Rattus norvegicus	126-153
21455495-3	2011	Here, we used structural analyses to identify a glycine-serine variation in the TCR that modulates antigen sensitivity.	Glycine	48-55	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	80-83
30264265-3	2018	Gephyrin self-assembles into a complex flat submembranous lattice that slows the lateral mobility of glycine and GABAA receptors, thus allowing for their clustering at postsynaptic sites.	Glycine	101-108	gephyrin	Homo sapiens	0-8
21241052-2	2011	Alanyl-tRNA synthetase (AlaRS) limits misacylation with glycine and serine by use of a dedicated editing domain, and a mutation in this activity has been genetically linked to a mouse model of a progressive neurodegenerative disease.	Glycine	56-63	alanyl-tRNA synthetase	Mus musculus	0-22
21241052-2	2011	Alanyl-tRNA synthetase (AlaRS) limits misacylation with glycine and serine by use of a dedicated editing domain, and a mutation in this activity has been genetically linked to a mouse model of a progressive neurodegenerative disease.	Glycine	56-63	alanyl-tRNA synthetase	Mus musculus	24-29
21308994-10	2011	A 3D reconstructed motoneuron model suggested that CFTR activity contributes to set the E(GABA/Gly) positive to the resting potential.	Glycine	95-98	CF transmembrane conductance regulator	Rattus norvegicus	51-55
21308994-12	2011	We propose that CFTR operated together with NKCC1 to produce depolarizing GABA/glycine mediated synaptic events.	Glycine	79-86	CF transmembrane conductance regulator	Rattus norvegicus	16-20
24716212-1	2014	BACKGROUND AND AIM: An increase in circulating concentrations of gastrin or gastrin precursors such as progastrin and glycine-extended gastrin has been proposed to promote the development of colorectal carcinomas (CRC).	Glycine	118-125	gastrin	Homo sapiens	65-72
24716212-1	2014	BACKGROUND AND AIM: An increase in circulating concentrations of gastrin or gastrin precursors such as progastrin and glycine-extended gastrin has been proposed to promote the development of colorectal carcinomas (CRC).	Glycine	118-125	gastrin	Homo sapiens	76-83
24716212-1	2014	BACKGROUND AND AIM: An increase in circulating concentrations of gastrin or gastrin precursors such as progastrin and glycine-extended gastrin has been proposed to promote the development of colorectal carcinomas (CRC).	Glycine	118-125	gastrin	Homo sapiens	76-83
29645274-2	2018	In this study we use a model marination solution comprising 0.2  mol L-1 glucose-0.2  mol L-1 glycine buffered to pH 4.3 containing either 0 or 50% ethanol and mimicked the cooking process by heating for 12 h. Antioxidative and antimutagenic characteristics of Maillard reaction products (MRPs) were investigated.	Glycine	94-101	L1 cell adhesion molecule	Mus musculus	90-93
24390199-8	2014	Genetic testing found a de novo glycine mutation within the COL4A2 triple helical domain.	Glycine	32-39	collagen type IV alpha 2 chain	Homo sapiens	60-66
24415781-4	2014	In human peripheral blood, TFL is dominantly expressed at the glycine- and tryptophan-rich cytoplasmic processing bodies of T lymphocytes, and it is persistently upregulated in activated T cells.	Glycine	62-69	zinc finger CCCH-type containing 12D	Homo sapiens	27-30
20884320-8	2011	MMP-7 shows a strong preference for Leu in P(1)" and also accepts Val, Gly, and Pro at this position, whereas Ala is not preferred at P(1)".	Glycine	71-74	matrix metallopeptidase 7	Homo sapiens	0-5
21178334-2	2011	In this study, we evaluated the role of p53 activation in glycerol-induced acute kidney injury (Gly-AKI).	Glycine	96-99	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	40-43
30251598-9	2018	Besides, Gly/Gly homozygotes for DRD3 rs6280 showed significantly lower maximum constriction velocity values.	Glycine	9-12	dopamine receptor D3	Homo sapiens	33-37
21178334-5	2011	RESULTS: Gly-AKI rats showed an increased renal expression of phosphorylated-p53.	Glycine	9-12	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	77-80
21389620-1	2011	Mammalian thioredoxin reductases (TrxRs) contain selenium as selenocysteine (Sec) in the C-terminal redox center -Gly-Cys-Sec-Gly-OH to reduce Trx and other substrates; a Sec-to-Cys substitution in mammalian TrxR yields an almost inactive enzyme.	Glycine	114-117	thioredoxin	Homo sapiens	34-37
21389620-1	2011	Mammalian thioredoxin reductases (TrxRs) contain selenium as selenocysteine (Sec) in the C-terminal redox center -Gly-Cys-Sec-Gly-OH to reduce Trx and other substrates; a Sec-to-Cys substitution in mammalian TrxR yields an almost inactive enzyme.	Glycine	126-129	thioredoxin	Homo sapiens	34-37
21935442-7	2011	An in vitro proteome-derived peptide library Nt-acetylation assay indicated that recombinant hNaa40p acetylates N-termini starting with the consensus sequence Ser-Gly-Gly-Gly-Lys-, strongly resembling the N-termini of the human histones H2A and H4.	Glycine	163-166	N-alpha-acetyltransferase 40, NatD catalytic subunit	Homo sapiens	93-100
21935442-7	2011	An in vitro proteome-derived peptide library Nt-acetylation assay indicated that recombinant hNaa40p acetylates N-termini starting with the consensus sequence Ser-Gly-Gly-Gly-Lys-, strongly resembling the N-termini of the human histones H2A and H4.	Glycine	167-170	N-alpha-acetyltransferase 40, NatD catalytic subunit	Homo sapiens	93-100
21935442-7	2011	An in vitro proteome-derived peptide library Nt-acetylation assay indicated that recombinant hNaa40p acetylates N-termini starting with the consensus sequence Ser-Gly-Gly-Gly-Lys-, strongly resembling the N-termini of the human histones H2A and H4.	Glycine	167-170	N-alpha-acetyltransferase 40, NatD catalytic subunit	Homo sapiens	93-100
23297802-6	2014	Despite these differences, there exists an interesting similarity between the two variants: both glutamates exert their function by modulating the conformation and interactions of glycine-rich motifs (G366-G367, G471-G473) resulting in an accumulation of binding incompetent gp120 conformations or a loss of intermolecular gp120-CD4 hydrogen bonds.	Glycine	180-187	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	275-280
23297802-6	2014	Despite these differences, there exists an interesting similarity between the two variants: both glutamates exert their function by modulating the conformation and interactions of glycine-rich motifs (G366-G367, G471-G473) resulting in an accumulation of binding incompetent gp120 conformations or a loss of intermolecular gp120-CD4 hydrogen bonds.	Glycine	180-187	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	323-328
23297802-7	2014	Thus, the present data suggests that interference with the structure and dynamics of glycine-rich stretches might represent a more widespread mechanism, by which gp120 mutations reduce binding affinity.	Glycine	85-92	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	162-167
24264576-3	2014	The zinc metalloendopeptidase, EC 3.4.24.15 (EP24.15), can cleave GnRH at the Tyr(5)-Gly(6) bond to form the pentapeptide, GnRH-(1-5).	Glycine	85-88	ADAM metallopeptidase with thrombospondin type 1 motif 3	Homo sapiens	4-29
24048732-5	2013	The receptor tetramers in erythroid precursor cells are composed of the NR1, NR2A, 2C, 2D, NR3A, and 3B subunits of which the glycine-binding NR3A and 3B and glutamate-binding NR2C and 2D subunits prevailed.	Glycine	126-133	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	91-95
24048732-5	2013	The receptor tetramers in erythroid precursor cells are composed of the NR1, NR2A, 2C, 2D, NR3A, and 3B subunits of which the glycine-binding NR3A and 3B and glutamate-binding NR2C and 2D subunits prevailed.	Glycine	126-133	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	142-146
30251598-9	2018	Besides, Gly/Gly homozygotes for DRD3 rs6280 showed significantly lower maximum constriction velocity values.	Glycine	13-16	dopamine receptor D3	Homo sapiens	33-37
30217234-7	2018	RESULTS: Ion channels exhibited cut-off effects associated with hydrocarbon molar water solubility in the following order of decreasing solubility: Nav1.2   Nav1.4   TRESK   TREK-1 &gt; GABAA &gt;&gt; glycine.	Glycine	201-208	sodium voltage-gated channel alpha subunit 4	Homo sapiens	157-163
30258351-0	2018	Structure-Function Relationships of Glycine and GABAA Receptors and Their Interplay With the Scaffolding Protein Gephyrin.	Glycine	36-43	gephyrin	Homo sapiens	113-121
24263033-6	2013	Genetic analysis of this individual showed a heterozygous transversion resulting in amino acid change from arginine to glycine in the PRX gene, suggesting CMT4F.	Glycine	119-126	periaxin	Homo sapiens	134-137
24263033-6	2013	Genetic analysis of this individual showed a heterozygous transversion resulting in amino acid change from arginine to glycine in the PRX gene, suggesting CMT4F.	Glycine	119-126	periaxin	Homo sapiens	155-160
24038877-0	2013	Position of glycine substitutions in the triple helix of COL6A1, COL6A2, and COL6A3 is correlated with severity and mode of inheritance in collagen VI myopathies.	Glycine	12-19	collagen type VI alpha 1 chain	Homo sapiens	57-63
24038877-0	2013	Position of glycine substitutions in the triple helix of COL6A1, COL6A2, and COL6A3 is correlated with severity and mode of inheritance in collagen VI myopathies.	Glycine	12-19	collagen type VI alpha 3 chain	Homo sapiens	77-83
24038877-2	2013	We describe clinical and genetic characteristics of 97 individuals with glycine substitutions in the TH domain of COL6A1, COL6A2, or COL6A3 and add a review of 97 published cases, for a total of 194 cases.	Glycine	72-79	collagen type VI alpha 1 chain	Homo sapiens	114-120
21738582-0	2011	N-terminal Gly(224)-Gly(411) domain in Listeria adhesion protein interacts with host receptor Hsp60.	Glycine	11-14	LAP	Homo sapiens	39-64
21738582-0	2011	N-terminal Gly(224)-Gly(411) domain in Listeria adhesion protein interacts with host receptor Hsp60.	Glycine	20-23	LAP	Homo sapiens	39-64
21738582-4	2011	METHODS: Using a ModBase structural model, LAP was divided into 4 putative subdomains: the ALDH region contains N1 (Met(1)-Pro(223)) and N2 (Gly(224)-Gly(411)), and the ADH region contains C1 (Gly(412)-Val(648)) and C2 (Pro(649)-Val(866)).	Glycine	141-144	LAP	Homo sapiens	43-46
21738582-4	2011	METHODS: Using a ModBase structural model, LAP was divided into 4 putative subdomains: the ALDH region contains N1 (Met(1)-Pro(223)) and N2 (Gly(224)-Gly(411)), and the ADH region contains C1 (Gly(412)-Val(648)) and C2 (Pro(649)-Val(866)).	Glycine	150-153	LAP	Homo sapiens	43-46
21738582-4	2011	METHODS: Using a ModBase structural model, LAP was divided into 4 putative subdomains: the ALDH region contains N1 (Met(1)-Pro(223)) and N2 (Gly(224)-Gly(411)), and the ADH region contains C1 (Gly(412)-Val(648)) and C2 (Pro(649)-Val(866)).	Glycine	150-153	LAP	Homo sapiens	43-46
24038877-2	2013	We describe clinical and genetic characteristics of 97 individuals with glycine substitutions in the TH domain of COL6A1, COL6A2, or COL6A3 and add a review of 97 published cases, for a total of 194 cases.	Glycine	72-79	collagen type VI alpha 3 chain	Homo sapiens	133-139
29991441-1	2018	Serine hydroxymethyltransferase (SHMT) is a pivotal enzyme in one-carbon metabolism that catalyses the reversible conversion of serine and tetrahydrofolate into glycine and methylenetetrahydrofolate.	Glycine	161-168	serine hydroxymethyltransferase 1	Homo sapiens	0-31
20977478-3	2010	Our previous quantitative trait loci analysis using C57BL/6 (B6) mice with better PPI performance and C3H/He (C3) with lower PPI score, shows that genes for both D-serine synthesizing enzyme and enzyme for reversible conversion between glycine and L-serine (Srr and Shmt1, respectively) are located in the same PPI-quantitative trait loci peak.	Glycine	236-243	serine racemase	Mus musculus	258-261
23687069-3	2013	An ELP matrix TGPG[VGRGD(VGVPG)6]20WPC (referred to as REP) contains multiple Arg-Gly-Asp motifs.	Glycine	82-85	nuclear receptor subfamily 5 group A member 1	Homo sapiens	3-6
29991441-1	2018	Serine hydroxymethyltransferase (SHMT) is a pivotal enzyme in one-carbon metabolism that catalyses the reversible conversion of serine and tetrahydrofolate into glycine and methylenetetrahydrofolate.	Glycine	161-168	serine hydroxymethyltransferase 1	Homo sapiens	33-37
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	156-163	semaphorin 3F	Homo sapiens	184-197
20541608-8	2010	In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active.	Glycine	164-171	semaphorin 3F	Homo sapiens	184-197
29991441-7	2018	The dissociation constant of 2.12 is 50-fold lower when it binds to SHMT1 enzyme-serine complex, as compared to the enzyme-glycine complex.	Glycine	123-130	serine hydroxymethyltransferase 1	Homo sapiens	68-73
30035852-2	2018	Depending on cell demands, serine hydroxymethyltransferase (SHMT) dynamically changes the fluxes of OCM by reversibly converting serine and tetrahydrofolate (THF) into 5,10-methylene-THF and glycine.	Glycine	191-198	serine hydroxymethyltransferase 1	Homo sapiens	27-58
21035103-5	2010	Sequence analysis of COL11A1 in two genetically independent fibrochondrogenesis cases demonstrated that each was a compound heterozygote for a loss-of-function mutation on one allele and a mutation predicting substitution for a conserved triple-helical glycine residue on the other.	Glycine	253-260	collagen type XI alpha 1 chain	Homo sapiens	21-28
24273285-6	2013	CONCLUSION: GLY can cause cellular damages, inhibit cell proliferation, induce cell apoptosis, and decrease expression of ABP and vimentin mRNAs in mouse Sertoli cells in vitro.	Glycine	12-15	secretoglobin, family 1B, member 29	Mus musculus	122-125
23736281-1	2013	RATIONALE: Inhibition of glycine transporter 1 (GlyT1) elevates extracellular glycine and can thus increase N-methyl-D-aspartate receptor (NMDAR) excitability in the brain.	Glycine	25-32	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	48-53
23736281-1	2013	RATIONALE: Inhibition of glycine transporter 1 (GlyT1) elevates extracellular glycine and can thus increase N-methyl-D-aspartate receptor (NMDAR) excitability in the brain.	Glycine	25-32	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	108-137
23736281-1	2013	RATIONALE: Inhibition of glycine transporter 1 (GlyT1) elevates extracellular glycine and can thus increase N-methyl-D-aspartate receptor (NMDAR) excitability in the brain.	Glycine	25-32	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	139-144
23736281-8	2013	RESULTS: When administered alone, acute SSR504734 enhanced PPI only at 30 mg/kg--a dose that has been shown to improve cognitive functions including working memory, which has been linked to enhanced NMDAR function resulting from the elevation of extracellular glycine.	Glycine	260-267	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	199-204
30035852-2	2018	Depending on cell demands, serine hydroxymethyltransferase (SHMT) dynamically changes the fluxes of OCM by reversibly converting serine and tetrahydrofolate (THF) into 5,10-methylene-THF and glycine.	Glycine	191-198	serine hydroxymethyltransferase 1	Homo sapiens	60-64
29947431-0	2018	Conserved aspartate-to-glycine mutation in tyrosinase is associated with albino phenotype in domestic guinea pigs (Cavia porcellus).	Glycine	23-30	tyrosinase	Cavia porcellus	43-53
24409760-5	2013	It was determined that choline, betaine, glycine, carnitine, acetoin and ectoine all improved the growth of R15 at cold.	Glycine	41-48	ribonuclease A family member 2	Rattus norvegicus	108-111
30532829-7	2011	Polymerase chain reaction (PCR) and sequencing of the PCR product showed a heterozygous missense mutation of codon 85 in the COL3A1 gene, which converted glycine to aspartic acid, and thus a diagnosis of EDS type IV was established.	Glycine	154-161	collagen type III alpha 1 chain	Homo sapiens	125-131
29901187-2	2018	In the current study, comprehensive bioinformatic analyses were performed to develop a novel scoring system for GC risk assessment based on CAP-Gly domain containing linker protein family member 4 (CLIP4) DNA methylation status.	Glycine	144-147	CAP-Gly domain containing linker protein family member 4	Homo sapiens	198-203
20637735-1	2010	Inhibition of the glycine transporter type 1 (GlyT1) leading to potentiation of the glycine site (GlyB) on the N-methyl-d-aspartate (NMDA) receptor has been proposed as a novel therapeutic approach for schizophrenia.	Glycine	18-25	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	46-51
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	52-57
24060848-6	2013	The results clearly indicate that ANP acts directly on glycinergic presynaptic nerve terminals to inhibit glycine release via presynaptic NPR-A.	Glycine	55-62	natriuretic peptide receptor 1	Rattus norvegicus	138-143
20880398-3	2010	The aim of the present study was to investigate SLC36A1-mediated transport of Gly-Gly and Gly-Gly mimetics, and to investigate Gly-Sar transport via SLC36A1 and the proton-coupled dipeptide/tripeptide transporter, SLC15A1 in Caco-2 cells.	Glycine	78-81	solute carrier family 36 member 1	Homo sapiens	48-55
30140255-9	2018	In agreement with the in vitro results, the in vivo findings demonstrated that Pro-Gly, but not Pro plus Gly, stimulated the expression and secretion of IGF-1 and activated JAK2/STAT5 signaling pathway in the liver of mice injected with Pro-Gly or Pro+Gly acutely or chronically.	Glycine	83-86	Janus kinase 2	Mus musculus	173-177
20880398-3	2010	The aim of the present study was to investigate SLC36A1-mediated transport of Gly-Gly and Gly-Gly mimetics, and to investigate Gly-Sar transport via SLC36A1 and the proton-coupled dipeptide/tripeptide transporter, SLC15A1 in Caco-2 cells.	Glycine	82-85	solute carrier family 36 member 1	Homo sapiens	48-55
20880398-3	2010	The aim of the present study was to investigate SLC36A1-mediated transport of Gly-Gly and Gly-Gly mimetics, and to investigate Gly-Sar transport via SLC36A1 and the proton-coupled dipeptide/tripeptide transporter, SLC15A1 in Caco-2 cells.	Glycine	82-85	solute carrier family 36 member 1	Homo sapiens	48-55
20880398-3	2010	The aim of the present study was to investigate SLC36A1-mediated transport of Gly-Gly and Gly-Gly mimetics, and to investigate Gly-Sar transport via SLC36A1 and the proton-coupled dipeptide/tripeptide transporter, SLC15A1 in Caco-2 cells.	Glycine	82-85	solute carrier family 36 member 1	Homo sapiens	48-55
23733502-13	2013	Taken together, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCalpha activation through Src kinase.	Glycine	41-48	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	65-70
30140255-9	2018	In agreement with the in vitro results, the in vivo findings demonstrated that Pro-Gly, but not Pro plus Gly, stimulated the expression and secretion of IGF-1 and activated JAK2/STAT5 signaling pathway in the liver of mice injected with Pro-Gly or Pro+Gly acutely or chronically.	Glycine	83-86	signal transducer and activator of transcription 5A	Mus musculus	178-183
20880398-3	2010	The aim of the present study was to investigate SLC36A1-mediated transport of Gly-Gly and Gly-Gly mimetics, and to investigate Gly-Sar transport via SLC36A1 and the proton-coupled dipeptide/tripeptide transporter, SLC15A1 in Caco-2 cells.	Glycine	82-85	solute carrier family 36 member 1	Homo sapiens	48-55
20880398-7	2010	KEY RESULTS In SLC36A1-expressing oocytes, an inward current was induced by Gly-Sar, Gly-Gly, delta-aminolevulinic acid, beta-aminoethylglycine, delta-aminopentanoic acid, GABA, Gly and Pro, whereas Val, Leu, mannitol, 5-HTP and the dipeptides Gly-Ala, Gly-Pro and Gly-Phe did not evoke currents.	Glycine	76-79	solute carrier family 36 member 1	Homo sapiens	15-22
30042874-1	2018	Background: Somatic point substitution mutations in the KRAS proto-oncogene primarily affect codons 12/13 where glycine is converted into other amino acids, and are highly prevalent in pancreatic, colorectal, and non-small cell lung cancers.	Glycine	112-119	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	56-60
23841814-10	2013	Binding of the moAb is abrogated by introduction of two Gly residues in the D-J junction of the CDR3 of the beta-chain.	Glycine	56-59	cerebellar degeneration-related 3	Mus musculus	96-100
29648983-4	2018	Activation of the NMDAR requires occupation of the glycine-modulatory site by co-agonists to achieve its synaptic functions.	Glycine	51-58	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	18-23
23414300-1	2013	H3F3A mutations are seen in ~30% of pediatric glioblastoma (GBMs) and involve either the lysine residue at position 27 (K27M) or glycine at position 34 (G34R/V).	Glycine	129-136	H3.3 histone A	Homo sapiens	0-5
23624368-7	2013	As regards, p27 Val109Gly, both heterozygous and homozygous Gly genotypes were shown to be protective genotypes on calculating both crude and adjusted odds ratios (ORs) for age, sex, and educational level [OR 0.37; 95% confidence interval (CI) 0.16-0.87; P&lt;0.05].	Glycine	22-25	interferon alpha inducible protein 27	Homo sapiens	12-15
23624368-9	2013	The p27 Gly protective genotype decreased the risk for melanoma in a stratified analysis of the known risk factors such as hair and eye color, sunburns, pigmented lesions, and European ancestry.	Glycine	8-11	interferon alpha inducible protein 27	Homo sapiens	4-7
20838240-2	2010	The maintenance of a low-intracellular chloride concentration by the potassium chloride cotransporter 2 (KCC2) is essential for the efficacy of fast synaptic inhibition of mature motoneurons in response to the activation of ionotropic gamma-aminobutyric acid A and glycine receptors.	Glycine	265-272	solute carrier family 12, member 5	Mus musculus	105-109
20571078-10	2010	Moreover, [d-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO) treatment increased both reporter promoter activity and Sult4a1 levels in mu-opioid receptor expressing Neuro2a/mu-opioid receptor cells, and EMSAs showed this to be due to increased binding of CREB and ATF-2 to the Sult4a1 promoter.	Glycine	31-34	sulfotransferase family 4A, member 1	Mus musculus	116-123
20571078-10	2010	Moreover, [d-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO) treatment increased both reporter promoter activity and Sult4a1 levels in mu-opioid receptor expressing Neuro2a/mu-opioid receptor cells, and EMSAs showed this to be due to increased binding of CREB and ATF-2 to the Sult4a1 promoter.	Glycine	31-34	sulfotransferase family 4A, member 1	Mus musculus	276-283
23457254-0	2013	Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1.	Glycine	29-36	transcriptional regulator	Pseudomonas aeruginosa PAO1	5-11
23457254-4	2013	Using a combination of microarray and metabolite analyses, we demonstrate that the assimilation of glycine as a carbon source and the biosynthesis of pyocyanin in Pseudomonas aeruginosa PAO1 are both dependent on the PA2449 gene.	Glycine	99-106	transcriptional regulator	Pseudomonas aeruginosa PAO1	217-223
23457254-5	2013	The inactivation of the PA2449 gene was found to influence the transcription of a core set of genes encoding a glycine cleavage system, serine hydroxymethyltransferase, and serine dehydratase.	Glycine	111-118	transcriptional regulator	Pseudomonas aeruginosa PAO1	24-30
30050902-5	2018	Moreover, we identified that glycine signaling in NSCs is associated with several common developmental pathways and surprisingly also the p53-related apoptosis.	Glycine	29-36	tumor protein p53	Danio rerio	138-141
23457254-8	2013	PA2449 is conserved among pseudomonads and might be universally involved in the assimilation of glycine among this metabolically diverse group of bacteria.	Glycine	96-103	transcriptional regulator	Pseudomonas aeruginosa PAO1	0-6
23423655-4	2013	Recently, we proposed that this transformation, an N-S acyl shift, is accelerated by a localized conformational strain, between the intein"s catalytic cysteine (Cys1) and the neighboring glycine (Gly-1) in the N-extein.	Glycine	187-194	cystin 1	Homo sapiens	161-165
20435060-1	2010	Thioredoxin 1 (Trx 1) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys- that is ubiquitously present in the human body.	Glycine	92-95	thioredoxin	Homo sapiens	0-13
20435060-1	2010	Thioredoxin 1 (Trx 1) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys- that is ubiquitously present in the human body.	Glycine	92-95	thioredoxin	Homo sapiens	15-20
30050902-7	2018	First, we showed by two approaches, acridine orange staining and active caspase 3 immunostaining that defects in glycine signaling induce an early and transient cell death, which was suppressed by knockdown of p53.	Glycine	113-120	caspase 3, apoptosis-related cysteine peptidase a	Danio rerio	72-81
30050902-7	2018	First, we showed by two approaches, acridine orange staining and active caspase 3 immunostaining that defects in glycine signaling induce an early and transient cell death, which was suppressed by knockdown of p53.	Glycine	113-120	tumor protein p53	Danio rerio	210-213
20860469-11	2010	The rs6280 variant (Ser9Gly) of the dopamine receptor 3 (DRD3) gene may influence the binding affinity of D3 receptors as a result of serine to glycine substitution of the receptor protein.	Glycine	144-151	dopamine receptor D3	Homo sapiens	57-61
23357641-1	2013	Nephronectin is a basement membrane protein comprising five N-terminal epidermal growth factor (EGF)-like repeats, a central linker segment containing an Arg-Gly-Asp (RGD) motif and a C-terminal meprin-A5 protein-receptor protein tyrosine phosphatase mu (MAM) domain.	Glycine	158-161	nephronectin	Mus musculus	0-12
30050902-11	2018	We found that disruption of glycine signaling induced a drastic and selective loss of nestin-positive (nestin+) NSCs, which was only partially rescued upon p53 knockdown.	Glycine	28-35	tumor protein p53	Danio rerio	156-159
29996845-3	2018	In the case of Foamy viruses, genome encapsidation is mediated by Gag C-terminal domain (CTD), which harbors three clusters of glycine and arginine residues named GR boxes (GRI-III).	Glycine	127-134	Pr76 polyprotein precursor	Rous sarcoma virus	66-69
22933181-7	2013	Molecular modeling of the retroviral domain of the Ddi1-like Leishmania protein revealed a dimer structure that contained a double Asp-Ser-Gly-Ala amino acid sequence motif, in an almost identical geometry to the exhibited by the homologous retroviral aspartyl protease domain of yeast Ddi1 protein.	Glycine	139-142	Ddi1p	Saccharomyces cerevisiae S288C	51-55
20561511-11	2010	These data suggest that both PKA and PKC can modulate GABA and glycine release in rat VCN neurons.	Glycine	63-70	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	29-32
29500820-4	2018	One approach to increase synaptic glycine is to inhibit the activity of the glycine transporter 2 (GlyT2) on inhibitory nerve terminals.	Glycine	34-41	solute carrier family 6 member 5	Rattus norvegicus	76-97
20691033-8	2010	Surprisingly, however, substitution of F122 with Ala or Gly, but not with Trp, increased the Alix-binding capacity in binding assays.	Glycine	56-59	programmed cell death 6 interacting protein	Homo sapiens	93-97
23268205-6	2013	The PepT1 transporter of these species has very low affinity for Lys-Lys and Gly-Lys; this reduces the transport efficiency which is instead higher for Lys-Met and Lys-Gly.	Glycine	77-80	solute carrier family 15 member 1	Oryctolagus cuniculus	4-9
29500820-4	2018	One approach to increase synaptic glycine is to inhibit the activity of the glycine transporter 2 (GlyT2) on inhibitory nerve terminals.	Glycine	34-41	solute carrier family 6 member 5	Rattus norvegicus	99-104
20200225-4	2010	Mutation analyses of MyoK revealed that both a C-terminal farnesylation membrane anchor and a Gly-Pro-Arg domain that interacts with profilin and Abp1 were necessary for proper localization in the furrow and efficient phagocytosis.	Glycine	94-97	Abp1p	Saccharomyces cerevisiae S288C	146-150
29500820-6	2018	Inhibiting activity of GlyT2 increases synaptic glycine, which decreases excitability in nociceptive circuits and provides analgesia in neuropathic and inflammatory pain models.	Glycine	48-55	solute carrier family 6 member 5	Rattus norvegicus	23-28
29989088-8	2018	We herein report 4 novel inhibitor candidates of Asp-Ile-Phe, Asp-Ile-Tyr, Asp-Ile-Lys and Hser-Gly-Phe with high potency and selectivity binding to MMP-2, as well as 6 novel inhibitor candidates of Chg-Ile-Ile, Chg-Ile-Leu, Chg-Ile-Glu, Chg-Ile-Met, Chg-Val-Ile and Chg-Val-Leu selectively binding to MMP-7.	Glycine	96-99	matrix metallopeptidase 7	Homo sapiens	302-307
20308327-0	2010	A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.	Glycine	2-9	heterogeneous nuclear ribonucleoprotein H2	Homo sapiens	25-32
20308327-0	2010	A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.	Glycine	2-9	transportin 1	Homo sapiens	119-132
23334558-1	2013	The tautomerization process of glycine between the neutral (NE) and zwitterionic (ZW) forms in aqueous solution was explored theoretically using the conductor-like polarizable continuum model (CPCM) by adopting the PAULING cavity model at the B3LYP, MP2 and CCSD levels with the 6-311+G(d,p) basis set.	Glycine	31-38	tryptase pseudogene 1	Homo sapiens	250-253
30456347-1	2018	Breakdown of serine by the enzyme serine hydroxymethyltransferase (SHMT) produces glycine and one-carbon (1C) units.	Glycine	82-89	serine hydroxymethyltransferase 1	Homo sapiens	34-65
23426681-1	2013	D-Serine and glycine are coagonists of NMDA receptors (NMDARs), but their relative contributions for several NMDAR-dependent processes are unclear.	Glycine	13-20	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	55-60
23426681-2	2013	We now report that the alanine-serine-cysteine transporter-1 (Asc-1) mediates release of both D-serine and glycine from neurons, and, in turn, this modulates NMDAR synaptic activity.	Glycine	107-114	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	158-163
23426681-9	2013	Furthermore, NMDAR synaptic potentials are preserved in SR-KO mice and are also enhanced by D-Ile, indicating that glycine overlaps with D-serine binding at synaptic NMDARs.	Glycine	115-122	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	13-18
23426681-10	2013	Altogether, our results disclose a novel role of Asc-1 in regulating NMDAR-dependent synaptic activity by mediating concurrent non-vesicular release of D-serine and glycine.	Glycine	165-172	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	69-74
22821706-4	2013	Syt2-labeled cells were immunoreactive for glycine but lacked immunoreactivity for gamma-aminobutyric acid (GABA), suggesting they use glycine as their neurotransmitter.	Glycine	43-50	synaptotagmin 2	Homo sapiens	0-4
20154084-1	2010	Atg18 and Atg21 are homologous WD-40 repeat proteins that bind phosphoinositides via a novel conserved Phe-Arg-Arg-Gly motif and function in autophagy-related pathways.	Glycine	115-118	WD repeat domain, phosphoinositide interacting 1	Homo sapiens	0-5
20345904-6	2010	With respect to the cleavage site specificities, the study revealed that all three MMPs similarly tolerate hydrophobic and/or aliphatic amino acids, including Pro, Gly, Ile, and Val, at P(1)".	Glycine	164-167	matrix metallopeptidase 7	Homo sapiens	83-87
22821706-4	2013	Syt2-labeled cells were immunoreactive for glycine but lacked immunoreactivity for gamma-aminobutyric acid (GABA), suggesting they use glycine as their neurotransmitter.	Glycine	135-142	synaptotagmin 2	Homo sapiens	0-4
30456347-1	2018	Breakdown of serine by the enzyme serine hydroxymethyltransferase (SHMT) produces glycine and one-carbon (1C) units.	Glycine	82-89	serine hydroxymethyltransferase 1	Homo sapiens	67-71
29867346-4	2018	Here, we studied the effects of protein kinase C (PKC) and cAMP-dependent protein kinase A (PKA) on glycine induced currents in HEK293 cells expressing human homomeric alpha1 and heteromeric alpha1-beta GlyRs using whole-cell patch clamp techniques as well as internalization assays.	Glycine	100-107	adrenoceptor alpha 1D	Homo sapiens	168-208
23264625-7	2013	AHSP binding also dramatically reduces the redox potential of alpha-subunits, from +40 to -78 mV in 1 m glycine buffer, pH 6.0, at 8  C, demonstrating independently that AHSP has a much higher affinity for Fe(III) versus Fe(II) alpha-subunits.	Glycine	104-111	alpha hemoglobin stabilizing protein	Homo sapiens	0-4
29407767-5	2018	A point-mutation of S296A in TM3 of alpha1 GlyRs significantly inhibits DH-CBD potentiation of glycine currents (IGly) in HEK-293 cells and neurons in lamina I-II of spinal cord slices.	Glycine	95-102	glycine receptor alpha 1	Homo sapiens	36-48
23264625-7	2013	AHSP binding also dramatically reduces the redox potential of alpha-subunits, from +40 to -78 mV in 1 m glycine buffer, pH 6.0, at 8  C, demonstrating independently that AHSP has a much higher affinity for Fe(III) versus Fe(II) alpha-subunits.	Glycine	104-111	alpha hemoglobin stabilizing protein	Homo sapiens	170-174
20071328-3	2010	Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties.	Glycine	97-100	secreted phosphoprotein 1	Homo sapiens	140-143
20070946-1	2010	A glycine-rich motif described as being involved in human polymerase delta proliferating cell nuclear antigen (PCNA) binding has also been identified in all euryarchaeal DNA polymerase D (Pol D) family members.	Glycine	2-9	proliferating cell nuclear antigen	Homo sapiens	111-115
29576319-2	2018	Here, we show that the CAP-Gly and coiled-coil domains of Bik1 interact with the C-terminal ETF peptide of Bim1 and the C-terminal tail region of Stu2, respectively.	Glycine	27-30	TEA domain transcription factor 2	Homo sapiens	92-95
23065292-5	2013	Meta-analysis of six studies showed a significant association between the Gly/Gly+Gly/Asp genotype of the TLR4 Asp299Gly polymorphism and vasculitis and GCA (Odds ratio [OR] = 1.368, 95 % confidence interval [CI] = 1.300-1.815, p = 0.030; OR = 1.523, 95 % CI = 1.099-2.112, p = 0.012).	Glycine	74-77	toll like receptor 4	Homo sapiens	106-110
23065292-5	2013	Meta-analysis of six studies showed a significant association between the Gly/Gly+Gly/Asp genotype of the TLR4 Asp299Gly polymorphism and vasculitis and GCA (Odds ratio [OR] = 1.368, 95 % confidence interval [CI] = 1.300-1.815, p = 0.030; OR = 1.523, 95 % CI = 1.099-2.112, p = 0.012).	Glycine	78-81	toll like receptor 4	Homo sapiens	106-110
29576319-2	2018	Here, we show that the CAP-Gly and coiled-coil domains of Bik1 interact with the C-terminal ETF peptide of Bim1 and the C-terminal tail region of Stu2, respectively.	Glycine	27-30	Stu2p	Saccharomyces cerevisiae S288C	146-150
23065292-5	2013	Meta-analysis of six studies showed a significant association between the Gly/Gly+Gly/Asp genotype of the TLR4 Asp299Gly polymorphism and vasculitis and GCA (Odds ratio [OR] = 1.368, 95 % confidence interval [CI] = 1.300-1.815, p = 0.030; OR = 1.523, 95 % CI = 1.099-2.112, p = 0.012).	Glycine	78-81	toll like receptor 4	Homo sapiens	106-110
23065292-6	2013	Under a random effects model, the adjusted ORs calculated using the trim and fill technique revealed an association between the Gly/Gly+Gly/Asp genotype of the TLR4 Asp299Gly polymorphism and vasculitis (OR = 1.544, 95 % CI = 1.091-2.185, p &lt; 0.05).	Glycine	128-131	toll like receptor 4	Homo sapiens	160-164
19780137-8	2010	The absorptive permeability of LY544344 was reduced to approximately 5% of control in the presence of excess Gly-Sar, a known PEPT1 substrate.	Glycine	109-112	solute carrier family 15 member 1	Rattus norvegicus	126-131
29304076-4	2018	Full activation of NMDAR requires binding of agonist glutamate and coagonist glycine or D-serine.	Glycine	77-84	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	19-24
20081141-2	2010	Neuronal isoform glycine transporter-2 (GlyT2) reuptakes presynaptically released glycine and regulates the glycinergic neurotransmission.	Glycine	17-24	solute carrier family 6 member 5	Rattus norvegicus	40-45
19544076-1	2010	The variation in reaction dynamics of OH hydrogen abstraction from glycine between HF, MP2, CCSD(T), M05-2X, BHandHLYP, and B3LYP levels was demonstrated.	Glycine	67-74	tryptase pseudogene 1	Homo sapiens	87-90
20635792-4	2010	Exon-specific amplification of genomic DNA by polymerase chain reaction followed by direct sequence analysis revealed a novel homozygous missense mutation at codon 48 in the C1q C gene causing a glycine-to-arginine substitution affecting the collagen-like region of C1q.	Glycine	195-202	complement C1q A chain	Homo sapiens	174-177
20358044-2	2010	A Strecker-type synthesis of glycine by reacting NH(3), H(2)C=O and HCN in presence of ice water (H(2)O-ice) as a catalyst has been theoretically studied at B3LYP/6-31+G(d,p) level within a cluster approach in order to mimic reactions occurring in the interstellar and circumstellar medium (ICM).	Glycine	29-36	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	68-71
19926721-6	2010	The C-terminal portion of hnRNP H that contains the glycine-rich domains (GRD) is essential for splicing activity, and it can be functionally replaced by the GRD of hnRNP A1.	Glycine	52-59	heterogeneous nuclear ribonucleoprotein H2	Homo sapiens	26-33
19768812-0	2010	[Gly(14)]-humanin rescues long-term potentiation from amyloid beta protein-induced impairment in the rat hippocampal CA1 region in vivo.	Glycine	1-4	carbonic anhydrase 1	Rattus norvegicus	117-120
19875446-0	2009	Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport.	Glycine	67-74	solute carrier family 6 member 5	Rattus norvegicus	31-36
19875446-1	2009	Concentrations of extracellular glycine in the central nervous system are regulated by Na(+)/Cl(-)-dependent glycine transporters, GLYT1 and GLYT2.	Glycine	32-39	solute carrier family 6 member 5	Rattus norvegicus	141-146
19877718-5	2009	Replacement of a central Gly in the neuromodulin IQ domain with a Lys at this position in PEP19 almost entirely accounts for the distinctive patterns of Ca(2+)-dependent stability changes exhibited by the two complexes.	Glycine	25-28	growth associated protein 43	Homo sapiens	36-48
20010690-2	2009	Throughout evolution, two editing checkpoints prevent disease-causing mistranslation from confusing glycine or serine for alanine at the active site of AlaRS.	Glycine	100-107	alanyl-tRNA synthetase 2, mitochondrial	Mus musculus	152-157
20010690-5	2009	The paradox of misincorporating both a smaller (glycine) and a larger (serine) amino acid suggests a deep conflict for nature-designed AlaRS.	Glycine	48-55	alanyl-tRNA synthetase 2, mitochondrial	Mus musculus	135-140
19626700-2	2009	We tested the hypothesis that the common nonsynonymous genetic variants in M6P/IGF2R c.901C &gt; G (Leu &gt; Val) in exon 6 and c.5002G &gt; A (Gly &gt; Arg) in exon 34 are associated with risk of esophageal and gastric cancers.	Glycine	144-147	insulin like growth factor 2 receptor	Homo sapiens	75-84
19798595-7	2009	Fibulin-5 contains an evolutionally conserved arginine-glycine-aspartic acid (RGD) motif in the N-terminal region, which mediates binding to a subset of integrins, including alpha5beta1, alphavbeta3, and alphavbeta5.	Glycine	55-62	fibulin 5	Mus musculus	0-9
23065292-6	2013	Under a random effects model, the adjusted ORs calculated using the trim and fill technique revealed an association between the Gly/Gly+Gly/Asp genotype of the TLR4 Asp299Gly polymorphism and vasculitis (OR = 1.544, 95 % CI = 1.091-2.185, p &lt; 0.05).	Glycine	132-135	toll like receptor 4	Homo sapiens	160-164
23065292-6	2013	Under a random effects model, the adjusted ORs calculated using the trim and fill technique revealed an association between the Gly/Gly+Gly/Asp genotype of the TLR4 Asp299Gly polymorphism and vasculitis (OR = 1.544, 95 % CI = 1.091-2.185, p &lt; 0.05).	Glycine	132-135	toll like receptor 4	Homo sapiens	160-164
23711138-8	2013	Overall, these results suggest that there are compounds in WS with possible glycine mimetic activities, which may be potential targets for inducing memory consolidation in hippocampal CA1 neurons.	Glycine	76-83	NLR family, pyrin domain containing 3	Mus musculus	59-61
23711493-11	2013	According to Ussing chamber experiments pharmacological JAK2 inhibition similarly decreased Igly-gly in mouse intestine.	Glycine	93-96	Janus kinase 2	Mus musculus	56-60
23573143-4	2013	The expression level of phosphorylated FAK, Akt, ERK1/2, and Rb was decreased p21 expression while level was increased in WEHI-3 treated with GLY.	Glycine	142-145	PTK2 protein tyrosine kinase 2	Mus musculus	39-42
23573143-8	2013	Accordingly, GLY demonstrated an inhibitory effect on tumor growth with a regulatory mechanism partially through inhibiting FAK, Akt, and ERK expression in WEHI-3 cells.	Glycine	13-16	PTK2 protein tyrosine kinase 2	Mus musculus	124-127
23948919-12	2013	Genetic testing revealed a heterozygous guanine to cytosine mutation at the first base of codon 389 (Exon 13) of MAPT, the tau gene, resulting in a glycine to arginine substitution, in the patient and her non-affected father.	Glycine	148-155	microtubule associated protein tau	Homo sapiens	113-117
23948919-12	2013	Genetic testing revealed a heterozygous guanine to cytosine mutation at the first base of codon 389 (Exon 13) of MAPT, the tau gene, resulting in a glycine to arginine substitution, in the patient and her non-affected father.	Glycine	148-155	microtubule associated protein tau	Homo sapiens	123-126
22877924-9	2012	Significant interaction effects for the BDNF Val66Met Val/Val genotype and both DRD3 Ser9Gly Ser/Ser and Ser/Gly genotypes were found only in bipolar-II patients (P=0.027 and 0.006, respectively).	Glycine	89-92	dopamine receptor D3	Homo sapiens	80-84
23051648-3	2012	Several independent unc-17 alleles are associated with a glycine-to-arginine substitution (G347R), which introduces a positive charge in the ninth transmembrane domain (TMD) of UNC-17.	Glycine	57-64	Vesicular acetylcholine transporter unc-17	Caenorhabditis elegans	20-26
23051648-3	2012	Several independent unc-17 alleles are associated with a glycine-to-arginine substitution (G347R), which introduces a positive charge in the ninth transmembrane domain (TMD) of UNC-17.	Glycine	57-64	Vesicular acetylcholine transporter unc-17	Caenorhabditis elegans	177-183
23051648-7	2012	Two independent suppressor alleles of sup-1 are associated with a glycine-to-glutamic acid substitution (G84E), resulting in a negative charge in the SUP-1 TMD.	Glycine	66-73	Protein SUP-1	Caenorhabditis elegans	38-43
23051648-7	2012	Two independent suppressor alleles of sup-1 are associated with a glycine-to-glutamic acid substitution (G84E), resulting in a negative charge in the SUP-1 TMD.	Glycine	66-73	Protein SUP-1	Caenorhabditis elegans	150-155
22802013-7	2012	Glucose uptake and glucose oxidation to CO(2) increased in 1 h and the conversion of glucose to lipids increased at 3 h. In addition, glycine oxidation to CO(2) and conversion of glycine to lipids increased at 1 h, whereas the incorporation of glycine in proteins decreased at 1 and 3 h. Methylglyoxal decreased glyoxalase I and II activities and increased AGEs content within 24 h. Lactate oxidation and lactate levels were not modified by methylglyoxal exposure.	Glycine	134-141	glyoxalase I	Homo sapiens	312-324
23103428-2	2012	Intriguingly, in the parasitic wasp Nasonia vitripennis its members (termed nabaecin-1 to -3) have gained a carboxyl terminal glycine-rich antimicrobial unit through exon-shuffling.	Glycine	126-133	nabaecin-1	Nasonia vitripennis	76-92
22975709-6	2012	Glycine-induced membrane currents mediated by PAT1 were measured using the two-electrode voltage clamp technique.	Glycine	0-7	solute carrier family 36 member 1	Homo sapiens	46-50
23064226-2	2012	Specifically, they overexpress the M2 isoform of the tightly regulated enzyme pyruvate kinase (PKM2), which controls glycolytic flux, and are highly dependent on de novo biosynthesis of serine and glycine.	Glycine	197-204	pyruvate kinase M1/2	Homo sapiens	95-99
22968170-6	2012	The unmethylated arginine-glycine-glycine domain preceding the PY-NLS interacts with TRN and arginine methylation in this domain reduces TRN binding.	Glycine	26-33	transportin 1	Homo sapiens	85-88
22968170-6	2012	The unmethylated arginine-glycine-glycine domain preceding the PY-NLS interacts with TRN and arginine methylation in this domain reduces TRN binding.	Glycine	26-33	transportin 1	Homo sapiens	137-140
22968170-6	2012	The unmethylated arginine-glycine-glycine domain preceding the PY-NLS interacts with TRN and arginine methylation in this domain reduces TRN binding.	Glycine	34-41	transportin 1	Homo sapiens	85-88
22968170-6	2012	The unmethylated arginine-glycine-glycine domain preceding the PY-NLS interacts with TRN and arginine methylation in this domain reduces TRN binding.	Glycine	34-41	transportin 1	Homo sapiens	137-140
23106172-5	2012	Furthermore, the label incorporation pattern in the major mass spectral fragment at m/z 67 indicated that the C-2 atoms originating from glycine reside in the ring system of 2,3-dimethylpyrazine.	Glycine	137-144	complement C2	Homo sapiens	110-113
23042809-7	2012	One mutation produced a premature stop codon at position 312 of the protein, while the second mutation induced a frameshift in the last exon, producing a stop codon that truncated the extreme C-terminus of DAPLE, including the 2026-2028 Gly-Cys-Val motif known to bind the post synaptic density protein (PSD95), Drosophila disc large tumor suppressor (Dlg1), and zonula occludens-1 protein (zo-1) (PDZ) domain of Dishevelled.	Glycine	237-240	coiled-coil domain containing 88C	Homo sapiens	206-211
22819077-9	2012	Glycine substitution of the conserved amino acid residue Glu261 of APN-1, corresponding to Glu145 involved in coordinating Zn(2+) ions in the active site pocket of E. coli endonuclease IV, resulted in an inactive variant that lose the ability to rescue the DNA repair defects of S. cerevisiae apn1Deltaapn2Deltatpp1Delta mutant.	Glycine	0-7	DNA-(apurinic or apyrimidinic site) lyase APN1	Saccharomyces cerevisiae S288C	67-72
22785121-3	2012	In contrast, function was preserved when Gly-56 and Gly-59 (the other conservative GXXG motif in human PCFT) were replaced with alanine.	Glycine	52-55	solute carrier family 46 member 1	Homo sapiens	103-107
22785121-4	2012	Similarly, Gly-93 and Gly-97, which constitute the only conserved GXXXG dimerization motif in human PCFT, tolerated alanine substitution.	Glycine	11-14	solute carrier family 46 member 1	Homo sapiens	100-104
22785121-4	2012	Similarly, Gly-93 and Gly-97, which constitute the only conserved GXXXG dimerization motif in human PCFT, tolerated alanine substitution.	Glycine	22-25	solute carrier family 46 member 1	Homo sapiens	100-104
22785121-7	2012	The functional role of residues around Gly-189 and Gly-192 is consistent with a molecular structural model in which these two residues along with Ieu-188 are accessible to the PCFT aqueous translocation pathway.	Glycine	39-42	solute carrier family 46 member 1	Homo sapiens	176-180
22785121-7	2012	The functional role of residues around Gly-189 and Gly-192 is consistent with a molecular structural model in which these two residues along with Ieu-188 are accessible to the PCFT aqueous translocation pathway.	Glycine	51-54	solute carrier family 46 member 1	Homo sapiens	176-180
23341755-3	2012	The common (non Gly, Pro) backbone CMAP potential has been refined against experimental solution NMR data for weakly structured peptides, resulting in a rebalancing of the energies of the alpha-helix and extended regions of the Ramachandran map, correcting the alpha-helical bias of CHARMM22/CMAP.	Glycine	16-19	cystatin F	Homo sapiens	35-39
22853447-0	2012	Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.	Glycine	103-106	solute carrier family 36 member 1	Homo sapiens	72-76
22853447-0	2012	Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.	Glycine	103-106	solute carrier family 36 member 1	Homo sapiens	78-85
22853447-4	2012	The aim of the present study is to investigate if other Gly-containing dipeptides interact with PAT1, and whether they can inhibit PAT1 mediated drug absorption, in vitro and in vivo.	Glycine	56-59	solute carrier family 36 member 1	Homo sapiens	96-100
22853447-9	2012	In Caco-2 cell monolayers, Gly-Gly, Gly-Sar, and Gly-Pro significantly inhibited the PAT1 mediated absorptive transepithelial transport of gaboxadol; however, when orally administered to rats, Gly-Gly, Gly-Sar, Gly-Pro, or Gly-Tyr did not alter the pharmacokinetic profile of gaboxadol.	Glycine	27-30	solute carrier family 36 member 1	Homo sapiens	85-89
22853447-9	2012	In Caco-2 cell monolayers, Gly-Gly, Gly-Sar, and Gly-Pro significantly inhibited the PAT1 mediated absorptive transepithelial transport of gaboxadol; however, when orally administered to rats, Gly-Gly, Gly-Sar, Gly-Pro, or Gly-Tyr did not alter the pharmacokinetic profile of gaboxadol.	Glycine	31-34	solute carrier family 36 member 1	Homo sapiens	85-89
22853447-9	2012	In Caco-2 cell monolayers, Gly-Gly, Gly-Sar, and Gly-Pro significantly inhibited the PAT1 mediated absorptive transepithelial transport of gaboxadol; however, when orally administered to rats, Gly-Gly, Gly-Sar, Gly-Pro, or Gly-Tyr did not alter the pharmacokinetic profile of gaboxadol.	Glycine	31-34	solute carrier family 36 member 1	Homo sapiens	85-89
22853447-9	2012	In Caco-2 cell monolayers, Gly-Gly, Gly-Sar, and Gly-Pro significantly inhibited the PAT1 mediated absorptive transepithelial transport of gaboxadol; however, when orally administered to rats, Gly-Gly, Gly-Sar, Gly-Pro, or Gly-Tyr did not alter the pharmacokinetic profile of gaboxadol.	Glycine	31-34	solute carrier family 36 member 1	Homo sapiens	85-89
22821884-1	2012	Costello syndrome is caused by HRAS germline mutations affecting Gly(12) or Gly(13) in &gt;90% of cases and these are associated with a relatively homogeneous phenotype.	Glycine	65-68	HRas proto-oncogene, GTPase	Homo sapiens	31-35
22821884-1	2012	Costello syndrome is caused by HRAS germline mutations affecting Gly(12) or Gly(13) in &gt;90% of cases and these are associated with a relatively homogeneous phenotype.	Glycine	76-79	HRas proto-oncogene, GTPase	Homo sapiens	31-35
22446032-4	2012	Alanine-glyoxylate aminotransferase, a peroxisomal enzyme in humans, converts glyoxylate into glycine, playing a central role in glyoxylate detoxification.	Glycine	94-101	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	0-35
22920190-5	2012	The inhibition by non-cytoxic doses of GLY of VSMCs migration was through its negative regulatory effects on phosphorylated ERK1/2, PI3K/AKT, and FAK.	Glycine	39-42	protein tyrosine kinase 2	Rattus norvegicus	146-149
22869748-2	2012	Interestingly, the Gly(717)-to-Arg mutation partially compensates the eEF2 functional loss resulting from diphthamide deficiency, possibly because the added +1 charge compensates for the loss of the +1 charge on diphthamide.	Glycine	19-22	eukaryotic translation elongation factor 2	Mus musculus	70-74
22681513-1	2012	Fish hemoglobins (Hbs) frequently contain glycine at site E14 while mammalian Hbs contain larger residues (e.g., alanine and serine).	Glycine	42-49	nuclear protein, coactivator of histone transcription	Homo sapiens	58-61
22681513-3	2012	The Ala(E14)Gly mutation increased k(ox) and hemin loss 3-fold and 45-fold, respectively.	Glycine	12-15	nuclear protein, coactivator of histone transcription	Homo sapiens	8-11
22681513-4	2012	Glycine at E14 creates a channel for solvent to enter the heme crevice, which enhances autoxidation and hemin loss rates.	Glycine	0-7	nuclear protein, coactivator of histone transcription	Homo sapiens	11-14
22681513-6	2012	Ala(E14)Gly promoted lipid oxidation in washed fish muscle more rapidly during iced storage compared to wild type Mb at pH 5.7.	Glycine	8-11	nuclear protein, coactivator of histone transcription	Homo sapiens	4-7
22681513-7	2012	This suggested that the rapid hemin loss from Ala(E14)Gly accelerated lipid oxidation.	Glycine	54-57	nuclear protein, coactivator of histone transcription	Homo sapiens	50-53
21812836-10	2012	The concomittant presence of low concentrations of histidine, alanine and either glycine or pyrrolidone-5-carboxylic acid (PCA) in the SC was associated with FLG mutations with 92% specificity.	Glycine	81-88	filaggrin	Homo sapiens	158-161
21544638-3	2012	MBL2 promoter polymorphisms at -550 (H/L), -221 (Y/X), +4 (P/Q), and exon polymorphisms at codon 52 (Arg/Cys), 54 (Gly/Asp, or A/B), and 57 (Gly/Glu) were investigated using polymerase chain reaction and restriction fragment length polymorphism.	Glycine	115-118	mannose binding lectin 2	Homo sapiens	0-4
21544638-3	2012	MBL2 promoter polymorphisms at -550 (H/L), -221 (Y/X), +4 (P/Q), and exon polymorphisms at codon 52 (Arg/Cys), 54 (Gly/Asp, or A/B), and 57 (Gly/Glu) were investigated using polymerase chain reaction and restriction fragment length polymorphism.	Glycine	141-144	mannose binding lectin 2	Homo sapiens	0-4
22695116-3	2012	In the central nervous system, extracellular glycine concentrations are regulated by two specific glycine transporters (GlyTs), GlyT1 and GlyT2.	Glycine	45-52	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	128-133
22695116-3	2012	In the central nervous system, extracellular glycine concentrations are regulated by two specific glycine transporters (GlyTs), GlyT1 and GlyT2.	Glycine	45-52	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	138-143
22695116-5	2012	We report that early postnatally (up to postnatal day P5) GlyT1 is the predominant transporter isoform responsible for a major fraction of the GlyT-mediated [(3)H]glycine uptake.	Glycine	163-170	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	58-63
22695116-7	2012	These alterations in the activities and expression profiles of the GlyTs suggest that the contributions of GlyT1 and GlyT2 to the regulation of extracellular glycine concentrations at glycinergic synapses changes during development.	Glycine	158-165	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	107-112
22695116-7	2012	These alterations in the activities and expression profiles of the GlyTs suggest that the contributions of GlyT1 and GlyT2 to the regulation of extracellular glycine concentrations at glycinergic synapses changes during development.	Glycine	158-165	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	117-122
23189554-1	2012	We have studied anti-tumor properties of bone marrow derived peptide Phe-Leu-Gly-Phe-Pro-Thr (MP-1) synthesized by classical methods.	Glycine	77-80	pitrilysin metallepetidase 1	Mus musculus	94-98
22022974-0	2012	Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist.	Glycine	134-141	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	65-78
19915682-1	2009	Inhibitory neurotransmitter receptors for glycine (GlyR) are heteropentameric chloride ion channels that are comprised of four functional subunits, alpha1-3 and beta and that facilitate fast-response, inhibitory neurotransmission in the mammalian brain and spinal cord.	Glycine	42-49	adrenoceptor alpha 1D	Homo sapiens	148-156
19247805-4	2009	One single nucleotide polymorphism (SNP) was detected in each gene (g. 149G&gt;T polymorphism in the porcine ANG gene, which resulted in an amino acid change from glycine to valine, g. 296A&gt;G polymorphism in the porcine RNASE1 gene and g. 389C&gt;T polymorphism in the porcine RNASE6 gene).	Glycine	163-170	angiogenin	Sus scrofa	109-112
29185083-2	2018	Ectopic expression of PCNA fused at either terminus with ubiquitin (Ub) lacking two C-terminal glycine residues induces translesion DNA synthesis which resembles synthesis mediated by PCNA monoubiquitination.	Glycine	95-102	proliferating cell nuclear antigen	Homo sapiens	22-26
19452450-1	2009	Serine racemase (SR) is responsible for the biosynthesis of D-serine (D-Ser), an endogenous co-agonist for the glycine (Gly)-binding site on N-methyl-D-aspartate (NMDA) receptors, from L-Ser in the brain.	Glycine	111-118	serine racemase	Mus musculus	0-15
19452450-1	2009	Serine racemase (SR) is responsible for the biosynthesis of D-serine (D-Ser), an endogenous co-agonist for the glycine (Gly)-binding site on N-methyl-D-aspartate (NMDA) receptors, from L-Ser in the brain.	Glycine	111-118	serine racemase	Mus musculus	17-19
19452450-1	2009	Serine racemase (SR) is responsible for the biosynthesis of D-serine (D-Ser), an endogenous co-agonist for the glycine (Gly)-binding site on N-methyl-D-aspartate (NMDA) receptors, from L-Ser in the brain.	Glycine	120-123	serine racemase	Mus musculus	0-15
19452450-1	2009	Serine racemase (SR) is responsible for the biosynthesis of D-serine (D-Ser), an endogenous co-agonist for the glycine (Gly)-binding site on N-methyl-D-aspartate (NMDA) receptors, from L-Ser in the brain.	Glycine	120-123	serine racemase	Mus musculus	17-19
22305237-5	2012	Sequence analysis of the GBE1 gene revealed compound heterozygosity for a previously described frameshift mutation (c.1239delT) and a novel missense mutation (c.1279G&gt;A) that is predicted to alter a conserved glycine residue.	Glycine	212-219	1,4-alpha-glucan branching enzyme 1	Homo sapiens	25-29
19452450-8	2009	Gly alone also significantly increased gene transactivation by the introduction of runt-related transcription factor-2 (Runx2) in COS7 cells transfected with NR1 and NR3A subunits, while D-Ser significantly prevented the increase by Gly without affecting the promoter activity of Runx2.	Glycine	0-3	runt related transcription factor 2	Mus musculus	120-125
22496447-0	2012	Invariant gly residue is important for alpha-defensin folding, dimerization, and function: a case study of the human neutrophil alpha-defensin HNP1.	Glycine	10-13	HNP1	Homo sapiens	143-147
29185083-3	2018	PCNA fused with Ub containing the C-terminal Gly residues at the C-terminus can be further polyubiquitinated in a Gly-dependent manner, which inhibits cell proliferation and induces ATR-dependent replication checkpoint.	Glycine	45-48	proliferating cell nuclear antigen	Homo sapiens	0-4
19452450-8	2009	Gly alone also significantly increased gene transactivation by the introduction of runt-related transcription factor-2 (Runx2) in COS7 cells transfected with NR1 and NR3A subunits, while D-Ser significantly prevented the increase by Gly without affecting the promoter activity of Runx2.	Glycine	0-3	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	158-161
19452450-8	2009	Gly alone also significantly increased gene transactivation by the introduction of runt-related transcription factor-2 (Runx2) in COS7 cells transfected with NR1 and NR3A subunits, while D-Ser significantly prevented the increase by Gly without affecting the promoter activity of Runx2.	Glycine	0-3	runt related transcription factor 2	Mus musculus	280-285
29185083-3	2018	PCNA fused with Ub containing the C-terminal Gly residues at the C-terminus can be further polyubiquitinated in a Gly-dependent manner, which inhibits cell proliferation and induces ATR-dependent replication checkpoint.	Glycine	114-117	proliferating cell nuclear antigen	Homo sapiens	0-4
22451665-3	2012	Utilizing biophysical and biochemical methods, we characterized two independent domains, Ala-35-Lys-124 and His-291-Gly-382, on the TRPM3 N terminus, responsible for interactions with the Ca(2+)-binding proteins calmodulin (CaM) and S100A1.	Glycine	116-119	transient receptor potential cation channel subfamily M member 3	Homo sapiens	132-137
30684342-2	2018	The paper is aimed at the study of the prevalence of the of TLR4 gene Gly and TLR7 gene Leu polymorphic alleles among patients with HIV/HCV-coinfection in general and with regard to gender, as well as to determine their role in the development of the infection.	Glycine	70-73	toll like receptor 4	Homo sapiens	60-64
22362770-6	2012	Alanine substitutions at positions Pro-113 Thr-115, Gly-117, Glu-122, and also Gln-109 enhanced the EphA2 receptor down-regulation and decreased p-ERK and p-AKT.	Glycine	52-55	eukaryotic translation initiation factor 2 alpha kinase 3	Homo sapiens	145-150
21305139-4	2009	The ferric ion ligands have been identified as glutamates 7, 8 and 9 in the 18 amino acid peptide glycine-extended gastrin.	Glycine	98-105	gastrin	Homo sapiens	115-122
19545238-1	2009	PH1 (primary hyperoxaluria type 1) is a severe inborn disorder of glyoxylate metabolism caused by a functional deficiency of the peroxisomal enzyme AGXT (alanine-glyoxylate aminotransferase), which converts glyoxylate into glycine using L-alanine as the amino-group donor.	Glycine	223-230	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	0-3
19545238-1	2009	PH1 (primary hyperoxaluria type 1) is a severe inborn disorder of glyoxylate metabolism caused by a functional deficiency of the peroxisomal enzyme AGXT (alanine-glyoxylate aminotransferase), which converts glyoxylate into glycine using L-alanine as the amino-group donor.	Glycine	223-230	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	5-33
19545238-1	2009	PH1 (primary hyperoxaluria type 1) is a severe inborn disorder of glyoxylate metabolism caused by a functional deficiency of the peroxisomal enzyme AGXT (alanine-glyoxylate aminotransferase), which converts glyoxylate into glycine using L-alanine as the amino-group donor.	Glycine	223-230	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	154-189
22430737-4	2012	We found that Trx1 is expressed in a redox-active form at the surface of HUVEC and acts as an inhibitor of complement deposition in a manner dependent on its Cys-Gly-Pro-Cys active site.	Glycine	162-165	thioredoxin	Homo sapiens	14-18
30684342-5	2018	RESULTS: Results and conclusion:The study found thatthe prevalence of the TLR4 gene Gly polymorphic allele among patients with HIV/HCV-coinfection, HIV-monoinfection and chronic hepatitis C accounted for 23.1 %, 14.4 % and 14.5 %, respectively, which is significantly higher than the similar index in controls - 3.3 %.	Glycine	84-87	toll like receptor 4	Homo sapiens	74-78
22496565-3	2012	Here we report that sustained incubation with the endocannabinoid anandamide (AEA) substantially increased the amplitude of glycine-activated current in both rat cultured spinal neurons and in HEK-293 cells expressing human alpha1, rat alpha2 and alpha3 GlyRs.	Glycine	124-131	adrenoceptor alpha 1D	Homo sapiens	224-242
29170475-4	2017	In this study, we demonstrate that the BLT2 SNP (rs1950504, Asp196Gly), a Gly-196 variant of BLT2 (BLT2 D196G), causes enhanced cell motility under low-dose stimulation of its ligands.	Glycine	66-69	leukotriene B4 receptor 2	Homo sapiens	39-43
22639647-8	2012	Transgenic lines bearing all three transgenic enzyme activities were identified and some with higher CAT activity showed higher dry weight, higher photosynthetic rates, and changes in glycine/serine ratio compared to the wild type.	Glycine	184-191	catalase 2	Arabidopsis thaliana	101-104
29170475-4	2017	In this study, we demonstrate that the BLT2 SNP (rs1950504, Asp196Gly), a Gly-196 variant of BLT2 (BLT2 D196G), causes enhanced cell motility under low-dose stimulation of its ligands.	Glycine	66-69	leukotriene B4 receptor 2	Homo sapiens	93-97
22194595-8	2012	Surprisingly, only one of the four conserved intramembrane glycine residues significantly affects the secondary structure of the Bri2 TMD and thereby its intramembrane cleavage.	Glycine	59-66	integral membrane protein 2B	Homo sapiens	129-133
19282154-1	2009	The specific glycine transporter 1 (GlyT1) inhibitor, SSR504734, is highly effective in enhancing N-methyl-D-aspartate receptor (NMDAR) function by elevating the availability of the NMDAR co-agonist, glycine, in the vicinity of NMDAR-containing glutamatergic synapses.	Glycine	13-20	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	36-41
19282154-1	2009	The specific glycine transporter 1 (GlyT1) inhibitor, SSR504734, is highly effective in enhancing N-methyl-D-aspartate receptor (NMDAR) function by elevating the availability of the NMDAR co-agonist, glycine, in the vicinity of NMDAR-containing glutamatergic synapses.	Glycine	13-20	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	98-127
19282154-1	2009	The specific glycine transporter 1 (GlyT1) inhibitor, SSR504734, is highly effective in enhancing N-methyl-D-aspartate receptor (NMDAR) function by elevating the availability of the NMDAR co-agonist, glycine, in the vicinity of NMDAR-containing glutamatergic synapses.	Glycine	13-20	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	129-134
29170475-4	2017	In this study, we demonstrate that the BLT2 SNP (rs1950504, Asp196Gly), a Gly-196 variant of BLT2 (BLT2 D196G), causes enhanced cell motility under low-dose stimulation of its ligands.	Glycine	66-69	leukotriene B4 receptor 2	Homo sapiens	93-97
19282154-1	2009	The specific glycine transporter 1 (GlyT1) inhibitor, SSR504734, is highly effective in enhancing N-methyl-D-aspartate receptor (NMDAR) function by elevating the availability of the NMDAR co-agonist, glycine, in the vicinity of NMDAR-containing glutamatergic synapses.	Glycine	13-20	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	182-187
28840369-2	2017	We have designed, and synthesized novel 1,3,4 oxadiazole with glycine/alanine hybrids as HDAC8-specific inhibitors and preliminary evaluation has indicated that 1,3,4 oxadiazole with alanine hybrid [(R)-2-amino-N-((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)propanamide (10b)] to be a potent HDAC8 inhibitor.	Glycine	62-69	histone deacetylase 8	Homo sapiens	89-94
19282154-1	2009	The specific glycine transporter 1 (GlyT1) inhibitor, SSR504734, is highly effective in enhancing N-methyl-D-aspartate receptor (NMDAR) function by elevating the availability of the NMDAR co-agonist, glycine, in the vicinity of NMDAR-containing glutamatergic synapses.	Glycine	13-20	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	182-187
19502485-1	2009	Fertilized mouse eggs regulate their size principally by accumulating glycine as an intracellular osmolyte using the GLYT1 (SLC6A9) transporter, a mechanism of cell volume homeostasis apparently unique to early embryos before the morula stage.	Glycine	70-77	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	117-122
22179617-1	2012	Osteopontin (OPN) is a multifunctional phosphorylated protein containing the integrin binding sequence Arg-Gly-Asp through which it interacts with several integrin receptors, such as the alpha(V)beta(3)-integrin.	Glycine	107-110	secreted phosphoprotein 1	Homo sapiens	0-11
22179617-1	2012	Osteopontin (OPN) is a multifunctional phosphorylated protein containing the integrin binding sequence Arg-Gly-Asp through which it interacts with several integrin receptors, such as the alpha(V)beta(3)-integrin.	Glycine	107-110	secreted phosphoprotein 1	Homo sapiens	13-16
28722183-3	2017	In this context our finding of an unusual motif of glycine-rich PGII -like helices in the structure of the acetophenone carboxylase core complex is of relevance.	Glycine	51-58	decorin	Homo sapiens	64-68
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	167-170	interleukin 24	Homo sapiens	64-69
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	167-170	interleukin 24	Homo sapiens	92-97
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	167-170	interleukin 24	Homo sapiens	98-103
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	167-170	interleukin 24	Homo sapiens	233-238
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	167-170	interleukin 24	Homo sapiens	98-103
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	183-190	interleukin 24	Homo sapiens	64-69
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	183-190	interleukin 24	Homo sapiens	92-97
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	183-190	interleukin 24	Homo sapiens	98-103
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	183-190	interleukin 24	Homo sapiens	233-238
22248086-3	2012	This rout was exploited to construct a tumor-targeting gene RGD-IL-24 which can express RGD-MDA-7/IL-24 protein that includes the cell adhesive sequence (164)Arg-(165)Gly-(166)Asp (A Glycine residue was inserted into the recombinant MDA-7/IL-24 between Arg164 and Asp165 to form a RGD motif).	Glycine	183-190	interleukin 24	Homo sapiens	98-103
22044943-8	2012	We show that high-glycine induces a form of chemical long-term potentiation (chemLTP) in CGCs characterized by an increase in AMPAR-mEPSC frequency but not amplitude.	Glycine	18-25	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	126-131
19502485-1	2009	Fertilized mouse eggs regulate their size principally by accumulating glycine as an intracellular osmolyte using the GLYT1 (SLC6A9) transporter, a mechanism of cell volume homeostasis apparently unique to early embryos before the morula stage.	Glycine	70-77	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	124-130
19396436-6	2009	RESULTS: The DRD2 Taq1A allele frequencies were A141.7 (A1) and 58.3% (A2), and the DRD3 Ser9Gly allele frequencies were 68.3 (Ser) and 31.7% (Gly).	Glycine	93-96	dopamine receptor D3	Homo sapiens	84-88
19398000-2	2009	In fibrillar collagens, MMP-1, MMP-8, and MMP-13 cleave a specific glycine-isoleucine or glycine-leucine bond, despite the presence of this sequence in other parts of the protein.	Glycine	67-74	matrix metallopeptidase 1	Homo sapiens	24-29
19398000-2	2009	In fibrillar collagens, MMP-1, MMP-8, and MMP-13 cleave a specific glycine-isoleucine or glycine-leucine bond, despite the presence of this sequence in other parts of the protein.	Glycine	67-74	matrix metallopeptidase 8	Homo sapiens	31-36
19398000-2	2009	In fibrillar collagens, MMP-1, MMP-8, and MMP-13 cleave a specific glycine-isoleucine or glycine-leucine bond, despite the presence of this sequence in other parts of the protein.	Glycine	89-96	matrix metallopeptidase 1	Homo sapiens	24-29
19398000-2	2009	In fibrillar collagens, MMP-1, MMP-8, and MMP-13 cleave a specific glycine-isoleucine or glycine-leucine bond, despite the presence of this sequence in other parts of the protein.	Glycine	89-96	matrix metallopeptidase 8	Homo sapiens	31-36
29204107-2	2017	The CD13-targeting moiety NGR was synthesized and cyclized by native chemical ligation (NCL) instead of disulfide bridging, leading to a cyclic peptide backbone: cyclo(Cys-Asn-Gly-Arg-Gly) (coNGR).	Glycine	176-179	alanyl (membrane) aminopeptidase	Mus musculus	4-8
22133759-7	2012	Furthermore, the effect of lidocaine and its metabolites on glycine-induced currents were investigated in GlyT1-expressing Xenopus laevis oocytes.	Glycine	60-67	solute carrier family 6 member 9 L homeolog	Xenopus laevis	106-111
22133759-12	2012	CONCLUSIONS: Although lidocaine does not function directly on GlyT1, its metabolites MEGX and N-ethylglycine [corrected] were shown to inhibit GlyT1-mediated glycine uptake by at least two different mechanisms.	Glycine	101-108	solute carrier family 6 member 9 L homeolog	Xenopus laevis	143-148
29204107-2	2017	The CD13-targeting moiety NGR was synthesized and cyclized by native chemical ligation (NCL) instead of disulfide bridging, leading to a cyclic peptide backbone: cyclo(Cys-Asn-Gly-Arg-Gly) (coNGR).	Glycine	184-187	alanyl (membrane) aminopeptidase	Mus musculus	4-8
29018191-4	2017	Here we show that astrocytes in the mouse caudal medullary brainstem can synthesize, store, and release D-serine, an agonist for the glycine-binding site of the NMDAR, in response to elevated CO2 levels.	Glycine	133-140	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	161-166
21660517-0	2012	Treatment by oral creatine, L-arginine and L-glycine in six severely affected patients with creatine transporter defect.	Glycine	43-52	solute carrier family 25 member 1	Homo sapiens	92-112
22119847-10	2012	We succeeded to solve the crystal structure of a complex composed of a heterodimer of EB1 and EB3 C-termini together with the CAP-Gly domain of p150(glued).	Glycine	130-133	microtubule associated protein RP/EB family member 3	Homo sapiens	94-97
28545165-7	2017	H3F3A glycine hotspot mutations were the most frequently detected mutations (96%) in the 52 GCTBs by NGS.	Glycine	6-13	H3.3 histone A	Homo sapiens	0-5
22719251-4	2012	Structural comparison revealed a conserved glycine-serine-rich (GSR) ClfB binding motif (GSSGXGXXG) within the ligands, which was also found in other human proteins such as Engrailed protein, TCF20 and Dermokine proteins.	Glycine	43-50	transcription factor 20	Homo sapiens	192-197
28961169-1	2017	Human thioredoxin (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-, which is induced by biological stress due to oxidative damage, metabolic dysfunction, chemicals, infection/inflammation, irradiation, or hypoxia/ischemia-reperfusion.	Glycine	94-97	thioredoxin	Homo sapiens	6-17
22041185-1	2011	Glycine and/or D-serine are obligatory coagonists of the N-methyl-D-aspartate receptor (NMDAR).	Glycine	0-7	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	57-86
28961169-1	2017	Human thioredoxin (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-, which is induced by biological stress due to oxidative damage, metabolic dysfunction, chemicals, infection/inflammation, irradiation, or hypoxia/ischemia-reperfusion.	Glycine	94-97	thioredoxin	Homo sapiens	19-22
22041185-1	2011	Glycine and/or D-serine are obligatory coagonists of the N-methyl-D-aspartate receptor (NMDAR).	Glycine	0-7	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	88-93
28973773-5	2017	Our gene model, MaSp1, is 1037-bp long, with 68% GC content, and its amino acid sequence is characterized by poly-alanine-glycine motifs, which represent the repetitive codon consensus.	Glycine	122-129	MBL associated serine protease 1	Homo sapiens	16-21
21822533-5	2011	siRNA-mediated reduction of fibronectin and interference in the liaison between fibronectin and integrins by the Arg-Gly-Asp-Ser (RGDS) peptide increased aggrecan expression, and decreased versican expression by TGF-beta1 stimulation.	Glycine	117-120	fibronectin 1	Mus musculus	80-91
21882401-12	2004	A DOTA-Gly-benzoyl group was added to the C-terminus to form DOTA-Gly-benzoyl-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 (RM1).	Glycine	7-10	GCY	Homo sapiens	108-111
28916765-1	2017	The alanine:glyoxylate aminotransferase (AGT), a hepatocyte-specific pyridoxal-5"-phosphate (PLP) dependent enzyme, transaminates L-alanine and glyoxylate to glycine and pyruvate, thus detoxifying glyoxylate and preventing pathological oxalate precipitation in tissues.	Glycine	158-165	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	4-39
28916765-1	2017	The alanine:glyoxylate aminotransferase (AGT), a hepatocyte-specific pyridoxal-5"-phosphate (PLP) dependent enzyme, transaminates L-alanine and glyoxylate to glycine and pyruvate, thus detoxifying glyoxylate and preventing pathological oxalate precipitation in tissues.	Glycine	158-165	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	41-44
28955208-1	2017	The alpha9 and alpha10 nicotinic acetylcholine receptor (nAChR) subunits are likely to be the evolutionary precursors to the entire cys-loop superfamily of ligand-gated ion channels, which includes acetylcholine, GABA, glycine and serotonin ionotropic receptors.	Glycine	219-226	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	57-62
21690089-4	2011	We have used cysteine-scanning mutagenesis to determine the contribution of residues Glu(52)-Gly(96) to human P2X1 receptor properties.	Glycine	93-96	purinergic receptor P2X 1	Homo sapiens	110-123
21847098-4	2011	PIKE-L directly interacts with both GluA2 and GRIP1 and forms a tertiary complex upon glycine-induced NMDA receptor activation.	Glycine	86-93	glutamate receptor interacting protein 1	Homo sapiens	46-51
28819560-2	2017	With computational prediction algorithms and structure-based drug design, we identified peptides containing the Gly-Lys-Gly-Glu-Gly-Glu-Gly-Lys-Gly sequence (peptide H1), which strongly interacts with uPAR.	Glycine	112-115	plasminogen activator, urokinase receptor	Homo sapiens	201-205
21807943-2	2011	CB mutations cause X-linked mental retardation due to defective clustering of gephyrin, a postsynaptic protein associated with both glycine and GABA(A) receptors.	Glycine	132-139	gephyrin	Homo sapiens	78-86
28819560-2	2017	With computational prediction algorithms and structure-based drug design, we identified peptides containing the Gly-Lys-Gly-Glu-Gly-Glu-Gly-Lys-Gly sequence (peptide H1), which strongly interacts with uPAR.	Glycine	120-123	plasminogen activator, urokinase receptor	Homo sapiens	201-205
21595009-2	2011	A glycine-to-serine polymorphism at codon 9 of the dopamine D3 receptor gene (DRD3), rs6280, has been widely studied for its association with SZ, but with conflicting results.	Glycine	2-9	dopamine receptor D3	Homo sapiens	78-82
28819560-2	2017	With computational prediction algorithms and structure-based drug design, we identified peptides containing the Gly-Lys-Gly-Glu-Gly-Glu-Gly-Lys-Gly sequence (peptide H1), which strongly interacts with uPAR.	Glycine	120-123	plasminogen activator, urokinase receptor	Homo sapiens	201-205
21584310-6	2011	PAD4 citrullinates the Arg-Gly repeat region of RPS2, which is also an established site for Arg methylation by protein arginine methyltransferase 3 (PRMT3).	Glycine	27-30	peptidyl arginine deiminase 4	Homo sapiens	0-4
28819560-2	2017	With computational prediction algorithms and structure-based drug design, we identified peptides containing the Gly-Lys-Gly-Glu-Gly-Glu-Gly-Lys-Gly sequence (peptide H1), which strongly interacts with uPAR.	Glycine	120-123	plasminogen activator, urokinase receptor	Homo sapiens	201-205
27589375-1	2017	Mouse embryos employ a unique mechanism of cell volume regulation in which glycine is imported via the GLYT1 transporter to regulate intracellular osmotic pressure.	Glycine	75-82	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	103-108
21396938-3	2011	Sequence alignments of GSL-binding proteins against the GBM of alpha-synuclein allowed the establishment of a consensus GBM sequence defined as K/H/R/-X(1-4)-Y/F-X(4-5)-K/H/R, where at least one of the X(1-4) residues is glycine.	Glycine	221-228	synuclein alpha	Homo sapiens	63-78
21563332-12	2004	A DOTA-Gly-benzoyl group was added to the C-terminus to form DOTA-Gly-benzoyl-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 (RM1).	Glycine	7-10	GCY	Homo sapiens	108-111
28614652-6	2017	Interestingly, three of the four mapped sites contain a glycine residue (G36, G41, and G51) that is likely to be involved in a beta-turn in the fibril, whereupon cutting would lead to solvent exposure of internal residues and allow further proteolysis.	Glycine	56-63	protein phosphatase 2 regulatory subunit B''gamma	Homo sapiens	78-81
21371789-1	2011	Serine hydroxymethyltransferase (SHMT), a ubiquitous representative of the family of fold-type I, pyridoxal 5"-phosphate (PLP) dependent enzymes, catalyzes the reversible conversion of tetrahydrofolate (H4PteGlu) and serine to 5,10-CH2-H4PteGlu and glycine.	Glycine	249-256	serine hydroxymethyltransferase 1	Homo sapiens	0-31
21371789-1	2011	Serine hydroxymethyltransferase (SHMT), a ubiquitous representative of the family of fold-type I, pyridoxal 5"-phosphate (PLP) dependent enzymes, catalyzes the reversible conversion of tetrahydrofolate (H4PteGlu) and serine to 5,10-CH2-H4PteGlu and glycine.	Glycine	249-256	serine hydroxymethyltransferase 1	Homo sapiens	33-37
28447171-1	2017	A recurrent glycine-to-arginine/valine alteration at codon 34 (G34R/V) within H3F3A, a gene that encodes the replication-independent histone variant H3.3, reportedly occurs exclusively in pediatric glioblastomas.	Glycine	12-19	H3.3 histone A	Homo sapiens	78-83
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	9-16	solute carrier family 6 member 5	Rattus norvegicus	248-253
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	71-78	solute carrier family 6 member 5	Rattus norvegicus	248-253
28634406-2	2017	Previous reports associated MIH with a decreased expression of the Cl- extruder KCC2 in the superficial dorsal horn (SDH) of the spinal cord, weakening spinal GABAA/glycine-mediated postsynaptic inhibition.	Glycine	165-172	solute carrier family 12 member 5	Rattus norvegicus	80-84
21525276-5	2011	Intra-NAc treatment with the selective mu-opioid receptor agonist [D-Ala(2),N-MePhe(4),Gly(5)-ol]enkephalin (DAMGO) (0.1-10 ng) and the mu-opioid receptor antagonist Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH(2) (CTAP) (0.3-3 mug) increased and decreased social play, respectively.	Glycine	87-90	proenkephalin	Rattus norvegicus	97-107
28594869-1	2017	Glycyl-tRNA synthetase (GARS; OMIM 600287) is one of thirty-seven tRNA-synthetase genes that catalyses the synthesis of glycyl-tRNA, which is required to insert glycine into proteins within the cytosol and mitochondria.	Glycine	161-168	glycyl-tRNA synthetase 1	Homo sapiens	0-22
21548211-1	2011	OBJECTIVE: To investigate the binding characteristics of interleukin 11 (IL-11) analogue-cyclic nonapeptide c(Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys) NH2 C30H54N16O10S2, c(CGRRAGGSC), and human prostate cancer PC-3 cells.	Glycine	114-117	interleukin 11	Homo sapiens	57-71
21548211-1	2011	OBJECTIVE: To investigate the binding characteristics of interleukin 11 (IL-11) analogue-cyclic nonapeptide c(Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys) NH2 C30H54N16O10S2, c(CGRRAGGSC), and human prostate cancer PC-3 cells.	Glycine	114-117	interleukin 11	Homo sapiens	73-78
21548211-1	2011	OBJECTIVE: To investigate the binding characteristics of interleukin 11 (IL-11) analogue-cyclic nonapeptide c(Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys) NH2 C30H54N16O10S2, c(CGRRAGGSC), and human prostate cancer PC-3 cells.	Glycine	130-133	interleukin 11	Homo sapiens	57-71
21548211-1	2011	OBJECTIVE: To investigate the binding characteristics of interleukin 11 (IL-11) analogue-cyclic nonapeptide c(Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys) NH2 C30H54N16O10S2, c(CGRRAGGSC), and human prostate cancer PC-3 cells.	Glycine	130-133	interleukin 11	Homo sapiens	73-78
21548211-1	2011	OBJECTIVE: To investigate the binding characteristics of interleukin 11 (IL-11) analogue-cyclic nonapeptide c(Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys) NH2 C30H54N16O10S2, c(CGRRAGGSC), and human prostate cancer PC-3 cells.	Glycine	130-133	interleukin 11	Homo sapiens	57-71
21548211-1	2011	OBJECTIVE: To investigate the binding characteristics of interleukin 11 (IL-11) analogue-cyclic nonapeptide c(Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys) NH2 C30H54N16O10S2, c(CGRRAGGSC), and human prostate cancer PC-3 cells.	Glycine	130-133	interleukin 11	Homo sapiens	73-78
19332109-1	2009	Converging evidence from pharmacological and molecular studies has led to the suggestion that inhibition of glycine transporter 1 (GlyT1) constitutes an effective means to boost N-methyl-d-aspartate receptor (NMDAR) activity by increasing the extra-cellular concentration of glycine in the vicinity of glutamatergic synapses.	Glycine	108-115	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	209-214
28594869-1	2017	Glycyl-tRNA synthetase (GARS; OMIM 600287) is one of thirty-seven tRNA-synthetase genes that catalyses the synthesis of glycyl-tRNA, which is required to insert glycine into proteins within the cytosol and mitochondria.	Glycine	161-168	glycyl-tRNA synthetase 1	Homo sapiens	24-28
21185916-0	2011	The possible additional role of the cystic fibrosis transmembrane regulator to motoneuron inhibition produced by glycine effects.	Glycine	113-120	CF transmembrane conductance regulator	Rattus norvegicus	36-75
28315445-4	2017	The presence of an apical side pH of 6.5 (mimicking the intestinal acidic microclimate) and of Gly-Sar (a high affinity competitive inhibitor and substrate for PepT1) were tested on the transepithelial apical to basolateral (A to B) transport of [3H]-IPP and [3H]-LKP across filter-grown Caco-2 monolayers in vitro and rat jejunal mucosae ex vivo.	Glycine	95-98	solute carrier family 15 member 1	Rattus norvegicus	160-165
21279630-3	2011	Among these, it was found that insertion of oxygen atoms occurred at histidine for HG and HGG, and both histidine and glycine for GH, GHG, and GGH.	Glycine	118-125	gamma-glutamyl hydrolase	Homo sapiens	143-146
19400947-3	2009	HLS is caused by a substitution of aspartic acid by glycine in the HYLS1 protein, whose function was previously unknown.	Glycine	52-59	HYLS1 centriolar and ciliogenesis associated	Homo sapiens	0-3
19400947-3	2009	HLS is caused by a substitution of aspartic acid by glycine in the HYLS1 protein, whose function was previously unknown.	Glycine	52-59	HYLS1 centriolar and ciliogenesis associated	Homo sapiens	67-72
28698298-1	2017	The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5" cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine-tyrosine-phenylalanine domain) proteins 1 and 2 (GIGYF1/2).	Glycine	254-261	eukaryotic translation initiation factor 4E family member 2	Homo sapiens	30-34
28698298-1	2017	The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5" cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine-tyrosine-phenylalanine domain) proteins 1 and 2 (GIGYF1/2).	Glycine	254-261	growth factor receptor bound protein 10	Homo sapiens	231-236
21379321-7	2011	The strongest candidate variant causes a glycine to arginine substitution in a highly conserved region of the metalloproteinase ADAMTS10.	Glycine	41-48	ADAM metallopeptidase with thrombospondin type 1 motif 10	Canis lupus familiaris	128-136
28542346-10	2017	A comparison of the clinical manifestations caused by different types of mutations in COL4A5 suggested that nonsense mutations and glycine substitution by an acidic amino acid are more severe than the other missense mutations.	Glycine	131-138	collagen type IV alpha 5 chain	Homo sapiens	86-92
20641535-0	2004	(111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1).	Glycine	13-16	GCY	Homo sapiens	55-58
20641535-12	2004	DOTA-Gly-benzoyl group was added to the C-terminus to form DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 (RM1).	Glycine	4-8	GCY	Homo sapiens	106-109
20641535-12	2004	DOTA-Gly-benzoyl group was added to the C-terminus to form DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 (RM1).	Glycine	5-8	GCY	Homo sapiens	106-109
18789468-3	2009	Fibrillin-1 contains the Arg-Gly-Asp (RGD) motif, which may allow binding to RGD-recognizing integrins.	Glycine	29-32	fibrillin 1	Homo sapiens	0-11
20641344-11	2004	The tumor homing peptide cyclo(Cys-Asn-Gly-Arg-Cys)-Gly-Lys (cNGR) contains the Asn-Gly-Arg (NGR) motif that binds to APN (11).	Glycine	39-42	alanyl (membrane) aminopeptidase	Mus musculus	118-121
20641344-11	2004	The tumor homing peptide cyclo(Cys-Asn-Gly-Arg-Cys)-Gly-Lys (cNGR) contains the Asn-Gly-Arg (NGR) motif that binds to APN (11).	Glycine	52-55	alanyl (membrane) aminopeptidase	Mus musculus	118-121
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	328-357
21628896-5	2011	In regards to the activity of U II, it is determined that the hydrophobic Phe-6 plays a more critical role than Gly-8 or Arg-10.	Glycine	112-115	urotensin 2	Homo sapiens	30-34
28515681-3	2017	In this study, we demonstrated the expression of a lncRNA cluster, namely maternally expressed gene 3 (Meg3), retrotransposon-like gene 1-anti-sense (Rtl1-AS), Meg8 and Meg9, which is located in the maternally imprinted Dlk1-Dio3 region on mouse chromosome 12qF1, in primary cortical neurons following glycine stimulation in an N-Methyl-D-aspartate receptor (NMDAR)-dependent manner.	Glycine	302-309	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	359-364
19452600-3	2009	Here, we have used site-directed mutagenesis to create five proline to glycine variants in the naturally amyloidogenic protein beta2-microglobulin (beta2m).	Glycine	71-78	beta-2-microglobulin	Homo sapiens	127-146
28515681-6	2017	Further analysis revealed that Meg3 loss of function blocked the glycine-induced increase of the GluA1 subunit of AMPA receptors on the plasma membrane, a major hallmark of LTP.	Glycine	65-72	maternally expressed 3	Mus musculus	31-35
19452600-3	2009	Here, we have used site-directed mutagenesis to create five proline to glycine variants in the naturally amyloidogenic protein beta2-microglobulin (beta2m).	Glycine	71-78	beta-2-microglobulin	Homo sapiens	148-154
28202572-11	2017	Together these findings indicate activity-dependent and synapse-specific regulation of the coagonist binding site within spinal locomotor networks, illustrating the importance of NMDAR regulation in shaping motor output.NEW &amp; NOTEWORTHY We provide evidence that NMDARs within murine spinal locomotor networks determine the frequency and amplitude of ongoing locomotor-related activity in vitro and that NMDARs are regulated by d-serine and glycine in a synapse-specific and activity-dependent manner.	Glycine	444-451	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	179-184
19265520-0	2009	The glycine brace: a component of Rab, Rho, and Ran GTPases associated with hinge regions of guanine- and phosphate-binding loops.	Glycine	4-11	RAN, member RAS oncogene family	Homo sapiens	48-51
19265520-3	2009	RESULTS: Bayesian analysis of divergent patterns within a multiple alignment of Ras-like GTPase sequences identifies a structural component, termed here the glycine brace, as the feature that most distinguishes Rab, Rho/Rac, Ran and (to some degree) Ras family GTPases from other Ras-like GTPases.	Glycine	157-164	RAN, member RAS oncogene family	Homo sapiens	225-228
18824844-8	2009	The analysis of mRNA expressions of Th1 (t-bet, TNF-alpha, IL-1beta) and Th2 (gata-3, IL-4, IL-10) cytokines showed a Th1-polarized response in Gly-AKI rats that was aggravated with the anti-HGF treatment.	Glycine	144-147	interleukin 10	Rattus norvegicus	92-97
21691091-0	2011	Integrin signaling modulates AQP2 trafficking via Arg-Gly-Asp (RGD) motif.	Glycine	54-57	aquaporin 2	Homo sapiens	29-33
21361869-1	2011	D-amino acid oxidase (DAAO) catalyzes the oxidative metabolism of D-amino acids including D-serine, a full agonist at the allosteric glycine binding site of the NMDA receptor.	Glycine	133-140	D-amino acid oxidase	Homo sapiens	0-20
21361869-1	2011	D-amino acid oxidase (DAAO) catalyzes the oxidative metabolism of D-amino acids including D-serine, a full agonist at the allosteric glycine binding site of the NMDA receptor.	Glycine	133-140	D-amino acid oxidase	Homo sapiens	22-26
28425994-8	2017	Notably, Kras-driven mouse models of pancreatic and intestinal cancers were less responsive to depletion of serine and glycine, reflecting an ability of activated Kras to increase the expression of enzymes that are part of the serine synthesis pathway and thus promote de novo serine synthesis.	Glycine	119-126	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	9-13
21081141-4	2011	The VvRtxA C-terminal Gly-Asp (GD) repeat-containing region, which has been implicated for calcium binding and target cell recognition, was chosen as an antigen to screen a scFv phage display library.	Glycine	22-25	RTX toxin RtxA	Vibrio vulnificus	4-10
21870221-7	2011	As an alternative approach, we have utilized a glycine-to-serine mutation in the switch 1 region of Galpha subunits that prevents RGS binding.	Glycine	47-54	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	100-106
20939853-10	2011	The secretion of the inflammatory proteins IL-6, monocyte chemotactic protein-1/chemokine ligand 2 and macrophage inflammatory protein-1alpha/chemokine ligand 3 were also significantly decreased by glycine pretreatment.	Glycine	198-205	C-C motif chemokine ligand 2	Homo sapiens	49-79
20939853-10	2011	The secretion of the inflammatory proteins IL-6, monocyte chemotactic protein-1/chemokine ligand 2 and macrophage inflammatory protein-1alpha/chemokine ligand 3 were also significantly decreased by glycine pretreatment.	Glycine	198-205	C-C motif chemokine ligand 3	Homo sapiens	80-141
20093729-1	2009	The N-terminal regions of annexins A7 (synexin) and A11 consist of an extended series of short sequence repeats rich in tyrosine, proline, and glycine that provide binding sites for other proteins that may be recruited to membranes by the annexins and that may modulate the calcium and membrane binding activities of the annexin core domains.	Glycine	143-150	annexin A7	Homo sapiens	39-46
18976908-1	2008	Oxazole containing glycine and oximinobutyric acid derivatives were synthesized as PPARalpha agonists by incorporating polymethylene spacer as a replacement of commonly used phenylene group that connects the acidic head with lipophilic tail.	Glycine	19-26	peroxisome proliferator activated receptor alpha	Homo sapiens	83-92
28425994-8	2017	Notably, Kras-driven mouse models of pancreatic and intestinal cancers were less responsive to depletion of serine and glycine, reflecting an ability of activated Kras to increase the expression of enzymes that are part of the serine synthesis pathway and thus promote de novo serine synthesis.	Glycine	119-126	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	163-167
28424332-6	2017	We also report the discovery of a highly recurrent de novo intronic mutation in COL6A1 that results in a dominantly acting splice-gain event, disrupting the critical glycine repeat motif of the triple helical domain.	Glycine	166-173	collagen type VI alpha 1 chain	Homo sapiens	80-86
19030549-1	2008	This work reports the synthesis of protected Gly-Arg-Gly-Asp-Ser functionalised hydrogels, which are deprotected (and activated for cell adhesion) by reaction with glutathione-S-transferase.	Glycine	45-48	glutathione S-transferase kappa 1	Homo sapiens	164-189
18438722-5	2008	Of 38 ESCC, the immunoreactivities of gastrin, glycine-extended gastrin and progastrin were observed in 13.2% (5/38), 7.9% (3/38) and 23.68% (9/38) cases.	Glycine	47-54	gastrin	Homo sapiens	64-71
21474970-7	2011	In taurocholate pancreatitis, glycine additionally diminished pancreatic cytokines and MPO activity, as well as serum lipase and amylase levels.	Glycine	30-37	myeloperoxidase	Rattus norvegicus	87-90
21474970-7	2011	In taurocholate pancreatitis, glycine additionally diminished pancreatic cytokines and MPO activity, as well as serum lipase and amylase levels.	Glycine	30-37	lipase G, endothelial type	Rattus norvegicus	118-124
22132110-4	2011	Neutralizing antibody to integrin alphavbeta3 and an integrin-binding Arg-Gly-Asp (RGD) peptide blocked thyroid hormone-induced PCNA expression.	Glycine	74-77	proliferating cell nuclear antigen	Homo sapiens	128-132
18438722-7	2008	In positive cases for gastrin or glycine-extended gastrin, the scores of positive tumor cell numbers were at a lower density (&lt;10/abundant-distributed field).	Glycine	33-40	gastrin	Homo sapiens	50-57
28057537-3	2017	Na+-K+-2Cl- co-transporter 1 (NKCC1) and K+-Cl- co-transporter 2 (KCC2) generally dictate the tone of GABA/glycine inhibition by regulating intracellular chloride concentrations.	Glycine	107-114	solute carrier family 12 member 2	Homo sapiens	0-28
18553216-7	2008	Additionally, inhibition of a Cl(-) uptake transporter NKCC1 with bumetanid effectively eliminated glycine-evoked a weak depolarization in rods, suggesting that NKCC1 maintains a high Cl(-) level in rods, which causes to depolarize in responding to glycine input.	Glycine	99-106	solute carrier family 12 member 2	Homo sapiens	55-60
18553216-7	2008	Additionally, inhibition of a Cl(-) uptake transporter NKCC1 with bumetanid effectively eliminated glycine-evoked a weak depolarization in rods, suggesting that NKCC1 maintains a high Cl(-) level in rods, which causes to depolarize in responding to glycine input.	Glycine	99-106	solute carrier family 12 member 2	Homo sapiens	161-166
18553216-7	2008	Additionally, inhibition of a Cl(-) uptake transporter NKCC1 with bumetanid effectively eliminated glycine-evoked a weak depolarization in rods, suggesting that NKCC1 maintains a high Cl(-) level in rods, which causes to depolarize in responding to glycine input.	Glycine	249-256	solute carrier family 12 member 2	Homo sapiens	55-60
18553216-7	2008	Additionally, inhibition of a Cl(-) uptake transporter NKCC1 with bumetanid effectively eliminated glycine-evoked a weak depolarization in rods, suggesting that NKCC1 maintains a high Cl(-) level in rods, which causes to depolarize in responding to glycine input.	Glycine	249-256	solute carrier family 12 member 2	Homo sapiens	161-166
18348205-7	2008	The results indicate that DRD3 is significantly associated with ND in EAs, and that rs6280, a functional polymorphism causing an amino acid change of serine to glycine (Ser9Gly) in the N-terminal extracellular domain of the D(3) receptor, likely is causative of the association between DRD3 and ND.	Glycine	160-167	dopamine receptor D3	Homo sapiens	26-30
18348205-7	2008	The results indicate that DRD3 is significantly associated with ND in EAs, and that rs6280, a functional polymorphism causing an amino acid change of serine to glycine (Ser9Gly) in the N-terminal extracellular domain of the D(3) receptor, likely is causative of the association between DRD3 and ND.	Glycine	160-167	dopamine receptor D3	Homo sapiens	286-290
18597079-3	2008	OBJECTIVE: We examined the involvement of the glycine coagonist site on the N-methyl-D: -aspartate receptor (NMDAR) glycine coagonist site in the modulation of negative and cognitive endophenotypes in mice.	Glycine	46-53	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	109-114
18597079-3	2008	OBJECTIVE: We examined the involvement of the glycine coagonist site on the N-methyl-D: -aspartate receptor (NMDAR) glycine coagonist site in the modulation of negative and cognitive endophenotypes in mice.	Glycine	116-123	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	76-107
18597079-3	2008	OBJECTIVE: We examined the involvement of the glycine coagonist site on the N-methyl-D: -aspartate receptor (NMDAR) glycine coagonist site in the modulation of negative and cognitive endophenotypes in mice.	Glycine	116-123	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	109-114
18597079-4	2008	MATERIALS AND METHODS: Behavioral phenotypes relevant to schizophrenia were assessed in Grin1(D481N) mice that have reduced NMDAR glycine affinity.	Glycine	130-137	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	88-93
18597079-4	2008	MATERIALS AND METHODS: Behavioral phenotypes relevant to schizophrenia were assessed in Grin1(D481N) mice that have reduced NMDAR glycine affinity.	Glycine	130-137	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	124-129
18597079-5	2008	RESULTS: Grin1(D481N) mutant mice showed abnormally persistent latent inhibition (LI) that was reversed by two agents that enhance NMDAR glycine site function, D: -serine (600 mg/kg) and ALX-5407 (1 mg/kg), and by the classical atypical antipsychotic clozapine (3 mg/kg).	Glycine	137-144	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	9-14
18597079-5	2008	RESULTS: Grin1(D481N) mutant mice showed abnormally persistent latent inhibition (LI) that was reversed by two agents that enhance NMDAR glycine site function, D: -serine (600 mg/kg) and ALX-5407 (1 mg/kg), and by the classical atypical antipsychotic clozapine (3 mg/kg).	Glycine	137-144	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	131-136
18597079-6	2008	Similarly, blockade of the NMDAR glycine site with the antagonist L-701,324 (5 mg/kg) induced persistent LI in C57BL6/J mice.	Glycine	33-40	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	27-32
18597079-11	2008	Antipsychotics that target the NMDAR glycine site may be beneficial in treating such psychiatric symptoms.	Glycine	37-44	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	31-36
18621125-4	2008	Transepithelial transport of the prototypic hPAT1 (SLC36A1) substrates l-proline and glycine were maximal after 21-28 days in culture.	Glycine	85-92	solute carrier family 36 member 1	Homo sapiens	44-49
18621125-4	2008	Transepithelial transport of the prototypic hPAT1 (SLC36A1) substrates l-proline and glycine were maximal after 21-28 days in culture.	Glycine	85-92	solute carrier family 36 member 1	Homo sapiens	51-58
18621125-5	2008	Based on proton-dependency and substrate kinetics the major apical uptake and transport of Gly and Pro in Caco-2 cell monolayers is hPAT1-mediated.	Glycine	91-94	solute carrier family 36 member 1	Homo sapiens	132-137
18566452-8	2008	Fluorescence polarization and surface plasmon resonance were used to determine that UBR1 binds, with a K(d) of approximately 1 microm, to either type-1 or type-2 destabilizing N-terminal residues of reporter peptides but does not bind to a stabilizing N-terminal residue such as Gly.	Glycine	279-282	E3 ubiquitin-protein ligase UBR1	Saccharomyces cerevisiae S288C	84-88
18533104-2	2008	In order to better understand the biological significance of this region on the structure, property and function of hGIF, we introduced a highly flexible residue, Gly, either in front of the (6)CPCP(9) motif (the IG6 mutant, TGCPCP) or in the middle of it (the IG8 mutant, TCPGCP) and investigated their structural and metal binding properties in detail.	Glycine	163-166	cobalamin binding intrinsic factor	Homo sapiens	116-120
18499677-4	2008	Computer-simulated modeling combined with site-directed mutagenesis of GPR92 indicated that Thr(97), Gly(98), Phe(101), and Arg(267) of GPR92 are responsible for the interaction of GPR92 with FPP and NAG.	Glycine	101-104	lysophosphatidic acid receptor 5	Homo sapiens	71-76
18499677-4	2008	Computer-simulated modeling combined with site-directed mutagenesis of GPR92 indicated that Thr(97), Gly(98), Phe(101), and Arg(267) of GPR92 are responsible for the interaction of GPR92 with FPP and NAG.	Glycine	101-104	lysophosphatidic acid receptor 5	Homo sapiens	136-141
18499677-4	2008	Computer-simulated modeling combined with site-directed mutagenesis of GPR92 indicated that Thr(97), Gly(98), Phe(101), and Arg(267) of GPR92 are responsible for the interaction of GPR92 with FPP and NAG.	Glycine	101-104	lysophosphatidic acid receptor 5	Homo sapiens	136-141
20641316-15	2004	The peptide contains the tripeptide motif Pro-Leu-Gly for MMP7 recognition, and the cleavage site is located between the Gly and Leu residues.	Glycine	50-53	matrix metallopeptidase 7	Homo sapiens	58-62
18507461-2	2008	These linker units are formed by attaching glycine to one carboxyl group of cis-1,2-cyclohexanedicarboxylic acid (CHDA).	Glycine	43-50	suppressor of cytokine signaling 1	Homo sapiens	76-81
18320559-8	2008	CONCLUSIONS: Gly/gly DRD-3 genotype predicted statistically and clinically significantly better acute positive symptom reduction compared with other ser-9-gly genotypes in patients treated with olanzapine.	Glycine	17-20	dopamine receptor D3	Homo sapiens	21-26
18364727-1	2008	Osteopontin (OPN), a large secreted glycoprotein with an arginine, glycine, aspartate (RGD) motif, can bind and signal through cellular integrin receptors.	Glycine	67-74	secreted phosphoprotein 1	Homo sapiens	0-11
18364727-1	2008	Osteopontin (OPN), a large secreted glycoprotein with an arginine, glycine, aspartate (RGD) motif, can bind and signal through cellular integrin receptors.	Glycine	67-74	secreted phosphoprotein 1	Homo sapiens	13-16
18331477-10	2008	Our results demonstrate that chronic saturating level of glycine induces significant changes in NMDAR localization and kinetic.	Glycine	57-64	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	96-101
18243325-2	2008	The fourth transmembrane domain (TM4) housing the disease-causing mutations both in Nramp1 and Nramp2 at the conserved two adjacent glycine residues, was implicated to serve an important biological function.	Glycine	132-139	tropomyosin 4	Rattus norvegicus	33-36
18403029-1	2008	Gephyrin is a multifunctional protein responsible for molybdenum cofactor synthesis and the clustering of glycine and GABA(A) receptors at inhibitory synapses.	Glycine	106-113	gephyrin	Homo sapiens	0-8
20832426-5	2010	In the present study this technology was applied to the glycine transporter type-1 (GlyT1) protein which is responsible for the uptake of synaptic glycine in the forebrain and has been implicated as a therapeutic target for the treatment of schizophrenia.	Glycine	56-63	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	84-89
20686071-5	2010	We have studied the signaling events induced in human umbilical venous endothelial cells (HUVECs) by aortic microfibrils as well as recombinant fibrillin-1 Arg-Gly-Asp (RGD)-containing fragments PF9 and PF14.	Glycine	160-163	fibrillin 1	Homo sapiens	144-155
20679339-2	2010	Matrix metalloproteinases (MMPs) cleave collagen after the Gly residue of the triplet sequence Gly~[Ile/Leu]-[Ala/Leu] at a single, unique, position along the peptide chain.	Glycine	59-62	matrix metallopeptidase 1	Homo sapiens	27-31
20679339-2	2010	Matrix metalloproteinases (MMPs) cleave collagen after the Gly residue of the triplet sequence Gly~[Ile/Leu]-[Ala/Leu] at a single, unique, position along the peptide chain.	Glycine	95-98	matrix metallopeptidase 1	Homo sapiens	27-31
20800579-0	2010	The role of the glycine triad in human glutathione synthetase.	Glycine	16-23	glutathione synthetase	Homo sapiens	39-61
20800579-1	2010	Experimental kinetics and computational modeling of human glutathione synthetase (hGS) support the significant role of the G-loop glycine triad (G369, G370, G371) for activity of this ATP-grasp enzyme.	Glycine	130-137	glutathione synthetase	Homo sapiens	58-80
20860669-10	2010	CONCLUSIONS AND IMPLICATIONS: Our results suggest that NAGly enhanced inhibitory glycinergic synaptic transmission within the superficial dorsal horn by blocking glycine uptake via GLYT2.	Glycine	81-88	solute carrier family 6 member 5	Rattus norvegicus	181-186
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	71-74	solute carrier family 36 member 1	Homo sapiens	43-50
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	71-74	solute carrier family 36 member 1	Homo sapiens	52-57
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	43-50
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	52-57
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	43-50
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	52-57
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	43-50
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	52-57
20880398-0	2010	The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.	Glycine	75-78	solute carrier family 36 member 1	Homo sapiens	43-50
20634289-7	2010	Mutation at putative myristoylation residue glycine 2 altered plasma membrane localization of BON1 and rendered BON1 inactive.	Glycine	44-51	Calcium-dependent phospholipid-binding Copine family protein	Arabidopsis thaliana	94-98
20634289-7	2010	Mutation at putative myristoylation residue glycine 2 altered plasma membrane localization of BON1 and rendered BON1 inactive.	Glycine	44-51	Calcium-dependent phospholipid-binding Copine family protein	Arabidopsis thaliana	112-116
20728429-4	2010	Size exclusion chromatography indicated that the isolated core fragment retains the ability to self-associate while circular dichroism analysis confirmed that the Purbeta core domain is stably folded in the absence of glycine-rich N- and C-terminal sequences.	Glycine	218-225	purine rich element binding protein B	Homo sapiens	163-170
20530479-7	2010	We also report that the ubiquitin ligase Nedd4-2 interacts with Na(v)1.6 via a Pro-Ser-Tyr(1945) motif in the C terminus of the channel and reduces Na(v)1.6 current density, and we show that this regulation requires both the Pro-Gly-Ser-Pro motif in L1 and the Pro-Ser-Tyr motif in the C terminus.	Glycine	229-232	neural precursor cell expressed, developmentally down-regulated gene 4-like	Mus musculus	41-48
20548263-3	2010	We have asked whether a hybrid molecule in which a soluble fusion protein containing CD200, CD200Fc, was linked to TGF-beta through a glycine linker (Gly6) functions as a superior immunosuppressant molecule when compared with CD200Fc or TGF-beta alone, or in combination.	Glycine	134-141	CD200 antigen	Mus musculus	85-90
20498232-9	2010	Interestingly, GlyT1, the glial glycine transporter, regulates the strength of tonic glycinergic inhibition of these glycine-dominant neurons.	Glycine	32-39	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	15-20
20468048-2	2010	In newborn mice, GlyT1 is crucial for efficient termination of glycine-mediated inhibitory neurotransmission.	Glycine	63-70	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	17-22
20468048-8	2010	Thus, glial GlyT1 is critical for the regulation of glycine levels at inhibitory synapses only during early postnatal life.	Glycine	52-59	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	12-17
20375021-0	2010	Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism.	Glycine	91-98	aminomethyltransferase	Homo sapiens	21-43
20375021-1	2010	Aminomethyltransferase, a component of the glycine cleavage system termed T-protein, reversibly catalyzes the degradation of the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein, resulting in the production of ammonia, 5,10-methylenetetrahydrofolate, and dihydrolipoate-bearing H-protein in the presence of tetrahydrofolate.	Glycine	43-50	aminomethyltransferase	Homo sapiens	0-22
20375021-1	2010	Aminomethyltransferase, a component of the glycine cleavage system termed T-protein, reversibly catalyzes the degradation of the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein, resulting in the production of ammonia, 5,10-methylenetetrahydrofolate, and dihydrolipoate-bearing H-protein in the presence of tetrahydrofolate.	Glycine	151-158	aminomethyltransferase	Homo sapiens	0-22
20138995-2	2010	Unexpectedly, the well known GABA(B) receptor antagonist CGP35348 and, in part, the compound CGP52432, are now found to inhibit on their own the K(+)-evoked exocytosis of glycine when added at low micromolar concentrations to superfused mouse glycinergic nerve endings prelabelled with [(3)H]glycine through GLYT2 transporters.	Glycine	171-178	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	308-313
20405902-10	2010	It is shown that such calculations can generate improved estimates (i.e., approximately 2%) of the experimental frequencies for glycine and glycine.H(2)O, provided that the potential energy surfaces are modeled with high-level ab initio approaches (MP2/aug-cc-pVDZ).	Glycine	128-135	tryptase pseudogene 1	Homo sapiens	249-252
20405902-10	2010	It is shown that such calculations can generate improved estimates (i.e., approximately 2%) of the experimental frequencies for glycine and glycine.H(2)O, provided that the potential energy surfaces are modeled with high-level ab initio approaches (MP2/aug-cc-pVDZ).	Glycine	140-147	tryptase pseudogene 1	Homo sapiens	249-252
20356736-2	2010	SAR studies indicate that different substituents on the aryloxazole/thiazole moieties as well as the choice of carbamate substituent on the glycine moiety can significantly modulate the selectivity of PPARalpha versus PPARgamma.	Glycine	140-147	peroxisome proliferator activated receptor alpha	Homo sapiens	201-210
20097255-4	2010	While glutamate activates triheteromeric NMDARs composed of NR1/NR2/NR3A subunits, glycine is sufficient to activate diheteromeric NR1/NR3A-containing receptors.	Glycine	83-90	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	135-139
20375004-2	2010	We report that stiff skin syndrome (SSS), an autosomal dominant congenital form of scleroderma, is caused by mutations in the sole Arg-Gly-Asp sequence-encoding domain of fibrillin-1 that mediates integrin binding.	Glycine	135-138	fibrillin 1	Homo sapiens	171-182
20231318-5	2010	Second, mutation of a conserved glycine, Gly100 in the TEN (telomerase essential N-terminal) domain of TERT, abolished the enhancement of telomerase processivity by POT1-TPP1, in contrast to other single amino acid mutations.	Glycine	32-39	telomerase reverse transcriptase	Homo sapiens	103-107
20231318-5	2010	Second, mutation of a conserved glycine, Gly100 in the TEN (telomerase essential N-terminal) domain of TERT, abolished the enhancement of telomerase processivity by POT1-TPP1, in contrast to other single amino acid mutations.	Glycine	32-39	protection of telomeres 1	Homo sapiens	165-169
19468822-2	2010	In plants, some amino acids work as buffers: during photorespiration, ammonium derived from the conversion of glycine to serine is promptly reassimilated into glutamate by the glutamine synthetase (GS-2)/ferredoxin-dependent glutamate synthase (Fd-GOGAT) cycle.	Glycine	110-117	hypothetical protein	Arabidopsis thaliana	176-196
20044973-10	2010	We speculate that the structural and functional changes related to the glycine to serine amino acid substitution in the S5 segment may also influence the activity of the whole KvLQT1 channel.	Glycine	71-78	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	176-182
18307268-5	2008	Genetic testing revealed a heterozygous G to C mutation at the first base of codon 389 of the MAPT gene, changing glycine to arginine (G389R), in the patient and his unaffected elderly father.	Glycine	114-121	microtubule associated protein tau	Homo sapiens	94-98
18256394-2	2008	The genetic basis of most cases of this syndrome is a change from glycine GGC to glycine GGT in codon 608 of the lamin A (LMNA) gene, which activates a cryptic splice donor site to produce abnormal lamin A; this disrupts the nuclear membrane and alters transcription.	Glycine	66-73	lamin A/C	Homo sapiens	113-120
28057537-3	2017	Na+-K+-2Cl- co-transporter 1 (NKCC1) and K+-Cl- co-transporter 2 (KCC2) generally dictate the tone of GABA/glycine inhibition by regulating intracellular chloride concentrations.	Glycine	107-114	solute carrier family 12 member 2	Homo sapiens	30-35
19695284-2	2010	The NMDAR contains a D-serine/glycine site on the NR1 subunit that may be a promising therapeutic target for psychiatric illness.	Glycine	30-37	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	4-9
19695284-2	2010	The NMDAR contains a D-serine/glycine site on the NR1 subunit that may be a promising therapeutic target for psychiatric illness.	Glycine	30-37	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	50-53
28137860-3	2017	Glycine amidinotransferase (GATM) catalyzes the rate-limiting step of creatine biosynthesis: the transfer of an amidino group from arginine to glycine to form ornithine and guanidinoacetate.	Glycine	143-150	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	Mus musculus	28-32
19695284-3	2010	This review outlines the complex regulation of endogenous NMDAR D-serine/glycine site agonists and explores their contribution to schizophrenia pathogenesis and their potential clinical utility.	Glycine	73-80	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	58-63
19695284-4	2010	Genetic studies have associated genes influencing NMDAR D-serine/glycine site activation with an increased susceptibility to schizophrenia.	Glycine	65-72	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	50-55
19695284-6	2010	Genetically modified mice with aberrant NMDAR D-serine/glycine site function model certain features of the negative and cognitive symptoms of schizophrenia, and similar behavioral abnormalities have been observed in other candidate genes models.	Glycine	55-62	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	40-45
19695284-7	2010	Compounds that directly activate the NMDAR D-serine/glycine site or inhibit glycine transport have demonstrated beneficial effects in preclinical models and clinical trials.	Glycine	52-59	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	37-42
18256394-2	2008	The genetic basis of most cases of this syndrome is a change from glycine GGC to glycine GGT in codon 608 of the lamin A (LMNA) gene, which activates a cryptic splice donor site to produce abnormal lamin A; this disrupts the nuclear membrane and alters transcription.	Glycine	66-73	lamin A/C	Homo sapiens	122-126
18256394-2	2008	The genetic basis of most cases of this syndrome is a change from glycine GGC to glycine GGT in codon 608 of the lamin A (LMNA) gene, which activates a cryptic splice donor site to produce abnormal lamin A; this disrupts the nuclear membrane and alters transcription.	Glycine	66-73	lamin A/C	Homo sapiens	198-205
18256394-2	2008	The genetic basis of most cases of this syndrome is a change from glycine GGC to glycine GGT in codon 608 of the lamin A (LMNA) gene, which activates a cryptic splice donor site to produce abnormal lamin A; this disrupts the nuclear membrane and alters transcription.	Glycine	81-88	lamin A/C	Homo sapiens	113-120
18256394-2	2008	The genetic basis of most cases of this syndrome is a change from glycine GGC to glycine GGT in codon 608 of the lamin A (LMNA) gene, which activates a cryptic splice donor site to produce abnormal lamin A; this disrupts the nuclear membrane and alters transcription.	Glycine	81-88	lamin A/C	Homo sapiens	122-126
18256394-2	2008	The genetic basis of most cases of this syndrome is a change from glycine GGC to glycine GGT in codon 608 of the lamin A (LMNA) gene, which activates a cryptic splice donor site to produce abnormal lamin A; this disrupts the nuclear membrane and alters transcription.	Glycine	81-88	lamin A/C	Homo sapiens	198-205
17657484-4	2008	We investigated the role of these two positions in heteromeric Kir4.1/Kir5.1 channels, which are unique amongst Kir channels in that both subunits lack a conserved glycine at the upper hinge position.	Glycine	164-171	potassium inwardly rectifying channel subfamily J member 10	Homo sapiens	63-69
20133649-0	2010	Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I.	Glycine	25-32	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	48-83
27419919-6	2017	Furthermore, we utilized a patch-clamp biosensor method to confirm the glycine release from astrocytes by using GlyRalpha1 and Glybeta-expressing HEK293T cells, and detected significant glycine-evoked current upon DA stimulation.	Glycine	71-78	glycine receptor alpha 1	Homo sapiens	112-122
19889552-3	2010	An atypical JAK3-SCID case carrying a single glutamate to glycine substitution mutation (E481G) in the JH3 domain of one JAK3 allele, and a deletion mutation (del482-596) in the JH3 and JH2 domains of the other allele was reported previously.	Glycine	58-65	Janus kinase 3	Homo sapiens	12-16
18245597-2	2008	The disorder is caused by a recurrent missense mutation in the glycine-serine activation domain of activin A receptor type I, a bone morphogenetic protein (BMP) type-I receptor, in all classically affected individuals.	Glycine	63-70	bone morphogenetic protein 1	Homo sapiens	128-154
18245597-2	2008	The disorder is caused by a recurrent missense mutation in the glycine-serine activation domain of activin A receptor type I, a bone morphogenetic protein (BMP) type-I receptor, in all classically affected individuals.	Glycine	63-70	bone morphogenetic protein 1	Homo sapiens	156-159
27836671-5	2017	The cardioprotective effect of glycine disappeared when endogenous glycine receptor alpha2 was knocked down by mRNA interference in rats.	Glycine	31-38	glycine receptor, alpha 2	Rattus norvegicus	67-90
29465378-6	2017	Amino acid analysis of HAPA-elastin showed a high content (81.5%) of hydrophobic amino acids such as Gly, Ala, Val, and Pro.	Glycine	101-104	LOC100620140	Sus scrofa	28-35
18162597-3	2008	Previous studies of Arabidopsis thaliana root cells showed that the amino acids alanine (Ala), asparagine (Asn), cysteine (Cys), Glu, glycine (Gly), and serine trigger transient Ca(2+) influx and membrane depolarization by a mechanism that depends on the GLR3.3 gene.	Glycine	134-141	glutamate receptor 3.3	Arabidopsis thaliana	255-261
20206586-0	2010	Abnormally low HbA1c secondary to hemoglobin J-Baltimore [beta 16(A13) Gly--&gt;Asp].	Glycine	71-74	immunoglobulin kappa variable 2D-18 (pseudogene)	Homo sapiens	66-69
20166936-6	2010	In COL4A1 stroke syndrome most mutations are missense mutations involving a glycine residue, including G562E, G749S, G805R, G1130D, G1236R, G1423R, G720D, G1580R, and G755R.	Glycine	76-83	collagen type IV alpha 1 chain	Homo sapiens	3-9
32714574-3	2017	The phenotype of a glycinergic neuron is determined by the expression of at least two proteins: GlyT2, a plasma membrane transporter of glycine, and VIAAT, a vesicular transporter shared by glycine and GABA.	Glycine	19-26	solute carrier family 32 member 1	Homo sapiens	149-154
27753536-2	2016	Ectopic expression of PCNA fused with ubiquitin (Ub) lacking the 2 C-terminal Gly residues resembles PCNA monoubiquitination-mediated TLS.	Glycine	78-81	proliferating cell nuclear antigen	Homo sapiens	22-26
19802897-0	2010	Missense mutations of conserved glycine residues in fibrillin-1 highlight a potential subtype of cb-EGF-like domains.	Glycine	32-39	fibrillin 1	Homo sapiens	52-63
19802897-2	2010	These variants, predicted to result in Glycine substitutions are located at the third position of a 4 amino acids loop-region of calcium-binding Epidermal Growth Factor-like (cb-EGF) fibrillin-1 domains 5, 9, 24, 25 and 32.	Glycine	39-46	fibrillin 1	Homo sapiens	183-194
19802897-4	2010	Extending these analyses to all Glycine residue at position 3 of this 4 residues loop in fibrillin-1 cb-EGF with the UMD predictor tool and alignment of 2038 available related sequences strongly support a steric strain that only allows Glycine or even Alanine residues for domain structure maintenance and for the fibrillin functions.	Glycine	32-39	fibrillin 1	Homo sapiens	89-100
19877718-8	2009	Since the central Gly in the neuromodulin sequence is conserved in half of all known IQ domains, these results suggest that the presence or absence of this residue defines two major functional classes.	Glycine	18-21	growth associated protein 43	Homo sapiens	29-41
26619992-5	2008	In this paper HSMD is developed further as applied to the flexible 7-residue surface loop, 304-310 (Gly-His-Gly-Ala-Gly-Gly-Ser) of the enzyme porcine pancreatic alpha-amylase.	Glycine	100-103	amylase alpha 2A	Homo sapiens	151-175
26619992-5	2008	In this paper HSMD is developed further as applied to the flexible 7-residue surface loop, 304-310 (Gly-His-Gly-Ala-Gly-Gly-Ser) of the enzyme porcine pancreatic alpha-amylase.	Glycine	108-111	amylase alpha 2A	Homo sapiens	151-175
26619992-5	2008	In this paper HSMD is developed further as applied to the flexible 7-residue surface loop, 304-310 (Gly-His-Gly-Ala-Gly-Gly-Ser) of the enzyme porcine pancreatic alpha-amylase.	Glycine	108-111	amylase alpha 2A	Homo sapiens	151-175
26619992-5	2008	In this paper HSMD is developed further as applied to the flexible 7-residue surface loop, 304-310 (Gly-His-Gly-Ala-Gly-Gly-Ser) of the enzyme porcine pancreatic alpha-amylase.	Glycine	108-111	amylase alpha 2A	Homo sapiens	151-175
27933794-0	2016	Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.	Glycine	43-50	histone deacetylase 8	Homo sapiens	99-120
17597258-1	2008	It is widely accepted that glycine transporters of the GLYT1 type are situated on astrocytes whereas GLYT2 are present on glycinergic neuronal terminals where they mediate glycine uptake.	Glycine	27-34	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	55-60
19843525-1	2009	The vesicular inhibitory amino acid transporter (VIAAT) is a synaptic vesicle protein responsible for the vesicular storage of gamma-aminobutyrate (GABA) and glycine which plays an essential role in GABAergic and glycinergic neurotransmission.	Glycine	158-165	solute carrier family 32 member 1	Homo sapiens	49-54
19843525-7	2009	Essentially the same results were obtained with glycine, another substrate of VIAAT.	Glycine	48-55	solute carrier family 32 member 1	Homo sapiens	78-83
19843525-8	2009	These results demonstrated that VIAAT is a vesicular Cl(-) transporter that co-transports Cl(-) with GABA or glycine in a Deltapsi dependent manner.	Glycine	109-116	solute carrier family 32 member 1	Homo sapiens	32-37
18004849-1	2007	A recently developed extended Lagrangian model employing localized basis functions and nonperiodic boundary conditions (GLOB/ADMP) was applied to the radicals issuing from the homolytic breaking of the C(alpha)-H(alpha) bond of glycine in aqueous solution at different pH values.	Glycine	228-235	serine palmitoyltransferase small subunit B	Homo sapiens	125-129
27933794-5	2016	To probe the catalytic importance of the glycine-rich loop in HDAC8, we rigidified this loop by preparing the G302A, G303A, G304A, and G305A mutants and measured their steady state kinetics and determined their X-ray crystal structures.	Glycine	41-48	histone deacetylase 8	Homo sapiens	62-67
27798331-0	2016	Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts.	Glycine	0-7	protein tyrosine kinase 2 beta	Homo sapiens	49-65
27798331-4	2016	OBJECTIVE: This study was conducted with a mouse myoblast cell line, C2C12, to test the hypothesis that glycine activates protein kinase B/mammalian target of rapamycin (Akt/mTOR), as well as inhibits 5"-adenosine monophosphate-activated protein kinase (AMPK) and the expression of genes for proteolysis.	Glycine	104-111	protein tyrosine kinase 2 beta	Homo sapiens	122-138
17997397-8	2007	Using size exclusion chromatography we found that just as for NR1, a large fraction of NR3A exists as monomers and dimers, suggesting that these two glycine binding subunits behave similarly with regard to receptor assembly and trafficking.	Glycine	149-156	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	87-91
20092573-1	2009	We examined the role of GlyT1, the high-affinity glycine transporter, in the mouse retina with an emphasis on the role of glycine as a coagonist of N-methyl-D-aspartic acid (NMDA) receptors.	Glycine	49-56	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	24-29
27548707-3	2016	Here, we show that chromatin deformation as well as force-induced transcription of a green fluorescent protein (GFP)-tagged bacterial-chromosome dihydrofolate reductase (DHFR) transgene can be visualized in a living cell by using three-dimensional magnetic twisting cytometry to apply local stresses on the cell surface via an Arg-Gly-Asp-coated magnetic bead.	Glycine	331-334	dihydrofolate reductase	Homo sapiens	145-168
20092573-3	2009	Capillary electrophoresis was used to separate and quantitatively measure glycine release from isolated retina preparations; pharmacologically blocking GlyT1 with N-[3-([1,1-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine in the WT retina generated a significantly larger accumulation of glycine into the bathing environment when compared with the GlyT1(-/+) retinas.	Glycine	227-234	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	152-157
20093739-1	2009	In a previous paper, we pointed out that the capability to synthesize glycine from serine is constrained by the stoichiometry of the glycine hydroxymethyltransferase reaction, which limits the amount of glycine produced to be no more than equimolar with the amount of C 1 units produced.	Glycine	70-77	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	268-271
20093739-1	2009	In a previous paper, we pointed out that the capability to synthesize glycine from serine is constrained by the stoichiometry of the glycine hydroxymethyltransferase reaction, which limits the amount of glycine produced to be no more than equimolar with the amount of C 1 units produced.	Glycine	133-140	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	268-271
17962466-10	2007	Unexpectedly, K18 bearing phakosin HIM resulted in normal IF assembly, despite the presence of an otherwise disease-causing R-C substitution, and two helix-disrupting glycines.	Glycine	167-175	keratin 18	Homo sapiens	14-17
17962467-0	2007	Mapping of glutathione and its precursor amino acids reveals a role for GLYT2 in glycine uptake in the lens core.	Glycine	81-88	solute carrier family 6 member 5	Rattus norvegicus	72-77
27548707-3	2016	Here, we show that chromatin deformation as well as force-induced transcription of a green fluorescent protein (GFP)-tagged bacterial-chromosome dihydrofolate reductase (DHFR) transgene can be visualized in a living cell by using three-dimensional magnetic twisting cytometry to apply local stresses on the cell surface via an Arg-Gly-Asp-coated magnetic bead.	Glycine	331-334	dihydrofolate reductase	Homo sapiens	170-174
19715676-0	2009	Role of P2 glycine in determining the specificity of antithrombin reaction with coagulation proteases.	Glycine	11-18	serpin family C member 1	Homo sapiens	53-65
27659109-8	2016	The LTP impairment could be rescued by administering the NMDAR co-agonist, glycine.	Glycine	75-82	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	57-62
17907847-2	2007	The glycine transporter (GlyT1) regulates levels of the neurotransmitter glycine, a coagonist of the N-methyl-D-aspartate receptor (NMDAR), and as such may represent a novel site for developing cognition-enhancing drugs.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	25-30
17907847-2	2007	The glycine transporter (GlyT1) regulates levels of the neurotransmitter glycine, a coagonist of the N-methyl-D-aspartate receptor (NMDAR), and as such may represent a novel site for developing cognition-enhancing drugs.	Glycine	4-11	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	101-130
27683223-4	2016	We also show that Chtop interacts with exon 2 of Chtop mRNA via its arginine-glycine-rich (RG) domain, and with intron 2 via its N-terminal (N1) domain; both are required for retention of intron 2.	Glycine	77-84	chromatin target of PRMT1	Homo sapiens	18-23
17907847-2	2007	The glycine transporter (GlyT1) regulates levels of the neurotransmitter glycine, a coagonist of the N-methyl-D-aspartate receptor (NMDAR), and as such may represent a novel site for developing cognition-enhancing drugs.	Glycine	4-11	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	132-137
17907847-6	2007	The longer-lasting habituation displayed by the GlyT1 mice is consistent with a role for glycine/NMDAR-dependent synaptic plasticity in supporting a nonassociative, short-term memory trace of a recently experienced stimulus.	Glycine	89-96	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	48-53
19758826-4	2009	We propose that this newly discovered unstable M-hemoglobin (M-Hb) variant, named Hb Dothan [GGT/GAG-->GAG//Gly/Glu-->Glu], is caused by a shift in the amino acid sequence and altered packing of the B and E helices during beta globin synthesis, and also changes the orientation of the critical proximal and distal histidine in the F and E helices respectively.	Glycine	108-111	hemoglobin subunit beta	Homo sapiens	222-233
19905915-8	2009	We found a significant association between favorable therapeutic response to inhaled beta(2)-adrenergic agonists in asthmatic children and the Arg/Arg phenotype at position 16 of the beta(2)AR [OR = 1.77; 95% CI (1.01; 3.1); p = 0.029], compared with the Arg/Gly or Gly/Gly phenotypes.	Glycine	259-262	adenosine A2a receptor	Homo sapiens	183-192
19905915-8	2009	We found a significant association between favorable therapeutic response to inhaled beta(2)-adrenergic agonists in asthmatic children and the Arg/Arg phenotype at position 16 of the beta(2)AR [OR = 1.77; 95% CI (1.01; 3.1); p = 0.029], compared with the Arg/Gly or Gly/Gly phenotypes.	Glycine	266-269	adenosine A2a receptor	Homo sapiens	183-192
19905915-8	2009	We found a significant association between favorable therapeutic response to inhaled beta(2)-adrenergic agonists in asthmatic children and the Arg/Arg phenotype at position 16 of the beta(2)AR [OR = 1.77; 95% CI (1.01; 3.1); p = 0.029], compared with the Arg/Gly or Gly/Gly phenotypes.	Glycine	266-269	adenosine A2a receptor	Homo sapiens	183-192
27683223-4	2016	We also show that Chtop interacts with exon 2 of Chtop mRNA via its arginine-glycine-rich (RG) domain, and with intron 2 via its N-terminal (N1) domain; both are required for retention of intron 2.	Glycine	77-84	chromatin target of PRMT1	Homo sapiens	49-54
17892480-1	2007	Type 2 glycine transporter (GlyT2) mediates intracellular glycine transport and is expressed selectively in glycinergic neurons.	Glycine	7-14	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	28-33
27718463-5	2016	One newly designed and easily synthesized phosphorylated BChE nonapeptide with one Gly-to-Ala mutation was successfully reported to serve as internal standard instead of traditional isotopically labeled BChE nonapeptide.	Glycine	83-86	butyrylcholinesterase	Homo sapiens	57-61
19767735-5	2009	Both a genomic pmt4 deletion and the insertion of a stretch of glycines in Wsc1 result in substantial alterations in protein spring properties, supporting the important role of glycosylation at the extracellular serine/threonine-rich region.	Glycine	63-71	Slg1p	Saccharomyces cerevisiae S288C	75-79
27665180-0	2016	Design and synthesis of novel HDAC8 inhibitory 2,5-disubstituted-1,3,4-oxadiazoles containing glycine and alanine hybrids with anti cancer activity.	Glycine	94-101	histone deacetylase 8	Homo sapiens	30-35
19710017-5	2009	Crystal structures and biochemical analyses show that human glycyl-tRNA synthetase (GlyRS) produces Ap4A by direct condensation of two ATPs, independent of glycine concentration.	Glycine	156-163	glycyl-tRNA synthetase 1	Homo sapiens	60-82
19710017-5	2009	Crystal structures and biochemical analyses show that human glycyl-tRNA synthetase (GlyRS) produces Ap4A by direct condensation of two ATPs, independent of glycine concentration.	Glycine	156-163	glycyl-tRNA synthetase 1	Homo sapiens	84-89
17171344-5	2007	Screening for SCN5A and HERG candidate genes identified a heterozygous missense mutation 1810G--&gt;A in exon 7 of HERG that leads to the substitution of the amino acid glycine by serine (G604S); this mutation was located in the S5/pore region of the HERG protein and was associated with a malignant phenotype.	Glycine	169-176	sodium voltage-gated channel alpha subunit 5	Homo sapiens	14-19
17171344-5	2007	Screening for SCN5A and HERG candidate genes identified a heterozygous missense mutation 1810G--&gt;A in exon 7 of HERG that leads to the substitution of the amino acid glycine by serine (G604S); this mutation was located in the S5/pore region of the HERG protein and was associated with a malignant phenotype.	Glycine	169-176	potassium voltage-gated channel subfamily H member 2	Homo sapiens	24-28
17171344-5	2007	Screening for SCN5A and HERG candidate genes identified a heterozygous missense mutation 1810G--&gt;A in exon 7 of HERG that leads to the substitution of the amino acid glycine by serine (G604S); this mutation was located in the S5/pore region of the HERG protein and was associated with a malignant phenotype.	Glycine	169-176	potassium voltage-gated channel subfamily H member 2	Homo sapiens	115-119
17171344-5	2007	Screening for SCN5A and HERG candidate genes identified a heterozygous missense mutation 1810G--&gt;A in exon 7 of HERG that leads to the substitution of the amino acid glycine by serine (G604S); this mutation was located in the S5/pore region of the HERG protein and was associated with a malignant phenotype.	Glycine	169-176	potassium voltage-gated channel subfamily H member 2	Homo sapiens	115-119
17502428-7	2007	The NMDA receptor glycine site agonist, d-serine, partially activated NR1/NR3A/NR3B receptors, whereas the antagonist, 5,7-dichloro-kynurenic acid, inhibited receptor currents.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	74-78
19213874-5	2009	The results demonstrate that insulin-induced hypercontractility after 8 days of tissue culture was fully prevented by combined treatment of BTSM-strips with the laminin competing peptides Tyr-Ile-Gly-Ser-Arg (YIGSR) and Arg-Gly-Asp-Ser (RGDS).	Glycine	196-199	insulin	Bos taurus	29-36
19213874-5	2009	The results demonstrate that insulin-induced hypercontractility after 8 days of tissue culture was fully prevented by combined treatment of BTSM-strips with the laminin competing peptides Tyr-Ile-Gly-Ser-Arg (YIGSR) and Arg-Gly-Asp-Ser (RGDS).	Glycine	224-227	insulin	Bos taurus	29-36
27665180-10	2016	Novel 1,3,4-oxadizole substituted with glycine/alanine showed HDAC8 inhibition.	Glycine	39-46	histone deacetylase 8	Homo sapiens	62-67
27654951-6	2016	A MS-based interactome study revealed that the glycine substitutions facilitate binding of B/NS1 to heat shock protein 90-beta (HSP90beta).	Glycine	47-54	heat shock protein 90 alpha family class B member 1	Homo sapiens	128-137
19601712-1	2009	Thioredoxin-1 (TRX) is a small (14 kDa) multifunctional protein with the redox-active site Cys-Gly-Pro-Cys.	Glycine	95-98	thioredoxin	Homo sapiens	0-13
19601712-1	2009	Thioredoxin-1 (TRX) is a small (14 kDa) multifunctional protein with the redox-active site Cys-Gly-Pro-Cys.	Glycine	95-98	thioredoxin	Homo sapiens	15-18
25721693-9	2016	GLY reduced the levels of proteins, including nuclear NF-kappaB (p65 and p50), p-IKK (ser176), p-IkappaB, p-AKT, p-ERK, and nuclear Egr-1 in a time and dose-dependent manner.	Glycine	0-3	eukaryotic translation initiation factor 2 alpha kinase 3	Homo sapiens	113-118
17473056-7	2007	The key feature seems to be an arginine residue uniquely present at the 514-equivalent position in hERG2, where the other two isoforms possess a glycine.	Glycine	145-152	potassium voltage-gated channel subfamily H member 6	Homo sapiens	99-104
25721693-9	2016	GLY reduced the levels of proteins, including nuclear NF-kappaB (p65 and p50), p-IKK (ser176), p-IkappaB, p-AKT, p-ERK, and nuclear Egr-1 in a time and dose-dependent manner.	Glycine	0-3	early growth response 1	Homo sapiens	132-137
26399641-2	2016	In a recent transgenic mouse model of spinocerebellar ataxia 14, the ser361-to-gly (S361G) mutation of the protein kinase C gamma (PKCgamma) gene was expressed in Purkinje cells.	Glycine	79-82	protein kinase C, gamma	Mus musculus	107-129
17698249-4	2007	The conformation of [Nle(15)] gastrin-17 consisted of two short helices between Leu(5)-Glu(9) and Ala(11)-Trp(14), with the one helix terminating in a type I beta-turn spanning Gly(13)-Asp(16).	Glycine	177-180	gastrin	Homo sapiens	30-37
19676133-5	2009	Among these genes, a nonsynonymous single-nucleotide polymorphism which generates the variation of Gly-137 and Asp-137 in the MMP-7 gene was found to be strongly associated with the development of liver cirrhosis.	Glycine	99-102	matrix metallopeptidase 7	Homo sapiens	126-131
19757839-2	2009	The substitution of the His(4)-Pro(5) dipeptide sequence by the constrained Trp analogue Aia-Gly, in combination with beta(2)hVal substitution at the N-terminus, provided a new stable analogue H-(R)-beta(2)hVal-Tyr-Ile-Aia-Gly-Phe-OH (AL-40) that is a potent ligand for the Ang IV receptor IRAP and selective versus AP-N and the AT1 receptor.	Glycine	93-96	interleukin 1 receptor antagonist	Homo sapiens	290-294
19452450-8	2009	Gly alone also significantly increased gene transactivation by the introduction of runt-related transcription factor-2 (Runx2) in COS7 cells transfected with NR1 and NR3A subunits, while D-Ser significantly prevented the increase by Gly without affecting the promoter activity of Runx2.	Glycine	233-236	runt related transcription factor 2	Mus musculus	120-125
26399641-2	2016	In a recent transgenic mouse model of spinocerebellar ataxia 14, the ser361-to-gly (S361G) mutation of the protein kinase C gamma (PKCgamma) gene was expressed in Purkinje cells.	Glycine	79-82	protein kinase C, gamma	Mus musculus	131-139
19564338-7	2009	Mass spectrometric analysis revealed that ADAM10, but not ADAM9, cleaved PrP between Gly(228) and Arg(229), three residues away from the site of glycosylphosphatidylinositol anchor attachment.	Glycine	85-88	a disintegrin and metallopeptidase domain 10	Mus musculus	42-48
27606944-6	2016	Because glycolic acid and glycine are dominant products from a Strecker synthesis starting from formaldehyde and HCN, this study sheds light on potential pathways to prebiotic formation of oligopeptides via oligoesters.	Glycine	26-33	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	113-116
19596793-3	2009	CDSN displays adhesive properties, mostly attributable to its N-terminal glycine-rich domain, and is sequentially proteolyzed as corneocytes migrate towards the skin surface.	Glycine	73-80	corneodesmosin	Mus musculus	0-4
17581952-13	2007	These results suggest that glycine 116 is required for C-terminal processing of GABARAP and that processing is essential for the localization of GABARAP and its functions as a trafficking protein.	Glycine	27-34	GABA type A receptor-associated protein	Rattus norvegicus	80-87
17581952-13	2007	These results suggest that glycine 116 is required for C-terminal processing of GABARAP and that processing is essential for the localization of GABARAP and its functions as a trafficking protein.	Glycine	27-34	GABA type A receptor-associated protein	Rattus norvegicus	145-152
17511476-11	2007	Substitution of RGS7 Glu-73 and Asp-74 for the corresponding Ser and Gly residues (ED/SG mutation) of RGS9 diminished the DEP-Gbeta5 interaction.	Glycine	69-72	regulator of G protein signaling 9	Homo sapiens	102-106
27481943-12	2016	Determination of the x-ray structure of myristoylated NPHP3 peptide in complex with Unc119a reveals the molecular details of high affinity binding and suggests the importance of the residues at the +2 and +3 positions relative to the myristoylated glycine for high and low affinities.	Glycine	248-255	nephrocystin 3	Homo sapiens	54-59
17554001-6	2007	Interestingly, the VIAAT ortholog from Caenorhabditis elegans (UNC-47), a species lacking glycine transmission, also supports glycine exocytosis in the presence of GlyT2, and a point mutation of UNC-47 that abolishes GABA transmission in the worm confers glycine specificity.	Glycine	90-97	Vesicular GABA transporter	Caenorhabditis elegans	63-69
17554001-6	2007	Interestingly, the VIAAT ortholog from Caenorhabditis elegans (UNC-47), a species lacking glycine transmission, also supports glycine exocytosis in the presence of GlyT2, and a point mutation of UNC-47 that abolishes GABA transmission in the worm confers glycine specificity.	Glycine	126-133	Vesicular GABA transporter	Caenorhabditis elegans	63-69
17554001-6	2007	Interestingly, the VIAAT ortholog from Caenorhabditis elegans (UNC-47), a species lacking glycine transmission, also supports glycine exocytosis in the presence of GlyT2, and a point mutation of UNC-47 that abolishes GABA transmission in the worm confers glycine specificity.	Glycine	126-133	Vesicular GABA transporter	Caenorhabditis elegans	195-201
17554001-6	2007	Interestingly, the VIAAT ortholog from Caenorhabditis elegans (UNC-47), a species lacking glycine transmission, also supports glycine exocytosis in the presence of GlyT2, and a point mutation of UNC-47 that abolishes GABA transmission in the worm confers glycine specificity.	Glycine	126-133	Vesicular GABA transporter	Caenorhabditis elegans	63-69
17554001-6	2007	Interestingly, the VIAAT ortholog from Caenorhabditis elegans (UNC-47), a species lacking glycine transmission, also supports glycine exocytosis in the presence of GlyT2, and a point mutation of UNC-47 that abolishes GABA transmission in the worm confers glycine specificity.	Glycine	126-133	Vesicular GABA transporter	Caenorhabditis elegans	195-201
19478081-2	2009	As yet, the amino acid transport function of XT2 has only been experimentally supported by the urinary glycine loss observed in xt2 null mice.	Glycine	103-110	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	45-48
19478081-2	2009	As yet, the amino acid transport function of XT2 has only been experimentally supported by the urinary glycine loss observed in xt2 null mice.	Glycine	103-110	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	128-131
27553280-8	2016	The peptide/histidine transporter 1 (PHT1) was highly expressed in both myoblasts and myotubes, and co-administration of histidine inhibited Hyp-Gly-induced phosphorylation of p70S6K in myoblasts and myotubes.	Glycine	145-148	solute carrier family 15 member 4	Homo sapiens	4-35
27553280-8	2016	The peptide/histidine transporter 1 (PHT1) was highly expressed in both myoblasts and myotubes, and co-administration of histidine inhibited Hyp-Gly-induced phosphorylation of p70S6K in myoblasts and myotubes.	Glycine	145-148	solute carrier family 15 member 4	Homo sapiens	37-41
27553280-8	2016	The peptide/histidine transporter 1 (PHT1) was highly expressed in both myoblasts and myotubes, and co-administration of histidine inhibited Hyp-Gly-induced phosphorylation of p70S6K in myoblasts and myotubes.	Glycine	145-148	ribosomal protein S6 kinase B1	Homo sapiens	176-182
27296116-3	2016	In some cases GABA and glycine are co-released from the same neuron where they are co-packaged into synaptic vesicles by a shared vesicular inhibitory amino acid transporter, VIAAT (also called vGAT).	Glycine	23-30	solute carrier family 32 member 1	Homo sapiens	175-180
17486669-4	2007	Br(-)NPB-23-NH2 analogs in which each amino acid in positions 4, 5, 7, 8, 9, 10, 12 and 21 was replaced with alanine or glycine exhibited potent binding affinity comparable to the parent peptide.	Glycine	120-127	neuropeptide B	Homo sapiens	5-8
17445548-7	2007	After the glycine dose, the C(8) plus C(5) positions were enriched, whereas no significant enrichment at C(2) was found.	Glycine	10-17	complement C5	Homo sapiens	38-42
17445548-9	2007	To our knowledge, this is the first study to investigate (13)C enrichment from formate and glycine independently into the C(2) and C(8) positions of purine in the same subjects.	Glycine	91-98	complement C2	Homo sapiens	122-126
27296116-3	2016	In some cases GABA and glycine are co-released from the same neuron where they are co-packaged into synaptic vesicles by a shared vesicular inhibitory amino acid transporter, VIAAT (also called vGAT).	Glycine	23-30	solute carrier family 32 member 1	Homo sapiens	194-198
27296116-9	2016	The accumulated evidence challenges the hypothesis that vesicular phenotype is determined simply by the competition of inhibitory transmitter for VIAAT and instead suggest that the GABA/glycine balance in vesicles is dynamically regulated.	Glycine	186-193	solute carrier family 32 member 1	Homo sapiens	146-151
27358403-7	2016	The polymorphic nature of position 241 in both CELA3A (~4% Ala(241) alleles) and CELA3B (~2% Gly(241) alleles) points to individual variations in complex formation.	Glycine	93-96	chymotrypsin like elastase 3B	Homo sapiens	81-87
17382937-0	2007	A proline to glycine mutation in the Lck SH3-domain affects conformational sampling and increases ligand binding affinity.	Glycine	13-20	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	37-40
27143337-9	2016	Mutating position 86 in DRbeta1*01:01 from glycine to the valine residue found in DRbeta1*01:02 eliminated binding of both citrullinated alpha-enolase(11-25) and collagen(258-272), thereby recapitulating the peptide-binding profile of DRbeta1*01:02.	Glycine	43-50	enolase 1	Homo sapiens	137-150
17382937-2	2007	To test this hypothesis, we designed a mutant in which a proline in the RT-loop of the human Lck SH3-domain is replaced by glycine.	Glycine	123-130	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	93-96
26826093-0	2016	Japanese sporadic case of erythrokeratodermia variabilis caused by the connexin-30.3 (GJB4) mutation: Is Glycine 12 a mutational hotspot in the connexin family?	Glycine	105-112	gap junction protein beta 4	Homo sapiens	71-84
17374638-0	2007	Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation.	Glycine	55-58	fibrillin 1	Homo sapiens	17-28
17374639-1	2007	Gephyrin is a multifunctional protein contributing to molybdenum cofactor (Moco) synthesis and postsynaptic clustering of glycine and GABA(A) receptors.	Glycine	122-129	gephyrin	Homo sapiens	0-8
17388323-8	2007	Furthermore, the interaction energies (by MP2) of H2 with glycine, the glycine dimer, and imidazolium chloride amount to 2.78, 5.00, and 6.30 kJ mol-1, respectively.	Glycine	58-65	tryptase pseudogene 1	Homo sapiens	42-45
27264869-5	2016	Depletion of endogenous MDM2 in p53-deficient cells impairs serine/glycine metabolism, the NAD(+)/NADH ratio, and glutathione (GSH) recycling, impacting their redox state and tumorigenic potential.	Glycine	67-74	transformed mouse 3T3 cell double minute 2	Mus musculus	24-28
17388323-8	2007	Furthermore, the interaction energies (by MP2) of H2 with glycine, the glycine dimer, and imidazolium chloride amount to 2.78, 5.00, and 6.30 kJ mol-1, respectively.	Glycine	71-78	tryptase pseudogene 1	Homo sapiens	42-45
27264869-5	2016	Depletion of endogenous MDM2 in p53-deficient cells impairs serine/glycine metabolism, the NAD(+)/NADH ratio, and glutathione (GSH) recycling, impacting their redox state and tumorigenic potential.	Glycine	67-74	transformation related protein 53, pseudogene	Mus musculus	32-35
27358718-7	2016	The combined network shows that glycolytic enzymes are linked to miRs via p53, c-MYC, HIF1alpha, whereas the genes in serine, glycine and one carbon metabolism are regulated via the c-MYC, as well as other regulatory organization that cannot be observed by investigating individual miRs, TFs, and target genes.	Glycine	126-133	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	79-84
17360906-7	2007	In great contrast, activation of NR2A-mediated cell survival signaling with administration of either glycine alone or in the presence of NR2B antagonist significantly attenuated ischemic brain damage even when delivered 4.5 h after stroke onset.	Glycine	101-108	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	Mus musculus	33-37
17360906-8	2007	Together, the present work provides a molecular basis for the dual roles of NMDA receptors in promoting neuronal survival and mediating neuronal damage and suggests that selective enhancement of NR2A-containing NMDA receptor activation with glycine may constitute a promising therapy for stroke.	Glycine	241-248	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	Mus musculus	195-199
27358718-7	2016	The combined network shows that glycolytic enzymes are linked to miRs via p53, c-MYC, HIF1alpha, whereas the genes in serine, glycine and one carbon metabolism are regulated via the c-MYC, as well as other regulatory organization that cannot be observed by investigating individual miRs, TFs, and target genes.	Glycine	126-133	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	182-187
27064538-2	2016	We previously altered the enantioselectivity of tyrosyl-tRNA synthetase (TyrRS) by inserting the editing domain from phenylalanyl-tRNA synthetase (FRSed) between Gly 161 and Ile 162 in tyrosyl-tRNA synthetase (the editing domain hydrolyzes l-Tyr-tRNA but not d-Tyr-tRNA).	Glycine	162-165	tyrosyl-tRNA synthetase 1	Homo sapiens	48-71
17123829-7	2007	But, in the case of GST with Pro as the antepenultimate residue, the efficiency was significantly reduced when the penultimate residue was Gly or Thr.	Glycine	139-142	glutathione S-transferase	Triticum aestivum	20-23
27064538-2	2016	We previously altered the enantioselectivity of tyrosyl-tRNA synthetase (TyrRS) by inserting the editing domain from phenylalanyl-tRNA synthetase (FRSed) between Gly 161 and Ile 162 in tyrosyl-tRNA synthetase (the editing domain hydrolyzes l-Tyr-tRNA but not d-Tyr-tRNA).	Glycine	162-165	tyrosyl-tRNA synthetase 1	Homo sapiens	73-78
26972339-4	2016	Two independent glycine-to-arginine substitutions (G121R and G291R), both affecting key active site loops of PGM1, are found to induce regions of structural disorder, as evidenced by a nearly complete loss of electron density for as many as 23 aa.	Glycine	16-23	phosphoglucomutase 1	Homo sapiens	109-113
17366317-7	2007	The entire coding region (exons 3-13) of the Bhd gene was sequenced, and a guanine (nt106G) to adenine (nt106A) polymorphism was detected resulting in a glycine to arginine (G36R) substitution in both tumor-bearing animals.	Glycine	153-160	folliculin	Rattus norvegicus	45-48
26852340-6	2016	Four of the glycine water-soluble AAPCs (16, 18, 44 and 45) showed quantitative cleavage by LAP, resulting in the release of the highly cytotoxic parent drug, whereas partial cleavage (&lt;10-90%) was observed for other prodrugs (15, 17, 24, 38 and 39).	Glycine	12-19	LAP	Homo sapiens	92-95
17149711-2	2007	The G/T missense mutation occurred in exon 2 of PRKCG and results in a substitution of glycine by valine (G63V) in the evolutionarily highly conserved cysteine-rich region 1/C1 domain of PRKCG.	Glycine	87-94	protein kinase C gamma	Homo sapiens	48-53
17149711-2	2007	The G/T missense mutation occurred in exon 2 of PRKCG and results in a substitution of glycine by valine (G63V) in the evolutionarily highly conserved cysteine-rich region 1/C1 domain of PRKCG.	Glycine	87-94	protein kinase C gamma	Homo sapiens	187-192
26655825-4	2016	Here we investigated this question by examining the maturation and developmental refinement of GABA/glycinergic and glutamatergic synapses in the lateral superior olive (LSO), a binaural auditory brain stem nucleus, in KCC2-knockdown mice, in which GABA and glycine remain depolarizing.	Glycine	100-107	solute carrier family 12, member 5	Mus musculus	219-223
17726307-8	2007	In addition, 10 polymorphisms, including 1 non-glycine missense variant and 9 neutral polymorphisms, were detected in COL4A3/COL4A4.	Glycine	47-54	collagen type IV alpha 3 chain	Homo sapiens	118-124
27158326-4	2016	Results from Q-PCR and ELISA study showed that compareaded with control, TREM-1 is upregulated and TREM-2 is downregulated respectively in 4 and 8-week NASH model (TREM-1: p &lt; 0.001; TREM-2: p &lt; 0.001).Compared with HFO group, HFOG group with an extra 5% Glycine into the diet of NASH, we found that all model liver pathologic and serum indexes ameliorated in this group.	Glycine	261-268	triggering receptor expressed on myeloid cells 1	Homo sapiens	73-79
27158326-7	2016	Besides, using multiple-stepwise regression analysis, we found that the ameliorative effects of glycine in HFOG was mainly related to its counteraction of PC III, TREM-1 and upregulation of TREM-2.	Glycine	96-103	triggering receptor expressed on myeloid cells 1	Homo sapiens	163-169
17762207-1	2007	Glycine 2-methyl proline glutamate (G-2mPE) is a proline-modified analogue to the naturally existing N-terminal tripeptide glycine-proline-glutamate that is a cleaved product from insulin-like growth factor-1.	Glycine	123-131	insulin-like growth factor 1	Rattus norvegicus	180-208
27158326-10	2016	Glycine can relieve NASH by its anti-fibrosis effect, and this ameliorative effect is related to the expression change of TREM-1/2 to some extent.	Glycine	0-7	triggering receptor expressed on myeloid cells 1	Homo sapiens	122-128
26742748-2	2016	Special attention is paid to studies of the role of peptides Lys-Glu, Glu-Asp-Arg, and Ala-Glu-Asp-Gly in epigenetic regulation of irisin content.	Glycine	99-102	fibronectin type III domain containing 5	Homo sapiens	131-137
17075427-5	2006	The heterozygous, Gly/Arg variant of the IRS-1 gene was overrepresented and the homozygous, Gly/Gly variant was less frequent in male patients compared with male controls.	Glycine	18-21	insulin receptor substrate 1	Homo sapiens	41-46
17075427-9	2006	CONCLUSION: The polymorphism of the IRS-1 gene at codon 972, especially Gly/Arg variant, or the presence of the allele for Arg appears to be associated with occurrence of OSAS in male patients, whereas this polymorphism is not related to severity of OSAS.	Glycine	72-75	insulin receptor substrate 1	Homo sapiens	36-41
27132720-6	2016	Molecular docking study reveals the selectivity of these molecules towards ALDH1A1 (PDB: 4WP7) and important binding residues (GLY 125, 458; THR 129; TRP 178; TYR 297; PHE 171, 466; VAL 174, 460; MET 175; HIS 293 etc.)	Glycine	127-130	aldehyde dehydrogenase 1 family member A1	Homo sapiens	75-82
17035524-2	2006	We previously implicated mutations in the gene encoding glycyl-tRNA synthetase (GARS) as the cause of CMT2D and dSMA-V. GARS is a member of the family of aminoacyl-tRNA synthetases responsible for charging tRNA with cognate amino acids; GARS ligates glycine to tRNA(Gly).	Glycine	250-257	glycyl-tRNA synthetase 1	Homo sapiens	56-78
17035524-2	2006	We previously implicated mutations in the gene encoding glycyl-tRNA synthetase (GARS) as the cause of CMT2D and dSMA-V. GARS is a member of the family of aminoacyl-tRNA synthetases responsible for charging tRNA with cognate amino acids; GARS ligates glycine to tRNA(Gly).	Glycine	250-257	glycyl-tRNA synthetase 1	Homo sapiens	80-84
17035524-2	2006	We previously implicated mutations in the gene encoding glycyl-tRNA synthetase (GARS) as the cause of CMT2D and dSMA-V. GARS is a member of the family of aminoacyl-tRNA synthetases responsible for charging tRNA with cognate amino acids; GARS ligates glycine to tRNA(Gly).	Glycine	250-257	glycyl-tRNA synthetase 1	Homo sapiens	102-107
19593442-2	2009	GARS is ubiquitously expressed and may have functions in addition to its canonical role in protein synthesis through catalyzing the addition of glycine to cognate tRNAs.	Glycine	144-151	glycyl-tRNA synthetase 1	Homo sapiens	0-4
17035524-2	2006	We previously implicated mutations in the gene encoding glycyl-tRNA synthetase (GARS) as the cause of CMT2D and dSMA-V. GARS is a member of the family of aminoacyl-tRNA synthetases responsible for charging tRNA with cognate amino acids; GARS ligates glycine to tRNA(Gly).	Glycine	250-257	glycyl-tRNA synthetase 1	Homo sapiens	120-124
26476016-5	2016	Coimmunoprecipitation revealed that MARCH5 forms homodimers, and that substitution of Gly to Leu at the first putative GxxxG dimerization motif, but not the second, resulted in a loss of dimeric interaction.	Glycine	86-89	membrane associated ring-CH-type finger 5	Homo sapiens	36-42
17035524-2	2006	We previously implicated mutations in the gene encoding glycyl-tRNA synthetase (GARS) as the cause of CMT2D and dSMA-V. GARS is a member of the family of aminoacyl-tRNA synthetases responsible for charging tRNA with cognate amino acids; GARS ligates glycine to tRNA(Gly).	Glycine	250-257	glycyl-tRNA synthetase 1	Homo sapiens	120-124
16622593-3	2006	A new PRNP polymorphism encoding either glycine (G) or arginine (R) at codon 85 as well as eight previously reported polymorphisms at codons 101, 112, 127, 141, 146, 154, 171, and 189 in other sheep breeds were detected.	Glycine	40-47	major prion protein	Ovis aries	6-10
19366212-1	2009	Mammalian thioredoxin reductase (TR) contains a rare selenocysteine (Sec) residue in a conserved redox-active tetrapeptide of sequence Gly-Cys(1)-Sec(2)-Gly.	Glycine	135-138	peroxiredoxin 5	Homo sapiens	10-31
19366212-1	2009	Mammalian thioredoxin reductase (TR) contains a rare selenocysteine (Sec) residue in a conserved redox-active tetrapeptide of sequence Gly-Cys(1)-Sec(2)-Gly.	Glycine	135-138	peroxiredoxin 5	Homo sapiens	33-35
19433577-0	2009	The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine.	Glycine	4-11	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	48-61
26272487-5	2016	A new Asp to Gly homozygous mutation at position 173 of ADAMTS-13 sequence was identified in a family of Romanian origin, with some members affected by clinical signs of TTP.	Glycine	13-16	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	56-65
19433577-1	2009	Sarcosine is an amino acid involved in one-carbon metabolism and a promising therapy for schizophrenia because it enhances NMDA receptor (NMDAR) function by inhibiting glycine uptake.	Glycine	168-175	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	123-136
19433577-1	2009	Sarcosine is an amino acid involved in one-carbon metabolism and a promising therapy for schizophrenia because it enhances NMDA receptor (NMDAR) function by inhibiting glycine uptake.	Glycine	168-175	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	138-143
19433577-4	2009	We found that sarcosine is an NMDAR co-agonist at the glycine binding site.	Glycine	54-61	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	30-35
19433577-7	2009	The difference in desensitization probably accounts for rises in intracellular Ca(2+), as assessed by the fluorescent indicator fura-FF, being larger when NMDAR activation occurred with sarcosine than with glycine.	Glycine	206-213	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	155-160
19433577-8	2009	In addition, Ca(2+)-activated K(+) currents following NMDAR activation were larger with sarcosine than with glycine.	Glycine	108-115	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	54-59
26302655-1	2015	Glycine is the major inhibitory neurotransmitter in brainstem and spinal cord, whereas in hippocampus glycine exerts dual modulatory roles on strychnine-sensitive glycine receptors and on the strychnine-insensitive glycineB site of the N-methyl-D-aspartate receptor (NMDAR).	Glycine	102-109	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	236-265
19374720-1	2009	The neuronal glycine transporter GLYT2 belongs to the neurotransmitter:sodium:symporter (NSS) family and removes glycine from the synaptic cleft, thereby aiding the termination of the glycinergic signal and achieving the reloading of the presynaptic terminal.	Glycine	13-20	solute carrier family 6 member 5	Rattus norvegicus	33-38
19374720-7	2009	Coexpression of a Rab11 dominant negative mutant with recombinant GLYT2 impaired transporter trafficking and glycine transport.	Glycine	109-116	solute carrier family 6 member 5	Rattus norvegicus	66-71
16958854-4	2006	The importance of these 10 intramembranous proline residues for QacA-mediated transport function was determined by examining the functional effect of substituting these residues with glycine, alanine or serine.	Glycine	183-190	QacA	Staphylococcus aureus	64-68
26302655-1	2015	Glycine is the major inhibitory neurotransmitter in brainstem and spinal cord, whereas in hippocampus glycine exerts dual modulatory roles on strychnine-sensitive glycine receptors and on the strychnine-insensitive glycineB site of the N-methyl-D-aspartate receptor (NMDAR).	Glycine	102-109	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	267-272
19332109-1	2009	Converging evidence from pharmacological and molecular studies has led to the suggestion that inhibition of glycine transporter 1 (GlyT1) constitutes an effective means to boost N-methyl-d-aspartate receptor (NMDAR) activity by increasing the extra-cellular concentration of glycine in the vicinity of glutamatergic synapses.	Glycine	108-115	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	131-136
26302655-2	2015	In hippocampus, the synaptic availability of glycine is largely under control of glycine transporter 1 (GlyT1).	Glycine	45-52	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	81-102
19332109-1	2009	Converging evidence from pharmacological and molecular studies has led to the suggestion that inhibition of glycine transporter 1 (GlyT1) constitutes an effective means to boost N-methyl-d-aspartate receptor (NMDAR) activity by increasing the extra-cellular concentration of glycine in the vicinity of glutamatergic synapses.	Glycine	108-115	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	178-207
16489109-3	2006	tPA-induced contraction of rat aortic rings is inhibited by the Arg-Gly-Asp (RGD) peptide and by monoclonal anti-alphavbeta3 antibody.	Glycine	68-71	plasminogen activator, tissue type	Rattus norvegicus	0-3
26302655-2	2015	In hippocampus, the synaptic availability of glycine is largely under control of glycine transporter 1 (GlyT1).	Glycine	45-52	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	104-109
26302655-3	2015	Since epilepsy is a disorder of disrupted network homeostasis affecting the equilibrium of various neurotransmitters and neuromodulators, we hypothesized that changes in hippocampal GlyT1 expression and resulting disruption of glycine homeostasis might be implicated in the pathophysiology of epilepsy.	Glycine	227-234	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	182-187
19410451-2	2009	We describe herein the structure-activity relationships (SAR) of a structurally novel class of GlyT1 inhibitors following on a lead derived from high throughput screening, which shows good selectivity for GlyT1 and potent activity in elevating CSF levels of glycine.	Glycine	258-265	colony stimulating factor 2	Homo sapiens	244-247
16699824-1	2006	The proton coupled amino acid transporter PAT1 expressed in intestine, brain, and other organs accepts L- and D-proline, glycine, and L-alanine but also pharmaceutically active amino acid derivatives such as 3-amino-1-propanesulfonic acid, L-azetidine-2-carboxylic acid, and cis-4-hydroxy-D-proline as substrates.	Glycine	121-128	solute carrier family 36 member 1	Homo sapiens	42-46
26302655-6	2015	In support of a role of dysfunctional glycine signaling in the pathophysiology of epilepsy, both the genetic deletion of GlyT1 in hippocampus and the GlyT1 inhibitor LY2365109 increased seizure thresholds in mice.	Glycine	38-45	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	121-126
26302655-6	2015	In support of a role of dysfunctional glycine signaling in the pathophysiology of epilepsy, both the genetic deletion of GlyT1 in hippocampus and the GlyT1 inhibitor LY2365109 increased seizure thresholds in mice.	Glycine	38-45	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	150-155
19406877-4	2009	HERG-A653 is close to the "glycine hinge" implicated in K(+) channel opening, and is flanked by tyrosine 652 and phenylalanine 656, which contribute to the drug binding site.	Glycine	27-34	potassium voltage-gated channel subfamily H member 2	Homo sapiens	0-4
26585387-7	2015	Relief of hypersuccinylation by overexpressing the desuccinylase SIRT5 or supplementing glycine rescued mitochondrial dysfunctions, reversed BCL-2 accumulation, and slowed the oncogenic growth of hypersuccinylated IDH1(R132C)-harboring HT1080 cells.	Glycine	88-95	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	214-218
19289494-3	2009	Using the Cre/lox-conditional system, we show that the loss of PRMT1 in mouse embryonic fibroblasts (MEFs) leads to the loss of arginine methylation of substrates harboring a glycine-arginine rich motif, including Sam68 and MRE11.	Glycine	175-182	protein arginine N-methyltransferase 1	Mus musculus	63-68
19460156-9	2009	Incubation with D8AA in C6 glioma cells likewise produced D8NAGly; however, with significantly less efficacy leading to the hypothesis that FAAH-initiated AEA-released AA conjugation with glycine predominates in these cells.	Glycine	188-195	fatty acid amide hydrolase	Mus musculus	140-144
17081078-3	2006	Several putative molecular targets for treating cognition in schizophrenia show promise, such as treatments that act on the D(1) receptor of the dopamine system; the 5HT(1A), 5HT(2A), and 5HT(6), receptors of the serotonin system; and ampakines, Glycine/D-cycloserine, D-serine, and mGluR 2/3 agonists of the glutamatergic system.	Glycine	246-253	5-hydroxytryptamine receptor 1A	Homo sapiens	166-172
26219583-4	2015	In this study we reconstructed the evolutionary history of the glutathione S-transferase (GST) gene family from the soybean genome, and identified 72 GST duplicated gene pairs formed by a recent Glycine-specific WGD event occurring approximately 13 Ma.	Glycine	195-202	glutathione S-transferase	Glycine max	90-93
16800848-6	2006	Prior D1 receptor stimulation facilitated synaptic insertion of GluR1 in response to subsequent stimulation of synaptic NMDA receptors with glycine.	Glycine	140-147	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	64-69
19153190-0	2009	Glycine-extended gastrin inhibits apoptosis in Barrett"s oesophageal and oesophageal adenocarcinoma cells through JAK2/STAT3 activation.	Glycine	0-7	gastrin	Homo sapiens	17-24
19153190-4	2009	We have examined the effects of glycine-extended gastrin (G-Gly), an alternative product of progastrin processing on apoptosis in the QhERT Barrett"s oesophageal cell line and OE33 and BIC-1 OAC cells.	Glycine	32-39	gastrin	Homo sapiens	49-56
19244383-10	2009	Our simulations showed that the primary function of SHMT was to increase the rate by which the glycine-serine balance was reequilibrated after a perturbation.	Glycine	95-102	serine hydroxymethyltransferase 1	Homo sapiens	52-56
19155213-1	2009	Human liver peroxisomal alanine:glyoxylate aminotransferase (AGT) is a pyridoxal 5"-phosphate (PLP)-dependent enzyme that converts glyoxylate into glycine.	Glycine	147-154	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	24-59
26219583-4	2015	In this study we reconstructed the evolutionary history of the glutathione S-transferase (GST) gene family from the soybean genome, and identified 72 GST duplicated gene pairs formed by a recent Glycine-specific WGD event occurring approximately 13 Ma.	Glycine	195-202	glutathione S-transferase	Glycine max	150-153
19155213-1	2009	Human liver peroxisomal alanine:glyoxylate aminotransferase (AGT) is a pyridoxal 5"-phosphate (PLP)-dependent enzyme that converts glyoxylate into glycine.	Glycine	147-154	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	61-64
26512077-2	2016	Although viruses from raccoons do not efficiently bind the dog transferrin receptor (TfR) or infect dog cells, a single mutation changing an aspartic acid to a glycine at capsid (VP2) position 300 in the prototype raccoon CPV allows dog cell infection.	Glycine	160-167	VP2	Canine parvovirus	179-182
19158217-2	2009	Glycine decarboxylation through the glycine cleavage system (GCS) and glycine-serine transformation by serine hydroxymethyltransferase (SHMT) require pyridoxal 5"-phosphate (PLP; active form of vitamin B-6) as a coenzyme.	Glycine	0-7	serine hydroxymethyltransferase 1	Homo sapiens	136-140
19158217-2	2009	Glycine decarboxylation through the glycine cleavage system (GCS) and glycine-serine transformation by serine hydroxymethyltransferase (SHMT) require pyridoxal 5"-phosphate (PLP; active form of vitamin B-6) as a coenzyme.	Glycine	70-77	serine hydroxymethyltransferase 1	Homo sapiens	103-134
19158217-2	2009	Glycine decarboxylation through the glycine cleavage system (GCS) and glycine-serine transformation by serine hydroxymethyltransferase (SHMT) require pyridoxal 5"-phosphate (PLP; active form of vitamin B-6) as a coenzyme.	Glycine	70-77	serine hydroxymethyltransferase 1	Homo sapiens	136-140
26173648-9	2015	A homozygous mutation A1103G in exon 8 of DSG4 was identified in the patient, resulting in the substitution of an aspartic acid by glycine (D323G) and reduced DSG4 expression in the affected scalp epidermis.	Glycine	131-138	desmoglein 4	Homo sapiens	42-46
19270429-9	2009	These results suggest the therapeutic relevance of GlyT1 inhibitors for amelioration of motor ataxia in spinocerebellar atrophy by increasing the endogenous concentration of glycine near the glycine-recognition site of the NMDA receptor.	Glycine	174-181	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	51-56
26316425-4	2015	d-serine, synthesized from l-serine by serine racemase (Srr) in astrocytes, is an endogenous co-agonist for the NMDA receptor glycine site and can control NMDA receptor activity.	Glycine	126-133	serine racemase	Mus musculus	39-54
19178697-3	2009	TliA has four glycine-rich repeats (GGXGXD) in its C-terminus, which appear in many ABC transporter-secreted proteins.	Glycine	14-21	ABC transporter	Escherichia coli	84-99
26271732-1	2015	The hydration structure of sodium glycinate (Na(+)GL(-)) is probed by the Monte-Carlo multiple minimum (MCMM) method combined with quantum mechanical (QM) calculations at the MP2/6-311++G(d,p) level.	Glycine	27-43	tryptase pseudogene 1	Homo sapiens	175-178
18449897-3	2009	In this study, we aimed to investigate the relationship of the Serine/Glycine polymorphism of the DRD3 gene with therapeutic response to clozapine treatment between Turkish schizophrenia patients (N = 92) and healthy controls (N = 100).	Glycine	70-77	dopamine receptor D3	Homo sapiens	98-102
25784602-3	2015	Because glycine is an obligatory co-agonist that works cooperatively with glutamate to promote opening of the ion channel, one prominent strategy to promote NMDA receptor-mediated neurotransmission involves inhibition of the glycine type 1 transporter (GlyT1).	Glycine	8-15	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	225-251
18449897-5	2009	Our results suggest that an association between the Ser/Gly polymorphism of DRD3 gene and response to clozapine in Turkish schizophrenia patients is unlikely to exist.	Glycine	56-59	dopamine receptor D3	Homo sapiens	76-80
25784602-3	2015	Because glycine is an obligatory co-agonist that works cooperatively with glutamate to promote opening of the ion channel, one prominent strategy to promote NMDA receptor-mediated neurotransmission involves inhibition of the glycine type 1 transporter (GlyT1).	Glycine	8-15	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	253-258
18990687-4	2009	Point mutations in the glycine binding domain of the NR1-1a subunit were generated: D732A, a mutation that results in an approximately 3 x 10(4) decrease in glycine binding affinity; D732E, a conservative change; and D723A, a residue in the same NR1-1a domain that has no effect on glycine binding affinity.	Glycine	23-30	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	53-56
26022122-8	2015	The structure and structure-based mutational analyses suggest that either the last five residues at the extreme C-terminus of Cdc14p (residues 547-551; Gly-Ser-Ile-Lys-Lys) or adjacent residues with similar sequence (residues 540-544; Gly-Gly-Ile-Arg-Lys) can bind to the NLS-binding site of Kap121p, with two residues (Ile in the middle and Lys at the end of the five residues) of Cdc14p making key contributions to the binding specificity.	Glycine	235-238	phosphoprotein phosphatase CDC14	Saccharomyces cerevisiae S288C	126-132
18990687-4	2009	Point mutations in the glycine binding domain of the NR1-1a subunit were generated: D732A, a mutation that results in an approximately 3 x 10(4) decrease in glycine binding affinity; D732E, a conservative change; and D723A, a residue in the same NR1-1a domain that has no effect on glycine binding affinity.	Glycine	157-164	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	53-56
18990687-4	2009	Point mutations in the glycine binding domain of the NR1-1a subunit were generated: D732A, a mutation that results in an approximately 3 x 10(4) decrease in glycine binding affinity; D732E, a conservative change; and D723A, a residue in the same NR1-1a domain that has no effect on glycine binding affinity.	Glycine	157-164	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	53-56
26022122-8	2015	The structure and structure-based mutational analyses suggest that either the last five residues at the extreme C-terminus of Cdc14p (residues 547-551; Gly-Ser-Ile-Lys-Lys) or adjacent residues with similar sequence (residues 540-544; Gly-Gly-Ile-Arg-Lys) can bind to the NLS-binding site of Kap121p, with two residues (Ile in the middle and Lys at the end of the five residues) of Cdc14p making key contributions to the binding specificity.	Glycine	235-238	phosphoprotein phosphatase CDC14	Saccharomyces cerevisiae S288C	126-132
26046984-12	2015	Coexpression of USP30 similarly increased Igly-gly in PEPT1 expressing oocytes.	Glycine	43-46	ubiquitin specific peptidase 30 L homeolog	Xenopus laevis	16-21
18805949-4	2009	Upon transfer to normal air, the go1 mutant became necrotic within 7 d and plants died within 15 d. Providing [1-14C]glycolate to leaf tissue of go1 mutants in darkness confirmed that the substrate is inefficiently converted to 14CO2, but both wild-type and GO-deficient mutant seedlings metabolized [1-14C]glycine similarly to produce [14C]serine and 14CO2 in a 1:1 ratio, suggesting that the photorespiratory pathway is otherwise normal in the mutant.	Glycine	307-314	glycolate oxidase 1	Zea mays	33-36
25788713-3	2015	Our laboratory has developed two transgenic mouse lines that exhibit contrasting NMDAR activity based on the availability of the glycine modulatory site (GMS) agonists d-serine and glycine.	Glycine	129-136	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	81-86
25788713-3	2015	Our laboratory has developed two transgenic mouse lines that exhibit contrasting NMDAR activity based on the availability of the glycine modulatory site (GMS) agonists d-serine and glycine.	Glycine	181-188	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	81-86
18758757-1	2009	RATIONALE: Inhibition of the glycine transporter 1 (GlyT1) activity increases extra-cellular glycine availability in the CNS.	Glycine	29-36	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	52-57
24953863-8	2015	Furthermore, liquid chromatography coupled with tandem mass spectrometry analysis demonstrates that proline residues of the recombinant human collagen alpha1(III) chain were hydroxylated in the X or Y positions of Gly-X-Y triplets.	Glycine	214-217	collagen type III alpha 1 chain	Homo sapiens	142-168
18758757-2	2009	At glutamatergic synapses, increased binding to the glycine-B site located in the N-methyl-D-aspartate receptor (NMDAR) can enhance neurotransmission via NMDARs.	Glycine	52-59	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	82-111
18758757-2	2009	At glutamatergic synapses, increased binding to the glycine-B site located in the N-methyl-D-aspartate receptor (NMDAR) can enhance neurotransmission via NMDARs.	Glycine	52-59	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	113-118
25707447-1	2015	A novel CBr4-mediated dehydrogenative Povarov/aromatization tandem reaction of glycine derivatives with alkenes, leading to complex quinoline derivatives, and a CBr4-mediated dehydrogenative C-H functionalization of N-aryl tetrahydroisoquinolines with nucleophiles to form C-C and C-P bonds are reported.	Glycine	79-86	carbonyl reductase 4	Homo sapiens	8-12
19006282-7	2008	This is in contrast to that found for Co2+ interacting with glycine in which the most stable structure has the amino acid in its zwitterionic form, which points out the importance of the side chain.	Glycine	60-67	complement C2	Homo sapiens	38-41
18798526-3	2008	The concentration of glycine at synapses is mainly controlled by two sodium and chloride dependent transporters, GLYT1 and GLYT2, proteins that display a complementary distribution and activity in the nervous system.	Glycine	21-28	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	113-118
25637053-7	2015	Accordingly, the shedding of the transferrin receptor-2 variant G679A, mutated in the Arginine-Glycine-Aspartic acid motif and unable to bind diferric transferrin, is not modulated by the ligand.	Glycine	95-102	transferrin receptor 2	Homo sapiens	33-55
18798526-3	2008	The concentration of glycine at synapses is mainly controlled by two sodium and chloride dependent transporters, GLYT1 and GLYT2, proteins that display a complementary distribution and activity in the nervous system.	Glycine	21-28	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	123-128
25852471-11	2015	At the molecular level, several metabolic intermediates that are connected to glycolysis, glycine, or cysteine metabolism are deregulated in TRIM32 knockout mice brain tissue.	Glycine	90-97	tripartite motif-containing 32	Mus musculus	141-147
18842710-4	2008	This virus (the 51g mutant) contains a cysteine-to-glycine mutation (51st amino acid) in the C(3)HC(4) zinc RING finger of bICP0.	Glycine	51-58	ubiquitin E3 ligase ICP0	Bovine alphaherpesvirus 1	123-128
18805436-6	2008	Forebrain synaptic glycine and d-serine levels are regulated by the Glycine Transporter-1 (GlyT1) and the arginine-serine-cysteine transporter-1 (Asc-1), respectively; in addition to D-serine metabolism by D-Amino Acid Oxidase (DAAO).	Glycine	19-26	D-amino acid oxidase	Homo sapiens	206-226
18805436-6	2008	Forebrain synaptic glycine and d-serine levels are regulated by the Glycine Transporter-1 (GlyT1) and the arginine-serine-cysteine transporter-1 (Asc-1), respectively; in addition to D-serine metabolism by D-Amino Acid Oxidase (DAAO).	Glycine	19-26	D-amino acid oxidase	Homo sapiens	228-232
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	D-amino acid oxidase	Homo sapiens	93-113
18703116-9	2008	The Mantel-Haenszel pooled OR for SCZ among carriers of the DRD3 Ser9Gly homozygosity (Ser/Ser homozygotes and Gly/Gly homozygotes) of the nine Japanese studies was 1.16 (95% CI 0.97-1.39), pointing to a non-significant effect of the DRD3 Ser9Gly homozygosity as a risk factor for SCZ.	Glycine	69-72	dopamine receptor D3	Homo sapiens	60-64
25634381-7	2015	The crystal structures of these compounds bound to ALDH1A1 demonstrate that they bind within the aldehyde binding pocket of ALDH1A1 and exploit the presence of a unique glycine residue to achieve their selectivity.	Glycine	169-176	aldehyde dehydrogenase 1 family member A1	Homo sapiens	51-58
18703116-9	2008	The Mantel-Haenszel pooled OR for SCZ among carriers of the DRD3 Ser9Gly homozygosity (Ser/Ser homozygotes and Gly/Gly homozygotes) of the nine Japanese studies was 1.16 (95% CI 0.97-1.39), pointing to a non-significant effect of the DRD3 Ser9Gly homozygosity as a risk factor for SCZ.	Glycine	69-72	dopamine receptor D3	Homo sapiens	234-238
18728013-4	2008	EphA1 transmembrane segments associate in a right-handed parallel alpha-helical bundle, region (544-569)(2), through the N-terminal glycine zipper motif A(550)X(3)G(554)X(3)G(558).	Glycine	132-139	EPH receptor A1	Homo sapiens	0-5
25634381-7	2015	The crystal structures of these compounds bound to ALDH1A1 demonstrate that they bind within the aldehyde binding pocket of ALDH1A1 and exploit the presence of a unique glycine residue to achieve their selectivity.	Glycine	169-176	aldehyde dehydrogenase 1 family member A1	Homo sapiens	124-131
18619974-9	2008	Despite mimetic substitutions, including a glycine-to-(d)-proline change, the gp120 conformation induced by CD4M47 was as close or closer to the conformation induced by CD4 as the one induced by the parent CD4M33.	Glycine	43-50	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	78-83
25699100-8	2015	Notably, GP IIb/IIIa expression was associated with the vulnerability index and necrotic center/fiber cap ratio (P&lt;0.05), and contrast video intensity from adhered cyclic Arg-Gly-Asp-modified MBs (MB-cRGDs) was correlated with GP IIb/IIIa expression on the plaque surface (P&lt;0.05).	Glycine	178-181	integrin alpha 2b	Mus musculus	9-15
18695510-2	2008	The effective synaptic concentrations of glycine are regulated by at least two transporters: glycine transporter 1 and glycine transporter 2.	Glycine	41-48	solute carrier family 6 member 5	Rattus norvegicus	119-140
18711142-1	2008	Coassembly of the glycine-binding NMDA receptor subunits NR1 and NR3A results in excitatory glycine receptors of low efficacy.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	65-69
25651059-7	2015	The triple helix crosses the junction of blades I and II at a 45  angle to the symmetry axis of the HPX domain, placing the scissile Gly~Ile bond near the HPX domain and shifted ~25 A from MMP-1 complexes.	Glycine	133-136	matrix metallopeptidase 1	Homo sapiens	189-194
18711142-2	2008	Here, we report that micromolar concentrations of the divalent cation Zn(2+) produce a 10-fold potentiation of NR1/NR3A receptor responses, which resembles that seen upon antagonizing glycine binding to the NR1 subunit.	Glycine	184-191	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	115-119
18711142-5	2008	Point mutations in the NR1 and NR3A glycine-binding sites revealed that both the potentiating and agonistic effects of Zn(2+) are mediated by the ligand-binding domain of the NR1 subunit.	Glycine	36-43	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	31-35
18713466-0	2008	Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure.	Glycine	71-78	cysteine and glycine-rich protein 2	Mus musculus	33-38
25468444-3	2015	IGFBP-1 and IGFBP-2 have a C-terminal Arg-Gly-Asp (RGD) sequence, and IGFBP-1 has been shown by others to stimulate migration through binding of its RGD sequence to alpha5beta1 integrin.	Glycine	42-45	insulin like growth factor binding protein 1	Homo sapiens	0-7
18713466-0	2008	Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure.	Glycine	71-78	cysteine and glycine-rich protein 2	Mus musculus	103-107
26875494-4	2015	The P. putida ThiO is unique in that glycine is its preferred substrate, which differs markedly from the B. subtilis and G. kaustophilus enzymes that use D-proline as the preferred substrate.	Glycine	37-44	glycine oxidase ThiO	Pseudomonas putida KT2440	14-18
18613721-7	2008	In previous studies HSMD (and HS Monte CarloHSMC) has been extended systematically to systems of increasing complexity, where the most recent is the seven-residue mobile loop, 304-310 (Gly-His-Gly-Ala-Gly-Gly-Ser) of the enzyme porcine pancreatic alpha-amylase modeled by the AMBER force field and AMBER with the implicit solvation GB/SA (paper I, Cheluvaraja, S.; Meirovitch, H. J. Chem.	Glycine	185-188	amylase alpha 2A	Homo sapiens	236-260
18636091-2	2008	Using ligand binding assays, crystallographic analysis, and all atom MD simulations, we investigate mechanisms underlying the binding by NR3A and NR3B of glycine and D-serine, which are candidate neurotransmitters for NMDA receptors containing NR3 subunits.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	137-141
26544978-10	2015	This mix is different in nonstressed conditions, containing substantially increased amounts of the nonessential amino acids glutamine, alanine, glycine and (hydroxy)proline.	Glycine	144-151	Mix paired-like homeobox	Homo sapiens	5-8
19241594-1	2008	Protein P34 (Gly m Bd 30K) is the immunodominant allergen in soybean (Glycine max L.).	Glycine	13-16	P34 probable thiol protease	Glycine max	8-11
25551757-6	2014	The cysteine residues involved in the formation of the disulfide bridges in CD9 EC2 were all essential for inhibitory activity but a conserved glycine residue in the tetraspanin-defining "CCG" motif was not.	Glycine	143-150	transcription factor 15	Homo sapiens	80-83
18448867-3	2008	Glycine transporter (GlyT)1, present in glial cells, and GlyT2, located in neurons, play roles in modulating glycinergic neurotransmission by clearing synaptically released glycine or supplying glycine to the neurons and thus could modify pain signal transmission in the spinal cord.	Glycine	109-116	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	0-27
18448867-3	2008	Glycine transporter (GlyT)1, present in glial cells, and GlyT2, located in neurons, play roles in modulating glycinergic neurotransmission by clearing synaptically released glycine or supplying glycine to the neurons and thus could modify pain signal transmission in the spinal cord.	Glycine	109-116	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	57-62
18448867-3	2008	Glycine transporter (GlyT)1, present in glial cells, and GlyT2, located in neurons, play roles in modulating glycinergic neurotransmission by clearing synaptically released glycine or supplying glycine to the neurons and thus could modify pain signal transmission in the spinal cord.	Glycine	173-180	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	0-27
18448867-3	2008	Glycine transporter (GlyT)1, present in glial cells, and GlyT2, located in neurons, play roles in modulating glycinergic neurotransmission by clearing synaptically released glycine or supplying glycine to the neurons and thus could modify pain signal transmission in the spinal cord.	Glycine	173-180	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	57-62
18501631-2	2008	The influence of N-terminal part (Q103-P138) truncation of human Fas ligand extracellular domain (hFasLECD) on the expression of N-terminal FLAG-(Gly)(5)-tagged hFasLECD (NFG5-hFasLECD) with partial N-glycosylation-sites deletion in Pichia pastoris was investigated.	Glycine	146-149	Fas ligand	Homo sapiens	65-75
16835863-1	2006	Costello syndrome (CS) is a rare congenital condition caused by heterozygous de novo missense mutations affecting the codon for glycine 12 or 13 of the HRAS gene.	Glycine	128-135	HRas proto-oncogene, GTPase	Homo sapiens	152-156
25486018-12	2014	This suggests that PPARalpha has an important role in modulating serine, glycine and arginine de novo synthesis.	Glycine	73-80	peroxisome proliferator activated receptor alpha	Rattus norvegicus	19-28
16772843-2	2006	Screening for MEN 2B revealed a polymorphism of the RET proto-oncogene at codon 691 with a glycine to serine conversion.	Glycine	91-98	ret proto-oncogene	Homo sapiens	14-20
25168514-3	2014	GARS is a member of the ubiquitously expressed aminoacyl-tRNA synthetase (ARS) family and is responsible for charging tRNA with glycine.	Glycine	128-135	glycyl-tRNA synthetase 1	Homo sapiens	0-4
16772843-2	2006	Screening for MEN 2B revealed a polymorphism of the RET proto-oncogene at codon 691 with a glycine to serine conversion.	Glycine	91-98	ret proto-oncogene	Homo sapiens	52-55
18628682-1	2008	OBJECTIVES: Vesicle-associated membrane proteins 2 and 3 (VAMP2 and VAMP3) are required for the release of D-serine, a competitive agonist of the neurotransmitter glycine at the glutamatergic N-methyl-D-aspartate receptors.	Glycine	163-170	vesicle associated membrane protein 3	Homo sapiens	68-73
17945380-2	2008	Among the mitochondrial proteins involved in glycine oxidation, the L, P and T proteins of glycine decarboxylase complex (GDC) and serine hydroxymethyltransferase (SHMT) were present, while the H protein of GDC was undetectable.	Glycine	45-52	serine hydroxymethyltransferase	Zea mays	131-162
17945380-2	2008	Among the mitochondrial proteins involved in glycine oxidation, the L, P and T proteins of glycine decarboxylase complex (GDC) and serine hydroxymethyltransferase (SHMT) were present, while the H protein of GDC was undetectable.	Glycine	45-52	serine hydroxymethyltransferase	Zea mays	164-168
25164808-8	2014	The cell line expressing cytosolic FPGS required exogenous glycine but not thymidine or purine, whereas cells expressing the mitochondrial isoform required exogenous thymidine and purine but not glycine for optimal growth and survival.	Glycine	59-66	folylpolyglutamate synthase	Homo sapiens	35-39
18499099-0	2008	Glycine increases mRNA adiponectin and diminishes pro-inflammatory adipokines expression in 3T3-L1 cells.	Glycine	0-7	adiponectin, C1Q and collagen domain containing	Mus musculus	23-34
18499099-9	2008	We demonstrated that when 3T3-L1 cells were treated with glycine, IL-6, resistin and TNF-alpha mRNA expression was decreased, but surprisingly adiponectin and PPAR-gamma were up-regulated.	Glycine	57-64	resistin	Mus musculus	72-80
18499099-9	2008	We demonstrated that when 3T3-L1 cells were treated with glycine, IL-6, resistin and TNF-alpha mRNA expression was decreased, but surprisingly adiponectin and PPAR-gamma were up-regulated.	Glycine	57-64	adiponectin, C1Q and collagen domain containing	Mus musculus	143-154
18499099-11	2008	These results show that glycine improves the pro-inflammatory profile and up-regulates adiponectin gene expression.	Glycine	24-31	adiponectin, C1Q and collagen domain containing	Mus musculus	87-98
16722632-4	2006	Peptide analogues containing C(alpha alpha)-dialkylated glycine (Aaa1, 1) or C(alpha)-alkylated glycine (Aaa2, 2) amino acid residues showed antitumor activity against melanoma, larynx carcinoma, colon carcinomas, and colon metastasis cell lines in vitro.	Glycine	96-103	AAA2	Homo sapiens	105-109
16670331-4	2006	With mouse MD-2 mutants, we show in this study that Gly(59) was found to be a novel critical amino acid for LPS binding outside the region 119-132.	Glycine	52-55	lymphocyte antigen 96	Mus musculus	11-15
16670331-7	2006	MD-2 mutants substituting alanine for Phe(126) or Gly(129) impaired LPS-induced TLR4 clustering, but not LPS binding to TLR4/MD-2, demonstrating that ligand-induced receptor clustering is differentially regulated by MD-2 from ligand binding.	Glycine	50-53	lymphocyte antigen 96	Mus musculus	0-4
25234600-8	2014	When the PEST sequence (Glu(31)-Cys(46)) was inserted into the L-type GATA-6 without Arg(13)-Gly(101), the resultant recombinant protein showed significantly higher transcriptional activity, while the construct with an unrelated sequence exhibited lower activity.	Glycine	93-96	GATA binding protein 6	Homo sapiens	70-76
16337282-11	2006	The site of trypsin cleavage was identified in the deduced amino acid sequence of muB by determining the amino-terminal sequences of phi proteins: between arginine 582 and glycine 583.	Glycine	172-179	ubiquitin like 3	Homo sapiens	82-85
16611982-0	2006	Cdc37 interacts with the glycine-rich loop of Hsp90 client kinases.	Glycine	25-32	heat shock protein 90 alpha family class A member 1	Homo sapiens	46-51
16611982-2	2006	Phage display technology and liquid chromatography-tandem mass spectrometry (which identifies a total of 33 proteins) consistently identify a unique sequence, GXFG, as a Cdc37-interacting motif that occurs in the canonical glycine-rich loop (GXGXXG) of protein kinases, regardless of their dependence on Hsp90 or Cdc37.	Glycine	223-230	heat shock protein 90 alpha family class A member 1	Homo sapiens	304-309
18378852-8	2008	Mutations at Gly-537 account for 4 of 5 HIF2A mutations associated with erythrocytosis.	Glycine	13-16	endothelial PAS domain protein 1	Homo sapiens	40-45
18331477-0	2008	Sustained saturating level of glycine induces changes in NR2B-containing-NMDA receptor localization in the CA1 region of the hippocampus.	Glycine	30-37	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	57-61
18331477-0	2008	Sustained saturating level of glycine induces changes in NR2B-containing-NMDA receptor localization in the CA1 region of the hippocampus.	Glycine	30-37	carbonic anhydrase 1	Mus musculus	107-110
18331477-4	2008	Blockage of GlyT1 enhances NMDAR function by controlling ambient glycine concentrations.	Glycine	65-72	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	12-17
18331477-4	2008	Blockage of GlyT1 enhances NMDAR function by controlling ambient glycine concentrations.	Glycine	65-72	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	27-32
18331477-6	2008	In this study, we report that the glycine modulatory site of the NMDAR at CA1 synapses is saturated in GlyT1+/- but not in wild-type (WT) mice.	Glycine	34-41	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	65-70
24530133-6	2014	RESULTS: We showed that the FAAH inhibitor PF-3845 reduced experimental TNBS-induced colitis in mice and its anti-inflammatory action is associated with altering the levels of selected biolipids (arachidonic and oleic acid derivatives, prostaglandins and biolipids containing glycine in the mouse colon).	Glycine	276-283	fatty acid amide hydrolase	Mus musculus	28-32
18331477-6	2008	In this study, we report that the glycine modulatory site of the NMDAR at CA1 synapses is saturated in GlyT1+/- but not in wild-type (WT) mice.	Glycine	34-41	carbonic anhydrase 1	Mus musculus	74-77
18331477-6	2008	In this study, we report that the glycine modulatory site of the NMDAR at CA1 synapses is saturated in GlyT1+/- but not in wild-type (WT) mice.	Glycine	34-41	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	103-108
18331477-7	2008	We also found that the effect of ifenprodil, a highly selective NR2B-containing-NMDAR antagonist, is significantly reduced at CA1 synapses in GlyT1+/- compared to WT mice while immunoblotting experiments do not show significant differences for NR1, NR2A-B-C-D subunits in both types of mice, suggesting alteration in NR2B-containing-NMDAR localization under a state of chronic saturating level of endogenous glycine.	Glycine	408-415	carbonic anhydrase 1	Mus musculus	126-129
18331477-7	2008	We also found that the effect of ifenprodil, a highly selective NR2B-containing-NMDAR antagonist, is significantly reduced at CA1 synapses in GlyT1+/- compared to WT mice while immunoblotting experiments do not show significant differences for NR1, NR2A-B-C-D subunits in both types of mice, suggesting alteration in NR2B-containing-NMDAR localization under a state of chronic saturating level of endogenous glycine.	Glycine	408-415	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	142-147
16618767-5	2006	The inhibition was shown to be concentration, NADPH, and time dependent and involved an attack on the reduced COOH-terminal -Cys-Sec-Gly active site of TrxR.	Glycine	133-136	peroxiredoxin 5	Homo sapiens	152-156
16513329-1	2006	BACKGROUND: A polymorphic site in the gene encoding the dopamine 3 receptor (DRD3) resulting in a serine (Ser) into glycine (Gly) substitution has been shown to affect dopamine binding affinity, and may contribute to individual differences in susceptibility to antipsychotic-induced tardive dyskinesia (TD).	Glycine	116-123	dopamine receptor D3	Homo sapiens	77-81
16513329-1	2006	BACKGROUND: A polymorphic site in the gene encoding the dopamine 3 receptor (DRD3) resulting in a serine (Ser) into glycine (Gly) substitution has been shown to affect dopamine binding affinity, and may contribute to individual differences in susceptibility to antipsychotic-induced tardive dyskinesia (TD).	Glycine	125-128	dopamine receptor D3	Homo sapiens	77-81
18362146-9	2008	Blocking of integrins with an Arg-Gly-Asp-containing peptide counteracted the matrix contacts necessary to initiate the uPAR-dependent cytoskeletal rearrangements, whereas inactivation of the Rac signaling pathway in all cases suppressed the occurrence of the same events.	Glycine	34-37	plasminogen activator, urokinase receptor	Homo sapiens	120-124
24990691-1	2014	The high glycine/tyrosine type II keratin protein 6.1 (KAP6.1) is a member of the keratin-associated protein family, which is restricted to cells in hair follicles and is associated with fiber diameter and fiber curvature in Merino sheep.	Glycine	9-16	keratin-associated protein 6-1	Ovis aries	55-61
18321862-2	2008	Like ubiquitin and other ubiquitin-like proteins, Ufm1 is synthesized as a precursor that needs to be processed to expose the conserved C-terminal glycine prior to its conjugation to target proteins.	Glycine	147-154	ubiquitin-fold modifier 1	Mus musculus	50-54
24915645-8	2014	In addition, our findings underscore the potential utility of using the glycine modulatory site agonist D-serine to treat disorders that exhibit Arc and dendritic spine dysregulation as a consequence of NMDAR hypofunction, such as schizophrenia.	Glycine	72-79	activity regulated cytoskeletal-associated protein	Mus musculus	145-148
18292292-7	2008	By engineering the surface of erythrocytes with covalently coupled cyclic Arg-Gly-Asp (RGD) peptides--mimicking lactadherin opsonization--we could induce phagocytosis by angiogenic endothelial cells both in vitro and in vivo.	Glycine	78-81	milk fat globule EGF and factor V/VIII domain containing	Mus musculus	112-123
18295462-8	2008	EGF induced an increase in uptake of (14)C-glycylsarcosine ([(14)C]-Gly-Sar), accompanied by an increase in transcellular electrical resistance, total cell protein, alkaline phosphatase activity and cell density.	Glycine	68-71	epidermal growth factor	Sus scrofa	0-3
18295462-9	2008	The increase in uptake of [(14)C]-Gly-Sar was maximal when cells were cultured in the presence of EGF throughout the culture period of 10 days.	Glycine	34-37	epidermal growth factor	Sus scrofa	98-101
16609991-0	2006	Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells.	Glycine	0-7	gastrin	Homo sapiens	17-24
16609991-0	2006	Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells.	Glycine	0-7	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Homo sapiens	92-121
24915645-8	2014	In addition, our findings underscore the potential utility of using the glycine modulatory site agonist D-serine to treat disorders that exhibit Arc and dendritic spine dysregulation as a consequence of NMDAR hypofunction, such as schizophrenia.	Glycine	72-79	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	203-208
16326905-8	2006	Mutation of the Pro or Gly of the Pro-Ala-Gly motif to Ala abolished KCNQ1 function and introduction of Gly in front of the Ala-mutations partially recovered channel function, suggesting that flexibility at the PAG is important for channel activation.	Glycine	23-26	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	69-74
25221477-10	2014	The postsynaptic action of GABA and glycine depends on the intracellular concentration of chloride ions which is regulated by a protein in the plasma membrane, the K(+)-Cl(-) cotransporter (KCC2) extruding both K(+) and Cl(-) ions.	Glycine	36-43	solute carrier family 12 member 5	Rattus norvegicus	190-194
16326905-8	2006	Mutation of the Pro or Gly of the Pro-Ala-Gly motif to Ala abolished KCNQ1 function and introduction of Gly in front of the Ala-mutations partially recovered channel function, suggesting that flexibility at the PAG is important for channel activation.	Glycine	42-45	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	69-74
16169610-1	2006	Glycine-extended gastrin (G-Gly) is an end product of processing of the progastrin precursor peptide that has a different spectrum of activity to amidated gastrin.	Glycine	0-7	gastrin	Homo sapiens	75-82
18279665-2	2008	Regarding evolutionary aspects, the tRNA(Gly)/GlyRS system is a special case.	Glycine	41-44	glycyl-tRNA synthetase 1	Homo sapiens	46-51
18227065-10	2008	In VLCAD, these residues are glycines (Gly-175 and Gly-178), allowing the binding channel to extend for an additional 12A and permitting substrate acyl chain lengths as long as 24 carbons to bind.	Glycine	29-37	acyl-CoA dehydrogenase very long chain	Homo sapiens	3-8
18227065-10	2008	In VLCAD, these residues are glycines (Gly-175 and Gly-178), allowing the binding channel to extend for an additional 12A and permitting substrate acyl chain lengths as long as 24 carbons to bind.	Glycine	39-42	acyl-CoA dehydrogenase very long chain	Homo sapiens	3-8
18227065-10	2008	In VLCAD, these residues are glycines (Gly-175 and Gly-178), allowing the binding channel to extend for an additional 12A and permitting substrate acyl chain lengths as long as 24 carbons to bind.	Glycine	51-54	acyl-CoA dehydrogenase very long chain	Homo sapiens	3-8
25221477-11	2014	Absence or reduction of KCC2 expression leads to a depolarizing action of GABA and glycine and a marked reduction in the strength of postsynaptic inhibition.	Glycine	83-90	solute carrier family 12 member 5	Rattus norvegicus	24-28
16513844-3	2006	Here, we show that the heterogenous ribonucleoprotein A18 (hnRNP A18) RNA Binding Domain (RBD) and the arginine, glycine (RGG) rich domain can bind TRX 3"-untranslated region (3"-UTR) independently but both domains are required for maximal binding.	Glycine	113-120	thioredoxin	Homo sapiens	148-151
25002256-2	2014	GST catalyzes the selective S(N)Ar reaction between an N-terminal glutathione (GSH, gamma-Glu-Cys-Gly) tag and a C-terminal perfluoroaryl-modified cysteine on the same polypeptide chain.	Glycine	98-101	glutathione S-transferase kappa 1	Homo sapiens	0-3
16405520-7	2006	RESULTS: In vitro adhesion assays revealed that VWF is able to promote a dose-dependent adhesion of B16-BL6 cells via its Arg-Gly-Asp (RGD) sequence.	Glycine	126-129	Von Willebrand factor	Mus musculus	48-51
18262473-2	2008	Elements of the glycinergic phenotype include the membrane-bound glycine transporters (GLYT1 and GLYT2), which remove glycine from the synaptic cleft, and the vesicular inhibitory amino acid transporter (VIAAT or VGAT), which sequesters both glycine and GABA into synaptic vesicles.	Glycine	16-23	solute carrier family 6 member 9 L homeolog	Xenopus laevis	87-92
18262473-2	2008	Elements of the glycinergic phenotype include the membrane-bound glycine transporters (GLYT1 and GLYT2), which remove glycine from the synaptic cleft, and the vesicular inhibitory amino acid transporter (VIAAT or VGAT), which sequesters both glycine and GABA into synaptic vesicles.	Glycine	65-72	solute carrier family 6 member 9 L homeolog	Xenopus laevis	87-92
25025157-2	2014	Gephyrin is the major instructive molecule at inhibitory synapses, where it clusters glycine as well as major subsets of GABA type A receptors (GABAARs).	Glycine	85-92	gephyrin	Homo sapiens	0-8
18281307-8	2008	The MICs of cefotaxime were clearly lower for the Escherichia coli harbouring the Trp, Cys, Ser and Gly CTX-M-1 mutant enzymes than for CTX-M-1, and these enzymes showed a clearly reduced catalytic efficiency towards cefotaxime.	Glycine	100-103	CTX-M-1	Escherichia coli	104-111
18232718-4	2008	PEPs specifically cleaved ComCs after the Gly-Gly site in all the PEP-ComC combinations examined.	Glycine	42-45	progestagen associated endometrial protein	Homo sapiens	0-3
18232718-4	2008	PEPs specifically cleaved ComCs after the Gly-Gly site in all the PEP-ComC combinations examined.	Glycine	46-49	progestagen associated endometrial protein	Homo sapiens	0-3
16427628-2	2006	We showed that all RET-PTC-1 mutants in which the C in this motif (C376) was replaced with glycine, lysine, threonine or serine lost their activity in vitro.	Glycine	91-98	ret proto-oncogene	Homo sapiens	19-22
16417482-4	2006	GlyT1, in addition, is thought to regulate the concentration of glycine at excitatory synapses containing NMDARs (N-methyl-D-aspartate receptors), which require glycine as a co-agonist.	Glycine	64-71	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	0-5
18232718-7	2008	Together with the double glycine motif, these structural features of ComC would explain the strict substrate specificity of the PEP.	Glycine	25-32	progestagen associated endometrial protein	Homo sapiens	128-131
24375788-0	2014	In vivo analysis of Arg-Gly-Asp sequence/integrin alpha5beta1-mediated signal involvement in embryonic enchondral ossification by exo utero development system.	Glycine	24-27	5'-3' exoribonuclease 1	Mus musculus	130-133
18096599-1	2008	Early in development, GABA and glycine exert excitatory action that turns to inhibition due to modification of the chloride equilibrium potential (E(Cl)) controlled by the KCC2 and NKCC1 transporters.	Glycine	31-38	solute carrier family 12, member 5	Mus musculus	172-176
16417482-4	2006	GlyT1, in addition, is thought to regulate the concentration of glycine at excitatory synapses containing NMDARs (N-methyl-D-aspartate receptors), which require glycine as a co-agonist.	Glycine	161-168	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	0-5
16417482-6	2006	Our genetic results indicate that at glycinergic synapses, the glial transporter GlyT1 catalyses the removal of glycine from the synaptic cleft, whereas GlyT2 is required for the re-uptake of glycine into nerve terminals, thereby allowing for neurotransmitter reloading of synaptic vesicles.	Glycine	37-44	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	81-86
16417482-6	2006	Our genetic results indicate that at glycinergic synapses, the glial transporter GlyT1 catalyses the removal of glycine from the synaptic cleft, whereas GlyT2 is required for the re-uptake of glycine into nerve terminals, thereby allowing for neurotransmitter reloading of synaptic vesicles.	Glycine	112-119	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	81-86
18271919-2	2008	POEM has several characteristics of a matrix protein including an arg-gly-asp binding domain site that is recognized by integrins.	Glycine	70-73	nephronectin	Homo sapiens	0-4
24797328-6	2014	Hippocampal levels of glycine were decreased in sarcosine-treated animals, which was associated with a reduction of [(3)H] glycine uptake and a decrease in glycine transporter expression (GlyT-1 and GlyT-2).	Glycine	22-29	solute carrier family 6 member 5	Rattus norvegicus	199-205
17924589-7	2008	When combinations of the two polymorphisms were considered, patients who had T/T in the HTR2A gene and encoded Ser/Ser or Ser/Gly from DRD3 gene had a higher propensity to non-responsiveness compared to other subjects (OR = 3.57, 95%CI = 1.10-11.62, p = 0.039).	Glycine	126-129	dopamine receptor D3	Homo sapiens	135-139
17962328-1	2008	Heteromeric NMDARs are composed of coagonist glycine-binding NR1 subunits and glutamate-binding NR2 subunits.	Glycine	45-52	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	61-64
17962328-4	2008	This heterogeneity is specified by the particular NR2 subunit within the NMDAR complex since the glycine-binding NR1 subunit is common to all NMDARs investigated.	Glycine	97-104	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	113-116
16182535-6	2006	Mutation of residues 846 and 883 to alanine and glycine, respectively, conferred novel inhibitor sensitivity onto PTPH1.	Glycine	48-55	protein tyrosine phosphatase non-receptor type 3	Homo sapiens	114-119
24698160-1	2014	UNLABELLED: Serine hydroxymethyltransferase (SHMT) catalyzes the transfer of a hydroxymethyl group from l-serine to tetrahydrofolate to yield glycine and 5,10-methylenetetrahydrofolate.	Glycine	142-149	serine hydroxymethyltransferase 1	Homo sapiens	45-49
16728410-1	2006	The MGOUN3(MGO3)/BRUSHY1(BRU1)/TONSOKU(TSK) gene of Arabidopsis thaliana encodes a nuclear leucine-glycine-asparagine (LGN) domain protein that may be implicated in chromatin dynamics and genome maintenance.	Glycine	99-106	tetratricopeptide repeat (TPR)-containing protein	Arabidopsis thaliana	4-10
16728410-1	2006	The MGOUN3(MGO3)/BRUSHY1(BRU1)/TONSOKU(TSK) gene of Arabidopsis thaliana encodes a nuclear leucine-glycine-asparagine (LGN) domain protein that may be implicated in chromatin dynamics and genome maintenance.	Glycine	99-106	tetratricopeptide repeat (TPR)-containing protein	Arabidopsis thaliana	11-15
16728410-1	2006	The MGOUN3(MGO3)/BRUSHY1(BRU1)/TONSOKU(TSK) gene of Arabidopsis thaliana encodes a nuclear leucine-glycine-asparagine (LGN) domain protein that may be implicated in chromatin dynamics and genome maintenance.	Glycine	99-106	tetratricopeptide repeat (TPR)-containing protein	Arabidopsis thaliana	39-42
17962328-9	2008	We conclude that the variation in glycine potency is caused by interactions between the NR1 and NR2 ligand-binding domains that occur following agonist binding and which may be involved in the initial conformation changes that determine channel gating.	Glycine	34-41	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	88-91
17655979-3	2008	The hyperekplexia mutation increased the positive cooperativity of 0.3 mM propofol and glycine binding by about six times: the cooperativity factor beta was 0.26 for alpha1 GlyRs and 0.04 for alpha1(R271L) GlyRs.	Glycine	87-94	glycine receptor alpha 1	Homo sapiens	166-178
17655979-3	2008	The hyperekplexia mutation increased the positive cooperativity of 0.3 mM propofol and glycine binding by about six times: the cooperativity factor beta was 0.26 for alpha1 GlyRs and 0.04 for alpha1(R271L) GlyRs.	Glycine	87-94	adrenoceptor alpha 1D	Homo sapiens	166-171
24631830-5	2014	Adopting the reduced chemical diversity design and further restricting the interface diversity to tyrosines, serines, glycines, and arginines only, we have constructed a RNA-targeting Fab library.	Glycine	118-126	FA complementation group B	Homo sapiens	184-187
17944872-2	2007	The aim of this work was to characterize the release of the amino acid from spinal cord glycinergic nerve endings selectively pre-labeled through glycine transporters of the GLYT2 type.	Glycine	88-95	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	174-179
18029478-3	2007	Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of glycine and serine, another 1-carbon donor.	Glycine	72-79	serine hydroxymethyltransferase 1	Homo sapiens	0-31
16573089-1	2006	The single-crystalline CdS dendrites have been fabricated from the reaction of CdCl2 and thiourea at 180 degrees C, in which glycine was employed as a soft template.	Glycine	125-132	CDP-diacylglycerol synthase 1	Homo sapiens	23-26
16294047-4	2005	Here we show that a glycine-arginine rich (GAR) stretch of 53BP1 lying upstream of the Tudor motifs is methylated.	Glycine	20-27	tumor protein p53 binding protein 1	Homo sapiens	59-64
18029478-3	2007	Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of glycine and serine, another 1-carbon donor.	Glycine	72-79	serine hydroxymethyltransferase 1	Homo sapiens	33-37
18029478-8	2007	Serine synthesis by direct conversion from glycine via SHMT occurred at 193 +/- 28 micromol x kg(-1) x h(-1) (mean +/- SEM), which comprised 41% of the 463 +/- 55 micromol x kg(-1) x h(-1) total glycine flux.	Glycine	43-50	serine hydroxymethyltransferase 1	Homo sapiens	55-59
18029478-8	2007	Serine synthesis by direct conversion from glycine via SHMT occurred at 193 +/- 28 micromol x kg(-1) x h(-1) (mean +/- SEM), which comprised 41% of the 463 +/- 55 micromol x kg(-1) x h(-1) total glycine flux.	Glycine	195-202	serine hydroxymethyltransferase 1	Homo sapiens	55-59
18029478-11	2007	This study is the first to our knowledge to quantify human glycine cleavage and glycine-to-serine SHMT kinetics.	Glycine	80-87	serine hydroxymethyltransferase 1	Homo sapiens	98-102
24816100-2	2014	This activation is a three-step process in which ubiquitin is adenylated at its C-terminal glycine, followed by the covalent attachment of ubiquitin to a catalytic cysteine residue of Uba1 and the subsequent adenylation of a second ubiquitin.	Glycine	91-98	ubiquitin like modifier activating enzyme 1	Homo sapiens	184-188
17978471-6	2007	The highest dose of glycine inhibited the alpha-MSH-induced increment of tyrosinase protein levels in B16F0 melanoma cells.	Glycine	20-27	tyrosinase	Mus musculus	73-83
17978471-11	2007	These results suggest that glycine has an inhibitory effect on melanogenesis that is mediated by down-regulation of tyrosinase protein levels, leading to a hypopigmenting effect in C57BL/6J mice.	Glycine	27-34	tyrosinase	Mus musculus	116-126
16511201-1	2005	The product of the human leukocyte antigen (HLA) gene HLA-B*2704 differs from that of the prototypical subtype HLA-B*2705 by three amino acids at heavy-chain residues 77 (Ser instead of Asp), 152 (Glu instead of Val) and 211 (Gly instead of Ala).	Glycine	226-229	major histocompatibility complex, class I, B	Homo sapiens	54-59
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	195-198	peroxiredoxin 5	Homo sapiens	4-25
16211657-6	2005	EMC-Arg-Arg-Ser-Ser-Tyr-Tyr-Ser-Gly-DOXO showed no in vivo activity in the PSA-negative PC 3 model, but good activity in the CWR22 PSA-positive model that was comparable to Doxorubicin.	Glycine	32-35	kallikrein related peptidase 3	Homo sapiens	131-134
16115813-2	2005	In humans, low levels of functional serum MBL are caused by the dominant action of three single nucleotide substitutions in exon 1 that disrupt the glycine-rich backbone structure of the protein.	Glycine	148-155	mannose binding lectin 2	Homo sapiens	42-45
17726027-6	2007	Morphological FRET was utilized to demonstrate that secretin receptor oligomerization occurred at the cell surface and that this oligomerization was disrupted by mutating Gly(243) and Ile(247), key residues within the lipid-exposed face of TM IV.	Glycine	171-174	secretin receptor	Homo sapiens	52-69
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	195-198	peroxiredoxin 5	Homo sapiens	27-31
17627859-6	2007	The most abundant amino acids in the P60 that account for 68.3% of the total residues are glycine (32.1%), aspartic acid (17.4%), alanine (13.6%), and glutamic acid (5.2%).	Glycine	90-97	plasma protein 1	Mus musculus	37-40
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	207-210	peroxiredoxin 5	Homo sapiens	4-25
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	207-210	peroxiredoxin 5	Homo sapiens	27-31
24560924-4	2014	Structural analysis of oncogenic M918T and wild-type RET kinase domains reveal a cis-inhibitory mechanism involving tethering contacts between the glycine-rich loop, activation loop, and alphaC-helix.	Glycine	147-154	ret proto-oncogene	Homo sapiens	53-56
17646495-2	2007	METHODS: We tested this prediction by applying acetylcholine to a NR1/NR2A N-methyl-d-aspartate receptor, glycine to a wild-type alpha(1)beta(2) and anesthetic-resistant alpha(1)(S270I)beta(2) gamma-amino-butyric acid (GABA) type A receptor, and GABA to a homomeric alpha(1) wild type and anesthetic-resistant alpha(1) S267I glycine receptor.	Glycine	106-113	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	66-69
16147988-3	2005	The ssu71-1 and ssu71-2 alleles were cloned and found to encode single amino acid replacements of glycine-363, either glycine to aspartic acid (G363D) or glycine to arginine (G363R).	Glycine	98-105	transcription factor IIF subunit TFG1	Saccharomyces cerevisiae S288C	4-9
16147988-3	2005	The ssu71-1 and ssu71-2 alleles were cloned and found to encode single amino acid replacements of glycine-363, either glycine to aspartic acid (G363D) or glycine to arginine (G363R).	Glycine	98-105	transcription factor IIF subunit TFG1	Saccharomyces cerevisiae S288C	16-21
16147988-3	2005	The ssu71-1 and ssu71-2 alleles were cloned and found to encode single amino acid replacements of glycine-363, either glycine to aspartic acid (G363D) or glycine to arginine (G363R).	Glycine	118-125	transcription factor IIF subunit TFG1	Saccharomyces cerevisiae S288C	4-9
16147988-3	2005	The ssu71-1 and ssu71-2 alleles were cloned and found to encode single amino acid replacements of glycine-363, either glycine to aspartic acid (G363D) or glycine to arginine (G363R).	Glycine	118-125	transcription factor IIF subunit TFG1	Saccharomyces cerevisiae S288C	16-21
16147988-3	2005	The ssu71-1 and ssu71-2 alleles were cloned and found to encode single amino acid replacements of glycine-363, either glycine to aspartic acid (G363D) or glycine to arginine (G363R).	Glycine	118-125	transcription factor IIF subunit TFG1	Saccharomyces cerevisiae S288C	4-9
16147988-3	2005	The ssu71-1 and ssu71-2 alleles were cloned and found to encode single amino acid replacements of glycine-363, either glycine to aspartic acid (G363D) or glycine to arginine (G363R).	Glycine	118-125	transcription factor IIF subunit TFG1	Saccharomyces cerevisiae S288C	16-21
17554807-0	2007	Transport of a tripeptide, Gly-Pro-Hyp, across the porcine intestinal brush-border membrane.	Glycine	27-30	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	35-38
24096584-6	2014	Importantly, mutation(s) of the type like deletion of A nucleotide and missense mutation (Gly &gt; Val) exclusively showed low (+) or no expression for the CYP1A1 protein when studied in relation to each other.	Glycine	90-93	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	156-162
17554807-8	2007	These results indicate that Gly-Pro-Hyp can be partially hydrolyzed by the brush-border membrane-bound aminopeptidase N to remove Gly, and that the resulting Pro-Hyp is, in part, transported into the small intestinal epithelial cells via the H+-coupled PEPT1.	Glycine	28-31	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	36-39
17554807-8	2007	These results indicate that Gly-Pro-Hyp can be partially hydrolyzed by the brush-border membrane-bound aminopeptidase N to remove Gly, and that the resulting Pro-Hyp is, in part, transported into the small intestinal epithelial cells via the H+-coupled PEPT1.	Glycine	28-31	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	162-165
17554807-8	2007	These results indicate that Gly-Pro-Hyp can be partially hydrolyzed by the brush-border membrane-bound aminopeptidase N to remove Gly, and that the resulting Pro-Hyp is, in part, transported into the small intestinal epithelial cells via the H+-coupled PEPT1.	Glycine	130-133	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	36-39
17554807-8	2007	These results indicate that Gly-Pro-Hyp can be partially hydrolyzed by the brush-border membrane-bound aminopeptidase N to remove Gly, and that the resulting Pro-Hyp is, in part, transported into the small intestinal epithelial cells via the H+-coupled PEPT1.	Glycine	130-133	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	162-165
17582333-7	2007	Long-term potentiation (LTP) induced by brief glycine application resulted in synaptic insertion of GluR1-containing AMPA receptors along with Kv4.2 internalization.	Glycine	46-53	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	100-105
17342702-1	2007	The equilibrium molecular structures of the two lowest-energy conformers of glycine, Gly-Ip and Gly-IIn, have been characterized by high-level ab initio electronic structure computations, including all-electron cc-pVTZ CCSD(T) geometry optimizations and 6-31G* MP2 quartic force fields, the latter to account for anharmonic zero-point vibrational effects to isotopologic rotational constants.	Glycine	76-83	glyoxalase I	Homo sapiens	85-91
17427808-8	2007	Together, these data indicate that EACMCV AC4 is likely dually acylated at Gly-2 and Cys-3 and that these modifications are intrinsic signals for membrane targeting and pathogenesis.	Glycine	75-78	transcriptional regulator AC4	East African cassava mosaic Cameroon virus	42-45
17306467-5	2007	In addition, BDNF caused a significant increase in glycine- and GABA-evoked current densities that partly explains the increase in synaptic transmission.	Glycine	51-58	brain derived neurotrophic factor	Mus musculus	13-17
17407504-4	2007	The presence of the glycine allele at the S9G polymorphism of the DRD3 gene was associated with frequency/quantity measures of smoking [log-transformed time to first cigarette (P = 0.031) and heaviness of smoking index (P = 0.035)].	Glycine	20-27	dopamine receptor D3	Homo sapiens	66-70
17446496-5	2007	Site-directed mutageneses have revealed that these inhibitors possess some molecular determinants (Phe-213, Val-227, Tyr-228, Gly-833, and Asn-839) for interaction with NCX1.	Glycine	126-129	T cell leukemia, homeobox 2	Mus musculus	169-173
17142278-0	2007	Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin.	Glycine	24-31	myosin heavy chain 14	Homo sapiens	92-98
17361008-2	2007	NKH is caused by deficiency of the glycine cleavage multienzyme system with three specific components encoded by GLDC, AMT and GCSH.	Glycine	35-42	aminomethyltransferase	Homo sapiens	119-122
17320117-0	2007	Characterisation of the human NMDA receptor subunit NR3A glycine binding site.	Glycine	57-64	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	52-56
17320117-2	2007	Saturation radioligand binding of the NMDA receptor agonists [(3)H]-glycine and [(3)H]-glutamate showed that only glycine binds to human NR3A (hNR3A) with high affinity (K(d)=535nM (277-793nM)).	Glycine	114-121	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	137-141
17320117-2	2007	Saturation radioligand binding of the NMDA receptor agonists [(3)H]-glycine and [(3)H]-glutamate showed that only glycine binds to human NR3A (hNR3A) with high affinity (K(d)=535nM (277-793nM)).	Glycine	114-121	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	143-148
17320117-3	2007	Eight amino acids, which correspond to amino acids that are critical for ligand binding to other NMDA receptor subunits, situated within the S1S2 predicted ligand binding domain of hNR3A were mutated, which resulted in complete or near complete loss of [(3)H]-glycine binding to hNR3A.	Glycine	260-267	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	181-186
17320117-7	2007	Our data show that glycine is a ligand, and most probably the endogenous ligand, for native NR3A at a binding site with unique pharmacological characteristics.	Glycine	19-26	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	92-96
17493893-2	2007	We analyzed blood samples from an EDMD family, including a mother and two daughters, and found a novel mutation in codon 520 in exon 9 of the lamin A/C (LMNA) gene, resulting in a substitution of tryptophan (W) by glycine (G) in all three patients.	Glycine	214-221	lamin A/C	Homo sapiens	142-151
17493893-2	2007	We analyzed blood samples from an EDMD family, including a mother and two daughters, and found a novel mutation in codon 520 in exon 9 of the lamin A/C (LMNA) gene, resulting in a substitution of tryptophan (W) by glycine (G) in all three patients.	Glycine	214-221	lamin A/C	Homo sapiens	153-157
17098236-2	2007	The medaka ppTRH cDNA codes for 270 amino acid residues including eight TRH progenitor sequences (-Lys/Arg-Arg-Gln-His-Pro-Gly-Lys/Arg-Arg-).	Glycine	123-126	thyrotropin-releasing hormone	Oryzias latipes	11-16
17224050-7	2007	Site directed mutation also reveals that amino acid residues Gly 70 and Val 72 are important in the VP2-vimentin association.	Glycine	61-64	vimentin	Homo sapiens	104-112
17252560-4	2007	Cell wash with an acidic buffer (0.2M glycine-0.15M NaCl, pH 3.0) was thus employed in this study to remove cell-surface adsorbed CPP-(125)I-Fab conjugates.	Glycine	38-45	FA complementation group B	Homo sapiens	141-144
17229147-4	2007	NMR spectroscopy revealed that fowlicidin-3 comprises 27 amino-acid residues and adopts a predominantly alpha-helical structure extending from residue 9 to 25 with a slight kink induced by a glycine at position 17.	Glycine	191-198	cathelicidin-3	Gallus gallus	31-43
17146529-1	2006	The condensation process catalysed by 2-amino-3-oxobutyrate CoA ligase (KBL; also known as 2-amino-3-ketobutyrate ligase) involves the loss of the pro-R hydrogen atom of glycine and occurs with the inversion of stereochemistry; a similar scenario is envisaged for the condensation step of other alpha-oxoamine synthases.	Glycine	170-177	glycine C-acetyltransferase	Homo sapiens	72-75
17182766-1	2006	Classical NMDA receptors (NMDARs), activated by glycine and glutamate, are heteromultimers comprised of NR1 and NR2 subunits.	Glycine	48-55	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	104-107
17128981-9	2006	According to molecular modeling of pepsin B, Tyr13 OH narrows the substrate-binding space and a peptide with Gly at P2 might be preferentially accommodated because of its high flexibility.	Glycine	109-112	pepsinogen B1	Canis lupus familiaris	35-43
16980404-1	2006	Serine hydroxymethyl transferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	163-170	serine hydroxymethyltransferase 1	Homo sapiens	0-32
16980404-1	2006	Serine hydroxymethyl transferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	163-170	serine hydroxymethyltransferase 1	Homo sapiens	34-38
17010377-6	2006	Furthermore, the double Asp-Thr-Gly-Ala amino acid sequence motif at the active site of HIV protease is found with identical geometry in the Ddi1 structure.	Glycine	32-35	Ddi1p	Saccharomyces cerevisiae S288C	141-145
17083745-7	2006	We show that disruption of the N-terminal myristoylation signal by substituting the N-terminal glycine with alanine (Z-G2A mutant) resulted in a significant reduction of Z protein association with cellular membranes.	Glycine	95-102	transmembrane BAX inhibitor motif containing 4	Homo sapiens	170-179
17009119-8	2006	A 5 mM Gly-Gly perfusion completely inhibited the MPO activity and colonic wall damage induced by 10 muM fMLP.	Glycine	7-10	myeloperoxidase	Rattus norvegicus	50-53
17009119-8	2006	A 5 mM Gly-Gly perfusion completely inhibited the MPO activity and colonic wall damage induced by 10 muM fMLP.	Glycine	11-14	myeloperoxidase	Rattus norvegicus	50-53
17040296-6	2006	Further, the tumor cells had intense nuclear accumulation of beta-catenin and an activating mutation, (34)Gly(GGA) to Arg(AGA), in exon 3 of the beta-catenin gene, as previously reported in most SPT.	Glycine	106-109	catenin beta 1	Homo sapiens	145-157
16130093-7	2005	Here, for the first time, we report a genotype-phenotype correlation demonstrating that heterozygous glycine substitutions in the triple-helix domain of COL6A1 are dominant and responsible for a milder Ullrich scleroatonic muscular dystrophy phenotype, and that recessive mutations in COL6A1 correlate with more severe clinical and biochemical Ullrich scleroatonic muscular dystrophy phenotypes.	Glycine	101-108	collagen type VI alpha 1 chain	Homo sapiens	153-159
16130093-7	2005	Here, for the first time, we report a genotype-phenotype correlation demonstrating that heterozygous glycine substitutions in the triple-helix domain of COL6A1 are dominant and responsible for a milder Ullrich scleroatonic muscular dystrophy phenotype, and that recessive mutations in COL6A1 correlate with more severe clinical and biochemical Ullrich scleroatonic muscular dystrophy phenotypes.	Glycine	101-108	collagen type VI alpha 1 chain	Homo sapiens	285-291
16126914-1	2005	The proton-coupled amino acid transporter PAT1, cloned recently from brain and intestine, mediates the uphill transport of l- and d-proline, l-alanine, glycine, taurine, d-serine, GABA, and many other related compounds and drugs.	Glycine	152-159	solute carrier family 36 member 1	Homo sapiens	42-46
16126914-5	2005	When PAT1 was expressed in Xenopus laevis oocytes and analyzed by the two-electrode voltage clamp technique, glycine elicited high inward currents that were dependent on membrane potential but no currents were observed with l-tryptophan, tryptamine, 5-hydroxy-l-tryptophan, or serotonin.	Glycine	109-116	solute carrier family 36 member 1	Homo sapiens	5-9
15929988-6	2005	Processing by cathepsin K occurred sequentially by an initial excision of the loop peptide Gly(143)-Gly(160) followed by the removal of a Val(161)-Ala(162) dipeptide at the N terminus of the C-terminal 16-kDa TRAP subunit.	Glycine	91-94	cathepsin K	Rattus norvegicus	14-25
15929988-6	2005	Processing by cathepsin K occurred sequentially by an initial excision of the loop peptide Gly(143)-Gly(160) followed by the removal of a Val(161)-Ala(162) dipeptide at the N terminus of the C-terminal 16-kDa TRAP subunit.	Glycine	100-103	cathepsin K	Rattus norvegicus	14-25
15929988-7	2005	Cathepsin L initially released a shorter Gln(151)-Gly(160) peptide and completed processing at Ser(145) or Gly(143) at the C terminus of the N-terminal 23-kDa TRAP subunit and at Arg(163) at the N terminus of the C-terminal 16-kDa TRAP subunit.	Glycine	50-53	cathepsin L	Rattus norvegicus	0-11
15929988-7	2005	Cathepsin L initially released a shorter Gln(151)-Gly(160) peptide and completed processing at Ser(145) or Gly(143) at the C terminus of the N-terminal 23-kDa TRAP subunit and at Arg(163) at the N terminus of the C-terminal 16-kDa TRAP subunit.	Glycine	107-110	cathepsin L	Rattus norvegicus	0-11
16012719-3	2005	The effect of gastrin or glycine-extended gastrin on the growth of gastric cancer cell lines was determined by MTT assay.	Glycine	25-32	gastrin	Homo sapiens	42-49
16012719-6	2005	Growth of gastric cancer cell lines containing the gastrin/CCKB receptor was significantly enhanced by gastrin and glycine-extended gastrin.	Glycine	115-122	gastrin	Homo sapiens	51-58
15741239-6	2005	L-Glycine or L-alanine mimicked the effect of glucose on basal leptin secretion but completely prevented stimulation by insulin.	Glycine	0-9	leptin	Homo sapiens	63-69
16014854-8	2005	However, the presence of the triple mutant dhfr (Ile-51/Arg-59/Asn-108) with the dhps Gly-437 genotype in all recurring infections, suggests the importance of codon 59 and 437 alleles in susceptibility to TRM/SMX.	Glycine	86-89	dihydrofolate reductase	Homo sapiens	43-47
15672418-6	2005	Here, we show that the intracellular accumulation of glycine in embryos is a direct function of the rate of glycine uptake via GLYT1.	Glycine	53-60	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	127-132
15672418-6	2005	Here, we show that the intracellular accumulation of glycine in embryos is a direct function of the rate of glycine uptake via GLYT1.	Glycine	108-115	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	127-132
15948949-5	2005	Addition of a Bas1p-LexA fusion protein to a strain with a LexAop-LacZ fusion showed a strong glycine effect both in a BAS2 and a bas2 background.	Glycine	94-101	Pho2p	Saccharomyces cerevisiae S288C	119-123
15948949-5	2005	Addition of a Bas1p-LexA fusion protein to a strain with a LexAop-LacZ fusion showed a strong glycine effect both in a BAS2 and a bas2 background.	Glycine	94-101	Pho2p	Saccharomyces cerevisiae S288C	130-134
15948949-6	2005	A Bas1p-VP16 fusion protein activated expression in a bas1bas2 strain but no glycine effect was observed while a Bas1p-Bas2p fusion protein activated expression to a lesser extent with a slight stimulation by glycine.	Glycine	209-216	Pho2p	Saccharomyces cerevisiae S288C	119-124
15944280-7	2005	With an accompanying increase in glycine, a shift in hydrophobicity was observed in the CDR-H3 loop from near neutral in fraction C (-0.08 +/- 0.03) to mild hydrophilic in fraction F (-0.17 +/- 0.02).	Glycine	33-40	cerebellar degeneration-related 3	Mus musculus	88-94
15998189-6	2005	These results suggest that the DRD3 variant containing glycine is associated with more efficient striatal habit learning in healthy controls and patients with schizophrenia.	Glycine	55-62	dopamine receptor D3	Homo sapiens	31-35
15929701-3	2005	Amino acid substitution at 264 from arginine (R) to glycine (G), lysine (K), or threonine (T) results in a low affinity peptide that binds to HLA-B27 inefficiently and is poorly recognized by T cells that respond to the wild-type peptide.	Glycine	52-59	major histocompatibility complex, class I, B	Homo sapiens	142-149
15853906-5	2005	Likewise, HLA-B*1587 is identical to HLA-B*15010101 except at codons 80-83 (Asn-Leu-Arg-Gly--&gt;Ile-Ala-Leu-Arg) which has been replaced by HLA-Bw4 motif.	Glycine	88-91	major histocompatibility complex, class I, B	Homo sapiens	10-15
15853906-5	2005	Likewise, HLA-B*1587 is identical to HLA-B*15010101 except at codons 80-83 (Asn-Leu-Arg-Gly--&gt;Ile-Ala-Leu-Arg) which has been replaced by HLA-Bw4 motif.	Glycine	88-91	major histocompatibility complex, class I, B	Homo sapiens	37-42
15811564-1	2005	A commonly occurring nucleotide polymorphism of the insulin-receptor substrate 2 (IRS-2) gene at amino acid 1057 from Glycine to Asparaginic acid (G1057D) was recently shown to be a determinant of insulin sensitivity in both glucose-tolerant individuals and those with type 2 diabetes.	Glycine	118-125	insulin receptor substrate 2	Homo sapiens	52-80
15811564-1	2005	A commonly occurring nucleotide polymorphism of the insulin-receptor substrate 2 (IRS-2) gene at amino acid 1057 from Glycine to Asparaginic acid (G1057D) was recently shown to be a determinant of insulin sensitivity in both glucose-tolerant individuals and those with type 2 diabetes.	Glycine	118-125	insulin receptor substrate 2	Homo sapiens	82-87
15660380-2	2005	Disease-causing mutations both in Nramp1 and Nramp2 occurring at the conserved two adjacent glycine residues located within the fourth transmembrane domain (TM4) suggest that TM4 may serve an important biological function.	Glycine	92-99	tropomyosin 4	Rattus norvegicus	157-160
15660380-2	2005	Disease-causing mutations both in Nramp1 and Nramp2 occurring at the conserved two adjacent glycine residues located within the fourth transmembrane domain (TM4) suggest that TM4 may serve an important biological function.	Glycine	92-99	tropomyosin 4	Rattus norvegicus	175-178
15690204-2	2005	Conserved glycines, Gly139 and Gly143, in the distal helix of human heme oxygenase-1 (HO-1) provide the flexibility required for the opening and closing of the heme active site for substrate binding and product dissociation during HO-1 catalysis.	Glycine	10-18	heme oxygenase 1	Homo sapiens	68-84
15690204-2	2005	Conserved glycines, Gly139 and Gly143, in the distal helix of human heme oxygenase-1 (HO-1) provide the flexibility required for the opening and closing of the heme active site for substrate binding and product dissociation during HO-1 catalysis.	Glycine	10-18	heme oxygenase 1	Homo sapiens	86-90
15690204-2	2005	Conserved glycines, Gly139 and Gly143, in the distal helix of human heme oxygenase-1 (HO-1) provide the flexibility required for the opening and closing of the heme active site for substrate binding and product dissociation during HO-1 catalysis.	Glycine	10-18	heme oxygenase 1	Homo sapiens	231-235
15539429-3	2005	Palmitoylation of the LHR was determined by incorporation of [3H]palmitic acid into wild-type (WT) or mutant receptor in which the potential palmitoylation sites, C643 and C644, were mutated to glycine residues.	Glycine	194-201	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	22-25
15697216-6	2005	Selective mutation of these residues on p51 to a glycine dramatically alters the stability of the RT-heterodimer suggesting that the fingers subdomain of p51 is also involved in stabilization of reverse transcriptase.	Glycine	49-56	tumor protein p63	Homo sapiens	40-43
15697216-6	2005	Selective mutation of these residues on p51 to a glycine dramatically alters the stability of the RT-heterodimer suggesting that the fingers subdomain of p51 is also involved in stabilization of reverse transcriptase.	Glycine	49-56	tumor protein p63	Homo sapiens	154-157
15671159-5	2005	Uniquely, all known mammalian orthologs of AQP6 have an asparagine residue (Asn-60) at the position corresponding to Gly-57.	Glycine	117-120	aquaporin 6	Homo sapiens	43-47
15671159-7	2005	Replacement of the glycine at this site in AQP0, AQP1, and AQP2 blocked expression of the mutants at the oocyte plasma membrane.	Glycine	19-26	aquaporin 2	Homo sapiens	59-63
15629462-4	2005	We transfected GlyRalpha1 or GlyRalpha1del into HEK293 cells, and then examined the glycine-activated currents using a whole-cell patch-clamp recording technique.	Glycine	84-91	glycine receptor alpha 1	Homo sapiens	15-25
15629462-6	2005	Moreover, dose-response curves indicated that the EC50 values for glycine differed significantly between the two GlyRalpha1 derivatives, although their Hill coefficients were similar.	Glycine	66-73	glycine receptor alpha 1	Homo sapiens	113-123
16935423-3	2006	In this study, we found that recombinant DJ-1 expressed in and purified from E. coli was specifically cleaved between glycine and proline at amino acid numbers 157 and 158, respectively, by treatment of DJ-1 with H2O2.	Glycine	118-125	Parkinsonism associated deglycase	Homo sapiens	41-45
16935423-3	2006	In this study, we found that recombinant DJ-1 expressed in and purified from E. coli was specifically cleaved between glycine and proline at amino acid numbers 157 and 158, respectively, by treatment of DJ-1 with H2O2.	Glycine	118-125	Parkinsonism associated deglycase	Homo sapiens	203-207
16998069-8	2006	Mutation of the conserved PDV1 C-terminal Gly residue did not block PDV1 insertion into the outer envelope membrane but did abolish its localization to the division site.	Glycine	42-45	plastid division1	Arabidopsis thaliana	26-30
16930618-10	2006	Studies of multiple substitutions at G20 and neighboring positions highlight the essential contributions of a glycine-specific tight turn and adjoining inter-subunit side-chain hydrogen bonds to the stability and architectural specificity of the intertwined dimer.	Glycine	110-117	chromosome 3 open reading frame 18	Homo sapiens	37-40
24411479-6	2014	The C-terminal Gly and a l-amino acid analogue at the Cys binding site were necessary for inhibition, suggesting that human GGT was highly selective for glutathione (gamma-Glu-l-Cys-Gly), whereas E. coli GGT are not selective for glutathione, but still retained the dipeptide (l-AA-Gly) binding site.	Glycine	15-18	gamma-glutamyltransferase 2, pseudogene	Homo sapiens	124-127
16923166-1	2006	The vesicular acetylcholine transporter (VAChT) contains six conserved sequence motifs that are rich in proline and glycine.	Glycine	116-123	solute carrier family 18 member A3	Homo sapiens	41-46
16870468-4	2006	Patch-clamp recording from hippocampal cultures of the NR2B KI mice demonstrated that their NMDA receptors have reduced sensitivity to both ifenprodil and CP-101,606, as predicted, but also have a lower affinity for glycine.	Glycine	216-223	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	55-59
15500450-0	2005	Compound heterozygosity for mutations Asp611--&gt;Tyr in KCNQ1 and Asp609--&gt;Gly in KCNH2 associated with severe long QT syndrome.	Glycine	79-82	potassium voltage-gated channel subfamily H member 2	Homo sapiens	86-91
15500450-2	2005	We have identified two heterozygous missense mutations in the KCNQ1 and KCNH2 (also known as HERG) genes [Asp611--&gt;Tyr (D611Y) in KCNQ1 and Asp609--&gt;Gly (D609G) in KCNH2] in a 2-year-old boy with LQTS.	Glycine	155-158	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	62-67
15500450-2	2005	We have identified two heterozygous missense mutations in the KCNQ1 and KCNH2 (also known as HERG) genes [Asp611--&gt;Tyr (D611Y) in KCNQ1 and Asp609--&gt;Gly (D609G) in KCNH2] in a 2-year-old boy with LQTS.	Glycine	155-158	potassium voltage-gated channel subfamily H member 2	Homo sapiens	72-77
24446171-4	2014	Mice homozygous for the null mutation in Dtnbp1 exhibited significantly reduced NMDAR-dependent synaptic potentiation compared to wild type mice, an effect that could be rescued by bath application of the NMDA receptor coagonist glycine (10 muM).	Glycine	229-236	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	80-85
15500450-2	2005	We have identified two heterozygous missense mutations in the KCNQ1 and KCNH2 (also known as HERG) genes [Asp611--&gt;Tyr (D611Y) in KCNQ1 and Asp609--&gt;Gly (D609G) in KCNH2] in a 2-year-old boy with LQTS.	Glycine	155-158	potassium voltage-gated channel subfamily H member 2	Homo sapiens	93-97
15456797-12	2005	Although gramicidin perforated-patch recordings revealed that GABA or glycine depolarized P5-P7 cells but hyperpolarized P14-P15 cells, the young depolarizing inputs were not suprathreshold.	Glycine	70-77	cyclin-dependent kinase inhibitor 2B	Rattus norvegicus	125-128
16938651-8	2006	The integrinalpha3beta(1) antagonists, anti-integrinbeta(1) monoclonal antibody and Gly-Arg-Gly-Asp (GRGD), decreased the expression of alpha-SMA protein and the percentage of alpha-SMA positive cells stimulated by TGF-beta(1) (both P &lt; 0.01).	Glycine	84-87	actin gamma 2, smooth muscle	Rattus norvegicus	136-145
24471655-0	2014	A new delta chain variant, Hb A2-Tunis [delta46(CD5)Gly   Glu; HBD: c.140G&gt;A], observed in a Tunisian family in association with a compound heterozygosity for Hb C [beta6(A3)Glu   Lys; HBB: c.19G&gt;A] beta(0)-thalassemia [IVS-I-1 (beta143, G&gt;A); HBB: c.92+1G&gt;A].	Glycine	52-55	CD5 molecule	Homo sapiens	48-51
16938651-8	2006	The integrinalpha3beta(1) antagonists, anti-integrinbeta(1) monoclonal antibody and Gly-Arg-Gly-Asp (GRGD), decreased the expression of alpha-SMA protein and the percentage of alpha-SMA positive cells stimulated by TGF-beta(1) (both P &lt; 0.01).	Glycine	84-87	actin gamma 2, smooth muscle	Rattus norvegicus	176-185
16938651-8	2006	The integrinalpha3beta(1) antagonists, anti-integrinbeta(1) monoclonal antibody and Gly-Arg-Gly-Asp (GRGD), decreased the expression of alpha-SMA protein and the percentage of alpha-SMA positive cells stimulated by TGF-beta(1) (both P &lt; 0.01).	Glycine	92-95	actin gamma 2, smooth muscle	Rattus norvegicus	136-145
16938651-8	2006	The integrinalpha3beta(1) antagonists, anti-integrinbeta(1) monoclonal antibody and Gly-Arg-Gly-Asp (GRGD), decreased the expression of alpha-SMA protein and the percentage of alpha-SMA positive cells stimulated by TGF-beta(1) (both P &lt; 0.01).	Glycine	92-95	actin gamma 2, smooth muscle	Rattus norvegicus	176-185
16953181-4	2006	Via the exchange of the third extracellular loop of the mCAT1 cDNA encoding receptor from the permissive mouse and the corresponding portion of cDNA encoding for the nonpermissive M. dunni receptor, we have identified the most critical amino acid residue, which is a glycine located at position 236 within the third extracellular loop of dCAT1.	Glycine	267-274	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	56-61
15684035-4	2005	Using recombinant proteins, we found uPAR directly binds alpha5beta1 and rather than blocking, renders fibronectin (Fn) binding by alpha5beta1 Arg-Gly-Asp (RGD) resistant.	Glycine	147-150	plasminogen activator, urokinase receptor	Homo sapiens	37-41
24471655-1	2014	We describe a new delta-globin variant, Hb A2-Tunis [delta46(CD5)Gly   Glu; HBD: c.140G&gt;A].	Glycine	65-68	CD5 molecule	Homo sapiens	61-64
24232602-8	2014	In A1-A5 and A8, position 514 amino acid (514 aa) of MX2 was glycine (Gly), which did not inhibit VSV multiplication, whereas in A6 and A7, 514 aa was arginine (Arg), which exhibited the antiviral ability against VSV.	Glycine	61-68	interferon-induced GTP-binding protein Mx2	Sus scrofa	53-56
16839110-0	2005	Interaction of Co+ and Co2+ with glycine.	Glycine	33-40	complement C2	Homo sapiens	23-26
16845394-5	2006	Similarly, an asparagine-to-glycine substitution in the lectin-EGF-like domain interface of L-selectin enhanced rolling adhesion under shear flow.	Glycine	28-35	selectin L	Homo sapiens	92-102
16909847-0	2006	[Molecular dynamics modeling of the substitution of serine for the conservative glycine in the G loop in the yeast cdc28-srm mutant using the crystalline lattice of human kinase CDK2].	Glycine	80-87	cyclin-dependent serine/threonine-protein kinase CDC28	Saccharomyces cerevisiae S288C	115-120
24232602-8	2014	In A1-A5 and A8, position 514 amino acid (514 aa) of MX2 was glycine (Gly), which did not inhibit VSV multiplication, whereas in A6 and A7, 514 aa was arginine (Arg), which exhibited the antiviral ability against VSV.	Glycine	70-73	interferon-induced GTP-binding protein Mx2	Sus scrofa	53-56
24975223-0	2014	Cloning of a cDNA encoding the Gly m Bd 28K precursor and its vacuole transport in tobacco BY2 suspension-cultured cells.	Glycine	31-34	F-box protein PP2-B11-like	Nicotiana tabacum	91-94
16467955-1	2006	Two polymorphic trinucleotide repeats of human androgen receptor gene (hAR), CAG and GGN which encode glutamine and glycine, have been shown to be associated with human diseases.	Glycine	116-123	lymphatic vessel endothelial hyaluronan receptor 1	Homo sapiens	71-74
15517394-7	2005	Our results establish that treatment of cultured human dermal fibroblasts with recombinant fibrillin-1 fragments containing the arginine-glycine-aspartic acid (RGD) integrin-binding motif of fibrillin-1 induces up-regulation of MMP-1 and MMP-3.	Glycine	137-144	fibrillin 1	Homo sapiens	91-102
15517394-7	2005	Our results establish that treatment of cultured human dermal fibroblasts with recombinant fibrillin-1 fragments containing the arginine-glycine-aspartic acid (RGD) integrin-binding motif of fibrillin-1 induces up-regulation of MMP-1 and MMP-3.	Glycine	137-144	fibrillin 1	Homo sapiens	191-202
26819895-2	2014	Backbone cleavages at the N-Calpha bonds of Xxx-Asp, Xxx-Asn, Xxx-Cys, and Gly-Xxx residues gave discontinuous intense peaks of c-ions, independent of positive and negative ion mode.	Glycine	75-78	CEA cell adhesion molecule 6	Homo sapiens	26-34
15738658-11	2005	Interestingly, real-time RT-PCR analysis showed that hFOB cultured on hydrophobic substrata, which have downregulated alphav and beta3 integrin subunits, displayed greater steady state mRNA levels of osteopontin, an extracellular matrix (ECM) protein containing the Arg-Gly-Asp (RGD) integrin recognition sequence, than did cells cultured on hydrophilic substrata.	Glycine	270-273	secreted phosphoprotein 1	Homo sapiens	200-211
15541350-9	2004	Substitution of Trp32 in the CBD by Gly, a mutation found in a patient, caused only a 30% decrease in laforin activity but abolished binding to and inhibition by glycogen, indicating that impaired glycogen binding is sufficient to cause Lafora disease.	Glycine	36-39	EPM2A glucan phosphatase, laforin	Homo sapiens	102-109
16762425-2	2006	This review focuses on the molecular function of two major classes of neurotransmitter transporter that are present in the cell membrane of neurons and/or glial cells: the solute carrier (SLC)1 transporter family, which includes the transporters that mediate the Na(+)-dependent uptake of glutamate, and the SLC6 transporter family, which includes the transporters that mediate the Na(+)-dependent uptake of dopamine, 5-HT, norepinephrine, glycine and GABA.	Glycine	440-447	melanin concentrating hormone receptor 1	Homo sapiens	172-193
24206001-5	2013	The extent of dimer formation decreased significantly for the folding of C-terminal cyt c mutants with reduced hydrophobicity achieved by replacement of hydrophobic residues with Gly in the C-terminal region, whereas a large amount of heterodimers was generated for the folding of a mixture of N- and C-terminal mutants.	Glycine	179-182	cytochrome c, somatic	Equus caballus	84-89
16158286-2	2006	Using these vectors, the AGX1 gene encoding alanine:glyoxylate aminotransferase (AGT) from S. cerevisiae, which converts glyoxylate into glycine but is not present in Ashbya gossypii, was expressed in A. gossypii.	Glycine	137-144	alanine--glyoxylate transaminase	Saccharomyces cerevisiae S288C	25-29
15590926-6	2004	In wild-type mice, Ser900 of NR2A, previously implicated in CaN-mediated glycine-independent desensitization, becomes chronically dephosphorylated by postnatal day 11 as NMDAR current decay times become faster.	Glycine	73-80	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	Mus musculus	29-33
24021960-7	2013	An interaction between the Val/Val genotype of the BDNF Val66Met and Gly/Gly polymorphism of the DRD3 Ser9Gly was found in BPII(+AD), but not in BP-II not comorbid with AD (BPI(-AD)) compared with healthy Controls.	Glycine	69-72	dopamine receptor D3	Homo sapiens	97-101
15555918-6	2004	Synaptic GlyRs were apposed to glycinergic boutons characterized by the expression of the vesicular and the plasma membrane transporters of glycine (VIAAT and GlyT2, respectively).	Glycine	31-38	solute carrier family 32 member 1	Homo sapiens	149-154
15555918-8	2004	Finally, GlyR clusters could be detected at synaptic sites with the GABAA receptor gamma2 subunit and gephyrin, suggesting that mixed GABA/glycine synapses might exist in the hippocampus.	Glycine	139-146	gephyrin	Homo sapiens	68-110
16817888-3	2006	Here we report that fowlicidin-1 mainly adopts an alpha-helical conformation with a slight kink induced by glycine close to the center, in addition to a short flexible unstructured region near the N terminus.	Glycine	107-114	cathelicidin-1	Gallus gallus	20-32
16720724-2	2006	FKBP12 binds to the glycine- and serine-rich motif (GS motif) of the TGF-beta type I receptor, and functions as a secure switch to prevent the leaky signal.	Glycine	20-27	transforming growth factor beta receptor 1	Homo sapiens	69-93
16701208-6	2006	Since GABA and glycine compete for vesicular uptake, these data point to a close association of Viaat with GABA-synthesizing enzymes as a key factor in specifying GABAergic neuronal phenotypes.	Glycine	15-22	solute carrier family 32 member 1	Homo sapiens	96-101
15474473-2	2004	The substitution of Val-45 of CYP2D1 by glycine decreased the microsomal content, whereas the substitution of Gly-45 of CYP2D2 by valine increased.	Glycine	110-113	cytochrome P450, family 2, subfamily d, polypeptide 2	Rattus norvegicus	120-126
15474473-5	2004	The substitution of Leu-43 and Gly-45 of CYP2D2 by valine and tryptophan, respectively, markedly decreased the P420 peak in parallel with an increase in P450 content.	Glycine	31-34	cytochrome P450, family 2, subfamily d, polypeptide 2	Rattus norvegicus	41-47
24021960-7	2013	An interaction between the Val/Val genotype of the BDNF Val66Met and Gly/Gly polymorphism of the DRD3 Ser9Gly was found in BPII(+AD), but not in BP-II not comorbid with AD (BPI(-AD)) compared with healthy Controls.	Glycine	69-72	bactericidal permeability increasing protein	Homo sapiens	173-181
24021960-7	2013	An interaction between the Val/Val genotype of the BDNF Val66Met and Gly/Gly polymorphism of the DRD3 Ser9Gly was found in BPII(+AD), but not in BP-II not comorbid with AD (BPI(-AD)) compared with healthy Controls.	Glycine	73-76	dopamine receptor D3	Homo sapiens	97-101
24021960-7	2013	An interaction between the Val/Val genotype of the BDNF Val66Met and Gly/Gly polymorphism of the DRD3 Ser9Gly was found in BPII(+AD), but not in BP-II not comorbid with AD (BPI(-AD)) compared with healthy Controls.	Glycine	73-76	bactericidal permeability increasing protein	Homo sapiens	173-181
16520377-8	2006	Capitalizing on its unique preference for proline and glycine at the P2 and P3 positions, respectively, selective substrates and a substrate-based inhibitor were developed for cathepsin K.	Glycine	54-61	cathepsin K	Homo sapiens	176-187
24021960-10	2013	Because the Val/Val genotype of the BDNF Val66Met polymorphism, rather than the other two polymorphisms, has been associated with anxiety, it seems to affect BP-I comorbid with AD without the involvement of the DRD3 Seg9Gly polymorphism, but may modify the involvement of DRD3 Gly/Gly in BP-II comorbid with AD.	Glycine	220-223	bactericidal permeability increasing protein	Homo sapiens	158-162
24021960-10	2013	Because the Val/Val genotype of the BDNF Val66Met polymorphism, rather than the other two polymorphisms, has been associated with anxiety, it seems to affect BP-I comorbid with AD without the involvement of the DRD3 Seg9Gly polymorphism, but may modify the involvement of DRD3 Gly/Gly in BP-II comorbid with AD.	Glycine	277-280	bactericidal permeability increasing protein	Homo sapiens	158-162
24100027-5	2013	Trp-281 of ArsB corresponded to Gly-284 of ArsC in the amino acid sequence alignment.	Glycine	32-35	arylsulfatase B	Homo sapiens	11-15
16518797-2	2006	Jupiter is a soluble unfolded molecule with the high net positive charge, rich in Glycine.	Glycine	82-89	jupiter	Drosophila melanogaster	0-7
15240345-10	2004	Mitochondria, which produce glyoxylate from hydroxyproline metabolism, contained both alanine:glyoxylate aminotransferase (AGT)2 and glyoxylate reductase activities, which can convert glyoxylate to glycine and glycolate, respectively.	Glycine	198-205	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	86-121
15485496-4	2004	Paired pulse experiments and direct injection of PKA inhibitor fragment 6-22 amide (PKI(6-22)) into the recording neuron revealed that these effects on eIPSC amplitude occurred presynaptically, indicating that evoked glycine release is regulated by presynaptic cAMP via changes in PKA activity.	Glycine	217-224	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	49-52
15485496-4	2004	Paired pulse experiments and direct injection of PKA inhibitor fragment 6-22 amide (PKI(6-22)) into the recording neuron revealed that these effects on eIPSC amplitude occurred presynaptically, indicating that evoked glycine release is regulated by presynaptic cAMP via changes in PKA activity.	Glycine	217-224	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	281-284
24100027-5	2013	Trp-281 of ArsB corresponded to Gly-284 of ArsC in the amino acid sequence alignment.	Glycine	32-35	steroid sulfatase	Homo sapiens	43-47
24100027-8	2013	These results indicate that this amino acid residue (Trp-281 of ArsB or Gly-284 of ArsC) should occupy a critical position for the cyclization specificity of each enzyme.	Glycine	72-75	arylsulfatase B	Homo sapiens	64-68
16497796-2	2006	The decapeptide, LHRH, is processed by a zinc metalloendopeptidase EC 3.4.24.15 (EP24.15) that cleaves the hormone at the Tyr(5)-Gly(6) bond.	Glycine	129-132	gonadotropin releasing hormone 1	Rattus norvegicus	17-21
24100027-8	2013	These results indicate that this amino acid residue (Trp-281 of ArsB or Gly-284 of ArsC) should occupy a critical position for the cyclization specificity of each enzyme.	Glycine	72-75	steroid sulfatase	Homo sapiens	83-87
23988852-4	2013	In accordance with this change, PEPT2 activity estimated as cefadroxil-sensitive [(3)H]Gly-Sar uptake also decreased along with transdifferentiation.	Glycine	87-90	solute carrier family 15 member 2	Rattus norvegicus	32-37
16585174-2	2006	Human umbilical vascular endothelial cells (HUVEC) were assessed for tubule formation in the presence of amidated gastrin-17 (G17) and glycine-extended gastrin-17 (GlyG17) peptides.	Glycine	135-142	gastrin	Homo sapiens	152-159
15450847-2	2004	To assess its role in catalysis, it was mutated to Gly, the residue present in mammalian DAAO, an enzyme with a 35-fold lower turnover number with D-alanine.	Glycine	51-54	D-amino acid oxidase	Homo sapiens	89-93
15486200-7	2004	Using Chinese hamster ovary cells transfected with either wild-type or mutant integrin alpha(4), a critical binding site for these peptides was localized to the glycine residue at position 190 of integrin alpha(4).	Glycine	161-168	integrin alpha-4	Cricetulus griseus	78-95
15486200-7	2004	Using Chinese hamster ovary cells transfected with either wild-type or mutant integrin alpha(4), a critical binding site for these peptides was localized to the glycine residue at position 190 of integrin alpha(4).	Glycine	161-168	integrin alpha-4	Cricetulus griseus	196-213
24020881-0	2013	Effect of hydrogen bond formation on the NMR properties of glycine-HCN complexes.	Glycine	59-66	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	67-70
16381810-4	2006	Using whole cell current-clamp recordings, we show that activation of strychnine-sensitive GlyRs through exogenous glycine application causes a significant decrease in input resistance and prevents somatically generated action potentials in both CA1 pyramidal cells and interneurons.	Glycine	115-122	carbonic anhydrase 1	Rattus norvegicus	246-249
24020881-1	2013	The influence of the hydrogen bond formation on the nuclear magnetic resonance parameters has been investigated for the binary (1:1) and ternary (1:2) glycine-HCN complexes in the gas phase using high-level density functional theory with the B3LYP/6-31++G(2d,2p)//B3LYP/6-31++G(d,p) model of quantum chemistry.	Glycine	151-158	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	159-162
15210705-4	2004	In Caenorhabditis elegans, mutation of a glycine to an aspartic acid within a conserved GXXXG motif in the fourth transmembrane domain of APH-1 causes a loss of function phenotype.	Glycine	41-48	Gamma-secretase subunit aph-1	Caenorhabditis elegans	138-143
23733502-0	2013	Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor.	Glycine	74-81	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	98-127
16548523-2	2006	We previously showed that hypochlorous acid (HOCl), a specific product of myeloperoxidase, inactivates matrilysin by modifying adjacent tryptophan and glycine (WG) residues in the catalytic domain.	Glycine	151-158	matrix metallopeptidase 7	Homo sapiens	103-113
23733502-5	2013	The enhancement of LTP by sunifiram treatment was inhibited by 7-chloro-kynurenic acid (7-ClKN), an antagonist for glycine-binding site of NMDAR, but not by ifenprodil, an inhibitor for polyamine site of NMDAR.	Glycine	115-122	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	139-144
16169610-0	2006	Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways.	Glycine	0-7	gastrin	Homo sapiens	17-24
16169610-1	2006	Glycine-extended gastrin (G-Gly) is an end product of processing of the progastrin precursor peptide that has a different spectrum of activity to amidated gastrin.	Glycine	0-7	gastrin	Homo sapiens	17-24
16379012-3	2006	We investigated the effect of an alanine to glycine substitution found in the NEMO polypeptide of an EDA-ID patient.	Glycine	44-51	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma	Homo sapiens	78-82
16442704-0	2006	Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.	Glycine	0-7	gastrin	Homo sapiens	17-24
16442704-1	2006	Glycine-extended gastrin (G-Gly) is produced by colon cancers and has growth promoting and anti-apoptotic effects in the colonic epithelium.	Glycine	0-7	gastrin	Homo sapiens	17-24
15334382-8	2004	Our findings suggest that the beta(2)-AR Arg(16)-Gly genotype influences T-C and LDL-C levels in an age-specific manner, that it may interact with beta(3)-AR Trp(64)-Arg genotypes to influence longitudinal T-C and LDL-C profiles, and that the effect of combined beta(2)/beta(3)-AR genotypes on T-C and LDL-C profiles may differ among race/sex groups.	Glycine	49-52	adrenoceptor beta 3	Homo sapiens	270-280
15249229-1	2004	Although human group VIB calcium-independent phospholipase A(2) (iPLA(2)gamma) contains the lipase-consensus sequence Gly-Xaa-Ser-Xaa-Gly in the C-terminal half, its overall sequence exhibits a week similarity to those of other PLA(2)s, and thus no information on the catalytic site has been available.	Glycine	118-121	patatin like phospholipase domain containing 8	Homo sapiens	65-77
15249229-1	2004	Although human group VIB calcium-independent phospholipase A(2) (iPLA(2)gamma) contains the lipase-consensus sequence Gly-Xaa-Ser-Xaa-Gly in the C-terminal half, its overall sequence exhibits a week similarity to those of other PLA(2)s, and thus no information on the catalytic site has been available.	Glycine	134-137	patatin like phospholipase domain containing 8	Homo sapiens	65-77
16332990-4	2006	The potentiation of I(Gly) by THC and AEA is concentration-dependent, with respective EC50 values of 86 +/- 9 and 319 +/- 31 nM for alpha1 homomeric receptors, 73 +/- 8 and 318 +/- 24 nM for alpha1beta1 heteromeric receptors, and 115 +/- 13 and 230 +/- 29 nM for native GlyRs in VTA neurons.	Glycine	22-25	adrenoceptor alpha 1D	Homo sapiens	132-138
23393157-1	2013	The GPHN gene codes for gephyrin, a key scaffolding protein in the neuronal postsynaptic membrane, responsible for the clustering and localization of glycine and GABA receptors at inhibitory synapses.	Glycine	150-157	gephyrin	Homo sapiens	4-8
16511656-5	2006	Thus, we propose that two biophysical mechanisms are responsible for saccade slowing after OPN lesions: reduced T-current and reduced NMDA current, both of which are caused by the loss of glycine from OPNs.	Glycine	188-195	secreted phosphoprotein 1	Homo sapiens	91-94
15276154-1	2004	The glycine transporter subtype 2 (GlyT2) is localized at glycinergic axon terminals where it mediates the re-uptake of glycine from the extracellular space.	Glycine	4-11	solute carrier family 6 member 5	Rattus norvegicus	35-40
23393157-1	2013	The GPHN gene codes for gephyrin, a key scaffolding protein in the neuronal postsynaptic membrane, responsible for the clustering and localization of glycine and GABA receptors at inhibitory synapses.	Glycine	150-157	gephyrin	Homo sapiens	24-32
23418741-5	2013	Mutating six consecutive residues in the conserved hinge to glycine strongly abates heparin binding and midkine embryogenic activity.	Glycine	60-67	midkine a	Danio rerio	104-111
15123654-0	2004	Single nucleotide polymorphism (-468 Gly to A) at the promoter region of SREBP-1c associates with genetic defect of fructose-induced hepatic lipogenesis [corrected].	Glycine	37-40	sterol regulatory element binding transcription factor 1	Mus musculus	73-81
16392833-2	2006	The gas-phase structure of tyrosine-glycine varies qualitatively between B3LYP and MP2 optimizations, producing different close contacts between the tyrosine ring and the glycine moiety.	Glycine	36-43	tryptase pseudogene 1	Homo sapiens	83-86
16392833-2	2006	The gas-phase structure of tyrosine-glycine varies qualitatively between B3LYP and MP2 optimizations, producing different close contacts between the tyrosine ring and the glycine moiety.	Glycine	171-178	tryptase pseudogene 1	Homo sapiens	83-86
15181470-4	2004	Glycine N-methyltransferase exhibits Michaelis-Menten kinetics for its substrates, S-adenosylmethionine and glycine, respectively.	Glycine	108-115	glycine N-methyltransferase	Oryctolagus cuniculus	0-27
23335589-2	2013	It is caused by heterozygous germline HRAS mutations mostly affecting Gly(12) or Gly(13), which impair HRAS-GTPase activity and result in increased downstream signal flow independent of incoming signals.	Glycine	70-73	HRas proto-oncogene, GTPase	Homo sapiens	38-42
16475710-3	2006	The mutant alleles of CYP2C9 were residue 144 (Arg (*1)/Cys (*2)), residue 358 (Tyr/Cys), residue 359 (Ile/Leu (*3)) and residue 417 (Gly/Asp).	Glycine	134-137	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	22-28
15159536-1	2004	N-methyl-d-aspartate receptor (NMDAR) activation requires both the binding of glutamate to its recognition site and occupancy of the strychnine insensitive glycine modulatory site (GMS).	Glycine	156-163	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	0-29
23335589-2	2013	It is caused by heterozygous germline HRAS mutations mostly affecting Gly(12) or Gly(13), which impair HRAS-GTPase activity and result in increased downstream signal flow independent of incoming signals.	Glycine	70-73	HRas proto-oncogene, GTPase	Homo sapiens	103-107
15159536-1	2004	N-methyl-d-aspartate receptor (NMDAR) activation requires both the binding of glutamate to its recognition site and occupancy of the strychnine insensitive glycine modulatory site (GMS).	Glycine	156-163	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	31-36
15159536-2	2004	Pharmacological studies suggest that the glycine transporter, GlyT1, maintains subsaturating concentrations of glycine at synaptic NMDARs.	Glycine	41-48	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	62-67
23335589-2	2013	It is caused by heterozygous germline HRAS mutations mostly affecting Gly(12) or Gly(13), which impair HRAS-GTPase activity and result in increased downstream signal flow independent of incoming signals.	Glycine	81-84	HRas proto-oncogene, GTPase	Homo sapiens	38-42
15159536-7	2004	In acute hippocampal slices, exogenous glycine or d-serine (10 microM) enhanced NMDAR currents with Schaffer collateral stimulation in WT mice but not HZ mice, suggesting that the GMS was more occupied in the latter.	Glycine	39-46	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	80-85
23335589-2	2013	It is caused by heterozygous germline HRAS mutations mostly affecting Gly(12) or Gly(13), which impair HRAS-GTPase activity and result in increased downstream signal flow independent of incoming signals.	Glycine	81-84	HRas proto-oncogene, GTPase	Homo sapiens	103-107
23295391-14	2013	Taken together, sunifiram ameliorates OBX-induced deficits of memory-related behaviors and impaired LTP in the hippocampal CA1 region via stimulation of glycine-binding site of NMDAR.	Glycine	153-160	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	177-182
28516014-7	2013	We designed this approach and then validated its efficacy using a 24 amino acid minimum binding region of the intrinsically disordered, neuron-specific substrates, Neurogranin and Neuromodulin, joined via a Gly-linker to their interacting partner, Calmodulin.	Glycine	207-210	growth associated protein 43	Homo sapiens	180-192
15031290-2	2004	The GLYT1 subtypes of glycine transporters (GLYTs) are responsible for regulation of glycine at excitatory synapses, whereas a combination of GLYT1 and GLYT2 subtypes of glycine transporters are used at inhibitory glycinergic synapses.	Glycine	22-29	solute carrier family 6 member 9 L homeolog	Xenopus laevis	4-9
15031290-2	2004	The GLYT1 subtypes of glycine transporters (GLYTs) are responsible for regulation of glycine at excitatory synapses, whereas a combination of GLYT1 and GLYT2 subtypes of glycine transporters are used at inhibitory glycinergic synapses.	Glycine	22-29	solute carrier family 6 member 9 L homeolog	Xenopus laevis	142-147
23457265-3	2013	tardbp mutants show no phenotype, a result of compensation by a unique splice variant of tardbpl that additionally contains a C-terminal elongation highly homologous to the glycine-rich domain of tardbp.	Glycine	173-180	TAR DNA binding protein b	Danio rerio	0-6
23457265-3	2013	tardbp mutants show no phenotype, a result of compensation by a unique splice variant of tardbpl that additionally contains a C-terminal elongation highly homologous to the glycine-rich domain of tardbp.	Glycine	173-180	TAR DNA binding protein b	Danio rerio	89-95
23280365-5	2013	The structural basis for this discrepancy was identified as a single amino acid variation between hCD1d and mCD1d, a glycine-to-tryptophan modification within the alpha2-helix that prevents flattening of the iGb3 headgroup upon TCR ligation.	Glycine	117-124	CD1d molecule	Homo sapiens	98-103
23129207-4	2013	More striking changes were observed when dfc seedlings were grown under N-limited conditions, including shorter primary roots, fewer lateral roots, higher levels of glycine and carbon-N ratios, and lower N content than those in wild-type seedlings.	Glycine	165-172	DHFS-FPGS homolog C	Arabidopsis thaliana	41-44
23295485-4	2013	To obtain homogeneous hMTH1, the Gly at the second position was replaced by Lys.	Glycine	33-36	nudix hydrolase 1	Homo sapiens	22-27
23956997-1	2013	Alanine-glyoxylate aminotransferase catalyzes the transamination between L-alanine and glyoxylate to produce pyruvate and glycine using pyridoxal 5"-phosphate (PLP) as cofactor.	Glycine	122-129	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	0-35
23484211-2	2013	Based on these estimations, a three-dimensional model of Lys-Glu and Ala-Glu-Asp-Gly peptide interactions with DNA sites (GCAG and ATTTC) located in the promoter zones of genes encoding CD5, IL-2, MMP2, and Tram1 signal molecules.	Glycine	81-84	CD5 molecule	Homo sapiens	186-189
23326329-2	2013	Here we demonstrate that protein SUMOylation is required for insertion of the GluA1 AMPAR subunit following transient glycine-evoked increase in AMPA receptor surface expression (ChemLTP) in dispersed neuronal cultures.	Glycine	118-125	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	78-83
24052731-6	2012	We identified two patients with candidate mutations: m.6852G&gt;A that produces an amino acid change of glycine to serine in the MT-CO1 gene and m.8033A&gt;G (Ile Val) in the MT-CO2 gene.	Glycine	104-111	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	129-135
23054484-3	2012	Glycine is the smallest amino acid and the glycyl-tRNA synthetase (GlyRS) belongs to Class II AARSs.	Glycine	0-7	glycyl-tRNA synthetase 1	Homo sapiens	67-72
22628213-3	2012	The two-spidroin (MaSp) model suggests that spider major ampullate (MA) silk is composed of two proteins-MaSp1 predominately contains alanine and glycine and forms strength enhancing beta-sheet crystals, while MaSp2 contains proline and forms elastic spirals.	Glycine	146-153	MBL associated serine protease 1	Homo sapiens	105-110
22341128-1	2012	BACKGROUND: Glycine is a major inhibitory neurotransmitter in the spinal cord, the concentration of which is regulated by two types of glycine transporters (GlyTs): GlyT1 and GlyT2.	Glycine	12-19	solute carrier family 6 member 5	Rattus norvegicus	175-180
22341128-13	2012	CONCLUSIONS: These results indicate that GlyT2 plays a major role in the clearance of extracellular glycine in the spinal cord and that GlyT2 inhibition leads to amelioration of CYP-induced bladder overactivity and pain behavior.	Glycine	100-107	solute carrier family 6 member 5	Rattus norvegicus	41-46
22763616-5	2012	These strains have reciprocally altered NMDA receptor co-agonists, D-serine and glycine, levels that result in decreased (SR-/-) or increased (GlyT1-/+) NMDA receptor signaling.	Glycine	80-87	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	143-148
22712484-4	2012	Significant exchanges occur in acidic media in GSH at positions Glu-beta and Glu-gamma, in Phe-Cys-Gly at positions Phe ortho, Phe-beta, Cys-alpha, Cys-beta, and Gly-alpha, and in His-Cys-Gly at positions His H1, His H2, His beta, Cys beta, and Gly alpha.	Glycine	99-102	histamine receptor H1	Homo sapiens	205-211
22847422-5	2012	Here we present crystal structures of Hsp47 in its free form and in complex with homotrimeric synthetic collagen model peptides, each comprising one Hsp47-binding site represented by an arginine at the Yaa-position of a Xaa-Yaa-Gly triplet.	Glycine	228-231	serine (or cysteine) peptidase inhibitor, clade H, member 1	Mus musculus	38-43
22592312-1	2012	NMDA receptor (NMDAR) activation requires coincident binding of the excitatory neurotransmitter glutamate and a coagonist, either glycine or D-serine.	Glycine	130-137	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	0-13
22592312-1	2012	NMDA receptor (NMDAR) activation requires coincident binding of the excitatory neurotransmitter glutamate and a coagonist, either glycine or D-serine.	Glycine	130-137	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	15-20
22787684-0	2004	(64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu Epidermal growth factor (EGF) is a growth factor composed of 53 amino acids (6.2 kDa), and it is secreted by ectodermic cells, monocytes, kidneys, and duodenal glands (1).	Glycine	50-53	epidermal growth factor	Homo sapiens	87-116
22787684-0	2004	(64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu Epidermal growth factor (EGF) is a growth factor composed of 53 amino acids (6.2 kDa), and it is secreted by ectodermic cells, monocytes, kidneys, and duodenal glands (1).	Glycine	58-61	epidermal growth factor	Homo sapiens	87-116
22473615-3	2012	Two-electrode voltage-clamp electrophysiology in Xenopus laevis oocytes was used to compare the enhancing effects of ethanol, anesthetics, and inhalants on human homomeric alpha1-GlyR activated by saturating concentrations of glycine versus taurine.	Glycine	226-233	glycine receptor alpha 1	Homo sapiens	172-183
16236030-3	2005	We have mutated individual conserved glycine residues and determined their effect on the ATP sensitivity and time-course of P2X1 receptors expressed in Xenopus oocytes.	Glycine	37-44	purinergic receptor P2X, ligand gated ion channel, 1 L homeolog	Xenopus laevis	124-128
22609571-3	2012	d-Serine is synthesized endogenously by serine racemase and modulates NMDAR-mediated synaptic transmission as a coagonist of glycine binding site.	Glycine	125-132	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	70-75
22538654-1	2012	Replacement of glycine 227 in the fifth WD40 motif of alpha-COP/Ret1p/Soo1p by charged or aromatic amino acids is responsible for the temperature-dependent osmo-sensitivity of Saccharomyces cerevisiae, while truncations of WD40 motifs exerted a reduction in cell growth rate and impairment in assembly of cell-wall associated proteins such as enolase and Gas1p.	Glycine	15-22	DNA-directed RNA polymerase III core subunit RET1	Saccharomyces cerevisiae S288C	64-69
22538654-1	2012	Replacement of glycine 227 in the fifth WD40 motif of alpha-COP/Ret1p/Soo1p by charged or aromatic amino acids is responsible for the temperature-dependent osmo-sensitivity of Saccharomyces cerevisiae, while truncations of WD40 motifs exerted a reduction in cell growth rate and impairment in assembly of cell-wall associated proteins such as enolase and Gas1p.	Glycine	15-22	1,3-beta-glucanosyltransferase GAS1	Saccharomyces cerevisiae S288C	355-360
22331412-6	2012	Alanine substitutions of predicted myristoylation (glycine-2) and palmitoylation (cysteine-4) residues affected RPS5 PM localization, protein stability, and function in an additive manner, indicating that PM localization is essential to RPS5 function.	Glycine	51-58	Disease resistance protein (CC-NBS-LRR class) family	Arabidopsis thaliana	112-116
22262856-7	2012	Subsite +1 analysis revealed three residues (Ala-2249, Gly-2250, and Phe-2214) that are specific to DeltaN(123)-GBD-CD2.	Glycine	55-58	CD2 molecule	Homo sapiens	116-119
22220685-1	2012	Serine hydroxymethyltransferase (SHMT) catalyzes the transfer of a beta-carbon from serine to tetrahydrofolate to form glycine and 5,10-methylene-tetrahydrofolate.	Glycine	119-126	serine hydroxymethyltransferase 1	Homo sapiens	0-31
22220685-1	2012	Serine hydroxymethyltransferase (SHMT) catalyzes the transfer of a beta-carbon from serine to tetrahydrofolate to form glycine and 5,10-methylene-tetrahydrofolate.	Glycine	119-126	serine hydroxymethyltransferase 1	Homo sapiens	33-37
22170566-0	2012	Glycine insertion at protease cleavage site of SNAP25 resists cleavage but enhances affinity for botulinum neurotoxin serotype A.	Glycine	0-7	synaptosome associated protein 25	Homo sapiens	47-53
22170566-9	2012	Two of the Gly-insertion mutants exhibited 10-fold lower IC50 values than the wildtype 66-mer SNAP25 peptide.	Glycine	11-14	synaptosome associated protein 25	Homo sapiens	94-100
21826105-2	2012	MRE11 is known to be arginine methylated by PRMT1 within its glycine-arginine-rich (GAR) motif.	Glycine	61-68	protein arginine N-methyltransferase 1	Mus musculus	44-49
22236003-8	2012	Our results show that glycine, histidine and cysteine can inhibit NF-kappaB activation, IkappaBalpha degradation, CD62E expression and IL-6 production in HCAECs, suggesting that these amino acids may exhibit anti-inflammatory effects during endothelial inflammation.	Glycine	22-29	selectin E	Homo sapiens	114-119
24349908-0	2012	Flexible xxx-asp/asn and gly-xxx residues of equine cytochrome C in matrix-assisted laser desorption/ionization in-source decay mass spectrometry.	Glycine	25-28	cytochrome c, somatic	Equus caballus	52-64
24349908-2	2012	Residues more susceptible to MALDI-ISD, namely Xxx-Asp/Asn and Gly-Xxx, were identified from the discontinuous intense peak of c"-ions originating from specific cleavage at N-Calpha bonds of the backbone of equine cytochrome c.	Glycine	63-66	cytochrome c, somatic	Equus caballus	214-226
15081878-2	2004	In the patch-clamp assay, the alpha1 GlyR exhibited the properties expected from a strychnine-sensitive glycine-gated chloride channel.	Glycine	104-111	glycine receptor alpha 1	Homo sapiens	30-41
24349908-5	2012	The MALDI-ISD spectrum of equine cytochrome c gave not only intense N-terminal side c"-ions originating from N-Calpha bond cleavage at Xxx-Asp/Asn and Gly-Xxx residues, but also C-terminal side complement z"-ions originating from the same cleavage sites.	Glycine	151-154	cytochrome c, somatic	Equus caballus	33-45
22432029-1	2012	Localization of CAP-Gly proteins such as CLIP170 at microtubule+ends results from their dual interaction with alpha-tubulin and EB1 through their C-terminal amino acids -EEY.	Glycine	20-23	tubulin alpha 1b	Homo sapiens	110-123
14715656-8	2004	Both ADAMTS-4 and ADAMTS-5 cleaved alpha(2)M at Met(690)/Gly(691), representing a novel proteinase cleavage site within alpha(2)M and a novel site of cleavage for ADAMTS-4 and ADAMTS-5.	Glycine	57-60	alpha-2-macroglobulin	Homo sapiens	35-44
22272310-2	2012	The presynaptic glycine transporter, GlyT2, is required for sustained glycinergic transmission through presynaptic reuptake and recycling of glycine.	Glycine	16-23	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	37-42
14761940-6	2004	The interaction between Rsp5 and Rvs167 is mediated through Rsp5 WW domains and PXY motifs in the central Gly-Pro-Ala-rich domain of Rvs167.	Glycine	106-109	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	24-28
15100740-3	2004	The recombinant and mutant polypeptide was a fragment of COL4A5, containing 158 amino acid residues with a glycine to valine substitution mutation in it.	Glycine	107-114	collagen type IV alpha 5 chain	Homo sapiens	57-63
21501141-6	2011	SLC36A2 is expressed at the apical surface of the human renal proximal tubule where it functions in the reabsorption of glycine, proline and hydroxyproline.	Glycine	120-127	solute carrier family 36 member 2	Homo sapiens	0-7
21681855-3	2011	In a four-generation Chinese family with congenital nuclear pulverulent and posterior polar cataracts, we detected a heterozygous c.5G&gt;A transition in the second exon of GJA3, resulting in the substitution of a highly conserved glycine with aspartic acid (p.G2D) at the N-terminus of the connexin46 (Cx46) protein.	Glycine	231-238	gap junction protein alpha 3	Homo sapiens	173-177
15041686-2	2004	Dichroism measurements of single, isotopically enhanced vibrational modes (e.g., Amide I 13C=18O or Gly CD2 stretching modes) can yield precise orientational restraints for the monomer helix protomer that can be used as refinement constraints in model building of the entire helical bundle.	Glycine	100-103	CD2 molecule	Homo sapiens	104-107
14702345-5	2004	Partial restoration of (R31D/R32D)-Crp4 bactericidal activity occurred when an electropositive Arg for Gly substitution was introduced at the peptide N terminus and the (G1R/R31D/R32D)-Crp4 peptide exhibited intermediate membrane binding capability.	Glycine	103-106	defensin, alpha, 20	Mus musculus	35-39
14988435-2	2004	The synthesis of GSH from glutamate, cysteine, and glycine is catalyzed sequentially by two cytosolic enzymes, gamma-glutamylcysteine synthetase and GSH synthetase.	Glycine	51-58	glutathione synthetase	Homo sapiens	149-163
21681855-3	2011	In a four-generation Chinese family with congenital nuclear pulverulent and posterior polar cataracts, we detected a heterozygous c.5G&gt;A transition in the second exon of GJA3, resulting in the substitution of a highly conserved glycine with aspartic acid (p.G2D) at the N-terminus of the connexin46 (Cx46) protein.	Glycine	231-238	gap junction protein alpha 3	Homo sapiens	291-301
21681855-3	2011	In a four-generation Chinese family with congenital nuclear pulverulent and posterior polar cataracts, we detected a heterozygous c.5G&gt;A transition in the second exon of GJA3, resulting in the substitution of a highly conserved glycine with aspartic acid (p.G2D) at the N-terminus of the connexin46 (Cx46) protein.	Glycine	231-238	gap junction protein alpha 3	Homo sapiens	303-307
21633974-0	2011	Chronically saturating levels of endogenous glycine disrupt glutamatergic neurotransmission and enhance synaptogenesis in the CA1 region of mouse hippocampus.	Glycine	44-51	carbonic anhydrase 1	Mus musculus	126-129
14670964-3	2004	We have shown that inactivation of MMP-7 (matrilysin) by HOCl coincides with the formation of a novel oxidation product, WG-4, through modification of adjacent tryptophan and glycine residues and loss of 4 atomic mass units.	Glycine	175-182	matrix metallopeptidase 7	Homo sapiens	35-40
14670964-3	2004	We have shown that inactivation of MMP-7 (matrilysin) by HOCl coincides with the formation of a novel oxidation product, WG-4, through modification of adjacent tryptophan and glycine residues and loss of 4 atomic mass units.	Glycine	175-182	matrix metallopeptidase 7	Homo sapiens	42-52
14746492-3	2004	MP2/6-311++G** calculations were also carried out for Gly/Ala peptides.	Glycine	54-57	tryptase pseudogene 1	Homo sapiens	0-3
12750892-3	2004	VIAAT exchanges GABA or glycine for protons.	Glycine	24-31	solute carrier family 32 member 1	Homo sapiens	0-5
14600155-2	2004	PAT2 and its paralog, PAT1/LYAAT-1, are transporters for small amino acids such as glycine, alanine, and proline.	Glycine	83-90	solute carrier family 36 member 2	Homo sapiens	0-4
14600155-2	2004	PAT2 and its paralog, PAT1/LYAAT-1, are transporters for small amino acids such as glycine, alanine, and proline.	Glycine	83-90	solute carrier family 36 member 1	Homo sapiens	22-26
14600155-2	2004	PAT2 and its paralog, PAT1/LYAAT-1, are transporters for small amino acids such as glycine, alanine, and proline.	Glycine	83-90	solute carrier family 36 member 1	Homo sapiens	27-34
14600155-8	2004	Transport of amino acids by PAT2 activity is dependent on membrane potential and can occur bidirectionally; membrane depolarization causes net glycine outward currents.	Glycine	143-150	solute carrier family 36 member 2	Homo sapiens	28-32
14600155-9	2004	Our data suggest that PAT2 contributes to neuronal transport and sequestration of amino acids such as glycine, alanine, and/or proline, whereby the transport direction is dependent on the sum of the driving forces such as substrate concentration, pH gradient, and membrane potential.	Glycine	102-109	solute carrier family 36 member 2	Homo sapiens	22-26
14672656-3	2004	This glycine residue, at the strand/loop junction of beta3/loop3, is found in U1A RBD1, and in most RBD domains, suggesting it has a specific role in modulation of RNA binding.	Glycine	5-12	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	53-64
14997472-4	2004	The fibronectin active sequence GRGDS (FN) or a scrambled sequence RSGGD (SC) were conjugated to either A208 or to A208S (AASVVIAKSADR), a scrambled peptide of A208, with a glycine as a spacer.	Glycine	173-180	fibronectin 1	Mus musculus	4-15
14992262-3	2004	In particular, intracellular chloride activity and hence the neuronal response to GABA and glycine appears to be determined by a balance between chloride efflux and influx through KCC2 and the Na+-K+-2Cl- cotransporter NKCC1, respectively.	Glycine	91-98	solute carrier family 12 member 2	Homo sapiens	219-224
14504280-5	2003	The structure of the Mtr2-Mex67 NTF2-like domain complex, which overall is similar to those of the human and Saccharomyces cerevisiae homologs, unveils three putative Phe-Gly repeat binding sites, of which one contributes to the heterodimer interface.	Glycine	171-174	Ran GTPase-binding protein NTF2	Saccharomyces cerevisiae S288C	32-36
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	119-122	thioredoxin	Homo sapiens	34-45
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	119-122	thioredoxin	Homo sapiens	47-50
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	119-122	thioredoxin	Homo sapiens	64-67
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	131-134	thioredoxin	Homo sapiens	34-45
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	131-134	thioredoxin	Homo sapiens	47-50
14569031-2	2003	All known isoenzymes of mammalian thioredoxin (Trx) reductases (TrxRs) employ selenium in the C-terminal redox center -Gly-Cys-Sec-Gly-COOH for reduction of Trx and other substrates, whereas the corresponding sequence in Drosophila melanogaster TrxR is -Ser-Cys-Cys-Ser-COOH.	Glycine	131-134	thioredoxin	Homo sapiens	64-67
16131614-3	2005	Key residues were selected for mutation based on ligand-protein docking studies using a homology model of NR2B-S1S2 built from the X-ray structure of NR1-S1S2 in complex with glycine.	Glycine	175-182	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	106-110
16131614-3	2005	Key residues were selected for mutation based on ligand-protein docking studies using a homology model of NR2B-S1S2 built from the X-ray structure of NR1-S1S2 in complex with glycine.	Glycine	175-182	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	150-153
15979761-0	2005	Recombinant prohormone convertase 1 and 2 cleave purified pro cholecystokinin (CCK) and a synthetic peptide containing CCK 8 Gly Arg Arg and the carboxyl-terminal flanking peptide.	Glycine	125-128	proprotein convertase subtilisin/kexin type 1	Homo sapiens	12-41
16043285-0	2005	Morphological evidence for GABA/glycine-cocontaining terminals in synaptic contact with neurokinin-1 receptor-expressing neurons in the sacral dorsal commissural nucleus of the rat.	Glycine	32-39	tachykinin receptor 1	Rattus norvegicus	88-109
16043285-1	2005	Previous studies have shown that neurons in the sacral dorsal commissural nucleus (SDCN) express neurokinin-1 receptor (NK1R) and can be modulated by the co-release of GABA and glycine (Gly) from single presynaptic terminal.	Glycine	177-184	tachykinin receptor 1	Rattus norvegicus	97-118
16043285-1	2005	Previous studies have shown that neurons in the sacral dorsal commissural nucleus (SDCN) express neurokinin-1 receptor (NK1R) and can be modulated by the co-release of GABA and glycine (Gly) from single presynaptic terminal.	Glycine	177-184	tachykinin receptor 1	Rattus norvegicus	120-124
16043285-1	2005	Previous studies have shown that neurons in the sacral dorsal commissural nucleus (SDCN) express neurokinin-1 receptor (NK1R) and can be modulated by the co-release of GABA and glycine (Gly) from single presynaptic terminal.	Glycine	186-189	tachykinin receptor 1	Rattus norvegicus	97-118
16043285-1	2005	Previous studies have shown that neurons in the sacral dorsal commissural nucleus (SDCN) express neurokinin-1 receptor (NK1R) and can be modulated by the co-release of GABA and glycine (Gly) from single presynaptic terminal.	Glycine	186-189	tachykinin receptor 1	Rattus norvegicus	120-124
16043285-2	2005	These results raise the possibility that GABA/Gly-cocontaining terminals might make synaptic contacts with NK1R-expressing neurons in the SDCN.	Glycine	46-49	tachykinin receptor 1	Rattus norvegicus	107-111
16043285-6	2005	These results suggested that some synaptic terminals upon NK1R-expressing SDCN neurons co-released both GABA and Gly.	Glycine	113-116	tachykinin receptor 1	Rattus norvegicus	58-62
16373326-10	2005	The functional characteristics of rabbit PAT1 in either mammalian cells or renal BBMV suggest that PAT1 is the low-affinity transporter of proline, glycine and hydroxyproline believed to be defective in patients with iminoglycinuria.	Glycine	148-155	solute carrier family 36 member 1	Homo sapiens	99-103
15992384-4	2005	Two of the dat-1 alleles derive from point mutations in conserved glycine residues (G55, G90) in contiguous DAT-1 transmembrane domains (TM1 and TM2, respectively), whereas the third allele results in altered translation of the transporter"s COOH terminus.	Glycine	66-73	Sodium-dependent dopamine transporter	Caenorhabditis elegans	11-16
15992384-4	2005	Two of the dat-1 alleles derive from point mutations in conserved glycine residues (G55, G90) in contiguous DAT-1 transmembrane domains (TM1 and TM2, respectively), whereas the third allele results in altered translation of the transporter"s COOH terminus.	Glycine	66-73	Sodium-dependent dopamine transporter	Caenorhabditis elegans	108-113
15982768-1	2005	Endogenous polyamines like spermine are known to have four distinct effects on recombinant N-methyl-d-aspartate (NMDA) receptor channels: voltage-dependent inhibition, glycine-dependent stimulation, glycine-independent stimulation and decreased affinity to the agonist (l-glutamate).	Glycine	168-175	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	91-127
15982768-1	2005	Endogenous polyamines like spermine are known to have four distinct effects on recombinant N-methyl-d-aspartate (NMDA) receptor channels: voltage-dependent inhibition, glycine-dependent stimulation, glycine-independent stimulation and decreased affinity to the agonist (l-glutamate).	Glycine	199-206	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	91-127
15920480-3	2005	The Adar transcript itself is edited in adult wild-type flies to generate an isoform with a serine to glycine substitution close to the ADAR active site.	Glycine	102-109	Adenosine deaminase acting on RNA	Drosophila melanogaster	4-8
15658938-8	2005	Our functional characterization of PARG residues, along with recent identification of an inhibitor-binding residue Tyr796 and a glycine-rich region Gly745-Gly-Gly747 important for PARG function, allowed us to define a PARG "signature sequence" [vDFA-X3-GGg-X6-8-vQEEIRF-X3-PE-X14-E-X12-YTGYa], which we used to identify putative PARG sequences across a range of organisms.	Glycine	128-135	poly(ADP-ribose) glycohydrolase	Bos taurus	180-184
15658938-8	2005	Our functional characterization of PARG residues, along with recent identification of an inhibitor-binding residue Tyr796 and a glycine-rich region Gly745-Gly-Gly747 important for PARG function, allowed us to define a PARG "signature sequence" [vDFA-X3-GGg-X6-8-vQEEIRF-X3-PE-X14-E-X12-YTGYa], which we used to identify putative PARG sequences across a range of organisms.	Glycine	128-135	poly(ADP-ribose) glycohydrolase	Bos taurus	180-184
15658938-8	2005	Our functional characterization of PARG residues, along with recent identification of an inhibitor-binding residue Tyr796 and a glycine-rich region Gly745-Gly-Gly747 important for PARG function, allowed us to define a PARG "signature sequence" [vDFA-X3-GGg-X6-8-vQEEIRF-X3-PE-X14-E-X12-YTGYa], which we used to identify putative PARG sequences across a range of organisms.	Glycine	128-135	poly(ADP-ribose) glycohydrolase	Bos taurus	180-184
15658938-8	2005	Our functional characterization of PARG residues, along with recent identification of an inhibitor-binding residue Tyr796 and a glycine-rich region Gly745-Gly-Gly747 important for PARG function, allowed us to define a PARG "signature sequence" [vDFA-X3-GGg-X6-8-vQEEIRF-X3-PE-X14-E-X12-YTGYa], which we used to identify putative PARG sequences across a range of organisms.	Glycine	148-151	poly(ADP-ribose) glycohydrolase	Bos taurus	180-184
15658938-8	2005	Our functional characterization of PARG residues, along with recent identification of an inhibitor-binding residue Tyr796 and a glycine-rich region Gly745-Gly-Gly747 important for PARG function, allowed us to define a PARG "signature sequence" [vDFA-X3-GGg-X6-8-vQEEIRF-X3-PE-X14-E-X12-YTGYa], which we used to identify putative PARG sequences across a range of organisms.	Glycine	148-151	poly(ADP-ribose) glycohydrolase	Bos taurus	180-184
15658938-8	2005	Our functional characterization of PARG residues, along with recent identification of an inhibitor-binding residue Tyr796 and a glycine-rich region Gly745-Gly-Gly747 important for PARG function, allowed us to define a PARG "signature sequence" [vDFA-X3-GGg-X6-8-vQEEIRF-X3-PE-X14-E-X12-YTGYa], which we used to identify putative PARG sequences across a range of organisms.	Glycine	148-151	poly(ADP-ribose) glycohydrolase	Bos taurus	180-184
16018252-10	2005	An A was replaced by a G in codon 38 upstream of the 5" border outside the HMG box of the SRY gene, resulting in the replacement of the amino acid glutamate by glycine.	Glycine	160-167	sex determining region Y	Homo sapiens	90-93
15739236-1	2005	Gephyrin is a postsynaptic scaffolding protein involved in clustering of glycine- and GABA(A) receptors at inhibitory synapses.	Glycine	73-80	gephyrin	Homo sapiens	0-8
15909916-2	2005	The mutation C--&gt;T was found in the second exon and led to an amino acid substitution (glycin--&gt;glutamic acid) in the conserved domain of protein kinase encoded by the ABRUPTUS/PINOID (ABR/PID) gene.	Glycine	90-96	Protein kinase superfamily protein	Arabidopsis thaliana	174-189
15909916-2	2005	The mutation C--&gt;T was found in the second exon and led to an amino acid substitution (glycin--&gt;glutamic acid) in the conserved domain of protein kinase encoded by the ABRUPTUS/PINOID (ABR/PID) gene.	Glycine	90-96	Protein kinase superfamily protein	Arabidopsis thaliana	195-198
15615862-2	2005	We have previously reported that a highly conserved glycine residue within linker I is important for constraining the fidelity of receptor recognition by Galpha(q) proteins.	Glycine	52-59	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	154-160
15598649-3	2005	We have recently reported that the lysosomal targeting of CLN3 is facilitated by two targeting motifs: a dileucine-type motif in a cytoplasmic loop domain and an unusual motif in the carboxyl-terminal cytoplasmic tail comprising a methionine and a glycine separated by nine amino acids (Kyttala, A., Ihrke, G., Vesa, J., Schell, M. J., and Luzio, J. P. (2004) Mol.	Glycine	248-255	ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	Mus musculus	58-62
15661817-1	2005	To investigate the effects of persistent elevation of synaptic glycine at Schaffer collateral-CA1 synapses of the hippocampus, we studied the glutamatergic synaptic transmission in acute brain slices from mice with reduced expression of glycine transporter type 1 (GlyT1+/-) as compared to wild type (WT) littermates using whole-cell patch-clamp recordings of CA1 pyramidal cells.	Glycine	63-70	carbonic anhydrase 1	Mus musculus	94-97
15598699-0	2005	Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply.	Glycine	104-111	serine hydroxymethyltransferase 1	Homo sapiens	4-35
15746915-5	2005	Immunohistochemical studies demonstrate synaptic colocalization of the vesicular glutamate transporter 3 with the vesicular GABA transporter, indicating that GABA, glycine and glutamate are released from single MNTB terminals.	Glycine	164-171	solute carrier family 17 member 8	Homo sapiens	71-104
15697204-2	2005	Although most hereditary collagen disorders are rare, a common occurrence of a Gly replacement mutation is found in the collagenous domain of mannose binding lectin (MBL).	Glycine	79-82	mannose binding lectin 2	Homo sapiens	142-164
15697204-2	2005	Although most hereditary collagen disorders are rare, a common occurrence of a Gly replacement mutation is found in the collagenous domain of mannose binding lectin (MBL).	Glycine	79-82	mannose binding lectin 2	Homo sapiens	166-169
15697204-3	2005	A Gly --&gt; Asp mutation at position 54 in MBL is found at a frequency as high as 30% in certain populations and leads to increased susceptibility to infections.	Glycine	2-5	mannose binding lectin 2	Homo sapiens	44-47
15697204-4	2005	The structural and energetic consequences of this mutation are investigated by comparing a triple-helical peptide containing the N-terminal Gly-X-Y units of MBL with the homologous peptide containing the Gly to Asp replacement.	Glycine	140-143	mannose binding lectin 2	Homo sapiens	157-160
15533938-3	2005	In MMP-8, the neutrophil collagenase, a conserved Gly at the S(3)" substrate specificity subsite is replaced by Asn(188) that forms a highly unusual cis bond with Tyr(189), a conserved active site residue in the collagenases.	Glycine	50-53	matrix metallopeptidase 8	Homo sapiens	3-8
15533938-3	2005	In MMP-8, the neutrophil collagenase, a conserved Gly at the S(3)" substrate specificity subsite is replaced by Asn(188) that forms a highly unusual cis bond with Tyr(189), a conserved active site residue in the collagenases.	Glycine	50-53	matrix metallopeptidase 8	Homo sapiens	14-36
15507442-3	2005	We show herein that alanine mutations of N-terminal AID residues Gln(1), Gln(2), Ile(3), Glu(4), Glu(6), Leu(7), and Gly(9) in Ca(V)2.3 did not abolish [(35)S]Ca(V)beta 1b or [(35)S]Ca(V)beta 3 subunit overlay binding to fusion proteins nor did they prevent the typical modulation of whole cell currents by Ca(V)beta 3.	Glycine	117-120	calcium voltage-gated channel subunit alpha1 E	Homo sapiens	127-135
15542821-6	2004	First, a genome-wide yeast two-hybrid screen using Prp2 as bait identified Spp2, which contained a motif with glycine residues found in a number of RNA binding proteins.	Glycine	110-117	secreted phosphoprotein 2	Homo sapiens	75-79
15498669-6	2004	The p-OAc substituent on the C-1 phenyl ring is oriented in a hydrophobic pocket comprised of Met(522), Gly(526), Trp(387), Tyr(348), and Tyr(385), and the C-2 ethyl substituent is oriented towards the mouth of the COX-2 channel in the vicinity of amino acid residues Arg(120), Leu(531), and Val(349).	Glycine	104-107	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	29-32
15485496-0	2004	Differential modulation of evoked and spontaneous glycine release from rat spinal cord glycinergic terminals by the cyclic AMP/protein kinase A transduction cascade.	Glycine	50-57	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	127-143
15198928-4	2004	Quiescent HMC were exposed to 200 microg/ml bovine serum albumin (BSA) or glycated BSA (Gly-BSA) for 12-72 h. At 24 h, Gly-BSA stimulated TGF-beta1 and PAI-1 mRNA expression in HMC to 1.8 and 3.2 times that in the BSA-treated control cells.	Glycine	119-122	serpin family E member 1	Homo sapiens	152-157
15198928-5	2004	Gly-BSA also activated the PAI-1 promoter luciferase activity 2.3-fold.	Glycine	0-3	serpin family E member 1	Homo sapiens	27-32
15198928-10	2004	Transfection of phosphorothioate CAGA oligonucleotide, a CAGA antisense analog, inhibited Gly-BSA-induced PAI-1 mRNA expression.	Glycine	90-93	serpin family E member 1	Homo sapiens	106-111
15198928-11	2004	Cotransfection of phosphorothioate CAGA oligonucleotides with PAI-1 reporter vector also blocked Gly-BSA-induced PAI-1 promoter luciferase activity.	Glycine	97-100	serpin family E member 1	Homo sapiens	62-67
15198928-11	2004	Cotransfection of phosphorothioate CAGA oligonucleotides with PAI-1 reporter vector also blocked Gly-BSA-induced PAI-1 promoter luciferase activity.	Glycine	97-100	serpin family E member 1	Homo sapiens	113-118
15198928-12	2004	These results indicate that Gly-BSA increases DNA binding activity of Smad3 and that it stimulates PAI-1 transcription through Smad-binding CAGA sequences in the PAI-1 promoter in HMC.	Glycine	28-31	serpin family E member 1	Homo sapiens	162-167
15258155-8	2004	The bisphosphoglycerate mutase-specific residue Gly-14 may cause the most important conformational changes, which makes the side chain of Glu-13 orient toward the active site.	Glycine	48-51	bisphosphoglycerate mutase	Homo sapiens	4-30
15302677-4	2004	Comparing the effects of the GlyR agonists, glycine, beta-alanine and taurine, on the GlyR alpha2 isoforms, revealed a significant increase in potency for all three agonists at the alpha2B variant.	Glycine	44-51	adrenergic receptor, alpha 2b	Mus musculus	181-188
15229879-9	2004	The results show that CA(N) residues His87-Ala-Gly-Pro-Ile-Ala92 form the majority of the interactions with CypA residues.	Glycine	47-50	peptidylprolyl isomerase A	Homo sapiens	108-112
15184865-4	2004	Substitution of valine 804 with the small amino- acid glycine renders the RET kinase even more susceptible to inhibition (ZD6474 IC(50): 20 nM) than the wild-type kinase.	Glycine	54-61	ret proto-oncogene	Homo sapiens	74-77
15185339-0	2004	Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel.	Glycine	0-7	gastrin	Homo sapiens	17-24
15185339-0	2004	Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel.	Glycine	0-7	matrix metallopeptidase 1	Homo sapiens	33-67
15185339-1	2004	The effects of glycine-extended gastrin (G-Gly) on the invasion by colon cancer cells through stromal extracellular matrix and the role of metalloproteinases (MMPs) in this invasion were investigated.	Glycine	15-22	gastrin	Homo sapiens	32-39
15377274-5	2004	Analysis by LC/MSD-Trap showed the amino acid sequence of this hexapeptide to be Glu-Ala-Lys-Ser-Gln-Gly-OH with molecular weight 618.5 daltons.	Glycine	101-107	acid phosphatase 5, tartrate resistant	Bos taurus	19-23
15138252-2	2004	Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2.	Glycine	204-207	dual specificity phosphatase 22	Homo sapiens	11-27
15138252-2	2004	Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2.	Glycine	204-207	dual specificity phosphatase 22	Homo sapiens	29-32
15138252-2	2004	Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2.	Glycine	204-207	dual specificity phosphatase 22	Homo sapiens	35-41
15236634-9	2004	Subsequently, glycine supplementation to alcohol-fed rats significantly lowered the activities of serum AST, ALT, ALP, GGT and normalized the liver and brain fatty acid composition compared with untreated alcohol-fed rats.	Glycine	14-21	gamma-glutamyltransferase 1	Rattus norvegicus	119-122
15236634-11	2004	Thus, the present study demonstrates that oral administration of glycine confers a significant protective effect against alcohol-induced hepatotoxicity by virtue of its ability to optimize the activities of serum AST, ALT, ALP and GGT, as well as the tissue fatty acid composition.	Glycine	65-72	gamma-glutamyltransferase 1	Rattus norvegicus	231-234
12941372-1	2003	In the central nervous system, re-uptake of the neurotransmitter glycine is mediated by two different glycine transporters, GlyT1 and GlyT2.	Glycine	65-72	solute carrier family 6 member 5	Rattus norvegicus	134-139
12949723-7	2003	TNBS-induced increases in MPO activities in the colonic tissue were blunted significantly in glycine-fed animals.	Glycine	93-100	myeloperoxidase	Rattus norvegicus	26-29
12756255-7	2003	The fact that a larger side chain at the 680th position suppresses the defects of F482A myosin suggests that the defects are caused by insufficient contact between side chains of Ala-482 and Gly-680.	Glycine	191-194	myosin heavy chain 14	Homo sapiens	88-94
12759346-0	2003	Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation.	Glycine	80-87	matrix metallopeptidase 7	Homo sapiens	124-163
12759346-13	2003	Thus, HOCl inactivates MMP-7, perhaps by site-specific conversion of tryptophan-glycine to WG-4.	Glycine	80-87	matrix metallopeptidase 7	Homo sapiens	23-28
15240653-9	2004	Stratifying subjects according to IRS-1 genotype, we observed that acetylcholine-stimulated forearm blood flow was significantly (P &lt; 0.0001) lower in Gly/Arg heterozygous carriers than in Gly/Gly carriers (11.3 +/- 4.4 vs. 14.7 +/- 5.9 ml/100 ml(-1) of tissue per min(-1)).	Glycine	154-157	insulin receptor substrate 1	Homo sapiens	34-39
21633974-4	2011	The glycine concentration at the synapse is tightly regulated by two types of glycine transporters, GlyT1 and GlyT2, located on nerve terminals or astrocytes.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	100-105
15170323-1	2004	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate serving as the one-carbon carrier.	Glycine	94-101	serine hydroxymethyltransferase 1	Homo sapiens	0-31
21633974-4	2011	The glycine concentration at the synapse is tightly regulated by two types of glycine transporters, GlyT1 and GlyT2, located on nerve terminals or astrocytes.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	110-115
15170323-1	2004	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate serving as the one-carbon carrier.	Glycine	94-101	serine hydroxymethyltransferase 1	Homo sapiens	33-37
21633974-7	2011	The purpose of this investigation is to determine the impact of chronically high concentrations of endogenous glycine on glutamatergic neurotransmission during postnatal development using an in vivo mouse model (GlyT1+/-).	Glycine	110-117	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	212-217
21621561-4	2011	Here, we show that the Ala or Gly-extended GLP-1/IgG-Fc fusion protein is resistant to DPP-IV and has increased half-life in vivo.	Glycine	30-33	dipeptidylpeptidase 4	Mus musculus	87-93
15118906-5	2004	The results suggest that certain conserved glycine residues in the second and third conserved regions of Imp1 and Imp2 are important for stabilisation of the Imp complex and for the proteolytic activity of the subunits, respectively.	Glycine	43-50	endopeptidase catalytic subunit IMP1	Saccharomyces cerevisiae S288C	105-109
15118906-5	2004	The results suggest that certain conserved glycine residues in the second and third conserved regions of Imp1 and Imp2 are important for stabilisation of the Imp complex and for the proteolytic activity of the subunits, respectively.	Glycine	43-50	endopeptidase catalytic subunit	Saccharomyces cerevisiae S288C	114-118
21507951-1	2011	Gephyrin is a scaffold protein essential for stabilizing glycine and GABA(A) receptors at inhibitory synapses.	Glycine	57-64	gephyrin	Homo sapiens	0-8
12710888-5	2003	A notable feature of XlGSTP1-1 is the presence in the H-site of Phe(111) and Pro(208) in place of tyrosine and glycine residues respectively, present in other mammalian Pi-class GSTs.	Glycine	111-118	glutathione S-transferase pi 1 L homeolog	Xenopus laevis	21-30
12684523-1	2003	Gephyrin (GPHN) is an organizational protein that clusters and localizes the inhibitory glycine (GlyR) and GABAA receptors to the microtubular matrix of the neuronal postsynaptic membrane.	Glycine	88-95	gephyrin	Homo sapiens	0-8
15147195-1	2004	The prolyl isomerase cyclophilin A (CypA) is required for efficient HIV-1 replication and is incorporated into virions through a binding interaction at the Gly-Pro(222) bond located within the capsid domain of the HIV-1 Gag precursor polyprotein (Pr(gag)).	Glycine	156-159	peptidylprolyl isomerase A	Homo sapiens	36-40
21393249-6	2011	Using affinity chromatography and mass spectrometry, we identify sarcosine dehydrogenase (SARDH), the enzyme that converts sarcosine to glycine, as a TMEFF2-interacting protein.	Glycine	136-143	transmembrane protein with EGF like and two follistatin like domains 2	Homo sapiens	150-156
15147195-3	2004	To address the proposal that CypA interacts with Gly-Pro sequences in the C-terminal domain of a mature capsid, the interaction between CypA and the natively folded, full-length capsid protein (CA(FL)) has been investigated here using nuclear magnetic resonance spectroscopy.	Glycine	49-52	peptidylprolyl isomerase A	Homo sapiens	29-33
15150094-0	2004	Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.	Glycine	54-61	B-Raf proto-oncogene, serine/threonine kinase	Rattus norvegicus	48-53
12684523-1	2003	Gephyrin (GPHN) is an organizational protein that clusters and localizes the inhibitory glycine (GlyR) and GABAA receptors to the microtubular matrix of the neuronal postsynaptic membrane.	Glycine	88-95	gephyrin	Homo sapiens	10-14
15150094-4	2004	In this study, we examined the effect of colon tumor-associated mutations within the B-Raf glycine-rich loop (G loop) on MEK/Erk and NFkappaB signaling and on the transformation of NIH3T3 fibroblasts or IEC-6 intestinal epithelial cells.	Glycine	91-98	B-Raf proto-oncogene, serine/threonine kinase	Rattus norvegicus	85-90
12662155-7	2003	The active-site serine residue is replaced by a glycine residue in DPP10, resulting in the loss of DPP activity.	Glycine	48-55	dipeptidyl peptidase like 10	Homo sapiens	67-72
21122942-8	2011	Finally, RNAi-mediated silencing of GlyRalpha1 abolished the glycine-induced changes in phosphorylation status of the above kinases in ATP-depleted cells.	Glycine	61-68	glycine receptor alpha 1	Homo sapiens	36-46
21295405-8	2011	These findings imply that chronic pain has a crucial influence on hippocampal plasticity related to cognitive function, and strongly suggest that increasing the extracellular level of glycine via blockade of GlyT1 is a potential therapeutic approach for chronic pain with memory impairment.	Glycine	184-191	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	208-213
12781915-2	2003	In the present study, the effects of bupivacaine and ropivacaine on ion currents induced by glycine and glutamate in acutely dissociated hippocampal CA1 neurons of rats were investigated via a nystatin-perforated patch clamping method at a clamped voltage.	Glycine	92-99	carbonic anhydrase 1	Rattus norvegicus	149-152
14981077-4	2004	A substituted cysteine accessibility analysis demonstrated previously that glycine binding induced an increase in surface accessibility of all residues from Arg(271) to Lys(276) in the M2-M3 domain of the homomeric alpha1 GlyR.	Glycine	75-82	glycine receptor alpha 1	Homo sapiens	215-226
21295405-10	2011	Increasing the extracellular level of glycine via blockade of GlyT1 is a potential therapeutic approach for chronic pain with memory impairment.	Glycine	38-45	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	62-67
21044902-5	2011	Modelling of the mutant protein reveals a steric clash with the kinase domain that will weaken interactions with FKBP12 and induce exposure of the glycine/serine-rich repeat.	Glycine	147-154	FKBP prolyl isomerase 1A pseudogene 1	Homo sapiens	113-119
15121838-0	2004	Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2.	Glycine	26-33	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	82-85
15121838-5	2004	To attempt to identify potential substrates for XT2, we screened urine from XT2-knockout mice by high-pressure liquid chromatography and mass spectrometry and found significantly elevated concentrations of glycine.	Glycine	206-213	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	48-51
15121838-5	2004	To attempt to identify potential substrates for XT2, we screened urine from XT2-knockout mice by high-pressure liquid chromatography and mass spectrometry and found significantly elevated concentrations of glycine.	Glycine	206-213	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	76-79
15121838-7	2004	After 2 h, XT2(-/-) mice were found to excrete almost twice as much glycine as the XT2(+/+) controls (P = 0.03).	Glycine	68-75	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	11-14
15121838-12	2004	Glycine loading caused systolic blood pressure to fall in the XT2(-/-) mice from 127 +/- 3 to 115 +/- 3 mmHg (P &lt; 0.001), a level virtually identical to that of the wild-type controls.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	62-65
15121838-13	2004	These data suggest that the XT2 orphan transporter is involved in glycine reabsorption and that the absence of this transporter is sufficient to cause hypertension.	Glycine	66-73	solute carrier family 6 (neurotransmitter transporter), member 18	Mus musculus	28-31
12780388-6	2003	RESULTS: Basolateral application of EGF increased [14C]Gly-Sar uptake with an ED50 value of 0.77 +/- 0.25 ng mL-1 (n = 3-6) and a maximal stimulation of 33 +/- 2% (n = 3-6).	Glycine	55-58	epidermal growth factor	Homo sapiens	36-39
21364044-5	2011	The high number of bioactive fragments in collagen and elastin is associated with a high content of glycine and proline, amino acids that are most abundant in biologically active fragments.	Glycine	100-107	elastin	Bos taurus	55-62
12773175-2	2003	The Toll-like receptor 4 ( TLR4 ) Asp-299--&gt;Gly polymorphism has been shown to reduce lipopolysaccharide responsiveness.	Glycine	47-50	toll like receptor 4	Homo sapiens	4-24
12773175-2	2003	The Toll-like receptor 4 ( TLR4 ) Asp-299--&gt;Gly polymorphism has been shown to reduce lipopolysaccharide responsiveness.	Glycine	47-50	toll like receptor 4	Homo sapiens	27-31
14970226-10	2004	Conversely, mutating the moderately conserved residue (Gly-346) abrogated gp120 binding but enhanced ICAM-2 and ICAM-3 binding.	Glycine	55-58	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	74-79
14970226-10	2004	Conversely, mutating the moderately conserved residue (Gly-346) abrogated gp120 binding but enhanced ICAM-2 and ICAM-3 binding.	Glycine	55-58	intercellular adhesion molecule 2	Homo sapiens	101-107
21282399-2	2011	The single-channel activity of homomeric alpha2 channels differs from that of alpha1-containing GlyRs, as even at the lowest glycine concentration (20 microM), openings occurred in long (&gt;300-ms) groups with high open probability (P(open); 0.96; cell-attached recordings, HEK-expressed channels).	Glycine	125-132	adrenoceptor alpha 1D	Homo sapiens	78-84
15005607-3	2004	The structure of the peptide consisted of a well-defined beta-turn between Gly(13) and Asp(16) of gastrin.	Glycine	75-78	gastrin	Homo sapiens	98-105
15094652-4	2004	Glycine was found elevated in CSF.	Glycine	0-7	colony stimulating factor 2	Homo sapiens	30-33
15094652-5	2004	This pattern of clinical history, MR imaging and spectroscopy features and elevated glycine in CSF is characteristic for a novel entity amongst the leukoencephalopathies of childhood.	Glycine	84-91	colony stimulating factor 2	Homo sapiens	95-98
14645232-1	2004	Glycine specifically induces genes encoding subunits of the glycine decarboxylase complex (GCV1, GCV2, and GCV3), and this is mediated by a fall in cytoplasmic levels of 5,10-methylenetetrahydrofolate caused by inhibition of cytoplasmic serine hydroxymethyltransferase.	Glycine	0-7	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	97-101
12748860-4	2004	Both PAT1 and PAT2 mediate 1:1 symport of protons and small neutral amino acids such as glycine, alanine, and proline.	Glycine	88-95	solute carrier family 36 member 1	Homo sapiens	5-9
12748860-4	2004	Both PAT1 and PAT2 mediate 1:1 symport of protons and small neutral amino acids such as glycine, alanine, and proline.	Glycine	88-95	solute carrier family 36 member 2	Homo sapiens	14-18
14662146-7	2004	The folic acid+glycine supplement tended (P&lt;0.07) to increase allantoic content of PGE2 and TGF-beta2 in all sows and increased (P&lt;0.05) endometrial expression of COX2, especially in NYL sows.	Glycine	15-22	transforming growth factor beta 2	Sus scrofa	95-104
14662146-8	2004	The endometrial expression of COX1 was decreased (P&lt;0.05) by folic acid+glycine supplement, especially in multiparous YL sows.	Glycine	75-82	cytochrome c oxidase subunit I	Sus scrofa	30-34
14745783-8	2004	Additional disruption of AGX1 revealed a complete glycine auxotrophy.	Glycine	50-57	alanine--glyoxylate transaminase	Saccharomyces cerevisiae S288C	25-29
14729624-0	2004	Glycine-extended gastrin promotes the growth of lung cancer.	Glycine	0-7	gastrin	Homo sapiens	17-24
14729624-2	2004	Although incompletely processed forms of gastrin such as glycine-extended gastrin and progastrin are also expressed in human lung cancers, the clinical significance of this expression has not been addressed.	Glycine	57-64	gastrin	Homo sapiens	41-48
14729624-2	2004	Although incompletely processed forms of gastrin such as glycine-extended gastrin and progastrin are also expressed in human lung cancers, the clinical significance of this expression has not been addressed.	Glycine	57-64	gastrin	Homo sapiens	74-81
14729624-4	2004	We found that transgenic overexpression of glycine-extended gastrin in FVB/N mice resulted in a significant increase in the prevalence and growth of bronchoalveolar carcinoma.	Glycine	43-50	gastrin	Homo sapiens	60-67
14729624-6	2004	Overexpression of glycine-extended gastrin by human lung cancers was associated with a significantly decreased survival.	Glycine	18-25	gastrin	Homo sapiens	35-42
14729624-7	2004	Taken together, these results suggest that glycine-extended gastrin may play a role in the growth and progression of some human lung cancers.	Glycine	43-50	gastrin	Homo sapiens	60-67
15338453-5	2004	A single nucleotide substitution of G to A at nucleotide position 3934 changed the coding sense of exon 21 of the SCN5A from glycine to serine (G1262S) in segment 2 of domain III (DIII-S2).	Glycine	125-132	sodium voltage-gated channel alpha subunit 5	Homo sapiens	114-119
15887520-4	2004	GSH synthetase catalyzes the reaction between amine residue of glycine and the cysteine carboxyl from gamma-glutamylcysteine dipeptide to form GSH.	Glycine	63-70	glutathione synthetase	Homo sapiens	0-14
14656520-0	2003	Pharmacokinetics of glycine-proline-glutamate, the N-terminal tripeptide of insulin-like growth factor-1, in rats.	Glycine	20-27	insulin-like growth factor 1	Rattus norvegicus	76-104
14615585-7	2003	We have now found that GLYT1, a glycine transporter of the neurotransmitter transporter gene family, functions as the organic osmolyte transporter that mediates the osmotically regulated accumulation of glycine and regulates cell volume in early embryos.	Glycine	32-39	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	23-28
14604673-1	2003	The thioredoxins are small ubiquitous redox proteins with the conserved redox catalytic sequence-Trp-Cys-Gly-Pro-Cys-Lys, where the Cys residues undergo reversible NADPH dependent reduction by selenocysteine containing flavoprotein thioredoxin reductases.	Glycine	105-108	thioredoxin	Homo sapiens	4-16
14604673-1	2003	The thioredoxins are small ubiquitous redox proteins with the conserved redox catalytic sequence-Trp-Cys-Gly-Pro-Cys-Lys, where the Cys residues undergo reversible NADPH dependent reduction by selenocysteine containing flavoprotein thioredoxin reductases.	Glycine	105-108	thioredoxin	Homo sapiens	4-15
14507877-5	2003	Cytochalasin D (an inhibitor of microfilament formation) and the peptide GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro), a fibronectin receptor antagonist, each inhibited this effect of fibronectin, whereas nocodazole (an inhibitor of microtubule polymerization) and the control peptide GRGESP (Gly-Arg-Gly-Glu-Ser-Pro) did not.	Glycine	81-84	fibronectin 1	Bos taurus	109-120
14507877-5	2003	Cytochalasin D (an inhibitor of microfilament formation) and the peptide GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro), a fibronectin receptor antagonist, each inhibited this effect of fibronectin, whereas nocodazole (an inhibitor of microtubule polymerization) and the control peptide GRGESP (Gly-Arg-Gly-Glu-Ser-Pro) did not.	Glycine	81-84	fibronectin 1	Bos taurus	172-183
14551753-5	2003	Coexpression of alpha(1)- and beta-subunits resulted in a significantly lower EC(50) and a reduced slope of the dose-response curve of glycine compared with expression of alpha(1)-subunits alone.	Glycine	135-142	adrenoceptor alpha 1D	Homo sapiens	16-34
12930794-6	2003	Nevertheless, GluRs lack a glycine residue at a homologous structural position as the gating hinge glycine in K+ channels.	Glycine	27-34	glutamyl-tRNA synthetase 2, mitochondrial	Homo sapiens	14-19
12930794-6	2003	Nevertheless, GluRs lack a glycine residue at a homologous structural position as the gating hinge glycine in K+ channels.	Glycine	99-106	glutamyl-tRNA synthetase 2, mitochondrial	Homo sapiens	14-19
12930794-7	2003	Moreover, simultaneous substitution of the only two glycines in M3 of GluR-A with alanines produced channels with gating properties indistinguishable from wild type.	Glycine	52-60	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	70-76
12740394-7	2003	Although MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue, like their rat counterpart, MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form.	Glycine	103-106	microtubule-associated protein 1 light chain 3 alpha	Rattus norvegicus	9-17
12689336-1	2003	Annexin A11 is one of the 12 vertebrate subfamilies in the annexin superfamily of calcium/phospholipid-binding proteins, distinguishable by long, non-homologous N-termini rich in proline, glycine and tyrosine residues.	Glycine	188-195	annexin A11	Mus musculus	0-11
14502435-1	2003	The pharmacological activation of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel mutated at glycine 551 (G551D-CFTR) was studied in the presence of the benzimidazolone derivative NS004 and compared to that of wild-type (wt) CFTR.	Glycine	125-132	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	38-89
14502435-1	2003	The pharmacological activation of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel mutated at glycine 551 (G551D-CFTR) was studied in the presence of the benzimidazolone derivative NS004 and compared to that of wild-type (wt) CFTR.	Glycine	125-132	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	91-95
12826625-5	2003	This protein exhibits significant sequence similarity with the yeast Pho89 protein, which is known to be a Na(+)/Pi co-transporter, although the PTB1 protein carries an additional Gln- and Gly-rich large hydrophilic region in the middle of its primary structure.	Glycine	189-192	Pho89p	Saccharomyces cerevisiae S288C	69-74
12717016-1	2003	The hinge residues (Val29 and Ile36) of the switch I region (also known as the effector loop) of the Ha-ras-p21 protein have been mutated to glycines to accelerate the conformational changes typical for the effector loop.	Glycine	141-149	H3 histone pseudogene 16	Homo sapiens	108-111
12574161-10	2003	PNUTS exhibited selective binding for poly(A) and poly(G) compared with poly(U) or poly(C) ribonucleotide homopolymers, with specificity being mediated by distinct regions within the domain rich in His and Gly and the domain containing the RGG motifs.	Glycine	206-209	protein phosphatase 1 regulatory subunit 10	Homo sapiens	0-5
12554738-2	2003	Here we analyze properties of human FEN1 having mutations at two conserved glycines (G66S and G242D) causing defects in nuclease activity.	Glycine	75-83	flap structure-specific endonuclease 1	Homo sapiens	36-40
12667057-9	2003	Sequence and structural analysis of the beta4Gal-T1 family with 37 known sequences reveals that in contrast to the unconserved long loop, which undergoes a much larger conformational change, the Trp loop including the glycines is highly conserved.	Glycine	218-226	beta-1,4-galactosyltransferase 1	Homo sapiens	40-51
12639933-4	2003	Binding of glomerulosa cells to fibronectin, but not to collagen I or poly-L-lysine, involved the integrin-binding sequence Arg-Gly-Asp (RGD).	Glycine	128-131	fibronectin 1	Rattus norvegicus	32-43
12673575-9	2003	Interestingly, as compared with the other joint allelic types, a significant excess of carrying both DRD3 variant allele (Gly) and MnSOD wild allele (Val) was found in the TD group (P&lt;0.05).	Glycine	122-125	dopamine receptor D3	Homo sapiens	101-105
12658435-4	2003	The anchoring protein gephyrin is involved in the postsynaptic accumulation of both glycine and GABA(A) receptors.	Glycine	84-91	gephyrin	Homo sapiens	22-30
12573254-2	2003	Both a chemically inhibited form of HPL as well as an inactive HPL mutant with a glycine residue substituted for its catalytic serine were found to be strong inactivators of HPL activity.	Glycine	81-88	galectin 1	Homo sapiens	63-66
12573254-2	2003	Both a chemically inhibited form of HPL as well as an inactive HPL mutant with a glycine residue substituted for its catalytic serine were found to be strong inactivators of HPL activity.	Glycine	81-88	galectin 1	Homo sapiens	63-66
12586454-3	2003	The aim of this study was to evaluate the influence of the glycine binding site of the NMDA receptor on the behavioral effects of alcohol by investigating mice with an 80% reduced affinity of the NMDA R1 subunit for glycine (Grin1(D481N)).	Glycine	59-66	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	225-230
12586454-3	2003	The aim of this study was to evaluate the influence of the glycine binding site of the NMDA receptor on the behavioral effects of alcohol by investigating mice with an 80% reduced affinity of the NMDA R1 subunit for glycine (Grin1(D481N)).	Glycine	216-223	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	196-203
12574460-4	2003	The recombinant AptNR1/NR2B receptors produced robust currents after stimulation with glutamate or NMDA in the presence of glycine.	Glycine	123-130	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	23-27
12507496-3	2003	The C-terminal Phe(117) of proGATE-16 and the C-terminal Leu(117) of proGABARAP are post-translationally cleaved to expose an essential Gly(116) within GATE-16 and GABARAP, with the products designated GATE-16-I and GABARAP-I, respectively.	Glycine	136-139	GABA type A receptor-associated protein	Homo sapiens	72-79
12507496-3	2003	The C-terminal Phe(117) of proGATE-16 and the C-terminal Leu(117) of proGABARAP are post-translationally cleaved to expose an essential Gly(116) within GATE-16 and GABARAP, with the products designated GATE-16-I and GABARAP-I, respectively.	Glycine	136-139	GABA type A receptor-associated protein	Homo sapiens	164-171
12507496-4	2003	The Gly(116) within GATE-16 and GABARAP are essential for further formation of the intermediates between them and Apg7p(C572S) and Apg3p(C264S).	Glycine	4-7	GABA type A receptor-associated protein	Homo sapiens	32-39
12414796-1	2003	In human glutathione transferase P1-1 (hGSTP1-1) position 146 is occupied by a glycine residue, which is located in a bend of a long loop that together with the alpha6-helix forms a substructure (GST motif II) maintained in all soluble GSTs.	Glycine	79-86	glutathione S-transferase pi 1	Homo sapiens	39-47
12426378-4	2002	We analyzed the degradation signal (degron) of c-MOS in Xenopus oocytes, found it to be a portable degron, and demonstrated that, contrary to the model above, the N-terminal Pro residue of c-MOS is entirely dispensable for its degradation if Ser-2 (encoded Ser-3) of c-MOS is replaced by a small non-phosphorylatable residue such as Gly.	Glycine	333-336	MOS proto-oncogene, serine/threonine kinase L homeolog	Xenopus laevis	47-52
12523648-1	2002	Fibrillarin is a conserved nucleolar SnoRNP with a diverse N-terminal glycine- and arginine-rich (GAR) domain in most eukaryotes.	Glycine	70-77	fibrillarin	Mus musculus	0-11
12122010-4	2002	The putative WCSP1 protein contains a three-domain structure consisting of an N-terminal cold shock domain with two internal conserved consensus RNA binding domains and an internal glycine-rich region, which is interspersed with three C-terminal CX(2)CX(4)HX(4)C (CCHC) zinc fingers.	Glycine	181-188	glycine-rich protein 2	Triticum aestivum	13-18
12213887-10	2002	Thus, individuals with the common IRS-2 Gly/Gly genotype may be at increased risk of developing type 2 diabetes.	Glycine	40-43	insulin receptor substrate 2	Homo sapiens	34-39
12213887-10	2002	Thus, individuals with the common IRS-2 Gly/Gly genotype may be at increased risk of developing type 2 diabetes.	Glycine	44-47	insulin receptor substrate 2	Homo sapiens	34-39
14582365-1	2003	We reported a 69-year-old woman with multiple system atrophy (MSA), who had a heteroallelic missense mutation (G1874A, Gly-->Glu) in the exon 11 of the ceruloplasmin (Cp) gene.	Glycine	119-122	ceruloplasmin	Homo sapiens	152-165
12697759-0	2003	Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling.	Glycine	54-61	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	24-53
12697759-1	2003	The N-methyl-d-aspartate (NMDA) receptor is a ligand-gated ion channel that requires both glutamate and glycine for efficient activation.	Glycine	104-111	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	4-40
12697759-2	2003	Here, a strategy combining cysteine scanning mutagenesis and affinity labeling was used to investigate the glycine binding site located on the NR1 subunit.	Glycine	107-114	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	143-146
21282399-11	2011	As we previously showed for alpha1 homomeric receptors, in alpha2 glycine channels, maximum P(open) is achieved when fewer than all five of the putative binding sites in the pentamer are occupied by glycine.	Glycine	66-73	adrenoceptor alpha 1D	Homo sapiens	28-34
21283809-12	2011	Furthermore, a glycine and three cysteine residues were absolutely conserved in all DIA1-family proteins, indicating a critical role in protein structure and/or function.	Glycine	15-22	divergent protein kinase domain 2A	Homo sapiens	84-88
12727219-6	2003	Functional expression in either mammalian cells or Xenopus laevis oocytes demonstrates that rat PAT2 mediates pH-dependent, Na(+)-independent uptake of glycine, proline, and alpha(methyl)aminoisobutyric acid (MeAIB).	Glycine	152-159	solute carrier family 36 member 2	Rattus norvegicus	96-100
12727219-7	2003	In conclusion PAT2 has a limited tissue distribution, higher affinity (Michaelis-Menten constant for glycine uptake between 0.49 and 0.69mM), and distinct substrate specificity compared to PAT1.	Glycine	101-108	solute carrier family 36 member 2	Rattus norvegicus	14-18
12223091-3	2002	Methyl-beta-cyclodextrin and some osmolytes, such as glycerol, sucrose, proline, glycine, and heparin, could effectively prevent the aggregation, implying an artificial chaperone role of those substances during fatty acid synthase unfolding.	Glycine	81-88	fatty acid synthase	Gallus gallus	211-230
20691150-1	2011	The H(+)-coupled amino acid transporter PAT2 (SLC36A2) transports the amino acids proline, glycine, alanine and hydroxyproline.	Glycine	91-98	solute carrier family 36 member 2	Homo sapiens	40-44
12123749-3	2002	The inhibition constants of the agonist glycine showed opposite temperature dependence on alpha(1) GlyRs, corresponding to endothermic binding driven by large entropic increases.	Glycine	40-47	glycine receptor alpha 1	Homo sapiens	90-104
12839295-6	2003	The boy was a compound heterozygote for four molecular defects in the LPL gene, two of which have not been reported before (CGT764 CTT/Arg170 --&gt; Leu; GGA1482 --&gt; GGT/Gly409 --&gt; Gly).	Glycine	173-176	lipoprotein lipase	Homo sapiens	70-73
20691150-1	2011	The H(+)-coupled amino acid transporter PAT2 (SLC36A2) transports the amino acids proline, glycine, alanine and hydroxyproline.	Glycine	91-98	solute carrier family 36 member 2	Homo sapiens	46-53
12686604-6	2003	Desmin mutants, in which in vitro phosphorylation sites by Aurora-B and/or Rho-kinase are changed to Ala or Gly, cause dramatic defects in filament separation between daughter cells in cytokinesis.	Glycine	108-111	desmin	Homo sapiens	0-6
20564011-3	2011	Although this is consistent with dimethylated NKB-Gly-Lys-Arg, further characterization (immunological and mass spectrometric fragment analysis) suggested a novel posttranslational modification containing phosphocholine (PC) with some evidence for glycerol and a coordinated alkene.	Glycine	50-53	tachykinin precursor 3	Homo sapiens	46-49
12673575-13	2003	A combination of DRD3 variant allele (Gly) and MnSOD wild allele (Val) may increase the susceptibility to the development of TD.	Glycine	38-41	dopamine receptor D3	Homo sapiens	17-21
12514178-1	2003	Cytoplasmic serine hydroxymethyltransferase (cSHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	192-199	serine hydroxymethyltransferase 1	Homo sapiens	0-43
12514178-1	2003	Cytoplasmic serine hydroxymethyltransferase (cSHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	192-199	serine hydroxymethyltransferase 1	Homo sapiens	45-50
12065292-3	2002	The transport of [14C]glycylsarcosine (Gly-Sar), a typical substrate for PEPT1 by in situ intestinal loop and everted intestine, was greater in the dark phase than the light phase.	Glycine	39-42	solute carrier family 15 member 1	Rattus norvegicus	73-78
20939034-4	2011	Here, we designed a novel scaffold where fibronectin-derived Gly Arg-Gly-Asp-Ser (GRGDS) and Pro-His-Ser-Arg-Asn (PHSRN) peptides were simultaneously conjugated with poly(Pro-Hyp-Gly).	Glycine	61-64	fibronectin 1	Bos taurus	41-52
12062911-4	2002	Four published studies have reported an association between a serine (ser) to glycine (gly) polymorphism in exon 1 of the dopamine D3 receptor gene (DRD3) and TD; three failed to replicate this finding and one found an insignificant trend.	Glycine	78-85	dopamine receptor D3	Homo sapiens	149-153
12062911-4	2002	Four published studies have reported an association between a serine (ser) to glycine (gly) polymorphism in exon 1 of the dopamine D3 receptor gene (DRD3) and TD; three failed to replicate this finding and one found an insignificant trend.	Glycine	78-81	dopamine receptor D3	Homo sapiens	149-153
12062911-7	2002	TD was significantly associated with DRD3 gly allele carrier status (x(2)=4.46, df 1, p =.04) and with DRD3 genotype (x(2)=6.62, df 2, p =.04) over and above the effect of group.	Glycine	42-45	dopamine receptor D3	Homo sapiens	37-41
12646235-5	2003	However, Spred-3 does not possess a functional c-kit binding domain (KBD), since the critical amino acid Arg residue in this region was replaced with Gly in Spred-3.	Glycine	150-153	sprouty related EVH1 domain containing 3	Homo sapiens	157-164
20939034-4	2011	Here, we designed a novel scaffold where fibronectin-derived Gly Arg-Gly-Asp-Ser (GRGDS) and Pro-His-Ser-Arg-Asn (PHSRN) peptides were simultaneously conjugated with poly(Pro-Hyp-Gly).	Glycine	69-72	fibronectin 1	Bos taurus	41-52
12062911-11	2002	The Mantel-Haenszel pooled odds ratio for DRD3 gly allele carrier status increasing susceptibility to TD was 1.33 (95% CI 1.04-1.70, p =.02); the cumulative pooled estimate showed an odds ratio of 1.52 (95% CI 1.08-1.68, p &lt;.0001).	Glycine	47-50	dopamine receptor D3	Homo sapiens	42-46
12628383-3	2003	Approximately 80% of the amino acids in BMCPA were composed of Ser, Ala, Gly, Pro, Val and Tyr.	Glycine	73-76	cuticular protein glycine-rich 4	Bombyx mori	40-45
21950764-11	2011	It was also supported by our observation of a family from Southeast Asia, in which a child homozygous for an AHSP mutant (Val56&gt;Gly) displayed, in his first year of life, a moderate thalassemia syndrome.	Glycine	131-134	alpha hemoglobin stabilizing protein	Homo sapiens	109-113
12612034-1	2003	Previously we have shown that strychnine-sensitive glycine-gated chloride channels (GlyRs) are functionally expressed by CA1 pyramidal cells and GABAergic interneurons in mature rat hippocampal slices.	Glycine	51-58	carbonic anhydrase 1	Rattus norvegicus	121-124
12612034-2	2003	We now report that glycine application to dentate granule cells and hilar interneurons recorded in acute slices from adolescent rats elicits a strychnine-sensitive current similar to glycine-mediated currents recorded in area CA1, indicating that GlyRs are also present on neurons in the dentate gyrus.	Glycine	19-26	carbonic anhydrase 1	Rattus norvegicus	226-229
21175814-7	2011	Cytokine levels (tumor necrosis factor-alpha, interleukin-8) and hepatocellular injury (aspartate aminotransferase and alanine aminotransferase) were significantly reduced by glycine administration.	Glycine	175-182	tumor necrosis factor	Oryctolagus cuniculus	0-44
12661758-10	2003	We found that five of them significantly enhanced the inward current induced by glycine with the following order of potency: Rb1 &gt; Rb2 &gt; Rg2 &gt; or = Rc &gt; Rf &gt; Rg1 &gt; Re.	Glycine	80-87	retinoblastoma-like 2 L homeolog	Xenopus laevis	134-137
12009900-3	2002	In this study, analogues of Ac-Arg(6)-cyclo(S-S)(Cys(7)-Met(8)-Leu(9)-Gly(10)-Arg(11)-Val(12)-Tyr(13)-Arg(14)-Pro(15)-Cys(16))-NH(2), a high affinity but nonselective agonist at hMCH-1R and hMCH-2R, were prepared and tested in binding and functional assays on cells expressing these receptors.	Glycine	70-73	melanin concentrating hormone receptor 1	Homo sapiens	178-185
12009900-3	2002	In this study, analogues of Ac-Arg(6)-cyclo(S-S)(Cys(7)-Met(8)-Leu(9)-Gly(10)-Arg(11)-Val(12)-Tyr(13)-Arg(14)-Pro(15)-Cys(16))-NH(2), a high affinity but nonselective agonist at hMCH-1R and hMCH-2R, were prepared and tested in binding and functional assays on cells expressing these receptors.	Glycine	70-73	melanin concentrating hormone receptor 2	Homo sapiens	190-197
20238170-2	2011	In this study, we used PCR-SSCP to analyse the ovine KAP6 family which encodes glycine and tyrosine-rich KAPs.	Glycine	79-86	keratin-associated protein 6-1	Ovis aries	53-57
11959905-8	2002	This glycine in P-loop A of AtHKT1 and HKT1 can be modeled as the first glycine of the K(+) channel selectivity filter GYG motif.	Glycine	5-12	high-affinity K+ transporter 1	Arabidopsis thaliana	28-34
12473676-7	2003	CN1 was identified as a homodimeric dipeptidase with a narrow substrate specificity for Xaa-His dipeptides including those with Xaa = beta Ala (carnosine, K(m) 1.2 mM), N-methyl beta Ala, Ala, Gly, and gamma-aminobutyric acid (homocarnosine, K(m) 200 microM), an isoelectric point of pH 4.5, and maximal activity at pH 8.5.	Glycine	193-196	carnosine dipeptidase 1	Homo sapiens	0-3
11959905-8	2002	This glycine in P-loop A of AtHKT1 and HKT1 can be modeled as the first glycine of the K(+) channel selectivity filter GYG motif.	Glycine	72-79	high-affinity K+ transporter 1	Arabidopsis thaliana	28-34
21949857-5	2011	The number of Fos-positive orexin neurons markedly decreased after intraperitoneal administration of glycine to mice.	Glycine	101-108	FBJ osteosarcoma oncogene	Mus musculus	14-17
21858052-4	2011	Some of these GABA-, Gly-, 5-HT-, or DBH-LI axon terminals were observed to make principally symmetric synapses with NK1 receptor-LI neuronal cell bodies and dendritic processes in laminae I, II and III of the MDH.	Glycine	21-24	tachykinin receptor 1	Rattus norvegicus	117-129
11983234-4	2002	Using a lambda phage based C-terminal random peptide library, and an intracellular expression library based on truncated tau, we show that this antibody has an absolute requirement for a glycine at position -3 with respect to the C terminus.	Glycine	187-194	microtubule associated protein tau	Homo sapiens	121-124
12574119-0	2003	Galpha(s) is palmitoylated at the N-terminal glycine.	Glycine	45-52	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	0-6
12574119-9	2003	Thereby, Gly(2)-palmitoylation of Galpha(s) relieves cellular stimulation at the level of adenylyl cyclase whereas it renders the inhibitory modulation via Galpha(i) more difficult.	Glycine	9-12	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	34-40
12574119-9	2003	Thereby, Gly(2)-palmitoylation of Galpha(s) relieves cellular stimulation at the level of adenylyl cyclase whereas it renders the inhibitory modulation via Galpha(i) more difficult.	Glycine	9-12	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	156-162
12586454-0	2003	Involvement of NMDA receptors in alcohol-mediated behavior: mice with reduced affinity of the NMDA R1 glycine binding site display an attenuated sensitivity to ethanol.	Glycine	102-109	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	94-101
21901142-6	2011	We found that alanine 52 in extracellular loop 2, glycine 254 in transmembrane (TM) region 2 and intracellular lysine 385 determine the positive modulation of alpha(1) GlyRs by NA-Gly.	Glycine	50-57	glycine receptor alpha 1	Homo sapiens	159-173
11883939-7	2002	The Ca(2+)-dependent fluorescence change of ALG-2 in the presence of the hydrophobicity fluorescent probe 2-p-toluidinylnaphthalene-6-sulfonate (TNS) was inhibited by mixing with GST-AnxN, suggesting that the Pro/Gly/Tyr/Ala-rich hydrophobic region in AnxN masked the Ca(2+)-dependently exposed hydrophobic surface of ALG-2.	Glycine	213-216	glutathione S-transferase kappa 1	Homo sapiens	179-182
20865248-1	2011	RATIONALE: Enhancement of N-methyl-D: -aspartate receptor (NMDAR) activity through its glycine modulatory site (GMS) is a novel therapeutic approach in schizophrenia.	Glycine	87-94	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	26-57
11840480-7	2002	The majority (60-75%) of terminals presynaptic to Renshaw cell gephyrin patches contained immunocytochemical markers for GABA as well as glycine, but a proportion contained markers only for glycine.	Glycine	137-144	gephyrin	Homo sapiens	63-71
20865248-1	2011	RATIONALE: Enhancement of N-methyl-D: -aspartate receptor (NMDAR) activity through its glycine modulatory site (GMS) is a novel therapeutic approach in schizophrenia.	Glycine	87-94	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	59-64
21157735-5	2010	The genetic analysis identified a new mutation for this disease in codon 296 of exon 6 in the Notch-3 gene that produces a change of amino acid, from glycine to cysteine in protein (p.G296C).	Glycine	150-157	notch receptor 3	Homo sapiens	94-101
11867756-1	2002	We generated a set of cysteine-to-glycine mutations and screened them to identify a temperature-sensitive allele of the human cytomegalovirus UL122 gene, which encodes the immediate-early 2 transcriptional activating protein.	Glycine	34-41	regulatory protein IE2	Human betaherpesvirus 5	142-147
20727916-1	2010	Progastrin is processed to a number of peptides including glycine-extended gastrin, amidated gastrin and the C-terminal flanking peptide (CTFP).	Glycine	58-65	gastrin	Homo sapiens	3-10
11871737-9	2002	RESULTS: Perfusion with 20% glycine increased mucosal protein content (p &lt; .05), increased mucosal DNA content (p &lt; .05), reduced intestinal myeloperoxidase activity (p &lt; .05), and maintained mucosal glutaminase activity.	Glycine	28-35	myeloperoxidase	Rattus norvegicus	147-162
20727916-1	2010	Progastrin is processed to a number of peptides including glycine-extended gastrin, amidated gastrin and the C-terminal flanking peptide (CTFP).	Glycine	58-65	gastrin	Homo sapiens	75-82
20818663-6	2010	Three novel COL4A1 missense substitutions are described, which affect highly conserved glycine residues within the collagenous domain of the protein.	Glycine	87-94	collagen type IV alpha 1 chain	Homo sapiens	12-18
19864106-6	2010	Recently, glycine has been reported to have anti-inflammatory properties which reduce TNF-alpha and IL-6 levels and increase adiponectin in 3T3-L1 adipocytes and in fat tissue of obese mice.	Glycine	10-17	adiponectin, C1Q and collagen domain containing	Mus musculus	125-136
11891256-8	2002	AtCPK2 was myristoylated in a cell-free extract and myristoylation was prevented by converting the glycine at the proposed site of myristate attachment to alanine (G2A).	Glycine	99-106	calmodulin-domain protein kinase cdpk 	Arabidopsis thaliana	0-6
19864106-10	2010	Interestingly, glycine treatment also suppressed the expression of UCP-2, TNF-alpha and IL-6 in lean mice, and increased adiponectin and insulin serum levels.	Glycine	15-22	adiponectin, C1Q and collagen domain containing	Mus musculus	121-132
20518783-9	2010	Sequence analyses of the COL3A1 gene demonstrated heterozygous point mutations leading to glycine substitution in only nine patients (45%), while heterozygous splice-site mutations at the junction of the triple-helical exons were observed in the remaining 11 patients (55%).	Glycine	90-97	collagen type III alpha 1 chain	Homo sapiens	25-31
11739386-3	2002	Its glycine- and serine-rich NH(2)-terminal domain may fold to give structural motifs similar to the glycine loops described in epidermal cytokeratins and loricrin and proposed to display adhesive properties.	Glycine	4-11	loricrin	Mus musculus	155-163
11739386-3	2002	Its glycine- and serine-rich NH(2)-terminal domain may fold to give structural motifs similar to the glycine loops described in epidermal cytokeratins and loricrin and proposed to display adhesive properties.	Glycine	101-108	loricrin	Mus musculus	155-163
11739386-8	2002	The results confirmed that corneodesmosin presents homophilic interactions and indicated that its NH(2)-terminal glycine loop domain is sufficient but not strictly necessary to promote binding.	Glycine	113-120	corneodesmosin	Mus musculus	27-41
11739386-9	2002	Altogether, these results provide the first experimental evidence for the adhesive properties of corneodesmosin and for the involvement of its glycine loop domain in adhesion.	Glycine	143-150	corneodesmosin	Mus musculus	97-111
20880398-9	2010	CONCLUSION AND IMPLICATIONS Our results suggest that whereas Gly-Gly amid bond bioisosteres are widely accepted by the hPAT1 carrier, dipeptides in general are not; and therefore, Gly-Sar might structurally define the size limit of dipeptide transport via SLC36A1.	Glycine	61-64	solute carrier family 36 member 1	Homo sapiens	119-124
20880398-9	2010	CONCLUSION AND IMPLICATIONS Our results suggest that whereas Gly-Gly amid bond bioisosteres are widely accepted by the hPAT1 carrier, dipeptides in general are not; and therefore, Gly-Sar might structurally define the size limit of dipeptide transport via SLC36A1.	Glycine	61-64	solute carrier family 36 member 1	Homo sapiens	256-263
20880398-9	2010	CONCLUSION AND IMPLICATIONS Our results suggest that whereas Gly-Gly amid bond bioisosteres are widely accepted by the hPAT1 carrier, dipeptides in general are not; and therefore, Gly-Sar might structurally define the size limit of dipeptide transport via SLC36A1.	Glycine	65-68	solute carrier family 36 member 1	Homo sapiens	119-124
11861317-7	2002	Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors.	Glycine	46-53	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	74-77
20880398-9	2010	CONCLUSION AND IMPLICATIONS Our results suggest that whereas Gly-Gly amid bond bioisosteres are widely accepted by the hPAT1 carrier, dipeptides in general are not; and therefore, Gly-Sar might structurally define the size limit of dipeptide transport via SLC36A1.	Glycine	65-68	solute carrier family 36 member 1	Homo sapiens	119-124
11861317-7	2002	Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors.	Glycine	46-53	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	87-90
11861317-7	2002	Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors.	Glycine	46-53	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	91-95
20635087-6	2010	Also supporting a key role for the FATC domain in the structure/function of Tra1, addition of a C-terminal glycine residue resulted in decreased association with Spt7 and Esa1, and loss of cellular viability.	Glycine	107-114	histone acetyltransferase TRA1	Saccharomyces cerevisiae S288C	76-80
20850334-1	2010	Among the three zinc finger-containing glycine-rich RNA-binding proteins, named AtRZ-1a, AtRZ-1b, and AtRZ-1c, in the Arabidopsis thaliana genome, AtRZ-1a has previously been shown to enhance cold and freezing tolerance in Arabidopsis.	Glycine	39-46	RNA-binding (RRM/RBD/RNP motifs) family protein with retrovirus zinc finger-like domain-containing protein	Arabidopsis thaliana	80-87
11934254-9	2002	IGFBP-1 stimulation of EVT cell migration appears to occur by binding its Arg-Gly-Asp (RGD) domain to alpha5beta1 integrin, leading to phosphorylation of focal adhesion kinase (FAK) and MAPK (ERK-1 and ERK-2).	Glycine	78-81	insulin like growth factor binding protein 1	Homo sapiens	0-7
12207142-6	2002	We conclude that PDYN gene polymorphism alone does not alter the risk for schizophrenia but, by an epistatic interaction with the Gly allele of DRD3 gene, may contribute to the susceptibility to this disorder.	Glycine	130-133	prodynorphin	Homo sapiens	17-21
20850334-1	2010	Among the three zinc finger-containing glycine-rich RNA-binding proteins, named AtRZ-1a, AtRZ-1b, and AtRZ-1c, in the Arabidopsis thaliana genome, AtRZ-1a has previously been shown to enhance cold and freezing tolerance in Arabidopsis.	Glycine	39-46	RNA-binding (RRM/RBD/RNP motifs) family protein with retrovirus zinc finger-like domain-containing protein	Arabidopsis thaliana	89-96
12207142-6	2002	We conclude that PDYN gene polymorphism alone does not alter the risk for schizophrenia but, by an epistatic interaction with the Gly allele of DRD3 gene, may contribute to the susceptibility to this disorder.	Glycine	130-133	dopamine receptor D3	Homo sapiens	144-148
20850334-1	2010	Among the three zinc finger-containing glycine-rich RNA-binding proteins, named AtRZ-1a, AtRZ-1b, and AtRZ-1c, in the Arabidopsis thaliana genome, AtRZ-1a has previously been shown to enhance cold and freezing tolerance in Arabidopsis.	Glycine	39-46	RNA-binding (RRM/RBD/RNP motifs) family protein with retrovirus zinc finger-like domain-containing protein	Arabidopsis thaliana	147-154
20685300-1	2010	Missense PTEN mutations of the active site residues Asp-92, Cys-124 and Gly-129 contribute to Cowden syndrome.	Glycine	72-75	phosphatase and tensin homolog	Homo sapiens	9-13
11572870-3	2001	The repetitive domain of hornerin was found to be rich in glycine, serine, and glutamine.	Glycine	58-65	hornerin	Mus musculus	25-33
11741582-3	2001	Here we have tested the functional importance of Gly(113), a highly conserved residue of human sphingosine kinase 1 (hSK), by site-directed mutagenesis.	Glycine	49-52	sphingosine kinase 1	Homo sapiens	95-115
20566661-4	2010	Like other K(+) channels, K2P channels are thought to have two primary conserved gating mechanisms: an inactivation (or C-type) gate at the selectivity filter close to the extracellular side of the channel and an activation gate at the intracellular entrance to the channel involving key, identified, hinge glycine residues.	Glycine	307-314	keratin 76	Homo sapiens	26-29
11723742-4	2001	The cell-binding domain obtained from fibronectin included the Arg-Gly-Asp (RGD) sequence.	Glycine	67-70	fibronectin 1	Mus musculus	38-49
11563854-5	2001	Stimulation of HAECs with gly-ox-HDL elicited a marked increase in caspase 3 activity and the expressions of active caspase 3 and caspase 9, whereas concomitant treatment with a caspase 3 inhibitor significantly blocked gly-ox-HDL-induced apoptosis of HAECs.	Glycine	26-29	caspase 9	Homo sapiens	130-139
20176108-7	2010	Another interesting mutant we have characterized is F26A IKK-2 (F26 is an aromatic residue located at the very tip of the Gly-rich loop).	Glycine	122-125	inhibitor of nuclear factor kappa B kinase subunit beta	Homo sapiens	57-62
20506101-5	2010	In brain stem and spinal cord, Cre expressing cells were identified as glycinergic interneurons by staining with GlyT2- and glycine-immunoreactive antibodies; here, &gt;80% of the glycine-immunoreactive cells expressed the Cre reporter protein.	Glycine	71-78	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	113-118
11535048-5	2001	The maximum at 281 nm in the absorption spectrum of glycine-extended gastrin(17) at pH 4.0 increased (2.07 +/- 0.30)-fold in the presence of &gt; or =2 equiv of ferric ions.	Glycine	52-59	gastrin	Homo sapiens	69-76
11535048-6	2001	Titration of glycine-extended gastrin(17) with ferric ions under stoichiometric conditions indicated that the stoichiometry of binding was 2.00 +/- 0.28 mol of Fe(3+)/mol of peptide.	Glycine	13-20	gastrin	Homo sapiens	30-37
20206270-1	2010	The scaffolding protein gephyrin is essential for the clustering of glycine and GABA(A) receptors (GABA(A)Rs) at inhibitory synapses.	Glycine	68-75	gephyrin	Homo sapiens	24-32
11522328-3	2001	PREGS resulted in a parallel shift of the response curve of glycine for alpha(1) GlyRs.	Glycine	60-67	glycine receptor alpha 1	Homo sapiens	72-86
12559755-2	2003	This conclusion was based on the observations that Npap60/Nup50 localizes at the NPC by immunofluorescence and electron microscopy and also contains FG (Phe-Gly) repeats, a motif commonly found in nucleoporins but not in proteins located elsewhere.	Glycine	157-160	nucleoporin 50	Homo sapiens	51-57
12559755-2	2003	This conclusion was based on the observations that Npap60/Nup50 localizes at the NPC by immunofluorescence and electron microscopy and also contains FG (Phe-Gly) repeats, a motif commonly found in nucleoporins but not in proteins located elsewhere.	Glycine	157-160	nucleoporin 50	Homo sapiens	58-63
20360009-10	2010	A series of N-terminal deletions identified a 12-amino acid region, Gly(206)-Pro(217), as being required for the rapid recycling of KCa2.3.	Glycine	68-71	potassium calcium-activated channel subfamily N member 3	Homo sapiens	132-138
15044825-5	2003	Serine hydroxymethyltransferase (SHMT) is a member of this alpha-class; it reversibly catalyses the conversion of serine into glycine while the hydroxymethyl group is transferred to 5,6,7,8-tetrahydrofolate.	Glycine	126-133	serine hydroxymethyltransferase 1	Homo sapiens	0-31
15044825-5	2003	Serine hydroxymethyltransferase (SHMT) is a member of this alpha-class; it reversibly catalyses the conversion of serine into glycine while the hydroxymethyl group is transferred to 5,6,7,8-tetrahydrofolate.	Glycine	126-133	serine hydroxymethyltransferase 1	Homo sapiens	33-37
11423543-5	2001	By using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, we show that in addition to 14:0 (myristate), 14:1 and 14:2 fatty acids can be attached to the N-terminal glycine of the Src family kinase Fyn when the growth media are supplemented with these dietary fatty acids.	Glycine	193-200	FYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	208-211
11423543-5	2001	By using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, we show that in addition to 14:0 (myristate), 14:1 and 14:2 fatty acids can be attached to the N-terminal glycine of the Src family kinase Fyn when the growth media are supplemented with these dietary fatty acids.	Glycine	193-200	FYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	226-229
20333677-11	2010	Bcl-2/Bax ratio was significantly higher with the antagonist, suggested that the glycine site-specific NMDA receptor antagonist protecting RGC death might through inhibition of apoptotic signaling.	Glycine	81-88	BCL2 associated X, apoptosis regulator	Rattus norvegicus	6-9
11466341-2	2001	Selection begins with the V(H) third complementarity-determining region (CDR3) at the pre-B cell stage, in which most V(H)12 pre-B cells are selectively eliminated, enriching for those with V(H)CDR3s of 10 aa and a fourth position Gly (designated 10/G4).	Glycine	231-234	cerebellar degeneration-related 3	Mus musculus	73-77
11508863-3	2001	The early systemic increase of the proinflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL) -6 as well as the secretion of the antiinflammatory cytokine IL-10 was reduced by glycine.	Glycine	204-211	interleukin 10	Rattus norvegicus	183-188
11508863-4	2001	Tissue cytokine mRNA expression (TNF-alpha, IL-1beta, IL-10) was decreased in the lung and the liver but not in the mesenteric lymph node or ileum, in the glycine-fed group.	Glycine	155-162	interleukin 10	Rattus norvegicus	54-59
12746734-2	2003	Accumulating evidence suggests the existence of a genetic disposition to TD and other extra pyramidal symptoms (EPS) most strongly linked to a ser/gly polymorphism in position 9 of the D3 dopamine receptor gene (DRD3).	Glycine	127-130	dopamine receptor D3	Homo sapiens	185-205
12746734-2	2003	Accumulating evidence suggests the existence of a genetic disposition to TD and other extra pyramidal symptoms (EPS) most strongly linked to a ser/gly polymorphism in position 9 of the D3 dopamine receptor gene (DRD3).	Glycine	127-130	dopamine receptor D3	Homo sapiens	212-216
20486847-10	2010	CONCLUSION: The persistence of oxidative stress, inflammatory reaction, and tubular necrosis, as well as exacerbation of p53-mediated tubular apoptosis, led to a more severe renal impairment in Gly-AKI rats treated with silymarin.	Glycine	194-197	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	121-124
12471605-1	2003	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to form glycine and monocarbonic groups, essential in several biosynthetic pathways.	Glycine	91-98	serine hydroxymethyltransferase 1	Homo sapiens	0-31
12471605-1	2003	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to form glycine and monocarbonic groups, essential in several biosynthetic pathways.	Glycine	91-98	serine hydroxymethyltransferase 1	Homo sapiens	33-37
11444980-1	2001	Guinea pig liver transglutaminase (TGase) reacts with 0.1 mM N-Cbz-L-Glu(gamma-p-nitrophenyl ester)Gly (5, prepared herein, K(M) = 0.02 mM) to undergo rapid acylation that can be followed spectrophotometrically at 400 nm (pH 7.0, 25 degrees C).	Glycine	99-102	protein-glutamine gamma-glutamyltransferase 2	Cavia porcellus	17-33
11444980-1	2001	Guinea pig liver transglutaminase (TGase) reacts with 0.1 mM N-Cbz-L-Glu(gamma-p-nitrophenyl ester)Gly (5, prepared herein, K(M) = 0.02 mM) to undergo rapid acylation that can be followed spectrophotometrically at 400 nm (pH 7.0, 25 degrees C).	Glycine	99-102	protein-glutamine gamma-glutamyltransferase 2	Cavia porcellus	35-40
20445432-7	2010	Genetic analysis revealed the substitution of valine for glycine on the human skeletal muscle sodium channel (SCN4A) gene.	Glycine	57-64	sodium voltage-gated channel alpha subunit 4	Homo sapiens	110-115
11408272-5	2001	Similarly, apical uptake of [(14)C]Gly-Sar decreased in cells treated with EGF, with an ED(50) value of 0.36 +/- 0.06 ng/ml (n = 6) EGF and a maximal inhibition of 80 +/- 0.02% (n = 6).	Glycine	35-38	epidermal growth factor	Homo sapiens	75-78
11408272-5	2001	Similarly, apical uptake of [(14)C]Gly-Sar decreased in cells treated with EGF, with an ED(50) value of 0.36 +/- 0.06 ng/ml (n = 6) EGF and a maximal inhibition of 80 +/- 0.02% (n = 6).	Glycine	35-38	epidermal growth factor	Homo sapiens	132-135
11408272-10	2001	We conclude that EGF treatment decreases Gly-Sar transport in Caco-2 cells by decreasing the number of peptide transporter molecules in the apical membrane.	Glycine	41-44	epidermal growth factor	Homo sapiens	17-20
12393916-5	2002	We have shown that Gly(82) of hSK1 is involved in ATP binding since mutation of this residue to alanine resulted in an enzyme with an approximately 45-fold higher K(m)((ATP)).	Glycine	19-22	sphingosine kinase 1	Homo sapiens	30-34
12244096-2	2002	The SMN protein is important in small nuclear ribonucleoprotein (snRNP) assembly and interacts with snRNP proteins via arginine/glycine-rich domains.	Glycine	128-135	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated	Homo sapiens	100-105
12512837-1	2002	The c-kit receptor tyrosine kinase (KIT) is constitutively activated by 2 types of naturally occurring mutations, the Val559--&gt;Gly (G559) mutation in the juxtamembrane domain and the Asp814--&gt;Val (V814) mutation in the catalytic domain.	Glycine	130-133	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	4-9
20096465-10	2010	Glycine serum levels were negatively associated with intensity of negative symptoms assessed by the PANSS negative subscale and the SANS total scores in the patients.	Glycine	0-7	USH1 protein network component sans	Homo sapiens	132-136
12512837-1	2002	The c-kit receptor tyrosine kinase (KIT) is constitutively activated by 2 types of naturally occurring mutations, the Val559--&gt;Gly (G559) mutation in the juxtamembrane domain and the Asp814--&gt;Val (V814) mutation in the catalytic domain.	Glycine	130-133	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	36-39
20332107-7	2010	By mutating both glycine residues to phenylalanine or glutamic acid, we were able to modulate the dimerization of AdipoR1, implicating a role for the GxxxG motif in AdipoR1 dimerization.	Glycine	17-24	adiponectin receptor 1	Homo sapiens	114-121
12433591-7	2002	Rhynchophylline and isorhynchophylline (30 microM) significantly reduced the maximal current responses evoked by NMDA and glycine (a co-agonist of NMDA receptor), but had no effect on the EC(50) values and Hill coefficients of NMDA and glycine for inducing currents.	Glycine	122-129	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	147-160
12376561-6	2002	The actions of IGFBP-3 and -5 on cell attachment to ECM were lost in the presence of a soluble Arg-Gly-Asp (RGD)-containing fibronectin fragment.	Glycine	99-102	insulin like growth factor binding protein 3	Homo sapiens	15-29
11445189-8	2001	Rat cortex and cerebellum synaptosomes also showed a high-affinity Na(+)-dependent component of glycine uptake, with affinities similar to those observed for uptake in GlyT-1c or GlyT-2 cells.	Glycine	96-103	solute carrier family 6 member 5	Rattus norvegicus	179-185
11414709-4	2001	Substitution analysis showed that the C-terminal optimal sequence of GPR54-activating peptides is Gly-Leu-Arg-Trp-NH2.	Glycine	98-101	KISS1 receptor	Homo sapiens	69-74
12445460-4	2002	Both the N-terminal regulatory domain of annexin XI (Anx11N) and the ALG-2-binding domain of Alix/AIP1 are rich in Pro, Gly, Ala, Tyr and Gln.	Glycine	120-123	programmed cell death 6 interacting protein	Homo sapiens	93-97
20332777-1	2010	BACKGROUND: A synonymous single nucleotide polymorphism (SNP) rs172378 (A&gt;G, Gly-&gt;Gly) in the complement component C1QA has been proposed to be associated with distant breast cancer metastasis.	Glycine	80-83	complement C1q A chain	Homo sapiens	121-125
12445460-4	2002	Both the N-terminal regulatory domain of annexin XI (Anx11N) and the ALG-2-binding domain of Alix/AIP1 are rich in Pro, Gly, Ala, Tyr and Gln.	Glycine	120-123	programmed cell death 6 interacting protein	Homo sapiens	98-102
20332777-1	2010	BACKGROUND: A synonymous single nucleotide polymorphism (SNP) rs172378 (A&gt;G, Gly-&gt;Gly) in the complement component C1QA has been proposed to be associated with distant breast cancer metastasis.	Glycine	88-91	complement C1q A chain	Homo sapiens	121-125
12379114-5	2002	The peptides were also tested for the inhibition of the binding of factor Va to membrane-bound active site fluorescent labeled Glu-Gly-Arg human factor Xa ([OG488]-EGR-hXa).	Glycine	131-134	amylase alpha 2B	Homo sapiens	152-154
11412103-4	2001	Omission of the (Gly)(3) linker connecting the coiled-coiled helices and the integrin tails lead to helix propagation into the beta3 tail extending up to eight residues.	Glycine	17-20	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	127-132
20147285-7	2010	In contrast, in the open form of sMBP, all of the mutations are accessible, and the main chain of Tyr(62)-Gly(69) is destabilized and occupies an alternative conformation due to the W62Y mutation.	Glycine	106-109	transmembrane 9 superfamily member 3	Homo sapiens	33-37
11397844-4	2001	The present study examined whether this stimulation is dependent on binding of the Arg-Gly-Asp (RGD) domain of IGFBP-1 to an RGD binding site on the alpha 5 beta 1 integrin, followed by activation of focal adhesion kinase (FAK) and stimulation of the mitogen-activated protein kinase (MAPK) pathway.	Glycine	87-90	insulin like growth factor binding protein 1	Homo sapiens	111-118
11397844-6	2001	Migration stimulation by IGFBP-1 was abrogated by pretreatment with a Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP), but not a Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) hexapeptide, and by mutation of the RGD domain of IGFBP-1 to Trp-Gly-Asp (WGD).	Glycine	70-73	insulin like growth factor binding protein 1	Homo sapiens	25-32
12369818-3	2002	To verify the conclusion further and obtain more detailed structural information about this PUF, five hydrophobic core residues in the N-terminal helix were mutated to Gly and Asp to destabilize the native state selectively and populate the PUF for structural studies.	Glycine	168-171	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	92-95
20168080-4	2010	This allows for a continuous association interface centered on helix-helix glycine-packing and an unusual alphaIIb(GFF) structural motif that packs the conserved Phe-Phe residues against the beta3 transmembrane helix, enabling alphaIIb(D723)beta3(R995) electrostatic interactions.	Glycine	75-82	basic helix-loop-helix family member e22	Homo sapiens	191-196
12161434-6	2002	Increases in cSHMT expression inhibit SAM concentrations by two proposed mechanisms: (1) cSHMT-catalyzed serine synthesis competes with the enzyme methylenetetrahydrofolate reductase for methylenetetrahydrofolate in a glycine-dependent manner, and (2) cSHMT, a high affinity 5-methyltetrahydrofolate-binding protein, sequesters this cofactor and inhibits methionine synthesis in a glycine-independent manner.	Glycine	381-388	serine hydroxymethyltransferase 1	Homo sapiens	13-18
12161434-6	2002	Increases in cSHMT expression inhibit SAM concentrations by two proposed mechanisms: (1) cSHMT-catalyzed serine synthesis competes with the enzyme methylenetetrahydrofolate reductase for methylenetetrahydrofolate in a glycine-dependent manner, and (2) cSHMT, a high affinity 5-methyltetrahydrofolate-binding protein, sequesters this cofactor and inhibits methionine synthesis in a glycine-independent manner.	Glycine	381-388	serine hydroxymethyltransferase 1	Homo sapiens	89-94
12161434-6	2002	Increases in cSHMT expression inhibit SAM concentrations by two proposed mechanisms: (1) cSHMT-catalyzed serine synthesis competes with the enzyme methylenetetrahydrofolate reductase for methylenetetrahydrofolate in a glycine-dependent manner, and (2) cSHMT, a high affinity 5-methyltetrahydrofolate-binding protein, sequesters this cofactor and inhibits methionine synthesis in a glycine-independent manner.	Glycine	381-388	serine hydroxymethyltransferase 1	Homo sapiens	89-94
11397844-6	2001	Migration stimulation by IGFBP-1 was abrogated by pretreatment with a Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP), but not a Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) hexapeptide, and by mutation of the RGD domain of IGFBP-1 to Trp-Gly-Asp (WGD).	Glycine	70-73	insulin like growth factor binding protein 1	Homo sapiens	197-204
11386852-4	2001	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible reaction of serine and tetrahydrofolate (THF) to glycine and 5,10-methylene THF.	Glycine	113-120	serine hydroxymethyltransferase 1	Homo sapiens	0-31
11386852-4	2001	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible reaction of serine and tetrahydrofolate (THF) to glycine and 5,10-methylene THF.	Glycine	113-120	serine hydroxymethyltransferase 1	Homo sapiens	33-37
20407581-0	2010	Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca-Dependent Outward Rectification.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	34-38
12354619-6	2002	In addition, GlyT2a shows a severe limitation for reverse uptake, which suggests an essential role of GlyT2a in maintaining a high intracellular glycine pool, thus facilitating the refilling of synaptic vesicles by the low affinity, low specificity vesicular transporter VGAT/VIAAT.	Glycine	145-152	solute carrier family 32 member 1	Homo sapiens	276-281
20407581-4	2010	In contrast, recombinant receptors composed of NR1 and the glycine binding NR3A and/or NR3B subunits lack glutamate binding sites and can be activated by glycine alone.	Glycine	59-66	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	75-79
20407581-4	2010	In contrast, recombinant receptors composed of NR1 and the glycine binding NR3A and/or NR3B subunits lack glutamate binding sites and can be activated by glycine alone.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	75-79
20407581-8	2010	Whole-cell current-voltage relations of glycine currents recorded from NR1/NR3B and NR1/NR3A/NR3B expressing oocytes were found to be linear under our recording conditions.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	88-92
12237254-6	2002	5 The proportion of 5-HT(1A) receptor binding sites detected by [(3)H]-MPPF that displayed high affinity for 8-OH-DPAT was significantly greater when the interacting G protein contained isoleucine rather than glycine at residue(351).	Glycine	209-216	5-hydroxytryptamine receptor 1A	Homo sapiens	20-37
11336656-8	2001	For alpha1 integrin/protein binding, the conserved Lys-Ile-Gly-Phe-Phe-Lys-Arg motif and, in particular, the two lysine residues, are important.	Glycine	59-62	adrenoceptor alpha 1D	Homo sapiens	4-10
12237254-8	2002	7 These results indicate that a higher avidity ternary complex is formed between 8-OH-DPAT, the 5-HT(1A) receptor and G proteins when isoleucine rather than glycine is located at residue(351) of the interacting G protein.	Glycine	157-164	5-hydroxytryptamine receptor 1A	Homo sapiens	96-113
19477666-7	2010	Sequence analysis of COL4A1 revealed the heterozygous missense mutation c.2263G--&gt;A in exon 30, responsible for a glycine-to-arginine substitution (p.Gly755Arg) in both the index case and mother.	Glycine	117-124	collagen type IV alpha 1 chain	Homo sapiens	21-27
11341845-8	2001	Both THPs were hydrolyzed by MMP-1 at the Gly approximately Leu bond, analogous to the bond cleaved in the native collagen.	Glycine	42-45	matrix metallopeptidase 1	Homo sapiens	29-34
19825850-8	2010	The glycine-specific transporter, GLYT1, mediates osmoregulated glycine accumulation in mouse embryos and likely in human embryos.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	34-39
11328605-2	2001	The two cysteines in the N-terminal FAD domain (-Cys59-x-x-x-x-Cys64-) and histidine (His472) are conserved between them at corresponding positions, but the mammalian thioredoxin reductase contains a C-terminal extension of selenocysteine (Sec or U) at the penultimate position and a preceding cysteine (-Gly-Cys497-Sec498-Gly).	Glycine	305-308	thioredoxin	Homo sapiens	167-178
11328605-2	2001	The two cysteines in the N-terminal FAD domain (-Cys59-x-x-x-x-Cys64-) and histidine (His472) are conserved between them at corresponding positions, but the mammalian thioredoxin reductase contains a C-terminal extension of selenocysteine (Sec or U) at the penultimate position and a preceding cysteine (-Gly-Cys497-Sec498-Gly).	Glycine	323-326	thioredoxin	Homo sapiens	167-178
12401451-3	2002	In the absence of KCC2 and glutamatergic transmission, newborn VIAAT-labeled boutons contained GlyT2, released glycine, and accumulated postsynaptic gephyrin and GlyRs.	Glycine	111-118	solute carrier family 32 member 1	Homo sapiens	63-68
12082110-6	2002	Although having no direct effect on PAI-1 activity itself, HKa domain 5 or the peptide Gly(486)-Lys(502) markedly destabilized the VN.PAI-1 complex interaction, resulting in a significant reduction of PAI-1 inhibitory function on plasminogen activators, resembling the effect of VN antibodies that prevent stabilization of PAI-1.	Glycine	87-90	serpin family E member 1	Homo sapiens	134-139
12082110-6	2002	Although having no direct effect on PAI-1 activity itself, HKa domain 5 or the peptide Gly(486)-Lys(502) markedly destabilized the VN.PAI-1 complex interaction, resulting in a significant reduction of PAI-1 inhibitory function on plasminogen activators, resembling the effect of VN antibodies that prevent stabilization of PAI-1.	Glycine	87-90	serpin family E member 1	Homo sapiens	134-139
12082110-6	2002	Although having no direct effect on PAI-1 activity itself, HKa domain 5 or the peptide Gly(486)-Lys(502) markedly destabilized the VN.PAI-1 complex interaction, resulting in a significant reduction of PAI-1 inhibitory function on plasminogen activators, resembling the effect of VN antibodies that prevent stabilization of PAI-1.	Glycine	87-90	serpin family E member 1	Homo sapiens	134-139
12082110-8	2002	Taken together, our data indicate that the peptide Gly(486)-Lys(502) derived from domain 5 of HKa serves to interfere with PAI-1 function.	Glycine	51-54	serpin family E member 1	Homo sapiens	123-128
19751394-2	2010	The NMDAR contains a glycine binding site in its NR1 subunit that may be a useful target for the treatment of schizophrenia.	Glycine	21-28	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	4-9
12213887-5	2002	The IRS-1 Gly(972)Arg allele frequencies were identical in whites and African-Americans [0.95 (Gly) and 0.05 (Arg)].	Glycine	10-13	insulin receptor substrate 1	Homo sapiens	4-9
12213887-6	2002	The IRS-2 Gly(1057)Asp allele frequencies were 0.85 (Gly) and 0.15 (Asp) in African-Americans and 0.59 (Gly) and 0.41 (Asp) in whites.	Glycine	10-13	insulin receptor substrate 2	Homo sapiens	4-9
12213887-6	2002	The IRS-2 Gly(1057)Asp allele frequencies were 0.85 (Gly) and 0.15 (Asp) in African-Americans and 0.59 (Gly) and 0.41 (Asp) in whites.	Glycine	53-56	insulin receptor substrate 2	Homo sapiens	4-9
12213887-8	2002	However, nondiabetic subjects with the IRS-2 Gly/Gly genotype had significantly higher 2-h oral glucose tolerance test glucose levels compared with those with Gly/Asp and Asp/Asp genotypes in whites or Gly/Asp genotype in African-Americans (there were no Asp/Asp subjects in our modest size African-American sample).	Glycine	45-48	insulin receptor substrate 2	Homo sapiens	39-44
12213887-8	2002	However, nondiabetic subjects with the IRS-2 Gly/Gly genotype had significantly higher 2-h oral glucose tolerance test glucose levels compared with those with Gly/Asp and Asp/Asp genotypes in whites or Gly/Asp genotype in African-Americans (there were no Asp/Asp subjects in our modest size African-American sample).	Glycine	49-52	insulin receptor substrate 2	Homo sapiens	39-44
12213887-8	2002	However, nondiabetic subjects with the IRS-2 Gly/Gly genotype had significantly higher 2-h oral glucose tolerance test glucose levels compared with those with Gly/Asp and Asp/Asp genotypes in whites or Gly/Asp genotype in African-Americans (there were no Asp/Asp subjects in our modest size African-American sample).	Glycine	49-52	insulin receptor substrate 2	Homo sapiens	39-44
12213887-8	2002	However, nondiabetic subjects with the IRS-2 Gly/Gly genotype had significantly higher 2-h oral glucose tolerance test glucose levels compared with those with Gly/Asp and Asp/Asp genotypes in whites or Gly/Asp genotype in African-Americans (there were no Asp/Asp subjects in our modest size African-American sample).	Glycine	49-52	insulin receptor substrate 2	Homo sapiens	39-44
11293527-4	2001	Pretreatment with 20% glycine increased significantly (p &lt; 0.05) mucosal protein and deoxyribonucleic acid content, reduced intestinal myeloperoxidase activity, and maintained mucosal glutaminase activity.	Glycine	22-29	myeloperoxidase	Rattus norvegicus	138-153
11257542-2	2001	DnaJ is characterised by the presence of four distinct domains: the J-domain, glycine/phenylalanine-rich (G/F), cysteine-rich (Zn-finger) and C-terminal regions.	Glycine	78-85	DnaJ	Escherichia coli	0-4
19751394-2	2010	The NMDAR contains a glycine binding site in its NR1 subunit that may be a useful target for the treatment of schizophrenia.	Glycine	21-28	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	49-52
19751394-4	2010	The effects of eliminating DAO function were investigated in mice that display schizophrenia-related behavioral deficits due to a mutation (Grin 1(D481N)) in the NR1 subunit that results in a reduction in NMDAR glycine affinity.	Glycine	211-218	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	140-146
12385583-10	2002	In the present study, mutation of the p53 gene was detected in three DMBA-induced leukemias as follows: a single-base substitution (CAT to CGT) at codon 177 (exon 5), resulting in an amino-acid change from Arg to Leu, a CGG to CTG/CGG changed at codon 211 (exon 6) resulting in an amino-acid change from His to Arg/His, and a GGG to TGG at codon 242 (exon 6) resulting in an amino-acid change from Gly to Trp, respectively.	Glycine	398-401	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	38-41
19751394-4	2010	The effects of eliminating DAO function were investigated in mice that display schizophrenia-related behavioral deficits due to a mutation (Grin 1(D481N)) in the NR1 subunit that results in a reduction in NMDAR glycine affinity.	Glycine	211-218	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	162-165
19751394-8	2010	Thus, an increased level of D-serine resulting from decreased catalysis corrected the performance of mice with deficient NMDAR glycine site activation in behavioral tasks relevant to the negative and cognitive symptoms of schizophrenia.	Glycine	127-134	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	121-126
19766158-8	2010	This protective effect was only present in combination with DRD3 Ser/Ser genotype because of the significant interaction between 9/10 and both Ser/Gly [OR=2.45 (95% CI=1.16-5.17), p=0.019] and Gly/Gly [OR=3.80 (95% CI=1.24-11.63), p=0.019].	Glycine	147-150	dopamine receptor D3	Homo sapiens	60-64
12145107-5	2002	3: Hyperpolarizations to orphanin FQ/nociceptin were not altered by tetrodotoxin or the opioid receptor antagonist naloxone, but were reduced by the opioid receptor-like orphan receptor antagonist [Phe1(1)phiCH(2)-NH)Gly(2)]NC(1-13)NH(2) (1 microM).	Glycine	217-220	prepronociceptin	Rattus norvegicus	25-36
12145107-5	2002	3: Hyperpolarizations to orphanin FQ/nociceptin were not altered by tetrodotoxin or the opioid receptor antagonist naloxone, but were reduced by the opioid receptor-like orphan receptor antagonist [Phe1(1)phiCH(2)-NH)Gly(2)]NC(1-13)NH(2) (1 microM).	Glycine	217-220	prepronociceptin	Rattus norvegicus	37-47
11259500-0	2001	Glycine is taken up through GLYT1 and GLYT2 transporters into mouse spinal cord axon terminals and causes vesicular and carrier-mediated release of its proposed co-transmitter GABA.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	28-33
11259500-0	2001	Glycine is taken up through GLYT1 and GLYT2 transporters into mouse spinal cord axon terminals and causes vesicular and carrier-mediated release of its proposed co-transmitter GABA.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	38-43
11259500-7	2001	The glycine effect was halved by sarcosine, a GLYT1 substrate/inhibitor, or by amoxapine, a GLYT2 blocker, and abolished by a mixture of the two.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	46-51
11259500-7	2001	The glycine effect was halved by sarcosine, a GLYT1 substrate/inhibitor, or by amoxapine, a GLYT2 blocker, and abolished by a mixture of the two.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	92-97
11259500-9	2001	To conclude, in mice spinal cord, transporters for glycine (both GLYT1 and GLYT2) and for GABA coexist on the same axon terminals.	Glycine	51-58	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	65-70
19917609-6	2010	Furthermore, in relation to wild-type ALAS, the catalytic efficiency of S254A toward glycine improved approximately 3-fold, whereas that of S254T diminished approximately 3-fold.	Glycine	85-92	aminolevulinic acid synthase 1	Mus musculus	38-42
11259500-9	2001	To conclude, in mice spinal cord, transporters for glycine (both GLYT1 and GLYT2) and for GABA coexist on the same axon terminals.	Glycine	51-58	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	75-80
12487019-1	2002	Aminomethyltransferase (Amt), also called glycine cleavage system T-protein is an important enzyme in glycine metabolism (EC 2.1.2.10).	Glycine	42-49	aminomethyltransferase	Mus musculus	0-22
12487019-1	2002	Aminomethyltransferase (Amt), also called glycine cleavage system T-protein is an important enzyme in glycine metabolism (EC 2.1.2.10).	Glycine	42-49	aminomethyltransferase	Mus musculus	24-27
20080556-6	2010	The targeting species employed in this work is a cyclic nine-amino acid peptide LyP-1 (Cys-Gly-Asn-Lys-Arg-Thr-Arg-Gly-Cys) that binds to the stress-related protein, p32, which we find to be upregulated on the surface of tumor-associated cells upon thermal treatment.	Glycine	91-94	complement component 1, q subcomponent binding protein	Mus musculus	166-169
12151550-4	2002	In this study we have characterized compound heterozygote Grin1(D481N/K483Q) mice, which are viable and exhibited biphasic NMDA receptor glycine affinities compatible with the presence of each of the two mutated alleles.	Glycine	137-144	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	58-63
12151550-5	2002	Grin1(D481N/K483Q) mice exhibited a marked NMDA receptor hypofunction revealed by deficits in hippocampal long-term potentiation, which were rescued by the glycine site agonist d-serine, which also facilitated NMDA synaptic currents in mutant, but not in wild-type, mice.	Glycine	156-163	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	0-5
12147347-2	2002	We have successfully engineered a series of model proteins, each containing a single EF-hand loop but with increasing numbers of Gly residues linking the EF-hand loop to a scaffold protein, cluster of differentiation 2 (CD2), to obtain the site-specific calcium-binding ability of a protein with EF-hand motifs without the interference of cooperativity.	Glycine	129-132	CD2 molecule	Homo sapiens	220-223
11160487-8	2001	Only LT-evoked field potentials were found to be reliably inhibited by the mu opioid receptor agonist [D-Ala(2), N-Me-Phe(4), Gly(5)] enkephalin-ol (DAMGO, 1 microM), although evoked potentials from both DR and LT were blocked by the AMPA/kainate glutamate receptor antagonist 6-cyano-7-nitroquinoxalene-2,3-dione.	Glycine	126-129	proenkephalin	Rattus norvegicus	134-144
11148034-1	2001	We have explored the ability of a nucleoside diphosphate kinase (NDPK) mutant in which the nucleophilic histidine has been replaced by glycine (H122G) to transfer phosphate from ATP to alcohols of varying pK(a), size, shape, and polarity.	Glycine	135-142	cytidine/uridine monophosphate kinase 2	Homo sapiens	34-63
11148034-1	2001	We have explored the ability of a nucleoside diphosphate kinase (NDPK) mutant in which the nucleophilic histidine has been replaced by glycine (H122G) to transfer phosphate from ATP to alcohols of varying pK(a), size, shape, and polarity.	Glycine	135-142	cytidine/uridine monophosphate kinase 2	Homo sapiens	65-69
19766149-9	2010	In PC-12 cells, GABARAP was constitutively and quantitatively cleaved at the C-terminus peptide bond and this cleavage was prevented by mutation of Gly(116).	Glycine	148-151	GABA type A receptor-associated protein	Rattus norvegicus	16-23
12065727-2	2002	Nevertheless, over the past 10 years, several groups have characterized new binding sites using peptides related to gastrin (particularly glycine-extended forms of gastrin) on various tumoral and nontumoral cell lines.	Glycine	138-145	gastrin	Homo sapiens	116-123
12065727-2	2002	Nevertheless, over the past 10 years, several groups have characterized new binding sites using peptides related to gastrin (particularly glycine-extended forms of gastrin) on various tumoral and nontumoral cell lines.	Glycine	138-145	gastrin	Homo sapiens	164-171
20173309-1	2010	Glycine is an inhibitory neurotransmitter in the spinal dorsal horn and its extracellular concentration is regulated by glial glycine transporter (GlyT) 1 and neuronal GlyT2.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	126-154
12052894-2	2002	Alignment of the HIC1 and HRG22 proteins from various species highlighted a perfectly conserved GLDLSKK/R motif highly related to the consensus CtBP interaction motif (PXDLSXK/R), except for the replacement of the virtually invariant proline by a glycine.	Glycine	247-254	HIC ZBTB transcriptional repressor 1	Homo sapiens	17-21
11732605-7	2001	Contacts between MetRS and other proteins could be mediated not only by noncatalytic peptides but also by structural elements present in the catalytic core, e.g. Arg-Gly-Asp (RGD) motifs.	Glycine	166-169	methionyl-tRNA synthetase 1	Homo sapiens	17-22
20173309-1	2010	Glycine is an inhibitory neurotransmitter in the spinal dorsal horn and its extracellular concentration is regulated by glial glycine transporter (GlyT) 1 and neuronal GlyT2.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	168-173
12071739-15	2002	Repositioning of the N-terminal part of the peptide on CyP.TS formation becomes more pronounced when the substrate X residue is changed from Gly &lt; Trp &lt; Ala &lt; Leu.	Glycine	141-144	peptidylprolyl isomerase G	Homo sapiens	55-58
19759529-4	2010	Among them are glycine transporter-1 (GlyT1) inhibitors such as SSR103800, which indirectly enhance NMDA receptor function by increasing the glycine (a co-agonist for the NMDA receptor) levels in the synapse.	Glycine	15-22	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	38-43
11997663-6	2002	Overexpression of a mutant USH3 domain (Gly --&gt; Ala), that disrupts membrane localization, did not induce high level of apoptosis.	Glycine	40-43	clarin 1	Homo sapiens	27-31
11095995-1	2001	Gephyrin was originally identified as a membrane-associated protein that is essential for the postsynaptic localization of receptors for the neurotransmitters glycine and GABA(A).	Glycine	159-166	gephyrin	Homo sapiens	0-8
19778585-7	2009	Absence of BDNF and NT-3 resulted in the emergence of glycine-induced currents; however, GlyR currents were absent from the short term cultured SGN.	Glycine	54-61	brain derived neurotrophic factor	Mus musculus	11-15
11726031-3	2001	TRX is a small ubiquitous protein with the redox-active site sequence -Cys-Gly-Pro-Cys-.	Glycine	75-78	thioredoxin	Homo sapiens	0-3
11099486-1	2001	Molecular scanning of human IRS-1 gene revealed a common polymorphism causing Gly--&gt;Arg972 change.	Glycine	78-81	insulin receptor substrate 1	Homo sapiens	28-33
12068077-1	2002	Coexpression of PSD-95(c-Myc) with NR1-1a/NR2A NMDA receptors in human embryonic kidney (HEK) 293 cells resulted in a decrease in efficacy for the glycine stimulation of [3 H]MK801 binding similar to that previously described for l-glutamate.	Glycine	147-154	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	23-28
11886857-5	2002	In Western blotting, 38-, 39-, 41-, and 41.5-kDa components were all recognized by antibodies against a peptide in the glycine-rich region of hnRNP A3, but only the 41- and 41.5-kDa bands bound antibodies to a 15-residue N-terminal peptide encoded by an alternatively spliced part of exon 1.	Glycine	119-126	heterogeneous nuclear ribonucleoprotein A3	Rattus norvegicus	142-150
19778585-7	2009	Absence of BDNF and NT-3 resulted in the emergence of glycine-induced currents; however, GlyR currents were absent from the short term cultured SGN.	Glycine	54-61	neurotrophin 3	Mus musculus	20-24
12113291-8	2002	In both individuals, mutations causing an impaired LDL receptor function (2 bp insertion in exon 3 and Glu119 --&gt; Gly mutation in exon 4) were identified.	Glycine	117-120	low density lipoprotein receptor	Homo sapiens	51-63
20306720-5	2009	With respect to the inhibitory neurotransmitter levels, in the group exposed to PQ, the more important changes were observed in Gly between P1 and P15.	Glycine	128-131	zinc finger protein 185	Mus musculus	140-150
11978638-0	2002	Insulin secretory function is impaired in isolated human islets carrying the Gly(972)--&gt;Arg IRS-1 polymorphism.	Glycine	77-80	insulin receptor substrate 1	Homo sapiens	95-100
11173539-5	2001	Mutations of Smad2 were detected in 2 out of 12 HCCs (16.7%) induced by the CDAA diet, a GGT-to-GGC transition (Gly to Gly) at codon 30 and a TCT-to-GCT (Ser to Ala) transversion at codon 118, without any TGF-betaRII or Smad4 alterations.	Glycine	112-115	SMAD family member 2	Rattus norvegicus	13-18
11173539-5	2001	Mutations of Smad2 were detected in 2 out of 12 HCCs (16.7%) induced by the CDAA diet, a GGT-to-GGC transition (Gly to Gly) at codon 30 and a TCT-to-GCT (Ser to Ala) transversion at codon 118, without any TGF-betaRII or Smad4 alterations.	Glycine	119-122	SMAD family member 2	Rattus norvegicus	13-18
11978638-3	2002	Recently, the common Gly(972)--&gt;Arg amino acid polymorphism of insulin receptor substrate 1 (Arg(972) IRS-1) has been associated with human type 2 diabetes.	Glycine	21-24	insulin receptor substrate 1	Homo sapiens	66-94
20041218-11	2009	We found a G&lt;--&gt;A transition at position 1448, causing a Gly to Glu substitution (Gly483Glu) in the highly conserved N-terminal RCC1-like domain of the HERC1 protein.	Glycine	63-66	regulator of chromosome condensation 1	Mus musculus	134-138
11978638-3	2002	Recently, the common Gly(972)--&gt;Arg amino acid polymorphism of insulin receptor substrate 1 (Arg(972) IRS-1) has been associated with human type 2 diabetes.	Glycine	21-24	insulin receptor substrate 1	Homo sapiens	105-110
11978638-11	2002	These alterations may account for the increased predisposition to type 2 diabetes in individuals carrying the Gly(972)--&gt;Arg amino acid polymorphism of IRS-1.	Glycine	110-113	insulin receptor substrate 1	Homo sapiens	155-160
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	135-138	proprotein convertase subtilisin/kexin type 1	Homo sapiens	80-83
11929983-4	2002	We show here, using NMR exchange spectroscopy, that CypA does not only bind to CA(N) but also catalyzes efficiently the cis/trans isomerization of the Gly-89-Pro-90 peptide bond.	Glycine	151-154	peptidylprolyl isomerase A	Homo sapiens	52-56
11983426-11	2002	The enzyme also cleaved an N-terminal synthetic peptide of bovine annexin II (Gly(24)-Ser-Val-Lys-Ala-Tyr-Thr(30)-Asn-Phe-Asp-Ala-Glu(35)-Arg-Asp(37)) at a position between Asn(31) and Phe(32).	Glycine	78-81	annexin A2	Bos taurus	66-76
11490179-2	2001	Previous studies have demonstrated an association between a serine to glycine polymorphism in the first exon of the DRD3 gene and TD; however, the results have been inconsistent.	Glycine	70-77	dopamine receptor D3	Homo sapiens	116-120
11490179-5	2001	The mean AIMS score for patients carrying the heterozygote (DRD3(ser-gly)) was significantly greater than for those with the homozygotes (DRD3(ser-ser) and DRD3(gly-gly)).	Glycine	69-72	dopamine receptor D3	Homo sapiens	60-64
11734363-8	2001	Enkephalin-positive terminals synapsing on bulbospinal barosensitive neurons contained one or more amino acid: GABA+glycine, glutamate alone or GABA+glutamate.	Glycine	116-123	proenkephalin	Rattus norvegicus	0-10
19744243-3	2009	This is the first report of an inorganic pyrophosphatase belonging to the haloacid dehalogenase superfamily, in which unique residues in motif I and II have been replaced with Trp and Gly, respectively.	Glycine	184-187	inorganic diphosphatase	Thermococcus onnurineus NA1	31-56
11996368-2	2002	The simultaneous analysis of the titration of peptide with metal and of metal with peptide allowed the resolution of the Cd2+/Cys-Gly system, whereas in the analysis of the Cd2+/gamma-Glu-Cys system the analysis of a single titration experiment was sufficient.	Glycine	130-133	CD2 molecule	Homo sapiens	121-124
19659572-4	2009	Here, we demonstrate that FMRP is required for glycine induced LTP (Gly-LTP) in the CA1 of hippocampus.	Glycine	47-54	carbonic anhydrase 1	Mus musculus	84-87
11861805-4	2002	In this report, we investigated the role of protein kinase C (PKC) and protein kinase A (PKA) in ethanol-induced inhibition of glycine-activated current, using whole-cell patch-clamp technique.	Glycine	127-134	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	71-87
11734363-11	2001	Enkephalin is present in both excitatory (glutamate-immunoreactive) and inhibitory (GABA- and/or glycine-immunoreactive) terminals.	Glycine	97-104	proenkephalin	Rattus norvegicus	0-10
11720127-4	2001	In a zona-free hamster egg penetration assay, the egg penetration index was higher (P&lt;0.001) with nongly-glycodelin-treated spermatozoa (3.4 +/- 0.3) than with gly-glycodelin-treated spermatozoa (0.4 +/- 0.1) and untreated spermatozoa (1.6 +/- 0.2).	Glycine	104-107	progestagen associated endometrial protein	Homo sapiens	108-118
11861805-4	2002	In this report, we investigated the role of protein kinase C (PKC) and protein kinase A (PKA) in ethanol-induced inhibition of glycine-activated current, using whole-cell patch-clamp technique.	Glycine	127-134	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	89-92
11720127-6	2001	However, the AR rate was higher (P&lt;0.01) in nongly-glycodelin-treated spermatozoa (39.4 +/- 1.6%) than in either gly-glycodelin-treated spermatozoa (19.3 +/- 2.0%) or untreated controls (30.0 +/- 1.2%).	Glycine	50-53	progestagen associated endometrial protein	Homo sapiens	54-64
19659572-4	2009	Here, we demonstrate that FMRP is required for glycine induced LTP (Gly-LTP) in the CA1 of hippocampus.	Glycine	68-71	carbonic anhydrase 1	Mus musculus	84-87
19389270-1	2009	SummaryWe have investigated whether culture in glycine-containing medium affects subsequent glycine transport by the specific transport system, GLYT1, which is the sole glycine transporter in fertilized mouse ova.	Glycine	47-54	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	144-149
11720127-7	2001	Moreover, the in vitro fertilization rate was significantly (P&lt;0.01) higher with nongly-glycodelin treated-spermatozoa compared with untreated spermatozoa (77.5 +/- 2.3% v. 52.9 +/- 4.3%) and gly-glycodelin-treated spermatozoa (38.3 +/- 6.5%; P&lt;0.05).	Glycine	87-90	progestagen associated endometrial protein	Homo sapiens	91-101
11748245-9	2002	Interpretation of these results in light of the high-resolution structures of (Ca(2+))(4)-CaM, free and complexed with the CaM-binding domain of MLCK, indicates that a surface domain containing Lys(30) and Gly(40) and residues from the C-terminal domain is created upon binding to MLCK, formation of which is required for activation of MLCK.	Glycine	206-209	myosin light chain kinase	Homo sapiens	145-149
19389270-1	2009	SummaryWe have investigated whether culture in glycine-containing medium affects subsequent glycine transport by the specific transport system, GLYT1, which is the sole glycine transporter in fertilized mouse ova.	Glycine	92-99	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	144-149
11861413-11	2002	Because the Ser1776 residue occupies a core position in the myosin rod at which the substitution of glycine is extremely energetically unfavorable, it is likely to disrupt the coiled-coil structure.	Glycine	100-107	myosin heavy chain 14	Homo sapiens	60-66
11118328-1	2000	We describe the genes for three new glycine-rich antimicrobial peptides in Drosophila, two attacins (AttC and AttD) and one diptericin (DptB).	Glycine	36-43	Attacin-D	Drosophila melanogaster	110-114
19645064-5	2009	The frequencies of the DRD3Ser/Gly and DRD3Gly/Gly genotypes and of the allelic variant DRD3Gly in patients were significantly higher in patients with voice tremor, but not with head, tongue, or chin tremor, than in controls.	Glycine	31-34	dopamine receptor D3	Homo sapiens	23-27
11188692-6	2000	This change significantly reduces the distances from the amide groups of p21 glycine residues 60 and 13 to the divalent metal ion.	Glycine	77-84	H3 histone pseudogene 16	Homo sapiens	73-76
11188692-7	2000	CONCLUSIONS: The movement of glycine residues 60 and 13 upon the binding of GAP-334 in solution provides a physical basis to interpret prior mutagenesis studies, which indicated that Gly-60 and Gly-13 of p21 play important roles in the GAP-dependent GTPase reaction.	Glycine	29-36	H3 histone pseudogene 16	Homo sapiens	204-207
11188692-7	2000	CONCLUSIONS: The movement of glycine residues 60 and 13 upon the binding of GAP-334 in solution provides a physical basis to interpret prior mutagenesis studies, which indicated that Gly-60 and Gly-13 of p21 play important roles in the GAP-dependent GTPase reaction.	Glycine	183-186	H3 histone pseudogene 16	Homo sapiens	204-207
11188692-7	2000	CONCLUSIONS: The movement of glycine residues 60 and 13 upon the binding of GAP-334 in solution provides a physical basis to interpret prior mutagenesis studies, which indicated that Gly-60 and Gly-13 of p21 play important roles in the GAP-dependent GTPase reaction.	Glycine	194-197	H3 histone pseudogene 16	Homo sapiens	204-207
11823786-2	2002	Conventional heteromeric NMDARs composed of NR1 and NR2A-D subunits require dual agonists, glutamate and glycine, for activation.	Glycine	105-112	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	44-47
11823786-9	2002	In cerebrocortical neurons containing NR3 family members, glycine triggers a burst of firing, and membrane patches manifest glycine-responsive single channels that are suppressible by D-serine.	Glycine	58-65	nodal homolog 3, gene 1 L homeolog	Xenopus laevis	38-41
11823786-9	2002	In cerebrocortical neurons containing NR3 family members, glycine triggers a burst of firing, and membrane patches manifest glycine-responsive single channels that are suppressible by D-serine.	Glycine	124-131	nodal homolog 3, gene 1 L homeolog	Xenopus laevis	38-41
11939517-0	2002	Hb Siam [alpha15(A13)Gly--&gt;Arg (alpha1) (GGT--&gt;CGT)] is a typical alpha chain hemoglobinopathy without an alpha-thalassemic effect.	Glycine	21-24	adrenoceptor alpha 1D	Homo sapiens	9-15
11188692-8	2000	Gly-60 and Gly-13 may play direct catalytic roles and stabilize the attacking water molecule and beta,gamma-bridging oxygen, respectively, in p21.	Glycine	0-3	H3 histone pseudogene 16	Homo sapiens	142-145
11188692-8	2000	Gly-60 and Gly-13 may play direct catalytic roles and stabilize the attacking water molecule and beta,gamma-bridging oxygen, respectively, in p21.	Glycine	11-14	H3 histone pseudogene 16	Homo sapiens	142-145
19501114-6	2009	To obtain further insight into the MC-PP2A interaction, we substituted cysteine at position 269 in PP2Ac with glycine.	Glycine	110-117	protein phosphatase 2 catalytic subunit alpha	Homo sapiens	99-104
11851882-7	2002	Analysis of these data implies that the epidermal cell envelopes have elevated levels of the small proline-rich proteins, and cell envelopes of both kinds contain other protein(s) that, like loricrin, are rich in glycine and serine.	Glycine	213-220	loricrin	Mus musculus	191-199
19664057-0	2009	Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro.	Glycine	64-71	gastrin	Homo sapiens	81-88
11730482-2	2001	A pentapeptide, Gly-Arg-Arg-Arg-Arg, corresponding to a region of the N-terminal portion of human Lf rich in basic amino acids, was synthesized and its intracellular localization was investigated.	Glycine	16-19	HLF transcription factor, PAR bZIP family member	Homo sapiens	98-100
11102680-13	2000	Thus the Gly-Gly-Gly linker exploits lysosomal cathepsin B to liberate T-2513 slowly and steadily, resulting in improved therapeutic efficacy.	Glycine	9-12	cathepsin B	Rattus norvegicus	47-58
11102680-13	2000	Thus the Gly-Gly-Gly linker exploits lysosomal cathepsin B to liberate T-2513 slowly and steadily, resulting in improved therapeutic efficacy.	Glycine	13-16	cathepsin B	Rattus norvegicus	47-58
19664057-2	2009	The peptides amidated gastrin(17) (Gamide) and glycine-extended gastrin(17) (Ggly) are well known for their roles in controlling acid secretion and as growth factors in the gastrointestinal tract.	Glycine	47-54	gastrin	Homo sapiens	64-71
11112475-2	2000	Although parvovirus isolates from three Vietnamese leopard cats were genetically related to CPV type 2a or 2b, they had a natural mutation of VP2 residue 300 Gly to an Asp, resulting in remarkable changes in their antigenic properties.	Glycine	158-161	VP2	Canine parvovirus	142-145
19562746-1	2009	5-Aminolevulinate synthase (ALAS) controls the rate-limiting step of heme biosynthesis in mammals by catalyzing the condensation of succinyl-coenzyme A and glycine to produce 5-aminolevulinate, coenzyme-A (CoA), and carbon dioxide.	Glycine	156-163	aminolevulinic acid synthase 1	Mus musculus	0-26
11085936-7	2000	Employing the PTEN Gly(129)--&gt;Glu mutant, which is selectively defective in lipid phosphatase activity, it was established that it is the lipid phosphatase activity that controls PKCdelta phosphorylation.	Glycine	19-22	phosphatase and tensin homolog	Homo sapiens	14-18
11743809-0	2001	Tumor-promoting effect of GGN-MRP extract from the Maillard reaction products of glucose and glycine in the presence of sodium nitrite in C3H10T1/2 cells.	Glycine	93-100	gametogenetin	Mus musculus	26-29
11743809-1	2001	GGN-MRP is an extract from the Maillard reaction products of nitrite with glucose and glycine in the Maillard browning system.	Glycine	86-93	gametogenetin	Mus musculus	0-3
19562746-1	2009	5-Aminolevulinate synthase (ALAS) controls the rate-limiting step of heme biosynthesis in mammals by catalyzing the condensation of succinyl-coenzyme A and glycine to produce 5-aminolevulinate, coenzyme-A (CoA), and carbon dioxide.	Glycine	156-163	aminolevulinic acid synthase 1	Mus musculus	28-32
10942762-9	2000	The microbicidal activities of recombinant cryptdin-4 and (des-Gly)-cryptdin-4 peptides against E. coli, and S. typhimurium showed that the N-terminal Gly residue or the length of the cryptdin-4 N terminus are determinants of microbicidal activity.	Glycine	63-66	defensin, alpha, 20	Mus musculus	68-78
19525417-2	2009	The ADE3 gene is known to encode a crucial one-carbon regulon enzyme, tetrahydrofolate synthase, which is involved in the biosynthesis of purine and the amino acids methionine and glycine.	Glycine	180-187	trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3	Saccharomyces cerevisiae S288C	4-8
10942762-9	2000	The microbicidal activities of recombinant cryptdin-4 and (des-Gly)-cryptdin-4 peptides against E. coli, and S. typhimurium showed that the N-terminal Gly residue or the length of the cryptdin-4 N terminus are determinants of microbicidal activity.	Glycine	63-66	defensin, alpha, 20	Mus musculus	68-78
11672422-6	2001	The CSRP2-encoded cysteine- and glycine-rich double-LIM-domain protein (CRP)2 is proposed to function as a molecular adapter, arranging two or more as yet unidentified protein constituents into a macromolecular complex.	Glycine	32-39	cysteine and glycine rich protein 2	Homo sapiens	4-9
19479271-10	2009	The other mutation was a transition mutation, c.676G&gt;A (G207E), which has been found in exon six of the PMS2 gene and caused an amino acid change of glycine to glutamic acid.	Glycine	152-159	PMS1 homolog 2, mismatch repair system component	Homo sapiens	107-111
11672422-6	2001	The CSRP2-encoded cysteine- and glycine-rich double-LIM-domain protein (CRP)2 is proposed to function as a molecular adapter, arranging two or more as yet unidentified protein constituents into a macromolecular complex.	Glycine	32-39	cysteine and glycine rich protein 2	Homo sapiens	72-77
10999946-8	2000	The difference in ICS sensitivity between alpha1 and alpha2 GlyRs cannot be explained by their difference in TM2 segment and extracellular domains partly conserved between glycine and 5-HT(3) receptors are probably involved in the interaction of some 5-HT(3) antagonists with GlyRs.	Glycine	172-179	adrenoceptor alpha 1D	Homo sapiens	42-48
11640930-2	2001	Here, the effect of Con-G on recombinant NMDA receptors carrying point mutations within the glycine and glutamate binding pockets of the NR1 and NR2B subunits was studied using whole-cell voltage-clamp recording from cRNA injected Xenopus oocytes.	Glycine	92-99	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	137-140
19494039-4	2009	Aurora A residue glycine 198 (G198), mutated to asparagine to mimic the aligned asparagine 142 (N142) of Aurora B, causes Aurora A to bind the Aurora B binding partner INCENP but not the Aurora A binding partner TPX2.	Glycine	17-24	inner centromere protein	Homo sapiens	168-174
19569705-5	2009	Ala-TrpH(+) and Gly-TrpH(+) exhibit an extensive spectral change with addition of two methanol molecules.	Glycine	16-19	tryptophan hydroxylase 1	Homo sapiens	20-24
11495676-8	2001	Affinity for glycine-extended gastrin-17 was not increased when compared to the wild-type CCK-B/gastrin receptor.	Glycine	13-20	gastrin	Homo sapiens	30-37
10995219-5	2000	The cSHMT SUTR-luciferase mRNA binds to the cSHMT.glycine.5-formyltetrahydrofolate ternary complex with an apparent K(d) of 10 microM.	Glycine	50-57	serine hydroxymethyltransferase 1	Homo sapiens	4-9
10995219-5	2000	The cSHMT SUTR-luciferase mRNA binds to the cSHMT.glycine.5-formyltetrahydrofolate ternary complex with an apparent K(d) of 10 microM.	Glycine	50-57	serine hydroxymethyltransferase 1	Homo sapiens	44-49
10995219-6	2000	Gel mobility shift assays demonstrate that the human cSHMT protein binds to the cSHMT LUTR-luciferase fusion mRNA in the presence and absence of glycine and 5-formyltetrahydrofolate pentaglutamate.	Glycine	145-152	serine hydroxymethyltransferase 1	Homo sapiens	53-58
11535048-10	2001	Fluorescence quenching experiments with peptides derived from the glycine-extended gastrin(17) sequence indicated that one or more of the five glutamic acid residues were necessary for iron binding.	Glycine	66-73	gastrin	Homo sapiens	83-90
11535048-11	2001	The binding of ferric ions by glycine-extended gastrin(17) at low pH is consistent with a role for progastrin-derived peptides in iron uptake from the lumen of the gastrointestinal tract.	Glycine	30-37	gastrin	Homo sapiens	47-54
19369251-5	2009	Covalent linkage of a PKG-specific substrate analogue was localized in the catalytic core on residues 356-372, also known as the glycine-rich loop, essential for ATP binding.	Glycine	129-136	protein kinase cGMP-dependent 1	Homo sapiens	22-25
11559512-1	2001	Elevated levels of glycine in the CSF have recently been documented in van der Knaap syndrome (diffuse leukoencephalopathy associated with cystic degeneration of the white matter).	Glycine	19-26	colony stimulating factor 2	Homo sapiens	34-37
11513728-0	2001	Heterogeneous nuclear ribonucleoprotein E1B-AP5 is methylated in its Arg-Gly-Gly (RGG) box and interacts with human arginine methyltransferase HRMT1L1.	Glycine	73-76	heterogeneous nuclear ribonucleoprotein U like 1	Homo sapiens	40-47
11513728-0	2001	Heterogeneous nuclear ribonucleoprotein E1B-AP5 is methylated in its Arg-Gly-Gly (RGG) box and interacts with human arginine methyltransferase HRMT1L1.	Glycine	77-80	heterogeneous nuclear ribonucleoprotein U like 1	Homo sapiens	40-47
10859302-7	2000	GAKIN sequence contains a motor domain at the NH(2) terminus, a central stalk domain, and a putative microtubule-interacting sequence called the CAP-Gly domain at the COOH terminus.	Glycine	149-152	kinesin family member 13B	Homo sapiens	0-5
11513728-5	2001	Here we report that E1B-AP5 is methylated in vivo in its Arg-Gly-Gly (RGG)-box domain, known to mediate protein-RNA interactions.	Glycine	61-64	heterogeneous nuclear ribonucleoprotein U like 1	Homo sapiens	20-27
19353679-5	2009	Genetic testing revealed a mutation of the KNCQ(1)-gene encoding serine instead of glycine.	Glycine	83-90	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	43-51
11513728-5	2001	Here we report that E1B-AP5 is methylated in vivo in its Arg-Gly-Gly (RGG)-box domain, known to mediate protein-RNA interactions.	Glycine	65-68	heterogeneous nuclear ribonucleoprotein U like 1	Homo sapiens	20-27
11509017-4	2001	Polymerase chain reaction (PCR)-based DNA sequence analysis of the LDH-B subunit gene revealed a heterozygous nucleotide change: a guanine to adenine substitution in codon 69 (GGG --&gt; GAG) at the third exon of the LDH-B subunit gene that resulted in a glycine to glutamic acid substitution (G69E).	Glycine	255-262	lactate dehydrogenase B	Homo sapiens	67-72
10851237-6	2000	Furthermore, the carboxyl-terminal arginine- and glycine-rich domain of Lsm4 directly interacts with SMN.	Glycine	49-56	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated	Homo sapiens	72-76
10944223-2	2000	In five HypoPP families without DHPR gene defects, we identified two mutations, Arg-672-->His and -->Gly, in the voltage sensor of domain 2 of a different protein: the skeletal muscle sodium channel alpha subunit, known to be responsible for hereditary muscle diseases associated with myotonia.	Glycine	101-104	sodium voltage-gated channel alpha subunit 4	Homo sapiens	168-212
19460156-12	2009	Co-incubations of AEA and glycine with recombinant FAAH did not, however, produce NAGly.	Glycine	26-33	fatty acid amide hydrolase	Mus musculus	51-55
11389828-2	2001	In the familial hypercholesterolemia (FH)-Turku LDL receptor allele, a mutation of glycine 823 residue affects the signal required for basolateral targeting in MDCK cells.	Glycine	83-90	low density lipoprotein receptor	Homo sapiens	7-36
19460156-13	2009	CONCLUSION: These data support the hypothesis that the signaling lipid NAGly is a metabolic product of AEA by both oxidative metabolism of the AEA ethanolamine moiety and through the conjugation of glycine to AA that is released during AEA hydrolysis by FAAH.	Glycine	198-205	fatty acid amide hydrolase	Mus musculus	254-258
10891502-6	2000	The present experiments, performed with an extensive panel of site-directed mutations within each of the six kelch motifs, further support the critical role of both hydrophobic and glycine-rich regions within the second beta-strand for RAG1-RAG2 interaction and recombination signal recognition and cleavage.	Glycine	181-188	recombination activating 1	Homo sapiens	236-240
19326097-3	2009	Bioinformatic analysis revealed that VVA0331 consist of nineteen 87-amino acid repeats, two Arg-Gly-Asp motifs, four cysteine residues, an outer membrane protein domain, a polysaccharide-binding site and several motifs related to cell adhesions.	Glycine	96-99	BJE04_RS17365	Vibrio vulnificus YJ016	37-44
10891502-6	2000	The present experiments, performed with an extensive panel of site-directed mutations within each of the six kelch motifs, further support the critical role of both hydrophobic and glycine-rich regions within the second beta-strand for RAG1-RAG2 interaction and recombination signal recognition and cleavage.	Glycine	181-188	recombination activating 2	Homo sapiens	241-245
10845864-4	2000	Cultured VSMCs from Wistar-Kyoto rats were incubated with an active fragment of FN, Arg-Gly-Asp-Ser, for 24, 48, or 72 hours after synchronization of the cell cycle with 0.	Glycine	88-91	fibronectin 1	Rattus norvegicus	80-82
11352090-1	2001	A biocompatible hydrogel of poly[N-(2-hydroxypropyl)methacrylamide] (PHPMA) which includes the cell-adhesive region of fibronectin Arg-Gly-Asp was synthesized and its structure, rheological and dielectric properties were characterized.	Glycine	135-138	fibronectin 1	Rattus norvegicus	119-130
11306716-5	2001	The docking of synthetic compounds bearing C-11beta hydrophobic substituents within the ligand binding pocket of hAR demonstrated that precise positions of the steroid, such as C-11 and C-17, are in close contact with some residues on the receptor, C-11 with Gly 708 and C-17 with Asn705 and Thr877.	Glycine	259-262	lymphatic vessel endothelial hyaluronan receptor 1	Homo sapiens	113-116
18523027-5	2009	RESULTS: The MSH6 39Glu allele was associated with increased risk of colon cancer among men (Gly/Glu or Glu/Glu vs Gly/Gly, OR 1.27; 95% CI 1.04 to 1.54).	Glycine	93-96	mutS homolog 6	Homo sapiens	13-17
11395011-6	2001	Patch-clamp measurements of embryonic day 18.5 spinal cord motoneurons demonstrated an excitatory GABA and glycine action in the absence, but not in the presence, of KCC2, revealing a crucial role of KCC2 for synaptic inhibition.	Glycine	107-114	solute carrier family 12, member 5	Mus musculus	200-204
10818139-2	2000	Glycine concentration-response curves from acutely dissociated hippocampal neurons revealed a 5- and 86-fold reduction in receptor glycine affinity in mice carrying Grin1(D481N) and Grin1(K483Q) mutations, respectively, whereas receptor glutamate affinity remained unaffected.	Glycine	131-138	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	165-170
10818139-2	2000	Glycine concentration-response curves from acutely dissociated hippocampal neurons revealed a 5- and 86-fold reduction in receptor glycine affinity in mice carrying Grin1(D481N) and Grin1(K483Q) mutations, respectively, whereas receptor glutamate affinity remained unaffected.	Glycine	131-138	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	182-187
10818139-6	2000	Interestingly, in situ hybridization and Western blot analysis revealed changes in the expression levels of NMDA receptor subunits in Grin1(D481N) mice relative to wild type that may represent a compensatory response to the reduction in receptor glycine affinity.	Glycine	246-253	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	134-139
11798584-4	2001	RESULTS: In one of the three families a glycine to alanine substitution was identified in the collagenous region of the COL4A5 gene, and the mutation cosegregates with hematuria in this family.	Glycine	40-47	collagen type IV alpha 5 chain	Homo sapiens	120-126
18523027-5	2009	RESULTS: The MSH6 39Glu allele was associated with increased risk of colon cancer among men (Gly/Glu or Glu/Glu vs Gly/Gly, OR 1.27; 95% CI 1.04 to 1.54).	Glycine	115-118	mutS homolog 6	Homo sapiens	13-17
18523027-5	2009	RESULTS: The MSH6 39Glu allele was associated with increased risk of colon cancer among men (Gly/Glu or Glu/Glu vs Gly/Gly, OR 1.27; 95% CI 1.04 to 1.54).	Glycine	115-118	mutS homolog 6	Homo sapiens	13-17
11292060-0	2001	NMDA and glycine regulate the affinity of the Mg2+-block site in NR1-1a/NR2A NMDA receptor channels expressed in Xenopus oocytes.	Glycine	9-16	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	77-90
19101823-7	2009	Based on the Ufc1 and Ufm1 NMR structures, a model could be derived for the Ufc1-Ufm1 complex in which the C-terminal Gly(83) of Ufm1 may well form the expected thio-ester with Cys(116), suggesting that Ufm1-Ufc1 functions as described for other E1-E2-E3 machineries.	Glycine	118-121	ubiquitin fold modifier 1	Homo sapiens	22-26
11157057-2	2001	Substitution of lysine (K) or glycine (G) for arginine (R) at HIV-1 gag residue 264 (R264K and R264G) results in epitopes that bind to HLA-B27 poorly.	Glycine	30-37	major histocompatibility complex, class I, B	Homo sapiens	135-142
19101823-7	2009	Based on the Ufc1 and Ufm1 NMR structures, a model could be derived for the Ufc1-Ufm1 complex in which the C-terminal Gly(83) of Ufm1 may well form the expected thio-ester with Cys(116), suggesting that Ufm1-Ufc1 functions as described for other E1-E2-E3 machineries.	Glycine	118-121	ubiquitin fold modifier 1	Homo sapiens	81-85
10788434-4	2000	The alpha1(I)772-786 and alpha1(II)772-783 THPs were hydrolyzed by MMP-1 at the Gly-Ile and Gly-Leu bonds, respectively, analogous to the bonds cleaved in corresponding native collagens.	Glycine	80-83	matrix metallopeptidase 1	Homo sapiens	67-72
19101823-7	2009	Based on the Ufc1 and Ufm1 NMR structures, a model could be derived for the Ufc1-Ufm1 complex in which the C-terminal Gly(83) of Ufm1 may well form the expected thio-ester with Cys(116), suggesting that Ufm1-Ufc1 functions as described for other E1-E2-E3 machineries.	Glycine	118-121	ubiquitin fold modifier 1	Homo sapiens	81-85
10865121-4	2000	The two isoforms of the mammalian vesicular monoamine transporter, VMAT1 and VMAT2, are related to the vesicular acetylcholine transporter (VACHT), while a novel, unrelated vesicular inhibitory amino acid transporter (VIAAT), also designated vesicular GABA transporter (VGAT), is responsible for the storage of GABA, glycine or, at some synapses, both amino acids into synaptic vesicles.	Glycine	317-324	solute carrier family 18 member A3	Homo sapiens	103-138
19101823-7	2009	Based on the Ufc1 and Ufm1 NMR structures, a model could be derived for the Ufc1-Ufm1 complex in which the C-terminal Gly(83) of Ufm1 may well form the expected thio-ester with Cys(116), suggesting that Ufm1-Ufc1 functions as described for other E1-E2-E3 machineries.	Glycine	118-121	ubiquitin fold modifier 1	Homo sapiens	81-85
10865121-4	2000	The two isoforms of the mammalian vesicular monoamine transporter, VMAT1 and VMAT2, are related to the vesicular acetylcholine transporter (VACHT), while a novel, unrelated vesicular inhibitory amino acid transporter (VIAAT), also designated vesicular GABA transporter (VGAT), is responsible for the storage of GABA, glycine or, at some synapses, both amino acids into synaptic vesicles.	Glycine	317-324	solute carrier family 18 member A3	Homo sapiens	140-145
19809936-7	2009	Concentrations of glutamine (902 micromol/L), glycine (24 micromol/L) and alanine (78 micromol/L) were elevated in CSF.	Glycine	46-53	colony stimulating factor 2	Homo sapiens	115-118
10704956-0	2000	IV glycine and oral D-cycloserine effects on plasma and CSF amino acids in healthy humans.	Glycine	3-10	colony stimulating factor 2	Homo sapiens	56-59
10704956-7	2000	RESULTS: Intravenous glycine dose-dependently increased both serum and CSF glycine and serine levels.	Glycine	21-28	colony stimulating factor 2	Homo sapiens	71-74
10704956-7	2000	RESULTS: Intravenous glycine dose-dependently increased both serum and CSF glycine and serine levels.	Glycine	75-82	colony stimulating factor 2	Homo sapiens	71-74
10704956-10	2000	CONCLUSIONS: Thus, peripheral glycine administration raised CSF glycine levels without producing any clear central nervous system effects.	Glycine	30-37	colony stimulating factor 2	Homo sapiens	60-63
10704956-10	2000	CONCLUSIONS: Thus, peripheral glycine administration raised CSF glycine levels without producing any clear central nervous system effects.	Glycine	64-71	colony stimulating factor 2	Homo sapiens	60-63
11239221-3	2001	Gly-G-CSF was given subcutaneously at a dose of 10 microg per kg per day in two divided doses over 3 days and was followed by a leukapheresis (on the 4th day) 12 hours after the last dose.	Glycine	0-3	colony stimulating factor 3	Homo sapiens	4-9
11239221-9	2001	CONCLUSION: A schedule consisting of 3-day administration of gly-G-CSF followed by a single leukapheresis can be proposed and widely accepted by healthy donors, as 84 percent of them reach the target in the estimated time with a reduced drug exposure.	Glycine	61-64	colony stimulating factor 3	Homo sapiens	65-70
11152664-8	2001	The glycine corresponding to position 274 is highly conserved in other epidermal growth factor-like domains of jagged1 and in those of other proteins.	Glycine	4-11	jagged canonical Notch ligand 1	Homo sapiens	111-118
18804950-3	2009	This diagnosis was confirmed by genetic testing, which revealed a novel point mutation in the COL3A1 gene, c.2545G--&gt;C, leading to a codon encoding for arginine instead of glycine (p.Gly849Arg).	Glycine	175-182	collagen type III alpha 1 chain	Homo sapiens	94-100
10681564-4	2000	Binding interactions between Atp11p and the entire beta-subunit of F(1) or fragments of the beta-subunit were also revealed by a yeast two-hybrid screen: Atp11p bound to a region of the nucleotide-binding domain of the beta-subunit located between Gly(114) and Leu(318).	Glycine	248-251	Atp11p	Saccharomyces cerevisiae S288C	29-35
11115419-3	2001	A recent study revealed that two molecular forms of AM, i.e. a mature, active form of AM (AM-m) and an intermediate, inactive, glycine-extended form of AM (AM-Gly), circulate in human plasma.	Glycine	127-134	aminomethyltransferase	Homo sapiens	52-54
10681564-4	2000	Binding interactions between Atp11p and the entire beta-subunit of F(1) or fragments of the beta-subunit were also revealed by a yeast two-hybrid screen: Atp11p bound to a region of the nucleotide-binding domain of the beta-subunit located between Gly(114) and Leu(318).	Glycine	248-251	Atp11p	Saccharomyces cerevisiae S288C	154-160
19796526-3	2009	METHODS: MBL2 gene polymorphisms in exon 1 (MBL2 54 Gly/Asp, (A/B)), promoter (MBL2 H/L (G-550C), MBL2 Y/X (G-221C)), and 5" UTR region (MBL2 P/Q (C+4T)) were investigated using polymerase chain reaction and restriction fragment length polymorphism in 119 BD patients and 252 healthy controls.	Glycine	52-55	mannose binding lectin 2	Homo sapiens	9-13
10656678-4	2000	The resultant amino acid substitution from aspartate to glycine may have vital implication in PCNA mediated cell cycle regulation by p21(waf1/cip1).	Glycine	56-63	proliferating cell nuclear antigen	Homo sapiens	94-98
11115419-8	2001	The venous concentrations of AM-m, AM-Gly and AM-T showed similar correlations with mean pulmonary artery pressure (AM-T, r=0.67; AM-Gly, r=0.63; AM-m, r=0.59; each P&lt;0.001) and total pulmonary vascular resistance (AM-T, r=0.77; AM-Gly, r=0.70; AM-m, r=0.75; each P&lt;0.001).	Glycine	133-136	aminomethyltransferase	Homo sapiens	29-31
11090983-2	2000	In the present study, L-Ser and Gly promoted the survival of cultured rat cerebrocortical neurons in a concentration-dependent manner as revealed by Alamar blue assay and microtubule-associated protein-2 (MAP2) immunoblotting.	Glycine	32-35	microtubule-associated protein 2	Rattus norvegicus	171-203
11090983-2	2000	In the present study, L-Ser and Gly promoted the survival of cultured rat cerebrocortical neurons in a concentration-dependent manner as revealed by Alamar blue assay and microtubule-associated protein-2 (MAP2) immunoblotting.	Glycine	32-35	microtubule-associated protein 2	Rattus norvegicus	205-209
10620506-8	2000	Like these and other known lysosomal membrane proteins, endolyn contains a YXXO motif at the C-terminus of its cytoplasmic tail (where O is a bulky hydrophobic amino acid), but with no preceding glycine.	Glycine	195-202	CD164 molecule	Homo sapiens	56-63
19299230-5	2009	Genetic analysis showed a non-previously described mutation affecting a consensus splice site (IVS2-1G > C 3) in the AMT gene encoding the T protein of the glycine cleavage system.	Glycine	156-163	aminomethyltransferase	Homo sapiens	117-120
11213485-2	2000	Cytosolic thioredoxin reductase from mammalian cells is a dimeric flavin enzyme comprising a glutathione reductase-like equivalent elongated with 16 residues including the conserved carboxy-terminal sequence, Gly-Cys-SeCys-Gly, where SeCys is selenocysteine.	Glycine	209-212	thioredoxin	Homo sapiens	10-21
11213485-2	2000	Cytosolic thioredoxin reductase from mammalian cells is a dimeric flavin enzyme comprising a glutathione reductase-like equivalent elongated with 16 residues including the conserved carboxy-terminal sequence, Gly-Cys-SeCys-Gly, where SeCys is selenocysteine.	Glycine	223-226	thioredoxin	Homo sapiens	10-21
11211158-3	2000	The synthetic peptide Cys-Gly-(Arg-Gly-Asp)-Ser-Pro-Lys, containing the cell-adhesive region of fibronectin (RGD), has been grafted to the polymer substrate via the cysteine residue using a procedure recently developed in the authors laboratory.	Glycine	26-29	fibronectin 1	Rattus norvegicus	96-107
11121180-1	2000	Several recent meta-analyses appear to show a weak but significant effect of both forms of the gly/ser DRD3 polymorphism in conferring risk for schizophrenia.	Glycine	95-98	dopamine receptor D3	Homo sapiens	103-107
11209755-6	2000	The architecture of the substrate binding site of granzyme B appears to be designed to accommodate and cleave hexapeptides such as the sequence Ile-Glu-Thr-Asp-/Ser-Gly present in the activation site of pro-caspase-3, a proven physiological substrate of granzyme B.	Glycine	165-168	granzyme B	Homo sapiens	50-60
11209755-6	2000	The architecture of the substrate binding site of granzyme B appears to be designed to accommodate and cleave hexapeptides such as the sequence Ile-Glu-Thr-Asp-/Ser-Gly present in the activation site of pro-caspase-3, a proven physiological substrate of granzyme B.	Glycine	165-168	granzyme B	Homo sapiens	254-264
11237106-1	2000	Thioredoxin (TRX) is a 12 kD protein with redox-active dithiol in the active site; -Cys-Gly-Pro-Cys-.	Glycine	88-91	thioredoxin	Homo sapiens	0-11
11237106-1	2000	Thioredoxin (TRX) is a 12 kD protein with redox-active dithiol in the active site; -Cys-Gly-Pro-Cys-.	Glycine	88-91	thioredoxin	Homo sapiens	13-16
10942763-0	2000	Replacement of the distal glycine 139 transforms human heme oxygenase-1 into a peroxidase.	Glycine	26-33	heme oxygenase 1	Homo sapiens	55-71
10942763-1	2000	The human heme oxygenase-1 crystal structure suggests that Gly-139 and Gly-143 interact directly with iron-bound ligands.	Glycine	59-62	heme oxygenase 1	Homo sapiens	10-26
10942763-1	2000	The human heme oxygenase-1 crystal structure suggests that Gly-139 and Gly-143 interact directly with iron-bound ligands.	Glycine	71-74	heme oxygenase 1	Homo sapiens	10-26
10882725-7	2000	In the N-terminal region of CIS3, the amino acid Gly(45) was critical for binding to the EPOR but not to JAK2, while Leu(22) was critical for binding to JAK2.	Glycine	49-52	suppressor of cytokine signaling 3	Mus musculus	28-32
10882725-7	2000	In the N-terminal region of CIS3, the amino acid Gly(45) was critical for binding to the EPOR but not to JAK2, while Leu(22) was critical for binding to JAK2.	Glycine	49-52	erythropoietin receptor	Mus musculus	89-93
11000005-1	2000	The two hormones cholecystokinin and gastrin share the same C-terminal sequence of amino acids, namely Gly(29)-Trp(30)-Met(31)-Asp(32)-Phe(33)-NH(2).	Glycine	103-106	gastrin	Homo sapiens	37-44
10962227-7	2000	The new product was mono-SAPG-substituted insulin substituted at the B1-phenylalanine position (B1-SAPG-INS) and was selectively synthesized after protection of the A1-glycine and varepsilonB29-lysine amino acids.	Glycine	168-175	insulin	Bos taurus	42-49
10960447-0	2000	Glycine prevents apoptosis of rat sinusoidal endothelial cells caused by deprivation of vascular endothelial growth factor.	Glycine	0-7	vascular endothelial growth factor A	Rattus norvegicus	88-122
10960447-3	2000	Here, we investigated the effect of glycine on apoptosis of primary cultured rat SECs induced by vascular endothelial growth factor (VEGF) deprivation.	Glycine	36-43	vascular endothelial growth factor A	Rattus norvegicus	97-131
10960447-3	2000	Here, we investigated the effect of glycine on apoptosis of primary cultured rat SECs induced by vascular endothelial growth factor (VEGF) deprivation.	Glycine	36-43	vascular endothelial growth factor A	Rattus norvegicus	133-137
10960447-8	2000	Interestingly, this increase in TUNEL-positive cells after VEGF deprivation was prevented significantly when glycine (1-10 mmol/L) was added to the medium, the levels being around 60% of VEGF deprivation without glycine.	Glycine	109-116	vascular endothelial growth factor A	Rattus norvegicus	59-63
10960447-8	2000	Interestingly, this increase in TUNEL-positive cells after VEGF deprivation was prevented significantly when glycine (1-10 mmol/L) was added to the medium, the levels being around 60% of VEGF deprivation without glycine.	Glycine	109-116	vascular endothelial growth factor A	Rattus norvegicus	187-191
10960447-10	2000	Moreover, Bcl-2 protein levels in SECs were decreased 8 hours after VEGF deprivation, which was prevented almost completely by glycine.	Glycine	127-134	vascular endothelial growth factor A	Rattus norvegicus	68-72
10960447-11	2000	It is concluded that glycine prevents apoptosis of primary cultured SECs under VEGF deprivation.	Glycine	21-28	vascular endothelial growth factor A	Rattus norvegicus	79-83
10869363-8	2000	The results indicate that regiospecificity is controlled by the presence or absence of a three-residue insert (Ser-114, Gly-115, Ile-116) in CYP4A3 and by the residue at position 119 (CYP4A3 numbering).	Glycine	120-123	cytochrome P450, family 4, subfamily a, polypeptide 3	Rattus norvegicus	141-147
10976799-6	2000	MMP-1 (interstitial collagenase) cleaved the substrates at a single Gly-Ile bond, analogous to the cleavage site in type I collagen.	Glycine	68-71	matrix metallopeptidase 1	Homo sapiens	0-5
10976799-6	2000	MMP-1 (interstitial collagenase) cleaved the substrates at a single Gly-Ile bond, analogous to the cleavage site in type I collagen.	Glycine	68-71	matrix metallopeptidase 1	Homo sapiens	7-31
10971626-5	2000	The releasing effect of gp120 was prevented by blocking the glycine site or the ion channel of NMDA receptors, but not the glutamate recognition site; in addition, the gp120 effect was strongly inhibited by nanomolar concentrations of Zn2+ ions and by low micromolar concentrations of ifenprodil.	Glycine	60-67	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	24-29
10971626-5	2000	The releasing effect of gp120 was prevented by blocking the glycine site or the ion channel of NMDA receptors, but not the glutamate recognition site; in addition, the gp120 effect was strongly inhibited by nanomolar concentrations of Zn2+ ions and by low micromolar concentrations of ifenprodil.	Glycine	60-67	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	168-173
10971626-6	2000	It is concluded that gp120 acts as a very potent agonist at the glycine site of NMDA receptors sited on CCK- and SRIF-releasing nerve endings; the protein is able to activate the receptor channel in the absence of glutamate.	Glycine	64-71	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	21-26
10971113-2	2000	Gly m Bd 28K, a soybean allergen, was a glycoprotein with glycan moieties, which are supposed to be the Man(3)GlcNAc(2) backbone with the beta1--&gt;2 xylose and alpha1--&gt;3 fucose branches.	Glycine	0-3	adrenoceptor alpha 1D	Homo sapiens	162-168
11256583-7	2000	Several polymorphisms in the IRS genes have been identified, but only the Gly --&gt; Arg72 substitution of IRS-1, acting with environmental factors, seems to have a pathogenic role in the development of Type 2 diabetes.	Glycine	74-77	insulin receptor substrate 1	Mus musculus	107-112
10871321-7	2000	BK1-5 (Arg-Pro-Pro-Gly-Phe), the 1-to-5 amino acid fragment of bradykinin, was identified as a major stable plasma metabolite of bradykinin.	Glycine	19-22	bradykinin receptor B2	Homo sapiens	0-5
10788434-4	2000	The alpha1(I)772-786 and alpha1(II)772-783 THPs were hydrolyzed by MMP-1 at the Gly-Ile and Gly-Leu bonds, respectively, analogous to the bonds cleaved in corresponding native collagens.	Glycine	92-95	matrix metallopeptidase 1	Homo sapiens	67-72
10843189-0	2000	The Gly--&gt;Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells.	Glycine	4-7	insulin receptor substrate 1	Homo sapiens	47-75
10712613-1	2000	The conversion of L-threonine to glycine in both prokaryotes and eukaryotes takes place through a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase (EC 1.1.1103) and 2-amino-3-ketobutyrate coenzyme A ligase (KBL; EC 2.3.1.29).	Glycine	33-40	glycine C-acetyltransferase	Homo sapiens	235-238
10699990-3	2000	The role of Ki-ras activation (a G--&gt;C transversion in codon 12, arginine for glycine) in the cell cycle and apoptosis was investigated using control and permanently transfected NIH3T3 mouse fibroblasts.	Glycine	81-88	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	12-18
10686400-3	2000	Here we show that micromolar concentrations of a synthetic peptide corresponding to the V3-loop of gp120 (V3-pep) inhibited agonist responses of recombinant heteromeric rodent NMDA receptors expressed in Xenopus laevis oocytes by decreasing their apparent glycine affinity.	Glycine	256-263	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	99-104
10688364-3	2000	For example, at the R/G editing site of gluR-B, -C, and -D RNAs, ADARs change an arginine codon (AGA) to a glycine codon (IGA) so that two protein isoforms can be synthesized from a single encoded mRNA; the highly related gluR-A sequence is not edited at this site.	Glycine	107-114	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	222-228
11330044-1	2000	Glyoxylate is an immediate precursor of oxalate, but in its metabolism the conversion into glycine catalyzed by serine:pyruvate/alanine:glyoxylate aminotransferase (SPT/AGT) appears to be the main route.	Glycine	91-98	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	165-168
19158217-7	2009	SHMT-mediated conversion of glycine to serine increased from 182 +/- 7 to 205 +/- 9 micromol x kg(-1) x h(-1) (P &lt; 0.05), but serine production using a GCS-derived 1-carbon unit (93 +/- 9 vs. 91 +/- 6 micromol x kg(-1) x h(-1)) and glycine cleavage (163 +/- 11 vs. 151 +/- 8 micromol x kg(-1) x h(-1)) were not changed by vitamin B-6 restriction.	Glycine	28-35	serine hydroxymethyltransferase 1	Homo sapiens	0-4
10658641-9	2000	Thiokynurenate, a cysteine analog and an antagonist at the N-methyl-D-aspartate receptor glycine co-activatory site, was a potent activator of glutathione binding.	Glycine	89-96	glutamate ionotropic receptor NMDA type subunit 1	Sus scrofa	59-88
19158217-7	2009	SHMT-mediated conversion of glycine to serine increased from 182 +/- 7 to 205 +/- 9 micromol x kg(-1) x h(-1) (P &lt; 0.05), but serine production using a GCS-derived 1-carbon unit (93 +/- 9 vs. 91 +/- 6 micromol x kg(-1) x h(-1)) and glycine cleavage (163 +/- 11 vs. 151 +/- 8 micromol x kg(-1) x h(-1)) were not changed by vitamin B-6 restriction.	Glycine	235-242	serine hydroxymethyltransferase 1	Homo sapiens	0-4
19270429-9	2009	These results suggest the therapeutic relevance of GlyT1 inhibitors for amelioration of motor ataxia in spinocerebellar atrophy by increasing the endogenous concentration of glycine near the glycine-recognition site of the NMDA receptor.	Glycine	191-198	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	51-56
10608900-6	1999	Indispensabilities of Val(39), Ile(45), and Leu(53) indicate that an amphipathic property of alpha-helix I consisting of 14 residues of the module (Thr(44)-Gly(58)) is essential to maintain the stable catalytic surface for 8-oxo-dGTPase.	Glycine	156-159	nudix hydrolase 1	Homo sapiens	223-236
19236233-6	2009	K57 substitution with a glycine in sCD38p impaired its ability to inhibit syncytia formation in MT-2/H9(IIIB) cell cocultures and gp120 binding to CD4 in a mouse T cell line expressing human but not mouse CD4.	Glycine	24-31	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	130-135
10608809-1	1999	Glycine N-methyltransferase (EC 2.1.1.20) catalyzes the methylation of glycine by S-adenosylmethionine to form sarcosine and S-adenosylhomocysteine.	Glycine	71-78	glycine N-methyltransferase	Rattus norvegicus	0-27
18940194-1	2009	Several compounds that promote activation of the N-methyl-d-aspartate receptor (NMDAR) glycine site have been proposed as treatments for schizophrenia, but the impact of these putative antipsychotics on anxiety remains unclear.	Glycine	87-94	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	49-78
10569731-6	1999	Enzymatic activity of CD26 induced by IL-1alpha on fibroblasts was determined colorimetrically in terms of Gly-Pro hydrolysis of a synthetic chromogenic substrate, Gly-Pro p-nitroanilide.	Glycine	107-110	dipeptidyl peptidase 4	Homo sapiens	22-26
10569731-6	1999	Enzymatic activity of CD26 induced by IL-1alpha on fibroblasts was determined colorimetrically in terms of Gly-Pro hydrolysis of a synthetic chromogenic substrate, Gly-Pro p-nitroanilide.	Glycine	107-110	interleukin 1 alpha	Homo sapiens	38-47
18940194-1	2009	Several compounds that promote activation of the N-methyl-d-aspartate receptor (NMDAR) glycine site have been proposed as treatments for schizophrenia, but the impact of these putative antipsychotics on anxiety remains unclear.	Glycine	87-94	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	80-85
18940194-3	2009	In the elevated plus-maze, open field, and novel object test, homozygous Grin1(D481N) mutant mice that have a five-fold reduction in NMDAR glycine affinity demonstrated an anxiolytic-like phenotype.	Glycine	139-146	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	73-78
18940194-3	2009	In the elevated plus-maze, open field, and novel object test, homozygous Grin1(D481N) mutant mice that have a five-fold reduction in NMDAR glycine affinity demonstrated an anxiolytic-like phenotype.	Glycine	139-146	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	133-138
18940194-4	2009	In contrast, d-serine, a direct activator of the NMDAR glycine site, and ALX-5407, a glycine transporter-1 (GlyT-1) inhibitor, enhanced anxiety-like behaviors in wild-type and Grin1(D481N) mutant animals.	Glycine	55-62	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	49-54
10535747-4	1999	In contrast, an alphavbeta3 integrin-expressing cell line, SK-MEL-24, was able to adhere to OPN in an arginine-glycine-aspartic acid dependent manner.	Glycine	111-118	secreted phosphoprotein 1	Homo sapiens	92-95
18449897-2	2009	Several groups attempted to find an association between a serine-to-glycine polymorphism of the DRD3 gene (Ser9Gly) and schizophrenia; however, the results were inconsistent.	Glycine	68-75	dopamine receptor D3	Homo sapiens	96-100
10449634-1	1999	The role of adhesion molecules like osteopontin and bone sialoprotein, both containing the Arg-Gly-Asp sequence have been shown to have a role in mineral formation, whereas fibronectin (FN), another adhesive protein, was never studied during the mineralization processes.	Glycine	95-98	secreted phosphoprotein 1	Homo sapiens	36-47
19363270-7	2009	Among the DAT with BPSD, however, a significant association was observed between the presence of the DRD3 glycine allele and paranoid and delusional ideation, regardless of ApoE epsilon4.	Glycine	106-113	dopamine receptor D3	Homo sapiens	101-105
19117914-1	2009	Activation of the N-methyl-D-aspartate receptor (NMDAR) glycine site has been shown to accelerate adaptive forms of learning that may benefit psychopathologies involving cognitive and perseverative disturbances.	Glycine	56-63	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	18-47
10543877-9	1999	The SP pseudopeptides showed considerably lower affinities (IC(50) &gt; 1 microM) for the NK(1) receptor than SP itself (IC(50) = 1.5 nM) indicating that the Phe-Gly replacements prevent the pseudopeptides from adopting bioactive conformations.	Glycine	162-165	tachykinin receptor 1	Homo sapiens	90-104
19117914-1	2009	Activation of the N-methyl-D-aspartate receptor (NMDAR) glycine site has been shown to accelerate adaptive forms of learning that may benefit psychopathologies involving cognitive and perseverative disturbances.	Glycine	56-63	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	49-54
18771702-0	2008	Glycine-extended gastrin stimulates proliferation via JAK2- and Akt-dependent NF-kappaB activation in Barrett"s oesophageal adenocarcinoma cells.	Glycine	0-7	gastrin	Homo sapiens	17-24
10479737-0	1999	Design, synthesis, and conformational studies of the hGM-CSF derived peptide (13-27)-Gly-(75-87).	Glycine	85-88	colony stimulating factor 2	Homo sapiens	53-60
10479737-1	1999	An analogue of the human granulocyte-macrophage colony-stimulating factor (hGM-CSF), hGM-CSF(13-27)-Gly-(75-87) was synthesized by solid phase methodology.	Glycine	100-103	colony stimulating factor 2	Homo sapiens	25-73
10479737-1	1999	An analogue of the human granulocyte-macrophage colony-stimulating factor (hGM-CSF), hGM-CSF(13-27)-Gly-(75-87) was synthesized by solid phase methodology.	Glycine	100-103	colony stimulating factor 2	Homo sapiens	75-82
18771702-1	2008	Glycine-extended gastrin (G-Gly) is a mitogen for several gastrointestinal tissues although the mechanisms responsible are ill-defined and it is unknown if G-Gly can influence signalling in Barrett"s oesophagus.	Glycine	0-7	gastrin	Homo sapiens	17-24
10479737-1	1999	An analogue of the human granulocyte-macrophage colony-stimulating factor (hGM-CSF), hGM-CSF(13-27)-Gly-(75-87) was synthesized by solid phase methodology.	Glycine	100-103	colony stimulating factor 2	Homo sapiens	85-92
18852262-4	2008	This difference is due to an extra Gly residue found in the FMN binding loop in NOS compared with P450BM3.	Glycine	35-38	formin 1	Homo sapiens	60-63
18852262-5	2008	We have deleted residue Gly-810 from the FMN binding loop in neuronal NOS (nNOS) to give Delta G810 so that the shorter binding loop mimics that in cytochrome P450BM3.	Glycine	24-27	formin 1	Homo sapiens	41-44
10497166-0	1999	Importance of the P2 glycine of antithrombin in target proteinase specificity, heparin activation, and the efficiency of proteinase trapping as revealed by a P2 Gly --&gt; Pro mutation.	Glycine	21-28	serpin family C member 1	Homo sapiens	32-44
10497166-0	1999	Importance of the P2 glycine of antithrombin in target proteinase specificity, heparin activation, and the efficiency of proteinase trapping as revealed by a P2 Gly --&gt; Pro mutation.	Glycine	161-164	serpin family C member 1	Homo sapiens	32-44
18835253-4	2008	In particular, the roles of Trp60 for MHC-I assembly and beta2m stability have been highlighted by showing that the beta2m Trp60--&gt;Gly mutant is more stable and less prone to aggregation than the wild type protein.	Glycine	134-137	beta-2-microglobulin	Homo sapiens	116-122
10497166-2	1999	To test whether the factor Xa specificity of allosterically activated antithrombin is encoded in the serpin reactive center loop, we mutated the factor Xa-preferred P2 Gly to the thrombin-preferred P2 Pro.	Glycine	168-171	serpin family C member 1	Homo sapiens	70-82
10571879-4	1999	The methylenetetra- hydrofolate (CH2-THF) produced during this reaction did not equilibrate with the overall CH2-THF pool, but was almost totally recycled by the mitochondrial serine hydroxymethyltransferase (SHMT) for the synthesis of one serine from a second molecule of glycine.	Glycine	273-280	serine hydroxymethyltransferase 1	Homo sapiens	209-213
10571879-8	1999	However, the largest part (about two-thirds) involved serine-to-glycine conversion by cytosolic SHMT, then glycine oxidation by GDC.	Glycine	64-71	serine hydroxymethyltransferase 1	Homo sapiens	96-100
10571879-11	1999	The glycine formed during this process is rapidly oxidized by the mitochondrial GDC-SHMT enzymatic system, which is therefore required in all plant tissues.	Glycine	4-11	serine hydroxymethyltransferase 1	Homo sapiens	84-88
18930730-4	2008	Our data demonstrate that glycine treatment in lean mice suppressed TNF-alpha transcriptional expression in fat tissue, and serum protein levels of IL-6 were suppressed, while adiponectin levels were increased.	Glycine	26-33	adiponectin, C1Q and collagen domain containing	Mus musculus	176-187
10485845-4	1999	Protein-protein interaction assays suggest that Gro and Rpd3 form a complex in vivo and that they interact directly via the glycine/proline rich (GP) domain in Gro.	Glycine	124-131	Histone deacetylase 1	Drosophila melanogaster	56-60
18930730-10	2008	In conclusion, our findings suggest that glycine suppresses the pro-inflammatory cytokines production and increases adiponectin secretion in vivo through the activation of PPAR-gamma.	Glycine	41-48	adiponectin, C1Q and collagen domain containing	Mus musculus	116-127
10605009-0	2000	Glycine inhibits growth of T lymphocytes by an IL-2-independent mechanism.	Glycine	0-7	interleukin 2	Rattus norvegicus	47-51
18815213-0	2008	Inhibitors of GlyT1 affect glycine transport via discrete binding sites.	Glycine	27-34	solute carrier family 6 member 9 L homeolog	Xenopus laevis	14-19
10605009-8	2000	Surprisingly, glycine had no effect on IL-2 production in the mixed lymphocyte culture; therefore, the effect of glycine on IL-2-dependent proliferation was tested.	Glycine	113-120	interleukin 2	Rattus norvegicus	124-128
10605009-9	2000	Glycine and rapamycin caused dose-dependent decreases in IL-2-stimulated growth of Ctll-2 cells to about 60% and 40%, respectively, of control.	Glycine	0-7	interleukin 2	Mus musculus	57-61
10605009-10	2000	Moreover, glycine also inhibited the IL-2-stimulated growth of rat splenic lymphocytes.	Glycine	10-17	interleukin 2	Rattus norvegicus	37-41
10605009-11	2000	It is concluded that glycine blunts proliferation in an IL-2-independent manner.	Glycine	21-28	interleukin 2	Rattus norvegicus	56-60
10430617-2	1999	The most prevalent IRS-1 variant, a Gly--&gt;Arg change at the codon 972, has been reported to be increased in prevalence among patients with type 2 diabetes.	Glycine	36-39	insulin receptor substrate 1	Homo sapiens	19-24
18815213-1	2008	In the forebrain, synaptic glycine concentrations are regulated through the glycine transporter GlyT1.	Glycine	27-34	solute carrier family 6 member 9 L homeolog	Xenopus laevis	96-101
10395903-7	1999	The conserved mammalian cell-attachment signal Arg-Gly-Asp is absent in the caiman DMP1.	Glycine	51-54	dentin matrix acidic phosphoprotein 1	Homo sapiens	83-87
11202225-7	2000	The resultant IGF-I protein appears to have a dual role, first as an endogenous neurotropic and anti-apoptotic agent acting directly on stressed cells, and second as a prohormone for generation of the N-terminal tripeptide of IGF-I, glycine-proline-glutamate (GPE), and the resulting des-N-(1-3)-IGF-I, both of which have specific neuroprotective properties.	Glycine	233-240	insulin-like growth factor 1	Rattus norvegicus	14-19
18815213-2	2008	Because glycine is a coagonist of the N-methyl-D-aspartate (NMDA) receptor (NMDAR), which has been implicated in schizophrenia, inhibition of GlyT1 is thought to provide an option for the treatment of schizophrenia.	Glycine	8-15	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	38-74
10377064-1	1999	Ubiquitin cross-reactive protein (UCRP) is a 17-kDa protein that shows cross-reactivity with ubiquitin antisera and retains the carboxyl-terminal Leu-Arg-Gly-Gly amino acid sequence of ubiquitin that ligates to, and directs degradation of, cytosolic proteins.	Glycine	154-157	ISG15 ubiquitin like modifier	Bos taurus	0-32
10377064-1	1999	Ubiquitin cross-reactive protein (UCRP) is a 17-kDa protein that shows cross-reactivity with ubiquitin antisera and retains the carboxyl-terminal Leu-Arg-Gly-Gly amino acid sequence of ubiquitin that ligates to, and directs degradation of, cytosolic proteins.	Glycine	154-157	ISG15 ubiquitin like modifier	Bos taurus	34-38
18815213-2	2008	Because glycine is a coagonist of the N-methyl-D-aspartate (NMDA) receptor (NMDAR), which has been implicated in schizophrenia, inhibition of GlyT1 is thought to provide an option for the treatment of schizophrenia.	Glycine	8-15	solute carrier family 6 member 9 L homeolog	Xenopus laevis	142-147
10377064-1	1999	Ubiquitin cross-reactive protein (UCRP) is a 17-kDa protein that shows cross-reactivity with ubiquitin antisera and retains the carboxyl-terminal Leu-Arg-Gly-Gly amino acid sequence of ubiquitin that ligates to, and directs degradation of, cytosolic proteins.	Glycine	158-161	ISG15 ubiquitin like modifier	Bos taurus	0-32
18815213-9	2008	In GlyT1-expressing membranes, the binding of the novel radioligand [(3)H]N-methyl-SSR504734 to a single site on GlyT1 was competitively displaced by glycine and SSR504734 but noncompetitively by sarcosine-based compounds.	Glycine	150-157	solute carrier family 6 member 9 L homeolog	Xenopus laevis	113-118
10377064-1	1999	Ubiquitin cross-reactive protein (UCRP) is a 17-kDa protein that shows cross-reactivity with ubiquitin antisera and retains the carboxyl-terminal Leu-Arg-Gly-Gly amino acid sequence of ubiquitin that ligates to, and directs degradation of, cytosolic proteins.	Glycine	158-161	ISG15 ubiquitin like modifier	Bos taurus	34-38
18805436-9	2008	It was proposed that: a) blockade of GlyT1 mediated reuptake of glycine, or b) inhibition of D-amino Acid Oxidase, or Asc-1 will elevate brain glycine, and D-serine to upregulate NMDA receptor functions via glycine and D-serine co-agonistic allosteric modulation of the GlyB sites on the NMDA receptor.	Glycine	143-150	D-amino acid oxidase	Homo sapiens	93-113
11202225-7	2000	The resultant IGF-I protein appears to have a dual role, first as an endogenous neurotropic and anti-apoptotic agent acting directly on stressed cells, and second as a prohormone for generation of the N-terminal tripeptide of IGF-I, glycine-proline-glutamate (GPE), and the resulting des-N-(1-3)-IGF-I, both of which have specific neuroprotective properties.	Glycine	233-240	insulin-like growth factor 1	Rattus norvegicus	226-231
10403934-6	1999	Moreover the levels of anti-BPI in the IgG fraction could be augmented by preincubation with glycine pH 2.5 for 30 min.	Glycine	93-100	bactericidal permeability increasing protein	Homo sapiens	28-31
11202225-7	2000	The resultant IGF-I protein appears to have a dual role, first as an endogenous neurotropic and anti-apoptotic agent acting directly on stressed cells, and second as a prohormone for generation of the N-terminal tripeptide of IGF-I, glycine-proline-glutamate (GPE), and the resulting des-N-(1-3)-IGF-I, both of which have specific neuroprotective properties.	Glycine	233-240	insulin-like growth factor 1	Rattus norvegicus	226-231
18793697-2	2008	Since the concentration of glycine in the synaptic cleft is controlled by specialized proteins, the glycine transporters GlyT1 and GlyT2, manipulation of this system might have significant effects on nociception.	Glycine	27-34	solute carrier family 6 member 5	Rattus norvegicus	131-136
10607386-2	2000	Gephyrin is a synaptic protein that is required for clustering of glycine and GABAA receptors.	Glycine	66-73	gephyrin	Homo sapiens	0-8
10381765-1	1999	We examined the effect of ondansetron, an antagonist of type 3 serotonin receptors, on the whole cell response of freshly isolated hippocampal CA1 pyramidal neurons of neonatal and "mature" rats to glycine using the gramicidin perforated patch technique.	Glycine	198-205	carbonic anhydrase 1	Rattus norvegicus	143-146
18808143-6	2008	These peptides were synthesized to confirm their ACE-inhibitory activities; this showed that peptides with a Gly-Ala-Hyp-Gly-Leu-Hyp-Gly-Pro sequence had the highest activity (IC 50 = 29 microM).	Glycine	109-112	angiotensin I converting enzyme	Gallus gallus	49-52
10404594-8	1999	CONCLUSIONS: The potency of staurosporine against Lck derives in part from an induced movement of the glycine-rich loop of the enzyme upon binding of this ligand, which maximizes the van der Waals interactions present in the complex.	Glycine	102-109	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	50-53
10423700-7	1999	This corresponded to the site of amino acid substitution (glycine to asparate) at position 169 in predicted NRAMP which had been reported.	Glycine	58-65	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	Mus musculus	108-113
10658629-2	2000	The responses to glycine, like those to acetylcholine, are blocked by administration of a muscarinic receptor antagonist and prolonged by administration of an acetylcholinesterase inhibitor.	Glycine	17-24	acetylcholinesterase	Rattus norvegicus	159-179
18808143-6	2008	These peptides were synthesized to confirm their ACE-inhibitory activities; this showed that peptides with a Gly-Ala-Hyp-Gly-Leu-Hyp-Gly-Pro sequence had the highest activity (IC 50 = 29 microM).	Glycine	121-124	angiotensin I converting enzyme	Gallus gallus	49-52
17433503-3	2008	There is considerable preclinical evidence for the importance of glycine recognition sites (GlyRS) of N-methyl-D-aspartate (NMDA) receptors in the regulation of anxiety behaviors.	Glycine	65-72	glycyl-tRNA synthetase 1	Homo sapiens	92-97
10639739-1	1999	Peptidylglycine alpha-amidating monooxygenase (PAM), which catalazyes the two-step formation of bioactive alpha-amidated peptides from their glycine-extended precursors, has been found in H9c2 myoblasts.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	47-50
10523664-0	1999	The glycine-phenylalanine-rich region determines the specificity of the yeast Hsp40 Sis1.	Glycine	4-11	type II HSP40 co-chaperone SIS1	Saccharomyces cerevisiae S288C	84-88
10523664-4	1999	A C-terminal truncation of Sis1, removing 231 amino acids but retaining the N-terminal 121 amino acids encompassing the J domain and the glycine-phenylalanine-rich (G-F) region, was able to rescue the inviability of a Deltasis1 strain.	Glycine	137-144	type II HSP40 co-chaperone SIS1	Saccharomyces cerevisiae S288C	27-31
10215667-4	1999	Felbamate reduced NMDA- and glycine-induced currents most effectively at NMDA receptors composed of NR1 and NR2B subunits (IC50 = 0.93 mM), followed by NR1-2C (2.02 mM) and NR1-2A (8.56 mM) receptors.	Glycine	28-35	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	100-103
10215667-4	1999	Felbamate reduced NMDA- and glycine-induced currents most effectively at NMDA receptors composed of NR1 and NR2B subunits (IC50 = 0.93 mM), followed by NR1-2C (2.02 mM) and NR1-2A (8.56 mM) receptors.	Glycine	28-35	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	108-112
10215667-5	1999	The NR1-2B-selective interaction was noncompetitive with respect to the coagonists NMDA and glycine and was not dependent on voltage.	Glycine	92-99	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	4-7
18815261-4	2008	Here, we establish that GlyT2-mediated uptake is directly coupled to the accumulation of glycine into recycling synaptic vesicles using cultured spinal cord neurons derived from GlyT2-enhanced green fluorescent protein transgenic mice.	Glycine	89-96	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	24-29
10365754-9	1999	This suggests that the triple-helical Gly-Pro-Hyp repeat in CRP and analogous sequences in fibrillar collagen stimulate the procoagulant response of adherent platelets by acting as ligands for GpVI.	Glycine	38-41	glycoprotein VI platelet	Homo sapiens	193-197
10510301-15	1999	In wild-type BuChE both residues function like valves, whereas in the mutant enzymes the water network is slack, and residues Gly-70 and Asp-197 function like check valves, i.e. forced penetration of water into the gorge is not easily achieved, thereby facilitating the release of water.	Glycine	126-129	butyrylcholinesterase	Homo sapiens	13-18
18815261-6	2008	We show that GlyT2 inhibition induces a switch from a predominantly glycine to a predominantly GABA phenotype.	Glycine	68-75	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	13-18
10187828-6	1999	By reverse transcriptase-polymerase chain reaction and sequence analysis, G to A point mutations were identified in CEM/Mtx-1 transcripts at positions 130 (P1; changes glycine 44 --&gt; arginine) and 380 (P2; changes serine 127 --&gt; asparagine).	Glycine	168-175	metaxin 1	Homo sapiens	120-125
18351593-6	2008	Subjects with the DRD3 Gly/Gly genotype showed significantly poorer performance than Ser/Ser subjects in executive functioning tasks (P = 0.002; adjusted R(2) = 0.031), with no significant differences in the other cognitive paradigms.	Glycine	23-26	dopamine receptor D3	Homo sapiens	18-22
10198322-9	1999	These data demonstrate that 1) amidated secretin and secretin-Gly are not separable under some chromatographic conditions, 2) current RIA may not detect bioactive COOH-terminally extended forms of secretin in tissue extracts or blood, and 3) the secretin receptor mediating stimulation of pancreatic secretion recognizes both amidated and COOH-terminally extended secretins.	Glycine	62-65	SCT	Canis lupus familiaris	53-61
10517800-14	1999	Systematic mutation of extracellular histidine residues in the GlyR alpha1 subunit revealed that mutations H107A or H109A completely abolished inhibition of glycine-gated currents by Zn2+.	Glycine	157-164	glycine receptor alpha 1	Homo sapiens	63-74
10198322-9	1999	These data demonstrate that 1) amidated secretin and secretin-Gly are not separable under some chromatographic conditions, 2) current RIA may not detect bioactive COOH-terminally extended forms of secretin in tissue extracts or blood, and 3) the secretin receptor mediating stimulation of pancreatic secretion recognizes both amidated and COOH-terminally extended secretins.	Glycine	62-65	SCT	Canis lupus familiaris	53-61
18351593-6	2008	Subjects with the DRD3 Gly/Gly genotype showed significantly poorer performance than Ser/Ser subjects in executive functioning tasks (P = 0.002; adjusted R(2) = 0.031), with no significant differences in the other cognitive paradigms.	Glycine	27-30	dopamine receptor D3	Homo sapiens	18-22
18698233-2	2008	Two relatively common variants of the TLR4 gene are present, resulting in changes from aspartic acid (D) to glycine (G) at residue 299 and from threonine (T) to isoleucine (I) at residue 399, respectively.	Glycine	108-115	toll like receptor 4	Homo sapiens	38-42
10051546-7	1999	The serine residue, unique to the CB2 receptor, was then mutated to glycine in the K109A mutant.	Glycine	68-75	cannabinoid receptor 2	Homo sapiens	34-37
18642843-3	2008	The p34 protein, originally characterized to be p34 as an oil-body associated protein in soybean, has been identified as one of the major allergenic proteins and named Gly m Bd 30K.	Glycine	168-171	P34 probable thiol protease	Glycine max	4-7
10199602-8	1999	Compared to the vehicle treatment, glycine-proline-glutamate (n=19) treatment reduced the extent of cortical damage and neuronal loss in the CA1-2 subregions of the hippocampus (P&lt;0.05).	Glycine	35-42	carbonic anhydrase 1	Rattus norvegicus	141-144
18642843-3	2008	The p34 protein, originally characterized to be p34 as an oil-body associated protein in soybean, has been identified as one of the major allergenic proteins and named Gly m Bd 30K.	Glycine	168-171	P34 probable thiol protease	Glycine max	48-51
10226523-1	1999	BACKGROUND: Glycine-extended progastrin (G-17-Gly), the immediate biosynthetic precursor to gastrin (G-17), stimulates growth of some gastrointestinal cancers in vitro.	Glycine	12-19	gastrin	Homo sapiens	32-39
18455219-3	2008	Complementary interaction with inhibitory neurotransmission mediated by GABA(A) receptors, and upstream control of the excitability of NMDARs by glycine availability can greatly influence the efficacy of NMDAR mediated neuroplasticity, and thereby exert significant effects on cognition.	Glycine	145-152	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	135-140
9892210-4	1999	These CD44 variants bind to both the amino- and COOH-terminal portions of OPN independently of the arginine-glycine-aspartic acid sequence, suggesting that multiple domains on OPN can be bound by the CD44 variants.	Glycine	108-115	secreted phosphoprotein 1	Homo sapiens	74-77
18491921-7	2008	After adenylation, persulfurated Uba4 was able to form a thiocarboxylate group at the C-terminal glycine of either Urm1 or MOCS2A.	Glycine	97-104	molybdenum cofactor synthesis 3	Homo sapiens	33-37
9858599-1	1999	Genes encoding the Phe-Gly (FG) repeat-containing nucleoporins NUP98 and CAN/NUP214 are at the breakpoints of several chromosomal translocations associated with human acute myeloid leukemia (AML), but their role in oncogenesis is unclear.	Glycine	23-26	nucleoporin 214	Homo sapiens	73-83
18481852-4	2008	In this article, we report the design of a novel model system based upon collagen-like heterotrimers that can mimic the glycine mutations present in either the alpha1 or alpha2 chains of type I collagen.	Glycine	120-127	adrenoceptor alpha 1D	Homo sapiens	160-176
9891840-0	1998	The carboxyl-terminal fragment of osteopontin suppresses arginine-glycine-asparatic acid-dependent cell adhesion.	Glycine	66-73	secreted phosphoprotein 1	Homo sapiens	34-45
18395224-5	2008	The Trp60--&gt;Gly mutation has a threefold effect: it stabilizes beta(2)m, inhibits beta(2)m amyloidogenic propensity and weakens the interaction with the class I major histocompatibility complex heavy chain.	Glycine	15-18	beta-2-microglobulin	Homo sapiens	66-74
9804777-2	1998	BNC1 channels are transiently activated by extracellular protons and are constitutively activated by insertion of large residues, such as valine, in place of Gly-430; residue 430 is a site where analogous mutations in some Caenorhabditis elegans family members cause a swelling neurodegeneration.	Glycine	158-161	BasoNuClin-1 zinc finger protein homolog	Caenorhabditis elegans	0-4
9817840-7	1998	The NK1 kringle domain is homologous to kringle 4 from plasminogen, except that the lysine-binding pocket is altered by the insertion of a glycine residue.	Glycine	139-146	tachykinin receptor 1	Homo sapiens	4-7
9858782-0	1998	Exposure of the cryptic Arg-Gly-Asp sequence in thrombospondin-1 by protein disulfide isomerase.	Glycine	28-31	thrombospondin 1	Bos taurus	48-64
18395224-5	2008	The Trp60--&gt;Gly mutation has a threefold effect: it stabilizes beta(2)m, inhibits beta(2)m amyloidogenic propensity and weakens the interaction with the class I major histocompatibility complex heavy chain.	Glycine	15-18	beta-2-microglobulin	Homo sapiens	85-93
9858782-3	1998	This interaction is mediated via a cryptic Arg-Gly-Asp sequence in the C-terminal Ca2+-binding region of thrombospondin-1.	Glycine	47-50	thrombospondin 1	Bos taurus	105-121
9858782-5	1998	Limited reduction of thrombospondin-1 by dithiothreitol exposes the Arg-Gly-Asp sequence which can bind to the alphav beta3 integrin receptor and support endothelial cell spreading (X.	Glycine	72-75	thrombospondin 1	Bos taurus	21-37
9858782-13	1998	Treatment of thrombospondin-1 with purified protein disulfide isomerase enhanced adhesion of endothelial cells to thrombospondin-1 in an Arg-Gly-Asp-dependent manner through the alphav beta3 integrin receptor and supported cell spreading.	Glycine	141-144	thrombospondin 1	Bos taurus	13-29
9858782-13	1998	Treatment of thrombospondin-1 with purified protein disulfide isomerase enhanced adhesion of endothelial cells to thrombospondin-1 in an Arg-Gly-Asp-dependent manner through the alphav beta3 integrin receptor and supported cell spreading.	Glycine	141-144	thrombospondin 1	Bos taurus	114-130
9858782-15	1998	These results suggest that endothelial cell derived protein disulfide isomerase may regulate Arg-Gly-Asp-dependent binding of thrombospondin-1.	Glycine	97-100	thrombospondin 1	Bos taurus	126-142
18395224-6	2008	On the contrary, Trp95 is buried in the beta(2)m core; the Trp95--&gt;Gly mutation destabilizes the protein, which is unfolded in solution, yielding nonfibrillar beta(2)m aggregates.	Glycine	70-73	beta-2-microglobulin	Homo sapiens	40-48
18395224-6	2008	On the contrary, Trp95 is buried in the beta(2)m core; the Trp95--&gt;Gly mutation destabilizes the protein, which is unfolded in solution, yielding nonfibrillar beta(2)m aggregates.	Glycine	70-73	beta-2-microglobulin	Homo sapiens	162-170
18431130-10	2008	CONCLUSIONS: An increase in endogenous glycine via glycine transporter 1 blockade not only results in a net inhibitory influence on pain transmission at the spinal level but also supraspinally relieves decreased synaptic efficacy presumably related to cognitive disturbance often described in patients with chronic pain.	Glycine	39-46	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	51-72
9839942-5	1998	The rate of reaction of H2O2 with the wild-type Mb decreased 8-9-fold on mutation of the distal histidine to glycine ([Gly64]Mb).	Glycine	109-116	myoglobin	Homo sapiens	48-50
9839942-5	1998	The rate of reaction of H2O2 with the wild-type Mb decreased 8-9-fold on mutation of the distal histidine to glycine ([Gly64]Mb).	Glycine	109-116	myoglobin	Homo sapiens	125-127
9814482-3	1998	These two additional C18 conversions can be catalyzed by CYP11B1 if serine-288 and valine-320 are replaced by the corresponding CYP11B2 residues, glycine and alanine.	Glycine	146-153	cytochrome P450 family 11 subfamily B member 2	Homo sapiens	128-135
19238787-3	2008	This novel "basalopathy" is caused by glycine mutations in COL4A1 exons 24 and 25.	Glycine	38-45	collagen type IV alpha 1 chain	Homo sapiens	59-65
9798949-3	1998	GLYT2 transports glycine with higher apparent affinity than GLYT1b and is not inhibited by any assayed compound, as deduced by glycine transport assays and electrophysiological recordings.	Glycine	17-24	solute carrier family 6 member 5	Rattus norvegicus	0-5
18006876-0	2008	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	Glycine	4-7	fibrillin 1	Homo sapiens	34-53
9798949-3	1998	GLYT2 transports glycine with higher apparent affinity than GLYT1b and is not inhibited by any assayed compound, as deduced by glycine transport assays and electrophysiological recordings.	Glycine	127-134	solute carrier family 6 member 5	Rattus norvegicus	0-5
9798949-8	1998	GLYT2 exhibits more voltage dependence in both its glycine-evoked current and its capacitive currents recorded in the absence of substrate.	Glycine	51-58	solute carrier family 6 member 5	Rattus norvegicus	0-5
18179361-4	2008	Human thioredoxin 1 (TRX1) is a redox-active protein of approximately 12 kDa that contains a (32)Cys-Gly-Pro-(35)Cys sequence necessary for its activity.	Glycine	101-104	thioredoxin	Homo sapiens	6-19
9734600-11	1998	In diabetic rats given C-peptide, this reduced the initial glomerular hyperfiltration prior to glycine infusion.	Glycine	95-102	insulin 2	Rattus norvegicus	23-32
18179361-4	2008	Human thioredoxin 1 (TRX1) is a redox-active protein of approximately 12 kDa that contains a (32)Cys-Gly-Pro-(35)Cys sequence necessary for its activity.	Glycine	101-104	thioredoxin	Homo sapiens	21-25
9679761-6	1998	Both progastrin and glycine-extended gastrin-17 were produced and secreted by the tumour cell lines; however, carboxy amidated gastrin was not detected by radioimmunoassay.	Glycine	20-27	gastrin	Homo sapiens	37-44
18946534-5	2008	Recent studies of the Na(+)/Cl(-)-dependent glycine transporters GlyT1 and GlyT2 using mouse knockout models and human genetics have revealed that mutations in GlyT2 are a second major cause of hyperekplexia, while the phenotype of the GlyT1 knockout mouse resembles a devastating neurological disorder known as glycine encephalopathy (OMIM 605899).	Glycine	44-51	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	65-70
9722928-2	1998	The mature peptide has nine conserved cysteines and a conserved proline (position 36) and glycine (position 46), all characteristics of TGF-beta superfamily molecules.	Glycine	90-97	transforming growth factor beta-1 proprotein	Oncorhynchus mykiss	136-144
18946534-5	2008	Recent studies of the Na(+)/Cl(-)-dependent glycine transporters GlyT1 and GlyT2 using mouse knockout models and human genetics have revealed that mutations in GlyT2 are a second major cause of hyperekplexia, while the phenotype of the GlyT1 knockout mouse resembles a devastating neurological disorder known as glycine encephalopathy (OMIM 605899).	Glycine	44-51	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	75-80
18334018-3	2008	RESULTS: In this contribution, a method for purifying soybean (Glycine max) protein P34 (also called Gly m Bd 30 K or Gly m 1) using hydrophobic interaction chromatography is presented.	Glycine	63-66	P34 probable thiol protease	Glycine max	84-87
9639282-7	1998	[3H]D-Ala2,N-Me-Phe4,Gly-ol5-enkephalin binding to mu opioid receptors was significantly higher in the globus pallidus, amygdala, thalamus, hypothalamus, hippocampus, substantia nigra, ventral tegmental area, central gray, and interpeduncular nucleus of the naltrexone-treated rats.	Glycine	21-24	proenkephalin	Rattus norvegicus	29-39
18334018-3	2008	RESULTS: In this contribution, a method for purifying soybean (Glycine max) protein P34 (also called Gly m Bd 30 K or Gly m 1) using hydrophobic interaction chromatography is presented.	Glycine	101-104	P34 probable thiol protease	Glycine max	84-87
18310296-8	2008	Also other residues of gastrin-17, notably glycine-2 for the rat CCK2 receptor and glutamic acid 8-10 and tyrosine-12 for the human receptor, were found to be important, although to a lesser extent.	Glycine	43-50	gastrin	Homo sapiens	23-30
9749924-0	1998	Effects of the length of a glycine linker connecting the N-and C-termini of a circularly permuted dihydrofolate reductase.	Glycine	27-34	Dihydrofolate reductase	Escherichia coli	98-121
9703961-0	1998	Prohormone convertase 1 (PC1) when expressed with pro cholecystokinin (pro CCK) in L cells performs three endoproteolytic cleavages which are observed in rat brain and in CCK-expressing endocrine cells in culture, including the production of glycine and arginine extended CCK8.	Glycine	242-249	proprotein convertase subtilisin/kexin type 1	Homo sapiens	0-23
9703961-0	1998	Prohormone convertase 1 (PC1) when expressed with pro cholecystokinin (pro CCK) in L cells performs three endoproteolytic cleavages which are observed in rat brain and in CCK-expressing endocrine cells in culture, including the production of glycine and arginine extended CCK8.	Glycine	242-249	proprotein convertase subtilisin/kexin type 1	Homo sapiens	25-28
9703961-3	1998	PC1 also generated a peptide which after carboxypeptidase B treatment, was detected with an antiserum specific for CCK Gly.	Glycine	119-122	proprotein convertase subtilisin/kexin type 1	Homo sapiens	0-3
10555563-5	1999	Replacement of extracellular Na+ by choline and application of the specific glycine transporter GLYT1 inhibitor, sarcosine, lengthened tau(decay) of I(gly), but did not change the decay time constants of e-IPSCs.	Glycine	76-79	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	96-101
20641396-16	2004	The peptide GHPGGPQKC was found to be a cathepsin K (CatK) substrate and is cleaved between Gly (G) and Gly (G) residues (12).	Glycine	92-95	cathepsin K	Homo sapiens	40-51
9665852-13	1998	Finally, an invariant glycine shared by both PDF and metzincins enables us to extend the conserved motif from HEXXH to HEXXHXXG.	Glycine	22-29	peptide deformylase, mitochondrial	Homo sapiens	45-48
20641396-16	2004	The peptide GHPGGPQKC was found to be a cathepsin K (CatK) substrate and is cleaved between Gly (G) and Gly (G) residues (12).	Glycine	92-95	cathepsin K	Homo sapiens	53-57
20641396-16	2004	The peptide GHPGGPQKC was found to be a cathepsin K (CatK) substrate and is cleaved between Gly (G) and Gly (G) residues (12).	Glycine	104-107	cathepsin K	Homo sapiens	40-51
20641396-16	2004	The peptide GHPGGPQKC was found to be a cathepsin K (CatK) substrate and is cleaved between Gly (G) and Gly (G) residues (12).	Glycine	104-107	cathepsin K	Homo sapiens	53-57
9720361-3	1998	Both Retina HSP 60 and Yersinia HSP 60 showed an enriched content of glycine of approximately 60 to 80%.	Glycine	69-76	heat shock protein family D (Hsp60) member 1	Rattus norvegicus	12-18
10556563-8	1999	The other two cleavage sites in alpha(2)M by lebetase are Gly(679)-Leu(680) and His(694)-Ala(695).	Glycine	58-61	alpha-2-macroglobulin	Homo sapiens	32-41
9720361-3	1998	Both Retina HSP 60 and Yersinia HSP 60 showed an enriched content of glycine of approximately 60 to 80%.	Glycine	69-76	heat shock protein family D (Hsp60) member 1	Rattus norvegicus	32-38
20641396-20	2004	The NIR fluorescence signal will increase when the Gly-Gly bond is cleaved by CatK, releasing Cy5.5-containing fragments.	Glycine	51-54	cathepsin K	Homo sapiens	78-82
20641396-20	2004	The NIR fluorescence signal will increase when the Gly-Gly bond is cleaved by CatK, releasing Cy5.5-containing fragments.	Glycine	55-58	cathepsin K	Homo sapiens	78-82
18408221-4	2008	Firstly, amino acid residues Lys-835 and Arg-894 of maize PEPC, which correspond to Lys-773 and Arg-832 of Escherichia coli PEPC, respectively, were replaced by Gly, since they had been shown to be involved in the binding of allosteric inhibitors, malate or aspartate, by our X-ray crystallographic analysis of E. coli PEPC.	Glycine	161-164	MLO-like protein 4	Zea mays	58-62
9632659-1	1998	Many proteins contain so-called epidermal growth factor (EGF)-like domains that share the characteristic spacing of cysteines and glycines with members of the EGF family.	Glycine	130-138	epidermal growth factor	Homo sapiens	32-55
9632659-1	1998	Many proteins contain so-called epidermal growth factor (EGF)-like domains that share the characteristic spacing of cysteines and glycines with members of the EGF family.	Glycine	130-138	epidermal growth factor	Homo sapiens	57-60
10428078-3	1999	Glycine currents were inhibited by atropine in an apparently competitive manner and with considerable selectivity of the tropeines for alpha2 versus alpha1 subunits.	Glycine	0-7	adrenoceptor alpha 1D	Homo sapiens	149-155
18408221-4	2008	Firstly, amino acid residues Lys-835 and Arg-894 of maize PEPC, which correspond to Lys-773 and Arg-832 of Escherichia coli PEPC, respectively, were replaced by Gly, since they had been shown to be involved in the binding of allosteric inhibitors, malate or aspartate, by our X-ray crystallographic analysis of E. coli PEPC.	Glycine	161-164	MLO-like protein 4	Zea mays	124-128
10391916-12	1999	LAT-2 exhibits higher affinity (Km = 30-50 microM) to Tyr, Phe, Trp, Thr, Asn, Ile, Cys, Ser, Leu, Val, and Gln and relatively lower affinity (Km = 180-300 microM) to His, Ala, Met, and Gly.	Glycine	186-189	solute carrier family 7 member 8	Rattus norvegicus	0-5
9611271-10	1998	Comparison of amino acid content revealed that BmP109 contained much more cysteine and lysine but less glycine and arginine than the antiapoptotic proteins.	Glycine	103-110	saposin-related	Bombyx mori	47-53
10419831-2	1999	In the present example, connective tissue-activating peptide (CTAPIII) and neutrophil-activating peptide 2 (NAP/2) were generated by digestion of a ubiquitin-CTAPIII conjugate with YUH1 and HIV Pr, respectively, as indicated below: [see text] YUH1 cleaved at the peptide bond formed by the C-terminal Gly(76) of ubiquitin (Ub) and the N-terminal Asn(1) of the 85-residue peptide CTAPIII.	Glycine	301-304	ubiquitin-specific protease YUH1	Saccharomyces cerevisiae S288C	181-185
18408221-4	2008	Firstly, amino acid residues Lys-835 and Arg-894 of maize PEPC, which correspond to Lys-773 and Arg-832 of Escherichia coli PEPC, respectively, were replaced by Gly, since they had been shown to be involved in the binding of allosteric inhibitors, malate or aspartate, by our X-ray crystallographic analysis of E. coli PEPC.	Glycine	161-164	MLO-like protein 4	Zea mays	124-128
18089754-6	2008	The mCAT1/insG receptor (with a Gly residue inserted at mCAT1 position 236) had greatly reduced Mo-MLV receptor function compared with mCAT1.	Glycine	32-35	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	4-9
10369661-1	1999	Glutathione synthetase (GS) catalyses the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner.	Glycine	100-107	glutathione synthetase	Homo sapiens	0-22
9618561-1	1998	In the present study, high levels of peptidylglycine alpha-amidating monooxygenase (PAM), which catalyzes the two-step formation of bioactive alpha-amidated peptides from their glycine-extended precursors, have been found in the uterus.	Glycine	45-52	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	84-87
18089754-6	2008	The mCAT1/insG receptor (with a Gly residue inserted at mCAT1 position 236) had greatly reduced Mo-MLV receptor function compared with mCAT1.	Glycine	32-35	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	56-61
18089754-6	2008	The mCAT1/insG receptor (with a Gly residue inserted at mCAT1 position 236) had greatly reduced Mo-MLV receptor function compared with mCAT1.	Glycine	32-35	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	56-61
9600953-3	1998	We previously demonstrated that a glycine to serine mutation in pinB is linked inseparably to grain hardness.	Glycine	34-41	puroindoline b-like protein 2v1	Triticum aestivum	64-68
9600953-8	1998	The absence of pinA protein and transcript and a glycine-to-serine mutation in pinB are two highly conserved mutations associated with grain hardness, and these friabilin genes are the suggested tightly linked components of the Hardness gene.	Glycine	49-56	puroindoline b-like protein 2v1	Triticum aestivum	79-83
18289107-3	2008	Alanine:glyoxylate aminotransferase (AGT) is a peroxisomal pyridoxal 5"-phosphate (PLP) dependent enzyme which catalyzes the transamination of alanine and glyoxylate to pyruvate and glycine.	Glycine	182-189	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	0-35
10347200-4	1999	Asp-454, Ile-455, and Gly-457 of smooth muscle myosin were substituted by Ala, Met, and Ala, respectively, and the mechano-enzymatic activities were determined to study the role of these residues in myosin motor function.	Glycine	22-25	myosin heavy chain 14	Homo sapiens	47-53
10339411-7	1999	Myristoylation of the N-terminal glycine residue leads to stabilization of both helices, H1 and H2.	Glycine	33-40	H1.5 linker histone, cluster member	Homo sapiens	89-98
10217297-7	1999	Stimulation with glutamate or NMDA and glycine also caused a rise of R in external Cd2+.	Glycine	39-46	CD2 molecule	Homo sapiens	83-86
10395214-3	1999	We examined the polymorphic serine to glycine substitution in the first exon of the gene encoding the dopamine D3 receptor (DRD3) inn 53 schizophrenia patients with TD, 63 matched patients with similar antipsychotic exposure but no TD and 117 normal controls.	Glycine	38-45	dopamine receptor D3	Homo sapiens	124-128
10218494-2	1999	However, another form of GnRH of unknown function (pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly; GnRH-II) is expressed in the mesencephalon of all vertebrate classes except jawless fish.	Glycine	72-75	gonadotropin releasing hormone 1	Mus musculus	25-29
10218494-2	1999	However, another form of GnRH of unknown function (pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly; GnRH-II) is expressed in the mesencephalon of all vertebrate classes except jawless fish.	Glycine	72-75	gonadotropin releasing hormone 1	Mus musculus	93-97
10598551-2	1999	Folylpoly-gamma-glutamate synthetase has three functions in folate homeostasis in mammals: polyglutamation prevents efflux of folate cofactors from the cell, it increases the binding of folate cofactors to some of the enzymes of folate interconversion and biosynthesis, and it appears to allow the accumulation of folates in the mitochondria that are required for glycine synthesis.	Glycine	364-371	folylpolyglutamate synthase	Homo sapiens	0-36
10064624-0	1999	Immunomodulatory effects of glycine on LPS-treated monocytes: reduced TNF-alpha production and accelerated IL-10 expression.	Glycine	28-35	interleukin 10	Rattus norvegicus	107-112
10064624-6	1999	GLY decreased LPS-induced TNF-alpha production (P&lt;0.01) and increased IL-10 expression of purified monocytes.	Glycine	0-3	interleukin 10	Rattus norvegicus	73-78
10064624-7	1999	Similarly, in a whole blood assay, GLY reduced TNF-alpha (P&lt;0.0001) and IL-1beta (P&lt;0.0001) synthesis and increased IL-10 expression (P&lt;0.05) in a dose-dependent manner.	Glycine	35-38	interleukin 10	Rattus norvegicus	122-127
10064624-8	1999	The inhibitory effects of GLY were neutralized by strychnine, and the production of IL-10 and TNF-alpha was augmented by anti-IL-10 antibodies.	Glycine	26-29	interleukin 10	Rattus norvegicus	126-131
10022120-6	1999	Mutation at a loss-of-function site (Gly-298) in Cbl-b-N disrupts its interaction with Syk.	Glycine	37-40	Cbl proto-oncogene B	Homo sapiens	49-54
10065998-4	1999	Glycine activated currents in these cells with EC50s of 101+/-7 or 112+/-23 microM for cells stably expressing alpha1 or alpha2 receptors, respectively.	Glycine	0-7	adrenoceptor alpha 1D	Homo sapiens	111-117
10470377-12	1999	Cells expressing FPGS activity solely in the mitochondria are glycine prototrophs, but also possess cytosolic folylpolyglutamates and are prototrophic for thymidine and purines, products of cytosolic one carbon metabolism.	Glycine	62-69	folylpolyglutamate synthase	Homo sapiens	17-21
10544372-7	1999	Glycine levels were significantly higher in the contralateral DG and ipsilateral CA1 in the sham groups compared to intact anesthetic controls (p &lt; 0.05).	Glycine	0-7	carbonic anhydrase 1	Cavia porcellus	81-84
21380910-5	1999	The focus of this chapter is to describe the preparation of a novel cyclopropane-containing cis-substituted (-Glypsi[CHOH-cp-CONH]-) subunit, which replaces Gly(2)-Gly(3) subunit of the Leu-enkephalin (Tyr-Gly-Gly-Phe-Leu) framework shown in Fig.	Glycine	110-113	prodynorphin	Homo sapiens	186-200
9833913-8	1998	We also analyzed the effect of Arg-Gly-Asp containing peptides on the expression of smooth muscle alpha actin by immunocytochemistry and immunoblotting.	Glycine	35-38	actin alpha 2, smooth muscle	Rattus norvegicus	84-109
9765407-2	1998	We report here the expression of soluble integrin alphav beta5, which retains the ability to recognize the Ad penton base as well as vitronectin, an Arg Gly Asp (RGD)-containing extracellular matrix protein.	Glycine	153-156	adaptor related protein complex 5 subunit beta 1	Homo sapiens	57-62
9722148-11	1998	To conclude, gp120 may act following recognition by its V3 sequence of a high-affinity site possibly coincident with the glycine site of N-methyl-D-aspartate receptors present on hippocampal terminals of noradrenergic neurons.	Glycine	121-128	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	13-18
9765264-3	1998	By using the combinatorial methods of synthetic substrate libraries and substrate-phage display, an optimal substrate for granzyme B that spans over six subsites was determined to be Ile-Glu-Xaa-(Asp downward arrowXaa)-Gly, with cleavage of the Asp downward arrowXaa peptide bond.	Glycine	219-222	granzyme B	Homo sapiens	122-132
9811630-2	1998	Intra- and interspecific work on per has focused mostly on a region of Thr-Gly or Ser-Gly repeats, which show rapid length and sequence evolution.	Glycine	75-78	period	Drosophila melanogaster	33-36
9811630-2	1998	Intra- and interspecific work on per has focused mostly on a region of Thr-Gly or Ser-Gly repeats, which show rapid length and sequence evolution.	Glycine	86-89	period	Drosophila melanogaster	33-36
9753690-2	1998	As an enzyme of the thymidylate synthase metabolic cycle, SHMT catalyses the retro-aldol cleavage of serine to glycine, with the resulting hydroxymethyl group being transferred to tetrahydrofolate to form 5, 10-methylene-tetrahydrofolate.	Glycine	111-118	serine hydroxymethyltransferase 1	Homo sapiens	58-62
9758269-4	1998	RESULT: The mean glycine deficit during TCRE was found to be 474.45 ml, with a mean total inflow of 3802.17 ml.	Glycine	17-24	CD3 epsilon subunit of T-cell receptor complex	Homo sapiens	40-44
9727075-2	1998	We have previously found that mouse hematopoietic stem cells could be transduced on a FN fragment that included the recognition sequence Arg-Gly-Asp (RGD), suggesting that stem cells may express the integrin very late antigen (VLA)-5.	Glycine	141-144	fibronectin 1	Mus musculus	86-88
9727075-2	1998	We have previously found that mouse hematopoietic stem cells could be transduced on a FN fragment that included the recognition sequence Arg-Gly-Asp (RGD), suggesting that stem cells may express the integrin very late antigen (VLA)-5.	Glycine	141-144	integrin alpha 5 (fibronectin receptor alpha)	Mus musculus	208-233
9726286-4	1998	Higher concentrations of ethanol (100 mM and 200 mM) significantly potentiated glycine responses only in stably transfected Ltk- cells expressing alpha1 and alpha2 subunits and in HEK 293 cells transiently expressing alpha2 subunits.	Glycine	79-86	leukocyte receptor tyrosine kinase	Homo sapiens	124-127
9726286-4	1998	Higher concentrations of ethanol (100 mM and 200 mM) significantly potentiated glycine responses only in stably transfected Ltk- cells expressing alpha1 and alpha2 subunits and in HEK 293 cells transiently expressing alpha2 subunits.	Glycine	79-86	adrenoceptor alpha 1D	Homo sapiens	146-152
9787461-7	1998	Glucose 6-phosphate and glycine had little effect on the root-form PEPC at pH 7.3; they caused two-fold activation of the C4-form PEPC.	Glycine	24-31	MLO-like protein 4	Zea mays	130-134
9703961-7	1998	This is the first demonstration that PC1 acting alone is able to cleave pro CCK liberating the amino terminal pro peptide and a glycine and arginine extended CCK 8 which is the immediate precursor of CCK 8 amide.	Glycine	128-135	proprotein convertase subtilisin/kexin type 1	Homo sapiens	37-40
9556603-8	1998	[3H]CGP 61594 is a promising tool to identify the NR2 subunit domains that contribute to differential glycine antagonist sites of NMDA receptor subtypes.	Glycine	102-109	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	130-143
9572491-7	1998	Strikingly, these cells contain a missense mutation of the p53 gene at codon 242 (p53(242)), which substitutes alanine for glycine.	Glycine	123-130	transformation related protein 53, pseudogene	Mus musculus	59-62
9572491-7	1998	Strikingly, these cells contain a missense mutation of the p53 gene at codon 242 (p53(242)), which substitutes alanine for glycine.	Glycine	123-130	transformation related protein 53, pseudogene	Mus musculus	82-85
9548757-11	1998	Cleavage between the Gly and Ser residues of the reactive site loop and detection of a stable SCCA1-cathepsin S complex by sodium dodecyl sulfate-polyacrylamide gel electrophoresis suggested that the serpin interacted with the cysteine proteinase in a manner similar to that observed for typical serpin-serine proteinase interactions.	Glycine	21-24	serpin family B member 3	Homo sapiens	94-99
9579822-11	1998	The missense mutation reported here suggests that the BRCA2 domain including and surrounding glycine 2901 may be more important in preventing neoplastic transformation in ovarian epithelium than in breast epithelium.	Glycine	93-100	breast cancer 2, early onset	Mus musculus	54-59
9485396-0	1998	Structure, function, and temperature sensitivity of directed, random mutants at proline 76 and glycine 77 in omega-loop D of yeast iso-1-cytochrome c. Residues 75-78 form a tight turn within Omega-loop D in Saccharomyces cerevisiae iso-1-cytochrome c. Directed, random mutagenesis of invariant residues proline 76 and glycine 77 in this turn were analyzed for the in vivo functionality and level of protein within the cell.	Glycine	95-102	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	131-136
9485396-0	1998	Structure, function, and temperature sensitivity of directed, random mutants at proline 76 and glycine 77 in omega-loop D of yeast iso-1-cytochrome c. Residues 75-78 form a tight turn within Omega-loop D in Saccharomyces cerevisiae iso-1-cytochrome c. Directed, random mutagenesis of invariant residues proline 76 and glycine 77 in this turn were analyzed for the in vivo functionality and level of protein within the cell.	Glycine	318-325	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	131-136
9509996-5	1998	However, whereas GLYT2a is able to actively accumulate glycine into transfected COS cells, GLYT2b seems only to exchange (or release) glycine.	Glycine	55-62	solute carrier family 6 member 5	Rattus norvegicus	17-22
9509996-5	1998	However, whereas GLYT2a is able to actively accumulate glycine into transfected COS cells, GLYT2b seems only to exchange (or release) glycine.	Glycine	134-141	solute carrier family 6 member 5	Rattus norvegicus	91-96
9572847-9	1998	The introduction of glycine into the modified betaF-betaG loop, however, generally eliminated conformational changes required by DeltaG121 DHFR to attain the Michaelis complex.	Glycine	20-27	Dihydrofolate reductase	Escherichia coli	139-143
9589236-1	1998	OBJECTIVE: To assess the relevance of a Gly--&gt;Arg substitution in codon 972 of the insulin receptor substrate-1 gene in impaired glucose tolerance (IGT) and NIDDM.	Glycine	40-43	insulin receptor substrate 1	Homo sapiens	86-114
9536084-3	1998	Mutations of the invariant glycine residues in the triple-helical domain-coding region of COL6A1 and COL6A2 have been reported previously in the chromosome 21-linked families.	Glycine	27-34	collagen type VI alpha 1 chain	Homo sapiens	90-96
9536084-4	1998	We report here the identification of a G-->A mutation in the N-terminal globular domain-coding region of COL6A3 in a large American pedigree (19 affected, 12 unaffected), leading to the substitution of glycine by glutamic acid in the N2 motif, which is homologous to the type A domains of the von Willebrand factor.	Glycine	202-209	collagen type VI alpha 3 chain	Homo sapiens	105-111
9556556-11	1998	By peptide analysis using mass spectrometry and Edman degradation, both the cysteine and the selenocysteine in the conserved carboxyl-terminal sequence Gly-Cys-Sec-Gly (where Sec indicates selenocysteine) were determined to be dinitrophenyl-alkylated upon incubation of native TrxR with NADPH and DNCB.	Glycine	152-155	peroxiredoxin 5	Homo sapiens	277-281
9556556-11	1998	By peptide analysis using mass spectrometry and Edman degradation, both the cysteine and the selenocysteine in the conserved carboxyl-terminal sequence Gly-Cys-Sec-Gly (where Sec indicates selenocysteine) were determined to be dinitrophenyl-alkylated upon incubation of native TrxR with NADPH and DNCB.	Glycine	164-167	peroxiredoxin 5	Homo sapiens	277-281
9556603-0	1998	Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes.	Glycine	19-26	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	47-76
9556603-2	1998	The binding site for the co-agonist glycine on N-methyl-D-aspartate (NMDA) receptors has been mapped to the NR1 subunit whereas binding of the principal agonist glutamate is mediated by the NR2 subunits.	Glycine	36-43	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	108-111
9556603-3	1998	Using the novel glycine site antagonist and photoaffinity label CGP 61594, distinct contributions of the NR2 subunit variants to the glycine antagonist binding domains of NMDA receptor subtypes are demonstrated.	Glycine	16-23	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	171-184
9556603-3	1998	Using the novel glycine site antagonist and photoaffinity label CGP 61594, distinct contributions of the NR2 subunit variants to the glycine antagonist binding domains of NMDA receptor subtypes are demonstrated.	Glycine	133-140	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	171-184
9556603-7	1998	Thus, [3H]CGP 61594 is the first antagonist radioligand that reliably distinguishes the glycine site of NMDA receptor subtypes.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	104-117
9526012-1	1998	The amino acids L-glutamate and glycine are essential agonists of the excitatory NMDA receptor, a subtype of the ionotropic glutamate receptor family.	Glycine	32-39	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	81-94
9526012-3	1998	Here, the numbers of glycine-binding NR1 and glutamate-binding NR2 subunits in the NMDA receptor hetero-oligomer were determined by coexpressing the wild-type (wt) NR1 with the low-affinity mutant NR1(Q387K), and the wt NR2B with the low-affinity mutant NR2BE387A, subunits in Xenopus oocytes.	Glycine	21-28	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	37-40
9526012-3	1998	Here, the numbers of glycine-binding NR1 and glutamate-binding NR2 subunits in the NMDA receptor hetero-oligomer were determined by coexpressing the wild-type (wt) NR1 with the low-affinity mutant NR1(Q387K), and the wt NR2B with the low-affinity mutant NR2BE387A, subunits in Xenopus oocytes.	Glycine	21-28	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	83-96
9526012-3	1998	Here, the numbers of glycine-binding NR1 and glutamate-binding NR2 subunits in the NMDA receptor hetero-oligomer were determined by coexpressing the wild-type (wt) NR1 with the low-affinity mutant NR1(Q387K), and the wt NR2B with the low-affinity mutant NR2BE387A, subunits in Xenopus oocytes.	Glycine	21-28	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	164-167
9526012-3	1998	Here, the numbers of glycine-binding NR1 and glutamate-binding NR2 subunits in the NMDA receptor hetero-oligomer were determined by coexpressing the wild-type (wt) NR1 with the low-affinity mutant NR1(Q387K), and the wt NR2B with the low-affinity mutant NR2BE387A, subunits in Xenopus oocytes.	Glycine	21-28	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	164-167
9525872-0	1998	A Gly --&gt; Ser change causes defective folding in vitro of calcium-binding epidermal growth factor-like domains from factor IX and fibrillin-1.	Glycine	2-5	fibrillin 1	Homo sapiens	133-144
9525872-2	1998	A mutation that changes a highly conserved Gly residue to Ser in this domain has been identified both in the factor IX (FIX) and fibrillin-1 genes, where it is associated with relatively mild variants of hemophilia B and Marfan syndrome, respectively.	Glycine	43-46	fibrillin 1	Homo sapiens	129-140
9525872-5	1998	In contrast, the Gly --&gt; Ser change causes defective folding of FIX and fibrillin-1 cbEGF domains.	Glycine	17-20	fibrillin 1	Homo sapiens	75-86
9521723-5	1998	Rather, a combination of a dimeric structure and the introduction of two glycine residues at positions 38 and 111 on the periphery of the active site confers the full catalytic activity of bovine seminal RNase against duplex RNA.	Glycine	73-80	seminal ribonuclease	Bos taurus	196-209
9551089-11	1998	To get further insight into the mechanism of the paradoxical activation of receptor signalling by the R86P mutation, the codons for proline, alanine, and glycine were substituted in the R86 position of the insulin receptor cDNA by PCR-mediated mutagenesis and stably transfected into Chinese hamster ovary (CHO) cells.	Glycine	154-161	insulin receptor	Cricetulus griseus	206-222
9521672-1	1998	5-Aminolevulinate synthase (ALAS) catalyzes the first step in the heme biosynthetic pathway in nonplant eukaryotes and some prokaryotes, which is the condensation of glycine with succinyl-coenzyme A to yield coenzyme A, carbon dioxide, and 5-aminolevulinate.	Glycine	166-173	aminolevulinic acid synthase 1	Mus musculus	0-26
9521672-1	1998	5-Aminolevulinate synthase (ALAS) catalyzes the first step in the heme biosynthetic pathway in nonplant eukaryotes and some prokaryotes, which is the condensation of glycine with succinyl-coenzyme A to yield coenzyme A, carbon dioxide, and 5-aminolevulinate.	Glycine	166-173	aminolevulinic acid synthase 1	Mus musculus	28-32
9452416-5	1998	Covalent modification of PML requires the conserved Gly residue near the C termini of sentrin proteins.	Glycine	52-55	PML nuclear body scaffold	Homo sapiens	25-28
10221825-2	1998	Progastrin, glycine-extended gastrin and amidated gastrin were detected in cell extracts or conditioned media by radio-immunoassay.	Glycine	12-19	gastrin	Homo sapiens	29-36
10221825-3	1998	Low-affinity binding sites for glycine-extended gastrin and amidated gastrin were present, but high-affinity binding sites were not detected with the appropriate iodinated ligands.	Glycine	31-38	gastrin	Homo sapiens	48-55
10221825-3	1998	Low-affinity binding sites for glycine-extended gastrin and amidated gastrin were present, but high-affinity binding sites were not detected with the appropriate iodinated ligands.	Glycine	31-38	gastrin	Homo sapiens	69-76
9442102-3	1998	SUMO-1 is linked to RanGAP1 via glycine 97, indicating that the last 4 amino acids of this 101- amino acid protein are proteolytically removed before its attachment to RanGAP1.	Glycine	32-39	Ran GTPase activating protein 1	Homo sapiens	20-27
9422722-6	1998	Mutations of Val-123, Leu-126, Gly-127, and Ile-128 affected the ability of PCNA to stimulate DNA synthesis by pol delta in several different assays.	Glycine	31-34	proliferating cell nuclear antigen	Homo sapiens	76-80
9891762-4	1998	On the contrary, concentrations of glutamate and glycine increased more after water bath heating at 90 degrees C (325 +/- 4 and 101 +/- 1 mumol/1, respectively) than after microwave heating (312 +/- 4 and 95 +/- 1 mumol/l, respectively, p &lt; 0.05) suggesting milk proteolysis.	Glycine	49-56	complement C4A (Rodgers blood group)	Homo sapiens	111-145
9485196-8	1998	A variant of GCP-2 in which the basic residue, Arg20, was replaced by a glycine was synthesized.	Glycine	72-79	C-X-C motif chemokine ligand 6	Homo sapiens	13-18
9388228-4	1997	Trx2 contains two distinct domains: an N-terminal domain of 32 amino acids including two CXXC motifs and a C-terminal domain, with the conserved active site, Trp-Cys-Gly-Pro-Cys, showing high homology to the prokaryotic thioredoxins.	Glycine	166-169	thioredoxin 2	Homo sapiens	0-4
9422818-6	1997	Oocytes expressing alpha 1 and alpha 1 beta glycine receptors subsequent to cDNA injection displayed EC50 values of 76 +/- 2 microM and 66 +/- 2 microM, respectively, in response to bath applied glycine.	Glycine	44-51	adrenoceptor alpha 1D	Homo sapiens	31-38
9422818-16	1997	The barbiturate also produced a substantial enhancement of the glycine-evoked currents, Imax and EC50 values being 71 +/- 2% and 845 +/- 66 microM and 51 +/- 10% and 757 +/- 30 microM for homomeric alpha 1 and heteromeric alpha 1 beta glycine receptors respectively.	Glycine	63-70	adrenoceptor alpha 1D	Homo sapiens	198-205
9422818-16	1997	The barbiturate also produced a substantial enhancement of the glycine-evoked currents, Imax and EC50 values being 71 +/- 2% and 845 +/- 66 microM and 51 +/- 10% and 757 +/- 30 microM for homomeric alpha 1 and heteromeric alpha 1 beta glycine receptors respectively.	Glycine	63-70	adrenoceptor alpha 1D	Homo sapiens	222-229
9422818-19	1997	The potentiation by propofol or pentobarbitone of currents mediated by alpha 1 homo-oligomeric glycine receptors was in both cases associated with a parallel sinistral shift of the glycine concentration-effect curve.	Glycine	95-102	adrenoceptor alpha 1D	Homo sapiens	71-78
9422818-23	1997	By contrast, glycine-induced currents mediated by alpha 1 and alpha 1 beta glycine receptor isoforms were enhanced only to 29 +/- 4% and 28 +/- 3% of Imax.	Glycine	13-20	adrenoceptor alpha 1D	Homo sapiens	50-57
9422818-23	1997	By contrast, glycine-induced currents mediated by alpha 1 and alpha 1 beta glycine receptor isoforms were enhanced only to 29 +/- 4% and 28 +/- 3% of Imax.	Glycine	13-20	adrenoceptor alpha 1D	Homo sapiens	62-69
9422818-31	1997	Trichloroethanol, the active metabolite of the general anaesthetic chloral hydrate, enhanced glycine-evoked currents to 77 +/- 10% and 94 +/- 4% of Imax on alpha 1 and alpha 1 beta glycine receptors, with EC50 values of 3.5 +/- 0.1 mM and 5.9 +/- 0.3 mM respectively.	Glycine	93-100	adrenoceptor alpha 1D	Homo sapiens	156-163
9422818-31	1997	Trichloroethanol, the active metabolite of the general anaesthetic chloral hydrate, enhanced glycine-evoked currents to 77 +/- 10% and 94 +/- 4% of Imax on alpha 1 and alpha 1 beta glycine receptors, with EC50 values of 3.5 +/- 0.1 mM and 5.9 +/- 0.3 mM respectively.	Glycine	93-100	adrenoceptor alpha 1D	Homo sapiens	168-175
9389509-1	1997	Peptidylglycine alpha-amidating monooxygenase (PAM; EC 1.14.17.3) is a bifunctional protein containing two enzymes that act sequentially to catalyze the conversion of glycine-extended peptides into COOH-terminal amidated peptides.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	47-50
9393711-1	1997	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to glycine with the transfer of the one-carbon group to tetrahydrofolate to form 5,10-methylenetetrahydrofolate.	Glycine	86-93	SULB_RS08175	Saccharolobus solfataricus	0-31
9393711-1	1997	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to glycine with the transfer of the one-carbon group to tetrahydrofolate to form 5,10-methylenetetrahydrofolate.	Glycine	86-93	SULB_RS08175	Saccharolobus solfataricus	33-37
9398173-1	1997	The catalytic general base, Pro-1, of the enzyme 4-oxalocrotonate tautomerase has been mutated to Gly, Ala, Val, and Leu, residues with aliphatic side chains.	Glycine	98-101	lamin A/C	Homo sapiens	28-33
9385632-2	1997	We demonstrate that the capsid sequence 87His-Ala-Gly-Pro-Ile-Ala92 (87HAGPIA92) encompasses the primary cyclophilin A binding site and present an X-ray crystal structure of the CypA/HAGPIA complex.	Glycine	50-53	peptidylprolyl isomerase A	Homo sapiens	105-118
9385632-2	1997	We demonstrate that the capsid sequence 87His-Ala-Gly-Pro-Ile-Ala92 (87HAGPIA92) encompasses the primary cyclophilin A binding site and present an X-ray crystal structure of the CypA/HAGPIA complex.	Glycine	50-53	peptidylprolyl isomerase A	Homo sapiens	178-182
9341155-1	1997	Rat liver cytosolic glycine N-methyltransferase (GNMT) catalyzes the S-adenosylmethionine-dependent methylation of glycine to sarcosine.	Glycine	20-27	glycine N-methyltransferase	Rattus norvegicus	49-53
9334257-17	1997	The deduced amino acid sequence revealed that the putative protein contains all the canonical features of a novel glycine-rich hnRNP.	Glycine	114-121	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	127-132
9305971-0	1997	Properties of early photolysis intermediates of rhodopsin are affected by glycine 121 and phenylalanine 261.	Glycine	74-81	rhodopsin	Bos taurus	48-57
9305971-1	1997	Glycine 121 in transmembrane (TM) helix 3 and phenylalanine 261 in TM helix 6 of bovine rhodopsin have been shown to be critical residues for creating an appropriate chromophore binding pocket for 11-cis-retinal [Han, M., Lin, S. W., Smith, S. O., and Sakmar, T. P. (1996) J. Biol.	Glycine	0-7	rhodopsin	Bos taurus	88-97
9311595-8	1997	These data demonstrate that peptide vaccination with a single mutant p21-ras-derived peptide induces CD4+ and CD8+ CTL specific for nested epitopes, including the Gly --&gt; Val substitution at codon 12, and that both these T-cell sub-sets specifically recognize tumour cells harbouring the corresponding K-ras mutation.	Glycine	163-166	H3 histone pseudogene 16	Homo sapiens	69-72
9391907-1	1997	On the basis of the X-ray structure and results from structure-activity relationship studies, the following GM-CSF analogue was designed and synthesized by solid-phase methodology: hGM-CSF[13-31]-Gly-Pro-Gly-[103-116]-NH2.	Glycine	196-199	colony stimulating factor 2	Homo sapiens	108-114
9391907-1	1997	On the basis of the X-ray structure and results from structure-activity relationship studies, the following GM-CSF analogue was designed and synthesized by solid-phase methodology: hGM-CSF[13-31]-Gly-Pro-Gly-[103-116]-NH2.	Glycine	196-199	colony stimulating factor 2	Homo sapiens	181-188
9391907-1	1997	On the basis of the X-ray structure and results from structure-activity relationship studies, the following GM-CSF analogue was designed and synthesized by solid-phase methodology: hGM-CSF[13-31]-Gly-Pro-Gly-[103-116]-NH2.	Glycine	204-207	colony stimulating factor 2	Homo sapiens	108-114
9391907-1	1997	On the basis of the X-ray structure and results from structure-activity relationship studies, the following GM-CSF analogue was designed and synthesized by solid-phase methodology: hGM-CSF[13-31]-Gly-Pro-Gly-[103-116]-NH2.	Glycine	204-207	colony stimulating factor 2	Homo sapiens	181-188
9268369-2	1997	Sex-lethal (Sxl) is an RNA-binding protein, containing two conserved RNA binding domains (RBDs) and a glycine-rich region, which functions as a regulator of alternative splicing in Drosophila sex determination.	Glycine	102-109	Sex lethal	Drosophila melanogaster	0-10
9268369-2	1997	Sex-lethal (Sxl) is an RNA-binding protein, containing two conserved RNA binding domains (RBDs) and a glycine-rich region, which functions as a regulator of alternative splicing in Drosophila sex determination.	Glycine	102-109	Sex lethal	Drosophila melanogaster	12-15
9268369-3	1997	Previous work demonstrated that Sxl monomers interact cooperatively upon binding to target RNAs and that the cooperativity depends on the glycine-rich N terminus.	Glycine	138-145	Sex lethal	Drosophila melanogaster	32-35
9268369-4	1997	Here we use band shift experiments to show that RNA binding patterns are altered when Sxl is combined with other proteins having similar glycine-rich domains, including mammalian heterogeneous nuclear (hn) RNP L and Drosophila Hrb87F (an hnRNP A/B homolog).	Glycine	137-144	Sex lethal	Drosophila melanogaster	86-89
9268369-5	1997	Direct involvement of the Sxl glycine-rich region in protein interactions was verified by Far-Western analysis.	Glycine	30-37	Sex lethal	Drosophila melanogaster	26-29
9305787-2	1997	The second analog, CB-2, is identical to CB-1 except for the insertion of a Gly-Pro residue pair between Pro-24 and Ala-25.	Glycine	76-79	cannabinoid receptor 2	Homo sapiens	19-23
9261168-9	1997	In the case of K8/K18, however, the interaction as assessed by yeast two-hybrid assays increased 9-fold when a serine located in a protein kinase A consensus phosphorylation site 23 residues from the end of DP was altered to a glycine.	Glycine	227-234	desmoplakin	Homo sapiens	207-209
9245714-0	1997	Tyrosine phosphorylation of insulin receptor substrate-1 and activation of the PI-3-kinase pathway by glycine-extended gastrin precursors.	Glycine	102-109	gastrin	Homo sapiens	119-126
9245714-1	1997	Glycine-extended gastrin precursors (G-Gly) were considered as processing intermediates devoid of biological activity.	Glycine	0-7	gastrin	Homo sapiens	17-24
9260929-0	1997	Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion.	Glycine	124-127	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	0-11
9260929-0	1997	Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion.	Glycine	124-127	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	22-26
9260929-2	1997	Previously, we have shown that the mature protein, formerly known as BA46, has three domains: an epidermal growth factor (EGF)-like domain containing an Arg-Gly-Asp (RGD) cell adhesion sequence and C1 and C2 domains similar to those found in coagulation factors V and VIII.	Glycine	157-160	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	69-73
9202292-3	1997	Another case of RNA editing alters an arginine (R) to a glycine (G) codon at a position termed the "R/G" site of AMPA subunits GluR-B, C, and D. Double-stranded RNA-specific adenosine deaminases (DRADA) have been implicated as agents involved in the editing.	Glycine	56-63	adenosine deaminase RNA specific	Homo sapiens	145-194
9200692-3	1997	Kinetic analysis indicated that antithrombin (AT with P2 Gly) inhibited thrombin L99Y, 14.1- and 5.5-fold slower than thrombin in the absence and presence of heparin, respectively.	Glycine	57-60	serpin family C member 1	Homo sapiens	32-44
9169429-7	1997	Inhibition of PAM resulted in a concomitant increase in the glycine-extended substance p (substance P-Gly) precursor peptide.	Glycine	60-67	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	14-17
9169429-7	1997	Inhibition of PAM resulted in a concomitant increase in the glycine-extended substance p (substance P-Gly) precursor peptide.	Glycine	102-105	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	14-17
9208944-1	1997	Glycine-extended forms of gastrin (gastrin-Gly) are thought to be involved in the autocrine growth control of colorectal carcinomas.	Glycine	0-7	gastrin	Homo sapiens	26-33
9208944-1	1997	Glycine-extended forms of gastrin (gastrin-Gly) are thought to be involved in the autocrine growth control of colorectal carcinomas.	Glycine	0-7	gastrin	Homo sapiens	35-42
9175779-3	1997	Using the Dictyostelium myosin II heavy chain gene, SH2 was mutated to Gly, Ala, Ser, or Thr.	Glycine	71-74	myosin heavy chain 14	Homo sapiens	24-30
9177774-3	1997	Comparison of the human DMP1-coding sequence with that of the rat, mouse, and cow indicated that the predicted protein contains a conserved hydrophobic signal peptide sequence and an Arg-Gly-Asp cell attachment sequence.	Glycine	187-190	dentin matrix acidic phosphoprotein 1	Homo sapiens	24-28
9111320-4	1997	The carboxyl-terminal tripeptide, Gly-Thr-Leu, of Pex17p is not necessary for its targeting to peroxisomes.	Glycine	34-37	Pex17p	Saccharomyces cerevisiae S288C	50-56
9109651-9	1997	The glycine-rich loop between beta1 and beta2 helps to anchor the phosphates while the ribose ring is buried beneath beta-strand 2.	Glycine	4-11	hemoglobin, beta adult major chain	Mus musculus	30-35
9092508-7	1997	The concentration of fragments derived from the C-terminal telopeptide region of type I collagen containing the sequence Asp-Gly (alphaCTX) and/or betaAsp-Gly (betaCTX) was measured by enzyme-linked immunosorbent assays in urine and in collagenase digests of trabecular and cortical bone of young and old origin.	Glycine	125-128	adrenoceptor alpha 1D	Homo sapiens	78-96
9148753-6	1997	MMP-7 cleaves DCN into three major fragments which have the N-termini Asp1-Glu-Ala-Ser-Gly, Glu2-Ala-Ser-Gly-Ile and Leu244-His-Leu-Asp-Asn.	Glycine	87-90	matrix metallopeptidase 7	Homo sapiens	0-5
9148753-6	1997	MMP-7 cleaves DCN into three major fragments which have the N-termini Asp1-Glu-Ala-Ser-Gly, Glu2-Ala-Ser-Gly-Ile and Leu244-His-Leu-Asp-Asn.	Glycine	87-90	decorin	Homo sapiens	14-17
9073168-6	1997	In vitro expression studies have shown that the NR1-NR2C subunit combination exhibits weaker magnesium block and higher affinity for glycine than NR1-NR2B.	Glycine	133-140	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	48-51
9030536-6	1997	The 11-kDa species contains no post-translational modifications and consists of an extended IGF-II backbone terminating at Gly-87.	Glycine	123-126	insulin like growth factor 2	Homo sapiens	92-98
9037010-4	1997	The C-terminal region of kinesin-73 protein contains a cytoskeleton associated protein Gly-rich domain, which is a putative microtubule binding site that is present in some cytoskeleton or dynein-associated proteins.	Glycine	87-90	Kinesin heavy chain 73	Drosophila melanogaster	25-35
9020120-0	1997	Molecular determinants of arg-gly-asp ligand specificity for beta3 integrins.	Glycine	30-33	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	Mus musculus	61-66
9066982-0	1997	Association of an exon 3 mutation (Trp66--&gt;Gly) of the LDL receptor with variable expression of familial hypercholesterolemia in a French Canadian family.	Glycine	46-49	low density lipoprotein receptor	Homo sapiens	58-70
9066982-0	1997	Association of an exon 3 mutation (Trp66--&gt;Gly) of the LDL receptor with variable expression of familial hypercholesterolemia in a French Canadian family.	Glycine	46-49	low density lipoprotein receptor	Homo sapiens	99-128
9066982-3	1997	In the current investigation, we documented the presence of two identical mutant LDL receptor alleles (Trp66--&gt;Gly) in two familial hypercholesterolemia (FH) probands, II-1 and II-2, associated with markedly elevated plasma LDL cholesterol (17.22 +/- 0.78 and 11.95 +/- 0.24 mmol/liter, respectively).	Glycine	114-117	low density lipoprotein receptor	Homo sapiens	81-93
9066982-3	1997	In the current investigation, we documented the presence of two identical mutant LDL receptor alleles (Trp66--&gt;Gly) in two familial hypercholesterolemia (FH) probands, II-1 and II-2, associated with markedly elevated plasma LDL cholesterol (17.22 +/- 0.78 and 11.95 +/- 0.24 mmol/liter, respectively).	Glycine	114-117	low density lipoprotein receptor	Homo sapiens	126-155
9066982-10	1997	Thus, the disturbance of lipoprotein concentration, composition, size, and metabolism may in part be related to the exon 3 mutation (Trp66--&gt;Gly) of the LDL receptor gene.	Glycine	144-147	low density lipoprotein receptor	Homo sapiens	156-168
8999813-7	1997	By deletion analysis, we mapped the apobec-1-binding region to the glycine-rich domain.	Glycine	67-74	apolipoprotein B mRNA editing enzyme catalytic subunit 1	Homo sapiens	36-44
9143692-4	1997	TRX is a small multifunctional protein that has a redox-active disulfide/dithiol within the conserved active site sequence: Cys-Gly-Pro-Cys.	Glycine	128-131	thioredoxin	Homo sapiens	0-3
9012781-8	1997	The expression vectors of an hypophosphorylatable mutant (pKSm, human HSP27 gene in which codons for Ser-15, -78, and -82 were converted to code for Gly by site-directed mutagenesis) as well as C-terminal deletion mutants in which 12-36 amino acid residues from the C-terminus were deleted had no significant effect on the colony-forming efficiency of NIH 3T3 cells.	Glycine	149-152	heat shock protein family B (small) member 1	Homo sapiens	70-75
9606729-1	1997	NMR spectroscopy has been used to obtain structural information on the bioactive conformation of the nonapeptide hormone bradykinin (Arg-Pro-Pro-Gly-Ser-Pro-Phe-Arg, BK) bound to the Fab-fragment of an antibody that mimics the hormone binding site of the natural bradykinin B2-receptor.	Glycine	145-148	FA complementation group B	Homo sapiens	183-186
8986758-10	1996	Together, the structural and kinetic data confirm that F43V is a critical residue in gp120 recognition site, which may also include main chain interactions at residue Gly-47.	Glycine	167-170	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	85-90
9597750-1	1998	Glycine N-methyltransferase (EC 2.1.1.20) catalyzes the transfer of the methyl group of S-adenosylmethionine (AdoMet) to glycine to form S-adenosylhomocysteine and sarcosine.	Glycine	121-128	glycine N-methyltransferase	Rattus norvegicus	0-27
9504406-0	1998	Nonadditive effects of double mutations at the flexible loops, glycine-67 and glycine-121, of Escherichia coli dihydrofolate reductase on its stability and function.	Glycine	63-70	Dihydrofolate reductase	Escherichia coli	111-134
9504406-0	1998	Nonadditive effects of double mutations at the flexible loops, glycine-67 and glycine-121, of Escherichia coli dihydrofolate reductase on its stability and function.	Glycine	78-85	Dihydrofolate reductase	Escherichia coli	111-134
9426281-6	1997	ASE-1 was found to contain two domains that are present in a number of nucleolar specific proteins originating from a variety of organisms: a glycine-, arginine- and phenylalanine-rich putative nucleotide interaction domain and an alternating basic/acidic region.	Glycine	142-149	RNA polymerase I subunit G	Homo sapiens	0-5
9476130-6	1997	This mutation is very similar to a mutation previously described in another case of functional C1q deficiency where Gly at position 6 of the C chain was substituted by a large positively charged residue (Arg).	Glycine	116-119	complement C1q A chain	Homo sapiens	95-98
8913624-2	1996	Linear and cyclic forms of the fibronectin (Fn) cell-binding domain peptide Arg-Gly-Asp (RGD) were covalently immobilized to glass, and Fn was adsorbed onto glass slides.	Glycine	80-83	fibronectin 1	Bos taurus	31-42
8913624-2	1996	Linear and cyclic forms of the fibronectin (Fn) cell-binding domain peptide Arg-Gly-Asp (RGD) were covalently immobilized to glass, and Fn was adsorbed onto glass slides.	Glycine	80-83	fibronectin 1	Bos taurus	44-46
18289107-3	2008	Alanine:glyoxylate aminotransferase (AGT) is a peroxisomal pyridoxal 5"-phosphate (PLP) dependent enzyme which catalyzes the transamination of alanine and glyoxylate to pyruvate and glycine.	Glycine	182-189	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	37-40
18160688-5	2007	RESULTS: We identified three closely located glycine mutations in exons 24 and 25 of the gene COL4A1, which encodes procollagen type IV alpha1.	Glycine	45-52	collagen type IV alpha 1 chain	Homo sapiens	94-100
9367504-1	1997	Serine hydroxymethyltransferase (SHMT) from all sources tested catalyzes the slow exchange of the pro-2S proton of glycine with solvent protons.	Glycine	115-122	serine hydroxymethyltransferase 1	Homo sapiens	0-31
9367504-1	1997	Serine hydroxymethyltransferase (SHMT) from all sources tested catalyzes the slow exchange of the pro-2S proton of glycine with solvent protons.	Glycine	115-122	serine hydroxymethyltransferase 1	Homo sapiens	33-37
17971454-4	2007	The yeast enzyme also contains a conserved glycine residue (Gly80) that is essential for the fat-regulating function of lipin 1 in a mouse model.	Glycine	43-50	lipin 1	Homo sapiens	120-127
9295332-6	1997	Mutation of four glycine residues within two proposed ATP binding motifs diminishes both geldanamycin binding and the ATP-dependent conversion of hsp90 to a conformation capable of binding the co-chaperone p23.	Glycine	17-24	heat shock protein 90 alpha family class A member 1	Homo sapiens	146-151
9295332-6	1997	Mutation of four glycine residues within two proposed ATP binding motifs diminishes both geldanamycin binding and the ATP-dependent conversion of hsp90 to a conformation capable of binding the co-chaperone p23.	Glycine	17-24	prostaglandin E synthase 3	Homo sapiens	206-209
17884813-7	2007	Expression of the Aphanothece PGDH gene in Escherichia coli caused an increase in levels of betaine as well as glycine and serine.	Glycine	111-118	D-3-phosphoglycerate dehydrogenase	Arabidopsis thaliana	30-34
17884813-8	2007	Expression of the Aphanothece PGDH gene in Arabidopsis plants, in which the betaine synthetic pathway was introduced via glycine methylation, further increased betaine levels and improved the stress tolerance.	Glycine	121-128	D-3-phosphoglycerate dehydrogenase	Arabidopsis thaliana	30-34
17884813-9	2007	These results demonstrate that PGDH enhances the levels of betaine by providing the precursor serine for both choline oxidation and glycine methylation pathways.	Glycine	132-139	D-3-phosphoglycerate dehydrogenase	Arabidopsis thaliana	31-35
17970719-0	2007	The contribution of the NMDA receptor glycine site to rhythm generation during fictive swimming in Xenopus laevis tadpoles.	Glycine	38-45	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	24-37
17962467-16	2007	Although GLYT1 and -2 are likely to mediate glycine uptake in cortical fiber cells, GLYT2 alone appears responsible for the accumulation of glycine in the center of the lens.	Glycine	140-147	solute carrier family 6 member 5	Rattus norvegicus	84-89
9335260-0	1997	Gp120 can revert antagonism at the glycine site of NMDA receptors mediating GABA release from cultured hippocampal neurons.	Glycine	35-42	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	0-5
17715129-1	2007	The neuronal K-Cl cotransporter KCC2 maintains the low intracellular chloride concentration required for the hyperpolarizing actions of inhibitory neurotransmitters gamma-aminobutyric acid and glycine in the central nervous system.	Glycine	193-200	solute carrier family 12, member 5	Mus musculus	32-36
17611150-2	2007	In this study, we finally identify the molecular nature of the arg7-8 mutation as a (6073)G to A transition in exon 9 of ARG7 leading to a (288)Gly to Ser exchange near the active site of the protein.	Glycine	144-147	uncharacterized protein	Chlamydomonas reinhardtii	63-69
17611150-2	2007	In this study, we finally identify the molecular nature of the arg7-8 mutation as a (6073)G to A transition in exon 9 of ARG7 leading to a (288)Gly to Ser exchange near the active site of the protein.	Glycine	144-147	uncharacterized protein	Chlamydomonas reinhardtii	121-125
17660294-2	2007	Herein we show that glycine substitution of the VAVIM motif in Ca(V)2.3 produced whole cell currents with inactivation kinetics that were either slower (A1719G approximately V1720G), similar (V1718G), or faster (I1721G approximately M1722G) than the wild-type channel.	Glycine	20-27	calcium voltage-gated channel subunit alpha1 E	Homo sapiens	63-71
17878296-3	2007	This site is not formed by the side-chain carboxylate groups from the conserved acidic residue, Asp-66 in NaK, conventionally thought to directly chelate Ca(2+) in CNG channels, but rather by the backbone carbonyl groups of residue Gly-67.	Glycine	232-235	TANK binding kinase 1	Homo sapiens	106-109
17617428-5	2007	We have previously reported that NR3A contains a glycine binding site, with similar affinity as the glycine binding site of NR1 subunits.	Glycine	49-56	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	33-37
17617428-5	2007	We have previously reported that NR3A contains a glycine binding site, with similar affinity as the glycine binding site of NR1 subunits.	Glycine	100-107	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	33-37
17785674-3	2007	More recently, we found heterozygous COL6A1 glycine substitutions in patients with UCMD with SSCD.	Glycine	44-51	collagen type VI alpha 1 chain	Homo sapiens	37-43
17785674-4	2007	OBJECTIVE: To elucidate how COL6A1 glycine mutation leads to SSCD.	Glycine	35-42	collagen type VI alpha 1 chain	Homo sapiens	28-34
17785674-10	2007	CONCLUSION: Heterozygous glycine substitution in COL6A1 may cause decreased binding of collagen VI microfibrils to the extracellular matrix resulting in sarcolemma-specific collagen VI deficiency.	Glycine	25-32	collagen type VI alpha 1 chain	Homo sapiens	49-55
17560037-2	2007	We report here the identification and characterisation of a novel naturally occurring transition that changes codon 169 from GGC (Gly) to GAC (Asp) in the human Pi class GST, GSTP1.	Glycine	130-133	glutathione S-transferase pi 1	Homo sapiens	175-180
17592510-6	2007	Adhesion assays revealed that baicalein stimulated endothelial cell adhesion to fibronectin and vitronectin, effects blocked by the synthetic peptide Arg-Gly-Asp (RGD).	Glycine	154-157	fibronectin 1	Rattus norvegicus	80-91
17548045-4	2007	The CD23-based substrate, Dabcyl-His-Gly-Asp-Gln-Met-Ala-Gln-Lys-Ser-Lys(Fam)-NH2, is more selective, being hydrolyzed efficiently only by ADAM8 and ADAM10.	Glycine	37-40	ADAM metallopeptidase domain 8	Homo sapiens	139-144
17513176-5	2007	Sequencing of the C1q genes revealed a novel missense mutation (Gly-Arg) in codon 217 of the B chain.	Glycine	64-67	complement C1q A chain	Homo sapiens	18-21
17579031-2	2007	Innate immune responses to RSV are mediated by TLR-4, and the (299)Gly and (399)Ile alleles of the TLR4 gene have been linked epidemiologically with increased severity of RSV disease in children.	Glycine	67-70	toll like receptor 4	Homo sapiens	99-103
17579031-6	2007	Human bronchial epithelial expressing (299)Gly or (399)Ile displayed normal levels of intracellular TLR4 but failed to efficiently translocate the receptor to the cell surface.	Glycine	43-46	toll like receptor 4	Homo sapiens	100-104
17507508-6	2007	CE was used to separate amino acid racemates and to study the selectivity of DAAO and DsdA against D-serine and glycine.	Glycine	112-119	D-amino acid oxidase	Homo sapiens	77-81
17451820-5	2007	), an NMDA receptor glycine-site partial agonist, reversed the enhancement of immobility in the forced swimming test and impairment of CaMKII activation in the PCP-treated mice.	Glycine	20-27	calcium/calmodulin-dependent protein kinase II, delta	Mus musculus	135-141
17517106-11	2007	Immunization with P-Gly induced the production of IFN-gamma [T-helper type 1 (Th1) response] and lowered the production of IL-4 (Th2 response), and a skewed balance towards the Th1 cytokine demonstrated that P-Gly has a modulating ability on Th1/Th2 balance to down-regulate Th2 response.	Glycine	20-23	interleukin 4	Mus musculus	123-127
17517106-11	2007	Immunization with P-Gly induced the production of IFN-gamma [T-helper type 1 (Th1) response] and lowered the production of IL-4 (Th2 response), and a skewed balance towards the Th1 cytokine demonstrated that P-Gly has a modulating ability on Th1/Th2 balance to down-regulate Th2 response.	Glycine	20-23	heart and neural crest derivatives expressed 2	Mus musculus	129-132
17517106-11	2007	Immunization with P-Gly induced the production of IFN-gamma [T-helper type 1 (Th1) response] and lowered the production of IL-4 (Th2 response), and a skewed balance towards the Th1 cytokine demonstrated that P-Gly has a modulating ability on Th1/Th2 balance to down-regulate Th2 response.	Glycine	20-23	heart and neural crest derivatives expressed 2	Mus musculus	246-249
17517106-11	2007	Immunization with P-Gly induced the production of IFN-gamma [T-helper type 1 (Th1) response] and lowered the production of IL-4 (Th2 response), and a skewed balance towards the Th1 cytokine demonstrated that P-Gly has a modulating ability on Th1/Th2 balance to down-regulate Th2 response.	Glycine	20-23	heart and neural crest derivatives expressed 2	Mus musculus	246-249
17369258-7	2007	The nematode proteoglycan modification site in SDN-1 required serine (not threonine), two flanking glycine residues (positions -1 and +1), and either one proximal acidic N-terminal amino acid (positions -4, -3, and -2) or a pair of distal N-terminal acidic amino acids (positions -6 and -5).	Glycine	99-106	Syndecan;putative syndecan	Caenorhabditis elegans	47-52
18634571-5	2007	Simultaneously, the expression of glial amino acid transporters for glycine and glutamate (GlyT1 and GLT1) is reduced on pd 7 and pd 14.	Glycine	68-75	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	91-96
18634571-6	2007	Consistent with a reduced expression of GlyT1 and GLT1, high performance liquid chromatography reveals a net increase in the concentration of glutamate and glycine on pd 7 and pd 14 in tissue from the lumbar spinal cord of neuropathic mice.	Glycine	156-163	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	40-45
17877232-2	2007	Hemoglobin C (Hb C) is a hemoglobin beta variant resulting from a single base mutation at the 6th position of the beta-globin gene leading to the substitution of glycine for glutamic acid.	Glycine	162-169	hemoglobin subunit beta	Homo sapiens	25-40
17164794-6	2007	Isoform SAHH-3 is based on a new polymorphism in exon 3 (377 G&gt;A), leading to the conversion of glycine to arginine at amino-acid position 123.	Glycine	99-106	adenosylhomocysteinase	Homo sapiens	8-12
17138865-3	2007	The final step in the biosynthesis of SP and CGRP is the conversion of their glycine-extended precursors to the active amidated peptide, and this process is catalyzed by sequential action of the enzymes peptidylglycine alpha-monooxygenase (PAM) and peptidylamidoglycolate lyase.	Glycine	77-84	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	203-238
17138865-3	2007	The final step in the biosynthesis of SP and CGRP is the conversion of their glycine-extended precursors to the active amidated peptide, and this process is catalyzed by sequential action of the enzymes peptidylglycine alpha-monooxygenase (PAM) and peptidylamidoglycolate lyase.	Glycine	77-84	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	240-243
16970975-2	2007	Once formed, the molecule can be converted to glycine by alanine-glyoxylate aminotransferase (AGAT).	Glycine	46-53	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	57-92
8913351-4	1996	Our data suggest a model of the pharmacophore of the GlyR that displays significant similarity to that proposed for the glycine binding site of the N-methyl-D-aspartate receptor.	Glycine	120-127	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	148-177
17194506-6	2007	To resolve the behavioral and neurophysiological data, we propose that NPY/Y1 inhibits the spinal release of inhibitory neurotransmitters (GABA and glycine) onto inhibitory neurons, e.g. disinhibition of pain inhibition, resulting in hyporeflexia.	Glycine	148-155	neuropeptide Y	Homo sapiens	71-77
8896810-1	1996	Effect of a mu-opioid agonist (D-Ala2,N-MePhe4,Gly5-ol-enkephalin, DAGO), on glycine (Gly)-induced chloride current (IGly) was investigated in the periaqueductal gray (PAG) neurons acutely dissociated 1-2-week-old Wistar rats by the use of nystatin-perforated patch recording configuration under voltage-clamp condition.	Glycine	77-84	proenkephalin	Rattus norvegicus	55-65
8896810-5	1996	H-89, a protein kinase A (PKA) inhibitor, increased the 10(-5) M Gly response but had little effect on the 10(-4) M Gly response.	Glycine	65-68	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	26-29
8896810-8	1996	The present results suggest that the glycine-induced chloride current is cAMP dependent and is inhibited by PKA, and that the potentiation of the glycine response by DAGO is also cAMP dependent and is due to the inhibition of PKA as that of H-89.	Glycine	37-44	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	108-111
8896810-9	1996	We conclude that the potentiation of glycine response by DAGO is mediated by an inhibition of cAMP-dependent PKA in the PAG neurons.	Glycine	37-44	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	109-112
8794860-4	1996	Mlp60A encodes a protein with a single LIM domain linked to a glycine-rich region.	Glycine	62-69	Muscle LIM protein at 60A	Drosophila melanogaster	0-6
17141957-5	2007	This cleavage was inhibited by Abeta revealing that this cleaving site between Tyr-140 and Gly-141 is involved in the interaction between SAP and Abeta These results suggest that the Abeta-binding site on SAP is larger than it was recently assumed.	Glycine	91-94	amyloid P component, serum	Homo sapiens	138-141
8794860-5	1996	Mlp84B encodes a protein with five tandem LIM-glycine modules.	Glycine	46-53	Muscle LIM protein at 84B	Drosophila melanogaster	0-6
8808922-5	1996	In addition, Hyr1p contained a second domain rich in glycine, serine, and asparagine (79% of 239 residues).	Glycine	53-60	peroxiredoxin HYR1	Saccharomyces cerevisiae S288C	13-18
17141957-5	2007	This cleavage was inhibited by Abeta revealing that this cleaving site between Tyr-140 and Gly-141 is involved in the interaction between SAP and Abeta These results suggest that the Abeta-binding site on SAP is larger than it was recently assumed.	Glycine	91-94	amyloid P component, serum	Homo sapiens	205-208
17085439-0	2007	Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycine-proline-hydroxyproline triplets.	Glycine	159-166	glycoprotein VI platelet	Homo sapiens	121-145
8877818-2	1996	The amplification was achieved using two primers which correspond to TRH progenitor sequence (Lys/Arg-Arg-Gln-His-Pro-Gly-Lys/Arg-Arg).	Glycine	118-121	thyrotropin-releasing hormone L homeolog	Xenopus laevis	69-72
9256503-7	1997	The amount of spectrin breakdown product was positively correlated with the amount of the 98-kDa species of GluR1 after glycine treatment.	Glycine	120-127	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	108-113
18160816-0	2007	SLC40A1 c.1402G--&gt;a results in aberrant splicing, ferroportin truncation after glycine 330, and an autosomal dominant hemochromatosis phenotype.	Glycine	82-89	solute carrier family 40 member 1	Homo sapiens	0-7
9252357-8	1997	Based on the analysis of 67 transglutaminase substrate repeats as present in all known Trappin gene family members from four different mammalian species a consensus sequence could be established: Gly-Gln-Asp-Pro-Val-Lys (GQDPVK).	Glycine	196-199	protein-glutamine gamma-glutamyltransferase 2	Cavia porcellus	28-44
8765374-4	1996	Ten different types of mutations were identified in the MEN 2A/FMTC families (620 Cys--&gt;Arg, 618 Cys--&gt;Ser, Gly, 611 Cys--&gt;Tyr; 634 Cys--&gt;Arg, Tyr, Trp, Phe, Ser, Gly) and all 6 MEN 2B families had a 918 Met--&gt;Thr point mutation.	Glycine	114-117	ret proto-oncogene	Homo sapiens	56-62
11902725-3	1997	SHMT catalyses interconversion of serine and glycine while transferring the resulting one-carbon unit into the C1 pool through methylene tetrahydrofolate.	Glycine	45-52	serine hydroxymethyltransferase 1	Homo sapiens	0-4
17584137-10	2007	Gastrin peptides are derived from progastrin and all have the C-terminal bioactive hexasequence -Tyr (SO4)-Gly-Trp-Met-Asp-Phe-NH2.	Glycine	107-110	gastrin	Homo sapiens	0-7
10191718-1	1997	We have used the method of disequilibrium pattern analysis to examine associations between the threonine-glycine (Thr-Gly) encoding repeat region of the clock gene period (per) of Drosophila melanogaster, and polymorphic sites both upstream and downstream of the repeat, in a number of European fly populations.	Glycine	105-112	period	Drosophila melanogaster	164-170
10191718-1	1997	We have used the method of disequilibrium pattern analysis to examine associations between the threonine-glycine (Thr-Gly) encoding repeat region of the clock gene period (per) of Drosophila melanogaster, and polymorphic sites both upstream and downstream of the repeat, in a number of European fly populations.	Glycine	118-121	period	Drosophila melanogaster	164-170
9114240-4	1997	Similar effects on I(m), g(m), and pHi were revealed on administration of 0.1 or 1 mM glycine.	Glycine	86-93	glucose-6-phosphate isomerase	Rattus norvegicus	35-38
9114240-7	1997	GABA- and glycine-evoked pHi decreases were very similar during recordings with either high- or low-Cl- patch electrodes, although the reversal potential of the accompanying currents differed by approximately 60 mV.	Glycine	10-17	glucose-6-phosphate isomerase	Rattus norvegicus	25-28
9245329-2	1997	Enthalpies and potentially derived fractional charges are determined using 6-31G** basis functions and MP2 level of theory for 216 different configurations of glycine.	Glycine	159-166	tryptase pseudogene 1	Homo sapiens	103-106
9032343-2	1997	Elucidation of the biochemical role of CyPA would be aided by a detailed analysis of the genetic requirements for the formation of the Gag-CyPA complex; previous experiments have demonstrated the requirement for a critical proline and the immediately preceding glycine, located within the capsid domain of Gag, but nothing is known about the necessary CyPA residues.	Glycine	261-268	peptidylprolyl isomerase A	Homo sapiens	39-43
9472410-0	1997	An ultrastructural study of the glycine transporter GLYT2 and its association with glycine in the superficial laminae of the rat spinal dorsal horn.	Glycine	32-39	solute carrier family 6 member 5	Rattus norvegicus	52-57
9472410-1	1997	The glycine transporter GLYT2 is present in axonal boutons throughout the spinal cord, and its laminar distribution matches that of glycine-enriched axons, which are presumed to be glycinergic.	Glycine	4-11	solute carrier family 6 member 5	Rattus norvegicus	24-29
9472410-6	1997	These results confirm that GLYT2 is associated with glycine-enriched axonal boutons in the superficial dorsal horn.	Glycine	52-59	solute carrier family 6 member 5	Rattus norvegicus	27-32
9048335-4	1997	Polystyrene beads coated with Arg-Gly-Asp (RGD)-containing peptide adhere to the surface of sublethally injured MPT cells but not to control, dextrose-treated cells, indicating that the beta 1 integrins present on the apical surface of the cell remain functional.	Glycine	34-37	hemoglobin, beta adult major chain	Mus musculus	186-192
9023299-1	1997	4-Phenyl-3-butenoic acid (PBA) has been shown in vitro to be a turnover-dependent inactivator of peptidylglycine alpha-monooxygenase (PAM), the rate-limiting enzyme involved in the formation of amidated neuropeptides from their glycine-extended precursors.	Glycine	105-112	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	134-137
9110362-1	1997	Single nucleotide substitutions are known to result in a different amino acid at one of four sites in cytochrome P4502C9 (CYP2C9) namely: residue 144: Arg/Cys; residue 358: Tyr/Cys; residue 359: Ile/Leu and residue 417: Gly/Asp.	Glycine	220-223	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	102-120
9110362-1	1997	Single nucleotide substitutions are known to result in a different amino acid at one of four sites in cytochrome P4502C9 (CYP2C9) namely: residue 144: Arg/Cys; residue 358: Tyr/Cys; residue 359: Ile/Leu and residue 417: Gly/Asp.	Glycine	220-223	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	122-128
9027383-0	1997	The glycine site of the NMDA receptor contributes to neurokinin1 receptor agonist facilitation of NMDA receptor agonist-evoked activity in rat dorsal horn neurons.	Glycine	4-11	tachykinin receptor 1	Rattus norvegicus	53-73
9027383-10	1997	These data suggest that activation of the GlyNMDA site (perhaps as a consequence of glycine release or modification of its influence by intracellular signalling cascades) is an essential component of the means by which NK1 receptor activation results in facilitated responsiveness of dorsal horn neurons towards NMDA receptor agonists.	Glycine	84-91	tachykinin receptor 1	Rattus norvegicus	219-231
9003420-1	1997	Glutathione is essential for a variety of cellular functions, and is synthesized from gamma-glutamylcysteine and glycine by the action of glutathione synthase (EC 6.3.2.3).	Glycine	113-120	glutathione synthetase	Homo sapiens	138-158
18475769-0	1997	Ternary Complexes of cis-(NH(3))(2)PtCl(2) (cis-DDP) With Guanosine (guo), Cytidine (cyd) and the Aminoacids Glycine (gly), L-Alanine (ala), L-2-Aminobutyric Acid (2-aba), L-Norvaline (nval) and L-Norleucine (nleu).	Glycine	109-116	translocase of inner mitochondrial membrane 8A	Homo sapiens	48-51
18475769-0	1997	Ternary Complexes of cis-(NH(3))(2)PtCl(2) (cis-DDP) With Guanosine (guo), Cytidine (cyd) and the Aminoacids Glycine (gly), L-Alanine (ala), L-2-Aminobutyric Acid (2-aba), L-Norvaline (nval) and L-Norleucine (nleu).	Glycine	118-121	translocase of inner mitochondrial membrane 8A	Homo sapiens	48-51
18475815-0	1997	Ternary Complexes of cis-(NH(3))(2)PtCl(2) (cis-DDP) With Guanosine (guo), Cytidine (cyd) and the Aminoacids Glycine (gly), L-Alanine (ala), L-2-Aminobutyric Acid (2-aba), L-Norvaline (nval) and L-Norleucine (nleu).	Glycine	109-116	translocase of inner mitochondrial membrane 8A	Homo sapiens	48-51
18475815-0	1997	Ternary Complexes of cis-(NH(3))(2)PtCl(2) (cis-DDP) With Guanosine (guo), Cytidine (cyd) and the Aminoacids Glycine (gly), L-Alanine (ala), L-2-Aminobutyric Acid (2-aba), L-Norvaline (nval) and L-Norleucine (nleu).	Glycine	118-121	translocase of inner mitochondrial membrane 8A	Homo sapiens	48-51
8943296-2	1996	Replacement of a highly conserved glycine residue on transmembrane (TM) helix 3 of bovine rhodopsin (Gly121) by amino acid residues with larger side chains causes a progressive blue-shift in the lambdamax value of the pigment, a decrease in thermal stability, and an increase in reactivity with hydroxylamine.	Glycine	34-41	rhodopsin	Bos taurus	90-99
8957102-3	1996	Among these, the hnRNP-A/B proteins form a subgroup of highly related proteins: their N-terminal halves consist of two adjacent RNA-binding domains, whereas the C-terminal halves contain almost 50% glycine residues.	Glycine	198-205	heterogeneous nuclear ribonucleoprotein A/B	Homo sapiens	17-26
8858933-2	1996	The glycine site antagonist 5,7-[3H]dichlorokynurenic acid labeled a single high-affinity site (KD = 29.6 +/- 6 nM; Bmax = 19.4 +/- 1.6 pmol/mg of protein) in membranes derived from COS cells electroporated with NR1-1a.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	212-215
8858933-6	1996	Although expression of NR1-1a is sufficient to reconstitute a glycine binding site with wild-type affinity for antagonists in COS cells, recombinant homomeric NR1-1a receptors do not display properties that are characteristic of native NMDA receptors, such as permeability to Ca2+ and channel occupancy by MK-801, when expressed in this mammalian cell line.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	23-26
8908597-6	1996	Identical point mutations were detected in the transmembrane domain of p75NTR in the two melanoma lines with reduced p75NTR protein expression, which resulted in the substitution of the uncharged amino acid Gly for the negatively-charged Asp.	Glycine	207-210	nerve growth factor receptor	Homo sapiens	71-77
8908597-6	1996	Identical point mutations were detected in the transmembrane domain of p75NTR in the two melanoma lines with reduced p75NTR protein expression, which resulted in the substitution of the uncharged amino acid Gly for the negatively-charged Asp.	Glycine	207-210	nerve growth factor receptor	Homo sapiens	117-123
8816444-0	1996	A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3.	Glycine	56-63	eukaryotic translation initiation factor 4B	Homo sapiens	80-111
8816444-0	1996	A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3.	Glycine	56-63	eukaryotic translation initiation factor 4B	Homo sapiens	113-118
8816444-6	1996	A region rich in aspartic acid, arginine, tyrosine, and glycine, termed the DRYG domain, is sufficient for self-association of eIF4B, both in vitro and in vivo, and for interaction with the p170 subunit of eIF3.	Glycine	56-63	eukaryotic translation initiation factor 4B	Homo sapiens	127-132
8890956-4	1996	One of the 40 DMBA-induced mammary tumors had a p53 mutation, a single-base substitution (AGC--&gt;GGC) at codon 307, resulting in an amino-acid change from Ser to Gly.	Glycine	164-167	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	48-51
8810903-1	1996	Glycine N-methyltransferase (GNMT) from rat liver is a tetrameric enzyme with 292 amino acid residues in each identical subunit and catalyzes the S-adenosylmethionine (AdoMet) dependent methylation of glycine to form sarcosine.	Glycine	201-208	glycine N-methyltransferase	Rattus norvegicus	0-27
8810903-1	1996	Glycine N-methyltransferase (GNMT) from rat liver is a tetrameric enzyme with 292 amino acid residues in each identical subunit and catalyzes the S-adenosylmethionine (AdoMet) dependent methylation of glycine to form sarcosine.	Glycine	201-208	glycine N-methyltransferase	Rattus norvegicus	29-33
8947586-6	1996	DNA sequence analysis revealed a mutation in the ligand binding region of retinoic acid receptor alpha in the HL-60/RA cells in which a glycine was replaced by an aspartic acid.	Glycine	136-143	retinoic acid receptor alpha	Homo sapiens	74-102
8702765-1	1996	The Arg-Gly-Asp (RGD) sequence within the third complementarity-determining region (CDR3) of the heavy chain (H3) is responsible for the binding of the recombinant murine Fab molecules, AP7 and PAC1.1, to the platelet integrin alphaIIbbeta3.	Glycine	8-11	cerebellar degeneration-related 3	Mus musculus	84-88
8702765-1	1996	The Arg-Gly-Asp (RGD) sequence within the third complementarity-determining region (CDR3) of the heavy chain (H3) is responsible for the binding of the recombinant murine Fab molecules, AP7 and PAC1.1, to the platelet integrin alphaIIbbeta3.	Glycine	8-11	dual specificity phosphatase 2	Mus musculus	194-198
8698354-4	1996	The deletions reported here would result in severe disruptions of the ATM gene product by leading either to a protein truncation (a 4-bp deletion) or the loss of stretches of 53 and 58 amino acids (a 159-bp deletion and a 174-bp deletion, respectively); whereas the base substitution would lead to an amino acid change from a highly conserved glycine to an arginine residue.	Glycine	343-350	ATM serine/threonine kinase	Homo sapiens	70-73
8776903-7	1996	The deduced amino acid (427 residues) sequence from the short transcript has strong homology to the animal U1-70K protein and contains an RNA recognition motif, a glycine hinge, and an arginine-rich region characteristic of the animal U1-70K protein.	Glycine	163-170	U1 small nuclear ribonucleoprotein-70K	Arabidopsis thaliana	107-113
8662894-5	1996	In all individuals with the FUT6 missense mutation Gly-739 --&gt; Ala in double dose, no fucosylation of alpha1-acid glycoprotein was found.	Glycine	51-54	fucosyltransferase 6	Homo sapiens	28-32
8781786-1	1996	Glycine conjugation of benzoic acid is catalyzed by the mitochondrial enzymes benzoyl-coenzyme A(CoA) synthetase and benzoyl-CoA: glycine N-acyltransferase and requires ATP, CoA, and glycine as cosubstrates.	Glycine	0-7	glycine-N-acyltransferase	Rattus norvegicus	130-155
8632144-5	1996	Glycine site agonists showed a 2.6-5.4-fold higher affinity for NR1a/NR2B receptors.	Glycine	0-7	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	69-73
8752681-0	1996	Genetic basis of Bart"s syndrome: a glycine substitution mutation in the type VII collagen gene.	Glycine	36-43	barttin CLCNK type accessory subunit beta	Homo sapiens	17-21
8626673-4	1996	As judged by proteolysis sensitivity, DnaJ is composed of three separate regions, a 9-kDa NH2-terminal domain, a 30-kDa COOH-terminal domain, and a protease-sensitive glycine- and phenylalanine-rich (G/F-rich) segment of 30 amino acids that serves as a flexible linker between the two domains.	Glycine	167-174	DnaJ	Escherichia coli	38-42
8615045-7	1996	The results of our analyses show that two glycine residues (G10 and G13) located within the sequence FLGFLG in the middle of the fusion peptide are critical for syncytium formation and for the establishment of a productive infection, whereas other glycine residues (G3, G5, and G20) are more permissive to substitutions.	Glycine	42-49	chromosome 3 open reading frame 18	Homo sapiens	278-281
9004490-0	1996	The tubulin gene family of Paramecium: characterization and expression of the alpha PT1 and alpha PT2 genes which code for alpha-tubulins with unusual C-terminal amino acids, GLY and ALA.	Glycine	175-178	zinc finger protein 77	Homo sapiens	84-87
9004490-4	1996	We show that P tetraurelia possesses four alpha- and three beta-genes and we report the cloning and sequencing of two intronless alpha-genes, alpha PT1 and alpha PT2, which code for very similar polypeptides, differing only by their unusual C-terminal amino acids, respectively GLY and ALA.	Glycine	278-281	zinc finger protein 77	Homo sapiens	148-165
8774538-4	1996	Like many members of the integrin family, alpha v beta 3 recognizes the sequence Arg-Gly-Asp (RGD) in its ligands, and other molecules that contain this sequence will complete with the natural ligands (such as vitronectin) for binding.	Glycine	85-88	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	50-56
8690320-9	1996	By comparing the coding area of the Duffy gene in 28 Duffy positive individuals, we elucidated that one base change that results in an amino acid substitution (GAT(Asp44)--&gt;GGT(Gly)) is in accordance with the Fya/Fyb polymorphism.	Glycine	180-183	FYN binding protein 1	Homo sapiens	216-219
8839980-1	1996	Glycyl-tRNA synthetase, a class II aminoacyl-tRNA synthetase, catalyzes the synthesis of glycyl-tRNA, which is required to insert glycine into proteins.	Glycine	130-137	glycyl-tRNA synthetase 1	Homo sapiens	0-60
8725286-4	1996	Inhibition of fibronectin matrix formation by the inclusion of Arg-Gly-Asp-containing peptides, which compete with fibronectin for binding to the cell surface alpha 5 beta 1 integrin receptors, abolished the proliferation effects of FGF-2.	Glycine	67-70	fibronectin 1	Gallus gallus	14-25
8725286-4	1996	Inhibition of fibronectin matrix formation by the inclusion of Arg-Gly-Asp-containing peptides, which compete with fibronectin for binding to the cell surface alpha 5 beta 1 integrin receptors, abolished the proliferation effects of FGF-2.	Glycine	67-70	fibronectin 1	Gallus gallus	115-126
8675302-5	1996	We found that a single amino acid substitution (glycine to aspartic acid) in the putative third outer loop greatly reduced Rck-mediated serum resistance and eukaryotic cell invasion.	Glycine	48-55	resistance to complement killing	Salmonella enterica subsp. enterica serovar Typhimurium	123-126
8667254-4	1996	The association rate of [3H]dextrorphan with its binding site in area stratum radiatum of CA1 is accelerated by the addition of glycine and glutamate.	Glycine	128-135	carbonic anhydrase 1	Rattus norvegicus	90-93
8636991-1	1996	The ion channel properties of human annexin V, a calcium- and phospholipid-binding protein of the annexin family, have been structurally and functionally investigated by analysing the mutant Glu112 --&gt;Gly.	Glycine	204-207	annexin A5	Homo sapiens	36-45
8722626-7	1996	The effect of fibronectin was inhibited by hexapeptides that contained the integrin-recognizing Arg-Gly-Asp sequence.	Glycine	100-103	fibronectin 1	Mus musculus	14-25
8859906-2	1996	Heterologous expression of the human alpha-1 subunit generated functional glycine-gated channels with properties typical of native receptors.	Glycine	74-81	adrenoceptor alpha 1D	Homo sapiens	37-44
8615824-9	1996	Leu-17 and Gly-20 of CP 2, Ser-17, Ala-19, Glu-21, Asp-23 and Glu-25 of CP 3 and Lys-18 of CP 4 are all conserved between the three species.	Glycine	11-14	ceruloplasmin	Homo sapiens	21-25
8815211-13	1996	Channels in which the NR1 N-site asparagine was replaced by the smaller glycine (G), NR1(N598G)-NR2A, showed the largest increase in pore size of all sites examined in either subunit.	Glycine	72-79	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	85-88
8785300-1	1996	Actin labeled at Gln-41 with dansyl ethylenediamine (DED) via transglutaminase reaction was used for monitoring the interaction of myosin subfragment 1 (S1) with the His-40-Gly-42 site in the 38-52 loop on F-actin.	Glycine	173-176	myosin heavy chain 14	Homo sapiens	131-137
8786078-1	1996	The conversion of serine and tetrahydrofolate to glycine and 5,10 methylene tetrahydrofolate by serine hydroxymethyltransferase (SHMT, EC 2.1.2.1) is the major route for the provision of one-carbon units for biosynthetic reactions.	Glycine	49-56	serine hydroxymethyltransferase 1	Homo sapiens	96-127
8786078-1	1996	The conversion of serine and tetrahydrofolate to glycine and 5,10 methylene tetrahydrofolate by serine hydroxymethyltransferase (SHMT, EC 2.1.2.1) is the major route for the provision of one-carbon units for biosynthetic reactions.	Glycine	49-56	serine hydroxymethyltransferase 1	Homo sapiens	129-133
8554252-9	1996	RESULTS: Through DNA sequencing, we detected a mutation at amino acid residue 188 of lipoprotein lipase (LPL), reflecting product from one allele of the LPL gene in which a glutamine residue was substituted for a glycine (gly 188--&gt;glu).	Glycine	213-220	lipoprotein lipase	Homo sapiens	85-103
8554252-9	1996	RESULTS: Through DNA sequencing, we detected a mutation at amino acid residue 188 of lipoprotein lipase (LPL), reflecting product from one allele of the LPL gene in which a glutamine residue was substituted for a glycine (gly 188--&gt;glu).	Glycine	213-220	lipoprotein lipase	Homo sapiens	105-108
8554252-9	1996	RESULTS: Through DNA sequencing, we detected a mutation at amino acid residue 188 of lipoprotein lipase (LPL), reflecting product from one allele of the LPL gene in which a glutamine residue was substituted for a glycine (gly 188--&gt;glu).	Glycine	213-220	lipoprotein lipase	Homo sapiens	153-156
8554252-9	1996	RESULTS: Through DNA sequencing, we detected a mutation at amino acid residue 188 of lipoprotein lipase (LPL), reflecting product from one allele of the LPL gene in which a glutamine residue was substituted for a glycine (gly 188--&gt;glu).	Glycine	213-216	lipoprotein lipase	Homo sapiens	85-103
8554252-9	1996	RESULTS: Through DNA sequencing, we detected a mutation at amino acid residue 188 of lipoprotein lipase (LPL), reflecting product from one allele of the LPL gene in which a glutamine residue was substituted for a glycine (gly 188--&gt;glu).	Glycine	213-216	lipoprotein lipase	Homo sapiens	105-108
8554252-9	1996	RESULTS: Through DNA sequencing, we detected a mutation at amino acid residue 188 of lipoprotein lipase (LPL), reflecting product from one allele of the LPL gene in which a glutamine residue was substituted for a glycine (gly 188--&gt;glu).	Glycine	213-216	lipoprotein lipase	Homo sapiens	153-156
8554252-12	1996	This heterozygous LPL mutation, gly 188--&gt;glu, is prevalent in certain ethnic groups and may be a common cause of pancreatitis associated with pregnancy.	Glycine	32-35	lipoprotein lipase	Homo sapiens	18-21
9062068-2	1996	Drastic changes in the CD and fluorescence spectra of oxytocin [cyclo(Cys1-Tyr2-Ile3-Gln4-Asn5-Cys6)-Pro7-Leu8-Gly 9-NH2] occur on binding Ca2+ in trifluoroethanol (Ananthanarayanan and Brimble, preceding paper).	Glycine	111-114	cystin 1	Homo sapiens	70-74
9062068-2	1996	Drastic changes in the CD and fluorescence spectra of oxytocin [cyclo(Cys1-Tyr2-Ile3-Gln4-Asn5-Cys6)-Pro7-Leu8-Gly 9-NH2] occur on binding Ca2+ in trifluoroethanol (Ananthanarayanan and Brimble, preceding paper).	Glycine	111-114	selectin L	Homo sapiens	106-110
8717357-6	1996	Glycine-gated currents of alpha 1/beta GlyRs were 17-fold less sensitive than homomeric alpha 1 GlyRs to the antagonists picrotoxin, picrotoxinin and picrotin, providing clear evidence that heteromeric alpha 1/beta GlyRs were expressed.	Glycine	0-7	glycine receptor alpha 1	Homo sapiens	26-44
8717357-6	1996	Glycine-gated currents of alpha 1/beta GlyRs were 17-fold less sensitive than homomeric alpha 1 GlyRs to the antagonists picrotoxin, picrotoxinin and picrotin, providing clear evidence that heteromeric alpha 1/beta GlyRs were expressed.	Glycine	0-7	glycine receptor alpha 1	Homo sapiens	202-220
8594879-9	1995	Pretreatment of tubules with glycine before hypoxia blocked this release of PLA2 but not activation of soluble PLA2 activity.	Glycine	29-36	phospholipase A2 group IB	Rattus norvegicus	76-80
8825881-3	1995	Sequencing analysis revealed a three nucleotide deletion at codon 10 leading to a deletion of a glycine residue, which has been conserved in the myosin gene from birds to humans.	Glycine	96-103	myosin heavy chain 14	Homo sapiens	145-151
7586199-8	1995	These base substitutions induced respectively glycine to cysteine (G1) or valine (G2) change in the P21ras protein.	Glycine	46-53	HRas proto-oncogene, GTPase	Homo sapiens	100-106
8586061-1	1995	Glycine N-methyltransferase from rabbit, human, rat and pig livers was separated by isoelectric focusing and a specific functional staining method was developed through the detection of sarcosine produced from the methylation of glycine.	Glycine	229-236	glycine N-methyltransferase	Oryctolagus cuniculus	0-27
7589073-3	1995	By the use of glycine-based designer peptides for primary induction of CTL in vitro, we have identified two sub-epitopes on individual position 7-haptenated peptides that form two TcR contact points and which can be independently recognized by cloned CTL.	Glycine	14-21	T cell receptor alpha variable 6-3	Mus musculus	180-183
7476899-3	1995	Ethanol dose-response analysis revealed enhanced inhibitory efficacy of ethanol in the presence of subsaturating glycine concentrations at the NR1/NR2A, NR1/NR2C, and NR1/NR2D receptors.	Glycine	113-120	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	143-146
7476899-3	1995	Ethanol dose-response analysis revealed enhanced inhibitory efficacy of ethanol in the presence of subsaturating glycine concentrations at the NR1/NR2A, NR1/NR2C, and NR1/NR2D receptors.	Glycine	113-120	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	153-156
7476899-3	1995	Ethanol dose-response analysis revealed enhanced inhibitory efficacy of ethanol in the presence of subsaturating glycine concentrations at the NR1/NR2A, NR1/NR2C, and NR1/NR2D receptors.	Glycine	113-120	glutamate receptor, ionotropic, N-methyl D-aspartate 2C L homeolog	Xenopus laevis	157-161
7476899-3	1995	Ethanol dose-response analysis revealed enhanced inhibitory efficacy of ethanol in the presence of subsaturating glycine concentrations at the NR1/NR2A, NR1/NR2C, and NR1/NR2D receptors.	Glycine	113-120	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	153-156
7476899-6	1995	Glycine reversal of ethanol inhibition suggested that ethanol might lower the affinity of glycine for the NMDA receptor and thereby decrease response magnitude.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	106-119
7583235-0	1995	Glycine-induced CA1 excitotoxicity in the rat hippocampal slice.	Glycine	0-7	carbonic anhydrase 1	Rattus norvegicus	16-19
7583235-1	1995	We evaluated the effects of glycine exposure upon CA1 evoked response in the rat hippocampal slice.	Glycine	28-35	carbonic anhydrase 1	Rattus norvegicus	50-53
7583235-2	1995	Exposure to 10 mM glycine for 16 min, produced rapid neuronal firing and increased orthodromic population spike (PS), followed by loss of CA1 neural transmission.	Glycine	18-25	carbonic anhydrase 1	Rattus norvegicus	138-141
7642803-11	1995	Those data, the present results, and other molecular, biochemical, and anatomical studies of gephyrin in the central nervous system (CNS) are consistent with two hypotheses: 1) Postsynaptic gephyrin is associated with GABAA receptors in the membranes of sympathetic preganglionic neurons, and 2) GABA+/gephyrin+ associations do not necessarily predict colocalization of GABA and glycine within single boutons synapsing on sympathetic preganglionic somata and dendrites.	Glycine	379-386	gephyrin	Homo sapiens	190-198
7642803-11	1995	Those data, the present results, and other molecular, biochemical, and anatomical studies of gephyrin in the central nervous system (CNS) are consistent with two hypotheses: 1) Postsynaptic gephyrin is associated with GABAA receptors in the membranes of sympathetic preganglionic neurons, and 2) GABA+/gephyrin+ associations do not necessarily predict colocalization of GABA and glycine within single boutons synapsing on sympathetic preganglionic somata and dendrites.	Glycine	379-386	gephyrin	Homo sapiens	190-198
7550111-4	1995	Similar enhancement was observed when the macrophages were plated on a substrate pre-coated with Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) peptide, an adhesive sequence of FN involved in binding to the cells, but not with the control Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) peptide.	Glycine	97-100	fibronectin 1	Mus musculus	163-165
7550111-4	1995	Similar enhancement was observed when the macrophages were plated on a substrate pre-coated with Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) peptide, an adhesive sequence of FN involved in binding to the cells, but not with the control Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) peptide.	Glycine	105-108	fibronectin 1	Mus musculus	163-165
7550111-4	1995	Similar enhancement was observed when the macrophages were plated on a substrate pre-coated with Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) peptide, an adhesive sequence of FN involved in binding to the cells, but not with the control Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) peptide.	Glycine	105-108	fibronectin 1	Mus musculus	163-165
7666148-9	1995	The increase in chloride conductance (gCl-) evoked by glycine was time and voltage dependent.	Glycine	54-61	germ cell-less, spermatogenesis associated	Danio rerio	38-41
7666148-13	1995	The basis of the voltage sensitivity of glycine-evoked gCl- was first analyzed by measuring the relative changes in the total open probability (NPo) of glycine-activated channels with voltage.	Glycine	40-47	germ cell-less, spermatogenesis associated	Danio rerio	55-58
7667186-1	1995	PURPOSE: An efficient freeze-drying cycle for recombinant human interleukin-1 receptor antagonist (rhIL-1ra) formulations, which contained glycine and sucrose as excipients, was developed.	Glycine	139-146	interleukin 1 receptor antagonist	Homo sapiens	64-97
7761465-1	1995	Inositol polyphosphate 1-phosphatase, inositol monophosphate phosphatase, and fructose 1,6-bisphosphatase share a sequence motif, Asp-Pro-(Ile or Leu)-Asp-(Gly or Ser)-(Thr or Ser), that has been shown by crystallographic and mutagenesis studies to bind metal ions and participate in catalysis.	Glycine	156-159	inositol polyphosphate-1-phosphatase	Homo sapiens	0-36
7784433-0	1995	Conformational study of the Thr-Gly repeat in the Drosophila clock protein, PERIOD.	Glycine	32-35	period	Drosophila melanogaster	76-82
7784433-1	1995	Recent results with the Drosophila melanogaster period gene suggest that the apparently conserved repetitive motif (Thr-Gly)n encoded by this gene may play an important role in the temperature compensation of the circadian clock.	Glycine	120-123	period	Drosophila melanogaster	48-54
7633596-4	1995	N-Terminal sequencing revealed IGF II and an IGF II variant in which Ser29 was replaced by the tetrapeptide Arg-Leu-Pro-Gly.	Glycine	120-123	insulin like growth factor 2	Homo sapiens	45-51
7721888-6	1995	Transfection of the full length human cDNA into cells lacking FPGS restored their ability to grow in the absence of glycine, a product of mitochondrial folate metabolism, as well as of thymidine and purines.	Glycine	116-123	folylpolyglutamate synthase	Homo sapiens	62-66
7542253-7	1995	GRGDS (gly-arg-gly-asp-ser) peptides inhibited cell adhesion to intact GST-OPN, as well as to fibronectin and vitronectin.	Glycine	7-10	fibronectin 1	Mus musculus	94-105
7542253-7	1995	GRGDS (gly-arg-gly-asp-ser) peptides inhibited cell adhesion to intact GST-OPN, as well as to fibronectin and vitronectin.	Glycine	15-18	fibronectin 1	Mus musculus	94-105
7708669-6	1995	Based on this structural evidence, H-2Kb has at least two submotifs: one with Tyr at P5 (or P6 for nonamer peptides) and a small residue at P2 (i.e., Ala or Gly) and another with Phe at P5 and a medium-sized hydrophobic residue at P2 (i.e., Ile).	Glycine	157-160	histocompatibility 2, K1, K region	Mus musculus	35-40
7861131-5	1995	The results indicate that GLYT2 is involved in the termination of glycine neurotransmission accompanying the glycine receptor at the classic inhibitory system in the hindbrain.	Glycine	66-73	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	26-31
7533293-2	1995	We confirm that wa-2 is a point mutation (T--&gt;G resulting in a valine--&gt;glycine substitution at residue 743) in the gene encoding the epidermal growth factor (EGF) receptor.	Glycine	78-85	epidermal growth factor receptor	Mus musculus	16-20
7876092-3	1995	One sequence, GYENPTY, is related to the low density lipoprotein receptor internalization signal, FDNPVY, but also involves a critical glycine residue; the other, YTSI, conforms to the 4-residue tyrosine-based internalization signal consensus sequence.	Glycine	135-142	low density lipoprotein receptor	Homo sapiens	41-73
7833467-11	1995	By comparing the coding area of the gpFy gene in 28 Duffy-positive individuals, we elucidated that one base change that results in an amino acid substitution [GA-T(Asp44)-->GGT(Gly)] is in accordance with the Fya/Fyb polymorphism.	Glycine	177-180	FYN binding protein 1	Homo sapiens	213-216
7540635-6	1995	We now report that the Arg-Gly-Asp-mimetics specifically inhibited the binding of murine T cells to fibronectin, but did not affect the proliferative response of these cells in vitro.	Glycine	27-30	fibronectin 1	Mus musculus	100-111
7731166-2	1995	By using PCR-amplification and direct sequencing we identified a novel mutation involving a deletion of the last two bases in the codon GGA for Glycine-1479 in exon 47 of the COL4A5 gene in a patient with a juvenile form of X-linked Alport syndrome with deafness.	Glycine	144-151	collagen type IV alpha 5 chain	Homo sapiens	175-181
8978778-0	1996	Cloning, expression, and mapping of CKAPI, which encodes a putative cytoskeleton-associated protein containing a CAP-GLY domain.	Glycine	117-120	tubulin folding cofactor B	Homo sapiens	36-41
8978778-3	1996	The cDNA, designated CKAPI (for cytoskeleton-associated protein I, glycine motif) contained an open reading frame of 579 nucleotides encoding 193 amino acids.	Glycine	67-74	tubulin folding cofactor B	Homo sapiens	21-26
8978778-3	1996	The cDNA, designated CKAPI (for cytoskeleton-associated protein I, glycine motif) contained an open reading frame of 579 nucleotides encoding 193 amino acids.	Glycine	67-74	tubulin folding cofactor B	Homo sapiens	32-65
8979267-1	1996	The partially modified retro- and retro-inverso peptides of the Arg-Gly Asp (RGD) sequence of fibronectin, in which the direction of the Arg residue is reversed and/or the chirality of the amino acid residue is inverted, i.e., mainly R(rev)-COCH2CO-D and DR(rev)-COCH2CO-D, have been synthesized to examine their antimetastatic effects in murine lung or liver metastasis models, as well as their inhibitory effect on tumor cell invasion in vitro.	Glycine	68-71	fibronectin 1	Mus musculus	94-105
8719885-5	1995	Adding the RGD peptide, Gly-Arg-Gly-Glu-Ser-Pro to the medium of sparsely plated cells resulted in rapid reductions in cell spreading concomitant with dose-dependent decreases in ornithine decarboxylase activity and putrescine uptake.	Glycine	24-27	ornithine decarboxylase 1	Rattus norvegicus	179-202
8719885-5	1995	Adding the RGD peptide, Gly-Arg-Gly-Glu-Ser-Pro to the medium of sparsely plated cells resulted in rapid reductions in cell spreading concomitant with dose-dependent decreases in ornithine decarboxylase activity and putrescine uptake.	Glycine	32-35	ornithine decarboxylase 1	Rattus norvegicus	179-202
7837791-2	1995	BACKGROUND: Osteopontin (OPN) is a phosphorylated glycoprotein that contains a functional Gly-Arg-Gly-Asp-Ser (GRGDS) cell-binding sequence.	Glycine	90-93	secreted phosphoprotein 1	Homo sapiens	12-23
7837791-2	1995	BACKGROUND: Osteopontin (OPN) is a phosphorylated glycoprotein that contains a functional Gly-Arg-Gly-Asp-Ser (GRGDS) cell-binding sequence.	Glycine	90-93	secreted phosphoprotein 1	Homo sapiens	25-28
17116739-7	2007	Acnat1 is mainly expressed in liver and kidney, and the gene is localized in a gene cluster, together with two further acyltransferases, one of which conjugates bile acids to glycine and taurine.	Glycine	175-182	acyl-coenzyme A amino acid N-acyltransferase 1	Mus musculus	0-6
7732609-3	1995	However, serial blood and CSF amino-acid analyses demonstrated elevated glycine levels.	Glycine	72-79	colony stimulating factor 2	Homo sapiens	26-29
7732609-4	1995	Serum and CSF glycine levels were 1949 mumol/L and 415.5 mumol/L, respectively.	Glycine	14-21	colony stimulating factor 2	Homo sapiens	10-13
17166179-3	2007	CNBP is mainly conformed by seven retroviral Cys-Cys-His-Cys zinc-knuckles and a glycine/arginine rich region box.	Glycine	81-88	CCHC-type zinc finger, nucleic acid binding protein a	Danio rerio	0-4
7528281-2	1994	Peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes the synthesis of the biologically essential C-terminal amide from a glycine-extended precursor peptide.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	47-50
7528281-7	1994	The compound series also exhibited potent inhibition of PAM in rat dorsal root ganglion cells as demonstrated by a dose-dependent increase in the substance P-Gly/substance P ratio.	Glycine	158-161	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	56-59
7490766-3	1995	In this context, we have synthesized the peptides corresponding to the leucine zipper domains of Max and c-Myc with a N-terminal Cys-Gly-Gly linker and studied their dimerization behavior using reversed-phase HPLC and CD spectroscopy.	Glycine	133-136	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	105-110
17010310-2	2006	Apobec1 is regulated by ACF (Apobec1 complementation factor) and hnRNPQ, which contains an N-terminal "acidic domain" (AcD) of unknown function, three RNA recognition motifs, and an Arg/Gly-rich region.	Glycine	186-189	apolipoprotein B mRNA editing enzyme catalytic subunit 1	Homo sapiens	0-7
7592916-2	1995	We have identified a novel phosphoserine/threonine/tyrosine-binding protein (STYX) that is related in amino acid sequence to dsPTPases, except for the substitution of Gly for Cys in the conserved dsPTPase catalytic loop (HCXXGXXR(S/T)).	Glycine	167-170	serine/threonine/tyrosine interaction protein	Mus musculus	77-81
7595479-0	1995	Modulation of a recombinant glycine transporter (GLYT1b) by activation of protein kinase C. Treatment of human embryonic kidney cells (HEK 293 cells) expressing the mouse glycine transporter 1 (GLYT1b) with the protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) decreased specific [3H]glycine uptake.	Glycine	28-35	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	171-192
7696183-4	1994	However, there were some properties of Rak that are distinct from Src-like kinases: (a) expression of Rak was predominantly in epithelial-derived cell lines and tissues, especially normal liver and kidney, and cell lines of breast and colon origin; (b) Rak does not harbor the NH2-terminal glycine essential for myristylation and membrane localization; and (c) Rak possesses a putative bipartite nuclear localization signal in the SH2 domain, and subcellular fractionation studies revealed that p54rak resides predominantly in the nucleus.	Glycine	290-297	fyn related Src family tyrosine kinase	Homo sapiens	39-42
7696183-4	1994	However, there were some properties of Rak that are distinct from Src-like kinases: (a) expression of Rak was predominantly in epithelial-derived cell lines and tissues, especially normal liver and kidney, and cell lines of breast and colon origin; (b) Rak does not harbor the NH2-terminal glycine essential for myristylation and membrane localization; and (c) Rak possesses a putative bipartite nuclear localization signal in the SH2 domain, and subcellular fractionation studies revealed that p54rak resides predominantly in the nucleus.	Glycine	290-297	fyn related Src family tyrosine kinase	Homo sapiens	102-105
7696183-4	1994	However, there were some properties of Rak that are distinct from Src-like kinases: (a) expression of Rak was predominantly in epithelial-derived cell lines and tissues, especially normal liver and kidney, and cell lines of breast and colon origin; (b) Rak does not harbor the NH2-terminal glycine essential for myristylation and membrane localization; and (c) Rak possesses a putative bipartite nuclear localization signal in the SH2 domain, and subcellular fractionation studies revealed that p54rak resides predominantly in the nucleus.	Glycine	290-297	fyn related Src family tyrosine kinase	Homo sapiens	102-105
7696183-4	1994	However, there were some properties of Rak that are distinct from Src-like kinases: (a) expression of Rak was predominantly in epithelial-derived cell lines and tissues, especially normal liver and kidney, and cell lines of breast and colon origin; (b) Rak does not harbor the NH2-terminal glycine essential for myristylation and membrane localization; and (c) Rak possesses a putative bipartite nuclear localization signal in the SH2 domain, and subcellular fractionation studies revealed that p54rak resides predominantly in the nucleus.	Glycine	290-297	fyn related Src family tyrosine kinase	Homo sapiens	102-105
17010310-2	2006	Apobec1 is regulated by ACF (Apobec1 complementation factor) and hnRNPQ, which contains an N-terminal "acidic domain" (AcD) of unknown function, three RNA recognition motifs, and an Arg/Gly-rich region.	Glycine	186-189	synaptotagmin binding cytoplasmic RNA interacting protein	Homo sapiens	65-71
17075061-1	2006	We have used fluorescence correlation spectroscopy measurements to quantify the hydrodynamic sizes of monomeric polyglutamine as a function of chain length (N) by measuring the scaling of translational diffusion times (tau(D)) for the peptide series (Gly)-(Gln)(N)-Cys-Lys(2) in aqueous solution.	Glycine	251-254	microtubule associated protein tau	Homo sapiens	219-222
7527413-14	1994	We conclude that the aspartic acid578--&gt;glycine mutation in the LH/CGR has arisen in the Japanese population and is the cause of a sporadic case of male-limited precocious puberty.	Glycine	43-50	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	67-73
9223012-1	1995	The cyclic octapeptide cyclo[-Pro1-Pro-Phe-Phe-Ac6c-Ile-ala-Val8-] [C8-Ac6c], containing the Pro1-Pro-Phe-Phe sequence, followed by a bulky helicogenic C alpha,alpha-dialkylated glycine residue Ac6c [1-aminocyclohexane-1-carboxylic acid), and a D-Ala residue at position 7 has been synthesized.	Glycine	178-185	lamin A/C	Homo sapiens	30-34
16738862-2	2006	AMI1 is part of a small isogene family comprising seven members in A. thaliana encoding proteins which share a conserved glycine- and serine-rich amidase-signature.	Glycine	121-128	amidase 1	Arabidopsis thaliana	0-4
7628866-4	1995	Ras alterations were detected in the H-ras gene in 3 tumors, 2 of which harbored a codon-13 (Gly--&gt;Arg) and one a codon-12 (Gly--&gt;Ser) point mutation.	Glycine	93-96	HRas proto-oncogene, GTPase	Homo sapiens	37-42
7628866-4	1995	Ras alterations were detected in the H-ras gene in 3 tumors, 2 of which harbored a codon-13 (Gly--&gt;Arg) and one a codon-12 (Gly--&gt;Ser) point mutation.	Glycine	127-130	HRas proto-oncogene, GTPase	Homo sapiens	37-42
7762551-3	1995	The glycine in this position is highly conserved in EGF-like domains of FBN1 and other proteins.	Glycine	4-11	fibrillin 1	Homo sapiens	72-76
7895020-0	1994	Glycine-induced CA1 excitotoxicity in the rat hippocampal slice.	Glycine	0-7	carbonic anhydrase 1	Rattus norvegicus	16-19
7895020-1	1994	We evaluated the effects of glycine exposure upon CA1-evoked response in the rat hippocampal slice.	Glycine	28-35	carbonic anhydrase 1	Rattus norvegicus	50-53
7895020-2	1994	Exposure to 10 mM glycine for 16 min produced rapid neuronal firing and increased orthodromic population spike (PS), followed by loss of CA1 neural transmission.	Glycine	18-25	carbonic anhydrase 1	Rattus norvegicus	137-140
7961880-4	1994	Similarly, mutation of glycine 43 (corresponding to glycine 12 in p21ras) to valine decreased forskolin-stimulated expression from the CRE-luciferase gene by a maximum of 50%, indicating that this mutation activates the G-protein and is potentially oncogenic.	Glycine	23-30	HRas proto-oncogene, GTPase	Homo sapiens	66-72
17002624-6	2006	RESULTS: DNA sequence analysis of the three LOCR+ D- individuals revealed a single heterozygous 286G>A nucleotide substitution resulting in a predicted Gly>Ser substitution at amino acid 96.	Glycine	152-155	OCRL inositol polyphosphate-5-phosphatase	Homo sapiens	44-48
7961880-4	1994	Similarly, mutation of glycine 43 (corresponding to glycine 12 in p21ras) to valine decreased forskolin-stimulated expression from the CRE-luciferase gene by a maximum of 50%, indicating that this mutation activates the G-protein and is potentially oncogenic.	Glycine	52-59	HRas proto-oncogene, GTPase	Homo sapiens	66-72
7533846-9	1994	We report here the identification, purification and partial characterization of a novel, heparin-binding horse serum glycoprotein that we have termed Glycine-Rich Adhesion Serum Protein--GRASP--to stress the fact that this protein has a high content of glycine and functions, in vitro, as an adhesion molecule for OLGs.	Glycine	150-157	trafficking regulator and scaffold protein tamalin	Homo sapiens	187-192
16982409-2	2006	GARS encodes glycyl-tRNA synthetase, the enzyme that couples glycine to its tRNA.	Glycine	61-68	glycyl-tRNA synthetase 1	Homo sapiens	0-4
7533846-9	1994	We report here the identification, purification and partial characterization of a novel, heparin-binding horse serum glycoprotein that we have termed Glycine-Rich Adhesion Serum Protein--GRASP--to stress the fact that this protein has a high content of glycine and functions, in vitro, as an adhesion molecule for OLGs.	Glycine	253-260	trafficking regulator and scaffold protein tamalin	Homo sapiens	187-192
7533846-13	1994	Second, the amino acid compositions differ significantly, e.g., GRASP is not histidine- but rather glycine-rich.	Glycine	99-106	trafficking regulator and scaffold protein tamalin	Homo sapiens	64-69
7774057-10	1995	Moreover, TA2 and B12 exhibited two common amino acids in their CDR3 regions, one glycine and one tyrosine, in positions 98 and 99, respectively.	Glycine	82-89	cerebellar degeneration-related 3	Mus musculus	64-68
16982409-2	2006	GARS encodes glycyl-tRNA synthetase, the enzyme that couples glycine to its tRNA.	Glycine	61-68	glycyl-tRNA synthetase 1	Homo sapiens	13-35
16606645-1	2006	The aim of this study was to determine whether the +896 A--&gt;G substitution of the Toll-like receptor 4 (TLR4) gene, causing the Asp299--&gt;Gly change in the extracellular domain of TLR4, influences treatment response in recent-onset rheumatoid arthritis.	Glycine	143-146	toll like receptor 4	Homo sapiens	85-105
7590907-1	1995	The octapeptide Gly-Lys-Val-Leu-Lys-Lys-Arg-Arg (termed leukocorticotropin, LCT) corresponding to the ACTH-like sequence 81-88 of human pro-interleukin-1 alpha and its derivative Tyr-Gly-Lys-Val-Leu-Lys-Lys-Arg-Arg were synthesized.	Glycine	16-19	interleukin 1 alpha	Homo sapiens	136-159
7739523-7	1995	In structure-function analyses, mutation of the site of Lck myristylation (glycine 2) partially restored phosphorylation at tyrosine 505 in BI-141 cells.	Glycine	75-82	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	56-59
16606645-1	2006	The aim of this study was to determine whether the +896 A--&gt;G substitution of the Toll-like receptor 4 (TLR4) gene, causing the Asp299--&gt;Gly change in the extracellular domain of TLR4, influences treatment response in recent-onset rheumatoid arthritis.	Glycine	143-146	toll like receptor 4	Homo sapiens	107-111
16606645-1	2006	The aim of this study was to determine whether the +896 A--&gt;G substitution of the Toll-like receptor 4 (TLR4) gene, causing the Asp299--&gt;Gly change in the extracellular domain of TLR4, influences treatment response in recent-onset rheumatoid arthritis.	Glycine	143-146	toll like receptor 4	Homo sapiens	185-189
7753621-8	1995	Bacterial extract containing the fusion protein catalyses the aminoacylation of bovine tRNA with [14C]-gly at 10-fold increased level above normal bacterial extract and confirms that the cDNA encodes human GlyRS.	Glycine	103-106	glycyl-tRNA synthetase 1	Homo sapiens	206-211
16843004-6	2006	We have confirmed that this strain lacks DAO activity and shown for the first time it has increased occupancy of the NMDAR glycine site due to elevated extracellular D-serine levels and has enhanced NMDAR function in vivo.	Glycine	123-130	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	117-122
7718575-8	1995	The GCD cleaved the fluorogenic peptides Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 and Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 with catalytic efficiency close to full length human gelatinase A.	Glycine	53-56	guanylate cyclase 2E, pseudogene	Homo sapiens	4-7
16778374-2	2006	We report a Japanese patient with NPC caused by a homozygous c.2974 G &gt; T mutation of the NPC1 gene, which predicts a glycine (GGG) to tryptophan (TGG) change at codon 992 (designated as p.G992W).	Glycine	121-128	NPC intracellular cholesterol transporter 1	Homo sapiens	34-37
7720475-6	1995	These observations suggest that the presence of Gly-86 in the HLA beta-chain and surrounding amino acid sequence of HLA-DRB1*1502 is strongly associated with susceptibility to UC.	Glycine	48-51	major histocompatibility complex, class I, B	Homo sapiens	62-70
16778374-2	2006	We report a Japanese patient with NPC caused by a homozygous c.2974 G &gt; T mutation of the NPC1 gene, which predicts a glycine (GGG) to tryptophan (TGG) change at codon 992 (designated as p.G992W).	Glycine	121-128	NPC intracellular cholesterol transporter 1	Homo sapiens	93-97
7706490-3	1995	One mutation (G289V) occurred in exon 15 and converted a glycine in a collagenous domain of COL4A5 to a valine.	Glycine	57-64	collagen type IV alpha 5 chain	Homo sapiens	92-98
16754718-1	2006	Tyrosine and glycine constitute 40% of complementarity determining region 3 of the immunoglobulin heavy chain (CDR-H3), the center of the classic antigen-binding site.	Glycine	13-20	immunoglobulin heavy variable 2-3	Mus musculus	83-109
7891694-7	1995	The ERCC1-binding domain on XPA was previously mapped to a region containing two highly conserved XPA sequences, Gly-72 to Phe-75 and Glu-78 to Glu-84, which are termed the G and E motifs, respectively.	Glycine	113-116	ERCC excision repair 1, endonuclease non-catalytic subunit	Homo sapiens	4-9
16796587-3	2006	Here, we describe a 44-year-old patient with clinical features of CADASIL who was a carrier of a new Notch3 mutation: cys128-->gly.	Glycine	127-130	notch receptor 3	Homo sapiens	101-107
16432806-2	2006	By internal acylation of Lys, Orn, L-1,4-diaminobutyric acid (Dab), L-1,3-diaminopropionic acid (Dap) at position 4 with the C-terminal Gly of the peptide tail, we prepared cyclo-(4-9)-[Lys(4), Gly(9)]-PA (pA(2) = 8.77 +/- 0.27), 1, and cyclo-(4-9)-[Orn(4), Gly(9)]-PA (pA(2) = 8.81 +/- 0.25), 3, which are equipotent with PA (pA(2) = 8.68 +/- 0.18) in the rat uterotonic assay and cyclo-(4-9)-[Dab(4), Gly(9)]-PA, 4, cyclo-(4-9)-[Dap(4), Gly(9)]-PA, 5, and cyclo-(4-9)-[Pmp(1), Lys(4), Gly(9)]-PA, 2, which were weaker OTAs.	Glycine	136-139	death-associated protein	Rattus norvegicus	97-100
7864860-2	1995	In the region preceeding the kinase domain of T beta R-I there is a glycine- and serine-rich sequence, termed the GS domain, which has been shown to be phosphorylated by T beta R-II.	Glycine	68-75	transforming growth factor beta receptor 1	Homo sapiens	46-56
16432806-2	2006	By internal acylation of Lys, Orn, L-1,4-diaminobutyric acid (Dab), L-1,3-diaminopropionic acid (Dap) at position 4 with the C-terminal Gly of the peptide tail, we prepared cyclo-(4-9)-[Lys(4), Gly(9)]-PA (pA(2) = 8.77 +/- 0.27), 1, and cyclo-(4-9)-[Orn(4), Gly(9)]-PA (pA(2) = 8.81 +/- 0.25), 3, which are equipotent with PA (pA(2) = 8.68 +/- 0.18) in the rat uterotonic assay and cyclo-(4-9)-[Dab(4), Gly(9)]-PA, 4, cyclo-(4-9)-[Dap(4), Gly(9)]-PA, 5, and cyclo-(4-9)-[Pmp(1), Lys(4), Gly(9)]-PA, 2, which were weaker OTAs.	Glycine	136-139	death-associated protein	Rattus norvegicus	431-434
7867625-3	1995	The deduced amino acid sequence shares approximately 60% similarity with the mammalian NPR-C but it lacks the Gly-rich prosequence present in the mammalian counterparts.	Glycine	110-113	natriuretic peptide receptor 3	Homo sapiens	87-92
16432806-2	2006	By internal acylation of Lys, Orn, L-1,4-diaminobutyric acid (Dab), L-1,3-diaminopropionic acid (Dap) at position 4 with the C-terminal Gly of the peptide tail, we prepared cyclo-(4-9)-[Lys(4), Gly(9)]-PA (pA(2) = 8.77 +/- 0.27), 1, and cyclo-(4-9)-[Orn(4), Gly(9)]-PA (pA(2) = 8.81 +/- 0.25), 3, which are equipotent with PA (pA(2) = 8.68 +/- 0.18) in the rat uterotonic assay and cyclo-(4-9)-[Dab(4), Gly(9)]-PA, 4, cyclo-(4-9)-[Dap(4), Gly(9)]-PA, 5, and cyclo-(4-9)-[Pmp(1), Lys(4), Gly(9)]-PA, 2, which were weaker OTAs.	Glycine	194-197	death-associated protein	Rattus norvegicus	97-100
16432806-2	2006	By internal acylation of Lys, Orn, L-1,4-diaminobutyric acid (Dab), L-1,3-diaminopropionic acid (Dap) at position 4 with the C-terminal Gly of the peptide tail, we prepared cyclo-(4-9)-[Lys(4), Gly(9)]-PA (pA(2) = 8.77 +/- 0.27), 1, and cyclo-(4-9)-[Orn(4), Gly(9)]-PA (pA(2) = 8.81 +/- 0.25), 3, which are equipotent with PA (pA(2) = 8.68 +/- 0.18) in the rat uterotonic assay and cyclo-(4-9)-[Dab(4), Gly(9)]-PA, 4, cyclo-(4-9)-[Dap(4), Gly(9)]-PA, 5, and cyclo-(4-9)-[Pmp(1), Lys(4), Gly(9)]-PA, 2, which were weaker OTAs.	Glycine	194-197	death-associated protein	Rattus norvegicus	97-100
16716838-1	2006	The effects of cadmium (Cd(2+)) on glycine-induced Cl(-) current (I(Gly)) were investigated in acutely dissociated rat hippocampal CA1 neurons using the conventional whole-cell patch-clamp technique in this study.	Glycine	35-42	carbonic anhydrase 1	Rattus norvegicus	131-134
7896186-1	1995	Tumorigenic roles were variably suggested for HER-2 and INT-2 oncogene amplifications and the "atypical" aspartate to glycine mutability in the butyrylcholinesterase (BCHE) gene in ovarian adenocarcinomas.	Glycine	118-125	butyrylcholinesterase	Homo sapiens	144-165
7896186-1	1995	Tumorigenic roles were variably suggested for HER-2 and INT-2 oncogene amplifications and the "atypical" aspartate to glycine mutability in the butyrylcholinesterase (BCHE) gene in ovarian adenocarcinomas.	Glycine	118-125	butyrylcholinesterase	Homo sapiens	167-171
16616186-3	2006	For proper function, these ion channels have to be anchored to the cytoskeleton, and in the case of the inhibitory glycine and gamma-amino-butyric acid type A (GABA(A)) receptors this interaction is mediated by a gephyrin centered scaffold.	Glycine	115-122	gephyrin	Homo sapiens	213-221
7802655-3	1994	In particular, the long run of consecutive glycines and histidines of delta and YY1 is missing.	Glycine	43-51	YY1 transcription factor L homeolog	Xenopus laevis	80-83
16574906-8	2006	This occurred via an Arg-Gly-Asp (RGD) peptide-independent pathway through activation of G(i/o) proteins, phosphatidylinositol 3-kinase, Akt, and eNOS.	Glycine	25-28	nitric oxide synthase 3, endothelial cell	Mus musculus	146-150
7823028-13	1994	The results indicate that GLYT2 is involved in the termination of glycine neurotransmission at the classical inhibitory system in the hindbrain.	Glycine	66-73	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	26-31
7945384-2	1994	Sequence analysis showed that PLC-alpha is highly conserved among rat, mouse, and calf and that it has two Trp-Cys-Gly-His-Cys-Lys motifs completely conserved in the mammals.	Glycine	115-118	protein disulfide isomerase associated 3	Mus musculus	30-39
7945384-5	1994	PLC-alpha is supposed to be a member not of PLC superfamily but of Trp-Cys-Gly-His-Cys-Lys motif-containing proteins consisting of protein disulfide isomerase, P5, ERp72, and thioredoxin.	Glycine	75-78	protein disulfide isomerase associated 3	Mus musculus	0-9
16472927-9	2006	In addition, we have observed AMPA-induced depression of evoked release of GABA and glycine onto lamina I NK1R+ neurons.	Glycine	84-91	tachykinin receptor 1	Rattus norvegicus	106-110
7829102-6	1994	Moreover, sequence analysis of the corresponding region of the Nramp gene from distantly related species indicated strong amino acid sequence conservation of TM2, including an invariant glycine at position 105.	Glycine	186-193	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	Mus musculus	63-68
16533811-2	2006	In this study, we address the function of the conserved glycine- and phenylalanine-rich (G/F-rich) region of the Escherichia coli DnaJ in the DnaK chaperone cycle.	Glycine	56-63	DnaJ	Escherichia coli	130-134
7910822-4	1994	The effects of pH and D2O on the kinetics of the oxidative half-reaction of D-amino-acid oxidase have been determined with glycine, D-alanine, and D-serine as substrates.	Glycine	123-130	D-amino acid oxidase	Homo sapiens	76-96
16604067-2	2006	The abnormal behavior of unc-17(e245) mutants, which have a glycine-to-arginine substitution in a transmembrane domain, is markedly improved by a mutant synaptobrevin with an isoleucine-to-aspartate substitution in its transmembrane domain.	Glycine	60-67	Vesicular acetylcholine transporter unc-17	Caenorhabditis elegans	25-31
8175783-5	1994	In the second group (Group 2), replacement with Gly, Pro, Ser, or Asp resulted in nonfunctional EF-2, but it did not affect the growth of cells co-expressing wild-type EF-2.	Glycine	48-51	elongation factor 2	Saccharomyces cerevisiae S288C	96-100
16455232-4	2006	Sequence analysis of the complete cDNA of the candidate gene, hairless (Hr), identified a homozygous G-to-T transition at nucleotide 3572, leading to the substitution of glycine by tryptophan, designated Gly960Trp.	Glycine	170-177	lysine demethylase and nuclear receptor corepressor	Mus musculus	62-70
8175672-1	1994	The metalloendopeptidase EC 3.4.24.15 is believed to degrade gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) by cleavage at the Tyr5-Gly6 bond.	Glycine	121-124	gonadotropin releasing hormone 1	Rattus norvegicus	61-91
8175672-1	1994	The metalloendopeptidase EC 3.4.24.15 is believed to degrade gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) by cleavage at the Tyr5-Gly6 bond.	Glycine	121-124	gonadotropin releasing hormone 1	Rattus norvegicus	93-97
8175672-1	1994	The metalloendopeptidase EC 3.4.24.15 is believed to degrade gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) by cleavage at the Tyr5-Gly6 bond.	Glycine	137-140	gonadotropin releasing hormone 1	Rattus norvegicus	61-91
8175672-1	1994	The metalloendopeptidase EC 3.4.24.15 is believed to degrade gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) by cleavage at the Tyr5-Gly6 bond.	Glycine	137-140	gonadotropin releasing hormone 1	Rattus norvegicus	93-97
7734248-1	1994	Glycine methyltransferase from rat liver is a tetrameric enzyme with 292 amino acid residues in each identical subunit and catalyzes the AdoMet-dependent methylation of glycine to form sarcosine.	Glycine	169-176	glycine N-methyltransferase	Rattus norvegicus	0-25
16455232-4	2006	Sequence analysis of the complete cDNA of the candidate gene, hairless (Hr), identified a homozygous G-to-T transition at nucleotide 3572, leading to the substitution of glycine by tryptophan, designated Gly960Trp.	Glycine	170-177	lysine demethylase and nuclear receptor corepressor	Mus musculus	72-74
16557226-11	2006	There was striking regenerative response 48 h after Gly-ARF characterized by enhanced BrdU incorporation and reduced expression of p27(Kip).	Glycine	52-55	cyclin-dependent kinase inhibitor 1B	Rattus norvegicus	131-134
16005884-2	2006	The G-allele carriers of the SREBF-1 gene C-G polymorphism in exon 18c and coding for glycine at the protein level (G952G) have shown to associate more frequently with obesity and type 2 diabetes than the C-allele carriers.	Glycine	86-93	sterol regulatory element binding transcription factor 1	Homo sapiens	29-36
7938016-1	1994	Geranylgeranylated Rab proteins usually terminate in either Cys-Cys or Cys-Xaa-Cys, where Xaa is Ala, Ser, or Gly.	Glycine	110-113	RAB1A, member RAS oncogene family	Bos taurus	19-22
7908225-3	1994	Conditions have previously been established under which large, limiting, primary deuterium kinetic isotope effects can be measured with D-alanine, D-serine, and glycine as substrates for D-amino acid oxidase [Denu, J. M., &amp; Fitzpatrick, P. F. (1992) Biochemistry 31, 8207-8215].	Glycine	161-168	D-amino acid oxidase	Homo sapiens	187-207
16500365-1	2006	Genotyping analysis was performed for Gly146Ala polymorphism in the gene for steroidogenic factor-1 (SF-1), which is known to reduce the transactivation function by approximately 20%, in 72 cryptorchid patients and 136 control males, revealing that the Ala allele, the Ala/Gly genotype, and the Ala/Ala plus Ala/Gly genotype frequencies were significantly higher in the patients than in the control males.	Glycine	38-41	nuclear receptor subfamily 5 group A member 1	Homo sapiens	77-99
7512180-4	1994	Murine c-kit mutants encoding Gly-559 and/or Val-814, corresponding to human Gly-560 and/or Val-816, were constructed by site-directed mutagenesis and expressed in cells of a human embryonic kidney cell line (293T).	Glycine	30-33	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	7-12
7512180-4	1994	Murine c-kit mutants encoding Gly-559 and/or Val-814, corresponding to human Gly-560 and/or Val-816, were constructed by site-directed mutagenesis and expressed in cells of a human embryonic kidney cell line (293T).	Glycine	77-80	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	7-12
7929584-6	1994	Treatment of couplets with glycine derivatives of lithocholate and ursodeoxycholate, but not cholate or chenodeoxycholate, led to a marked relocalization of annexin II, which initially became concentrated at the basolateral membrane, then moved to a perinuclear distribution and finally to the apical membrane as the incubation progressed.	Glycine	27-34	annexin A2	Homo sapiens	157-167
7937106-9	1994	Furthermore, as this isoleucine residue is rather well-conserved within the ETS gene family, we show that mutation of the corresponding isoleucine of c-ets-2 into glycine also abrogates its DNA-binding and hence, transactivating properties.	Glycine	163-170	ETS proto-oncogene 2, transcription factor	Homo sapiens	152-157
16500365-1	2006	Genotyping analysis was performed for Gly146Ala polymorphism in the gene for steroidogenic factor-1 (SF-1), which is known to reduce the transactivation function by approximately 20%, in 72 cryptorchid patients and 136 control males, revealing that the Ala allele, the Ala/Gly genotype, and the Ala/Ala plus Ala/Gly genotype frequencies were significantly higher in the patients than in the control males.	Glycine	38-41	nuclear receptor subfamily 5 group A member 1	Homo sapiens	101-105
7528680-6	1994	The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C &gt;&gt; NR1 = NR1-NR2B = NR1-NR2D &gt; NR1-NR2A.	Glycine	4-11	glutamate ionotropic receptor NMDA type subunit 2D	Homo sapiens	223-227
16500365-1	2006	Genotyping analysis was performed for Gly146Ala polymorphism in the gene for steroidogenic factor-1 (SF-1), which is known to reduce the transactivation function by approximately 20%, in 72 cryptorchid patients and 136 control males, revealing that the Ala allele, the Ala/Gly genotype, and the Ala/Ala plus Ala/Gly genotype frequencies were significantly higher in the patients than in the control males.	Glycine	273-276	nuclear receptor subfamily 5 group A member 1	Homo sapiens	77-99
16500365-1	2006	Genotyping analysis was performed for Gly146Ala polymorphism in the gene for steroidogenic factor-1 (SF-1), which is known to reduce the transactivation function by approximately 20%, in 72 cryptorchid patients and 136 control males, revealing that the Ala allele, the Ala/Gly genotype, and the Ala/Ala plus Ala/Gly genotype frequencies were significantly higher in the patients than in the control males.	Glycine	273-276	nuclear receptor subfamily 5 group A member 1	Homo sapiens	101-105
7972490-2	1994	The cDNA library was made from poly(A)+ RNA from leaves challenged with mercuric chloride for 2 d. The two clones, pCh2 and pCh11, appear to encode class I chitinase isoforms with cysteine-rich domains (not found in pCh11 due to the incomplete sequence) and proline-/glycine-rich or proline-rich hinge domains, respectively.	Glycine	267-274	chitinase chem 5	Zea mays	156-165
16376148-3	2006	One approach to enhance NMDA receptor function is to increase the availability of the necessary co-agonist glycine at this modulatory site through inhibition of glycine reuptake from the synapse via glycine transporter-1 (GlyT1).	Glycine	107-114	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	199-220
8023165-1	1994	Peptide alpha amidation is required to produce some hormones, such as gastrin, from their glycine-extended precursors.	Glycine	90-97	gastrin	Homo sapiens	70-77
8023165-3	1994	However, both amidated gastrin and glycine-extended gastrin stimulate proliferation of exocrine pancreatic cell line AR4-2J through selective receptors for the substrate and the product, respectively, of peptide alpha amidation.	Glycine	35-42	gastrin	Homo sapiens	52-59
16376148-3	2006	One approach to enhance NMDA receptor function is to increase the availability of the necessary co-agonist glycine at this modulatory site through inhibition of glycine reuptake from the synapse via glycine transporter-1 (GlyT1).	Glycine	107-114	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	222-227
16376148-3	2006	One approach to enhance NMDA receptor function is to increase the availability of the necessary co-agonist glycine at this modulatory site through inhibition of glycine reuptake from the synapse via glycine transporter-1 (GlyT1).	Glycine	161-168	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	199-220
16376148-3	2006	One approach to enhance NMDA receptor function is to increase the availability of the necessary co-agonist glycine at this modulatory site through inhibition of glycine reuptake from the synapse via glycine transporter-1 (GlyT1).	Glycine	161-168	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	222-227
8033906-2	1994	Synthetic peptides related to amino acid residues 29-42 of human serum amyloid A (SAA), Tyr-Ile-Gly-Ser-Asp-Lys-Tyr-Phe-His-Ala-Arg-Gly-Asn-Tyr, were found to inhibit the adhesion of human T-lymphocytes and of mouse M4 melanoma cells to surfaces coated with the major cell adhesive glycoproteins of the extracellular matrix, laminin or fibronectin.	Glycine	132-135	fibronectin 1	Mus musculus	336-347
8206990-10	1994	Changing the P2 residue Phe353--&gt;Gly generated a mutant with a reactive site like antithrombin which was better at inhibiting thrombin or urokinase, but was much less active with APC or trypsin.	Glycine	36-39	serpin family C member 1	Homo sapiens	85-97
16376148-6	2006	In addition, recent electrophysiological findings and data from transgenic mouse models suggest that GlyT1 might also play a role in terminating the actions of glycine at strychnine-sensitive glycine receptors, and therefore GlyT1 antagonists also have potential for the treatment of conditions where activation of inhibitory pathways in the central nervous system might be beneficial.	Glycine	160-167	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	101-106
16607040-3	2006	The putative cytoplasmic N-terminus of mRECS1 has a high content of proline (23%) and glycine (12%) residues, contains one PPXY motif, multiple PXXP motifs and one overlapping P(T/S)AP and PPXY motif (P(T/S)APPXY).	Glycine	86-93	transmembrane BAX inhibitor motif containing 1	Mus musculus	39-45
7983681-2	1994	The aralkyl transferase (ArAlk) had glycine conjugating activity toward the following compounds: benzoyl-CoA &gt; butyryl-CoA, salicylyl-CoA &gt; heptanoyl-CoA, indoleacetyl-CoA.	Glycine	36-43	glycine N-phenylacetyltransferase	Bos taurus	25-30
16303211-3	2006	Aromatic amino acid substitution at the N-terminus in conjuction with the expansion of the 23-membered cyclic lactam MT-II scaffold to a 26-membered scaffold by addition of a Gly residue in position 10 leads to melanotropin peptides with enhanced receptor selectivity.	Glycine	175-178	metallothionein 2A	Homo sapiens	117-122
8183370-7	1994	Substitution of Gly 145 in BH1 domain or Trp 188 in BH2 domain completely abrogated Bcl-2"s death-repressor activity in interleukin-3 deprivation, gamma-irradiation and glucocorticoid-induced apoptosis.	Glycine	16-19	interleukin 3	Homo sapiens	120-133
8190097-7	1994	Glycine-dependent stimulation was seen at NR1A/NR2A and NR1A/NR2B receptors and may therefore involve a second polyamine binding site distinct from that which produces glycine-independent stimulation.	Glycine	0-7	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	61-65
16414450-6	2006	The present study examined the effects of oxLDL and gly-LDL on the transcription, expression, secretion, and subcellular distribution of PAI-1 in cultured human ECs.	Glycine	52-55	serpin family E member 1	Homo sapiens	137-142
8163480-4	1994	The primary sequence of CL-43 shows that it contains an N-terminal region of 28 residues, followed by a collagenous domain of 38 repeats of Gly-Xaa-Yaa and then a C-terminal section of 159 residues, containing a short "neck" region and the carbohydrate recognition domain with the conserved residues found in all C-type lectins.	Glycine	140-143	collectin-43	Bos taurus	24-29
8005744-1	1994	We report the synthesis of a cyclic analogue of epidermal growth factor sequence 33-42 with substitution of 1-aminocyclopropane-1-carboxylic acid for glycine at position 39 (N-acetyl-Cys-Val-Ile-Gly-Tyr-Ser-ACPCA-Asp-Arg-Cys-NH2).	Glycine	150-157	epidermal growth factor	Homo sapiens	48-71
16319129-4	2006	We show here that Fmrp is post-translationally methylated, primarily on its arginine-glycine-glycine box.	Glycine	85-92	Fmr1	Drosophila melanogaster	18-22
7513083-1	1994	We have characterized the expression of two members of a class of Arabidopsis thaliana glycine-rich, putative RNA-binding proteins that we denote Ccr1 and Ccr2.	Glycine	87-94	cinnamoyl coa reductase 1	Arabidopsis thaliana	146-150
16319129-4	2006	We show here that Fmrp is post-translationally methylated, primarily on its arginine-glycine-glycine box.	Glycine	93-100	Fmr1	Drosophila melanogaster	18-22
8106372-3	1994	Nonexchangeable proton and exchangeable amide (NH) proton resonances were assigned for the hen ovomucoid glycopeptide 1, Ser-Ile-Glu-Phe-Gly-Thr-Asn Ile-Ser-Lys, with pentasaccharide Man alpha 1-3 (Man alpha 1-6)Man beta 1-4GlcNAc beta 1-4GlcNAc beta 1-NH attached to the Asn7 gamma-carboxamide.	Glycine	137-140	adrenoceptor alpha 1D	Homo sapiens	187-196
8106372-3	1994	Nonexchangeable proton and exchangeable amide (NH) proton resonances were assigned for the hen ovomucoid glycopeptide 1, Ser-Ile-Glu-Phe-Gly-Thr-Asn Ile-Ser-Lys, with pentasaccharide Man alpha 1-3 (Man alpha 1-6)Man beta 1-4GlcNAc beta 1-4GlcNAc beta 1-NH attached to the Asn7 gamma-carboxamide.	Glycine	137-140	adrenoceptor alpha 1D	Homo sapiens	202-211
16052352-5	2006	However, two transporters, the proton amino acid transporter PAT1 (SLC36A1) and the IMINO transporter (SLC6A20) appear to play key roles in the resorption of glycine and proline.	Glycine	158-165	solute carrier family 36 member 1	Homo sapiens	61-65
8159808-0	1994	Glycine-extended post-translational processing intermediates of gastrin and cholecystokinin in the gut.	Glycine	0-7	gastrin	Homo sapiens	64-71
8159808-3	1994	In the present studies we used region specific antisera to characterize the carboxyl-terminally amidated and glycine-extended forms of gastrin and CCK in mammalian intestine.	Glycine	109-116	gastrin	Homo sapiens	135-142
16052352-5	2006	However, two transporters, the proton amino acid transporter PAT1 (SLC36A1) and the IMINO transporter (SLC6A20) appear to play key roles in the resorption of glycine and proline.	Glycine	158-165	solute carrier family 36 member 1	Homo sapiens	67-74
8159808-4	1994	Multiple amidated molecular forms of gastrin and CCK and their corresponding glycine-extended forms were detected throughout the most of the small bowel.	Glycine	77-84	gastrin	Homo sapiens	37-44
16052352-5	2006	However, two transporters, the proton amino acid transporter PAT1 (SLC36A1) and the IMINO transporter (SLC6A20) appear to play key roles in the resorption of glycine and proline.	Glycine	158-165	solute carrier family 6 member 20	Homo sapiens	103-110
16186124-6	2005	Of the 15 PAHX residues observed to be mutated in RD patients, 11 cluster in two distinct groups around the Fe(II) (Pro(173), His(175), Gln(176), Asp(177), and His(220)) and 2OG binding sites (Trp(193), Glu(197), Ile(199), Gly(204), Asn(269), and Arg(275)).	Glycine	223-226	phytanoyl-CoA 2-hydroxylase	Homo sapiens	10-14
7905794-0	1994	Inhibition of CD4+ T lymphocyte binding to fibronectin and immune-cell accumulation in inflammatory sites by non-peptidic mimetics of Arg-Gly-Asp.	Glycine	138-141	fibronectin 1	Mus musculus	43-54
16236030-0	2005	Contribution of conserved glycine residues to ATP action at human P2X1 receptors: mutagenesis indicates that the glycine at position 250 is important for channel function.	Glycine	26-33	purinergic receptor P2X, ligand gated ion channel, 1 L homeolog	Xenopus laevis	66-70
7508961-8	1994	The unusually large size difference of 5 kDa between MK2e and HK2e is due mainly to a different duplication rate of the glycine-rich peptide motifs in the respective V subdomains of the orthologous keratins.	Glycine	120-127	hexokinase 2	Mus musculus	62-65
16236030-0	2005	Contribution of conserved glycine residues to ATP action at human P2X1 receptors: mutagenesis indicates that the glycine at position 250 is important for channel function.	Glycine	113-120	purinergic receptor P2X, ligand gated ion channel, 1 L homeolog	Xenopus laevis	66-70
8060496-1	1994	Oncogenic p21 protein, encoded by the ras-oncogene, that causes malignant transformation of normal cells and many human tumors, is almost identical in sequence to its normal protooncogene-encoded counterpart protein, except for the substitution of arbitrary amino acids for the normally occurring amino acids at critical positions such as Gly 12 and Gln 61.	Glycine	339-342	H3 histone pseudogene 16	Homo sapiens	10-13
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	117-120	proprotein convertase subtilisin/kexin type 1	Homo sapiens	21-50
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	117-120	proprotein convertase subtilisin/kexin type 1	Homo sapiens	52-55
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	117-120	proprotein convertase subtilisin/kexin type 2	Homo sapiens	60-63
8188235-0	1994	Structure and chromosomal localization of the aminomethyltransferase gene (AMT) The gene for human aminomethyltransferase (AMT), also known as the T-protein of the glycine cleavage system, was isolated from a human placental cosmid library and examined by restriction mapping, polymerase chain reaction analysis, and DNA sequencing.	Glycine	164-171	aminomethyltransferase	Homo sapiens	46-68
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	180-183	proprotein convertase subtilisin/kexin type 1	Homo sapiens	21-50
8188235-0	1994	Structure and chromosomal localization of the aminomethyltransferase gene (AMT) The gene for human aminomethyltransferase (AMT), also known as the T-protein of the glycine cleavage system, was isolated from a human placental cosmid library and examined by restriction mapping, polymerase chain reaction analysis, and DNA sequencing.	Glycine	164-171	aminomethyltransferase	Homo sapiens	75-78
8188235-0	1994	Structure and chromosomal localization of the aminomethyltransferase gene (AMT) The gene for human aminomethyltransferase (AMT), also known as the T-protein of the glycine cleavage system, was isolated from a human placental cosmid library and examined by restriction mapping, polymerase chain reaction analysis, and DNA sequencing.	Glycine	164-171	aminomethyltransferase	Homo sapiens	99-121
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	180-183	proprotein convertase subtilisin/kexin type 1	Homo sapiens	52-55
8188235-0	1994	Structure and chromosomal localization of the aminomethyltransferase gene (AMT) The gene for human aminomethyltransferase (AMT), also known as the T-protein of the glycine cleavage system, was isolated from a human placental cosmid library and examined by restriction mapping, polymerase chain reaction analysis, and DNA sequencing.	Glycine	164-171	aminomethyltransferase	Homo sapiens	123-126
15979761-1	2005	Purified recombinant prohormone convertase 1 and 2 (PC1 and PC2) cleave a peptide containing cholecystokinin (CCK) 8 Gly Arg Arg and the carboxyl-terminal peptide liberating CCK 8 Gly Arg Arg.	Glycine	180-183	proprotein convertase subtilisin/kexin type 2	Homo sapiens	60-63
16226721-6	2005	SBAT1 excluded aromatic or charged amino acids, beta-amino acids, glycine, and GABA.	Glycine	66-73	solute carrier family 6 member 15	Homo sapiens	0-5
7504710-8	1994	Mast cell adhesion in the presence of SCF appeared to occur through an integrin receptor as adhesion was calcium dependent and could be blocked by an RGD (Ang, Gly, Asp)-containing peptide.	Glycine	160-163	kit ligand	Mus musculus	38-41
15956994-4	2005	SSR504734, a selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38 nM, respectively), blocked reversibly the ex vivo uptake of glycine (mouse cortical homogenates: ID50: 5 mg/kg i.p.	Glycine	160-167	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	73-78
7903251-0	1993	Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	38-51
8195828-2	1993	Inhibition of the enzyme dihydrofolate reductase (DHFR) depletes the available tetrahydrofolate and blocks the formation of thymidylate, purines, the amino acids methionine and glycine, and several other cell constituents.	Glycine	177-184	dihydrofolate reductase	Homo sapiens	25-48
16142371-6	2005	We also observed a stimulatory effect on proliferation by gastrin and glycine-extended gastrin on 2 and 3 of the cell lines respectively and an inhibitory effect of PD 135 on all 4 cell lines.	Glycine	70-77	gastrin	Homo sapiens	87-94
8195828-2	1993	Inhibition of the enzyme dihydrofolate reductase (DHFR) depletes the available tetrahydrofolate and blocks the formation of thymidylate, purines, the amino acids methionine and glycine, and several other cell constituents.	Glycine	177-184	dihydrofolate reductase	Homo sapiens	50-54
7906183-1	1993	Currents elicited by activation of GABAA, glycine (GLY) and glutamate (GLU) receptors (R) in pyramidal neurons of CA1 region from thin slices of rat hippocampus were studied using the tight-seal whole-cell recording techniques.	Glycine	42-49	carbonic anhydrase 1	Rattus norvegicus	114-117
7906183-1	1993	Currents elicited by activation of GABAA, glycine (GLY) and glutamate (GLU) receptors (R) in pyramidal neurons of CA1 region from thin slices of rat hippocampus were studied using the tight-seal whole-cell recording techniques.	Glycine	51-54	carbonic anhydrase 1	Rattus norvegicus	114-117
8119138-9	1994	Incubation in glycine-free and high magnesium medium abolished the action of NMDA on GnRH release.	Glycine	14-21	gonadotropin releasing hormone 1	Mus musculus	85-89
16051612-4	2005	The unique N-terminal end harbors a myristoylation motif, and we have shown here that PRMT8 is indeed modified by the attachment of a myristate to the glycine residue after the initiator methionine.	Glycine	151-158	protein arginine methyltransferase 8	Homo sapiens	86-91
8293561-7	1994	In addition, the peptide GRGDSP blocked adhesion to osteopontin, suggesting that integrins mediate Arg-Gly-Asp-dependent adhesion.	Glycine	103-106	secreted phosphoprotein 1	Homo sapiens	52-63
8250906-2	1993	The helix-stabilizing tendency of N-terminal amino acid in NPY (12-36) was found to be as follows: Thr &gt; Ser &gt; Gly &gt; Gln &gt; Cys &gt; Asn &gt; Asp &gt; Val &gt; Phe &gt; Glu &gt; Lys &gt; Tyr &gt; Ala = Trp &gt; His &gt; Arg, suggesting the importance of end capping.	Glycine	117-120	neuropeptide Y	Homo sapiens	59-62
16051612-7	2005	A glutathione S-transferase fusion protein of PRMT8 has type I PRMT activity, catalyzing the formation of omega-NG-monomethylated and asymmetrically omega-NG,NG-dimethylated arginine residues on a recombinant glycine- and arginine-rich substrate.	Glycine	209-216	protein arginine methyltransferase 8	Homo sapiens	46-51
15982908-4	2005	MFG-E8 has two domains: an Arg-Gly-Asp sequence that binds integrins alphavbeta3 and alphavbeta5 (expressed by human DCs and macrophages) and a phosphatidyl-serine (PS) binding sequence through which it associates to PS-containing membranes (among which exosomes).	Glycine	31-34	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	0-6
8282700-5	1994	A plasmid encoding ORF32 totally complemented the inability of strain DTC274 to grow on glucose minimal medium as well as the transient glycine starvation phenomenon in DTK-12, and ORF32 was designated tgs.	Glycine	136-143	hypothetical protein	Escherichia coli	19-24
8263509-5	1994	Phospholipases A2 and C and p-chloromercuribenzosulfonic acid were invariably effective in significantly inhibiting [3H]DCKA binding with [3H]Gly binding being unaltered.	Glycine	142-145	phospholipase A2 group IB	Rattus norvegicus	0-23
7974840-4	1994	A great share of glycine (20%) is typical of p50 amino acid composition as well as for other proteins of mRNP-particles.	Glycine	17-24	Y-box-binding protein 1	Oryctolagus cuniculus	45-48
8280139-7	1993	These three mutations result in changes of glycine to arginine and of tyrosine to aspartic acid at amino acid positions 71 and 486 of the UGT1A protein, and of leucine to proline and of tyrosine to aspartic acid at amino acid positions 132 and 487 of the UGT1D protein, respectively.	Glycine	43-50	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	255-260
8144352-0	1993	Hb Howick [beta 37(C3)Trp--&gt;Gly]: a new high oxygen affinity variant of the alpha 1 beta 2 contact.	Glycine	31-34	adrenoceptor alpha 1D	Homo sapiens	79-86
8144352-7	1993	The beta 37 residue is an alpha 1 beta 2 contact site and the substitution of the tryptophan for a glycine would be expected to result in a destabilization of the deoxy-hemoglobin form because of the reduced number of hydrogen bonds, salt bridges and van der Waal contacts between the alpha 1 and beta 2 chains.	Glycine	99-106	adrenoceptor alpha 1D	Homo sapiens	26-33
8144352-7	1993	The beta 37 residue is an alpha 1 beta 2 contact site and the substitution of the tryptophan for a glycine would be expected to result in a destabilization of the deoxy-hemoglobin form because of the reduced number of hydrogen bonds, salt bridges and van der Waal contacts between the alpha 1 and beta 2 chains.	Glycine	99-106	adrenoceptor alpha 1D	Homo sapiens	285-303
8254036-1	1993	Osteopontin is a phosphorylated, sialic acid-rich, noncollagenous bone matrix protein containing the Arg-Gly-Asp-Ser amino acid sequence responsible for cell adhesion.	Glycine	105-108	secreted phosphoprotein 1	Homo sapiens	0-11
8276894-17	1993	Two mutant H2b proteins, with either a glycine or proline substitution at the position of insertion of the pentapeptide in H2a, have metabolic fates similar to that of H2a.	Glycine	39-46	H2B clustered histone 21	Homo sapiens	11-14
7902340-2	1993	Thirty-three tumors were found to harbor H-ras mutations where a glycine to valine (G--&gt;T) change in codon 12 was the most common point mutation recorded (26 tumors).	Glycine	65-72	HRas proto-oncogene, GTPase	Homo sapiens	41-46
7906471-3	1993	NPY affected the release of [3H]-glycine, [3H]-dopamine, [3H]-5-hydroxytryptamine, and [3H]-choline chloride-derived radioactivity in rabbit retina and of [3H]-GABA, [3H]-5-hydroxytryptamine and [3H]-choline chloride-derived radioactivity in chicken retina in an energy requiring, NA+K(+)-ATPase dependent and calcium dependent manner.	Glycine	33-40	neuropeptide Y	Oryctolagus cuniculus	0-3
7691613-0	1993	Overlapping epitopes encompassing a point mutation (12 Gly--&gt;Arg) in p21 ras can be recognized by HLA-DR, -DP and -DQ restricted T cells.	Glycine	55-58	H3 histone pseudogene 16	Homo sapiens	72-75
7691613-5	1993	By repeated in vitro stimulation of peripheral blood mononuclear cells, several T cells clones could be generated which recognized a p21 ras derived peptide carrying a position 12 Gly--&gt;Arg substitution.	Glycine	180-183	H3 histone pseudogene 16	Homo sapiens	133-136
8401225-6	1993	Mutants that contained the single residue substitutions Ile-6--&gt;Gly or Tyr-13--&gt;Gly were reduced in potency to 4-30% compared with wild-type rC5a.	Glycine	67-70	complement C5	Rattus norvegicus	147-151
8401225-6	1993	Mutants that contained the single residue substitutions Ile-6--&gt;Gly or Tyr-13--&gt;Gly were reduced in potency to 4-30% compared with wild-type rC5a.	Glycine	86-89	complement C5	Rattus norvegicus	147-151
8359682-3	1993	The deduced DnaJ amino acid sequence exhibits the modular structure of other members of the DnaJ protein class including a glycine-rich region and the repeating consensus sequence CXXCXGXGX.	Glycine	123-130	DnaJ	Escherichia coli	12-16
8359682-3	1993	The deduced DnaJ amino acid sequence exhibits the modular structure of other members of the DnaJ protein class including a glycine-rich region and the repeating consensus sequence CXXCXGXGX.	Glycine	123-130	DnaJ	Escherichia coli	92-96
8514788-10	1993	Furthermore, the cysteine-rich segment of linker chain L1 has the sequence Asp-Gly-Ser-Asp-Glu which is characteristic of LDL receptor repeats.	Glycine	79-82	low density lipoprotein receptor	Homo sapiens	122-134
8496598-4	1993	While the complete germ-line revertant of VH3H9 retained a low level of DNA binding, the substitution of R96, a product of N base addition in the third complementarity determining region (CDR3), with glycine (G) was sufficient to abolish measureable DNA specificity.	Glycine	200-207	cerebellar degeneration-related 3	Mus musculus	188-192
8506140-4	1993	For the EcoRII methyltransferase, it has been shown that substitution of this catalytic cysteine by glycine is cytotoxic to E.coli cells expressing the mutant methyltransferase (Wyszynski et al.	Glycine	100-107	EcoRII methyltransferase	Escherichia coli	8-32
8495193-11	1993	We measured the time course of activation and binding of glycine to C4A and C4B.	Glycine	57-64	complement C4A (Rodgers blood group)	Homo sapiens	68-71
8362410-6	1993	In view of the published data on HLA class I nucleotide sequences, the antibody may recognize an antigeneic determinant including two amino acid residues, Asp-166 and Gly-167, in the alpha 2 helix of the class I molecule that are specific for A1, A23 and A24 so far analyzed.	Glycine	167-170	immunoglobulin kappa variable 2-24	Homo sapiens	247-250
8383626-2	1993	We report here on a Tn5tac1 insertion in Escherichia coli that results in a conditional (IPTG-elicited) folA mutant phenotype: During aerobic growth, IPTG caused decreased synthesis of dihydrofolate reductase (DHFR; encoded by the folA gene) and hypersensitivity to trimethoprim (a DHFR inhibitor); during anaerobic growth, IPTG elicited auxotrophy that was satisfied by thymine or glycine or threonine.	Glycine	382-389	Dihydrofolate reductase	Escherichia coli	185-208
8486612-1	1993	In order to characterize the intracellular processing event of lysosomal cathepsin B, the proenzyme was purified from the rat liver microsomal contents using a Con A-Sepharose column, a Sepharose-Gly-Phe-GlySc column, and an anti-cathepsin B IgG column.	Glycine	196-199	cathepsin B	Rattus norvegicus	73-84
7680040-3	1993	The KAP6.1 gene encodes a basic protein of 82 amino acids (M(r) = 8,296) with a combined glycine and tyrosine content of approximately 60 mol%.	Glycine	89-96	keratin-associated protein 6-1	Ovis aries	4-10
8423162-4	1993	folA-null strains were slow growing, formed small colonies, and were auxotrophic for thymidine, adenine, methionine, glycine, and pantothenate.	Glycine	117-124	dihydrofolate reductase type I	Escherichia coli	0-4
8464162-6	1993	In addition, another two types of a point mutation reducing ChE activity were reported on K variant (Ala-539--&gt;Thr) and a case of (Gly-365--&gt;Arg) in a patient with liver cirrhosis.	Glycine	134-137	butyrylcholinesterase	Homo sapiens	60-63
1478265-2	1992	In the Schaffer collateral-CA1 pyramidal cell synapses and in the perforant path-dentate granule cell synapses, glycine (5 x 10(-4) M) significantly enhanced the short-term potentiation (STP) induced by subthreshold tetanic stimulation, without affecting baseline responses.	Glycine	112-119	carbonic anhydrase 1	Rattus norvegicus	27-30
1478265-5	1992	These results suggest that exogenous glycine can facilitate the generation of LTP in the CA1 region and in the dentate gyrus but not in the CA3 region.	Glycine	37-44	carbonic anhydrase 1	Rattus norvegicus	89-92
1478265-8	1992	Together, these results make it probable that exogenously applied glycine and related amino acids facilitate the generation of LTP in the CA1 and dentate region by activating the glycine modulatory sites associated with NMDA receptors.	Glycine	66-73	carbonic anhydrase 1	Rattus norvegicus	138-141
1478265-8	1992	Together, these results make it probable that exogenously applied glycine and related amino acids facilitate the generation of LTP in the CA1 and dentate region by activating the glycine modulatory sites associated with NMDA receptors.	Glycine	179-186	carbonic anhydrase 1	Rattus norvegicus	138-141
1486236-3	1992	Certain metabolite sequences including Gly, Asp, Arg, and Ser (GAAS) proved to be critical for cell interactions, e.g. with fibronectin.	Glycine	39-42	fibronectin 1	Mus musculus	124-135
1526969-0	1992	Molecular cloning of a cDNA encoding chicken T-protein of the glycine cleavage system and expression of the functional protein in Escherichia coli.	Glycine	62-69	aminomethyltransferase	Gallus gallus	45-54
1526969-2	1992	DNA clones encoding chicken T-protein of the glycine cleavage system were isolated from chicken liver lambda gt10 cDNA libraries.	Glycine	45-52	aminomethyltransferase	Gallus gallus	28-37
1353889-3	1992	[3H]Glycine transport mediated by clone GLYT1 is blocked by sarcosine but is not blocked by methyl-aminoisobutyric acid or L-alanine, a substrate specificity similar to that described for a previously identified glycine-uptake system called system Gly.	Glycine	4-11	solute carrier family 6 member 9 L homeolog	Xenopus laevis	40-45
1353889-3	1992	[3H]Glycine transport mediated by clone GLYT1 is blocked by sarcosine but is not blocked by methyl-aminoisobutyric acid or L-alanine, a substrate specificity similar to that described for a previously identified glycine-uptake system called system Gly.	Glycine	212-219	solute carrier family 6 member 9 L homeolog	Xenopus laevis	40-45
1353889-3	1992	[3H]Glycine transport mediated by clone GLYT1 is blocked by sarcosine but is not blocked by methyl-aminoisobutyric acid or L-alanine, a substrate specificity similar to that described for a previously identified glycine-uptake system called system Gly.	Glycine	4-7	solute carrier family 6 member 9 L homeolog	Xenopus laevis	40-45
1353729-1	1992	Three peptides corresponding to glycine-rich internal sequences of the guinea pig liver transglutaminase molecule were synthesized.	Glycine	32-39	protein-glutamine gamma-glutamyltransferase 2	Cavia porcellus	88-104
1375326-2	1992	A mutation of the amino-terminal site of myristylation (glycine 2), which prevents stable association of p56lck with the plasma membrane, completely abolished the ability of F505 p56lck to enhance TCR-induced tyrosine protein phosphorylation.	Glycine	56-63	T cell receptor alpha variable 6-3	Mus musculus	197-200
1374164-8	1992	Furthermore, the heteromeric NMDA receptor channel can be activated by glycine alone.	Glycine	71-78	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	29-42
1374027-3	1992	Two mutants (Ser29 substituted by Arg-Leu-Pro-Gly, and Ser33 substituted by Cys-Gly-Asp) represent two naturally occurring variants of IGF II.	Glycine	46-49	insulin like growth factor 2	Homo sapiens	135-141
1374027-3	1992	Two mutants (Ser29 substituted by Arg-Leu-Pro-Gly, and Ser33 substituted by Cys-Gly-Asp) represent two naturally occurring variants of IGF II.	Glycine	80-83	insulin like growth factor 2	Homo sapiens	135-141
1565649-10	1992	Expression of the mutant with an additional glycine in the D1 domain in AtT-20 cells, a mouse pituitary cell line that can store vWf, led to the storage of the resulting dimers.	Glycine	44-51	Von Willebrand factor	Mus musculus	129-132
1572651-8	1992	All of the PSGs except PSG1, PSG4, and PSG8 contained the arginine-glycine-aspartic acid sequence at position 93-95 corresponding to the complementarity determining region 3 of immunoglobulin.	Glycine	67-74	pregnancy specific beta-1-glycoprotein 1	Homo sapiens	23-27
1572651-8	1992	All of the PSGs except PSG1, PSG4, and PSG8 contained the arginine-glycine-aspartic acid sequence at position 93-95 corresponding to the complementarity determining region 3 of immunoglobulin.	Glycine	67-74	pregnancy specific beta-1-glycoprotein 4	Homo sapiens	29-33
1602966-7	1992	The osmoprotective derivatives of phosphorylcholine which induce the synthesis of PLC in P. aeruginosa include choline, glycine betaine, and dimethylglycine, but not sarcosine (monomethylglycine) or glycine.	Glycine	120-127	heparan sulfate proteoglycan 2	Homo sapiens	82-85
1547506-5	1992	The C-terminal half of p110, which is linked to the p50 portion via a glycine-rich hinge, could also noncovalently bind to p50.	Glycine	70-77	spliceosome associated factor 3, U4/U6 recycling protein	Homo sapiens	23-27
1600374-1	1992	This paper describes a method for the direct gas/liquid chromatographic (GC) analysis of 46 glycine-conjugated bile acids, which differ from one another in the number, position and configuration of the hydroxyl groups at positions C-2, C-3, C-4, C-6, C-7 and/or C-12.	Glycine	92-99	complement C2	Homo sapiens	231-234
1600374-1	1992	This paper describes a method for the direct gas/liquid chromatographic (GC) analysis of 46 glycine-conjugated bile acids, which differ from one another in the number, position and configuration of the hydroxyl groups at positions C-2, C-3, C-4, C-6, C-7 and/or C-12.	Glycine	92-99	complement C4A (Rodgers blood group)	Homo sapiens	241-244
1718739-3	1991	The putative protein encoded by pax[zf-a] contains a paired box and a paired-type homeobox separated by a glycine-rich, acidic linker and a carboxy-terminal end which is remarkably rich in serine, threonine and proline residues.	Glycine	106-113	paired box 6a	Danio rerio	32-40
1822238-5	1991	These methods were used in a study of O-GlcNAc glycopeptides produced by purified O-GlcNAc transferase addition of GlcNAc to the synthetic peptides YSDSPSTST and YSGSPSTST in which Y is tyrosine, S is serine, D is aspartic acid, P is proline, T is threonine and G is glycine.	Glycine	267-274	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	38-46
1822238-5	1991	These methods were used in a study of O-GlcNAc glycopeptides produced by purified O-GlcNAc transferase addition of GlcNAc to the synthetic peptides YSDSPSTST and YSGSPSTST in which Y is tyrosine, S is serine, D is aspartic acid, P is proline, T is threonine and G is glycine.	Glycine	267-274	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	82-90
1812406-3	1991	Sixteen cerebelli processed progastrin via glycine-extended intermediates to bioactive, carboxyamidated gastrin-17 and -34, half of the gastrins being tyrosine O-sulfated.	Glycine	43-50	gastrin	Homo sapiens	31-38
1939196-6	1991	Compared to normal tau, the soluble PHF-tau contained 100% more glycine and 35% less lysine residue.	Glycine	64-71	microtubule associated protein tau	Homo sapiens	36-43
1783265-4	1991	TSH activity eluted as one major peak at pH 2.8 using a PBS-glycine buffer.	Glycine	60-67	thyrotropin subunit beta	Oreochromis niloticus	0-3
1931944-13	1991	265, 22547-22553], these results provide further evidence that Glu-185, located immediately adjacent to the glycine-rich loop, is located in the purine binding pocket of the active site of smooth muscle myosin.	Glycine	108-115	myosin heavy chain 14	Homo sapiens	203-209
1797352-11	1991	The functional role of glycine in the rat hippocampal CA1 region is discussed.	Glycine	23-30	carbonic anhydrase 1	Rattus norvegicus	54-57
1653604-2	1991	Oligodeoxyribonucleotide-directed random mutagenesis within the gene encoding the C102T protein variant of Saccharomyces cerevisiae iso-1-cytochrome c was used to generate a library of mutations at the evolutionary invariant residues Gly-6 and Phe-10 in the N-terminal helix.	Glycine	234-237	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	132-137
1714895-1	1991	The ubiquitin (Ub)-conjugating enzyme E2(25K) catalyzes the synthesis of multi-Ub chains in which successive Ub units are linked by an isopeptide bond involving the epsilon-amino group of Lys-48 of Ubn, and the COOH-terminal Gly residue of Ubn+1 (Chen, Z., and Pickart, C. M. (1990) J. Biol.	Glycine	225-228	ubiquitin conjugating enzyme E2 K	Bos taurus	38-44
1678422-21	1991	The reversal potential of -81 mV for the hyperpolarizing PSP was close to -82 mV for the Gly hyperpolarization.	Glycine	89-92	persephin	Rattus norvegicus	57-60
1894441-4	1991	Specifically, the pentapeptide sequence of [Trp3]-beta-CM-5, H-Tyr-Pro-Trp-Pro-Gly-OH (I) was modified at Pro-2 and Pro-4 by D-Pro substitutions to provide two diastereometric analogs, [Trp3-D-Pro-4]-beta-CM-5 (II) and [D-Pro2,4,Trp3]-beta-CM-5 (III).	Glycine	79-82	tRNA-Pro (anticodon TGG) 3-1	Homo sapiens	44-54
2002038-0	1991	Isolation and sequence determination of cDNA encoding T-protein of the glycine cleavage system.	Glycine	71-78	aminomethyltransferase	Gallus gallus	54-63
2002038-1	1991	T-protein is a component of the glycine cleavage system and catalyzes the tetrahydrofolate-dependent reaction.	Glycine	32-39	aminomethyltransferase	Gallus gallus	0-9
2001376-8	1991	Features of this sequence which showed the greatest similarity to mammalian osteopontin included a region in which seven of nine consecutive residues are aspartic acid, a recognition sequence for integrin-mediated cell binding (-Arg-Gly-Asp), and four possible recognition sequences for phosphorylation by casein kinase II.	Glycine	233-236	secreted phosphoprotein 1	Homo sapiens	76-87
1706597-9	1991	These glycine residues are located just before the point where the triple-helical portions of the C1q molecule appear to bend when viewed in the electron microscope.	Glycine	6-13	complement C1q A chain	Homo sapiens	98-101
1826081-10	1991	In addition, Fab fragments of anti-Tyr-Ile-Gly-Ser-Arg antibody inhibited platelet adhesion to laminin.	Glycine	43-46	FA complementation group B	Homo sapiens	13-16
1904500-0	1991	Length polymorphism in the threonine-glycine-encoding repeat region of the period gene in Drosophila.	Glycine	37-44	period	Drosophila melanogaster	75-81
1904500-1	1991	Single-fly polymerase chain reaction amplification and direct DNA sequencing revealed high levels of length polymorphism in the threonine-glycine encoding repeat region of the period (per) gene in natural populations of Drosophila melanogaster.	Glycine	138-145	period	Drosophila melanogaster	176-182
1899840-4	1991	PEP possesses multiple potential nucleic acid- and protein- binding regions: a glycine- and asparagine-rich amino terminus, four zinc finger motifs, two very acidic segments, two short basic stretches, and an alanine- and proline-rich carboxyl terminus.	Glycine	79-86	Protein on ecdysone puffs	Drosophila melanogaster	0-3
8219225-5	1993	Within this region, the mu-PAR domain 1 could be minimally humanized to bind human pro-u-PA by a substitution of as few as four of the six nonconserved residues, thereby identifying the residues arginine-2, lysine-7, threonine-8, and glycine-10 as important in determining binding specificity.	Glycine	234-241	plasminogen activator, urokinase	Mus musculus	25-29
8287052-0	1993	Synthetic Arg-Gly-Asp-Ser analogues of the cell recognition site of fibronectin that retain antimetastatic and anti-cell adhesive properties.	Glycine	14-17	fibronectin 1	Mus musculus	68-79
8287052-1	1993	Synthetic peptide analogues of the Arg-Gly-Asp-Ser (RGDS) sequence of fibronectin in which the amino acid of Gly was substituted with another one, named X, i.e. Arg-X-Asp-Ser (R-X-DS), and N-terminal modified R-X-DS have been synthesized to examine their antimetastatic effects in murine lung or liver metastasis models, as well as the inhibitory effect on tumor cell invasion, migration and adhesion in vitro.	Glycine	39-42	fibronectin 1	Mus musculus	70-81
8232202-0	1993	Activity of the yeast MAP kinase homologue Slt2 is critically required for cell integrity at 37 degrees C. Deletion of the SLT2 gene of Saccharomyces cerevisiae, which codes for a homologue of MAP (mitogen-activated) protein kinases, causes an autolytic lethal phenotype in cells grown at 37 degrees C. The gene encodes domains characteristic of protein kinases, which include a lysine (at position 54) that lies 19 residues from a glycine-rich cluster, considered to be the putative ATP binding site.	Glycine	432-439	mitogen-activated serine/threonine-protein kinase SLT2	Saccharomyces cerevisiae S288C	43-47
8399818-3	1993	The serine and glycine metabolizing enzyme serine hydroxymethyltransferase (SHMT) is suggested as the most likely candidate for this single major gene locus.	Glycine	15-22	serine hydroxymethyltransferase 1	Homo sapiens	43-74
8399818-3	1993	The serine and glycine metabolizing enzyme serine hydroxymethyltransferase (SHMT) is suggested as the most likely candidate for this single major gene locus.	Glycine	15-22	serine hydroxymethyltransferase 1	Homo sapiens	76-80
8338834-13	1993	In (G12D)p21ras, replacement of GDP by GTP gamma S causes the resonances of glycines 10, 13, 15, 60, and 75 and isoleucine 21 and four others to shift from their GDP-specific positions.	Glycine	76-84	HRas proto-oncogene, GTPase	Homo sapiens	9-15
8329399-3	1993	When GTP gamma S is substituted for GDP in cellular N-ras p21, the chemical shifts of resonances Asp-47, -126, -154, and Asn-172, as well as Gly-77 and -151, are not sensitive to nucleotide exchange, whereas Asp-30, -33, -38, -54, -57, -69, -92, -105, and -119 are affected.	Glycine	141-144	H3 histone pseudogene 16	Homo sapiens	58-61
8102327-4	1993	However substantial quantities of glycine extended gastrin and PAM are present in plasma.	Glycine	34-41	gastrin	Homo sapiens	51-58
8440932-4	1993	Molecular cloning of the bovine PrP gene showed that it encodes a protein of 256 or 264 amino acids with five or six Gly:Pro-rich octarepeats, respectively, in contrast to all other mammalian PrP genes, which encode only five octarepeats.	Glycine	117-120	PRP@	Bos taurus	32-35
8485574-4	1993	A base substitution was identified in the peripherin (RDS) gene and DNA sequencing revealed a G to A transition in codon 167 that substitutes aspartic acid for a highly conserved glycine.	Glycine	179-186	peripherin	Homo sapiens	42-52
7680040-2	1993	To study the role and regulation of one of these families, the glycine/tyrosine-rich keratin-associated proteins encoded by the KAP6 gene family, a partial wool follicle cDNA clone encoding a sheep KAP6 protein was sequenced and the corresponding gene isolated from a sheep cosmid library.	Glycine	63-70	keratin-associated protein 6-1	Ovis aries	128-132
7682659-1	1993	The actions of Pb2+ on NMDA channel currents of acutely dissociated hippocampal CA1- and CA3-neurones from adult rats activated by aspartate plus glycine (asp/gly) were examined.	Glycine	146-153	carbonic anhydrase 1	Rattus norvegicus	80-83
8380576-2	1993	In the present study, the single-site hEGF mutants Tyr13--&gt;His, Tyr22--&gt;Asp, Ile23--&gt;Thr, and Leu26--&gt;Gly were genetically combined with the Leu47--&gt;Ala hEGF mutant to produce a series of double-site mutant hEGF gene products having alterations simultaneously at two sites, in separate domains, within the same hEGF molecule.	Glycine	114-117	epidermal growth factor	Homo sapiens	38-42
8386347-1	1993	Brief perfusion of adult rat hippocampal slices with high concentrations of glycine results in a slowly developing, long-lasting increase in synaptic responses in field CA1.	Glycine	76-83	carbonic anhydrase 1	Rattus norvegicus	169-172
8385751-2	1993	TAG (100-200 microM) dose-dependently and reversibly antagonized the ability of glycine and taurine to activate chloride permeable ionic channels in these patches.	Glycine	80-87	long intergenic non-protein coding RNA 1194	Homo sapiens	0-3
8385751-3	1993	This effect of TAG was due to shortening of the mean open time of the glycine and taurine activated channels.	Glycine	70-77	long intergenic non-protein coding RNA 1194	Homo sapiens	15-18
8380125-6	1993	Treatment of ECM with glycine (pH 2.7), which removes plasminogen activator inhibitor from the matrix, results in an increase in the rate of ACCS ECM degradation by uPA.	Glycine	22-29	1-aminocyclopropane-1-carboxylate synthase homolog (inactive)	Homo sapiens	141-145
8280370-4	1993	In contrast, nontumorigenic (immunogenic) variants (T-25-Adh and Rev-1) exhibited a Gly--&gt;Ser substitution at residue 242 of p53.	Glycine	84-87	transformation related protein 53, pseudogene	Mus musculus	128-131
1283639-5	1992	They also show close quantitative resemblance to the channels of hippocampal CA1 and dentate gyrus cells and of cerebellar granule cells, except that the NR1-NR2A combination has a lower glycine sensitivity than the native channels.	Glycine	187-194	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	154-157
1512231-6	1992	Bovine rhodopsin in disc membranes was digested with thermolysin to generate the C-terminal fragment (241-327), which was subsequently cleaved with cyanogen bromide to generate the peptide Val-Thr-Thr-Leu-Cys-Cys-Gly-Lys-Asn-Pro (318-327).	Glycine	213-216	rhodopsin	Bos taurus	7-16
1380167-5	1992	The sequence was found to correspond to that of a tryptic peptide of the EGF receptor beginning with Gly-85, which is in domain I, a region N terminal to the first cysteine-rich region of the receptor.	Glycine	101-104	epidermal growth factor	Mus musculus	73-76
1321147-2	1992	Ubiquitin-conjugating enzyme E2(25K) utilizes isolated ubiquitin as the substrate for synthesis of such chains, in which successive ubiquitin units are linked by isopeptide bonds involving the side chain of Lys-48 of one ubiquitin and the COOH group of Gly-76 of the next.	Glycine	253-256	ubiquitin conjugating enzyme E2 K	Homo sapiens	0-35
1355102-2	1992	The mutation is due to a C-G transversion which creates a premature termination codon (Ser447-Ter) and results in a truncated LPL molecule lacking the C-terminal dipeptide SER-GLY.	Glycine	176-179	lipoprotein lipase	Homo sapiens	126-129
1569940-2	1992	Mutations of residues in loop L1 (Gly-12 and Gly-13), in loop L2 (Thr-35 and Asp-38), and in loop L4 (Gln-61 and Glu-63) influence the reaction in different ways, but all of these mutant p21 proteins still form complexes with GAP.	Glycine	34-37	H3 histone pseudogene 16	Homo sapiens	187-190
1569940-2	1992	Mutations of residues in loop L1 (Gly-12 and Gly-13), in loop L2 (Thr-35 and Asp-38), and in loop L4 (Gln-61 and Glu-63) influence the reaction in different ways, but all of these mutant p21 proteins still form complexes with GAP.	Glycine	45-48	H3 histone pseudogene 16	Homo sapiens	187-190
1534022-1	1992	In vitro mutagenesis and germline transformation were used to create a Drosophila mutant, delta Asn20, lacking the N-linked glycosylation site near the amino terminus of the major rhodopsin (Asn20-Gly-Ser changed to Ile-Gly-Ser).	Glycine	197-200	neither inactivation nor afterpotential E	Drosophila melanogaster	180-189
1451779-5	1992	The individual substitutions of Pro-5 and Lys-7 in the latter peptide with Gly and Ala (or Glu), respectively, prevent its phosphorylation by cdc2, whereas the substitution of Lys-3 with Ala is well tolerated and the substitution of the target Ser with Thr actually improves phosphorylation.	Glycine	75-78	cyclin dependent kinase 1	Homo sapiens	142-146
1532151-3	1992	Functional homomeric zeta 1 channels expressed in Xenopus oocytes by injection of the subunit-specific mRNA exhibit current responses characteristic for the NMDA receptor channel such as activation by glycine, Ca2+ permeability, blocking by Mg2+ and activation by polyamine.	Glycine	201-208	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	157-170
1532572-8	1992	Both alpha v beta 6 and alpha v beta 5 are eluted from their respective immobilized ligands by a hexa-peptide containing the sequence Arg-Gly-Asp (RGD).	Glycine	138-141	adaptor related protein complex 5 subunit beta 1	Homo sapiens	32-38
1547341-0	1992	Antithrombin-III-Stockholm: a codon 392 (Gly----Asp) mutation with normal heparin binding and impaired serine protease reactivity.	Glycine	41-44	serpin family C member 1	Homo sapiens	0-16
1319725-4	1992	The IAP component of pertussis toxin blocked the inhibitory action of InP-gly on cAMP accumulation by reconstituted thyroid follicles (RTF), suggesting the participation of Gi protein.	Glycine	74-77	CD47 molecule	Sus scrofa	4-7
1319725-5	1992	But the same treatment with IAP was without effect on iodine metabolism, suggesting that there is a second target for InP-gly, more distal than Gi protein, or coupled to another G protein which is insensitive to the toxin.	Glycine	122-125	CD47 molecule	Sus scrofa	28-31
1737757-8	1992	Our studies reveal that the individual mutation of several hydrophobic amino acid residues such as Leu813, Ile810, and Trp800 and the glycine residue Gly804 also resulted in a severe decrease in or complete loss of CaM binding and activation of smMLCK.	Glycine	134-141	myosin light chain kinase	Homo sapiens	245-251
1371013-0	1992	Extensive size polymorphism of the human keratin 10 chain resides in the C-terminal V2 subdomain due to variable numbers and sizes of glycine loops.	Glycine	134-141	keratin 10	Homo sapiens	41-51
1371013-5	1992	Our results show that (i) the keratin 10 system is far more polymorphic than previously realized, (ii) the polymorphism is restricted to insertions and deletions of the glycine-rich quasipeptide repeats that form the glycine-loop motif in the C-terminal domain, (iii) the polymorphism can be accounted for by simple allelic variations that segregate by normal Mendelian mechanisms, and (iv) the differently sized PCR products most likely represent different alleles of a single-copy gene per haploid genome.	Glycine	169-176	keratin 10	Homo sapiens	30-40
1371013-5	1992	Our results show that (i) the keratin 10 system is far more polymorphic than previously realized, (ii) the polymorphism is restricted to insertions and deletions of the glycine-rich quasipeptide repeats that form the glycine-loop motif in the C-terminal domain, (iii) the polymorphism can be accounted for by simple allelic variations that segregate by normal Mendelian mechanisms, and (iv) the differently sized PCR products most likely represent different alleles of a single-copy gene per haploid genome.	Glycine	217-224	keratin 10	Homo sapiens	30-40
1730059-1	1992	A single intragastric administration of glycine, L- and D-alanine, and L-and D-serine into rats resulted in a more than 20-fold stimulation of intestinal mucosal ornithine decarboxylase (ODC) within 4 h. The stimulation of ODC activity was accompanied by an increase in the amount of immunoreactive ODC protein.	Glycine	40-47	ornithine decarboxylase 1	Rattus norvegicus	162-185
1730059-1	1992	A single intragastric administration of glycine, L- and D-alanine, and L-and D-serine into rats resulted in a more than 20-fold stimulation of intestinal mucosal ornithine decarboxylase (ODC) within 4 h. The stimulation of ODC activity was accompanied by an increase in the amount of immunoreactive ODC protein.	Glycine	40-47	ornithine decarboxylase 1	Rattus norvegicus	187-190
1730059-1	1992	A single intragastric administration of glycine, L- and D-alanine, and L-and D-serine into rats resulted in a more than 20-fold stimulation of intestinal mucosal ornithine decarboxylase (ODC) within 4 h. The stimulation of ODC activity was accompanied by an increase in the amount of immunoreactive ODC protein.	Glycine	40-47	ornithine decarboxylase 1	Rattus norvegicus	223-226
1730059-1	1992	A single intragastric administration of glycine, L- and D-alanine, and L-and D-serine into rats resulted in a more than 20-fold stimulation of intestinal mucosal ornithine decarboxylase (ODC) within 4 h. The stimulation of ODC activity was accompanied by an increase in the amount of immunoreactive ODC protein.	Glycine	40-47	ornithine decarboxylase 1	Rattus norvegicus	223-226
1730059-4	1992	Since the turnover rates of L-serine-induced and D-serine-induced intestinal ODC protein were the same as the non-induced control, we concluded that the induction by glycine and L-amino acids was brought about by an increased efficiency of translation of the ODC message.	Glycine	166-173	ornithine decarboxylase 1	Rattus norvegicus	77-80
1730059-4	1992	Since the turnover rates of L-serine-induced and D-serine-induced intestinal ODC protein were the same as the non-induced control, we concluded that the induction by glycine and L-amino acids was brought about by an increased efficiency of translation of the ODC message.	Glycine	166-173	ornithine decarboxylase 1	Rattus norvegicus	259-262
12106405-6	1992	These data suggest that glycine site antagonists of the NMDA receptor may have therapeutic potential for ameliorating neuronal damage associated with gp120.	Glycine	24-31	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	150-155
1729435-1	1992	An important step in the posttranslational modification of many bioactive neuropeptides, the carboxy-terminal amidation of glycine-extended peptides, is catalyzed by peptidylglycine alpha-amidating monooxygenase (PAM; EC 1.14.17.3).	Glycine	123-130	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	166-211
1729435-1	1992	An important step in the posttranslational modification of many bioactive neuropeptides, the carboxy-terminal amidation of glycine-extended peptides, is catalyzed by peptidylglycine alpha-amidating monooxygenase (PAM; EC 1.14.17.3).	Glycine	123-130	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	213-216
1660812-6	1991	These results suggest that the constraints of forming a flexible loop within the third complementarity-determining region, is a factor in the preference for a particular reading frame in Ig H D. For the TcR beta D segments, glycine is specified in most reading frames, and no significant preference is observed.	Glycine	224-231	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	203-206
1719076-4	1991	We show here that the binding of mAb OT145 ot the beta-chain of TCR is lost when residue 72 of V beta 6.7a is mutated from gly to glu.	Glycine	123-126	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	64-67
1786536-5	1991	Apparent elevations of taurine, glycine and glutamine levels in CA1 accompanied changes in glutamate concentrations.	Glycine	32-39	carbonic anhydrase 1	Rattus norvegicus	64-67
1935950-1	1991	The alpha-amidation of glycine-extended peptides is a two-step reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidylhydroxyglycine N-C lyase (PHL).	Glycine	23-30	peptidylglycine alpha-amidating monooxygenase L homeolog	Xenopus laevis	85-134
1935950-1	1991	The alpha-amidation of glycine-extended peptides is a two-step reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidylhydroxyglycine N-C lyase (PHL).	Glycine	23-30	peptidylglycine alpha-amidating monooxygenase L homeolog	Xenopus laevis	136-139
1833457-6	1991	Deviations from the optimal motif 234-Leu-Leu-Gly-Gly-237 may then explain the human IgG subclass specificity profile for human Fc gamma RI and Fc gamma RII.	Glycine	46-49	Fc gamma receptor Ia	Homo sapiens	128-139
1833457-6	1991	Deviations from the optimal motif 234-Leu-Leu-Gly-Gly-237 may then explain the human IgG subclass specificity profile for human Fc gamma RI and Fc gamma RII.	Glycine	50-53	Fc gamma receptor Ia	Homo sapiens	128-139
1961019-8	1991	Endoglin contains an arginine-glycine-aspartic acid sequence, a feature generally associated with extracellular matrix proteins which interact with integrins.	Glycine	30-37	endoglin	Homo sapiens	0-8
1896454-2	1991	VLA-4 binds to the peptide sequence Gly-Pro-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr (GPEILDVPST in single-letter code) on the alternatively spliced CS-1 form of FN, whereas VLA-5 binds to an Arg-Gly-Asp sequence found on all forms of FN.	Glycine	187-190	fibronectin 1	Mus musculus	153-155
1910037-9	1991	The Rsr1 protein shares with human Rap1 GTPases the four specific motifs, i.e. Gly-12, residues 32-40, Ala-59, and residues 64-70, that are required for GAP3-dependent activation of the Rap1 GTPases.	Glycine	79-82	RAP1A, member of RAS oncogene family	Homo sapiens	35-39
1714377-3	1991	In addition to the previously identified c-kit gene product (Kit+), a second normal Kit isoform (KitA+) containing an in-frame insertion, Gly-Asn-Asn-Lys, within the extracellular domain, was detected in murine mast cell cultures and mid-gestation placenta.	Glycine	138-141	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	84-87
1716439-7	1991	rMNK1 and mMNK1 differed from a recently reported MAP-2 kinase cDNA, termed ERK1, because of a nonconservative change in position 82, from Gly in ERK1 to Arg in rMNK1.	Glycine	139-142	microtubule-associated protein 2	Rattus norvegicus	50-55
1714460-4	1991	This region of SIS1 contains a glycine/methionine-rich region which, along with more amino-terminal sequences, is required for SIS1 to associate with a protein of apparent molecular mass of 40 kD.	Glycine	31-38	type II HSP40 co-chaperone SIS1	Saccharomyces cerevisiae S288C	15-19
1714460-4	1991	This region of SIS1 contains a glycine/methionine-rich region which, along with more amino-terminal sequences, is required for SIS1 to associate with a protein of apparent molecular mass of 40 kD.	Glycine	31-38	type II HSP40 co-chaperone SIS1	Saccharomyces cerevisiae S288C	127-131
1676542-3	1991	The HOX11 homeodomain is most similar to that of the murine gene Hlx and possesses a markedly glycine-rich variable region and an acidic carboxyl terminus.	Glycine	94-101	T cell leukemia, homeobox 1	Mus musculus	4-9
1676542-3	1991	The HOX11 homeodomain is most similar to that of the murine gene Hlx and possesses a markedly glycine-rich variable region and an acidic carboxyl terminus.	Glycine	94-101	H2.0-like homeobox	Mus musculus	65-68
1906475-5	1991	Based on the deduced amino acid sequence and immunochemical analysis of proteolytic fragments of NG2, the extracellular region can be divided into three domains: an amino terminal cysteine-containing domain which is stabilized by intrachain disulfide bonds, a serine-glycine-containing domain to which chondroitin sulfate chains are attached, and another cysteine-containing domain.	Glycine	267-274	chondroitin sulfate proteoglycan 4	Rattus norvegicus	97-100
1646125-5	1991	The recombinant 3C protease cleaved peptide bond Gln-Gly not only in virus polyprotein, but also in molecules of beta-galactosidase and bovine catalase.	Glycine	53-56	galactosidase beta 1	Bos taurus	113-131
1711211-5	1991	In contrast, the deletion of 44 additional residues led to a dramatic loss (86.3% +/- 7.8%; mean +/- SD) in the ability of this receptor to mediate EPO-induced growth, thus indicating that residues between Gly-352 and Met-396 constitute a functionally critical cytosolic subdomain.	Glycine	206-209	erythropoietin	Mus musculus	148-151
2033048-1	1991	To mimic the active sites (Trp-Cys-Gly-His-Cys) contained in two thioredoxin-like domains of the eukaryotic enzyme protein disulfide-isomerase (PDI, EC 5.3.4.1), the Pro-34 residue of Escherichia coli thioredoxin (Trx) was replaced by His using site-directed mutagenesis.	Glycine	35-38	protein-disulfide isomerase	Escherichia coli	115-142
2033048-1	1991	To mimic the active sites (Trp-Cys-Gly-His-Cys) contained in two thioredoxin-like domains of the eukaryotic enzyme protein disulfide-isomerase (PDI, EC 5.3.4.1), the Pro-34 residue of Escherichia coli thioredoxin (Trx) was replaced by His using site-directed mutagenesis.	Glycine	35-38	protein-disulfide isomerase	Escherichia coli	144-147
1850997-2	1991	Sequential analysis of the purified phosphopeptides demonstrated that the sites are -Thr-Arg-Thr-Tyr-Ser(PO4)38-Leu-Gly-Ser-Ala- and -Val-Arg-Leu-Leu-Gln-Asp-Ser(PO4)82-Val-Asp-, which are located within the amino-terminal head domain of vimentin.	Glycine	116-119	vimentin	Homo sapiens	238-246
1648712-2	1991	The rank order of potency in relaxing the precontracted fundus tissues was VIP greater than rat PHI greater than PHM greater than PHV greater than PHI-Gly greater than porcine PHI, rat PHI being only 2 times less potent than VIP.	Glycine	151-154	glucose-6-phosphate isomerase	Rattus norvegicus	147-150
1648712-2	1991	The rank order of potency in relaxing the precontracted fundus tissues was VIP greater than rat PHI greater than PHM greater than PHV greater than PHI-Gly greater than porcine PHI, rat PHI being only 2 times less potent than VIP.	Glycine	151-154	glucose-6-phosphate isomerase	Rattus norvegicus	147-150
1648712-2	1991	The rank order of potency in relaxing the precontracted fundus tissues was VIP greater than rat PHI greater than PHM greater than PHV greater than PHI-Gly greater than porcine PHI, rat PHI being only 2 times less potent than VIP.	Glycine	151-154	glucose-6-phosphate isomerase	Rattus norvegicus	147-150
1678195-2	1991	Although [Leu]- and [Met]enkephalin did not differ in Tyr or Tyr-Gly accumulation, the amount of Tyr-Gly-Gly resulting from [Met]enkephalin hydrolysis was greater than that resulting from [Leu]enkephalin hydrolysis, and [Met]enkephalin"s half-life in plasma was slightly shorter than that of [Leu]enkephalin.	Glycine	101-104	proenkephalin	Rattus norvegicus	129-139
1678195-2	1991	Although [Leu]- and [Met]enkephalin did not differ in Tyr or Tyr-Gly accumulation, the amount of Tyr-Gly-Gly resulting from [Met]enkephalin hydrolysis was greater than that resulting from [Leu]enkephalin hydrolysis, and [Met]enkephalin"s half-life in plasma was slightly shorter than that of [Leu]enkephalin.	Glycine	101-104	proenkephalin	Rattus norvegicus	129-139
1678195-2	1991	Although [Leu]- and [Met]enkephalin did not differ in Tyr or Tyr-Gly accumulation, the amount of Tyr-Gly-Gly resulting from [Met]enkephalin hydrolysis was greater than that resulting from [Leu]enkephalin hydrolysis, and [Met]enkephalin"s half-life in plasma was slightly shorter than that of [Leu]enkephalin.	Glycine	101-104	proenkephalin	Rattus norvegicus	129-139
1678195-2	1991	Although [Leu]- and [Met]enkephalin did not differ in Tyr or Tyr-Gly accumulation, the amount of Tyr-Gly-Gly resulting from [Met]enkephalin hydrolysis was greater than that resulting from [Leu]enkephalin hydrolysis, and [Met]enkephalin"s half-life in plasma was slightly shorter than that of [Leu]enkephalin.	Glycine	101-104	proenkephalin	Rattus norvegicus	129-139
1704355-4	1991	EGF was coupled to the activated dextran through the amino terminus and glycine was added to block residual activity.	Glycine	72-79	epidermal growth factor	Homo sapiens	0-3
1670775-16	1991	In order to investigate their possible use in vivo studies, the degradation of gamma-L-Glu-D-Aad and delta-L-Aad-L-Cys-Gly by gamma-GT was investigated.	Glycine	119-122	gamma-glutamyltransferase 1	Rattus norvegicus	126-134
1773057-2	1991	The gastrin mRNA of each animal encodes a preprogastrin of 104 amino acids consisting of a signal peptide, a prosegment of 37 amino acids, and a gastrin 34 sequence, followed by a glycine (the amide donor).	Glycine	180-187	gastrin	Homo sapiens	4-11
1773057-2	1991	The gastrin mRNA of each animal encodes a preprogastrin of 104 amino acids consisting of a signal peptide, a prosegment of 37 amino acids, and a gastrin 34 sequence, followed by a glycine (the amide donor).	Glycine	180-187	gastrin	Homo sapiens	42-55
1725860-6	1991	Absence of the two and four cysteines in the N-terminal region in the human and rat IGFBP-6 resulted in the deletion of the invariant Gly-Cys-Gly-Cys-Cys sequence which is present in all the other five IGFBPs.	Glycine	134-137	insulin like growth factor binding protein 1	Homo sapiens	202-208
1725860-6	1991	Absence of the two and four cysteines in the N-terminal region in the human and rat IGFBP-6 resulted in the deletion of the invariant Gly-Cys-Gly-Cys-Cys sequence which is present in all the other five IGFBPs.	Glycine	142-145	insulin like growth factor binding protein 1	Homo sapiens	202-208
1702390-5	1990	Close to the amino terminus there is a glycine-rich region which SRP68 has in common with some RNA-binding proteins.	Glycine	39-46	signal recognition particle 68	Canis lupus familiaris	65-70
16101730-10	2005	Quantitative RT-PCR revealed elevated myeloperoxidase mRNA after glycine versus GdCl3 and MP pretreatment (3.2- and 3.4-fold, P=0.011, respectively), without difference to controls (2.9-fold of glycine).	Glycine	65-72	myeloperoxidase	Rattus norvegicus	38-53
2271648-3	1990	PSG9 and PSG10 are representatives of two distinct classes of PSG protein that have N-termini with or without the Arg-Gly-Asp motif implicated in adhesion.	Glycine	118-121	pregnancy specific beta-1-glycoprotein 9	Homo sapiens	0-4
16101730-10	2005	Quantitative RT-PCR revealed elevated myeloperoxidase mRNA after glycine versus GdCl3 and MP pretreatment (3.2- and 3.4-fold, P=0.011, respectively), without difference to controls (2.9-fold of glycine).	Glycine	194-201	myeloperoxidase	Rattus norvegicus	38-53
16135748-2	2005	We investigated the gating reaction mechanism of fully liganded NR1/NR2A recombinant NMDARs (expressed in Xenopus oocytes) by fitting all possible three-closed/two-open-state, noncyclic kinetic schemes to currents elicited by saturating concentrations of glutamate plus glycine.	Glycine	270-277	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	64-67
1697929-6	1990	Furthermore, activation of p56lck by mutation of the carboxy-terminal tyrosine residue was rendered less efficient by substituting an alanine residue for the amino-terminal glycine.	Glycine	173-180	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	27-33
2168884-1	1990	Two gastrin analogs containing a D- and a L-tetrafluorinated tyrosyl residue (Arg-Arg-Leu-Glu-Glu-Glu-Glu-Glu-Ala-(F4)Tyr-Gly) were synthesized and tested as substrates and inhibitors of the insulin receptor kinase.	Glycine	122-125	gastrin	Homo sapiens	4-11
16007099-4	2005	We show that p16(INK4a) suppresses the activity of c-Jun N-terminal kinases (JNKs) and that it binds to the glycine-rich loop of the N-terminal domain of JNK3.	Glycine	108-115	mitogen-activated protein kinase 10	Homo sapiens	154-158
1689609-2	1990	We have made a mutein of human G-CSF, KW-2228, in which Thr-1, Leu-3, Gly-4, Pro-5, and Cys-17 were respectively substituted with Ala, Thr, Tyr, Arg, and Ser; showed more potent G-CSF activity; and retained full biological activity and receptor binding capacity at least 2 weeks of radioiodination.	Glycine	70-73	colony stimulating factor 3	Homo sapiens	31-36
16050745-5	2005	MP2/aug-cc-pVTZ predicts that the intramolecular seven-membered ring N-H...O=C hydrogen-bonding strength has a value of 5.54 kcal/mol in glycine dipeptide and 5.73 and 5.19 kcal/mol in alanine dipeptides, while the steric repulsive interactions of the seven-membered ring conformers are 4.13 kcal/mol in glycine dipeptide and 6.62 and 3.71 kcal/mol in alanine dipeptides.	Glycine	137-144	tryptase pseudogene 1	Homo sapiens	0-3
15994556-8	2005	An MHC I molecule containing a single cysteine residue in an artificial glycine and alanine intracytoplasmic domain was endocytosed and degraded in the presence of MIR1.	Glycine	72-79	fibronectin type III and SPRY domain containing 1	Homo sapiens	164-168
2318314-0	1990	Identification of the Arg-Gly-Asp sequence in laminin A chain as a latent cell-binding site being exposed in fragment P1.	Glycine	26-29	laminin subunit alpha 1	Homo sapiens	46-61
16032931-2	2005	We have previously shown that the aminoterminal hexapetide GNAEGR of lamin C2 following the start methionine is essential for its association with the nuclear envelope and that the aminoterminal glycine of the hexapeptide is myristoylated.	Glycine	195-202	lamin A/C	Rattus norvegicus	69-77
2295596-3	1990	Suppressors that increase the amount of beta-lactamase activity of the Gly-68 allele of beta-lactamase were isolated and some mapped to the gene encoding glycyl-tRNA synthetase (glyS).	Glycine	71-74	glycyl-tRNA synthetase 1	Homo sapiens	154-176
2295596-3	1990	Suppressors that increase the amount of beta-lactamase activity of the Gly-68 allele of beta-lactamase were isolated and some mapped to the gene encoding glycyl-tRNA synthetase (glyS).	Glycine	71-74	glycyl-tRNA synthetase 1	Homo sapiens	178-182
2181240-4	1990	A mutation leading to increased permeability of the outer membrane to hydrophobic agents, previously localized to the traT gene, was shown to change a glycine residue to arginine within one of these hydrophobic regions.	Glycine	151-158	TraT	Salmonella enterica subsp. enterica serovar Typhimurium	118-122
15823579-4	2005	By analyzing a series of point mutants of the transmembrane domain, we were also able to identify Gln(192) and Gly(196) as being crucial for the functioning of US11, suggesting that these residues may play a critical role in interacting with the components of the protein degradation machinery.	Glycine	111-114	membrane glycoprotein US11	Human betaherpesvirus 5	160-164
15911376-0	2005	Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor.	Glycine	42-45	tachykinin receptor 1	Homo sapiens	97-110
2195556-8	1990	Silent cholinesterase has a frame shift mutation at glycine 117 which prematurely terminates protein synthesis and yields no active enzyme.	Glycine	52-59	butyrylcholinesterase	Homo sapiens	7-21
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	annexin A7	Homo sapiens	98-105
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	annexin A7	Homo sapiens	98-105
15888962-2	2005	However, it is unclear whether this alkaloid can modulate the function of the N-methyl-D-aspartate (NMDA) receptor on which glycine acts as a co-agonist via strychnine-insensitive glycine binding sites.	Glycine	124-131	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	78-114
15713676-2	2005	pHCl shows nearly identical similarity to glutamate-, glycine-, and histamine-gated ion channels, does however not belong to any of these ion channel types.	Glycine	54-61	pH-sensitive chloride channel 1	Drosophila melanogaster	0-4
33811821-3	2021	We show that glycine amidinotransferase (GATM), the rate-limiting enzyme for creatine synthesis, is upregulated in liver metastases.	Glycine	13-20	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	Mus musculus	41-45
32832866-3	2020	EP2 inhibition by these novel compounds largely decreased the neuronal injury in rat primary hippocampal cultures containing both neurons and glia that were treated with N-methyl-d-aspartate and glycine.	Glycine	195-202	prostaglandin E receptor 2	Rattus norvegicus	0-3
15644323-3	2005	Substitution of the first glycine within the transmembrane GXXXG motif of Aph-1 causes a loss-of-function phenotype in Caenorhabditis elegans.	Glycine	26-33	Gamma-secretase subunit aph-1	Caenorhabditis elegans	74-79
30576235-11	2019	Interestingly, when the Gly between K330/E332 and R3-pCt was mutated (G334A), hTREK-2 was tonic activated with reversed responses to ATP and acidic pHi.	Glycine	24-27	potassium two pore domain channel subfamily K member 10	Homo sapiens	78-85
15611994-8	2005	On the subcellular level, GlyT2-EGFP fluorescence was colocalized extensively with glycine immunoreactivity in somata and dendrites and with both glycine and GlyT2 immunoreactivity in axon terminals, as shown by triple staining at all levels of the neuraxis, confirming the selective expression of the transgene in glycinergic neurons.	Glycine	83-90	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	26-31
15611994-8	2005	On the subcellular level, GlyT2-EGFP fluorescence was colocalized extensively with glycine immunoreactivity in somata and dendrites and with both glycine and GlyT2 immunoreactivity in axon terminals, as shown by triple staining at all levels of the neuraxis, confirming the selective expression of the transgene in glycinergic neurons.	Glycine	146-153	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	26-31
34910602-4	2022	These expansions facilitate the repeat-associated non-ATG initiated translation (RAN translation), producing five dipeptide repeat proteins (DRPs), including Arg-rich poly(PR: Pro-Arg) and poly-(GR: Gly-Arg) peptides.	Glycine	199-202	RAN, member RAS oncogene family	Homo sapiens	81-84
15588104-3	2005	We have investigated consequence of D481N/K483Q double mutation of NR1 subunit from simulation results of (a) glycine bound form (WG), (b) unbound (closed-apo) form (WOG), (c) a double mutated form (DM), and (d) the antagonist (5,7-dichlorokynuric acid) bound form (DCKA).	Glycine	110-117	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	67-70
34910602-4	2022	These expansions facilitate the repeat-associated non-ATG initiated translation (RAN translation), producing five dipeptide repeat proteins (DRPs), including Arg-rich poly(PR: Pro-Arg) and poly-(GR: Gly-Arg) peptides.	Glycine	199-202	ABL proto-oncogene 2, non-receptor tyrosine kinase	Homo sapiens	203-206
1985904-2	1991	As is the case with many other peptide hormones of the brain and intestine, the formation of biologically active gastrin from a glycine-extended processing intermediate occurs via the action of a peptidylglycyl alpha-amidating monooxygenase (PAM).	Glycine	128-135	gastrin	Homo sapiens	113-120
15588724-0	2005	Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	25-30
1652268-2	1991	Here we present evidence that c-Ha-ras (p21(Gly-12)) and its oncogenic mutant T24-ras (p21(Val-12)) selectively induce omega-conotoxin and dihydropyridine-sensitive Ca2+ currents within a few hours after introduction into the cytoplasm of neuroblastoma x glioma hybrid cells.	Glycine	44-47	H3 histone pseudogene 16	Homo sapiens	40-43
1652268-2	1991	Here we present evidence that c-Ha-ras (p21(Gly-12)) and its oncogenic mutant T24-ras (p21(Val-12)) selectively induce omega-conotoxin and dihydropyridine-sensitive Ca2+ currents within a few hours after introduction into the cytoplasm of neuroblastoma x glioma hybrid cells.	Glycine	44-47	H3 histone pseudogene 16	Homo sapiens	87-90
34838542-2	2022	We previously demonstrated that serine and glycine (SG) deprivation causes loss of sphingosine kinase 1 (SK1) in cancer cells, thereby increasing levels of its lipid substrate, sphingosine (Sph), which mediates several adaptive biological responses.	Glycine	43-50	sphingosine kinase 1	Homo sapiens	83-103
34838542-2	2022	We previously demonstrated that serine and glycine (SG) deprivation causes loss of sphingosine kinase 1 (SK1) in cancer cells, thereby increasing levels of its lipid substrate, sphingosine (Sph), which mediates several adaptive biological responses.	Glycine	43-50	sphingosine kinase 1	Homo sapiens	105-108
34858378-10	2021	The mRNA expression level of jejunal zinc transporter 2 (ZNT2) was higher and that of jejunal Bcl-2-associated X protein (Bax) was lower in the Gly-Zn and zinc lactate groups than in the control group (p<0.05).	Glycine	144-147	apoptosis regulator BAX	Sus scrofa	94-120
34858378-10	2021	The mRNA expression level of jejunal zinc transporter 2 (ZNT2) was higher and that of jejunal Bcl-2-associated X protein (Bax) was lower in the Gly-Zn and zinc lactate groups than in the control group (p<0.05).	Glycine	144-147	apoptosis regulator BAX	Sus scrofa	122-125
1652268-4	1991	In cells loaded with p21(Gly-12), the effect occurred after 2 hours and was terminated after 8 hours.	Glycine	25-28	H3 histone pseudogene 16	Homo sapiens	21-24
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	110-113	H3 histone pseudogene 16	Homo sapiens	106-109
15588724-0	2005	Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels.	Glycine	0-7	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	35-40
15588724-5	2005	The glycine-evoked [3H]D-ASP release was halved by NFPS, a selective blocker of GLYT1 transporters, or by Org 25543, a selective GLYT2 blocker, and almost abolished by a mixture of the two, suggesting that activation of GLYT1 and GLYT2 present on glutamatergic terminals triggers the release of [3H]D-ASP.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	80-85
1793483-5	1991	It leads to the substitution of glycine by aspartic acid in the resulting p21 protein, a consistent amino acid substitution found so far in all types of human cancer exhibiting a codon 13-mutated Ki-ras gene.	Glycine	32-39	H3 histone pseudogene 16	Homo sapiens	74-77
15588724-5	2005	The glycine-evoked [3H]D-ASP release was halved by NFPS, a selective blocker of GLYT1 transporters, or by Org 25543, a selective GLYT2 blocker, and almost abolished by a mixture of the two, suggesting that activation of GLYT1 and GLYT2 present on glutamatergic terminals triggers the release of [3H]D-ASP.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	129-134
15588724-5	2005	The glycine-evoked [3H]D-ASP release was halved by NFPS, a selective blocker of GLYT1 transporters, or by Org 25543, a selective GLYT2 blocker, and almost abolished by a mixture of the two, suggesting that activation of GLYT1 and GLYT2 present on glutamatergic terminals triggers the release of [3H]D-ASP.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	220-225
15588724-5	2005	The glycine-evoked [3H]D-ASP release was halved by NFPS, a selective blocker of GLYT1 transporters, or by Org 25543, a selective GLYT2 blocker, and almost abolished by a mixture of the two, suggesting that activation of GLYT1 and GLYT2 present on glutamatergic terminals triggers the release of [3H]D-ASP.	Glycine	4-11	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	230-235
34675267-10	2021	ROC was used to discriminate ALS from CTRL with an AUC of 0.898 (p < 0.001) using 2,4,6-tri-tert-butylbenzenethiol, beta-alanine, glycine, and ethanolamine.	Glycine	130-137	chymotrypsin like	Homo sapiens	38-42
15588724-9	2005	To conclude, transporters for glycine (GLYT1 or/and GLYT2) and for glutamate coexist on the same spinal cord glutamatergic terminals.	Glycine	30-37	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	39-44
15588724-9	2005	To conclude, transporters for glycine (GLYT1 or/and GLYT2) and for glutamate coexist on the same spinal cord glutamatergic terminals.	Glycine	30-37	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	Mus musculus	52-57
2260635-10	1990	The results of these experiments show that attachment and spreading of bovine aortic endothelial and smooth muscle cells depend primarily on the presence of the Arg-Gly-Asp-Ser (RGDS) sequence in the recombinant fibronectin proteins.	Glycine	165-168	fibronectin 1	Bos taurus	212-223
15601840-4	2005	This mutation abolishes the interactions between the hinge regions of Rad18 (Smc6) and Spr18 (Smc5), as does mutation of a conserved glycine in the hinge region of Spr18 (Smc5).	Glycine	133-140	structural maintenance of chromosomes 6	Homo sapiens	77-81
34635505-5	2022	Our data show that FLT3-ITD constitutively activates the STAT5 signaling pathway, which upregulates the expression of glycine amidinotransferase (GATM), the first rate-limiting enzyme of de novo creatine biosynthesis.	Glycine	118-125	signal transducer and activator of transcription 5A	Homo sapiens	57-62
15724445-7	2005	This binding activity appears to be related to a subgroup of the 2xRBD+Glycine rich hnRNP, suggesting functionally distinct properties of these proteins, in agreement with their evolutionary relationship.	Glycine	71-78	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	84-89
34448471-16	2021	Liver expression of metallothionein-1 (MT1) tended to be greater for GLY vs. ZS (P = 0.07).	Glycine	69-72	MT-1	Ovis aries	20-37
34448471-16	2021	Liver expression of metallothionein-1 (MT1) tended to be greater for GLY vs. ZS (P = 0.07).	Glycine	69-72	MT-1	Ovis aries	39-42
34448471-17	2021	Although Zn apparent absorption did not differ between sources (P = 0.71), differences in post-absorptive metabolism may be responsible for greater plasma Zn concentrations and liver MT1 expression for GLY supplemented lambs, suggesting improved bioavailability of GLY relative to ZS.	Glycine	202-205	MT-1	Ovis aries	183-186
1702227-2	1990	Activation of the NMDA receptor requires glycine as well as NMDA or glutamate.	Glycine	41-48	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	18-31
1702227-6	1990	Furthermore, spermine increases the maximum response to NMDA and glycine and acts, at least in part, by increasing the apparent affinity of the NMDA receptor/channel complex for glycine.	Glycine	65-72	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	144-157
1702227-6	1990	Furthermore, spermine increases the maximum response to NMDA and glycine and acts, at least in part, by increasing the apparent affinity of the NMDA receptor/channel complex for glycine.	Glycine	178-185	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	144-157
15485880-3	2004	We have mutated in various combinations Leu(77), Leu(80), and Leu(81) in the N terminus and Gly(217) and Gln(223) in the C terminus of IGF-BP-3.	Glycine	92-95	insulin like growth factor binding protein 3	Homo sapiens	135-143
2177733-7	1990	The present models of mu- and delta-conformations share geometrical similarity with the low-energy structures of Leu-enkephalin and the Tyr-D-Lys-Gly-Phe-analogue.	Glycine	146-149	prodynorphin	Homo sapiens	113-127
15644961-1	2004	Myristoyl-CoA:protein N-myristoyl transferase (NMT; EC 2.3.1.97) acylates the Gly residue abutting the N-terminal Met with a myristic acid following the removal of the Met residue in certain eukaryotic proteins, and in some cases myristoylation is essential to cell growth and survival.	Glycine	78-81	glycylpeptide N-tetradecanoyltransferase 1	Triticum aestivum	22-45
2275749-1	1990	We have synthesized an insulin-like compound, consisting of the B-chain of bovine insulin and an A-chain corresponding to the A-domain of human insulin-like growth factor-I (IGF-I), in which the isoleucine residue normally present in position 2 of the A-domain of IGF-I has been replaced with glycine.	Glycine	293-300	insulin	Bos taurus	23-30
34361714-6	2021	In addition, hydrogen bonding occurred between hypericin and alpha-glucosidase amino acid residues Lys-156, Ser-157, Gly-160, Ser-240, His-280, Asp-242, and Asp-307.	Glycine	117-120	sucrase-isomaltase	Homo sapiens	61-78
15644961-1	2004	Myristoyl-CoA:protein N-myristoyl transferase (NMT; EC 2.3.1.97) acylates the Gly residue abutting the N-terminal Met with a myristic acid following the removal of the Met residue in certain eukaryotic proteins, and in some cases myristoylation is essential to cell growth and survival.	Glycine	78-81	glycylpeptide N-tetradecanoyltransferase 1	Triticum aestivum	47-50
15733436-12	2004	CONCLUSIONS: A novel mutation of FBN1 gene with Glycine to Serine change is responsible for the ectopia lentis patients in a Chinese family.	Glycine	48-55	fibrillin 1	Homo sapiens	33-37
34135628-7	2021	Furthermore, we found that activation of ErbB4 decreased the glycine concentration in the spinal cord, contributing to modulation of mechanical allodynia.	Glycine	61-68	erb-b2 receptor tyrosine kinase 4	Mus musculus	41-46
1975660-6	1990	The NMDA receptor antagonists 2-amino-5-phosphonovalerate (AP5) and ketamine, which bind to the glutamate recognition site and the ion channel, respectively, also blocked the NMDA-mediated [Ca2+]i response; however, glycine or D-serine did not reverse this effect.	Glycine	216-223	adaptor related protein complex 5 subunit beta 1	Homo sapiens	59-62
2173185-5	1990	Substitution of the natural glycine residue by D-arginine residue in position 2 of the enkephalin molecule truncated at the C-terminus increased the mu-receptor binding potency of the tetrapeptide, whereas its delta receptor binding potency declined by more than one order of magnitude.	Glycine	28-35	proenkephalin	Rattus norvegicus	87-97
15331688-0	2004	Bergmann glial GlyT1 mediates glycine uptake and release in mouse cerebellar slices.	Glycine	30-37	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	15-20
2163012-2	1990	The IC50 of the C-5 antagonists for the inhibition of [3H]glycine binding closely paralleled their potency both in displacing NMDA-selective L-[3H]glutamate binding and in negatively modulating (+)-[3H]5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imi ne maleate ([3H]MK-801) binding.	Glycine	54-65	complement C5	Homo sapiens	16-19
2163012-3	1990	Additionally, reduction of glycine binding by the C-5 antagonists was reversed by both NMDA receptor agonists and C-7 competitive NMDA antagonists, providing evidence that the site of action of these C-5 antagonists is the NMDA recognition site, resulting in indirect modulation of the glycine site.	Glycine	27-34	complement C5	Homo sapiens	50-53
2163012-3	1990	Additionally, reduction of glycine binding by the C-5 antagonists was reversed by both NMDA receptor agonists and C-7 competitive NMDA antagonists, providing evidence that the site of action of these C-5 antagonists is the NMDA recognition site, resulting in indirect modulation of the glycine site.	Glycine	27-34	complement C5	Homo sapiens	200-203
2163012-3	1990	Additionally, reduction of glycine binding by the C-5 antagonists was reversed by both NMDA receptor agonists and C-7 competitive NMDA antagonists, providing evidence that the site of action of these C-5 antagonists is the NMDA recognition site, resulting in indirect modulation of the glycine site.	Glycine	286-293	complement C5	Homo sapiens	50-53
2163012-3	1990	Additionally, reduction of glycine binding by the C-5 antagonists was reversed by both NMDA receptor agonists and C-7 competitive NMDA antagonists, providing evidence that the site of action of these C-5 antagonists is the NMDA recognition site, resulting in indirect modulation of the glycine site.	Glycine	286-293	complement C5	Homo sapiens	200-203
2163012-4	1990	These data imply a functional coupling between the NMDA and associated glycine recognition sites and, furthermore, suggest a differential interaction of C-5 and C-7 competitive NMDA antagonists with the NMDA receptor complex.	Glycine	71-78	complement C5	Homo sapiens	153-156
34136101-0	2021	Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments.	Glycine	73-80	serine hydroxymethyltransferase 1	Homo sapiens	13-18
34136101-1	2021	Human serine hydroxymethyltransferase (SHMT) regulates the serine-glycine one carbon metabolism and plays a role in cancer metabolic reprogramming.	Glycine	66-73	serine hydroxymethyltransferase 1	Homo sapiens	6-37
34136101-1	2021	Human serine hydroxymethyltransferase (SHMT) regulates the serine-glycine one carbon metabolism and plays a role in cancer metabolic reprogramming.	Glycine	66-73	serine hydroxymethyltransferase 1	Homo sapiens	39-43
15331688-5	2004	Whole-cell patch-clamp recordings were obtained from Bergmann glia in mice cerebellar slices to determine whether these glia express functional GlyT1 that can mediate both glycine uptake and efflux.	Glycine	172-179	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	144-149
15331688-6	2004	In the presence of a glycine receptor blocker, glycine and a substrate agonist for GlyT1, sarcosine, induced voltage-dependent inward currents that were abolished by removing external Na(+), identifying them as transport currents.	Glycine	21-28	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	83-88
34217162-7	2021	Glycine, serine and threonine metabolism, arginine and proline metabolism, TGF-beta signaling pathway, and pathways in cancer were significantly enriched in DEGs2 and DEGs4.	Glycine	0-7	delta 4-desaturase, sphingolipid 2	Homo sapiens	157-162
1694710-6	1990	Our demonstration of enriched NMDA/glycine-stimulated [3H]TCP binding in stratum radiatum of hippocampal region CA1 but not in cerebellar granule cell layer correlates with electrophysiologic studies that showed NMDA channel ion flux in CA1 but not in cerebellar granule cell layer in adult rats.	Glycine	35-42	carbonic anhydrase 1	Rattus norvegicus	112-115
1694710-6	1990	Our demonstration of enriched NMDA/glycine-stimulated [3H]TCP binding in stratum radiatum of hippocampal region CA1 but not in cerebellar granule cell layer correlates with electrophysiologic studies that showed NMDA channel ion flux in CA1 but not in cerebellar granule cell layer in adult rats.	Glycine	35-42	carbonic anhydrase 1	Rattus norvegicus	237-240
34090290-8	2021	CONCLUSION: Conclusions: Analysis of Arg16Gly polymorphic variants in the beta2-AR gene showed a statistically significant difference in the distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes in patients with BA and apparently healthy individuals due to the higher frequency of Arg/Arg genotype in controls and higher frequency of Gly/Gly genotype in patients with asthma.	Glycine	170-173	adenosine A2a receptor	Homo sapiens	74-82
1970117-8	1990	The locations of cysteine residues flanking the Gly-X-Y repeat regions of rol-6 and sqt-1 are identical, but differ from those in the other collagens.	Glycine	48-51	Cuticle collagen sqt-1	Caenorhabditis elegans	84-89
34090290-8	2021	CONCLUSION: Conclusions: Analysis of Arg16Gly polymorphic variants in the beta2-AR gene showed a statistically significant difference in the distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes in patients with BA and apparently healthy individuals due to the higher frequency of Arg/Arg genotype in controls and higher frequency of Gly/Gly genotype in patients with asthma.	Glycine	179-182	adenosine A2a receptor	Homo sapiens	74-82
15331688-11	2004	Overall, these results demonstrate for the first time that Bergmann glia express functional GlyT1 that can work in reverse at near-physiological ionic and internal glycine conditions in brain slices.	Glycine	164-171	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	92-97
34090290-8	2021	CONCLUSION: Conclusions: Analysis of Arg16Gly polymorphic variants in the beta2-AR gene showed a statistically significant difference in the distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes in patients with BA and apparently healthy individuals due to the higher frequency of Arg/Arg genotype in controls and higher frequency of Gly/Gly genotype in patients with asthma.	Glycine	183-186	adenosine A2a receptor	Homo sapiens	74-82
34090290-8	2021	CONCLUSION: Conclusions: Analysis of Arg16Gly polymorphic variants in the beta2-AR gene showed a statistically significant difference in the distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes in patients with BA and apparently healthy individuals due to the higher frequency of Arg/Arg genotype in controls and higher frequency of Gly/Gly genotype in patients with asthma.	Glycine	336-339	adenosine A2a receptor	Homo sapiens	74-82
34090290-8	2021	CONCLUSION: Conclusions: Analysis of Arg16Gly polymorphic variants in the beta2-AR gene showed a statistically significant difference in the distribution of Arg/Arg, Arg/Gly, and Gly/Gly genotypes in patients with BA and apparently healthy individuals due to the higher frequency of Arg/Arg genotype in controls and higher frequency of Gly/Gly genotype in patients with asthma.	Glycine	340-343	adenosine A2a receptor	Homo sapiens	74-82
2335199-2	1990	The 17O chemical shifts of the Gly-2 and Gly-3 oxygens of a fully protected Leu-enkephalin were measured to be identical in acetone solution.	Glycine	31-34	prodynorphin	Homo sapiens	76-90
2335199-2	1990	The 17O chemical shifts of the Gly-2 and Gly-3 oxygens of a fully protected Leu-enkephalin were measured to be identical in acetone solution.	Glycine	41-44	prodynorphin	Homo sapiens	76-90
15362871-0	2004	Biological activity and ferric ion binding of fragments of glycine-extended gastrin.	Glycine	59-66	gastrin	Homo sapiens	76-83
2317190-3	1990	The endoplasmic-reticulum-associated form of the enzyme contains myristic acid in an amide linkage to its N-terminal glycine [Ozols, Carr &amp; Strittmatter (1984) J. Biol.	Glycine	117-124	arrestin 3	Rattus norvegicus	133-137
15464418-2	2004	The disease is caused by a deficiency of alanine:glyoxylate aminotransferase (AGT) which catalyzes the conversion of glyoxylate to glycine.	Glycine	131-138	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	41-76
2157524-0	1990	D-cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed in Xenopus oocytes.	Glycine	47-54	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	78-91
2157524-1	1990	In the Xenopus oocyte preparation, D-cycloserine (DCS) had the profile of a partial agonist at the glycine modulatory site of the NMDA receptor.	Glycine	99-106	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	130-143
35212448-0	2022	Glycine Acts Through Estrogen Receptor Alpha to Mediate Estrogen Receptor Signaling, Stimulating Osteogenesis and Attenuating Adipogenesis in Ovariectomized Rats.	Glycine	0-7	estrogen receptor 1	Rattus norvegicus	56-73
35212448-3	2022	In this study, we constructed an ovariectomized (OVX) rat model to evaluate the effects of glycine on bone quality estrogen receptor alpha (ERalpha)-deficient BMSCs to explore how glycine mediated ERalpha regulation of the osteogenic and adipogenic differentiation of BMSCs.	Glycine	180-187	estrogen receptor 1	Rattus norvegicus	197-204
35212448-4	2022	Finally, autodock analysis was used to assess the affinity of glycine for ERalpha.	Glycine	62-69	estrogen receptor 1	Rattus norvegicus	74-81
35212448-6	2022	Further docking experiments showed that glycine and ERalpha have a stronger affinity, and finally proved that the impact of glycine could be blocked by ERalpha.	Glycine	40-47	estrogen receptor 1	Rattus norvegicus	152-159
35212448-6	2022	Further docking experiments showed that glycine and ERalpha have a stronger affinity, and finally proved that the impact of glycine could be blocked by ERalpha.	Glycine	124-131	estrogen receptor 1	Rattus norvegicus	52-59
15464418-2	2004	The disease is caused by a deficiency of alanine:glyoxylate aminotransferase (AGT) which catalyzes the conversion of glyoxylate to glycine.	Glycine	131-138	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	78-81
35212448-6	2022	Further docking experiments showed that glycine and ERalpha have a stronger affinity, and finally proved that the impact of glycine could be blocked by ERalpha.	Glycine	124-131	estrogen receptor 1	Rattus norvegicus	152-159
35212448-7	2022	Therefore, we concluded that glycine stimulated osteogenesis and attenuated adipogenesis in OVX rats, a process which may involve the ERalpha-mediated ER signaling pathway.	Glycine	29-36	estrogen receptor 1	Rattus norvegicus	134-141
15341735-0	2004	The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma.	Glycine	8-11	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma	Homo sapiens	72-76
2106270-7	1990	ODC activity of mucosa from isolated gut segments stimulated by luminal glycine (0.1-0.4 M) was enhanced 60-100% by 10 mM putrescine administered luminally.	Glycine	72-79	ornithine decarboxylase 1	Rattus norvegicus	0-3
33794243-0	2021	Rescue of two trafficking-defective variants of the neuronal glycine transporter GlyT2 associated to hyperekplexia.	Glycine	61-68	solute carrier family 6 member 5	Rattus norvegicus	81-86
35625596-3	2022	By enriching LCSCs from spheroid cultures and performing transcriptomic analysis, we determined that alanine-glyoxylate aminotransferase (AGXT), which participates in the metabolism of serine and glycine, was significantly upregulated in spheroid cultures, and its function in LCSCs remains unknown.	Glycine	196-203	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	101-136
15341735-0	2004	The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma.	Glycine	8-11	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma	Homo sapiens	77-85
35625596-3	2022	By enriching LCSCs from spheroid cultures and performing transcriptomic analysis, we determined that alanine-glyoxylate aminotransferase (AGXT), which participates in the metabolism of serine and glycine, was significantly upregulated in spheroid cultures, and its function in LCSCs remains unknown.	Glycine	196-203	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	138-142
33942912-3	2022	Here we draw particular attention to the latest developments for this multifaceted and unusual subunit: from finely-timed expression patterns that correlate with plasticity windows in developing brains or functional hierarchies in the mature brain to new insight onto presynaptic GluN3A-NMDARs, excitatory glycine receptors and behavioural impacts, alongside further connections to a range of brain disorders.	Glycine	306-313	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	280-286
35212811-0	2022	The role of SHMT2 in modulating lipid metabolism in hepatocytes via glycine-mediated mTOR activation.	Glycine	68-75	mechanistic target of rapamycin kinase	Mus musculus	85-89
15252115-7	2004	The localization of VGAT in the cores of A-cell secretory granules, and in the secretory granule membranes in both cell types, indicates novel aspects of the mechanisms for release of glycine and GABA.	Glycine	184-191	solute carrier family 32 member 1	Homo sapiens	20-24
35212811-9	2022	We also showed that glycine activated mTOR/PPARgamma signaling and identified glycine as a mediator of SHMT2-responsive lipid accumulation in hepatocytes.	Glycine	20-27	mechanistic target of rapamycin kinase	Mus musculus	38-42
35212811-10	2022	In conclusion, silencing SHMT2 in hepatocytes ameliorates lipid accumulation via the glycine-mediated mTOR/PPARgamma pathway.	Glycine	85-92	mechanistic target of rapamycin kinase	Mus musculus	102-106
33807656-3	2021	All six beta-type connexins expressed in human epidermis (Cx26, Cx30, Cx30.3, Cx31, Cx31.1 and Cx32) contain a glycine at position 12 (G12).	Glycine	111-118	gap junction protein beta 4	Homo sapiens	70-76
33233834-11	2020	In human hepatoma cell-lines, 2-carbon from glycine was found to be incorporated into deoxythymidine (dTMP, dT + 1), M + 3 species of purines (deoxyadenine, dA and deoxyguanine, dG), and methionine (Met + 1).	Glycine	44-51	granzyme M	Homo sapiens	199-206
15147510-3	2004	Pressure reversibly antagonized potentiation of glycine in alpha1 GlyR by 40-200 mm ethanol, but did not antagonize 10 and 25 mm ethanol in the same oocytes.	Glycine	48-55	adrenoceptor alpha 1D	Homo sapiens	59-65
15064326-0	2004	Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels.	Glycine	146-153	carbonic anhydrase 1	Rattus norvegicus	100-103
34402126-6	2021	Of the 361 compounds detected in the liver, 41 compounds, including amino acids related to the Cit-arginine (Arg) cycle, argininosuccinic acid, Arg, ornithine, and Cit, as well as gamma aminobutyric acid, glycine, histidine, and nicotinamide adenine dinucleotide were abundant in l-Cit-treated livers.	Glycine	205-212	citron rho-interacting serine/threonine kinase	Homo sapiens	282-285
35465096-9	2022	Last, we observed a significant increase in the co-localization of SD4 with GluA1 after glycine induced long-term potentiation (LTP).	Glycine	88-95	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	76-81
34917610-7	2021	Gly supplementation could reduce the ER stress induced by TG by significantly improving the ER levels and significantly downregulating the expression of genes related to ER stress (Xbp1, ATF4, and ATF6).	Glycine	0-3	X-box binding protein 1	Homo sapiens	181-185
15192815-9	2004	A mutation of CGC--&gt;GGC was found at codon 617 in one ABCD1 allele of the third patient"s mother, leading to the glycine for arginine substitution.	Glycine	116-123	ATP binding cassette subfamily D member 1	Homo sapiens	57-62
34917610-7	2021	Gly supplementation could reduce the ER stress induced by TG by significantly improving the ER levels and significantly downregulating the expression of genes related to ER stress (Xbp1, ATF4, and ATF6).	Glycine	0-3	activating transcription factor 6	Homo sapiens	197-201
34785657-3	2021	Here, employing microrheology with optical tweezers, we reveal molecular determinants that govern the viscoelastic behavior of condensates formed by multivalent Arg/Gly-rich sticker-spacer polypeptides and RNA.	Glycine	165-168	ABL proto-oncogene 2, non-receptor tyrosine kinase	Homo sapiens	161-164
35157758-8	2022	Among the IDH-mutated subtypes, we observed high levels of amino acids, especially glycine and 2-aminoadipic acid, in grade 4 glioma, and N-acetyl aspartic acid in low-grade astrocytoma and oligodendroglioma.	Glycine	83-90	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	10-13
35058907-8	2021	Furthermore, UL11 was verified that it could interact with the lipid raft through sucrose density gradient centrifugation and that function correlates with the second glycine of the UL11.	Glycine	167-174	UL11	Anatid alphaherpesvirus 1	13-17
35058907-8	2021	Furthermore, UL11 was verified that it could interact with the lipid raft through sucrose density gradient centrifugation and that function correlates with the second glycine of the UL11.	Glycine	167-174	UL11	Anatid alphaherpesvirus 1	182-186
35187416-9	2022	Compared to the wild-type human PR, there was an increase in the activation of human Gly722Cys PR by11-deoxycortisol and a decrease in activation by corticosterone, which may have been important in selection for the mutation corresponding to the human glycine-722 PR that first evolved in the platypus PR, a basal mammal.	Glycine	252-259	transmembrane protein 37	Homo sapiens	32-34
35187416-9	2022	Compared to the wild-type human PR, there was an increase in the activation of human Gly722Cys PR by11-deoxycortisol and a decrease in activation by corticosterone, which may have been important in selection for the mutation corresponding to the human glycine-722 PR that first evolved in the platypus PR, a basal mammal.	Glycine	252-259	transmembrane protein 37	Homo sapiens	95-97
34718778-6	2022	Biochemical analyses revealed that NFU4 and NFU5 are required for lipoylation of the H proteins of the glycine decarboxylase complex and the E2 subunits of other mitochondrial dehydrogenases, with little impact on Fe-S cluster-containing respiratory complexes or aconitase.	Glycine	103-110	NFU domain protein 4	Arabidopsis thaliana	35-39
34617111-2	2022	Gephyrin (Geph) is the principal scaffolding protein at inhibitory synapses and is essential for postsynaptic clustering of glycine (GlyRs) and GABA type A receptors (GABAARs).	Glycine	124-131	gephyrin	Homo sapiens	0-8
34617111-2	2022	Gephyrin (Geph) is the principal scaffolding protein at inhibitory synapses and is essential for postsynaptic clustering of glycine (GlyRs) and GABA type A receptors (GABAARs).	Glycine	124-131	gephyrin	Homo sapiens	10-14
34578546-2	2021	In this paper, Sm3+ and Nd3+ co-doped CeO2 (SNDC) and pure CeO2 are synthesized via glycine-nitrate process (GNP) and the electro-chemical properties of the nanocrystalline structure electrolyte are investigated using complementary techniques.	Glycine	84-91	mitochondrially encoded NADH dehydrogenase 3	Homo sapiens	24-27
15185439-2	2004	the mutations responsible are located in the CACNA1S gene (type 1) and in the SCN4A gene (type 2), and are all missense mutations where arginine is mostly replaced by histidine or sometimes glycine.	Glycine	190-197	sodium voltage-gated channel alpha subunit 4	Homo sapiens	78-83
34456753-3	2021	The patient had a missense mutation in the glycine and serine-rich domain of TGFBR1 exon 3.	Glycine	43-50	transforming growth factor beta receptor 1	Homo sapiens	77-83
15071506-4	2004	Ufm1 is first cleaved at the C-terminus to expose its conserved Gly residue.	Glycine	64-67	ubiquitin fold modifier 1	Homo sapiens	0-4
15113199-2	2004	Here for the first time we measured the strength of such a bond, using vibrational frequency shifts of a dimeric and nondimeric variants of GPA containing a Gly CD2 label.	Glycine	157-160	CD2 molecule	Homo sapiens	161-164
34187890-0	2021	Alternative splicing of GluN1 gates glycine site-dependent nonionotropic signaling by NMDAR receptors.	Glycine	36-43	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	24-29
15065854-0	2004	Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: the altered structure of a mutant enzyme may form the basis of its diminished catalytic performance.	Glycine	16-19	Dihydrofolate reductase	Escherichia coli	27-50
34187890-1	2021	N-methyl-D-aspartate (NMDA) receptors (NMDARs), a principal subtype of excitatory neurotransmitter receptor, are composed as tetrameric assemblies of two glycine-binding GluN1 subunits and two glutamate-binding GluN2 subunits.	Glycine	154-161	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	170-175
34187890-2	2021	NMDARs can signal nonionotropically through binding of glycine alone to its cognate site on GluN1.	Glycine	55-62	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	92-97
34187890-6	2021	Here, we discovered that glycine priming of recombinant NMDARs critically depends on GluN1 isoforms lacking the N1 cassette; glycine priming is blocked in splice variants containing N1.	Glycine	25-32	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	85-90
15065854-1	2004	The structure and folding of dihydrofolate reductase (DHFR) from Escherichia coli and the mutant G121V-DHFR, in which glycine 121 in the exterior FG loop was replaced with valine, were studied by molecular dynamics simulations and CD and fluorescence spectroscopy.	Glycine	118-125	Dihydrofolate reductase	Escherichia coli	54-58
34187890-9	2021	This nonionotropic signaling by glycine to synaptic NMDARs was prevented in mice we engineered, such that GluN1 obligatorily contained N1.	Glycine	32-39	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	106-111
34187890-12	2021	Our findings reveal a previously unsuspected molecular function for alternative splicing of GluN1 in controlling nonionotropic signaling of NMDARs by activating the glycine site.	Glycine	165-172	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	92-97
15065854-1	2004	The structure and folding of dihydrofolate reductase (DHFR) from Escherichia coli and the mutant G121V-DHFR, in which glycine 121 in the exterior FG loop was replaced with valine, were studied by molecular dynamics simulations and CD and fluorescence spectroscopy.	Glycine	118-125	Dihydrofolate reductase	Escherichia coli	103-107
15027101-4	2004	Glycine was administered at a dose of 0.6 g kg(-1) body weight to rats with alcohol-induced liver injury, which significantly decreased the levels of TBARS and significantly elevated the activities of SOD, CAT, GSH, GPx and GR in the erythrocyte membrane, plasma and hepatocytes as compared to that of untreated alcohol supplemented rats.	Glycine	0-7	glutathione-disulfide reductase	Rattus norvegicus	224-226
34204137-5	2021	Selective targeting of the alpha3 subtype of glycine receptors (GlyRs), which is highly enriched in the superficial layers of the spinal dorsal horn, a key site of nociceptive processing, may help to further narrow down pharmacological intervention on the nociceptive system and increase tolerability.	Glycine	45-52	glycyl-tRNA synthetase 1	Homo sapiens	64-69
14752230-2	2004	GLYT is a key transport protein in the plasma membrane responsible for the Na(2+)-dependent uptake of glycine needed for glutathione biosynthesis.	Glycine	102-109	protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2	Ictalurus punctatus	0-4
34065603-5	2021	The analyses revealed that critical amino acids, namely Gly, Pro, Ala and Trp, were placed at distinct locations in the higher order structure of PPR domains.	Glycine	56-59	PPR1	Homo sapiens	146-149
15222685-2	2004	The most common IRS1 variant, a Gly --&gt; Arg substitution at codon 972 (Arg972 IRS1), is more prevalent among subjects who have features of insulin resistance syndrome associated, or not, with type 2 diabetes in European populations.	Glycine	32-35	insulin receptor substrate 1	Homo sapiens	16-20
34095107-10	2021	Interestingly, PREP disruption inhibited p-ERK and p-p65 and reduced the levels of proinflammatory cytokines in response to endotoxin and proline-glycine-proline, which guided macrophage/neutrophil infiltration in mice fed a HFD for 24 weeks.	Glycine	146-153	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	53-56
15222685-2	2004	The most common IRS1 variant, a Gly --&gt; Arg substitution at codon 972 (Arg972 IRS1), is more prevalent among subjects who have features of insulin resistance syndrome associated, or not, with type 2 diabetes in European populations.	Glycine	32-35	insulin receptor substrate 1	Homo sapiens	81-85
14645455-4	2004	In cells expressing the alpha1 subunit, responses to 200 microm glycine were blocked by 1 microm strychnine but not by 500 microm DCKA.	Glycine	64-71	adrenoceptor alpha 1D	Homo sapiens	24-30
35616651-1	2022	OBJECTIVE: Glycine encephalopathy, also known as nonketotic hyperglycinemia (NKH), is an inherited neurometabolic disorder with variable clinical course and severity, ranging from infantile epileptic encephalopathy to psychiatric disorders.	Glycine	11-18	aminomethyltransferase	Homo sapiens	49-75
14645481-4	2003	This residue (UV: lysine vs blue:asparagine or glutamate) corresponds to amino acid position glycine 90 (G90) in bovine rhodopsin, a site affected in autosomal dominant human congenital night blindness.	Glycine	93-100	rhodopsin	Bos taurus	120-129
35438092-3	2022	The linker of double Gly was used in the connection of RADA16 and the functional oligopeptide region (RAP1 and RAP2).	Glycine	21-24	RAP1A, member of RAS oncogene family	Homo sapiens	102-106
12909616-3	2003	Using adult feline cardiomyocytes, here we report that integrin-interacting Arg-Gly-Asp (RGD) peptides activate S6K1 as observed by band shifting, kinase activity and phosphorylation at Thr-389 and Thr-421/Ser-424 of S6K1, and S6 protein phosphorylation.	Glycine	80-83	ribosomal protein S6 kinase B1	Homo sapiens	112-116
35438092-3	2022	The linker of double Gly was used in the connection of RADA16 and the functional oligopeptide region (RAP1 and RAP2).	Glycine	21-24	RAP2A, member of RAS oncogene family	Homo sapiens	111-115
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	interleukin 1 alpha	Mus musculus	241-249
12909616-3	2003	Using adult feline cardiomyocytes, here we report that integrin-interacting Arg-Gly-Asp (RGD) peptides activate S6K1 as observed by band shifting, kinase activity and phosphorylation at Thr-389 and Thr-421/Ser-424 of S6K1, and S6 protein phosphorylation.	Glycine	80-83	ribosomal protein S6 kinase B1	Homo sapiens	217-221
12967995-2	2003	Gephyrin-based scaffolds participate in the assembly as well as the dynamics of receptor clusters by connecting the cytoplasmic domains of glycine and GABA(A) receptor polypeptides to two cytoskeletal systems, microtubules and microfilaments.	Glycine	139-146	gephyrin	Homo sapiens	0-8
35321878-7	2022	However, a single amino acid replacement (Gly-2 to Ile-2) in PSMalpha21-12 was sufficient to alter FPR2 signaling to include beta-arrestin recruitment, highlighting a key role of Gly-2 in conferring FPR2-biased signaling.	Glycine	179-182	formyl peptide receptor 2	Homo sapiens	99-103
12807887-6	2003	Adhesion to microfibrils and to Arg-Gly-Asp containing fibrillin-1 protein fragments induced signaling events that led to cell spreading, altered cytoskeletal organization, and enhanced extracellular fibrillin-1 deposition.	Glycine	36-39	fibrillin 1	Homo sapiens	55-66
35131263-5	2022	We show that the enzyme only uses Gly-tRNAGly produced by an independent glycyl-tRNA synthetase (GlyRS) to transfer glycine onto the 3beta-OH of Erg, producing Erg-Gly.	Glycine	34-37	glycyl-tRNA synthetase 1	Homo sapiens	73-95
35131263-5	2022	We show that the enzyme only uses Gly-tRNAGly produced by an independent glycyl-tRNA synthetase (GlyRS) to transfer glycine onto the 3beta-OH of Erg, producing Erg-Gly.	Glycine	116-123	glycyl-tRNA synthetase 1	Homo sapiens	73-95
35131263-5	2022	We show that the enzyme only uses Gly-tRNAGly produced by an independent glycyl-tRNA synthetase (GlyRS) to transfer glycine onto the 3beta-OH of Erg, producing Erg-Gly.	Glycine	164-167	glycyl-tRNA synthetase 1	Homo sapiens	73-95
12807887-6	2003	Adhesion to microfibrils and to Arg-Gly-Asp containing fibrillin-1 protein fragments induced signaling events that led to cell spreading, altered cytoskeletal organization, and enhanced extracellular fibrillin-1 deposition.	Glycine	36-39	fibrillin 1	Homo sapiens	200-211
12807887-8	2003	An Arg-Gly-Asp-independent cell adhesion sequence was also identified within fibrillin-1.	Glycine	7-10	fibrillin 1	Homo sapiens	77-88
12807887-10	2003	A375-SM melanoma cells bound Arg-Gly-Asp-containing fibrillin-1 protein fragments mainly through alpha v beta 3, whereas HT1080 cells used mainly alpha 5 beta 1.	Glycine	33-36	fibrillin 1	Homo sapiens	52-63
35138108-0	2022	Cytochrome P450 Monooxygenase for Catalyzing C-42 Hydroxylation of the Glycine-Derived Fragment in Hangtaimycin Biosynthesis.	Glycine	71-78	cytochrome P450 family 20 subfamily A member 1	Homo sapiens	0-29
12930797-1	2003	Glycine acts as a necessary coagonist for glutamate at the NMDA receptor (NMDAR) complex by binding to the strychnine-insensitive glycine-B binding site on the NR1 subunit.	Glycine	0-7	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	59-72
12930797-1	2003	Glycine acts as a necessary coagonist for glutamate at the NMDA receptor (NMDAR) complex by binding to the strychnine-insensitive glycine-B binding site on the NR1 subunit.	Glycine	0-7	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	74-79
35177655-0	2022	Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome.	Glycine	72-75	collagen type IV alpha 3 chain	Homo sapiens	36-42
12930797-1	2003	Glycine acts as a necessary coagonist for glutamate at the NMDA receptor (NMDAR) complex by binding to the strychnine-insensitive glycine-B binding site on the NR1 subunit.	Glycine	0-7	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	160-163
35177655-0	2022	Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome.	Glycine	72-75	collagen type IV alpha 5 chain	Homo sapiens	43-49
35177655-1	2022	Alport syndrome is the commonest inherited kidney disease and nearly half the pathogenic variants in the COL4A3-COL4A5 genes that cause Alport syndrome result in Gly substitutions.	Glycine	162-165	collagen type IV alpha 3 chain	Homo sapiens	105-111
12930797-2	2003	The fact that glycine is normally found in the brain and spinal cord at concentrations that exceed those required to saturate this site has led to the speculation that glycine normally saturates NMDAR-containing synapses in vivo.	Glycine	168-175	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	195-200
35177655-1	2022	Alport syndrome is the commonest inherited kidney disease and nearly half the pathogenic variants in the COL4A3-COL4A5 genes that cause Alport syndrome result in Gly substitutions.	Glycine	162-165	collagen type IV alpha 5 chain	Homo sapiens	112-118
35177655-3	2022	Pathogenic COL4A5 variants affecting Gly in the Leiden Open Variation Database in males with X-linked Alport syndrome were correlated with age at kidney failure (n = 157) and hearing loss diagnosis (n = 80).	Glycine	37-40	collagen type IV alpha 5 chain	Homo sapiens	11-17
12930797-3	2003	However, additional lines of evidence suggest that synaptic glycine may be efficiently regulated in synaptic areas by the glycine transporter type 1 (GlyT1).	Glycine	60-67	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	122-148
35177655-4	2022	Heterozygous pathogenic COL4A3 and COL4A4 variants affecting Gly (n = 304) in autosomal dominant Alport syndrome were correlated with the risk of haematuria in the UK 100,000 Genomes Project.	Glycine	61-64	collagen type IV alpha 3 chain	Homo sapiens	24-30
35177655-6	2022	Pathogenic COL4A5 variants that resulted in a Gly substitution with a highly destabilising residue reduced the median age at kidney failure by 7 years (p = 0.002), and age at hearing loss diagnosis by 21 years (p = 0.004).	Glycine	46-49	collagen type IV alpha 5 chain	Homo sapiens	11-17
12930797-3	2003	However, additional lines of evidence suggest that synaptic glycine may be efficiently regulated in synaptic areas by the glycine transporter type 1 (GlyT1).	Glycine	60-67	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	150-155
35177655-8	2022	Heterozygous pathogenic COL4A3 and COL4A4 variants that resulted in a Gly substitution with a highly destabilising residue (Arg, Val, Glu, Asp, Trp) were associated with an increased risk of haematuria (p = 0.018), and those adjacent to a non-collagenous region were associated with a reduced risk (p = 0.046).	Glycine	70-73	collagen type IV alpha 3 chain	Homo sapiens	24-30
12930797-4	2003	The recent description of a potent and selective GlyT1 inhibitor (N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl]sarcosine [NFPS]) provides a tool for evaluation of the hypothesis that inhibition of GlyT1 may increase synaptic glycine and thereby potentiate NMDAR function in vivo.	Glycine	230-237	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	Mus musculus	49-54
35150347-9	2022	GEO data revealed that gamma-tocotrienol (g-T3), NSC319726, and Casiopeina Cas-II-gly may reduce the expression of, NDUFAF1, CCNB1, DKK1 genes, respectively (P < 0.01).	Glycine	82-85	cyclin B1	Homo sapiens	125-130
12873148-0	2003	A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein.	Glycine	30-37	synuclein alpha	Homo sapiens	120-135
35080872-2	2022	The adsorption of CO2 under flue gas conditions revealed that glycine- and dl-lysine-functionalized MOF-808 (MOF-808-Gly and -dl-Lys) have the highest uptake capacities.	Glycine	62-69	gastrin	Homo sapiens	33-36
12754200-3	2003	Here we used Affymetrix micro-array and Northern analysis to demonstrate that two enzymes involved in conjugation of bile acids to taurine and glycine, namely bile acid-CoA synthetase (BACS) and bile acid-CoA: amino acid N-acetyltransferase (BAT) are induced by FXR in rat liver.	Glycine	143-150	nuclear receptor subfamily 1, group H, member 4	Rattus norvegicus	262-265
35136972-0	2022	Glycine increased ferroptosis via SAM-mediated GPX4 promoter methylation in rheumatoid arthritis.	Glycine	0-7	glutathione peroxidase 4	Mus musculus	47-51
35136972-7	2022	Methylase expression was detected to explore the mechanism behind the effect of glycine on glutathione peroxidase 4 (GPX4) methylation.	Glycine	80-87	glutathione peroxidase 4	Mus musculus	91-115
35136972-7	2022	Methylase expression was detected to explore the mechanism behind the effect of glycine on glutathione peroxidase 4 (GPX4) methylation.	Glycine	80-87	glutathione peroxidase 4	Mus musculus	117-121
12808093-4	2003	In addition, a mutant of PED/PEA-15 featuring the substitution of Ser(116)--&gt;Gly (PED(S116--&gt;G)) showed 10-fold-decreased phosphorylation by Akt.	Glycine	80-83	proliferation and apoptosis adaptor protein 15	Homo sapiens	29-35
12697759-6	2003	Together these inactivating substitutions identified seven NR1 residues (Ile-385, Gln-387, Glu-388, Thr-500, Asn-502, Ala-696, and Val-717) that undergo proximity-induced covalent coupling with specific regions of the bound antagonist and disclose its mode of docking in the glycine binding pocket of the NMDA receptor.	Glycine	275-282	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	59-62
35163207-1	2022	The eukaryotic translation initiation factor 5A (eIF5A) is an evolutionarily conserved protein that binds ribosomes to facilitate the translation of peptide motifs with consecutive prolines or combinations of prolines with glycine and charged amino acids.	Glycine	223-230	eukaryotic translation initiation factor 5A	Homo sapiens	4-47
12767225-7	2003	We show that glycine substitutions at the corresponding conserved amino acid residues of yeast Apn1, i.e., Glu158 and Asp192, abolish the biological function of this enzyme.	Glycine	13-20	DNA-(apurinic or apyrimidinic site) lyase APN1	Saccharomyces cerevisiae S288C	95-99
35163207-1	2022	The eukaryotic translation initiation factor 5A (eIF5A) is an evolutionarily conserved protein that binds ribosomes to facilitate the translation of peptide motifs with consecutive prolines or combinations of prolines with glycine and charged amino acids.	Glycine	223-230	eukaryotic translation initiation factor 5A	Homo sapiens	49-54
35207427-2	2022	It has been shown that the addition to water of either trimethylamine N-oxide (TMAO), glycine, or betaine causes a significant decrease of T(collapse) in the case of a specific ELP.	Glycine	86-93	nuclear receptor subfamily 5 group A member 1	Homo sapiens	177-180
12626499-1	2003	We have previously reported that two highly conserved amino acids in the C-terminal domain of rat insulin-like growth factor-binding protein (IGFBP)-5, Gly(203) and Gln(209), are involved in binding to insulin-like growth factor (IGF)-1.	Glycine	152-155	insulin-like growth factor binding protein 5	Rattus norvegicus	98-150
35207427-4	2022	We show that an alternative approach, grounded in the magnitude of the solvent-excluded volume effect and its temperature dependence (strictly linked to the translational entropy of solvent and co-solute molecules), is able to rationalize the occurrence of ELP collapse in water on raising the temperature, as well as the T(collapse) lowering caused by the addition to water of either TMAO, glycine, or betaine.	Glycine	391-398	nuclear receptor subfamily 5 group A member 1	Homo sapiens	257-260
12626499-1	2003	We have previously reported that two highly conserved amino acids in the C-terminal domain of rat insulin-like growth factor-binding protein (IGFBP)-5, Gly(203) and Gln(209), are involved in binding to insulin-like growth factor (IGF)-1.	Glycine	152-155	insulin-like growth factor 1	Rattus norvegicus	202-236
12626499-7	2003	Furthermore, the equivalent mutations in the C terminus of rat IGFBP-2 (C-Term 2) also results in a significant reduction in IGF-I binding, suggesting that the highly conserved Gly and Gln residues have a conserved IGF-I binding function in all six IGFBPs.	Glycine	177-180	insulin-like growth factor 1	Rattus norvegicus	125-130
12764101-9	2003	The glycine reversal potential in KCC2 knock-out mice differed significantly from that determined in wild-type controls at postnatal day 12 (P12) but not at P3, demonstrating that KCC2 is not active in neonates, despite its early presence.	Glycine	4-11	solute carrier family 12, member 5	Mus musculus	34-38
12834837-2	2003	The investigation, designed to detect substrate-mediated isomerization of pyruvate kinase, has revealed a 15% enhancement of maximal velocity by supplementation of reaction mixtures with 0.1 M proline, glycine or sorbitol.	Glycine	202-209	pyruvate kinase PKLR	Oryctolagus cuniculus	74-89
12746509-3	2003	One of these low abundance proteins, Gly m Bd 30 K, also referred to as P34, is in fact a major (i.e. immunodominant) soybean allergen.	Glycine	37-40	P34 probable thiol protease	Glycine max	72-75
12700631-8	2003	Conversely, cells expressing a dominant-negative mutant of Hsp27, in which three serine residues (15, 78 and 82) were replaced by glycine, were hypersensitive to the effects of IFN-gamma and exhibited a typical apoptotic phenotype.	Glycine	130-137	heat shock protein family B (small) member 1	Homo sapiens	59-64
12631732-4	2003	An extended glycine-rich region of Sis1, composed of a region rich in phenylalanine residues (G/F) and another rich in methionine residues (G/M), is critical for prion maintenance.	Glycine	12-19	type II HSP40 co-chaperone SIS1	Saccharomyces cerevisiae S288C	35-39
12631732-6	2003	However, there is some functional redundancy within the glycine-rich regions of Sis1, because a deletion of the adjacent glycine/methionine (G/M) region was somewhat defective in propagation of [RNQ(+)] as well.	Glycine	56-63	type II HSP40 co-chaperone SIS1	Saccharomyces cerevisiae S288C	80-84
12631732-6	2003	However, there is some functional redundancy within the glycine-rich regions of Sis1, because a deletion of the adjacent glycine/methionine (G/M) region was somewhat defective in propagation of [RNQ(+)] as well.	Glycine	121-128	type II HSP40 co-chaperone SIS1	Saccharomyces cerevisiae S288C	80-84
12358603-6	2003	The TF-mediated protection from chemical modification of V154A indicated that Gly(154) is responsible for this peculiar feature, and suggests that this region, proximal to the heavy chain N-terminus, is directly involved in the conversion of FVII into FVIIa.	Glycine	78-81	coagulation factor III, tissue factor	Homo sapiens	4-6
12540777-5	2003	However, stimulating NPR-C receptor with des-(Gln(18), Ser(19),Gly(20),Leu(21),Gly(22))-ANP fragment 4-23 amide (C-ANP) also increased hepatocyte tolerance to hypoxia.	Glycine	63-66	natriuretic peptide receptor 3	Rattus norvegicus	21-26
12540777-5	2003	However, stimulating NPR-C receptor with des-(Gln(18), Ser(19),Gly(20),Leu(21),Gly(22))-ANP fragment 4-23 amide (C-ANP) also increased hepatocyte tolerance to hypoxia.	Glycine	79-82	natriuretic peptide receptor 3	Rattus norvegicus	21-26
12527723-6	2003	hPAT1 interacted with glycine, L-alanine, L-proline, alpha-aminoisobutyrate (AIB) and gamma-aminobutyrate (GABA), as evidenced from direct transport measurements and from competition experiments with MeAIB as a transport substrate.	Glycine	22-29	solute carrier family 36 member 1	Homo sapiens	0-5
12749761-1	2003	Aphton is developing an anti-gastrin vaccine [Anti-gastrin 17 immunogen, G17DT, Gastrimmune], which neutralises the gastrin 17 hormone and the Gly-G17 hormone.	Glycine	143-146	gastrin	Homo sapiens	29-36
12749761-1	2003	Aphton is developing an anti-gastrin vaccine [Anti-gastrin 17 immunogen, G17DT, Gastrimmune], which neutralises the gastrin 17 hormone and the Gly-G17 hormone.	Glycine	143-146	gastrin	Homo sapiens	51-58
12749761-1	2003	Aphton is developing an anti-gastrin vaccine [Anti-gastrin 17 immunogen, G17DT, Gastrimmune], which neutralises the gastrin 17 hormone and the Gly-G17 hormone.	Glycine	143-146	gastrin	Homo sapiens	51-58
12525257-10	2003	These data indicate that substitution of the penultimate Ala2 in GIP by Gly or Ser confers resistance to plasma DPP IV degradation, resulting in enhanced biological activity, therefore raising the possibility of their use in the treatment of type 2 diabetes.	Glycine	72-75	dipeptidyl peptidase 4	Homo sapiens	112-118
12770560-3	2003	The present study was carried out to determine the pattern of coexistence of the two GAD isoforms in axonal boutons in different laminae of the cord, and also to examine the relation of the GADs to the glycine transporter GLYT2 (a marker for glycinergic axons), since many spinal neurons are thought to use GABA and glycine as co-transmitters.	Glycine	202-209	solute carrier family 6 member 5	Rattus norvegicus	222-227
12599524-5	2002	Amino acid analyses showed significant elevation of glycine without ketosis in serum, cerebrospinal fluid, and urine, which lead us to the diagnosis of late-onset nonketotic hyperglycinemia(NKH).	Glycine	52-59	aminomethyltransferase	Homo sapiens	190-193
12599524-6	2002	NKH is known to be a rare autosomal recessive metabolic disorder primarily caused by deficient activity of various components of the mitochondrial glycine cleavage system.	Glycine	147-154	aminomethyltransferase	Homo sapiens	0-3
12437346-9	2002	In addition, destabilizing glycine mutants in the N-terminal helix are shown to affect the fractional yield of a heme inverted Cyt c isoform.	Glycine	27-34	cytochrome c, somatic	Equus caballus	127-132
12401724-4	2002	We found that glycated LDL (gly-LDL) triggered STAT5 activation, the formation of a prolactin inducible element (PIE)-binding complex containing STAT5, and increased p21(waf) expression through the activation of the receptor for AGE (RAGE).	Glycine	14-17	signal transducer and activator of transcription 5A	Homo sapiens	47-52
12401724-4	2002	We found that glycated LDL (gly-LDL) triggered STAT5 activation, the formation of a prolactin inducible element (PIE)-binding complex containing STAT5, and increased p21(waf) expression through the activation of the receptor for AGE (RAGE).	Glycine	14-17	signal transducer and activator of transcription 5A	Homo sapiens	145-150
12401724-4	2002	We found that glycated LDL (gly-LDL) triggered STAT5 activation, the formation of a prolactin inducible element (PIE)-binding complex containing STAT5, and increased p21(waf) expression through the activation of the receptor for AGE (RAGE).	Glycine	14-17	H3 histone pseudogene 16	Homo sapiens	166-169
12401724-5	2002	We also demonstrated that dm-LDL and gly-LDL, but not n-LDL treatment induced the formation of a stable complex containing the activated STAT5 and RAGE.	Glycine	37-40	signal transducer and activator of transcription 5A	Homo sapiens	137-142
12677197-1	2002	Thioredoxin (Trx) is a small multifunctional protein with a redox active dithiol/disulfide in the active-site sequence Cys-Gly-Pro-Cys.	Glycine	123-126	thioredoxin	Homo sapiens	0-11
12677197-1	2002	Thioredoxin (Trx) is a small multifunctional protein with a redox active dithiol/disulfide in the active-site sequence Cys-Gly-Pro-Cys.	Glycine	123-126	thioredoxin	Homo sapiens	13-16
12499702-2	2002	A Gly and Asp substitution at position 169 of the mouse Nramp protein is invariably associated with the resistant and susceptible phenotypes, respectively.	Glycine	2-5	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	Mus musculus	56-61
12499702-7	2002	All the breeds of cattle and buffaloes tested in this study coded for Gly at the position in exon VI which corresponds to the same amino acid of the murine Nramp1-resistant phenotype at position 169.	Glycine	70-73	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	Mus musculus	156-162
12379104-2	2002	The influence of the distal Gly-121 residue on the chemical step of hydride transfer in dihydrofolate reductase (DHFR) catalysis had been demonstrated previously [Cameron, C. E., and Benkovic, S. J.	Glycine	28-31	dihydrofolate reductase	Homo sapiens	88-111
12379104-2	2002	The influence of the distal Gly-121 residue on the chemical step of hydride transfer in dihydrofolate reductase (DHFR) catalysis had been demonstrated previously [Cameron, C. E., and Benkovic, S. J.	Glycine	28-31	dihydrofolate reductase	Homo sapiens	113-117
12161434-6	2002	Increases in cSHMT expression inhibit SAM concentrations by two proposed mechanisms: (1) cSHMT-catalyzed serine synthesis competes with the enzyme methylenetetrahydrofolate reductase for methylenetetrahydrofolate in a glycine-dependent manner, and (2) cSHMT, a high affinity 5-methyltetrahydrofolate-binding protein, sequesters this cofactor and inhibits methionine synthesis in a glycine-independent manner.	Glycine	218-225	serine hydroxymethyltransferase 1	Homo sapiens	13-18
12161434-6	2002	Increases in cSHMT expression inhibit SAM concentrations by two proposed mechanisms: (1) cSHMT-catalyzed serine synthesis competes with the enzyme methylenetetrahydrofolate reductase for methylenetetrahydrofolate in a glycine-dependent manner, and (2) cSHMT, a high affinity 5-methyltetrahydrofolate-binding protein, sequesters this cofactor and inhibits methionine synthesis in a glycine-independent manner.	Glycine	218-225	serine hydroxymethyltransferase 1	Homo sapiens	89-94
12161434-6	2002	Increases in cSHMT expression inhibit SAM concentrations by two proposed mechanisms: (1) cSHMT-catalyzed serine synthesis competes with the enzyme methylenetetrahydrofolate reductase for methylenetetrahydrofolate in a glycine-dependent manner, and (2) cSHMT, a high affinity 5-methyltetrahydrofolate-binding protein, sequesters this cofactor and inhibits methionine synthesis in a glycine-independent manner.	Glycine	218-225	serine hydroxymethyltransferase 1	Homo sapiens	89-94
12381362-8	2002	Mono S chromatography of 2 out of 26 individual human whey samples showed a rare polymorphic hLF variant with three N-terminal arginines (Gly(1)-Arg(2)-Arg(3)-Arg(4)-Ser(5)-) instead of the usual variant with four N-terminal arginines (Gly(1)-Arg(2)-Arg(3)-Arg(4)-Arg(5)-Ser(6)-).	Glycine	138-141	HLF transcription factor, PAR bZIP family member	Homo sapiens	93-96
12381362-8	2002	Mono S chromatography of 2 out of 26 individual human whey samples showed a rare polymorphic hLF variant with three N-terminal arginines (Gly(1)-Arg(2)-Arg(3)-Arg(4)-Ser(5)-) instead of the usual variant with four N-terminal arginines (Gly(1)-Arg(2)-Arg(3)-Arg(4)-Arg(5)-Ser(6)-).	Glycine	236-239	HLF transcription factor, PAR bZIP family member	Homo sapiens	93-96
12095981-4	2002	Rhodamine 110 (R110), a highly fluorescent xanthene dye, was used to synthesize dipeptidyl peptidase IV (DP IV/CD26) substrates Gly(Ala)-Pro-R110-R, thus facilitating a stable binding of the fluorescent moiety on the cell surface.	Glycine	128-131	dipeptidyl peptidase 4	Homo sapiens	80-103
12095981-4	2002	Rhodamine 110 (R110), a highly fluorescent xanthene dye, was used to synthesize dipeptidyl peptidase IV (DP IV/CD26) substrates Gly(Ala)-Pro-R110-R, thus facilitating a stable binding of the fluorescent moiety on the cell surface.	Glycine	128-131	dipeptidyl peptidase 4	Homo sapiens	105-110
12095981-4	2002	Rhodamine 110 (R110), a highly fluorescent xanthene dye, was used to synthesize dipeptidyl peptidase IV (DP IV/CD26) substrates Gly(Ala)-Pro-R110-R, thus facilitating a stable binding of the fluorescent moiety on the cell surface.	Glycine	128-131	dipeptidyl peptidase 4	Homo sapiens	111-115
12115135-5	2002	Analysis of the Gly carbonyl oxygens and terminal groups indicated that, while the conformational population distribution of Leu enkephalin did vary noticeably as a function of pH, their hydration was essentially independent of pH and in agreement with the available NMR data.	Glycine	16-19	prodynorphin	Homo sapiens	125-139
12112533-5	2002	The NUP98-HOXA13 fusion protein consists of the N-terminal phenylalanine-glycine repeat motif of NUP98 and the C-terminal homeodomain of HOXA13, similar to the NUP98-HOXA9 fusion protein.	Glycine	73-80	homeobox A13	Homo sapiens	10-16
12151550-2	2002	We previously have described two mouse lines carrying point mutations in the NMDA receptor glycine binding site, Grin1(D481N) and Grin1(K483Q), which exhibit 5- and 86-fold reductions in receptor glycine affinity, respectively.	Glycine	91-98	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	113-118
12151550-2	2002	We previously have described two mouse lines carrying point mutations in the NMDA receptor glycine binding site, Grin1(D481N) and Grin1(K483Q), which exhibit 5- and 86-fold reductions in receptor glycine affinity, respectively.	Glycine	91-98	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	130-135
12151550-2	2002	We previously have described two mouse lines carrying point mutations in the NMDA receptor glycine binding site, Grin1(D481N) and Grin1(K483Q), which exhibit 5- and 86-fold reductions in receptor glycine affinity, respectively.	Glycine	196-203	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	113-118
12151550-2	2002	We previously have described two mouse lines carrying point mutations in the NMDA receptor glycine binding site, Grin1(D481N) and Grin1(K483Q), which exhibit 5- and 86-fold reductions in receptor glycine affinity, respectively.	Glycine	196-203	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	130-135
11950837-7	2002	Gly-456 lies in a very tightly packed region of the GDH molecule, and its replacement by Ala may lead to steric clashes with neighboring amino acids.	Glycine	0-3	glutamate dehydrogenase 1	Homo sapiens	52-55
12144936-3	2002	The functional coupling of mu-opioid receptors to G proteins was determined autoradiographically using Tyr-D-Ala-Gly-N(Me)Phe-Gly-ol-enkephalin-stimulated [35S]GTPgammaS binding in brain cryostat sections.	Glycine	113-116	proenkephalin	Rattus norvegicus	133-143
12115694-3	2002	Furthermore, the vesicular inhibitory amino acid transporter (VIAAT or VGAT) that loads GABA and glycine into synaptic vesicles was reported recently to be expressed in horizontal cells.	Glycine	97-104	solute carrier family 32 member 1	Homo sapiens	62-67
12115694-3	2002	Furthermore, the vesicular inhibitory amino acid transporter (VIAAT or VGAT) that loads GABA and glycine into synaptic vesicles was reported recently to be expressed in horizontal cells.	Glycine	97-104	solute carrier family 32 member 1	Homo sapiens	71-75
12091465-3	2002	Functional analysis of the GFP-GLYT1 and GFP-GLYT2 stable cell lines demonstrated that they exhibited high affinity for glycine and the characteristic properties of both glycine transporter subtypes.	Glycine	120-127	solute carrier family 6 member 5	Rattus norvegicus	45-50
11943775-6	2002	The proline 180 and glycine 181 residues in the extracellular domain of CD147 were critical for signaling and chemotactic activities mediated by CD147.	Glycine	20-27	basigin (Ok blood group)	Homo sapiens	72-77
11943775-6	2002	The proline 180 and glycine 181 residues in the extracellular domain of CD147 were critical for signaling and chemotactic activities mediated by CD147.	Glycine	20-27	basigin (Ok blood group)	Homo sapiens	145-150
12068077-2	2002	The inhibition constants (K (I) s) for the binding of l-glutamate and glycine to NR1-1a/NR2A determined by [3 H]CGP 39653 and [3 H]MDL 105 519 displacement assays, respectively, were not significantly different between NR1-1a/NR2A receptors coexpressed +/- PSD-95(c-Myc).	Glycine	70-77	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	264-269
12009900-8	2002	Examination of various compounds with Ava in positions 9,10 and/or 14,15 revealed that the Leu(9)-Gly(10) and Arg(14)-Pro(15) segments of the disulfide ring are the principal structural elements determining hMCH-1R selectivity and ability to act as a hMCH-1R antagonist.	Glycine	98-101	melanin concentrating hormone receptor 1	Homo sapiens	207-214
12009900-8	2002	Examination of various compounds with Ava in positions 9,10 and/or 14,15 revealed that the Leu(9)-Gly(10) and Arg(14)-Pro(15) segments of the disulfide ring are the principal structural elements determining hMCH-1R selectivity and ability to act as a hMCH-1R antagonist.	Glycine	98-101	melanin concentrating hormone receptor 1	Homo sapiens	251-258
12062426-2	2002	In the present study, we investigated the activity of P53(gly(281)) in P53-null PC3 human prostate cancer cells and found that the P53(gly(281)) induced apoptosis as efficiently as the wild-type P53 (wtP53).	Glycine	58-61	proprotein convertase subtilisin/kexin type 1	Homo sapiens	80-83
11927375-1	2002	The specificity of the orphaninFQ (OFQ)/nociceptin (N)-induced prolactin increase was determined in male and female rats by pretreating animals with different doses of [Phe(1)Psi(CH(2)-NH)Gly(2)]NC(1-13)NH(2), a compound originally reported to be a specific OFQ/N antagonist.	Glycine	188-191	prepronociceptin	Rattus norvegicus	40-50
2614645-1	1989	A novel inhibitor of angiotensin-converting enzyme (ACE) derived from tuna muscle, Pro-Thr-His-Ile-Lys-Trp-Gly-Asp (tuna AI), was chemically synthesized, and its biological properties were investigated.	Glycine	107-110	angiotensin-converting enzyme	Oryctolagus cuniculus	52-55
2669516-3	1989	The amino acid sequence of this peptide is H-Gly-Asn-Trp-Ala-Ala-Gly-His-Leu-Met-NH2 ([Ala6]GRP-10).	Glycine	43-48	gastrin releasing peptide	Homo sapiens	92-98
11840480-0	2002	Glycine and GABA(A) receptor subunits on Renshaw cells: relationship with presynaptic neurotransmitters and postsynaptic gephyrin clusters.	Glycine	0-7	gephyrin	Homo sapiens	121-129
11840480-2	2002	We investigated the presynaptic inhibitory neurotransmitter content (GABA, glycine, or both) and the presence and subunit composition of GABA(A) and glycine postsynaptic receptors in one example of gephyrin-rich synapses to determine neurochemical characteristics that could also contribute to enhance synaptic strength.	Glycine	75-82	gephyrin	Homo sapiens	198-206
2675963-9	1989	Glycine is by far the most conserved residue and corresponds to positions at bends in the conformation of the alcohol dehydrogenase.	Glycine	0-7	aldo-keto reductase family 1 member A1	Homo sapiens	110-131
11875045-4	2002	We recently mapped an autosomal semi-dominant cataract [lens opacity 10 (Lop10)] mutation to mouse chromosome 3 and identified a missense mutation (G--&gt;C) in the Gja8 gene, which causes glycine at codon 22 to be replaced with arginine (G22R).	Glycine	189-196	gap junction protein, alpha 8	Mus musculus	73-78
2742826-2	1989	At pH 5.3 and 25 degrees C, the Arg(16)-Gly(17) peptide bonds of both peptides F10 and F13 were cleaved instantaneously in the presence of 0.6 mM thrombin, whereas the cleavage of the Arg(19)-Val(20) peptide bonds in peptides F12, F13, and F14 took over 1 h for completion.	Glycine	40-43	coagulation factor XII	Homo sapiens	226-229
3238653-5	1988	These studies suggest that the glycoprotein IIb-IIIa complex on activated platelets may interact with vitronectin substrate through the Arg-Gly-Asp mechanism.	Glycine	140-143	vitronectin	Homo sapiens	102-113
11875045-4	2002	We recently mapped an autosomal semi-dominant cataract [lens opacity 10 (Lop10)] mutation to mouse chromosome 3 and identified a missense mutation (G--&gt;C) in the Gja8 gene, which causes glycine at codon 22 to be replaced with arginine (G22R).	Glycine	189-196	gap junction protein, alpha 8	Mus musculus	165-169
11861317-7	2002	Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors.	Glycine	46-53	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	87-90
3264556-9	1988	The Arg-Gly-Asp cell recognition sequence is present in one of the EGF-type repeats, and a synthetic peptide from the putative cell-binding site of entactin was found to promote the attachment of mouse mammary tumor cells.	Glycine	8-11	nidogen 1	Mus musculus	148-156
11861317-7	2002	Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors.	Glycine	46-53	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	87-90
11772442-8	2002	The maximum amplitude of glycine-evoked currents was reliably dependent on the percentage of alpha 1-containing plasmid.	Glycine	25-32	adrenoceptor alpha 1D	Homo sapiens	93-100
3053736-7	1988	Although different in activation pathways and recognition specificity, Mac-1 exhibits an oligospecific ligand versatility characteristic of other homologous Arg-Gly-Asp-directed adhesion receptors.	Glycine	161-164	integrin subunit alpha M	Homo sapiens	71-76
11772442-9	2002	Optimum results for steady-state single channel experiments at low glycine concentrations were obtained with 5% of alpha 1 plasmid DNA in the transfection mix.	Glycine	67-74	adrenoceptor alpha 1D	Homo sapiens	115-122
11743879-9	2002	A flexible glycine-rich region is followed by these 15 residues in the Ssa1 primary sequence.	Glycine	11-18	Hsp70 family ATPase SSA1	Saccharomyces cerevisiae S288C	71-75
2841473-6	1988	The gag polyprotein of mammalian type C retrovirus contains myristic acid covalently linked to the N-terminal glycine.	Glycine	110-117	endogenous retrovirus group K member 9	Homo sapiens	4-19
11875968-4	2002	The a and b reaction orders were close to 1/2 and 3/2 for Xaa = Ala, Val, Phe, Ser, or Leu, 1/2 and 1 for Gly, Met, or Pro, and 1 and 2 for Ile.	Glycine	106-109	deleted in lymphocytic leukemia 1	Homo sapiens	87-101
2900138-6	1988	T1 is related to TC1, and has the structure: Ser-Ser(P)-Met-Ser-Gly-Leu-His-Leu-Val-Lys.	Glycine	64-67	Serum cholesterol level QTL 22	Rattus norvegicus	17-20
3282511-0	1988	Rapid and transient induction of c-fos, c-myc and c-Ha-ras in rat liver following glycine administration.	Glycine	82-89	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	33-38
11698233-4	2001	When expressed in Xenopus laevis oocytes and in mammalian cells, rat SN2 mediates Na(+)-dependent transport of several neutral amino acids, including glycine, asparagine, alanine, serine, glutamine, and histidine.	Glycine	150-157	solute carrier family 38, member 5	Rattus norvegicus	69-72
3282511-4	1988	The rapid rise and decline in the mRNA levels of c-fos, c-myc and c-Ha-ras in response to glycine is of significance because in response to a wide variety of growth stimuli, these proto-oncogenes exhibit a temporal sequence in their expression; for example, the expression of c-fos precedes that of c-myc, which in turn precedes the increased expression of c-Ha-ras.	Glycine	90-97	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	49-54
3282511-4	1988	The rapid rise and decline in the mRNA levels of c-fos, c-myc and c-Ha-ras in response to glycine is of significance because in response to a wide variety of growth stimuli, these proto-oncogenes exhibit a temporal sequence in their expression; for example, the expression of c-fos precedes that of c-myc, which in turn precedes the increased expression of c-Ha-ras.	Glycine	90-97	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	276-281
3346666-9	1988	The present data therefore demonstrate that milacemide is a substrate for brain MAO-B, and its conversion to glycinamide, further transformed to the inhibitory neurotransmitter, glycine, mediated by this enzyme may contribute to its pharmacological activities.	Glycine	178-185	monoamine oxidase B	Homo sapiens	80-85
3288862-8	1988	We found that cells expressing elevated levels of the normal p21(H-ras) could be fully transformed by the activated (Val-12) form and that such cells continued to overexpress p21(H-ras) (Gly-12), arguing against a role for normal ras genes in suppression of the oncogenic potential of their mutationally activated counterparts.	Glycine	187-190	KRAS proto-oncogene, GTPase	Rattus norvegicus	175-178
2531294-7	1989	The use of site-directed antibodies implicates a small region of alpha- and beta-tubulin, containing the sequence Glu-Gly-Glu-Glu, as the site of the interaction of dynein and MAP2 with the microtubule.	Glycine	118-121	microtubule associated protein 2	Homo sapiens	176-180
11721009-0	2001	Molecular dynamics simulations of Gly-12--&gt;Val mutant of p21(ras): dynamic inhibition mechanism.	Glycine	34-37	H3 histone pseudogene 16	Homo sapiens	60-63
2572591-5	1989	Here we demonstrate that the mutation in the type II procollagen gene is a single base change that converts the codon for glycine (GGC) at amino acid 943 of the alpha 1 (II) chain to a codon for serine (AGC).	Glycine	122-129	gamma-glutamylcyclotransferase	Homo sapiens	131-134
11724748-2	2001	The regulation of glycine concentrations within excitatory synapses is poorly understood and it has been proposed that the GLYT1 subtypes of glycine transporters play a critical role in determining resting concentrations of glycine.	Glycine	18-25	solute carrier family 6 member 9 L homeolog	Xenopus laevis	123-128
2549064-5	1989	There is a smaller reduction in GTPase activity in another mutant in which valine replaces glycine 49 (corresponding to glycine 12 of p21ras).	Glycine	91-98	Harvey rat sarcoma virus oncogene	Mus musculus	134-140
11724748-2	2001	The regulation of glycine concentrations within excitatory synapses is poorly understood and it has been proposed that the GLYT1 subtypes of glycine transporters play a critical role in determining resting concentrations of glycine.	Glycine	141-148	solute carrier family 6 member 9 L homeolog	Xenopus laevis	123-128
11724748-3	2001	Selective GLYT1 inhibitors may provide pharmacological tools to probe the dynamics of synaptic glycine concentrations, which may influence the activation properties of NMDA receptor activity.	Glycine	95-102	solute carrier family 6 member 9 L homeolog	Xenopus laevis	10-15
11724748-3	2001	Selective GLYT1 inhibitors may provide pharmacological tools to probe the dynamics of synaptic glycine concentrations, which may influence the activation properties of NMDA receptor activity.	Glycine	95-102	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	168-181
2753902-1	1989	The platelet glycoprotein IIb-IIIa complex (GP IIb-IIIa) is a member of the integrin receptor family that recognizes adhesive proteins containing the Arg-Gly-Asp (RGD) sequence.	Glycine	154-157	integrin subunit alpha 2b	Homo sapiens	44-50
2450354-1	1988	The sequence Lys-Ser-Pro-Val-Pro-Lys-Ser-Pro-Val-Glu-Glu-Lys-Gly repeats six times serially in the human midsized neurofilament (NF) protein (NF-M).	Glycine	61-64	neurofilament medium chain	Homo sapiens	142-146
11746430-7	2001	In the presence of an activity-inhibiting antiserum against ApN the utilization of CysGly as neuronal glutathione precursor was completely prevented, whereas that of cysteine plus glycine was not affected.	Glycine	180-187	alanyl aminopeptidase, membrane	Rattus norvegicus	60-63
2835228-3	1988	The putative protein encoded by mst(3)gl-9 is mostly composed of repetitive Cys-Gly-Pro motifs.	Glycine	80-83	Male-specific RNA 87F	Drosophila melanogaster	32-42
2504277-8	1989	Additional screening of the library with a trypsinogen cDNA led to the isolation and sequencing of a full-length clone apparently coding for the complete sequence of a second tryptic serine protease (DMP) which is only 53.4% identical with the dog tryptase sequence but which contains an apparent signal/activation peptide also terminating in a glycine.	Glycine	345-352	chymase 1	Canis lupus familiaris	183-198
2708912-8	1989	It is shown in addition that the tripeptide Arg-Gly-Asp, identical to the region of iC3b recognized by CR3 and by several adhesion-promoting receptors that are structurally similar to CR3, such as fibronectin or vitronectin, is a significant inhibitor of the binding to and the phagocytosis of S-RBC by monocytic-macrophagic cells.	Glycine	48-51	vitronectin	Homo sapiens	212-223
2742827-2	1989	At pH 5.3 and 25 degrees C, the Arg(16)-Gly(17) peptide bonds in both F6 and F8 were cleaved instantaneously in the presence of 0.5 mM thrombin, producing truncated peptides tF6 and tF8 and other peptide fragments.	Glycine	40-43	trafficking from ER to golgi regulator	Homo sapiens	174-177
11809931-4	2001	The CD2 variant with two Gly linkers has been shown to have the strongest metal binding affinity to Ca(II) and La(III).	Glycine	25-28	CD2 molecule	Homo sapiens	4-7
2539883-2	1989	The results indicate that strychnine-insensitive glycine binding sites are present in high concentrations in CA1 and the molecular layer of the dentate gyrus.	Glycine	49-56	carbonic anhydrase 1	Homo sapiens	109-112
3278172-5	1988	A point mutation of the 12th codon (GGT to GAT) resulting in aspartic acid substitution for glycine was observed.	Glycine	92-99	glycine-N-acyltransferase	Homo sapiens	43-46
11546761-8	2001	We hypothesize that the hinge formed by the conserved Gly(206) on beta-strand s3A in the breach region of PAI-2 effects the S --&gt; R transition by altering its backbone torsion angles.	Glycine	54-57	serpin family B member 2	Homo sapiens	106-111
2446681-1	1988	An arginine-glycine-aspartic acid sequence (RGD in the single letter code for amino acids) is present in the cell attachment site of both vitronectin and fibronectin.	Glycine	12-19	vitronectin	Ovis aries	138-149
2542205-2	1989	Among 34 tissues specimens surgically resected from 30 patients and 5 cell lines of human HCC, only two had ras point mutations; in one case, codon 12 of c-Ki-ras was altered from GGT, coding glycine, to GTT, coding valine; in the other case, codon 61 of N-ras was altered from CAA, coding glutamine, to AAA, coding lysine.	Glycine	192-199	KRAS proto-oncogene, GTPase	Homo sapiens	154-162
11709067-4	2001	We found that GLYT2 is rapidly trafficked first towards the plasma membrane and then internalized under conditions that stimulate vesicular glycine release.	Glycine	140-147	solute carrier family 6 member 5	Rattus norvegicus	14-19
2722396-0	1989	Analogs of oxytocin containing a pseudopeptide Leu-Gly bond of cis and trans configuration.	Glycine	51-54	oxytocin/neurophysin I prepropeptide	Homo sapiens	11-19
2722396-1	1989	Analogs of deamino-oxytocin wherein the Leu-Gly peptide bond has been replaced by a tetrazole moiety or by a double bond of trans configuration were synthesized and their biological activities evaluated.	Glycine	44-47	oxytocin/neurophysin I prepropeptide	Homo sapiens	19-27
2826659-6	1988	The order of putative signal sequences and stop transfer sequences indicated that KUN NS1, NS2A and NS4B are probably cleaved in the lumen of the endoplasmic reticulum, at a consensus site Val-X-Ala decreases where X is an uncharged residue, and NS2B, NS3 and NS5 are cleaved in the cytosol at the site Lys-Arg decreases Gly.	Glycine	321-324	influenza virus NS1A binding protein	Homo sapiens	86-89
3436060-6	1987	The activity of prolidase II, which was eluted in high ionic strength fractions of about 260 mmol/l NaCl during DEAE-Sephadex chromatography, diminished markedly after preincubation and was very low against the gly-pro substrate.	Glycine	211-214	peptidase D	Homo sapiens	16-25
2710278-7	1989	The cellular origin of the P1 and P2 synaptosomal fractions releasing glycine is discussed.	Glycine	70-77	crystallin gamma F, pseudogene	Homo sapiens	27-36
2470110-1	1989	The disialogangliosides GD2 and GD3 play a major role in the ability of human melanoma cells to attach to Arg-Gly-Asp-containing substrates such as fibronectin and vitronectin, since pretreatment of these cells with monoclonal antibodies to the oligosaccharide of GD2 and GD3 can inhibit their attachment and spreading on such adhesive proteins.	Glycine	110-113	vitronectin	Homo sapiens	164-175
2470110-2	1989	This report demonstrates that human melanoma cells (M21) synthesize and express a glycoprotein receptor that shares antigenic epitopes with the vitronectin receptor on human fibroblasts and is capable of specifically recognizing the Gly-Arg-Gly-Asp-Ser-Pro sequence.	Glycine	233-236	vitronectin	Homo sapiens	144-155
29712138-2	2001	It is important for the inhibition of cell adhesion that the arabino sialyl Lewisx glycopeptide 1, which contains the Gly 672 -Asp 681 sequence of the E-selectin Ligand 1 (ESL-1), binds ten times more strongly than sialyl Lewisx to E-selectin, although it is monovalent and does not contain L-fucose, which is considered essential.	Glycine	118-121	golgi glycoprotein 1	Homo sapiens	151-170
3186727-6	1988	HPLC analysis of fragments formed upon incubation of exogenous CCK-8 [CCK-(26-33)-octapeptide] with brain slices showed CCK-5, Gly-Trp-Met, and Trp-Met to be major metabolites of CCK-8 whose formation was prevented or at least diminished in the presence of the elastase inhibitor.	Glycine	127-130	cholecystokinin	Rattus norvegicus	63-66
3186727-6	1988	HPLC analysis of fragments formed upon incubation of exogenous CCK-8 [CCK-(26-33)-octapeptide] with brain slices showed CCK-5, Gly-Trp-Met, and Trp-Met to be major metabolites of CCK-8 whose formation was prevented or at least diminished in the presence of the elastase inhibitor.	Glycine	127-130	cholecystokinin	Rattus norvegicus	70-73
3312423-6	1987	The amino acid composition of the purified HSP included 30% glycine, 15% serine, 12% glutamic acid, and 4% ornithine, but only 2.3% histidine.	Glycine	60-67	heat shock protein 90 beta family member 2, pseudogene	Homo sapiens	43-46
29712138-2	2001	It is important for the inhibition of cell adhesion that the arabino sialyl Lewisx glycopeptide 1, which contains the Gly 672 -Asp 681 sequence of the E-selectin Ligand 1 (ESL-1), binds ten times more strongly than sialyl Lewisx to E-selectin, although it is monovalent and does not contain L-fucose, which is considered essential.	Glycine	118-121	golgi glycoprotein 1	Homo sapiens	172-177
3186727-6	1988	HPLC analysis of fragments formed upon incubation of exogenous CCK-8 [CCK-(26-33)-octapeptide] with brain slices showed CCK-5, Gly-Trp-Met, and Trp-Met to be major metabolites of CCK-8 whose formation was prevented or at least diminished in the presence of the elastase inhibitor.	Glycine	127-130	cholecystokinin	Rattus norvegicus	70-73
3186727-6	1988	HPLC analysis of fragments formed upon incubation of exogenous CCK-8 [CCK-(26-33)-octapeptide] with brain slices showed CCK-5, Gly-Trp-Met, and Trp-Met to be major metabolites of CCK-8 whose formation was prevented or at least diminished in the presence of the elastase inhibitor.	Glycine	127-130	cholecystokinin	Rattus norvegicus	70-73
2443507-1	1987	The disialogangliosides GD2 and GD3 play a major role in the ability of human melanoma cells to attach to Arg-Gly-Asp-containing substrates such as fibronectin and vitronectin, since pretreatment of these cells with monoclonal antibodies to the oligosaccharide of GD2 and GD3 can inhibit their attachment and spreading on such adhesive proteins.	Glycine	110-113	vitronectin	Homo sapiens	164-175
2443507-2	1987	This report demonstrates that human melanoma cells (M21) synthesize and express a glycoprotein receptor that shares antigenic epitopes with the vitronectin receptor on human fibroblasts and is capable of specifically recognizing the Gly-Arg-Gly-Asp-Ser-Pro sequence.	Glycine	233-236	vitronectin	Homo sapiens	144-155
29712138-2	2001	It is important for the inhibition of cell adhesion that the arabino sialyl Lewisx glycopeptide 1, which contains the Gly 672 -Asp 681 sequence of the E-selectin Ligand 1 (ESL-1), binds ten times more strongly than sialyl Lewisx to E-selectin, although it is monovalent and does not contain L-fucose, which is considered essential.	Glycine	118-121	selectin E	Homo sapiens	151-161
11641236-9	2001	Several polymorphisms in the IRS genes have been identified, but only the Gly--&gt;Arg972 substitution of IRS-1, interacting with environmental factors, seems to have a pathogenic role in the development of type 2 diabetes.	Glycine	74-77	insulin receptor substrate 1	Homo sapiens	106-111
3596169-1	1987	Recently, glycine-extended processing intermediates of progastrin were identified in porcine stomach using a radioimmunoassay with conventional polyclonal antisera developed against a synthetic peptide analogue for progastrin processing intermediates, gastrin 6-G(Tyr-Gly-Trp-Met-Asp-Phe-Gly).	Glycine	10-17	gastrin	Rattus norvegicus	58-65
3596169-2	1987	We developed monoclonal antibodies specific for glycine-extended processing intermediates of progastrin (gastrin G).	Glycine	48-55	gastrin	Rattus norvegicus	96-103
3382697-5	1988	The high frequency and clustering of proline and glycine residues in estrogen receptor, progesterone receptor and glucose-6-phosphate dehydrogenase suggests that the translating ribosomes may slow down during synthesis of these proteins due to limiting levels of these tRNAs in E2-deprived uteri.	Glycine	49-56	glucose-6-phosphate dehydrogenase	Homo sapiens	114-147
11600567-5	2001	A greater reduction was seen when both L80 and L81 were substituted with glycine, and complete loss of affinity for IGF-I and IGF-II occurred when all three targeted amino acids were changed to glycine.	Glycine	194-201	insulin like growth factor 2	Homo sapiens	126-132
3138141-4	1988	These results suggest that, in the brain, milacemide is oxidized to glycine and that this reaction is mediated primarily by monoamine oxidase B.	Glycine	68-75	monoamine oxidase B	Homo sapiens	124-143
3571285-2	1987	T-protein, one of the components of the glycine cleavage system, catalyzes the synthesis of the H-protein-bound intermediate from methylenetetrahydrofolate, ammonia, and H-protein having a reduced lipoyl prosthetic group (Okamura-Ikeda, K., Fujiwara, K., and Motokawa, Y.	Glycine	40-47	myosin binding protein H	Homo sapiens	96-105
3571285-2	1987	T-protein, one of the components of the glycine cleavage system, catalyzes the synthesis of the H-protein-bound intermediate from methylenetetrahydrofolate, ammonia, and H-protein having a reduced lipoyl prosthetic group (Okamura-Ikeda, K., Fujiwara, K., and Motokawa, Y.	Glycine	40-47	myosin binding protein H	Homo sapiens	170-179
2451666-1	1988	D-Tyr-Gly-[Nle28,31,pNO2-Phe33)CCK-26-33).	Glycine	6-9	cholecystokinin	Rattus norvegicus	31-34
11516159-1	2001	The role of cytosolic and mitochondrial serine hydroxymethyltransferase in supplying one-carbon groups for purine and thymidylate biosynthesis in MCF-7 cells was investigated by observing folate-mediated one-carbon metabolism of l-[3-(13)C]serine, [2-(13)C]glycine, and [(13)C]formate.	Glycine	257-264	serine hydroxymethyltransferase 1	Homo sapiens	12-71
3280121-3	1988	Examining fractionated mononuclear cells from bone marrow or peripheral blood, an N-ras mutation at position 13 was observed in one patient with overt leukemia, resulting in a base change from GGT to TGT thus converting glycine to cysteine.	Glycine	220-227	NRAS proto-oncogene, GTPase	Homo sapiens	82-87
3346666-0	1988	Formation of the neurotransmitter glycine from the anticonvulsant milacemide is mediated by brain monoamine oxidase B.	Glycine	34-41	monoamine oxidase B	Homo sapiens	98-117
3576974-4	1987	Nucleic acid sequence analysis of the activated N-ras gene revealed a point mutation at codon 12 resulting in a glycine to aspartic acid substitution.	Glycine	112-119	neuroblastoma ras oncogene	Mus musculus	48-53
2882693-7	1987	DFP inhibited the activity of dipeptidyl peptidase IV in these vesicles and there was a direct correlation between the activity of the enzyme and the capacity of beta-casomorphin to inhibit Gly-Sar uptake.	Glycine	190-193	dipeptidyl peptidase 4	Oryctolagus cuniculus	30-53
11516159-6	2001	The cleavage of serine to glycine and 5,10-methylenetetrahydrofolate by cytosolic serine hydroxymethyltransferase does not appear to be a major source of one-carbon groups for either purine or thymidylate biosynthesis.	Glycine	26-33	serine hydroxymethyltransferase 1	Homo sapiens	72-113
11513726-8	2001	We show that mutation of this glycine to alanine in DAPP1 converts DAPP1 into a TAPP1-like PH domain that only interacts with PtdIns(3,4)P(2), whereas the alanine to glycine mutation in TAPP1 permits the TAPP1 PH domain to interact with PtdIns(3,4,5)P(3).	Glycine	30-37	pleckstrin homology domain containing A1	Homo sapiens	80-85
3348809-0	1988	Cloning of cDNA encoding human H-protein, a constituent of the glycine cleavage system.	Glycine	63-70	myosin binding protein H	Homo sapiens	31-40
3348809-1	1988	A cDNA that encodes human H-protein, a constituent protein of the glycine cleavage system, was cloned with anti-rat H-protein antibody as a probe from a human liver cDNA library constructed with an expression vector, lambda gt11.	Glycine	66-73	myosin binding protein H	Homo sapiens	26-35
11513726-8	2001	We show that mutation of this glycine to alanine in DAPP1 converts DAPP1 into a TAPP1-like PH domain that only interacts with PtdIns(3,4)P(2), whereas the alanine to glycine mutation in TAPP1 permits the TAPP1 PH domain to interact with PtdIns(3,4,5)P(3).	Glycine	30-37	pleckstrin homology domain containing A1	Homo sapiens	186-191
11513726-8	2001	We show that mutation of this glycine to alanine in DAPP1 converts DAPP1 into a TAPP1-like PH domain that only interacts with PtdIns(3,4)P(2), whereas the alanine to glycine mutation in TAPP1 permits the TAPP1 PH domain to interact with PtdIns(3,4,5)P(3).	Glycine	30-37	pleckstrin homology domain containing A1	Homo sapiens	186-191
3469204-2	1987	The peptide was designed to be triple helical and to contain the sequence Arg-Gly-Asp, which has been implicated as the cell attachment site of fibronectin, vitronectin, fibrinogen, and von Willebrand factor, and is also present in type I collagen.	Glycine	78-81	vitronectin	Homo sapiens	157-168
2449435-2	1988	Liposomes containing platelet glycoproteins IIb-IIIa complex have been shown to bind vitronectin-coated surfaces through an Arg-Gly-Asp cell attachment mechanism.	Glycine	128-131	vitronectin	Homo sapiens	85-96
11514359-11	2001	In addition, embryonic Lepr-L mRNA levels were higher in GT than in YL sows, and B(9) + glycine dietary supplement decreased the mRNA expression levels of Lep in backfat and of Lepr in embryonic tissues.	Glycine	88-95	leptin receptor	Sus scrofa	177-181
2449435-7	1988	A synthetic hexapeptide containing the Arg-Gly-Asp sequence inhibited vitronectin binding to platelets.	Glycine	43-46	vitronectin	Homo sapiens	70-81
11514359-13	2001	The effect of B(9) + glycine on Lepr-L mRNA expression levels was only seen in YL sows, whereas the treatment lowered Lepr-L expression levels in both endometrial and embryonic tissues.	Glycine	21-28	leptin receptor	Sus scrofa	32-36
2432397-4	1986	We found that the change from Thr to Ile at position 338 or the replacement of a fragment of c-src containing Gly-63, Arg-95, and Thr-96 with a corresponding fragment of v-src containing Asp-63, Trp-95, and Ile-96 converted p60c-src into a transforming protein by the criteria of focus formation, anchorage-independent growth, and tumor formation in newborn chickens.	Glycine	110-113	SRC proto-oncogene, non-receptor tyrosine kinase	Gallus gallus	93-98
11514359-15	2001	Moreover, the effects of B(9) + glycine on expression levels of embryonic and endometrial Lepr-L mRNA in YL sows may explain the previously reported effects of B(9) on embryo survival rate and litter size observed in occidental multiparous sows.	Glycine	32-39	leptin receptor	Sus scrofa	90-94
2432397-4	1986	We found that the change from Thr to Ile at position 338 or the replacement of a fragment of c-src containing Gly-63, Arg-95, and Thr-96 with a corresponding fragment of v-src containing Asp-63, Trp-95, and Ile-96 converted p60c-src into a transforming protein by the criteria of focus formation, anchorage-independent growth, and tumor formation in newborn chickens.	Glycine	110-113	SRC proto-oncogene, non-receptor tyrosine kinase	Gallus gallus	95-98
3422188-13	1988	These homologies further establish that GPIIb-IIIa from platelets, together with the vitronectin and the fibronectin receptors, are members of a supergene family of adhesion receptors with a recognition specificity for Arg-Gly-Asp amino acid sequences.	Glycine	223-226	integrin subunit alpha 2b	Homo sapiens	40-45
3422188-13	1988	These homologies further establish that GPIIb-IIIa from platelets, together with the vitronectin and the fibronectin receptors, are members of a supergene family of adhesion receptors with a recognition specificity for Arg-Gly-Asp amino acid sequences.	Glycine	223-226	vitronectin	Homo sapiens	85-96
3098173-0	1986	Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.	Glycine	17-24	complement C2	Bos taurus	57-60
11589724-15	2001	Pharmacological characterisation of the 287V --&gt; F CCK-B/gastrin receptor reveals wild-type affinities for G17 amide, glycine-extended gastrin, CCK-8S and L-365,260.	Glycine	121-128	gastrin	Homo sapiens	60-67
3098173-0	1986	Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.	Glycine	74-81	complement C2	Bos taurus	57-60
3098173-0	1986	Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.	Glycine	74-81	complement C2	Bos taurus	57-60
3098173-1	1986	Glycine is converted to carbon dioxide and an intermediate attached to a lipoic acid group on H-protein in the P-protein-catalyzed partial reaction of the glycine cleavage reaction [K. Fujiwara and Y. Motokawa (1983) J. Biol.	Glycine	0-7	OCA2 melanosomal transmembrane protein	Bos taurus	111-120
3098173-1	1986	Glycine is converted to carbon dioxide and an intermediate attached to a lipoic acid group on H-protein in the P-protein-catalyzed partial reaction of the glycine cleavage reaction [K. Fujiwara and Y. Motokawa (1983) J. Biol.	Glycine	155-162	OCA2 melanosomal transmembrane protein	Bos taurus	111-120
3098173-4	1986	The results presented in this paper indicate that the decarboxylation is not accompanied by the removal of a C-2 hydrogen atom of glycine and instead both C-2 hydrogens are transferred with the alpha carbon atom to the intermediate formed during the decarboxylation of glycine.	Glycine	269-276	complement C2	Bos taurus	155-158
2428041-8	1986	Vitronectin, another adhesion molecule that apparently binds to cells via a cell surface receptor that recognizes Arg-Gly-Asp sequences, also was capable of supporting trophoblast outgrowth.	Glycine	118-121	vitronectin	Mus musculus	0-11
2827651-1	1987	We synthesized a hexapeptide, Gly-His-His-Pro-His-Gly, previously identified as a tandem motif in the histidine-rich glycoprotein (HRG) which has multiple heme-binding sites.	Glycine	30-33	histidine rich glycoprotein	Homo sapiens	102-129
2827651-1	1987	We synthesized a hexapeptide, Gly-His-His-Pro-His-Gly, previously identified as a tandem motif in the histidine-rich glycoprotein (HRG) which has multiple heme-binding sites.	Glycine	30-33	histidine rich glycoprotein	Homo sapiens	131-134
3317405-4	1987	The 84-residue mature rat MGP predicted from the cDNA sequence has an additional 5 residues at its C terminus (-Arg-Arg-Gly-Ala-Lys) not seen in the sequence of MGP isolated from bovine bone.	Glycine	120-123	matrix Gla protein	Rattus norvegicus	26-29
11527579-2	2001	Allosteric activators such as D-glucose-6-phosphate and glycine increase the affinity of PEPC for its substrate PEP at pH 8.0 and pH 7.0.	Glycine	56-63	MLO-like protein 4	Zea mays	89-93
11509327-3	2001	TRX is a small, ubiquitous protein with two redox-active half-cysteine residues, -Cys-Gly-Pro-Cys, in its active center.	Glycine	86-89	thioredoxin	Homo sapiens	0-3
3038106-2	1987	Analysis using synthetic 20-mer oligonucleotide probes revealed a point mutation from G to C at the first letter of codon 13 of the N-ras gene resulting in the substitution of arginine for glycine.	Glycine	189-196	NRAS proto-oncogene, GTPase	Homo sapiens	132-137
3297170-1	1987	Enkephalinase B from rat brain membrane which hydrolyzes enkephalin at the Gly-Gly bond was purified about 9400-fold to apparent electrophoretic homogeneity.	Glycine	75-78	dipeptidylpeptidase 3	Rattus norvegicus	0-15
3297170-1	1987	Enkephalinase B from rat brain membrane which hydrolyzes enkephalin at the Gly-Gly bond was purified about 9400-fold to apparent electrophoretic homogeneity.	Glycine	79-82	dipeptidylpeptidase 3	Rattus norvegicus	0-15
3536894-4	1986	The complete prorenin sequence was then excised from the renatured hybrid protein using blood coagulation factor Xa, a proteinase which is highly specific for the tetrapeptide insert Ile-Glu-Gly-Arg introduced between the 9 amino-terminal residues of the trp E gene product and the first amino acid (Thr 1) of prorenin.	Glycine	191-194	coagulation factor X	Homo sapiens	106-115
3771096-2	1986	Since this derivative is stable in trifluoroacetic acid:CH2 Cl2 (1:1) and anhydrous hydrogen fluoride, Boc-Cys(Npys) could be used directly in solid phase synthesis of the 14-peptide acetyl-Cys(Npys)-Gly-Glu-Gln-Gln-His-His-Pro-Gly-Gly-Gly-Ala-Lys-G ln-Ala-amide.	Glycine	200-203	BOC cell adhesion associated, oncogene regulated	Homo sapiens	103-106
11500568-5	2001	These substitutions resulted in a strongly stimulated GSH accumulation in the transformed E. coli strain showing that these residues play a crucial role in the differential recognition of beta-alanine and glycine by hGSHS.	Glycine	205-212	glutathione synthetase	Homo sapiens	216-221
3755137-0	1986	Protein and cDNA sequence of a glycine-rich, dimethylarginine-containing region located near the carboxyl-terminal end of nucleolin (C23 and 100 kDa).	Glycine	31-38	nucleolin	Cricetulus griseus	122-131
3755137-1	1986	By a combination of protein chemistry and recombinant DNA methods a glycine-rich region was found to be located near the carboxyl terminus of the nucleolar specific phosphoprotein, nucleolin, from Novikoff hepatoma (protein C23) and Chinese hamster ovary cells (100-kDa nucleolar protein).	Glycine	68-75	nucleolin	Cricetulus griseus	181-190
3009860-1	1986	We have constructed two point mutants of Rous sarcoma virus in which the amino-terminal glycine residue of the transforming protein, p60src, was changed to an alanine or a glutamic acid residue.	Glycine	88-95	p60 src	Rous sarcoma virus	133-139
3486674-2	1986	Studies with synthetic peptides have shown that the active site of this anaphylatoxin resides in the COOH-terminal portion of C3a; the minimal peptide structure capable of expressing activity contains residues 73-77, Leu-Gly-Leu-Ala-Arg (C3a-73-77).	Glycine	221-224	complement C3	Homo sapiens	126-129
3004917-4	1986	When the relative quantities of alpha-amidated and COOH-terminally glycine-extended forms of alpha MSH were assessed in biosynthetic labeling experiments, it was shown that either L-ascorbate or an epimer of the vitamin, D-isoascorbate, was capable of supporting cellular alpha-amidation.	Glycine	67-74	proopiomelanocortin	Rattus norvegicus	93-102
3314270-1	1987	It has been demonstrated that A-chain of insulin in the salmon O. keta consists of 21 amino acid residues with N-terminal glycine and C-terminal asparagine.	Glycine	122-129	insulin	Canis lupus familiaris	41-48
3102381-7	1987	Treatment of ConAS with glycine-hydrochloride buffer (pH 2) resulted in a total loss of antiviral activity mediated by gamma interferon (IFN-gamma).	Glycine	24-45	interferon gamma	Bos taurus	137-146
3818601-3	1987	At the amino acid level, this mutation results in the substitution of an aspartic acid residue for a conserved glycine at position 231 of cytochrome b.	Glycine	111-118	mitochondrially encoded cytochrome b	Homo sapiens	138-150
3826354-5	1987	Microsequence analysis showed that the amino terminal primary sequence of this small CCK was Gly-Trp-Met-Asp.	Glycine	93-96	cholecystokinin	Canis lupus familiaris	85-88
3305626-3	1987	PRG (38.9 kDa) contains 40% carbohydrate consisting of 6 triantennary N-linked units and a single peptide chain of 231 amino acids, 75% of which = PRO + GLY + GLN.	Glycine	153-156	proline rich protein BstNI subfamily 3	Homo sapiens	0-3
3009377-1	1986	Activated c-Ki-ras with a point mutation (GGT to CGT) at codon 12, resulting in the substitution of arginine for glycine, was found in DNA from metastatic pancreatic adenocarcinoma in a lymph node.	Glycine	113-120	KRAS proto-oncogene, GTPase	Homo sapiens	10-18
11375993-6	2001	Only the N-terminal Gly-Leu cleavage site is conserved in rat OPN (Gly151-Leu152).	Glycine	20-23	secreted phosphoprotein 1	Homo sapiens	62-65
3009377-1	1986	Activated c-Ki-ras with a point mutation (GGT to CGT) at codon 12, resulting in the substitution of arginine for glycine, was found in DNA from metastatic pancreatic adenocarcinoma in a lymph node.	Glycine	113-120	UDP glycosyltransferase 8	Homo sapiens	49-52
3951985-3	1986	A gastric carcinoma was found to possess a single mutated Ki-ras allele (gly-12 to ser), as well as a 30-50 fold amplified normal allele.	Glycine	73-76	KRAS proto-oncogene, GTPase	Homo sapiens	58-64
3790720-4	1987	An adenine to guanine transition in the first nucleotide of exon d causes the substitution of a glycine codon (GGT) for the normal aspartic acid codon (GAT).	Glycine	96-103	glycine-N-acyltransferase	Homo sapiens	152-155
11437383-0	2001	Glycine-extended gastrin promotes the invasiveness of human colon cancer cells.	Glycine	0-7	gastrin	Homo sapiens	17-24
3794976-8	1986	The response of mature jejunum and ileum following systemic gastrin infusion was a mild to moderate rise in galactose and glycine absorption, although statistical significance was not achieved.	Glycine	122-129	gastrin	Rattus norvegicus	60-67
3794976-9	1986	However, following luminal gastrin infusion into mature small intestine segments, there was a 4.54 fold rise in galactose absorption (P less than .01) and a 4.79 fold rise in glycine absorption (P less than .01) when compared with controls.	Glycine	175-182	gastrin	Rattus norvegicus	27-34
3016513-1	1985	p60src of wild-type Rous sarcoma virus is myristylated at its N-terminal glycine residue.	Glycine	73-80	p60 src	Rous sarcoma virus	0-6
3840230-9	1985	Each of these regions contains the presumed active site sequence Trp-Cys-Gly-His-Cys-Lys, suggesting that PDI, similar in action to thioredoxin, catalyses disulphide bond interchange via an internal disulphide-sulphydryl interchange.	Glycine	73-76	prolyl 4-hydroxylase subunit beta	Rattus norvegicus	106-109
3897758-4	1985	However, the cleavage pattern differed markedly from one CCK peptide to another: in the penta- and hexapeptide of CCK the bonds hydrolyzed were either Asp-Phe and Trp-Met or, Asp-Phe and Gly-Trp, respectively.	Glycine	187-190	cholecystokinin	Rattus norvegicus	114-117
3877728-10	1985	The unique N-terminal amino acid sequences of both forms of CSF were the same: (Lys-Glu-Val-Ser-Glu-His-X-Ser-His-Met-Ile-Gly-Asn).	Glycine	122-125	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	60-63
11437383-1	2001	Colorectal cancers express significant amounts of immature glycine-extended gastrin (G-Gly) and G-Gly is able to stimulate cell proliferation in colonic cell lines and mucosa.	Glycine	59-66	gastrin	Homo sapiens	76-83
11399059-9	2001	The IEC adhesion to FN was inhibited by specific antibody against the FN receptor (VLA-5), as well as competitive Arg-Gly-Asp (RGD) peptide.	Glycine	118-121	fibronectin 1	Mus musculus	20-22
2414098-7	1985	An Arg-Gly-Asp sequence, which has previously been shown to be the cell attachment site in fibronectin, was found in vitronectin immediately after the NH2-terminal somatomedin B sequence.	Glycine	7-10	vitronectin	Homo sapiens	117-128
2414098-9	1985	The Arg-Gly-Asp sequence appears to constitute the cell attachment site of vitronectin, since it is in the region where we have previously localized the cell attachment site, its presence correlate with cell attachment activity among the insert-coded polypeptides, and because previous results have shown that synthetic peptides containing the Arg-Gly-Asp sequence inhibit the cell attachment function of vitronectin.	Glycine	8-11	vitronectin	Homo sapiens	75-86
2414098-9	1985	The Arg-Gly-Asp sequence appears to constitute the cell attachment site of vitronectin, since it is in the region where we have previously localized the cell attachment site, its presence correlate with cell attachment activity among the insert-coded polypeptides, and because previous results have shown that synthetic peptides containing the Arg-Gly-Asp sequence inhibit the cell attachment function of vitronectin.	Glycine	8-11	vitronectin	Homo sapiens	405-416
3897758-6	1985	The major bonds cleaved were Asp-Phe, Trp-Met and Gly-Trp for unsulfated CCK-8, whilst for the sulfated octapeptide, the Trp-Met bond became a minor cleavage site.	Glycine	50-53	cholecystokinin	Rattus norvegicus	73-76
11397844-6	2001	Migration stimulation by IGFBP-1 was abrogated by pretreatment with a Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP), but not a Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) hexapeptide, and by mutation of the RGD domain of IGFBP-1 to Trp-Gly-Asp (WGD).	Glycine	78-81	insulin like growth factor binding protein 1	Homo sapiens	25-32
2859127-5	1985	Since the inhibitory effects of Cys on both the decrease in the ratio of GSH/GSSG and the induction of ODC activity by TPA were greatly reduced by the inhibitors of gamma-glutamyl transpeptidase and gamma-glutamylcysteine synthetase, it is suggested that some of the inhibitory effects of Glu, Cys and Gly on tumor promotion could result from their interference with the metabolism of the tripeptide GSH, a natural antioxidant which inhibits chemical carcinogenesis.	Glycine	302-305	ornithine decarboxylase, structural 1	Mus musculus	103-106
2412224-0	1985	A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.	Glycine	89-96	vitronectin	Homo sapiens	49-60
11397844-6	2001	Migration stimulation by IGFBP-1 was abrogated by pretreatment with a Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP), but not a Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) hexapeptide, and by mutation of the RGD domain of IGFBP-1 to Trp-Gly-Asp (WGD).	Glycine	78-81	insulin like growth factor binding protein 1	Homo sapiens	197-204
11397844-6	2001	Migration stimulation by IGFBP-1 was abrogated by pretreatment with a Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP), but not a Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) hexapeptide, and by mutation of the RGD domain of IGFBP-1 to Trp-Gly-Asp (WGD).	Glycine	78-81	insulin like growth factor binding protein 1	Homo sapiens	25-32
3986189-4	1985	This peptide is 29 mol % histidine, 37% proline, and 16% glycine, indicating that most of these three amino acids are located in one region of HRG.	Glycine	57-64	histidine rich glycoprotein	Homo sapiens	143-146
11397844-6	2001	Migration stimulation by IGFBP-1 was abrogated by pretreatment with a Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP), but not a Gly-Arg-Gly-Glu-Ser-Pro (GRGESP) hexapeptide, and by mutation of the RGD domain of IGFBP-1 to Trp-Gly-Asp (WGD).	Glycine	78-81	insulin like growth factor binding protein 1	Homo sapiens	197-204
2999729-7	1985	Therefore, the structure of CCK due to the D conformation of Gly is more capable of interacting with brain CCK receptors.	Glycine	61-64	cholecystokinin	Cavia porcellus	28-31
11348627-0	2001	C-Terminal glycine is crucial for hyperalgesic activity of nociceptin/orphanin FQ-(1-6).	Glycine	11-18	prepronociceptin	Rattus norvegicus	59-69
2999729-7	1985	Therefore, the structure of CCK due to the D conformation of Gly is more capable of interacting with brain CCK receptors.	Glycine	61-64	cholecystokinin	Cavia porcellus	107-110
2991884-1	1985	p60src, the transforming protein kinase of Rous sarcoma virus, contains the 14-carbon saturated fatty acid, myristic acid, linked through an amide bond to the alpha-amino group of its NH2-terminal glycine residue.	Glycine	197-204	p60 src	Rous sarcoma virus	0-6
2981091-2	1985	The EBNA protein contains a unique glycine-alanine repeating sequence.	Glycine	35-42	EBNA	Human gammaherpesvirus 4	4-8
3885009-6	1985	The rad3-1 mutation changed a glutamic acid to lysine, and the rad3-2 mutation changed a glycine to arginine.	Glycine	89-96	TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3	Saccharomyces cerevisiae S288C	63-67
11348627-0	2001	C-Terminal glycine is crucial for hyperalgesic activity of nociceptin/orphanin FQ-(1-6).	Glycine	11-18	prepronociceptin	Rattus norvegicus	70-81
11348627-2	2001	Replacement of the C-terminal glycine by L-alanine (Phe-Gly-Gly-Phe-Thr-Ala) in orphanin FQ/nociceptin-(1-6) abolished the hyperalgesic potency of native orphanin FQ/nociceptin-(1-6) (Phe-Gly-Gly-Phe-Thr-Gly), but analgesic activity was retained and was diminished by naloxone.	Glycine	30-37	prepronociceptin	Rattus norvegicus	80-91
4010269-12	1985	More importantly, to our knowledge, this is the first demonstration that exogenously administered gastrin can increase absorption of carbohydrate (galactose; P less than 0.01) and protein (glycine; P less than 0.05).	Glycine	189-196	gastrin	Rattus norvegicus	98-105
11348627-2	2001	Replacement of the C-terminal glycine by L-alanine (Phe-Gly-Gly-Phe-Thr-Ala) in orphanin FQ/nociceptin-(1-6) abolished the hyperalgesic potency of native orphanin FQ/nociceptin-(1-6) (Phe-Gly-Gly-Phe-Thr-Gly), but analgesic activity was retained and was diminished by naloxone.	Glycine	30-37	prepronociceptin	Rattus norvegicus	92-102
11348627-2	2001	Replacement of the C-terminal glycine by L-alanine (Phe-Gly-Gly-Phe-Thr-Ala) in orphanin FQ/nociceptin-(1-6) abolished the hyperalgesic potency of native orphanin FQ/nociceptin-(1-6) (Phe-Gly-Gly-Phe-Thr-Gly), but analgesic activity was retained and was diminished by naloxone.	Glycine	30-37	prepronociceptin	Rattus norvegicus	154-165
6207529-4	1984	hGRP is flanked at its carboxyl terminus by two basic amino acids, following a glycine used for amidation of the carboxyl-terminal methionine.	Glycine	79-86	gastrin releasing peptide	Homo sapiens	0-4
11348627-2	2001	Replacement of the C-terminal glycine by L-alanine (Phe-Gly-Gly-Phe-Thr-Ala) in orphanin FQ/nociceptin-(1-6) abolished the hyperalgesic potency of native orphanin FQ/nociceptin-(1-6) (Phe-Gly-Gly-Phe-Thr-Gly), but analgesic activity was retained and was diminished by naloxone.	Glycine	30-37	prepronociceptin	Rattus norvegicus	166-176
11348627-3	2001	Removal of the C-terminal amino acid (glycine or alanine) from orphanin FQ/nociceptin-(1-6) caused a significant loss of analgesic activity.	Glycine	38-45	prepronociceptin	Rattus norvegicus	63-74
6644098-2	1983	Incubation of isolated epidermal cells with mM concentrations of glycine, asparagine, glutamic acid, canavanine, arginine, and/or lysine inhibited dramatically the induction of ornithine decarboxylase activity by the tumor promoter.	Glycine	65-72	ornithine decarboxylase, structural 1	Mus musculus	177-200
6150137-6	1984	Elastin is composed largely of glycine, proline, and other hydrophobic residues and contains multiple lysine-derived cross-links, such as the desmosines, which link the individual polypeptide chains into a rubber-like network.	Glycine	31-38	elastin	Homo sapiens	0-7
11348627-3	2001	Removal of the C-terminal amino acid (glycine or alanine) from orphanin FQ/nociceptin-(1-6) caused a significant loss of analgesic activity.	Glycine	38-45	prepronociceptin	Rattus norvegicus	75-85
6466675-1	1984	Extraction of spectrin-depleted erythrocyte membranes with the non-ionic detergent Tween 20, in a 0.1 M glycine-NaOH buffer (pH 9.8) leads to the solubilization of band 4.1 and the sialoglycoproteins.	Glycine	104-111	erythrocyte membrane protein band 4.1	Homo sapiens	164-172
11348627-4	2001	It is anticipated that glycine plays a crucial role in the biphasic activity of orphanin FQ/nociceptin-(1-6).	Glycine	23-30	prepronociceptin	Rattus norvegicus	80-91
11348627-4	2001	It is anticipated that glycine plays a crucial role in the biphasic activity of orphanin FQ/nociceptin-(1-6).	Glycine	23-30	prepronociceptin	Rattus norvegicus	92-102
6469978-2	1984	Glycine is converted to carbon dioxide and an intermediate attached to H-protein in the P-protein-catalyzed partial reaction of the glycine cleavage reaction (Fujiwara, K., and Motokawa, Y.	Glycine	0-7	myosin binding protein H	Homo sapiens	71-80
11301188-7	2001	Determination of cytokine mRNA in the course of Fas-mediated apoptosis in the presence of Tf or Tf-Gly showed upregulation of mRNA for Fas ligand and TNF-alpha in CD56(+) and downregulation of these transcripts along with upregulation of mRNA for interleukin-10 in CD3(+) marrow cells.	Glycine	99-102	neural cell adhesion molecule 1	Homo sapiens	163-167
6469978-2	1984	Glycine is converted to carbon dioxide and an intermediate attached to H-protein in the P-protein-catalyzed partial reaction of the glycine cleavage reaction (Fujiwara, K., and Motokawa, Y.	Glycine	132-139	myosin binding protein H	Homo sapiens	71-80
11401448-4	2001	CNRc1 and c2 lack the Arg-Gly-Asp (RGD) sequence that is conserved in the EC1 of CNR1-8, which is necessary for binding to Reelin.	Glycine	26-29	protocadherin alpha subfamily C, 1	Mus musculus	0-5
20488055-1	1984	N-Tyr-MIF-1 (Tyr-Pro-Leu-Gly.NH(2)), an immunoreactive neuropeptide exhibiting saturable high affinity binding in rat brain was found to be converted into MIF-1 (Pro-Leu-Gly.NH(2)) by a specific brain aminopeptidase present in rat brain homogenates or cytosol, but with low activity associated with synaptosomal plasma membranes and microsomes.	Glycine	25-28	predicted gene 4924	Mus musculus	6-11
6133861-0	1983	Effects of bile acids and their glycine conjugates on gamma-glutamyl transpeptidase.	Glycine	32-39	inactive glutathione hydrolase 2	Homo sapiens	54-83
6133861-1	1983	Glycine and taurine conjugates of bile acids modulate gamma-glutamyl transpeptidase by interacting with the cysteinylglycine binding site (acceptor site) of the enzyme.	Glycine	0-7	inactive glutathione hydrolase 2	Homo sapiens	54-83
11152972-7	2001	Mutations of K-ras, analyzed by single-strand conformation polymorphism and sequencing, were, in codon 12, wild type GGT (glycine), to GAT (aspartic acid); to GTT (valine); and to CGT (arginine); and in codon 61, wild-type CAA (glutamine), to CGA (arginine).	Glycine	122-129	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	13-18
6664934-1	1983	Intracerebroventricular injection of glycine elevated the level and synthesis rate of acetylcholine and the activity of choline acetyltransferase in the striatum.	Glycine	37-44	choline O-acetyltransferase	Rattus norvegicus	120-145
7153213-1	1982	Glycine decarboxylase, tentatively called P-protein, was inactivated when it was incubated with glycine in the presence of the aminomethyl carrier protein, called H-protein.	Glycine	96-103	myosin binding protein H	Homo sapiens	163-172
20488055-1	1984	N-Tyr-MIF-1 (Tyr-Pro-Leu-Gly.NH(2)), an immunoreactive neuropeptide exhibiting saturable high affinity binding in rat brain was found to be converted into MIF-1 (Pro-Leu-Gly.NH(2)) by a specific brain aminopeptidase present in rat brain homogenates or cytosol, but with low activity associated with synaptosomal plasma membranes and microsomes.	Glycine	25-28	predicted gene 4924	Mus musculus	155-160
6318112-2	1983	Molecular characterization of one of the genes revealed that the twelfth codon was GAA instead of GGA of the normal allele, encoding glutamic acid in place of glycine.	Glycine	159-166	alpha glucosidase	Rattus norvegicus	83-86
11123201-6	2001	Thus the equipotent actions of secretin and secretin-Gly on pancreatic secretion appear to result from equal binding and activation of the pancreatic secretin receptor.	Glycine	53-56	secretin receptor	Rattus norvegicus	150-167
6287457-7	1982	We conclude that the activity responsible for processing poliovirus polypeptides at Gln-Gly pairs resides in the primary structure of P3-7c (or P3-2 and P3-6a) and not in P2-X.	Glycine	88-91	CD8a molecule	Homo sapiens	144-148
6627099-4	1983	LCAT was found to have a relatively high content of glutamic acid, aspartic acid, glycine, and leucine residues and four half-cystines.	Glycine	82-89	lecithin-cholesterol acyltransferase	Homo sapiens	0-4
12083956-10	2001	The coregulatory proteins ARA70 and ARA160 differentially affected the activity of the mutated AR Glu(231)--&gt;Gly, which was discovered in a mouse authochthonous prostate tumor.	Glycine	112-115	TATA element modulatory factor 1	Homo sapiens	36-42
6275900-7	1982	A peptide containing the amino acid sequence of histone H2b from Gly-26 to Lys-34 (Gly-Lys-Lys-Arg-Lys-Arg-Ser-Arg-Lys-Ala) was synthesized.	Glycine	65-68	cuticle collagen 13	Bos taurus	48-59
11478419-3	2001	Due to the important implications of the dopamine D3 receptor gene (DRD3) in motor control, we investigated the frequency of polymorphic serine (ser) to glycine (gly) substitution of the gene DRD3 in Chinese schizophrenic patients.	Glycine	153-160	dopamine receptor D3	Homo sapiens	192-196
6687626-7	1983	As is the case for the bovine arginine-vasopressin-neurophysin II (AVP-NpII) precursor, the signal sequence of the OT-NpI precursor is immediately followed by the nonapeptide hormone which is connected to neurophysin I by a Gly-Lys-Arg sequence.	Glycine	224-227	arginine vasopressin	Bos taurus	30-65
6687626-7	1983	As is the case for the bovine arginine-vasopressin-neurophysin II (AVP-NpII) precursor, the signal sequence of the OT-NpI precursor is immediately followed by the nonapeptide hormone which is connected to neurophysin I by a Gly-Lys-Arg sequence.	Glycine	224-227	arginine vasopressin	Bos taurus	67-75
7167416-3	1982	Glycine elevated the choline acetyltransferase activity in the striatum, but did not affect acetylcholine esterase.	Glycine	0-7	choline O-acetyltransferase	Rattus norvegicus	21-46
11478419-3	2001	Due to the important implications of the dopamine D3 receptor gene (DRD3) in motor control, we investigated the frequency of polymorphic serine (ser) to glycine (gly) substitution of the gene DRD3 in Chinese schizophrenic patients.	Glycine	153-156	dopamine receptor D3	Homo sapiens	68-72
6857231-3	1983	N-terminal amino acid residues of Gp1 are glycine and alanine, and that of Gp2 is glycine.	Glycine	42-49	GTP binding protein 1	Homo sapiens	34-37
11478419-3	2001	Due to the important implications of the dopamine D3 receptor gene (DRD3) in motor control, we investigated the frequency of polymorphic serine (ser) to glycine (gly) substitution of the gene DRD3 in Chinese schizophrenic patients.	Glycine	153-156	dopamine receptor D3	Homo sapiens	192-196
6790577-3	1981	The activities of glycine decarboxylase (P-protein) and the aminomethyl carrier protein (H-protein), two of the four protein components of the glycine cleavage system, were considerably reduced in both the liver and brain; the extent of reduction was greater in the H-protein.	Glycine	18-25	myosin binding protein H	Homo sapiens	266-275
6790577-8	1981	Partial inactivation of P-protein could result secondarily from impaired metabolism of glycine resulting from deficiency in the activity of H-protein.	Glycine	87-94	myosin binding protein H	Homo sapiens	140-149
6276766-1	1982	The sequence of a cDNA encoding the nonapeptide arginine vasopressin (AVP) and its carrier protein, neurophysin II (NpII) from bovine hypothalamus, proves that the 166-amino acid precursor molecule contains a signal peptide of 19 amino acids followed directly by AVP connected to NpII by a Gly-Lys-Arg sequence.	Glycine	290-293	arginine vasopressin	Bos taurus	100-114
10998097-6	2000	When rho1(T314A/L317A) subunits were coexpressed with GABA gamma2S, glycine alpha1 or glycine alpha2 subunits, suppression by GABA of spontaneously active current was reduced compared to that of homomeric rho1(T314A/L317A) receptors.	Glycine	86-93	MGC75582, possible similarity to act2 S homeolog	Xenopus laevis	94-100
6276766-1	1982	The sequence of a cDNA encoding the nonapeptide arginine vasopressin (AVP) and its carrier protein, neurophysin II (NpII) from bovine hypothalamus, proves that the 166-amino acid precursor molecule contains a signal peptide of 19 amino acids followed directly by AVP connected to NpII by a Gly-Lys-Arg sequence.	Glycine	290-293	arginine vasopressin	Bos taurus	116-120
6789499-4	1980	The hemoglobin fraction eluted with the second eluant was applied onto a DEAE-cellulose column and eluted with 0.2 M glycine containing 0.01 percent KCN, resulting in complete isolation of CA-C at high recovery rate.	Glycine	117-124	carbonic anhydrase 2	Homo sapiens	189-193
6968751-3	1980	The porcine C3a octapeptide is 3 times more active than the common pentapeptide, but the human octapeptide (Ala(70)-Ser-His-Leu(73)-Gly-Leu(75)-Ala-Arg(77) is 12 times more active than the pentapeptide.	Glycine	132-135	complement C3	Homo sapiens	12-15
6934068-1	1980	An auxotrophic mutant, GAT-, derived from the Chinese hamster cell line CHO-K1 and exhibiting multiple growth requirements for glycine, adenine, and thymidine, has been shown to be deficient in one of the folate-dependent enzymes, folylpolyglutamate synthetase (FPGS).	Glycine	127-134	glycine-N-acyltransferase	Homo sapiens	23-26
6444384-0	1980	The proteolipid of a mutant ATPase from Escherichia coli defective in H+-conduction contains a glycine instead of the carbodiimide-reactive aspartyl residue.	Glycine	95-102	ATPase	Escherichia coli	28-34
7349457-1	1980	3 p. 100 of Maillard"s reaction products (MRP), obtained by mild heating of glucose and glycine, were added to a semi-synthetic diet sterilized by irradiation.	Glycine	88-95	ATP binding cassette subfamily C member 2	Rattus norvegicus	42-45
34597-2	1979	The uptakes of glycine and leucine were specificially inhibited by Me-AIB and b-BCH, respectively.	Glycine	15-22	ANIB1	Homo sapiens	70-73
6790577-9	1981	However, the H-protein from the patient could stimulate the P-protein catalyzed exchange of the carboxyl carbon of glycine with 14CO2, although the specific activity of the purified H-protein from the patient was only 4% of that of control human H-protein.	Glycine	115-122	myosin binding protein H	Homo sapiens	13-22
6790577-9	1981	However, the H-protein from the patient could stimulate the P-protein catalyzed exchange of the carboxyl carbon of glycine with 14CO2, although the specific activity of the purified H-protein from the patient was only 4% of that of control human H-protein.	Glycine	115-122	myosin binding protein H	Homo sapiens	182-191
6790577-9	1981	However, the H-protein from the patient could stimulate the P-protein catalyzed exchange of the carboxyl carbon of glycine with 14CO2, although the specific activity of the purified H-protein from the patient was only 4% of that of control human H-protein.	Glycine	115-122	myosin binding protein H	Homo sapiens	182-191
6109281-1	1980	When RBL-1 cells were incubated with L-cysteine (7.5 mM) and the ionophore A23187, the slow reacting substances SRS-GSH and SRS-Cys-Gly were formed.	Glycine	132-135	RB transcriptional corepressor like 1	Rattus norvegicus	5-10
7370278-5	1980	Thrombin and Factor Xa may possess a hydrophobic region near the P2 binding site which is unfavourable for either asparagine or D-alanine but which readily accommodates glycine, L-alanine or L-phenylalanine.	Glycine	169-176	coagulation factor II, thrombin	Bos taurus	0-8
500370-0	1979	Hemoglobin Bougardirey-Mali beta 119 (GH2) Gly replaced by Val.	Glycine	43-46	growth hormone 2	Homo sapiens	38-41
658785-5	1978	In stage II, remaining factor Xa is determined with the chromogenic substrate Bz-Ile-Glu-Gly-Arg-pNA.	Glycine	89-92	coagulation factor X	Homo sapiens	23-32
265581-4	1977	Lysine 119, the amino terminus of this peptide, which is derived from the histone 2A portion of protein A24, is linked by an isopeptide bond to the carboxyl group of a glycine residue.	Glycine	168-175	immunoglobulin kappa variable 2-23 (pseudogene)	Homo sapiens	104-107
11828-0	1976	Hemoglobin Fannin-Lubbock [alpha2 beta 2 119 (GH2) Gly replaced by Asp].	Glycine	51-54	growth hormone 2	Homo sapiens	46-49
11829-0	1976	Hemoglobin Fannin-Lubbock [alpha 2 beta 2 119(GH2) Gly replaced by Asp].	Glycine	51-54	growth hormone 2	Homo sapiens	46-49
1260137-0	1976	Hemoglobin pyrgos alpha2 beta2 83 (EF7) Gly leads to Asp: a new hemoglobin variant in double heterozygosity with hemoglobin S. An electrophoretically fast-moving hemoglobin variant was found to be present together with hemoglobin S, in the hemolysate of the rythrocytes of at 3-yr-old Greek boy.	Glycine	40-43	FAM3 metabolism regulating signaling molecule D	Homo sapiens	35-38
1260137-6	1976	Structural analysis of the variant hemoglobin revealed substitution of an aspartic acid for the glycine residue at the beta83 (EF7) position.	Glycine	96-103	FAM3 metabolism regulating signaling molecule D	Homo sapiens	127-130
970031-4	1976	The analysis of the isoaccepting tRNA by reversed-phase chromatography (RPC-5 system) showed the presence of 5 fractions for glycine and leucine, 3 for tyrosine, alanine and valine, 2 for arginine and 1 for phenylalanine.	Glycine	125-132	RNA polymerase III subunit E	Homo sapiens	72-77
1123347-1	1975	The structure of rat proalbumin, a liver precursor to rat serum albumin, has been determined to consist of the hexapeptide Arg-Gly-Val-Phe-Arg-Arg attached to the NH2 terminus of the polypeptide chain of rat serum albumin.	Glycine	127-130	albumin	Rattus norvegicus	24-31
1123347-1	1975	The structure of rat proalbumin, a liver precursor to rat serum albumin, has been determined to consist of the hexapeptide Arg-Gly-Val-Phe-Arg-Arg attached to the NH2 terminus of the polypeptide chain of rat serum albumin.	Glycine	127-130	albumin	Rattus norvegicus	64-71
5713454-5	1968	In the presence of an equimolar amount of each of the amino acids under consideration, the Ca(II)-DPA chelate forms mixed ligand (ternary) chelate yielding the following stepwise stability constants: log K(1) = 4.17 +/- 0.01, log K(2) = 0.78 +/- 0.01 for cysteine, log K(1) = 4.06 +/- 0.01, log K(2) = 0.65 +/- 0.01 for alanine, and log K(1) = 4.30 +/- 0.02, log K(2) = 0.11 +/- 0.01 for glycine.	Glycine	388-395	carbonic anhydrase 2	Homo sapiens	91-96
5971784-1	1966	Reinvestigation of the amino acid sequence of bovine chymotrypsinogen A suggests that the amino acid sequence at the N-terminus of the B-chain (residues 16-19) is -Ile-Val-Asn-Gly- rather than -Ile-Val-Gly-Asp- and that Ser-215 should be deleted.	Glycine	176-179	chymotrypsinogen A	Bos taurus	53-71
5971784-1	1966	Reinvestigation of the amino acid sequence of bovine chymotrypsinogen A suggests that the amino acid sequence at the N-terminus of the B-chain (residues 16-19) is -Ile-Val-Asn-Gly- rather than -Ile-Val-Gly-Asp- and that Ser-215 should be deleted.	Glycine	202-205	chymotrypsinogen A	Bos taurus	53-71
14797761-0	1950	Action of vitamin B12 in counteracting glycine toxicity in the chick.	Glycine	39-46	Major histocompatibility complex class I antigen BF2	Gallus gallus	18-21
18147155-0	1949	The distribution in rat tissues of the methylene carbonatom of glycine labeled with C14.	Glycine	63-70	anti-Mullerian hormone receptor type 2	Rattus norvegicus	84-87
33980825-5	2021	The NCL alarmin activity resides in its glycine/arginine-rich (GAR/RGG) motif and can be displayed by synthetic GAR/RGG peptides.	Glycine	40-47	nucleolin	Mus musculus	4-7
33931009-7	2021	Based on the observed subcellular localizations of chimeric GAREM1 and GAREM2 proteins, a glycine-rich region, which is present only in GAREM2, is required for the observed granule formation.	Glycine	90-97	GRB2 associated regulator of MAPK1 subtype 1	Rattus norvegicus	60-66
33522570-5	2021	Phenylalanine-to-serine substitutions of the phenylalanine:glycine repeats in the fibrillarin LC domain impede its phase transition into liquid-like droplets, as well as the hydrogel-like state composed of polymers, and also its incorporation into hydrogel or liquid-like droplets composed of wild-type LC domains.	Glycine	59-66	fibrillarin	Homo sapiens	82-93
33615395-8	2021	The activities of SOD and catalase (CAT) were significantly increased in the groups of 0.30 mg/kg NS-Gly diet (P < 0.05).	Glycine	101-104	catalase	Gallus gallus	26-34
33615395-8	2021	The activities of SOD and catalase (CAT) were significantly increased in the groups of 0.30 mg/kg NS-Gly diet (P < 0.05).	Glycine	101-104	catalase	Gallus gallus	36-39
33615395-12	2021	The mRNA levels of solute carrier family 3 member 1 (rBAT), solute carrier family 6 member 19 (B0AT1), and solute carrier family 15 member 1 (PepT1) increased at different degrees in the duodenum, especially in 0.15 and 0.60 mg/kg NS-Gly groups (P < 0.05).	Glycine	234-237	solute carrier family 15 member 1	Gallus gallus	142-147
33615395-13	2021	In the jejunum, the expression of B0AT1 was similar to that in the duodenum, and the expression of rBAT increased significantly in the 0.30 and 0.45 mg/kg NS-Gly groups (P < 0.05).	Glycine	158-161	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	99-103
33351193-2	2021	The rs2071307 genomic polymorphism, resulting in the substitution of a serine for a glycine residue in a VPG motif in tropoelastin, has an unusually high minor allele frequency in humans.	Glycine	84-91	elastin	Homo sapiens	118-130
33273058-6	2021	Payload release studies demonstrated that two camptothecins, CPT1 and the corresponding glycine analog (CPT2) were released from a cAC10 ADC by tumor cells.	Glycine	88-95	carnitine palmitoyltransferase 2	Rattus norvegicus	104-108
33601878-3	2021	In each module, genes with the most connectivity were selected as hub genes, including G antigen 12J (GAGE12J) in blue, proline, histidine and glycine rich 1 (PHGR1) in dark orange, DNA polymerase gamma 2, accessory subunit (POLG2) in dark red and collagen type XXI alpha 1 chain (COL21A1) in dark violet.	Glycine	143-150	ELAV like RNA binding protein 2	Homo sapiens	66-69
33601878-3	2021	In each module, genes with the most connectivity were selected as hub genes, including G antigen 12J (GAGE12J) in blue, proline, histidine and glycine rich 1 (PHGR1) in dark orange, DNA polymerase gamma 2, accessory subunit (POLG2) in dark red and collagen type XXI alpha 1 chain (COL21A1) in dark violet.	Glycine	143-150	proline, histidine and glycine rich 1	Homo sapiens	159-164
32986951-2	2021	Two of the most frequent oncogenic KRAS mutations observed in patients result in glycine to aspartic acid substitution at either codon 12 (G12D) or 13 (G13D).	Glycine	81-88	KRAS proto-oncogene, GTPase	Homo sapiens	35-39
681080-1	1978	Recently Gly-(Pro)3 a proline-rich protein (PRP) containing repetitive Gly-(Pro)3 or Gly-(Pro)4 sequences was isolated from human parotid saliva.	Glycine	9-12	pyrroline-5-carboxylate reductase 1	Homo sapiens	22-81
738857-6	1978	The incorporation of C14 glycine into skin collagen and the free glycine content of skins were also decreased.	Glycine	25-32	anti-Mullerian hormone receptor type 2	Rattus norvegicus	21-24
201250-0	1977	A glycine to serine substitution identifies the CYP 3 locus as the structural gene of iso 2 cytochrome c in Saccharomyces cerevisiae.	Glycine	2-9	peptidylprolyl isomerase CPR3	Saccharomyces cerevisiae S288C	48-53
617788-3	1977	(2) Prothrombin in the factor IX concentrate could be converted to thrombin without any additional procoagulant such as thromboplastin or factor V, but in just 2.5M glycine solution by the effect of factor Xa.	Glycine	165-172	prothrombin	Oryctolagus cuniculus	7-15
12549040-7	2000	One of the base-pair substitution in exon 8 is a missense mutation, which changed codon 304 of PTEN protein from Cys to Gly.	Glycine	120-123	phosphatase and tensin homolog	Homo sapiens	95-99
844795-2	1977	Furthermore, serum immunoreactive gastrin levels were higher in the absence than in the presence of the thyroid gland following the oral administration of glycine or rat chaw.	Glycine	155-162	gastrin	Rattus norvegicus	34-41
12509-3	1976	The uptake of glycine was also Na+ gradient dependent, and exhibited a two Km system, Km1 = 0.22 mM and Km2 = 4.00 mM.	Glycine	14-21	Kidney mass QTL 2	Rattus norvegicus	104-107
33835003-13	2020	A heterozygous single nucleotide substitution c.6127G>A in exon 73 of COL7A1 was found, which converts glycine to arginine residue, designated p. G2043R.	Glycine	103-110	collagen type VII alpha 1 chain	Homo sapiens	70-76
11035260-1	2000	The thioredoxins are ubiquitous proteins containing a conserved -Trp-Cys-Gly-Pro-Cys-Lys- redox catalytic site.	Glycine	73-76	thioredoxin	Homo sapiens	4-16
33039564-6	2020	The docking studies revealed that the ligands made strong interactions with the catalytic site residues TRP30, TYR 32, GLY 71, TRP 74, GLY 76, ALA 77 and GLU 136 of MmaA1 protein.	Glycine	119-122	mycolic acid methyltransferase MmaA1	Mycobacterium tuberculosis H37Rv	165-170
33039564-6	2020	The docking studies revealed that the ligands made strong interactions with the catalytic site residues TRP30, TYR 32, GLY 71, TRP 74, GLY 76, ALA 77 and GLU 136 of MmaA1 protein.	Glycine	135-138	mycolic acid methyltransferase MmaA1	Mycobacterium tuberculosis H37Rv	165-170
823150-5	1976	During the sequence work on human carbonic anhydrase C, 3 very easily deamidated asparagine residues were noted, all occurring in -Asn-Gly- sequences.	Glycine	135-138	carbonic anhydrase 2	Homo sapiens	34-54
1220690-4	1975	The observations suggest a route for the incorporation of glutamate carbon into glycine that involves C-5 but not C-2.	Glycine	80-87	complement C5	Cavia porcellus	102-105
32686895-7	2020	Using a combination of molecular docking and biochemical assays, we found that Gln 116 , Phe 119 and Gly 120 of LC3-PE are required for the cleavage by both RavZ and ATG4B, while Glu 117 (LC3) is specific for the cleavage by RavZ.	Glycine	101-104	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	112-115
10916091-6	2000	Next, using cultured human mesangial cells, we investigated the role of Gly-Alb and/or HG on the gene and protein expression of MCP-1.	Glycine	72-75	C-C motif chemokine ligand 2	Homo sapiens	128-133
33106247-7	2020	The G4-associated genome instability and the G4 DNA-binding in vivo requires the arginine-glycine-glycine (RGG) repeats located at the C-terminus of the Nsr1 protein.	Glycine	90-97	Nsr1p	Saccharomyces cerevisiae S288C	153-157
236734-3	1975	Liver enzymatic studies showed decreased activity in vitro of the glycine cleavage enzyme in one patient with methylmalonic acidaemia as well as in 2 unrelated patients with nonketotic hyperglycinaemia, while the activity of the serine hydroxymethylase enzyme was normal.	Glycine	66-73	serine hydroxymethyltransferase 2	Homo sapiens	229-252
10887113-7	2000	Through these interactions, HKa or its recombinant His-Gly-Lys-rich domain 5 completely inhibited the uPAR-dependent adhesion of myelomonocytic U937 cells and uPAR-transfected BAF-3 cells to VN and thereby promoted cell detachment.	Glycine	55-58	plasminogen activator, urokinase receptor	Homo sapiens	102-106
24419545-5	1974	As well as lysine, the content of other amino acids, such as aspartic acid, arginine, glycine, threonine, valine and histidine are also, in general, increased by the presence of the o 2 gene in recessive homozygous condition.The results obtained have shown that a number of correlation coefficients between the protein quality traits and yield components related to kernel characteristics are negative and significant, especially in the presence of the o 2 gene in recessive homozygous condition.	Glycine	86-93	regulatory protein opaque-2	Zea mays	182-185
10887113-7	2000	Through these interactions, HKa or its recombinant His-Gly-Lys-rich domain 5 completely inhibited the uPAR-dependent adhesion of myelomonocytic U937 cells and uPAR-transfected BAF-3 cells to VN and thereby promoted cell detachment.	Glycine	55-58	plasminogen activator, urokinase receptor	Homo sapiens	159-163
10781610-4	2000	Changing Glu-226, which corresponded to the catalytic residue of the cyclase, to Asp, Asn, Gln, Leu, or Gly eliminated essentially all enzymatic activities of CD38, indicating it is most likely the catalytic residue.	Glycine	104-107	CD38 molecule	Homo sapiens	159-163
5279520-0	1971	Regulation of rat liver glutamine synthetase: activation by alpha-ketoglutarate and inhibition by glycine, alanine, and carbamyl phosphate.	Glycine	98-105	glutamate-ammonia ligase	Rattus norvegicus	24-44
32916306-9	2020	Furthermore, changes in the plasma metabolites glycine, betaine, methionine and lysine (associated with the S-adenosylmethionine cycle) were also associated with altered striatal DAT expression.	Glycine	47-54	solute carrier family 6 member 3	Homo sapiens	179-182
11104840-6	2000	A trend toward an excess of DRD3 genotype Gly/Gly was observed in neuroleptic nonresponder schizophrenic patients compared to controls (chi(2)=3.	Glycine	42-45	dopamine receptor D3	Homo sapiens	28-32
33842008-14	2021	Conclusion: Our data suggest a novel interaction between alpha1 GlyR subunits and collybistin, which is physiologically relevant in vitro and in vivo and may contribute to postsynaptic anchoring of glycine receptors.	Glycine	198-205	Cdc42 guanine nucleotide exchange factor 9	Homo sapiens	82-93
13397493-0	1957	Effect of estrogen and androgen upon uptake of glycine-C14 by rat uteri in vitro:  lack of concentration dependence.	Glycine	47-54	anti-Mullerian hormone receptor type 2	Rattus norvegicus	55-58
11104840-6	2000	A trend toward an excess of DRD3 genotype Gly/Gly was observed in neuroleptic nonresponder schizophrenic patients compared to controls (chi(2)=3.	Glycine	46-49	dopamine receptor D3	Homo sapiens	28-32
32948689-5	2020	GRIP1 is recruited into synapses during LTP, and deletion of Grip1 in neurons blocks synaptic AMPAR accumulation induced by glycine-mediated depolarization.	Glycine	124-131	glutamate receptor interacting protein 1	Mus musculus	0-5
32948689-5	2020	GRIP1 is recruited into synapses during LTP, and deletion of Grip1 in neurons blocks synaptic AMPAR accumulation induced by glycine-mediated depolarization.	Glycine	124-131	glutamate receptor interacting protein 1	Mus musculus	61-66
33249721-5	2021	In the closed conformation stabilized by glycine - an active-site ligand of hSR - the side chain of Lys114 moves away from that of Cys113, while the carboxyl side-chain group of Asp318 moves significantly closer, increasing the thiol pKa and preventing the reaction.	Glycine	41-48	HSR	Homo sapiens	76-79
10749851-9	2000	Deletion studies demonstrated that the COOH-terminal region of ILF3, which is rich in arginine, glycine, and serine, is responsible for the strong interaction between PRMT1 and ILF3 and is the site of ILF3 methylation by PRMT1.	Glycine	96-103	interleukin enhancer binding factor 3	Homo sapiens	63-67
33249721-6	2021	We conclude that ATP binding, glycine binding, and S-nitrosylation constitute a three-way regulation mechanism for the tight control of hSR activity.	Glycine	30-37	HSR	Homo sapiens	136-139
32917219-0	2020	Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-kappabeta pathway.	Glycine	9-16	TNF receptor superfamily member 1A	Rattus norvegicus	113-118
10749851-9	2000	Deletion studies demonstrated that the COOH-terminal region of ILF3, which is rich in arginine, glycine, and serine, is responsible for the strong interaction between PRMT1 and ILF3 and is the site of ILF3 methylation by PRMT1.	Glycine	96-103	interleukin enhancer binding factor 3	Homo sapiens	177-181
33914976-0	2021	Single glycine deletion in COL7A1 acting as glycine substitution in dystrophic epidermolysis bullosa.	Glycine	7-14	collagen type VII alpha 1 chain	Homo sapiens	27-33
10749851-9	2000	Deletion studies demonstrated that the COOH-terminal region of ILF3, which is rich in arginine, glycine, and serine, is responsible for the strong interaction between PRMT1 and ILF3 and is the site of ILF3 methylation by PRMT1.	Glycine	96-103	interleukin enhancer binding factor 3	Homo sapiens	177-181
33914976-0	2021	Single glycine deletion in COL7A1 acting as glycine substitution in dystrophic epidermolysis bullosa.	Glycine	44-51	collagen type VII alpha 1 chain	Homo sapiens	27-33
32769979-1	2020	GABAA/glycine-mediated neuronal inhibition critically depends on intracellular chloride (Cl-) concentration which is mainly regulated by the K+-Cl- co-transporter 2 (KCC2) in the adult central nervous system (CNS).	Glycine	6-13	solute carrier family 12 member 5	Homo sapiens	141-164
33914976-3	2021	We report a novel COL7A1 single glycine deletion exerting the same pathological effect as glycine substitutions in its triple-helical domain (THD).	Glycine	32-39	collagen type VII alpha 1 chain	Homo sapiens	18-24
32769979-1	2020	GABAA/glycine-mediated neuronal inhibition critically depends on intracellular chloride (Cl-) concentration which is mainly regulated by the K+-Cl- co-transporter 2 (KCC2) in the adult central nervous system (CNS).	Glycine	6-13	solute carrier family 12 member 5	Homo sapiens	166-170
10879540-5	2000	Here we report that the phenotypes associated with a single point mutation at the intramembranous processing site of Notch1, Val1,744--&gt;Gly, resemble the null Notch1 phenotype.	Glycine	139-142	notch 1	Mus musculus	117-123
32614601-2	2020	Previous research illustrated that the osmolyte glycine (Gly) reduced porcine parvovirus (PPV) infection in porcine kidney (PK-13) cells by stabilizing the capsid protein and preventing virus capsid assembly into viable virus particles.	Glycine	57-60	THO complex 5	Homo sapiens	124-129
33914976-3	2021	We report a novel COL7A1 single glycine deletion exerting the same pathological effect as glycine substitutions in its triple-helical domain (THD).	Glycine	90-97	collagen type VII alpha 1 chain	Homo sapiens	18-24
33358811-6	2021	The amino acid at site 158 of beta-Lg E was Gly (G) in yak but Glu (E) in bovine.	Glycine	44-47	beta-lactoglobulin	Bos taurus	30-37
10879540-5	2000	Here we report that the phenotypes associated with a single point mutation at the intramembranous processing site of Notch1, Val1,744--&gt;Gly, resemble the null Notch1 phenotype.	Glycine	139-142	notch 1	Mus musculus	162-168
33259793-3	2021	These events depend on the CAP-Gly motif found in dTBCE and are regulated by Ran and lamin proteins.	Glycine	31-34	Ran	Drosophila melanogaster	77-80
10748206-5	2000	In PTPalpha, this residue is a glutamine causing steric hindrance and in PTP1B a glycine allowing broad substrate recognition.	Glycine	81-88	protein phosphatase 2 phosphatase activator	Homo sapiens	3-11
33498415-7	2021	In experimental periodontitis, administering GLY extracts significantly decreases the number of TRAP-positive osteoclasts in the alveolar bone on day 4, and significantly inhibits the ligature-induced bone resorption on day 20.	Glycine	45-48	acid phosphatase 5, tartrate resistant	Mus musculus	96-100
33086983-5	2021	Introducing three glycine residues that disrupt a rigid IS6-AID helix markedly reduced basal open probability despite intact binding of CaVbeta to alpha1C I-II loop, and eliminated beta-adrenergic agonist stimulation of CaV1.2 current.	Glycine	18-25	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	220-226
33413684-7	2021	In particular, serine, glycine, and proline metabolism, and the anabolic potential of the cell, were sensitive to PEPCK-M activity.	Glycine	23-30	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	114-121
33351169-4	2021	Glycine transporter 1 (GlyT-1) inhibitors, which raise extracellular glycine levels, have repeatedly been shown to decrease ethanol intake in the rat.	Glycine	69-76	solute carrier family 6 member 9	Rattus norvegicus	0-21
33351169-4	2021	Glycine transporter 1 (GlyT-1) inhibitors, which raise extracellular glycine levels, have repeatedly been shown to decrease ethanol intake in the rat.	Glycine	69-76	solute carrier family 6 member 9	Rattus norvegicus	23-29
33203732-0	2021	Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth.	Glycine	79-86	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	45-49
33456583-1	2021	Introduction: Serine hydroxymethyltransferase 2 (SHMT2) plays a critical role in serine-glycine metabolism to drive cancer cell proliferation.	Glycine	88-95	serine hydroxymethyltransferase 2	Homo sapiens	14-47
33456583-1	2021	Introduction: Serine hydroxymethyltransferase 2 (SHMT2) plays a critical role in serine-glycine metabolism to drive cancer cell proliferation.	Glycine	88-95	serine hydroxymethyltransferase 2	Homo sapiens	49-54
32668192-4	2020	Here, we demonstrate that TGF-beta promotes accumulation of ATF4 (activating transcription factor 4), which is required for increased expression of the serine-glycine synthesis pathway enzymes in response to TGF-beta.	Glycine	159-166	activating transcription factor 4	Homo sapiens	60-64
32668192-4	2020	Here, we demonstrate that TGF-beta promotes accumulation of ATF4 (activating transcription factor 4), which is required for increased expression of the serine-glycine synthesis pathway enzymes in response to TGF-beta.	Glycine	159-166	activating transcription factor 4	Homo sapiens	66-99
32199697-5	2020	RESULTS: The liver expression levels of APOA1bp were associated with lower cIMT and leukocyte counts, a better plasma lipid profile and higher circulating levels of metabolites associated with lower risk of atherosclerosis (glycine, histidine and asparagine).	Glycine	224-231	NAD(P)HX epimerase	Homo sapiens	40-47
31677348-6	2020	Furthermore, sRAGE was also higher in those that did not carry the A allele of the RAGE gene that codes for serine instead of glycine (p = 0.034).	Glycine	126-133	long intergenic non-protein coding RNA 914	Homo sapiens	14-18
32903271-5	2020	Decreased glycine in the HeLa cell-based xenograft tumors with knocked down SHMT2 was potentiated by administration of the anti-hyperglycinemia agent benzoate.	Glycine	10-17	serine hydroxymethyltransferase 2	Homo sapiens	76-81
32753055-6	2020	Greater toxicity correlated with a short and unstructured carboxyl terminus (C-terminus) in the glycine-arginine (GR) RAN protein reading frame.	Glycine	96-103	Ran	Drosophila melanogaster	118-121
32614601-2	2020	Previous research illustrated that the osmolyte glycine (Gly) reduced porcine parvovirus (PPV) infection in porcine kidney (PK-13) cells by stabilizing the capsid protein and preventing virus capsid assembly into viable virus particles.	Glycine	48-55	THO complex 5	Homo sapiens	124-129
32586831-5	2020	Changing the evolutionarily conserved glycine 127 in mouse Fxn to valine results in a failure to thrive phenotype in homozygous animals and a substantially reduced number of offspring.	Glycine	38-45	frataxin	Mus musculus	59-62
32699277-3	2020	A previous study found variants in genes associated with glycine-serine metabolism (PSPH, PHGDH and CPS1) to be associated with MacTel, and showed low levels of glycine and serine in the serum of MacTel patients.	Glycine	57-64	phosphoserine phosphatase	Homo sapiens	84-88
32699277-3	2020	A previous study found variants in genes associated with glycine-serine metabolism (PSPH, PHGDH and CPS1) to be associated with MacTel, and showed low levels of glycine and serine in the serum of MacTel patients.	Glycine	161-168	phosphoserine phosphatase	Homo sapiens	84-88
32555167-9	2020	The present data support a facilitating role of glycine and cAMP on network oscillations and synaptic efficacy at the CA3-CA1 circuit in rats, whereas raising endogenous D-serine levels had no such beneficial effects.	Glycine	48-55	carbonic anhydrase 3	Rattus norvegicus	118-121
32496219-7	2020	A large 30-amino-acid glycine- and alanine-rich central loop, which is unique to mammalian PATZ1 amongst all ZBTB proteins, could not be resolved, probably owing to its flexibility.	Glycine	22-29	POZ/BTB and AT hook containing zinc finger 1	Homo sapiens	91-96
32236580-7	2020	By fusing two copies of the 14-3-3zeta gene, via a Gly-rich linker, a non-dissociable dimer of 14-3-3zeta was formed.	Glycine	51-54	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	Homo sapiens	28-38
32236580-7	2020	By fusing two copies of the 14-3-3zeta gene, via a Gly-rich linker, a non-dissociable dimer of 14-3-3zeta was formed.	Glycine	51-54	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	Homo sapiens	95-105
32486091-3	2020	This sensory material is exploited in the selectivity detection of glycine in complex mixtures of amino acids mimicking elastin, collagen and epidermis, and also in following the protease activity in a beefsteak and chronic human wounds.	Glycine	67-74	elastin	Homo sapiens	120-127
32377452-3	2020	An additional N-terminal glycine-arginine-rich (GAR) domain is present in the FBL of eukaryotes.	Glycine	25-32	fibrillarin	Homo sapiens	78-81
32336957-5	2020	The results revealed that the identified ORF1ab polyprotein belongs to a part of nonstructural protein 1 (nsp1) with the high antigenicity residues in a glycine-proline or hydrophobic amino acid rich domain.	Glycine	153-160	SH2 domain containing 3A	Homo sapiens	106-110
32110933-5	2020	Results showed that glycine pretreatment attenuated LPS-induced decreases of mucin at both protein and mRNA levels, reduced LPS-triggered upregulation of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), interferons, granulocyte-macrophage colony-stimulating factor (GM-CSF), and interleukins.	Glycine	20-27	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	244-292
32110933-5	2020	Results showed that glycine pretreatment attenuated LPS-induced decreases of mucin at both protein and mRNA levels, reduced LPS-triggered upregulation of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), interferons, granulocyte-macrophage colony-stimulating factor (GM-CSF), and interleukins.	Glycine	20-27	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	294-300
31673914-8	2020	A comparison of enzyme activities showed that the activity of ZmTMT was higher than that of GmTMT2a (Glycine max) and AtTMT (Arabidopsis thaliana).	Glycine	101-108	Probable tocopherol O-methyltransferase, chloroplastic	Zea mays	62-67
31991880-5	2020	mRNA expression of the creatine synthesizing enzymes arginine:glycine aminotransferase (GATM) and guanidinoacetate methyltransferase (GAMT), the creatine transporter (SLC6A8), and the creatine kinases (mitochondrial CKMT1A & cytosolic BBCK) was assessed.	Glycine	62-69	glycine amidinotransferase	Homo sapiens	88-92
31998075-10	2019	Finally, tiRNA-Gly-GCC-001 was identified to target BDNF using the luciferase reporter assay.	Glycine	15-18	brain-derived neurotrophic factor	Rattus norvegicus	52-56
31998075-11	2019	In summary, we found an altered tsRNA expression pattern and predicted tiRNA-Gly-GCC-001 might be involved in the MAPK and neurotrophin pathways by targeting the BDNF, thus regulating the post-SCI pathophysiologic processes.	Glycine	77-80	brain-derived neurotrophic factor	Rattus norvegicus	162-166
31707355-2	2020	Mitochondrial C1 metabolism including serine hydroxymethyltransferase 2 (SHMT2) generates glycine for de novo purine nucleotide and glutathione biosynthesis, and is an important source of NADPH, ATP, and formate, which affords C1 units as 10-formyl-tetrahydrofolate and 5,10-methylene-tetrahydrofolate for nucleotide biosynthesis in the cytosol.	Glycine	90-97	serine hydroxymethyltransferase 2	Homo sapiens	38-71
31707355-2	2020	Mitochondrial C1 metabolism including serine hydroxymethyltransferase 2 (SHMT2) generates glycine for de novo purine nucleotide and glutathione biosynthesis, and is an important source of NADPH, ATP, and formate, which affords C1 units as 10-formyl-tetrahydrofolate and 5,10-methylene-tetrahydrofolate for nucleotide biosynthesis in the cytosol.	Glycine	90-97	serine hydroxymethyltransferase 2	Homo sapiens	73-78
33569544-6	2020	SHMT2 catalyzes the conversion of serine to glycine and produces an activated one-carbon unit that can be used to support S-adenosyl methionine synthesis.	Glycine	44-51	serine hydroxymethyltransferase 2	Homo sapiens	0-5
31748411-4	2019	KIF3C is of particular interest because it exhibits a signature 25-residue insert of glycine and serine residues in loop L11 of its motor domain, and this insert is not present in any other kinesin, suggesting that it confers specific properties to mammalian heterodimeric KIF3AC.	Glycine	85-92	kinesin family member 3C	Homo sapiens	0-5
32691412-6	2021	Result shows that mutation of folE protein at 52th residue from tyrosine to glycine or variation in pH and temp can lead to high destability in protein structure.	Glycine	76-83	GTP cyclohydrolase I	Mycobacterium tuberculosis H37Rv	30-34
32688289-1	2020	PURPOSE: Integrin alphavbeta3, a member of the arginine-glycine-aspartate (RGD)-binding subfamily, is associated with tumor angiogenesis and metastasis.	Glycine	56-63	integrin subunit alpha V	Homo sapiens	9-29
32625101-7	2020	In particular, among the nine conjugated peptides tested, caffeic acid linked to a Gly-Gly-Gly linker and conjugated to the tripeptide, ARP, showed the greatest inhibition of gene expression in the qRT-PCR analysis.	Glycine	83-86	arginine-glutamic acid dipeptide repeats	Homo sapiens	136-139
32625101-7	2020	In particular, among the nine conjugated peptides tested, caffeic acid linked to a Gly-Gly-Gly linker and conjugated to the tripeptide, ARP, showed the greatest inhibition of gene expression in the qRT-PCR analysis.	Glycine	87-90	arginine-glutamic acid dipeptide repeats	Homo sapiens	136-139
32625101-7	2020	In particular, among the nine conjugated peptides tested, caffeic acid linked to a Gly-Gly-Gly linker and conjugated to the tripeptide, ARP, showed the greatest inhibition of gene expression in the qRT-PCR analysis.	Glycine	87-90	arginine-glutamic acid dipeptide repeats	Homo sapiens	136-139
32142918-8	2020	Similar to its family member SHMT2, SHMT1 plays a crucial role in folate-dependent serine/glycine inter-conversion in one-carbon metabolism.	Glycine	90-97	serine hydroxymethyltransferase 2	Homo sapiens	29-34
32326652-0	2020	Heterologous Expression of a Glycine soja C2H2 Zinc Finger Gene Improves Aluminum Tolerance in Arabidopsis.	Glycine	29-36	6	Arabidopsis thaliana	42-46
31634165-4	2020	The emergence of this particular glycine substitution in patients from diverse ethnic backgrounds such as China, United Kingdom, Poland, Iran, and Pakistan indicates that this variant most likely constitutes a recurrent mutational hotspot in the COL7A1 gene, rather than a germline mutation present at low levels in the general population.	Glycine	33-40	collagen type VII alpha 1 chain	Homo sapiens	246-252
31948748-5	2020	The ABCB5/STAT1 high-expressing clones showed higher cellular levels of Ala, Glu, and Asp and lower cellular levels of Phe, Trp, Leu, Ile, Gly, Met, Tyr, Val, and His compared to the ABCB5/STAT1 low-expressing clones.	Glycine	139-142	signal transducer and activator of transcription 1	Homo sapiens	10-15
31687740-1	2020	BACKGROUND: Arginine:glycine amidinotransferase, necessary for the conversion of arginine (Arg) to guanidinoacetic acid (GAA), is expressed mainly in kidney and pancreas.	Glycine	21-28	alpha glucosidase	Sus scrofa	121-124
31898422-11	2020	The results suggested that COL1A1 novel mutations were in highly conserved glycine residues present in the Gly-X-Y sequence repeats of the triple helical region of the collagen type I alpha chain, which was responsible for Osteogenesis Imperfecta.	Glycine	75-82	collagen type I alpha 1 chain	Homo sapiens	27-33
31898422-11	2020	The results suggested that COL1A1 novel mutations were in highly conserved glycine residues present in the Gly-X-Y sequence repeats of the triple helical region of the collagen type I alpha chain, which was responsible for Osteogenesis Imperfecta.	Glycine	107-110	collagen type I alpha 1 chain	Homo sapiens	27-33
31812689-5	2020	In Arabidopsis, AtSRBP1 is a glycine-rich RNA-binding protein, also known as AtGRP7, which we show binds single-stranded-siRNA.	Glycine	29-36	cold, circadian rhythm, and rna binding 2	Arabidopsis thaliana	77-83
30652647-10	2020	Molecular docking studies on EGFR (PDB ID: 1M17) results, the compounds 6d, 6j and 6l showed good dock/PLP scores i.e.-81.28, -73.98 and -75.37 by interacting with Leu-694, Val-702and Gly-772 amino acids via hydrophobic and hydrogen bonds with Asn818 and Met-769.	Glycine	184-187	proteolipid protein 1	Homo sapiens	103-106
31260673-5	2020	CENPV, a constituent of mitotic chromosomes associating with cytoplasmic microtubules, interacts with CYLD through the region between the third cytoskeleton-associated protein-glycine domain and the active site.	Glycine	176-183	CYLD lysine 63 deubiquitinase	Homo sapiens	102-106
31955980-6	2020	In line with reported pathogenic mutations in the glycine/phenylalanine (G/F) domain of DNAJB6, both the novel mutations showed reduced anti-aggregation capacity by filter trap assay and TDP-43 disaggregation assays.	Glycine	50-57	DnaJ heat shock protein family (Hsp40) member B6	Homo sapiens	88-94
31540874-5	2019	FBL diffuses to the DFC, where local self-association via its glycine- and arginine-rich (GAR) domain forms phase-separated clusters to immobilize FBL-interacting pre-rRNA, thus promoting directional traffic of nascent pre-rRNA while facilitating pre-rRNA processing and DFC formation.	Glycine	62-69	fibrillarin	Homo sapiens	0-3
31487503-10	2019	Together, this study provides first evidence that the carboxyl-terminal region of KIF13B containing the CAP-Gly domain is important for the LRP1-DLG1-KIF13B complex formation with implications in the regulation of metabolism, cell polarity, and development.	Glycine	108-111	low density lipoprotein receptor-related protein 1	Mus musculus	140-144
10871840-5	2000	The insulin stimulated or Src/Fyn-mediated tyrosine phosphorylation in vivo was significantly reduced when Grb10 tyrosine 67 was changed to glycine.	Glycine	140-147	FYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	30-33
10871840-5	2000	The insulin stimulated or Src/Fyn-mediated tyrosine phosphorylation in vivo was significantly reduced when Grb10 tyrosine 67 was changed to glycine.	Glycine	140-147	growth factor receptor bound protein 10	Homo sapiens	107-112
31773687-2	2019	Mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in the synthesis of serine and glycine, which has prognostic and therapeutic value for many malignant tumors.	Glycine	103-110	serine hydroxymethyltransferase 2	Homo sapiens	49-54
10818139-1	2000	We have used site-directed mutagenesis in conjunction with homologous recombination to generate two mouse lines carrying point mutations in the glycine binding site of the NMDAR1 subunit (Grin1).	Glycine	144-151	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	172-178
10818139-1	2000	We have used site-directed mutagenesis in conjunction with homologous recombination to generate two mouse lines carrying point mutations in the glycine binding site of the NMDAR1 subunit (Grin1).	Glycine	144-151	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	188-193
10818139-2	2000	Glycine concentration-response curves from acutely dissociated hippocampal neurons revealed a 5- and 86-fold reduction in receptor glycine affinity in mice carrying Grin1(D481N) and Grin1(K483Q) mutations, respectively, whereas receptor glutamate affinity remained unaffected.	Glycine	0-7	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	165-170
10818139-2	2000	Glycine concentration-response curves from acutely dissociated hippocampal neurons revealed a 5- and 86-fold reduction in receptor glycine affinity in mice carrying Grin1(D481N) and Grin1(K483Q) mutations, respectively, whereas receptor glutamate affinity remained unaffected.	Glycine	0-7	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	182-187
10828966-3	2000	In the present studies, we have examined the regulation of ANP-C receptor-adenylyl cyclase signal transduction by ANP and [des(Gln(18),Ser(19),Gln(20),Leu(21), Gly(22))ANP(4-23)-NH(2)](C-ANP(4-23)) that interacts specifically with ANP-C receptor in A10 smooth muscle cells (SMC).	Glycine	160-163	natriuretic peptide receptor 3	Homo sapiens	59-64
31545450-3	2019	SARDH is involved in the metabolism of the glycine-derivative sarcosine and is closely linked through a functional control loop.	Glycine	43-50	sarcosine dehydrogenase	Homo sapiens	0-5
10744740-5	2000	The primary mutations in atp1-1 and atp1-2 were identified as Thr(383) --&gt; Ile and Gly(291) --&gt; Asp, respectively.	Glycine	86-89	Atp11p	Saccharomyces cerevisiae S288C	25-31
31628376-1	2019	The neuronal glycine transporter GlyT2 is an essential regulator of glycinergic neurotransmission that recaptures glycine in presynaptic terminals to facilitate transmitter packaging in synaptic vesicles.	Glycine	13-20	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	33-38
31628376-1	2019	The neuronal glycine transporter GlyT2 is an essential regulator of glycinergic neurotransmission that recaptures glycine in presynaptic terminals to facilitate transmitter packaging in synaptic vesicles.	Glycine	68-75	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	33-38
10744740-8	2000	An unlinked suppressor gene, ASC1 (alpha-subunit complementing) of the atp1-2 mutation (Gly(291) --&gt; Asp) restored the growth defect phenotype on glycerol, but did not suppress either atp1-1 or the deletion mutant Deltaatp1.	Glycine	88-91	Atp11p	Saccharomyces cerevisiae S288C	187-193
31628376-2	2019	Alterations in GlyT2 expression or activity result in lower cytosolic glycine levels, emptying glycinergic synaptic vesicles and impairing neurotransmission.	Glycine	70-77	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	15-20
31628376-8	2019	This work identifies, to our knowledge, the first E3 ubiquitin-ligases acting on GlyT2, revealing a novel molecular mechanism that controls presynaptic glycine availability.	Glycine	152-159	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	81-86
10742114-8	2000	The third is a missense mutation in a highly conserved glycine residue of the fifth epidermal growth factor (EGF) repeat, which has revealed an important functional role for this domain.	Glycine	55-62	epidermal growth factor	Homo sapiens	84-107
31624291-0	2019	Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver.	Glycine	60-67	aldehyde dehydrogenase 1 family, member L1	Mus musculus	0-49
31624291-7	2019	A two-fold decrease in glycine and a strong drop in glycine conjugates, a likely result of glycine shortage, were also observed in Aldh1l1-/- mice.	Glycine	23-30	aldehyde dehydrogenase 1 family, member L1	Mus musculus	131-138
31624291-7	2019	A two-fold decrease in glycine and a strong drop in glycine conjugates, a likely result of glycine shortage, were also observed in Aldh1l1-/- mice.	Glycine	52-59	aldehyde dehydrogenase 1 family, member L1	Mus musculus	131-138
31624291-7	2019	A two-fold decrease in glycine and a strong drop in glycine conjugates, a likely result of glycine shortage, were also observed in Aldh1l1-/- mice.	Glycine	52-59	aldehyde dehydrogenase 1 family, member L1	Mus musculus	131-138
10742114-8	2000	The third is a missense mutation in a highly conserved glycine residue of the fifth epidermal growth factor (EGF) repeat, which has revealed an important functional role for this domain.	Glycine	55-62	epidermal growth factor	Homo sapiens	109-112
10698713-4	2000	By using a PTEN G129E (Gly(129)--&gt;Glu) mutant that has lost its lipid phosphatase activity, while retaining protein phosphatase activity, we demonstrated a requirement for the lipid phosphatase activity of PTEN in the regulation of PKB activity, cell viability and membrane ruffling.	Glycine	23-26	phosphatase and tensin homolog	Homo sapiens	11-15
31176036-3	2019	In this study, we assessed the effects of taurine- or glycine-conjugated cholate, ursodeoxycholate and hyodeoxycholate on the ABCB4-mediated phosphatidylcholine (PC) efflux using Abcb4 knockout mice and HEK293 cells stably expressing ABCB4.	Glycine	54-61	ATP binding cassette subfamily B member 4	Homo sapiens	234-239
10722844-3	2000	Co-transfection of syntaxin 1A with GLYT1 or GLYT2 in COS cells resulted in approximately 40% inhibition in glycine transport.	Glycine	108-115	syntaxin 1A	Rattus norvegicus	19-30
31366981-7	2019	Further analysis of the highly similar Cr-AGO2 and Cr-AGO 3 sequences (90% amino acid identity) revealed a glycine-arginine rich N-terminal extension of ~100 amino acids that, given previous work on unicellular protists, may associate AGO with the translation machinery.	Glycine	107-114	uncharacterized protein	Chlamydomonas reinhardtii	42-46
10722844-3	2000	Co-transfection of syntaxin 1A with GLYT1 or GLYT2 in COS cells resulted in approximately 40% inhibition in glycine transport.	Glycine	108-115	solute carrier family 6 member 5	Rattus norvegicus	45-50
10814090-6	2000	The Leu-enkephalin analogues were tested in a panel of binding and functional assays, and although those derivatives containing cyclopropane replacements of the Gly(2)-Gly(3) exhibited low micromolar affinity for the mu-receptor, analogues containing such replacements for the Phe(4)-Leu(5) subunit did not bind with significant affinity to any of the opioid receptors.	Glycine	161-164	prodynorphin	Homo sapiens	4-18
31028716-2	2019	AGAT also catalyzes the formation of guanidinoacetate (GAA) from Arg and glycine (Gly).	Glycine	73-80	glycine amidinotransferase	Homo sapiens	0-4
31699086-6	2019	Next, we developed an assay for multiple metabolites including ALA and found that aconitase, encoded by ACO1 and ACO2, is the rate-limiting enzyme of ALA biosynthesis when sufficient glycine is supplied.	Glycine	183-190	aconitate hydratase ACO1	Saccharomyces cerevisiae S288C	104-108
31699086-6	2019	Next, we developed an assay for multiple metabolites including ALA and found that aconitase, encoded by ACO1 and ACO2, is the rate-limiting enzyme of ALA biosynthesis when sufficient glycine is supplied.	Glycine	183-190	aconitate hydratase ACO2	Saccharomyces cerevisiae S288C	113-117
31028716-2	2019	AGAT also catalyzes the formation of guanidinoacetate (GAA) from Arg and glycine (Gly).	Glycine	82-85	glycine amidinotransferase	Homo sapiens	0-4
30964837-3	2019	Serine hydroxymethyl-transferase 2 (SHMT2) serves as the key enzyme in the biosynthesis of glycine.	Glycine	91-98	serine hydroxymethyltransferase 2	Homo sapiens	36-41
11343580-1	2000	This study was undertaken to re-examine whether homozygosity for the Gly-9 variant (allele 2) of the dopamine D3 receptor gene (DRD3) is associated with increased risk for tardive dyskinesia (TD) in schizophrenic patients.	Glycine	69-72	dopamine receptor D3	Homo sapiens	128-132
30964837-9	2019	RESULTS: After PH, the expression levels of SHMT2 fluctuated with time and knockdown of SHMT2 in vivo lowered the regenerative ability of liver, with reduced glycine levels compared to the scramble group.	Glycine	158-165	serine hydroxymethyltransferase 2	Homo sapiens	88-93
31558619-0	2019	Phosphorylation of gephyrin in zebrafish Mauthner cells governs glycine receptor clustering and behavioral desensitization to sound.	Glycine	64-71	gephyrin a	Danio rerio	19-27
31536092-7	2019	Configuration interaction applications to single bond dissociations of water and glycine, and multiple bond dissociations of ethylene and oxygen produce dissociation energy curves in close agreement with CI calculations based on canonical SCF orbitals for the entire range of internuclear distances.	Glycine	81-88	KIT ligand	Homo sapiens	239-242
30964837-10	2019	In addition, overexpression of SHMT2 in hepatocytes boosted glycine production while enhancing Akt/mTOR pathway activity.	Glycine	60-67	serine hydroxymethyltransferase 2	Homo sapiens	31-36
11343580-4	2000	The non-significant tendency in this sample towards an over-representation of allele 2 and the 2-2 genotype among schizophrenic patients with TD is in line with our initial report as well as recent studies by others, indicating that the Gly-9 allele of DRD3 may be a susceptibility factor for the development of TD in neuroleptic-treated individuals with schizophrenia.	Glycine	237-240	dopamine receptor D3	Homo sapiens	253-257
30964837-12	2019	CONCLUSIONS: SHMT2 can contribute to liver regeneration after PH, and this is likely related to the activation of Akt/mTOR signaling pathway by its metabolic product, glycine, in hepatocytes.	Glycine	167-174	serine hydroxymethyltransferase 2	Homo sapiens	13-18
10677220-1	2000	The Ogg1 protein of Saccharomyces cerevisiae belongs to a family of DNA glycosylases and apurinic/apyrimidinic site (AP) lyases, the signature of which is the alpha-helix-hairpin-alpha-helix-Gly/Pro-Asp (HhH-GPD) active site motif together with a conserved catalytic lysine residue, to which we refer as the HhH-GPD/K family.	Glycine	191-194	8-oxoguanine glycosylase OGG1	Saccharomyces cerevisiae S288C	4-8
31186416-5	2019	PSPH upregulation is a general phenomenon in T-ALL patient samples, associated with elevated serine and glycine levels in xenograft mice.	Glycine	104-111	phosphoserine phosphatase	Homo sapiens	0-4
31297861-6	2019	This variant results in a change of a glycine (Gly) to an arginine (Arg) at amino acid position 126 (c.376G&gt;A), occurring in the second Ig-like domain of the extracellular domain of KIT.	Glycine	38-45	mast/stem cell growth factor receptor Kit	Vicugna pacos	185-188
31297861-6	2019	This variant results in a change of a glycine (Gly) to an arginine (Arg) at amino acid position 126 (c.376G&gt;A), occurring in the second Ig-like domain of the extracellular domain of KIT.	Glycine	47-50	mast/stem cell growth factor receptor Kit	Vicugna pacos	185-188
31202607-3	2019	Importantly, GluN1/GluN3A and GluN1/GluN3B receptors form glycine-gated receptors.	Glycine	58-65	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	36-42
31113850-0	2019	mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-beta1-induced collagen biosynthesis.	Glycine	51-58	activating transcription factor 4	Homo sapiens	21-25
10642505-2	2000	The human type I collagen sequence A(1209)HDGGR(1214) of CTx can undergo racemization of the aspartic acid residue Asp(1211) and isomerization of the bond between this residue and Gly(1212).	Glycine	180-183	cytochrome P450 family 27 subfamily A member 1	Homo sapiens	57-60
30983343-10	2019	In contrast, only glycine decreased the expression of MRP2 induced by EC.	Glycine	18-25	ATP binding cassette subfamily C member 2	Homo sapiens	54-58
31443422-7	2019	The code evolved from a proto-tRNA a tetramer XCCA interacting with a proto-aminoacyl-tRNA synthetase (aaRS) activating Glycine and Proline, the initial expanded code is found in the acceptor arm of the tRNA, the operational code.	Glycine	120-127	alanyl-tRNA synthetase 1	Homo sapiens	70-101
31443422-7	2019	The code evolved from a proto-tRNA a tetramer XCCA interacting with a proto-aminoacyl-tRNA synthetase (aaRS) activating Glycine and Proline, the initial expanded code is found in the acceptor arm of the tRNA, the operational code.	Glycine	120-127	alanyl-tRNA synthetase 1	Homo sapiens	103-107
10735633-2	2000	The syndrome was associated with a novel KCNH2 missense mutation, G572R, causing the substitution of a glycine residue at position 572, at the end of the S5 transmembrane segment of the HERG K(+)-channel, with an arginine residue.	Glycine	103-110	potassium voltage-gated channel subfamily H member 2	Homo sapiens	41-46
31366399-3	2019	However, near the onset of the 2009 pandemic, human viruses began to acquire the mammalian-associated residue, glycine, at PB1-216, and PB1-216G became predominant in human viruses thereafter.	Glycine	111-118	submaxillary gland androgen regulated protein 3A	Homo sapiens	123-126
31044171-4	2019	MALDI-MS/MS analysis evidenced post-translational modifications of the signature triplet, Glycine-Proline-Hydroxyproline (G-P-Hyp), in alpha chain of isolated COLII (COLIIA1).	Glycine	90-97	col II	Capra hircus	159-164
10735633-2	2000	The syndrome was associated with a novel KCNH2 missense mutation, G572R, causing the substitution of a glycine residue at position 572, at the end of the S5 transmembrane segment of the HERG K(+)-channel, with an arginine residue.	Glycine	103-110	potassium voltage-gated channel subfamily H member 2	Homo sapiens	186-190
10650926-1	2000	Peptidylglycine alpha-amidating monooxygenase (PAM) is a bifunctional enzyme that catalyzes the carboxyl-terminal amidation of glycine-extended peptides in a two-step reaction involving a monooxygenase and a lyase.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	47-50
31044171-4	2019	MALDI-MS/MS analysis evidenced post-translational modifications of the signature triplet, Glycine-Proline-Hydroxyproline (G-P-Hyp), in alpha chain of isolated COLII (COLIIA1).	Glycine	90-97	col II	Capra hircus	166-173
30483907-7	2019	Western blot analysis showed that 100-200% glycine enhanced the protein levels of occludin, claudin-1, and zonula occludens (ZO)-1 without affecting those of claudin-3, ZO-2, and ZO-3.	Glycine	43-50	claudin 1	Homo sapiens	92-101
30855197-10	2019	Presence of Arg/Gly or Gly/Gly genotypes in position 16 of ADRB2 was significantly associated to a worse BD response (post-BD FEV1: 108.68% +- 15.62% in Arg/Arg vs. 101.86% +- 14.03% in Arg/Gly or Gly/Gly patients, p = 0.02).	Glycine	16-19	adrenoceptor beta 2	Homo sapiens	59-64
30855197-10	2019	Presence of Arg/Gly or Gly/Gly genotypes in position 16 of ADRB2 was significantly associated to a worse BD response (post-BD FEV1: 108.68% +- 15.62% in Arg/Arg vs. 101.86% +- 14.03% in Arg/Gly or Gly/Gly patients, p = 0.02).	Glycine	23-26	adrenoceptor beta 2	Homo sapiens	59-64
30855197-10	2019	Presence of Arg/Gly or Gly/Gly genotypes in position 16 of ADRB2 was significantly associated to a worse BD response (post-BD FEV1: 108.68% +- 15.62% in Arg/Arg vs. 101.86% +- 14.03% in Arg/Gly or Gly/Gly patients, p = 0.02).	Glycine	23-26	adrenoceptor beta 2	Homo sapiens	59-64
30855197-10	2019	Presence of Arg/Gly or Gly/Gly genotypes in position 16 of ADRB2 was significantly associated to a worse BD response (post-BD FEV1: 108.68% +- 15.62% in Arg/Arg vs. 101.86% +- 14.03% in Arg/Gly or Gly/Gly patients, p = 0.02).	Glycine	23-26	adrenoceptor beta 2	Homo sapiens	59-64
30855197-10	2019	Presence of Arg/Gly or Gly/Gly genotypes in position 16 of ADRB2 was significantly associated to a worse BD response (post-BD FEV1: 108.68% +- 15.62% in Arg/Arg vs. 101.86% +- 14.03% in Arg/Gly or Gly/Gly patients, p = 0.02).	Glycine	23-26	adrenoceptor beta 2	Homo sapiens	59-64
30855197-10	2019	Presence of Arg/Gly or Gly/Gly genotypes in position 16 of ADRB2 was significantly associated to a worse BD response (post-BD FEV1: 108.68% +- 15.62% in Arg/Arg vs. 101.86% +- 14.03% in Arg/Gly or Gly/Gly patients, p = 0.02).	Glycine	23-26	adrenoceptor beta 2	Homo sapiens	59-64
30688460-2	2019	Herein, we present the synthesis and antibacterial activities of cholic acid-peptide conjugates (CAPs), demonstrating that valine-glycine dipeptide-derived CAP 3 is the most effective antimicrobial.	Glycine	130-137	serine (or cysteine) peptidase inhibitor, clade B, member 9	Mus musculus	156-161
10669862-0	2000	Mutational analysis of the IgE-binding epitopes of P34/Gly m Bd 30K.	Glycine	55-58	P34 probable thiol protease	Glycine max	51-54
30576625-1	2019	SLC12A5 encodes K+-Cl- cotransporter 2 (KCC2), which is the main Cl- extruder of neurons, and renders the proper inhibitory function of the neurotransmitters gamma-aminobutyric acid (GABA) and glycine.	Glycine	193-200	solute carrier family 12 member 5	Homo sapiens	0-7
30576625-1	2019	SLC12A5 encodes K+-Cl- cotransporter 2 (KCC2), which is the main Cl- extruder of neurons, and renders the proper inhibitory function of the neurotransmitters gamma-aminobutyric acid (GABA) and glycine.	Glycine	193-200	solute carrier family 12 member 5	Homo sapiens	16-38
30576625-1	2019	SLC12A5 encodes K+-Cl- cotransporter 2 (KCC2), which is the main Cl- extruder of neurons, and renders the proper inhibitory function of the neurotransmitters gamma-aminobutyric acid (GABA) and glycine.	Glycine	193-200	solute carrier family 12 member 5	Homo sapiens	40-44
10669862-3	2000	Previous studies have documented multiple allergens in soybean extracts, including glycinin, beta-conglycinin, and the P34/Gly m Bd 30K protein.	Glycine	123-126	P34 probable thiol protease	Glycine max	119-122
30534771-2	2019	The D-RFP was proposed by embedding glycine-derived carbon dots (CDs) (lambdaem = 400 nm) into silica nanoparticles and covalently linking CdTe quantum dots (QDs) (lambdaem = 600 nm) onto the surface of silica nanoparticles.	Glycine	36-43	tripartite motif containing 27	Homo sapiens	6-9
10669862-5	2000	The specific aim of the current investigation was to identify the essential amino acid residues necessary for IgE binding in the 5 distinct immunodominant epitopes of P34/Gly m Bd 30K.	Glycine	171-174	P34 probable thiol protease	Glycine max	167-170
30417726-3	2019	Animal studies consistently have demonstrated a downregulation of KCC2 activity after spinal cord transection, causing a shift from the inhibitory action of gamma-aminobutyric acid and glycine to an excitatory effect.	Glycine	185-192	solute carrier family 12 member 5	Homo sapiens	66-70
10669862-6	2000	METHODS: Serum IgE from 6 clinically sensitive soybean-allergic individuals was used to identify P34/Gly m Bd 30K in the native and single amino acid substituted peptides with use of the SPOTS peptide synthesis technique to determine critical amino acids required for IgE binding.	Glycine	101-104	P34 probable thiol protease	Glycine max	97-100
10938841-5	2000	The amounts of photosynthetic metabolites, including glycine and serine, also showed a biphasic response to decreasing PEPC.	Glycine	53-60	peptidase C	Homo sapiens	119-123
30984480-15	2019	HTU-LOX readily oxidizes various primary amines including such compounds as taurine and glycine, benzylamine being a poor substrate.	Glycine	88-95	lysyl oxidase	Homo sapiens	4-7
30728809-4	2019	Using molecular dynamics simulations, we demonstrate that ABBA binds to the "central cavity" in the elbow of vWbp by interacting with Arg-70, His-71, Ala-72, Gly-73, Tyr-74, Glu-75, Tyr-83, and Gln-87 in vWbp, thus interfering with the binding of vWbp to prothrombin.	Glycine	158-161	MTSS I-BAR domain containing 2	Mus musculus	58-62
10918371-4	2000	These experimental results are entirely consistent with ab initio calculations (at the MP2(full)/6-311G** level) which indicate that while the loss of CO from the b(1) ion of glycine is barrierless and exoethermic, the related losses from the b(1) ions of aziridine and dehydroalanine have significant barriers (29.5 and 16.2 kcal mol(-1), respectively) and are endothermic overall.	Glycine	175-182	tryptase pseudogene 1	Homo sapiens	87-90
30645615-9	2019	The abundance of glycine, proline and aromatic residues in the C-terminal sequences from TAP-independently processed proteins allows the accessibility and specificity required for the proteolytic activities that generates the TAP-independent ligandome.	Glycine	17-24	nuclear RNA export factor 1	Homo sapiens	89-92
30645615-9	2019	The abundance of glycine, proline and aromatic residues in the C-terminal sequences from TAP-independently processed proteins allows the accessibility and specificity required for the proteolytic activities that generates the TAP-independent ligandome.	Glycine	17-24	nuclear RNA export factor 1	Homo sapiens	226-229
30902068-8	2019	The resulting Dr-dUTPase had the leading peptide Gly-Ser-His- originating from the vector at the amino terminus, and a mutation, Arg66Lys, to remove the internal thrombin site.	Glycine	49-52	Deoxyuridine triphosphatase	Drosophila melanogaster	17-24
30710045-0	2019	Glycine Exhibits Neuroprotective Effects in Ischemic Stroke in Rats through the Inhibition of M1 Microglial Polarization via the NF-kappaB p65/Hif-1alpha Signaling Pathway.	Glycine	0-7	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	143-153
30710045-8	2019	We show that glycine suppresses Hif-1alpha by inhibiting the upregulation of NF-kappaB p65 after ischemia-reperfusion injury, resulting in the inhibition of proinflammatory activity.	Glycine	13-20	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	32-42
30710045-9	2019	The activation of AKT mediates the inhibition of NF-kappaB p65/Hif-1alpha signaling by glycine.	Glycine	87-94	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	63-73
30710045-12	2019	Taken together, our findings provide a new understanding of glycine in neuroprotection by inhibiting M1 microglial polarization and promoting anti-inflammation by suppressing NF-kappaB p65/Hif-1alpha signaling.	Glycine	60-67	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	189-199
12075461-1	2000	To set up an in vitro amidating system, a recombinant human calcitonin with a glycine at C termial (mhCT-Gly) was used as the amidating substrate of recombinant rat peptidylglycine alpha-amidating monooxygenase (rPAM).	Glycine	78-85	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	165-210
30845140-9	2019	We find that mutations in components of this cycle, methionine synthase (metr-1) and S-adenosylmethionine synthetase (sams-1), completely abrogate glycine-induced lifespan extension.	Glycine	147-154	putative S-adenosylmethionine synthase 1	Caenorhabditis elegans	118-124
30634695-7	2019	These results indicate that the substitution of Gly at position 187 of ABCC4 to Trp resulted in reduced SN-38 resistance.	Glycine	48-51	ATP binding cassette subfamily C member 4	Homo sapiens	71-76
12075461-1	2000	To set up an in vitro amidating system, a recombinant human calcitonin with a glycine at C termial (mhCT-Gly) was used as the amidating substrate of recombinant rat peptidylglycine alpha-amidating monooxygenase (rPAM).	Glycine	105-108	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	165-210
30361439-4	2018	Here we identified one residue, Gly-129, that contributes to the greater IgG binding affinity of CD16a.	Glycine	32-35	Fc gamma receptor IIIa	Homo sapiens	97-102
30944692-7	2019	The AGE/RAGE signaling pathway in the aorta of diabetic rats was significantly attenuated by glycine treatment as manifested by decreases in levels of AGEs, RAGE, Nox4, and NF-kappaB p65.	Glycine	93-100	NADPH oxidase 4	Rattus norvegicus	163-167
10606722-1	1999	Mutation of glutamic acid 282 of PPARalpha to glycine has been shown to result in an increased EC(50) for a wide variety of PPAR activating compounds.	Glycine	46-53	peroxisome proliferator activated receptor alpha	Homo sapiens	33-42
30448467-1	2019	Vesicular inhibitory amino acid transporter (VIAAT) is a transmembrane transporter which is responsible for the storage of gamma-aminobutyric acid (GABA) or glycine in synaptic vesicles.	Glycine	157-164	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	0-43
30448467-1	2019	Vesicular inhibitory amino acid transporter (VIAAT) is a transmembrane transporter which is responsible for the storage of gamma-aminobutyric acid (GABA) or glycine in synaptic vesicles.	Glycine	157-164	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	45-50
10606722-1	1999	Mutation of glutamic acid 282 of PPARalpha to glycine has been shown to result in an increased EC(50) for a wide variety of PPAR activating compounds.	Glycine	46-53	peroxisome proliferator activated receptor alpha	Homo sapiens	33-37
10654085-7	1999	Except for Dip5p, which is a transporter for Glu, Asp, Gln, Asn, Ser, Ala and Gly, the rest of the permeases exhibit narrow specificity.	Glycine	78-81	Dip5p	Saccharomyces cerevisiae S288C	11-16
30755591-7	2019	Furthermore, the knockdown of LINC01234 induced proliferation arrest via suppressing serine/glycine metabolism.	Glycine	92-99	long intergenic non-protein coding RNA 1234	Homo sapiens	30-39
30385710-4	2018	The molecular characterization of gldc-/- mutants showed a broad metabolic disturbance affecting amino acids and neurotransmitters other than glycine, with lactic acidosis at stages preceding death.	Glycine	142-149	glycine dehydrogenase (decarboxylating)	Danio rerio	34-38
30385710-7	2018	Remarkably, we were able to rescue the motor dysfunction of gldc-/- larvae by counterbalancing pharmacologically or genetically the level of glycine at the synapse.	Glycine	141-148	glycine dehydrogenase (decarboxylating)	Danio rerio	60-64
10545445-6	1999	Interestingly, the prp2-1 allele contains a point mutation that changes glycine to aspartate, indicating that EMT1-201 does not act by classical missense suppression.	Glycine	72-79	Prp21p	Saccharomyces cerevisiae S288C	19-25
10497166-5	1999	These results demonstrate that the reactive center loop sequence determines the specificity of allosterically activated antithrombin for factor Xa and that the conformational flexibility of the P2 Gly may be critical for optimal bridging of antithrombin and thrombin by physiologic heparin and for preventing antithrombin from reacting as a substrate in the bridging complex.	Glycine	197-200	serpin family C member 1	Homo sapiens	120-132
30138575-6	2018	Gly-Sar absorption was decreased in the jejunum of cldn15-/- mice.	Glycine	0-3	claudin 15	Mus musculus	51-57
30011082-6	2018	Results show that the primary interaction of p67phox with Nox2 is followed by a stabilizing step, based on the establishment of disulfide bonds between cysteine(s) in the 369 Cys-Gly-Cys371 triad and cysteine(s) in p67phox .	Glycine	179-182	cytochrome b-245 beta chain	Homo sapiens	58-62
30585221-1	2018	Gly m 5.0101, the alpha subunit of beta-conglycinin, is one of the major allergens found in soybeans that has been identified as causing an allergic reaction.	Glycine	0-3	alpha subunit of beta conglycinin	Glycine max	18-51
10497166-5	1999	These results demonstrate that the reactive center loop sequence determines the specificity of allosterically activated antithrombin for factor Xa and that the conformational flexibility of the P2 Gly may be critical for optimal bridging of antithrombin and thrombin by physiologic heparin and for preventing antithrombin from reacting as a substrate in the bridging complex.	Glycine	197-200	serpin family C member 1	Homo sapiens	241-253
29873416-0	2018	EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis.	Glycine	113-120	Fli-1 proto-oncogene, ETS transcription factor	Homo sapiens	4-8
10497166-5	1999	These results demonstrate that the reactive center loop sequence determines the specificity of allosterically activated antithrombin for factor Xa and that the conformational flexibility of the P2 Gly may be critical for optimal bridging of antithrombin and thrombin by physiologic heparin and for preventing antithrombin from reacting as a substrate in the bridging complex.	Glycine	197-200	serpin family C member 1	Homo sapiens	241-253
29873416-4	2018	Here, we demonstrate that EWS-FLI1 positively regulates the expression of proteins required for serine-glycine biosynthesis and uptake of the alternative nutrient source glutamine.	Glycine	103-110	Fli-1 proto-oncogene, ETS transcription factor	Homo sapiens	30-34
10446221-2	1999	Several missense IGF2R mutations have been identified in human cancers, including the following amino acid substitutions occurring in the extracytoplasmic domain of the receptor: Cys-1262 --&gt; Ser, Gln-1445 --&gt; His, Gly-1449 --&gt; Val, Gly-1464 --&gt; Glu, and Ile-1572 --&gt; Thr.	Glycine	221-224	insulin like growth factor 2 receptor	Homo sapiens	17-22
29948332-2	2018	Xenobiotics are first activated to an acyl-CoA by the mitochondrial xenobiotic/medium-chain fatty acid: CoA ligases (ACSMs) and subsequently conjugated to glycine by glycine N-acyltransferase (GLYAT).	Glycine	155-162	glycine-N-acyltransferase	Homo sapiens	166-191
29948332-2	2018	Xenobiotics are first activated to an acyl-CoA by the mitochondrial xenobiotic/medium-chain fatty acid: CoA ligases (ACSMs) and subsequently conjugated to glycine by glycine N-acyltransferase (GLYAT).	Glycine	155-162	glycine-N-acyltransferase	Homo sapiens	193-198
30248338-6	2018	Moreover, increases in serum conjugated bile acids, including the VDR agonist glycine-lithocholic acid, were observed in NAFL patients.	Glycine	78-85	vitamin D receptor	Homo sapiens	66-69
10446221-2	1999	Several missense IGF2R mutations have been identified in human cancers, including the following amino acid substitutions occurring in the extracytoplasmic domain of the receptor: Cys-1262 --&gt; Ser, Gln-1445 --&gt; His, Gly-1449 --&gt; Val, Gly-1464 --&gt; Glu, and Ile-1572 --&gt; Thr.	Glycine	242-245	insulin like growth factor 2 receptor	Homo sapiens	17-22
29405790-7	2018	Thus, a peptide, GPLGLAGDDYCDGFYACYMDV-NH2, which consists of AHNP and an MMP-2 cleavable linker GPLGLAGDD, was first designed, followed by conjugation with DOX via a glycine residue at the N-terminus to form a novel DOX-peptide conjugate MAHNP-DOX.	Glycine	167-174	matrix metallopeptidase 2	Mus musculus	74-79
10446221-5	1999	Gly-1449 --&gt; Val and Cys-1262 --&gt; Ser each showed 30-60% decreases in the number of sites available to bind both (125)I-IGF-II and (125)I-PMP-BSA.	Glycine	0-3	insulin like growth factor 2	Homo sapiens	126-132
30011082-0	2018	Binding of p67phox to Nox2 is stabilized by disulfide bonds between cysteines in the 369 Cys-Gly-Cys371 triad in Nox2 and in p67phox.	Glycine	93-96	cytochrome b-245 beta chain	Homo sapiens	22-26
30152697-3	2018	The peptide sequence Arg-Gly-Asp (RGD), which is present in a number of endogenous integrin ligands like fibronectin, vitronectin, and related proteins of the extracellular matrix (ECM), has been extensively used as a targeting vector for therapeutic as well as diagnostic purposes, and cilengitide, a cyclic RGD peptide, has entered clinical trials for the treatment of various cancers.	Glycine	25-28	vitronectin	Homo sapiens	118-129
30011082-0	2018	Binding of p67phox to Nox2 is stabilized by disulfide bonds between cysteines in the 369 Cys-Gly-Cys371 triad in Nox2 and in p67phox.	Glycine	93-96	cytochrome b-245 beta chain	Homo sapiens	113-117
29871716-13	2018	The species-specific regulation of CSAD reflects the differential preference of bile acid conjugation to glycine and taurine in humans and mice, respectively.	Glycine	105-112	cysteine sulfinic acid decarboxylase	Homo sapiens	35-39
10444566-0	1999	Glycine-extended gastrin regulates HEK cell growth.	Glycine	0-7	gastrin	Homo sapiens	17-24
30367038-1	2018	The conversion of serine and glycine that is accomplished by serine hydroxymethyltransferase 2 (SHMT2) in mitochondria is significantly upregulated in various cancers to support cancer cell proliferation.	Glycine	29-36	serine hydroxymethyltransferase 2	Homo sapiens	61-94
30367038-1	2018	The conversion of serine and glycine that is accomplished by serine hydroxymethyltransferase 2 (SHMT2) in mitochondria is significantly upregulated in various cancers to support cancer cell proliferation.	Glycine	29-36	serine hydroxymethyltransferase 2	Homo sapiens	96-101
10615243-5	1999	Gastrimmune is a gastrin immunogen in which the amino terminus of the gastrin-17 molecule is linked to diphtheria toxoid and induces antibodies which neutralise the amidated and glycine-extended forms of gastrin-17.	Glycine	178-185	gastrin	Homo sapiens	17-24
31819726-0	2018	Transcriptional enhancement of a bacterial choline oxidase A gene by an HSP terminator improves the glycine betaine production and salinity stress tolerance of Eucalyptus camaldulensis trees.	Glycine	100-107	heat shock protein	Arabidopsis thaliana	72-75
30217234-7	2018	RESULTS: Ion channels exhibited cut-off effects associated with hydrocarbon molar water solubility in the following order of decreasing solubility: Nav1.2   Nav1.4   TRESK   TREK-1 &gt; GABAA &gt;&gt; glycine.	Glycine	201-208	sodium voltage-gated channel alpha subunit 2	Homo sapiens	148-154
29510000-7	2018	The variant allele of BRCA1 Cys39Gly increased breast cancer risk (Gly/Cys versus Cys/Cys, OR: 12.2, 95%CI: 1.53; 98.1), and carriers of the variant allele of CYP17A1 -34T&gt;C had reduced risk (CT+CC versus TT, OR: 0.44, 95%CI: 0.21; 0.93).	Glycine	33-36	BRCA1 DNA repair associated	Homo sapiens	22-27
30089600-5	2018	This mutation, ALK G1128A, is located at the glycine loop (the P-loop) of the ALK tyrosine kinase domain.	Glycine	45-52	ALK receptor tyrosine kinase	Homo sapiens	15-18
30089600-5	2018	This mutation, ALK G1128A, is located at the glycine loop (the P-loop) of the ALK tyrosine kinase domain.	Glycine	45-52	ALK receptor tyrosine kinase	Homo sapiens	78-81
30154813-11	2018	Mutating the serine in BAM2 to a glycine resulted in an enzyme with a VMax similar to that of the wild type enzyme but with a 7.5-fold lower KM for soluble starch.	Glycine	33-40	beta-amylase 2	Arabidopsis thaliana	23-27
29921582-8	2018	Notably, we also found that K27me2 is increased and K36me1 decreased on H3.3(G34V), which suggests that Gly-34 mutations dysregulate Lys-27 and Lys-36 methylation in cis The fact that Rpp29 represses H3.3 chromatin assembly and sense and antisense RNA and promotes H3K9me3 and H3K27me3 suggests that Rpp29 regulates H3.3-mediated epigenetic mechanisms by processing a transcribed signal that recruits H3.3 to its incorporation sites.	Glycine	104-107	POP4 homolog, ribonuclease P/MRP subunit	Homo sapiens	184-189
29921582-8	2018	Notably, we also found that K27me2 is increased and K36me1 decreased on H3.3(G34V), which suggests that Gly-34 mutations dysregulate Lys-27 and Lys-36 methylation in cis The fact that Rpp29 represses H3.3 chromatin assembly and sense and antisense RNA and promotes H3K9me3 and H3K27me3 suggests that Rpp29 regulates H3.3-mediated epigenetic mechanisms by processing a transcribed signal that recruits H3.3 to its incorporation sites.	Glycine	104-107	POP4 homolog, ribonuclease P/MRP subunit	Homo sapiens	300-305
30091703-1	2018	D-aminoacyl-tRNA deacylase (DTD) acts on achiral glycine, in addition to D-amino acids, attached to tRNA.	Glycine	49-56	solute carrier family 26 member 2	Homo sapiens	0-26
29886732-4	2018	In vivo inhibition of GlyT1 was demonstrated for select compounds within this series by measuring the elevation of glycine in the cerebrospinal fluid (CSF) of rats after a single oral dose of 10 mg/kg.	Glycine	115-122	solute carrier family 6 member 9	Rattus norvegicus	22-27
29356040-8	2018	This signal transduction was initiated by competitive binding of CD147 with integrin beta1 that interrupted the interaction between the Arg-Gly-Asp motif of fibronectin and integrin beta1.	Glycine	140-143	integrin subunit beta 1	Homo sapiens	76-90
29356040-8	2018	This signal transduction was initiated by competitive binding of CD147 with integrin beta1 that interrupted the interaction between the Arg-Gly-Asp motif of fibronectin and integrin beta1.	Glycine	140-143	integrin subunit beta 1	Homo sapiens	173-187
29958424-2	2018	The first of these proteins is a pyridoxal 5"-phosphate (PLP)-dependent homodimeric enzyme, 5-aminolevulinate synthase (ALAS), that catalyzes the rate-limiting step in heme biosynthesis, the condensation of glycine with succinyl-CoA.	Glycine	207-214	aminolevulinic acid synthase 2, erythroid	Mus musculus	120-124
29695495-2	2018	Previous studies have shown that mammalian Mre11 is methylated at multiple arginines in its C-terminal Glycine-Arginine-Rich motif (GAR) by protein arginine methyltransferase PRMT1.	Glycine	103-110	protein arginine methyltransferase 1	Homo sapiens	175-180
29851957-1	2018	The KRAS oncogene, present in over 90% of pancreatic ductal adenocarcinomas, is most frequently the result of one of three gain-of-function substitution mutations of codon 12 glycine.	Glycine	175-182	KRAS proto-oncogene, GTPase	Homo sapiens	4-8
29356901-0	2018	Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis.	Glycine	0-7	interleukin 10	Homo sapiens	47-52
29356901-7	2018	However, the mRNA levels of adiponectin and interleukin-10 (IL-10), two adipose-derived adipocytokines with anti-inflammatory effects, were greatly enhanced (P &lt; 0.05) by 2 mmol/L glycine.	Glycine	183-190	interleukin 10	Homo sapiens	44-58
29356901-7	2018	However, the mRNA levels of adiponectin and interleukin-10 (IL-10), two adipose-derived adipocytokines with anti-inflammatory effects, were greatly enhanced (P &lt; 0.05) by 2 mmol/L glycine.	Glycine	183-190	interleukin 10	Homo sapiens	60-65
29356901-11	2018	In conclusion, glycine exposure enhanced the mRNA levels of adipose-derived adiponectin and IL-10 without affecting adipogenesis and lipolysis in 3T3-L1 adipocytes.	Glycine	15-22	interleukin 10	Homo sapiens	92-97
29471495-4	2018	Protein arginine methyltransferase (PRMT) 1, PRMT3 and PRMT6 all methylate TOP3B in vitro at its C-terminal arginine (R) and glycine (G)-rich motif.	Glycine	125-132	protein arginine methyltransferase 1	Homo sapiens	0-43
29850613-8	2018	Glycine or CGP53353 treatment significantly reduced the increase of LDH release, MDA production, PKCbeta2 activation, and Cyt-C expression and the decrease of cell viability, SOD activity, MMP, Mfn-2 expression, and LC-3II/LC-3I ratio induced by HG and H/R stimulation.	Glycine	0-7	mitofusin 2	Rattus norvegicus	194-199
29196110-6	2018	With regards to the cleavage behavior of neprilysin, a strong preference for Gly at P1 was found, while Gly, Ala and Val were well accepted at P1" upon cleavage of tropoelastin and skin elastin.	Glycine	104-107	elastin	Homo sapiens	164-176
29352967-3	2018	9S-DOX-allene oxide synthase (AOS) oxidized the Gly, Ile, and Trp derivatives at C-9, which suggests that these conjugates enter the substrate recognition site with the omega end in analogy with fatty acids bound to cyclooxygenases and coral 8R-lipoxygenase (8R-LOX).	Glycine	48-51	complement C9	Homo sapiens	81-84
29352967-4	2018	In contrast, 7,8-diol synthases (7,8-LDS), 5,8-LDS, and 8R-DOX-AOS oxidized the Gly conjugates in most case only to small amounts of metabolites, but with retention of hydrogen abstraction at C-8 and relatively minor hydrogen abstraction at C-11.	Glycine	80-83	RNA polymerase III subunit K	Homo sapiens	241-245
30566931-9	2018	In reactome pathway analyses, Spp1 was enriched in toll-like receptor signalling, and Dmgdh was enriched in glycine, serine and threonine metabolic pathways.	Glycine	108-115	dimethylglycine dehydrogenase	Rattus norvegicus	86-91
28982678-9	2017	Molecular dynamics (MD) simulations showed that the hydrophobic core, which triggers SNARE complex formation, is compromised due to the glycine-to-tryptophan substitution in both GOSR2 and Bos1.	Glycine	136-143	golgi SNAP receptor complex member 2	Homo sapiens	179-184
28982678-9	2017	Molecular dynamics (MD) simulations showed that the hydrophobic core, which triggers SNARE complex formation, is compromised due to the glycine-to-tryptophan substitution in both GOSR2 and Bos1.	Glycine	136-143	golgi SNAP receptor complex member 2	Homo sapiens	189-193
29753073-6	2018	Glycine transporter-1 inhibitor blocked the antioxidative effect of glycine by reducing the intracellular GSH content, and glycine receptor inhibitor reversed the glycine antioxidative effect by blocking p22phox.	Glycine	68-75	solute carrier family 6 member 9	Rattus norvegicus	0-21
29753073-7	2018	Collectively, our findings reveal a mechanism by which glycine protects diabetic beta-cells against damage caused by oxidative stress by increasing glycine transporter-1-mediated synthesis of GSH and by reducing glycine receptor-mediated ROS production.	Glycine	55-62	solute carrier family 6 member 9	Rattus norvegicus	148-169
30196019-0	2018	Glycine mitigates renal oxidative stress by suppressing Nox4 expression in rats with streptozotocin-induced diabetes.	Glycine	0-7	NADPH oxidase 4	Rattus norvegicus	56-60
30196019-7	2018	Renal levels of the Nox4 mRNA and protein, a major source of renal oxidative stress, were suppressed by the treatment with glycine.	Glycine	123-130	NADPH oxidase 4	Rattus norvegicus	20-24
30196019-9	2018	Our results strongly suggest that the protective effect of glycine on renal oxidative stress and structural damage may be linked to enhancement of GSH synthesis and suppression of renal Nox4 expression in diabetic rats.	Glycine	59-66	NADPH oxidase 4	Rattus norvegicus	186-190
30037884-8	2018	Screening potential substrates in Ine expressing Xenopus oocytes revealed very little response to carcinine and beta-Ala but increased conductance with glycine.	Glycine	152-159	inebriated	Drosophila melanogaster	34-37
29657074-6	2018	Similarly, G35A, A49G and A64G transitions were identified in the PRM2 gene which resulted in altered amino acid sequences from arginine (R) to glutamine (Q), from arginine (R) to glycine (G) and from arginine (R) to glycine (G), respectively.	Glycine	180-187	protamine 2	Bos taurus	66-70
29657074-6	2018	Similarly, G35A, A49G and A64G transitions were identified in the PRM2 gene which resulted in altered amino acid sequences from arginine (R) to glutamine (Q), from arginine (R) to glycine (G) and from arginine (R) to glycine (G), respectively.	Glycine	217-224	protamine 2	Bos taurus	66-70
29661936-8	2018	Substitutions in the Cat domain affecting substrate specificity revealed that residues Phe-634, His-661, and Gly-671 in the S1-binding pocket of this domain are important for Ssy5 catalytic function.	Glycine	109-112	Ssy5p	Saccharomyces cerevisiae S288C	175-179
29511087-8	2018	The alanine-scanning experiments revealed that residues Tyr-34, Gln-38, Gly-39, and Leu-45 (in the AB loop) and Pro-153 (in the D-helix) had specific roles in activating OSMR but not LIFR signaling, whereas Leu-40 and Cys-49 (in the AB loop), and Phe-160 and Lys-163 (in the D-helix) were required for activation of both receptors.	Glycine	72-75	oncostatin M receptor	Homo sapiens	170-174
29116606-8	2018	Sanger sequencing showed a homozygous missense mutation in SLC2A2 (exon 7, c.952G &gt; A), causing glycine to arginine substitution; both parents were heterozygous carriers.	Glycine	99-106	solute carrier family 2 member 2	Homo sapiens	59-65
29470850-5	2018	RESULTS: A novel glycine-to-aspartic acid substitution (G310D) in IGF1R was identified, which associated with T2D in a sex-specific manner (Psex interaction = 0.02).	Glycine	17-24	insulin like growth factor 1 receptor	Homo sapiens	66-71
29992271-6	2018	By solution-state nuclear magnetic resonance, one of these CHAMP peptides was shown to bind primarily the integrin beta1 TM domain, which itself has a Gly-X3-Gly motif.	Glycine	151-154	integrin subunit beta 1	Homo sapiens	106-120
29992271-6	2018	By solution-state nuclear magnetic resonance, one of these CHAMP peptides was shown to bind primarily the integrin beta1 TM domain, which itself has a Gly-X3-Gly motif.	Glycine	158-161	integrin subunit beta 1	Homo sapiens	106-120
29674746-6	2018	Mechanisms whereby tumours sustained HT under CD44-knockdown conditions include upregulation of PHGDH, PSAT1 and PSPH that drove glycolysis-dependent activation of serine/glycine-cleavage systems to provide one-methyl group for HT synthesis.	Glycine	171-178	CD44 molecule (Indian blood group)	Homo sapiens	46-50
29611532-8	2018	Homology modelling and molecular docking analysis of ST14 with wild-type TMEFF1 protein was performed which revealed that glycine at position 439 is crucial for maintaining normal structural confirmation and interaction with the EGF domain of TMEFF1 protein.	Glycine	122-129	transmembrane protein with EGF like and two follistatin like domains 1	Homo sapiens	73-79
29611532-8	2018	Homology modelling and molecular docking analysis of ST14 with wild-type TMEFF1 protein was performed which revealed that glycine at position 439 is crucial for maintaining normal structural confirmation and interaction with the EGF domain of TMEFF1 protein.	Glycine	122-129	transmembrane protein with EGF like and two follistatin like domains 1	Homo sapiens	243-249
29193371-3	2018	Gly-Arg-Rich regions (RGG-boxes) within FET proteins are targets for methylation by Protein-Arginine-Methyl-Transferase-1 (PRMT1) and substrate capture is thought to involve electrostatic attraction between positively charged polyRGG substrates and negatively charged surface channels of PRMT1.	Glycine	0-3	protein arginine methyltransferase 1	Homo sapiens	84-121
29193371-3	2018	Gly-Arg-Rich regions (RGG-boxes) within FET proteins are targets for methylation by Protein-Arginine-Methyl-Transferase-1 (PRMT1) and substrate capture is thought to involve electrostatic attraction between positively charged polyRGG substrates and negatively charged surface channels of PRMT1.	Glycine	0-3	protein arginine methyltransferase 1	Homo sapiens	123-128
29193371-3	2018	Gly-Arg-Rich regions (RGG-boxes) within FET proteins are targets for methylation by Protein-Arginine-Methyl-Transferase-1 (PRMT1) and substrate capture is thought to involve electrostatic attraction between positively charged polyRGG substrates and negatively charged surface channels of PRMT1.	Glycine	0-3	protein arginine methyltransferase 1	Homo sapiens	288-293
29325204-4	2018	After the cleavage of the Gly-Phe-Leu-Gly (GFLG) sequence by pericellular overexpressed cathepsin B, CTGP@DOX is dissociated and transformed from spherical nanoparticles to nanofibers due to the hydrophilic-hydrophobic conversion and hydrogen bonding interactions.	Glycine	26-29	cathepsin B	Homo sapiens	88-99
28674275-7	2018	The two glycines in F. kawamurai and G. rugosa, and the lysine deleted in one P. nigromaculatus albino, were highly conserved in vertebrates, which suggested that they were situated in regions of critical importance to tyrosinase function.	Glycine	8-16	tyrosinase	Homo sapiens	219-229
29255089-3	2018	Here, we report that substitution of Gly-4941 with Asp or Lys results in functional channels as indicated by caffeine-induced Ca2+ release response in HEK293 cells, whereas a low response of the corresponding Gly-4934 variants suggested loss of function.	Glycine	37-40	carbonic anhydrase 2	Homo sapiens	126-129
29319298-7	2018	We demonstrate that replacing Leu with Gly (L150G) in HsCalu1 enables the protein to adopt a structural fold even in the Ca2+ free form, similar to CeCalu, leading to ligand compensation (adoption of structure in the absence of Ca2+).	Glycine	39-42	carbonic anhydrase 2	Homo sapiens	121-124
29319298-7	2018	We demonstrate that replacing Leu with Gly (L150G) in HsCalu1 enables the protein to adopt a structural fold even in the Ca2+ free form, similar to CeCalu, leading to ligand compensation (adoption of structure in the absence of Ca2+).	Glycine	39-42	carbonic anhydrase 2	Homo sapiens	228-231
29283194-6	2018	When Arg-Gly-Asp-AAP (AAP-RGD) peptides are attached to surface bound CB[8]/MV2+ complexes, cells adhere and can be released upon irradiation.	Glycine	9-12	serpin family F member 2	Homo sapiens	17-20
29283194-6	2018	When Arg-Gly-Asp-AAP (AAP-RGD) peptides are attached to surface bound CB[8]/MV2+ complexes, cells adhere and can be released upon irradiation.	Glycine	9-12	serpin family F member 2	Homo sapiens	22-25
29128679-7	2018	In this case, we identified a de novo mutation (c.4423G &gt; A; glycine [Gly]1475 arginine [Arg]) classified as heterozygous missense located in the inactivation gate section of the SCN8A (voltage-gated sodium-channel type VIII alpha subunit) gene.	Glycine	64-71	sodium voltage-gated channel alpha subunit 8	Homo sapiens	182-241
29128679-7	2018	In this case, we identified a de novo mutation (c.4423G &gt; A; glycine [Gly]1475 arginine [Arg]) classified as heterozygous missense located in the inactivation gate section of the SCN8A (voltage-gated sodium-channel type VIII alpha subunit) gene.	Glycine	73-76	sodium voltage-gated channel alpha subunit 8	Homo sapiens	182-241
28978648-5	2017	Small angle X-ray scattering analysis indicated that STAT1ND associates with the N-terminal domain of STAT2 (STAT2ND) with the help of a Gly-rich linker.	Glycine	137-140	signal transducer and activator of transcription 1	Homo sapiens	53-60
28978648-5	2017	Small angle X-ray scattering analysis indicated that STAT1ND associates with the N-terminal domain of STAT2 (STAT2ND) with the help of a Gly-rich linker.	Glycine	137-140	signal transducer and activator of transcription 2	Homo sapiens	102-107
28978648-5	2017	Small angle X-ray scattering analysis indicated that STAT1ND associates with the N-terminal domain of STAT2 (STAT2ND) with the help of a Gly-rich linker.	Glycine	137-140	signal transducer and activator of transcription 2	Homo sapiens	109-116
29149036-1	2017	The gene encoding the high glycine/tyrosine keratin-associated protein 20-2 (KAP20-2) gene has been described in humans, but has not been identified in any livestock species.	Glycine	27-34	keratin associated protein 20-2	Homo sapiens	44-75
29149036-1	2017	The gene encoding the high glycine/tyrosine keratin-associated protein 20-2 (KAP20-2) gene has been described in humans, but has not been identified in any livestock species.	Glycine	27-34	keratin associated protein 20-2	Homo sapiens	77-84
10615243-5	1999	Gastrimmune is a gastrin immunogen in which the amino terminus of the gastrin-17 molecule is linked to diphtheria toxoid and induces antibodies which neutralise the amidated and glycine-extended forms of gastrin-17.	Glycine	178-185	gastrin	Homo sapiens	70-77
28919039-5	2017	Both cross-reactivities were abolished by the removal of the C-terminal Gly in the ABP"s proximal Ub, yielding the specific OTULIN probe UbG76Dha-UbDeltaG76 (OTULIN ABPDeltaG76).	Glycine	72-75	OTU deubiquitinase with linear linkage specificity	Homo sapiens	124-130
10615243-5	1999	Gastrimmune is a gastrin immunogen in which the amino terminus of the gastrin-17 molecule is linked to diphtheria toxoid and induces antibodies which neutralise the amidated and glycine-extended forms of gastrin-17.	Glycine	178-185	gastrin	Homo sapiens	70-77
28919039-5	2017	Both cross-reactivities were abolished by the removal of the C-terminal Gly in the ABP"s proximal Ub, yielding the specific OTULIN probe UbG76Dha-UbDeltaG76 (OTULIN ABPDeltaG76).	Glycine	72-75	OTU deubiquitinase with linear linkage specificity	Homo sapiens	158-164
28212872-6	2018	RESULTS: The percentages of the gp78 gene polymorphisms of Arg/Arg, Arg/Gly and Gly/Gly at the 145 locus of the study subjects in the observation group were 12.3%, 43.2% and 44.5%, respectively, while those in the control group were 74.3%, 11.2% and 14.5%, respectively, and there were significant differences between both groups.	Glycine	72-75	autocrine motility factor receptor	Homo sapiens	32-36
28212872-6	2018	RESULTS: The percentages of the gp78 gene polymorphisms of Arg/Arg, Arg/Gly and Gly/Gly at the 145 locus of the study subjects in the observation group were 12.3%, 43.2% and 44.5%, respectively, while those in the control group were 74.3%, 11.2% and 14.5%, respectively, and there were significant differences between both groups.	Glycine	80-83	autocrine motility factor receptor	Homo sapiens	32-36
28850877-6	2017	Within the data sets of peptides predicted to lie in coil regions, both hPAD2 and hPAD4 appear to favor citrullination of glycine-containing motifs, while distinct hydrophobic motifs were identified for hPAD2 citrullination sites predicted to reside within alpha-helical and beta-sheet regions.	Glycine	122-129	peptidyl arginine deiminase 2	Homo sapiens	72-77
10463479-7	1999	All of the tumors that showed H-ras alteration had G-to-T transversion mutations in the second base of codon 12 (glycine --&gt; valine).	Glycine	113-120	HRas proto-oncogene, GTPase	Homo sapiens	30-35
28956357-5	2017	First, glycine was repeatedly selected at CRP position 184 for its unique ability to provide wild type-level transcriptional activation activity.	Glycine	7-14	catabolite gene activator protein	Escherichia coli	42-45
28212872-6	2018	RESULTS: The percentages of the gp78 gene polymorphisms of Arg/Arg, Arg/Gly and Gly/Gly at the 145 locus of the study subjects in the observation group were 12.3%, 43.2% and 44.5%, respectively, while those in the control group were 74.3%, 11.2% and 14.5%, respectively, and there were significant differences between both groups.	Glycine	80-83	autocrine motility factor receptor	Homo sapiens	32-36
29483823-6	2018	The serum metabonomics study showed that the LDLR-/- ,PSGL-1-/- mice had higher levels of HDL, valine, acetate, pyruvate, choline, PC, GPC and glycine, and lower levels of LDL+VLDL and lactate at the early stage of atherosclerosis, while lactate, citrate and glutamine showed statistical significance at the late stage of atherosclerosis.	Glycine	143-150	low density lipoprotein receptor	Mus musculus	45-49
28050793-6	2018	On the other hand, synaptophysin levels were decreased in striatum at 30 min and in cerebral cortex at 24 h after GLY injection.	Glycine	114-117	synaptophysin	Rattus norvegicus	19-32
28627122-11	2017	These results suggest that biotinylated peptides, especially BP21, can specifically and markedly inhibit anaphylactic reactions in vivo and that this involves direct interaction of its Tyr-Lys-Asp-Gly region with PAF.	Glycine	197-200	PCNA clamp associated factor	Rattus norvegicus	213-216
10377242-2	1999	C-terminal amidation entails sequential action by peptidylglycine mono-oxygenase (PAM, EC 1.14.17.3) and peptidylamidoglycolate lyase (PGL, EC 4.3.2.5), with the mono-oxygenase catalysing conversion of a glycine-extended pro-peptide into the corresponding alpha-hydroxyglycine derivative, which is then converted by the lyase into amidated peptide plus glyoxylate.	Glycine	58-65	peptidylglycine alpha-amidating monooxygenase L homeolog	Xenopus laevis	82-85
29101280-0	2018	Arabidopsis Novel Glycine-Rich Plasma Membrane PSS1 Protein Enhances Disease Resistance in Transgenic Soybean Plants.	Glycine	18-25	phosphatidyl serine synthase family protein	Arabidopsis thaliana	47-51
10379516-2	1999	Patients were assessed for TD severity using the Abnormal Involuntary Movement Scale (AIMS) and were subsequently genotyped for the MscI polymorphism that identifies a serine to glycine substitution in DRD3.	Glycine	178-185	dopamine receptor D3	Homo sapiens	202-206
28888841-1	2017	The neuron-specific K-Cl cotransporter KCC2 maintains the low intracellular chloride concentration required for the fast hyperpolarizing responses of the inhibitory neurotransmitters gamma-aminobutyric acid (GABA) and glycine.	Glycine	218-225	solute carrier family 12 member 5	Homo sapiens	39-43
28334903-6	2017	The Arg-Gly-Gly repeats within the low-complexity region are required for binding to the RNA motif exposed by m6A methylation.	Glycine	8-11	glycoprotein M6A	Homo sapiens	110-113
28334903-6	2017	The Arg-Gly-Gly repeats within the low-complexity region are required for binding to the RNA motif exposed by m6A methylation.	Glycine	12-15	glycoprotein M6A	Homo sapiens	110-113
28363510-0	2017	X-Linked Cobalamin Disorder (HCFC1) Mimicking Nonketotic Hyperglycinemia With Increased Both Cerebrospinal Fluid Glycine and Methylmalonic Acid.	Glycine	113-120	host cell factor C1	Homo sapiens	29-34
28363510-11	2017	CONCLUSIONS: This boy had X-linked cobalamin deficiency (HCFC1) with increased cerebrospinal fluid glycine and methylmalonic acid and increased cerebrospinal fluid to plasma glycine ratio suggesting a brain hyperglycinemia.	Glycine	99-106	host cell factor C1	Homo sapiens	57-62
10379516-4	1999	The glycine allele of DRD3 was found to be associated with typical neuroleptic-induced TD (F[2,95] = 8.25, p &lt; .0005).	Glycine	4-11	dopamine receptor D3	Homo sapiens	22-26
28363510-11	2017	CONCLUSIONS: This boy had X-linked cobalamin deficiency (HCFC1) with increased cerebrospinal fluid glycine and methylmalonic acid and increased cerebrospinal fluid to plasma glycine ratio suggesting a brain hyperglycinemia.	Glycine	174-181	host cell factor C1	Homo sapiens	57-62
28363510-12	2017	Putative binding sites for HCFC1 and its binding partner THAP11 were identified near genes of the glycine cleavage enzyme, providing a potential mechanistic link between HCFC1 mutations and increased glycine.	Glycine	98-105	host cell factor C1	Homo sapiens	27-32
10379516-5	1999	Higher mean AIMS scores were found in patients homozygous for the glycine variant of the DRD3 gene, as compared to both heterozygous and serine homozygous patients.	Glycine	66-73	dopamine receptor D3	Homo sapiens	89-93
28363510-12	2017	Putative binding sites for HCFC1 and its binding partner THAP11 were identified near genes of the glycine cleavage enzyme, providing a potential mechanistic link between HCFC1 mutations and increased glycine.	Glycine	98-105	host cell factor C1	Homo sapiens	170-175
28363510-12	2017	Putative binding sites for HCFC1 and its binding partner THAP11 were identified near genes of the glycine cleavage enzyme, providing a potential mechanistic link between HCFC1 mutations and increased glycine.	Glycine	200-207	host cell factor C1	Homo sapiens	27-32
10418163-0	1999	Low expression of the ClC-2 chloride channel during postnatal development: a mechanism for the paradoxical depolarizing action of GABA and glycine in the hippocampus.	Glycine	139-146	chloride voltage-gated channel 2 S homeolog	Xenopus laevis	22-27
28363510-12	2017	Putative binding sites for HCFC1 and its binding partner THAP11 were identified near genes of the glycine cleavage enzyme, providing a potential mechanistic link between HCFC1 mutations and increased glycine.	Glycine	200-207	host cell factor C1	Homo sapiens	170-175
28877491-10	2017	These results demonstrate that only the amphiphile that thinned Ld lipid domains increased beta1-integrin-Arg-Gly-Asp-peptide affinity and valency, thus implicating Ld domains in modulation of integrin adhesion, nascent adhesion formation, and cell migration.	Glycine	110-113	integrin subunit beta 1	Homo sapiens	91-105
10418163-5	1999	We have tested the hypothesis that in the developing hippocampus, a differential expression or regulation of ClC-2 channels may contribute to the depolarizing action of GABA and glycine.	Glycine	178-185	chloride voltage-gated channel 2 S homeolog	Xenopus laevis	109-114
28516893-11	2017	Since PEG is a synthetic polymer devoid of cell attachment sites, we could overcome this limitation by tethering Arg-Gly-Asp-Ser (RGDS) peptide to the PEG hydrogel microspheres; upon RGDS tethering, we observed uniform cell dispersion.	Glycine	117-120	ral guanine nucleotide dissociation stimulator	Mus musculus	130-134
28516893-11	2017	Since PEG is a synthetic polymer devoid of cell attachment sites, we could overcome this limitation by tethering Arg-Gly-Asp-Ser (RGDS) peptide to the PEG hydrogel microspheres; upon RGDS tethering, we observed uniform cell dispersion.	Glycine	117-120	ral guanine nucleotide dissociation stimulator	Mus musculus	183-187
28372155-3	2017	The PPy-GOx/PPy-Cl bilayer biosensor was effective in rejecting 98% of ascorbic acid and 100% of glycine, glutamic acid and uric acid.	Glycine	97-104	hydroxyacid oxidase 1	Homo sapiens	8-11
10418163-9	1999	Low expression of the full-length ClC-2 channel, could alter chloride homeostasis, lead to accumulation of [Cl-]i and thereby contribute to the depolarizing action of GABA and glycine during early development.	Glycine	176-183	chloride voltage-gated channel 2 S homeolog	Xenopus laevis	34-39
10364453-7	1999	Epitope tagged human MPSK was found to be acylated by myristic acid at glycine residue 2 and by palmitic acid at cysteines 6 and/or 8.	Glycine	71-78	serine/threonine kinase 16	Homo sapiens	21-25
28570922-10	2017	After sequential amino acid substitution, we found the binding capacity of P14-2 was completely lost by the substitution of cysteine (C) 132 and significantly decreased by the substitution of tryptophan (W) 136, lysine (K) 141, or glycine (G) 142, but still at a high level.	Glycine	231-238	ribonuclease P/MRP subunit p14	Homo sapiens	75-78
28498836-8	2017	In the individuals with a COL1A1 mutation, 70% (7/10) of those with a glycine substitution located C-terminal of p.Gly305 exhibited DGI in both dentitions while no individual (0/7) with a mutation N-terminal of this point exhibited DGI in either dentition (p = 0.01).	Glycine	70-77	collagen type I alpha 1 chain	Homo sapiens	26-32
10328770-2	1999	Aminoacetone, an intermediate in the metabolism of threonine and glycine, has been proposed to be an endogenous substrate for semicarbazide-sensitive amine oxidase (SSAO).	Glycine	65-72	amine oxidase copper containing 2	Homo sapiens	126-163
29871349-2	2017	The SLC26A4 mutations were analyzed by direct sequencing.Result:A novel missense mutation(347G&gt;A) of SLC26A4 gene was found in a male patient,which led to a substitution of codon 116 from glycine to asparagic acid.	Glycine	191-198	solute carrier family 26 member 4	Homo sapiens	4-11
29871349-2	2017	The SLC26A4 mutations were analyzed by direct sequencing.Result:A novel missense mutation(347G&gt;A) of SLC26A4 gene was found in a male patient,which led to a substitution of codon 116 from glycine to asparagic acid.	Glycine	191-198	solute carrier family 26 member 4	Homo sapiens	104-111
28489663-2	2017	In this work, we compare the effects of two different species derived from synthetic Abeta1-42 and prepared without HFIP (Abeta) or using HFIP (Abeta/HFIP) on the glycine-activated chloride current (IGly).	Glycine	163-170	amyloid beta precursor protein	Rattus norvegicus	144-154
28489663-6	2017	Abeta or Abeta/HFIP was coapplied with glycine.	Glycine	39-46	amyloid beta precursor protein	Rattus norvegicus	9-19
28366003-8	2017	Three different PTMs: acetylation, methylation, and trimethylation were identified in human beta-MHC and the corresponding sites were localized to the N-terminal Gly, Lys34, and Lys129, respectively, by electron capture dissociation (ECD).	Glycine	162-165	major histocompatibility complex, class I, C	Homo sapiens	97-100
28713411-8	2017	Genetic and bioinformatics analyses of HKT1;4 of contrasting genotypes (Kharchia-65 and HD-2329) revealed deletions, transitions, and transversions resulting into altered structure, loss of conserved motifs (Ser-Gly-Gly-Gly and Gly-Arg) and function in salt-sensitive (HD-2329) genotype.	Glycine	212-215	cation transporter HKT1	Triticum aestivum	39-45
28713411-8	2017	Genetic and bioinformatics analyses of HKT1;4 of contrasting genotypes (Kharchia-65 and HD-2329) revealed deletions, transitions, and transversions resulting into altered structure, loss of conserved motifs (Ser-Gly-Gly-Gly and Gly-Arg) and function in salt-sensitive (HD-2329) genotype.	Glycine	216-219	cation transporter HKT1	Triticum aestivum	39-45
10328770-2	1999	Aminoacetone, an intermediate in the metabolism of threonine and glycine, has been proposed to be an endogenous substrate for semicarbazide-sensitive amine oxidase (SSAO).	Glycine	65-72	amine oxidase copper containing 2	Homo sapiens	165-169
10212188-4	1999	Rapid scanning stopped-flow experiments of murine erythroid 5-aminolevulinate synthase demonstrate that reaction with glycine plus succinyl-CoA results in a pre-steady-state burst of quinonoid intermediate formation.	Glycine	118-125	aminolevulinic acid synthase 1	Mus musculus	60-86
28713411-8	2017	Genetic and bioinformatics analyses of HKT1;4 of contrasting genotypes (Kharchia-65 and HD-2329) revealed deletions, transitions, and transversions resulting into altered structure, loss of conserved motifs (Ser-Gly-Gly-Gly and Gly-Arg) and function in salt-sensitive (HD-2329) genotype.	Glycine	216-219	cation transporter HKT1	Triticum aestivum	39-45
28713411-8	2017	Genetic and bioinformatics analyses of HKT1;4 of contrasting genotypes (Kharchia-65 and HD-2329) revealed deletions, transitions, and transversions resulting into altered structure, loss of conserved motifs (Ser-Gly-Gly-Gly and Gly-Arg) and function in salt-sensitive (HD-2329) genotype.	Glycine	216-219	cation transporter HKT1	Triticum aestivum	39-45
28029385-3	2017	Replacing a glycine residue within the cytosolic S4-S5 linker of the human TRPV6 protein, glycine 516, which is conserved in all TRP channel proteins, by a serine residue forces the channels into an open conformation thereby enhancing constitutive Ca2+ entry and preventing inactivation.	Glycine	12-19	transient receptor potential cation channel subfamily V member 6	Homo sapiens	75-80
28029385-3	2017	Replacing a glycine residue within the cytosolic S4-S5 linker of the human TRPV6 protein, glycine 516, which is conserved in all TRP channel proteins, by a serine residue forces the channels into an open conformation thereby enhancing constitutive Ca2+ entry and preventing inactivation.	Glycine	90-97	transient receptor potential cation channel subfamily V member 6	Homo sapiens	75-80
28004516-1	2017	Peptides with an exposed arginine-glycine-aspartate (Arg-Gly-Asp, RGD) sequence targeting the integrin alphaV beta3 play an important role in targeted anticancer drug delivery.	Glycine	34-41	integrin subunit alpha V	Homo sapiens	94-115
28004516-1	2017	Peptides with an exposed arginine-glycine-aspartate (Arg-Gly-Asp, RGD) sequence targeting the integrin alphaV beta3 play an important role in targeted anticancer drug delivery.	Glycine	57-60	integrin subunit alpha V	Homo sapiens	94-115
28514686-0	2017	Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein.	Glycine	0-7	endogenous retrovirus group K member 20	Homo sapiens	121-142
10212188-7	1999	Reaction of either glycine or 5-aminolevulinate with ALAS is slow (kf = 0.15 s-1) and approximates kcat.	Glycine	19-26	aminolevulinic acid synthase 1	Mus musculus	53-57
10209031-2	1999	Recently, mutation of glycine 2, cysteine 3, and lysines 7 and 9 was shown to block binding of Fyn to TCR zeta chain ITAMs, prompting the designation of these residues as an ITAM recognition motif (Gauen, L.K.T., M.E.	Glycine	22-29	FYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	95-98
28287329-1	2017	The cysteine protease ATG4B cleaves off one or more C-terminal residues of the inactive proform of proteins of the ortholog and paralog LC3 and GABARAP subfamilies of yeast Atg8 to expose a C-terminal glycine that is conjugated to phosphatidylethanolamine during autophagosome formation.	Glycine	201-208	autophagy related 4B, cysteine peptidase	Mus musculus	22-27
28259896-4	2017	In the folate cycle, glycine and serine fuel the mitochondrial enzymes SHMT2, MTHFD2 and ALDH1L2, which play critical roles in the cancer survival and proliferation presumably through purine production.	Glycine	21-28	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	78-84
10209031-2	1999	Recently, mutation of glycine 2, cysteine 3, and lysines 7 and 9 was shown to block binding of Fyn to TCR zeta chain ITAMs, prompting the designation of these residues as an ITAM recognition motif (Gauen, L.K.T., M.E.	Glycine	22-29	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	102-105
28110537-5	2017	We also confirmed this prediction by measuring dimeric cRGD (cyclic Arg-Gly-Asp) unbinding from integrin (alphavbeta3) using atomic force microscopy-based single-molecule force spectroscopy.	Glycine	72-75	integrin subunit alpha V	Homo sapiens	96-117
10187845-3	1999	In an heterologous CYC1 promoter the region needed for the glycine response of GCV2 (encoding the P-subunit of glycine decarboxylase) mediated repression that was relieved by glycine.	Glycine	59-66	cytochrome c isoform 1	Saccharomyces cerevisiae S288C	19-23
27211852-6	2017	Finally, a functional analysis indicated that the replacement of the 47th amino acid tryptophan (W47) with arginine (W47R) or glycine (W47G) led to reduced activity of alpha-galactosidase A in 293T cells.	Glycine	126-133	galactosidase alpha	Homo sapiens	168-189
28259896-4	2017	In the folate cycle, glycine and serine fuel the mitochondrial enzymes SHMT2, MTHFD2 and ALDH1L2, which play critical roles in the cancer survival and proliferation presumably through purine production.	Glycine	21-28	serine hydroxymethyltransferase 2	Homo sapiens	71-76
10187845-3	1999	In an heterologous CYC1 promoter the region needed for the glycine response of GCV2 (encoding the P-subunit of glycine decarboxylase) mediated repression that was relieved by glycine.	Glycine	59-66	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	79-83
28132660-10	2017	The amino acid shift degrades the S1/S2 glycine binding domain of the dominant modulatory GluN3B subunit of the NMDA receptor, which subsequently affects the permeability of the channel pore to calcium ions.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	90-96
28132660-11	2017	A decreased glycine affinity for the GluN3B subunit might cause impaired functional capability of the NMDA receptor and could be an important risk factor for the pathogenesis of psychotic disorders.	Glycine	12-19	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	37-43
10187845-3	1999	In an heterologous CYC1 promoter the region needed for the glycine response of GCV2 (encoding the P-subunit of glycine decarboxylase) mediated repression that was relieved by glycine.	Glycine	111-118	cytochrome c isoform 1	Saccharomyces cerevisiae S288C	19-23
10187845-3	1999	In an heterologous CYC1 promoter the region needed for the glycine response of GCV2 (encoding the P-subunit of glycine decarboxylase) mediated repression that was relieved by glycine.	Glycine	111-118	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	79-83
28179529-3	2017	Since only subsets of Phe/Gly motifs, particularly those within Nup62, Nup98, and Nup153, are recognized by transport receptors (karyopherins) when trafficking large molecular cargos through the NPC, the processing preferences of individual 2Apro predict RV genotype-specific targeting of NPC pathways and cargos.	Glycine	26-29	nucleoporin 62	Homo sapiens	64-69
28179529-3	2017	Since only subsets of Phe/Gly motifs, particularly those within Nup62, Nup98, and Nup153, are recognized by transport receptors (karyopherins) when trafficking large molecular cargos through the NPC, the processing preferences of individual 2Apro predict RV genotype-specific targeting of NPC pathways and cargos.	Glycine	26-29	nucleoporin 153	Homo sapiens	82-88
27762555-0	2017	Synthesis of Gly-psi[(Z)CF CH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic.	Glycine	13-16	prodynorphin	Mus musculus	100-114
10187845-7	1999	A protein was identified that bound to the glycine regulatory regions of GCV1 and GCV2 only if the CTTCTT motif was intact.	Glycine	43-50	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	82-86
10194377-1	1999	The sequence of granulocyte colony-stimulating factor (G-CSF) has been circularly permuted by introducing new chain termini into interhelical loops and by constraining the N- and C-terminal helices, either by direct linkage of the termini (L0) or by substitution of the amino-terminal 10-residue segment with a seven-residue linker composed of glycines and serines (L1).	Glycine	344-352	colony stimulating factor 3	Homo sapiens	16-53
27958698-3	2017	Specifically, peptide probes P1 and P2, which separately contain cysteine residues and tripeptides FGG (Phe-Gly-Gly), can be self-assembled onto the surface of the gold electrode and silver nanoparticles, respectively.	Glycine	108-111	crystallin gamma F, pseudogene	Homo sapiens	29-38
27958698-3	2017	Specifically, peptide probes P1 and P2, which separately contain cysteine residues and tripeptides FGG (Phe-Gly-Gly), can be self-assembled onto the surface of the gold electrode and silver nanoparticles, respectively.	Glycine	112-115	crystallin gamma F, pseudogene	Homo sapiens	29-38
27768593-1	2017	The newly discovered short (9 amino acid) non-RGD S-S bridged cyclic peptide ALOS-4 (H-cycl(Cys-Ser-Ser-Ala-Gly-Ser-Leu-Phe-Cys)-OH), which binds to integrin alphavbeta3 is investigated as peptide carrier for targeted drug delivery against human metastatic melanoma.	Glycine	108-111	integrin subunit alpha V	Homo sapiens	149-169
28828604-5	2017	The five additional glycine transporters ATB0,+, SNAT1, SNAT2, SNAT5, and LAT2 display broad amino acid specificity and have differential contributions to glial glycine transport.	Glycine	20-27	solute carrier family 1 member 5	Homo sapiens	41-45
28828604-5	2017	The five additional glycine transporters ATB0,+, SNAT1, SNAT2, SNAT5, and LAT2 display broad amino acid specificity and have differential contributions to glial glycine transport.	Glycine	20-27	solute carrier family 38 member 2	Homo sapiens	56-61
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	4-11	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	96-101
28828606-3	2017	The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc-1 or SNAT5/SN2.	Glycine	77-84	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	96-101
29256856-8	2017	The monomorphic yak KRTAP7-1 gene in particular, and highly conserved bovine, sheep and goat KRTAP7-1 genes in general, demonstrated its unique intrinsic structural property (e.g., &gt; 21% high glycine content) and primary functional importance in supporting the mechanical strength and shape of hair.	Glycine	195-202	keratin associated protein 7-1	Bos taurus	20-28
28942093-2	2017	The genetic analysis performed on our proband showed a novel homozygous mutation on codon 119 of lecithin-cholesterol acyltransferase gene that causes the substitution of glycine by aspartate.	Glycine	171-178	lecithin-cholesterol acyltransferase	Homo sapiens	97-133
27785568-2	2017	In the last years, mutations in four genes (NFU1, BOLA3, ISCA2 and IBA57) have been related to a new group of multiple mitochondrial dysfunction syndromes characterized by lactic acidosis, hyperglycinemia, multiple defects of the respiratory chain complexes, and impairment of four lipoic acid-dependent enzymes: alpha-ketoglutarate dehydrogenase complex, pyruvic dehydrogenase, branched-chain alpha-keto acid dehydrogenase complex and the H protein of the glycine cleavage system.	Glycine	194-201	iron-sulfur cluster assembly factor IBA57	Homo sapiens	67-72
27292783-7	2017	However, there are GlyR-independent mechanisms for glycine cytoprotection and other possible binding molecules of glycine are the NMDA receptor and receptors GlyT1 and GlyT2.	Glycine	114-121	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	168-173
28192309-1	2016	An oligopeptide: Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys-NH2, cleaved specifically by a matrix metalloproteinase 9 (MMP-9) at the Ser-Leu bond, was labeled on the epsilon-NH2 groups of lysine with donor (5, 6 TAMRA) and acceptor (HiLyte647) dye.	Glycine	21-24	matrix metallopeptidase 9	Homo sapiens	84-110
28192309-1	2016	An oligopeptide: Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys-NH2, cleaved specifically by a matrix metalloproteinase 9 (MMP-9) at the Ser-Leu bond, was labeled on the epsilon-NH2 groups of lysine with donor (5, 6 TAMRA) and acceptor (HiLyte647) dye.	Glycine	21-24	matrix metallopeptidase 9	Homo sapiens	112-117
28120589-8	2016	A de novo heterozygous deletion (c.272-274delGAG, p.G91del) in exon 4 of CRYBA1/A3 gene, leading to a deletion of Glycine at codon 91 was found.	Glycine	114-121	crystallin beta A1	Homo sapiens	73-79
27659424-8	2016	Elevations of hepatic mRNA levels for TNFalpha and chemokine (C-C motif) ligand 2 were also remarkably blunted in the glycine diet-fed mice.	Glycine	118-125	chemokine (C-C motif) ligand 2	Mus musculus	51-81
27790721-0	2016	A novel glycine substitution mutation in the COL7A1 gene in two Scottish families with dominant dystrophic epidermolysis bullosa presenting with milia on the hands and feet.	Glycine	8-15	collagen type VII alpha 1 chain	Homo sapiens	45-51
26899532-5	2016	hCA I, II and XII were generally better inhibited by sulfonamides incorporating longer scaffolds and Gly/Ala, whereas the best hCA IV inhibitors were homosulfanilamide derivatives, incorporating Phe moieties.	Glycine	101-104	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	0-17
27663971-3	2016	In the present study, we found that Abeta (1-42) in concentrations of 10 pM - 100nM enhanced desensitization of the glycine-activated current in isolated CA3 pyramidal neurons and also reversibly suppressed its peak amplitude during short (600ms) co-application with agonist.	Glycine	116-123	amyloid beta precursor protein	Rattus norvegicus	36-41
27663971-3	2016	In the present study, we found that Abeta (1-42) in concentrations of 10 pM - 100nM enhanced desensitization of the glycine-activated current in isolated CA3 pyramidal neurons and also reversibly suppressed its peak amplitude during short (600ms) co-application with agonist.	Glycine	116-123	carbonic anhydrase 3	Rattus norvegicus	154-157
27687590-3	2016	In this study, we constructed an Arg-Gly-Asp (RGD)-modified adenovirus, RGDAd-UPII-TK, that carries a suicide gene called HSV-TK that is driven by a human UPII promoter.	Glycine	37-40	uroplakin 2	Homo sapiens	78-82
27687590-3	2016	In this study, we constructed an Arg-Gly-Asp (RGD)-modified adenovirus, RGDAd-UPII-TK, that carries a suicide gene called HSV-TK that is driven by a human UPII promoter.	Glycine	37-40	uroplakin 2	Homo sapiens	155-159
27349874-1	2016	Most colorectal cancer (CRC) cell lines are identified to overexpress phosphoserine phosphatase (PSPH), which regulates the intracellular synthesis of serine and glycine, and supports tumor growth.	Glycine	162-169	phosphoserine phosphatase	Homo sapiens	97-101
26796363-6	2016	Another HLA-G new molecule was found in a woman from Hispaniola Island, Dominican Republic (Sto Domingo): it presented a silent change at alpha2 domain residue 107, Gly, GGA GGT and non-silent change at residue 178, Met Thr (with respect to HLA-G*01:01:01) which is close to class I molecule/clonotypic T cell receptor interaction sites.	Glycine	165-168	major histocompatibility complex, class I, G	Homo sapiens	8-13
26024288-2	2016	Peptidylglycine alpha-hydroxylating monooxygenase (PHM) is the PAM domain responsible for the copper-, ascorbate- and O2-dependent hydroxylation of a glycine-extended peptide.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	51-54
26024288-2	2016	Peptidylglycine alpha-hydroxylating monooxygenase (PHM) is the PAM domain responsible for the copper-, ascorbate- and O2-dependent hydroxylation of a glycine-extended peptide.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	63-66
26851528-3	2016	Resilin of Drosophila melanogaster contains Gly-rich repetitive motifs comprised of the amino acids, PSSSYGAPGGGNGGR, which confer elastic properties to resilin.	Glycine	44-47	resilin	Drosophila melanogaster	0-7
26851528-3	2016	Resilin of Drosophila melanogaster contains Gly-rich repetitive motifs comprised of the amino acids, PSSSYGAPGGGNGGR, which confer elastic properties to resilin.	Glycine	44-47	resilin	Drosophila melanogaster	153-160
27338790-5	2016	Crystallographic studies of the CRBN-DDB1-CC-885-GSPT1 complex reveal that GSPT1 binds to cereblon through a surface turn containing a glycine residue at a key position, interacting with both CC-885 and a "hotspot" on the cereblon surface.	Glycine	135-142	damage specific DNA binding protein 1	Homo sapiens	37-41
26812303-8	2016	We found that the mutation from arginine to glycine leads to the loss of 2 hydrogen bonds and to an unstable structure in the STAS domain of SLC26A6.	Glycine	44-51	solute carrier family 26 member 6	Homo sapiens	141-148
27106526-4	2016	Herein, utilizing the dual stimulus of hyperthermia and the intracellular redox environment, we devised a thermosensitive liposome (TSL) containing an Asparagine-Glycine-Arginine (NGR) peptide and reducible siRNA-CPPs for tumor-specific siRNA transfection (siRNA-CPPs/NGR-TSL), in which siRNA-CPPs were "caged" in NGR-TSL to overcome their limitations in vivo.	Glycine	162-169	reticulon 4 receptor	Homo sapiens	180-183
27059478-4	2016	By replacing the hydrophobic transmembrane domain of YND1 with three glycine-serine repeats, this protein was successfully expressed in a soluble form in Escherichia coli.	Glycine	69-76	apyrase	Saccharomyces cerevisiae S288C	53-57
27148439-8	2016	Meanwhile, one mutation of GGG   GGC (Gly   Gly) in codon288 of exon4 was detected in the proband.	Glycine	38-41	gamma-glutamylcyclotransferase	Homo sapiens	33-36
27148439-8	2016	Meanwhile, one mutation of GGG   GGC (Gly   Gly) in codon288 of exon4 was detected in the proband.	Glycine	44-47	gamma-glutamylcyclotransferase	Homo sapiens	33-36
26982589-1	2016	Peptidylglycine monooxygenase (PHM) is a dicopper enzyme that plays a vital role in the amidation of glycine-extended pro-peptides.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	31-34
26975021-10	2016	Moreover, AGL loss determines augmented levels of the serine-to-glycine enzyme serine hydroxymethyltransferase-2 (SHMT2), resulting in an increased glycine and purine ring of nucleotides synthesis, thus supporting cells proliferation.	Glycine	64-71	serine hydroxymethyltransferase 2	Homo sapiens	79-112
26975021-10	2016	Moreover, AGL loss determines augmented levels of the serine-to-glycine enzyme serine hydroxymethyltransferase-2 (SHMT2), resulting in an increased glycine and purine ring of nucleotides synthesis, thus supporting cells proliferation.	Glycine	64-71	serine hydroxymethyltransferase 2	Homo sapiens	114-119
26975021-10	2016	Moreover, AGL loss determines augmented levels of the serine-to-glycine enzyme serine hydroxymethyltransferase-2 (SHMT2), resulting in an increased glycine and purine ring of nucleotides synthesis, thus supporting cells proliferation.	Glycine	148-155	serine hydroxymethyltransferase 2	Homo sapiens	79-112
26975021-10	2016	Moreover, AGL loss determines augmented levels of the serine-to-glycine enzyme serine hydroxymethyltransferase-2 (SHMT2), resulting in an increased glycine and purine ring of nucleotides synthesis, thus supporting cells proliferation.	Glycine	148-155	serine hydroxymethyltransferase 2	Homo sapiens	114-119
26509826-3	2016	MATERIALS AND METHODS: A 20% packed volume of A1B RBC was treated with enzymes in 250 mM glycine buffer, pH 6.8.	Glycine	89-96	alpha-1-B glycoprotein	Homo sapiens	46-49
26364050-13	2016	The possibility to inhibit glycine transporter type-1 mediated glycine efflux by drugs more potently than glycine uptake might offer some therapeutic potential for the treatment of various neurodegenerative disorders of the retina.	Glycine	63-70	solute carrier family 6 member 9	Rattus norvegicus	27-53
26799485-0	2016	Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice.	Glycine	4-7	small nucleolar RNA, H/ACA box 73a	Mus musculus	31-34
29143559-3	2016	KCC2 levels are developmentally regulated, and a postnatal upregulation of KCC2 generates a low intracellular chloride concentration that allows the neurotransmitters gamma-aminobutyric acid (GABA) and glycine to exert inhibitory neurotransmission through its Cl- permeating channel.	Glycine	202-209	solute carrier family 12 member 5	Homo sapiens	0-4
29143559-3	2016	KCC2 levels are developmentally regulated, and a postnatal upregulation of KCC2 generates a low intracellular chloride concentration that allows the neurotransmitters gamma-aminobutyric acid (GABA) and glycine to exert inhibitory neurotransmission through its Cl- permeating channel.	Glycine	202-209	solute carrier family 12 member 5	Homo sapiens	75-79
26818177-3	2016	In humans, eRF3a/GSPT1 gene contains a stable GGC repeat encoding a repeat of glycine residues in eRF3a N-terminus.	Glycine	78-85	gamma-glutamylcyclotransferase	Homo sapiens	46-49
26395456-4	2015	Identified mutations in SPT1 are known to both reduce sphingolipid synthesis and generate catalytic promiscuity, incorporating alanine or glycine into the precursor sphingolipid to generate a deoxysphingoid base (DSB).	Glycine	138-145	Serine palmitoyltransferase subunit I	Drosophila melanogaster	24-28
26631477-5	2015	Using subunit-selective allosteric modulators of NMDA receptors (TCN-201, ifenprodil, CIQ, and DQP-1105), we provide evidence that receptors containing the GluN2B and GluN2D subunits mediate responses to exogenously applied NMDA and glycine, as well as synaptic NMDA receptor activation in the STN of rat brain slices.	Glycine	233-240	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	156-162
26200505-1	2015	Glycine transporters (GlyT), GlyT1 and GlyT2, are responsible for the termination of glycine-mediated synaptic activity through removal of neurotransmitter from synaptic cleft.	Glycine	85-92	solute carrier family 6 member 9	Rattus norvegicus	29-34
26021842-5	2015	RESULTS: One patient was found to have a new mutation in exon 6: g67.258,286 (G/A) heterozygote; (GGC/GAC; gly/asp).	Glycine	107-110	gamma-glutamylcyclotransferase	Homo sapiens	98-101
26283331-3	2015	We discovered that compared to the initial infection isolate, the strain recovered during asymptomatic carriage contained three single nucleotide polymorphisms, one of which was in a highly conserved region of a gene encoding a sensor kinase, liaS, resulting in an arginine-to-glycine amino acid replacement at position 135 of LiaS (LiaS(R135G)).	Glycine	277-295	lipoic acid synthetase	Mus musculus	243-247
26160850-0	2015	A Cys-Gly-Cys triad in the dehydrogenase region of Nox2 plays a key role in the interaction with p67phox.	Glycine	6-9	cytochrome b-245 beta chain	Homo sapiens	51-55
26160850-7	2015	Our results reveal an essential role for the Cys-Gly-Cys triad in Nox2 in binding p67(phox), seconded by an additional binding region, comprising residues C terminal to Cys-Gly-Cys.	Glycine	49-52	cytochrome b-245 beta chain	Homo sapiens	66-70
26378241-4	2015	LC3 is a substrate of the cysteine protease ATG4B (Autophagin-1), where cleavage generates a C-terminal glycine required for LC3 conjugation to lipids in autophagosomes.	Glycine	104-111	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	0-3
26378241-4	2015	LC3 is a substrate of the cysteine protease ATG4B (Autophagin-1), where cleavage generates a C-terminal glycine required for LC3 conjugation to lipids in autophagosomes.	Glycine	104-111	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	125-128
26388734-6	2015	With extrusion of chloride by KCC2, the Cl(-) reversal potential shifts and GABA and glycine responses become inhibitory.	Glycine	85-92	solute carrier family 12 member 5	Homo sapiens	30-34
28317937-5	2017	3D structure modelling of the 7 ankyrin-repeats coupled to functional analysis identified a surface epitope centered on one of the mutated residue, Gly-175, which is critical for controlling Rac1 binding and ubiquitylation.	Glycine	148-151	ankyrin 1	Homo sapiens	32-39
28317937-5	2017	3D structure modelling of the 7 ankyrin-repeats coupled to functional analysis identified a surface epitope centered on one of the mutated residue, Gly-175, which is critical for controlling Rac1 binding and ubiquitylation.	Glycine	148-151	Rac family small GTPase 1	Homo sapiens	191-195
28102596-3	2017	In addition, cEDS phenotype was reported in a small number of patients carrying the c.934C&gt;T mutation in COL1A1 that results in an uncommon substitution of a non-glycine residue in one Gly-Xaa-Yaa repeat of the pro-alpha1(I)-chain p.(Arg312Cys), which leads to disturbed collagen fibrillogenesis due to delayed removal of the type I procollagen N-propeptide.	Glycine	165-172	collagen type I alpha 1 chain	Homo sapiens	108-114
28102596-3	2017	In addition, cEDS phenotype was reported in a small number of patients carrying the c.934C&gt;T mutation in COL1A1 that results in an uncommon substitution of a non-glycine residue in one Gly-Xaa-Yaa repeat of the pro-alpha1(I)-chain p.(Arg312Cys), which leads to disturbed collagen fibrillogenesis due to delayed removal of the type I procollagen N-propeptide.	Glycine	188-191	collagen type I alpha 1 chain	Homo sapiens	108-114
28122815-4	2017	In this study, we show that mutating both Y699 and L701 to alanine, serine, aspartate, or glycine impairs human EAG1 channel function.	Glycine	90-97	potassium voltage-gated channel subfamily H member 1	Homo sapiens	112-116
27991616-8	2017	Furthermore, competitive endocytosis studies showed that the cellular uptake of APS-Lips was notably decreased in the presence of glycine, a typical substrate of ATB0,+, and was increased through adhesion to the cell membrane via transporter-substrate interactions.	Glycine	130-137	solute carrier family 1 member 5	Homo sapiens	162-166
28828604-4	2017	The unique glial glycine-selective transporter GlyT1 (SLC6) is the main regulator of synaptic glycine concentrations, assisted by the neuronal GlyT2.	Glycine	17-24	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	143-148
28828604-4	2017	The unique glial glycine-selective transporter GlyT1 (SLC6) is the main regulator of synaptic glycine concentrations, assisted by the neuronal GlyT2.	Glycine	94-101	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	143-148
28164502-7	2017	CONCLUSIONS: A glycine substitution specific to COL7A1, exon 110 c.8111G&gt;A, P.Gly2704Glu (GGA&gt;GAA), was identified in a Chinese family with DEB-Pr.	Glycine	15-22	collagen type VII alpha 1 chain	Homo sapiens	48-54
27965453-6	2016	The analysis of CCR5 point mutations showed that glycine-163 is critical for HIV-1 infectivity, while arginine-274 and aspartic acid-276 are critical for LukED cytotoxicity.	Glycine	49-56	C-C motif chemokine receptor 5	Homo sapiens	16-20
27909292-6	2016	The symmetrically related TM2 and TM5 helices are kinked at the conserved glycine clusters, and these kinks are important for the channel activity.	Glycine	74-81	tropomyosin 3	Homo sapiens	34-37
27874011-4	2016	Considering the clinical safety and efficacy of GlyT1 inhibitors in raising glycine levels in clinical trials for schizophrenia, we propose that GlyT1 inhibitors have the potential to be repurposed as a treatment of both obesity and diabetes.	Glycine	76-83	solute carrier family 6 member 9	Rattus norvegicus	48-53
27874011-4	2016	Considering the clinical safety and efficacy of GlyT1 inhibitors in raising glycine levels in clinical trials for schizophrenia, we propose that GlyT1 inhibitors have the potential to be repurposed as a treatment of both obesity and diabetes.	Glycine	76-83	solute carrier family 6 member 9	Rattus norvegicus	145-150
27736076-6	2016	We apply these methods to a family of short elastin-like peptides (ELPs), fragments of the elastin protein based around the Pro-Gly turn motif characteristic of the elastomeric segments of the full protein.	Glycine	128-131	elastin	Homo sapiens	44-51
27736076-6	2016	We apply these methods to a family of short elastin-like peptides (ELPs), fragments of the elastin protein based around the Pro-Gly turn motif characteristic of the elastomeric segments of the full protein.	Glycine	128-131	elastin	Homo sapiens	91-98
26497039-7	2016	Regarding the histopathological analysis, GLY increased S100beta staining in cerebral cortex and striatum, and GFAP in corpus callosum of 1-day-old rats 5 days after injection.	Glycine	42-45	S100 calcium binding protein B	Rattus norvegicus	56-64
26497039-8	2016	Finally, we verified that melatonin prevented the decrease of complex IV and CK activities and GSH concentrations, and the increase of MDA levels and S100beta staining caused by GLY.	Glycine	178-181	S100 calcium binding protein B	Rattus norvegicus	150-158
27666119-1	2016	Mitochondrial serine hydroxylmethyltransferase 2 (SHMT2) is a key enzyme in the serine/glycine synthesis pathway.	Glycine	87-94	serine hydroxymethyltransferase 2	Homo sapiens	14-48
27666119-1	2016	Mitochondrial serine hydroxylmethyltransferase 2 (SHMT2) is a key enzyme in the serine/glycine synthesis pathway.	Glycine	87-94	serine hydroxymethyltransferase 2	Homo sapiens	50-55
27581978-12	2016	Replacing D101 with glycine and R167 with lysine in NL4-3 Vif impaired its counteractivity to A3F and A3C.	Glycine	20-27	Vif	Human immunodeficiency virus 1	58-61
27581978-12	2016	Replacing D101 with glycine and R167 with lysine in NL4-3 Vif impaired its counteractivity to A3F and A3C.	Glycine	20-27	apolipoprotein B mRNA editing enzyme catalytic subunit 3C	Homo sapiens	102-105
27403535-1	2016	Glycine is a key rate-limiting component of heme biosynthesis in erythropoietic cells, where the high intracellular glycine demand is primarily supplied by the glycine transporter 1 (GlyT1).	Glycine	0-7	solute carrier family 6 member 9	Rattus norvegicus	160-181
27403535-1	2016	Glycine is a key rate-limiting component of heme biosynthesis in erythropoietic cells, where the high intracellular glycine demand is primarily supplied by the glycine transporter 1 (GlyT1).	Glycine	0-7	solute carrier family 6 member 9	Rattus norvegicus	183-188
27403535-1	2016	Glycine is a key rate-limiting component of heme biosynthesis in erythropoietic cells, where the high intracellular glycine demand is primarily supplied by the glycine transporter 1 (GlyT1).	Glycine	116-123	solute carrier family 6 member 9	Rattus norvegicus	160-181
27403535-1	2016	Glycine is a key rate-limiting component of heme biosynthesis in erythropoietic cells, where the high intracellular glycine demand is primarily supplied by the glycine transporter 1 (GlyT1).	Glycine	116-123	solute carrier family 6 member 9	Rattus norvegicus	183-188
27296115-0	2016	BDNF modulates glycine uptake in hippocampal synaptosomes by decreasing membrane insertion of glycine transporter 2.	Glycine	15-22	brain-derived neurotrophic factor	Rattus norvegicus	0-4
27296115-4	2016	We herein show that BDNF decreases [(3)H]glycine uptake mediated by GlyT2 in isolated nerve endings (synaptosomes) obtained from rat hippocampus, by reducing the maximum velocity (Vmax) of transport while not influencing the transporter affinity constant (Km) for glycine.	Glycine	41-48	brain-derived neurotrophic factor	Rattus norvegicus	20-24
27296115-6	2016	Monensin, a transporter recycling inhibitor, prevented the BDNF action upon glycine uptake, suggesting that BDNF reduces GlyT2 insertion in the plasma membrane.	Glycine	76-83	brain-derived neurotrophic factor	Rattus norvegicus	59-63
27296115-6	2016	Monensin, a transporter recycling inhibitor, prevented the BDNF action upon glycine uptake, suggesting that BDNF reduces GlyT2 insertion in the plasma membrane.	Glycine	76-83	brain-derived neurotrophic factor	Rattus norvegicus	108-112
27296115-7	2016	It is concluded that BDNF effect upon glycine uptake into glycinergic nerve terminals requires the activation of the TrkB-FL receptor and its canonical signalling pathways and occurs by inhibiting GlyT2 membrane incorporation.	Glycine	38-45	brain-derived neurotrophic factor	Rattus norvegicus	21-25
27684555-5	2016	Codon usage at these glycines is highly conserved in KRAS compared to HRAS, indicating selective pressure.	Glycine	21-29	KRAS proto-oncogene, GTPase	Homo sapiens	53-57
27682166-3	2016	Fibrillarin is a highly conserved protein; however, in the course of evolution from archaea to eukaryotes, it acquired an additional N-terminal glycine and arginine-rich (GAR) domain.	Glycine	144-151	fibrillarin	Homo sapiens	0-11
27238888-4	2016	ARHGEF9 encodes for collybistin which plays an important role in post synaptic clustering of glycine and inhibitory gamma-aminobutyric acid receptors along with its scaffolding partner, gephyrin.	Glycine	93-100	Cdc42 guanine nucleotide exchange factor 9	Homo sapiens	0-7
27610301-1	2016	BACKGROUND: hGlyrichin is a novel human antimicrobial peptide rich in glycine.	Glycine	70-77	reactive oxygen species modulator 1	Homo sapiens	12-22
10194377-1	1999	The sequence of granulocyte colony-stimulating factor (G-CSF) has been circularly permuted by introducing new chain termini into interhelical loops and by constraining the N- and C-terminal helices, either by direct linkage of the termini (L0) or by substitution of the amino-terminal 10-residue segment with a seven-residue linker composed of glycines and serines (L1).	Glycine	344-352	colony stimulating factor 3	Homo sapiens	55-60
10198322-4	1999	Secretin and secretin-Gly were noted to coelute during reverse-phase HPLC.	Glycine	22-25	SCT	Canis lupus familiaris	13-21
10198322-8	1999	Secretin-Gly and secretin-Gly-Lys-Arg had potencies of 81 +/- 9% (P &gt; 0.05) and 176 +/- 13% (P &lt; 0.01), respectively, compared with amidated secretin, and the response to secretin-Gly-Lys-Arg lasted significantly longer.	Glycine	9-12	SCT	Canis lupus familiaris	0-8
10198322-8	1999	Secretin-Gly and secretin-Gly-Lys-Arg had potencies of 81 +/- 9% (P &gt; 0.05) and 176 +/- 13% (P &lt; 0.01), respectively, compared with amidated secretin, and the response to secretin-Gly-Lys-Arg lasted significantly longer.	Glycine	9-12	SCT	Canis lupus familiaris	147-155
27391339-2	2016	Increased de novo biosynthesis of glycine by serine hydroxymethyltransferase 2 (SHMT2) is the central mechanism to fuel one-carbon pools supporting tumorigenesis.	Glycine	34-41	serine hydroxymethyltransferase 2	Homo sapiens	45-78
10198322-8	1999	Secretin-Gly and secretin-Gly-Lys-Arg had potencies of 81 +/- 9% (P &gt; 0.05) and 176 +/- 13% (P &lt; 0.01), respectively, compared with amidated secretin, and the response to secretin-Gly-Lys-Arg lasted significantly longer.	Glycine	9-12	SCT	Canis lupus familiaris	147-155
27391339-2	2016	Increased de novo biosynthesis of glycine by serine hydroxymethyltransferase 2 (SHMT2) is the central mechanism to fuel one-carbon pools supporting tumorigenesis.	Glycine	34-41	serine hydroxymethyltransferase 2	Homo sapiens	80-85
10198322-8	1999	Secretin-Gly and secretin-Gly-Lys-Arg had potencies of 81 +/- 9% (P &gt; 0.05) and 176 +/- 13% (P &lt; 0.01), respectively, compared with amidated secretin, and the response to secretin-Gly-Lys-Arg lasted significantly longer.	Glycine	26-29	SCT	Canis lupus familiaris	17-25
27391339-11	2016	Moreover, our results suggest that glycine, but not 5,10-methylenetetrahydrofolate, from the SHMT2-mediated enzymatic reaction is instrumental in tumorigenesis.	Glycine	35-42	serine hydroxymethyltransferase 2	Homo sapiens	93-98
27391339-12	2016	Indeed, we found that SHMT2-knockdown cells exhibited increased glycine uptake.	Glycine	64-71	serine hydroxymethyltransferase 2	Homo sapiens	22-27
10198322-8	1999	Secretin-Gly and secretin-Gly-Lys-Arg had potencies of 81 +/- 9% (P &gt; 0.05) and 176 +/- 13% (P &lt; 0.01), respectively, compared with amidated secretin, and the response to secretin-Gly-Lys-Arg lasted significantly longer.	Glycine	26-29	SCT	Canis lupus familiaris	147-155
10198322-8	1999	Secretin-Gly and secretin-Gly-Lys-Arg had potencies of 81 +/- 9% (P &gt; 0.05) and 176 +/- 13% (P &lt; 0.01), respectively, compared with amidated secretin, and the response to secretin-Gly-Lys-Arg lasted significantly longer.	Glycine	26-29	SCT	Canis lupus familiaris	147-155
10198322-9	1999	These data demonstrate that 1) amidated secretin and secretin-Gly are not separable under some chromatographic conditions, 2) current RIA may not detect bioactive COOH-terminally extended forms of secretin in tissue extracts or blood, and 3) the secretin receptor mediating stimulation of pancreatic secretion recognizes both amidated and COOH-terminally extended secretins.	Glycine	62-65	SCT	Canis lupus familiaris	53-61
10090759-4	1999	In the presence of glycine and succinyl-CoA, a quinonoid intermediate absorption is transiently observed in the visible spectrum of purified murine erythroid ALAS.	Glycine	19-26	aminolevulinic acid synthase 1	Mus musculus	158-162
27315223-0	2016	Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.	Glycine	97-104	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	15-21
27315223-5	2016	Loss of MTHFD2 caused MCF7 cells to become glycine auxotrophs, that is, reliant on exogenous glycine, and more sensitive to exogenous folate depletion.	Glycine	43-50	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	8-14
27315223-5	2016	Loss of MTHFD2 caused MCF7 cells to become glycine auxotrophs, that is, reliant on exogenous glycine, and more sensitive to exogenous folate depletion.	Glycine	93-100	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	8-14
27225947-7	2016	Glycine also resulted in decreased mRNA expression of muscle atrophy F-box (MAFbx) and muscle RING finger 1 (MuRF1) in gastrocnemius muscle.	Glycine	0-7	F-box protein 32	Homo sapiens	76-81
10192949-1	1999	The minimum energy paths for intramolecular proton transfer between the amino nitrogen and carbonyl oxygen atoms in gaseous protonated glycine were estimated at the Hartree-Fock (HF) and second-order Moller-Plesset Perturbation (MP2) levels of theory.	Glycine	135-142	tryptase pseudogene 1	Homo sapiens	229-232
27021905-4	2016	The disease is caused by a point mutation in the tubulin-specific chaperone E (Tbce) gene, leading to an exchange of the most C-terminal amino acid tryptophan to glycine.	Glycine	162-169	tubulin-specific chaperone E	Mus musculus	49-77
27021905-4	2016	The disease is caused by a point mutation in the tubulin-specific chaperone E (Tbce) gene, leading to an exchange of the most C-terminal amino acid tryptophan to glycine.	Glycine	162-169	tubulin-specific chaperone E	Mus musculus	79-83
26506510-0	2016	Nonsynaptic glycine release is involved in the early KCC2 expression.	Glycine	12-19	solute carrier family 12 member 5	Homo sapiens	53-57
26506510-7	2016	Blocking the vesicular release of neurotransmitters did not impinge on strychnine effect whereas blocking volume-sensitive outwardly rectifying (VSOR) chloride channels reproduced the GlyR blockade, suggesting that KCC2 is controlled by a glycine release from progenitor radial cells in immature ventral spinal networks.	Glycine	239-246	solute carrier family 12 member 5	Homo sapiens	215-219
27085409-11	2016	However, ruminal valerate (1.01 versus 1.17 mol/100 mol) and plasma Gly (172 versus 188 microM) were lowest with feeding p.m.-cut TIM.	Glycine	68-71	triosephosphate isomerase 1	Bos taurus	130-133
27350173-5	2016	Skeletal muscle mRNA expression of serine/one-carbon/glycine biosynthesis pathway genes (Phgdh, Psat1 and Psph) and the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase-M (Pck2/PEPCK-M), increased during treatment with BA, and to a lesser extent GH (p &lt; 0.001, treatment x time interaction).	Glycine	53-60	phosphoserine phosphatase	Sus scrofa	106-110
32263314-3	2016	To this end, we prepared and characterized the matrix metalloprotease-2 (MMP-2)/MMP-9-sensitive linker of the proline-valine-glycine-leucine-isoleucine-glycine (Pro-Val-Gly-Leu-Ile-Gly, PVGLIG) oligopeptide via a convenient and fast liquid-phase synthesis.	Glycine	125-132	matrix metallopeptidase 2	Mus musculus	47-71
32263314-3	2016	To this end, we prepared and characterized the matrix metalloprotease-2 (MMP-2)/MMP-9-sensitive linker of the proline-valine-glycine-leucine-isoleucine-glycine (Pro-Val-Gly-Leu-Ile-Gly, PVGLIG) oligopeptide via a convenient and fast liquid-phase synthesis.	Glycine	125-132	matrix metallopeptidase 2	Mus musculus	73-78
32263314-3	2016	To this end, we prepared and characterized the matrix metalloprotease-2 (MMP-2)/MMP-9-sensitive linker of the proline-valine-glycine-leucine-isoleucine-glycine (Pro-Val-Gly-Leu-Ile-Gly, PVGLIG) oligopeptide via a convenient and fast liquid-phase synthesis.	Glycine	152-159	matrix metallopeptidase 2	Mus musculus	47-71
32263314-3	2016	To this end, we prepared and characterized the matrix metalloprotease-2 (MMP-2)/MMP-9-sensitive linker of the proline-valine-glycine-leucine-isoleucine-glycine (Pro-Val-Gly-Leu-Ile-Gly, PVGLIG) oligopeptide via a convenient and fast liquid-phase synthesis.	Glycine	152-159	matrix metallopeptidase 2	Mus musculus	73-78
26957348-10	2016	Greater Delta LS BMD, but smaller Delta fracture numbers were observed on Pamidronate for helical glycine mutations in COL1A1 vs. COL1A2.	Glycine	98-105	collagen type I alpha 1 chain	Homo sapiens	119-125
26780567-3	2016	At the same time period of postnatal development, the transmembrane chloride gradient is changed due to increased expression of the potassium-chloride cotransporter (KCC2), thereby shifting the GABA- and glycine-mediated synaptic currents from mostly excitatory depolarization to inhibitory hyperpolarization.	Glycine	204-211	solute carrier family 12 member 5	Homo sapiens	166-170
26987812-11	2016	Importantly, we found that alanine substitution of helix-destabilizing glycines within the transmembrane segment and distinct residues within the luminal membrane-proximal segment led to a reduced efficiency of SPPL2a-mediated processing.	Glycine	71-79	signal peptide peptidase like 2A	Mus musculus	211-217
26833794-3	2016	D-amino acid oxidase (DAO) degrades neutral D-amino acids such as D-serine, the primary endogenous co-agonist acting at the glycine site of the synaptic NMDAR.	Glycine	124-131	D-amino acid oxidase	Mus musculus	0-20
26833794-3	2016	D-amino acid oxidase (DAO) degrades neutral D-amino acids such as D-serine, the primary endogenous co-agonist acting at the glycine site of the synaptic NMDAR.	Glycine	124-131	D-amino acid oxidase	Mus musculus	22-25
26956095-5	2016	These integrins are known to specifically interact with vitronectin and collagen-IV, respectively, through binding to an Arg-Gly-Asp (RGD) sequence.	Glycine	125-128	vitronectin	Homo sapiens	56-67
26843416-3	2016	The aim of this study is to investigate the effects of a selective GlyT-1 inhibitor that can increase endogenous glycine concentration on the micturition reflex in urethane-anesthetized rats.	Glycine	113-120	solute carrier family 6 member 9	Rattus norvegicus	67-73
26824641-5	2016	As serine and glycine can be reversibly metabolized by serine hydroxymethyltransferase 2 (SHMT2), we assessed the abundance of SHMT2 transcript as well as its functional role by inhibiting it with aminomethylphosphonic acid (AMPA), a glycine analog, during in vitro culture.	Glycine	14-21	serine hydroxymethyltransferase 2	Homo sapiens	55-88
26824641-5	2016	As serine and glycine can be reversibly metabolized by serine hydroxymethyltransferase 2 (SHMT2), we assessed the abundance of SHMT2 transcript as well as its functional role by inhibiting it with aminomethylphosphonic acid (AMPA), a glycine analog, during in vitro culture.	Glycine	14-21	serine hydroxymethyltransferase 2	Homo sapiens	90-95
26824641-5	2016	As serine and glycine can be reversibly metabolized by serine hydroxymethyltransferase 2 (SHMT2), we assessed the abundance of SHMT2 transcript as well as its functional role by inhibiting it with aminomethylphosphonic acid (AMPA), a glycine analog, during in vitro culture.	Glycine	14-21	serine hydroxymethyltransferase 2	Homo sapiens	127-132
26631721-7	2016	Because p35 is myristoylated at the N-terminal glycine, the possible ubiquitination sites are the lysine residues in p35.	Glycine	47-54	cyclin dependent kinase 5 regulatory subunit 1	Homo sapiens	8-11
26677223-7	2016	These studies reveal a novel rheological strategy in which the incorporation of a single glycine within the GPIbalpha binding interface of normal VWF enhances the probability of local unfolding that enables the A1 domain to conformationally adapt to shear flow while maintaining its overall native structure.	Glycine	89-96	glycoprotein Ib platelet subunit alpha	Homo sapiens	108-117
26857796-3	2016	Glycine and D-serine are endogenous ligands to the NMDA modulatory site, but since high doses are needed to affect brain levels, related compounds are being developed, for example glycine transport (GlyT) inhibitors to potentially elevate brain glycine or targeting enzymes, such as D-amino acid oxidase (DAAO) to slow the breakdown and increase the brain level of D-serine.	Glycine	0-7	D-amino acid oxidase	Mus musculus	283-303
26774480-4	2016	Examination of the serine-glycine synthesis pathway reveals that KDM4C epigenetically activates the pathway genes under steady-state and serine deprivation conditions by removing the repressive histone modification H3 lysine 9 (H3K9) trimethylation.	Glycine	26-33	lysine demethylase 4C	Homo sapiens	65-70
26519205-10	2016	We also identified an inactive COOH-terminal glycine deleted-EP that retains its binding-activity to EBP and that is able to inhibit the in vitro and in vivo activities of emphysema-inducing EP.	Glycine	45-52	phenylalkylamine Ca2+ antagonist (emopamil) binding protein	Mus musculus	101-104
27433358-3	2016	Selective knockout of the trkB gene resulted in a marked reduction in contacts made by VGLUT2- and GAD67-immunoreactive structures in both sexes and a significant reduction in contacts containing only glycine in male mice.	Glycine	201-208	neurotrophic tyrosine kinase, receptor, type 2	Mus musculus	26-30
25940868-8	2015	Glycine mutants located in TMD2 and TMD4 of M6a affected its dimerization, thus preventing M6a-induced filopodia formation in neurons.	Glycine	0-7	glycoprotein M6A	Homo sapiens	44-47
25940868-8	2015	Glycine mutants located in TMD2 and TMD4 of M6a affected its dimerization, thus preventing M6a-induced filopodia formation in neurons.	Glycine	0-7	glycoprotein M6A	Homo sapiens	91-94
26101830-2	2015	The glycine concentration in the synaptic cleft is controlled by the glycine transporters GlyT1 and GlyT2.	Glycine	4-11	solute carrier family 6 member 9	Rattus norvegicus	90-95
26101830-11	2015	The co-expression of GlyT1 and NMDA receptors in DRG suggests that GlyT1 regulates glycine concentration at the glycine binding site of the NMDA receptor.	Glycine	83-90	solute carrier family 6 member 9	Rattus norvegicus	21-26
25986737-4	2015	Here, we report that the m4 mAChR mimetic peptide m4i3c(14)Gly, comprising 14 residues in the junction between the intracellular third loop (i3c) and transmembrane helix VI (TM-VI) extended with a C-terminal glycine residue, presents GEF activity toward the Gi1 alpha subunit (Galphai1).	Glycine	59-62	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	234-237
26042340-3	2015	Substitution of Gly with l-Pro switched the receptor preference of the peptides from CXCR4 to CXCR7.	Glycine	16-19	C-X-C motif chemokine receptor 4	Homo sapiens	85-90
26042340-3	2015	Substitution of Gly with l-Pro switched the receptor preference of the peptides from CXCR4 to CXCR7.	Glycine	16-19	atypical chemokine receptor 3	Homo sapiens	94-99
25988540-10	2015	Glycine increased the mRNA expression of eNOS and decreased the expression of COX-2 and TNF-alpha.	Glycine	0-7	nitric oxide synthase 3	Rattus norvegicus	41-45
25988540-11	2015	Glycine improved the endothelium function in aged rats possibly by enhancing eNOS expression and reducing the role of superoxide anion and contractile prostanoids that increase the nitric oxide bioavailability.	Glycine	0-7	nitric oxide synthase 3	Rattus norvegicus	77-81
25344655-10	2015	The transcript levels of AOX, NHX1, and SOS1 were further upregulated; the upregulation of AOX was most pronounced with the highest NaCl concentration in the presence of glycine and only with 75 and 150 mM NaCl for NHX1 and SOS1.	Glycine	170-177	ubiquinol oxidase 1a, mitochondrial	Triticum aestivum	25-28
25344655-10	2015	The transcript levels of AOX, NHX1, and SOS1 were further upregulated; the upregulation of AOX was most pronounced with the highest NaCl concentration in the presence of glycine and only with 75 and 150 mM NaCl for NHX1 and SOS1.	Glycine	170-177	ubiquinol oxidase 1a, mitochondrial	Triticum aestivum	91-94
25817250-5	2015	In conditions involving down regulated GSH homeostasis, GGC serves asa crucialrate-limiting substrate for GSH synthetase, the main enzyme responsible for condensing glycine with GGC to form the final thiol tripeptide, GSH.	Glycine	165-172	gamma-glutamylcyclotransferase	Homo sapiens	56-59
25545713-1	2015	Inhibitory neurotransmitters, gamma-aminobutyric acid (GABA) and glycine, are transported into synaptic vesicles by the vesicular GABA transporter (VGAT).	Glycine	65-72	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	120-146
10404512-0	1999	Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells.	Glycine	0-7	gastrin	Homo sapiens	17-24
25545713-1	2015	Inhibitory neurotransmitters, gamma-aminobutyric acid (GABA) and glycine, are transported into synaptic vesicles by the vesicular GABA transporter (VGAT).	Glycine	65-72	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	148-152
10404512-6	1999	In contrast, saturable binding of radiolabeled glycine-extended gastrin was seen on LoVo and HT 29 cells that was not inhibited by amidated gastrin (10(-6) M) nor by a gastrin/CCKB receptor antagonist (PD 134308).	Glycine	47-54	gastrin	Homo sapiens	64-71
10404512-7	1999	Glycine-extended gastrin induced a dose-dependent increase in [3H]thymidine uptake in LoVo (143 +/- 8% versus control at 10(-10) M) and HT 29 (151 +/- 11% versus control at 10(-10) M) cells that was not inhibited by PD 134308 or by a mitogen-activated protein (MAP) or ERK kinase (MEK) inhibitor (PD 98509).	Glycine	0-7	gastrin	Homo sapiens	17-24
25722375-4	2015	We herein present the 2.55 A crystal structure of HisRS complexed with tRNA(His), which reveals that G-1 recognition is principally nonspecific interactions on this base and is made possible by an enlarged binding pocket consisting of conserved glycines.	Glycine	245-253	histidyl-tRNA synthetase 1	Homo sapiens	50-55
26071206-13	2015	In a South Indian population, the ADRB2 Arg/Gly may not form a susceptible variant to develop asthma nor can be a standard predictive marker to bronchodilator response; nevertheless, the patterns in asthma severity can be predicted by analyzing this variant.	Glycine	44-47	adrenoceptor beta 2	Homo sapiens	34-39
10404512-8	1999	Glycine-extended gastrin did stimulate jun-kinase activity in LoVo and HT 29 cells.	Glycine	0-7	gastrin	Homo sapiens	17-24
10404512-10	1999	CONCLUSIONS: Glycine-extended gastrin receptors are present on human colon cancer cells that mediate glycine-extended gastrin"s trophic effects via a MEK-independent mechanism.	Glycine	13-20	gastrin	Homo sapiens	30-37
10404512-10	1999	CONCLUSIONS: Glycine-extended gastrin receptors are present on human colon cancer cells that mediate glycine-extended gastrin"s trophic effects via a MEK-independent mechanism.	Glycine	13-20	gastrin	Homo sapiens	118-125
10404512-10	1999	CONCLUSIONS: Glycine-extended gastrin receptors are present on human colon cancer cells that mediate glycine-extended gastrin"s trophic effects via a MEK-independent mechanism.	Glycine	101-108	gastrin	Homo sapiens	30-37
10404512-10	1999	CONCLUSIONS: Glycine-extended gastrin receptors are present on human colon cancer cells that mediate glycine-extended gastrin"s trophic effects via a MEK-independent mechanism.	Glycine	101-108	gastrin	Homo sapiens	118-125
26302999-0	2015	Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs Modulates CXCR1/2 Expression and Activation in Cartilage Endplate Stem Cells to Induce Migration and Differentiation Toward a Pro-Inflammatory Phenotype.	Glycine	38-45	C-X-C motif chemokine receptor 1	Homo sapiens	88-93
25363567-1	2015	A "double-hydrophobic" elastin-like triblock polypeptide GPG has been constructed by mimicking the localization of proline- and glycine-rich hydrophobic domains of native elastin, a protein that provides elasticity and resilience to connective tissues.	Glycine	128-135	elastin	Homo sapiens	23-30
25363567-1	2015	A "double-hydrophobic" elastin-like triblock polypeptide GPG has been constructed by mimicking the localization of proline- and glycine-rich hydrophobic domains of native elastin, a protein that provides elasticity and resilience to connective tissues.	Glycine	128-135	elastin	Homo sapiens	171-178
10404512-11	1999	This suggests that glycine-extended gastrin and its novel receptors may play a role in colon cancer cell growth.	Glycine	19-26	gastrin	Homo sapiens	36-43
10026140-2	1999	CyPA binds to the previously identified Gly-Pro90 site of the capsid protein p24, but its role remained unclear.	Glycine	40-43	peptidylprolyl isomerase A	Homo sapiens	0-4
10026140-5	1999	Peptides corresponding to these regions showed higher affinities (Kd approximately 0.3 microM) for both CyPA and cyclophilin B than the best peptide derived from the Gly-Pro90 site ( approximately 8 microM) and thus revealed new sequence motifs flanking Gly-Pro that are important for tight interaction of peptide ligands with cyclophilins.	Glycine	166-169	peptidylprolyl isomerase A	Homo sapiens	104-108
10026140-5	1999	Peptides corresponding to these regions showed higher affinities (Kd approximately 0.3 microM) for both CyPA and cyclophilin B than the best peptide derived from the Gly-Pro90 site ( approximately 8 microM) and thus revealed new sequence motifs flanking Gly-Pro that are important for tight interaction of peptide ligands with cyclophilins.	Glycine	166-169	peptidylprolyl isomerase A	Homo sapiens	327-339
25630222-8	2015	Among them, compounds 4 and 14 interact with NQO1 at Gly 149, Gly 150, Phe 106, Typ 105 and His 161, revealed by molecular docking studies.	Glycine	53-56	NAD(P)H dehydrogenase, quinone 1	Mus musculus	45-49
10026140-6	1999	Between CyPA and an immature (unprocessed) form of p24, a Kd of approximately 8 microM was measured, which corresponded with the Kd of the best of the Gly-Pro90 peptides, indicating an association via this site.	Glycine	151-154	peptidylprolyl isomerase A	Homo sapiens	8-12
9988709-3	1999	A cDNA encoding TrxR2 was cloned from rat liver; the open reading frame predicts a polypeptide of 526 amino acids with a COOH-terminal Gly-Cys-Secys-Gly motif provided that an in-frame TGA codon encodes Secys.	Glycine	135-138	thioredoxin reductase 2	Rattus norvegicus	16-21
25300471-8	2015	The present results show that the stimulation of the NMDA receptor through the glycine site on the receptor either directly with D-serine or by blocking glycine transporter-1 attenuates the immobility elicited by the subchronic administration of MK-801 and may be potentially useful for the treatment of negative symptoms of schizophrenia.	Glycine	79-86	solute carrier family 6 member 9	Rattus norvegicus	153-174
9988709-3	1999	A cDNA encoding TrxR2 was cloned from rat liver; the open reading frame predicts a polypeptide of 526 amino acids with a COOH-terminal Gly-Cys-Secys-Gly motif provided that an in-frame TGA codon encodes Secys.	Glycine	149-152	thioredoxin reductase 2	Rattus norvegicus	16-21
24903887-7	2015	For CK2alpha, the affected positions are distributed over the glycine-rich loop (G-loop), C-loop, and the beta4/beta5 loop.	Glycine	62-69	casein kinase 2 alpha 2	Homo sapiens	4-12
10226806-2	1999	Human and rat IGFBP-6 lack 2 and 4 N-terminal cysteines and therefore the Gly-Cys-Gly-Cys-Cys motif present in IGFBPs 1-5.	Glycine	74-77	insulin-like growth factor binding protein 1	Rattus norvegicus	111-121
25451937-0	2015	Internal dynamics of dynactin CAP-Gly is regulated by microtubules and plus end tracking protein EB1.	Glycine	34-37	microtubule associated protein RP/EB family member 1	Homo sapiens	97-100
25451937-3	2015	To understand its origin, we addressed internal dynamics of CAP-Gly assembled on polymeric microtubules, bound to end-binding protein EB1 and free, by magic angle spinning NMR and molecular dynamics simulations.	Glycine	64-67	microtubule associated protein RP/EB family member 1	Homo sapiens	134-137
25451937-5	2015	On the contrary, CAP-Gly bound to EB1 is significantly more rigid.	Glycine	21-24	microtubule associated protein RP/EB family member 1	Homo sapiens	34-37
26226959-9	2015	Additionally, there were positive correlations between glycine and IL-1beta as well as glycine and IL-2, while negative correlation existed between C18:2 and TNF-alpha.	Glycine	55-62	interleukin-1 beta	Ovis aries	67-75
10226806-2	1999	Human and rat IGFBP-6 lack 2 and 4 N-terminal cysteines and therefore the Gly-Cys-Gly-Cys-Cys motif present in IGFBPs 1-5.	Glycine	82-85	insulin-like growth factor binding protein 1	Rattus norvegicus	111-121
10024091-4	1999	Recently, it was reported that GLP-1 became resistant to DPPIV when the alanine residue at position 8 was replaced by a glycine (GLP-1-Gly8).	Glycine	120-127	dipeptidyl peptidase 4	Homo sapiens	57-62
9932724-4	1999	This study examines the effects on histamine release from the vascularly perfused rat stomach of amidated gastrin-17, COOH-terminal glycine-extended gastrin-17, gastrin-17 extended at the COOH-terminal including the remaining progastrin sequence, and carboxy-terminal progastrin fragments (SAEDEN and GRRSAEDEN).	Glycine	132-139	gastrin	Homo sapiens	149-156
25354296-6	2015	Substitution mutations at all nine serine and threonine residues in the ALK2 glycine- and serine-rich domain simultaneously inhibited this enhancement by the type II receptors.	Glycine	77-84	activin A receptor type 1	Homo sapiens	72-76
9852045-8	1998	Substitution of these amino acids demonstrated that a glycine residue at position 433 in STAT5B and a glutamic residue at a similar position in STAT5A determined the DNA binding specificity.	Glycine	54-61	signal transducer and activator of transcription 5A	Homo sapiens	144-150
25253739-4	2014	Interestingly, bioactive mouse GDF9 and human BMP15 share the conserved arginine in the pre-helix loop, but their low-activity counterparts (mouse BMP15 and human GDF9) have a glycine or a proline instead.	Glycine	176-183	growth differentiation factor 9	Homo sapiens	163-167
9806894-11	1998	The large Dk indicated that the glycine hydroxylation catalysed by PHM might proceed in a stepwise mechanism similar to that proposed for the dopamine beta-hydroxylase reaction [Miller and Klinman (1983) Biochemistry 22, 3091-3096].	Glycine	32-39	dopamine beta-hydroxylase	Homo sapiens	142-167
24650211-3	2014	Of the three peptides, Gly-Pro-Hyp was a true peptidic inhibitor of dipeptidylpeptidase-IV (DPP-IV), because DPP-IV could not hydrolyze the bond between Pro-Hyp.	Glycine	23-26	dipeptidyl peptidase 4	Bos taurus	68-90
24650211-3	2014	Of the three peptides, Gly-Pro-Hyp was a true peptidic inhibitor of dipeptidylpeptidase-IV (DPP-IV), because DPP-IV could not hydrolyze the bond between Pro-Hyp.	Glycine	23-26	dipeptidyl peptidase 4	Bos taurus	92-98
24650211-3	2014	Of the three peptides, Gly-Pro-Hyp was a true peptidic inhibitor of dipeptidylpeptidase-IV (DPP-IV), because DPP-IV could not hydrolyze the bond between Pro-Hyp.	Glycine	23-26	dipeptidyl peptidase 4	Bos taurus	109-115
9806950-1	1998	In the course of glycine conjugation, benzoic acid is successively converted into benzoyl-CoA and benzoylglycine by mitochondrial enzymes (i.e. benzoyl-CoA synthetase and benzoyl-CoA/glycine N-acyltransferase, respectively), utilizing ATP, CoA, and glycine.	Glycine	17-24	glycine-N-acyltransferase	Rattus norvegicus	183-208
25259833-8	2014	Wild-type glycine (G) at position 190 is encoded by GGC in more than 99% of published A(FSU) strains.	Glycine	10-17	gamma-glutamylcyclotransferase	Homo sapiens	52-55
9806950-1	1998	In the course of glycine conjugation, benzoic acid is successively converted into benzoyl-CoA and benzoylglycine by mitochondrial enzymes (i.e. benzoyl-CoA synthetase and benzoyl-CoA/glycine N-acyltransferase, respectively), utilizing ATP, CoA, and glycine.	Glycine	105-112	glycine-N-acyltransferase	Rattus norvegicus	183-208
9804190-6	1998	We report here site-directed mutagenesis experiments which have led to the identification of two other amino acid residues, glycine 38 and 111, whose substitution in the polypeptide chain of the first generation dimeric mutant of RNase A, is capable of conferring to the mutein the full cytotoxic activity characteristic of native seminal RNase.	Glycine	124-131	seminal ribonuclease	Bos taurus	331-344
25231980-0	2014	Glycine induces bidirectional modifications in N-methyl-D-aspartate receptor-mediated synaptic responses in hippocampal CA1 neurons.	Glycine	0-7	carbonic anhydrase 1	Homo sapiens	120-123
25231980-3	2014	Here, we report that glycine induces long-term potentiation (LTP) or long-term depression (LTD) of NMDA responses (Gly-LTP(NMDA) or Gly-LTD(NMDA)) in a dose-dependent manner in hippocampal CA1 neurons.	Glycine	21-28	carbonic anhydrase 1	Homo sapiens	189-192
25168305-5	2014	In tissue-culture-expressed GlyT1 at least two of these mutations altered the sensitivity of GlyT1 surface expression and glycine uptake to calmodulin antagonists.	Glycine	122-129	calmodulin 2	Mus musculus	140-150
9765602-5	1998	Several Lys-Ser-Gly repeats are present in the basic region of the hnRNP C proteins.	Glycine	16-19	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	67-74
25207865-2	2014	Herein, we report the construction of arginine-glycine-aspartic acid-cysteine (RGDC) tetrapeptide functionalized and 10-hydroxycamptothecin (HCPT)-encapsulated magnetic nanohybrids (RFHEMNs) for integrin alphaVbeta3-targeted drug delivery.	Glycine	47-54	integrin subunit alpha V	Homo sapiens	195-215
9873480-1	1998	Novel Leu-enkephalin (Leu-Enk) (1) analogs possessing various types of alpha-substituted serine instead of its glycine residue in the position 2 were synthesized via an efficient O,N-migration method.	Glycine	111-118	proenkephalin	Rattus norvegicus	26-29
25274726-5	2014	Interestingly, several of the tumor-promoting functions of CtsZ were not dependent on its described catalytic activity but instead were mediated via the Arg-Gly-Asp (RGD) motif in the enzyme prodomain, which regulated interactions with integrins and the extracellular matrix.	Glycine	157-160	cathepsin Z	Homo sapiens	59-63
24996626-4	2014	ATG4 processes ATG8 precursor to expose its C-terminal glycine for phosphatidyl ethanolamine (PE) lipidation.	Glycine	55-62	cysteine protease ATG4B	Triticum aestivum	0-4
9696767-8	1998	The single guanine-to-adenine transition in upc2-1 gives a predicted amino acid change from glycine to aspartic acid.	Glycine	92-99	Upc2p	Saccharomyces cerevisiae S288C	44-48
25039836-3	2014	Functional complementation of yeast GLY II mutant ( GLO2) and enzyme kinetics data suggested that OsGLYII-2 possesses characteristic GLY II activity using S-lactoylglutathione (SLG) as the substrate.	Glycine	100-103	hydroxyacylglutathione hydrolase GLO2	Saccharomyces cerevisiae S288C	52-56
25009140-8	2014	Pro 5 and Gly 6 adopt a type II tight turn and Lys 2"s zeta-NH3(+) is positioned to form a favorable cation-pi interaction with Trp 4"s indole ring.	Glycine	10-13	transient receptor potential cation channel subfamily C member 4	Homo sapiens	128-133
9749667-3	1998	Analysis of three genes required for synthesis of glutamine, glycine and 10-formyl tetrahydrofolate (GLN1, SHM2 and MTD1, respectively) shows that their expression is repressed by adenine and requires the transcription factors Baslp and Bas2p.	Glycine	61-68	methylenetetrahydrofolate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	116-120
24147951-1	2014	CONTEXT: Selective inhibitors of glycine transporter type 1 (GlyT1) increase synaptic glycine concentrations and are being developed to treat cognitive and negative symptoms of schizophrenia.	Glycine	33-40	solute carrier family 6 member 9	Rattus norvegicus	61-66
9749667-3	1998	Analysis of three genes required for synthesis of glutamine, glycine and 10-formyl tetrahydrofolate (GLN1, SHM2 and MTD1, respectively) shows that their expression is repressed by adenine and requires the transcription factors Baslp and Bas2p.	Glycine	61-68	Pho2p	Saccharomyces cerevisiae S288C	237-242
24598217-2	2014	The synaptic glycine concentration is controlled by the two glycine transporters (GlyT) 1 and 2.	Glycine	13-20	solute carrier family 6 member 9	Rattus norvegicus	60-95
9632798-2	1998	hTRN1 interacts with the M9 region of hnRNP A1, a 38-amino-acid domain rich in Gly, Ser, and Asn, and mediates the nuclear import of M9-bearing proteins in vitro.	Glycine	79-82	tRNA-Asn (anticodon GTT) 2-7	Homo sapiens	0-5
9687065-7	1998	Another gene, ATA20, encodes a protein with novel repeat sequences and a glycine-rich domain that shares a predicted structure with a known cell wall protein.	Glycine	73-80	anther 20	Arabidopsis thaliana	14-19
24835171-3	2014	The down-regulation of co-transporter KCC2 after spinal cord transection in animals leads to the depolarising (excitatory) action of GABA and glycine and thus results in a reduction of inhibitory synaptic efficiency.	Glycine	142-149	solute carrier family 12 member 5	Homo sapiens	38-42
9762332-1	1998	BACKGROUND AND METHODS: Recent studies suggest that glycine-extended gastrin (G17-gly) stimulates in vitro proliferation of the pancreatic cell line AR4-2J, through selective receptors distinct from the CCK-B/G-receptor mediating the effects of amidated gastrin (G17).	Glycine	52-59	gastrin	Homo sapiens	69-76
9762332-1	1998	BACKGROUND AND METHODS: Recent studies suggest that glycine-extended gastrin (G17-gly) stimulates in vitro proliferation of the pancreatic cell line AR4-2J, through selective receptors distinct from the CCK-B/G-receptor mediating the effects of amidated gastrin (G17).	Glycine	52-59	gastrin	Homo sapiens	254-261
9584216-5	1998	Glycine, alanine, valine, leucine, phenylalanine, and asparagine produced constitutive activation in a COS-7 cell expression system (3-5-fold increase in basal cAMP), but glutamate did not, indicating that a negative charge at position 564 may be important for maintaining the inactive LHR conformation.	Glycine	0-7	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	286-289
9525931-10	1998	These results suggest that a specific amino acid, Gly-819, is critical for the action of volatile anesthetics, but not of ethanol or pentobarbital, on the GluR6 receptor.	Glycine	50-53	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	155-160
9546718-2	1998	Bovine UCRP retains the Leu-Arg-Gly-Gly C-terminal sequence of ubiquitin that ligates to and directs degradation of cytosolic proteins.	Glycine	32-35	ISG15 ubiquitin like modifier	Bos taurus	7-11
9546718-2	1998	Bovine UCRP retains the Leu-Arg-Gly-Gly C-terminal sequence of ubiquitin that ligates to and directs degradation of cytosolic proteins.	Glycine	36-39	ISG15 ubiquitin like modifier	Bos taurus	7-11
9546654-6	1998	Pharmacological characterization of crude membrane preparations of the recombinant yeast cells showed saturable binding of the glycine antagonist [3H]MDL105,519 with Kd values of 56.9 +/- 6.19 nM (NR1a/NR2A), 26.72 +/- 2.13 nM (NR1a/NR2B), and 21.22 +/- 1.64 nM (NR1a/NR2C), and bound capacities of 17.94 +/- 1.24 pmol/mg membrane protein (NR1a/NR2A), 11.45 +/- 0.67 pmol/mg (NR1a/NR2B), and 16.15 +/- 0.86 (NR1a/NR2C) pmol/mg.	Glycine	127-134	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	233-237
9546654-6	1998	Pharmacological characterization of crude membrane preparations of the recombinant yeast cells showed saturable binding of the glycine antagonist [3H]MDL105,519 with Kd values of 56.9 +/- 6.19 nM (NR1a/NR2A), 26.72 +/- 2.13 nM (NR1a/NR2B), and 21.22 +/- 1.64 nM (NR1a/NR2C), and bound capacities of 17.94 +/- 1.24 pmol/mg membrane protein (NR1a/NR2A), 11.45 +/- 0.67 pmol/mg (NR1a/NR2B), and 16.15 +/- 0.86 (NR1a/NR2C) pmol/mg.	Glycine	127-134	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	381-385
9485449-4	1998	In this paper we examine the effect of a model osmolyte, glycine, on the stabilization of two proteins, chymotrypsin inhibitor 2 and horse heart cytochrome c.	Glycine	57-64	cytochrome c, somatic	Equus caballus	145-157
9489750-2	1998	We found that glutamate, NMDA, glycine, and D-serine were significantly more potent on hNMDAR1A/2D than on hNMDAR1A/2A or hNMDAR1A/2B.	Glycine	31-38	glutamate ionotropic receptor NMDA type subunit 2D	Homo sapiens	87-98
9489750-3	1998	Also, the potencies of NMDA and glycine were higher for hNMDAR1A/2D than for hNMDAR1A/2C.	Glycine	32-39	glutamate ionotropic receptor NMDA type subunit 2D	Homo sapiens	56-67
9489750-6	1998	Kinetic measurements revealed that the higher affinity of hNMDAR1A/2D for both glutamate and glycine relative to hNMDAR1A/2A and hNMDA1A/2B can be explained by slower dissociation of each agonist from hNMDAR1A/2D.	Glycine	93-100	glutamate ionotropic receptor NMDA type subunit 2D	Homo sapiens	58-69
9489750-6	1998	Kinetic measurements revealed that the higher affinity of hNMDAR1A/2D for both glutamate and glycine relative to hNMDAR1A/2A and hNMDA1A/2B can be explained by slower dissociation of each agonist from hNMDAR1A/2D.	Glycine	93-100	glutamate ionotropic receptor NMDA type subunit 2D	Homo sapiens	201-212
9490812-5	1998	Equilibrium concentration-response curves showed that recombinant human alpha1(K276E)beta receptors had a 29-fold lower glycine sensitivity than wild-type alpha1beta receptors, and a greatly reduced Hill coefficient.	Glycine	120-127	adrenoceptor alpha 1D	Homo sapiens	72-77
9490812-12	1998	The main effect of the alpha1(K276E) mutation is to impair the opening of the channel rather than the binding of glycine.	Glycine	113-120	adrenoceptor alpha 1D	Homo sapiens	23-28
9490030-8	1998	Glycine at position 53, also in the first transmembrane domain in the human beta3-AR, has been suggested to participate in beta2-/beta3-AR subtype selectivity.	Glycine	0-7	adrenoceptor beta 3	Homo sapiens	76-84
9490030-8	1998	Glycine at position 53, also in the first transmembrane domain in the human beta3-AR, has been suggested to participate in beta2-/beta3-AR subtype selectivity.	Glycine	0-7	adrenoceptor beta 3	Homo sapiens	130-138
9490030-9	1998	Replacement of this glycine residue by phenylalanine, which is the residue present at the homologous position in the human beta2-AR, left the beta3-AR pharmacological profile unaltered in terms of specificity and selectivity.	Glycine	20-27	adrenoceptor beta 3	Homo sapiens	142-150
9490031-7	1998	Two enzymes have been found to be induced by glycine: ornithine decarboxylase and aspartate transcarbamoylase (aspartate carbamoyltransferase).	Glycine	45-52	ornithine decarboxylase 1	Rattus norvegicus	54-77
9469933-4	1998	Other highly conserved chicken and human CLIP-170/Restin regions confirm the importance of certain protein domains as crucial for protein function, including two CAP-Gly microtubule-binding motifs in the N-terminal globular head domain and two CCHC metal-binding motifs in the C-terminal globular tail domain.	Glycine	166-169	collagen type XV alpha 1 chain	Homo sapiens	50-56
9925947-8	1998	The coding region of the gene differed from the GSTZ1 cDNA at two nucleotide positions in exon 3, resulting in Lys-32--&gt;Glu and Arg-42--&gt; Gly substitutions.	Glycine	144-147	glutathione S-transferase zeta 1	Homo sapiens	48-53
9491816-2	1998	The D3 receptor gene (DRD3) contains a polymorphism resulting in a serine-glycine substitution in the N-terminus of the receptor.	Glycine	74-81	dopamine receptor D3	Homo sapiens	22-26
9398309-0	1997	Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant.	Glycine	50-57	Dihydrofolate reductase	Escherichia coli	82-105
26474315-10	2015	All affected Basset Fauve de Bretagne dogs were homozygous for a missense mutation in exon 11 causing a glycine to serine amino acid substitution (G519S) in the disintegrin-like domain of ADAMTS17 which is predicted to alter protein function.	Glycine	104-111	ADAM metallopeptidase with thrombospondin type 1 motif 17	Canis lupus familiaris	188-196
9398309-1	1997	Two-dimensional heteronuclear (1H-15N) nuclear magnetic relaxation studies of dihydrofolate reductase (DHFR) from Escherichia coli have demonstrated that glycine-121 which is 19 A from the catalytic center of the enzyme has large-amplitude backbone motions on the nanosecond time scale [Epstein, D. M., Benkovic, S. J., and Wright, P. E. (1995) Biochemistry 34, 11037-11048].	Glycine	154-161	Dihydrofolate reductase	Escherichia coli	78-101
9398309-1	1997	Two-dimensional heteronuclear (1H-15N) nuclear magnetic relaxation studies of dihydrofolate reductase (DHFR) from Escherichia coli have demonstrated that glycine-121 which is 19 A from the catalytic center of the enzyme has large-amplitude backbone motions on the nanosecond time scale [Epstein, D. M., Benkovic, S. J., and Wright, P. E. (1995) Biochemistry 34, 11037-11048].	Glycine	154-161	Dihydrofolate reductase	Escherichia coli	103-107
9427531-3	1997	In contrast to LTBP-1 and LTBP-3, mouse LTBP-2 apparently is a more modular protein, with proline/glycine-rich sequences always alternating with clusters of cysteine-rich structural motifs.	Glycine	98-105	latent transforming growth factor beta binding protein 2	Mus musculus	40-46
26149650-10	2015	The results of this study indicated that the GLYAT ORF is highly conserved and supported the hypothesis that the glycine conjugation pathway is an essential detoxification pathway.	Glycine	113-120	glycine-N-acyltransferase	Homo sapiens	45-50
9385367-1	1997	The human androgen receptor gene (hAR) has a long, polymorphic trinucleotide (GGN; glycine)n repeat in the 3" portion of its first exon, with n = 10-31.	Glycine	83-90	lymphatic vessel endothelial hyaluronan receptor 1	Homo sapiens	34-37
27183783-5	2015	In gene promoter MIC-1/GDF15 was detected geroprotective binding sites for peptides Lys-Glu, Lys-Glu-Asp, and Ala-Glu-Asp-Gly.	Glycine	122-125	growth differentiation factor 15	Homo sapiens	17-22
27183783-5	2015	In gene promoter MIC-1/GDF15 was detected geroprotective binding sites for peptides Lys-Glu, Lys-Glu-Asp, and Ala-Glu-Asp-Gly.	Glycine	122-125	growth differentiation factor 15	Homo sapiens	23-28
9385632-5	1997	Comparison with the recently determined structures of CypA in complexes with larger fragments of the HIV-1 capsid protein demonstrates that CypA recognition of these hexapeptides involves contacts with peptide residues Ala(Val) 88, Gly 89, and Pro 90, and is independent of the context of longer sequences.	Glycine	232-235	peptidylprolyl isomerase A	Homo sapiens	140-144
25991579-3	2015	We uncovered preferential utilization of GGC for Gly, GCG for Ala, CCG for Pro, and TCG for Ser, in coding sequences (CDSs) that included MLL1 morphemes.	Glycine	49-52	gamma-glutamylcyclotransferase	Homo sapiens	41-44
9351806-10	1997	The presence of a type-I" turn in the BG loop, which is dependent on the presence of a glycine residue at position BG3, is indicative of a binding pocket, characteristic of the Src family, SykC and Abl, rather than a binding groove found in PLC-gamma 1C, p85 alpha N and Shc, for example.	Glycine	87-94	FYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	177-180
26304723-3	2015	Using in vitro models of neuronal plasticity, such as glycine-induced chemical long-term potentiation (LTP), known to evoke synaptic plasticity, or long-term depolarization block by KCl, leading to homeostatic morphological changes, we show that actin stabilization needed for the enlargement of dendritic spines is dependent on PKD activity.	Glycine	54-61	protein kinase D1	Homo sapiens	329-332
9335260-6	1997	Glycine (3-10 microM) or gp120 (0.003-0.01 microM) produced reversal of the 5,7-DCKA antagonism in a way that suggested competition at a same site; gp120 was at least 3 orders of magnitude more potent than glycine.	Glycine	0-7	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	148-153
9335260-6	1997	Glycine (3-10 microM) or gp120 (0.003-0.01 microM) produced reversal of the 5,7-DCKA antagonism in a way that suggested competition at a same site; gp120 was at least 3 orders of magnitude more potent than glycine.	Glycine	206-213	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	25-30
9335260-6	1997	Glycine (3-10 microM) or gp120 (0.003-0.01 microM) produced reversal of the 5,7-DCKA antagonism in a way that suggested competition at a same site; gp120 was at least 3 orders of magnitude more potent than glycine.	Glycine	206-213	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	148-153
9335260-7	1997	It is suggested that gp120 may mimic glycine at NMDA receptors.	Glycine	37-44	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	21-26
25960349-2	2015	The first glycine (G) residue in the pore helix of Kv7.2 (KCNQ2) subunit is highly conserved among different classes of Kv7 channel family.	Glycine	10-17	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	51-56
9324018-5	1997	RESULTS: Four (6%) of 72 patients with RA, 2 (13%) of 16 with OA, and 1 (8%) of 12 with other arthropathies harbored mutant H-ras proto-oncogenes, and were heterozygous at codon 13 for the GGT--&gt;GAT (Gly--&gt;Asp) change.	Glycine	203-206	HRas proto-oncogene, GTPase	Homo sapiens	124-129
25960349-2	2015	The first glycine (G) residue in the pore helix of Kv7.2 (KCNQ2) subunit is highly conserved among different classes of Kv7 channel family.	Glycine	10-17	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	58-63
9287969-2	1997	Glycine-extended gastrin (Gly-G) stimulates growth of a rat pancreatic acinar cell line; however, the effect of Gly-G on human gastric cancers is not known.	Glycine	0-7	gastrin	Homo sapiens	17-24
25795213-2	2015	DMG is degraded to glycine through a DMG-dehydrogenase (DMGDH)-catalyzed reaction, and this is the only known pathway for the breakdown of DMG in mammals.	Glycine	19-26	dimethylglycine dehydrogenase	Homo sapiens	37-54
25795213-2	2015	DMG is degraded to glycine through a DMG-dehydrogenase (DMGDH)-catalyzed reaction, and this is the only known pathway for the breakdown of DMG in mammals.	Glycine	19-26	dimethylglycine dehydrogenase	Homo sapiens	56-61
25935222-5	2015	For the recognition of each amino acid (here, serine, proline, glycine, asparagine, leucine, and histidine), the corresponding aminoacyl-tRNA synthetase (aaRS) was employed, and multiple enzymatic reactions were combined with a luminol chemiluminescence reaction.	Glycine	63-70	alanyl-tRNA synthetase 1	Homo sapiens	154-158
9391907-0	1997	Design, synthesis and conformational analysis of hGM-CSF(13-31)-Gly-Pro-Gly-(103-116).	Glycine	64-67	colony stimulating factor 2	Homo sapiens	49-56
9307096-0	1997	Potentiation of NMDA receptor-mediated responses by dynorphin at low extracellular glycine concentrations.	Glycine	83-90	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	16-29
9307096-11	1997	The observations are consistent with the potentiation of NMDA-activated current at low extracellular glycine concentrations resulting from an interaction of the glycine amino acids in dynorphin A(1-13) with the glycine coagonist site on the NMDA receptor.	Glycine	161-180	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	241-254
9307096-11	1997	The observations are consistent with the potentiation of NMDA-activated current at low extracellular glycine concentrations resulting from an interaction of the glycine amino acids in dynorphin A(1-13) with the glycine coagonist site on the NMDA receptor.	Glycine	161-168	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	241-254
24127292-3	2014	Previously, Val-Pro-Gly-Val-Gly peptides have been conjugated to a dendrimer for designing an elastin-mimetic dendrimer.	Glycine	20-23	elastin	Homo sapiens	94-101
9252108-3	1997	The majority of DPP IV isolated from total seminal plasma consists of the extracellular part of the protein starting at Gly-31.	Glycine	120-123	dipeptidyl peptidase 4	Homo sapiens	16-22
24127292-3	2014	Previously, Val-Pro-Gly-Val-Gly peptides have been conjugated to a dendrimer for designing an elastin-mimetic dendrimer.	Glycine	28-31	elastin	Homo sapiens	94-101
25765297-6	2015	Of 10 glycines present in the GxxxG motifs in the first, second and third transmembrane segments of Tim23, mutations of three of them in transmembrane segments 1 and 2 resulted in a lethal phenotype, and mutations of three others in a temperature-sensitive phenotype.	Glycine	6-14	translocase of inner mitochondrial membrane 23	Homo sapiens	100-105
9263462-2	1997	The predicted protein (RGP-3) is 144 amino acid residues long, and contains a consensus sequence-type RNA binding domain (CS-RBD) of 83 amino acids and a short glycine-rich region of 15 amino acids.	Glycine	160-167	glycine-rich RNA-binding protein 2, mitochondrial-like	Nicotiana tabacum	23-28
26136767-7	2015	Our in silico investigation suggests that, the glycine zipper motifs of C19orf12 form helical regions spanning the membrane.	Glycine	47-54	chromosome 19 open reading frame 12	Homo sapiens	72-80
24318965-4	2014	Gly-ir cells in rhombomeres 5 and 6 that also expressed glycine transporter 2 (glyt2) mRNA were highly stereotyped; they were bilaterally located and their axons ran across the midline and gradually turned caudally, joining the medial longitudinal fascicles in the spinal cord by 24 hpf.	Glycine	0-3	solute carrier family 6 member 5	Danio rerio	56-77
24318965-4	2014	Gly-ir cells in rhombomeres 5 and 6 that also expressed glycine transporter 2 (glyt2) mRNA were highly stereotyped; they were bilaterally located and their axons ran across the midline and gradually turned caudally, joining the medial longitudinal fascicles in the spinal cord by 24 hpf.	Glycine	0-3	solute carrier family 6 member 5	Danio rerio	79-84
23529192-1	2014	GlyT1 and GlyT2 are the transporters responsible for glycine uptake from the synaptic cleft.	Glycine	53-60	solute carrier family 6 member 9	Rattus norvegicus	0-5
23529192-6	2014	The functional characterization of GlyT1 and GlyT2 in cultured astrocytes performed by [(3)H]glycine uptake experiments revealed that both transporters take up glycine in a concentration-dependent way, but with a very distinct affinity.	Glycine	93-100	solute carrier family 6 member 9	Rattus norvegicus	35-40
23529192-6	2014	The functional characterization of GlyT1 and GlyT2 in cultured astrocytes performed by [(3)H]glycine uptake experiments revealed that both transporters take up glycine in a concentration-dependent way, but with a very distinct affinity.	Glycine	160-167	solute carrier family 6 member 9	Rattus norvegicus	35-40
25938568-2	2015	Eutherian mammals possess a highly conserved sequence of OXT (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly).	Glycine	94-97	oxytocin/neurophysin I prepropeptide	Homo sapiens	57-60
9199168-6	1997	Additionally, the unique (Gly-Leu)5 repeat located between the palmitoylation sites (Cys-15 and -26) of eNOS is necessary for its palmitoylation and thus localization, but not for N-myristoylation, membrane association, and NOS activity.	Glycine	26-29	nitric oxide synthase 3, endothelial cell	Mus musculus	104-108
25855294-0	2015	SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.	Glycine	75-82	serine hydroxymethyltransferase 2	Homo sapiens	0-5
24674276-5	2014	The synaptically induced plateau potential and the Ca2+ elevation were blocked by 5,7-dichlorokynurenic acid (5,7-dCK), an antagonist for the glycine-binding sites of NMDAR.	Glycine	142-149	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	114-117
9166417-11	1997	Because the dominant interference of glycine substitution mutations is maximal when type IV collagen secretion is totally blocked, this interference appears to occur intracellularly, rather than in the basement membrane.	Glycine	37-44	Col_cuticle_N domain-containing protein	Caenorhabditis elegans	92-100
24705540-3	2014	Typical SSB proteins have an N-terminal Oligonucleotide-Binding (OB) fold, a Proline/Glycine rich region, followed by a C-terminal acidic tail.	Glycine	85-92	single-stranded DNA-binding protein	Escherichia coli	8-11
25855294-5	2015	GLDC inhibition impairs cells with high SHMT2 levels as the excess glycine not metabolized by GLDC can be converted to the toxic molecules aminoacetone and methylglyoxal.	Glycine	67-74	serine hydroxymethyltransferase 2	Homo sapiens	40-45
25855294-6	2015	Thus, SHMT2 is required for cancer cells to adapt to the tumour environment, but also renders these cells sensitive to glycine cleavage system inhibition.	Glycine	119-126	serine hydroxymethyltransferase 2	Homo sapiens	6-11
25687964-8	2015	Thus, restoration of Sis1 in vitro activity suggests that intramolecular interactions between the J-domain and glycine-rich region control co-chaperone activity, which is optimal only when Sis1 interacts with the EEVD(Hsp70) motif.	Glycine	111-118	heat shock protein family A (Hsp70) member 4	Homo sapiens	218-223
9184147-11	1997	For substrates carrying a Gly at P2, binding of thrombomodulin changes the relative specificity of the slow and fast forms and makes the slow form more specific.	Glycine	26-29	thrombomodulin	Homo sapiens	48-62
25849507-8	2015	In this structure the glycine-rich P-loop is found in a relatively open conformation compared with other known ABL family-inhibitor complex structures.	Glycine	22-29	c-abl oncogene 1, non-receptor tyrosine kinase	Mus musculus	111-114
24519919-3	2014	The bio-activity of the fluorescent Gly-Ag NCs are further examined using GLUT-1 over-expressing cancer cells K562.	Glycine	36-39	solute carrier family 2 member 1	Homo sapiens	74-80
9177403-5	1997	Regression of pubertal development during anticonvulsive treatment with GABA agonists (loreclezole and vigabatrin) suggested that the stimulatory effects of glycine could be overcome by GABA receptor-mediated inhibition.	Glycine	157-164	GABA type A receptor-associated protein	Homo sapiens	186-199
24201779-8	2014	Conversely, an increased risk was observed for the glycine/arginine or arginine/arginine genotype of the adrenoceptor beta2, surface (ADRB2) gene rs1042713 as compared with the glycine/glycine genotype (odds ratio, 1.52 [95% confidence interval, 1.01-2.31]).	Glycine	51-58	adrenoceptor beta 2	Homo sapiens	105-132
24201779-8	2014	Conversely, an increased risk was observed for the glycine/arginine or arginine/arginine genotype of the adrenoceptor beta2, surface (ADRB2) gene rs1042713 as compared with the glycine/glycine genotype (odds ratio, 1.52 [95% confidence interval, 1.01-2.31]).	Glycine	51-58	adrenoceptor beta 2	Homo sapiens	134-139
24201779-8	2014	Conversely, an increased risk was observed for the glycine/arginine or arginine/arginine genotype of the adrenoceptor beta2, surface (ADRB2) gene rs1042713 as compared with the glycine/glycine genotype (odds ratio, 1.52 [95% confidence interval, 1.01-2.31]).	Glycine	177-184	adrenoceptor beta 2	Homo sapiens	105-132
24201779-8	2014	Conversely, an increased risk was observed for the glycine/arginine or arginine/arginine genotype of the adrenoceptor beta2, surface (ADRB2) gene rs1042713 as compared with the glycine/glycine genotype (odds ratio, 1.52 [95% confidence interval, 1.01-2.31]).	Glycine	177-184	adrenoceptor beta 2	Homo sapiens	134-139
24201779-8	2014	Conversely, an increased risk was observed for the glycine/arginine or arginine/arginine genotype of the adrenoceptor beta2, surface (ADRB2) gene rs1042713 as compared with the glycine/glycine genotype (odds ratio, 1.52 [95% confidence interval, 1.01-2.31]).	Glycine	177-184	adrenoceptor beta 2	Homo sapiens	105-132
24201779-8	2014	Conversely, an increased risk was observed for the glycine/arginine or arginine/arginine genotype of the adrenoceptor beta2, surface (ADRB2) gene rs1042713 as compared with the glycine/glycine genotype (odds ratio, 1.52 [95% confidence interval, 1.01-2.31]).	Glycine	177-184	adrenoceptor beta 2	Homo sapiens	134-139
24467211-2	2014	In humans, GLDC is part of a multienzyme complex (which includes the lipoyl-containing H-protein) that couples the decarboxylation of glycine to the biosynthesis of serine.	Glycine	134-141	myosin binding protein H	Homo sapiens	87-96
24297171-9	2014	Of the MMPs tested, MMP-2 and MMP-9 most greatly favored the presence of charged residues with preference for the Gly-Asp-Lys series.	Glycine	114-117	matrix metallopeptidase 9	Homo sapiens	30-35
25870547-8	2015	Using two Gpr101-Cre founder lines with different degrees of expression in the striatum, we conditionally deleted the vesicular inhibitory amino acid transporter (VIAAT), responsible for storage of GABA and glycine in synaptic vesicles.	Glycine	207-214	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	118-161
25870547-8	2015	Using two Gpr101-Cre founder lines with different degrees of expression in the striatum, we conditionally deleted the vesicular inhibitory amino acid transporter (VIAAT), responsible for storage of GABA and glycine in synaptic vesicles.	Glycine	207-214	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	163-168
9047300-1	1997	A 19-amino acid residue peptide, Gly-Trp-Leu-Lys-Ile-Lys-Ala-Ala-Met-Arg-Trp-Gly-Phe-Phe-Val-Arg-Lys-Lys- Ala, corresponding to the basic amphiphilic alpha-helix (BAA) motif at the C-terminus of a recombinant tobacco calmodulin-binding protein, TCB60, was synthesized.	Glycine	33-36	calmodulin-binding protein 60 B-like	Nicotiana tabacum	245-250
25474438-10	2015	Enzymatic assays with cathepsin B showed the release of CLB-Gly-OH from these sequences within a short time.	Glycine	60-66	cathepsin B	Homo sapiens	22-33
24297171-12	2014	More specifically, the lack of Gly-Asp-Lys clusters may diminish potential MMP-2 and MMP-9 collagenolytic activity.	Glycine	31-34	matrix metallopeptidase 9	Homo sapiens	85-90
9047300-1	1997	A 19-amino acid residue peptide, Gly-Trp-Leu-Lys-Ile-Lys-Ala-Ala-Met-Arg-Trp-Gly-Phe-Phe-Val-Arg-Lys-Lys- Ala, corresponding to the basic amphiphilic alpha-helix (BAA) motif at the C-terminus of a recombinant tobacco calmodulin-binding protein, TCB60, was synthesized.	Glycine	77-80	calmodulin-binding protein 60 B-like	Nicotiana tabacum	245-250
9030564-2	1997	The monooxygenase, PAM, first catalyzes conversion of a glycine-extended pro-peptide to the corresponding alpha-hydroxyglycine derivative, and the lyase, PGL, then catalyzes breakdown of this alpha-hydroxyglycine derivative to the amidated peptide plus glyoxylate.	Glycine	56-63	peptidylglycine alpha-amidating monooxygenase L homeolog	Xenopus laevis	19-22
24428873-1	2014	BACKGROUND: Hemoglobin Shepherds Bush (Human Genome Variation Society name: HBB:c.224G &gt; A) is an unstable hemoglobin variant resulting from a beta 74 GGC to GAC mutation (Gly to Asp) that manifests clinically as hemolytic anemia or gall bladder disease due to chronic subclinical hemolysis.	Glycine	175-178	gamma-glutamylcyclotransferase	Homo sapiens	154-157
25541374-6	2015	Some of the mutations prevented the stress-induced phosphorylation of eIF2alpha by all mammalian kinases, thus defining amino acid residues in eIF2alpha (Gly 30, Leu 50, and Asp 83) that are required for substrate recognition.	Glycine	154-157	eukaryotic translation initiation factor 2A	Homo sapiens	70-79
25541374-6	2015	Some of the mutations prevented the stress-induced phosphorylation of eIF2alpha by all mammalian kinases, thus defining amino acid residues in eIF2alpha (Gly 30, Leu 50, and Asp 83) that are required for substrate recognition.	Glycine	154-157	eukaryotic translation initiation factor 2A	Homo sapiens	143-152
9034004-2	1997	Several groups attempted to find an association between a serine-to-glycine polymorphism at codon 9 of the DRD3 gene (Ser9Gly) and schizophrenia; however, the results were inconsistent.	Glycine	68-75	dopamine receptor D3	Homo sapiens	107-111
25301276-1	2015	Inhibitory glycinergic neurotransmission is terminated by the specific glycine transporters GlyT1 and GlyT2 which actively reuptake glycine from the synaptic cleft.	Glycine	11-18	solute carrier family 6 member 5 S homeolog	Xenopus laevis	102-107
25301276-3	2015	GlyT2 is the main supplier of glycine for vesicle refilling, a process that is vital to preserve the quantal glycine content in synaptic vesicles.	Glycine	30-37	solute carrier family 6 member 5 S homeolog	Xenopus laevis	0-5
25301276-3	2015	GlyT2 is the main supplier of glycine for vesicle refilling, a process that is vital to preserve the quantal glycine content in synaptic vesicles.	Glycine	109-116	solute carrier family 6 member 5 S homeolog	Xenopus laevis	0-5
25483093-3	2014	Both Hsp90/Cdc37 chaperone and importin complexes associated with the N-terminal kinase domain of Gwl, whereas an intact glycine-rich loop at the N-terminus of Gwl was essential for binding of Hsp90/Cdc37 but not importins.	Glycine	121-128	microtubule associated serine/threonine kinase like L homeolog	Xenopus laevis	160-163
9089691-4	1997	The glycine site antagonists L-689,560 and 7-Cl-kynurenate were 10 times more potent at NR1A/NR2A than at NR1A/NR2B receptor subtypes.	Glycine	4-11	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	111-115
24419801-0	2014	Glycine/Serine polymorphism at position 38 influences KCNE1 subunit"s modulatory actions on rapid and slow delayed rectifier K+ currents.	Glycine	0-7	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	54-59
24419801-3	2014	There are major and minor polymorphismic KCNE1 variants whose 38(th) amino acids are glycine and serine [KCNE1(38G) and KCNE1(38S) subunits], respectively.	Glycine	85-92	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	41-46
24419801-3	2014	There are major and minor polymorphismic KCNE1 variants whose 38(th) amino acids are glycine and serine [KCNE1(38G) and KCNE1(38S) subunits], respectively.	Glycine	85-92	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	105-110
24419801-3	2014	There are major and minor polymorphismic KCNE1 variants whose 38(th) amino acids are glycine and serine [KCNE1(38G) and KCNE1(38S) subunits], respectively.	Glycine	85-92	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	105-110
25471371-4	2015	Replacement of Gln-105-Ser-106-Gly-107 in the acidic loop of Ube2r1C (Ube2r1C(YGY)) by the corresponding residues from Ube2g1 (Tyr-102-Gly-103-Tyr-104) increased Lys-48-ubiquitylation activity and ubiquitin binding.	Glycine	135-138	ubiquitin conjugating enzyme E2 G1	Homo sapiens	119-125
25568082-5	2015	During T-cell activation, signal transduction through the phosphoinositide-3 kinase-RAC-alpha serine/threonine-protein kinase-mechanistic target of rapamycin pathway increased the assembly of microRNAs into HMW-RISC, enhanced expression of the glycine-tryptophan protein of 182 kDa, an essential component of HMW-RISC, and improved the ability of microRNAs to repress partially complementary reporters, even when expression of targeting microRNAs did not increase.	Glycine	244-251	serine carboxypeptidase 1	Homo sapiens	211-215
9044450-1	1997	Glycine has been shown to protect against cisplatin (CP) nephrotoxicity in rats and to enhance the in vitro expression of heat-shock protein (hsp) 70 in renal epithelial cells following sublethal heat shock.	Glycine	0-7	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	122-149
25568082-5	2015	During T-cell activation, signal transduction through the phosphoinositide-3 kinase-RAC-alpha serine/threonine-protein kinase-mechanistic target of rapamycin pathway increased the assembly of microRNAs into HMW-RISC, enhanced expression of the glycine-tryptophan protein of 182 kDa, an essential component of HMW-RISC, and improved the ability of microRNAs to repress partially complementary reporters, even when expression of targeting microRNAs did not increase.	Glycine	244-251	serine carboxypeptidase 1	Homo sapiens	313-317
22339171-3	2014	In our previous paper we showed that the MMP-9 enzyme recognizes a specific peptide sequence, Lys-Gly- Pro-Arg-Ser-Leu-Ser-Gly-Lys, and cleaves the peptide into two parts [1].	Glycine	98-101	matrix metallopeptidase 9	Homo sapiens	41-46
22339171-3	2014	In our previous paper we showed that the MMP-9 enzyme recognizes a specific peptide sequence, Lys-Gly- Pro-Arg-Ser-Leu-Ser-Gly-Lys, and cleaves the peptide into two parts [1].	Glycine	123-126	matrix metallopeptidase 9	Homo sapiens	41-46
9044450-2	1997	We hypothesized that the protective effect of glycine against CP nephrotoxicity may be due to an up-regulation of Hsp 70 protein expression.	Glycine	46-53	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	114-120
25550512-6	2015	During postnatal development, the replacement of GluN2B- by GluN2A-containing NMDARs at SC-CA1 synapses parallels a change in the identity of the coagonist from glycine to D-serine.	Glycine	161-168	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	49-55
24268404-4	2014	These proteases cleave OPN at several positions near the integrin-binding sequence Arg-Gly-Asp(138).	Glycine	87-90	secreted phosphoprotein 1	Bos taurus	23-26
9044450-9	1997	Animals receiving CP and glycine demonstrated a more focal presence of Hsp 70 restricted to injured proximal tubular cells, with no staining of uninjured cells.	Glycine	25-32	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	71-77
23968838-7	2015	Importantly, we demonstrate that treatment with NMDAR co-agonists (glycine or D-serine) independently rescue impairments in NMDAR-dependent synaptic plasticity in the DG of the Fragile X mental retardation 1 (Fmr1) knockout mouse.	Glycine	67-74	fragile X messenger ribonucleoprotein 1	Mus musculus	177-207
23968838-7	2015	Importantly, we demonstrate that treatment with NMDAR co-agonists (glycine or D-serine) independently rescue impairments in NMDAR-dependent synaptic plasticity in the DG of the Fragile X mental retardation 1 (Fmr1) knockout mouse.	Glycine	67-74	fragile X messenger ribonucleoprotein 1	Mus musculus	209-213
9392053-8	1997	Codon 12 point mutation of c-Ha-ras (GGC--&gt;GTC; Gly--&gt;Val) was detected in T24 (grade III, epidermoid, superficial) through single-strand conformation polymorphism, and sequencing analysis.	Glycine	51-54	transcription factor like 5	Homo sapiens	27-31
25731620-8	2015	In conditions involving down regulated GSH homeostasis, GGC serves as a crucialrate-limiting substrate for GSH synthetase, the main enzyme responsible for condensing glycine with GGC to form the final thiol tripeptide, GSH.	Glycine	166-173	gamma-glutamylcyclotransferase	Homo sapiens	56-59
25731620-8	2015	In conditions involving down regulated GSH homeostasis, GGC serves as a crucialrate-limiting substrate for GSH synthetase, the main enzyme responsible for condensing glycine with GGC to form the final thiol tripeptide, GSH.	Glycine	166-173	gamma-glutamylcyclotransferase	Homo sapiens	179-182
24316826-2	2013	In a previous report, it was shown that MK2 in complex with the selective inhibitor TEI-I01800 adopts an alpha-helical glycine-rich loop that is induced by the stable nonplanar conformer of TEI-I01800.	Glycine	119-126	MAPK activated protein kinase 2	Homo sapiens	40-43
24316826-4	2013	MK2-TEI-L03090 has a beta-sheet glycine-rich loop in common with other kinases, as predicted.	Glycine	32-39	MAPK activated protein kinase 2	Homo sapiens	0-3
25253739-4	2014	Interestingly, bioactive mouse GDF9 and human BMP15 share the conserved arginine in the pre-helix loop, but their low-activity counterparts (mouse BMP15 and human GDF9) have a glycine or a proline instead.	Glycine	176-183	bone morphogenetic protein 15	Mus musculus	147-152
8955083-6	1996	The unitary glutamate receptor has a unique set of properties that denote intersubunit interaction, including a glycine requirement for the responses to non-NMDA as well as to NMDA receptor agonists and voltage-dependent block by Mg2+ of the non-NMDA agonist responses.	Glycine	112-119	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	176-189
25160622-9	2014	A second effector site position, Gly-149 in AtCM1 and Asp-132 in AtCM3, controls amino acid effector specificity in AtCM1 and AtCM3.	Glycine	33-36	chorismate mutase 3	Arabidopsis thaliana	65-70
25160622-9	2014	A second effector site position, Gly-149 in AtCM1 and Asp-132 in AtCM3, controls amino acid effector specificity in AtCM1 and AtCM3.	Glycine	33-36	chorismate mutase 3	Arabidopsis thaliana	126-131
24206140-2	2013	In the last decades, a series of radiolabeled Arg-Gly-Asp (RGD) peptides targeting integrin alphavbeta3 has been prepared and optimized for positron emission tomography (PET) and single-photon-emission computed tomography (SPECT) imaging of integrin alphavbeta3 expression.	Glycine	50-53	integrin subunit alpha V	Homo sapiens	83-103
8943222-1	1996	A constitutively activating mutation encoding Asp578--&gt;Gly in transmembrane helix 6 of the lutropin/choriogonadotropin receptor (LHR) is the most common cause of gonadotropin-independent, male-limited precocious puberty.	Glycine	58-61	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	94-130
24121506-5	2013	Within L1C domains, five amino acid residues (Leu-135, Gly-188, Arg-244, and vicinal His-318 and Lys-319) were identified as IRR-specific by species conservation analysis of the IR family.	Glycine	55-58	insulin receptor related receptor	Homo sapiens	125-128
25251471-6	2014	Truncation of the glycine-rich domain reduces the binding affinity of AtGRP7, showing for the first time that the glycine-rich stretch of a plant hnRNP-like protein contributes to binding.	Glycine	18-25	cold, circadian rhythm, and rna binding 2	Arabidopsis thaliana	70-76
25251471-6	2014	Truncation of the glycine-rich domain reduces the binding affinity of AtGRP7, showing for the first time that the glycine-rich stretch of a plant hnRNP-like protein contributes to binding.	Glycine	114-121	cold, circadian rhythm, and rna binding 2	Arabidopsis thaliana	70-76
25961277-6	2013	In addition, we found the glycine-rich regions in Hoxc13 protein in mammals, but not among non-mammalian taxa.	Glycine	26-33	homeobox C13	Homo sapiens	50-56
24273285-6	2013	CONCLUSION: GLY can cause cellular damages, inhibit cell proliferation, induce cell apoptosis, and decrease expression of ABP and vimentin mRNAs in mouse Sertoli cells in vitro.	Glycine	12-15	vimentin	Mus musculus	130-138
8943222-1	1996	A constitutively activating mutation encoding Asp578--&gt;Gly in transmembrane helix 6 of the lutropin/choriogonadotropin receptor (LHR) is the most common cause of gonadotropin-independent, male-limited precocious puberty.	Glycine	58-61	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	132-135
9010776-7	1996	We isolated a candidate cDNA for ABP-2, and the protein it encoded contained nine Zn fingers and regions rich in alanine, glutamine, serine/threonine, glycine, histidine, and asparagine.	Glycine	151-158	lava lamp	Drosophila melanogaster	33-38
26309287-1	2014	Wild Mediterranean fruit fly specimens collected from various regions worldwide were screened for the glycine to alanine (Gly-&gt;Ala) point mutation (G328A) in the acetylcholinesterase enzyme, presumably causing resistance to organophosphates.	Glycine	102-109	acetylcholinesterase-like	Ceratitis capitata	165-185
26309287-1	2014	Wild Mediterranean fruit fly specimens collected from various regions worldwide were screened for the glycine to alanine (Gly-&gt;Ala) point mutation (G328A) in the acetylcholinesterase enzyme, presumably causing resistance to organophosphates.	Glycine	122-125	acetylcholinesterase-like	Ceratitis capitata	165-185
9048488-2	1996	Five tumors were found to harbor H-ras mutations where two tumors had a glycine to valine (G--&gt;T) change in codon 12 and three tumors had a glutamine to lysine (C--&gt;A) change in codon 61, respectively.	Glycine	72-79	HRas proto-oncogene, GTPase	Homo sapiens	33-38
8947046-4	1996	TGF-beta1 induced in vivo phosphorylation of serine and threonine residues in the juxtamembrane domain of TbetaR-I in a region rich in glycine, serine and threonine residues (GS domain; Thr185, Thr186, Ser187, Ser189 and Ser191), and more N-terminal of this region (Ser165).	Glycine	135-142	transforming growth factor beta receptor 1	Homo sapiens	106-114
25223783-2	2014	To further explore potentials of RNAi technology as therapeutics, we engineered and tested VEGFR2 siRNA molecules specifically targeted to tumors through covalently conjugated cyclo(Arg-Gly-Asp-d-Phe-Lys[PEG-MAL]) (cRGD) peptide, known to bind alphavbeta3 integrin receptors.	Glycine	186-189	kinase insert domain receptor	Homo sapiens	91-97
25181299-3	2014	The carboxyl termini of mammalian Atg8 homologs are cleaved by Atg4B, a cysteine protease, to expose carboxyl terminal Gly which is essential for this ubiquitylation-like reaction.	Glycine	119-122	GABA type A receptor associated protein like 2	Homo sapiens	34-38
8810903-2	1996	The crystal structure of GNMT complexed with AdoMet and acetate, a competitive inhibitor of glycine, has been determined at 2.2 A resolution.	Glycine	92-99	glycine N-methyltransferase	Rattus norvegicus	25-29
8872472-5	1996	We identified a novel missense mutation in two unrelated families which substitutes a serine for a conserved glycine in the putative pore region of the KVLQT1 channel.	Glycine	109-116	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	152-158
25184293-6	2014	Candidate gene sequencing identified a G&gt;C transversion at position 5731 of CACNA1C (rs374528680) predicting a glycine&gt;arginine substitution at residue 1911 (p.G1911R) of CaV1.2.	Glycine	114-121	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	79-86
25184293-6	2014	Candidate gene sequencing identified a G&gt;C transversion at position 5731 of CACNA1C (rs374528680) predicting a glycine&gt;arginine substitution at residue 1911 (p.G1911R) of CaV1.2.	Glycine	114-121	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	177-183
8704259-2	1996	Although the enzymatic activity of the c-kit product (KIT) is regulated by its ligand, both the Val559--&gt;Gly (G559) mutation in the juxtamembrane domain and the Asp814--&gt;Val (V814) mutation in the phosphotransferase domain lead to constitutive activation of KIT.	Glycine	108-111	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	39-44
25133088-9	2014	Moreover, there are important evolutional mutations that can change the conformation of the proteins, for instance, hydrophilic N139 changed to hydrophobic Gly (mPTP1B); E132 to proline in the hydrophobic core structure or Y46 to cystein in pTyr recognition loop.	Glycine	156-159	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	161-167
8704259-2	1996	Although the enzymatic activity of the c-kit product (KIT) is regulated by its ligand, both the Val559--&gt;Gly (G559) mutation in the juxtamembrane domain and the Asp814--&gt;Val (V814) mutation in the phosphotransferase domain lead to constitutive activation of KIT.	Glycine	108-111	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	54-57
25057202-5	2014	Blockade of GlyT1 also caused a profound increase in the baseline current induced by exogenous glycine.	Glycine	95-102	solute carrier family 6 member 9	Rattus norvegicus	12-17
8764403-0	1996	NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone.	Glycine	38-41	DnaJ	Escherichia coli	82-86
24838244-6	2014	Using a combination of pharmacological, biochemical, and computational approaches, we found that Phe-203(3.40) and Gly-210(3.47) in TM3 play an important role in receptor activation.	Glycine	115-118	tropomyosin 3	Homo sapiens	132-135
8764403-1	1996	The recombinant N-terminal 107-amino acid polypeptide fragment 2-108 of the DnaJ molecular chaperone of Escherichia coli, which contains the J-domain (residues 2 to 76) and the Gly/Phe-rich region (residues 77 to 108), was uniformly labeled with nitrogen-15 and carbon-13.	Glycine	177-180	DnaJ	Escherichia coli	76-80
8764403-12	1996	Considering that this same segment shows sequence conservation with corresponding segments in the Gly/Phe-rich regions of other DnaJ-like proteins, its reduced flexibility may be directly linked to the formation of the ternary DnaJ-DnaK-polypeptide complex.	Glycine	98-101	DnaJ	Escherichia coli	128-132
24978476-8	2014	When ERRgamma-Asn346 was replaced by the corresponding Gly and Tyr in ERRalpha and ERRbeta, respectively, the binding affinity of BPA and even 4-hydroxytamxifen (4-OHT) is much reduced.	Glycine	55-58	estrogen related receptor beta	Homo sapiens	83-90
8764403-12	1996	Considering that this same segment shows sequence conservation with corresponding segments in the Gly/Phe-rich regions of other DnaJ-like proteins, its reduced flexibility may be directly linked to the formation of the ternary DnaJ-DnaK-polypeptide complex.	Glycine	98-101	DnaJ	Escherichia coli	227-231
8650234-7	1996	The presence of the unusual conserved Cys-Secys-Gly sequence at the C terminus of TR in addition to the redox active cysteines of the Cys-Val-Asn-Val-Gly-Cys motif in the FAD-binding region may account for the peroxidase activity and the relatively low substrate specificity of mammalian TRs.	Glycine	48-51	peroxiredoxin 5	Homo sapiens	82-84
24616110-1	2014	A novel antimicrobial peptide, designated macropin (MAC-1) with sequence Gly-Phe-Gly-Met-Ala-Leu-Lys-Leu-Leu-Lys-Lys-Val-Leu-NH2 , was isolated from the venom of the solitary bee Macropis fulvipes.	Glycine	73-76	integrin subunit alpha M	Homo sapiens	52-57
8650234-7	1996	The presence of the unusual conserved Cys-Secys-Gly sequence at the C terminus of TR in addition to the redox active cysteines of the Cys-Val-Asn-Val-Gly-Cys motif in the FAD-binding region may account for the peroxidase activity and the relatively low substrate specificity of mammalian TRs.	Glycine	150-153	peroxiredoxin 5	Homo sapiens	82-84
8654369-7	1996	The HSCR972 (Arg972--&gt;Gly) mutation, mapping in the intracytoplasmic region of RET, impaired its tyrosine kinase activity, while two extracellular mutations, HSCR32 (Ser32--&gt;Leu) and HSCR393 (Phe393--&gt;Leu), inhibited the biological activity of RET by impairing the correct maturation of the RET protein and its transport to the cell surface.	Glycine	25-28	ret proto-oncogene	Homo sapiens	82-85
24733396-3	2014	Our study revealed that the isolated transmembrane domain (TMD) of EphA2 embedded into the lipid bicelle dimerized via the heptad repeat motif L(535)X3G(539)X2A(542)X3V(546)X2L(549) rather than through the alternative glycine zipper motif A(536)X3G(540)X3G(544) (typical for TMD dimerization in many proteins).	Glycine	218-225	EPH receptor A2	Homo sapiens	67-72
24733396-11	2014	These findings allow us to suggest TMD dimerization switching between the heptad repeat and glycine zipper motifs, corresponding to inactive and active receptor states, respectively, as a mechanism underlying EphA2 signal transduction.	Glycine	92-99	EPH receptor A2	Homo sapiens	209-214
24844639-11	2014	The polymorphisms resulting in Arg/Arg and Gly/Gly at position 16 of the beta2-adrenergic receptor do not result in clinically meaningful differences in lipolysis responses to epinephrine or submaximal exercise.	Glycine	47-50	adrenoceptor beta 2	Homo sapiens	73-98
24627494-3	2014	We explored the hypothesis that a conserved His-rich cluster (His-Gly-His-His) in the linker region connecting its two catalytic domains senses pH and affects PAM trafficking by mutating these His residues to Ala (Ala-Gly-Ala-Ala; H3A).	Glycine	66-69	zinc finger protein 106	Mus musculus	231-234
24601881-9	2014	Induction of the SMAD2/3 pathway by ALK3 is dependent upon its own previous activation by associated type II receptors, which phosphorylate conserved serine and threonine residues in the ALK3 juxtamembrane glycine-serine-rich domain.	Glycine	206-213	bone morphogenetic protein receptor, type 1A	Mus musculus	36-40
24601881-9	2014	Induction of the SMAD2/3 pathway by ALK3 is dependent upon its own previous activation by associated type II receptors, which phosphorylate conserved serine and threonine residues in the ALK3 juxtamembrane glycine-serine-rich domain.	Glycine	206-213	bone morphogenetic protein receptor, type 1A	Mus musculus	187-191
24553751-6	2014	tmm-6 mutation took a base transition from guanine to adenine in 463 of TMM and changed a glycine (Gly) to an arginine (Arg) in position 155 of the protein.	Glycine	90-97	Leucine-rich repeat (LRR) family protein	Arabidopsis thaliana	0-3
24553751-6	2014	tmm-6 mutation took a base transition from guanine to adenine in 463 of TMM and changed a glycine (Gly) to an arginine (Arg) in position 155 of the protein.	Glycine	99-102	Leucine-rich repeat (LRR) family protein	Arabidopsis thaliana	0-3
24700805-9	2014	We demonstrated that reduced AGL enhances tumor growth by increasing glycine synthesis through increased expression of serine hydroxymethyltransferase 2.	Glycine	69-76	serine hydroxymethyltransferase 2	Homo sapiens	119-152
24778717-4	2014	The most ordered conformation was found for peptide Boc-Gly-DeltaAla-Gly-Delta(Z)Phe-Val-OMe (3), which adopts a right-handed helical conformation.	Glycine	56-59	BOC cell adhesion associated, oncogene regulated	Homo sapiens	52-55
24388924-3	2014	While the activity of the secondary active, K(+)-Cl(-)-extruding cotransporter KCC2, renders GABA/glycine hyperpolarizing in auditory brainstem nuclei of altricial rodents, the mechanisms contributing to the initially depolarizing transmembrane gradient for Cl(-) in respective neurons remained unknown.	Glycine	98-105	solute carrier family 12 member 5	Homo sapiens	79-83
24606937-4	2014	This variability reflects a high flexibility for two regions of CK2alpha: the interdomain hinge region, and the glycine-rich loop (p-loop).	Glycine	112-119	casein kinase 2 alpha 2	Homo sapiens	64-72
23796630-2	2014	Carboxymethyl dextran-coated ultrasmall superparamagnetic iron oxide nanoparticles with carboxyl groups were coupled to cyclic arginine-glycine-aspartic peptides for integrin alpha(v)beta3 targeting.	Glycine	136-143	integrin subunit alpha V	Homo sapiens	166-188
24273061-8	2014	The glycine effect was insensitive to strychnine or to 5,7-dichlorokynurenate but it was abolished when GlyT2 transporters were blocked.	Glycine	4-11	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	104-109
24273061-11	2014	Na+ ions, reaching the cytosol during glycine uptake through GlyT2, activated mitochondrial Na+/Ca2+ exchangers, causing an increase in cytosolic Ca2+, which in turn triggered a Ca(2+)-induced Ca2+ release process at inositoltrisphosphate receptors.	Glycine	38-45	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	61-66
24273061-13	2014	In conclusion, GlyT2 transporters not only take up glycine to replenish synaptic vesicles but can also mediate release of GABA by reversal of GAT1 and permeation through anion channels.	Glycine	51-58	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	15-20
24852854-4	2014	KRAS codon 12 Gly Asp, Gly, Val, and codon 13 Gly Cys gene mutations were tested using an in-house real-time ARMS PCR method.	Glycine	14-17	KRAS proto-oncogene, GTPase	Homo sapiens	0-4
24328955-8	2014	Glycine conjugates of native and isomeric BAs were subjected to molecular dynamics simulations to identify topological descriptors related to binding and translocation by hASBT.	Glycine	0-7	solute carrier family 10 member 2	Homo sapiens	171-176
24510571-5	2014	HQ873871) has differed from HLA-B*33:03:01 by one nucleotide in exon 4, which resulted in nt 866 G  A substitution, which results in an amino acid substitution from Gly(GGT) to Asp(GAT) at codon 265.	Glycine	165-168	glycine-N-acyltransferase	Homo sapiens	181-184
24138715-9	2014	Keeping in mind that the glycine present at position 12 can be substituted by valine, aspartic acid or cysteine, it could be well understood that each different substitution plays a different role in K-RAS-dependent processes.	Glycine	25-32	KRAS proto-oncogene, GTPase	Homo sapiens	200-205
24125732-8	2013	Using sera from hnRNP L-positive patients, we found that most of these antibodies recognized glycine-rich region in the N-terminus of hnRNP L.	Glycine	93-100	heterogeneous nuclear ribonucleoprotein L	Homo sapiens	16-23
24125732-8	2013	Using sera from hnRNP L-positive patients, we found that most of these antibodies recognized glycine-rich region in the N-terminus of hnRNP L.	Glycine	93-100	heterogeneous nuclear ribonucleoprotein L	Homo sapiens	134-141
24125732-15	2013	Glycine-rich region located at the N-terminus of hnRNP L constitutes the major epitope.	Glycine	0-7	heterogeneous nuclear ribonucleoprotein L	Homo sapiens	49-56
24259588-9	2013	Using the glycine-induced, NMDA-dependent form of chemical long-term potentiation (LTP) in cultured cortical neurons, we showed that CD3zeta was required for activity-dependent CaMKII autophosphorylation and for the synaptic recruitment of the AMPAR subunit GluA1.	Glycine	10-17	calcium/calmodulin-dependent protein kinase II, beta	Mus musculus	177-183
23648839-0	2013	Three-dimensional structure of CAP-gly domain of mammalian dynactin determined by magic angle spinning NMR spectroscopy: conformational plasticity and interactions with end-binding protein EB1.	Glycine	35-38	microtubule associated protein RP/EB family member 1	Homo sapiens	189-192
23648839-5	2013	Upon binding of CAP-Gly to microtubule plus-end tracking protein EB1, the CAP-Gly shifts to a single conformer.	Glycine	20-23	microtubule associated protein RP/EB family member 1	Homo sapiens	65-68
23648839-5	2013	Upon binding of CAP-Gly to microtubule plus-end tracking protein EB1, the CAP-Gly shifts to a single conformer.	Glycine	78-81	microtubule associated protein RP/EB family member 1	Homo sapiens	65-68
23648839-6	2013	We find extensive chemical shift perturbations in several stretches of residues of CAP-Gly upon binding to EB1, from which we define accurately the CAP-Gly/EB1 binding interface.	Glycine	87-90	microtubule associated protein RP/EB family member 1	Homo sapiens	107-110
23648839-6	2013	We find extensive chemical shift perturbations in several stretches of residues of CAP-Gly upon binding to EB1, from which we define accurately the CAP-Gly/EB1 binding interface.	Glycine	87-90	microtubule associated protein RP/EB family member 1	Homo sapiens	156-159
23648839-6	2013	We find extensive chemical shift perturbations in several stretches of residues of CAP-Gly upon binding to EB1, from which we define accurately the CAP-Gly/EB1 binding interface.	Glycine	152-155	microtubule associated protein RP/EB family member 1	Homo sapiens	107-110
23648839-6	2013	We find extensive chemical shift perturbations in several stretches of residues of CAP-Gly upon binding to EB1, from which we define accurately the CAP-Gly/EB1 binding interface.	Glycine	152-155	microtubule associated protein RP/EB family member 1	Homo sapiens	156-159
23979192-5	2013	We studied the biophysical properties of an Ala-to-Gly substitution (A1529G) in rat Nav1.4 channel expressed in Xenopus oocytes alone or with a beta1 subunit.	Glycine	51-54	sodium voltage-gated channel alpha subunit 4	Rattus norvegicus	84-90
23650932-0	2013	Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.	Glycine	0-7	glycine-N-acyltransferase	Homo sapiens	59-84
23650932-1	2013	INTRODUCTION: Glycine conjugation of mitochondrial acyl-CoAs, catalyzed by glycine N-acyltransferase (GLYAT, E.C.	Glycine	14-21	glycine-N-acyltransferase	Homo sapiens	75-100
23650932-1	2013	INTRODUCTION: Glycine conjugation of mitochondrial acyl-CoAs, catalyzed by glycine N-acyltransferase (GLYAT, E.C.	Glycine	14-21	glycine-N-acyltransferase	Homo sapiens	102-107
23650932-6	2013	They focus on GLYAT, glycine conjugation, how genetic variation in the GLYAT gene could influence glycine conjugation, and the emerging roles of glycine metabolism in cancer and musculoskeletal development.	Glycine	98-105	glycine-N-acyltransferase	Homo sapiens	71-76
23650932-6	2013	They focus on GLYAT, glycine conjugation, how genetic variation in the GLYAT gene could influence glycine conjugation, and the emerging roles of glycine metabolism in cancer and musculoskeletal development.	Glycine	98-105	glycine-N-acyltransferase	Homo sapiens	71-76
23650932-7	2013	EXPERT OPINION: The substrate selectivity of GLYAT and its variants needs to be further characterized, as organic acids can be toxic if the corresponding acyl-CoA is not a substrate for glycine conjugation.	Glycine	186-193	glycine-N-acyltransferase	Homo sapiens	45-50
23650932-8	2013	GLYAT activity affects mitochondrial ATP production, glycine availability, CoASH availability, and the toxicity of various organic acids.	Glycine	53-60	glycine-N-acyltransferase	Homo sapiens	0-5
23986260-2	2013	GlyT2 is the main supplier of glycine for vesicle refilling, a process that is absolutely necessary to preserve quantal glycine content in synaptic vesicles.	Glycine	30-37	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	0-5
23986260-2	2013	GlyT2 is the main supplier of glycine for vesicle refilling, a process that is absolutely necessary to preserve quantal glycine content in synaptic vesicles.	Glycine	120-127	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	0-5
23986260-6	2013	GlyT2 cotransports 3Na+/Cl-/glycine generating large rises of Na+ inside the presynaptic terminal that must be efficiently reduced by the NKA to preserve Na+ homeostasis.	Glycine	28-35	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	0-5
23624125-3	2013	In this study, a novel heterozygous nucleotide G&gt;T transition at position 6101 in exon 73 of COL7A1 was detected, which resulted in a glycine to valine substitution (G2034V) in the triple-helical domain of type-VII collagen.	Glycine	137-144	collagen type VII alpha 1 chain	Homo sapiens	96-102
23549681-4	2013	However, in MDA-MB-231 cells (expressing high prolidase activity) cultured in the presence of prolidase substrates, Gly-Pro or Gly-HyPro, HIF-1alpha expression was induced in a dose-dependent manner, independently of estrogen receptor activation.	Glycine	116-119	peptidase D	Homo sapiens	46-55
23549681-4	2013	However, in MDA-MB-231 cells (expressing high prolidase activity) cultured in the presence of prolidase substrates, Gly-Pro or Gly-HyPro, HIF-1alpha expression was induced in a dose-dependent manner, independently of estrogen receptor activation.	Glycine	116-119	peptidase D	Homo sapiens	94-103
23389291-4	2013	The cleavage sites in RXRalpha were mapped by Edman N-terminal sequencing to Gly(90) Ser(91) and Lys(118) Val(119).	Glycine	77-80	retinoid X receptor alpha	Homo sapiens	22-30
23572558-2	2013	Classic fibrodysplasia ossificans progressiva (FOP) is a congenital syndrome resulting from highly conserved activating mutations of the glycine-serine-rich (GS) regulatory domain of ACVR1, encoding bone morphogenetic protein (BMP) type I receptor ALK2, which lead to inappropriate signaling and heterotopic ossification of soft tissues.	Glycine	137-144	activin A receptor, type 1	Mus musculus	183-188
23572558-2	2013	Classic fibrodysplasia ossificans progressiva (FOP) is a congenital syndrome resulting from highly conserved activating mutations of the glycine-serine-rich (GS) regulatory domain of ACVR1, encoding bone morphogenetic protein (BMP) type I receptor ALK2, which lead to inappropriate signaling and heterotopic ossification of soft tissues.	Glycine	137-144	activin A receptor, type 1	Mus musculus	248-252
23651498-2	2013	Integrin alphavbeta3 can be imaged with arginine-glycine-aspartic acid (RGD) peptide agents.	Glycine	49-56	integrin subunit alpha V	Homo sapiens	0-20
8799825-7	1996	Cell-binding fibronectin fragments (type III repeats 6-10) containing the Arg-Gly-Asp (RGD) sequence blocked both nodule initiation and maturation, whether or not they contained a functional synergy site.	Glycine	78-81	fibronectin 1	Rattus norvegicus	13-24
23447534-6	2013	Interestingly, the channel activities of Orai1 mutants carrying either an N-terminal or a C-terminal truncation were restored by a methionine mutation at the putative gating hinge, the conserved Gly-98 site in the first transmembrane segment (TM1) of Orai1.	Glycine	195-198	ORAI calcium release-activated calcium modulator 1	Homo sapiens	41-46
24121745-9	2013	In order to demonstrate the feasibility of the LC-MS/MS method, we measured glycine levels in striatal in vivo microdialysates and CSF of rats after administration of the commercially available glycine transporter 1 (GlyT1) inhibitor LY 2365109 (10mg/kg, p.o.).	Glycine	76-83	solute carrier family 6 member 9	Rattus norvegicus	217-222
23660505-7	2013	Functional activity of PEPT1 in colonic tissues from mice was assessed in everted sac preparations using [14C]Gly-Sar and found to be 5.7-fold higher in distal compared with proximal colon.	Glycine	110-113	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	23-28
8658052-9	1996	Because in the antigen-stimulated acute infection spleen or granuloma cultures the co-stimulatory effect by FN was abrogated by the tripeptide (RGD) arg-gly asp, and anti alpha 5 beta 1 antibody, enhancement is attributed to signalling via the alpha 5 beta 1 integrin receptor of lymphocytes.	Glycine	153-156	fibronectin 1	Mus musculus	108-110
23785729-5	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Mus musculus	31-42
23430410-8	2013	The activities of dehydroascorbate reductase (DHAR) and glyoxalase I (Gly I) decreased at any levels of As, while glutathione peroxidase (GPX) and glyoxalase II (Gly II) activities decreased only upon 0.5 mM As.	Glycine	70-73	probable glutathione S-transferase DHAR1, cytosolic	Triticum aestivum	18-44
23423386-2	2013	This method for the selective C-3 functionalization of unprotected indoles with the chiral equivalent of a nucleophilic glycine nickel(II) complex afforded adducts with high diastereoselectivities.	Glycine	120-127	complement C3	Homo sapiens	30-33
8651283-0	1996	A GLRA1 null mutation in recessive hyperekplexia challenges the functional role of glycine receptors.	Glycine	83-90	glycine receptor alpha 1	Homo sapiens	2-7
23397949-0	2013	Four novel and two recurrent glycine substitution mutations in the COL7A1 gene in Chinese patients with epidermolysis bullosa pruriginosa.	Glycine	29-36	collagen type VII alpha 1 chain	Homo sapiens	67-73
8929826-2	1996	A relatively common LPL variant results from a C --&gt; G transversion in exon 9, which creates a premature termination codon (S447X) and results in a truncated LPL molecule lacking the C-terminal dipeptide Ser-Gly.	Glycine	211-214	lipoprotein lipase	Homo sapiens	20-23
23452855-3	2013	Cloning of a short-period circadian mutant, Past-time, revealed a glycine to glutamate missense mutation in Fbxl21, an F-box protein gene that is a paralog of Fbxl3 that targets the CRY proteins for degradation.	Glycine	66-73	F-box and leucine rich repeat protein 3	Homo sapiens	159-164
8929826-2	1996	A relatively common LPL variant results from a C --&gt; G transversion in exon 9, which creates a premature termination codon (S447X) and results in a truncated LPL molecule lacking the C-terminal dipeptide Ser-Gly.	Glycine	211-214	lipoprotein lipase	Homo sapiens	161-164
23151080-2	2013	However, the contribution of NR2A and NR2B subunits in glycine-induced long-term potentiation (LTP) of miniature excitatory postsynaptic currents (mEPSCs) in layer II/III pyramidal neurons of the rat visual cortex remains unclear.	Glycine	55-62	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	38-42
23746511-6	2013	The results demonstrate that the CaV1.2 PL is more flexible than the CaV2.2 PL, the flexibility is intrinsic and not dependent on CaVbeta binding, and the flexibility can be most easily explained by the presence of conserved glycines.	Glycine	225-233	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	33-39
23151080-8	2013	These results suggest that the glycine-induced LTP in layer II/III pyramidal neurons of the rat visual cortex is NMDA-R-dependent and requires NR2A-containing NMDA-Rs, not NR2B-containing NMDA-Rs.	Glycine	31-38	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	172-176
8745435-0	1996	Hb J-Baltimore [beta 16(A13)Gly--&gt;Asp] associated with beta(+)-thalassemia in a Spanish family.	Glycine	28-31	immunoglobulin kappa variable 2D-18 (pseudogene)	Homo sapiens	24-27
23247335-2	2013	Peptidylglycine alpha-hydroxylating monooxygenase (PHM) performs the first step of the amidation reaction-the hydroxylation of peptidylglycine substrates at the Calpha position of the terminal glycine.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	51-54
23720861-16	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Homo sapiens	31-42
8830251-2	1996	The Saccharomyces cerevisiae GCV2 gene, encoding the P-protein has been cloned by complementation of the gsd2 mutation which prevents cells converting glycine to serine or using glycine as the sole nitrogen source.	Glycine	151-158	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	29-33
23613100-11	2013	Pharmacogenomic studies have shown that patients with polymorphisms of the beta2-adrenoreceptor (ADRB2; 16 Arg/Arg and 16 Arg/Gly) are particularly responsive to treatment with tiotropium.	Glycine	126-129	adrenoceptor beta 2	Homo sapiens	75-95
23613100-11	2013	Pharmacogenomic studies have shown that patients with polymorphisms of the beta2-adrenoreceptor (ADRB2; 16 Arg/Arg and 16 Arg/Gly) are particularly responsive to treatment with tiotropium.	Glycine	126-129	adrenoceptor beta 2	Homo sapiens	97-102
23613100-15	2013	Specifically, patients with high sputum neutrophil levels or with 16 Arg/Arg or 16 Arg/Gly polymorphism of the ADRB2 gene appear to respond best.	Glycine	87-90	adrenoceptor beta 2	Homo sapiens	111-116
23390665-3	2004	It shares an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2) with gastrin-releasing peptide (GRP), which is responsible for receptor binding and signal transduction (4, 5).	Glycine	55-58	gastrin releasing peptide	Homo sapiens	81-106
23390665-3	2004	It shares an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2) with gastrin-releasing peptide (GRP), which is responsible for receptor binding and signal transduction (4, 5).	Glycine	55-58	gastrin releasing peptide	Homo sapiens	108-111
23573143-4	2013	The expression level of phosphorylated FAK, Akt, ERK1/2, and Rb was decreased p21 expression while level was increased in WEHI-3 treated with GLY.	Glycine	142-145	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	78-81
23573143-6	2013	Moreover, experimental results demonstrated that GLY decreased the protein expression and enzyme activity of MMP-2 and MMP-9.	Glycine	49-52	matrix metallopeptidase 2	Mus musculus	109-114
8830251-2	1996	The Saccharomyces cerevisiae GCV2 gene, encoding the P-protein has been cloned by complementation of the gsd2 mutation which prevents cells converting glycine to serine or using glycine as the sole nitrogen source.	Glycine	151-158	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	105-109
23806011-2	2013	In the first case, a new delta-globin variant, Hb A2-Pierre-Benite [delta83(EF7)Gly Arg; HBD: c.250G&gt;C] is associated with Hb Groene Hart [alpha119(H2)Pro Ser (alpha1); HBA1: c.358C&gt;T], an alpha-thalassemic variant.	Glycine	80-83	FAM3 metabolism regulating signaling molecule D	Homo sapiens	76-79
23806011-2	2013	In the first case, a new delta-globin variant, Hb A2-Pierre-Benite [delta83(EF7)Gly Arg; HBD: c.250G&gt;C] is associated with Hb Groene Hart [alpha119(H2)Pro Ser (alpha1); HBA1: c.358C&gt;T], an alpha-thalassemic variant.	Glycine	80-83	HBD	Homo sapiens	89-92
8830251-2	1996	The Saccharomyces cerevisiae GCV2 gene, encoding the P-protein has been cloned by complementation of the gsd2 mutation which prevents cells converting glycine to serine or using glycine as the sole nitrogen source.	Glycine	178-185	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	29-33
23535599-6	2013	Mass spectrometry showed that IpaJ cleaved the peptide bond between N-myristoylated glycine-2 and asparagine-3 of human ARF1, thereby providing a new mechanism for host secretory inhibition by a bacterial pathogen.	Glycine	84-91	ADP ribosylation factor 1	Homo sapiens	120-124
8830251-4	1996	Expression of GCV2 was induced by the addition of more than 200 microM glycine in the medium, and a maximal sixfold induction occurred above 1 mM.	Glycine	71-78	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	14-18
8567671-2	1996	The aim of this paper is to study are involvement of glycine 142 in LPL secretion and to elucidate the intracellular destination of the altered protein that remains inside the cell.	Glycine	53-60	lipoprotein lipase	Homo sapiens	68-71
23964556-5	2013	CONCLUSIONS: Our study demonstrated that nocturnal asthma was associated with ADRB2 Arg/Gly polymorphisms but not with ADRB2 Gln/Glu polymorphisms.	Glycine	88-91	adrenoceptor beta 2	Homo sapiens	78-83
23430561-9	2013	PNPO gene sequencing identified a homozygous mutation in a highly conserved area in exon 3: c.352G&gt;A p.G118R, predicting substitution of arginine for glycine.	Glycine	153-160	pyridoxamine 5'-phosphate oxidase	Homo sapiens	0-4
23548524-4	2013	METHODS: We conducted a retrospective analysis of the effects of ADRB2 haplotypes at position 16 (Gly/Arg) and 27(Gln/Glu) in 449 patients with a physician diagnosis of asthma who were responsive to methacholine (ie, provocation concentration that caused a decrease in forced expiratory volume in 1 second [FEV(1)] of 20% [PC(20)], &lt;8 mg/mL).	Glycine	98-101	adrenoceptor beta 2	Homo sapiens	65-70
9075580-9	1996	The reactivity with one monoclonal antibody, H19, was abrogated by the mutations 61Tyr--&gt;Gly and 61Tyr--&gt;Ala.	Glycine	92-95	H19 imprinted maternally expressed transcript	Homo sapiens	45-48
22890624-2	2012	The ClpB monomer contains two nucleotide-binding domains (D1, D2), a coiled-coil domain, and an N-terminal domain attached to D1 with a 17-residue-long unstructured linker containing a Gly-Gly motif.	Glycine	185-188	caseinolytic mitochondrial matrix peptidase chaperone subunit B	Homo sapiens	4-8
22890624-2	2012	The ClpB monomer contains two nucleotide-binding domains (D1, D2), a coiled-coil domain, and an N-terminal domain attached to D1 with a 17-residue-long unstructured linker containing a Gly-Gly motif.	Glycine	189-192	caseinolytic mitochondrial matrix peptidase chaperone subunit B	Homo sapiens	4-8
23262140-3	2013	METHODS: AnxA5 and the control protein were recombinantly expressed with a C-terminal "Sel-tag", the tetrapeptide -Gly-Cys-Sec-Gly-COOH.	Glycine	115-118	annexin A5	Mus musculus	9-14
8626044-0	1996	Metabolism and influence of glycine-extended gastrin on gastric acid secretion in man.	Glycine	28-35	gastrin	Homo sapiens	45-52
23262140-3	2013	METHODS: AnxA5 and the control protein were recombinantly expressed with a C-terminal "Sel-tag", the tetrapeptide -Gly-Cys-Sec-Gly-COOH.	Glycine	127-130	annexin A5	Mus musculus	9-14
23181524-7	2013	The knockout mutant bou-2 showed the hallmarks of a photorespiratory growth phenotype, an elevated CO(2)  compensation point, and excessive accumulation of glycine.	Glycine	156-163	Mitochondrial substrate carrier family protein	Arabidopsis thaliana	20-23
23237781-12	2013	The finding that SNP variations in the human GLYAT gene influence the kinetic properties of the enzyme may explain some of the inter-individual variation in glycine conjugation capacity, which is relevant to the metabolism of xenobiotics such as aspirin and the industrial solvent xylene, and to the treatment of some metabolic disorders.	Glycine	157-164	glycine-N-acyltransferase	Homo sapiens	45-50
23300085-2	2013	Tal(2009) and Tal(901-1) can undergo proteolytic processing mid-protein at the glycine-rich sequence GG(S/N)SGGG, removing their C-terminal structural lysin.	Glycine	79-86	transaldolase 1	Homo sapiens	0-3
23300085-2	2013	Tal(2009) and Tal(901-1) can undergo proteolytic processing mid-protein at the glycine-rich sequence GG(S/N)SGGG, removing their C-terminal structural lysin.	Glycine	79-86	transaldolase 1	Homo sapiens	14-17
22972628-1	2013	BACKGROUND: The authors conducted a systematic review and meta-analysis to examine whether patients who had metastatic colorectal cancer (mCRC) with the v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) p.G13D mutation (an amino acid substitution at position 13 in KRAS from a glycine to an aspartic acid) and received cetuximab treatment had better clinical outcomes than patients who had mCRC tumors with KRAS codon 12 mutations.	Glycine	287-294	KRAS proto-oncogene, GTPase	Rattus norvegicus	207-211
22978602-0	2013	Oleoyl-L-carnitine inhibits glycine transport by GlyT2.	Glycine	28-35	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	49-54
22978602-1	2013	BACKGROUND AND PURPOSE: Concentrations of extracellular glycine in the CNS are regulated by two Na(+)/Cl(-) -dependent glycine transporters, GlyT1 and GlyT2.	Glycine	56-63	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	151-156
22978602-5	2013	KEY RESULTS: Oleoyl-L-carnitine inhibited glycine transport by GlyT2, with an IC(50) of 340 nM, which is 15-fold more potent than the previously identified lipid inhibitor N-arachidonyl-glycine.	Glycine	42-49	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	63-68
23717042-2	2013	Mutant Hsp cages (HspG41C) were expressed in Escherichia coli by substituting glycine 41 located inside the cage with a cysteine residue to allow conjugation with a fluorophore or a drug.	Glycine	78-85	heat shock protein 90 beta family member 2, pseudogene	Homo sapiens	7-10
22887640-6	2013	In osteoclasts actively resorbing bone, dynein-dynactin intimately co-localizes with the CAP-Gly domain-containing microtubule plus-end protein CLIP-170 at the resorptive front, thus orientating the ruffled border as a microtubule plus-end domain.	Glycine	93-96	CAP-Gly domain containing linker protein 1	Homo sapiens	144-152
23430553-3	2013	The enzymatic block results from a deficiency of sarcosine dehydrogenase (SarDH), a liver mitochondrial matrix enzyme that converts sarcosine into glycine.	Glycine	147-154	sarcosine dehydrogenase	Homo sapiens	74-79
23516639-8	2013	The rs7775 SNP in exon 6 of SFRP3 gene that codes for either arginine or glycine exhibited very strong association with breast cancer, even after Bonferroni"s correction.	Glycine	73-80	frizzled related protein	Homo sapiens	28-33
23217709-7	2012	Stx17 has a unique C-terminal hairpin structure mediated by two tandem transmembrane domains containing glycine zipper-like motifs, which is essential for its association with the autophagosomal membrane.	Glycine	104-111	syntaxin 17	Homo sapiens	0-5
22995908-6	2012	We identified residues 357-418 in the intracellular TM3-4 loop as being required for reconstitution of functional glycine-gated channels.	Glycine	114-121	tropomyosin 3	Homo sapiens	52-57
22825317-2	2012	Sarcosine is a key intermediate in 1-carbon metabolism and under normal circumstances is converted to glycine by the enzyme sarcosine dehydrogenase.	Glycine	102-109	sarcosine dehydrogenase	Homo sapiens	124-147
22825317-4	2012	Using the "candidate gene approach" we sequenced the gene encoding sarcosine dehydrogenase (SARDH), which plays an important role in the conversion of sarcosine to glycine, and found four different mutations (P287L, V71F, R723X, R514X) in three patients.	Glycine	164-171	sarcosine dehydrogenase	Homo sapiens	67-90
22825317-4	2012	Using the "candidate gene approach" we sequenced the gene encoding sarcosine dehydrogenase (SARDH), which plays an important role in the conversion of sarcosine to glycine, and found four different mutations (P287L, V71F, R723X, R514X) in three patients.	Glycine	164-171	sarcosine dehydrogenase	Homo sapiens	92-97
23115806-4	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
23039317-7	2012	Two conformers were observed for ZG3, with the majority of the population in a C11/C7/C7/pi(g-) structure that forms a full loop of the glycine chain.	Glycine	136-143	aldo-keto reductase family 1 member C4	Homo sapiens	79-82
22883364-7	2012	Children exposed to mildewy odor with ADRB2 Arg/Arg genotype were associated with being awakened at night due to wheezing (OR=1.95, 95% CI, 1.14-3.36), compared to those without exposure and with the ADRB2 Gly allele.	Glycine	206-209	adrenoceptor beta 2	Homo sapiens	38-43
22837388-1	2012	D-Amino acid oxidase (DAAO) catalyzes the oxidative deamination of D-amino acids including D-serine, a full agonist at the glycine modulatory site of the N-methyl-d-aspartate (NMDA) receptor.	Glycine	123-130	D-amino acid oxidase	Mus musculus	0-20
22837388-1	2012	D-Amino acid oxidase (DAAO) catalyzes the oxidative deamination of D-amino acids including D-serine, a full agonist at the glycine modulatory site of the N-methyl-d-aspartate (NMDA) receptor.	Glycine	123-130	D-amino acid oxidase	Mus musculus	22-26
22898812-5	2012	Mutating Ser-340/341 in the N-ATP7B individually or together to Ala, Gly, Thr, or Asp produced active protein and shifted the steady-state localization of ATP7B to vesicles, independently of copper levels.	Glycine	69-72	ATPase copper transporting beta	Homo sapiens	30-35
22287125-1	2012	The purpose of this study was to use a near-infrared (NIR) fluorescent cyclic His-Try-Gly-Phe peptide to characterize and image the expressions of matrix metalloproteinases (MMPs), which are correlated with cancer promotion, in an inflammation-induced colorectal cancer (ICRC) model.	Glycine	86-89	matrix metallopeptidase 2	Mus musculus	174-178
22767504-7	2012	Moreover, a peptide pADPr blot assay of G3BP revealed that pADPr binds to the glycine-arginine-rich domain of G3BP.	Glycine	78-85	G3BP stress granule assembly factor 1	Homo sapiens	40-44
22767504-7	2012	Moreover, a peptide pADPr blot assay of G3BP revealed that pADPr binds to the glycine-arginine-rich domain of G3BP.	Glycine	78-85	G3BP stress granule assembly factor 1	Homo sapiens	110-114
22854961-1	2012	Loss of synaptic inhibition by gamma-aminobutyric acid and glycine due to potassium chloride cotransporter-2 (KCC2) down-regulation in the spinal cord is a critical mechanism of synaptic plasticity in neuropathic pain.	Glycine	59-66	solute carrier family 12 member 5	Homo sapiens	110-114
22854961-5	2012	Inhibiting calpain blocks KCC2 cleavage induced by nerve injury and NMDA, thereby normalizing E(glycine).	Glycine	96-103	solute carrier family 12 member 5	Homo sapiens	26-30
22705714-7	2012	The high abundance of the H-protein of the glycine decarboxylase complex (Gcv3p) indicated the availability of glycine in the environment.	Glycine	43-50	glycine decarboxylase subunit H	Saccharomyces cerevisiae S288C	74-79
21955180-2	2012	Glycine availability is also crucial for regulating alcohol consumption and the glycine transporter 1 (GlyT-1) inhibitor Org25935 robustly decreases alcohol intake in rats.	Glycine	0-7	solute carrier family 6 member 9	Rattus norvegicus	103-109
22261077-1	2012	Non ketotic hyperglycinemia is a rare inborn error of glycine metabolism due to deficient activity of glycine cleavage system, a multienzymatic complex consisting of four protein subunits: the P-protein, the H-protein, the T-protein and the L-protein.	Glycine	17-24	myosin binding protein H	Homo sapiens	208-217
22722930-6	2012	Although the high transport rate of the Gly-545 truncation mutant was associated with higher levels of membrane expression (than full-length MATE1), suggesting the 13(th) TMH may influence substrate translocation, the selectivity profile of the mutant indicated that TMH13 has little impact on ligand binding.	Glycine	40-43	solute carrier family 47 member 1	Homo sapiens	141-146
22610100-0	2012	Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor.	Glycine	192-199	chromosome 20 open reading frame 181	Homo sapiens	87-115
22637580-2	2012	G146V actin filaments bind cofilin only minimally, presumably because cofilin binding requires the large and small actin domains to twist with respect to one another around the hinge region containing Gly-146, and the mutation inhibits that twisting motion.	Glycine	201-204	cofilin	Saccharomyces cerevisiae S288C	27-34
22637580-2	2012	G146V actin filaments bind cofilin only minimally, presumably because cofilin binding requires the large and small actin domains to twist with respect to one another around the hinge region containing Gly-146, and the mutation inhibits that twisting motion.	Glycine	201-204	cofilin	Saccharomyces cerevisiae S288C	70-77
22796215-4	2012	The protective effect of glycine was associated with reduction of terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) positive cells, deactivation of phosphor-JNK, inhibition of caspase-3 cleavage, down-regulation of FasL/Fas, and up-regulation of bcl-2 and bcl-2/bax in the mouse I/R penumbra.	Glycine	25-32	mitogen-activated protein kinase 8	Mus musculus	183-186
22796215-4	2012	The protective effect of glycine was associated with reduction of terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) positive cells, deactivation of phosphor-JNK, inhibition of caspase-3 cleavage, down-regulation of FasL/Fas, and up-regulation of bcl-2 and bcl-2/bax in the mouse I/R penumbra.	Glycine	25-32	caspase 3	Mus musculus	202-211
22796215-4	2012	The protective effect of glycine was associated with reduction of terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) positive cells, deactivation of phosphor-JNK, inhibition of caspase-3 cleavage, down-regulation of FasL/Fas, and up-regulation of bcl-2 and bcl-2/bax in the mouse I/R penumbra.	Glycine	25-32	BCL2-associated X protein	Mus musculus	288-291
8626044-2	1996	The effect on gastric acid secretion and the pharmacokinetics of glycine-extended gastrin-17 were studied in 8 normal subjects.	Glycine	65-72	gastrin	Homo sapiens	82-89
8626044-7	1996	The postprandial rise in amidated gastrin was unaffected by concomitant infusion of glycine-extended gastrin-17.	Glycine	84-91	gastrin	Homo sapiens	101-108
8626044-8	1996	A reduction in glycine-extended gastrin-17 concentrations in plasma during constant-rate infusion of the peptide was observed after a protein meal (p &lt; 0.05).	Glycine	15-22	gastrin	Homo sapiens	32-39
8626044-9	1996	This reduction was reflected by an increase in glycine-extended gastrin-17 is without immediate effect on gastric output in man.	Glycine	47-54	gastrin	Homo sapiens	64-71
9110930-3	1996	Pro and Ala at position 2 as well as Ile at position 9 were confirmed to be main anchor residues, while Gly at position 2 as well as Val, Leu, and Met at position 9 were weak anchor residues for HLA-B*5101.	Glycine	104-107	major histocompatibility complex, class I, B	Homo sapiens	195-200
22699852-4	2012	EgRBP42 consists of two N-terminal RNA recognition motifs and a glycine-rich domain at the C-terminus.	Glycine	64-71	UBP1-associated protein 2C	Elaeis guineensis	0-7
8951616-3	1996	One of the remarkable properties of DPPIV is that its activity is greatly enhanced by Gly-X (X: especially, Gly, Gln, Glu and Ser) dipeptides.	Glycine	86-89	dipeptidyl peptidase 4	Homo sapiens	36-41
23079818-4	2012	The missense mutation c.3235G&gt;A was identified within exon 45 of the COL1A1 gene in a 16-year-old girl diagnosed as having OI type I; it resulted in substitution of a glycine residue (G) by a serine (S) at codon 1079 (p.G1079S).	Glycine	170-177	collagen type I alpha 1 chain	Homo sapiens	72-78
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	0-7	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta	Mus musculus	101-113
22732655-9	2012	Glycine alone stimulated NF-kappaB activation in an unusual way such that the inhibitor kappaB-beta (IkappaB-beta) degradation was more significant than that of the inhibitor kappaB-alpha (IkappaB-alpha) and led to NF-kappaB complexes comprised of p50 and p65 subunits; IkappaB-epsilon degradation did not affect by glycine.	Glycine	316-323	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta	Mus musculus	101-113
9112225-3	1996	Among these, the hnRNP-A/B proteins form a subgroup of highly related proteins consisting of two adjacent RNA binding domains (RBD) within the N-terminal parts, whereas the C-terminal halves contain almost 50% glycine residues.	Glycine	210-217	heterogeneous nuclear ribonucleoprotein A/B	Homo sapiens	17-26
22682753-8	2012	A KRAS codon 12 mutation, the GGT   GTT transversion, corresponding to the Gly   Val amino acid change was identified in the absence of other genetic alterations commonly found in PTC.	Glycine	75-78	KRAS proto-oncogene, GTPase	Homo sapiens	2-6
8786846-2	1995	Addition of large saturating concentrations of glycine (100 microM and 1 mM) to the superfusate resulted in increased extracellularly recorded NMDA receptor-mediated components of excitatory postsynaptic potentials (EPSPs) recorded in area CA1.	Glycine	47-54	carbonic anhydrase 1	Rattus norvegicus	240-243
7487919-10	1995	This lack of a MASP-rMBPD association corresponds to a failure of the Gly-54--&gt;Asp form of MBP to activate complement.	Glycine	70-73	MBL associated serine protease 1	Homo sapiens	15-19
22581580-1	2012	Fibrodysplasia ossificans progressiva (FOP) causes extensive heterotopic bone formation due to heterozygous mutations in the glycine-serine activation domain of ACVR1 (ALK2), a bone morphogenetic protein type I receptor.	Glycine	125-132	activin A receptor type 1	Homo sapiens	161-166
7487919-11	1995	Our results provide a biochemical basis for the functional deficit in the Gly-54--&gt;Asp allelic form of MBP and suggest that the proMASP/MASP binding site maps to the fifth collagen repeat of MBP.	Glycine	74-77	MBL associated serine protease 1	Homo sapiens	134-138
22581580-1	2012	Fibrodysplasia ossificans progressiva (FOP) causes extensive heterotopic bone formation due to heterozygous mutations in the glycine-serine activation domain of ACVR1 (ALK2), a bone morphogenetic protein type I receptor.	Glycine	125-132	activin A receptor type 1	Homo sapiens	168-172
7474152-4	1995	Within the N-terminal 23 residues of VP2, two subsites able to induce neutralizing antibodies and which overlapped by only two glycine residues at positions 10 and 11 could be discriminated.	Glycine	127-134	VP2	Canine parvovirus	37-40
22593943-6	2004	However, rapid sequestration into the nerve terminals and surrounding glial cells by two high-affinity transporters, designated as GlyT-1 and GlyT-2, block the activity of glycine on the NMDAR in the synapse (4).	Glycine	172-179	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	142-148
22416082-3	2012	Central h(Gly(2))GLP-2 administration significantly suppressed food and water intake with acute weight loss at 2 h. Further, central h(Gly(2))GLP-2 robustly induced c-Fos activation in the hypothalamic arcuate, dorsomedial, ventromedial, paraventricular, and the lateral hypothalamic nuclei.	Glycine	10-13	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	165-170
22416082-3	2012	Central h(Gly(2))GLP-2 administration significantly suppressed food and water intake with acute weight loss at 2 h. Further, central h(Gly(2))GLP-2 robustly induced c-Fos activation in the hypothalamic arcuate, dorsomedial, ventromedial, paraventricular, and the lateral hypothalamic nuclei.	Glycine	135-138	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	165-170
22416082-6	2012	Treatment with h(Gly(2))GLP-2 stimulated c-Fos expression and phosphorylation of cAMP response element-binding protein/activating transcription factor-1.	Glycine	17-20	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	41-46
7559487-5	1995	Replacing all three of these sites with glycine decreased phosphorylation by &gt; 90% and reduced pleckstrin"s ability to inhibit phosphoinositide hydrolysis by as much as 80%.	Glycine	40-47	pleckstrin	Homo sapiens	98-108
22455451-3	2012	It is well-documented that the RGD (Arg-Gly-Asp) motif exhibits high binding affinity to integrin alpha(v)beta(3), which is abundantly expressed in cancer cells and specifically associated with angiogenesis on tumors.	Glycine	40-43	integrin subunit alpha V	Homo sapiens	89-113
7557090-4	1995	METHODS: Site-directed mutagenesis of a full-length rat LPH complementary DNA was used to convert the rat homologues E1274 and E1750 to aspartic acid or glycine.	Glycine	153-160	lactase	Rattus norvegicus	56-59
22536614-6	2004	However, rapid sequestration into the nerve terminals and surrounding glial cells by two high-affinity transporters, designated as GlyT-1 and GlyT-2, block the activity of glycine on the NMDAR in the synapse (3).	Glycine	172-179	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	142-148
22414695-1	2012	The activity of the neuron-specific K(+), Cl(-) co-transporter 2 (KCC2) is required for hyperpolarizing action of GABA and glycine.	Glycine	123-130	solute carrier family 12 member 5	Homo sapiens	66-70
7476899-6	1995	Glycine reversal of ethanol inhibition suggested that ethanol might lower the affinity of glycine for the NMDA receptor and thereby decrease response magnitude.	Glycine	90-97	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	106-119
7476899-7	1995	Consistent with this hypothesis, ethanol significantly reduced glycine affinity at NR1/NR2A and NR1/NR2C receptors.	Glycine	63-70	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	83-86
7476899-7	1995	Consistent with this hypothesis, ethanol significantly reduced glycine affinity at NR1/NR2A and NR1/NR2C receptors.	Glycine	63-70	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	96-99
7476899-7	1995	Consistent with this hypothesis, ethanol significantly reduced glycine affinity at NR1/NR2A and NR1/NR2C receptors.	Glycine	63-70	glutamate receptor, ionotropic, N-methyl D-aspartate 2C L homeolog	Xenopus laevis	100-104
7476899-9	1995	Activation of the NR1/NR2D heteromers by NMDA and low concentrations of glycine elicited responses characterized by an initial peak followed by a lower-amplitude plateau response, which is consistent with glycine-sensitive desensitization as previously described for native NMDA receptors.	Glycine	72-79	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	18-21
22330678-10	2012	We further demonstrate that the interaction of cathepsin Z with arginine-glycine-aspartic acid-binding integrins, specifically alphavbeta5, mediates the changes seen in adhesion of PDAC cells.	Glycine	73-80	cathepsin Z	Homo sapiens	47-58
7476899-9	1995	Activation of the NR1/NR2D heteromers by NMDA and low concentrations of glycine elicited responses characterized by an initial peak followed by a lower-amplitude plateau response, which is consistent with glycine-sensitive desensitization as previously described for native NMDA receptors.	Glycine	205-212	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	18-21
7476899-10	1995	In addition, nondesensitizing NR1/NR2B responses elicited in the presence of subsaturating concentrations of glycine were frequently converted into desensitizing responses by the addition of ethanol, an effect that was reversed with increasing glycine concentrations.	Glycine	109-116	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	30-33
7476899-10	1995	In addition, nondesensitizing NR1/NR2B responses elicited in the presence of subsaturating concentrations of glycine were frequently converted into desensitizing responses by the addition of ethanol, an effect that was reversed with increasing glycine concentrations.	Glycine	109-116	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	34-38
7476899-10	1995	In addition, nondesensitizing NR1/NR2B responses elicited in the presence of subsaturating concentrations of glycine were frequently converted into desensitizing responses by the addition of ethanol, an effect that was reversed with increasing glycine concentrations.	Glycine	244-251	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	30-33
7476899-10	1995	In addition, nondesensitizing NR1/NR2B responses elicited in the presence of subsaturating concentrations of glycine were frequently converted into desensitizing responses by the addition of ethanol, an effect that was reversed with increasing glycine concentrations.	Glycine	244-251	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	34-38
21947881-2	2012	A Gly to Ser change RAGE gene was analyzed by PCR-RFLP techniques.	Glycine	2-5	long intergenic non-protein coding RNA 914	Homo sapiens	20-24
7476899-11	1995	The ability of ethanol to promote glycine-sensitive desensitization further suggests an interaction between glycine and ethanol inhibition of the NMDA receptor.	Glycine	34-41	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	146-159
7476899-11	1995	The ability of ethanol to promote glycine-sensitive desensitization further suggests an interaction between glycine and ethanol inhibition of the NMDA receptor.	Glycine	108-115	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	146-159
8562067-7	1995	Amino acid analysis, Edman degradation, and FAB-MS identified T11 as the N-blocked decapeptide pyro-Gln-Pro-Val-Trp-Gln-Asp-Glu-Gly-Gln-Arg derived from the N-terminus of pZPC.	Glycine	128-131	CD2 molecule	Homo sapiens	62-65
22275517-1	2012	Loading of GABA and glycine into synaptic vesicles via the vesicular GABA transporter (VGAT) is an essential step in inhibitory neurotransmission.	Glycine	20-27	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	59-85
22275517-1	2012	Loading of GABA and glycine into synaptic vesicles via the vesicular GABA transporter (VGAT) is an essential step in inhibitory neurotransmission.	Glycine	20-27	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	87-91
7501234-1	1995	We studied the mechanism by which thyrotropin-releasing hormone (TRH)-Gly stimulated prolactin and thyrotropin (TSH) secretion in pituitary, using a pituitary mammotropic cell line, GH3 cells, and a cell line stably expressing a human TRH receptor (TRH-R).	Glycine	70-73	thyrotropin releasing hormone receptor	Homo sapiens	235-247
7501234-1	1995	We studied the mechanism by which thyrotropin-releasing hormone (TRH)-Gly stimulated prolactin and thyrotropin (TSH) secretion in pituitary, using a pituitary mammotropic cell line, GH3 cells, and a cell line stably expressing a human TRH receptor (TRH-R).	Glycine	70-73	thyrotropin releasing hormone receptor	Homo sapiens	249-254
7636245-6	1995	Different from these receptors, CD97 has an extended extracellular region of 433 amino acids that possesses three N-terminal epidermal growth factor-like domains, two of them with a calcium-binding site, and a single Arg-Gly-Asp (RGD) motif.	Glycine	221-224	adhesion G protein-coupled receptor E5	Homo sapiens	32-36
22434630-2	2012	These probes were based on the PLG*LWAR peptide sequence, known to be hydrolyzed between Gly and Leu by a broad panel of MMPs.	Glycine	89-92	matrix metallopeptidase 2	Mus musculus	121-125
8543567-2	1995	The amino acid sequence of its NH2-terminus was determined to be Val-Pro-Asn-Ser-Leu-Asp-Trp-Arg-Glu-Lys-Gly-Tyr-Val-Thr-Pro-, which differed from that of rat cathepsin L and was not found in the amino acid sequence data bank.	Glycine	105-108	cathepsin L	Rattus norvegicus	159-170
22169029-0	2012	Comparative 4f-4f absorption spectral study for the interactions of Nd(III) with some amino acids: Preliminary thermodynamics and kinetic studies of interaction of Nd(III):glycine with Ca(II).	Glycine	172-179	carbonic anhydrase 2	Homo sapiens	185-191
22169029-6	2012	Kinetic studies for the complexation of Nd(III):glycine:Ca(II) have also been discussed at different temperatures in DMF medium and from it the values of activation energy (E(a)) and thermodynamic parameters like DeltaH , DeltaS  and DeltaG  for the complexation are evaluated.	Glycine	48-55	carbonic anhydrase 2	Homo sapiens	56-62
7629520-4	1995	The complementary DNA sequence of the alternatively spliced form of icIL-1ra shows that the predicted protein differs from classical icIL-1ra in the NH2 terminus by insertion of a leaderless sequence of 21 amino acids rich in glycine and glutamic acid residues.	Glycine	226-233	interleukin 1 receptor antagonist	Homo sapiens	68-76
22178676-8	2012	However, numbers of c-Fos-LI neurons in the glycine and strychnine groups were both significantly less than that in the saline group.	Glycine	44-51	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	20-25
7576611-5	1995	A 75 kD recombinant protein, ProNectin F, containing 13 copies of the cell recognition epitope of fibronectin, Val-Thr-Gly-Arg-Gly-Asp-Ser-Pro-Ala-Ser, vigorously supported blastocyst outgrowth.	Glycine	119-122	fibronectin 1	Mus musculus	98-109
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	5-12	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	Mus musculus	86-90
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	136-143	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	Mus musculus	43-47
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	136-143	axin 1	Mus musculus	48-52
22307604-8	2012	The bivalent binding of Axin to TNKS is required for Axin turnover, since mutations in either gate-binding glycine residue in Axin lead to Axin stabilization in the cell.	Glycine	107-114	axin 1	Mus musculus	24-28
22307604-8	2012	The bivalent binding of Axin to TNKS is required for Axin turnover, since mutations in either gate-binding glycine residue in Axin lead to Axin stabilization in the cell.	Glycine	107-114	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	Mus musculus	32-36
22307604-8	2012	The bivalent binding of Axin to TNKS is required for Axin turnover, since mutations in either gate-binding glycine residue in Axin lead to Axin stabilization in the cell.	Glycine	107-114	axin 1	Mus musculus	53-57
22307604-8	2012	The bivalent binding of Axin to TNKS is required for Axin turnover, since mutations in either gate-binding glycine residue in Axin lead to Axin stabilization in the cell.	Glycine	107-114	axin 1	Mus musculus	53-57
22307604-8	2012	The bivalent binding of Axin to TNKS is required for Axin turnover, since mutations in either gate-binding glycine residue in Axin lead to Axin stabilization in the cell.	Glycine	107-114	axin 1	Mus musculus	53-57
7790891-6	1995	In vivo microdialysis of rodent brain revealed that the extracellular concentration of free D-Ser in the frontal cortex (6.5 microM) was high enough to saturate the Gly site on the NMDA receptor, but that in the cerebellum was not.	Glycine	165-168	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	181-194
22366005-1	2012	OBJECTIVE: To obtain a specific antagonist of CXCR4, SDF-1P2G54 by mutating SDF-1 second proline (P) into glycin (G) and removing the alpha-helix of its C-terminal.	Glycine	106-112	C-X-C motif chemokine receptor 4	Homo sapiens	46-51
7477728-4	1995	A single mutation was found in the OMGP gene which resulted in an amino-acid change of glycine to aspartic acid.	Glycine	87-94	oligodendrocyte myelin glycoprotein	Homo sapiens	35-39
21954455-1	2011	Several studies in humans or transgenic animals have reported that the 389 Arg or Gly polymorphic variation of the beta1-adrenergic receptor (AR) is associated with differential responses to beta-blocker therapy and/or myocardial disease progression.	Glycine	82-85	adrenergic receptor, beta 1	Mus musculus	115-140
21954455-1	2011	Several studies in humans or transgenic animals have reported that the 389 Arg or Gly polymorphic variation of the beta1-adrenergic receptor (AR) is associated with differential responses to beta-blocker therapy and/or myocardial disease progression.	Glycine	82-85	adrenergic receptor, beta 1	Mus musculus	142-144
21889971-6	2011	The increase in the total number of C-fos activated Gly/GABA neurons was present primarily in the superficial dorsal horn (laminae I and II; control: 9%; CFA 4 days: 56%; SNI 2 weeks: 42%).	Glycine	52-55	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	36-41
21889971-7	2011	This increase in C-fos activation of Gly/GABA neurons occurred without significant changes in the total number of C-fos activated neurons, and without any significant changes in the mechanical thresholds in the hind paws after capsaicin injection.	Glycine	37-40	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	17-22
21889971-8	2011	The results showed that one-sided chronic pain, especially inflammation, significantly increases the C-fos activation pattern of spinal Gly/GABA neurons on the other side of the spinal cord.	Glycine	136-139	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	101-106
22091477-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
22459664-2	2012	METHODS: Two BN-derivatives of the general structure [M-chelator]-(spacer)-BN(2-14)-NH(2), where M: (99m)Tc or (185/187)Re, chelator: Gly-Gly-Cys-, spacer: -(arginine)(3)-, M-BN-A; spacer: -(ornithine)(3)-, M-BN-O; have been prepared and evaluated as tumor imaging agents.	Glycine	134-137	gastrin releasing peptide	Homo sapiens	13-15
22628564-2	2012	We investigated the importance of c/c-subunit contacts by site-directed mutagenesis of a conserved stretch of glycines (GxGxGxGxG) in a bacterial c(11) ring.	Glycine	110-118	RNA polymerase III subunit K	Homo sapiens	146-151
8581357-9	1995	Two new mutations were identified in exon 5 of the HexA gene: a C496 to G transversion, which produced an Arg166 --&gt;Gly alteration and a deletion of C498 which generated a shift in the reading frame.	Glycine	119-122	hexosaminidase subunit alpha	Homo sapiens	51-55
22322672-3	2012	Detailed characterization of Mamu-B*039:01, a common allele expressed in Chinese rhesus macaques, revealed a unique MHC:peptide-binding preference consisting of glycine at the second position.	Glycine	161-168	uncharacterized protein LOC700391	Macaca mulatta	29-35
22322672-4	2012	Peptides containing a glycine at the second position were shown to be antigenic from animals positive for Mamu-B*039:01.	Glycine	22-29	uncharacterized protein LOC700391	Macaca mulatta	106-112
22496447-1	2012	The human alpha-defensins (HNP) are synthesized in vivo as inactive prodefensins, and contain a conserved glycine, Gly(17), which is part of a beta-bulge structure.	Glycine	106-113	kallikrein related peptidase 8	Homo sapiens	27-30
22496447-1	2012	The human alpha-defensins (HNP) are synthesized in vivo as inactive prodefensins, and contain a conserved glycine, Gly(17), which is part of a beta-bulge structure.	Glycine	115-118	kallikrein related peptidase 8	Homo sapiens	27-30
21373768-9	2012	Glycine treatment suppressed these apoptotic events, signifying its protective role in Hg-induced hepatocyte apoptosis as referred by reduction of p38, JNK and ERK MAPK signaling pathways.	Glycine	0-7	mitogen-activated protein kinase 8	Mus musculus	152-155
22362770-6	2012	Alanine substitutions at positions Pro-113 Thr-115, Gly-117, Glu-122, and also Gln-109 enhanced the EphA2 receptor down-regulation and decreased p-ERK and p-AKT.	Glycine	52-55	EPH receptor A2	Homo sapiens	100-105
21880725-5	2011	We found that Ala-to-Gly exchange in human 15-LOX2 and human platelet 12-LOX induced major alterations in the reaction specificity with an increase of specific R-oxygenation products.	Glycine	21-24	lysyl oxidase	Homo sapiens	46-49
21640146-2	2011	The tumor vasculature-specific ligand asparagine-glycine-arginine (NGR) peptide targets the isoform of aminopeptidase N (APN, also referred to as CD13) that is expressed on the endothelial cells in angiogenic vessels such as the neovasculature in tumors.	Glycine	49-56	reticulon 4 receptor	Homo sapiens	67-70
7706471-5	1995	In site-directed mutagenesis/recombinant expression studies we have found that glycine at position 16 (Gly16) imparts an accelerated agonist-promoted downregulation of beta 2AR as compared to arginine at this position (Arg16).	Glycine	79-86	adenosine A2a receptor	Homo sapiens	168-176
7880841-0	1995	Mutagenesis of the H-ras p21 at glycine-60 residue disrupts GTP-induced conformational change.	Glycine	32-39	HRas proto-oncogene, GTPase	Homo sapiens	19-24
21824479-4	2011	We present here the structures of MPPED2 and two mutants, which show that the poor activity of MPPED2 is not only a consequence of the substitution of an active-site histidine residue by glycine but also due to binding of AMP or GMP to the active site.	Glycine	187-194	metallophosphoesterase domain containing 2	Homo sapiens	34-40
21824479-4	2011	We present here the structures of MPPED2 and two mutants, which show that the poor activity of MPPED2 is not only a consequence of the substitution of an active-site histidine residue by glycine but also due to binding of AMP or GMP to the active site.	Glycine	187-194	metallophosphoesterase domain containing 2	Homo sapiens	95-101
20641531-7	2004	A tripeptide sequence consisting of Arg-Gly-Asp (RGD) is identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including alphavbeta3.	Glycine	40-43	vitronectin	Homo sapiens	130-141
22475485-3	2012	GLYAT catalyzes glycine-N-acyltransfer reaction with benzoyl-CoA acting as a typical aralkyl transferase, while GLYATL1 catalyzed glutamine-N-acyltransfer reaction with phenylacetyl-CoA as an arylacetyl transferase.	Glycine	16-23	glycine-N-acyltransferase	Homo sapiens	0-5
22768954-1	2012	The intrinsic polymer properties of glycine-rich sequences are evaluated with a set of iso-1-cytochrome c variants with N-terminal inserts of the sequence (GGGGGK)(n) for n = 1-5.	Glycine	36-43	eukaryotic translation initiation factor 1	Homo sapiens	87-92
7880841-0	1995	Mutagenesis of the H-ras p21 at glycine-60 residue disrupts GTP-induced conformational change.	Glycine	32-39	H3 histone pseudogene 16	Homo sapiens	25-28
22275517-9	2012	Genotype differences in glycinergic mIPSCs were more evident during sustained stimulation by solutions with high potassium levels, suggesting that the estimated size of the readily releasable pool of glycine-containing vesicles was reduced in VGAT(+/-) mice.	Glycine	24-31	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	243-247
7880841-1	1995	The function of Gly-60, the conserved glycine in the DXXG domain of v-H-ras, was examined by site-directed mutagenesis.	Glycine	16-19	HRas proto-oncogene, GTPase	Homo sapiens	70-75
22457888-4	2004	Because the integrin alphavbeta3 binds with extracellular matrix proteins (e.g., vitronectin, fibronectin) through the exposed Arg-Gly-Asp tripeptide sequence, RGD-containing peptides have been intensively studied in the past decade as a vector for imaging alphavbeta3 expression (3, 4).	Glycine	131-134	integrin subunit alpha V	Homo sapiens	12-32
7880841-1	1995	The function of Gly-60, the conserved glycine in the DXXG domain of v-H-ras, was examined by site-directed mutagenesis.	Glycine	38-45	HRas proto-oncogene, GTPase	Homo sapiens	70-75
22457890-4	2004	Because the integrin alphavbeta3 binds with extracellular matrix proteins (e.g., vitronectin, fibronectin) through the exposed Arg-Gly-Asp tripeptide sequence, RGD-containing peptides have been intensively studied in the past decade as a vector for imaging alphavbeta3 expression (3, 4).	Glycine	131-134	integrin subunit alpha V	Homo sapiens	12-32
22234469-5	2012	Activity-based screens of the resultant mutants indicated that a single mature domain residue (Gly(391)) confers latency to hGDF9.	Glycine	95-98	growth differentiation factor 9	Homo sapiens	124-129
22234469-6	2012	Gly(391) forms part of the type I receptor binding site on hGDF9, and this residue is present in all species except mouse, rat, hamster, galago, and possum, in which it is substituted with an arginine.	Glycine	0-3	growth differentiation factor 9	Homo sapiens	59-64
21695312-0	2011	Highly diastereo- and enantioselective synthesis of syn-beta-substituted tryptophans via asymmetric Michael addition of a chiral equivalent of nucleophilic glycine and sulfonylindoles.	Glycine	156-163	synemin	Homo sapiens	39-42
21695312-1	2011	The asymmetric synthesis of syn-beta-substituted tryptophan derivatives was carried out by the Michael addition of chiral equivalent of nucleophilic glycine with sulfonylindoles, and high diastereo- and enantioselectivities were achieved.	Glycine	149-156	synemin	Homo sapiens	15-18
7876225-3	1995	Our studies on a family with Schmid metaphyseal chondrodysplasia demonstrated that the affected individuals were heterozygous for a single base substitution in the COL10A1 gene, which changed the codon GGC for glycine 618 to GTC for valine in the highly conserved region of the carboxyl-terminal NC1 domain and altered the amino acid sequence in the putative oligosaccharide attachment site.	Glycine	210-217	collagen type X alpha 1 chain	Homo sapiens	164-171
21529934-1	2011	Platelet adhesion to adsorbed plasma proteins, such as fibrinogen (Fg), has been conventionally thought to be mediated by the GPIIb/IIIa receptor binding to Arg-Gly-Asp (RGD)-like motifs in the adsorbed protein.	Glycine	161-164	integrin subunit alpha 2b	Homo sapiens	126-131
22359779-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
22359781-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
22307604-6	2012	Our crystal structure shows that in each TNKS-binding segment of Axin there is a conserved glycine residue that lies in the bottom of a narrow "gate" formed by two parallel tyrosine side chains on the TNKS surface.	Glycine	91-98	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	Mus musculus	41-45
22307604-6	2012	Our crystal structure shows that in each TNKS-binding segment of Axin there is a conserved glycine residue that lies in the bottom of a narrow "gate" formed by two parallel tyrosine side chains on the TNKS surface.	Glycine	91-98	axin 1	Mus musculus	65-69
22307604-6	2012	Our crystal structure shows that in each TNKS-binding segment of Axin there is a conserved glycine residue that lies in the bottom of a narrow "gate" formed by two parallel tyrosine side chains on the TNKS surface.	Glycine	91-98	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	Mus musculus	201-205
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	5-12	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	Mus musculus	43-47
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	5-12	axin 1	Mus musculus	48-52
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	5-12	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	Mus musculus	86-90
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	5-12	axin 1	Mus musculus	163-167
22307604-7	2012	This glycine-selection gate is crucial for TNKS-Axin interactions, as mutation of the TNKS gate-forming residues, or mutation of either glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Axin segment to TNKS.	Glycine	5-12	axin 1	Mus musculus	163-167
21633362-1	2011	Microarray-based comparative genomic hybridization analysis identified a 737-kb microdeletion of Xq11.1, including the cell division cycle 42 guanine nucleotide exchange factor (GEF)-9 gene (ARHGEF9), encoding collybistin, which has a pivotal role in formation of postsynaptic glycine and gamma-aminobutyric acid receptor clusters, in a male patient with severe mental retardation and epilepsy.	Glycine	277-284	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	142-176
21633362-1	2011	Microarray-based comparative genomic hybridization analysis identified a 737-kb microdeletion of Xq11.1, including the cell division cycle 42 guanine nucleotide exchange factor (GEF)-9 gene (ARHGEF9), encoding collybistin, which has a pivotal role in formation of postsynaptic glycine and gamma-aminobutyric acid receptor clusters, in a male patient with severe mental retardation and epilepsy.	Glycine	277-284	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	178-181
21633362-1	2011	Microarray-based comparative genomic hybridization analysis identified a 737-kb microdeletion of Xq11.1, including the cell division cycle 42 guanine nucleotide exchange factor (GEF)-9 gene (ARHGEF9), encoding collybistin, which has a pivotal role in formation of postsynaptic glycine and gamma-aminobutyric acid receptor clusters, in a male patient with severe mental retardation and epilepsy.	Glycine	277-284	Cdc42 guanine nucleotide exchange factor 9	Homo sapiens	191-198
7630488-2	1995	In oocytes expressing the NR1/2A subunits, ethanol (25, 50 and 100 mM) inhibited NMDA (100 microM)/glycine (10 microM) induced currents by 21, 31 and 47%; respectively.	Glycine	99-106	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	26-32
20641959-20	2004	A tripeptide sequence consisting of Arg-Gly-Asp (RGD) is identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including alphavbeta3.	Glycine	40-43	vitronectin	Homo sapiens	130-141
20850942-6	2011	Mutation analysis of the MTHFR gene revealed homozygous, tandem missense mutations c.[446G&gt;T; 447C&gt;T] in exon 3 of the MTHFR gene converting glycine to valine (Gly149Val).	Glycine	147-154	methylenetetrahydrofolate reductase	Homo sapiens	25-30
7630488-6	1995	In the absence of ethanol, glycine enhanced NMDA-induced currents with an EC50 of 1.42 microM for the NR1/NR2A combination and 0.51 microM for the NR1/NR2C combination.	Glycine	27-34	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	102-105
20850942-6	2011	Mutation analysis of the MTHFR gene revealed homozygous, tandem missense mutations c.[446G&gt;T; 447C&gt;T] in exon 3 of the MTHFR gene converting glycine to valine (Gly149Val).	Glycine	147-154	methylenetetrahydrofolate reductase	Homo sapiens	125-130
22133759-6	2012	METHODS: The effects of lidocaine and its metabolites monoethylglycinexylidide (MEGX), glycinexylidide, and N-ethylglycine on GlyT1 function were investigated in uptake experiments with [14C]-labeled glycine in primary rat astrocytes.	Glycine	63-70	solute carrier family 6 member 9	Rattus norvegicus	126-131
7630488-6	1995	In the absence of ethanol, glycine enhanced NMDA-induced currents with an EC50 of 1.42 microM for the NR1/NR2A combination and 0.51 microM for the NR1/NR2C combination.	Glycine	27-34	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	147-150
7630488-6	1995	In the absence of ethanol, glycine enhanced NMDA-induced currents with an EC50 of 1.42 microM for the NR1/NR2A combination and 0.51 microM for the NR1/NR2C combination.	Glycine	27-34	glutamate receptor, ionotropic, N-methyl D-aspartate 2C L homeolog	Xenopus laevis	151-155
21792844-1	2012	An 18-residue sequence Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Gly-Pro-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe (UK18) was designed to examine the effect of introducing a Gly-Pro segment into the middle of a potentially helical peptide.	Glycine	59-62	ANIB1	Homo sapiens	27-30
21792844-1	2012	An 18-residue sequence Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Gly-Pro-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe (UK18) was designed to examine the effect of introducing a Gly-Pro segment into the middle of a potentially helical peptide.	Glycine	59-62	ANIB1	Homo sapiens	43-46
7848273-10	1995	Rat MIP26 cDNA contains an -Asn-Gly- sequence at the C-terminus, which has been shown in other proteins to be particularly susceptible to spontaneous deamidation [Takemoto and Emmons (1991) Curr.	Glycine	32-35	major intrinsic protein of lens fiber	Rattus norvegicus	4-9
21792844-1	2012	An 18-residue sequence Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Gly-Pro-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe (UK18) was designed to examine the effect of introducing a Gly-Pro segment into the middle of a potentially helical peptide.	Glycine	59-62	ANIB1	Homo sapiens	43-46
21792844-1	2012	An 18-residue sequence Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Gly-Pro-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe (UK18) was designed to examine the effect of introducing a Gly-Pro segment into the middle of a potentially helical peptide.	Glycine	59-62	ANIB1	Homo sapiens	43-46
22175728-0	2012	Partial blocking of mouse DSPP processing by substitution of Gly(451)-Asp(452) bond suggests the presence of secondary cleavage site(s).	Glycine	61-64	dentin sialophosphoprotein	Mus musculus	26-30
22175728-2	2012	In the proteolytic processing of mouse DSPP, the peptide bond at Gly(451)-Asp(452) has been shown to be cleaved by bone morphogenetic protein 1 (BMP1)/Tolloid-like metalloproteinases.	Glycine	65-68	dentin sialophosphoprotein	Mus musculus	39-43
22175728-9	2012	Taken together, we concluded that in addition to the peptide bond Gly(451)-Asp(452), there must be a cryptic cleavage site or sites close to Asp(452) in the mouse DSPP that can be cleaved by BMP1.	Glycine	66-69	dentin sialophosphoprotein	Mus musculus	163-167
21448560-2	2011	Although paradigms have emerged for genotype/phenotype correlation in DEB, some pathogenic mutations in COL7A1, notably glycine substitutions within the type VII collagen triple helix, may lead to diagnostic difficulties, since certain glycine substitutions can result in either dominant or recessive mutant alleles.	Glycine	120-127	collagen type VII alpha 1 chain	Homo sapiens	104-110
21448560-2	2011	Although paradigms have emerged for genotype/phenotype correlation in DEB, some pathogenic mutations in COL7A1, notably glycine substitutions within the type VII collagen triple helix, may lead to diagnostic difficulties, since certain glycine substitutions can result in either dominant or recessive mutant alleles.	Glycine	236-243	collagen type VII alpha 1 chain	Homo sapiens	104-110
21448560-6	2011	In screening the COL7A1 gene for mutations in individuals with DEB our data highlight that delineation of glycine substitutions in type VII collagen has important implications for genetic counselling.	Glycine	106-113	collagen type VII alpha 1 chain	Homo sapiens	17-23
7833466-4	1995	The glycine at this position in antigen Fya exchanges with aspartic acid in antigen Fyb.	Glycine	4-11	FYN binding protein 1	Homo sapiens	84-87
21667357-6	2012	Among the 56 causative COL1A1 and COL1A2 mutations, 24 novel mutations were found, and 25 (44.6%) resulted in the substitution of a glycine within the Gly-X-Y triplet domain of the triple helix.	Glycine	132-139	collagen type I alpha 1 chain	Homo sapiens	23-29
7756179-7	1995	To mimic the temperature-sensitive mutant of yeast nuc2, an H-NUC mutant was made in which the highly conserved glycine 640 residue was changed to aspartic acid.	Glycine	112-119	cell division cycle 27	Homo sapiens	60-65
21667357-7	2012	Compared with COL1A1 haploinsufficiency (n = 23), patients with mutations affecting glycine residues had a severe skeletal phenotype.	Glycine	84-91	collagen type I alpha 1 chain	Homo sapiens	14-20
22119847-7	2012	Here we analyzed the interactions between CLIP-170 and p150(glued) CAP-Gly domains with the three EB homodimers and the EB1-EB3 heterodimer.	Glycine	71-74	microtubule associated protein RP/EB family member 1	Homo sapiens	120-127
22119847-10	2012	We succeeded to solve the crystal structure of a complex composed of a heterodimer of EB1 and EB3 C-termini together with the CAP-Gly domain of p150(glued).	Glycine	130-133	microtubule associated protein RP/EB family member 1	Homo sapiens	86-89
20422421-5	2011	ICAM-1 codon 241 polymorphism analysis was performed by two independent PCR reactions, based on the two set of oligoprimers specific for Arg (AGG) or Gly (GGG) coding sequence, respectively.	Glycine	150-153	intercellular adhesion molecule 1	Homo sapiens	0-6
7825568-5	1995	A G-to-A transition at codon 209-in exon 8 of the PFK-M gene, changing an encoded Gly to Asp, is responsible for the disease in a homozygous French Canadian patient.	Glycine	82-85	phosphofructokinase, muscle	Homo sapiens	50-55
21572694-1	2011	BACKGROUND AND OBJECTIVES: Two polymorphisms of beta(2)-adrenergic receptor (beta(2)-AR) gene, namely the substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic (Glu) at codon 27, are linked with functional changes in the beta(2)-AR in the respiratory system even though they are not deemed to be susceptibility genes for asthma per se.	Glycine	142-149	adrenoceptor beta 2	Homo sapiens	48-75
21572694-1	2011	BACKGROUND AND OBJECTIVES: Two polymorphisms of beta(2)-adrenergic receptor (beta(2)-AR) gene, namely the substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic (Glu) at codon 27, are linked with functional changes in the beta(2)-AR in the respiratory system even though they are not deemed to be susceptibility genes for asthma per se.	Glycine	142-149	adrenoceptor beta 2	Homo sapiens	77-87
21572694-1	2011	BACKGROUND AND OBJECTIVES: Two polymorphisms of beta(2)-adrenergic receptor (beta(2)-AR) gene, namely the substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic (Glu) at codon 27, are linked with functional changes in the beta(2)-AR in the respiratory system even though they are not deemed to be susceptibility genes for asthma per se.	Glycine	151-154	adrenoceptor beta 2	Homo sapiens	48-75
21572694-1	2011	BACKGROUND AND OBJECTIVES: Two polymorphisms of beta(2)-adrenergic receptor (beta(2)-AR) gene, namely the substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic (Glu) at codon 27, are linked with functional changes in the beta(2)-AR in the respiratory system even though they are not deemed to be susceptibility genes for asthma per se.	Glycine	151-154	adrenoceptor beta 2	Homo sapiens	77-87
21276770-0	2011	Induction of integrin beta3 in PGE2-stimulated adhesion of mastocytoma P-815 cells to the Arg-Gly-Asp-enriched fragment of fibronectin.	Glycine	94-97	integrin beta 3	Mus musculus	13-27
21765176-0	2012	Substitution of a conserved glycine in the PHR domain of Arabidopsis cryptochrome 1 confers a constitutive light response.	Glycine	28-35	cryptochrome 1	Arabidopsis thaliana	69-83
21765176-3	2012	Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis.	Glycine	50-53	cryptochrome 1	Arabidopsis thaliana	21-25
21765176-3	2012	Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis.	Glycine	50-53	cryptochrome 1	Arabidopsis thaliana	157-161
21765176-3	2012	Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis.	Glycine	50-53	cryptochrome 1	Arabidopsis thaliana	157-161
22509268-7	2012	Analysis of DRB1 and DQB1 protein chain residues showed that the Val/Gly residue at position 86 of the DRB1 chain was the only difference between the protective *16:01- *15:02 alleles and the predisposing *15:01 one.	Glycine	69-72	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	21-25
7825573-5	1995	The deficiency is assigned to the XP-D complementation group, and we have identified two causative mutations in the XPD gene: a gly-->arg change at amino acid 675 in the allele inherited from the patient"s mother and a -1 frameshift at amino acid 669 in the allele inherited from his father.	Glycine	128-131	ERCC excision repair 2, TFIIH core complex helicase subunit	Homo sapiens	34-38
20725951-1	2011	The structural influence of a single Gly residue inserted into an Aib(16) homooligomer was studied in the solid state by X-ray crystallography.	Glycine	37-40	ANIB1	Homo sapiens	66-69
7825573-5	1995	The deficiency is assigned to the XP-D complementation group, and we have identified two causative mutations in the XPD gene: a gly-->arg change at amino acid 675 in the allele inherited from the patient"s mother and a -1 frameshift at amino acid 669 in the allele inherited from his father.	Glycine	128-131	ERCC excision repair 2, TFIIH core complex helicase subunit	Homo sapiens	116-119
7537125-7	1994	External calcium ion and temperature dependence of adhesion together with the observation that RGD (Arg, Gly, Asp)--containing peptide blocked cell binding to FN suggests that FC epsilon RI crosslinking-induced adhesion potentiation involves an integrin type receptor on cell surface.	Glycine	105-108	fibronectin 1	Mus musculus	159-161
21731704-1	2011	Glycine transporter-1 (GlyT-1) in glial cells regulates extracellular levels of glycine, which acts as an obligatory co-agonist at the N-methyl-D-aspartate (NMDA) receptors in the brain.	Glycine	80-87	solute carrier family 6 member 9	Rattus norvegicus	0-21
21731704-1	2011	Glycine transporter-1 (GlyT-1) in glial cells regulates extracellular levels of glycine, which acts as an obligatory co-agonist at the N-methyl-D-aspartate (NMDA) receptors in the brain.	Glycine	80-87	solute carrier family 6 member 9	Rattus norvegicus	23-29
21989967-7	2012	The structure of the Aib-Gly turn containing hairpin was determined by NMR and was shown to be like trpzip2 (Asn-Gly turn) as regards turn and strand geometries, but to differ from trpzip1 (Gly-Asn turn).	Glycine	25-28	ANIB1	Homo sapiens	21-24
21989967-7	2012	The structure of the Aib-Gly turn containing hairpin was determined by NMR and was shown to be like trpzip2 (Asn-Gly turn) as regards turn and strand geometries, but to differ from trpzip1 (Gly-Asn turn).	Glycine	113-116	ANIB1	Homo sapiens	21-24
21989967-7	2012	The structure of the Aib-Gly turn containing hairpin was determined by NMR and was shown to be like trpzip2 (Asn-Gly turn) as regards turn and strand geometries, but to differ from trpzip1 (Gly-Asn turn).	Glycine	113-116	ANIB1	Homo sapiens	21-24
21738582-0	2011	N-terminal Gly(224)-Gly(411) domain in Listeria adhesion protein interacts with host receptor Hsp60.	Glycine	11-14	heat shock protein family D (Hsp60) member 1	Homo sapiens	94-99
21738582-0	2011	N-terminal Gly(224)-Gly(411) domain in Listeria adhesion protein interacts with host receptor Hsp60.	Glycine	20-23	heat shock protein family D (Hsp60) member 1	Homo sapiens	94-99
7954938-1	1994	The tissue-type plasminogen activator (t-PA)-releasing action of synthetic dipeptides containing Gly, Ser or Pro was investigated.	Glycine	97-100	plasminogen activator, tissue type	Rattus norvegicus	39-43
21797820-13	2011	The expression levels of ROCK1, PTEN, and caspase-8, -9, and -3 were upregulated significantly in Gly group, and their expression was reduced in the fasudil group.	Glycine	98-101	Rho-associated coiled-coil containing protein kinase 1	Rattus norvegicus	25-30
21797820-13	2011	The expression levels of ROCK1, PTEN, and caspase-8, -9, and -3 were upregulated significantly in Gly group, and their expression was reduced in the fasudil group.	Glycine	98-101	phosphatase and tensin homolog	Rattus norvegicus	32-36
21797820-13	2011	The expression levels of ROCK1, PTEN, and caspase-8, -9, and -3 were upregulated significantly in Gly group, and their expression was reduced in the fasudil group.	Glycine	98-101	caspase 8	Rattus norvegicus	42-63
21967108-2	2011	PICS profiling of cathepsin B endopeptidase specificity highlights strong selectivity for glycine in P3" due to an occluding loop blocking access to the primed subsites.	Glycine	90-97	cathepsin B	Homo sapiens	18-29
21971830-5	2011	Thus, after hours or days of relaxin treatment, respectively, arterial MMP-9 or MMP-2 hydrolyze "big" endothelin (ET) at a gly-leu bond to form ET(1-32), which in turn activates the endothelial ET(B) receptor/nitric oxide vasodilatory pathway.	Glycine	123-126	matrix metallopeptidase 9	Rattus norvegicus	71-76
8062449-9	1994	Results of mapping discrete epitopes using glycine substitution within overlapping 7-mers of beta 2m linear sequence compared with site-specific mutation of single beta 2m residues were similar in many instances, but also often showed marked differences.	Glycine	43-50	beta-2-microglobulin	Homo sapiens	93-100
22037576-2	2011	Recently we have demonstrated that a local force applied via Arg-Gly-Asp (RGD) peptides coated magnetic beads to mouse embryonic stem (ES) cells increases cell spreading and cell stiffness and decreases Oct3/4 (Pou5f1) gene expression.	Glycine	65-68	POU domain, class 5, transcription factor 1	Mus musculus	203-209
22037576-2	2011	Recently we have demonstrated that a local force applied via Arg-Gly-Asp (RGD) peptides coated magnetic beads to mouse embryonic stem (ES) cells increases cell spreading and cell stiffness and decreases Oct3/4 (Pou5f1) gene expression.	Glycine	65-68	POU domain, class 5, transcription factor 1	Mus musculus	211-217
21159159-1	2010	BACKGROUND: Collagen-like surface proteins Scl1 and Scl2 on Streptococcus pyogenes contain contiguous Gly-X-X triplet amino acid motifs, the characteristic structure of human collagen.	Glycine	102-105	Serum cholesterol level QTL 1	Rattus norvegicus	43-47
7520695-1	1994	The aim of the present work was to further determine how the T-protein of the glycine-cleavage system and serine hydroxy-methyltransferase (SHMT), two folate-dependent enzymes from pea leaf mitochondria, interact through a common pool of tetrahydrofolate polyglutamates (H4PteGlun).	Glycine	78-85	serine hydroxymethyltransferase 1	Homo sapiens	106-138
20162668-2	2010	The aim of our study was to evaluate the combined effects of MSI, BRAF(V600E) and specific KRAS mutation (Gly   Asp; G12D, Gly   Asp, G13D; Gly   Val; G12V) on prognosis in 404 sporadic and 94 hereditary CRC patients.	Glycine	106-109	KRAS proto-oncogene, GTPase	Homo sapiens	91-95
20977478-3	2010	Our previous quantitative trait loci analysis using C57BL/6 (B6) mice with better PPI performance and C3H/He (C3) with lower PPI score, shows that genes for both D-serine synthesizing enzyme and enzyme for reversible conversion between glycine and L-serine (Srr and Shmt1, respectively) are located in the same PPI-quantitative trait loci peak.	Glycine	236-243	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	266-271
21911617-2	2011	Unlike other ubiquitously expressed KCC isoforms, expression of KCC2 is widely considered to be restricted to neurons, where it is responsible for maintaining a low intracellular chloride concentration to drive hyperpolarising postsynaptic responses to the inhibitory neurotransmitters GABA and glycine.	Glycine	295-302	solute carrier family 12 member 5	Homo sapiens	64-68
7520695-1	1994	The aim of the present work was to further determine how the T-protein of the glycine-cleavage system and serine hydroxy-methyltransferase (SHMT), two folate-dependent enzymes from pea leaf mitochondria, interact through a common pool of tetrahydrofolate polyglutamates (H4PteGlun).	Glycine	78-85	serine hydroxymethyltransferase 1	Homo sapiens	140-144
21920385-6	2011	D-serine modestly decreased levels of glycine, which were enhanced by administration of glycine itself and of the glycine transporter-1 inhibitor, sarcosine.	Glycine	38-45	solute carrier family 6 member 9	Rattus norvegicus	114-135
7520695-5	1994	In a matrix extract from pea leaf mitochondria, the maximal activity of the glycine-cleavage system was about 2.5 times higher than the maximal activity of SHMT.	Glycine	76-83	serine hydroxymethyltransferase 1	Homo sapiens	156-160
21822533-5	2011	siRNA-mediated reduction of fibronectin and interference in the liaison between fibronectin and integrins by the Arg-Gly-Asp-Ser (RGDS) peptide increased aggrecan expression, and decreased versican expression by TGF-beta1 stimulation.	Glycine	117-120	ral guanine nucleotide dissociation stimulator	Mus musculus	130-134
8078461-2	1994	The predicted protein (termed RGP-2) is 259 amino acids in length and consists of an N-terminal sequence of 39 amino acids, a consensus sequence type RNA-binding domain of 82 amino acids, a glycine-rich domain of 83 amino acids and an acidic C-terminal domain of 46 amino acids.	Glycine	190-197	glycine-rich RNA-binding protein 4, mitochondrial-like	Nicotiana tabacum	30-35
21790607-0	2011	Glycine release provoked by disturbed Na+, Na+ and Ca2+ homeostasis in cerebellar nerve endings: roles of Ca2+ channels, Na+/Ca2+ exchangers and GlyT2 transporter reversal.	Glycine	0-7	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	145-150
21790607-1	2011	Glycine release provoked by ion dysregulations typical of some neuropathological conditions was analyzed in cerebellar synaptosomes selectively pre-labelled with [3H]glycine through GlyT2 transporters and exposed in superfusion to KCl, 4-aminopyridine (4-AP) or veratridine.	Glycine	0-7	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	182-187
20881039-8	2010	The sizes of the tryptic phosphopeptides derived from Nup62 were compatible with sites in the Phe/Gly repeat domain which display common consensus sequences for ERK and p38 substrates.	Glycine	98-101	nucleoporin 62	Homo sapiens	54-59
7914194-4	1994	The predicted HB9 protein has a molecular mass of 41 kilodaltons and is enriched for alanine, glycine, and leucine.	Glycine	94-101	motor neuron and pancreas homeobox 1	Homo sapiens	14-17
20926573-0	2010	Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response.	Glycine	0-7	influenza virus NS1A binding protein	Mus musculus	37-40
20958070-1	2010	Peptidylglycine alpha-hydroxylating monooxygenase (PHM) catalyzes the stereospecific hydroxylation of the Calpha of C-terminal glycine-extended peptides and proteins, the first step in the activation of many peptide hormones, growth factors, and neurotransmitters.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	51-54
21787820-6	2011	Mass spectrometry analysis of the purified rAp-S (3085.80Da) showed the addition of a glycine residue on its N-terminal end derived from vector design and peptide purification.	Glycine	86-93	LDL receptor related protein associated protein 1	Rattus norvegicus	43-46
21787820-6	2011	Mass spectrometry analysis of the purified rAp-S (3085.80Da) showed the addition of a glycine residue on its N-terminal end derived from vector design and peptide purification.	Glycine	86-93	LDL receptor related protein associated protein 1	Rattus norvegicus	1-2
7798168-10	1994	111, 2341-2351 (1990)] have reported that Pro-11, Gly-170, and Ile-340 in normal human AGT1 were replaced by Leu, Arg, and Met, respectively, in a patient with primary hyperoxaluria type 1.	Glycine	50-53	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	87-91
21721535-4	2011	To address this question, we created covalently linked S100A4 dimers using a glycine rich flexible linker.	Glycine	77-84	S100 calcium binding protein A4	Homo sapiens	55-61
21807943-2	2011	CB mutations cause X-linked mental retardation due to defective clustering of gephyrin, a postsynaptic protein associated with both glycine and GABA(A) receptors.	Glycine	132-139	Cdc42 guanine nucleotide exchange factor 9	Homo sapiens	0-2
21072201-7	2010	Moreover, the nonsynonymous CEP68 rs7572857G&gt;A variant that replaces glycine with serine showed a higher decline of forced expiratory volume in 1s (FEV(1)) by aspirin provocation than other variants (P = 3.0x10(-5)).	Glycine	72-79	centrosomal protein 68	Homo sapiens	28-33
8058050-2	1994	At NR1A/NR2B receptors, in the presence of a saturating concentration of glycine, the magnitude of spermine stimulation was dependent on the concentration of NMDA or glutamate.	Glycine	73-80	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	8-12
20805357-5	2010	Moreover, HCF-1 interacts with the middle region of YY1 encompassing the glycine-lysine-rich domain and is essential for the formation of a ternary complex with YY1 and BAP1 in vivo.	Glycine	73-80	host cell factor C1	Homo sapiens	10-15
20727678-4	2010	In all models Gly/GABA neurons were activated as indicated by their expression of c-fos.	Glycine	14-17	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	82-87
21771585-5	2011	The Michaelis-Menten constant (K(m)) was determined for all three substrates (glycine, GAB and ATP): glycine K(m) increased by 30-115-fold, GAB K(m) decreased by 8-17-fold, and the ATP K(m) was unchanged.	Glycine	78-85	alpha-1-B glycoprotein	Homo sapiens	140-143
7516705-5	1994	At saturating glycine concentrations, an average of 70% of the whole-cell current amplitude was associated with form A alpha and 30% with A beta.	Glycine	14-21	amyloid beta (A4) precursor protein	Mus musculus	138-144
21707028-0	2011	A highly selective redox, chromogenic, and fluorescent chemosensor for Hg2+ in aqueous solution based on ferrocene-glycine bioconjugates.	Glycine	115-122	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	71-74
7516705-11	1994	In the presence of 100 microM glycine, the apparent dissociation constant for the inhibitor picrotoxinin from receptor form A alpha was 80 microM, and that from A beta was 460 microM.	Glycine	30-37	amyloid beta (A4) precursor protein	Mus musculus	161-167
8204663-9	1994	The site of glycation of bovine gamma-II-crystallin by fructose was thereby identified as the alpha-NH2 group of the N-terminal glycine.	Glycine	128-135	G protein subunit gamma 7	Bos taurus	32-40
21489996-8	2011	By developing RhSP-D mutants that also have the pSP-D-specific Ser-Gly-Ala loop inserted in the CRD, we could demonstrate that the N-linked glycan-mediated interactions between pSP-D and IAV involves additional structural prerequisites of the pSP-D CRD.	Glycine	67-70	surfactant protein D	Homo sapiens	48-53
21489996-8	2011	By developing RhSP-D mutants that also have the pSP-D-specific Ser-Gly-Ala loop inserted in the CRD, we could demonstrate that the N-linked glycan-mediated interactions between pSP-D and IAV involves additional structural prerequisites of the pSP-D CRD.	Glycine	67-70	surfactant protein D	Homo sapiens	177-182
21489996-8	2011	By developing RhSP-D mutants that also have the pSP-D-specific Ser-Gly-Ala loop inserted in the CRD, we could demonstrate that the N-linked glycan-mediated interactions between pSP-D and IAV involves additional structural prerequisites of the pSP-D CRD.	Glycine	67-70	surfactant protein D	Homo sapiens	177-182
20828175-1	2010	Glycine-derived 1H-benzo[e][1,4]diazepin-2(3H)-ones (BZDs) 5d-g featuring C9- and N1- substitution exhibit enantiomerization barriers too high to be measured by (1)H NMR coalescence experiments.	Glycine	0-7	complement C9	Homo sapiens	74-84
20558222-3	2010	[(14)C]Glycine uptake by TR-MUL5 cells was Na(+)- and Cl(-)-dependent, and a saturable process with Michaelis-Menten constants of 48.6 microM and 4.53 mM, and inhibited by glycine transporter 1 (GlyT1) and system A substrates.	Glycine	7-14	solute carrier family 6 member 9	Rattus norvegicus	172-193
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	151-155
21446907-2	2011	MMP-9 selectively cleaves Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys peptide.	Glycine	30-33	matrix metallopeptidase 9	Homo sapiens	0-5
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	glutamate receptor, ionotropic, N-methyl D-aspartate 2C L homeolog	Xenopus laevis	207-211
21446907-3	2011	MMP-9 enzyme recognizes a peptide sequence Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys and cleaves the peptide into two parts.	Glycine	47-50	matrix metallopeptidase 9	Homo sapiens	0-5
8170953-3	1994	For this purpose, we have investigated the role of Gly-13, which is located in the active site sequence Arg9-His10-Gly11-Glu12-Gly13 in human BPGM.	Glycine	51-54	bisphosphoglycerate mutase	Homo sapiens	142-146
21446907-3	2011	MMP-9 enzyme recognizes a peptide sequence Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys and cleaves the peptide into two parts.	Glycine	71-74	matrix metallopeptidase 9	Homo sapiens	0-5
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	9-16	solute carrier family 6 member 9	Rattus norvegicus	98-124
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	9-16	solute carrier family 6 member 9	Rattus norvegicus	126-131
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	9-16	solute carrier family 6 member 9	Rattus norvegicus	146-151
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	71-78	solute carrier family 6 member 9	Rattus norvegicus	98-124
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	71-78	solute carrier family 6 member 9	Rattus norvegicus	126-131
21348870-4	2011	The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it.	Glycine	71-78	solute carrier family 6 member 9	Rattus norvegicus	146-151
20558222-3	2010	[(14)C]Glycine uptake by TR-MUL5 cells was Na(+)- and Cl(-)-dependent, and a saturable process with Michaelis-Menten constants of 48.6 microM and 4.53 mM, and inhibited by glycine transporter 1 (GlyT1) and system A substrates.	Glycine	7-14	solute carrier family 6 member 9	Rattus norvegicus	195-200
20558222-6	2010	These uptake studies suggest that GlyT1 and system A are involved in [(14)C]glycine uptake for the high- and low-affinity processes, respectively, in TR-MUL5 cells.	Glycine	76-83	solute carrier family 6 member 9	Rattus norvegicus	34-39
20558222-11	2010	In conclusion, GlyT1 and CAT1 most likely mediate glycine and L-arginine uptake, respectively, by Muller cells and are expected to play an important role in supplying precursors for creatine biosynthesis in Muller cells.	Glycine	50-57	solute carrier family 6 member 9	Rattus norvegicus	15-20
20447457-5	2010	Since GABA and glycine use the same vesicular inhibitory amino acid transporter (VIAAT or VGAT) we also analysed GABAergic neurotransmission.	Glycine	15-22	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	81-86
8170953-4	1994	This sequence is similar to the Arg-His-Gly-Xaa-Arg* sequence of the distantly related acid phosphatases, which catalyze as BPGM similar phosphoryl transfers but to a greater extent.	Glycine	40-43	bisphosphoglycerate mutase	Homo sapiens	124-128
7911663-3	1994	It is shown that the bovine retinal guanylate kinase like the analogous enzyme from yeast Saccharomyces cerevisiae contains a characteristic glycine-rich motif, involved in ATP binding.	Glycine	141-148	guanylate kinase 1	Bos taurus	36-52
20620253-6	2010	Addition of 0.04% (w/v) polyvinyl alcohol 50K and 1 mM dithiothreitol to the glycine buffer (pH 8.4) gave long-term stability and higher yields of SSS and SBE, due to activation of inactive enzymes.	Glycine	77-84	1,4-alpha-glucan-branching enzyme	Solanum tuberosum	155-158
21378158-3	2011	The MYO7A(G2164C) mutation predicts a nonconservative glycine-to-arginine (G722R) amino acid substitution at a highly conserved glycine residue.	Glycine	54-61	myosin VIIA	Homo sapiens	4-9
21378158-3	2011	The MYO7A(G2164C) mutation predicts a nonconservative glycine-to-arginine (G722R) amino acid substitution at a highly conserved glycine residue.	Glycine	128-135	myosin VIIA	Homo sapiens	4-9
8166285-14	1994	High concentrations of glycine-extended gastrin-17 (GG) (&gt; 10(-6) M) were mitogenic for a gastrin-responsive human colon cancer (DLD-1) cell line in vitro.	Glycine	23-30	gastrin	Homo sapiens	40-47
21296884-6	2011	We showed that glycine 22 and proline 27 in hydrophobic domain 1 of Pen-2 are essential for complex formation and stability of gamma-secretase.	Glycine	15-22	presenilin enhancer, gamma-secretase subunit	Homo sapiens	68-73
20430876-4	2010	Saturable Gly-Sar uptake in Slc15a1(-/-) everted sac preparations was no longer detectable.	Glycine	10-13	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	28-35
8166285-14	1994	High concentrations of glycine-extended gastrin-17 (GG) (&gt; 10(-6) M) were mitogenic for a gastrin-responsive human colon cancer (DLD-1) cell line in vitro.	Glycine	23-30	gastrin	Homo sapiens	93-100
21291263-4	2011	The PTP1B catalytic domain has modest preference for acidic residues on both sides of pY, is highly active toward multiply phosphorylated peptides, but disfavors basic residues at any position, a Gly at the pY-1 position, or a Pro at the pY+1 position.	Glycine	196-199	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	4-9
8125181-3	1994	We demonstrate the developmental expression and thyroid hormone induction of magainin and PGLa (peptide with aminoterminal glycine and carboxyterminal leucinamide), the two most abundant members of the magainin peptide family.	Glycine	123-130	magainins L homeolog	Xenopus laevis	77-85
21406592-5	2011	Under basal conditions, the common Gly(875) variant of ATP7B is targeted to the trans-Golgi network (TGN) and transports copper into the TGN lumen.	Glycine	35-38	ATPase copper transporting beta	Homo sapiens	55-60
20523114-7	2010	The C-terminal glycine residue of LGG-2 is essential for post-translational modification and localization to the autophagosomes.	Glycine	15-22	Protein lgg;Protein lgg-2	Caenorhabditis elegans	34-39
7509863-3	1994	Treatment of hippocampal neurons with glutamate/glycine (Glu/Gly), ionomycin, or 12-O-tetradecanoylphorbol 13-acetate (TPA) increased 32P labeling of immunoprecipitated alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionate (AMPA)-type GluRs by 145%, 180%, and 227%, respectively, of control values.	Glycine	48-55	glutamyl-tRNA synthetase 2, mitochondrial	Homo sapiens	235-240
20471275-2	2010	Our previous studies showed that the high-affinity HSP47-binding motif in the collagen triple helix is Xaa-(Thr/Pro)-Gly-Xaa-Arg-Gly.	Glycine	117-120	serpin family H member 1	Homo sapiens	51-56
20200225-4	2010	Mutation analyses of MyoK revealed that both a C-terminal farnesylation membrane anchor and a Gly-Pro-Arg domain that interacts with profilin and Abp1 were necessary for proper localization in the furrow and efficient phagocytosis.	Glycine	94-97	profilin	Saccharomyces cerevisiae S288C	133-141
21323335-0	2011	Substituent effects on electrophilic catalysis by the carbonyl group: anatomy of the rate acceleration for PLP-catalyzed deprotonation of glycine.	Glycine	138-145	proteolipid protein 1	Homo sapiens	107-110
21044902-0	2011	A novel ACVR1 mutation in the glycine/serine-rich domain found in the most benign case of a fibrodysplasia ossificans progressiva variant reported to date.	Glycine	30-37	activin A receptor type 1	Homo sapiens	8-13
7509863-3	1994	Treatment of hippocampal neurons with glutamate/glycine (Glu/Gly), ionomycin, or 12-O-tetradecanoylphorbol 13-acetate (TPA) increased 32P labeling of immunoprecipitated alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionate (AMPA)-type GluRs by 145%, 180%, and 227%, respectively, of control values.	Glycine	61-64	glutamyl-tRNA synthetase 2, mitochondrial	Homo sapiens	235-240
21044902-2	2011	Here we describe a novel c.587 T &gt; C mutation in the glycine/serine-rich domain of ACVR1, associated with delayed onset of heterotopic ossification and an exceptionally mild clinical course.	Glycine	56-63	activin A receptor type 1	Homo sapiens	86-91
7509863-8	1994	Phosphorylation of GluRs in response to Glu/Gly was blocked by a specific NMDA receptor/ion channel antagonist (DL-2-amino-5-phosphonovaleric acid) or by a cell-permeable inhibitor of CaM-kinase II (1-[N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4- phenylpiperazine, KN-62).	Glycine	44-47	glutamyl-tRNA synthetase 2, mitochondrial	Homo sapiens	19-24
20460875-1	2010	Monovalent bile acids, such as taurine- and glycine-conjugated bile acids, are excreted into bile by bile salt export pumps (BSEP, ABCB11).	Glycine	44-51	ATP binding cassette subfamily B member 11	Homo sapiens	125-129
8114711-2	1994	MZF1 contains 13 C2H2 zinc fingers arranged in two domains which are separated by a short glycine- and proline-rich sequence.	Glycine	90-97	myeloid zinc finger 1	Homo sapiens	0-4
20460875-1	2010	Monovalent bile acids, such as taurine- and glycine-conjugated bile acids, are excreted into bile by bile salt export pumps (BSEP, ABCB11).	Glycine	44-51	ATP binding cassette subfamily B member 11	Homo sapiens	131-137
20184307-2	2010	Radiolabeled RGD (Arg-Gly-Asp) peptides that specifically target integrin alphavbeta3 have great potential for tumor early detection and noninvasively monitoring the status of tumor angiogenesis.	Glycine	22-25	integrin subunit alpha V	Homo sapiens	65-85
21278231-9	2011	Like in S. cerevisiae, mutation of the conserved glycine at position 343 in Mep2 of C. albicans to cysteine resulted in Npr1-independent ammonium uptake.	Glycine	49-56	ammonium permease MEP2	Saccharomyces cerevisiae S288C	76-80
21278231-9	2011	Like in S. cerevisiae, mutation of the conserved glycine at position 343 in Mep2 of C. albicans to cysteine resulted in Npr1-independent ammonium uptake.	Glycine	49-56	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	120-124
21382783-4	2011	Here we report a female patient with mild dystrophic epidermolysis bullosa harbouring two compound heterozygous COL7A1 mutations, namely the intronic splice site mutation c.3832-2A &gt; G and the glycine substitution p.G1347W.	Glycine	196-203	collagen type VII alpha 1 chain	Homo sapiens	112-118
8106414-7	1994	From the sequence, we deduced that the DSP cDNA coded for 366 amino acids, predominantly Asp, Ser, Glu, and Gly.	Glycine	108-111	dentin sialophosphoprotein	Rattus norvegicus	39-42
8276107-6	1994	In contrast, COS-7 cells produced glycine-extended gastrin and only a small amount of amidated gastrin.	Glycine	34-41	gastrin	Homo sapiens	51-58
21205613-6	2011	The deletion of HPR3 by T-DNA insertion mutagenesis results in slightly altered leaf concentrations of the photorespiratory intermediates HP, glycerate, and glycine, indicating a disrupted photorespiratory flux, but not in visible alteration of the phenotype.	Glycine	157-164	D-isomer specific 2-hydroxyacid dehydrogenase family protein	Arabidopsis thaliana	16-20
20641535-0	2004	(111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1).	Glycine	13-16	gastrin releasing peptide	Homo sapiens	81-89
20641535-0	2004	(111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1).	Glycine	13-16	gastrin releasing peptide	Homo sapiens	153-178
20641535-0	2004	(111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1).	Glycine	13-16	gastrin releasing peptide	Homo sapiens	180-183
20053354-0	2010	Glycine-rich loop of mitochondrial processing peptidase alpha-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20.	Glycine	0-7	Tom20p	Saccharomyces cerevisiae S288C	162-167
7507399-2	1994	Chronic DDC treatment resulted in elevations of LHRH-Gly like immunoreactivity in the preoptic area (POA) and the medial basal hypothalamus (MBH), as well as elevations in SP-Gly like immunoreactivity in all areas of the CNS examined.	Glycine	53-56	gonadotropin releasing hormone 1	Rattus norvegicus	48-52
19508199-1	2010	he photo-switchable insect kinin thioxo-analog Phe(1)-Tyr(2)-Psi[CS-N]-Pro(3)-Trp(4)-Gly(5)-NH(2) (Psi[CS-N](2)-Kinin) can change from ground state to photo-stationary state by following a pulse of UV Radiation and its bioactivity increases simultaneously.	Glycine	85-88	transient receptor potential cation channel subfamily C member 4	Homo sapiens	78-83
20032456-5	2010	The mutated glycine is in the pore-lining transmembrane helix of Kir6.2; an equivalent glycine in other potassium channels has been proposed to serve as a hinge to allow helix bending during gating.	Glycine	87-94	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	65-71
21185009-5	2011	c.265T&gt;G results in a substitution of glycine for cysteine (p.Cys89Gly), and this substitution cosegregates with deafness in the six DFNB74 families.	Glycine	41-48	methionine sulfoxide reductase B3	Homo sapiens	136-142
22553674-7	2011	Bi-directional sequencing of the transthyretin gene revealed a single base-pair substitution, which results in an amino acid substitution at position83, glycine to arginine (transthyretin Arg-83).	Glycine	153-160	transthyretin	Homo sapiens	33-46
22553674-7	2011	Bi-directional sequencing of the transthyretin gene revealed a single base-pair substitution, which results in an amino acid substitution at position83, glycine to arginine (transthyretin Arg-83).	Glycine	153-160	transthyretin	Homo sapiens	174-187
7905294-1	1993	Maximal L-glutamate/glycine-evoked currents were inhibited by ethanol in Xenopus laevis oocytes expressing recombinant heteromeric NMDA receptors consisting of NR1-NR2A, NR1-NR2B, and NR1-NR2C subunit combinations.	Glycine	20-27	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	160-163
20939853-8	2011	Preoperative glycine injection significantly reduced the induction of interleukin-6 (IL-6), tumor necrosis factor-alpha, inducible nitric oxide synthase and intercellular adhesion molecule-1 mRNAs, which was associated with the attenuation in postoperative leukocyte recruitment.	Glycine	13-20	intercellular adhesion molecule 1	Homo sapiens	157-190
7905294-1	1993	Maximal L-glutamate/glycine-evoked currents were inhibited by ethanol in Xenopus laevis oocytes expressing recombinant heteromeric NMDA receptors consisting of NR1-NR2A, NR1-NR2B, and NR1-NR2C subunit combinations.	Glycine	20-27	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	170-173
7905294-1	1993	Maximal L-glutamate/glycine-evoked currents were inhibited by ethanol in Xenopus laevis oocytes expressing recombinant heteromeric NMDA receptors consisting of NR1-NR2A, NR1-NR2B, and NR1-NR2C subunit combinations.	Glycine	20-27	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	174-178
7905294-1	1993	Maximal L-glutamate/glycine-evoked currents were inhibited by ethanol in Xenopus laevis oocytes expressing recombinant heteromeric NMDA receptors consisting of NR1-NR2A, NR1-NR2B, and NR1-NR2C subunit combinations.	Glycine	20-27	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	170-173
21698173-9	2011	CONCLUSIONS/SIGNIFICANCE: Our results suggest that TM5 (Ile-295, Gly-297) is in close proximity to TM8 (Ile-463) in the mammalian transporter, and that the spatial relationship between these domains is altered during the transport cycle.	Glycine	65-68	tropomyosin 3	Homo sapiens	51-54
8307321-8	1993	In contrast to other collagens, glycine replacement mutations in the Gly-X-Y repeats of sqt-1 cause very mild phenotypes.	Glycine	32-39	Cuticle collagen sqt-1	Caenorhabditis elegans	88-93
21698173-9	2011	CONCLUSIONS/SIGNIFICANCE: Our results suggest that TM5 (Ile-295, Gly-297) is in close proximity to TM8 (Ile-463) in the mammalian transporter, and that the spatial relationship between these domains is altered during the transport cycle.	Glycine	65-68	tetraspanin 16	Homo sapiens	99-102
20050636-2	2010	Unrestrained molecular dynamics simulation of a 3(10)-helical peptide, Z-Aib-L-Leu-(Aib)(2)-Gly-OtBu, in CDCl(3) is performed using the AMBER ff99SB force field, and the linear and two-dimensional infrared (2D IR) spectra are simulated on the basis of a vibrational exciton Hamiltonian model.	Glycine	92-95	ANIB1	Homo sapiens	73-76
20050636-2	2010	Unrestrained molecular dynamics simulation of a 3(10)-helical peptide, Z-Aib-L-Leu-(Aib)(2)-Gly-OtBu, in CDCl(3) is performed using the AMBER ff99SB force field, and the linear and two-dimensional infrared (2D IR) spectra are simulated on the basis of a vibrational exciton Hamiltonian model.	Glycine	92-95	ANIB1	Homo sapiens	84-87
8307321-8	1993	In contrast to other collagens, glycine replacement mutations in the Gly-X-Y repeats of sqt-1 cause very mild phenotypes.	Glycine	69-72	Cuticle collagen sqt-1	Caenorhabditis elegans	88-93
20947499-2	2010	The monomeric precursor, tropoelastin, is highly hydrophobic yet remains substantially disordered and flexible in solution, due in large part to a high combined threshold of proline and glycine residues within hydrophobic sequences.	Glycine	186-193	elastin	Homo sapiens	25-37
19893491-3	2010	Here we show that CYLD controls cell growth and division at the G(1)/S-phase as well as cytokinesis by associating with alpha-tubulin and microtubules through its CAP-Gly domains.	Glycine	167-170	CYLD lysine 63 deubiquitinase	Homo sapiens	18-22
8129867-1	1993	We previously reported a complete computer-based three-dimensional structure for residues 1-171 of the Gly 12-containing ras-gene-encoded p21 protein complexed with GDP.	Glycine	103-106	H3 histone pseudogene 16	Homo sapiens	138-141
19365639-5	2010	The p.G366V is a novel mutation of the DHCR7 gene with guanine by thymine nucleotide exchange resulting in glycin by valin amino acid exchange in the dehydrocholesterol reductase enzyme.	Glycine	107-113	7-dehydrocholesterol reductase	Homo sapiens	39-44
20923770-7	2010	SER1 and SER2 encode two enzymes of the major serine biosynthetic pathway, and the Arn1 trafficking defect in the ser1Delta strain was corrected with supplemental serine or glycine.	Glycine	173-180	siderophore transporter	Saccharomyces cerevisiae S288C	83-87
8226835-1	1993	An expression vector for NADH-cytochrome b5 reductase containing a thrombin cleavage site directly before the N-terminal glycine residue of the flavoprotein was used to isolate the non-myristoylated enzyme by thrombin cleavage of the initial fusion protein of a short segment of the multiple cloning site of the plasmid vector and the reductase.	Glycine	121-128	cytochrome b5 type A	Homo sapiens	30-43
20665142-4	2010	However, some peptides showed a modest increase or decrease (~2-fold), whereas a glycine-rich peptide derived from the C-terminal of neurogranin (KGPGPGGPGGAGGARGGAGGGPSGD) showed a substantial increase (6-fold) in TAP1/beta2m-(/)- mice.	Glycine	81-88	neurogranin	Mus musculus	133-144
19506924-5	2010	In particular the replacement of serine 256 and isoleucine 359 in LeuT(Aa) with glycine and threonine in hGAT-1 seems to facilitate the selection of GABA as the main substrate by changing the hydrogen bonding pattern in the active site to the amino group of the substrate.	Glycine	80-87	Leucine transport, high	Homo sapiens	66-70
7508296-0	1993	The Gly/Arg-rich (GAR) domain of Xenopus nucleolin facilitates in vitro nucleic acid binding and in vivo nucleolar localization.	Glycine	4-7	nucleolin S homeolog	Xenopus laevis	41-50
19892394-1	2010	Glycine N-methyltransferase (GNMT) is a mediator in the methionine and folate cycles, and is responsible for the transfer of a methyl group from S-adenosylmethionine (SAM) to glycine forming S-adenosylhomocysteine (SAH) and sarcosine.	Glycine	175-182	glycine N-methyltransferase	Fundulus heteroclitus	0-27
19892394-1	2010	Glycine N-methyltransferase (GNMT) is a mediator in the methionine and folate cycles, and is responsible for the transfer of a methyl group from S-adenosylmethionine (SAM) to glycine forming S-adenosylhomocysteine (SAH) and sarcosine.	Glycine	175-182	glycine N-methyltransferase	Fundulus heteroclitus	29-33
19875446-1	2009	Concentrations of extracellular glycine in the central nervous system are regulated by Na(+)/Cl(-)-dependent glycine transporters, GLYT1 and GLYT2.	Glycine	32-39	solute carrier family 6 member 9	Rattus norvegicus	131-136
19877718-5	2009	Replacement of a central Gly in the neuromodulin IQ domain with a Lys at this position in PEP19 almost entirely accounts for the distinctive patterns of Ca(2+)-dependent stability changes exhibited by the two complexes.	Glycine	25-28	Purkinje cell protein 4	Homo sapiens	90-95
19800676-4	2009	METHODS: Arg/Gly status at position 16 of ADRB2 was assessed in 1182 young asthmatic patients (age, 3-22 years) from Scotland.	Glycine	13-16	adrenoceptor beta 2	Homo sapiens	42-47
21054786-9	2010	This low activity could be explained by the fact that PRTFDC1 has a Gly in the position of the proposed catalytic Asp of HPRT.	Glycine	68-71	phosphoribosyl transferase domain containing 1	Homo sapiens	54-61
21043511-1	2010	Peptidylglycine alpha-amidating monooxygenase (PAM) is a bifunctional enzyme which catalyzes the post-translational modification of inactive C-terminal glycine-extended peptide precursors to the corresponding bioactive alpha-amidated peptide hormone.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	47-50
21043511-3	2010	The first step, the copper-, ascorbate-, and O(2)-dependent stereospecific hydroxylation at the alpha-carbon of the C-terminal glycine, is catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM).	Glycine	127-134	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	152-201
21043511-3	2010	The first step, the copper-, ascorbate-, and O(2)-dependent stereospecific hydroxylation at the alpha-carbon of the C-terminal glycine, is catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM).	Glycine	127-134	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	203-206
7508296-1	1993	Epitope-tagged Xenopus nucleolin was expressed in Escherichia coli cells and in Xenopus oocytes either as a full-length wild-type protein or as a truncation that lacked the distinctive carboxy glycine/arginine-rich (GAR) domain.	Glycine	193-200	nucleolin S homeolog	Xenopus laevis	23-32
8226790-9	1993	The experimental data suggests GLYT2 might play a major role in the termination of the inhibitory effect of glycine in the brain stem and spinal cord of vertebrates.	Glycine	108-115	solute carrier family 6 member 5	Rattus norvegicus	31-36
20691713-13	2010	Glycine produced concentration-dependent decreases in binding affinity of both radioligands without major changes in B(max) values, suggesting that both [(3)H]-SB-733993 and [(3)H]-GSK931145 bind to sites on GlyT-1 that are orthosteric to the site at which glycine itself binds.	Glycine	0-7	solute carrier family 6 member 9	Rattus norvegicus	208-214
8218401-5	1993	Mouse fibrillarin contains a N-terminal glycine- and arginine-rich (GAR) domain which although conserved among the fibrillarins is not as strongly conserved as several regions in the carboxy tail of the protein.	Glycine	40-47	fibrillarin	Mus musculus	6-17
21061495-2	2004	Ligands such as vitronectin, fibronectin, etc., which interact with integrins, are known to bind these receptors through an Arg-Gly-Asp (RGD) epitope.	Glycine	128-131	vitronectin	Homo sapiens	16-27
19666071-4	2009	[(14)C]Glycine uptake by TR-iBRB2 cells was Na(+)- and Cl(-)-dependent, and concentration-dependent with Michaelis-Menten constants of 55.4 microM and 8.02 mM, and inhibited by glycine transporter 1 (GlyT1) and system A inhibitors.	Glycine	7-14	solute carrier family 6 member 9	Rattus norvegicus	177-198
19666071-4	2009	[(14)C]Glycine uptake by TR-iBRB2 cells was Na(+)- and Cl(-)-dependent, and concentration-dependent with Michaelis-Menten constants of 55.4 microM and 8.02 mM, and inhibited by glycine transporter 1 (GlyT1) and system A inhibitors.	Glycine	7-14	solute carrier family 6 member 9	Rattus norvegicus	200-205
7901753-11	1993	However, the inhibitory effect of 1 microM ifenprodil at NR1A/NR2B receptors was reduced by increasing the concentration of glycine.	Glycine	124-131	glutamate receptor ionotropic, NMDA 2B	Xenopus laevis	62-66
19747169-5	2009	Zebrafish alpha5beta1 integrins do bind zebrafish fibronectin-1, and mutagenesis of residues on the upper surface and side of the zebrafish alpha5 subunit beta-propeller domain shows that these residues are important for the recognition of the Arg-Gly-Asp (RGD) motif and the synergy sequence [Pro-His-Ser-Arg-Asn (PHSRN)] in fibronectin.	Glycine	248-251	fibronectin 1a	Danio rerio	50-63
19747169-5	2009	Zebrafish alpha5beta1 integrins do bind zebrafish fibronectin-1, and mutagenesis of residues on the upper surface and side of the zebrafish alpha5 subunit beta-propeller domain shows that these residues are important for the recognition of the Arg-Gly-Asp (RGD) motif and the synergy sequence [Pro-His-Ser-Arg-Asn (PHSRN)] in fibronectin.	Glycine	248-251	fibronectin 1a	Danio rerio	50-61
20724480-10	2010	In contrast, Cys-369, Gly-408, Leu-546, and Glu-568 are essential for NADPH oxidase complex assembly.	Glycine	22-25	2,4-dienoyl-CoA reductase 1	Homo sapiens	70-75
21085509-3	2010	Previously, in our group, amino acid based amphiphiles i.e. Gly-Gly-His-EO2-Alk, a trimodular amphiphile (containing three domains: H-bond donor and acceptor/hydrophilic/hydrophobic domain, respectively) were reported to act as hydrogelators and that the gelation properties were related to hydrogen bonding, hydrophobic interactions and pi-pi stacking.	Glycine	60-63	ALK receptor tyrosine kinase	Homo sapiens	76-79
19666693-6	2009	The PPARD CC + PPARGC1A Gly/Gly genotypes were more frequently found in the elite endurance athletes than in national-level endurance athletes (P &lt; 0.000).	Glycine	24-27	peroxisome proliferator activated receptor delta	Homo sapiens	4-9
7692398-4	1993	A full-length cDNA clone for hnRNP G has been isolated and sequenced, and the predicted amino acid sequence for hnRNP G shows that it contains one RNP-consensus RNA binding domain (RBD) at the amino terminus and a carboxyl domain rich in serines, arginines and glycines.	Glycine	261-269	RBMX pseudogene 1	Homo sapiens	112-119
19666693-6	2009	The PPARD CC + PPARGC1A Gly/Gly genotypes were more frequently found in the elite endurance athletes than in national-level endurance athletes (P &lt; 0.000).	Glycine	28-31	peroxisome proliferator activated receptor delta	Homo sapiens	4-9
19666693-9	2009	However, a higher frequency of the PPARGC1A Gly/Gly + PPARD CC genotype is associated with elite-level endurance athletes.	Glycine	44-47	peroxisome proliferator activated receptor delta	Homo sapiens	54-59
20724821-4	2010	The new Gly-terminal residue from Atg8 is activated by Atg7 (an E1-like enzyme) then transferred to Atg3 (an E2-like enzyme) and finally conjugated with membrane-bound phosphatidylethanolamine (PE) through an amide bond.	Glycine	8-11	Atg3p	Saccharomyces cerevisiae S288C	100-104
20800579-1	2010	Experimental kinetics and computational modeling of human glutathione synthetase (hGS) support the significant role of the G-loop glycine triad (G369, G370, G371) for activity of this ATP-grasp enzyme.	Glycine	130-137	hepatocyte growth factor-regulated tyrosine kinase substrate	Homo sapiens	82-85
20542917-2	2010	Here, we present the size variation and evolution of the nucleotide-binding site (NBS)-encoding gene family and receptor-like kinase (RLK) gene family in Oryza, Glycine and Gossypium.	Glycine	161-168	TXK tyrosine kinase	Homo sapiens	112-132
20542917-2	2010	Here, we present the size variation and evolution of the nucleotide-binding site (NBS)-encoding gene family and receptor-like kinase (RLK) gene family in Oryza, Glycine and Gossypium.	Glycine	161-168	TXK tyrosine kinase	Homo sapiens	134-137
19855136-1	2009	Patients with classic fibrodysplasia ossificans progressiva, a disorder characterized by extensive extraskeletal endochondral bone formation, share a recurrent mutation (R206H) within the glycine/serine-rich domain of ACVR1/ALK2, a bone morphogenetic protein type I receptor.	Glycine	188-195	activin A receptor type 1	Homo sapiens	218-223
19452450-8	2009	Gly alone also significantly increased gene transactivation by the introduction of runt-related transcription factor-2 (Runx2) in COS7 cells transfected with NR1 and NR3A subunits, while D-Ser significantly prevented the increase by Gly without affecting the promoter activity of Runx2.	Glycine	0-3	glutamate receptor ionotropic, NMDA3A	Mus musculus	166-170
20545900-2	2010	It differs from B*51:01:01(B*510101) by one nucleotide substitution at codon 145 (CGC  GGC), resulting to one amino acid change (Arginine to Glycine).	Glycine	141-148	gamma-glutamylcyclotransferase	Homo sapiens	87-90
8341692-6	1993	In contrast, those receptor variants with the N-terminal insert (NR1(100), NR1(101), and NR1(111)) showed a lower agonist affinity and little or no spermine potentiation at saturating glycine.	Glycine	184-191	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	65-68
8341692-6	1993	In contrast, those receptor variants with the N-terminal insert (NR1(100), NR1(101), and NR1(111)) showed a lower agonist affinity and little or no spermine potentiation at saturating glycine.	Glycine	184-191	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	75-78
20945564-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
8341692-6	1993	In contrast, those receptor variants with the N-terminal insert (NR1(100), NR1(101), and NR1(111)) showed a lower agonist affinity and little or no spermine potentiation at saturating glycine.	Glycine	184-191	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	75-78
8100229-2	1993	This ligand has been named GlyCAM 1 (Gly-cosylation-dependent Cell Adhesion Molecule 1) because its adhesive interactions with the L selectin lectin domain require that the GlyCAM 1 polypeptide chain be appropriately modified with carbohydrates.	Glycine	27-30	glycosylation dependent cell adhesion molecule 1	Mus musculus	173-181
20448140-2	2010	Truncated mutants of CDSN ((mut)CDSN), which bear the N-terminal adhesive Gly/Ser-rich domain (GS domain) of the protein, abnormally accumulate as amorphous deposits at the periphery of hair follicles and in the papillary dermis of the patient skin.	Glycine	74-77	corneodesmosin	Homo sapiens	21-25
20448140-2	2010	Truncated mutants of CDSN ((mut)CDSN), which bear the N-terminal adhesive Gly/Ser-rich domain (GS domain) of the protein, abnormally accumulate as amorphous deposits at the periphery of hair follicles and in the papillary dermis of the patient skin.	Glycine	74-77	corneodesmosin	Homo sapiens	32-36
19330816-0	2009	Solution structure of a novel T-cell adhesion inhibitor derived from the fragment of ICAM-1 receptor: cyclo(1,8)-Cys-Pro-Arg-Gly-Gly-Ser-Val-Cys.	Glycine	125-128	intercellular adhesion molecule 1	Homo sapiens	85-91
19394328-6	2009	EC(50) values for glutamate at GluN1/GluN2A and glutamate and glycine at GluN1/GluN2B NMDA receptors were unaffected by the presence of ethanol.	Glycine	62-69	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	79-85
19540426-1	2009	MIF-1 (Pro-Leu-Gly-NH(2)) has potent therapeutic effects in depression and Parkinson"s disease, but its CNS sites of production are not yet clear.	Glycine	15-18	predicted gene 4924	Mus musculus	0-5
8500529-3	1993	Here we show that for the human HLA-DRB1 and HLA-DRB3 gene products this ratio is controlled by the valine/glycine dimorphism at position 86.	Glycine	107-114	major histocompatibility complex, class II, DR beta 3	Homo sapiens	45-53
20350574-4	2010	This redistribution is caused by transformation of the LC3 protein into a membrane bound form due to lipidation of the C-terminal glycine.	Glycine	130-137	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	55-58
8486681-7	1993	Analysis of three hEGF mutants, Tyr13--&gt;Leu, Tyr13--&gt;Arg, and Tyr13--&gt;Gly, by circular dichroism showed that the major structural features of hEGF were not significantly altered.	Glycine	79-82	epidermal growth factor	Homo sapiens	18-22
20185185-3	2010	GNMT is a mediator in the methionine and folate cycles, and the homotetrameric form enzymatically transfers a methyl group from S-adenosylmethionine (SAM) to glycine forming S-adenosylhomocysteine (SAH) and sarcosine.	Glycine	158-165	glycine N-methyltransferase	Fundulus heteroclitus	0-4
20375021-0	2010	Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism.	Glycine	91-98	myosin binding protein H	Homo sapiens	74-83
20375021-1	2010	Aminomethyltransferase, a component of the glycine cleavage system termed T-protein, reversibly catalyzes the degradation of the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein, resulting in the production of ammonia, 5,10-methylenetetrahydrofolate, and dihydrolipoate-bearing H-protein in the presence of tetrahydrofolate.	Glycine	43-50	myosin binding protein H	Homo sapiens	195-204
20375021-1	2010	Aminomethyltransferase, a component of the glycine cleavage system termed T-protein, reversibly catalyzes the degradation of the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein, resulting in the production of ammonia, 5,10-methylenetetrahydrofolate, and dihydrolipoate-bearing H-protein in the presence of tetrahydrofolate.	Glycine	43-50	myosin binding protein H	Homo sapiens	305-314
19463982-7	2009	A structural model of human EMG1 suggested that the D86 residue formed a salt bridge with arginine 84 that would be disrupted by the glycine (G) substitution.	Glycine	133-140	EMG1 N1-specific pseudouridine methyltransferase	Homo sapiens	28-32
19259068-2	2009	We have developed a peptide-like scaffold (regioselectively addressable functionalized template, RAFT), which holds four cyclo(-RGDfK-) (cRGD) motifs and proved that this molecule (called regioselectively addressable functionalized template-arginine-glycine-aspartic acid, RAFT-RGD) targets integrin alpha(v)beta(3) in vitro and in vivo.	Glycine	250-257	integrin subunit alpha V	Homo sapiens	291-314
20375021-1	2010	Aminomethyltransferase, a component of the glycine cleavage system termed T-protein, reversibly catalyzes the degradation of the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein, resulting in the production of ammonia, 5,10-methylenetetrahydrofolate, and dihydrolipoate-bearing H-protein in the presence of tetrahydrofolate.	Glycine	151-158	myosin binding protein H	Homo sapiens	195-204
20375021-1	2010	Aminomethyltransferase, a component of the glycine cleavage system termed T-protein, reversibly catalyzes the degradation of the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein, resulting in the production of ammonia, 5,10-methylenetetrahydrofolate, and dihydrolipoate-bearing H-protein in the presence of tetrahydrofolate.	Glycine	151-158	myosin binding protein H	Homo sapiens	305-314
8318164-2	1993	Comparison of the computed and high-resolution x-ray crystallographic structures of Gly-12 p21.	Glycine	84-87	H3 histone pseudogene 16	Homo sapiens	91-94
19157962-2	2009	The pure and amino acid (glycine) doped MHB crystals are grown by slow evaporation solution growth technique.	Glycine	25-32	MHB	Homo sapiens	40-43
8384219-9	1993	Mutation of this serine to a glycine drastically reduces phosphorylation of hVDR by CK-II, in vitro.	Glycine	29-36	casein kinase 2 alpha 1	Homo sapiens	84-89
19586842-3	2009	A missense mutation, c.1273G>A, was identified in exon 14 of the MYH7 gene in 4 members of the Chinese HCM family, which resulted a glycine (Gly) to arginine (Arg) exchange at amino acid residue 425.	Glycine	132-139	myosin heavy chain 7	Homo sapiens	65-69
19586842-3	2009	A missense mutation, c.1273G>A, was identified in exon 14 of the MYH7 gene in 4 members of the Chinese HCM family, which resulted a glycine (Gly) to arginine (Arg) exchange at amino acid residue 425.	Glycine	141-144	myosin heavy chain 7	Homo sapiens	65-69
21038778-1	2010	The genetic polymorphisms at the 16th (Arg--&gt; Gly) and 27th (Gln--&gt;Glu) amino acid positions of the beta2-adrenergic receptor (ADRB2) may be linked to various asthma-related phenotypes.	Glycine	49-52	adrenoceptor beta 2	Homo sapiens	106-131
20471275-2	2010	Our previous studies showed that the high-affinity HSP47-binding motif in the collagen triple helix is Xaa-(Thr/Pro)-Gly-Xaa-Arg-Gly.	Glycine	129-132	serpin family H member 1	Homo sapiens	51-56
8462540-3	1993	p50 is a basic protein (pI approximately 9.5) and is characterized by a high glycine content of approximately 20%.	Glycine	77-84	Y-box-binding protein 1	Oryctolagus cuniculus	0-3
20204449-2	2010	TBCE/yeast Pac2 comprises CAP-Gly, LRR (leucine-rich region), and UbL (ubiquitin-like) domains.	Glycine	30-33	Pac2p	Saccharomyces cerevisiae S288C	11-15
20204449-8	2010	This is suppressed by ectopic PAC2 with both the CAP-Gly and UbL domains being essential.	Glycine	53-56	Pac2p	Saccharomyces cerevisiae S288C	30-34
20642000-4	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
19176531-5	2009	Despite the trajectory of the methyl group, we observed an increase in the C20-Gly(188) (EL2) distance consistent with an increase in separation between the retinal and EL2 upon activation.	Glycine	79-82	spectrin alpha, erythrocytic 1	Homo sapiens	169-172
7679680-8	1993	The synthetic peptide Gly-Arg-Gly-Asp-Ser (GRGDS), which competes for the binding of fibronectin to its cell receptors and inhibits the adhesion of endothelial cells to substrates, arrested the elongation of developing microvessels causing regression and inhibition of angiogenesis.	Glycine	22-25	fibronectin 1	Rattus norvegicus	85-96
19441602-1	2009	BACKGROUND: Beta 2-Adrenergic receptor polymorphisms occurring at amino acid positions 16 (arginine/glycine) and 27 (glutamine/glutamic acid) are known to be functionally relevant.	Glycine	100-107	adrenoceptor beta 2	Homo sapiens	12-38
20819418-2	2010	Three mis-sense mutations of the beta-myosin heavy chain gene, MYH7, were found: valine (Val) 606 methionine (Met), arginine (Arg) 694 leucine (Leu), and Arg 723 glycine (Gly).	Glycine	171-174	myosin heavy chain 7	Homo sapiens	63-67
8430835-5	1993	In additional experiments, the effects of glycine on phospholipid changes and cell injury induced by exogenous phospholipase A2 (PLA2) were studied.	Glycine	42-49	phospholipase A2 group IB	Rattus norvegicus	111-127
19932771-6	2010	The catalytic domain of MMP-12 binds to the triple helix and cleaves the typical sites -Gly(775)-Leu(776)- in alpha-2 type I collagen and -Gly(775)-Ile(776)- in alpha-1 type I and type III collagens and at multiple other sites in both collagen types.	Glycine	88-91	matrix metallopeptidase 12	Homo sapiens	24-30
19932771-6	2010	The catalytic domain of MMP-12 binds to the triple helix and cleaves the typical sites -Gly(775)-Leu(776)- in alpha-2 type I collagen and -Gly(775)-Ile(776)- in alpha-1 type I and type III collagens and at multiple other sites in both collagen types.	Glycine	139-142	matrix metallopeptidase 12	Homo sapiens	24-30
19287951-6	2009	Similarly, BRCA1 cancer-predisposing mutation (61Cys-Gly) abrogated the ability to both bind Ubc9 as well as inhibit ERalpha activity suggesting physiological significance.	Glycine	53-56	BRCA1 DNA repair associated	Homo sapiens	11-16
19258348-6	2009	Collectively, these results showed that CSDP1 and CSDP2 perform different functions in seed germination and growth of Arabidopsis under stress conditions, and that the glycine-rich region interspersed with CCHC-type zinc fingers is particularly important for its nucleic acid-binding activities and function.	Glycine	168-175	cold shock domain protein 1	Arabidopsis thaliana	40-45
1385408-5	1992	In the disintegrin region, the Arg-Gly-Asp sequence is replaced by Glu-Cys-Asp, as found in non-Arg-Gly-Asp disintegrin regions of HR1B and a guinea pig sperm fusion protein PH-30 beta.	Glycine	35-38	disintegrin and metalloproteinase domain-containing protein 2	Cavia porcellus	174-184
19821123-5	2010	The affected positions in CK2 alpha are mainly distributed over the glycine-rich loop (G-loop), the alpha-helix and the loop located at the portion between G-loop and alpha-helix (C-loop).	Glycine	68-75	casein kinase 2 alpha 2	Homo sapiens	26-35
1426258-3	1992	Peptides Ala-783-Lys-799 and Ala-783-Arg-798 inhibited calmodulin independent MLCK at the same potency as the peptide Ala-783-Gly-804.	Glycine	126-129	myosin light chain kinase	Homo sapiens	78-82
20198471-3	2010	OBJECTIVES: In the present study, we investigated the effects of positive modulation of glycine sites on the NMDA receptor using an agonist of the glycine modulatory site, D: -serine, and a glycine transporter-1 inhibitor, (R)-(N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine (NFPS).	Glycine	88-95	solute carrier family 6 member 9	Rattus norvegicus	190-211
20198471-10	2010	CONCLUSIONS: The present results show that stimulation of the glycine modulatory sites on the NMDA receptor either directly with D: -serine or by blocking glycine transporter-1 enhances social memory and may be an effective approach for the treatment of the cognitive dysfunction observed in schizophrenic patients.	Glycine	62-69	solute carrier family 6 member 9	Rattus norvegicus	155-176
19074770-4	2009	Here, by separating the two CLIP-170 CAP-Gly domains and their adjacent serine-rich regions into fragments of varied size, we have characterized the minimal plus-end tracking unit of CLIP-170 in vivo.	Glycine	41-44	CAP-Gly domain containing linker protein 1	Homo sapiens	183-191
19199613-4	2009	In this work, we measure 2D IR spectra of a 3(10)-helical hexapeptide, Z-Aib-l-Leu-(Aib)(2)-Gly-Aib-OtBu, and its (13)C=(18)O-Leu monolabeled and (13)C=(18)O-Leu/(15)N-Gly bis-labeled isotopomers in CDCl(3).	Glycine	92-95	ANIB1	Homo sapiens	73-76
19199613-4	2009	In this work, we measure 2D IR spectra of a 3(10)-helical hexapeptide, Z-Aib-l-Leu-(Aib)(2)-Gly-Aib-OtBu, and its (13)C=(18)O-Leu monolabeled and (13)C=(18)O-Leu/(15)N-Gly bis-labeled isotopomers in CDCl(3).	Glycine	92-95	ANIB1	Homo sapiens	84-87
1356833-6	1992	NAAG-induced current in NMDAR1-injected oocytes was potentiated by glycine, dose-dependently antagonized by DL-2-amino-5-phosphonovaleric acid, and blocked by magnesium ions in a voltage-dependent fashion.	Glycine	67-74	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	24-30
19199613-4	2009	In this work, we measure 2D IR spectra of a 3(10)-helical hexapeptide, Z-Aib-l-Leu-(Aib)(2)-Gly-Aib-OtBu, and its (13)C=(18)O-Leu monolabeled and (13)C=(18)O-Leu/(15)N-Gly bis-labeled isotopomers in CDCl(3).	Glycine	92-95	ANIB1	Homo sapiens	84-87
18824844-3	2009	METHODS: Renal and systemic HGF expressions were evaluated during the development of Gly-AKI.	Glycine	85-88	hepatocyte growth factor	Rattus norvegicus	28-31
18824844-8	2009	The analysis of mRNA expressions of Th1 (t-bet, TNF-alpha, IL-1beta) and Th2 (gata-3, IL-4, IL-10) cytokines showed a Th1-polarized response in Gly-AKI rats that was aggravated with the anti-HGF treatment.	Glycine	144-147	hepatocyte growth factor	Rattus norvegicus	191-194
19019446-13	2009	All affected but none of the unaffected family members had a heterozygous missense mutation in exon 14 of the TGFBI gene (G-->A transition at nucleotide 1915) replacing glycin by aspartic acid amino acid (Gly623Asp) at position 623 of the KE protein.	Glycine	169-175	transforming growth factor beta induced	Homo sapiens	110-115
20018230-2	2010	Here we have studied such differences on motoneurons in the neonatal rat cord using ifenprodil known to inhibit voltage-, use- and glycine-independent responses mediated by NR2B-containing N-methyl-d-aspartate receptors (NMDARs) with high specificity.	Glycine	131-138	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	173-177
20231318-5	2010	Second, mutation of a conserved glycine, Gly100 in the TEN (telomerase essential N-terminal) domain of TERT, abolished the enhancement of telomerase processivity by POT1-TPP1, in contrast to other single amino acid mutations.	Glycine	32-39	tripeptidyl peptidase 1	Homo sapiens	170-174
19468822-2	2010	In plants, some amino acids work as buffers: during photorespiration, ammonium derived from the conversion of glycine to serine is promptly reassimilated into glutamate by the glutamine synthetase (GS-2)/ferredoxin-dependent glutamate synthase (Fd-GOGAT) cycle.	Glycine	110-117	glutamine synthetase 2	Arabidopsis thaliana	198-202
20008324-8	2010	Fluorescence spectroscopy and nuclear magnetic resonance studies in the presence of the cytoskeleton-associated protein-glycine-rich domains of either CLIP-170 or p150(glued) or of a fragment derived from the adenomatous polyposis coli tumor suppressor protein show that chain exchange of EBc domains can be controlled by binding partners.	Glycine	120-127	CAP-Gly domain containing linker protein 1	Homo sapiens	151-159
1334240-0	1992	A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo.	Glycine	2-9	carbonic anhydrase 1	Rattus norvegicus	46-49
19943267-4	2010	We synthesised and analysed the molecular and supramolecular structure of some polypeptides with sequences belonging to the glycine-rich repeated domain of D. melanogaster resilin.	Glycine	124-131	resilin	Drosophila melanogaster	172-179
20641678-1	2004	Both GRP and BBN share an amidated C-terminus sequence homology of 7 amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2.	Glycine	95-98	gastrin releasing peptide	Homo sapiens	5-8
1510968-1	1992	The function of a highly mobile loop in Escherichia coli dihydrofolate reductase was studied by constructing a mutant (DL1) using cassette mutagenesis that had four residues deleted in the middle section of the loop (Met16-Ala19) and a glycine inserted to seal the gap.	Glycine	236-243	Dihydrofolate reductase	Escherichia coli	57-80
19159593-4	2008	RESULTS: Mutation G14452A was identified in exon 22 of MYH7 gene in 4 family members, causing the conversion of glycine (G) into glutamic acid (E).	Glycine	112-119	myosin heavy chain 7	Homo sapiens	55-59
19850376-2	2010	A comparison of several crystal structures of MK2 shows that differences in active and inactive conformations result in large part from structural variations within the conformations of the glycine rich loop (p-loop) regions.	Glycine	190-197	MAPK activated protein kinase 2	Homo sapiens	46-49
20641262-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
20641458-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
1386601-5	1992	The NH2-terminal glycine of each retinal recoverin molecule is linked to one of four different types of acyl groups.	Glycine	17-24	recoverin	Bos taurus	41-50
20641743-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
19179765-3	2008	A critical weak link is created in glycine biosynthesis by the stoichiometry of the reaction catalyzed by glycine hydroxymethyltransferase (EC 2.1.2.1), which converts serine into glycine plus one C1 unit: this produces an absolute dependence of the glycine production flux on the utilization of C1 units for other metabolic pathways that do not work coordinately with glycine use.	Glycine	35-42	serine hydroxymethyltransferase 2	Homo sapiens	106-138
20641917-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
1378072-5	1992	Binding to fibronectin was blocked by a synthetic peptide containing the sequence Arg-Gly-Asp.	Glycine	86-89	fibronectin 1	Rattus norvegicus	11-22
19719118-1	2009	Integrin alpha(v)beta(3) plays a significant role in tumor angiogenesis and is a receptor for the extracellular matrix proteins with the exposed arginine-glycine-aspartic (RGD) tripeptide sequence.	Glycine	154-161	integrin subunit alpha V	Homo sapiens	0-24
18796308-0	2008	A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral-CA1 synapses in hippocampus.	Glycine	16-23	carbonic anhydrase 1	Homo sapiens	122-125
1457864-4	1992	RGD ALB was prepared via a coupling reaction of albumin with pentapeptide (GRGDS; Gly-RGD-Ser) by water soluble carbodiimide.	Glycine	82-85	albumin	Bos taurus	4-7
18536011-5	2008	The theoretical results on the absolute binding-free energies for leucine, alanine, and glycine show that alanine can be a potent substrate for LeuT, although leucine is preferred, which is consistent with the recent experimental data (Singh et al., Nature 2007;448:952-956).	Glycine	88-95	Leucine transport, high	Homo sapiens	144-148
18536011-6	2008	Furthermore, LeuT displays robust specificity for leucine over glycine.	Glycine	63-70	Leucine transport, high	Homo sapiens	13-17
18536011-9	2008	The introduction of a polar ligand such as glycine to the water-depleted binding pocket of LeuT gives rise to structural rearrangements of the R30-D404-Q250 hydrogen-bonding network and leads to increased hydration of the binding pocket.	Glycine	43-50	Leucine transport, high	Homo sapiens	91-95
19806166-6	2009	The par2-1 mutant carries a missense mutation in a highly conserved glycine, which renders the mutant protein unstable.	Glycine	68-75	phy rapidly regulated 2	Arabidopsis thaliana	4-8
1387804-3	1992	Among several differences in the active site region the most significant appears to be the replacement of Ser11 in MPGM by Gly in BPGM.	Glycine	123-126	bisphosphoglycerate mutase	Homo sapiens	130-134
18601653-7	2008	Taken together these results indicate that two consecutive segments including two Group-1 epitopes, Leu(191) and Gln(194), comprise an interface between CD151 and integrin alpha 3 beta 1, and, along with the epitope including Gly(176)/Gly(177), are concealed by bound integrin.	Glycine	226-229	CD151 molecule (Raph blood group)	Homo sapiens	153-158
18601653-7	2008	Taken together these results indicate that two consecutive segments including two Group-1 epitopes, Leu(191) and Gln(194), comprise an interface between CD151 and integrin alpha 3 beta 1, and, along with the epitope including Gly(176)/Gly(177), are concealed by bound integrin.	Glycine	226-229	integrin subunit alpha 3	Homo sapiens	163-179
1283100-6	1992	IGFBP-3 and -4 are glycosylated, whereas IGFBP-1 and -2 contain an Arg-Gly-Asp sequence near the carboxyl terminus.	Glycine	71-74	insulin like growth factor binding protein 1	Homo sapiens	41-55
18601653-7	2008	Taken together these results indicate that two consecutive segments including two Group-1 epitopes, Leu(191) and Gln(194), comprise an interface between CD151 and integrin alpha 3 beta 1, and, along with the epitope including Gly(176)/Gly(177), are concealed by bound integrin.	Glycine	235-238	CD151 molecule (Raph blood group)	Homo sapiens	153-158
18601653-7	2008	Taken together these results indicate that two consecutive segments including two Group-1 epitopes, Leu(191) and Gln(194), comprise an interface between CD151 and integrin alpha 3 beta 1, and, along with the epitope including Gly(176)/Gly(177), are concealed by bound integrin.	Glycine	235-238	integrin subunit alpha 3	Homo sapiens	163-179
18836295-7	2008	Recently, some studies indicated that coupling special ligand like NGR (N: asparagine, G: glycine, R: arginine) peptide targeting to tumor blood vessels with delivery system can enhance the efficacy of gene transfection.	Glycine	90-97	reticulon 4 receptor	Homo sapiens	67-70
1637501-3	1992	A complete three-dimensional structure for the ras-gene-encoded p21 protein with Gly 12 and Gln 61, bound to GDP, has been constructed in four stages using the available alpha-carbon coordinates as deposited in the Brookhaven National Laboratories Protein Data Bank.	Glycine	81-84	H3 histone pseudogene 16	Homo sapiens	64-67
1593644-2	1992	The alignment shows that only 9 amino acid residues (of 374 in the horse liver ADH sequence) are conserved in this family; these include eight Gly and one Val with structural roles.	Glycine	143-146	alcohol dehydrogenase 1A (class I), alpha polypeptide	Homo sapiens	79-82
18708347-7	2008	NMR heteronuclear single quantum coherence titrations revealed that upon binding, both molecules significantly perturb EphA4 residues Ile(31)-Met(32) in the D-E loop, Gln(43) in the E beta-strand, and Ile(131)-Gly(132) in the J-K loop.	Glycine	210-213	EPH receptor A4	Homo sapiens	119-124
1349575-0	1992	A glycine-to-glutamate substitution abolishes alanine:glyoxylate aminotransferase catalytic activity in a subset of patients with primary hyperoxaluria type 1.	Glycine	2-9	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	46-81
18644786-2	2008	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible and THF-dependent conversion of serine to glycine and 5,10-methylene-THF.	Glycine	106-113	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	0-31
18644786-2	2008	Serine hydroxymethyltransferase (SHMT) catalyzes the reversible and THF-dependent conversion of serine to glycine and 5,10-methylene-THF.	Glycine	106-113	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	33-37
18700728-6	2008	Using a focused peptide library based on a sequence derived from the in vivo substrate fibrillarin we observed that PRMT1 methylated substrates that had amino acid residues other than glycine in the "RX (1)" and "RX (1)X (2)" positions.	Glycine	184-191	protein arginine methyltransferase 1	Homo sapiens	116-121
1353910-4	1992	In this report we show that a G-to-A transition in the first position of codon 717 of the EF-2 gene results in substitution of arginine for glycine and prevents addition of the side chain of diphthamide to histidine 715 of EF-2.	Glycine	140-147	eukaryotic translation elongation factor 2	Homo sapiens	90-94
18523967-2	2008	The thioxo analog Phe(1)-Tyr(2)-psi[CS-N]-Pro(3)-Trp(4)-Gly(5)-NH(2) (psi[CS-N](2)-kinin), was synthesized by Fmoc solid-phase peptide strategy.	Glycine	56-59	transient receptor potential cation channel subfamily C member 4	Homo sapiens	49-54
1353910-4	1992	In this report we show that a G-to-A transition in the first position of codon 717 of the EF-2 gene results in substitution of arginine for glycine and prevents addition of the side chain of diphthamide to histidine 715 of EF-2.	Glycine	140-147	eukaryotic translation elongation factor 2	Homo sapiens	223-227
1525950-3	1992	An insulin derivative which has a group at the Lys(B29)-position is prepared by the S-acetylthioglycoloylation of Gly(A1), Phe(B1)-dicitraconyl insulin followed by decitraconylation.	Glycine	114-117	CD79b molecule	Homo sapiens	47-54
18554750-3	2008	The mutant, called long bone abnormality (lbab), contains a single point mutation that converts an arginine to a glycine in a conserved coding region of the CNP gene, but how this mutation affects CNP activity has not been reported.	Glycine	113-120	natriuretic peptide type C	Mus musculus	157-160
18621031-1	2008	The actions of neurotransmitter glycine are regulated by the Na+/Cl(-) dependent high-affinity glycine transporters, GlyT1 and GlyT2.	Glycine	32-39	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	127-132
1312542-8	1992	However, a mutation was identified in codon 12 of the H-ras gene (Gly to Val) in a recurrent prolactinoma that was highly invasive and ultimately proved to be fatal.	Glycine	66-69	HRas proto-oncogene, GTPase	Homo sapiens	54-59
18577424-3	2008	KCC2 is a neuron-specific potassium chloride cotransporter whose role in mature central neurons is to maintain the low intracellular Cl(-) concentrations required for the hyperpolarizing responses to the inhibitory amino acids GABA and glycine.	Glycine	236-243	solute carrier family 12 member 5	Homo sapiens	0-4
18852529-2	2008	In vitro, glycine reduces tumor necrosis factor (TNF)-alpha secretion and increases interleukin-10 secretion in human monocytes stimulated with lipopolysaccharide.	Glycine	10-17	interleukin 10	Homo sapiens	84-98
1532227-1	1992	Serine hydroxymethyltransferase (SHMT) occupies a central position in one-carbon (C1) metabolism, catalyzing the reaction of serine and tetrahydrofolate to yield glycine and 5,10-methylenetetrahydrofolate.	Glycine	162-169	serine hydroxymethyltransferase 1	Homo sapiens	33-37
1372711-4	1992	Here we describe a "complementary" mutation at the other end of the other keratin expressed by these cells (K5, coexpressed with K14), a change from a Glu to a Gly in the helix termination peptide, detected by altered antibody binding and confirmed by sequencing using the polymerase chain reaction.	Glycine	160-163	keratin 14	Homo sapiens	129-132
18756100-4	2008	Unexpectedly, mutant H-16 (Gly-Leu-Val-Tyr) showed almost identical hydrolyzing and transglycosylation activities to wild type, whereas K-33 (Ser-Gly-Asp-Glu) showed an extremely low transglycosylation activity.	Glycine	27-30	H1.6 linker histone, cluster member	Homo sapiens	21-25
1537377-0	1992	Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen.	Glycine	62-65	endoglin	Homo sapiens	45-53
18558993-3	2008	Dominant dystrophic epidermolysis bullosa usually involves glycine substitutions within the triple helix of COL7A1 although other missense mutations, deletions or splice-site mutations may underlie some cases.	Glycine	59-66	collagen type VII alpha 1 chain	Homo sapiens	108-114
1811271-0	1991	Glycine-extended gastrin precursors.	Glycine	0-7	gastrin	Homo sapiens	17-24
18714823-5	2008	beta2-AR genotypes and allele frequencies at amino acid positions 16 (beta2-AR-16: Arg--&gt;Gly) and 27 (beta2-AR-27: Gln--&gt;Glu) were identified by PCR-RFLP.	Glycine	92-95	adrenoceptor beta 2	Homo sapiens	0-8
1896454-2	1991	VLA-4 binds to the peptide sequence Gly-Pro-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr (GPEILDVPST in single-letter code) on the alternatively spliced CS-1 form of FN, whereas VLA-5 binds to an Arg-Gly-Asp sequence found on all forms of FN.	Glycine	36-39	integrin alpha 5 (fibronectin receptor alpha)	Mus musculus	165-170
1896454-2	1991	VLA-4 binds to the peptide sequence Gly-Pro-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr (GPEILDVPST in single-letter code) on the alternatively spliced CS-1 form of FN, whereas VLA-5 binds to an Arg-Gly-Asp sequence found on all forms of FN.	Glycine	36-39	fibronectin 1	Mus musculus	153-155
1788145-3	1991	This sequence differs from that of pig neuromedin U-8 (NMU-8) by the substitution of Leu3 by Phe and, like the corresponding peptide from the guinea pig, is extended from the NH2-terminus by a Gly residue.	Glycine	193-196	neuromedin U	Gallus gallus	39-51
18982557-11	2008	CONCLUSION: Glycine can inhibit apoptosis in cardiomyocytes subjected to ischemia and hypoxia,and the effect may be attributable to changes in mitochondrial membrane potential, lessening opening of mPTP, alleviation of calcium overload , and decrease in activity of caspase-3.	Glycine	12-19	caspase 3	Mus musculus	266-275
18475188-10	2008	RESULTS: Compared with vehicle controls, glycine-treated graft muscularis expressed a significant alleviation in mRNA peak expression for IL-6, IL-1beta, ICAM-1, MCP-1, TNFalpha, COX-2, and iNOS.	Glycine	41-48	intercellular adhesion molecule 1	Rattus norvegicus	154-160
1654808-2	1991	The most potent of the series, CH3CH2CH2(R,S)CH(COOH)-NH-Leu-Phe-Ala-NH2, competitively inhibited cleavage of dinitrophenyl-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 at the Gly-Leu bond by MMP-1 and MMP-2 (KI = 30 and 40 microM, respectively).	Glycine	132-135	interstitial collagenase	Sus scrofa	181-186
20055845-5	2009	Molecular screening of the COL7A1 gene showed a novel heterozygous glycine substitution in type VII collagen, designated p.G2290A, in keeping with dominant dystrophic EB.	Glycine	67-74	collagen type VII alpha 1 chain	Homo sapiens	27-33
20093739-1	2009	In a previous paper, we pointed out that the capability to synthesize glycine from serine is constrained by the stoichiometry of the glycine hydroxymethyltransferase reaction, which limits the amount of glycine produced to be no more than equimolar with the amount of C 1 units produced.	Glycine	70-77	serine hydroxymethyltransferase 2	Homo sapiens	133-165
1654808-2	1991	The most potent of the series, CH3CH2CH2(R,S)CH(COOH)-NH-Leu-Phe-Ala-NH2, competitively inhibited cleavage of dinitrophenyl-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 at the Gly-Leu bond by MMP-1 and MMP-2 (KI = 30 and 40 microM, respectively).	Glycine	132-135	matrix metallopeptidase 2	Sus scrofa	191-196
19666071-5	2009	These uptake studies suggest that GlyT1 and system A are involved in [(14)C]glycine uptake by TR-iBRB2 cells.	Glycine	76-83	solute carrier family 6 member 9	Rattus norvegicus	34-39
19666071-8	2009	In conclusion, GlyT1 most likely mediates glycine transport at the inner BRB and is expected to play an important role in regulating the glycine concentration in the neural retina.	Glycine	42-49	solute carrier family 6 member 9	Rattus norvegicus	15-20
17983645-2	2008	The plasma membrane receptor is located on integrin alphaVbeta3 at the Arg-Gly-Asp recognition site important to the binding by the integrin of extracellular matrix proteins.	Glycine	75-78	integrin subunit alpha V	Homo sapiens	43-63
2010533-6	1991	Amino acid sequence comparisons of the region surrounding glycine-142 indicated that it is highly conserved among lipases from different species, suggesting a crucial role of this domain for the LPL structure.	Glycine	58-65	lipoprotein lipase	Homo sapiens	195-198
18243325-2	2008	The fourth transmembrane domain (TM4) housing the disease-causing mutations both in Nramp1 and Nramp2 at the conserved two adjacent glycine residues, was implicated to serve an important biological function.	Glycine	132-139	solute carrier family 11 member 1	Rattus norvegicus	84-90
18222923-1	2008	The familial cylindromatosis tumor suppressor CYLD is known to contain three cytoskeleton-associated protein glycine-rich (CAP-Gly) domains, which exist in a number of microtubule-binding proteins and are responsible for their association with microtubules.	Glycine	109-116	CYLD lysine 63 deubiquitinase	Homo sapiens	46-50
18222923-1	2008	The familial cylindromatosis tumor suppressor CYLD is known to contain three cytoskeleton-associated protein glycine-rich (CAP-Gly) domains, which exist in a number of microtubule-binding proteins and are responsible for their association with microtubules.	Glycine	127-130	CYLD lysine 63 deubiquitinase	Homo sapiens	46-50
18222923-3	2008	In this study, our data demonstrate that CYLD associates with microtubules both in cells and in vitro, and the first CAP-Gly domain of CYLD is mainly responsible for the interaction.	Glycine	121-124	CYLD lysine 63 deubiquitinase	Homo sapiens	41-45
18222923-3	2008	In this study, our data demonstrate that CYLD associates with microtubules both in cells and in vitro, and the first CAP-Gly domain of CYLD is mainly responsible for the interaction.	Glycine	121-124	CYLD lysine 63 deubiquitinase	Homo sapiens	135-139
19666071-8	2009	In conclusion, GlyT1 most likely mediates glycine transport at the inner BRB and is expected to play an important role in regulating the glycine concentration in the neural retina.	Glycine	137-144	solute carrier family 6 member 9	Rattus norvegicus	15-20
19715676-1	2009	Structural data suggests that bulky hydrophobic residues at the S2-S4 sub-sites of factor Xa (fXa) restrict the preference of this pocket for small and non-polar residues like Gly at the P2 position of substrates and inhibitors.	Glycine	176-179	coagulation factor X	Homo sapiens	83-92
19715676-1	2009	Structural data suggests that bulky hydrophobic residues at the S2-S4 sub-sites of factor Xa (fXa) restrict the preference of this pocket for small and non-polar residues like Gly at the P2 position of substrates and inhibitors.	Glycine	176-179	coagulation factor X	Homo sapiens	94-97
19715676-5	2009	Substitution of Tyr-99 of fXa with a Gly dramatically impaired the reactivity of fXa with wild-type AT, but improved its reactivity with the serpin mutants in the absence, but not in the presence of pentasaccharide.	Glycine	37-40	coagulation factor X	Homo sapiens	81-84
18222923-6	2008	In addition, we have identified by wound healing assay a critical role for CYLD in mediating cell migration and found that its first CAP-Gly domain is required for this activity.	Glycine	137-140	CYLD lysine 63 deubiquitinase	Homo sapiens	75-79
2051722-6	1991	The action of glycine was not reduced by the addition of a substrate (benzoate) or a product (hippurate) of the glycine N-acyltransferase reaction.	Glycine	14-21	glycine-N-acyltransferase	Rattus norvegicus	112-137
19863667-5	2009	BmHrp28 has two RNA recognition motifs at the N-terminal and a glycine-rich motif at the C-terminal.	Glycine	63-70	hnRNPA/B-like 28	Bombyx mori	0-7
1658758-2	1991	Synthesis of four new derivatives of enkephalin analogs: H-BuTyr-DMet-Gly- Phe-epsilon Ahx-OH 9, H-BzlTyr-DMet-Gly-Phe-epsilon Ahx-OH 12, H-Butyr-DMet-Gly- -Phe-epsilon Ahx-epsilon Ahx-OH 15 and H-BzlTyr-DMet-Gly-Phe-epsilon Ahx-OH is reported.	Glycine	70-73	proenkephalin	Rattus norvegicus	37-47
18324973-4	2008	We found that the beta(2)AR arg(16)--&gt;gly substitution and two non-coding ADCY6 polymorphisms were associated with elevated adhesion.	Glycine	41-44	adrenoceptor beta 2	Homo sapiens	18-27
18262473-2	2008	Elements of the glycinergic phenotype include the membrane-bound glycine transporters (GLYT1 and GLYT2), which remove glycine from the synaptic cleft, and the vesicular inhibitory amino acid transporter (VIAAT or VGAT), which sequesters both glycine and GABA into synaptic vesicles.	Glycine	65-72	solute carrier family 6 member 5 S homeolog	Xenopus laevis	97-102
19948790-5	2009	Mutation of either Leu-487 or Pro-488 to an Ala improves catalytic efficiency using Gly, but a double mutation (L487A/P488A) is required to convert the substrate preference of hGS from beta-Ala to Gly.	Glycine	84-87	hepatocyte growth factor-regulated tyrosine kinase substrate	Homo sapiens	176-179
1996985-0	1991	Structural and expression analyses of normal and mutant mRNA encoding glycine decarboxylase: three-base deletion in mRNA causes nonketotic hyperglycinemia.	Glycine	70-77	aminomethyltransferase	Homo sapiens	128-154
19948790-5	2009	Mutation of either Leu-487 or Pro-488 to an Ala improves catalytic efficiency using Gly, but a double mutation (L487A/P488A) is required to convert the substrate preference of hGS from beta-Ala to Gly.	Glycine	197-200	hepatocyte growth factor-regulated tyrosine kinase substrate	Homo sapiens	176-179
19726672-1	2009	Dominant-negative interference by glycine substitution mutations in the COL7A1 gene causes dominant dystrophic epidermolysis bullosa (DDEB), a skin fragility disorder with mechanically induced blistering.	Glycine	34-41	collagen type VII alpha 1 chain	Homo sapiens	72-78
18270170-8	2008	Na(V)1.4 channels with one CaM fused to the CT by variable length glycine linkers exhibit CaM modulation of gating only with linker lengths that allowed CaM to reach IQ region.	Glycine	66-73	immunoglobulin lambda variable 2-14	Homo sapiens	0-8
17980459-2	2008	Extracellular levels of glycine are primarily regulated by the plasma membrane glycine transporter 1.	Glycine	24-31	solute carrier family 6 member 9	Rattus norvegicus	79-100
20641508-4	2004	GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2) which is necessary for receptor binding and signal transduction (56).	Glycine	62-65	gastrin releasing peptide	Homo sapiens	0-3
1824011-1	1991	The main objective of this work was to use positive-ion fast atom bombardment mass spectrometry (FAB-MS) B/E linked scan spectra to investigate the possibility of differentiating positional isomers of various authentic glycine- and taurine-conjugated bile acids.	Glycine	219-226	FA complementation group B	Homo sapiens	97-100
20641903-4	2004	GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2), which is necessary for receptor binding and signal transduction (5, 6).	Glycine	62-65	gastrin releasing peptide	Homo sapiens	0-3
20641937-4	2004	GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2), which is necessary for receptor binding and signal transduction (5, 6).	Glycine	62-65	gastrin releasing peptide	Homo sapiens	0-3
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	106-109
19596784-2	2009	TRF2 contains an N-terminal basic domain rich in glycines and arginines, similar to the GAR motif that is methylated by protein arginine methyltransferases.	Glycine	49-57	telomeric repeat binding factor 2	Homo sapiens	0-4
18709962-7	2008	Bi-directional sequencing of exon 3 showed a single base-pair substitution, which results in an amino acid substitution at position83, glycine to arginine (TTR Arg-83).	Glycine	135-142	transthyretin	Homo sapiens	156-159
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
17919119-1	2008	The GLYT1 (glycine transporter-1) regulates both glycinergic and glutamatergic neurotransmission by controlling the reuptake of glycine at synapses.	Glycine	11-18	solute carrier family 6 member 9	Rattus norvegicus	4-9
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
17657484-4	2008	We investigated the role of these two positions in heteromeric Kir4.1/Kir5.1 channels, which are unique amongst Kir channels in that both subunits lack a conserved glycine at the upper hinge position.	Glycine	164-171	potassium inwardly rectifying channel subfamily J member 16	Homo sapiens	70-76
19577562-1	2009	The laminin tyrosine-isoleucine-glycine-serine-arginine (YIGSR) peptide, corresponding to the 929-933 sequence of beta1 chain, is known to inhibit tumor growth and metastasis.	Glycine	32-39	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	114-119
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	106-109
18245597-2	2008	The disorder is caused by a recurrent missense mutation in the glycine-serine activation domain of activin A receptor type I, a bone morphogenetic protein (BMP) type-I receptor, in all classically affected individuals.	Glycine	63-70	activin A receptor type 1	Homo sapiens	99-124
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
19549823-1	2009	Alanyl-tRNA synthetase (AlaRS) catalyzes synthesis of Ala-tRNA(Ala) and hydrolysis of mis-acylated Ser- and Gly-tRNA(Ala) at 2 different catalytic sites.	Glycine	108-111	alanyl-tRNA synthetase 1	Homo sapiens	0-22
1652268-6	1991	When ras proteins were preactivated with the non-hydrolysable GTP analog GppNHp, the time courses of both p21(Gly-12) and p21(Val-12) effects were fast and sustained, suggesting that in intact cells (i) the GDP/GTP exchange is faster for p21(Gly-12) compared to p21(Val-12) and (ii) inactivation of p21(Gly-12) is mediated by GAP-induced GTPase activity.	Glycine	242-245	H3 histone pseudogene 16	Homo sapiens	122-125
19549823-1	2009	Alanyl-tRNA synthetase (AlaRS) catalyzes synthesis of Ala-tRNA(Ala) and hydrolysis of mis-acylated Ser- and Gly-tRNA(Ala) at 2 different catalytic sites.	Glycine	108-111	alanyl-tRNA synthetase 1	Homo sapiens	24-29
18247304-5	2008	The frequency of Gly allele at the Arg16Gly locus in beta2-adrenergic receptor gene in the population (0.446) was similar to that of Japanese (0.505), higher than that of American white(0.248), and lower than that of Polish population (0.633).	Glycine	17-20	adrenoceptor beta 2	Homo sapiens	53-78
1685408-2	1991	A soluble human brain aminopeptidase which hydrolyses the Tyr-Gly bond of Met-enkephalin and Leu-enkephalin was identified in the brains of the following vertebrates: mammals (Callithrix jacchus and Rattus norvegicus), bird (Gallus domesticus), reptile (Tupinambis teguixin), amphibia (Bufo paracnemis), fish (Sarotherdon niloticus) and elasmobranchy (Galeocerdo cuvieri).	Glycine	62-65	prodynorphin	Homo sapiens	93-107
19401151-2	2009	sL1 is a ligand for several Arg-Gly-Asp (RGD)-binding integrins and can be deposited in the extracellular matrix.	Glycine	32-35	TATA-box binding protein associated factor, RNA polymerase I subunit A	Homo sapiens	0-3
2014216-11	1991	Leu-D(Ala)2-enkephalin, while showing enhanced stability against aminopeptidase hydrolysis, is hydrolyzed at the Gly-Phe bond by the endopeptidase.	Glycine	113-116	proenkephalin	Rattus norvegicus	12-22
19393690-6	2009	Glycine transporter (GlyT) 1 and GlyT2, which are located in glial cells and neurons, respectively play important roles by clearing synaptically released glycine or supplying glycine to glycinergic neurons to regulate glycinergic neurotransmission.	Glycine	154-161	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	33-38
19393690-6	2009	Glycine transporter (GlyT) 1 and GlyT2, which are located in glial cells and neurons, respectively play important roles by clearing synaptically released glycine or supplying glycine to glycinergic neurons to regulate glycinergic neurotransmission.	Glycine	175-182	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	33-38
19395377-7	2009	IaI heavy chains contain von Willebrand A domains that can bind the arginine-glycine-aspartate domain of vitronectin.	Glycine	77-84	vitronectin	Mus musculus	105-116
18221556-3	2008	Two divergent copies of the ribosomal protein S13 gene (rps13) of chloroplast origin are found in the nucleus of the rosids Arabidopsis, Gossypium, and Glycine.	Glycine	152-159	ribosomal protein S13	Malus domestica	56-61
18215303-8	2008	Two frameshifts, in the cox3 and nad6 genes, were not corrected by RNA editing, but rather possessed identical shift sites marked by the extremely rare tryptophan codon (UGG) followed by the common glycine codon (GGA) in the +1 frame.	Glycine	198-205	COX3	Aphrocallistes vastus	24-28
19395377-9	2009	We show that IaI binds vitronectin at the arginine-glycine-aspartate site, thereby promoting epithelial adhesion and migration in vitro.	Glycine	51-58	vitronectin	Mus musculus	23-34
2249628-1	1990	Peptidylglycine alpha-amidating monooxygenase (PAM; EC 1.14.17.3) is a granule-associated enzyme that catalyzes the production of alpha-amidated peptides from their glycine-extended precursors, a posttranslational modification often required for full biological activity.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	47-50
19159928-6	2009	RESULTS: The new RGD dimers with the Gly(3) and PEG(4) linkers showed higher integrin alpha(v)beta(3) binding affinity than no-linker RGD dimer (RGD2).	Glycine	37-40	integrin subunit alpha V	Homo sapiens	77-100
20641649-0	2004	Gly-Ser-Ser-Lys-(FITC)-Gly-Gly-Gly-Cys-Arg-Gly-Asp-Cys-CLIO-Cy5.5 The alphaupsilonbeta3 integrin, also known as the vitronectin receptor, is a heterodimeric transmembrane glycoprotein found on most cells originating from mesenchyme (1).	Glycine	0-3	vitronectin	Homo sapiens	116-127
20641649-0	2004	Gly-Ser-Ser-Lys-(FITC)-Gly-Gly-Gly-Cys-Arg-Gly-Asp-Cys-CLIO-Cy5.5 The alphaupsilonbeta3 integrin, also known as the vitronectin receptor, is a heterodimeric transmembrane glycoprotein found on most cells originating from mesenchyme (1).	Glycine	23-26	vitronectin	Homo sapiens	116-127
20641649-0	2004	Gly-Ser-Ser-Lys-(FITC)-Gly-Gly-Gly-Cys-Arg-Gly-Asp-Cys-CLIO-Cy5.5 The alphaupsilonbeta3 integrin, also known as the vitronectin receptor, is a heterodimeric transmembrane glycoprotein found on most cells originating from mesenchyme (1).	Glycine	23-26	vitronectin	Homo sapiens	116-127
2174257-0	1990	Electrochemical, kinetic, and circular dichroic consequences of mutations at position 82 of yeast iso-1-cytochrome c. Replacement of Phe-82 in yeast iso-1-cytochrome c with Tyr, Leu, Ile, Ser, Ala, and Gly produces a gradation of effects on (1) the reduction potential of the protein, (2) the rate of reaction with Fe(EDTA)2-, and (3) the CD spectra of the ferricytochromes in the Soret region under conditions where contributions from the alkaline forms of these proteins are absent.	Glycine	202-205	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	149-154
17949820-8	2008	No or a reduced KCC2 expression leads to a depolarizing (excitatory) action of GABA and glycine.	Glycine	88-95	solute carrier family 12 member 5	Homo sapiens	16-20
19447968-10	2009	In custard cream containing an insufficient amount of gassericin A (49 arbitrary units/mL), the gram-positive strains gradually grew but were completely inhibited by the addition of 0.5% (wt/wt) glycine.	Glycine	195-202	gaaA	Lactobacillus gasseri	54-66
18003876-6	2008	Cultured NR3A Tg neurons exhibited two populations of NMDA receptor (NMDAR) channels, reduced Mg(2+) sensitivity, and decreased Ca(2+) permeability in response to NMDA/glycine, but glycine alone did not elicit excitatory currents.	Glycine	168-175	glutamate receptor ionotropic, NMDA3A	Mus musculus	9-13
2205476-5	1990	The size of the digested product was consistent with a cleavage of pro-NPY resulting in an immunoreactive species, NPY-Gly-Lys.	Glycine	119-122	neuropeptide Y	Homo sapiens	71-74
18003876-6	2008	Cultured NR3A Tg neurons exhibited two populations of NMDA receptor (NMDAR) channels, reduced Mg(2+) sensitivity, and decreased Ca(2+) permeability in response to NMDA/glycine, but glycine alone did not elicit excitatory currents.	Glycine	181-188	glutamate receptor ionotropic, NMDA3A	Mus musculus	9-13
17999653-2	2008	DQB1*0632 differs from DQB1*0603 by one nucleotide change in exon 2 resulting in the amino acid exchange Gly --&gt; Arg.	Glycine	105-108	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	0-4
17999653-2	2008	DQB1*0632 differs from DQB1*0603 by one nucleotide change in exon 2 resulting in the amino acid exchange Gly --&gt; Arg.	Glycine	105-108	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	23-27
2205476-5	1990	The size of the digested product was consistent with a cleavage of pro-NPY resulting in an immunoreactive species, NPY-Gly-Lys.	Glycine	119-122	neuropeptide Y	Homo sapiens	115-118
1981255-1	1990	Effects of glycine were investigated in Schaffer/commissural-CA1 pyramidal cell synapses of the rat hippocampal slices.	Glycine	11-18	carbonic anhydrase 1	Rattus norvegicus	61-64
18959186-8	2008	MAP4 application has been shown to increase the glycine-mediated mlPSPs frequency more than GABA-mediated mlPSPs frequency: in average by 97.6 +/- 20.7% (n = 7) and 54.6 +/- 20.8% (n = 5), respectively.	Glycine	48-55	microtubule associated protein 4	Homo sapiens	0-4
2279848-1	1990	The GTP-binding p21 protein, encoded by the ras-oncogene, becomes transforming if amino acid substitutions are made at critical positions in the polypeptide chain, e.g., at Gly 12, Gly 13, Ala 59, Gln 61 and Glu 63.	Glycine	173-176	H3 histone pseudogene 16	Homo sapiens	16-19
17880945-3	2007	In vitro incubation of gill filaments with SS-14 or various SS isoforms, including SS-28 and [Tyr(7), Gly(10)]-SS-14-containing peptides, directly inhibited IGF-I receptor mRNA expression.	Glycine	102-105	insulin-like growth factor I	Oncorhynchus mykiss	157-162
20641723-5	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Mus musculus	31-42
2279848-1	1990	The GTP-binding p21 protein, encoded by the ras-oncogene, becomes transforming if amino acid substitutions are made at critical positions in the polypeptide chain, e.g., at Gly 12, Gly 13, Ala 59, Gln 61 and Glu 63.	Glycine	181-184	H3 histone pseudogene 16	Homo sapiens	16-19
2395872-4	1990	Sequence analysis of the isolated secretin precursor revealed a 71-amino acid residue polypeptide that contained the sequence of secretin N terminally, followed by a Gly-Lys-Arg sequence and a C-terminal extension of 41-amino acid residues.	Glycine	166-169	secretin	Sus scrofa	34-42
20641847-5	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Mus musculus	31-42
2218398-4	1990	Gastrin-17 was the main bioactive product, but its immediate precursor, glycine-extended gastrin-17, constituted the predominant part of the preprogastrin product in pancreatic tissue.	Glycine	72-79	gastrin	Homo sapiens	89-96
17660250-9	2007	Interestingly, the Gly mutant has a Ki of 2.1 nM for MMP-9 and &gt;40 muM for MMP-2, indicating that engineered TIMPs can discriminate between MMPs in the same subfamily.	Glycine	19-22	matrix metallopeptidase 9	Homo sapiens	53-58
17569661-0	2007	Essential, completely conserved glycine residue in the domain III S2-S3 linker of voltage-gated calcium channel alpha1 subunits in yeast and mammals.	Glycine	32-39	transcriptional co-activator mating type protein alpha	Saccharomyces cerevisiae S288C	112-118
2218398-4	1990	Gastrin-17 was the main bioactive product, but its immediate precursor, glycine-extended gastrin-17, constituted the predominant part of the preprogastrin product in pancreatic tissue.	Glycine	72-79	gastrin	Homo sapiens	141-154
17569661-4	2007	Comparison of amino acid sequences of this linker among 58 VGCC alpha1 subunits from 17 species reveals that a Gly residue whose position corresponds to that of the Cch1 Gly1265 is completely conserved from yeasts to humans.	Glycine	111-114	transcriptional co-activator mating type protein alpha	Saccharomyces cerevisiae S288C	64-70
2119367-1	1990	We have investigated the anti-metastatic and anti-invasive activities of polypeptide analogues based on the Arg-Gly-Asp (RGD) adhesive signal in fibronectin, poly(RGD), poly(RGDS)[Arg-Gly-Asp-Ser] and poly(RGDT)[Arg-Gly-Asp-Thr].	Glycine	112-115	fibronectin 1	Mus musculus	145-156
17569661-4	2007	Comparison of amino acid sequences of this linker among 58 VGCC alpha1 subunits from 17 species reveals that a Gly residue whose position corresponds to that of the Cch1 Gly1265 is completely conserved from yeasts to humans.	Glycine	111-114	Cch1p	Saccharomyces cerevisiae S288C	165-169
17672455-4	2007	The template sequence was based on the alpha1(V)436-450 collagen region, which is hydrolyzed at the Gly(439)-Val(440) bond selectively by MMP-2 and MMP-9.	Glycine	100-103	matrix metallopeptidase 9	Homo sapiens	148-153
17502428-7	2007	The NMDA receptor glycine site agonist, d-serine, partially activated NR1/NR3A/NR3B receptors, whereas the antagonist, 5,7-dichloro-kynurenic acid, inhibited receptor currents.	Glycine	18-25	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	79-83
2359524-0	1990	Glycine antagonists block the induction of long-term potentiation in CA1 of rat hippocampal slices.	Glycine	0-7	carbonic anhydrase 1	Rattus norvegicus	69-72
17646648-5	2007	Ala-326 is located in the I-helix, close to the terminus of the docked 25-hydroxylated side chain in a CYP24A1 homology model, a result that we interpret indicates that substitution of a glycine at 326 provides extra space for the side chain of the substrate to move deeper into the pocket and place it in a optimal stereochemical position for 23-hydroxylation.	Glycine	187-194	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	103-110
2359524-4	1990	These results indicate that glycine is a necessary factor for the induction of LTP in CA1 of the rat hippocampus.	Glycine	28-35	carbonic anhydrase 1	Rattus norvegicus	86-89
2179417-9	1990	In one SCC, a point mutation was detected at codon 12 of the K-ras gene, involving a glycine to cysteine substitution in the gene product.	Glycine	85-92	serpin family B member 3	Homo sapiens	7-10
17332249-3	2007	The other three patients with NRAS or KRAS2 glycine to serine substitution received no chemotherapy, but hematologic improvement has been observed during a 2- to 4-year follow up.	Glycine	44-51	KRAS proto-oncogene, GTPase	Homo sapiens	38-43
2155780-3	1990	Heterologous expression of the human alpha 1 and alpha 2 subunits in Xenopus oocytes resulted in the formation of glycine-gated strychnine-sensitive chloride channels, indicating that both polypeptides can form functional GlyRs.	Glycine	114-121	adrenoceptor alpha 1D	Homo sapiens	37-56
17452339-1	2007	Glutathione is essential for maintaining the intracellular redox environment and is synthesized from gamma-glutamylcysteine, glycine, and ATP by glutathione synthetase (GS).	Glycine	125-132	glutathione synthetase 2	Arabidopsis thaliana	145-167
1690430-12	1990	These results indicate that glycine has at least two actions at the NMDA receptor: it enables channel opening by the agonist and decreases desensitization.	Glycine	28-35	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	68-81
17372332-0	2007	Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function.	Glycine	39-46	scavenger receptor class B member 1	Homo sapiens	54-59
17372332-2	2007	Recently, we characterized a mutant, G420H, which replaced glycine 420 in the extracellular domain of SR-BI with a histidine residue and had a profound effect on SR-BI function.	Glycine	59-66	scavenger receptor class B member 1	Homo sapiens	102-107
17372332-2	2007	Recently, we characterized a mutant, G420H, which replaced glycine 420 in the extracellular domain of SR-BI with a histidine residue and had a profound effect on SR-BI function.	Glycine	59-66	scavenger receptor class B member 1	Homo sapiens	162-167
2166246-4	1990	[3H]Glycine interacted with a single population of sites having a KD of approximately 200 nM and a maximum density of 6.2 pmol/mg protein (stratum radiatum, CA1).	Glycine	4-11	carbonic anhydrase 1	Rattus norvegicus	157-160
17383967-2	2007	There are two Na(+)/Cl(-)-dependent glycine transporters, GLYT1 and GLYT2, which control extracellular glycine concentrations and these transporters show differences in substrate selectivity and blocker sensitivity.	Glycine	36-43	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	68-73
17383967-5	2007	In this report, we demonstrate that the LeuT(Aa) structure represents a good working model of the Na(+)/Cl(-)-dependent neurotransmitters and that differences in substrate selectivity can be attributed to a single difference of a glycine residue in transmembrane domain 6 of GLYT1 for a serine residue at the corresponding position of GLYT2.	Glycine	230-237	Leucine transport, high	Homo sapiens	40-44
17383967-5	2007	In this report, we demonstrate that the LeuT(Aa) structure represents a good working model of the Na(+)/Cl(-)-dependent neurotransmitters and that differences in substrate selectivity can be attributed to a single difference of a glycine residue in transmembrane domain 6 of GLYT1 for a serine residue at the corresponding position of GLYT2.	Glycine	230-237	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	335-340
17434045-5	2007	In this report, we describe a Chinese-Singaporean family with EBP in whom an autosomal dominant glycine substitution mutation, p.G2251E, was identified in exon 86 of the COL7A1 gene.	Glycine	96-103	collagen type VII alpha 1 chain	Homo sapiens	170-176
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	60-63	annexin A7	Homo sapiens	98-105
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	annexin A7	Homo sapiens	98-105
30170631-7	2018	Pathway analysis revealed alterations in various metabolic pathways (e.g., glycine, choline and methionine degradation, dipthamide biosynthesis and glycolysis pathways, among others) between IDH-mutant and IDH-wildtype gliomas.	Glycine	75-82	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	191-194
34969185-2	2021	The SLC6A20 protein product (Sodium-dependent Imino Transporter 1 (SIT1)) is involved in the transport of amino acids, including glycine.	Glycine	129-136	solute carrier family 6 member 20	Homo sapiens	4-11
17174105-3	2007	Most have employed recombinant proteases based on an expression strategy we developed which links the essential hydrophilic cofactor domain within NS2B to the NS3 protease domain by a flexible glycine linker.	Glycine	193-200	KRAS proto-oncogene, GTPase	Homo sapiens	159-162
17337448-9	2007	A second site at Arg(459) decreasing Gly(460) within the C-terminal helicase region of NS3 was cleaved more slowly.	Glycine	37-40	KRAS proto-oncogene, GTPase	Homo sapiens	87-90
17394124-9	2007	Results of the deactivation tests and the effect of lactose on macrophage migration showed that a lactose-insensitive receptor which mainly recognizes Ala-Gly-Val-Pro-Gly-Ile-Gly-Val-Gly is presumably present on the membrane of macrophages in addition to the elastin-binding protein (EBP) sensitive to lactose.	Glycine	155-158	EBP cholestenol delta-isomerase	Homo sapiens	259-282
17394124-9	2007	Results of the deactivation tests and the effect of lactose on macrophage migration showed that a lactose-insensitive receptor which mainly recognizes Ala-Gly-Val-Pro-Gly-Ile-Gly-Val-Gly is presumably present on the membrane of macrophages in addition to the elastin-binding protein (EBP) sensitive to lactose.	Glycine	155-158	EBP cholestenol delta-isomerase	Homo sapiens	284-287
17268153-4	2007	This review introduces our approaches that employ an Arg-Gly-Asp (RGD) fiber-mutant adenovirus vector encoding the chemokine or chemokine receptor gene in cancer immunotherapy.	Glycine	57-60	C-X-C motif chemokine receptor 4	Homo sapiens	128-146
17172352-5	2006	Metabolite profiling of tha1 mutants identified a &gt;50-fold increase in the seed Thr content, a 50% decrease in seedling Gly content, and few other significant metabolic changes.	Glycine	123-126	threonine aldolase 1	Arabidopsis thaliana	24-28
17172352-7	2006	Rescue of tha2 mutants and tha1 tha2 double mutants by overproduction of feedback-insensitive Thr deaminase (OMR1) shows that Gly formation by THA1 and THA2 is not essential in Arabidopsis.	Glycine	126-129	threonine aldolase 1	Arabidopsis thaliana	27-36
17172352-7	2006	Rescue of tha2 mutants and tha1 tha2 double mutants by overproduction of feedback-insensitive Thr deaminase (OMR1) shows that Gly formation by THA1 and THA2 is not essential in Arabidopsis.	Glycine	126-129	L-O-methylthreonine resistant 1	Arabidopsis thaliana	109-113
17172352-7	2006	Rescue of tha2 mutants and tha1 tha2 double mutants by overproduction of feedback-insensitive Thr deaminase (OMR1) shows that Gly formation by THA1 and THA2 is not essential in Arabidopsis.	Glycine	126-129	threonine aldolase 1	Arabidopsis thaliana	143-147
17229600-0	2006	A glycine substitution in the COL7A1 gene causes mild RDEB in a Pakistani family.	Glycine	2-9	collagen type VII alpha 1 chain	Homo sapiens	30-36
17229600-3	2006	Typically, the dominant forms (DDEB) result from glycine substitutions within COL7A1, whereas other glycine mutations are "silent" in the heterozygous state and produce disease only when they are homozygous.	Glycine	49-56	collagen type VII alpha 1 chain	Homo sapiens	78-84
17229600-5	2006	We identified a new glycine substitution within the collagenous region in exon 94 of the COL7A1 gene.	Glycine	20-27	collagen type VII alpha 1 chain	Homo sapiens	89-95
17229600-7	2006	This finding expands the allelic series of COL7A1 mutations underlying mild recessive dystrophic epidermolysis bullosa (RDEB) and sheds further light upon regions of the type VII collagen triple helix that are tolerant of heterozygous glycine substitutions.	Glycine	235-242	collagen type VII alpha 1 chain	Homo sapiens	43-49
17000703-8	2006	Since Gly-386 and Gly-409 reside in the conserved activation segment of the kinase domain, the results suggest that the activation segment is a regulatory switch governing PINK1 kinase activity.	Glycine	6-9	PTEN induced kinase 1	Homo sapiens	172-177
17000703-8	2006	Since Gly-386 and Gly-409 reside in the conserved activation segment of the kinase domain, the results suggest that the activation segment is a regulatory switch governing PINK1 kinase activity.	Glycine	18-21	PTEN induced kinase 1	Homo sapiens	172-177
17035525-1	2006	The neuron-specific K+-Cl- cotransporter KCC2 extrudes Cl- and renders GABA and glycine action hyperpolarizing.	Glycine	80-87	solute carrier family 12 member 5	Homo sapiens	41-45
16965438-0	2006	Glycine substitution mutations by different amino acids at the same codon in COL7A1 cause different modes of dystrophic epidermolysis bullosa inheritance.	Glycine	0-7	collagen type VII alpha 1 chain	Homo sapiens	77-83
16691402-5	2006	RESULTS AND DISCUSSION: Sequencing of the KCNQ2 gene revealed that all 17 affected family members carried a heterozygous Gly-to-Val (G271V) mutation in the conserved pore region that resulted from a guanine-to-thymine transition in exon 5 of KCNQ2.	Glycine	121-124	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	42-47
16691402-5	2006	RESULTS AND DISCUSSION: Sequencing of the KCNQ2 gene revealed that all 17 affected family members carried a heterozygous Gly-to-Val (G271V) mutation in the conserved pore region that resulted from a guanine-to-thymine transition in exon 5 of KCNQ2.	Glycine	121-124	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	242-247
16954346-2	2006	We show that in mammalian fibroblasts, cytoplasmic linker protein (CLIP) 170 and other microtubule plus-end tracking proteins comprising a cytoskeleton-associated protein glycine-rich (CAP-Gly) microtubule binding domain such as CLIP-115 and p150 Glued, localize to the ends of tyrosinated microtubules but not to the ends of detyrosinated microtubules.	Glycine	171-178	CAP-Gly domain containing linker protein 1	Homo sapiens	39-76
16954346-2	2006	We show that in mammalian fibroblasts, cytoplasmic linker protein (CLIP) 170 and other microtubule plus-end tracking proteins comprising a cytoskeleton-associated protein glycine-rich (CAP-Gly) microtubule binding domain such as CLIP-115 and p150 Glued, localize to the ends of tyrosinated microtubules but not to the ends of detyrosinated microtubules.	Glycine	189-192	CAP-Gly domain containing linker protein 1	Homo sapiens	39-76
16954346-5	2006	These results indicate that tubulin tyrosination regulates microtubule interactions with CAP-Gly microtubule plus-end tracking proteins and provide explanations for the involvement of TTL in tumor progression and in neuronal organization.	Glycine	93-96	tubulin tyrosine ligase	Homo sapiens	184-187
16900509-5	2006	The most frequent mutations were GGT-&gt;GAT (Gly-&gt;Asp) (37.5%), followed by GGT-&gt;GTT (Gly-&gt;Val) (31.3%), both in codon 12.	Glycine	46-49	glycine-N-acyltransferase	Homo sapiens	41-44
17009846-1	2006	Integrin alphavbeta3 plays a significant role in tumor angiogenesis and is a receptor for the extracellular matrix proteins with the exposed arginine-glycine-aspartic (RGD) tripeptide sequence.	Glycine	150-157	integrin subunit alpha V	Homo sapiens	0-20
17063874-4	2006	During the process of TTR analysis, we found unique isoforms of TTR, which showed changes of the cysteine (10th from amino terminal) residue to glycine, dehydroalanine, and S-sulfocysteine residues.	Glycine	144-151	transthyretin	Homo sapiens	22-25
17063874-4	2006	During the process of TTR analysis, we found unique isoforms of TTR, which showed changes of the cysteine (10th from amino terminal) residue to glycine, dehydroalanine, and S-sulfocysteine residues.	Glycine	144-151	transthyretin	Homo sapiens	64-67
16738539-8	2006	Furthermore, we clarified the mechanism of enhanced glycylsarcosine (Gly-Sar) transport activity in PEPT2-expressing HEK293 cells after the PDZK1 coexpression.	Glycine	69-72	PDZ domain containing 1	Homo sapiens	140-145
16858129-3	2006	The Thr(201)Lys and Met(260)Val also presented together with known SNPs (Glu(158)Lys-Glu(308)Gly and Val(257)Met, respectively) in the same alleles of the FMO3 gene to form novel haplotypes.	Glycine	93-96	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	155-159
16722632-4	2006	Peptide analogues containing C(alpha alpha)-dialkylated glycine (Aaa1, 1) or C(alpha)-alkylated glycine (Aaa2, 2) amino acid residues showed antitumor activity against melanoma, larynx carcinoma, colon carcinomas, and colon metastasis cell lines in vitro.	Glycine	56-63	AAA1	Homo sapiens	65-69
16734764-2	2006	As the transport process performed by SNAT2 is highly energized, system A substrates, such as glutamine, glycine, proline and alanine, reach high transmembrane gradients and constitute major components of the intracellular amino acid pool.	Glycine	105-112	solute carrier family 38 member 2	Homo sapiens	38-43
17193285-8	2006	We conclude that 5-methyl-1H-imidazole and glycine mimic the substrate and occupy the active site of HAL in a similar orientation.	Glycine	43-50	histidine ammonia-lyase	Homo sapiens	101-104
16672841-1	2006	INTRODUCTION: Several common polymorphisms of the beta2 adrenergic (ADRB2) have been described including a Glycine (Gly) for arginine (Arg) substitution at amino acid 16.	Glycine	107-114	adrenoceptor beta 2	Homo sapiens	68-73
16672841-1	2006	INTRODUCTION: Several common polymorphisms of the beta2 adrenergic (ADRB2) have been described including a Glycine (Gly) for arginine (Arg) substitution at amino acid 16.	Glycine	107-110	adrenoceptor beta 2	Homo sapiens	68-73
16596194-3	2006	Two alternatively spliced IGF1R mRNA transcripts have been described to differ by only three nucleotides (CAG) in the coding sequence, resulting in an amino-acid change from the originally described Thr-Gly to an Arg in the extracellular portion of the receptor beta subunit.	Glycine	203-206	insulin like growth factor 1 receptor	Homo sapiens	26-31
16484215-4	2006	The function of HSP47 relies on its specific interaction with correctly folded triple-helical regions comprised of Gly-Xaa-Yaa repeats, and Arg residues at Yaa positions have been shown to be important for this interaction.	Glycine	115-118	serpin family H member 1	Homo sapiens	16-21
19504432-6	2009	This mutation resulted in a substitution of glycine (GGC) to aspartic acid (GAC) at the protein level.None of the healthy family members, or any of the 100 control subjects carried this mutation.	Glycine	44-51	gamma-glutamylcyclotransferase	Homo sapiens	53-56
19309309-6	2009	A GST (glutathione transferase) pulldown assay using different deletion mutants revealed that the RGG (Arg-Gly-Gly) region of RHA was responsible for the interaction with beta-actin, and this dominant-negative mutant reduced the recruitment of Pol II (RNA polymerase II) into PICs.	Glycine	107-110	POTE ankyrin domain family member F	Homo sapiens	171-181
19309309-6	2009	A GST (glutathione transferase) pulldown assay using different deletion mutants revealed that the RGG (Arg-Gly-Gly) region of RHA was responsible for the interaction with beta-actin, and this dominant-negative mutant reduced the recruitment of Pol II (RNA polymerase II) into PICs.	Glycine	111-114	POTE ankyrin domain family member F	Homo sapiens	171-181
19420222-3	2009	The major N-terminal acetyltransferase (NAT), NatA, acts on subclasses of proteins with Ser-, Ala-, Thr-, Gly-, Cys- and Val- N termini.	Glycine	106-109	bromodomain containing 2	Homo sapiens	40-43
19029431-8	2009	Despite similar clinical asthma scores on hospital admission, the children with the Gly/Gly genotype had significantly shorter hospital ICU length of stay and duration of continuously nebulized albuterol therapy and were significantly less likely to require IV beta(2)-AR therapy than those with Arg/Arg or Arg/Gly genotypes.	Glycine	84-87	adrenoceptor beta 2	Homo sapiens	261-271
19029431-8	2009	Despite similar clinical asthma scores on hospital admission, the children with the Gly/Gly genotype had significantly shorter hospital ICU length of stay and duration of continuously nebulized albuterol therapy and were significantly less likely to require IV beta(2)-AR therapy than those with Arg/Arg or Arg/Gly genotypes.	Glycine	88-91	adrenoceptor beta 2	Homo sapiens	261-271
19029431-8	2009	Despite similar clinical asthma scores on hospital admission, the children with the Gly/Gly genotype had significantly shorter hospital ICU length of stay and duration of continuously nebulized albuterol therapy and were significantly less likely to require IV beta(2)-AR therapy than those with Arg/Arg or Arg/Gly genotypes.	Glycine	88-91	adrenoceptor beta 2	Homo sapiens	261-271
19029431-10	2009	CONCLUSIONS: In this cohort of children with severe asthma exacerbations, children whose genotypes were homozygous for Gly at amino acid position 16 of the beta(2)-AR gene had a more rapid response to beta(2)-AR agonist treatment.	Glycine	119-122	adrenoceptor beta 2	Homo sapiens	156-166
19029431-10	2009	CONCLUSIONS: In this cohort of children with severe asthma exacerbations, children whose genotypes were homozygous for Gly at amino acid position 16 of the beta(2)-AR gene had a more rapid response to beta(2)-AR agonist treatment.	Glycine	119-122	adrenoceptor beta 2	Homo sapiens	201-211
19393096-9	2009	(iii) The code rapidly developed into a four-column code where all codons in the same column coded for the same amino acid: NUN = Val, NCN = Ala, NAN = Asp and/or Glu, and NGN = Gly.	Glycine	178-181	neogenin 1	Homo sapiens	172-175
19176531-5	2009	Despite the trajectory of the methyl group, we observed an increase in the C20-Gly(188) (EL2) distance consistent with an increase in separation between the retinal and EL2 upon activation.	Glycine	79-82	spectrin alpha, erythrocytic 1	Homo sapiens	89-92
19102727-9	2009	Mutations of the three glycine residues (Gly(43), Gly(47) and Gly(49)) in the predicted cofactor-binding motif (Gly-Xaa(3)-Gly-Xaa-Gly) of RDH10 abolished its enzymatic activity, suggesting that the cofactor-binding motif is essential for its activity.	Glycine	23-30	retinol dehydrogenase 10	Homo sapiens	139-144
19102727-9	2009	Mutations of the three glycine residues (Gly(43), Gly(47) and Gly(49)) in the predicted cofactor-binding motif (Gly-Xaa(3)-Gly-Xaa-Gly) of RDH10 abolished its enzymatic activity, suggesting that the cofactor-binding motif is essential for its activity.	Glycine	41-44	retinol dehydrogenase 10	Homo sapiens	139-144
19226165-4	2009	Depending on the NSG substituent, certain of these hybrids exhibited up to 40-fold higher Shc SH2 domain-binding affinity than the parent Gly-containing peptide (IC50 = 248 microM) (for example, for N-homoallyl analogue 50, IC50 = 6 microM).	Glycine	138-141	SHC adaptor protein 1	Homo sapiens	90-93
19361447-11	2009	The latter stabilizes the glycine-rich loop in the extended active conformation known from the majority of CK2alpha structures.	Glycine	26-33	casein kinase 2 alpha 2	Homo sapiens	107-115
19014993-7	2009	This observation was verified by the differential capacity of Gly-tRNA(Gly) molecules to form ternary complexes with activated S. aureus EF-Tu.GTP.	Glycine	62-65	AT695_RS00230	Staphylococcus aureus	66-75
19014993-9	2009	Both bioinformatic and biochemical data suggest that in S. aureus these three glycylated tRNA(Gly) isoacceptors that are weak EF-Tu binders, possibly escape protein synthesis and serve as glycine donors for the formation of pentaglycine bridges that are essential for stabilization of the staphylococcal cell wall.	Glycine	188-195	AT695_RS00230	Staphylococcus aureus	89-98
19170548-1	2009	The peptide C-terminal amide group essential for the full biological activity of many peptide hormones is produced by consecutive actions of peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidylamidoglycolate lyase (PAL); PHM catalyzes the hydroxylation of C-terminal glycine, and PAL decomposes the peptidyl-alpha-hydroxyglycine to an amidated peptide and glyoxylate.	Glycine	149-156	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	192-195
19170548-1	2009	The peptide C-terminal amide group essential for the full biological activity of many peptide hormones is produced by consecutive actions of peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidylamidoglycolate lyase (PAL); PHM catalyzes the hydroxylation of C-terminal glycine, and PAL decomposes the peptidyl-alpha-hydroxyglycine to an amidated peptide and glyoxylate.	Glycine	149-156	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	237-240
19193893-3	2009	NR2B-containing NMDARs, for example, exhibit relatively high affinity both for glutamate and the coagonist glycine.	Glycine	107-114	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	0-4
19136952-2	2009	We carried out genome-wide linkage analysis and identified five disease-segregating mutations affecting the CAP-Gly domain of dynactin (encoded by DCTN1) in eight families with Perry syndrome; these mutations diminish microtubule binding and lead to intracytoplasmic inclusions.	Glycine	112-115	dynactin subunit 1	Homo sapiens	147-152
34969185-4	2021	Recently, it was also proposed that SLC6A20 represents the novel regulator of glycine levels and that glycine has beneficial effects against the proinflammatory cytokine secretion induced by SARS-CoV-2 infection.	Glycine	78-85	solute carrier family 6 member 20	Homo sapiens	36-43
19105697-7	2009	Crystallization of OAT2 in the presence of N-alpha-acetyl-L-glutamate led to a structure in which Thr-181 was acetylated; the carbonyl oxygen of the acyl-enzyme complex was located in an oxyanion hole and positioned to hydrogen bond with the backbone amide NH of Gly-112 and the alcohol of Thr-111.	Glycine	263-266	solute carrier family 22 member 7	Homo sapiens	19-23
34977503-4	2022	Low glycine doses enhance NMDAR function, whereas high doses trigger glycine-induced NMDAR internalization (GINI) in vitro.	Glycine	4-11	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	26-31
20641947-0	2004	(99m)Tc Nitrido(diphosphine)-Cys-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2).	Glycine	58-61	gastrin releasing peptide	Homo sapiens	92-100
20641947-0	2004	(99m)Tc Nitrido(diphosphine)-Cys-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2).	Glycine	58-61	gastrin releasing peptide	Homo sapiens	164-189
20641947-0	2004	(99m)Tc Nitrido(diphosphine)-Cys-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2).	Glycine	58-61	gastrin releasing peptide	Homo sapiens	191-194
34977503-4	2022	Low glycine doses enhance NMDAR function, whereas high doses trigger glycine-induced NMDAR internalization (GINI) in vitro.	Glycine	69-76	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	85-90
34977503-6	2022	Mice pretreated with a GlyT1-A, which increases synaptic glycine levels, exhibited smaller stroke volume, reduced cell death, and minimized behavioral deficits following stroke induction by either photothrombosis or endothelin-1.	Glycine	57-64	endothelin 1	Mus musculus	216-228
33975519-4	2021	Using the insertion of glycine residues at each corner of the triangular-shaped anchor domain to decouple this domain we provide evidence that the anchor is important in Piezo1 mechano-gating.	Glycine	23-30	piezo type mechanosensitive ion channel component 1	Homo sapiens	170-176
19197535-7	2009	All 27 individuals with EB pruriginosa were heterozygous for dominant-negative glycine substitution mutations in the COL7A1 gene, six of which have not been reported previously.	Glycine	79-86	collagen type VII alpha 1 chain	Homo sapiens	117-123
19400088-0	2009	Monitoring peptide folding by time-resolved spectroscopies: the effect of a single Gly to Aib substitution.	Glycine	83-86	ANIB1	Homo sapiens	90-93
19958195-0	2009	HB Fannin-Lubbock-I with a single GGC&gt;GAC mutation at beta119(GH2)Gly--&gt;Asp in a homozygous Mexican patient.	Glycine	69-72	growth hormone 2	Homo sapiens	65-68
18768736-0	2008	The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine.	Glycine	121-128	solute carrier family 6 member 17	Rattus norvegicus	28-32
18768736-0	2008	The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine.	Glycine	121-128	solute carrier family 6 member 17	Rattus norvegicus	34-41
18768736-3	2008	Here, we provide evidence indicating that Rxt1/NTT4 functions as a vesicular transporter selective for proline, glycine, leucine, and alanine.	Glycine	112-119	solute carrier family 6 member 17	Rattus norvegicus	47-51
18768736-5	2008	Small interfering RNA (siRNA)-mediated knockdown of Rxt1/NTT4 in PC12 cells resulted in selective reductions in uptake levels for proline, glycine, leucine, and alanine.	Glycine	139-146	solute carrier family 6 member 17	Rattus norvegicus	57-61
18768736-9	2008	These data indicate that the orphan Rxt1/NTT4 protein functions as a vesicular transporter for proline, glycine, leucine, and alanine, further suggesting its important role in synaptic transmission.	Glycine	104-111	solute carrier family 6 member 17	Rattus norvegicus	41-45
18784085-1	2008	To test the hypothesis that factor Xa (fXa) interacts with protein S, fXa was labeled active-site specifically with a dansyl (D) dye via a Glu-Gly-Arg (EGR) tether to yield DEGR-fXa(i).	Glycine	143-146	coagulation factor X	Homo sapiens	28-37
18784085-1	2008	To test the hypothesis that factor Xa (fXa) interacts with protein S, fXa was labeled active-site specifically with a dansyl (D) dye via a Glu-Gly-Arg (EGR) tether to yield DEGR-fXa(i).	Glycine	143-146	coagulation factor X	Homo sapiens	39-42
18784085-1	2008	To test the hypothesis that factor Xa (fXa) interacts with protein S, fXa was labeled active-site specifically with a dansyl (D) dye via a Glu-Gly-Arg (EGR) tether to yield DEGR-fXa(i).	Glycine	143-146	coagulation factor X	Homo sapiens	70-73
18784085-1	2008	To test the hypothesis that factor Xa (fXa) interacts with protein S, fXa was labeled active-site specifically with a dansyl (D) dye via a Glu-Gly-Arg (EGR) tether to yield DEGR-fXa(i).	Glycine	143-146	coagulation factor X	Homo sapiens	70-73
20641607-12	2004	(177)Lu-AMBA consists of two components: a peptide of eight amino acids that is composed of the seven common amino acids in the C-terminus of BBN/GRP (Trp-Ala-Val-Gly-His-Leu-Met) and a complex of (177)Lu-DOTA attached to the N-terminus of the peptide via a glycyl-4-aminobezoic acid linker.	Glycine	163-166	gastrin releasing peptide	Homo sapiens	142-149
33975519-5	2021	Insertion of two extra glycine residues between the anchor and the outer helix of human Piezo1 causes abrogated inactivation and reduced mechanosensitivity.	Glycine	23-30	piezo type mechanosensitive ion channel component 1	Homo sapiens	88-94
34488161-10	2021	Low-dose PCB126 exposure increased glycine and threonine, the amino acids necessary for the productions of collagen and elastin.	Glycine	35-42	elastin	Mus musculus	120-127
34525858-3	2021	Besides, similar to PBA, D4F inhibited gly-HDL-induced ER stress response activation evaluated through the decreased PERK and eIF2alpha phosphorylation, together with reduced ATF6 nuclear translocation as well as the downregulation of GRP78 and CHOP.	Glycine	39-42	DNA-damage inducible transcript 3	Mus musculus	245-249
34525858-4	2021	Interestingly, D4F facilitated gly-HDL-triggered activation of autophagy, measured as elevated levels of beclin-1, LC3-II, and ATG5 expressions in macrophages.	Glycine	31-34	beclin 1, autophagy related	Mus musculus	105-113
34525858-4	2021	Interestingly, D4F facilitated gly-HDL-triggered activation of autophagy, measured as elevated levels of beclin-1, LC3-II, and ATG5 expressions in macrophages.	Glycine	31-34	microtubule-associated protein 1 light chain 3 alpha	Mus musculus	115-118
34525858-5	2021	Furthermore, the inhibition effect of D4F on gly-HDL-induced ER stress-CHOP-induced apoptosis of macrophages was restrained after beclin-1 siRNA and 3-methyladenine (3-MA, an inhibitor of autophagy) treatments, while this effect was further reinforced after rapamycin (Rapa, an inducer of autophagy) treatment.	Glycine	45-48	DNA-damage inducible transcript 3	Mus musculus	71-75
34525858-5	2021	Furthermore, the inhibition effect of D4F on gly-HDL-induced ER stress-CHOP-induced apoptosis of macrophages was restrained after beclin-1 siRNA and 3-methyladenine (3-MA, an inhibitor of autophagy) treatments, while this effect was further reinforced after rapamycin (Rapa, an inducer of autophagy) treatment.	Glycine	45-48	beclin 1, autophagy related	Mus musculus	130-138
34525858-8	2021	These results support that D4F effectively protects macrophages against gly-HDL-induced ER stress-CHOP-mediated apoptosis by promoting autophagy.	Glycine	72-75	DNA-damage inducible transcript 3	Mus musculus	98-102
34646012-5	2021	Here we show that the cytokine-binding segments of human ALK and LTK comprise a novel architectural chimera of a permuted TNF-like module that braces a glycine-rich subdomain featuring a hexagonal lattice of long polyglycine type II helices.	Glycine	152-159	leukocyte receptor tyrosine kinase	Homo sapiens	65-68
34917610-11	2021	Apoptosis-related indexes (Caspase 3 activity and Annexin-V) and gene expression Bax, Cyto C, and Caspase 3) were significantly increased in the TG group, but they could be restored by adding Gly.	Glycine	192-195	annexin A5	Homo sapiens	50-59
34757085-5	2022	Then, in the ventral horn, microglia were activated, and expression of choline acetyltransferase (ChAT), a synthetic enzyme of acetylcholine, and potassium chloride co-transporter 2 (KCC2), which shifts the action of gamma-amino butyric acid (GABA) and glycine to inhibitory, decreased.	Glycine	253-260	solute carrier family 12, member 5	Mus musculus	183-187
34757085-9	2022	The KCC2 level sufficiently recovered when axonal regeneration was complete, suggesting that the excitatory action of GABA/glycine may participate in axonal regeneration.	Glycine	123-130	solute carrier family 12, member 5	Mus musculus	4-8
34630451-5	2021	N-myristoylation at glycine-2 is essential for plasma membrane association and recruiting SOS2 to activate SOS1, whereas S-acylation at cysteine-3 redirects SOS3 toward the nucleus.	Glycine	20-27	sodium proton exchanger, putative (NHX7) (SOS1)	Arabidopsis thaliana	107-111
34447991-2	2021	It has been shown that upon eIF5A depletion, yeast ribosomes stall in polyproline motifs, but also in tripeptide sequences that combine proline with glycine and charged amino acids.	Glycine	149-156	eukaryotic translation initiation factor 5A	Homo sapiens	28-33
34400248-3	2021	N, N-dimethylglycine (DMG) is a nutrient supplement and acts as an NMDAR glycine site partial agonist.	Glycine	73-80	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	67-72
16282361-3	2006	In the present study, using inside-out membrane vesicles, we demonstrated that human ABCC4 in the presence of physiological concentrations of GSH has a high affinity for the taurine and glycine conjugates of the common natural bile acids as well as the unconjugated bile acid cholate.	Glycine	186-193	ATP binding cassette subfamily C member 4	Homo sapiens	85-90
16571957-15	2006	CONCLUSIONS: Glycine at position 16 and/or glutamate at position 27 of the beta2AR leads to lower vasopressor use for treatment of hypotension during spinal anesthesia.	Glycine	13-20	adrenoceptor beta 2	Homo sapiens	75-82
34526091-5	2021	Intraperitoneal injections of the GABA A receptor (GABAAR) antagonist picrotoxin and the glycine receptor antagonist brucine rapidly dephosphorylated eEF2.	Glycine	89-96	eukaryotic translation elongation factor 2	Mus musculus	150-154
16516876-1	2006	Complete 1H and 13C resonance assignments were made for a new type of 3 beta,7 beta-dihydroxy-5-cholen-24-oic acid doubly conjugated with sulfuric acid at C-3 and N-acetylglucosamine at C-7 and its glycine- and taurine-amidated triple-conjugates by the combined use of several homonuclear and heteronuclear shift-correlated 2D NMR techniques.	Glycine	198-205	complement C3	Homo sapiens	155-158
34400539-6	2021	RESULTS: COL4A3-COL4A5 variants resulting in position 1 Gly substitutions were confirmed to be associated with hematuria (for each, P<0.001).	Glycine	56-59	collagen type IV alpha 3 chain	Homo sapiens	9-15
16609991-0	2006	Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells.	Glycine	0-7	phosphoinositide-3-kinase regulatory subunit 2	Homo sapiens	83-86
34400539-6	2021	RESULTS: COL4A3-COL4A5 variants resulting in position 1 Gly substitutions were confirmed to be associated with hematuria (for each, P<0.001).	Glycine	56-59	collagen type IV alpha 5 chain	Homo sapiens	16-22
16326905-6	2006	Mutation of the putative Gly hinge to Ala in KCNQ2 (Kv7.2) abolished channel function.	Glycine	25-28	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	45-50
16326905-6	2006	Mutation of the putative Gly hinge to Ala in KCNQ2 (Kv7.2) abolished channel function.	Glycine	25-28	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	52-57
34528455-5	2021	DRD2 -141 (rs1799732) Ins, A-241G (rs1799978) G, DRD3 Ser9Gly (rs6280) Gly, HTR2A rs7997012 A, ABCB1 C3435T (rs1045642) T and G2677T/A (rs2032582) T and UGT1A4*3 alleles were related to safety, effectiveness and/or pharmacokinetic variability with moderated level of evidence.	Glycine	71-74	dopamine receptor D3	Homo sapiens	49-53
16635350-6	2006	CONCLUSION: The results indicated that prophylactic or simultaneous treatment with glycine could effectively inhibit LPS-induced KCs activation by inhibiting IRAK-4 expression.	Glycine	83-90	interleukin-1 receptor-associated kinase 4	Mus musculus	158-164
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	Homo sapiens	84-91
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	cell migration inducing hyaluronidase 2	Homo sapiens	96-101
34449768-8	2021	In addition, Gly/Arg genotype of IRS1 gene was associated with significantly higher body mass index, fat mass, %body fat, triglycerides, cholesterol, alkaline phosphate, aspartate transaminase, fasting insulin and HOMA-IR levels in OSA and NAFLD subjects.	Glycine	13-16	insulin receptor substrate 1	Homo sapiens	33-37
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	FAM3 metabolism regulating signaling molecule C	Homo sapiens	209-214
34449768-10	2021	Further we found that subjects carrying IRS1 Gly/Arg (OR 4.49, 95% C.I.	Glycine	45-48	insulin receptor substrate 1	Homo sapiens	40-44
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	FAM3 metabolism regulating signaling molecule D	Homo sapiens	219-224
16406369-1	2006	Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.	Glycine	136-143	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	Homo sapiens	227-234
34449768-11	2021	1.06-12.52, p = 0.002) genotype possess a much higher risk of OSA and NAFLD compared to IRS2 Gly/Asp (OR 1.01, 95% C.I.	Glycine	93-96	insulin receptor substrate 2	Homo sapiens	88-92
34449768-13	2021	In sub group analysis of IRS1 Gly/Arg have significant differences between the mild, moderate and severe group (P<0.05).	Glycine	30-33	insulin receptor substrate 1	Homo sapiens	25-29
34399745-11	2021	Furthermore, the addition of glycine was shown to improve hGH secretion onto the culture medium.	Glycine	29-36	gamma-glutamyl hydrolase	Homo sapiens	58-61
17106611-0	2006	Epidermolysis bullosa pruriginosa due to a glycine substitution mutation in the COL7A1-gene.	Glycine	43-50	collagen type VII alpha 1 chain	Homo sapiens	80-86
34387192-6	2021	In that variant, a single replacement of N-latch asparagine with glycine, as present in Cin8, eliminated the additional H-bond stabilization and rescued the functional defects.	Glycine	65-72	kinesin motor protein CIN8	Saccharomyces cerevisiae S288C	88-92
16444815-1	2006	PURPOSE OF REVIEW: Glycine, a non-essential amino acid, has been found to protect against oxidative stress in several pathological situations, and it is required for the biosynthesis of structural proteins such as elastin.	Glycine	19-26	elastin	Rattus norvegicus	214-221
16444815-6	2006	In addition, as glycine is required for a number of critical metabolic pathways, such as the synthesis of the structural proteins collagen and elastin, the perturbation of these leads to impaired elastin formation in the aorta.	Glycine	16-23	elastin	Rattus norvegicus	143-150
16444815-6	2006	In addition, as glycine is required for a number of critical metabolic pathways, such as the synthesis of the structural proteins collagen and elastin, the perturbation of these leads to impaired elastin formation in the aorta.	Glycine	16-23	elastin	Rattus norvegicus	196-203
34439534-1	2021	In Arabidopsis, the cytosolic redox protein thioredoxin h2 (Trx-h2) is anchored to the cytoplasmic endomembrane through the myristoylated second glycine residue (Gly2).	Glycine	145-152	thioredoxin 2	Arabidopsis thaliana	44-58
34439534-1	2021	In Arabidopsis, the cytosolic redox protein thioredoxin h2 (Trx-h2) is anchored to the cytoplasmic endomembrane through the myristoylated second glycine residue (Gly2).	Glycine	145-152	thioredoxin 2	Arabidopsis thaliana	60-66
16367955-1	2006	Serine hydroxymethyltransferase (SHMT) is part of the mitochondrial enzyme complex catalysing the photorespiratory production of serine, ammonium and CO(2) from glycine.	Glycine	161-168	serine hydroxymethyltransferase, mitochondrial	Solanum tuberosum	0-31
18760921-2	2008	It promotes the PLP-dependent aldol condensation of glycine with a range of aromatic aldehydes.	Glycine	52-59	proteolipid protein 1	Homo sapiens	16-19
16367955-1	2006	Serine hydroxymethyltransferase (SHMT) is part of the mitochondrial enzyme complex catalysing the photorespiratory production of serine, ammonium and CO(2) from glycine.	Glycine	161-168	serine hydroxymethyltransferase, mitochondrial	Solanum tuberosum	33-37
34445081-9	2021	Uterus IRI led to increased myeloperoxidase expression, which was significantly reduced by melatonin (p = 0.004), glycine (p < 0.001) or their combination (p < 0.001).	Glycine	114-121	myeloperoxidase	Rattus norvegicus	28-43
16367955-5	2006	SHMT antisense plants displayed lower photosynthetic capacity and accumulated glycine in light.	Glycine	78-85	serine hydroxymethyltransferase, mitochondrial	Solanum tuberosum	0-4
16332456-4	2005	ATP-dependent uptake of radiolabeled glycine-, taurine-conjugated bile salts, and [(3)H]cholate was observed when hBSEP or rBsep was expressed.	Glycine	37-44	ATP binding cassette subfamily B member 11	Homo sapiens	114-119
18842019-3	2008	In this study, we used a melittin analogue that is covalently labeled at its amino terminal (Gly-1) with the environment-sensitive 1-dimethylamino-5-sulfonylnaphthalene (dansyl) group to obtain information regarding the orientation and dynamics of the amino terminal region of membrane-bound melittin.	Glycine	93-96	melittin	Apis mellifera	25-33
18601653-5	2008	Epitope mapping using a series of CD151 mutants with substitutions at amino acid residues that are not conserved between human and mouse CD151 revealed that Gly(176)/Gly(177), Leu(191) and Gln(194) comprise epitopes characteristic of Group-1 mAbs.	Glycine	157-160	CD151 molecule (Raph blood group)	Homo sapiens	34-39
16332456-5	2005	Comparison of initial uptake rates indicated that for both transporters, taurine-conjugated bile salts were transported more rapidly than glycine-conjugated bile salts, however, hBSEP transported glycine conjugates to an extent that was approximately 2-fold greater than rBsep.	Glycine	138-145	ATP binding cassette subfamily B member 11	Homo sapiens	178-183
16332456-5	2005	Comparison of initial uptake rates indicated that for both transporters, taurine-conjugated bile salts were transported more rapidly than glycine-conjugated bile salts, however, hBSEP transported glycine conjugates to an extent that was approximately 2-fold greater than rBsep.	Glycine	196-203	ATP binding cassette subfamily B member 11	Homo sapiens	178-183
16332456-8	2005	In conclusion, both hBSEP and rBsep transport taurine-conjugated bile salts better than glycine-conjugated bile salts, but hBSEP transports glycine conjugates to a greater extent as compared to rBsep.	Glycine	140-147	ATP binding cassette subfamily B member 11	Homo sapiens	123-128
18601653-5	2008	Epitope mapping using a series of CD151 mutants with substitutions at amino acid residues that are not conserved between human and mouse CD151 revealed that Gly(176)/Gly(177), Leu(191) and Gln(194) comprise epitopes characteristic of Group-1 mAbs.	Glycine	166-169	CD151 molecule (Raph blood group)	Homo sapiens	34-39
34233759-6	2021	RESULTS: Thirteen metabolites were identified as common biomarkers discriminating ob/ob mice and lepb-/- zebrafish larvae from their respective wild type controls: alanine, citrulline, ethanolamine, glutamine, glycine, histidine, isoleucine, leucine, methionine, phenylalanine, putrescine, serine and threonine.	Glycine	210-217	leptin	Mus musculus	82-84
19301767-6	2008	Interactions that increased the risk for HF were found in patients carrying at least one of the beta2-AR Glu and beta2-AR Gly allele (OR = 3.81; 95% CI = 1.50-0.70) and beta2-AR Glu and beta1-AR Gly allele combination (OR = 5.51; 95% CI = 2.19-13.86).	Glycine	195-198	adrenoceptor beta 2	Homo sapiens	113-121
34225773-9	2021	Mechanistic investigations reveal tiRNA-Gly directly bind the UHM domain of a splicing-related RNA-binding protein RBM17.	Glycine	40-43	RNA binding motif protein 17	Mus musculus	115-120
18817904-5	2008	The nonsynonymous SNPs with the greatest frequency differences between the Hondo and Ryukyu clusters were the Val/Ala polymorphism (rs3827760) in the EDAR gene, associated with hair thickness, and the Gly/Ala polymorphism (rs17822931) in the ABCC11 gene, associated with ear-wax type.	Glycine	201-204	ATP binding cassette subfamily C member 11	Homo sapiens	242-248
34225773-10	2021	The interaction with tiRNA-Gly could translocate RBM17 from cytoplasm into nucleus.	Glycine	27-30	RNA binding motif protein 17	Mus musculus	49-54
16307739-1	2005	The N-methyl-D-aspartate (NMDA) glutamate receptor possesses an obligatory co-agonist site for D-serine and glycine, named the glycineB site.	Glycine	108-115	glutamate ionotropic receptor NMDA type subunit 2C	Rattus norvegicus	4-50
34225773-11	2021	In addition, tiRNA-Gly increases RBM17 protein expression via inhibiting its degradation in a ubiquitin/proteasome-dependent way.	Glycine	19-22	RNA binding motif protein 17	Mus musculus	33-38
18822216-0	2008	[The effects of glycine on the expression of peroxisome-proliferator-activated receptor gamma in nonalcoholic fatty rat livers].	Glycine	16-23	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	45-93
34225773-13	2021	In vivo mouse model shows that suppression of tiRNA-Gly decreases RBM17 expression.	Glycine	52-55	RNA binding motif protein 17	Mus musculus	66-71
34225773-14	2021	Importantly, tiRNA-Gly can induce exon 16 splicing of MAP4K4 mRNA leading to phosphorylation of downstream signaling pathway, which is RBM17 dependent.	Glycine	19-22	RNA binding motif protein 17	Mus musculus	135-140
18695510-2	2008	The effective synaptic concentrations of glycine are regulated by at least two transporters: glycine transporter 1 and glycine transporter 2.	Glycine	41-48	solute carrier family 6 member 9	Rattus norvegicus	93-114
16380904-9	2005	Three-dimensional modeling of TG5 showed that G113C lies close to the catalytic domain, and, furthermore, that this glycine residue is conserved in all known transglutaminases, which is consistent with pathogenicity.	Glycine	116-123	transglutaminase 5	Homo sapiens	30-33
34225773-15	2021	CONCLUSIONS: Our study firstly illustrates tiRNA-Gly can directly bind to RBM17 and display oncogenic effect via RBM17-mediated alternative splicing.	Glycine	49-52	RNA binding motif protein 17	Mus musculus	74-79
18636091-2	2008	Using ligand binding assays, crystallographic analysis, and all atom MD simulations, we investigate mechanisms underlying the binding by NR3A and NR3B of glycine and D-serine, which are candidate neurotransmitters for NMDA receptors containing NR3 subunits.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	146-150
34225773-15	2021	CONCLUSIONS: Our study firstly illustrates tiRNA-Gly can directly bind to RBM17 and display oncogenic effect via RBM17-mediated alternative splicing.	Glycine	49-52	RNA binding motif protein 17	Mus musculus	113-118
34155405-1	2021	In the present study, we report a human-inherited, impaired, adaptive immunity disorder, which predominantly manifested as a B cell differentiation defect, caused by a heterozygous IKZF3 missense variant, resulting in a glycine-to-arginine replacement within the DNA-binding domain of the encoded AIOLOS protein.	Glycine	220-227	IKAROS family zinc finger 3	Homo sapiens	181-186
18438920-6	2008	Expression of BASP1 mutated at the serine-5 phosphorylation site stimulated neurite outgrowth to a degree comparable to that observed in response to overexpression of wild-type BASP1, whereas expression of BASP1 mutated at the myristoylation site at glycine-1 completely abrogated the stimulatory effects of the protein on neurite outgrowth.	Glycine	250-257	brain abundant, membrane attached signal protein 1	Rattus norvegicus	14-19
16267254-6	2005	METHODS AND RESULTS: In studies with cell types found in vascular tissue, MPO-oxidation products of glycine (formaldehyde) and threonine (acrolein) were the most cytotoxic.	Glycine	100-107	myeloperoxidase	Mus musculus	74-77
15994241-0	2005	Arg16/Gly beta2-adrenergic receptor polymorphism alters the cardiac output response to isometric exercise.	Glycine	6-9	adrenoceptor beta 2	Homo sapiens	10-35
18400471-3	2008	D-serine is primarily transported by Asc-1, and glycine by GlyT1 but maybe also by SNAT2.	Glycine	48-55	solute carrier family 6 member 9	Rattus norvegicus	59-64
34155405-1	2021	In the present study, we report a human-inherited, impaired, adaptive immunity disorder, which predominantly manifested as a B cell differentiation defect, caused by a heterozygous IKZF3 missense variant, resulting in a glycine-to-arginine replacement within the DNA-binding domain of the encoded AIOLOS protein.	Glycine	220-227	IKAROS family zinc finger 3	Homo sapiens	297-303
34155371-2	2021	Thioredoxin h2 (Trx-h2)-a cytosolic redox protein identified as an interacting partner of CBF1-is normally anchored to cytoplasmic endomembranes through myristoylation at the second glycine residue5,6.	Glycine	182-189	thioredoxin 2	Arabidopsis thaliana	0-14
16272569-1	2005	A cyclic chimeric dodecapeptide (cCD) mimicking the conformation-specific domains of CCR5 and CXCR4 was prepared in which Gly-Asp links the amino and carboxyl termini of two combined pentapeptides (S169-G173 of CCR5; E179-R183 of CXCR4) derived from human immunodeficiency virus type-1 (HIV-1) coreceptors.	Glycine	122-125	chemokine (C-X-C motif) receptor 4	Mus musculus	94-99
34155371-2	2021	Thioredoxin h2 (Trx-h2)-a cytosolic redox protein identified as an interacting partner of CBF1-is normally anchored to cytoplasmic endomembranes through myristoylation at the second glycine residue5,6.	Glycine	182-189	C-repeat/DRE binding factor 1	Arabidopsis thaliana	90-94
16272569-1	2005	A cyclic chimeric dodecapeptide (cCD) mimicking the conformation-specific domains of CCR5 and CXCR4 was prepared in which Gly-Asp links the amino and carboxyl termini of two combined pentapeptides (S169-G173 of CCR5; E179-R183 of CXCR4) derived from human immunodeficiency virus type-1 (HIV-1) coreceptors.	Glycine	122-125	chemokine (C-X-C motif) receptor 4	Mus musculus	230-235
18258176-0	2008	Arginine and glycine stimulate creatine synthesis in creatine transporter 1-deficient lymphoblasts.	Glycine	13-20	solute carrier family 6 member 8	Homo sapiens	53-75
34163069-2	2021	In human haematological malignancies, recurrent chromosomal translocation of nucleoporin (NUP98 or NUP214) generates an aberrant chimera that invariably retains the nucleoporin IDR-tandemly dispersed repeats of phenylalanine and glycine residues1,2.	Glycine	229-236	ArfGAP with FG repeats 2	Homo sapiens	77-88
18342853-6	2008	We found a significant association of the allele Gly-637 (GGC) (p=0.00004, OR=27.30, CI=3.87-548.04) and the genotypes Asp-637/Gly-637 (p=0.01, OR=16.0, CI=2.19-631.21), Pro-661/Pro-661 (p=0.006, OR=11.30, CI=2.28-75.77) with HP.	Glycine	49-52	gamma-glutamylcyclotransferase	Homo sapiens	58-61
18342853-6	2008	We found a significant association of the allele Gly-637 (GGC) (p=0.00004, OR=27.30, CI=3.87-548.04) and the genotypes Asp-637/Gly-637 (p=0.01, OR=16.0, CI=2.19-631.21), Pro-661/Pro-661 (p=0.006, OR=11.30, CI=2.28-75.77) with HP.	Glycine	127-130	gamma-glutamylcyclotransferase	Homo sapiens	58-61
34163069-2	2021	In human haematological malignancies, recurrent chromosomal translocation of nucleoporin (NUP98 or NUP214) generates an aberrant chimera that invariably retains the nucleoporin IDR-tandemly dispersed repeats of phenylalanine and glycine residues1,2.	Glycine	229-236	ArfGAP with FG repeats 2	Homo sapiens	165-176
18262473-2	2008	Elements of the glycinergic phenotype include the membrane-bound glycine transporters (GLYT1 and GLYT2), which remove glycine from the synaptic cleft, and the vesicular inhibitory amino acid transporter (VIAAT or VGAT), which sequesters both glycine and GABA into synaptic vesicles.	Glycine	16-23	solute carrier family 6 member 5 S homeolog	Xenopus laevis	97-102
18262473-2	2008	Elements of the glycinergic phenotype include the membrane-bound glycine transporters (GLYT1 and GLYT2), which remove glycine from the synaptic cleft, and the vesicular inhibitory amino acid transporter (VIAAT or VGAT), which sequesters both glycine and GABA into synaptic vesicles.	Glycine	16-23	solute carrier family 32 member 1 S homeolog	Xenopus laevis	204-209
35500441-6	2022	In vitro assays revealed that EDEM3 can convert an asparagine-linked M9 glycan to M8 and M7 glycans in contrast to glycine-linked M9 glycan, and the activity is enhanced in the presence of ERp46, a known partner protein of EDEM3.	Glycine	115-122	thioredoxin domain containing 5	Homo sapiens	189-194
19099712-3	2008	Direct sequence analyses of genomic DNA have demonstrated that there is an identical single nucleotide substitution (c617G--&gt;A, R206H) in the glycine-serine (GS) activation domain of ACVR1 gene, responsible for all affected individuals reported so far.	Glycine	145-152	activin A receptor type 1	Homo sapiens	186-191
16039995-1	2005	Thioredoxin (TRX) is a 12-kDa redox (reduction/oxidation)-active protein that has a highly conserved site (-Cys-Gly-Pro-Cys-) and scavenges reactive oxygen species.	Glycine	112-115	thioredoxin 1	Mus musculus	0-11
16039995-1	2005	Thioredoxin (TRX) is a 12-kDa redox (reduction/oxidation)-active protein that has a highly conserved site (-Cys-Gly-Pro-Cys-) and scavenges reactive oxygen species.	Glycine	112-115	thioredoxin 1	Mus musculus	13-16
35500441-6	2022	In vitro assays revealed that EDEM3 can convert an asparagine-linked M9 glycan to M8 and M7 glycans in contrast to glycine-linked M9 glycan, and the activity is enhanced in the presence of ERp46, a known partner protein of EDEM3.	Glycine	115-122	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	223-228
18361930-1	2008	Two biallelic polymorphisms, previously described in the human intercellular adhesion molecule (ICAM)-1 gene at codon 241 (glycine [G] to arginine [R] substitution) and codon 469 (glutamic acid [E] to lysine [K] substitution) have been associated with a number of diseases including myocardial infarction, transplant rejection, and diabetes.	Glycine	123-130	intercellular adhesion molecule 1	Homo sapiens	63-103
18247306-5	2008	RESULTS: Upon bidirectional sequence analysis, a G--&gt;A transition at nucleotide 138 (c.138G&gt;A)in exon 2 of GJA8 was found, resulting in synonymous mutation of glycine (GGG) to glycine (GGA).	Glycine	165-172	gap junction protein alpha 8	Homo sapiens	113-117
35597930-5	2022	MFG-E8 is a secreted protein with NH2-terminal epidermal growth factor (EGF)-like domains, containing an Arg-Gly-Asp(RGD) sequence that binds alphavbeta3 and alphavbeta5 integrins, and COOH terminal domains C1 and C2, which can bind to lipid membrane with strong affinity.	Glycine	109-112	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	0-6
18247306-5	2008	RESULTS: Upon bidirectional sequence analysis, a G--&gt;A transition at nucleotide 138 (c.138G&gt;A)in exon 2 of GJA8 was found, resulting in synonymous mutation of glycine (GGG) to glycine (GGA).	Glycine	182-189	gap junction protein alpha 8	Homo sapiens	113-117
18081319-0	2008	Suppression of microtubule dynamic instability by the +TIP protein EB1 and its modulation by the CAP-Gly domain of p150glued.	Glycine	101-104	microtubule associated protein RP/EB family member 1	Homo sapiens	67-70
16141006-8	2005	By sequencing the CRYGS gene, a distinct 1619G-->T (AC068631) heterozygous missense mutation in exon 2 was identified, co-segregating with the disease phenotype in this family and resulting in a glycine (GGC) to valine residue (GTC) substitution in codon 18 (NP_060011).	Glycine	195-202	gamma-glutamylcyclotransferase	Homo sapiens	204-207
16002044-6	2005	Mutation of serine 180 or glycine 181 in CD44H reduced chondroitin sulfate addition and increased hyaluronan binding, indicating that serine 180 is the site for chondroitin sulfate addition in CD44H and that this negatively regulates hyaluronan binding.	Glycine	26-33	CD44 molecule (Indian blood group)	Homo sapiens	41-45
35213728-9	2022	Intriguingly, when all data were pooled, variations in CTX and PINP levels were positively correlated with fluctuations in proline and glycine concentrations (r>0.5 or 0.3<r<0.5, p<0.05).	Glycine	135-142	cytochrome P450 family 27 subfamily A member 1	Homo sapiens	55-58
16060660-1	2005	Mutations in the Kirsten ras (KRAS) gene are present in almost all pancreatic adenocarcinomas, and one common mutation is at codon 12: GGT (Gly) is transformed into GAT (Asp).	Glycine	140-143	KRAS proto-oncogene, GTPase	Homo sapiens	17-28
18046452-2	2008	We show that Mex67-Mtr2 through the same surface that recruits pre-60S particles interacts with the Nup84 complex, a structural module of the nuclear pore complex devoid of Phe-Gly domains.	Glycine	177-180	nuclear RNA export factor 1	Homo sapiens	13-18
17962328-0	2008	Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.	Glycine	14-21	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	84-88
16060660-1	2005	Mutations in the Kirsten ras (KRAS) gene are present in almost all pancreatic adenocarcinomas, and one common mutation is at codon 12: GGT (Gly) is transformed into GAT (Asp).	Glycine	140-143	KRAS proto-oncogene, GTPase	Homo sapiens	30-34
17962328-3	2008	We show that the potency of a variety of endogenous and synthetic glycine-site coagonists varies between recombinant NMDARs such that the highest potency is seen at NR2D-containing and the lowest at NR2A-containing NMDARs.	Glycine	66-73	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	199-203
35550508-3	2022	Integrative transcriptomic, metabolomic and functional data reveal that hyperactivation of the serine-glycine-one-carbon network is a metabolic hallmark inherent to CDK12-induced tumorigenesis.	Glycine	102-109	cyclin-dependent kinase 12	Mus musculus	165-170
17962328-6	2008	Glycine concentration-response curves for NMDARs containing NR2A subunits including the NR2D S1 region gave mean glycine EC(50) values similar to NR2A(WT)-containing NMDARs.	Glycine	0-7	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	60-64
17962328-7	2008	However, receptors containing NR2A subunits including the NR2D S2 region or both NR2D S1 and S2 regions gave glycine potencies similar to those seen in NR2D(WT)-containing NMDARs.	Glycine	109-116	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	30-34
17962328-8	2008	In particular, two residues in the S2 region of the NR2A subunit (Lys719 and Tyr735) when mutated to the corresponding residues found in the NR2D subunit influence glycine potency.	Glycine	164-171	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	52-56
18804700-7	2008	It removes excess AdoMet by using it for methylation of glycine.	Glycine	56-63	methionine adenosyltransferase I, alpha	Mus musculus	18-24
16060660-1	2005	Mutations in the Kirsten ras (KRAS) gene are present in almost all pancreatic adenocarcinomas, and one common mutation is at codon 12: GGT (Gly) is transformed into GAT (Asp).	Glycine	140-143	glycine-N-acyltransferase	Homo sapiens	165-168
16081002-1	2005	KCC2 is a neuron-specific Cl- transporter whose role in adult central neurons is to maintain low intracellular Cl- concentrations and, therefore, generate an inward-directed electrochemical gradient for Cl- needed for the hyperpolarizing responses to the inhibitory amino acids GABA and glycine.	Glycine	287-294	solute carrier family 12 member 5	Homo sapiens	0-4
16081002-5	2005	Considering that GABA and glycine are depolarizing during early postnatal development, it is conceivable that KCC2 is in place but inactive during early postnatal development in the CN and becomes active as inhibitory synaptogenesis proceeds.	Glycine	26-33	solute carrier family 12 member 5	Homo sapiens	110-114
17878166-9	2007	The Arg(26) in SCA3, replacing the Gly(26) in SCA1, is predicted to cause structural changes that result in a significantly reduced volume for the internal hydrophobic cavity in SCA3.	Glycine	35-38	ataxin 3	Homo sapiens	15-19
17878166-9	2007	The Arg(26) in SCA3, replacing the Gly(26) in SCA1, is predicted to cause structural changes that result in a significantly reduced volume for the internal hydrophobic cavity in SCA3.	Glycine	35-38	ataxin 3	Homo sapiens	178-182
35582490-13	2022	The improvement in isolate replication ability was most likely related to S654 to glycine (G) substitution in the basic protein (PB) 1 as well as to aspartic acid (D) 701 to asparagine (N) and arginine (R) 477 to G in PB2, glutamic acid (E) 204 to D and G239E in haemagglutinin and T135S in NA.	Glycine	82-89	polybromo 1	Sus scrofa	114-134
17929810-0	2007	Cross-strand coupling of a beta-hairpin peptide stabilized with an Aib-Gly turn studied using isotope-edited IR spectroscopy.	Glycine	71-74	ANIB1	Homo sapiens	67-70
17929810-1	2007	Isotope-edited IR spectroscopy was used to study a series of singly and doubly 13C=O-labeled beta-hairpin peptides stabilized by an Aib-Gly turn sequence.	Glycine	136-139	ANIB1	Homo sapiens	132-135
15968466-3	2005	The Na+-dependent (NHE3-sensitive) component of apical dipeptide ([14C] Gly-Sar) uptake was inhibited by the selective NHE inhibitors with the same order of potency observed for inhibition of apical 22Na+ uptake.	Glycine	72-75	solute carrier family 9 member A3	Homo sapiens	19-23
35267786-5	2022	Results showed a high quality of the extracted-elastin with the presence of a high amount of proline (6.55 +- 0.40%) and glycine (9.65 +- 0.44%), low amount of hydroxyproline (0.80 +- 0.32%), methionine (2.04 +- 0.05%), and histidine (1.81 +- 0.05%) together with calculated 0.56 isoleucine/leucine ratio.	Glycine	121-128	elastin	Bos taurus	47-54
16009141-4	2005	RESULTS: The activities of prolidase I and II against glycylproline and methionylproline were enhanced by glycine, L- and D-isoforms of alanine and serine and D-isoforms of valine, leucine and isoleucine.	Glycine	106-113	peptidase D	Homo sapiens	27-36
16009141-8	2005	CONCLUSION: The activities of prolidase I and II against various iminodipeptides were prominently enhanced by glycine, but the effect of L-valine differed between the two enzymes.	Glycine	110-117	peptidase D	Homo sapiens	30-39
17572636-1	2007	Individuals with fibrodysplasia ossificans progressiva are born with malformations of the great toes and develop a heterotopic skeleton during childhood because of an identical heterozygous mutation in the glycine-serine activation domain of ACVR1, a bone morphogenetic protein type I receptor.	Glycine	206-213	activin A receptor type 1	Homo sapiens	242-247
35136972-10	2022	RNA-Seq and verification showed that glycine regulated the ferroptosis pathway through increase S-adenosylmethionine (SAM) concentration and decrease the expression of GPX4 and FTH1 by promoting SAM-mediated GPX4 promoter methylation and reducing FTH1 expression in RA FLS.	Glycine	37-44	glutathione peroxidase 4	Mus musculus	168-172
35136972-10	2022	RNA-Seq and verification showed that glycine regulated the ferroptosis pathway through increase S-adenosylmethionine (SAM) concentration and decrease the expression of GPX4 and FTH1 by promoting SAM-mediated GPX4 promoter methylation and reducing FTH1 expression in RA FLS.	Glycine	37-44	glutathione peroxidase 4	Mus musculus	208-212
17886558-9	2007	Antibodies against integrin alphav or alphavbeta5 or arginine-glycine-aspartic acid-containing peptides, both of which block the vitronectin-glioma cell interactions, significantly reduced serum-induced cell migration, whereas blocking the interaction of glioma cells with fibronectin had no effect.	Glycine	62-69	vitronectin	Homo sapiens	129-140
15920735-2	2005	OPN contains the arginine-glycine-aspartic acid (RGD) moiety that has been shown to mediate cell adhesion through interactions with integrins.	Glycine	26-33	secreted phosphoprotein 1	Bos taurus	0-3
35136972-11	2022	CONCLUSIONS: In summary, we confirmed a decline in ferroptosis in RA and explored that glycine enhanced ferroptosis via SAM-mediated GPX4 promoter methylation and ferritin decrease.	Glycine	87-94	glutathione peroxidase 4	Mus musculus	133-137
15948949-11	2005	Glycine regulation was also found to be dependent on an intact SHM2 gene, which encodes cytoplasmic serine hydroxymethyltransferase.	Glycine	0-7	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	63-67
35016500-0	2022	Novel Peptide Motifs Containing Asp-Glu-Gly Target P2Y12 and Thromboxane A2 Receptors to Inhibit Platelet Aggregation and Thrombus Formation.	Glycine	40-43	purinergic receptor P2Y, G-protein coupled 12	Mus musculus	51-56
15948949-13	2005	A number of genes, including BAS1 were required for activation by glycine but only the SHM2 gene was required for repression in the absence of glycine.	Glycine	143-150	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	87-91
15948949-14	2005	We also showed that regulation of the SHM2 promoter by glycine requires Bas1p but not Bas2p or Gcn4p using a beta-galactosidase reporter.	Glycine	55-62	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	38-42
15948949-15	2005	The response of the promoter to glycine required an intact SHM2 gene but was restored in a shm2 strain by addition of formate to the medium.	Glycine	32-39	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	59-63
15948949-15	2005	The response of the promoter to glycine required an intact SHM2 gene but was restored in a shm2 strain by addition of formate to the medium.	Glycine	32-39	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	91-95
15985154-7	2005	Mutations of conserved glycines in human CD9 (Gly25 and Gly32 in TM1; Gly67 and Gly74 in TM2) caused aggregation of mutant proteins inside the cell.	Glycine	23-31	CD9 molecule	Homo sapiens	41-44
35187416-6	2022	Cys-528 in the elephant shark PR corresponds to Gly-722 in the human PR, which is essential for RU486 inhibition of the human PR.	Glycine	48-51	transmembrane protein 37	Homo sapiens	69-71
15985154-8	2005	Modeling of the TM1-TM2 interface in CD9, using a novel algorithm, predicts tight packing of conserved bulky residues against conserved Gly residues along the two helices.	Glycine	136-139	CD9 molecule	Homo sapiens	37-40
35187416-6	2022	Cys-528 in the elephant shark PR corresponds to Gly-722 in the human PR, which is essential for RU486 inhibition of the human PR.	Glycine	48-51	transmembrane protein 37	Homo sapiens	126-128
2516327-4	1989	Prevention of the metabolism of milacemide to glycine by pretreatment with MAO-B inhibitors not only prevents the memory-enhancing effects of the drug, but appears to have a deleterious effect on memory formation suggesting an action of the prodrug itself on the brain.	Glycine	46-53	monoamine oxidase B	Rattus norvegicus	75-80
15809046-2	2005	Belgrade rats have a glycine-to-arginine (G185R) mutation in DMT1, which affects its function.	Glycine	21-28	RoBo-1	Rattus norvegicus	61-65
15900495-6	2005	Most of the protein sequence features involved in binding ATP are conserved, with two exceptions: chicken TAP1 has a glycine in the switch region where other TAPs have glutamine or histidine, and both chicken TAP genes have serines in the C motif where mammalian TAP2 has an alanine.	Glycine	117-124	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	Gallus gallus	106-110
15900495-6	2005	Most of the protein sequence features involved in binding ATP are conserved, with two exceptions: chicken TAP1 has a glycine in the switch region where other TAPs have glutamine or histidine, and both chicken TAP genes have serines in the C motif where mammalian TAP2 has an alanine.	Glycine	117-124	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	Gallus gallus	106-109
15833348-3	2005	When the methionine-7 (Met-7) residue, which coordinates to the heme iron as an axial ligand, of the wild-type cytochrome b562 was replaced by an Ala or Gly residue, a water molecule bound to the heme iron and the electron transfer rate constants decreased to 1.3 x 10(-3) and 1.8 x 10(-3) cm s(-1), respectively.	Glycine	153-156	mitochondrially encoded cytochrome b	Homo sapiens	111-123
15864128-7	2005	Genetic analysis of ABCC2 identified a heterozygous mutation replacing a highly conserved arginine by glycine in the cytoplasmic part of the second membrane-spanning domain (position 412 of MRP2), a region associated with substrate affinity.	Glycine	102-109	ATP binding cassette subfamily C member 2	Homo sapiens	20-25
15864128-7	2005	Genetic analysis of ABCC2 identified a heterozygous mutation replacing a highly conserved arginine by glycine in the cytoplasmic part of the second membrane-spanning domain (position 412 of MRP2), a region associated with substrate affinity.	Glycine	102-109	ATP binding cassette subfamily C member 2	Homo sapiens	190-194
15853909-3	2005	The new DQB1 allele, DQB1*0314, was differed from DQB1*0304 only at codon 46 (GAG--&gt;GGG), corresponding to non-synonymous amino acid change (Glu--&gt;Gly).	Glycine	153-156	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	8-12
15853909-3	2005	The new DQB1 allele, DQB1*0314, was differed from DQB1*0304 only at codon 46 (GAG--&gt;GGG), corresponding to non-synonymous amino acid change (Glu--&gt;Gly).	Glycine	153-156	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	21-25
15853909-3	2005	The new DQB1 allele, DQB1*0314, was differed from DQB1*0304 only at codon 46 (GAG--&gt;GGG), corresponding to non-synonymous amino acid change (Glu--&gt;Gly).	Glycine	153-156	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	21-25
15781409-3	2005	[11C]Gly-Sar exhibited rapid initial uptake into kidneys with slow clearance from the medulla, consistent with uptake and retention of the radiotracer through the actions of PepT2.	Glycine	5-8	solute carrier family 15 (H+/peptide transporter), member 2	Mus musculus	174-179
15781409-5	2005	Involvement of PepT2 in reabsorption and delayed clearance of [11C]Gly-Sar was confirmed using the PepT2 knockout mouse, where rapid renal elimination of [11C]Gly-Sar and the absence of radioactivity in medulla were observed.	Glycine	67-70	solute carrier family 15 (H+/peptide transporter), member 2	Mus musculus	15-20
15781409-5	2005	Involvement of PepT2 in reabsorption and delayed clearance of [11C]Gly-Sar was confirmed using the PepT2 knockout mouse, where rapid renal elimination of [11C]Gly-Sar and the absence of radioactivity in medulla were observed.	Glycine	159-162	solute carrier family 15 (H+/peptide transporter), member 2	Mus musculus	15-20
15781409-6	2005	This study demonstrates using in vivo imaging technique that PepT2 is primarily responsible for renal tubular active reabsorption of Gly-Sar, and provides a new tool for studying tubular peptide reabsorption and clearance.	Glycine	133-136	solute carrier family 15 (H+/peptide transporter), member 2	Mus musculus	61-66
15735747-8	2005	Interestingly, an alpha(13) mutant where a conserved Gly was mutated to a Ser (G205S) retained its ability to bind to p115RhoGEF, induce p115RhoGEF recruitment to the PM, and activate Rho-dependent signaling, even though identical Gly to Ser mutations in other alpha disrupt their interaction with regulator of G-protein signaling (RGS) proteins.	Glycine	53-56	Rho guanine nucleotide exchange factor 1	Homo sapiens	118-128
15735747-8	2005	Interestingly, an alpha(13) mutant where a conserved Gly was mutated to a Ser (G205S) retained its ability to bind to p115RhoGEF, induce p115RhoGEF recruitment to the PM, and activate Rho-dependent signaling, even though identical Gly to Ser mutations in other alpha disrupt their interaction with regulator of G-protein signaling (RGS) proteins.	Glycine	53-56	Rho guanine nucleotide exchange factor 1	Homo sapiens	137-147
15660380-2	2005	Disease-causing mutations both in Nramp1 and Nramp2 occurring at the conserved two adjacent glycine residues located within the fourth transmembrane domain (TM4) suggest that TM4 may serve an important biological function.	Glycine	92-99	solute carrier family 11 member 1	Rattus norvegicus	34-40
15750346-1	2005	The role of residue C323 in catalysis by human glutamate dehydrogenase isozymes (hGDH1 and hGDH2) was examined by substituting Arg, Gly, Leu, Met, or Tyr at C323 by cassette mutagenesis using synthetic human GDH isozyme genes.	Glycine	132-135	glutamate dehydrogenase 2	Homo sapiens	91-96
15671159-4	2005	The atomic structure of AQP1 and amino acid sequence alignments of the mammalian aquaporins reveal two well conserved glycine residues: Gly-57 in transmembrane helix (TM) 2 and Gly-173 in TM5 reside at the contact point where the two helices cross in human AQP1.	Glycine	177-180	tropomyosin 3	Homo sapiens	188-191
16189623-3	2005	DDEB basically results from a glycine substitution mutation within the collagenous domain on one COL7A1 allele, while a combination of mutations such as premature stop codon, missense, and splice-site mutations on both alleles causes RDEB.	Glycine	30-37	collagen type VII alpha 1 chain	Homo sapiens	97-103
15922102-7	2005	We hypothesize, therefore, that subjects that are homozygous for Gly at amino acid 16 of the beta2AR have higher baseline blood pressure than Arg16 homozygotes due to beta2AR-mediated increases in ENaC activity in the kidney, caused, at least in part, by greater beta2AR density or enhanced beta2AR function of the Gly16 group.	Glycine	65-68	adrenoceptor beta 2	Homo sapiens	93-100
15953819-6	2005	P2Y2 receptors, via an RGD (Arg-Gly-Asp) motif in their first extracellular loop, bind to alphavbeta3/beta5 integrins, whereupon P2Y2 receptor activation stimulates integrin signaling pathways that regulate cytoskeletal reorganization and cell motility.	Glycine	32-35	purinergic receptor P2Y2	Homo sapiens	0-4
15953819-6	2005	P2Y2 receptors, via an RGD (Arg-Gly-Asp) motif in their first extracellular loop, bind to alphavbeta3/beta5 integrins, whereupon P2Y2 receptor activation stimulates integrin signaling pathways that regulate cytoskeletal reorganization and cell motility.	Glycine	32-35	purinergic receptor P2Y2	Homo sapiens	129-133
15610032-5	2004	The C-terminal of both human and porcine TGFBIp is truncated predominantly after the integrin binding sequence Arg(642)-Gly(643)-Asp(644) (RGD).	Glycine	120-123	transforming growth factor beta induced	Homo sapiens	41-47
15522200-2	2004	Here we describe that the central domain containing glycine-rich region in Sox4, named CD, is a pivotal pro-apoptotic domain to induce apoptotic cell death.	Glycine	52-59	SRY-box transcription factor 4	Homo sapiens	75-79
15498503-0	2004	Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor.	Glycine	92-99	gastrin releasing peptide	Homo sapiens	109-134
15555918-6	2004	Synaptic GlyRs were apposed to glycinergic boutons characterized by the expression of the vesicular and the plasma membrane transporters of glycine (VIAAT and GlyT2, respectively).	Glycine	31-38	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	159-164
15515020-5	2004	Many of the neurons in the dorsal expression domain that were positive for GABA markers at embryonic stages were also positive for GLYT2, suggesting that the cells might use both GABA and glycine, at least early in their development.	Glycine	188-195	solute carrier family 6 member 5	Danio rerio	131-136
15474473-2	2004	The substitution of Val-45 of CYP2D1 by glycine decreased the microsomal content, whereas the substitution of Gly-45 of CYP2D2 by valine increased.	Glycine	40-47	cytochrome P450, family 2, subfamily d, polypeptide 1	Rattus norvegicus	30-36
15543539-2	2004	The single Ser/Gly difference between CaCNT/19-20196 and CaCNT occurs at position 328 in putative TM 7, and corresponds to a Ser/Gly substitution previously shown to contribute to the contrasting pyrimidine and purine nucleoside selectivities of human (h) and rat (r) Na+-dependent CNT1 and CNT2.	Glycine	15-18	solute carrier family 28 member 1	Rattus norvegicus	282-286
15543539-2	2004	The single Ser/Gly difference between CaCNT/19-20196 and CaCNT occurs at position 328 in putative TM 7, and corresponds to a Ser/Gly substitution previously shown to contribute to the contrasting pyrimidine and purine nucleoside selectivities of human (h) and rat (r) Na+-dependent CNT1 and CNT2.	Glycine	129-132	solute carrier family 28 member 1	Rattus norvegicus	282-286
15471493-2	2004	Variable-temperature NMR and examination of the glycine derivative shows that the isomers observed are due to t-Boc rotation.	Glycine	48-55	BOC cell adhesion associated, oncogene regulated	Homo sapiens	112-115
15334382-8	2004	Our findings suggest that the beta(2)-AR Arg(16)-Gly genotype influences T-C and LDL-C levels in an age-specific manner, that it may interact with beta(3)-AR Trp(64)-Arg genotypes to influence longitudinal T-C and LDL-C profiles, and that the effect of combined beta(2)/beta(3)-AR genotypes on T-C and LDL-C profiles may differ among race/sex groups.	Glycine	49-52	adrenoceptor beta 2	Homo sapiens	30-40
15304324-3	2004	In the present study, however, we found that rat PU.1 has Gly at position 41.	Glycine	58-61	Spi-1 proto-oncogene	Rattus norvegicus	49-53
15158481-6	2004	Insertion of a portion of the NST-N/OFQ precursor (Glu-Gln-Lys-Gln-Leu-Gln-Lys-Arg-Phe-Gly-Gly-Phe-Tyr-Gly) in Vluc-EYFP makes the fusion protein cleavable at Lys-Arg in NG108-15 cells, and proprotein convertase 1 enhances this digestion.	Glycine	87-90	prepronociceptin	Mus musculus	34-39
15158481-6	2004	Insertion of a portion of the NST-N/OFQ precursor (Glu-Gln-Lys-Gln-Leu-Gln-Lys-Arg-Phe-Gly-Gly-Phe-Tyr-Gly) in Vluc-EYFP makes the fusion protein cleavable at Lys-Arg in NG108-15 cells, and proprotein convertase 1 enhances this digestion.	Glycine	87-90	proprotein convertase subtilisin/kexin type 1	Mus musculus	190-213
15158481-6	2004	Insertion of a portion of the NST-N/OFQ precursor (Glu-Gln-Lys-Gln-Leu-Gln-Lys-Arg-Phe-Gly-Gly-Phe-Tyr-Gly) in Vluc-EYFP makes the fusion protein cleavable at Lys-Arg in NG108-15 cells, and proprotein convertase 1 enhances this digestion.	Glycine	91-94	prepronociceptin	Mus musculus	34-39
15158481-6	2004	Insertion of a portion of the NST-N/OFQ precursor (Glu-Gln-Lys-Gln-Leu-Gln-Lys-Arg-Phe-Gly-Gly-Phe-Tyr-Gly) in Vluc-EYFP makes the fusion protein cleavable at Lys-Arg in NG108-15 cells, and proprotein convertase 1 enhances this digestion.	Glycine	91-94	proprotein convertase subtilisin/kexin type 1	Mus musculus	190-213
15158481-6	2004	Insertion of a portion of the NST-N/OFQ precursor (Glu-Gln-Lys-Gln-Leu-Gln-Lys-Arg-Phe-Gly-Gly-Phe-Tyr-Gly) in Vluc-EYFP makes the fusion protein cleavable at Lys-Arg in NG108-15 cells, and proprotein convertase 1 enhances this digestion.	Glycine	91-94	prepronociceptin	Mus musculus	34-39
15158481-6	2004	Insertion of a portion of the NST-N/OFQ precursor (Glu-Gln-Lys-Gln-Leu-Gln-Lys-Arg-Phe-Gly-Gly-Phe-Tyr-Gly) in Vluc-EYFP makes the fusion protein cleavable at Lys-Arg in NG108-15 cells, and proprotein convertase 1 enhances this digestion.	Glycine	91-94	proprotein convertase subtilisin/kexin type 1	Mus musculus	190-213
15060063-0	2004	Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester.	Glycine	0-7	scavenger receptor class B member 1	Homo sapiens	56-61
15256252-3	2004	Rat and mouse SMGC have deduced molecular weights of 67.8 and 74.4 kDa, respectively, are 37% Ser+Gly+Thr, and contain tandem repeats of between 8 and 60 amino acids.	Glycine	98-101	submandibular gland protein C	Mus musculus	14-18
15481680-2	2004	In this study the molecular basis was characterized: ESD*5, arising from ESD*1, has a G to A transition, resulting in Gly257(GGT) --&gt; Asp(GAT); and ESD*7, originating from ESD*2, has an A to G transition, resulting in Asp231(GAT) --&gt; Gly(GGT).	Glycine	118-121	glycine-N-acyltransferase	Homo sapiens	141-144
15031290-2	2004	The GLYT1 subtypes of glycine transporters (GLYTs) are responsible for regulation of glycine at excitatory synapses, whereas a combination of GLYT1 and GLYT2 subtypes of glycine transporters are used at inhibitory glycinergic synapses.	Glycine	22-29	solute carrier family 6 member 5 S homeolog	Xenopus laevis	152-157
15148339-1	2004	The Epstein-Barr virus (EBV) nuclear antigen (EBNA)1 contains a glycine-alanine repeat (GAr) domain that appears to protect the antigen from proteasomal breakdown and, as measured in cytotoxicity assays, from major histocompatibility complex (MHC) class I-restricted presentation to CD8+ T cells.	Glycine	64-71	CD8a molecule	Homo sapiens	283-286
15095410-2	2004	Our laboratory previously showed that the CSVTCG (cys-ser-val-thr-cys-gly) sequence of TSP-1 functioned as a tumor cell adhesion domain and CSVTCG peptides as well as an anti-peptide antibody possessed anti-metastatic activity in a murine model of lung metastasis.	Glycine	70-73	thrombospondin 1	Mus musculus	87-92
15113589-0	2004	The G2028R glycine substitution mutation in COL7A1 leads to marked inter-familiar clinical heterogeneity in dominant dystrophic epidermolysis bullosa.	Glycine	11-18	collagen type VII alpha 1 chain	Homo sapiens	44-50
15113589-1	2004	BACKGROUND: Glycine substitution mutations in COL7A1 not only cause dominant dystrophic epidermolysis bullosa (DDEB), but can also be silent mutations which lead to recessive dystrophic epidermolysis bullosa (RDEB) in combination with additional mutations in the other allele.	Glycine	12-19	collagen type VII alpha 1 chain	Homo sapiens	46-52
15113589-9	2004	CONCLUSION: This paper has demonstrated for the first time that identical COL7A1 glycine substitutions can cause remarkably heterogeneous clinical phenotypes extending from simple toe nail dystrophy without skin fragility to typical DDEB and EB pruriginosa.	Glycine	81-88	collagen type VII alpha 1 chain	Homo sapiens	74-80
14715656-8	2004	Both ADAMTS-4 and ADAMTS-5 cleaved alpha(2)M at Met(690)/Gly(691), representing a novel proteinase cleavage site within alpha(2)M and a novel site of cleavage for ADAMTS-4 and ADAMTS-5.	Glycine	57-60	ADAM metallopeptidase with thrombospondin type 1 motif 5	Homo sapiens	18-26
14688030-8	2004	Analysis of the K-ras gene revealed mutations in 82% (9/11) of carcinomas; all had specific G --&gt; T transversions (Gly --&gt; Val) at codons 10 or 12.	Glycine	118-121	KRAS proto-oncogene, GTPase	Homo sapiens	16-21
15069780-1	2004	It has been suggested that the Arg 16/Gly 16 allele at codon 16 of beta 2-adrenoceptor polymorphism plays a role in down-regulating the stimulus of bronchodilatation caused by beta 2-agonists.	Glycine	38-41	adrenoceptor beta 2	Homo sapiens	67-86
14672656-3	2004	This glycine residue, at the strand/loop junction of beta3/loop3, is found in U1A RBD1, and in most RBD domains, suggesting it has a specific role in modulation of RNA binding.	Glycine	5-12	small nuclear ribonucleoprotein polypeptide A	Homo sapiens	78-81
14962794-8	2004	Arginine/glycine (RG)-rich domains in components of the SMN complex interact with Sm, like-Sm (LSm), fibrillarin, RNA helicase A (Gu), and coilin proteins, all of which are antigen targets in a variety of diseases.	Glycine	9-16	fibrillarin	Homo sapiens	101-112
14693408-0	2004	Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients.	Glycine	9-12	adrenoceptor beta 2	Homo sapiens	53-78
14693408-0	2004	Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients.	Glycine	13-16	adrenoceptor beta 2	Homo sapiens	53-78
14992262-3	2004	In particular, intracellular chloride activity and hence the neuronal response to GABA and glycine appears to be determined by a balance between chloride efflux and influx through KCC2 and the Na+-K+-2Cl- cotransporter NKCC1, respectively.	Glycine	91-98	solute carrier family 12 member 5	Homo sapiens	180-184
15207356-7	2004	These data provide evidence that the observed increased in extracellular citrulline is a consequence of positive modulation of NMDA-R, secondary to increased extracellular glycine and support a protective role for GlyT-1 against fluctuations in extracellular glycine uptake at glutamatergic synapses in the dorsal spinal cord.	Glycine	259-266	solute carrier family 6 member 9	Rattus norvegicus	214-220
12951368-1	2003	Bile acid CoA:amino acid N-acyltransferase (BAT) is responsible for the amidation of bile acids with the amino acids taurine and glycine.	Glycine	129-136	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	44-47
12951368-4	2003	Similar to hBAT, expressed rBAT was capable of forming both taurine and glycine conjugates with cholyl-CoA.	Glycine	72-79	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	27-31
12949144-7	2003	In both species, the isopeptide bond is formed between lysine 118 of the actin and the C-terminal glycine 76 of ubiquitin.	Glycine	98-105	Ribosomal protein S27A	Drosophila melanogaster	112-121
14504280-5	2003	The structure of the Mtr2-Mex67 NTF2-like domain complex, which overall is similar to those of the human and Saccharomyces cerevisiae homologs, unveils three putative Phe-Gly repeat binding sites, of which one contributes to the heterodimer interface.	Glycine	171-174	nuclear RNA export factor 1	Homo sapiens	26-31
14529265-5	2003	The interaction of I-BABP with nine physiologically relevant derivatives of cholic acid, chenodeoxycholic acid, and deoxycholic acid in their conjugated (glycine and taurine) and unconjugated forms was monitored by isothermal titration calorimetry.	Glycine	154-161	fatty acid binding protein 6	Homo sapiens	19-25
14756420-6	2003	The Cys-129 of HSRLC corresponds to the critical Gly-117 of scallop RLC that is essential for its regulatory function.	Glycine	49-52	integrin subunit alpha 9	Homo sapiens	17-20
12941372-1	2003	In the central nervous system, re-uptake of the neurotransmitter glycine is mediated by two different glycine transporters, GlyT1 and GlyT2.	Glycine	65-72	solute carrier family 6 member 9	Rattus norvegicus	124-129
12941372-2	2003	GlyT2 is found in brainstem and spinal cord, whereas GlyT1 is expressed in rat forebrain regions where it is responsible for most glycine transport activity.	Glycine	130-137	solute carrier family 6 member 9	Rattus norvegicus	53-58
12947056-6	2003	K-ras codon 13 mutations (all with G-A nucleotide transitions resulting in Gly&gt;Asp substitution) and single activating mutations in any of the ras genes were also independent predictors of poor survival in differentiated thyroid carcinomas (P =.027 and P =.007, respectively).	Glycine	75-78	KRAS proto-oncogene, GTPase	Homo sapiens	0-5
12921997-6	2003	Additionally, a second viral protease, 2A(pro), also cleaves TBP at a tyrosine-glycine bond.	Glycine	79-86	TATA-box binding protein	Homo sapiens	61-64
12882924-3	2003	Vesicular inhibitory amino acid transporter (VIAAT), which is responsible for the storage of GABA and glycine in neuronal synaptic vesicles, is believed to be responsible for the storage and secretion of GABA in beta-cells.	Glycine	102-109	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	0-43
12882924-3	2003	Vesicular inhibitory amino acid transporter (VIAAT), which is responsible for the storage of GABA and glycine in neuronal synaptic vesicles, is believed to be responsible for the storage and secretion of GABA in beta-cells.	Glycine	102-109	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	45-50
12851728-6	2003	We identified a previously unreported GGT right curved arrow GAT transition at codon 451 in exon 3, resulting in a glycine to asparagine substitution in one POAG patient.	Glycine	115-122	glycine-N-acyltransferase	Homo sapiens	61-64
12721289-5	2003	Inhibition of the integrin/Src system by the RGD motif-containing peptide or PP-2 also prevented the inhibition of proteolysis and the decrease in autophagic vacuole volume, which is otherwise observed in response to hypoosmotic or glutamine/glycine-induced hepatocyte swelling.	Glycine	242-249	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	27-30
12823310-0	2003	A new glycine substitution mutation in the COL7A1 gene in a Chinese family with dominant dystrophic epidermolysis bullosa.	Glycine	6-13	collagen type VII alpha 1 chain	Homo sapiens	43-49
12823310-3	2003	In this study, we identified a Chinese family with a four-generation pedigree of DDEB, in whom a novel glycine substitution mutation in COL7A1 was demonstrated.	Glycine	103-110	collagen type VII alpha 1 chain	Homo sapiens	136-142
12823310-4	2003	A heterozygous nucleotide G--&gt;A transition at position 6208 in exon 74 of COL7A1 was detected, which resulted in a glycine to arginine substitution (G2070R) in the triple-helical domain of type VII collagen.	Glycine	118-125	collagen type VII alpha 1 chain	Homo sapiens	77-83
12684517-12	2003	Localization of SNAT1 to certain dopaminergic neurons of the substantia nigra and cholinergic motoneurons suggests that SNAT1 may play additional specialized roles, providing metabolic fuel (via alpha-ketoglutarate) or precursors (cysteine, glycine) for glutathione synthesis.	Glycine	241-248	solute carrier family 38 member 1 L homeolog	Xenopus laevis	16-21
12684517-12	2003	Localization of SNAT1 to certain dopaminergic neurons of the substantia nigra and cholinergic motoneurons suggests that SNAT1 may play additional specialized roles, providing metabolic fuel (via alpha-ketoglutarate) or precursors (cysteine, glycine) for glutathione synthesis.	Glycine	241-248	solute carrier family 38 member 1 L homeolog	Xenopus laevis	120-125
12642591-5	2003	Two triple-helical peptide (THP) models of the MMP-9 cleavage site in type V collagen, alpha1(V)436-450 THP and alpha1(V)436-447 fTHP, were hydrolyzed by MMP-2 and MMP-9 at the Gly-Val bond, analogous to the bond cleaved by MMP-9 in the corresponding native collagen.	Glycine	177-180	matrix metallopeptidase 9	Homo sapiens	47-52
12605599-1	2003	In a previous study we showed, by transient expression studies in COS-1 cells, that the C-terminal domain of rat intestinal membrane mucin Muc3 was cleaved between glycine and serine within a GSIVV (one-letter) amino acid sequence during its residence in the endoplasmic reticulum.	Glycine	164-171	solute carrier family 13 member 2	Rattus norvegicus	133-138
12605599-1	2003	In a previous study we showed, by transient expression studies in COS-1 cells, that the C-terminal domain of rat intestinal membrane mucin Muc3 was cleaved between glycine and serine within a GSIVV (one-letter) amino acid sequence during its residence in the endoplasmic reticulum.	Glycine	164-171	mucin 3	Rattus norvegicus	139-143
12473658-3	2003	GATE-16 contains a ubiquitin fold subdomain, which is terminated at the carboxyl end by an additional amino acid after a conserved glycine residue.	Glycine	131-138	GABA type A receptor associated protein like 2	Homo sapiens	0-7
12473658-4	2003	In the present study we tested whether the COOH terminus of GATE-16 undergoes post-translational cleavage by a protease which exposes the glycine 116 residue.	Glycine	138-145	GABA type A receptor associated protein like 2	Homo sapiens	60-67
12473658-6	2003	We show that GATE-16 undergoes COOH-terminal cleavage both in vivo and in vitro, only when the conserved glycine 116 is present.	Glycine	105-112	GABA type A receptor associated protein like 2	Homo sapiens	13-20
12667480-0	2003	Mechanisms of inhibition of phenylalanine ammonia-lyase by phenol inhibitors and phenol/glycine synergistic inhibitors.	Glycine	88-95	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	28-55
12562756-8	2003	Covalent attachment of myristate to the N-terminal Gly of Sip2p is essential for normal cellular life span.	Glycine	51-54	Sip2p	Saccharomyces cerevisiae S288C	58-63
12646261-1	2003	The C-terminal alpha-amide moiety of most peptide hormones arises by the posttranslational cleavage of a glycine-extended precursor in a reaction catalyzed by bifunctional peptidylglycine alpha-amidating monooxygenase (PAM).	Glycine	105-112	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	172-217
12646261-1	2003	The C-terminal alpha-amide moiety of most peptide hormones arises by the posttranslational cleavage of a glycine-extended precursor in a reaction catalyzed by bifunctional peptidylglycine alpha-amidating monooxygenase (PAM).	Glycine	105-112	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	219-222
12646261-2	2003	Glutathione and the S-alkylated glutathiones have a C-terminal glycine and are, thus, potential substrates for PAM.	Glycine	63-70	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	111-114
12392447-1	2003	Serine hydroxymethyltransferase (SHMT), a pyridoxal 5"-phosphate (PLP)-dependent enzyme, catalyses the transfer of the hydroxymethyl group from serine to tetrahydrofolate to yield glycine and N (5), N (10)-methylenetetrahydrofolate.	Glycine	180-187	serine hydroxymethyltransferase, cytosolic	Ovis aries	0-31
12612889-7	2003	Molecular genetic analysis revealed Ki-ras gene mutations at codons 13 (GGC(gly) to AGC(ser)) and 15 (GGC(gly) to AGC(ser)) on the same allele.	Glycine	76-79	KRAS proto-oncogene, GTPase	Homo sapiens	36-42
12612889-7	2003	Molecular genetic analysis revealed Ki-ras gene mutations at codons 13 (GGC(gly) to AGC(ser)) and 15 (GGC(gly) to AGC(ser)) on the same allele.	Glycine	106-109	KRAS proto-oncogene, GTPase	Homo sapiens	36-42
12574447-4	2003	Extracellular glycine near NMDA-R is regulated effectively by a glial glycine transporter (GlyT1).	Glycine	14-21	solute carrier family 6 member 9	Rattus norvegicus	91-96
12574447-10	2003	These data suggest that direct GlyB site stimulation by D-serine, or blockade of GLYT1 to elevate endogenous glycine to act on unsaturated GlyB sites on NMDA-Rs, potentiated NMDA-R-mediated firing responses in rat PFC.	Glycine	109-116	solute carrier family 6 member 9	Rattus norvegicus	81-86
12574447-11	2003	Hence, blockade of GlyT1 to elevate glycine near the NMDA-R may activate hypofunctional NMDA-R, which has been implicated to play a critical role in the pathophysiology of schizophrenia.	Glycine	36-43	solute carrier family 6 member 9	Rattus norvegicus	19-24
12507496-3	2003	The C-terminal Phe(117) of proGATE-16 and the C-terminal Leu(117) of proGABARAP are post-translationally cleaved to expose an essential Gly(116) within GATE-16 and GABARAP, with the products designated GATE-16-I and GABARAP-I, respectively.	Glycine	136-139	GABA type A receptor associated protein like 2	Homo sapiens	30-37
12507496-3	2003	The C-terminal Phe(117) of proGATE-16 and the C-terminal Leu(117) of proGABARAP are post-translationally cleaved to expose an essential Gly(116) within GATE-16 and GABARAP, with the products designated GATE-16-I and GABARAP-I, respectively.	Glycine	136-139	GABA type A receptor associated protein like 2	Homo sapiens	152-159
12507496-4	2003	The Gly(116) within GATE-16 and GABARAP are essential for further formation of the intermediates between them and Apg7p(C572S) and Apg3p(C264S).	Glycine	4-7	GABA type A receptor associated protein like 2	Homo sapiens	20-27
12507496-4	2003	The Gly(116) within GATE-16 and GABARAP are essential for further formation of the intermediates between them and Apg7p(C572S) and Apg3p(C264S).	Glycine	4-7	autophagy related 3	Homo sapiens	131-136
12414796-1	2003	In human glutathione transferase P1-1 (hGSTP1-1) position 146 is occupied by a glycine residue, which is located in a bend of a long loop that together with the alpha6-helix forms a substructure (GST motif II) maintained in all soluble GSTs.	Glycine	79-86	crystallin gamma F, pseudogene	Homo sapiens	33-37
12480547-3	2003	In this study, we determined the structure of the peptide involving the residues from Gly 2 to Gly 34 of pig gastric H(+)/K(+)-ATPase and investigated the tyrosine phosphorylation-induced conformational change using CD and NMR experiments.	Glycine	86-89	ATPase H+/K+ transporting subunit alpha	Sus scrofa	117-133
12480547-3	2003	In this study, we determined the structure of the peptide involving the residues from Gly 2 to Gly 34 of pig gastric H(+)/K(+)-ATPase and investigated the tyrosine phosphorylation-induced conformational change using CD and NMR experiments.	Glycine	95-98	ATPase H+/K+ transporting subunit alpha	Sus scrofa	117-133
12509629-5	2003	The arginine-glycine-rich domain in hnRNP A2 was found to be the reaction site, and the methylation of hnRNP A2 by PRMT1 (protein arginine methyltransferase 1) was increased by anti-DNA.	Glycine	13-20	protein arginine methyltransferase 1	Homo sapiens	115-120
12509629-5	2003	The arginine-glycine-rich domain in hnRNP A2 was found to be the reaction site, and the methylation of hnRNP A2 by PRMT1 (protein arginine methyltransferase 1) was increased by anti-DNA.	Glycine	13-20	protein arginine methyltransferase 1	Homo sapiens	122-158
12359730-4	2002	The high glycine-tyrosine genes described here appear to represent the complete set of this type of KAP genes present in the human genome.	Glycine	9-16	cyclin dependent kinase inhibitor 3	Homo sapiens	100-103
12359730-5	2002	Both systematic cDNA isolation studies from an arrayed scalp cDNA library and in situ hybridization expression studies of all of the KAP genes identified in the 21q22.1 region revealed varying degrees and regions of expression of 11 members of the high tyrosine-glycine genes and 6 members of the high sulfur KAP genes in the hair forming compartment.	Glycine	262-269	cyclin dependent kinase inhibitor 3	Homo sapiens	133-136
12359720-6	2002	Grg1-S has highest homology with the TLE family of large Groucho proteins but features only the amino-terminal Q and glycine- and proline-rich domains typical of the Groucho/AES subfamily.	Glycine	117-124	TLE family member 1, transcriptional corepressor	Homo sapiens	0-4
12438634-9	2002	Processing after the C-terminal glycine residue of GABA(A)-RAP and GATE-16 by cellular proteases is essential for covalent attachment to target molecules.	Glycine	32-39	GABA type A receptor associated protein like 2	Homo sapiens	67-74
12602503-5	2002	Expression of Glyt-1 mRNA, studied by reverse transcriptase-polymerase chain reaction, was significantly decreased in the brain at coma stages of encephalopathy (to approximately 50% of control) concomitant with a significant threefold increase of extracellular glycine, measured by in vivo cerebral microdialysis.	Glycine	262-269	solute carrier family 6 member 9	Rattus norvegicus	14-20
12602503-6	2002	These findings suggest that loss of expression of the Glyt-1 transporter may cause an impairment of regulation of glycine concentration at synaptic level and contribute to an overactivation of the NMDA receptor in ALF.	Glycine	114-121	solute carrier family 6 member 9	Rattus norvegicus	54-60
12466543-0	2002	Methylation of Xenopus CIRP2 regulates its arginine- and glycine-rich region-mediated nucleocytoplasmic distribution.	Glycine	57-64	cold inducible RNA binding protein S homeolog	Xenopus laevis	23-28
12466543-4	2002	We found that an arginine- and glycine-rich region of xCIRP2, termed the RG4 domain, was a target of xPRMT1 for methylation in vitro.	Glycine	31-38	cold inducible RNA binding protein S homeolog	Xenopus laevis	54-60
12466543-4	2002	We found that an arginine- and glycine-rich region of xCIRP2, termed the RG4 domain, was a target of xPRMT1 for methylation in vitro.	Glycine	31-38	protein arginine methyltransferase 1 S homeolog	Xenopus laevis	101-107
12409231-6	2002	An unintended additional modification of secretin in synthesizing this probe was the elimination of Gly(4).	Glycine	100-103	secretin	Homo sapiens	41-49
12513909-7	2002	Three-dimensional models of IL-22 and IL-10 receptor complexes suggest two receptor residues (Gly-44 and Arg-96) are largely responsible for the marked differences in ligand affinity observed for sIL-10R1 and sIL-22R vs. sIL-10R2.	Glycine	94-97	interleukin 22	Homo sapiens	28-33
12513909-7	2002	Three-dimensional models of IL-22 and IL-10 receptor complexes suggest two receptor residues (Gly-44 and Arg-96) are largely responsible for the marked differences in ligand affinity observed for sIL-10R1 and sIL-22R vs. sIL-10R2.	Glycine	94-97	interleukin 10	Homo sapiens	38-43
12082110-2	2002	VN also interacts with two-chain high molecular weight kininogen (HKa), particularly its His-Gly-Lys-rich domain 5, and both HKa and PAI-1 are antiadhesive factors that have been shown to compete for binding to VN.	Glycine	93-96	vitronectin	Homo sapiens	0-2
12367623-6	2002	Phorbol ester 12,13-dibutyrate (PDBu, 1 microM), an activator of PKC, also depressed glycine-induced currents.	Glycine	85-92	protein kinase C, gamma	Rattus norvegicus	65-68
12367623-8	2002	Chelerythrine also attenuated the ethanol-induced depression of glycine-induced currents and its time-dependent decay, thus confirming our previous evidence that PKC mediates, at least in part, the decay of the depressant effect of ethanol on glycine-induced currents of VTA neurons.	Glycine	64-71	protein kinase C, gamma	Rattus norvegicus	162-165
12367623-8	2002	Chelerythrine also attenuated the ethanol-induced depression of glycine-induced currents and its time-dependent decay, thus confirming our previous evidence that PKC mediates, at least in part, the decay of the depressant effect of ethanol on glycine-induced currents of VTA neurons.	Glycine	243-250	protein kinase C, gamma	Rattus norvegicus	162-165
12065586-7	2002	The amino acid sequence of Gemin7 does not contain any recognizable motifs with the exception of several arginine and glycine repeats that are necessary for its interaction with SMN.	Glycine	118-125	gem nuclear organelle associated protein 7	Homo sapiens	27-33
12144698-2	2002	A comparison of cDNA sequences of individual insects from susceptible and resistant strains, coupled with an enzyme inhibition assay with omethoate, indicated a novel glycine-serine substitution (G488S), at an amino acid residue which is highly conserved across species (G396 of Torpedocalifornica AChE), as a likely cause of AChE insensitivity.	Glycine	167-174	acetylcholinesterase	Bactrocera oleae	298-302
12144698-2	2002	A comparison of cDNA sequences of individual insects from susceptible and resistant strains, coupled with an enzyme inhibition assay with omethoate, indicated a novel glycine-serine substitution (G488S), at an amino acid residue which is highly conserved across species (G396 of Torpedocalifornica AChE), as a likely cause of AChE insensitivity.	Glycine	167-174	acetylcholinesterase	Bactrocera oleae	326-330
12093444-12	2002	The blood CD4(+):CD8(+) ratio was significantly higher in the Arg group than in the Gly group at 24 h after CLP.	Glycine	84-87	Cd4 molecule	Rattus norvegicus	10-13
11970955-2	2002	HKa and particularly its His-Gly-Lys-rich domain 5 have been previously reported to exert anti-adhesive properties by binding to the extracellular matrix protein vitronectin (VN).	Glycine	29-32	vitronectin	Homo sapiens	162-173
11970955-2	2002	HKa and particularly its His-Gly-Lys-rich domain 5 have been previously reported to exert anti-adhesive properties by binding to the extracellular matrix protein vitronectin (VN).	Glycine	29-32	vitronectin	Homo sapiens	175-177
11959859-4	2002	Both mPAT1 and mPAT2 induced a pH-dependent electrogenic transport activity for small amino acids (glycine, alanine, and proline) that is altered by membrane potential.	Glycine	99-106	solute carrier family 36 (proton/amino acid symporter), member 1	Mus musculus	5-10
12059197-0	2002	Observation of the glycines in elastin using (13)C and (15)N solid-state NMR spectroscopy and isotopic labeling.	Glycine	19-27	elastin	Homo sapiens	31-38
12059197-1	2002	We report the solid-state 13C and 15N NMR of insoluble elastin which has been synthesized in vitro with isotopically enriched glycine.	Glycine	126-133	elastin	Homo sapiens	55-62
12403170-3	2002	In this work, we have characterised the patterns of nucleotide variation for gene regions containing two Gly and one Gln-Ala repeat in another D. melanogaster song gene, no-on-transient A, in D. virilis group species.	Glycine	105-108	no on or off transient A	Drosophila melanogaster	170-187
12513788-2	2002	Amplified cDNA of mDHFR and GFP segmented from their plasmid separately were linked by PCR with the aminoacetic acid linker.	Glycine	100-116	dihydrofolate reductase	Mus musculus	18-23
12009900-3	2002	In this study, analogues of Ac-Arg(6)-cyclo(S-S)(Cys(7)-Met(8)-Leu(9)-Gly(10)-Arg(11)-Val(12)-Tyr(13)-Arg(14)-Pro(15)-Cys(16))-NH(2), a high affinity but nonselective agonist at hMCH-1R and hMCH-2R, were prepared and tested in binding and functional assays on cells expressing these receptors.	Glycine	70-73	CD7 molecule	Homo sapiens	63-68
11986213-5	2002	DNA sequence analysis showed a heterozygous mutation of GGC (Gly)-->GAC (Asp) at codon 309 of the gamma chain gene.	Glycine	61-64	gamma-glutamylcyclotransferase	Homo sapiens	56-59
11993999-2	2002	Here the equivalent residue, Phe(282), in the beta(2)-AR was evaluated by mutation to glycine, asparagine, alanine, or leucine.	Glycine	86-93	adrenoceptor beta 2	Homo sapiens	46-56
11959905-8	2002	This glycine in P-loop A of AtHKT1 and HKT1 can be modeled as the first glycine of the K(+) channel selectivity filter GYG motif.	Glycine	5-12	cation transporter HKT1	Triticum aestivum	30-34
11959905-8	2002	This glycine in P-loop A of AtHKT1 and HKT1 can be modeled as the first glycine of the K(+) channel selectivity filter GYG motif.	Glycine	72-79	cation transporter HKT1	Triticum aestivum	30-34
11952795-8	2002	In the present study, we demonstrate that a fusion protein comprising CLC covalently coupled through a glycine/serine linker to sCNTFR (CC-FP) is efficiently secreted from transfected mammalian cells.	Glycine	103-110	Charcot-Leyden crystal galectin	Homo sapiens	70-73
11835157-6	2002	We used the Hoffman degradation reaction to convert the amide groups of acrylamide to amine groups, and then we used ethylene glycol diglycidyl ether to attach biomolecules of interest inside the holes: secreted protein acidic and rich in cysteine (SPARC) peptide Lys-Gly-His-Lys (KGHK; angiogenic), thrombospondin-2 (TSP; antiangiogenic), or albumin (rat; neutral).	Glycine	268-271	secreted protein acidic and cysteine rich	Rattus norvegicus	203-247
11883939-7	2002	The Ca(2+)-dependent fluorescence change of ALG-2 in the presence of the hydrophobicity fluorescent probe 2-p-toluidinylnaphthalene-6-sulfonate (TNS) was inhibited by mixing with GST-AnxN, suggesting that the Pro/Gly/Tyr/Ala-rich hydrophobic region in AnxN masked the Ca(2+)-dependently exposed hydrophobic surface of ALG-2.	Glycine	213-216	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	44-49
11756407-5	2002	The replacement of Gly(107), a residue close to the binding site, by cysteine (as in GlmS and Xenopus GKRP) resulted in a protein that had 20 times more affinity for Fru-6-P and 30 times less affinity for Fru-1-P.	Glycine	19-22	glucokinase regulator L homeolog	Xenopus laevis	102-106
12000196-4	2002	This paper deals with a point mutation in exon 2 position 47 of the TTR gene, encoding the substitution of glycine with glutamate.	Glycine	107-114	transthyretin	Homo sapiens	68-71
11861317-7	2002	Whereas PS potentiated NMDA-, glutamate-, and glycine-induced currents of NR1/NR2A and NR1/NR2B receptors, it was inhibitory at NR1/NR2C and NR1/NR2D receptors.	Glycine	46-53	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	78-82
11838022-0	2002	Characterization of the elusive disulfide bridge forming human Hb variant: Hb Ta-Li beta83 (EF7)Gly --&gt; Cys by electrospray mass spectrometry.	Glycine	96-99	FAM3 metabolism regulating signaling molecule D	Homo sapiens	92-95
11867224-5	2002	In addition to the N-terminal part, which is similar to the human protein, AtCBP20 has a long C-terminus rich in arginine, glycine and aspartate residues.	Glycine	123-130	CAP-binding protein 20	Arabidopsis thaliana	75-82
12379816-0	2002	Effects of amidated gastrin and glycine-extended gastrin on cell proliferation and crypt fission in parenterally and orally fed rats.	Glycine	32-39	gastrin	Rattus norvegicus	49-56
11736730-2	2001	It raises in situ antibodies against two proliferative forms of gastrin: amidated and glycine-extended gastrin-17.	Glycine	86-93	gastrin	Rattus norvegicus	64-71
11736730-2	2001	It raises in situ antibodies against two proliferative forms of gastrin: amidated and glycine-extended gastrin-17.	Glycine	86-93	gastrin	Rattus norvegicus	103-110
11726274-1	2001	As models of ion channel proteins and naturally occurring pore-forming peptides, we designed a series of Aib rich peptides [Ac-(Aib-Xxx-Aib-Ala)(5)-NH(2) (Xxx = Lys, Glu, Ser, and Gly: BXBA-20)] to investigate the effects of the side chains of the amino acid residues Lys, Glu, Ser, and Gly on the conformation and electrophysiological properties of ion channels.	Glycine	180-183	ANIB1	Homo sapiens	105-108
11726274-1	2001	As models of ion channel proteins and naturally occurring pore-forming peptides, we designed a series of Aib rich peptides [Ac-(Aib-Xxx-Aib-Ala)(5)-NH(2) (Xxx = Lys, Glu, Ser, and Gly: BXBA-20)] to investigate the effects of the side chains of the amino acid residues Lys, Glu, Ser, and Gly on the conformation and electrophysiological properties of ion channels.	Glycine	287-290	ANIB1	Homo sapiens	105-108
11551961-1	2001	The neurotransmitter glycine is removed from the synaptic cleft by two Na(+)-and Cl(-)-dependent transporters, the glial (GLYT1) and neuronal (GLYT2) glycine transporters.	Glycine	21-28	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	143-148
11495912-5	2001	Furthermore, glycine-extended gastrin(17) induced a PI3-kinase-mediated tyrosine phosphorylation of the adherens junction protein beta-catenin, partial dissociation of the complex between beta-catenin and the transmembrane protein E-cadherin, and delocalization of beta-catenin into the cytoplasm.	Glycine	13-20	catenin (cadherin associated protein), beta 1	Mus musculus	130-142
11495912-5	2001	Furthermore, glycine-extended gastrin(17) induced a PI3-kinase-mediated tyrosine phosphorylation of the adherens junction protein beta-catenin, partial dissociation of the complex between beta-catenin and the transmembrane protein E-cadherin, and delocalization of beta-catenin into the cytoplasm.	Glycine	13-20	catenin (cadherin associated protein), beta 1	Mus musculus	188-200
11495912-5	2001	Furthermore, glycine-extended gastrin(17) induced a PI3-kinase-mediated tyrosine phosphorylation of the adherens junction protein beta-catenin, partial dissociation of the complex between beta-catenin and the transmembrane protein E-cadherin, and delocalization of beta-catenin into the cytoplasm.	Glycine	13-20	catenin (cadherin associated protein), beta 1	Mus musculus	188-200
11711044-3	2001	The cholinesterase inhibitor physostigmine at a dose of 3.2 microg/side and D-cycloserine (1.0 and 10 microg/side), which is a partial agonist acting at the glycine binding site of the NMDA receptor/channel complex, reduced the increase in working memory errors induced by 100 ng/side interleukin-1beta.	Glycine	157-164	butyrylcholinesterase	Rattus norvegicus	4-18
11489887-4	2001	The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins.	Glycine	226-233	small ubiquitin like modifier 2	Homo sapiens	63-68
11489887-4	2001	The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins.	Glycine	226-233	small ubiquitin like modifier 2	Homo sapiens	73-78
11489887-4	2001	The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins.	Glycine	226-233	small ubiquitin like modifier 2	Homo sapiens	102-107
11489887-4	2001	The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins.	Glycine	226-233	small ubiquitin like modifier 2	Homo sapiens	120-125
11675599-3	2001	According to the consensus chronology, the pair of complementary GGC and GCC codons for the amino acids alanine and glycine appeared first.	Glycine	116-123	gamma-glutamylcyclotransferase	Homo sapiens	65-68
11445635-9	2001	The G308-->A transition was a nonconservative mutation that changed a glycine into a glutamate at the amino acid residue 74 in the extracellular domain of the mature MPZ/P(0).	Glycine	70-77	myelin protein zero	Homo sapiens	166-169
11445644-3	2001	Brain specimens showed that the leptomeningeal vessels walls were thickened by amyloid deposits, and sequencing of the TTR exons showed a heterozygous single base-pair transition from G to A (codon 53), resulting in a glycine for glutamic acid substitution (G53E).	Glycine	218-225	transthyretin	Homo sapiens	119-122
17855260-10	2007	MLP identified in this report encodes a protein with five tandem LIM-glycine modules.	Glycine	69-76	muscle LIM protein	Bombyx mori	0-3
20641670-5	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Mus musculus	31-42
17877151-5	2007	Cell adhesion was partially inhibited by Arg-Gly-Asp (RGD) peptide, anti-beta1 integrin suggesting that integrin beta1 receptors have roles to play in the process.	Glycine	45-48	integrin subunit beta 1	Homo sapiens	104-118
17503064-7	2007	The C2753T transition resulted in a novel nonsense mutation of glutamine codon (CAG) to a stop codon (TAG) at amino acid residue 865 (Q865X) and the G2090T transition resulted in a novel missense mutation of glycine condon (GGA) to Valine (GUA) at amino acid residue 645 (G645V) in hSPCA1.	Glycine	208-215	ATPase secretory pathway Ca2+ transporting 1	Homo sapiens	282-288
17563362-2	2007	Crystallographic, NMR, and mutation studies of two tandem cytoskeleton-associated protein glycine-rich (CAP-Gly) domains of CLIP-170, CAP-Gly-1 and CAP-Gly-2, revealed positively charged basic grooves of both CAP-Gly domains for tubulin binding, whereas the CAP-Gly-2 domain possesses a more basic groove and directly binds the EExEEY/F motif of the C-terminal acidic-tail ends of alpha-tubulin.	Glycine	90-97	CAP-Gly domain containing linker protein 1	Homo sapiens	124-132
17563362-2	2007	Crystallographic, NMR, and mutation studies of two tandem cytoskeleton-associated protein glycine-rich (CAP-Gly) domains of CLIP-170, CAP-Gly-1 and CAP-Gly-2, revealed positively charged basic grooves of both CAP-Gly domains for tubulin binding, whereas the CAP-Gly-2 domain possesses a more basic groove and directly binds the EExEEY/F motif of the C-terminal acidic-tail ends of alpha-tubulin.	Glycine	108-111	CAP-Gly domain containing linker protein 1	Homo sapiens	124-132
17563362-8	2007	We suggest that CLIP-170 stimulates microtubule polymerization and/or nucleation by neutralizing the negative charges of tubulins with the highly positive charges of the CLIP-170 CAP-Gly domains.	Glycine	183-186	CAP-Gly domain containing linker protein 1	Homo sapiens	16-24
17563362-8	2007	We suggest that CLIP-170 stimulates microtubule polymerization and/or nucleation by neutralizing the negative charges of tubulins with the highly positive charges of the CLIP-170 CAP-Gly domains.	Glycine	183-186	CAP-Gly domain containing linker protein 1	Homo sapiens	170-178
17434460-9	2007	Our data suggest that the TM2-TM3 extracellular loop plays a role in the transduction of signals generated by allosteric modulators in addition to gating signals that follow glycine binding.	Glycine	174-181	tropomyosin 3	Homo sapiens	30-33
17425959-11	2007	DDEB usually involves glycine substitutions within the triple helix of COL7A1 although other missense variants or splice-site alterations may underlie some cases.	Glycine	22-29	collagen type VII alpha 1 chain	Homo sapiens	71-77
17379925-1	2007	Bile acid coenzyme A:amino acid N-acyltransferase (BAT) is responsible for the amidation of bile acids with the amino acids glycine and taurine.	Glycine	124-131	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	0-49
17379925-1	2007	Bile acid coenzyme A:amino acid N-acyltransferase (BAT) is responsible for the amidation of bile acids with the amino acids glycine and taurine.	Glycine	124-131	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	51-54
20641448-0	2004	[(99m)Tc(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) [(99m)Tc-(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) ((99m)Tc(N)(PNP3)-CCK-8) is a radiolabeled peptide developed for single-photon emission computed tomography (SPECT) imaging of tumors that express the gastrin/cholecystokinin-2 (CCK-2) receptor (1).	Glycine	19-22	cholecystokinin	Rattus norvegicus	23-26
20641448-0	2004	[(99m)Tc(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) [(99m)Tc-(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) ((99m)Tc(N)(PNP3)-CCK-8) is a radiolabeled peptide developed for single-photon emission computed tomography (SPECT) imaging of tumors that express the gastrin/cholecystokinin-2 (CCK-2) receptor (1).	Glycine	19-22	cholecystokinin	Rattus norvegicus	64-67
17445538-5	2007	Nucleotide 386 is the second base of codon 129, and A--&gt;G mutation (D129G) changed this codon from Asp(GAC) to Gly(GGC).	Glycine	114-117	gamma-glutamylcyclotransferase	Homo sapiens	118-121
17522368-3	2007	This mutation leads to a Gly/Ser transposition in the prosegment of ANP.	Glycine	25-28	natriuretic peptide A	Rattus norvegicus	68-71
17409447-4	2007	Explanations for the involvement of TTL and detyrosinated tubulin in tumor progression arise from the recent discovery that tubulin detyrosination leads to CAP-Gly protein mislocalization, which correlates with defects in spindle positioning during mitosis.	Glycine	160-163	tubulin tyrosine ligase	Homo sapiens	36-39
17188389-10	2007	CONCLUSIONS: Glycine-induced ATP release in response to a moderate hepatocyte swelling led to the autocrine stimulation of P2 receptors and to the activation of Src, Pyk2 and p38 MAPK that increased hepatocyte resistance to hypoxia by preventing Na+ influx through NHE.	Glycine	13-20	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	161-164
17279631-3	2007	Previously, we used site-directed mutagenesis and functional expression in Xenopus oocytes to identify two pairs of adjacent residues in TMs 7 and 8 of hCNT1 (Ser319-Gln320 and Ser353-Leu354) that, when converted to the corresponding residues in hCNT2 (Gly-Met and Thr-Val, respectively), changed the permeant selectivity of the transporter from cit to cif.	Glycine	253-256	solute carrier family 28 member 1	Homo sapiens	152-157
17279631-3	2007	Previously, we used site-directed mutagenesis and functional expression in Xenopus oocytes to identify two pairs of adjacent residues in TMs 7 and 8 of hCNT1 (Ser319-Gln320 and Ser353-Leu354) that, when converted to the corresponding residues in hCNT2 (Gly-Met and Thr-Val, respectively), changed the permeant selectivity of the transporter from cit to cif.	Glycine	253-256	solute carrier family 28 member 2	Homo sapiens	246-251
17157870-1	2007	The Tyr35--&gt;Gly replacement in bovine pancreatic trypsin inhibitor (BPTI) has previously been shown to dramatically enhance the flexibility of the trypsin-binding region of the free inhibitor and to destabilize the interaction with the protease by about 3 kcal/mol.	Glycine	15-18	spleen trypsin inhibitor I	Bos taurus	34-69
17157870-1	2007	The Tyr35--&gt;Gly replacement in bovine pancreatic trypsin inhibitor (BPTI) has previously been shown to dramatically enhance the flexibility of the trypsin-binding region of the free inhibitor and to destabilize the interaction with the protease by about 3 kcal/mol.	Glycine	15-18	spleen trypsin inhibitor I	Bos taurus	71-75
17137715-10	2007	The peptide Gly(171)-Leu(187) in molar excess inhibited partially the binding of MMP-9 to REGA-3G12 and thus refines the structure of the conformational binding site.	Glycine	12-15	matrix metallopeptidase 9	Homo sapiens	81-86
17157509-6	2007	In the presence of NGP1-01, NMDA/glycine-induced maximal (45)Ca(2+) influx was attenuated by 34% with an insignificant effect on agonist potency.	Glycine	33-40	G protein nucleolar 2	Homo sapiens	19-23
17256745-1	2007	UNLABELLED: Bile acid-coenzyme A:amino acid N-acyltransferase (BAAT) is the sole enzyme responsible for conjugation of primary and secondary bile acids to taurine and glycine.	Glycine	167-174	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	12-61
17256745-1	2007	UNLABELLED: Bile acid-coenzyme A:amino acid N-acyltransferase (BAAT) is the sole enzyme responsible for conjugation of primary and secondary bile acids to taurine and glycine.	Glycine	167-174	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	63-67
17108237-2	2007	We examined the activation of human MRP2-mediated ATP-dependent transport by the choleretic bile salt ursodeoxycholic acid (UDC) and its taurine and glycine amidates in Sf9 cell membranes expressing MRP2 using beta-estradiol 17-(beta-D-glucuronide) (E(2)17G) and beta-estradiol 3-(beta-D-glucuronide) (E(2)3G) as substrates.	Glycine	149-156	ATP binding cassette subfamily C member 2	Homo sapiens	36-40
17166537-7	2007	Crystal structure of the extracellular segment of integrin alphavbeta3 in complexing with an Arg-Gly-Asp ligand.	Glycine	97-100	integrin subunit alpha V	Homo sapiens	50-70
17056724-3	2007	We have designed and expressed a modified form of RD3 that replaces the nine-residue linker with a generic sequence of one serine and eight glycine residues to test the importance of the linker amino acid sequence.	Glycine	140-147	RD3 regulator of GUCY2D	Homo sapiens	50-53
17105729-2	2007	Lipin harboring the fld(2j) (Gly(84) --&gt; Arg) mutation exhibited relatively little PAP activity.	Glycine	29-32	lipin 1	Mus musculus	20-23
18025833-7	2007	RESULTS: Genomic analysis revealed a novel G-to-A transition at the first nucleotide of the 333rd codon of CLCN5, causing a substitution of glycine with arginine.	Glycine	140-147	chloride voltage-gated channel 5	Homo sapiens	107-112
17176063-7	2006	Interestingly, replacing Glu415 in MMP-9 with Gly, its corresponding residue in FC, endowed the enzyme with type I collagenolytic activity.	Glycine	46-49	matrix metallopeptidase 9	Homo sapiens	35-40
16886222-2	2006	Starting with a foundation consisting of an environmentally responsive poly(N-isopropylacrylamide-co-acrylic acid) hydrogel, we incorporated matrix metalloproteinase-13 (MMP-13) degradable crosslinkers and peptides containing integrin-binding domains (i.e., Arg-Gly-Asp) to create a biomimetic matrix designed to encourage osteoblast migration and proliferation.	Glycine	262-265	matrix metallopeptidase 13	Rattus norvegicus	170-176
16989769-0	2006	Bidirectional electron transfer in photosystem I: replacement of the symmetry-breaking tryptophan close to the PsaB-bound phylloquinone A1B with a glycine residue alters the redox properties of A1B and blocks forward electron transfer at cryogenic temperatures.	Glycine	147-154	photosystem I P700 chlorophyll a apoprotein A2	Chlamydomonas reinhardtii	111-115
16989769-1	2006	A conserved tryptophan residue located between the A(1B) and F(X) redox centres on the PsaB side of the Photosystem I reaction centre has been mutated to a glycine in Chlamydomonas reinhardtii, thereby matching the conserved residue found in the equivalent position on the PsaA side.	Glycine	156-163	photosystem I P700 chlorophyll a apoprotein A2	Chlamydomonas reinhardtii	87-91
16989769-8	2006	The results provide further support for the bi-directional model of electron transfer in Photosystem I of C. reinhardtii, and indicate that the replacement of the tryptophan residue with glycine mainly affects the redox properties of the PsaB bound phylloquinone A(1B).	Glycine	187-194	photosystem I P700 chlorophyll a apoprotein A2	Chlamydomonas reinhardtii	238-242
17120122-4	2006	The earliest amino acids, alanine and glycine, have been encoded by GCC and GGC codons, as today.	Glycine	38-45	gamma-glutamylcyclotransferase	Homo sapiens	76-79
17097032-8	2006	With a C-G transversion in nucleotide 13,619 of the MYH7 gene, located at the essential light chain interacting region in S1, the replacement of arginine by glycine took place at amino acid residue 723.	Glycine	157-164	myosin heavy chain 7	Homo sapiens	52-56
17049125-0	2006	Glycine blunts transplantative liver ischemia-reperfusion injury by downregulating interleukin 1 receptor associated kinase-4.	Glycine	0-7	interleukin 1 receptor associated kinase 4	Homo sapiens	83-125
17049125-1	2006	AIM: To determine whether glycine could downregulate interleukin 1 receptor associated kinase-4 (IRAK-4) expression to interfere with lipopolysaccharides (LPS) signal transduction and blunt transplantative liver ischemia-reperfusion injury (I/RI).	Glycine	26-33	interleukin 1 receptor associated kinase 4	Homo sapiens	53-95
17049125-1	2006	AIM: To determine whether glycine could downregulate interleukin 1 receptor associated kinase-4 (IRAK-4) expression to interfere with lipopolysaccharides (LPS) signal transduction and blunt transplantative liver ischemia-reperfusion injury (I/RI).	Glycine	26-33	interleukin 1 receptor associated kinase 4	Homo sapiens	97-103
17049125-8	2006	However, glycine, which led to improved survival rate and liver function, significantly alleviated liver parenchyma cell damage by downregulating IRAK-4, TNF-alpha expression and NF-kappaB transcriptional activity compared with the control group.	Glycine	9-16	interleukin 1 receptor associated kinase 4	Homo sapiens	146-152
17049125-9	2006	CONCLUSION: Glycine can attenuate hepatic I/RI by downregulating IRAK-4 to interfere with LPS signal transduction.	Glycine	12-19	interleukin 1 receptor associated kinase 4	Homo sapiens	65-71
16767770-1	2006	Chiral interaction of helical peptide with chiral molecule, and concomitant induction in its helix sense have been demonstrated in optically inactive nonapeptide (1) possessing Gly at its N-terminus: H-Gly-(Delta(Z)Phe-Aib)(4)-OCH(3) (1: Delta(Z)Phe = Z-dehydrophenylalanine; Aib = alpha-aminoisobutyric acid).	Glycine	177-180	ANIB1	Homo sapiens	219-222
16767770-1	2006	Chiral interaction of helical peptide with chiral molecule, and concomitant induction in its helix sense have been demonstrated in optically inactive nonapeptide (1) possessing Gly at its N-terminus: H-Gly-(Delta(Z)Phe-Aib)(4)-OCH(3) (1: Delta(Z)Phe = Z-dehydrophenylalanine; Aib = alpha-aminoisobutyric acid).	Glycine	177-180	ANIB1	Homo sapiens	276-279
25792788-1	2006	Addition of azurocidin, a protein in granulocytes similar to serine proteases but has no protease activity because of replacement of the active serine residue by glycine, to the incubation mixture containing medullasin induced elastinolytic activity of medullasin.	Glycine	162-169	azurocidin 1	Homo sapiens	12-22
16772309-1	2006	BACKGROUND: The homozygous presence of the arginine-16 variant of the beta(2) adrenoceptor gene ADRB2 reverses the benefits from the regular use of short acting beta(2) agonists in asthmatic adults compared with the homozygous glycine-16 genotype.	Glycine	227-234	adrenoceptor beta 2	Homo sapiens	70-90
16772309-1	2006	BACKGROUND: The homozygous presence of the arginine-16 variant of the beta(2) adrenoceptor gene ADRB2 reverses the benefits from the regular use of short acting beta(2) agonists in asthmatic adults compared with the homozygous glycine-16 genotype.	Glycine	227-234	adrenoceptor beta 2	Homo sapiens	96-101
17098192-4	2006	The analysis of diverse sequences, including those of elastin, amyloids, spider silks, wheat gluten, and insect resilin, reveals a threshold in proline and glycine composition above which amyloid formation is impeded and elastomeric properties become apparent.	Glycine	156-163	elastin	Homo sapiens	54-61
16870265-2	2006	In order to reconstruct the system for identification of short antigenic peptides, the swine SLA-2 gene was linked to the beta(2)m gene via (G4S)3, a linker encoding a 15-amino acid glycine-rich sequence (G4S)3, using splicing overlap extension-PCR (SOE-PCR).	Glycine	182-189	src-like-adapter 2	Sus scrofa	93-98
17002377-1	2006	The molecular basis of the hydroxylation reaction of the Calpha of a C-terminal glycine catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM) was investigated using hybrid quantum-classical (QM-MM) computational techniques.	Glycine	80-87	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	101-150
17002377-1	2006	The molecular basis of the hydroxylation reaction of the Calpha of a C-terminal glycine catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM) was investigated using hybrid quantum-classical (QM-MM) computational techniques.	Glycine	80-87	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	152-155
16905250-1	2006	The potassium-chloride cotransporter 2 (KCC2)-dependent intracellular chloride level determines whether neurons respond to GABA and/or glycine by depolarization or hyperpolarization.	Glycine	135-142	solute carrier family 12 member 5	Homo sapiens	40-44
17014440-9	2006	Unusually for a trypsin-like proteinase however, equine tryptase has alanine at residue 216, rather than glycine, which confers increased arginine substrate specificity in vitro and may restrict fibrinogenolysis in vivo.	Glycine	105-112	proto-oncogene tyrosine-protein kinase receptor Ret	Equus caballus	56-64
16949363-4	2006	They further show how CAP-Gly domains serve as recognition domains for EEY/F-COO(-) motifs, which represent characteristic and functionally important sequence elements in EB, CLIP-170, and alpha-tubulin.	Glycine	26-29	CAP-Gly domain containing linker protein 1	Homo sapiens	175-183
16728452-2	2006	Subjects homozygous for glycine at amino acid 16 (Gly16) of the beta2AR have been shown to have enhanced beta2-mediated vascular relaxation when compared to subjects homozygous for arginine (Arg16).	Glycine	24-31	adrenoceptor beta 2	Homo sapiens	64-71
16740612-2	2006	While receiving a normal Na+ diet (150 mmol day(-1)), subjects homozygous for glycine at amino acid 16 (Gly16) have greater forearm beta2AR-mediated vasodilatation than subjects homozygous for arginine (Arg16), an effect that is mediated by endothelial NO.	Glycine	78-85	adrenoceptor beta 2	Homo sapiens	132-139
16574790-5	2006	Confirming the role of amidation in angiogenesis, Gly-extended and free acid variants of human PAMP produced responses similar to the natural nonamidated peptides.	Glycine	50-53	adrenomedullin	Homo sapiens	95-99
17044971-13	2006	The glycine at this position (G271) is located in pore region of KCNQ2 protein and is evolutionarily highly conserved.	Glycine	4-11	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	65-70
17081364-5	2006	Plasma levels of two molecular forms of AM (an active, mature form [AM-m] and an intermediate, inactive glycine-extended form [AM-Gly]) in the aorta and coronary sinus (CS) were measured by specific immunoradiometric assay after reperfusion.	Glycine	104-111	adrenomedullin	Homo sapiens	40-42
16935250-3	2006	On the peptide array, the relative cell-adhesion ratio of NIH/3T3 cells was 2.5-fold higher on the RGDS (Arg-Gly-Asp-Ser) peptide spot as compared to the spot with no peptide, thus indicating integrin-mediated peptide-cell interaction.	Glycine	109-112	ral guanine nucleotide dissociation stimulator	Mus musculus	99-103
16732284-6	2006	Hydrophobic residues and a glycine in this loop are required for integration into the retromer complex and endosomal localization of human Vps26, and for the function of yeast Vps26 in carboxypeptidase Y sorting.	Glycine	27-34	VPS26, retromer complex component A	Homo sapiens	139-144
16732284-6	2006	Hydrophobic residues and a glycine in this loop are required for integration into the retromer complex and endosomal localization of human Vps26, and for the function of yeast Vps26 in carboxypeptidase Y sorting.	Glycine	27-34	retromer subunit PEP8	Saccharomyces cerevisiae S288C	176-181
16584196-1	2006	The kinetics and thermodynamics of the alkaline and acid conformational transitions of a Lys 79 --&gt; Ala/Asn 52 --&gt; Gly (A79G52) variant of iso-1-cytochrome c are studied.	Glycine	121-124	eukaryotic translation initiation factor 1	Homo sapiens	145-150
16683069-2	2006	Normotensive adults homozygous for glycine (Gly) of the Arg16/Gly beta2-adrenergic receptor polymorphism have a greater forearm beta2-receptor mediated vasodilation and a higher cardiac output response to isometric handgrip than arginine (Arg) homozygotes.	Glycine	35-42	adrenoceptor beta 2	Homo sapiens	66-91
16683069-2	2006	Normotensive adults homozygous for glycine (Gly) of the Arg16/Gly beta2-adrenergic receptor polymorphism have a greater forearm beta2-receptor mediated vasodilation and a higher cardiac output response to isometric handgrip than arginine (Arg) homozygotes.	Glycine	44-47	adrenoceptor beta 2	Homo sapiens	66-91
16683069-2	2006	Normotensive adults homozygous for glycine (Gly) of the Arg16/Gly beta2-adrenergic receptor polymorphism have a greater forearm beta2-receptor mediated vasodilation and a higher cardiac output response to isometric handgrip than arginine (Arg) homozygotes.	Glycine	62-65	adrenoceptor beta 2	Homo sapiens	66-91
16505175-6	2006	Treatment with the NADPH oxidase inhibitor apocynin, a Nox2 (gp91phox) antisense oligonucleotide (Nox2 AS), or the peptide gp91ds-tat significantly reduced Gly-BSA-induced ROS production at 24 hours (68.5+/-2.2%, 61.4+/-8.3%, and 53.2+/-5.4% reduction, respectively).	Glycine	156-159	cytochrome b-245 beta chain	Rattus norvegicus	55-59
16505175-6	2006	Treatment with the NADPH oxidase inhibitor apocynin, a Nox2 (gp91phox) antisense oligonucleotide (Nox2 AS), or the peptide gp91ds-tat significantly reduced Gly-BSA-induced ROS production at 24 hours (68.5+/-2.2%, 61.4+/-8.3%, and 53.2+/-5.4% reduction, respectively).	Glycine	156-159	cytochrome b-245 beta chain	Rattus norvegicus	61-69
16505175-6	2006	Treatment with the NADPH oxidase inhibitor apocynin, a Nox2 (gp91phox) antisense oligonucleotide (Nox2 AS), or the peptide gp91ds-tat significantly reduced Gly-BSA-induced ROS production at 24 hours (68.5+/-2.2%, 61.4+/-8.3%, and 53.2+/-5.4% reduction, respectively).	Glycine	156-159	cytochrome b-245 beta chain	Rattus norvegicus	98-102
16505175-9	2006	Gly-BSA-induced increases in ROS were associated with apocynin-inhibitable nuclear translocation of nuclear factor-kappaB and an increase in atrial natriuretic factor mRNA expression.	Glycine	0-3	natriuretic peptide A	Rattus norvegicus	141-166
16505175-10	2006	CONCLUSIONS: Gly-BSA stimulates cardiomyocyte ROS production through a protein kinase C-dependent activation of a Nox2-containing NADPH oxidase, which results in nuclear factor-kappaB activation and upregulation of atrial natriuretic factor mRNA.	Glycine	13-16	cytochrome b-245 beta chain	Rattus norvegicus	114-118
16505175-10	2006	CONCLUSIONS: Gly-BSA stimulates cardiomyocyte ROS production through a protein kinase C-dependent activation of a Nox2-containing NADPH oxidase, which results in nuclear factor-kappaB activation and upregulation of atrial natriuretic factor mRNA.	Glycine	13-16	natriuretic peptide A	Rattus norvegicus	215-240
16519679-1	2006	The myotonic dystrophy protein kinase polypeptide repertoire in mice and humans consists of six different splice isoforms that vary in the nature of their C-terminal tails and in the presence or absence of an internal Val-Ser-Gly-Gly-Gly motif.	Glycine	226-229	dystrophia myotonica-protein kinase	Mus musculus	4-37
16519679-1	2006	The myotonic dystrophy protein kinase polypeptide repertoire in mice and humans consists of six different splice isoforms that vary in the nature of their C-terminal tails and in the presence or absence of an internal Val-Ser-Gly-Gly-Gly motif.	Glycine	230-233	dystrophia myotonica-protein kinase	Mus musculus	4-37
16519679-1	2006	The myotonic dystrophy protein kinase polypeptide repertoire in mice and humans consists of six different splice isoforms that vary in the nature of their C-terminal tails and in the presence or absence of an internal Val-Ser-Gly-Gly-Gly motif.	Glycine	230-233	dystrophia myotonica-protein kinase	Mus musculus	4-37
16519679-4	2006	Complex formation was impaired in myotonic dystrophy protein kinase mutants in which three leucines at positions a and d in the coiled-coil heptad repeats were mutated to glycines.	Glycine	171-179	DM1 protein kinase	Homo sapiens	34-67
16339181-1	2006	In humans, subjects homozygous for arginine (ArgArg) at codon 16 of the beta2-adrenergic receptor (beta2AR) have been shown to have greater agonist-mediated desensitization than subjects homozygous for glycine (GlyGly).	Glycine	202-209	adrenoceptor beta 2	Homo sapiens	99-106
16303767-6	2006	Each purified mutant Atg8 homolog with an exposed C-terminal Gly formed an E1-substrate intermediate with hAtg7 via a thioester bond in an ATP-dependent manner and formed an E2-substrate intermediate with hAtg3 via a thioester bond dependent on ATP and hAtg7.	Glycine	61-64	GABA type A receptor associated protein like 2	Homo sapiens	21-25
16303767-6	2006	Each purified mutant Atg8 homolog with an exposed C-terminal Gly formed an E1-substrate intermediate with hAtg7 via a thioester bond in an ATP-dependent manner and formed an E2-substrate intermediate with hAtg3 via a thioester bond dependent on ATP and hAtg7.	Glycine	61-64	autophagy related 3	Homo sapiens	205-210
16426244-0	2006	Association between ICAM-1 Gly-Arg polymorphism and renal parenchymal scarring following childhood urinary tract infection.	Glycine	27-30	intercellular adhesion molecule 1	Homo sapiens	20-26
16418218-8	2006	Immunoprecipitation analysis showed that JAM-A interacts with integrin alpha(v)beta(3), and this association was increased by engagement of the ligand-binding site of the integrin by Arg-Gly-Asp-Ser (RGDS) peptide.	Glycine	187-190	F11 receptor	Homo sapiens	41-46
16418218-8	2006	Immunoprecipitation analysis showed that JAM-A interacts with integrin alpha(v)beta(3), and this association was increased by engagement of the ligand-binding site of the integrin by Arg-Gly-Asp-Ser (RGDS) peptide.	Glycine	187-190	integrin subunit alpha V	Homo sapiens	62-85
16291749-1	2006	The neuron-specific K(+)-Cl(-) cotransporter KCC2 plays a crucial role in determining intracellular chloride activity and thus the neuronal response to gamma-aminobutyric acid and glycine.	Glycine	180-187	solute carrier family 12 member 5	Homo sapiens	45-49
16899523-2	2006	In adult plants, two genes encoding mitochondrial isoforms m-AlaAT and alanine-glyoxylate aminotransferase (AGT), catalysing, respectively, reversible reactions of alanine/oxoglutarate&lt;==&gt;glutamate/pyruvate and alanine/glyoxylate&lt;==&gt;glycine/pyruvate, were expressed in roots, stems, and leaves.	Glycine	245-252	alanine aminotransferase 2	Medicago truncatula	61-66
16369119-1	2006	BACKGROUND: beta(2)-Adrenergic receptor (beta(2)-AR) polymorphisms occurring at amino acid position 16 (Arg-Gly) and 27 (Gln-Glu) are known to be functionally relevant and also disease-modifying in subjects with asthma.	Glycine	108-111	adrenoceptor beta 2	Homo sapiens	12-39
16369119-1	2006	BACKGROUND: beta(2)-Adrenergic receptor (beta(2)-AR) polymorphisms occurring at amino acid position 16 (Arg-Gly) and 27 (Gln-Glu) are known to be functionally relevant and also disease-modifying in subjects with asthma.	Glycine	108-111	adrenoceptor beta 2	Homo sapiens	41-51
16369120-1	2006	BACKGROUND: As a result of the finding that the mutation of Arg into Gly at beta(2)-adrenergic receptor (beta(2)-AR)16 loci could promote the downregulation effect triggered by the beta(2)-agonist, it was supposed that Gly16 might be associated with the downregulation of beta(2)-AR in patients with nocturnal asthma.	Glycine	69-72	adrenoceptor beta 2	Homo sapiens	105-115
16369120-1	2006	BACKGROUND: As a result of the finding that the mutation of Arg into Gly at beta(2)-adrenergic receptor (beta(2)-AR)16 loci could promote the downregulation effect triggered by the beta(2)-agonist, it was supposed that Gly16 might be associated with the downregulation of beta(2)-AR in patients with nocturnal asthma.	Glycine	69-72	adrenoceptor beta 2	Homo sapiens	272-282
16369120-5	2006	RESULTS: The distribution frequency of genotype Arg/Arg, Arg/Gly, and Gly/Gly at beta(2)-AR 16 loci was 12, 16 and 72% in the nocturnal asthma group; and 27, 41 and 32% in the non-nocturnal asthma group.	Glycine	70-73	adrenoceptor beta 2	Homo sapiens	81-91
16369120-5	2006	RESULTS: The distribution frequency of genotype Arg/Arg, Arg/Gly, and Gly/Gly at beta(2)-AR 16 loci was 12, 16 and 72% in the nocturnal asthma group; and 27, 41 and 32% in the non-nocturnal asthma group.	Glycine	70-73	adrenoceptor beta 2	Homo sapiens	81-91
16339725-6	2005	A spontaneous suppressor of this slow-growth phenotype was found to convert a conserved glycine to serine in the beta subunit of F(1)-ATPase (atp2-227).	Glycine	88-95	F1F0 ATP synthase subunit beta	Saccharomyces cerevisiae S288C	142-146
16317684-6	2005	Madin Darby canine kidney cells coexpressing mouse Ostalpha and Ostbeta exhibited enhanced apical to basolateral transport of the major glycine and taurine conjugated bile acid species.	Glycine	136-143	solute carrier family 51, alpha subunit	Mus musculus	51-59
16162493-5	2005	Moreover, a structural basis for R chiral specificity is also revealed; creation of a small oxygen pocket next to Gly(428) (Ala in all S-LOX isozymes) promoted C-8 oxygenation with R chirality on the activated fatty acid substrate.	Glycine	114-117	lysyl oxidase	Homo sapiens	137-140
16157595-1	2005	Recent findings associate the control of stereochemistry in lipoxygenase (LOX) catalysis with a conserved active site alanine for S configuration hydroperoxide products, or a corresponding glycine for R stereoconfiguration.	Glycine	189-196	linoleate 9S-lipoxygenase-4	Glycine max	60-72
16157595-1	2005	Recent findings associate the control of stereochemistry in lipoxygenase (LOX) catalysis with a conserved active site alanine for S configuration hydroperoxide products, or a corresponding glycine for R stereoconfiguration.	Glycine	189-196	linoleate 9S-lipoxygenase-4	Glycine max	74-77
16181611-3	2005	Measurement of membrane potentials shows that PEPT1- transfected STC-1 cells are depolarized by di-peptide glycyl-glycine but not by glycine monomer.	Glycine	114-121	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	46-51
16271045-1	2005	Recent evidence indicates that the glycine transporter-1 (GLYT1) plays a role in regulation of NMDA receptor function through tight control of glycine concentration in its surrounding medium.	Glycine	35-42	solute carrier family 6 member 9	Rattus norvegicus	58-63
16271045-8	2005	We hypothesize that PSD-95 might act as a scaffold for GLYT1 and NMDA receptors, allowing GLYT1 to regulate the concentrations of glycine in the micro-environment of NMDA receptors.	Glycine	130-137	solute carrier family 6 member 9	Rattus norvegicus	55-60
16271045-8	2005	We hypothesize that PSD-95 might act as a scaffold for GLYT1 and NMDA receptors, allowing GLYT1 to regulate the concentrations of glycine in the micro-environment of NMDA receptors.	Glycine	130-137	solute carrier family 6 member 9	Rattus norvegicus	90-95
16373326-10	2005	The functional characteristics of rabbit PAT1 in either mammalian cells or renal BBMV suggest that PAT1 is the low-affinity transporter of proline, glycine and hydroxyproline believed to be defective in patients with iminoglycinuria.	Glycine	148-155	solute carrier family 36 (proton/amino acid symporter), member 1	Mus musculus	41-45
16216070-0	2005	Mutagenesis of Glycine 179 modulates both catalytic efficiency and reduced pyridine nucleotide specificity in cytochrome b5 reductase.	Glycine	15-22	cytochrome b5 type A	Rattus norvegicus	110-123
20641210-7	2004	A tripeptide sequence consisting of Arg-Gly-Asp (RGD) is identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including alphavbeta3.	Glycine	40-43	vitronectin	Mus musculus	130-141
16081882-2	2005	Transfection studies with elastin cDNAs demonstrate that the glycine to aspartate change compromises the ability of the mutant protein to undergo normal elastin assembly.	Glycine	61-68	elastin	Homo sapiens	26-33
16081882-2	2005	Transfection studies with elastin cDNAs demonstrate that the glycine to aspartate change compromises the ability of the mutant protein to undergo normal elastin assembly.	Glycine	61-68	elastin	Homo sapiens	153-160
16171377-0	2005	Bench meets bedside: a 10-year-old girl and amino acid residue glycine 75 of the facilitative glucose transporter GLUT1.	Glycine	63-70	solute carrier family 2 member 1	Homo sapiens	114-119
16112640-0	2005	Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.	Glycine	128-131	cytochrome P450 family 4 subfamily F member 8	Homo sapiens	139-145
16112640-7	2005	CYP4F enzymes with omega-hydroxylase activity contain a heme-binding Glu residue, whereas CYP4F8 (and CYP4F12) with omega2- and omega 3-hydroxylase activities has a Gly residue in this position of SRS-4.	Glycine	165-168	cytochrome P450 family 4 subfamily F member 8	Homo sapiens	90-96
16051266-1	2005	T-protein, a component of the glycine cleavage system, catalyzes the formation of ammonia and 5,10-methylenetetrahydrofolate from the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein.	Glycine	30-37	myosin binding protein H	Homo sapiens	200-209
16051266-1	2005	T-protein, a component of the glycine cleavage system, catalyzes the formation of ammonia and 5,10-methylenetetrahydrofolate from the aminomethyl moiety of glycine attached to the lipoate cofactor of H-protein.	Glycine	156-163	myosin binding protein H	Homo sapiens	200-209
16141513-5	2005	This review introduces our novel "cell delivery system," which employs an Arg-Gly-Asp (RGD) fiber-mutant adenovirus vector encoding the chemokine or chemokine receptor gene in cancer immunotherapy.	Glycine	78-81	C-X-C motif chemokine receptor 4	Homo sapiens	149-167
15961556-2	2005	Two recessive mutations in fibroblast growth factor-23 (FGF23), serine 71/glycine (S71G) and serine 129/phenylalanine (S129F), were identified as causing TC.	Glycine	74-81	fibroblast growth factor 23	Homo sapiens	27-54
15961556-2	2005	Two recessive mutations in fibroblast growth factor-23 (FGF23), serine 71/glycine (S71G) and serine 129/phenylalanine (S129F), were identified as causing TC.	Glycine	74-81	fibroblast growth factor 23	Homo sapiens	56-61
15961556-3	2005	Herein, we undertook comprehensive biochemical analyses of an extended TC family carrying the S71G FGF23 mutation, which revealed that heterozygous (serine/glycine, S/G) individuals had elevated serum FGF23 C-terminal fragments compared with wild-type (serine/serine, S/S) family members (P &lt; 0.025).	Glycine	156-163	fibroblast growth factor 23	Homo sapiens	99-104
15961556-3	2005	Herein, we undertook comprehensive biochemical analyses of an extended TC family carrying the S71G FGF23 mutation, which revealed that heterozygous (serine/glycine, S/G) individuals had elevated serum FGF23 C-terminal fragments compared with wild-type (serine/serine, S/S) family members (P &lt; 0.025).	Glycine	156-163	fibroblast growth factor 23	Homo sapiens	201-206
15929988-7	2005	Cathepsin L initially released a shorter Gln(151)-Gly(160) peptide and completed processing at Ser(145) or Gly(143) at the C terminus of the N-terminal 23-kDa TRAP subunit and at Arg(163) at the N terminus of the C-terminal 16-kDa TRAP subunit.	Glycine	107-110	acid phosphatase 5, tartrate resistant	Rattus norvegicus	159-163
15722127-1	2005	A non-peptide mimic of the Arg-Gly Asp (RGD) active sequence of adhesive proteins (such as vitronectin) has been equipped with two different spacer-arms for surface anchorage.	Glycine	31-34	vitronectin	Homo sapiens	91-102
16021449-5	2005	A direct antisuppressor effect of overproduced mRF1 is observed, since the MRF1 gene on a multicopy plasmid causes Gly(-) phenotypes of the leaky mit(-) point mutations in mtDNA.	Glycine	115-118	Mrf1p	Saccharomyces cerevisiae S288C	75-79
15790752-3	2005	Alternatively, a previous report in vitro suggests that preparations of L-AP4 may nonspecifically activate NMDA channels due to glycine contamination (Contractor A, Gereau RW, Green T, and Heinemann SF.	Glycine	128-135	replication initiator 1	Rattus norvegicus	74-77
16020665-1	2005	Elastin-like polypeptides are biopolymers composed of the pentapeptide repeat Val-Pro-Gly-Xaa-Gly.	Glycine	86-89	elastin	Homo sapiens	0-7
15985154-3	2005	RESULTS: Among 28 human tetraspanin proteins, the TM1-3 sequences display a distinct heptad repeat motif (abcdefg)n. In TM1, position a is occupied by structurally conserved bulky residues and position d contains highly conserved Asn and Gly residues.	Glycine	238-241	tropomyosin 3	Homo sapiens	50-55
15817460-4	2005	When the region of col1a1 encompassing the C-terminal glycine repeat and C-prodomain (amino acids 1000-1453) was affinity-labeled with human placental alkaline phosphatase, the secreted trimeric fusion protein could bind to the surface of Ras-transformed cells.	Glycine	54-61	collagen type I alpha 1 chain	Homo sapiens	19-25
15826867-1	2005	The vesicular inhibitory amino acid transporter, VIAAT (also known as vesicular GABA transporter VGAT) transports GABA or glycine into synaptic vesicles.	Glycine	122-129	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	49-54
15826867-1	2005	The vesicular inhibitory amino acid transporter, VIAAT (also known as vesicular GABA transporter VGAT) transports GABA or glycine into synaptic vesicles.	Glycine	122-129	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	97-101
15862787-4	2005	In the present study, we investigated functional characteristics of PEPT2 mediated transport of Gly-Sar in primary cultured astrocytes from mouse cerebral cortex and examined the effects of Na+/H+ exchanger (NHE) inhibitor on Gly-Sar uptake in mouse astrocytes.	Glycine	96-99	solute carrier family 15 (H+/peptide transporter), member 2	Mus musculus	68-73
15826655-11	2005	Our studies suggest that the glycine-rich domain is essential for splicing regulation by human and fly TDP43.	Glycine	29-36	TAR DNA-binding protein-43 homolog	Drosophila melanogaster	103-108
15650063-4	2005	By positional cloning, rescue, and morpholino knockdown experiments, we demonstrate that crs encodes a conserved mitochondrial matrix chaperone HSPA9B containing a glycine-to-glutamate substitution within the substrate-binding domain.	Glycine	164-171	heat shock protein 9	Danio rerio	144-150
15814646-7	2005	A hexapeptide, anti-Flt1 (Gly-Asn-Gln-Trp-Phe-Ile or GNQWFI), was identified from peptide libraries.	Glycine	26-29	FMS-like tyrosine kinase 1	Mus musculus	20-24
15854340-4	2005	High performance liquid chromatography was employed to monitor the continuous changes of glutamic acid (Glu), aspartic acid (Asp), Tau and glycine (Gly) in the hippocampus CA1 region at anaesthesia periods, CPB stage, pre 30 minutes in DHCA, post 30 minutes in DHCA, pre 30 minutes in rewarming, post 30 minutes in rewarming.	Glycine	139-146	carbonic anhydrase 1	Oryctolagus cuniculus	172-175
15598574-0	2005	Synthesis and pharmacological evaluation of glycine-modified analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).	Glycine	44-51	glycophorin E (MNS blood group)	Homo sapiens	133-136
15598574-2	2005	Pharmacological evaluation of the novel compounds was undertaken to further understand the role of the glycine residue on the observed neuroprotective properties of the endogenous tripeptide GPE.	Glycine	103-110	glycophorin E (MNS blood group)	Homo sapiens	191-194
16508120-2	2005	The Kelch/DGR (double-glycine repeat) domain of Keap1 associates with Nrf2 as well as with actin filaments.	Glycine	22-29	kelch-like ECH-associated protein 1	Mus musculus	48-53
15530480-4	2004	RESULTS: Prolidase activity against glycylproline in erythrocytes from normal human was strongly enhanced by glycine, L-alanine, L-serine with MnCl(2), but the activity was strongly inhibited by L-valine, and L-leucine.	Glycine	109-116	peptidase D	Homo sapiens	9-18
15530480-6	2004	The prolidase activity against methionylproline in erythrocytes from the patient with prolidase deficiency was also enhanced by glycine, L-alanine and L-serine.	Glycine	128-135	peptidase D	Homo sapiens	4-13
15530480-8	2004	CONCLUSION: Prolidase activity against glycylproline in normal human erythrocytes and against methionylproline from the prolidase-deficient patient was enhanced strongly by glycine, alanine and serine with MnCl(2).	Glycine	173-180	peptidase D	Homo sapiens	12-21
15530480-8	2004	CONCLUSION: Prolidase activity against glycylproline in normal human erythrocytes and against methionylproline from the prolidase-deficient patient was enhanced strongly by glycine, alanine and serine with MnCl(2).	Glycine	173-180	peptidase D	Homo sapiens	120-129
15542783-6	2004	A lead peptide substrate with the sequence Gly-Lys-Ala-Phe-Arg-Arg (GKAFRR) was hydrolyzed by hK2 with a Km of 26.5 micromol/L, kcat of 1.09 s(-1), and a kcat/Km ratio of 41,132 s(-1) mol/L(-1).	Glycine	43-46	RBPJ pseudogene 3	Homo sapiens	94-97
15175365-12	2004	We suggest that modulation of glycine concentration by GLYT1 is an important mechanism to regulate NMDAR-mediated synaptic transmission.	Glycine	30-37	solute carrier family 6 member 9	Rattus norvegicus	55-60
15334382-0	2004	The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study.	Glycine	38-41	adrenoceptor beta 2	Homo sapiens	4-31
15225720-1	2004	Elevation of glycine levels and activation of the NMDA receptor by inhibition of the glycine transporter 1 (GlyT-1) is a potential strategy for the treatment of schizophrenia.	Glycine	13-20	solute carrier family 6 member 9	Rattus norvegicus	85-106
15225720-1	2004	Elevation of glycine levels and activation of the NMDA receptor by inhibition of the glycine transporter 1 (GlyT-1) is a potential strategy for the treatment of schizophrenia.	Glycine	13-20	solute carrier family 6 member 9	Rattus norvegicus	108-114
15073187-5	2004	All six native cysteine residues of GLUT1 were changed to either glycine or serine residues by site-directed mutagenesis, resulting in a functional Glut1 construct with Cys mutated to Gly/Ser (C-less).	Glycine	65-72	solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog	Xenopus laevis	148-153
15073187-5	2004	All six native cysteine residues of GLUT1 were changed to either glycine or serine residues by site-directed mutagenesis, resulting in a functional Glut1 construct with Cys mutated to Gly/Ser (C-less).	Glycine	184-187	solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog	Xenopus laevis	36-41
15073187-5	2004	All six native cysteine residues of GLUT1 were changed to either glycine or serine residues by site-directed mutagenesis, resulting in a functional Glut1 construct with Cys mutated to Gly/Ser (C-less).	Glycine	184-187	solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog	Xenopus laevis	148-153
15157071-8	2004	Herein, we show that the octanoylated derivative of the lipoyl-bearing subunit of the glycine cleavage system (H-protein) is also a substrate for LipA, providing further evidence that the cofactor is synthesized on its target protein.	Glycine	86-93	myosin binding protein H	Homo sapiens	111-120
15031292-7	2004	The homologous tyrosine within the motif Tyr-(Leu/Met)-Gly is conserved in a variety of PTB domains, and this suggests that PTB tyrosine phosphorylation occurs in other proteins.	Glycine	55-58	polypyrimidine tract binding protein 1	Homo sapiens	88-91
15031292-7	2004	The homologous tyrosine within the motif Tyr-(Leu/Met)-Gly is conserved in a variety of PTB domains, and this suggests that PTB tyrosine phosphorylation occurs in other proteins.	Glycine	55-58	polypyrimidine tract binding protein 1	Homo sapiens	124-127
15115517-3	2004	Mutations in the COL7A1 gene, especially in glycine residues within Gly-X-Y repeats, have been shown to cause this form of DDEB.	Glycine	44-51	collagen type VII alpha 1 chain	Homo sapiens	17-23
15115517-3	2004	Mutations in the COL7A1 gene, especially in glycine residues within Gly-X-Y repeats, have been shown to cause this form of DDEB.	Glycine	68-71	collagen type VII alpha 1 chain	Homo sapiens	17-23
15115517-5	2004	Using PCR and direct sequence analysis we have identified a G--&gt;T transversion at nucleotide 7097 in exon 92 of COL7A1, converting a glycine residue to valine (G2366V).	Glycine	136-143	collagen type VII alpha 1 chain	Homo sapiens	115-121
15099830-1	2004	Equilibrium binding dynamics is studied for a panel of benzimidazole-containing compounds at the remodeled interface between human growth hormone (hGH) and the extracellular domain of its receptor (hGHbp), engineered by mutating to glycine hot spot residues T175 from the hormone and W104 from the receptor.	Glycine	232-239	growth hormone receptor	Homo sapiens	198-203
14970226-10	2004	Conversely, mutating the moderately conserved residue (Gly-346) abrogated gp120 binding but enhanced ICAM-2 and ICAM-3 binding.	Glycine	55-58	intercellular adhesion molecule 3	Homo sapiens	112-118
15052619-3	2004	Direct sequencing of the mitochondrial DNA (mtDNA) coding regions revealed a novel missense mutation (G15497A) resulting in a glycine--&gt;serine conversion at a highly conserved site in the cytochrome b gene in the subject, his mother, and sister.	Glycine	126-133	mitochondrially encoded cytochrome b	Homo sapiens	191-203
14701797-7	2004	Alanine-scanning mutagenesis identified residues Tyr(149), Phe(150), Gly(152), Phe(154), and Phe(156) as the key positions for chemerinR activation.	Glycine	69-72	chemerin chemokine-like receptor 1	Homo sapiens	127-136
14645232-1	2004	Glycine specifically induces genes encoding subunits of the glycine decarboxylase complex (GCV1, GCV2, and GCV3), and this is mediated by a fall in cytoplasmic levels of 5,10-methylenetetrahydrofolate caused by inhibition of cytoplasmic serine hydroxymethyltransferase.	Glycine	0-7	glycine decarboxylase subunit H	Saccharomyces cerevisiae S288C	107-111
14645232-4	2004	The genome-wide response to glycine revealed that several other genes are rapidly co-induced with the GCV genes, including SHM2, which encodes cytoplasmic serine hydroxymethyltransferase.	Glycine	28-35	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	123-127
14572308-1	2004	Rat intestinal mucin Muc3 (rMuc3), like its human homologue (MUC3) and several other membrane mucins, contains a C-terminally located SEA (sea urchin sperm protein, enterokinase and agrin) module, with an intrinsic proteolytic site sequence G downward arrow SIVV (where G downward arrow S is the glycine serine cleavage site).	Glycine	296-303	mucin 3	Rattus norvegicus	27-32
14992291-7	2004	The Na+ Hill coefficient of glycine uptake was 2.0, as has been reported for Glyt-2.	Glycine	28-35	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	77-83
15381281-5	2004	Double-label studies showed that NK1 receptor-expressing bipolar cells constituted a population of ON-type cone bipolar cells, since they were distinct from rod bipolar cells and contained glycine.	Glycine	189-196	tachykinin receptor 1	Mus musculus	33-45
11343278-2	2001	In the attempt to synthesize cross-linked elastin-mimetic polypeptides, the repeating sequence VGGVG (V: valine; G: glycine), typical of elastin, was modified to incorporate lysine residues, yielding the polymer poly(KGGVG) (K: lysine).	Glycine	116-123	elastin	Homo sapiens	42-49
11343278-2	2001	In the attempt to synthesize cross-linked elastin-mimetic polypeptides, the repeating sequence VGGVG (V: valine; G: glycine), typical of elastin, was modified to incorporate lysine residues, yielding the polymer poly(KGGVG) (K: lysine).	Glycine	116-123	elastin	Homo sapiens	137-144
11445189-0	2001	Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes.	Glycine	46-53	solute carrier family 6 member 9	Rattus norvegicus	66-72
11445189-4	2001	HEK293 cells expressing human GlyT-1c or GlyT-2 showed high levels of Na(+)-dependent glycine uptake, with K(m) values of 117+/-13 and 200+/-22 microM, respectively.	Glycine	86-93	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	41-47
11445189-6	2001	Efflux of pre-loaded [3H]-glycine from GlyT-1c cells was increased by glycine or sarcosine, whereas NFPS had no effect on its own but blocked the effects of glycine or sarcosine.	Glycine	26-33	solute carrier family 6 member 9	Rattus norvegicus	39-45
11445189-6	2001	Efflux of pre-loaded [3H]-glycine from GlyT-1c cells was increased by glycine or sarcosine, whereas NFPS had no effect on its own but blocked the effects of glycine or sarcosine.	Glycine	70-77	solute carrier family 6 member 9	Rattus norvegicus	39-45
11445189-6	2001	Efflux of pre-loaded [3H]-glycine from GlyT-1c cells was increased by glycine or sarcosine, whereas NFPS had no effect on its own but blocked the effects of glycine or sarcosine.	Glycine	70-77	solute carrier family 6 member 9	Rattus norvegicus	39-45
11445189-12	2001	Overall, our findings indicate that high-affinity glycine uptake in cerebral cortex occurs predominantly via GlyT-1.	Glycine	50-57	solute carrier family 6 member 9	Rattus norvegicus	109-115
11412813-3	2001	The B2AR polymorphism of interest involves a single nucleotide change from A to G, resulting in an amino acid change from Arginine (Arg) to Glycine (Gly).	Glycine	140-147	adrenoceptor beta 2	Homo sapiens	4-8
11412813-3	2001	The B2AR polymorphism of interest involves a single nucleotide change from A to G, resulting in an amino acid change from Arginine (Arg) to Glycine (Gly).	Glycine	140-143	adrenoceptor beta 2	Homo sapiens	4-8
11442002-4	2001	The mutated maternal allele has the substitution of Ser (AGT) in place of Gly (GGT) at codon 498 (G498S) of the TSH receptor.	Glycine	74-77	thyroid stimulating hormone receptor	Homo sapiens	112-124
11305908-1	2001	Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	183-190	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	10-41
11305908-1	2001	Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	183-190	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	43-47
11304516-4	2001	The pretreatment of vascular smooth muscle cells with Ang-(1-7) followed by treatment with acidic glycine to remove surface-bound peptide resulted in a significant decrease in [(125)I]Ang II binding; however, reduced Ang II binding was observed only at micromolar concentrations of Ang-(1-7).	Glycine	98-105	angiogenin	Rattus norvegicus	282-290
2677049-7	1989	Asp244, which is substituted for the Gly found in dog tryptase and in most serine proteases, is present in the putative substrate binding pocket and may confer additional substrate specificity on human tryptase for basic residues.	Glycine	37-40	tryptase	Canis lupus familiaris	54-62
2677049-7	1989	Asp244, which is substituted for the Gly found in dog tryptase and in most serine proteases, is present in the putative substrate binding pocket and may confer additional substrate specificity on human tryptase for basic residues.	Glycine	37-40	tryptase	Canis lupus familiaris	202-210
2552299-1	1989	Novel antibodies were raised against a synthetic NH2-terminal myristoyl(Myr-) tetrapeptide(N-Myr-Gly-Ser-Ser-Lys) which is characteristic of an NH2-terminal portion of pp60v-src, the transforming protein of Rous sarcoma virus.	Glycine	97-100	p60 src	Rous sarcoma virus	174-177
2773809-8	1989	Clustering was also induced by the addition of the GPIIb-IIIa binding domains of fibrinogen--namely, the tetrapeptide Arg-Gly-Asp-Ser on the alpha-chain or the gamma-chain decapeptide gamma 402-411.	Glycine	122-125	integrin subunit alpha 2b	Homo sapiens	51-56
2660900-4	1989	A search for other mutations in N-RAS exon-1 in T-ALL revealed a codon 13 mutation substituting aspartic acid (GAT) for glycine (GGT) in one of 18 patients.	Glycine	120-127	NRAS proto-oncogene, GTPase	Homo sapiens	32-37
2660900-4	1989	A search for other mutations in N-RAS exon-1 in T-ALL revealed a codon 13 mutation substituting aspartic acid (GAT) for glycine (GGT) in one of 18 patients.	Glycine	120-127	glycine-N-acyltransferase	Homo sapiens	111-114
2539974-1	1989	The internalization of [125I]secretin in pancreatic acinar cells was evaluated by differentiation of surface-bound and internalized radioligand with an acidified glycine buffer.	Glycine	162-169	secretin	Homo sapiens	29-37
2542835-8	1989	The enhancement of aspartate signal transduction by glycine and D-serine was inhibited by the noncompetitive GC1 receptor antagonist, phencyclidine, but was even more evident in presence of Mg2+ ions.	Glycine	52-59	solute carrier family 25 member 22	Rattus norvegicus	109-112
2542835-9	1989	Hence, glycine and D-serine may function as positive allosteric modulators of signal transduction at NMDA-sensitive (GC1) glutamate receptors.	Glycine	7-14	solute carrier family 25 member 22	Rattus norvegicus	117-120
2464704-6	1989	The env precursor polyprotein gp160 is cleaved between arginine 526 and glycine 527 to give rise to the external glycoprotein and the transmembrane of SIVMAC.	Glycine	72-79	envelope protein	Simian immunodeficiency virus	4-7
2462607-0	1989	CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide.	Glycine	52-55	integrin subunit alpha M	Homo sapiens	5-10
2710278-4	1989	The release of [14C]glycine from P1 and P2 synaptosomal fractions was markedly increased by raising potassium concentration in the medium, in a partially Ca2+-dependent manner.	Glycine	15-27	crystallin gamma F, pseudogene	Homo sapiens	33-42
2568664-2	1989	It is now apparent that MAO-B is capable of oxidizing inert non-polar amines such as MPTP (N-methyl-4-phenyl-1,2,3,6, tetrahydropyridine) and milacemide (2-n-pentylaminoacetamide) into neuroactive substances giving rise to Parkinson inducing dopaminergic neurotoxin, MPP+ and inhibitory amino acid neurotransmitter, glycine respectively.	Glycine	316-323	monoamine oxidase B	Homo sapiens	24-29
2481875-2	1989	We have demonstrated that the major epitopes recognised by anti-RANA antibodies are represented by a synthetic peptide, P62, corresponding to part of the internal repeat sequence which contains only the amino acids glycine and alanine.	Glycine	215-222	nucleoporin 62	Homo sapiens	120-123
11289130-3	2001	Resistance to this peptide and another toxic peptide derivative, which is based on a Thr-His-Thr-Nle-Glu-Gly backbone conjugated to butyl and benzyl groups (4A6), could be reversed by MRP1 inhibitors.	Glycine	105-108	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	Mus musculus	184-188
2481875-6	1989	This suggests that the specific increase of anti-P62 antibodies in RA may be due to cross-reactions with autoantibodies to structural proteins with repeat sequences containing glycine.	Glycine	176-183	nucleoporin 62	Homo sapiens	49-52
3180219-4	1988	DNA analysis of the un mutant revealed a point mutation in a highly conserved part of the paired box of Pax 1, leading to a Gly-Ser replacement.	Glycine	124-127	paired box 1	Mus musculus	104-109
11232563-4	2001	Affected individuals have a serine to glycine mutation within the casein kinase Iepsilon (CKIepsilon) binding region of hPER2, which causes hypophosphorylation by CKIepsilon in vitro.	Glycine	38-45	period circadian regulator 2	Homo sapiens	120-125
11031256-4	2001	We have generated a mutant of LMP1 with four point mutations; amino acids 204, 206, and 208 were mutated to alanine, and amino acid 384 was mutated to glycine.	Glycine	151-158	PDZ and LIM domain 7	Homo sapiens	30-34
2485226-9	1988	Moreover, they provide evidence that the Arg-Gly-Asp sequence is the only, or essential, GP IIb-IIIa binding site in the vWF molecule.	Glycine	45-48	integrin alpha-IIb	Oryctolagus cuniculus	89-95
11260188-6	2001	We identified a glycine substitution mutation, G1776A, in exon 61 of COL7A1, characteristic of dominant dystrophic EB, which segregated with nail dystrophy in this family.	Glycine	16-23	collagen type VII alpha 1 chain	Homo sapiens	69-75
11260189-5	2001	In each case the COL7A1 mutation comprised the same glycine substitution, G2043R.	Glycine	52-59	collagen type VII alpha 1 chain	Homo sapiens	17-23
14557272-3	2003	Each amino acid residue within the TM10 sequence, 4844IIFDITFFFFVIVILLAIIQGLII4867, of the mouse RyR2 was mutated to either alanine or glycine.	Glycine	135-142	ryanodine receptor 2, cardiac	Mus musculus	97-101
3202824-4	1988	In the third week of life the immediate precursor of amidated gastrin, glycine-extended gastrin, accumulated, and at weaning (day 21) the concentrations exceeded those of amidated gastrin.	Glycine	71-78	gastrin	Rattus norvegicus	62-69
14644153-4	2003	Biochemical studies demonstrated that PSKH1 is myristoylated on glycine 2 and palmitoylated on cysteine 3.	Glycine	64-71	protein serine kinase H1	Homo sapiens	38-43
3202824-4	1988	In the third week of life the immediate precursor of amidated gastrin, glycine-extended gastrin, accumulated, and at weaning (day 21) the concentrations exceeded those of amidated gastrin.	Glycine	71-78	gastrin	Rattus norvegicus	88-95
11135364-3	2001	One of the substituted amino acids is serine 25, which is a glycine in chicken stathmin.	Glycine	60-67	stathmin 1	Gallus gallus	79-87
3202824-4	1988	In the third week of life the immediate precursor of amidated gastrin, glycine-extended gastrin, accumulated, and at weaning (day 21) the concentrations exceeded those of amidated gastrin.	Glycine	71-78	gastrin	Rattus norvegicus	88-95
14643524-0	2003	Compound heterozygosity for premature termination codon and glycine substitution mutations in the COL7A1 gene in Korean siblings with a moderately severe phenotype of recessive dystrophic epidermolysis bullosa.	Glycine	60-67	collagen type VII alpha 1 chain	Homo sapiens	98-104
3129437-6	1988	The Gly-24 TR behaves identically to the wild-type TR when cells are treated with PMA.	Glycine	4-7	transferrin receptor protein 1	Cricetulus griseus	11-13
14534363-9	2003	In contrast, an antagonist rhodamine-Ac-Cys-Glu-His-(d-Nal)-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2 (HS014) bound to and colocalized with MC4R-GFP on the cell surface and did not stimulate receptor internalization.	Glycine	68-71	melanocortin 4 receptor	Homo sapiens	134-138
11146000-7	2001	Taken with the observation that mutation of either Ser(345,346) or of the beta ARK phosphorylation sites prevented both the hyper-phosphorylation and constitutive desensitization of a palmitoylation-less mutant (Gly(341)beta(2)AR), our data suggest a concerted/synergistic action of the two kinases that depends on the palmitoylation state of the receptor.	Glycine	212-215	adrenoceptor beta 2	Homo sapiens	220-229
11146000-8	2001	Consistent with this notion, in vitro phosphorylation of Gly(341)beta(2)AR by the catalytic subunit of PKA facilitated further phosphorylation of the receptor by purified beta ARK.	Glycine	57-60	adrenoceptor beta 2	Homo sapiens	65-74
3422207-3	1988	The cleavage at Gly-Trp was rapid and 1-13 G-17 was an important intermediate.	Glycine	16-19	PBX homeobox 2	Homo sapiens	43-47
11123375-3	2001	Allosteric interactions with polyamines, Mg(2+), Zn(2+), glutamate, glycine, and their antagonists were consistent with NMDA receptors with NR2B subtype pharmacology.	Glycine	68-75	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	140-144
11118328-1	2000	We describe the genes for three new glycine-rich antimicrobial peptides in Drosophila, two attacins (AttC and AttD) and one diptericin (DptB).	Glycine	36-43	Diptericin A	Drosophila melanogaster	124-134
14627824-4	2003	Our analysis demonstrated that pol lambda Phe506Arg/Gly mutants possess very low polymerase and terminal transferase activities as well as greatly reduced abilities for processive DNA synthesis and for carrying on translesion synthesis past an abasic site.	Glycine	52-55	DNA nucleotidylexotransferase	Homo sapiens	96-116
3337238-3	1988	Unlike gastrin, glycine-extended precursors of gastrin (G-Gly) increased abruptly in the first day of life but thereafter increased at a steady state.	Glycine	16-23	gastrin	Rattus norvegicus	47-54
14650112-1	2003	BACKGROUND: It has been argued that arginine replacement in locus 16 (Arg16) of beta 2 adrenergic receptor with glycin (Gly16) increases asthma severity, while glutamin replacement in locus 27 (Gln27) with glutamic acid (Glu27) decreases it.	Glycine	112-118	adrenoceptor beta 2	Homo sapiens	80-106
14604538-3	2003	Considering 3-D structures of heavy and light chain variable region gene of anti-CD16 antibody, a novel linker peptide PT7 (i.e. Gly(3)SerAla(3)) was designed.	Glycine	129-132	Fc gamma receptor IIIa	Homo sapiens	81-85
14604538-3	2003	Considering 3-D structures of heavy and light chain variable region gene of anti-CD16 antibody, a novel linker peptide PT7 (i.e. Gly(3)SerAla(3)) was designed.	Glycine	129-132	zinc finger protein 79	Homo sapiens	119-122
10991943-5	2000	A strong interaction between the TIMP-2 C domain (Glu(153)-Pro(221)) and the gelatinase A hemopexin C domain (Gly(446)-Cys(660)) was demonstrated by the yeast two-hybrid system.	Glycine	110-113	TIMP metallopeptidase inhibitor 2	Homo sapiens	33-39
11063567-1	2000	Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	156-163	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	0-31
11063567-1	2000	Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate.	Glycine	156-163	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	33-37
11063567-12	2000	This structure suggests that only two of the four catalytic sites on SHMT are catalytically competent and that the cSHMT-glycine-5-formylTHF ternary complex is an intermediate state analogue of the catalytic complex associated with serine and glycine interconversion.	Glycine	121-128	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	69-73
2466737-6	1988	The vitronectin receptor is involved in the adhesion of endothelial cells to Arg-Gly-Asp-containing immobilized proteins such as vitronectin, fibrinogen, and von Willebrand factor.	Glycine	81-84	vitronectin	Homo sapiens	4-15
11053128-8	2000	Mutation of two lysine residues in the outer vestibule of Kv2.1 (K356 and K382), to smaller, uncharged residues (glycine and valine, respectively), completely abolished K(+)-dependent potentiation that was not associated with inactivation.	Glycine	113-120	potassium voltage-gated channel subfamily B member 1	Homo sapiens	58-63
12923815-3	2003	An increase in extracellular glycine concentration by treatment with a glycine transporter 1 (GlyT1)-selective inhibitor, NFPS ethyl ester, significantly decreased the cerebellar localization of [(11)C]L-703,717 in rats.	Glycine	29-36	solute carrier family 6 member 9	Rattus norvegicus	71-92
12923815-3	2003	An increase in extracellular glycine concentration by treatment with a glycine transporter 1 (GlyT1)-selective inhibitor, NFPS ethyl ester, significantly decreased the cerebellar localization of [(11)C]L-703,717 in rats.	Glycine	29-36	solute carrier family 6 member 9	Rattus norvegicus	94-99
2466737-6	1988	The vitronectin receptor is involved in the adhesion of endothelial cells to Arg-Gly-Asp-containing immobilized proteins such as vitronectin, fibrinogen, and von Willebrand factor.	Glycine	81-84	vitronectin	Homo sapiens	129-140
11052087-5	2000	Incorporation of these furanoid sugar amino acids into Leu-enkephalin replacing its Gly-Gly portion gave analogues 8-11.	Glycine	84-87	prodynorphin	Mus musculus	55-69
3693352-1	1987	Peptides containing the tripeptide sequence Arg-Gly-Asp can duplicate or inhibit the cell attachment-promoting effects of fibronectin and vitronectin.	Glycine	48-51	vitronectin	Homo sapiens	138-149
11052087-5	2000	Incorporation of these furanoid sugar amino acids into Leu-enkephalin replacing its Gly-Gly portion gave analogues 8-11.	Glycine	88-91	prodynorphin	Mus musculus	55-69
10851234-7	2000	By combining these methods, we showed that Nsp3 is phosphorylated on serine residues 320, 327, 332, 335, 356, 359, 362, and 367, and is heavily phosphorylated on peptide Gly(338)-Lys(415), which carries 7-12 phosphates distributed over its 13 potential phosphorylation sites.	Glycine	170-173	SH2 domain containing 3C	Homo sapiens	43-47
14568540-1	2003	Crystal structures of P1 Gly, Val, Leu and Phe bovine pancreatic trypsin inhibitor (BPTI) variants in complex with two serine proteinases, bovine trypsin and chymotrypsin, have been determined.	Glycine	25-28	spleen trypsin inhibitor I	Bos taurus	84-88
14568540-5	2003	The more polar interior of the S1 site of trypsin is reflected by a much higher order of the solvent network in the empty pocket of the enzyme, as is observed in the complexes of the two enzymes with the P1 Gly BPTI variant.	Glycine	207-210	spleen trypsin inhibitor I	Bos taurus	211-215
14616374-10	2003	However, delineation of glycine substitutions should prompt comprehensive COL7A1 gene sequencing in the affected individual, as well as clinical assessment of parents and mutation screening in parental DNA, if the true mode of inheritance is to be established correctly.	Glycine	24-31	collagen type VII alpha 1 chain	Homo sapiens	74-80
14580160-5	2003	The activity of prolidase I against glycylproline was enhanced strongly by glycine and MnCl2, but not activated in the absence of MnCl2.	Glycine	75-82	peptidase D	Homo sapiens	16-25
3435452-3	1987	Secreted mucin (SM) differed from intracellular mucin (IM) by having a higher proportion of "minor" mucin amino acids (aspartic acid, glutamic acid, glycine and alanine) and a lower proportion of "major" amino acids (serine, proline and threonine).	Glycine	149-156	solute carrier family 13 member 2	Rattus norvegicus	9-14
14580160-6	2003	The activity of prolidase II against methionylproline was enhanced three-fold in the presence of glycine and MnCl2, but its activity against glycylproline was very low even in the presence of MnCl2.	Glycine	97-104	peptidase D	Homo sapiens	16-25
14580160-8	2003	The activity of prolidase II against methionylproline in all erythrocytes, of normal humans and of patients, was strongly activated by the addition of glycine with MnCl2 but suppressed by the addition of mercaptoethanol.	Glycine	151-158	peptidase D	Homo sapiens	16-25
14557466-2	2003	The goal of the present study was to assess the association between the Gly(16)--&gt;Arg(16) and Gln(27)--&gt;Glu(27) polymorphisms of the beta(2)-adrenergic receptor and metabolic syndrome.	Glycine	72-75	adrenoceptor beta 2	Homo sapiens	139-166
3118192-2	1987	When the glycine residue at position 10, 13, or 15 was substituted with valine, the viral rasH product p21 lost its GTP-binding and autokinase activities.	Glycine	9-16	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	103-106
12915465-4	2003	The first mutation, a T-->G transversion in codon 64, is predicted to change a conserved cysteine residue to glycine in the RING finger domain of the 1863 amino acid BRCA1 protein.	Glycine	109-116	BRCA1 DNA repair associated	Homo sapiens	166-171
10969139-0	2000	A synthetic glycine-extended bombesin analogue interacts with the GRP/bombesin receptor.	Glycine	12-19	gastrin releasing peptide	Rattus norvegicus	66-69
10969139-1	2000	alpha-amidation of a peptide (which takes place from a glycine-extended precursor) is required to produce biologically active amidated hormones, such as gastrin-releasing peptide (GRP)/Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH(2) (bombesin).	Glycine	55-62	gastrin releasing peptide	Rattus norvegicus	153-178
10969139-1	2000	alpha-amidation of a peptide (which takes place from a glycine-extended precursor) is required to produce biologically active amidated hormones, such as gastrin-releasing peptide (GRP)/Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH(2) (bombesin).	Glycine	55-62	gastrin releasing peptide	Rattus norvegicus	180-183
10969139-1	2000	alpha-amidation of a peptide (which takes place from a glycine-extended precursor) is required to produce biologically active amidated hormones, such as gastrin-releasing peptide (GRP)/Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH(2) (bombesin).	Glycine	201-204	gastrin releasing peptide	Rattus norvegicus	153-178
10969139-1	2000	alpha-amidation of a peptide (which takes place from a glycine-extended precursor) is required to produce biologically active amidated hormones, such as gastrin-releasing peptide (GRP)/Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH(2) (bombesin).	Glycine	201-204	gastrin releasing peptide	Rattus norvegicus	180-183
3118192-9	1987	These findings suggest that the glycine-rich consensus sequence is important in controlling p21 activities and that certain mutations may confer to p21 its active conformation without participation of ligand binding.	Glycine	32-39	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	92-95
10851237-4	2000	We show that unique carboxyl-terminal arginine- and glycine-rich domains comprising the last 29 amino acids of SmD1 and the last 32 amino acids of SmD3 are necessary and sufficient for SMN binding.	Glycine	52-59	small nuclear ribonucleoprotein D1 polypeptide	Homo sapiens	111-115
3118192-9	1987	These findings suggest that the glycine-rich consensus sequence is important in controlling p21 activities and that certain mutations may confer to p21 its active conformation without participation of ligand binding.	Glycine	32-39	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	148-151
12954211-2	2003	In this report, we have mutated the two phosphorylated serine residues of the HIV-1 Vpu to glycine residues and have reconstructed a SHIV expressing this nonphosphorylated Vpu (SHIV(S52,56G)).	Glycine	91-98	Vpu	Human immunodeficiency virus 1	84-87
3627975-3	1987	The polymerase chain reaction with Ki-ras specific amplimers revealed a guanosine to adenosine transition at the second position of codon 13, resulting in a substitution of glycine by aspartic acid.	Glycine	173-180	KRAS proto-oncogene, GTPase	Homo sapiens	35-41
12771150-2	2003	A cyclic closed-chain dodecapeptide mimicking the conformation-specific domain of CXCR4 (cDDX4) was prepared in which Gly-Asp, as the dipeptide forming a spacer arm, links the amino and carboxyl termini of the decapeptidyl linear chain (linear DDX4, Asn176 to Ile185) derived from the undecapeptidyl arch (UPA; Asn176 to Cys186) of extracellular loop 2 (ECL-2) in CXCR4.	Glycine	118-121	C-X-C motif chemokine receptor 4	Homo sapiens	82-87
10963786-6	2000	Blocking of GPIIb-IIIa by Arg-Gly-Asp-Ser peptide prevented platelet adhesion to the polystyrene while an extensive adhesion of single platelets to extracellular matrix was observed.	Glycine	30-33	integrin subunit alpha 2b	Homo sapiens	12-17
2440809-11	1987	The binding to group G streptococci, S. aureus, and E. coli is mediated in part through a domain in the S protein containing the sequence Arg-Gly-Asp, whereas a different site is responsible for the binding to group A and C streptococci.	Glycine	142-145	vitronectin	Homo sapiens	104-113
10889339-3	2000	Noxious stimulation (subcutaneous injection of formalin into perioral regions) induced Fos-IR in some of GABA- and Gly-ir neurons.	Glycine	115-118	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	87-90
12888504-0	2003	Lack of sugar discrimination by human Pol mu requires a single glycine residue.	Glycine	63-70	DNA polymerase mu	Homo sapiens	38-44
10839988-2	2000	The amino acid sequences of the stimulator of HIV-1 TAR (Tat-responsive element) RNA-binding protein (SRB) and fibronectin also show the presence of the internal -Gly-Arg-Gly- (-GRG-) sequence, which is potentially methylatable by the methyltransferase.	Glycine	163-166	chaperonin containing TCP1 subunit 4	Homo sapiens	102-105
10848631-5	2000	A homozygous, inactivating missense mutation, G to A at position413, in a codon (GGA) for Gly(138) and resulting in a codon (GAA) for Glu was the genetic cause of peroxisome deficiency of complementation group 17 ZPG208.	Glycine	90-93	alpha glucosidase	Rattus norvegicus	125-128
12885990-4	2003	METHODS: The prevalence of two ADRB2 polymorphisms, Arg16--&gt;Gly and Gln27--&gt;Glu, was examined in 587 smokers chosen from the NHLBI Lung Health Study for having the fastest (n=282) and slowest (n=305) 5 year rate of decline in forced expiratory volume in 1 second (FEV(1); mean DeltaFEV(1) -4.14 and +1.08% predicted/year, respectively).	Glycine	63-66	adrenoceptor beta 2	Homo sapiens	31-36
17186616-4	1987	The core of the 1.175 kb fragment is a repetitive tandemly arranged sequence of 43 units of the hexamer GGA ACT coding for glycine and threonine.	Glycine	123-130	Golgi-localized, gamma-adaptin ear containing, ARF binding protein	Drosophila melanogaster	104-107
12707275-11	2003	These results highlight the crucial role played by Asp-742 in the architecture of the hSPCA1 ion-binding site and reveal a role for Gly-309 in Mn2+ transport selectivity.	Glycine	132-135	ATPase secretory pathway Ca2+ transporting 1	Homo sapiens	86-92
3584243-10	1987	Clustering was also induced by the addition of the GPIIb-IIIa-binding domains of fibrinogen, namely the tetrapeptide Arg-Gly-Asp-Ser on the alpha-chain or the gamma-chain decapeptide gamma 402-411.	Glycine	121-124	integrin subunit alpha 2b	Homo sapiens	51-56
12809490-3	2003	ALY has a conserved RNA binding domain (RBD) flanked by Gly-Arg rich N-terminal and C-terminal sequences.	Glycine	56-59	Aly/REF export factor	Homo sapiens	0-3
10835629-5	2000	CYLD encodes three cytoskeletal-associated-protein-glycine-conserved (CAP-GLY) domains, which are found in proteins that coordinate the attachment of organelles to microtubules.	Glycine	51-58	CYLD lysine 63 deubiquitinase	Homo sapiens	0-4
3596152-0	1987	Secretion and biosynthesis of COOH-terminal glycine extended progastrin (gastrin-G) in rat gastric antrum.	Glycine	44-51	gastrin	Rattus norvegicus	64-71
10773347-3	2000	The Arg-Gly-Asp sequence (RGD), is recognized by many integrins, including integrin alphavbeta3 (CD51/61).	Glycine	8-11	integrin subunit alpha V	Homo sapiens	75-95
10773347-4	2000	Coxsackievirus A9 (CAV-9), a human pathogen that has an Arg-Gly-Asp sequence in the VP1 capsid protein, has been known to be one of the many viruses that utilise integrin alphavbeta3 as a receptor.	Glycine	60-63	integrin subunit alpha V	Homo sapiens	162-182
12519093-7	2003	Subjects carrying the Gly/Gly (GG) genotype of the beta(2)-AR G16R polymorphism demonstrated increases in diastolic BP upon adrenaline infusion, whereas diastolic BP was decreased in the other genotype groups.	Glycine	22-25	adrenoceptor beta 2	Homo sapiens	51-61
12519093-7	2003	Subjects carrying the Gly/Gly (GG) genotype of the beta(2)-AR G16R polymorphism demonstrated increases in diastolic BP upon adrenaline infusion, whereas diastolic BP was decreased in the other genotype groups.	Glycine	26-29	adrenoceptor beta 2	Homo sapiens	51-61
12581645-1	2003	The mRNA nuclear export function of Tap/NXF1 requires interactions with nuclear pore proteins (nucleoporins) that contain characteristic Phe-Gly repeats based on FG, GLFG or FxFG cores separated by hydrophilic linkers.	Glycine	141-144	nuclear RNA export factor 1	Homo sapiens	36-39
12581645-1	2003	The mRNA nuclear export function of Tap/NXF1 requires interactions with nuclear pore proteins (nucleoporins) that contain characteristic Phe-Gly repeats based on FG, GLFG or FxFG cores separated by hydrophilic linkers.	Glycine	141-144	nuclear RNA export factor 1	Homo sapiens	40-44
3596152-1	1987	The effects of serotonin (5-HT) on gastrin and COOH-terminal glycine extended progastrin (gastrin-G) secretion, biosynthesis of gastrin and gastrin-G, and the effects of gastrin-G on gastric acid secretion were examined in rats.	Glycine	61-68	gastrin	Rattus norvegicus	81-88
10806224-9	2000	Deletion experiments showed that the N-terminal glycine- and arginine-rich region is necessary and sufficient to target AtFbr1 to the nucleolus.	Glycine	48-55	fibrillarin 1	Arabidopsis thaliana	120-126
3596152-1	1987	The effects of serotonin (5-HT) on gastrin and COOH-terminal glycine extended progastrin (gastrin-G) secretion, biosynthesis of gastrin and gastrin-G, and the effects of gastrin-G on gastric acid secretion were examined in rats.	Glycine	61-68	gastrin	Rattus norvegicus	81-88
12244096-6	2002	Furthermore, we find that either of the two arginine/glycine-rich domains of GAR1 can provide for interaction with SMN, but removal of both results in loss of the interaction.	Glycine	53-60	GAR1 ribonucleoprotein	Homo sapiens	77-81
3596152-1	1987	The effects of serotonin (5-HT) on gastrin and COOH-terminal glycine extended progastrin (gastrin-G) secretion, biosynthesis of gastrin and gastrin-G, and the effects of gastrin-G on gastric acid secretion were examined in rats.	Glycine	61-68	gastrin	Rattus norvegicus	81-88
3596152-1	1987	The effects of serotonin (5-HT) on gastrin and COOH-terminal glycine extended progastrin (gastrin-G) secretion, biosynthesis of gastrin and gastrin-G, and the effects of gastrin-G on gastric acid secretion were examined in rats.	Glycine	61-68	gastrin	Rattus norvegicus	81-88
3031652-0	1987	pen repeat sequences are GGN clusters and encode a glycine-rich domain in a Drosophila cDNA homologous to the rat helix destabilizing protein.	Glycine	51-58	Pendulin	Drosophila melanogaster	0-3
12270926-7	2002	TRH-[Gly(4)-Lys(5)-Arg(6)] and TRH-[Gly(4)-Lys(5)] represent approximately 45% of the total TRH-like immunoreactivity in Cpe(fat/fat) mice; they constitute approximately 1% in controls.	Glycine	5-8	thyrotropin releasing hormone	Mus musculus	0-3
12359730-3	2002	Based on amino acid sequence comparisons of the encoded proteins, the KAP genes could be divided into seven high glycine-tyrosine gene families (KAP6-KAP8, and KAP19-KAP22) and four high sulfur gene families (KAP11, KAP13, KAP15, and KAP23).	Glycine	113-120	cyclin dependent kinase inhibitor 3	Homo sapiens	70-73
10910114-1	2000	Previous studies show that glycine transporter-1 (glyt-1) is a consistent membrane marker of adult retinal neurons that are likely to release glycine at their synaptic terminals (Pow, 1998; Vaney et al., 1998; Pow &amp; Hendrickson, 1999).	Glycine	27-34	solute carrier family 6 member 9	Rattus norvegicus	50-56
10910114-12	2000	This temporal pattern of labelling strongly indicates that bipolar cells label for glycine when gap junctions become functional between glycine/glyt-1 immunoreactive amacrine cells and cone bipolar cells.	Glycine	83-90	solute carrier family 6 member 9	Rattus norvegicus	144-150
10836608-0	2000	A de novo glycine substitution mutation in the collagenous domain of COL7A1 in dominant dystrophic epidermolysis bullosa.	Glycine	10-17	collagen type VII alpha 1 chain	Homo sapiens	69-75
2880847-8	1987	The active site of lecithin:cholesterol acyltransferase was identified as serine on position 181 according to its homology with other serine-type esterases which have a common structure of glycine-variable amino acid-active serine-variable amino acid-glycine (Gly-X-Ser-X-Gly) with the variable amino acids disrupting the homology.	Glycine	189-196	lecithin-cholesterol acyltransferase	Homo sapiens	19-55
10836608-4	2000	In this study, we report a novel de novo glycine substitution mutation in COL7A1 in a Chinese female patient presenting with mild DEB.	Glycine	41-48	collagen type VII alpha 1 chain	Homo sapiens	74-80
10733977-5	2000	The Asn, Thr, and Gly residues involved in hydrogen bonding to the DNA bases and sugar oxygens form a relatively rigid motif in TBP.	Glycine	18-21	TATA-box binding protein	Homo sapiens	128-131
12542147-6	2002	Analysis of genotypes and shear force values in both populations revealed a difference between paternal CAPN1 alleles in which the allele encoding isoleucine at position 530 and glycine at position 316 associated with decreased meat tenderness (increased shear force values) relative to the allele encoding valine at position 530 and alanine at position 316 (P &lt; 0.05).	Glycine	178-185	calpain 1	Bos taurus	104-109
12472887-5	2002	PC2-null mice displayed a nine-fold increase of cerebral proCCK concentrations, and a two-fold increase in the concentrations of the processing-intermediate, glycine-extended CCK, whereas the concentrations of transmitter-active (i.e. alpha-amidated and O-sulfated) CCK peptides were reduced (61%).	Glycine	158-165	cholecystokinin	Mus musculus	175-178
12445460-4	2002	Both the N-terminal regulatory domain of annexin XI (Anx11N) and the ALG-2-binding domain of Alix/AIP1 are rich in Pro, Gly, Ala, Tyr and Gln.	Glycine	120-123	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	69-74
2840564-5	1987	Hence, intron 1 interrupts the coding region of the bioactive portion of GRP between the first and second nucleotides for Gly, the 24th amino acid of GRP.	Glycine	122-125	gastrin releasing peptide	Homo sapiens	73-76
12507235-8	2002	RESULTS: Adherent cells on Ti plates, with and without GDP, were significantly reduced in serum-free conditions and the presence of RGDS (Arg-Gly-Asp-Ser) peptides.	Glycine	142-145	ral guanine nucleotide dissociation stimulator	Mus musculus	132-136
3102434-3	1987	Nucleotide sequence analysis of the activated N-ras showed a single G----C point mutation at the first letter of codon 13, resulting in the coding of arginine instead of glycine.	Glycine	170-177	NRAS proto-oncogene, GTPase	Homo sapiens	46-51
12431739-6	2002	The disc Ance also showed endopeptidic activity towards locust tachykinin-1 (LomTK-I) by cleaving the Gly-Val peptide bond, but this enzyme was not the sole endopeptidase activity associated with discs.	Glycine	102-105	Angiotensin converting enzyme	Drosophila melanogaster	9-13
12354619-4	2002	A 3 Na(+)/1 Cl(-)/gly stoichiometry was established for GlyT2a on the basis of a 2 charges/glycine flux ratio and changes in the reversal potential of the transporter current as a function of the extracellular glycine, Na(+) and Cl(-) concentrations.	Glycine	18-21	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	56-61
12354619-4	2002	A 3 Na(+)/1 Cl(-)/gly stoichiometry was established for GlyT2a on the basis of a 2 charges/glycine flux ratio and changes in the reversal potential of the transporter current as a function of the extracellular glycine, Na(+) and Cl(-) concentrations.	Glycine	91-98	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	56-61
12354619-4	2002	A 3 Na(+)/1 Cl(-)/gly stoichiometry was established for GlyT2a on the basis of a 2 charges/glycine flux ratio and changes in the reversal potential of the transporter current as a function of the extracellular glycine, Na(+) and Cl(-) concentrations.	Glycine	210-217	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	56-61
12354619-6	2002	In addition, GlyT2a shows a severe limitation for reverse uptake, which suggests an essential role of GlyT2a in maintaining a high intracellular glycine pool, thus facilitating the refilling of synaptic vesicles by the low affinity, low specificity vesicular transporter VGAT/VIAAT.	Glycine	145-152	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	13-18
10679621-1	2000	Linear Aib-based hexapeptides, of the general formula Ac-Toac-(Aib)(n) -Trp-(Aib)(r) -OtBu [T(Aib)(n) Trp], where n + r = 4, and Toac is a nitroxide spin-labeled C(alpha,alpha)-disubstituted glycine, were investigated by steady-state and time-resolved fluorescence measurements in different solvent media.	Glycine	191-198	ANIB1	Homo sapiens	7-10
10664521-6	2000	Analysis of germline DNA in the proband showed a missense mutation (GGC--&gt;GAC) at codon 305 in exon 7 of the MEN1 gene that predicts an amino acid change from glycine to aspartic acid (G305D).	Glycine	162-169	gamma-glutamylcyclotransferase	Homo sapiens	68-71
12354619-8	2002	Finally, analysis of the pre-steady-state kinetics of GlyT1b and GlyT2a revealed that at the resting potential neuronal transporters are preferentially oriented outward, ready to bind glycine, which suggests a kinetic advantage in the uptake contest.	Glycine	184-191	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	65-70
3550423-1	1987	We characterized the normal (Gly-12) and two mutant (Asp-12 and Val-12) forms of human N-ras proteins produced by Escherichia coli.	Glycine	29-32	NRAS proto-oncogene, GTPase	Homo sapiens	87-92
12372564-5	2002	bisindolylmaleimide I (BIM), a selective inhibitor of protein kinase C (PKC), reduced the potentiating effect of 5-HT on I(Gly); and (5).	Glycine	123-126	protein kinase C, gamma	Rattus norvegicus	72-75
10694221-0	2000	Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters.	Glycine	66-73	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	119-124
10694221-5	2000	Kinetic analysis of the initial rates of glycine uptake by GLYT2a as a function of either glycine, chloride or sodium concentration, in the absence and presence of amoxapine indicated that amoxapine behaved as a competitive inhibitor of both glycine and chloride and a mixed-type inhibitor with respect to sodium.	Glycine	41-48	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	59-64
12372564-8	2002	the potentiation of 5-HT on I(Gly) is mediated by 5-HT(2) receptor and through Ca(2+)-independent PKC intracellular signal transduction pathway; and (2).	Glycine	30-33	protein kinase C, gamma	Rattus norvegicus	98-101
10694221-8	2000	Additionally, the inhibition of the glycine uptake by GLYT2 is suggested to have some role in the sedative and psychomotor side effects of amoxapine.	Glycine	36-43	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	54-59
2430295-1	1986	Cells adhere to vitronectin substrates through a cell surface receptor that recognizes an Arg-Gly-Asp sequence in vitronectin.	Glycine	94-97	vitronectin	Homo sapiens	16-27
12082110-6	2002	Although having no direct effect on PAI-1 activity itself, HKa domain 5 or the peptide Gly(486)-Lys(502) markedly destabilized the VN.PAI-1 complex interaction, resulting in a significant reduction of PAI-1 inhibitory function on plasminogen activators, resembling the effect of VN antibodies that prevent stabilization of PAI-1.	Glycine	87-90	vitronectin	Homo sapiens	131-133
12027806-6	2002	A similar cleavage sequence (Phe-Arg-Pro-Gly downward arrow Ser-Val-Val-Val, where downward arrow signifies the cleavage site) has been reported in human MUC1 and analogous sites are present in human MUC3, MUC12 and MUC17.	Glycine	41-44	mucin 12, cell surface associated	Homo sapiens	206-211
12027806-6	2002	A similar cleavage sequence (Phe-Arg-Pro-Gly downward arrow Ser-Val-Val-Val, where downward arrow signifies the cleavage site) has been reported in human MUC1 and analogous sites are present in human MUC3, MUC12 and MUC17.	Glycine	41-44	mucin 17, cell surface associated	Homo sapiens	216-221
11129431-4	2000	Both intact G-actin and G-actin cleaved by subtilisin between Met-47 and Gly-48 in the DNase 1 binding loop of subdomain 2 were treated with bacterial transglutaminase.	Glycine	73-76	deoxyribonuclease 1	Homo sapiens	87-94
2430295-1	1986	Cells adhere to vitronectin substrates through a cell surface receptor that recognizes an Arg-Gly-Asp sequence in vitronectin.	Glycine	94-97	vitronectin	Homo sapiens	114-125
12383231-8	2002	Electrophysiological analysis of heterologously expressed glycine transporters (GlyT) revealed for GlyT2 zero, and for GlyT1 a modest (&lt; 20%), reduction of glycine uptake in the presence of 5 micro m Zn2+, indicating that prolongation of glycinergic IPSCs by Zn2+ is not due to inhibition of glycine removal from the synaptic cleft.	Glycine	58-65	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	99-104
3736029-9	1986	Glycine absorption was 1.63 +/- 0.31 for the control group and 7.83 +/- 0.62 for the gastrin infused group.	Glycine	0-7	gastrin	Rattus norvegicus	85-92
3736029-10	1986	Thus, in this rat model, intraluminal gastrin infusion was capable of increasing carbohydrate (galactose) absorption 456% (P less than 0.01) and protein (glycine) absorption 480% (P less than 0.01).	Glycine	154-161	gastrin	Rattus norvegicus	38-45
3006923-1	1986	Mutagenesis of glycine 2 of p60src, the transforming protein of Rous sarcoma virus (RSV), yields a protein that is neither myristylated nor bound to cellular membranes.	Glycine	15-22	p60 src	Rous sarcoma virus	28-34
12186556-4	2002	Attachment of the tripeptide Gly-Glu-Glu to the para position of cinnamaldehyde resulted in an inhibitor (Cinn-GEE) of substantially increased potency against all three enzymes (e.g., K(I) = 5.4 microM against PTP1B).	Glycine	29-32	CINN	Homo sapiens	106-110
12186556-4	2002	Attachment of the tripeptide Gly-Glu-Glu to the para position of cinnamaldehyde resulted in an inhibitor (Cinn-GEE) of substantially increased potency against all three enzymes (e.g., K(I) = 5.4 microM against PTP1B).	Glycine	29-32	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	210-215
10750822-1	2000	Previous studies show that glycine transporter-1 (glyt-1) is a consistent membrane marker of adult retinal neurons that are likely to release glycine at their synaptic terminals (Pow, 1998; Vaney et al., 1998; Pow &amp; Hendrickson, 1999).	Glycine	27-34	solute carrier family 6 member 9	Rattus norvegicus	50-56
10750822-12	2000	This temporal pattern of labelling strongly indicates that bipolar cells label for glycine when gap junctions become functional between glycine/glyt-1 immunoreactive amacrine cells and cone bipolar cells.	Glycine	83-90	solute carrier family 6 member 9	Rattus norvegicus	144-150
3023884-2	1986	Nucleotide sequence analysis revealed that activated c-Ki-ras shows a G----T transversion in codon 12 and consequently encodes cysteine instead of glycine in normal rat c-Ki-ras.	Glycine	147-154	KRAS proto-oncogene, GTPase	Rattus norvegicus	53-61
10547195-5	1999	By using an automated DNA sequencer, a K-ras mutation (codon 12, GGT to CGT, Gly to Arg) was detected in the pancreatic tumor tissue taken from the patient, whereas no p53 mutation was detected.	Glycine	77-80	KRAS proto-oncogene, GTPase	Homo sapiens	39-44
12209756-6	2002	K-ras point mutation in codon 12 (GGT to GTT transversion) was detected in lung tissue with interstitial pneumonia, in which ras protein was overexpressed in type II alveolar pneumocytes obtained from 2 of 41 patients with IPF complicated by lung carcinoma, causing amino acid substitution (Gly to Val) in both patients.	Glycine	291-294	KRAS proto-oncogene, GTPase	Homo sapiens	0-5
2420006-3	1986	An affinity matrix made of an insolubilized heptapeptide containing the Arg-Gly-Asp sequence selectively binds the platelet membrane glycoprotein IIb/IIIa from detergent extracts of platelets.	Glycine	76-79	integrin subunit alpha 2b	Homo sapiens	115-149
12145341-3	2002	One of the hFSHR mutations examined in this context was the substitution of a highly conserved aspartate (D581) in TM6 with glycine.	Glycine	124-131	follicle stimulating hormone receptor	Homo sapiens	11-16
10464271-2	1999	Its C-terminal 202 amino acids form a potent glycine/glutamine rich activation domain (GQ domain) that can transactivate reporter genes to levels 5-fold higher than VP16 in several mammalian cell lines.	Glycine	45-52	host cell factor C1	Homo sapiens	165-169
2420006-5	1986	This platelet receptor is related to the previously identified fibronectin and vitronectin receptors in that it recognizes an Arg-Gly-Asp sequence but differs from the other receptors in its wider specificity toward various adhesive proteins.	Glycine	130-133	vitronectin	Homo sapiens	79-90
10525449-1	1999	A new peptide carrier with three-dimensional predetermined structural motif has been constructed by the repetitive Lys-Aib-Gly moiety.	Glycine	123-126	ANIB1	Homo sapiens	119-122
10525449-2	1999	The sequential oligopeptide carrier (SOC(n)), (Lys-Aib-Gly)(n), adopts a distorted 3(10)-helical conformation and the Lys-N(epsilon)H(2) anchoring groups exhibit defined spatial orientations.	Glycine	55-58	ANIB1	Homo sapiens	51-54
11923307-6	2002	Exchanging residues within the substrate binding clamp of AtHAL3a (for example of Gly(179)) enabled the detection of the proposed aminoenethiol intermediate when pantothenoylcysteine was used as substrate.	Glycine	82-85	HAL3-like protein A	Arabidopsis thaliana	58-65
2421767-2	1986	Anti-fibrin antibody 59D8 which had been elicited by immunization with human beta(1-7) peptide, Gly-His-Arg-Pro-Leu-Asp-Lys, binds to human and canine fibrins but not to bovine, ovine, or porcine fibrins.	Glycine	96-99	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	77-85
12071967-4	2002	At the cDNA level, the C-terminus of the extracellular domain of human CNTF-R (amino acids 1-346) was linked via a single glycine residue to the N-terminus of human CNTF (amino acids 1-186).	Glycine	122-129	ciliary neurotrophic factor	Homo sapiens	71-75
10506655-2	1999	The carrier, formed by the repetitive Lys-Aib-Gly moiety, is designed to display a predetermined 3D structure, so that the attached peptides would obtain a defined spatial orientation.	Glycine	46-49	ANIB1	Homo sapiens	42-45
3951985-2	1986	Among the various mutations found we discovered two novel Ki-ras mutations in codon 12: gly to ala and gly to ser.	Glycine	88-91	KRAS proto-oncogene, GTPase	Homo sapiens	58-64
11882663-4	2002	In the PDZ1-beta(2)AR complex, the side chain of asparagine at position -4 in the beta(2)AR peptide forms two additional hydrogen bonds with Gly(30) of PDZ1, which contribute to the higher affinity of this interaction.	Glycine	141-144	adrenoceptor beta 2	Homo sapiens	12-21
11882663-4	2002	In the PDZ1-beta(2)AR complex, the side chain of asparagine at position -4 in the beta(2)AR peptide forms two additional hydrogen bonds with Gly(30) of PDZ1, which contribute to the higher affinity of this interaction.	Glycine	141-144	adrenoceptor beta 2	Homo sapiens	82-91
3951985-2	1986	Among the various mutations found we discovered two novel Ki-ras mutations in codon 12: gly to ala and gly to ser.	Glycine	103-106	KRAS proto-oncogene, GTPase	Homo sapiens	58-64
3511910-2	1986	Partial purification by glycine affinity chromatography separates enzyme from inhibitor to yield a preparation which hydrolyzes angiotensin-1, bradykinin, substance P, atriopeptin-2, enkephalin and Hip-His-Leu.	Glycine	24-31	kininogen 1	Bos taurus	143-153
12009947-1	2002	Three amino acids residues, Arg-Gly-Asp (RGD), in vitronectin and fibronectin show affinity for alpha(V)beta(3) integrins expressed in vascular endothelial cells.	Glycine	32-35	vitronectin	Homo sapiens	50-61
12144064-0	2002	Double heterozygosity for Hb Pyrgos [beta83(EF7)Gly-->Asp] and Hb E [beta26(B8)Glu-->Lys] found in association with alpha-thalassemia.	Glycine	48-51	FAM3 metabolism regulating signaling molecule D	Homo sapiens	44-47
10446133-5	1999	Human ATB(0+) (hATB(0+)) is a novel member of the Na(+)/Cl(-)-dependent neurotransmitter transporter family with the highest sequence similarity to the glycine and proline transporters.	Glycine	152-159	solute carrier family 1 member 5	Homo sapiens	6-12
10446133-5	1999	Human ATB(0+) (hATB(0+)) is a novel member of the Na(+)/Cl(-)-dependent neurotransmitter transporter family with the highest sequence similarity to the glycine and proline transporters.	Glycine	152-159	solute carrier family 1 member 5	Homo sapiens	15-23
10509806-1	1999	We report the production of biologically active recombinant rat Gly-2-Ser-1-POMC1-74 (rrPOMC1-74) in a prokaryotic expression system.	Glycine	64-67	proopiomelanocortin	Rattus norvegicus	76-81
10369661-1	1999	Glutathione synthetase (GS) catalyses the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner.	Glycine	100-107	hepatocyte growth factor-regulated tyrosine kinase substrate	Homo sapiens	24-26
11969422-4	2002	Various types of mass spectrometry were used to analyze MLK3 tryptic peptides separated by C18 reverse-phase HPLC, leading to the identification of Ser(524), Ser(654), Ser(705), Ser(740), Ser(758), Ser(770), Ser(793), and a site found on peptide Ser(11)-Arg(37) within a Gly-rich region as MLK3 phosphorylation sites.	Glycine	271-274	mitogen-activated protein kinase kinase kinase 11	Homo sapiens	56-60
2414098-9	1985	The Arg-Gly-Asp sequence appears to constitute the cell attachment site of vitronectin, since it is in the region where we have previously localized the cell attachment site, its presence correlate with cell attachment activity among the insert-coded polypeptides, and because previous results have shown that synthetic peptides containing the Arg-Gly-Asp sequence inhibit the cell attachment function of vitronectin.	Glycine	348-351	vitronectin	Homo sapiens	75-86
3986189-0	1985	The histidine-rich glycoprotein of serum has a domain rich in histidine, proline, and glycine that binds heme and metals.	Glycine	86-93	histidine rich glycoprotein	Homo sapiens	4-31
4062064-1	1985	The amplitude of both P1 and N1 waves of the cortical evoked potentials are significantly increased by topical application of GABA and taurine but not of glycine.	Glycine	154-161	crystallin gamma F, pseudogene	Homo sapiens	22-31
11939795-13	2002	Together, the data indicate that the region between Gly-160 and the end of the third Kunitz domain contributes to TFPI function by orienting the second Kunitz domain so that it can bind the active site of phospholipid-associated factor Xa prior to prothrombinase assembly and/or by slowing formation of the prothrombinase complex.	Glycine	52-55	coagulation factor X	Homo sapiens	229-238
10362520-4	1999	2-D gel electrophoresis of RNase-treated yeast extracts allowed us to tentatively identify the glycine- and arginine-rich (GAR) domain-containing proteins Gar1, Nop1, Sbp1, and Npl3 as major methyl-acceptors based on their known isoelectric points and apparent molecular weights.	Glycine	95-102	Sbp1p	Saccharomyces cerevisiae S288C	167-171
3918541-0	1985	Comparison of glycine metabolism in mouse lymphoma cells either sensitive or resistant to L-asparaginase.	Glycine	14-21	asparaginase like 1	Mus musculus	90-104
10362520-4	1999	2-D gel electrophoresis of RNase-treated yeast extracts allowed us to tentatively identify the glycine- and arginine-rich (GAR) domain-containing proteins Gar1, Nop1, Sbp1, and Npl3 as major methyl-acceptors based on their known isoelectric points and apparent molecular weights.	Glycine	95-102	mRNA-binding protein NPL3	Saccharomyces cerevisiae S288C	177-181
10439118-4	1999	The two peaks showing -57, and -157 (or 156) Da from ATTR Val30Met corresponded to the -Gly, and -Gly-Pro sequences of ATTR Val30Met from the N-terminal.	Glycine	88-91	transthyretin	Homo sapiens	53-57
11920703-1	2002	The vesicular gamma-aminobutyric acid (GABA) transporter (VGAT), which transports the inhibitory amino acid transmitters GABA and glycine, is localized to synaptic vesicles in axon terminals.	Glycine	130-137	solute carrier family 6 member 12	Rattus norvegicus	58-62
11920703-5	2002	In rat retina, VGAT-immunoreactive cell bodies also contained GABA, glycine, or parvalbumin (PV) immunoreactivity, suggesting vesicular uptake of GABA or glycine by these cells.	Glycine	68-75	solute carrier family 6 member 12	Rattus norvegicus	15-19
11920703-5	2002	In rat retina, VGAT-immunoreactive cell bodies also contained GABA, glycine, or parvalbumin (PV) immunoreactivity, suggesting vesicular uptake of GABA or glycine by these cells.	Glycine	154-161	solute carrier family 6 member 12	Rattus norvegicus	15-19
11920703-12	2002	Taken together, these findings demonstrate VGAT immunoreactivity in both amacrine and horizontal cell processes, suggesting these cells contain vesicles that accumulate GABA and glycine, possibly for vesicular release.	Glycine	178-185	solute carrier family 6 member 12	Rattus norvegicus	43-47
11943764-7	2002	We also found that DNTF-2 interacts directly with Mbo/DNup88, which does not contain phenylalanine-glycine-rich repeats, but has been shown to function in the import of Rel proteins.	Glycine	99-106	Nuclear transport factor-2	Drosophila melanogaster	19-25
10439118-4	1999	The two peaks showing -57, and -157 (or 156) Da from ATTR Val30Met corresponded to the -Gly, and -Gly-Pro sequences of ATTR Val30Met from the N-terminal.	Glycine	88-91	transthyretin	Homo sapiens	119-123
10439118-4	1999	The two peaks showing -57, and -157 (or 156) Da from ATTR Val30Met corresponded to the -Gly, and -Gly-Pro sequences of ATTR Val30Met from the N-terminal.	Glycine	98-101	transthyretin	Homo sapiens	53-57
10439118-4	1999	The two peaks showing -57, and -157 (or 156) Da from ATTR Val30Met corresponded to the -Gly, and -Gly-Pro sequences of ATTR Val30Met from the N-terminal.	Glycine	98-101	transthyretin	Homo sapiens	119-123
3918541-1	1985	Previous work suggested a relationship between glycine metabolism and the effect of L-asparaginase upon tumor cells.	Glycine	47-54	asparaginase like 1	Mus musculus	84-98
11943176-2	2002	Here, we studied in vitro the kinetics of this cleavage by hSKI-1 using an intramolecularly quenched fluorogenic (IQF) peptide, Q-GPC(251-263) [Abz-(251)Asp-Ile-Tyr-Ile-Ser-Arg-Arg-Leu-Leu/Gly-Thr-Phe-Thr(263)-3-NitroTyr-Ala-CONH(2)], containing the identified site.	Glycine	189-192	membrane bound transcription factor peptidase, site 1	Homo sapiens	59-65
3918541-4	1985	Under control conditions, the interconversion rate of glycine and serine via serine hydroxymethyltransferase (SHMT) was higher in sensitive than in resistant cells.	Glycine	54-61	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	77-108
3918541-4	1985	Under control conditions, the interconversion rate of glycine and serine via serine hydroxymethyltransferase (SHMT) was higher in sensitive than in resistant cells.	Glycine	54-61	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	110-114
3918541-11	1985	Also, only sensitive cells appear to compensate for L-asparaginase-induced loss of glycine formation from glyoxylate by increasing glycine synthesis from serine.	Glycine	83-90	asparaginase like 1	Mus musculus	52-66
11895450-1	2002	Histidine ammonia-lyase (EC 4.3.1.3) catalyzes the nonoxidative elimination of the alpha-amino group of histidine using a 4-methylidene-imidazole-5-one (MIO), which is formed autocatalytically from the internal peptide segment 142Ala-Ser-Gly.	Glycine	238-241	histidine ammonia-lyase	Homo sapiens	0-23
11861805-0	2002	Protein kinase C modulation of ethanol inhibition of glycine-activated current in dissociated neurons of rat ventral tegmental area.	Glycine	53-60	protein kinase C, gamma	Rattus norvegicus	0-16
11861805-4	2002	In this report, we investigated the role of protein kinase C (PKC) and protein kinase A (PKA) in ethanol-induced inhibition of glycine-activated current, using whole-cell patch-clamp technique.	Glycine	127-134	protein kinase C, gamma	Rattus norvegicus	44-60
11861805-4	2002	In this report, we investigated the role of protein kinase C (PKC) and protein kinase A (PKA) in ethanol-induced inhibition of glycine-activated current, using whole-cell patch-clamp technique.	Glycine	127-134	protein kinase C, gamma	Rattus norvegicus	62-65
11861805-8	2002	In addition, phorbol-12-myristate-13-acetate (PMA, 100 nM), a PKC activator, markedly inhibited glycine-activated current.	Glycine	96-103	protein kinase C, gamma	Rattus norvegicus	62-65
11882681-3	2002	To examine if protein tyrosine kinases (PTKs) regulate the function of GlyRs, we analysed whole-cell currents activated by applications of glycine to CA1 hippocampal neurons and spinal neurons.	Glycine	139-146	carbonic anhydrase 1	Homo sapiens	150-153
11882681-5	2002	Lavendustin A, an inhibitor of PTKs, depressed glycine-evoked currents (I(Gly)) in CA1 neurons and spinal neurons by 31 % and 40 %, respectively.	Glycine	47-54	carbonic anhydrase 1	Homo sapiens	83-86
11882681-5	2002	Lavendustin A, an inhibitor of PTKs, depressed glycine-evoked currents (I(Gly)) in CA1 neurons and spinal neurons by 31 % and 40 %, respectively.	Glycine	74-77	carbonic anhydrase 1	Homo sapiens	83-86
11882681-6	2002	In contrast, the intracellular application of the exogenous tyrosine kinase, cSrc, enhanced I(Gly) in CA1 neurons by 56 %.	Glycine	94-97	carbonic anhydrase 1	Homo sapiens	102-105
11751879-0	2002	Xaa-Arg-Gly triplets in the collagen triple helix are dominant binding sites for the molecular chaperone HSP47.	Glycine	8-11	serpin family H member 1	Homo sapiens	105-110
11751879-4	2002	We found that the Pro-Arg-Gly triplet forms an HSP47-binding site.	Glycine	26-29	serpin family H member 1	Homo sapiens	47-52
11751879-5	2002	The HSP47 binding was observed only when Arg residues were incorporated in the Yaa positions of the Xaa-Yaa-Gly triplets.	Glycine	108-111	serpin family H member 1	Homo sapiens	4-9
11823543-10	2002	One of the D3 epitopes (RGRGRGMGR) has significant sequence homology with a major antigenic region of Sm D1 (containing a carboxyl-terminal glycine-arginine repeat), and anti-D3 Abs cross-react with this epitope of Sm D1.	Glycine	140-147	small nuclear ribonucleoprotein D1 polypeptide	Homo sapiens	102-107
11860374-0	2002	Glycine-extended gastrin-17 stimulates acid secretion only via CCK-2 receptor-induced histamine release in the totally isolated vascularly perfused rat stomach.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
11860374-3	2002	This study examines the effect of glycine-extended gastrin-17 (Gly-G-17), the main non-amidated gastrin precursor, on gastric acid secretion and histamine release in the totally isolated vascularly perfused rat stomach.	Glycine	34-41	gastrin	Rattus norvegicus	51-58
11860374-4	2002	Glycine-extended gastrin-17 at the concentrations from 0.52 to 520 nmol L(-1) was administered to the totally isolated vascularly perfused rat stomach.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
11860374-8	2002	Glycine-extended gastrin-17 at lower concentrations from 0.52 to 5.2 nmol L(-1) did not stimulate gastric acid output or histamine release, whereas higher concentrations from 52 to 520 nmol L(-1) elicited a concentration-dependent increase in acid secretion and histamine release.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
11860374-10	2002	Glycine-extended gastrin-17 at maximally effective concentration of 520 nmol L(-1) did not augment maximal gastrin stimulated acid secretion or histamine release.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
11843659-0	2002	Toenail dystrophy with COL7A1 glycine substitution mutations segregates as an autosomal dominant trait in 2 families with dystrophic epidermolysis bullosa.	Glycine	30-37	collagen type VII alpha 1 chain	Homo sapiens	23-29
11883703-2	2002	When infected with an adenovirus which expresses rat CCK mRNA, several glycine-extended forms were secreted that co-eluted with CCK 33, 22 and 12.	Glycine	71-78	cholecystokinin	Rattus norvegicus	53-56
11883703-2	2002	When infected with an adenovirus which expresses rat CCK mRNA, several glycine-extended forms were secreted that co-eluted with CCK 33, 22 and 12.	Glycine	71-78	cholecystokinin	Rattus norvegicus	128-131
11835337-5	2002	Sequence analysis of this case showed that AGC (Ser) was mutated to GGC (Gly) in codon 154.	Glycine	73-76	gamma-glutamylcyclotransferase	Homo sapiens	68-71
12785105-2	2002	Its soluble precursor (tropoelastin) has two major types of alternating domains: (1) hydrophilic cross-linked domains rich in Lys and Ala and (2) hydrophobic domains (responsible for elasticity) rich in Val, Pro, and Gly, which often occur in repeats of VPGVG or VGGVG.	Glycine	217-220	elastin	Homo sapiens	23-35
11742067-1	2001	Thioredoxin (Trx), a redox enzyme with a conserved active site (Cys-32-Gly-Pro-Cys-35), is induced and secreted into circulation in response to inflammation.	Glycine	71-74	thioredoxin 1	Mus musculus	0-11
11742067-1	2001	Thioredoxin (Trx), a redox enzyme with a conserved active site (Cys-32-Gly-Pro-Cys-35), is induced and secreted into circulation in response to inflammation.	Glycine	71-74	thioredoxin 1	Mus musculus	13-16
11775126-0	2001	The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin.	Glycine	4-11	adrenoceptor beta 2	Homo sapiens	61-86
11775126-0	2001	The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin.	Glycine	24-31	adrenoceptor beta 2	Homo sapiens	61-86
12369927-2	2001	Similar to other nucleotide binding proteins, dUTPase also consists of a sequence motif rich in glycine residues known as P-loop motif.	Glycine	96-103	Deoxyuridine triphosphatase	Drosophila melanogaster	46-53
12369927-5	2001	One of the main reasons for this limited information is the lack of the three-dimensional structure of a dUTPase enzyme with an ordered Gly-rich P-loop motif with a bound substrate and Mg(2+) ion.	Glycine	136-139	Deoxyuridine triphosphatase	Drosophila melanogaster	105-112
12369927-6	2001	This review presents an insight into the role of Gly-rich P-loop motif in the function of dUTPase as revealed from the crystal structure.	Glycine	49-52	Deoxyuridine triphosphatase	Drosophila melanogaster	90-97
12369927-7	2001	The analysis reveals the Gly-rich P-loop motif of dUTPase to be the longest in terms of its amino-acid composition as compared to other nucleotide binding proteins and exhibit a high-degree of sequence conservation among spectrum of species.	Glycine	25-28	Deoxyuridine triphosphatase	Drosophila melanogaster	50-57
11743809-0	2001	Tumor-promoting effect of GGN-MRP extract from the Maillard reaction products of glucose and glycine in the presence of sodium nitrite in C3H10T1/2 cells.	Glycine	93-100	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	Mus musculus	30-33
11743809-1	2001	GGN-MRP is an extract from the Maillard reaction products of nitrite with glucose and glycine in the Maillard browning system.	Glycine	86-93	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	Mus musculus	4-7
11713266-3	2001	SMN binds preferentially and directly to the symmetrical dimethylarginine (sDMA)-modified arginine- and glycine-rich (RG-rich) domains of SmD1 and SmD3.	Glycine	104-111	small nuclear ribonucleoprotein D1 polypeptide	Homo sapiens	138-142
11779085-2	2001	Integrin alpha(v)beta3 interacts with RGD (Arg-Gly-Asp) sequence-containing proteins in the extracellular matrix.	Glycine	47-50	integrin subunit alpha V	Homo sapiens	0-22
10383749-4	1999	Four patients had a glycine substitution mutation on one COL7A1 allele (G1791E, G2242R, G2369S, and G2713R), a fifth was a compound heterozygote for a splice site mutation (5532 + 1G-to-A) and a single base pair deletion (7786delG), and a sixth patient was heterozygous for an out-of-frame deletion mutation (6863del16).	Glycine	20-27	collagen type VII alpha 1 chain	Homo sapiens	57-63
10325428-1	1999	The Drosophila repressor splicing factor 1 (RSF1) comprises an N-terminal RNA-binding region and a C-terminal domain rich in glycine, arginine and serine residues, termed the GRS domain.	Glycine	125-132	Repressor splicing factor 1	Drosophila melanogaster	15-42
10325428-1	1999	The Drosophila repressor splicing factor 1 (RSF1) comprises an N-terminal RNA-binding region and a C-terminal domain rich in glycine, arginine and serine residues, termed the GRS domain.	Glycine	125-132	Repressor splicing factor 1	Drosophila melanogaster	44-48
10353933-7	1999	RESULTS: We found a polymorphism for UGT1A1 in exon 1; a G--&gt;A transition at nucleotide 211 caused arginine to replace glycine at position 71 of corresponding protein product (G71R).	Glycine	122-129	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	37-43
10233777-0	1999	Dominant dystrophic epidermolysis bullosa (Pasini) caused by a novel glycine substitution mutation in the type VII collagen gene (COL7A1).	Glycine	69-76	collagen type VII alpha 1 chain	Homo sapiens	130-136
10233777-3	1999	Mutation detection of the COL7A1 gene revealed a G--&gt;A transition at nucleotide position 6110 in the mutant allele converting a glycine to glutamic acid (G2037E).	Glycine	131-138	collagen type VII alpha 1 chain	Homo sapiens	26-32
10232406-6	1999	The second case had a single glycine substitution mutation (G2079E) in COL7A1 and had therefore DDEB.	Glycine	29-36	collagen type VII alpha 1 chain	Homo sapiens	71-77
10232408-5	1999	This mutation detection strategy disclosed a G-->A transition at nucleotide position 6,235 which resulted in substitution of a glycine by arginine within the collagenous region of COL7A1.	Glycine	127-134	collagen type VII alpha 1 chain	Homo sapiens	180-186
10095061-7	1999	The encoded amino acid sequence predicts that the MEMA protein has three coiled-coil domains, one glycine loop domain, is very hydrophilic and contains regions rich in glutamine/proline, glutamic acid and serine residues.	Glycine	98-105	pinin, desmosome associated protein	Homo sapiens	50-54
10022120-6	1999	Mutation at a loss-of-function site (Gly-298) in Cbl-b-N disrupts its interaction with Syk.	Glycine	37-40	spleen associated tyrosine kinase	Homo sapiens	87-90
11509571-6	2001	We show that the glycine/arginine-rich domain of fibrillarin is necessary and sufficient for SMN binding and that the region of SMN encoded by exon 3, including the Tudor domain, mediates the binding of fibrillarin.	Glycine	17-24	fibrillarin	Homo sapiens	49-60
3918541-11	1985	Also, only sensitive cells appear to compensate for L-asparaginase-induced loss of glycine formation from glyoxylate by increasing glycine synthesis from serine.	Glycine	131-138	asparaginase like 1	Mus musculus	52-66
11603727-9	2001	Blocking of the beta1-integrin with cyclic-peptides containing the Arg-Gly-Asp sequences and antibodies reduced chondrocyte attachment to Type II collagen by 93%.	Glycine	71-74	integrin subunit beta 1	Homo sapiens	16-30
3918541-12	1985	Alterations in sensitive tumor glycine metabolism may be an important function of L-asparaginase anticancer activity.	Glycine	31-38	asparaginase like 1	Mus musculus	82-96
3856237-3	1985	Construction of chimeric molecules between the transforming and the normal N-ras genes and subsequent biological and sequence analysis of these constructs revealed that the transforming gene was altered by a point mutation changing amino acid 12 of the N-ras protein from glycine to aspartic acid.	Glycine	272-279	NRAS proto-oncogene, GTPase	Homo sapiens	253-258
11544176-4	2001	The previously described trx(Z11) mutation changes a strictly conserved glycine in the SET domain to serine and causes homeotic transformations in the fly.	Glycine	72-79	trithorax	Drosophila melanogaster	25-28
11461829-10	2001	I-LBP showed increasing binding of bile acids in the order taurine-conjugated&gt;glycine-conjugated&gt;unconjugated bile acids.	Glycine	81-88	fatty acid binding protein 6	Homo sapiens	0-5
6442544-6	1984	Multiple forms of bovine pepsin A, which differ in their organic phosphate content (0-3 phosphate group(s) per molecule of enzyme) and whose pIs are lower than 2.5, were also separated using 15-20 mM glycine buffer, pH 2.0, as eluent.	Glycine	200-207	pepsin A	Bos taurus	25-33
11592815-9	2001	A PROSITE search also shows that GLUT10 has lost the SUGAR TRANSPORT 2 pattern (PS00217), a result of the substitution G113S in TMD4, while all other known human GLUTs retain the glycine and the pattern match.	Glycine	179-186	solute carrier family 2 member 10	Homo sapiens	33-39
11526230-11	2001	Mutation of either glycine disrupted DAT expression and function.	Glycine	19-26	solute carrier family 6 member 3	Homo sapiens	37-40
11520357-2	2001	The deduced corazonin preprohormone consists of a nineteen amino acid signal peptide, the actual eleven amino acid corazonin sequence, followed by a Gly serving for amidation, a Lys-Arg processing site and an eighty amino acid corazonin precursor-related peptide.	Glycine	149-152	Corazonin	Drosophila melanogaster	12-21
11457520-8	2001	Production of glycine-extended CCK processing products was evaluated by treatment of media with carboxypeptidase B followed by analysis with a CCK Gly RIA.	Glycine	14-21	carboxypeptidase B1	Homo sapiens	96-114
11415439-2	2001	They contain two and three thioredoxin boxes (Cys-Gly-His-Cys) respectively and, like PDI, may be involved in the folding of nascent proteins.	Glycine	50-53	prolyl 4-hydroxylase subunit beta	Rattus norvegicus	86-89
11571626-4	2001	A polymorphic change (Arg to Gly) at DCC codon 201 is related to advanced colorectal carcinoma and increases in the tumors with absent DCC protein expression.	Glycine	29-32	DCC netrin 1 receptor	Homo sapiens	37-40
11571626-4	2001	A polymorphic change (Arg to Gly) at DCC codon 201 is related to advanced colorectal carcinoma and increases in the tumors with absent DCC protein expression.	Glycine	29-32	DCC netrin 1 receptor	Homo sapiens	135-138
11389828-2	2001	In the familial hypercholesterolemia (FH)-Turku LDL receptor allele, a mutation of glycine 823 residue affects the signal required for basolateral targeting in MDCK cells.	Glycine	83-90	low density lipoprotein receptor	Mus musculus	48-60
11389907-2	2001	Substitution of glycine-91 by site-directed mutagenesis with either aspartate or alanine resulted in a significant decrease in transport activity of GLUT1 expressed in Xenopus oocytes.	Glycine	16-23	solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog	Xenopus laevis	149-154
11319765-3	2001	Two glycine transporters have been cloned: GLYT1, mainly expressed by glial cells and shown to colocalize with NMDA receptors, and GLYT2, exclusively expressed by neurons and colocalized with the inhibitory glycine receptors.	Glycine	4-11	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	131-136
11306716-5	2001	The docking of synthetic compounds bearing C-11beta hydrophobic substituents within the ligand binding pocket of hAR demonstrated that precise positions of the steroid, such as C-11 and C-17, are in close contact with some residues on the receptor, C-11 with Gly 708 and C-17 with Asn705 and Thr877.	Glycine	259-262	endogenous retrovirus group K member 20	Homo sapiens	43-51
11306716-5	2001	The docking of synthetic compounds bearing C-11beta hydrophobic substituents within the ligand binding pocket of hAR demonstrated that precise positions of the steroid, such as C-11 and C-17, are in close contact with some residues on the receptor, C-11 with Gly 708 and C-17 with Asn705 and Thr877.	Glycine	259-262	aldo-keto reductase family 1 member C4	Homo sapiens	43-47
11306716-5	2001	The docking of synthetic compounds bearing C-11beta hydrophobic substituents within the ligand binding pocket of hAR demonstrated that precise positions of the steroid, such as C-11 and C-17, are in close contact with some residues on the receptor, C-11 with Gly 708 and C-17 with Asn705 and Thr877.	Glycine	259-262	aldo-keto reductase family 1 member C4	Homo sapiens	177-181
11331301-1	2001	The P2Y(2) nucleotide receptor (P2Y(2)R) contains the integrin-binding domain arginine-glycine-aspartic acid (RGD) in its first extracellular loop, raising the possibility that this G protein-coupled receptor interacts directly with an integrin.	Glycine	87-94	purinergic receptor P2Y2	Homo sapiens	4-30
11331301-1	2001	The P2Y(2) nucleotide receptor (P2Y(2)R) contains the integrin-binding domain arginine-glycine-aspartic acid (RGD) in its first extracellular loop, raising the possibility that this G protein-coupled receptor interacts directly with an integrin.	Glycine	87-94	purinergic receptor P2Y2	Homo sapiens	32-39
11152678-6	2001	This protein is generated in the endoplasmic reticulum through N-terminal cleavage of pro-BDNF at the Arg-Gly-Leu-Thr(57)- downward arrow-Ser-Leu site.	Glycine	106-109	brain derived neurotrophic factor	Homo sapiens	90-94
11281609-5	2001	Significantly, the Gln-Gly cleavage has been shown to be biologically important in the bacterial degradation of PRPs in saliva, generating bacteria-binding Pro-Gln C-termini.	Glycine	23-26	microseminoprotein beta	Homo sapiens	112-116
11221851-4	2001	Peptidylglycine alpha-amidating monooxygenase (PAM) is the enzyme producing alpha-amidated bioactive peptides from their inactive glycine-extended precursors.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	47-50
11027685-8	2001	These studies reveal specific information about Cyt b membrane topology and structure, namely that gp91phox residues (226)RIVRG(230) and (160)IKNP(163) are closely juxtaposed on extracytoplasmic domains and that predicted helices containing residues Gly(165)-Ile(190) and Ser(200)-Glu(225) are adjacent to each other in the membrane.	Glycine	250-253	mitochondrially encoded cytochrome b	Homo sapiens	48-53
11027685-8	2001	These studies reveal specific information about Cyt b membrane topology and structure, namely that gp91phox residues (226)RIVRG(230) and (160)IKNP(163) are closely juxtaposed on extracytoplasmic domains and that predicted helices containing residues Gly(165)-Ile(190) and Ser(200)-Glu(225) are adjacent to each other in the membrane.	Glycine	250-253	cytochrome b-245 beta chain	Homo sapiens	99-107
11162494-4	2001	However, DEC2, but not DEC1, had alanine and glycine-rich regions in the C-terminal half.	Glycine	45-52	basic helix-loop-helix family member e41	Homo sapiens	9-13
11803977-3	2001	Gly-Gly, Trp-Gly, Gly-Trp, Tpr-Trp and Trp-Trp-Trp were the main reaction products for the experimental mixture glycine + tryptophan and Tpr-Trp and Trp-Trp-Trp for tryptophan.	Glycine	112-119	translocated promoter region, nuclear basket protein	Homo sapiens	27-30
11803977-3	2001	Gly-Gly, Trp-Gly, Gly-Trp, Tpr-Trp and Trp-Trp-Trp were the main reaction products for the experimental mixture glycine + tryptophan and Tpr-Trp and Trp-Trp-Trp for tryptophan.	Glycine	112-119	translocated promoter region, nuclear basket protein	Homo sapiens	137-140
11136715-10	2001	The Gly--&gt;Asp mutation within a highly conserved sequence highlights its importance for GLUT1 function.	Glycine	4-7	solute carrier family 2 member 1	Homo sapiens	91-96
11450847-0	2001	Chromosomal localization, structure, single-nucleotide polymorphisms, and expression of the human H-protein gene of the glycine cleavage system (GCSH), a candidate gene for nonketotic hyperglycinemia.	Glycine	120-127	myosin binding protein H	Homo sapiens	98-107
11727705-5	2001	It is particularly true for human tropoelastin, because its sequence is rich in glycines and prolines, and these residues are frequently met in beta-turns (a beta-turn is made of four consecutive residues which are stabilized by an hydrogen bond).	Glycine	80-88	elastin	Homo sapiens	34-46
11090983-0	2000	Improvement of the viability of cultured rat neurons by the non-essential amino acids L-serine and glycine that upregulates expression of the anti-apoptotic gene product Bcl-w.	Glycine	99-106	Bcl2-like 2	Rattus norvegicus	170-175
11090983-6	2000	L-Ser and Gly upregulated expression of the anti-apoptotic gene product Bcl-w, while they did not affect the expression of Bcl-xL.	Glycine	10-13	Bcl2-like 2	Rattus norvegicus	72-77
11090983-7	2000	The promotion of neuronal survival by L-Ser and Gly may be, at least in part, attributable to the upregulated Bcl-w.	Glycine	48-51	Bcl2-like 2	Rattus norvegicus	110-115
11093941-3	2000	The oatp3-mediated uptake rates and affinities were highest for glycine-conjugated dihydroxy bile acids.	Glycine	64-71	solute carrier organic anion transporter family, member 1A5	Rattus norvegicus	4-9
9974410-2	1999	A point mutation in the encoding region of the methionine synthase gene, which results in substitution of an aspartic acid for a glycine residue (D919G), has been identified in patients of the cblG genetic complementation group; these patients exhibit significantly decreased methionine synthase activity.	Glycine	129-136	5-methyltetrahydrofolate-homocysteine methyltransferase	Homo sapiens	47-66
9974410-2	1999	A point mutation in the encoding region of the methionine synthase gene, which results in substitution of an aspartic acid for a glycine residue (D919G), has been identified in patients of the cblG genetic complementation group; these patients exhibit significantly decreased methionine synthase activity.	Glycine	129-136	5-methyltetrahydrofolate-homocysteine methyltransferase	Homo sapiens	276-295
9924200-1	1999	In the biosynthesis of adrenomedullin (AM), an intermediate form, AM(1-52)-glycine-COOH (iAM), is cleaved from proAM and subsequently processed to a biologically active mature form, AM(1-52)-NH2 (mAM), by enzymatic amidation.	Glycine	75-82	adrenomedullin	Homo sapiens	23-37
9890950-8	1999	We found that Cak1p is tolerant of mutations within its glycine loop region.	Glycine	56-63	cyclin-dependent protein kinase-activating kinase CAK1	Saccharomyces cerevisiae S288C	14-19
9890950-9	1999	Remarkably, Cak1p remains functional even following truncation of its first 31 amino acids, including the glycine loop region and the invariant lysine.	Glycine	106-113	cyclin-dependent protein kinase-activating kinase CAK1	Saccharomyces cerevisiae S288C	12-17
10090430-3	1999	Eptifibatide (Integrilin) is a cyclic heptapeptide inhibitor that contains a modified lysine-glycine-aspartic acid sequence that recognizes the binding site of platelet GP IIb-IIIa, resulting in potent and selective inhibition of its binding to fibrinogen.	Glycine	93-100	integrin subunit alpha 2b	Homo sapiens	169-175
10071784-4	1999	These compounds compete with 3H-DCKA binding to rat brain membranes at equilibrium with nanomolar to low-micromolar affinities, and antagonize glycine-evoked currents in oocytes transfected with wild-type NR1-NR2B.	Glycine	143-150	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	209-213
10195445-5	1999	The insertion of Pro, Gly-Ile or Gly-Pro in this hinge region of L-CA-MA caused retention of both antibacterial and antitumor activity while causing a significant decrease in hemolytic activity.	Glycine	22-25	protein tyrosine phosphatase receptor type C	Homo sapiens	65-69
10195445-5	1999	The insertion of Pro, Gly-Ile or Gly-Pro in this hinge region of L-CA-MA caused retention of both antibacterial and antitumor activity while causing a significant decrease in hemolytic activity.	Glycine	33-36	protein tyrosine phosphatase receptor type C	Homo sapiens	65-69
10544372-8	1999	However, in contralateral CA2 and ipsilateral CA3, glycine levels were significantly higher for both the sham and UVD groups compared to anesthetic controls (p &lt; 0.05).	Glycine	51-58	carbonic anhydrase 3	Cavia porcellus	46-49
11400792-2	1999	G6PD "Mahidol" (163 Gly --&gt; Ser) is the most common variant found in the Thai population.	Glycine	20-23	glucose-6-phosphate dehydrogenase	Homo sapiens	0-4
10022320-2	1998	Two genetic alterations have been identified: the first one is a GGC --&gt; GAT (Gly --&gt; Asp, Asp13p21) mutation at codon 13 in the Ki-ras gene, found in five out of six tumors.	Glycine	81-84	glycine-N-acyltransferase	Homo sapiens	76-79
10022320-2	1998	Two genetic alterations have been identified: the first one is a GGC --&gt; GAT (Gly --&gt; Asp, Asp13p21) mutation at codon 13 in the Ki-ras gene, found in five out of six tumors.	Glycine	81-84	KRAS proto-oncogene, GTPase	Homo sapiens	135-141
9856891-6	1998	HGF increased galactose absorption (106% increase over control, P&lt;.01), glycine absorption (95% increase over control, P&lt;.05), protein content (44% increase over control, P&lt;.01), and DNA content (32% increase over control, P&lt;.01).	Glycine	75-82	hepatocyte growth factor	Rattus norvegicus	0-3
9765407-2	1998	We report here the expression of soluble integrin alphav beta5, which retains the ability to recognize the Ad penton base as well as vitronectin, an Arg Gly Asp (RGD)-containing extracellular matrix protein.	Glycine	153-156	vitronectin	Homo sapiens	133-144
9761791-8	1998	However, unlike the 9G8 splicing factor, SRZ proteins contain a glycine hinge, a unique feature in other splicing factors (SC35 and ASF/SF2), located between the RNA binding domain and the zinc knuckle.	Glycine	64-71	serine and arginine rich splicing factor 1	Homo sapiens	132-139
11227798-3	2000	Gly m Bd 60K is an alpha subunit of beta-conglycinin well known as a major soybean storage protein.	Glycine	0-3	alpha subunit of beta conglycinin	Glycine max	19-52
11070044-4	2000	Systematic mutational analysis of vector-expressed GP-C revealed that the motif R-X (L/I/V)-L(259) (where X stands for L, I, or V) is essential for cleavage of the peptide bond between leucine(259) and glycine(260).	Glycine	202-209	glycophorin C (Gerbich blood group)	Homo sapiens	51-55
6480739-5	1984	Digestions by trypsin and subtilisin established that the polypeptide was a variant form of secretin in which the previously known secretin is extended C-terminally by a glycine residue.	Glycine	170-177	secretin	Homo sapiens	92-100
11062067-9	2000	MKK3, MKK4 and MKK6 all show a strong preference for phosphorylation of the tyrosine residue of the Thr-Gly-Tyr motifs in their known substrates SAPK2a/p38, SAPK3/p38 gamma and SAPK4/p38 delta.	Glycine	104-107	mitogen-activated protein kinase kinase 3	Homo sapiens	0-4
11036023-7	2000	Likewise, certain characteristic structural features of CTX-M enzymes, such as Phe-160, Ser-237, and Arg-276, were observed for BES-1, which, in addition, harbored different residues (Ala-104, Ser-171, Arg-220, Gly-240) and six additional residues at the end of the sequence.	Glycine	211-214	BES-1	Serratia marcescens	128-133
6480739-5	1984	Digestions by trypsin and subtilisin established that the polypeptide was a variant form of secretin in which the previously known secretin is extended C-terminally by a glycine residue.	Glycine	170-177	secretin	Homo sapiens	131-139
9724716-7	1998	To disrupt the RI-RNase A interaction, three RNase A residues (Asp-38, Gly-88, and Ala-109) that form multiple contacts with RI were replaced with arginine.	Glycine	71-74	ribonuclease/angiogenin inhibitor 1	Bos taurus	15-17
21344284-1	1984	The principal fatty acids present whenArthrobacter globiformis is grown on a glycine medium free of normal fatty acids were found to be the C15 and C16 anteiso fatty acids; only a small amount of the normal fatty acids (C14 and C16) were present.	Glycine	77-84	placenta associated 8	Homo sapiens	140-143
9703961-5	1998	This CCK Gly immunoreactive peptide was similar in size to CCK 8, and after treatment with arylsulfatase and carboxypeptidase B, it co-eluted on HPLC with unsulfated CCK 8 Gly.	Glycine	9-12	carboxypeptidase B1	Homo sapiens	109-127
9703961-5	1998	This CCK Gly immunoreactive peptide was similar in size to CCK 8, and after treatment with arylsulfatase and carboxypeptidase B, it co-eluted on HPLC with unsulfated CCK 8 Gly.	Glycine	172-175	carboxypeptidase B1	Homo sapiens	109-127
11097175-1	2000	Bifunctional peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes the copper-, ascorbate-, and O2-dependent cleavage of C-terminal glycine-extended peptides, N-acylglycines, and the bile acid glycine conjugates to the corresponding amides and glyoxylate.	Glycine	21-28	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	60-63
11097175-1	2000	Bifunctional peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes the copper-, ascorbate-, and O2-dependent cleavage of C-terminal glycine-extended peptides, N-acylglycines, and the bile acid glycine conjugates to the corresponding amides and glyoxylate.	Glycine	140-147	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	13-58
11097175-1	2000	Bifunctional peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes the copper-, ascorbate-, and O2-dependent cleavage of C-terminal glycine-extended peptides, N-acylglycines, and the bile acid glycine conjugates to the corresponding amides and glyoxylate.	Glycine	140-147	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	60-63
6329265-1	1984	Conglutinin is a bovine plasma protein which is relatively large and asymmetric with elevated contents of glycine and, to some extent, proline.	Glycine	106-113	conglutinin	Bos taurus	0-11
11142768-0	2000	Glycine substitution mutations by different amino acids in the same codon of COL7A1 lead to heterogeneous clinical phenotypes of dominant dystrophic epidermolysis bullosa.	Glycine	0-7	collagen type VII alpha 1 chain	Homo sapiens	77-83
11142768-4	2000	Interestingly, we found that both cases were caused by a missense glycine substitution mutation by different amino acids in the same codon of COL7A1 (G2028R and G2028A).	Glycine	66-73	collagen type VII alpha 1 chain	Homo sapiens	142-148
10998238-1	2000	Integrin alpha(V)beta(3) plays a crucial role in angiogenesis, apoptosis, and bone remodeling, mainly by interacting with matrix proteins through recognition of an Arg-Gly-Asp (RGD) motif.	Glycine	168-171	integrin subunit alpha V	Homo sapiens	0-24
9730366-7	1998	Amplification of the beta-globin exon 2 and nucleotide sequencing revealed a GAT--&gt;GGT mutation in codon 52 corresponding to an Asp--&gt;Gly replacement.	Glycine	140-143	glycine-N-acyltransferase	Homo sapiens	77-80
9624176-6	1998	A glycine residue (Gly711) adjacent to the Y712SPL motif is also important for binding to mu 2/AP-2 and internalization.	Glycine	2-9	transcription factor AP-2 alpha	Homo sapiens	95-99
6695174-2	1984	As a consequence, arginine instead of the normal glycine is incorporated into the K-ras-coded p21 proteins at amino acid position 12.	Glycine	49-56	KRAS proto-oncogene, GTPase	Homo sapiens	82-87
9656995-7	1998	Site-directed mutagenesis of the Cys-1151 residue (one of the catalytic dyad residues of the viral protease) and of the Gly-1300 residue (the viral protease cleavage site) abrogated protease activity and p200 precursor cleavage, respectively.	Glycine	120-123	AT-rich interaction domain 2	Homo sapiens	204-208
10981555-1	2000	Human adrenomedullin (AM) precursor is converted to glycine-extended AM (AM-Gly), an inactive intermediate form of AM.	Glycine	52-59	adrenomedullin	Homo sapiens	6-20
10947972-7	2000	We find that the caspases show an unexpected degree of discrimination in the P(1)" position, with a general preference for small amino acid residues such as alanine, glycine and serine, with glycine being the preferred substituent.	Glycine	166-173	crystallin gamma F, pseudogene	Homo sapiens	77-81
10947972-7	2000	We find that the caspases show an unexpected degree of discrimination in the P(1)" position, with a general preference for small amino acid residues such as alanine, glycine and serine, with glycine being the preferred substituent.	Glycine	191-198	crystallin gamma F, pseudogene	Homo sapiens	77-81
6363409-11	1984	Also noted in this report are two corrections to the DNA sequence of wild type SSB, one of which places glycine (codon GGC) at residue 133 rather than serine as previously reported (Sancar, A., Williams, K. R., Chase, J. W., and Rupp, W. D. (1981) Proc.	Glycine	104-111	single-stranded DNA-binding protein	Escherichia coli	79-82
10825173-3	2000	The tropoelastin-binding site was localized to a region beginning at the glycine-rich and proline-rich regions of fibrillin-2 and fibrillin-1, respectively, and continuing through the second 8-cysteine domain.	Glycine	73-80	elastin	Homo sapiens	4-16
9586664-6	1998	Mutations of Ki-ras codon 12 (wild type = GGT = glycine) or codon 13 (wild type = GGC = glycine) were detected in 37.7% of the tumors; 80.8% (584 of 723) of all the specified mutations occurred in codon 12, and 78.1% (565 of 723) of all the specified mutations were at the second base of either codon.	Glycine	48-55	KRAS proto-oncogene, GTPase	Homo sapiens	13-19
9535892-9	1998	We mutated each of these conserved Asp residues to Gly individually and in pairs in Gbeta and in Sec13, a yeast WD repeat protein involved in vesicular traffic, and then analyzed the ability of the mutant proteins to fold in vitro and in COS-7 cells.	Glycine	51-54	GTPase-activating protein SEC13	Saccharomyces cerevisiae S288C	97-102
9525933-6	1998	Homogenates of nematodes and immunopurified preparations of the recombinant GLY proteins demonstrated that worms express functional ppGaNTase enzymes (GLY-3, GLY-4, GLY-5A, GLY-5B, and GLY-5C), which can O-glycosylate mammalian apomucin peptide sequences in vitro.	Glycine	76-79	Polypeptide N-acetylgalactosaminyltransferase 3	Caenorhabditis elegans	151-156
10891082-11	2000	The ability of PHM to metabolize PBA suggests that the physiological functions of PHM may include the hydroxylation of substrates other than those containing terminal glycines.	Glycine	167-175	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	82-85
6202912-5	1984	Gly at a concentration of 20 mM produced significant inhibition of exocrine secretion evoked by ACh (50 nM) or GRP (36 pM).	Glycine	0-3	gastrin releasing peptide	Rattus norvegicus	111-114
10748065-6	2000	Alanine mutagenesis within this motif demonstrated that the critical amino acids of triadin binding to calsequestrin are the even-numbered residues Lys(210), Lys(212), Glu(214), Lys(216), Gly(218), Gln(220), Lys(222), and Lys(224).	Glycine	188-191	triadin	Homo sapiens	84-91
10872649-1	2000	BACKGROUND AND OBJECTIVES: The most common polymorphisms of the human beta2-adrenergic receptor--Arg16--&gt;Gly and Gln27--&gt;Glu--are associated with alterations in beta2-adrenergic receptor responses, both in vitro and in vivo.	Glycine	108-111	adrenoceptor beta 2	Homo sapiens	70-95
10872649-5	2000	A polymerase chain reaction-based single-stranded conformational polymorphism method with direct sequencing of the bands of interest was used to detect the two frequently occurring beta2-adrenergic receptor variants (Arg16--&gt;Gly, Gln27--&gt;Glu).	Glycine	228-231	adrenoceptor beta 2	Homo sapiens	181-206
9790257-7	1998	The patient was revealed to be heterozygous for a missense mutation G370C, changing codon 370 (GGC) encoding Gly to TGC encoding Cys, but his parents did not have the G370C mutation.	Glycine	109-112	gamma-glutamylcyclotransferase	Homo sapiens	95-98
6462665-2	1984	Glyoxylic acid reacted with ammonia to form N-oxalylglycine, which gave glycine in a 5-39% yield after hydrolysis with 6N HC1.	Glycine	52-59	CYCS pseudogene 39	Homo sapiens	122-125
9621565-3	1998	DNA sequencing revealed that two amino acid substitutions, namely, Ser (TCG)-83--&gt;Leu (TTG) and Asp (GAC)-87--&gt;Gly (GGC), had occurred in the gyrA of all 3 strains isolated from the patients.	Glycine	117-120	gamma-glutamylcyclotransferase	Homo sapiens	122-125
10788509-1	2000	The neuronal glycine transporter GLYT2 takes up glycine from the extracellular space by an electrogenic process where this neurotransmitter is co-transported with sodium and chloride ions.	Glycine	13-20	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	33-38
10788509-2	2000	We report in this paper that tyrosine at position 289 of GLYT2a is crucial for ion coupling, glycine affinity and sodium selectivity, stressing the essential role played by this residue of transmembrane domain III in the mechanism of transport.	Glycine	93-100	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	57-62
6484303-2	1984	1.5 and 3% of Maillard"s reaction products (MRP), prepared by heating glycine and glucose, were incorporated ino a semi-synthetic diet.	Glycine	70-77	ATP binding cassette subfamily C member 2	Rattus norvegicus	14-42
10725382-8	2000	In the recessive sos2-5 allele, a conserved glycine residue in the kinase catalytic domain is changed to glutamate.	Glycine	44-51	Protein kinase superfamily protein	Arabidopsis thaliana	17-21
9568289-1	1998	A novel hexapeptide, H-Pro-Ser-Nva-Gly-Asp-Trp-OH 6, a specific antagonist of platelet fibrinogen receptor (GpIIb/IIIa), was discovered in a structure-activity relationship (SAR) study where the role of the N-terminal Pro moiety of an RGD-containing peptide, H-Pro-Ser-Arg-Gly-Asp-Trp-OH 1, which is a potent but not specific antagonist toward GpIIb/IIIa integrin, was investigated.	Glycine	35-38	integrin subunit alpha 2b	Homo sapiens	108-113
9568289-1	1998	A novel hexapeptide, H-Pro-Ser-Nva-Gly-Asp-Trp-OH 6, a specific antagonist of platelet fibrinogen receptor (GpIIb/IIIa), was discovered in a structure-activity relationship (SAR) study where the role of the N-terminal Pro moiety of an RGD-containing peptide, H-Pro-Ser-Arg-Gly-Asp-Trp-OH 1, which is a potent but not specific antagonist toward GpIIb/IIIa integrin, was investigated.	Glycine	35-38	integrin subunit alpha 2b	Homo sapiens	344-349
6484303-2	1984	1.5 and 3% of Maillard"s reaction products (MRP), prepared by heating glycine and glucose, were incorporated ino a semi-synthetic diet.	Glycine	70-77	ATP binding cassette subfamily C member 2	Rattus norvegicus	44-47
10713059-7	2000	GPIbalpha-CaM bound with similar affinity to recombinant VWF A1, to multimeric plasma VWF, and to a fragment of dispase-digested plasma VWF (residues Leu(480)/Val(481)-Gly(718)).	Glycine	168-171	glycoprotein Ib platelet subunit alpha	Homo sapiens	0-9
6194822-2	1983	Residues 67 to 75 in myelin basic protein from several species comprise the sequence Thr-His-Tyr-Gly-Ser-Leu-Pro-Gln-Lys that acts as an encephalitogenic determinant in the rabbit.	Glycine	97-100	myelin basic protein	Oryctolagus cuniculus	21-41
10712199-2	2000	The mutant proteins have shown an expanded polyglutamine tract in SCA1, SCA2, MJD/SCA3, SCA6, SCA7, and DRPLA; a glycine-to-arginine substitution was found in SCA6 as well.	Glycine	113-120	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	159-163
9490862-0	1998	Cross-modulation of glycine-activated Cl- channels by protein kinase C and cAMP-dependent protein kinase in the rat.	Glycine	20-27	protein kinase C, gamma	Rattus norvegicus	54-70
6133860-11	1983	The results suggest a potential feedback role for bile ductule gamma-glutamyl transpeptidase, in which free bile acids activate the enzyme to catabolize biliary glutathione and thus increase the pool of amino acid precursors required for conjugation (glycine directly and taurine through cysteine oxidation).	Glycine	251-258	inactive glutathione hydrolase 2	Homo sapiens	63-92
9425025-0	1998	Differential perturbation of intersubunit and interdomain communications by glycine 141 mutation in Escherichia coli CRP.	Glycine	76-83	catabolite gene activator protein	Escherichia coli	117-120
6924862-4	1982	The kallikrein has an unusual amino acid composition: aspartic acid and glutamic acid comprise 40% of the residues; the total number of basic residues is less than 5%; glycine and proline together make up more than 40% of the residues.	Glycine	168-175	kallikrein related peptidase 4	Homo sapiens	4-14
9809654-8	1998	These results provide further evidence that glycine-extended CCK peptides are the immediate precursors of amidated CCK peptides.	Glycine	44-51	cholecystokinin	Mus musculus	115-118
10752624-4	2000	The increase is modest (threefold) for substrates specific for tPA that carry Pro or Gly at P2, but reaches 80-fold for less specific substrates carrying Arg at P2.	Glycine	85-88	chromosome 20 open reading frame 181	Homo sapiens	63-66
10683205-0	2000	Differential effects of ethanol on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters.	Glycine	35-42	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	88-93
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	117-124	myosin binding protein H	Homo sapiens	254-263
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	117-124	myosin binding protein H	Homo sapiens	301-310
10672029-10	2000	P1" Pro, Asp, Lys and Gly slowed the hydrolysis rates of the tomato LAP-A, porcine LAP, and E. coli PepA markedly.	Glycine	22-25	leucine aminopeptidase 1, chloroplastic	Solanum lycopersicum	68-73
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	242-249	myosin binding protein H	Homo sapiens	254-263
10672029-10	2000	P1" Pro, Asp, Lys and Gly slowed the hydrolysis rates of the tomato LAP-A, porcine LAP, and E. coli PepA markedly.	Glycine	22-25	leucine aminopeptidase 1, chloroplastic	Solanum lycopersicum	68-71
7153213-8	1982	The inactivation of the P-protein appears to represent a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation, which is supposed to involve the formation of a ternary complex of P-protein, aminomethyl moiety of glycine and H-protein through a Schiff base linkage of the H-protein-bound amino-methyl moiety with the pyridoxal phosphate of P-protein.	Glycine	242-249	myosin binding protein H	Homo sapiens	301-310
7154837-3	1982	Purified brain angiotensin converting enzyme (EC 3.4.15.1) also converts E7 but a purified metalloendopeptidase acts on both E5 and E7 at the Gly-Phe site.	Glycine	142-145	thimet oligopeptidase 1	Rattus norvegicus	91-111
10722119-0	2000	Hb Siam [alpha15(A13)Gly-->Arg] is a GGT-->CGT mutation in the alpha1-globin gene.	Glycine	21-24	UDP glycosyltransferase 8	Homo sapiens	43-46
9435899-5	1997	Compound 6 (Hpa(SO3H)-Nle-Gly-Trp-Nle-MeAsp-Phe-NH2), derived from moving the N-methyl group from Phe to Asp, decreased CCK-B affinity substantially without affecting CCK-A affinity, giving a compound with 6600-fold selectivity for CCK-A receptors.	Glycine	26-29	cholecystokinin	Rattus norvegicus	120-123
9435899-5	1997	Compound 6 (Hpa(SO3H)-Nle-Gly-Trp-Nle-MeAsp-Phe-NH2), derived from moving the N-methyl group from Phe to Asp, decreased CCK-B affinity substantially without affecting CCK-A affinity, giving a compound with 6600-fold selectivity for CCK-A receptors.	Glycine	26-29	cholecystokinin	Rattus norvegicus	167-170
7070876-0	1982	Glycine cleavage system in ketotic hyperglycinemia: a reduction of H-protein activity.	Glycine	0-7	myosin binding protein H	Homo sapiens	67-76
9399966-3	1997	It has been reported that glycine at codon 16 (Gly-16) is associated with increased agonist-promoted downregulation of the beta2AR as compared with arginine-16 (Arg-16).	Glycine	26-33	adrenoceptor beta 2	Homo sapiens	123-130
9399966-3	1997	It has been reported that glycine at codon 16 (Gly-16) is associated with increased agonist-promoted downregulation of the beta2AR as compared with arginine-16 (Arg-16).	Glycine	47-50	adrenoceptor beta 2	Homo sapiens	123-130
10644771-7	2000	To further explore the function of domain 10, we mutated two charged residues near Gly-499 of ClC-1.	Glycine	83-86	chloride voltage-gated channel 1	Homo sapiens	94-99
7070876-5	1982	Analysing of the individual components of the glycine cleavage system, a marked  decrease in the activity of H-protein was revealed in the livers of the both patients; it (0.2 nmole/mg protein/hr) was only 3-4% of that in controls (4.9-6.3 nmole/mg Protein/hr).	Glycine	46-53	myosin binding protein H	Homo sapiens	109-118
11778498-3	2000	RESULTS: (1) The distribution frequency of genotype beta 2-AR 16 loci: Arg/Arg genotype accounts for 13%, Arg/Gly 76% and Gly/Gly 11%.	Glycine	110-113	adrenoceptor beta 2	Homo sapiens	52-61
11778498-3	2000	RESULTS: (1) The distribution frequency of genotype beta 2-AR 16 loci: Arg/Arg genotype accounts for 13%, Arg/Gly 76% and Gly/Gly 11%.	Glycine	122-125	adrenoceptor beta 2	Homo sapiens	52-61
7070876-6	1982	These findings suggest that the reduction of the glycine cleavage system in the liver of ketotic hyperglycinemia occurs secondarily as speculated previously and is caused mainly by a decrease of H-protein activity.	Glycine	49-56	myosin binding protein H	Homo sapiens	195-204
11778498-3	2000	RESULTS: (1) The distribution frequency of genotype beta 2-AR 16 loci: Arg/Arg genotype accounts for 13%, Arg/Gly 76% and Gly/Gly 11%.	Glycine	122-125	adrenoceptor beta 2	Homo sapiens	52-61
11778498-6	2000	(2) The frequency of genotype beta 2-AR 16 loci in asthmatics: Arg/Arg genotype accounts for 24%, Arg/Gly 45% and Gly/Gly 31%.	Glycine	102-105	adrenoceptor beta 2	Homo sapiens	30-39
9395478-2	1997	Cells adhere to the extracellular matrix proteins fibronectin and tenascin in part by the interaction of certain integrins with the Arg-Gly-Asp (RGD) sequence, displayed on specific FNIII repeats.	Glycine	136-139	tenascin C	Homo sapiens	66-74
6262530-3	1981	In ts-25E, a G leads to T transversion at nucleotide 2883 causes the replacement of Gly (GGC) by Cys (TGC).	Glycine	84-87	gamma-glutamylcyclotransferase	Homo sapiens	89-92
9398220-9	1997	In our study, the SHM1 and SHM2 genes were disrupted singly and in combination to investigate the contributions of the two SHMT isozymes to the production of glycine and one-carbon units required in purine biosynthesis.	Glycine	158-165	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	27-31
9398229-2	1997	When these Trp residues are replaced with Gly in either recombinant fragments or synthetic peptides of CaD, the affinity for CaM is decreased by at least 10-fold, suggesting that both of these residues are important for the interaction of CaD with CaM.	Glycine	42-45	calmodulin 2	Gallus gallus	125-128
9398229-2	1997	When these Trp residues are replaced with Gly in either recombinant fragments or synthetic peptides of CaD, the affinity for CaM is decreased by at least 10-fold, suggesting that both of these residues are important for the interaction of CaD with CaM.	Glycine	42-45	calmodulin 2	Gallus gallus	248-251
11778498-6	2000	(2) The frequency of genotype beta 2-AR 16 loci in asthmatics: Arg/Arg genotype accounts for 24%, Arg/Gly 45% and Gly/Gly 31%.	Glycine	114-117	adrenoceptor beta 2	Homo sapiens	30-39
11778498-6	2000	(2) The frequency of genotype beta 2-AR 16 loci in asthmatics: Arg/Arg genotype accounts for 24%, Arg/Gly 45% and Gly/Gly 31%.	Glycine	114-117	adrenoceptor beta 2	Homo sapiens	30-39
10620706-2	2000	To rationalize the significant role of the N-terminal sequence Arg(37)-Arg(38) of human TH type 1 (hTH1) in determining the efficiency of feedback inhibition, we produced mutants of which the positively charged Arg(37)-Arg(38) site was replaced by electrically neutral Gly and/or negatively charged Glu and analyzed the degree of inhibition of these mutant enzymes by dopamine.	Glycine	269-272	negative elongation factor complex member C/D	Homo sapiens	99-103
7275666-0	1981	Hemoglobin Fannin-Lubbock alpha 2 beta 2 119 (GH2) Gly replaced by Asp in Spain.	Glycine	51-54	growth hormone 2	Homo sapiens	46-49
9356388-14	1997	Modulation of NMDA responses by BDNF was dependent on the concentration of extracellular glycine.	Glycine	89-96	brain-derived neurotrophic factor	Rattus norvegicus	32-36
9356388-15	1997	The most pronounced potentiation by BDNF was observed at low concentrations, whereas no potentiation was observed in saturating concentrations of glycine, suggesting that BDNF may have increased the affinity of the NMDA receptor for glycine.	Glycine	233-240	brain-derived neurotrophic factor	Rattus norvegicus	36-40
9356388-15	1997	The most pronounced potentiation by BDNF was observed at low concentrations, whereas no potentiation was observed in saturating concentrations of glycine, suggesting that BDNF may have increased the affinity of the NMDA receptor for glycine.	Glycine	233-240	brain-derived neurotrophic factor	Rattus norvegicus	171-175
9356388-16	1997	However, the competitive glycine-site antagonist 7-chloro-kynurenic acid blocked the enhancement by BDNF without shifting the dose-inhibition relationship for this antagonist, and Mg2+ consistently depressed the potentiation of NMDA-evoked currents by BDNF, indicating that BDNF does not alter glycine affinity.	Glycine	25-32	brain-derived neurotrophic factor	Rattus norvegicus	100-104
7243744-2	1981	We have verified that the latter two are the G gamma and A gamma globin chains which have respectively glycine or alanine at position 136.	Glycine	103-110	hemoglobin subunit gamma 1	Homo sapiens	45-71
7342337-0	1981	[Haemoglobin Fannin-Lubbock (alpha 2 beta 2 119 (GH2) Gly leads to Asp).	Glycine	54-57	growth hormone 2	Homo sapiens	49-52
9324254-6	1997	Overexpression of a truncated version of Mdj1p, containing the J- and Gly/Phe-rich domains, partially substituted for DnaJ function at high temperature.	Glycine	70-73	Mdj1p	Saccharomyces cerevisiae S288C	41-46
7190836-3	1980	The rates of hydrolysis of the Arg-Gly bond in these peptides by thrombin were measured, and the values of the specificity constant, kcat/KM, were all found to be approximately 2 X 10(-7) [(NIH unit/L)s]-1, similar to that for a peptide (F-3) having an additional Arg residue between Glu- and -NHCH3 of F-4.	Glycine	35-38	coagulation factor II, thrombin	Bos taurus	65-73
9329371-3	1997	We found that a common genomic variation in codon 148 (alanine or glycine) of the paraoxonase-2 gene (PON2) demonstrated a significant association with a variation in fasting plasma glucose (P < 0.0001).	Glycine	66-73	paraoxonase 2	Homo sapiens	82-95
9329371-3	1997	We found that a common genomic variation in codon 148 (alanine or glycine) of the paraoxonase-2 gene (PON2) demonstrated a significant association with a variation in fasting plasma glucose (P < 0.0001).	Glycine	66-73	paraoxonase 2	Homo sapiens	102-106
7190836-6	1980	The active site of thrombin thus appears to interact with a peptide of the size of F-6, with the Phe residue possibly being in close spatial proximity to the Val-Arg-Gly moiety.	Glycine	166-169	coagulation factor II, thrombin	Bos taurus	19-27
7372752-1	1980	With use of an anion-exchange packing, TSK Gel IEX 540 DEAE, for high-performance liquid column chromatography, glycine- and taurine-conjugated bile acids were separated in 10 min and detected with a differential refractometer.	Glycine	112-119	tsukushi, small leucine rich proteoglycan	Homo sapiens	39-42
9325391-4	1997	In addition, 1 microM PACAP6-38 (a PACAP antagonist) inhibited channel activity due to 20 microM NMDA and 1 microM glycine by 66%, and this inhibition was reduced to 13% in the additional presence of 2 nM PACAP38.	Glycine	115-122	adenylate cyclase activating polypeptide 1	Gallus gallus	22-27
7372752-3	1980	The purity of the peaks of glycine- and taurine-conjugated bile acids in human bile was confirmed by enzymatic determinations using 3 alpha-hydroxysteroid:NAD oxidoreductase.	Glycine	27-34	thioredoxin reductase 1	Homo sapiens	159-173
6160570-2	1980	We have verified that the latter two are the G gamma and A gamma globin chains which have respectively glycine or alanine at position 136.	Glycine	103-110	hemoglobin subunit gamma 1	Homo sapiens	45-71
9325160-5	1997	RD1 and RD2 had abundant serine and glycine residues, and proline and serine residues, respectively.	Glycine	36-43	phosphodiesterase 6B	Homo sapiens	0-3
9325160-5	1997	RD1 and RD2 had abundant serine and glycine residues, and proline and serine residues, respectively.	Glycine	36-43	peripherin 2	Homo sapiens	8-11
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	cholecystokinin	Mus musculus	20-23
290994-10	1979	Intracellular pool measurements and systematic alteration of perfusate amino acid composition indicated that the autophagic and proteolytic effects of glucagon are mediated by a hormonally induced depletion of glycine, alanine, glutamate, and glutamine; of these, glutamine alone is the most effective.	Glycine	210-217	glucagon	Rattus norvegicus	151-159
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	carboxypeptidase E	Mus musculus	39-42
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	carboxypeptidase E	Mus musculus	48-51
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	24-27	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	297-300	cholecystokinin	Mus musculus	20-23
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	297-300	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	297-300	cholecystokinin	Mus musculus	148-151
103576-2	1978	The inhibitor has a molecular weight near 68,000 and contains approximately 26% carbohydrate alpha-1-Antichymotrypsin has an amino-terminal arginine and a carboxy-terminal glycine.	Glycine	172-179	serpin family A member 3	Homo sapiens	93-117
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	297-300	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	297-300	cholecystokinin	Mus musculus	148-151
9275097-5	1997	The accumulation of CCK Gly Arg Arg in Cpe(fat)/Cpe(fat) brains provides definitive proof that the dibasic cleavage of the carboxyl terminus of pro CCK occurs on the carboxyl terminal of the dibasic, between the Arg and Ser as well as confirming that amidated CCK 8 in brain originates from CCK 8 Gly Arg Arg rather than from larger amidated peptides like CCK 22 or CCK 33.	Glycine	297-300	cholecystokinin	Mus musculus	148-151
889039-1	1977	Gastrin is released from isolated perfused rat antra in a regular fashion by a variety of stimuli, including acetylcholine, glycine, and calcium.	Glycine	124-131	gastrin	Rattus norvegicus	0-7
9261414-4	1997	We demonstrate here that 2APro directly cleaves the single tyrosine-glycine bond at position 34 of TBP.	Glycine	68-75	TATA-box binding protein	Homo sapiens	99-102
266705-5	1977	A synthetic nonapeptide [C3a-(70-77)-Gly], containing a glycyl instead of an arginyl COOH terminus, was approximately 1% as active as the octapeptide when assayed with smooth muscle.	Glycine	37-40	complement C3	Homo sapiens	25-28
9211355-5	1997	Protective measures known to minimize morphological damage to the mTAL, including hyperoncotic perfusion, perfusion with glycine, or perfusion with a mixture of amino acids, decreased mRNA levels of c-fos and egr-1 in the outer medulla (by 50% and 35%, respectively) and the papilla (by 60 and 30%, respectively).	Glycine	121-128	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	199-204
266705-6	1977	The COOH-terminal 13-residue peptide of C3a, C3a-(65-77), was equal in activity to C3a=(70-77); similarly, C3a-(65-77)-Gly expressed the same activity as C3a-(70-77)Gly.	Glycine	119-122	complement C3	Homo sapiens	40-43
266705-6	1977	The COOH-terminal 13-residue peptide of C3a, C3a-(65-77), was equal in activity to C3a=(70-77); similarly, C3a-(65-77)-Gly expressed the same activity as C3a-(70-77)Gly.	Glycine	119-122	complement C3	Homo sapiens	45-48
266705-6	1977	The COOH-terminal 13-residue peptide of C3a, C3a-(65-77), was equal in activity to C3a=(70-77); similarly, C3a-(65-77)-Gly expressed the same activity as C3a-(70-77)Gly.	Glycine	119-122	complement C3	Homo sapiens	45-48
9188696-5	1997	By contrast, TCKI, but not TCKII, served in vitro as a substrate for recombinant, polyhistidine-tagged N-myristoyltransferase and was myristoylated to high stoichiometries (0.58 +/- 0.14 pmol of myristate/pmol of TCK), in the presence of myristoyl-CoA, on glycine in amide linkage.	Glycine	256-263	creatine kinase, flagellar	Strongylocentrotus purpuratus	13-16
266705-6	1977	The COOH-terminal 13-residue peptide of C3a, C3a-(65-77), was equal in activity to C3a=(70-77); similarly, C3a-(65-77)-Gly expressed the same activity as C3a-(70-77)Gly.	Glycine	119-122	complement C3	Homo sapiens	45-48
266705-6	1977	The COOH-terminal 13-residue peptide of C3a, C3a-(65-77), was equal in activity to C3a=(70-77); similarly, C3a-(65-77)-Gly expressed the same activity as C3a-(70-77)Gly.	Glycine	119-122	complement C3	Homo sapiens	45-48
266705-6	1977	The COOH-terminal 13-residue peptide of C3a, C3a-(65-77), was equal in activity to C3a=(70-77); similarly, C3a-(65-77)-Gly expressed the same activity as C3a-(70-77)Gly.	Glycine	165-168	complement C3	Homo sapiens	40-43
300254-0	1977	Spin-lattice relaxation times for 13C in isotope-enriched glycine accumulated in frog muscle.	Glycine	58-65	spindlin 1	Homo sapiens	0-4
9179600-1	1997	Two membrane-localized transporter proteins (GLYT1 and GLYT2) are responsible for removal of extracellular glycine in the mammalian CNS.	Glycine	107-114	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	55-60
300254-1	1977	Spin-lattice relaxation times (T1"s) of 13C-enriched glycine accumulated in frog muscles were determined at 1 degrees C by the inversion-recovery (180 degrees -tau-90 degree pulse sequence) method and compared with the values obtained in free solution.	Glycine	53-60	spindlin 1	Homo sapiens	0-4
9294860-4	1997	The synaptic action of glycine is terminated by two sodium- and chloride-coupled transporters, GLYT1 and GLYT2, located in the glial plasma membrane and in the presynaptic terminals, respectively.	Glycine	23-30	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	105-110
10696873-5	2000	The differences in the nucleotide sequence within the Fragment 7 between S. typhimurium and S. enteritidis may explain the differential expression of CspA at 37 degrees C. The nucleotide sequence of the open reading frame of S. typhimurium cspA gene showed a single base difference at 816 bp position from a G to a C which altered the amino acid residue from a glycine to an alanine.	Glycine	361-368	cold-shock protein	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	150-154
1017794-5	1976	The deprotection of the alpha-amino group by HCl/acetic acid of Boc-Ile-Cys(SiPr)-Gly-Lys(Z) was accompanied by a disulfide exchange at the cysteine residue.	Glycine	82-85	BOC cell adhesion associated, oncogene regulated	Homo sapiens	64-67
11206584-1	2000	The H-protein is one of the four essential components (H-, L-, P-, and T-proteins) of the mammalian glycine cleavage enzyme complex, the major degradative pathway of glycine.	Glycine	100-107	myosin binding protein H	Homo sapiens	4-13
11206584-1	2000	The H-protein is one of the four essential components (H-, L-, P-, and T-proteins) of the mammalian glycine cleavage enzyme complex, the major degradative pathway of glycine.	Glycine	166-173	myosin binding protein H	Homo sapiens	4-13
9238094-7	1997	This DNA change results in the nonconservative substitution of a valine for the normally encoded glycine at amino acid 15 of the MP19 polypeptide.	Glycine	97-104	lens intrinsic membrane protein 2	Mus musculus	129-133
9184125-4	1997	The neurotoxicity caused by glycine occurred in all regions of hippocampal cultures but was most marked in area CA1.	Glycine	28-35	carbonic anhydrase 1	Homo sapiens	112-115
9184125-5	1997	There was significant CA1 neuronal damage in cultures exposed to 10 mM glycine for 30 min or longer (P &lt; 0.01) or those exposed to 4 mM glycine for 24 h compared to control cultures (P &lt; 0.01).	Glycine	71-78	carbonic anhydrase 1	Homo sapiens	22-25
9184125-5	1997	There was significant CA1 neuronal damage in cultures exposed to 10 mM glycine for 30 min or longer (P &lt; 0.01) or those exposed to 4 mM glycine for 24 h compared to control cultures (P &lt; 0.01).	Glycine	139-146	carbonic anhydrase 1	Homo sapiens	22-25
10620140-0	2000	Combination of novel premature termination codon and glycine substitution mutations in COL7A1 leads to moderately severe recessive dystrophic epidermolysis bullosa.	Glycine	53-60	collagen type VII alpha 1 chain	Homo sapiens	87-93
15637-4	1976	The specificity of elastase is probably the same, since in elastin both enzymes hydrolyze the peptide bonds, formed by the NH2-group of glycine and alanine residues, found in elastin in large amounts.	Glycine	136-143	elastin	Homo sapiens	59-66
10593949-0	1999	Association of two nuclear proteins, Npw38 and NpwBP, via the interaction between the WW domain and a novel proline-rich motif containing glycine and arginine.	Glycine	138-145	polyglutamine binding protein 1	Homo sapiens	37-42
15637-4	1976	The specificity of elastase is probably the same, since in elastin both enzymes hydrolyze the peptide bonds, formed by the NH2-group of glycine and alanine residues, found in elastin in large amounts.	Glycine	136-143	elastin	Homo sapiens	175-182
959480-1	1976	Model experiments with two structurally different proteins (alcohol dehydrogenase and salmine) show that glycine, alanine, and tyrosine are by far more frequently involved in photochemically induced cross-link formations with DNA than is cysteine.	Glycine	105-112	aldo-keto reductase family 1 member A1	Homo sapiens	60-81
10574911-10	1999	Further, it has shown that the interaction of HSP47 with the substrate peptides is abolished by prolyl 4-hydroxylation of the second Pro residues in Pro-Pro-Gly triplets and that the fully prolyl 4-hydroxylated peptide, (Pro-Hyp-Gly)(n), does not interact with HSP47.	Glycine	157-160	serpin family H member 1	Homo sapiens	46-51
10574911-10	1999	Further, it has shown that the interaction of HSP47 with the substrate peptides is abolished by prolyl 4-hydroxylation of the second Pro residues in Pro-Pro-Gly triplets and that the fully prolyl 4-hydroxylated peptide, (Pro-Hyp-Gly)(n), does not interact with HSP47.	Glycine	229-232	serpin family H member 1	Homo sapiens	46-51
9092525-10	1997	N-terminal amino acid sequencing of two fragments derived from soluble elastin indicated that both resulted from cleavages of Gly-Ala peptide bonds located within similar sequences, Pro-Gly-Val-Gly-Gly-Ala-Xaa (where Xaa is Phe or Gly).	Glycine	126-129	elastin	Homo sapiens	71-78
9092525-10	1997	N-terminal amino acid sequencing of two fragments derived from soluble elastin indicated that both resulted from cleavages of Gly-Ala peptide bonds located within similar sequences, Pro-Gly-Val-Gly-Gly-Ala-Xaa (where Xaa is Phe or Gly).	Glycine	186-189	elastin	Homo sapiens	71-78
9092525-13	1997	The present results suggest that LasA is a zinc metalloendopeptidase selective for Gly-Ala peptide bonds within Gly-Gly-Ala sequences in elastin.	Glycine	83-86	elastin	Homo sapiens	137-144
9092525-13	1997	The present results suggest that LasA is a zinc metalloendopeptidase selective for Gly-Ala peptide bonds within Gly-Gly-Ala sequences in elastin.	Glycine	112-115	elastin	Homo sapiens	137-144
9092525-13	1997	The present results suggest that LasA is a zinc metalloendopeptidase selective for Gly-Ala peptide bonds within Gly-Gly-Ala sequences in elastin.	Glycine	112-115	elastin	Homo sapiens	137-144
1236831-4	1975	The low insulin activity (0.4 - 0.6%) as measured by the fat cell test as well as the change in the CD spectrum indicated that the loss of the N-terminal glycine of the A-chain results in fully inactive insulin.	Glycine	154-161	LOC105613195	Ovis aries	203-210
9126601-5	1997	Also, our preparation demonstrated expected biological properties of OPN including adhesion of both endothelial and vascular smooth muscle cells to OPN in a dose- and Arg-Gly-Asp-dependent manner.	Glycine	171-174	secreted phosphoprotein 1	Bos taurus	69-72
9126601-5	1997	Also, our preparation demonstrated expected biological properties of OPN including adhesion of both endothelial and vascular smooth muscle cells to OPN in a dose- and Arg-Gly-Asp-dependent manner.	Glycine	171-174	secreted phosphoprotein 1	Bos taurus	148-151
10563791-2	1999	Peptidylglycine monooxygenase (PHM) carries out the hydroxylation of the alpha-C atom of glycine-extended propeptides, the first step in the amidation of peptide hormones by the bifunctional enzyme peptidyl-alpha-amidating monooxygenase (PAM).	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	31-34
10563791-2	1999	Peptidylglycine monooxygenase (PHM) carries out the hydroxylation of the alpha-C atom of glycine-extended propeptides, the first step in the amidation of peptide hormones by the bifunctional enzyme peptidyl-alpha-amidating monooxygenase (PAM).	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	198-236
10563791-2	1999	Peptidylglycine monooxygenase (PHM) carries out the hydroxylation of the alpha-C atom of glycine-extended propeptides, the first step in the amidation of peptide hormones by the bifunctional enzyme peptidyl-alpha-amidating monooxygenase (PAM).	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	238-241
1176090-7	1975	The decrease in cell viability observed in glycine media could be compensated for by addition of Ca2.	Glycine	43-50	carbonic anhydrase 2	Homo sapiens	97-100
10583163-2	1999	Mutations in the type VII collagen gene (COL7A1) underlie EBD and in a dominant PEB family a glycine substitution mutation has been identified.	Glycine	93-100	collagen type VII alpha 1 chain	Homo sapiens	41-47
9106216-8	1997	The expression of lif in S. carnosus led to an increase in the serine/glycine ratio of the interpeptide bridges of peptidoglycan from 2 to 35%, suggesting that lysostaphin immunity depends on serine incorporation into the interpeptide bridge.	Glycine	70-77	ORF44	Staphylococcus simulans bv. staphylolyticus	18-21
9106216-10	1997	Lif shows similarity to FemA and FemB proteins, which are involved in the biosynthesis of the glycine interpeptide bridge of staphylococcal peptidoglycan.	Glycine	94-101	ORF44	Staphylococcus simulans bv. staphylolyticus	0-3
9324163-6	1997	The CCK-B receptor antagonist L365,260 almost totally blocked MAPK activation in AR42J cells after stimulation with gastrin and glycine-extended gastrin and substantially reduced the activation of both kinases by CCK-8, while the CCK-A receptor antagonist L364,718 was much less effective.	Glycine	128-135	cholecystokinin	Rattus norvegicus	4-7
9324163-6	1997	The CCK-B receptor antagonist L365,260 almost totally blocked MAPK activation in AR42J cells after stimulation with gastrin and glycine-extended gastrin and substantially reduced the activation of both kinases by CCK-8, while the CCK-A receptor antagonist L364,718 was much less effective.	Glycine	128-135	gastrin	Rattus norvegicus	145-152
50603-11	1975	One could comare the levels of frequent and characteristic peptide triplet sequences such as Gly-Pro-Hyp to Gly-Pro-Pro, Gly-Ala-Hyp to Gly-Ala-Pro, or Gly-Pro-Hyl to Gly-Pro-Lys and others for evaluation of hydroxylation throughout the entire molecule or at selected sequences.	Glycine	108-111	megakaryocyte-associated tyrosine kinase	Homo sapiens	160-163
9044045-1	1997	The enzyme N-myristoyl transferase transfers the 14 carbon fatty acid myristate to an N-terminal glycine residue in a small subset of cytoplasmic proteins.	Glycine	97-104	N-myristoyl transferase	Drosophila melanogaster	11-34
9001550-9	1997	RESULTS: K-ras codon 12 mutations representing glycine to valine substitutions were present in 2 of (18%) 11 patients with ductal hyperplasia.	Glycine	47-54	KRAS proto-oncogene, GTPase	Homo sapiens	9-14
10520212-4	1999	One relatively common polymorphism in the methionine synthase gene (D919G) is an A to G transition at bp 2,756, which converts an aspartic acid residue believed to be part of a helix involved in co-factor binding to a glycine.	Glycine	218-225	5-methyltetrahydrofolate-homocysteine methyltransferase	Homo sapiens	42-61
10497166-2	1999	To test whether the factor Xa specificity of allosterically activated antithrombin is encoded in the serpin reactive center loop, we mutated the factor Xa-preferred P2 Gly to the thrombin-preferred P2 Pro.	Glycine	168-171	coagulation factor X	Homo sapiens	145-154
10524541-1	1999	We examined the beta2-adrenergic receptor (beta2AR) polymorphisms (Arg16--&gt;Gly, Gln27--&gt;Glu) and clinical status for 117 asthmatics.	Glycine	78-81	adrenoceptor beta 2	Homo sapiens	43-50
50603-11	1975	One could comare the levels of frequent and characteristic peptide triplet sequences such as Gly-Pro-Hyp to Gly-Pro-Pro, Gly-Ala-Hyp to Gly-Ala-Pro, or Gly-Pro-Hyl to Gly-Pro-Lys and others for evaluation of hydroxylation throughout the entire molecule or at selected sequences.	Glycine	108-111	megakaryocyte-associated tyrosine kinase	Homo sapiens	160-163
10571879-4	1999	The methylenetetra- hydrofolate (CH2-THF) produced during this reaction did not equilibrate with the overall CH2-THF pool, but was almost totally recycled by the mitochondrial serine hydroxymethyltransferase (SHMT) for the synthesis of one serine from a second molecule of glycine.	Glycine	273-280	serine hydroxymethyltransferase 2	Homo sapiens	162-207
13405898-0	1957	Incorporation of C14-labeled glycine and formate by the acid-soluble guanine and adenine nucleotides of rat liver.	Glycine	29-36	anti-Mullerian hormone receptor type 2	Rattus norvegicus	17-20
10582243-9	1999	The C-terminal glycine residue of a novel modifier protein Apg12p, a 186-amino-acid protein, is conjugated to a lysine residue of Apg5p, a 294-amino-acid protein, via an isopeptide bond.	Glycine	15-22	Atg12p	Saccharomyces cerevisiae S288C	59-65
33909912-4	2021	Mechanistically, R406 alleviates Syk / calcineurin (Cn) / nuclear factor of activated T cells (NFAT) signaling-mediated suppression of glycine, serine, and threonine metabolic genes and dependent metabolites.	Glycine	135-142	spleen tyrosine kinase	Mus musculus	33-36
10473590-6	1999	Signaling through the nonpalmitoylated, Gly(341)beta(2)AR mutant was unchanged by SIN-1 treatment.	Glycine	40-43	adrenoceptor beta 2	Homo sapiens	48-57
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	12-15	ANIB1	Homo sapiens	63-66
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	12-15	ANIB1	Homo sapiens	83-86
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	12-15	ANIB1	Homo sapiens	83-86
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	12-15	ANIB1	Homo sapiens	83-86
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	16-19	ANIB1	Homo sapiens	63-66
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	16-19	ANIB1	Homo sapiens	83-86
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	16-19	ANIB1	Homo sapiens	83-86
8946799-2	1996	The central Gly-Gly segment of the helical octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe(1) has been replaced by delta-amino-valeric acid (delta-Ava) residue in the newly designed peptide Boc-Leu-Aib-Val-delta-Ava-Leu-Aib-Val-OMe(2).	Glycine	16-19	ANIB1	Homo sapiens	83-86
10455109-6	1999	Mutation of Ser(319) in TM 7 of hCNT1 to Gly enabled transport of purine nucleosides, whereas concurrent mutation of Gln(320) to Met (which had no effect on its own) augmented this transport.	Glycine	41-44	solute carrier family 28 member 1	Homo sapiens	32-37
33909912-5	2021	Syk inhibition upregulates glycine level and downstream transsulfuration cysteine biosynthesis, promoting cysteine metabolism and cellular hydrogen sulfide (H2 S) production.	Glycine	27-34	spleen tyrosine kinase	Mus musculus	0-3
34015290-4	2021	MAIN METHODS: Induced pluripotent stem cells (iPSCs) were generated from OI patients with glycine substitution mutations in COL1A1 and COL1A2 and developed into mesenchymal stem cells (iPS-MSCs).	Glycine	90-97	collagen type I alpha 1 chain	Homo sapiens	124-130
10428822-6	1999	However, exon 2 of the COL9A3 gene codes for one -Gly-X-Y- triplet less than exon 2 of the COL9A2 gene.	Glycine	50-53	collagen type IX alpha 3 chain	Homo sapiens	23-29
10471037-0	1999	The laminin-derived peptide YIGSR (Tyr-Ile-Gly-Ser-Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID mice.	Glycine	43-46	prolactin regulatory element binding	Homo sapiens	71-76
10375640-5	1999	However, the amino terminal of CBS-1 (residues 23 to 43), which lacks homology to the amino terminal region of gonococcal pilB or pneumococcal MsrA, exhibits significant identity in a stretch of 20 amino acids, with glycine-rich proteins.	Glycine	216-223	methionine sulfoxide reductase B2	Homo sapiens	31-36
10347152-7	1999	Because an important role in the conversion of glyoxylate to glycine has been assigned to peroxisomal SPT/AGT from the studies on primary hyperoxaluria type 1, these results suggest that SPT/AGT in this organelle plays dual roles in the metabolism of glyoxylate and serine.	Glycine	61-68	serine--pyruvate aminotransferase	Oryctolagus cuniculus	102-105
10347152-7	1999	Because an important role in the conversion of glyoxylate to glycine has been assigned to peroxisomal SPT/AGT from the studies on primary hyperoxaluria type 1, these results suggest that SPT/AGT in this organelle plays dual roles in the metabolism of glyoxylate and serine.	Glycine	61-68	serine--pyruvate aminotransferase	Oryctolagus cuniculus	187-190
10397373-2	1999	Propofol and pentobarbitone enhanced agonist (GABA or glycine as appropriate) evoked currents at GABA(A), glycine, and RDL receptors, whereas etomidate and 5alpha3alpha were highly selective for the GABA(A) receptor.	Glycine	54-61	GABA(A) receptor-associated protein L homeolog	Xenopus laevis	97-104
10650340-10	1999	It is concluded that glycine transport by channel catfish brain has much in common with transport by mammalian nervous tissue which is carried out by the membrane carriers GLYT1 and GLYT2.	Glycine	21-28	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	182-187
10090730-4	1999	Like the latter, RSF1 comprises an amino-terminal RRM-type RNA-binding domain, whereas its carboxy-terminal part is enriched in glycine (G), arginine (R), and serine (S) residues (GRS domain).	Glycine	128-135	Repressor splicing factor 1	Drosophila melanogaster	17-21
9950658-2	1999	Small-molecule antagonists of GP IIb/IIIa based on the Arg-Gly-Asp (RGD) sequence show similar benefit, and some of these agents are orally active.	Glycine	59-62	integrin subunit alpha 2b	Homo sapiens	30-36
9882303-6	1999	Using a series of fine mutants in which single amino acids between codons 379 and 386 were changed to glycine, we have found that mutations of Pro379, Glu381, Ser383, or Tyr384 diminish the ability of LMP1 CTAR2 to engage JNK signalling.	Glycine	102-109	PDZ and LIM domain 7	Homo sapiens	201-205
9890950-3	1999	Cak1p lacks the highly conserved glycine loop motif (GXGXXG) that is found in the nucleotide binding fold of virtually all protein kinases and also lacks a number of conserved amino acids found at sites throughout the protein kinase core sequence.	Glycine	33-40	cyclin-dependent protein kinase-activating kinase CAK1	Saccharomyces cerevisiae S288C	0-5
10226523-1	1999	BACKGROUND: Glycine-extended progastrin (G-17-Gly), the immediate biosynthetic precursor to gastrin (G-17), stimulates growth of some gastrointestinal cancers in vitro.	Glycine	12-19	PBX homeobox 2	Homo sapiens	41-45
10226523-1	1999	BACKGROUND: Glycine-extended progastrin (G-17-Gly), the immediate biosynthetic precursor to gastrin (G-17), stimulates growth of some gastrointestinal cancers in vitro.	Glycine	12-19	PBX homeobox 2	Homo sapiens	101-105
10051123-4	1999	CCK-8s, gastrin(1-17) and its glycine-extended precursor G(1-17)-Gly, previously reported to cause proliferation via putative novel sites on AR4-2J and Swiss 3T3 cells, elicited significant dose dependent increases of similar magnitude in [3H]thymidine incorporation over 3 days in serum-free medium of 39 +/- 10% (P &lt; 0.01, n = 20), 37 +/- 8% (P &lt; 0.01, n = 27) and 41 +/- 6% (P &lt; 0.01, n = 36) respectively.	Glycine	30-37	cholecystokinin	Rattus norvegicus	0-3
10051123-4	1999	CCK-8s, gastrin(1-17) and its glycine-extended precursor G(1-17)-Gly, previously reported to cause proliferation via putative novel sites on AR4-2J and Swiss 3T3 cells, elicited significant dose dependent increases of similar magnitude in [3H]thymidine incorporation over 3 days in serum-free medium of 39 +/- 10% (P &lt; 0.01, n = 20), 37 +/- 8% (P &lt; 0.01, n = 27) and 41 +/- 6% (P &lt; 0.01, n = 36) respectively.	Glycine	65-68	cholecystokinin	Rattus norvegicus	0-3
9892210-4	1999	These CD44 variants bind to both the amino- and COOH-terminal portions of OPN independently of the arginine-glycine-aspartic acid sequence, suggesting that multiple domains on OPN can be bound by the CD44 variants.	Glycine	108-115	CD44 molecule (Indian blood group)	Homo sapiens	6-10
10325961-4	1999	Phosphorylation of PLB was measured by reduced mobility of the phosphorylated forms on Tris-glycine gels.	Glycine	92-99	cardiac phospholamban	Oryctolagus cuniculus	19-22
10403510-1	1999	In the biosynthesis of adrenomedullin (AM), glycine-extended AM, an intermediate form (iAM) processed from proAM is converted to AM[1-52]-NH2, the bioactive mature form of AM (mAM), by enzymatic amidation.	Glycine	44-51	adrenomedullin	Homo sapiens	23-37
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	45-52	cholecystokinin	Mus musculus	62-65
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	45-52	cholecystokinin	Mus musculus	67-70
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	45-52	cholecystokinin	Mus musculus	67-70
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	45-52	carboxypeptidase E	Mus musculus	166-169
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	45-52	carboxypeptidase E	Mus musculus	175-178
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	71-74	cholecystokinin	Mus musculus	62-65
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	71-74	cholecystokinin	Mus musculus	67-70
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	71-74	cholecystokinin	Mus musculus	67-70
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	95-98	cholecystokinin	Mus musculus	62-65
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	95-98	cholecystokinin	Mus musculus	67-70
10221600-2	1998	Using an radioimmunoassay (RIA) specific for glycine-extended CCK (CCK Gly), low levels of CCK Gly were detected in control (0.65 ng/g tissue) and were even lower in Cpe(fat)/Cpe(fat) (0.246 ng/g) mice brain extracts.	Glycine	95-98	cholecystokinin	Mus musculus	67-70
10221600-3	1998	After treatment with carboxypeptidase B, the level of CCK Gly in Cpe(fat)/Cpe(fat) in these brain extracts was elevated to 33.5 ng/g, about 51-fold higher than in control.	Glycine	58-61	cholecystokinin	Mus musculus	54-57
10221600-3	1998	After treatment with carboxypeptidase B, the level of CCK Gly in Cpe(fat)/Cpe(fat) in these brain extracts was elevated to 33.5 ng/g, about 51-fold higher than in control.	Glycine	58-61	carboxypeptidase E	Mus musculus	65-68
10221600-3	1998	After treatment with carboxypeptidase B, the level of CCK Gly in Cpe(fat)/Cpe(fat) in these brain extracts was elevated to 33.5 ng/g, about 51-fold higher than in control.	Glycine	58-61	carboxypeptidase E	Mus musculus	74-77
10221600-4	1998	On gel-filtration chromatography and high-performance liquid chromatography (HPLC), this material coeluted with CCK 8 Gly.	Glycine	118-121	cholecystokinin	Mus musculus	112-115
10221600-5	1998	These results demonstrate that CPE is required for the correct processing of arginine- and glycine-extended CCK in all major regions of the mouse brain.	Glycine	91-98	carboxypeptidase E	Mus musculus	31-34
10221600-5	1998	These results demonstrate that CPE is required for the correct processing of arginine- and glycine-extended CCK in all major regions of the mouse brain.	Glycine	91-98	cholecystokinin	Mus musculus	108-111
10221600-6	1998	These results support the hypothesis that CCK 8 Gly is the immediate precursor of CCK 8 amide in mouse brain, not larger amidated forms like CCK 22 or CCK 33.	Glycine	48-51	cholecystokinin	Mus musculus	42-45
10221600-6	1998	These results support the hypothesis that CCK 8 Gly is the immediate precursor of CCK 8 amide in mouse brain, not larger amidated forms like CCK 22 or CCK 33.	Glycine	48-51	cholecystokinin	Mus musculus	82-85
10221600-6	1998	These results support the hypothesis that CCK 8 Gly is the immediate precursor of CCK 8 amide in mouse brain, not larger amidated forms like CCK 22 or CCK 33.	Glycine	48-51	cholecystokinin	Mus musculus	82-85
10221600-6	1998	These results support the hypothesis that CCK 8 Gly is the immediate precursor of CCK 8 amide in mouse brain, not larger amidated forms like CCK 22 or CCK 33.	Glycine	48-51	cholecystokinin	Mus musculus	82-85
9822734-7	1998	Triple labeling for VGAT, GABA, and glycine in the lateral oliva superior revealed a higher expression of VGAT in nerve endings rich in GABA, with or without glycine, than in others rich in glycine only.	Glycine	36-43	solute carrier family 6 member 12	Rattus norvegicus	106-110
9822734-7	1998	Triple labeling for VGAT, GABA, and glycine in the lateral oliva superior revealed a higher expression of VGAT in nerve endings rich in GABA, with or without glycine, than in others rich in glycine only.	Glycine	158-165	solute carrier family 6 member 12	Rattus norvegicus	20-24
9822734-7	1998	Triple labeling for VGAT, GABA, and glycine in the lateral oliva superior revealed a higher expression of VGAT in nerve endings rich in GABA, with or without glycine, than in others rich in glycine only.	Glycine	158-165	solute carrier family 6 member 12	Rattus norvegicus	106-110
9822734-7	1998	Triple labeling for VGAT, GABA, and glycine in the lateral oliva superior revealed a higher expression of VGAT in nerve endings rich in GABA, with or without glycine, than in others rich in glycine only.	Glycine	158-165	solute carrier family 6 member 12	Rattus norvegicus	20-24
9822734-7	1998	Triple labeling for VGAT, GABA, and glycine in the lateral oliva superior revealed a higher expression of VGAT in nerve endings rich in GABA, with or without glycine, than in others rich in glycine only.	Glycine	158-165	solute carrier family 6 member 12	Rattus norvegicus	106-110
9822734-8	1998	Although the great majority of nerve terminals containing GABA or glycine are immunopositive for VGAT, subpopulations of nerve endings rich in GABA or glycine appear to lack the protein.	Glycine	66-73	solute carrier family 6 member 12	Rattus norvegicus	97-101
9855162-8	1998	RESULTS: A G--&gt;T nucleotide change at position 238 in exon 3 of the RPGR gene resulting in a putative substitute of Gly--&gt;Val at codon 60 was shown to segregate with RP in affected males and the carrier state in female heterozygotes in these two families.	Glycine	119-122	retinitis pigmentosa GTPase regulator	Homo sapiens	71-75
9845349-4	1998	When stably expressed in CHO cells, human GlyT2 displays a dose-dependent uptake of glycine with an apparent Km of 108 microM.	Glycine	84-91	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	42-47
9814482-3	1998	These two additional C18 conversions can be catalyzed by CYP11B1 if serine-288 and valine-320 are replaced by the corresponding CYP11B2 residues, glycine and alanine.	Glycine	146-153	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	57-64
9892921-0	1998	A recurrent glycine substitution mutation, G2043R, in the type VII collagen gene (COL7A1) in dominant dystrophic epidermolysis bullosa.	Glycine	12-19	collagen type VII alpha 1 chain	Homo sapiens	82-88
9892921-3	1998	In this study, we identified a patient of Hispanic-Mexican origin with a mild form of DEB, which resulted from a de novo dominant glycine substitution, G2043R, in exon 73 of COL7A1.	Glycine	130-137	collagen type VII alpha 1 chain	Homo sapiens	174-180
9867248-1	1998	The thyrotropin- (TRH) releasing hormone precursor (26 kDa) undergoes proteolytic cleavage at either of two sites, generating N-terminal 15 kDa/9.5 kDa or C-terminal 16.5/10 kDa intermediate forms that are processed further to yield five copies of TRH-Gly and seven non-TRH peptides.	Glycine	252-255	thyrotropin releasing hormone	Mus musculus	18-21
9759731-6	1998	The carboxy-terminal glycine residue of Apg12, a 186-amino-acid protein, is conjugated to a lysine at residue 149 of Apg5, a 294-amino-acid protein.	Glycine	21-28	Atg12p	Saccharomyces cerevisiae S288C	40-45
9721724-4	1998	XenU1 binds not only kainate with high affinity (K(D) 1.2 nM at 25 degrees C), but also the glycine site antagonist 5,7-dichlorokynurenic acid (DCKA).	Glycine	92-99	glutamate receptor KA2 L homeolog	Xenopus laevis	0-5
9721724-8	1998	Only 18% of the binding to the complex has the properties of the NMDA receptor glycine site, the rest being due to switching of the high-affinity kainate site of XenU1 (low-affinity DCKA) to a high-affinity DCKA (low-affinity kainate) conformation.	Glycine	79-86	glutamate receptor KA2 L homeolog	Xenopus laevis	162-167
8967976-4	1996	Inhibition of NR1A/2B receptors is insurmountable with respect to glutamate and glycine and does not exhibit voltage dependence.	Glycine	80-87	nodal homolog 1 L homeolog	Xenopus laevis	14-18
9117561-5	1996	Splicing out of exon 15 results in the joining of exons 14 and 16, and formation of an Asp-Xaa-Ser-Gly consensus sequence for chondroitin sulfate chain attachment to serine 619 of L-APP, which lies 16 amino acids upstream of the A beta peptide sequence.	Glycine	99-102	amyloid beta precursor protein	Rattus norvegicus	229-235
8954779-6	1996	The predicted amino acid sequences of RBP56 protein have a serine-, tyrosine-, glutamine-, and glycine-rich region in the N-terminal region, an RNA binding domain and a C2C2 finger motif in the central region, and degenerate repeats of DR(S)GG(G)-YGG sequences in the C-terminal region.	Glycine	95-102	TATA-box binding protein associated factor 15	Homo sapiens	38-43
8916896-6	1996	In addition, computer models of the glycine loops from the wild-type and mutant enzymes were generated, using glycogen phosphorylase b as the structural template.	Glycine	36-43	glycogen phosphorylase B	Homo sapiens	110-134
8955518-17	1996	We therefore suggest that the glycine site plays a lesser role in modulating NMDA receptor function in the cerebellum and may explain why cells expressing NMDA receptors composed of NR1/NR2C subunits are particularly resistant to excitatory amino acid-induced neurotoxicity.	Glycine	30-37	glutamate ionotropic receptor NMDA type subunit 2C	Rattus norvegicus	186-190
8816444-0	1996	A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3.	Glycine	56-63	eukaryotic translation initiation factor 3 subunit A	Homo sapiens	158-162
8816444-6	1996	A region rich in aspartic acid, arginine, tyrosine, and glycine, termed the DRYG domain, is sufficient for self-association of eIF4B, both in vitro and in vivo, and for interaction with the p170 subunit of eIF3.	Glycine	56-63	eukaryotic translation initiation factor 3 subunit A	Homo sapiens	206-210
8810903-1	1996	Glycine N-methyltransferase (GNMT) from rat liver is a tetrameric enzyme with 292 amino acid residues in each identical subunit and catalyzes the S-adenosylmethionine (AdoMet) dependent methylation of glycine to form sarcosine.	Glycine	201-208	methionine adenosyltransferase 1A	Rattus norvegicus	168-174
8703082-5	1996	The mammalian Scip gene had alanine, glycine, proline, and histidine repeats, but the nonmammalian homologue completely lacked these repeats.	Glycine	37-44	POU class 3 homeobox 1	Homo sapiens	14-18
8884646-6	1996	Especially, DQB1*0503 and DQB1*0602 alleles carrying aspartic acid at position 57 and glycine at position 70 are increased significantly in EOP.	Glycine	86-93	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	12-16
8884646-6	1996	Especially, DQB1*0503 and DQB1*0602 alleles carrying aspartic acid at position 57 and glycine at position 70 are increased significantly in EOP.	Glycine	86-93	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	26-30
8794904-6	1996	Conversely, heteromeric NR1/NR2B receptors were more sensitive to activation by glycine than were NR1/NR2A receptors.	Glycine	80-87	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	28-32
8702933-1	1996	We previously showed that substitution of a glycine residue for the palmitoylated cysteine 341 of the human beta2-adrenergic receptor (Gly341beta2AR), increases the basal level of the receptor phosphorylation and reduces its ability to functionally interact with Gs.	Glycine	44-51	adrenoceptor beta 2	Homo sapiens	108-133
8718861-10	1996	Removal of the N-terminal region of the Trp-106--&gt;Gly variant by proteolytic cleavage substantially weakened the binding to papain and cathepsin B.	Glycine	53-56	cathepsin B	Homo sapiens	138-149
8757037-5	1996	Analysis of the COL1A1 gene that encodes the pro alpha 1(I) chains of type I procollagen revealed a point mutation in one allele, resulting in substitution of alanine for glycine (G13A) in about half the alpha 1(I) chains of type I collagen.	Glycine	171-178	collagen type I alpha 1 chain	Homo sapiens	16-22
8692979-7	1996	Alignment of the dGK and herpes simplex virus type 1 thymidine kinase amino acid sequences showed that five regions, including the substrate-binding pocket and the ATP-binding glycine loop, were also conserved in dGK.	Glycine	176-183	Diacyl glycerol kinase	Drosophila melanogaster	17-20
8692979-7	1996	Alignment of the dGK and herpes simplex virus type 1 thymidine kinase amino acid sequences showed that five regions, including the substrate-binding pocket and the ATP-binding glycine loop, were also conserved in dGK.	Glycine	176-183	Diacyl glycerol kinase	Drosophila melanogaster	213-216
8924628-1	1996	The peptide Boc-Gly-Dpg-Gly-Val-Ala-Leu-Aib-Val-Ala-Leu-OMe has been designed to examine the structural consequences of placing a short segment with a low helix propensity at the amino terminus of a helical heptapeptide module.	Glycine	24-27	ANIB1	Homo sapiens	40-43
8660675-11	1996	N-Fatty acylglycines are enzymatically produced in mammals from fatty acyl-coenzyme A (CoAs) and glycine by acyl-CoA:glycine N-acyltransferase.	Glycine	12-19	glycine-N-acyltransferase	Homo sapiens	108-142
8662907-9	1996	Mutational analysis revealed that glycine at position +1 of ST12 inhibited the binding to Grb2 while retaining the high affinity binding to CRK SH3.	Glycine	34-41	Kruppel like factor 6	Homo sapiens	60-64
8650173-5	1996	This activity is as much as 3 to 5 times stronger than VP16 at activating transcription and requires a large stretch of amino acids that contain glutamine-glycine rich and serine-threonine-basic amino acid rich regions.	Glycine	155-162	host cell factor C1	Homo sapiens	55-59
8752681-4	1996	These results disclosed a G-to-A transition within exon 73 of COL7A1, which results in a glycine-to-arginine substitution within the triple-helical domain of type VII collagen in affected individuals.	Glycine	89-96	collagen type VII alpha 1 chain	Homo sapiens	62-68
8605175-0	1996	The designed protein M(II)-Gly-Lys-His-Fos(138-211) specifically cleaves the AP-1 binding site containing DNA.	Glycine	27-30	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	39-42
8605175-1	1996	A new specific DNA cleavage protein, Gly-Lys-His-Fos(138-211), was designed, expressed, and characterized.	Glycine	37-40	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	49-52
8729973-5	1996	Two of 17 carcinomas showed Ki-ras mutations, both in codon 12 (gly --&gt; lys and gly --&gt; arg).	Glycine	64-67	KRAS proto-oncogene, GTPase	Homo sapiens	28-34
8729973-5	1996	Two of 17 carcinomas showed Ki-ras mutations, both in codon 12 (gly --&gt; lys and gly --&gt; arg).	Glycine	83-86	KRAS proto-oncogene, GTPase	Homo sapiens	28-34
8615045-7	1996	The results of our analyses show that two glycine residues (G10 and G13) located within the sequence FLGFLG in the middle of the fusion peptide are critical for syncytium formation and for the establishment of a productive infection, whereas other glycine residues (G3, G5, and G20) are more permissive to substitutions.	Glycine	42-49	BUD31 homolog	Homo sapiens	60-63
8615045-7	1996	The results of our analyses show that two glycine residues (G10 and G13) located within the sequence FLGFLG in the middle of the fusion peptide are critical for syncytium formation and for the establishment of a productive infection, whereas other glycine residues (G3, G5, and G20) are more permissive to substitutions.	Glycine	42-49	G protein subunit alpha 13	Homo sapiens	68-71
8615045-7	1996	The results of our analyses show that two glycine residues (G10 and G13) located within the sequence FLGFLG in the middle of the fusion peptide are critical for syncytium formation and for the establishment of a productive infection, whereas other glycine residues (G3, G5, and G20) are more permissive to substitutions.	Glycine	248-255	BUD31 homolog	Homo sapiens	60-63
8615045-7	1996	The results of our analyses show that two glycine residues (G10 and G13) located within the sequence FLGFLG in the middle of the fusion peptide are critical for syncytium formation and for the establishment of a productive infection, whereas other glycine residues (G3, G5, and G20) are more permissive to substitutions.	Glycine	248-255	G protein subunit alpha 13	Homo sapiens	68-71
8652624-3	1996	Synthetic peptides analogous to this region of MBP containing glycine and histidine are encephalitogenic if they lack the N-terminal half, residues 69-74.	Glycine	62-69	myelin basic protein	Rattus norvegicus	47-50
8704137-3	1996	WhGRP-1 contains two conserved domains, the RNA-binding motif (RNP motif) combined with a series of glycine-rich imperfect repeats, characteristic of a conserved family of plant RNA-binding proteins.	Glycine	100-107	glycine-rich RNA-binding protein blt801	Triticum aestivum	0-7
8599935-2	1996	Achondroplasia has recently been shown to result from a Gly to Arg substitution in the transmembrane domain of the fibroblast growth factor receptor 3 (FGFR3), although the molecular consequences of this mutation have not been investigated.	Glycine	56-59	fibroblast growth factor receptor 3	Homo sapiens	115-150
8599935-2	1996	Achondroplasia has recently been shown to result from a Gly to Arg substitution in the transmembrane domain of the fibroblast growth factor receptor 3 (FGFR3), although the molecular consequences of this mutation have not been investigated.	Glycine	56-59	fibroblast growth factor receptor 3	Homo sapiens	152-157
8664899-10	1996	In addition, two polymorphic mutations were identified in MPZ exon 5 and exon 6, which do not alter the codons for Gly(200) and Ser(228), respectively.	Glycine	115-118	myelin protein zero	Homo sapiens	58-61
8550313-13	1996	Cell adhesion to fibronectin and vitronectin was inhibited by peptides containing the Arg-Gly-Asp sequence.	Glycine	90-93	vitronectin	Homo sapiens	33-44
9739089-7	1998	In contrast to other known MAP kinase structures, the ATP-binding site of JNK3 is well ordered; the glycine-rich nucleotide-binding sequence forms a beta-strand-turn-beta-strand structure over the nucleotide.	Glycine	100-107	mitogen-activated protein kinase 10	Mus musculus	74-78
9703961-3	1998	PC1 also generated a peptide which after carboxypeptidase B treatment, was detected with an antiserum specific for CCK Gly.	Glycine	119-122	carboxypeptidase B1	Homo sapiens	41-59
9668111-0	1998	Some, but not all, glycine substitution mutations in COL7A1 result in intracellular accumulation of collagen VII, loss of anchoring fibrils, and skin blistering.	Glycine	19-26	collagen type VII alpha 1 chain	Homo sapiens	53-59
9680115-6	1998	One patient was found to have a codon 12 mutation with arginine substituting for glycine (GGT--&gt;CGT); the other was a codon 12 mutation with glutamine substituting for glycine (GGT--&gt;GAT).	Glycine	81-88	UDP glycosyltransferase 8	Homo sapiens	99-102
9755023-3	1998	The purpose of this study was: (1) to investigate the effect of the anticonvulsant agent, milacemide, a glycine pro-drug on STR-allodynia; (2) to compare this effect with that of milacemide on normal nociception (without STR); and (3) to determine the sensitivity of the anti-allodynic effect of milacemide to pretreatment with selective monoamine oxidase (MAO)-A (clorgyline) and MAO-B (L-deprenyl) inhibitors.	Glycine	104-111	monoamine oxidase B	Rattus norvegicus	381-386
7493955-2	1995	The monooxygenase, PAM, first catalyzes conversion of a glycine-extended pro-peptide to the corresponding alpha-hydroxyglycine derivative, and the lyase, PGL, then catalyzes breakdown of this alpha-hydroxyglycine derivative to the amidated peptide plus glyoxylate.	Glycine	56-63	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	19-22
33968740-1	2021	Background: The Glycine N-acyltransferase (GLYAT) gene encodes a protein that catalyzes the transfer of acyl groups from acyl CoA to glycine, resulting in acyl glycine and coenzyme A. Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast cancer (BC), has yet to be fully addressed.	Glycine	133-140	glycine-N-acyltransferase	Homo sapiens	16-41
7493955-2	1995	The monooxygenase, PAM, first catalyzes conversion of a glycine-extended pro-peptide to the corresponding alpha-hydroxyglycine derivative, and the lyase, PGL, then catalyzes breakdown of this alpha-hydroxyglycine derivative to the amidated peptide plus glyoxylate.	Glycine	56-63	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	154-157
9675061-3	1998	We have now improved the expression of TP2 over fivefold by (1) optimizing the codons for lysine, arginine, proline, leucine, glycine, valine, threonine, alanine, and tyrosine and (2) by engineering the vector-encoded 5" UTR.	Glycine	126-133	transition protein 2	Rattus norvegicus	39-42
9624170-5	1998	Significantly, we demonstrate that substitution of the nonpolar glycine residue for either or both of the conserved negatively charged aspartic acid residues at positions 174 and 175 in the full-length recombinant Nef protein background completely abrogated binding of c-Raf1 in vitro.	Glycine	64-71	TNF receptor associated factor 3	Homo sapiens	269-275
33968740-1	2021	Background: The Glycine N-acyltransferase (GLYAT) gene encodes a protein that catalyzes the transfer of acyl groups from acyl CoA to glycine, resulting in acyl glycine and coenzyme A. Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast cancer (BC), has yet to be fully addressed.	Glycine	133-140	glycine-N-acyltransferase	Homo sapiens	43-48
9579578-2	1998	It showed a 30 bp deletion at the carboxyl terminus with specific amino acid substitution Asp at codon 335 with reference to Gly in B95-8 LMP1.	Glycine	125-128	PDZ and LIM domain 7	Homo sapiens	138-142
8787788-1	1995	We have investigated the inhibitory effect of the N-terminal modified Arg-Gly-Asp-Ser (RGDS) analogues, AcDRGDS and AcDRLDS, on tumor cell adhesion to the components of extracellular matrix and basement membrane, and also tested the antimetastatic effect of their conjugates with trimesic acid, Ar(DRGDS)3 and Ar(DRLDS)3.	Glycine	74-77	ral guanine nucleotide dissociation stimulator	Mus musculus	87-91
33968740-1	2021	Background: The Glycine N-acyltransferase (GLYAT) gene encodes a protein that catalyzes the transfer of acyl groups from acyl CoA to glycine, resulting in acyl glycine and coenzyme A. Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast cancer (BC), has yet to be fully addressed.	Glycine	133-140	glycine-N-acyltransferase	Homo sapiens	193-198
33919285-4	2021	To this end, triglycine (HG3), a tripeptide of the amino acid glycine, was chosen as a chelating ligand for magnesium, given its natural occurrence and water solubility, and entropically-driven metal binding.	Glycine	16-23	polycystin 1, transient receptor potential channel interacting pseudogene 3	Homo sapiens	25-28
8746786-6	1995	Third, all IFN-tau, as well as the related IFN-omega, possess a Gly at position 126 (rather than the equivalent Arg on MuIFN-beta and IFN-alpha) that will impair an extensive hydrogen bonding interaction between helix D and loop AB.	Glycine	64-67	interferon-tau-like	Bos taurus	11-18
8552448-5	1995	Quantitative comparison of serine enrichment from these two tracers suggests that serine synthesis from glycine occurs via the combined action of the glycine cleavage enzyme system (GCE) and serine hydroxymethyltransferase (SHMT).	Glycine	104-111	serine hydroxymethyltransferase, cytosolic	Ovis aries	191-222
8552448-5	1995	Quantitative comparison of serine enrichment from these two tracers suggests that serine synthesis from glycine occurs via the combined action of the glycine cleavage enzyme system (GCE) and serine hydroxymethyltransferase (SHMT).	Glycine	104-111	serine hydroxymethyltransferase, cytosolic	Ovis aries	224-228
9593136-7	1998	After cloning of the gene, analysis of the complete nucleotide sequence (1,146 bp) showed that this ampC gene is close to blaCMY-2, from which it differs by three point mutations leading to amino acid substitutions Glu --&gt; Gly at position 22, Trp --&gt; Arg at position 201, and Ser --&gt; Asn at position 343.	Glycine	226-229	AmpC	Proteus mirabilis	122-130
9578462-6	1998	The NH2-terminal sequence of the 47,000- and 24,000-Mr species is Phe82-Ser-Ser-Phe-Pro-Gly, which is identical to that of stromelysin 2.	Glycine	88-91	matrix metallopeptidase 10	Homo sapiens	123-136
33863325-1	2021	BACKGROUND: Serine hydroxymethyltransferase 2 (SHMT2) is a vital metabolic enzyme in one carbon metabolism catalyzing the conversion of serine to glycine, which has been reported to play a crucial role in the progression of tumors.	Glycine	146-153	serine hydroxymethyltransferase 2	Homo sapiens	12-45
9747890-2	1998	Cytotoxic T lymphocytes specific for a Kb-restricted determinant from the herpes simplex virus glycoprotein B (gB) preferentially express a dominant TCRBV10 beta-chain with sequence conservation of a tryptophan-glycine located in the V-D junction.	Glycine	211-218	T cell receptor beta, variable 10	Mus musculus	149-156
7548083-7	1995	The experiments showed for MLT tetramer in aqueous phosphate buffer that the amino nitrogen of Gly-1 has a pKa of 8.15, and that the Lys-7, Lys-21, and Lys-23 side chain nitrogen atoms have pKa values of 10.21, 10.03, and 10.24 respectively.	Glycine	95-98	melittin	Apis mellifera	27-30
33863325-1	2021	BACKGROUND: Serine hydroxymethyltransferase 2 (SHMT2) is a vital metabolic enzyme in one carbon metabolism catalyzing the conversion of serine to glycine, which has been reported to play a crucial role in the progression of tumors.	Glycine	146-153	serine hydroxymethyltransferase 2	Homo sapiens	47-52
33936142-6	2021	The glycine mutations (eto1-11, eto1-12, and eto1-16) do not influence the mRNA abundance of ETO1, which is reflected by the mRNA secondary structure similar to that of WT.	Glycine	4-11	tetratricopeptide repeat (TPR)-containing protein	Arabidopsis thaliana	23-27
8991984-4	1995	These 2 alleles have glycine (Gly) or tyrosine (Tyr), and not hydrophobic leucine (Leu), at position 26 in the 2nd hypervariable region of the DQB1 first domain.	Glycine	21-28	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	143-147
8991984-4	1995	These 2 alleles have glycine (Gly) or tyrosine (Tyr), and not hydrophobic leucine (Leu), at position 26 in the 2nd hypervariable region of the DQB1 first domain.	Glycine	30-33	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	143-147
8991984-7	1995	CONCLUSION: The presence of Gly 26 or Tyr 26 in the HLA-DQB1 first domain in our cases with SSc and silicone implants is consistent with immunogenetic findings reported in Caucasian with idiopathic SSc anticentromere autoantibodies.	Glycine	28-31	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	52-60
9494104-7	1998	Expression of Mas-DH+Gly in strains deficient in either the Mkc7 or the Yap3 protease reduced proteolysis, while no proteolysis of Mas-DH+Gly was detectable in a strain lacking both proteases.	Glycine	21-24	aspartyl protease	Saccharomyces cerevisiae S288C	60-64
9605538-3	1998	Recent studies have shown that gephyrin colocalizes with GABA(A) receptors which, like those for glycine, are also inhibitory amino acid receptors usually associated with a chloride channel.	Glycine	97-104	gephyrin	Oryctolagus cuniculus	31-39
33936142-8	2021	Overall, these data suggest that the linker sequence between tetratricopeptide repeat (TPR) motifs and the glycine in TPR motifs or the linker region are essential for ETO1 to bind with downstream mediators, which strengthens our knowledge of ETO1 regulation in balancing ACSs.	Glycine	107-114	tetratricopeptide repeat (TPR)-containing protein	Arabidopsis thaliana	168-172
9498812-1	1998	The N-terminal glycine of transducin alpha subunits is acylated by lauroyl (C12:0), myristoyl (C14:0), (cis-delta5)-tetradecaenoyl (C14:1) or (cis,cis-delta5,delta8)-tetradecadienoyl (C14:2) fatty acyl groups.	Glycine	15-22	G protein subunit alpha z	Homo sapiens	26-42
33936142-8	2021	Overall, these data suggest that the linker sequence between tetratricopeptide repeat (TPR) motifs and the glycine in TPR motifs or the linker region are essential for ETO1 to bind with downstream mediators, which strengthens our knowledge of ETO1 regulation in balancing ACSs.	Glycine	107-114	tetratricopeptide repeat (TPR)-containing protein	Arabidopsis thaliana	243-247
33924373-5	2021	Perry disease-linked missense mutations (e.g., p.G71A) reside within the CAP-Gly domain and impair the microtubule-binding abilities of DCTN1.	Glycine	77-80	dynactin subunit 1	Homo sapiens	136-141
33918349-5	2021	Here, we identified a loss-of-function mutant of AtARP4 with a single nucleotide change from glycine to arginine, which had significantly smaller leaf size.	Glycine	93-100	actin-related protein 4	Arabidopsis thaliana	49-55
33515654-3	2021	Orexin-A potentiated the glycine currents by activating OX1R.	Glycine	25-32	hypocretin receptor 1	Homo sapiens	56-60
33515654-8	2021	In conclusion, after OX1R is activated, a distinct IP3/Ca2+-dependent PKC signaling pathway, is likely responsible for the orexin-A potentiation on glycine currents in the spinal cord ventral horn neurons.	Glycine	148-155	hypocretin receptor 1	Homo sapiens	21-25
33756123-7	2021	Inhibitors of the glycine transporters GlyT1 and GlyT2 lowered levels of PPIX and markers of oxidative stress selectively in K56211B4 cells, and in primary erythroid cultures from an EPP patient.	Glycine	18-25	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	49-54
33543617-4	2021	K1, K2, and GA might compete with d-glucose to form hydrogen bonds with the same active residues including GLU-412, GLY-416, GLN-314, and TRP-420 in GLUT2.	Glycine	116-119	solute carrier family 2 member 2	Homo sapiens	149-154
33217378-0	2021	Functional analysis of whether the glycine residue of the GMN motif of the Arabidopsis MRS2/MGT/CorA-type Mg2+ channel protein AtMRS2-11 is critical for Mg2+ transport activity.	Glycine	35-42	magnesium (Mg) transporter 10	Arabidopsis thaliana	127-136
33217378-8	2021	These results suggested that the Mg2+ transport activity of the AtMRS2-11 GMN-motif mutants was low at low physiological Mg2+ concentrations; thus, the Gly residue is critical for Mg2+ transport, and the Mg2+ transport activity of the GMN-motif mutants was increased at high Mg2+ concentrations.	Glycine	152-155	magnesium (Mg) transporter 10	Arabidopsis thaliana	64-73
33440850-5	2021	Cp deamidation occurs at two Asparagine-Glycine-Arginine (NGR)-motifs which, once deamidated to isoAspartate-Glycine-Arginine (isoDGR), bind integrins, a family of receptors mediating cell adhesion.	Glycine	40-47	reticulon 4 receptor	Homo sapiens	58-61
32770541-4	2021	COL1A1 and COL1A2 gene variants were identified in 44.23%, of which 28.84% were glycine substitution abnormalities.	Glycine	80-87	collagen type I alpha 1 chain	Homo sapiens	0-6
33718859-0	2021	A glycine substitution in the collagenous domain of Col4a3 in mice recapitulates late onset Alport syndrome.	Glycine	2-9	collagen, type IV, alpha 3	Mus musculus	52-58
33137310-8	2020	Our findings support the hypothesis that the TRAP-dependence is in part determined by the content of glycine and proline residues mainly within the signal sequence.	Glycine	101-108	TRAP	Homo sapiens	45-49
33273142-4	2020	This structure confirms the high structural flexibility of Gly-Aib peptides and points to a strong relationship between intermolecular hydrogen bonding and crystal quality and size.	Glycine	59-62	ANIB1	Homo sapiens	63-66
33177718-7	2020	Although in all JDPs the interaction of the characteristic J-domain is responsible for the activation of HSP70, in DNAJB1 the HSP70-binding sites in this domain are intrinsically blocked by an adjacent glycine-phenylalanine rich region-an inhibition that can be released upon the interaction of a second site on DNAJB1 with the HSP70 C-terminal tail.	Glycine	202-209	heat shock protein family A (Hsp70) member 4	Homo sapiens	105-110
33177718-7	2020	Although in all JDPs the interaction of the characteristic J-domain is responsible for the activation of HSP70, in DNAJB1 the HSP70-binding sites in this domain are intrinsically blocked by an adjacent glycine-phenylalanine rich region-an inhibition that can be released upon the interaction of a second site on DNAJB1 with the HSP70 C-terminal tail.	Glycine	202-209	heat shock protein family A (Hsp70) member 4	Homo sapiens	126-131
33177718-7	2020	Although in all JDPs the interaction of the characteristic J-domain is responsible for the activation of HSP70, in DNAJB1 the HSP70-binding sites in this domain are intrinsically blocked by an adjacent glycine-phenylalanine rich region-an inhibition that can be released upon the interaction of a second site on DNAJB1 with the HSP70 C-terminal tail.	Glycine	202-209	heat shock protein family A (Hsp70) member 4	Homo sapiens	126-131
33059700-7	2020	However, D-gal + Gly cotreatment reversed the neurotoxic effects of D-gal by downregulating p-JNK levels, which had been elevated by D-gal.	Glycine	17-20	mitogen-activated protein kinase 8	Mus musculus	94-97
33059700-8	2020	We also found that Gly reversed D-gal-induced neuroapoptosis by significantly reducing the protein expression levels of proapoptotic markers (Bax, cytochrome c, cleaved caspase-3, and cleaved PARP-1) and increasing the protein expression level of the antiapoptotic protein Bcl-2.	Glycine	19-22	BCL2-associated X protein	Mus musculus	142-145
33059700-8	2020	We also found that Gly reversed D-gal-induced neuroapoptosis by significantly reducing the protein expression levels of proapoptotic markers (Bax, cytochrome c, cleaved caspase-3, and cleaved PARP-1) and increasing the protein expression level of the antiapoptotic protein Bcl-2.	Glycine	19-22	caspase 3	Mus musculus	169-178
33059700-8	2020	We also found that Gly reversed D-gal-induced neuroapoptosis by significantly reducing the protein expression levels of proapoptotic markers (Bax, cytochrome c, cleaved caspase-3, and cleaved PARP-1) and increasing the protein expression level of the antiapoptotic protein Bcl-2.	Glycine	19-22	poly (ADP-ribose) polymerase family, member 1	Mus musculus	192-198
33059700-9	2020	Both the molecular docking approach and the in vitro study (in which the neuronal HT22 cells were treated with or without a p-JNK-specific inhibitor (SP600125)) further verified our in vivo findings that Gly bound to the p-JNK protein and inhibited its function and the JNK-mediated apoptotic pathway in the mouse brain and HT22 cells.	Glycine	204-207	mitogen-activated protein kinase 8	Mus musculus	126-129
33059700-9	2020	Both the molecular docking approach and the in vitro study (in which the neuronal HT22 cells were treated with or without a p-JNK-specific inhibitor (SP600125)) further verified our in vivo findings that Gly bound to the p-JNK protein and inhibited its function and the JNK-mediated apoptotic pathway in the mouse brain and HT22 cells.	Glycine	204-207	mitogen-activated protein kinase 8	Mus musculus	223-226
33059700-9	2020	Both the molecular docking approach and the in vitro study (in which the neuronal HT22 cells were treated with or without a p-JNK-specific inhibitor (SP600125)) further verified our in vivo findings that Gly bound to the p-JNK protein and inhibited its function and the JNK-mediated apoptotic pathway in the mouse brain and HT22 cells.	Glycine	204-207	mitogen-activated protein kinase 8	Mus musculus	223-226
33059700-11	2020	Finally, the addition of Gly reversed D-gal-induced synaptic dysfunction by upregulating the expression of memory-related presynaptic protein markers (synaptophysin (SYP), syntaxin (Syn), and a postsynaptic density protein (PSD95)) and markedly improved behavioral measures of cognitive deficits in D-gal-treated mice.	Glycine	25-28	discs large MAGUK scaffold protein 4	Mus musculus	224-229
33059700-12	2020	CONCLUSION: Our findings demonstrate that Gly-mediated deactivation of the JNK signaling pathway underlies the neuroprotective effect of Gly, which reverses D-gal-induced oxidative stress, apoptotic neurodegeneration, neuroinflammation, synaptic dysfunction, and memory impairment.	Glycine	42-45	mitogen-activated protein kinase 8	Mus musculus	75-78
9498393-9	1998	RESULTS: Systemic infusion of HGF increased galactose absorption 68% (P&lt;.05), glycine absorption 57% (P&lt;.05), DNA content 17% (P&lt;.01), and protein content 57% (P&lt;.01), when compared with the appropriate control.	Glycine	81-88	hepatocyte growth factor	Rattus norvegicus	30-33
33059700-12	2020	CONCLUSION: Our findings demonstrate that Gly-mediated deactivation of the JNK signaling pathway underlies the neuroprotective effect of Gly, which reverses D-gal-induced oxidative stress, apoptotic neurodegeneration, neuroinflammation, synaptic dysfunction, and memory impairment.	Glycine	137-140	mitogen-activated protein kinase 8	Mus musculus	75-78
9498393-10	1998	Luminal perfusion of HGF also increased galactose absorption 114% (P&lt;.01), glycine absorption 126% (P&lt;.01), DNA content 32% (P&lt;.01), and protein content 45% (P&lt;.01), when compared with the appropriate control.	Glycine	78-85	hepatocyte growth factor	Rattus norvegicus	21-24
32763315-3	2020	A construct which connects the cytoplasmic cofactor region of NS2B and NS3 protease with an artificial glycine-rich flexible linker has been widely used for structural, biochemical and drug-screening studies.	Glycine	103-110	KRAS proto-oncogene, GTPase	Homo sapiens	71-74
9502217-0	1998	Possible association of missense mutation (Gly[-63]Glu) of the neurotrophin-3 gene with Alzheimer"s disease in Japanese.	Glycine	43-46	neurotrophin 3	Homo sapiens	63-77
9502217-2	1998	We examined whether a missense mutation (Gly[-63]Glu) of the neurotrophin-3 (NT-3) gene is associated with Alzheimer"s disease (AD) in a Japanese sample of 123 patients and 215 controls.	Glycine	41-44	neurotrophin 3	Homo sapiens	61-75
9502217-2	1998	We examined whether a missense mutation (Gly[-63]Glu) of the neurotrophin-3 (NT-3) gene is associated with Alzheimer"s disease (AD) in a Japanese sample of 123 patients and 215 controls.	Glycine	41-44	neurotrophin 3	Homo sapiens	77-81
9490862-2	1998	The cross-modulation of glycine responses by cyclic-AMP-dependent protein kinase (PKA) and protein kinase C (PKC) was determined in acutely dissociated trigeminal neurons.	Glycine	24-31	protein kinase C, gamma	Rattus norvegicus	91-107
32763315-8	2020	The glycine-rich linker between NS2B and NS3 may promote the open conformation which interferes with protease activity.	Glycine	4-11	KRAS proto-oncogene, GTPase	Homo sapiens	41-44
9490862-2	1998	The cross-modulation of glycine responses by cyclic-AMP-dependent protein kinase (PKA) and protein kinase C (PKC) was determined in acutely dissociated trigeminal neurons.	Glycine	24-31	protein kinase C, gamma	Rattus norvegicus	109-112
32903271-1	2020	Serine hydroxymethyltransferase 2 (SHMT2) converts serine plus tetrahydrofolate (THF) into glycine plus methylene-THF and is upregulated at the protein level in lung and other cancers.	Glycine	91-98	serine hydroxymethyltransferase 2	Homo sapiens	0-33
32903271-1	2020	Serine hydroxymethyltransferase 2 (SHMT2) converts serine plus tetrahydrofolate (THF) into glycine plus methylene-THF and is upregulated at the protein level in lung and other cancers.	Glycine	91-98	serine hydroxymethyltransferase 2	Homo sapiens	35-40
32903271-4	2020	Knockdown of SHMT2 expression in vitro caused a state of glycine auxotrophy and accumulation of phosphoribosylaminoimidazolecarboxamide (AICAR), an intermediate of folate/1-carbon-pathway-dependent de novo purine nucleotide synthesis.	Glycine	57-64	serine hydroxymethyltransferase 2	Homo sapiens	13-18
9425086-15	1998	In addition, 14-3-3 zeta bound with lower affinity to a peptide based on the central region of the GP Ibalpha cytoplasmic domain (Arg-557-Gly-575), whereas peptide sequences within the cytoplasmic domains of GP Ibbeta (Arg-160-Arg-175) and GP V (Lys-529-Gly-544) bound 14-3-3 zeta with comparable affinity to the GHSL-containing peptide.	Glycine	138-141	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	Homo sapiens	13-24
9425086-15	1998	In addition, 14-3-3 zeta bound with lower affinity to a peptide based on the central region of the GP Ibalpha cytoplasmic domain (Arg-557-Gly-575), whereas peptide sequences within the cytoplasmic domains of GP Ibbeta (Arg-160-Arg-175) and GP V (Lys-529-Gly-544) bound 14-3-3 zeta with comparable affinity to the GHSL-containing peptide.	Glycine	138-141	glycoprotein Ib platelet subunit alpha	Homo sapiens	99-109
32883247-3	2020	Patients with Arginine:Glycine Amidino-Transferase deficiency (AGAT-d), due to the deficit of the first enzyme involved in Cr synthesis, are at a disadvantage due to their failure to synthesize Cr and their dependence on external intake, in contrast to normal subjects, where changes in Cr biosynthesis supply their needs.	Glycine	23-30	glycine amidinotransferase	Homo sapiens	63-67
10627137-0	1998	Four new cases of lethal osteogenesis imperfecta due to glycine substitutions in COL1A1 and genes.	Glycine	56-63	collagen type I alpha 1 chain	Homo sapiens	81-87
8550998-5	1995	At these time points, in both groups there was a specific two- to threefold increased net hepatic uptake of the amino acids alanine and glycine, both being transported by the sodium-coupled amino acid transport system A/ASC.	Glycine	136-143	PYD and CARD domain containing	Rattus norvegicus	220-223
32640336-7	2020	Also, GBH and Gly downregulated Hoxa10 and Lif genes, with no difference in Muc1 and Areg expression.	Glycine	14-17	LIF, interleukin 6 family cytokine	Rattus norvegicus	43-46
8541210-3	1995	These very large trx proteins differ only in a long Ser- and Gly-rich N-terminal extension, encoded by exon II, which is present only in the larger trx isoform.	Glycine	61-64	trithorax	Drosophila melanogaster	17-20
32330411-0	2020	Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.	Glycine	62-69	pyrroline-5-carboxylate reductase 2	Homo sapiens	8-13
8541210-3	1995	These very large trx proteins differ only in a long Ser- and Gly-rich N-terminal extension, encoded by exon II, which is present only in the larger trx isoform.	Glycine	61-64	trithorax	Drosophila melanogaster	148-151
7619799-5	1995	Kinetic analysis of the wild-type and mutant enzymes revealed that the amino acid differences occurring at positions 10 (Val/Ser), 11 (Arg/Pro), and 104 (Val/Gly) are responsible for the reduced enzymatic activity of Gst p-2.	Glycine	158-161	glutathione S-transferase, pi 2	Mus musculus	217-224
9440618-0	1997	Codon 201Arg/Gly polymorphism of DCC (deleted in colorectal carcinoma) gene in flat- and polypoid-type colorectal tumors.	Glycine	13-16	DCC netrin 1 receptor	Homo sapiens	33-36
9440618-0	1997	Codon 201Arg/Gly polymorphism of DCC (deleted in colorectal carcinoma) gene in flat- and polypoid-type colorectal tumors.	Glycine	13-16	DCC netrin 1 receptor	Homo sapiens	38-69
9440618-5	1997	DCC gene codon 201Arg/Gly polymorphism was investigated by polymerase chain reaction-based restriction fragment length polymorphism analysis, fluorescence-based dideoxy sequencing, or both.	Glycine	22-25	DCC netrin 1 receptor	Homo sapiens	0-3
32330411-0	2020	Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.	Glycine	62-69	serine hydroxymethyltransferase 2	Homo sapiens	81-86
32330411-5	2020	Mechanistically, we demonstrate that loss of PYCR2 upregulates SHMT2, which is responsible for glycine synthesis.	Glycine	95-102	pyrroline-5-carboxylate reductase 2	Homo sapiens	45-50
9412818-6	1997	Sequence analysis revealed a G-to-A transition at nucleotide 6127 in the triple-helical domain of COL7A1, which converted a glycine residue at amino acid position 2043 to an arginine.	Glycine	124-131	collagen type VII alpha 1 chain	Homo sapiens	98-104
9476130-3	1997	One point mutation in the codon for Gly at position 15 (GGT) of the B chain was found resulting in an amino acid substitution to Asp (GAT).	Glycine	36-39	glycine-N-acyltransferase	Homo sapiens	134-137
32330411-5	2020	Mechanistically, we demonstrate that loss of PYCR2 upregulates SHMT2, which is responsible for glycine synthesis.	Glycine	95-102	serine hydroxymethyltransferase 2	Homo sapiens	63-68
32330411-7	2020	Our findings identify the glycine metabolic pathway as a possible intervention point to alleviate the neurological symptoms of PYCR2-mutant patients.	Glycine	26-33	pyrroline-5-carboxylate reductase 2	Homo sapiens	127-132
32055850-5	2020	Glycine and 2HG concentrations as measured by MRS were correlated with tumor cell proliferation (MIB-1 labeling index), expression of mitochondrial serine hydroxymethyltransferase (SHMT2) and glycine decarboxylase (GLDC) enzymes, and patient overall survival.	Glycine	0-7	MIB E3 ubiquitin protein ligase 1	Homo sapiens	97-102
9548475-7	1997	Thus, the carboxyl-terminal five amino acids, Lys-Tyr-Glu-Gly-Lys (KYEGK), of the beta1 integrin cytoplasmic domain are critical for the coordinate tyrosine phosphorylation of three non-FAK substrates in human T cells.	Glycine	58-61	integrin subunit beta 1	Homo sapiens	82-96
32055850-5	2020	Glycine and 2HG concentrations as measured by MRS were correlated with tumor cell proliferation (MIB-1 labeling index), expression of mitochondrial serine hydroxymethyltransferase (SHMT2) and glycine decarboxylase (GLDC) enzymes, and patient overall survival.	Glycine	0-7	serine hydroxymethyltransferase 2	Homo sapiens	134-179
32055850-7	2020	Glycine concentration was positively correlated with MIB-1, and levels higher than 2.5 mM showed significant association with shorter patient survival, irrespective of IDH status.	Glycine	0-7	MIB E3 ubiquitin protein ligase 1	Homo sapiens	53-58
7777513-6	1995	The recombinant Mt-PK autophosphorylates a Ser residue and phosphorylates the synthetic peptide Gly-Arg-Gly-Leu-Ser-Leu-Ser-Arg, which contains a Ser residue in the phosphorylation site.	Glycine	96-99	DM1 protein kinase	Homo sapiens	16-21
32055850-10	2020	GLDC and SHMT2 expression were detectable in all tumors with glycine concentration, demonstrating an inverse correlation with GLDC.	Glycine	61-68	serine hydroxymethyltransferase 2	Homo sapiens	9-14
9396534-6	1997	RESULTS: The galactose absorption, glycine absorption, DNA content, and protein content were significantly increased by EGF (69%, 28%, 64%, and 55%, respectively) and gastrin (72%, 60%, 93%, and 48%, respectively) when compared with control.	Glycine	35-42	gastrin	Rattus norvegicus	167-174
32612281-6	2020	EA at PC6 resulted in downregulation of adenosine, adrenaline, gamma-aminobutyric acid, glycine, and glutamate majorly in hippocampus, and then in cerebral cortex.	Glycine	88-95	proprotein convertase subtilisin/kexin type 5	Rattus norvegicus	6-9
7669266-0	1995	Conformational modeling of elastin tetrapeptide Boc-Gly-Leu-Gly-Gly-NMe by molecular dynamics simulations with improvements to the thermalization procedure.	Glycine	52-55	elastin	Homo sapiens	27-34
32217768-6	2020	Here, we report that adjusting the number and positioning of fluorine atoms within the fluorophenyl ring of glycine derivatives produces isoform-selective KCNA1 channel openers that are inactive against KCNQ2/3 channels, or even KCNA2, the closest relative of KCNA1.	Glycine	108-115	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	203-210
9430431-10	1997	Phosphorylcholine esters and sulfhydryl reagents may prove useful in determining the contribution of phosphoserine phosphatase to the biosynthesis of glycine and D-serine in neuronal tissue in vitro.	Glycine	150-157	phosphoserine phosphatase	Homo sapiens	101-126
32477178-9	2020	Glycine concentration in the synaptic cleft is finely tuned by glycine transporters, i.e. GlyT1 and GlyT2, that regulate the neurotransmitter"s reuptake, with the first considered a highly potential target for psychosis therapy.	Glycine	0-7	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	100-105
9325342-7	1997	[125I]TBZ-AIPP derivatized a segment of rVMAT2 between Gly-408 and Cys-431 in TMD10 and 11.	Glycine	55-58	solute carrier family 18 member A2	Rattus norvegicus	40-46
7755581-6	1995	There was an 85% decrease in the cleavage of Arg-Gly-Arg-Phe-Arg-Arg-albumin compared with normal; also chicken proalbumin with an Arg-Phe-Ala-Arg processing site sequence was not a substrate for Kex2.	Glycine	49-52	kexin KEX2	Saccharomyces cerevisiae S288C	196-200
7774650-5	1995	Among mature thymocytes, P-gly activity is absent in the CD4+ subset but present in the more mature (HSAlow) fraction of CD8+ cells.	Glycine	27-30	CD4 antigen	Mus musculus	57-60
32347002-0	2020	Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.	Glycine	32-39	synaptic vesicle glycoprotein 2A	Homo sapiens	92-95
7730318-4	1995	First, the deduced polypeptide, which consists of 15 epidermal growth factor-like repeats, 3 TGF binding protein repeats, and 2 proline- and glycine-rich sequences, shows 38.4% identity with LTBP-1 but only 27% identity with fibrillin-1.	Glycine	141-148	latent transforming growth factor beta binding protein 1	Mus musculus	191-197
9352354-2	1997	Two polymorphisms occur in this pocket in the human class II MHC beta chain at position 85 and 86. beta 85 is usually Val, occasionally Ala, whereas beta 86 can be Gly or Val.	Glycine	164-167	major histocompatibility complex, class I, C	Homo sapiens	61-64
9311595-8	1997	These data demonstrate that peptide vaccination with a single mutant p21-ras-derived peptide induces CD4+ and CD8+ CTL specific for nested epitopes, including the Gly --&gt; Val substitution at codon 12, and that both these T-cell sub-sets specifically recognize tumour cells harbouring the corresponding K-ras mutation.	Glycine	163-166	CD8a molecule	Homo sapiens	110-113
9311595-8	1997	These data demonstrate that peptide vaccination with a single mutant p21-ras-derived peptide induces CD4+ and CD8+ CTL specific for nested epitopes, including the Gly --&gt; Val substitution at codon 12, and that both these T-cell sub-sets specifically recognize tumour cells harbouring the corresponding K-ras mutation.	Glycine	163-166	KRAS proto-oncogene, GTPase	Homo sapiens	305-310
9275097-3	1997	In contrast, using an antiserum specific for CCK Gly Arg Arg, Cpe(fat)/Cpe(fat) mice brain had about 13-fold higher levels of this peptide relative to controls, while levels were identical in mutant and control duodenal tissue.	Glycine	49-52	cholecystokinin	Mus musculus	45-48
9275097-3	1997	In contrast, using an antiserum specific for CCK Gly Arg Arg, Cpe(fat)/Cpe(fat) mice brain had about 13-fold higher levels of this peptide relative to controls, while levels were identical in mutant and control duodenal tissue.	Glycine	49-52	carboxypeptidase E	Mus musculus	62-65
9275097-3	1997	In contrast, using an antiserum specific for CCK Gly Arg Arg, Cpe(fat)/Cpe(fat) mice brain had about 13-fold higher levels of this peptide relative to controls, while levels were identical in mutant and control duodenal tissue.	Glycine	49-52	carboxypeptidase E	Mus musculus	71-74
32380971-11	2020	RESULTS: Among the target sequencing results of 527 patients, two novel mutations (Mut1: c.821A > G p.G274D, the adenine(A) was mutated to guanine(G) at position 821 of the SRF gene coding sequences (CDS), lead to the Glycine(G) mutated to Asparticacid(D) at position 274 of the SRF protein amino acid sequences; Mut2: c.880G > T p.G294C, the guanine(G) was mutated to thymine (T) at position 880 of the SRF CDS, lead to the Glycine(G) mutated to Cysteine (C) at position 294 of the SRF protein amino acid sequences.)	Glycine	218-225	serum response factor	Homo sapiens	173-176
9364921-1	1997	Previous mutational analysis of the L1 region of the RecA protein suggested that Gly-157 and Glu-158 are "hot-spots" for the occurrence of constitutive LexA co-protease mutants (coprt[c]).	Glycine	81-84	RAD51 recombinase	Homo sapiens	53-57
9218437-5	1997	The predominant amino acids detected by protein sequence analysis following cleavage of insoluble elastin with HME, MME, and 92-kDa gelatinase were Leu, Ile, Ala, Gly, and Val.	Glycine	163-166	elastin	Homo sapiens	98-105
7796152-7	1995	These results indicate that Acea 1021 and 7-chlorokynurenic acid can provide protection to CA1 neurons against ischemia-induced injury by a glycine-sensitive mechanism.	Glycine	140-147	carbonic anhydrase 1	Homo sapiens	91-94
9218437-8	1997	The amino acid residues detected in insoluble elastin following hydrolysis with porcine pancreatic elastase and human neutrophil elastase were predominantly Gly and Ala, with lesser amounts of Val, Phe, Ile, and Leu.	Glycine	157-160	elastin	Homo sapiens	46-53
32380971-11	2020	RESULTS: Among the target sequencing results of 527 patients, two novel mutations (Mut1: c.821A > G p.G274D, the adenine(A) was mutated to guanine(G) at position 821 of the SRF gene coding sequences (CDS), lead to the Glycine(G) mutated to Asparticacid(D) at position 274 of the SRF protein amino acid sequences; Mut2: c.880G > T p.G294C, the guanine(G) was mutated to thymine (T) at position 880 of the SRF CDS, lead to the Glycine(G) mutated to Cysteine (C) at position 294 of the SRF protein amino acid sequences.)	Glycine	218-225	serum response factor	Homo sapiens	279-282
32380971-11	2020	RESULTS: Among the target sequencing results of 527 patients, two novel mutations (Mut1: c.821A > G p.G274D, the adenine(A) was mutated to guanine(G) at position 821 of the SRF gene coding sequences (CDS), lead to the Glycine(G) mutated to Asparticacid(D) at position 274 of the SRF protein amino acid sequences; Mut2: c.880G > T p.G294C, the guanine(G) was mutated to thymine (T) at position 880 of the SRF CDS, lead to the Glycine(G) mutated to Cysteine (C) at position 294 of the SRF protein amino acid sequences.)	Glycine	218-225	serum response factor	Homo sapiens	279-282
9109651-9	1997	The glycine-rich loop between beta1 and beta2 helps to anchor the phosphates while the ribose ring is buried beneath beta-strand 2.	Glycine	4-11	hemoglobin, beta adult minor chain	Mus musculus	40-45
7823952-4	1995	Utilizing a series of truncated Msx-1 polypeptides, we show that multiple regions of Msx-1 contribute to repression, and these are rich in alanine, glycine, and proline residues.	Glycine	148-155	msh homeobox 1	Mus musculus	32-37
7823952-4	1995	Utilizing a series of truncated Msx-1 polypeptides, we show that multiple regions of Msx-1 contribute to repression, and these are rich in alanine, glycine, and proline residues.	Glycine	148-155	msh homeobox 1	Mus musculus	85-90
32380971-11	2020	RESULTS: Among the target sequencing results of 527 patients, two novel mutations (Mut1: c.821A > G p.G274D, the adenine(A) was mutated to guanine(G) at position 821 of the SRF gene coding sequences (CDS), lead to the Glycine(G) mutated to Asparticacid(D) at position 274 of the SRF protein amino acid sequences; Mut2: c.880G > T p.G294C, the guanine(G) was mutated to thymine (T) at position 880 of the SRF CDS, lead to the Glycine(G) mutated to Cysteine (C) at position 294 of the SRF protein amino acid sequences.)	Glycine	425-432	serum response factor	Homo sapiens	173-176
32380971-11	2020	RESULTS: Among the target sequencing results of 527 patients, two novel mutations (Mut1: c.821A > G p.G274D, the adenine(A) was mutated to guanine(G) at position 821 of the SRF gene coding sequences (CDS), lead to the Glycine(G) mutated to Asparticacid(D) at position 274 of the SRF protein amino acid sequences; Mut2: c.880G > T p.G294C, the guanine(G) was mutated to thymine (T) at position 880 of the SRF CDS, lead to the Glycine(G) mutated to Cysteine (C) at position 294 of the SRF protein amino acid sequences.)	Glycine	425-432	serum response factor	Homo sapiens	279-282
32380971-11	2020	RESULTS: Among the target sequencing results of 527 patients, two novel mutations (Mut1: c.821A > G p.G274D, the adenine(A) was mutated to guanine(G) at position 821 of the SRF gene coding sequences (CDS), lead to the Glycine(G) mutated to Asparticacid(D) at position 274 of the SRF protein amino acid sequences; Mut2: c.880G > T p.G294C, the guanine(G) was mutated to thymine (T) at position 880 of the SRF CDS, lead to the Glycine(G) mutated to Cysteine (C) at position 294 of the SRF protein amino acid sequences.)	Glycine	425-432	serum response factor	Homo sapiens	279-282
9097020-2	1997	mSAP49 contains two RNA recognition motifs (RRM) in the N terminus of the predicted amino acid sequence, and a highly basic C terminus rich in glycine/proline.	Glycine	143-150	splicing factor 3b, subunit 4	Mus musculus	0-6
7756615-6	1995	The time-dependent increase in glycine responses was reduced by either tamoxifen, an inhibitor of PKC, or by alkaline phosphatase.	Glycine	31-38	protein kinase C, gamma	Rattus norvegicus	98-101
31794058-8	2020	Eight COL1A1/COL1A2 variants were novel and five recurrent with a predominance of glycine substitutions affecting residues within the procollagen N-proteinase cleavage site of alpha1(I) and alpha2(I) procollagens.	Glycine	82-89	collagen type I alpha 1 chain	Homo sapiens	6-12
9079657-3	1997	Factor Xa or catalytically inactive 5-dimethylaminonaphthalene-1sulfonyl (dansyl) Glu-Gly-Arg-(DEGR)-chloromethylketone-factor Xa bound indistinguishably to HUVEC and EPR-1 transfectants, and inhibited equally well the binding of 125I-factor Xa to these cells.	Glycine	86-89	coagulation factor X	Homo sapiens	0-9
9079657-3	1997	Factor Xa or catalytically inactive 5-dimethylaminonaphthalene-1sulfonyl (dansyl) Glu-Gly-Arg-(DEGR)-chloromethylketone-factor Xa bound indistinguishably to HUVEC and EPR-1 transfectants, and inhibited equally well the binding of 125I-factor Xa to these cells.	Glycine	86-89	coagulation factor X	Homo sapiens	120-129
31376158-8	2020	Although NMDAR-dependent, NYX-2925-mediated colocalization of GluN2B with PSD-95 occurred independent of ion flux, as colocalization increased in the presence of either the NMDAR channel blocker (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate or glycine site antagonist 7-chlorokynurenic acid.	Glycine	289-296	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	62-68
9079657-3	1997	Factor Xa or catalytically inactive 5-dimethylaminonaphthalene-1sulfonyl (dansyl) Glu-Gly-Arg-(DEGR)-chloromethylketone-factor Xa bound indistinguishably to HUVEC and EPR-1 transfectants, and inhibited equally well the binding of 125I-factor Xa to these cells.	Glycine	86-89	coagulation factor X	Homo sapiens	235-244
9079657-5	1997	A factor X peptide duplicating the inter-EGF sequence Leu83-Phe84-Thr85-Arg86-Lys87-Leu88- (Gly) inhibited factor V/Va-independent prothrombin activation by HUVEC and blocked binding of 125I-factor Xa to these cells in a dose-dependent manner (IC50 approximately 20-40 microM).	Glycine	92-95	coagulation factor X	Homo sapiens	191-200
8608088-1	1995	The tetrapeptide, Arg-Gly-Asp-Ser (RGDS), which corresponds to a core sequence of cell adhesion proteins, was coimmobilized with insulin on to surface-hydrolyzed poly(methyl methacrylate) film.	Glycine	22-25	ral guanine nucleotide dissociation stimulator	Mus musculus	35-39
31672571-2	2020	In the current study, we show that crd1Delta cells exhibit decreased levels of glutamate and cysteine and are deficient in the essential antioxidant, glutathione, a tripeptide of glutamate, cysteine, and glycine.	Glycine	204-211	cardiolipin synthase	Saccharomyces cerevisiae S288C	35-39
9136983-3	1997	A remarkably conserved mutation (Gly 380--&gt;Arg) in the transmembrane region of FGFR-3 has been shown to be responsible for achondroplasia (ACH) but it was not clear whether such mutations result in loss of receptor function or constitutive activation.	Glycine	33-36	fibroblast growth factor receptor 3	Homo sapiens	82-88
9148753-5	1997	The N-terminal sequence of the two fragments generated by MMP-2 and MMP-3 is Leu211-Lys-Gly-Leu-Asn, but that of the others is Asp1-Glu-Ala-Ser-Gly.	Glycine	144-147	beta-secretase 2	Homo sapiens	127-131
7527388-4	1994	P38 can be phosphorylated in vitro by a src-related protein tyrosine kinase on multiple tyrosine residues located predominantly in the glycine-rich domain.	Glycine	135-142	p38b MAP kinase	Drosophila melanogaster	0-3
31877957-9	2019	ASCT2 gene expression was significantly upregulated after 120 muM Cu-Glycine and CuSO4 exposure, and PepT1 gene expression was significantly upregulated after Cu-Pro exposure.	Glycine	69-76	solute carrier family 1 member 5	Sus scrofa	0-5
7527388-7	1994	The latter phosphorylation site is located in the glycine-rich domain of P38.	Glycine	50-57	p38b MAP kinase	Drosophila melanogaster	73-76
9032446-3	1997	In contrast, Lys-174 is conserved except in a yeast isoenzyme, fbp26, where it is replaced by glycine.	Glycine	94-101	fructose-2,6-bisphosphatase	Saccharomyces cerevisiae S288C	63-68
31659941-6	2019	Furthermore, glycine receptor-immunoreactivity was observed in these TRH neurons.	Glycine	13-20	thyrotropin releasing hormone	Mus musculus	69-72
9008239-12	1997	These cases illustrate the consequences of COL7A1 glycine substitution mutations underlying DEB in terms of the mode of inheritance and the phenotype, with profound implications for genetic counseling of individuals at risk for recurrence of DEB in subsequent offspring or future generations.	Glycine	50-57	collagen type VII alpha 1 chain	Homo sapiens	43-49
7963683-3	1994	In this overview, we summarize our recent discoveries of pathogenic mutations in COL7A1, including premature termination codons that result in the severe, mutilating (Hallopeau-Siemens) type of recessive dystrophic EB and a glycine substitution in the collagenous region resulting in dominant dystrophic EB.	Glycine	224-231	collagen type VII alpha 1 chain	Homo sapiens	81-87
7945373-2	1994	Its nucleotide sequence predicts a preprocorazonin consisting of an 19 amino acid putative signal peptide, the 11 amino acid corazonin sequence, a Gly used for amidation, a Lys-Arg proteolytic processing site, and a 39 amino acid corazonin-precursor-related peptide (CPRP).	Glycine	147-150	Corazonin	Drosophila melanogaster	41-50
31659941-8	2019	Patch-clamp electrophysiology using sections of TRH-IRES-tdTomato mice showed that glycine hyperpolarized the TRH neurons and completely blocked the firing of these neurons.	Glycine	83-90	thyrotropin releasing hormone	Mus musculus	48-51
9037498-1	1997	As N-methyl-D-aspartate receptor (NMDA) ionophore complexes have a distinct positive, allosteric regulatory site for glycine, it has been proposed that elevated extracellular glycine during or after cerebral ischaemia may induce excessive NMDA/glutamate receptor activation and, thereby, excitotoxicity.	Glycine	175-182	glutamate ionotropic receptor NMDA type subunit 2C	Rattus norvegicus	239-262
31659941-8	2019	Patch-clamp electrophysiology using sections of TRH-IRES-tdTomato mice showed that glycine hyperpolarized the TRH neurons and completely blocked the firing of these neurons.	Glycine	83-90	thyrotropin releasing hormone	Mus musculus	110-113
9037498-8	1997	Nevertheless, as occupation of the glycine site coupled to the NMDA-receptor is required for NMDA/glutamate receptor activation, this site remains an attractive target for potential neuroprotective agents.	Glycine	35-42	glutamate ionotropic receptor NMDA type subunit 2C	Rattus norvegicus	93-116
31659941-9	2019	Glycine also markedly hyperpolarized the TRH neurons in the presence of tetrodotoxin demonstrating the direct effect of glycine.	Glycine	0-7	thyrotropin releasing hormone	Mus musculus	41-44
31659941-9	2019	Glycine also markedly hyperpolarized the TRH neurons in the presence of tetrodotoxin demonstrating the direct effect of glycine.	Glycine	120-127	thyrotropin releasing hormone	Mus musculus	41-44
7841367-1	1994	We have previously shown that a metabolically stable analogue of MPF, the C-terminal tetrapeptide of human beta-endorphin of structure Lys-Lys-Gly-Glu, reduces the turning behaviour of rats with unilateral lesions of their nigro-striatal pathways.	Glycine	143-146	mesothelin	Homo sapiens	65-68
31659941-11	2019	The glycine antagonist, strychnine, almost completely abolished these sIPSCs, demonstrating the inhibitory nature of the glycinergic input of TRH neurons.	Glycine	4-11	thyrotropin releasing hormone	Mus musculus	142-145
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	142-149	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	66-71
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	142-149	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	96-101
31701029-6	2019	Combining KCNQ2- and KCNQ3-specific glycine derivatives synergistically potentiated KCNQ2/3 activation by exploiting heteromeric channel composition.	Glycine	36-43	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	84-91
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	142-149	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	96-101
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	142-149	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	96-101
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	188-195	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	66-71
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	188-195	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	96-101
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	188-195	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	96-101
8999870-8	1997	However, transfection of Chinese hamster ovary cells deficient in mSHMT activity with the human mSHMT gene lacking exon 1 overcame the cell"s glycine auxotrophy and restored intracellular glycine concentrations to that observed in wild-type cells, showing that exon 1 is not essential for mSHMT localization or activity and that translation initiation from the second ATG is sufficient for mSHMT import into the mitochondria.	Glycine	188-195	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	96-101
9324163-5	1997	Glycine-extended gastrin had no effect at 100 nM and a small but significant effect at 1 microM.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
7803850-5	1994	Sequence analysis of the col-1 gene in the three temperature-sensitive mutants revealed that each allele of sqt-3 has a unique missense mutation causing arginine or glutamic acid to replace glycine in a Gly-X-Y triple helical domain.	Glycine	190-197	Cuticle collagen 1	Caenorhabditis elegans	108-113
7803850-5	1994	Sequence analysis of the col-1 gene in the three temperature-sensitive mutants revealed that each allele of sqt-3 has a unique missense mutation causing arginine or glutamic acid to replace glycine in a Gly-X-Y triple helical domain.	Glycine	203-206	Cuticle collagen 1	Caenorhabditis elegans	108-113
7521375-4	1994	Two clones of the sheep KAP5 gene family were isolated: the KAP5.4 cDNA encodes a protein of 190 amino acids (M(r) = 16,936) containing 32 mol% cysteine, 26 mol% glycine and the partial KAP5.5 cDNA encodes a protein of at least 197 amino acids (M(r) &gt; or = 17,474) containing 29 mol% cysteine, 28 mol% glycine.	Glycine	162-169	KAP5.4 keratin protein	Ovis aries	60-66
31773687-2	2019	Mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in the synthesis of serine and glycine, which has prognostic and therapeutic value for many malignant tumors.	Glycine	103-110	serine hydroxymethyltransferase 2	Homo sapiens	14-47
9120775-9	1997	These studies suggest that the glycoprotein IIb/IIIa complex, present on activated-platelets, may interact with fibronectin and vitronectin substrates through the Arg-Gly-Asp-dependent mechanism.	Glycine	167-170	vitronectin	Homo sapiens	128-139
31363794-3	2019	Glycine substitutions in COL1A1 resulted in the severe phenotype.	Glycine	0-7	collagen type I alpha 1 chain	Homo sapiens	25-31
9211270-0	1997	Lipoate addition to acyltransferases of alpha-keto acid dehydrogenase complexes and H-protein of glycine cleavage system.	Glycine	97-104	myosin binding protein H	Homo sapiens	84-93
7521375-4	1994	Two clones of the sheep KAP5 gene family were isolated: the KAP5.4 cDNA encodes a protein of 190 amino acids (M(r) = 16,936) containing 32 mol% cysteine, 26 mol% glycine and the partial KAP5.5 cDNA encodes a protein of at least 197 amino acids (M(r) &gt; or = 17,474) containing 29 mol% cysteine, 28 mol% glycine.	Glycine	305-312	KAP5.4 keratin protein	Ovis aries	60-66
31363794-14	2019	Patients with glycine substitution on COL1A1 had a higher frequency of fractures and were more severely short-statured.	Glycine	14-21	collagen type I alpha 1 chain	Homo sapiens	38-44
7915137-9	1994	Arg16--&gt;Gly+Gln27--&gt;Glu also underwent an increased downregulation compared to wild-type beta 2AR (39 +/- 4%).	Glycine	11-14	adrenoceptor beta 2	Homo sapiens	95-103
31363794-18	2019	This study revealed that glycine substitutions on COL1A1 resulted in the severe phenotype among Japanese patients with OI.	Glycine	25-32	collagen type I alpha 1 chain	Homo sapiens	50-56
8955162-1	1996	Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) is an essential 455-residue, monomeric enzyme that catalyzes the transfer of myristate from myristoyl-CoA to the NH2-terminal Gly residue of cellular proteins.	Glycine	204-207	glycylpeptide N-tetradecanoyltransferase NMT1	Saccharomyces cerevisiae S288C	71-76
31278967-9	2019	Pro, Gly and Ala were preferably found at P1-P4 and P2"-P4" in both tropoelastin and elastin.	Glycine	5-8	elastin	Homo sapiens	68-80
8931541-2	1996	These duplexes constitute the sequence 29-39 of the K-ras gene coding for the glycine 12, a hot spot for mutation.	Glycine	78-85	KRAS proto-oncogene, GTPase	Homo sapiens	52-57
7913883-8	1994	Both mutations result in the substitution of an arginine residue for a glycine at position 380 of the mature protein, which is in the transmembrane domain of FGFR3.	Glycine	71-78	fibroblast growth factor receptor 3	Homo sapiens	158-163
8027063-2	1994	Nmt1p transfers myristate (C14:0), from myristoyl-CoA to the amino-terminal Gly residue of several essential cellular proteins.	Glycine	76-79	glycylpeptide N-tetradecanoyltransferase NMT1	Saccharomyces cerevisiae S288C	0-5
31278967-9	2019	Pro, Gly and Ala were preferably found at P1-P4 and P2"-P4" in both tropoelastin and elastin.	Glycine	5-8	elastin	Homo sapiens	73-80
31271215-13	2019	Besides, Cirbp-/- resulted in decreased levels of creatine kinase B, glycine amidinotransferase, adenosine triphosphate and creatine contents in the intestine, affecting energy metabolism and balance, which is associated with the maintenance of epithelial barrier during acute injury.	Glycine	69-76	cold inducible RNA binding protein	Rattus norvegicus	9-14
8002963-4	1994	The proline-rich peptide shows high sequence similarities with drosocin, an O-glycosylated antibacterial peptide from Drosophila, and also with the N-terminal domain of diptericin, an inducible 9 kDa antibacterial peptide from members of the order Diptera, whereas the glycine-rich peptide has similarities with the glycine-rich domain of diptericin.	Glycine	269-276	Diptericin A	Drosophila melanogaster	169-179
8002963-4	1994	The proline-rich peptide shows high sequence similarities with drosocin, an O-glycosylated antibacterial peptide from Drosophila, and also with the N-terminal domain of diptericin, an inducible 9 kDa antibacterial peptide from members of the order Diptera, whereas the glycine-rich peptide has similarities with the glycine-rich domain of diptericin.	Glycine	316-323	Diptericin A	Drosophila melanogaster	169-179
8918261-3	1996	These vectors allow the production in high yield of either native proteins or of fusion proteins which contain, at their amino terminus, the peptide Met Gly His6 Ser Gly Leu Phe Lys Arg/, where Leu Phe Lys Arg/ is the recognition site for Kex2 protease which cleaves at the site indicated by /.	Glycine	153-156	kexin KEX2	Saccharomyces cerevisiae S288C	239-243
8918261-3	1996	These vectors allow the production in high yield of either native proteins or of fusion proteins which contain, at their amino terminus, the peptide Met Gly His6 Ser Gly Leu Phe Lys Arg/, where Leu Phe Lys Arg/ is the recognition site for Kex2 protease which cleaves at the site indicated by /.	Glycine	166-169	kexin KEX2	Saccharomyces cerevisiae S288C	239-243
31254495-6	2019	hPHT2 showed relatively low affinity for Gly-Sar and relatively high affinity for d3-L-histidine, with Km values of 428 +- 88 muM and 66.9 +- 5.7 muM, respectively.	Glycine	41-44	solute carrier family 15 member 3	Homo sapiens	0-5
8855938-1	1996	The crystal structure of the noncovalent complex of bovine thrombin and a fibrinogen-A alpha tridecapeptide substrate analog, G17 psi, in which the scissile bond amide nitrogen of Gly-17f has been replaced by a methylene carbon, has been determined at 2.3 A resolution with an R factor of 17.1%.	Glycine	180-183	coagulation factor II, thrombin	Bos taurus	59-67
8873759-9	1996	To test the importance of MARCKS myristoylation to its developmental role, an otherwise identical transgene was constructed in which the glycine at the amino terminus of MARCKS was mutated to an alanine.	Glycine	137-144	myristoylated alanine rich protein kinase C substrate	Mus musculus	170-176
7525451-3	1994	Two amino acid polymorphisms were identified for ICAM-1; Gly or Arg at codon 241 and Lys or Glu at codon 469.	Glycine	57-60	intercellular adhesion molecule 1	Homo sapiens	49-55
31199181-2	2019	We investigated the structure and function of the Asn-Gly deamidation in a human anti-CD52 IgG1 antibody light chain complementarity-determining region 1, and risk mitigation through protein engineering.	Glycine	54-57	CD52 molecule	Homo sapiens	86-90
7950368-4	1994	The purified dUTPase has two additional vector-encoded residues at the amino terminus (gly-ser), but they have no apparent effect on the activity of the enzyme since the recombinant dUTPase has catalytic properties similar to those reported for dUTPase purified from human cells (32.3 U/mg, kcat = 25 s-1, Km = 2.6 microM).	Glycine	87-90	Deoxyuridine triphosphatase	Drosophila melanogaster	13-20
8792713-4	1996	Retrospectively, a K-ras point mutation at codon 12 from GGT (glycine) to GAT (aspartic acid) was detected in the PPJ collected endoscopically 3 yr and 6 months earlier, as well as in the PPJ when PC was diagnosed and in the resected tumor tissue.	Glycine	62-69	KRAS proto-oncogene, GTPase	Homo sapiens	19-24
8816895-14	1996	Only one MS case (8%) showed K-ras mutation (codon 13 GGC &gt; GAC; glycine &gt; aspartate), which is in contrast to 2 of the TS cases (15%), showing codon 12 mutations.	Glycine	68-75	KRAS proto-oncogene, GTPase	Homo sapiens	29-34
31289137-2	2019	Mitochondrial C1 metabolism, including serine hydroxymethyltransferase (SHMT) 2, provides glycine, NAD(P)H, ATP, and C1 units for cytosolic biosynthetic reactions, and is implicated in the oncogenic phenotype across a wide range of cancers.	Glycine	90-97	serine hydroxymethyltransferase 2	Homo sapiens	39-79
8794860-5	1996	Mlp84B encodes a protein with five tandem LIM-glycine modules.	Glycine	46-53	LIM homeobox 1	Drosophila melanogaster	42-45
8012773-5	1994	The most frequent mutation (8/9) was a G to T transversion converting GGC to GTC, which would result in a glycine to valine substitution.	Glycine	106-113	gamma-glutamylcyclotransferase	Homo sapiens	70-73
8012773-6	1994	The remaining mutations was a G to A transition altering GGC to GAC, producing a glycine to aspartic acid substitution, which has not previously been reported in bladder cancer.	Glycine	81-88	gamma-glutamylcyclotransferase	Homo sapiens	57-60
8904769-0	1996	The Gly/Glu polymorphism of the neurotrophin 3 gene: allele frequencies in a Caucasian population and relevance for psychiatric disorders.	Glycine	4-7	neurotrophin 3	Homo sapiens	32-46
31442042-1	2019	Mitochondrial serine hydroxymethyl transferase isoform 2 (SHMT2) has attracted increasing attention as a pivotal catalyzing regulator of the serine/glycine pathway in the one-carbon metabolism of cancer cells.	Glycine	148-155	serine hydroxymethyltransferase 2	Homo sapiens	14-56
8904769-1	1996	Using a modified method for the determination of the genotype of the neurotrophin 3 Gly/Glu polymorphism by PCR, we investigated allele frequencies in patients suffering from different psychiatric diseases as well as in healthy controls.	Glycine	84-87	neurotrophin 3	Homo sapiens	69-83
8652535-4	1996	In order to assess the structural and functional role of the helical domain, we engineered a variant of I-FABP by deleting residues 15-31 and inserting a Ser-Gly linker after residue 14.	Glycine	158-161	fatty acid binding protein 2	Rattus norvegicus	104-110
8088784-7	1994	All exons in the COL7A1 triple helix coding region that do not begin with sequences corresponding to imperfections of the triple helix begin with intact codons for Gly residues of Gly-X-Y repeats.	Glycine	164-167	collagen type VII alpha 1 chain	Homo sapiens	17-23
8088784-7	1994	All exons in the COL7A1 triple helix coding region that do not begin with sequences corresponding to imperfections of the triple helix begin with intact codons for Gly residues of Gly-X-Y repeats.	Glycine	180-183	collagen type VII alpha 1 chain	Homo sapiens	17-23
8175672-1	1994	The metalloendopeptidase EC 3.4.24.15 is believed to degrade gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) by cleavage at the Tyr5-Gly6 bond.	Glycine	121-124	thimet oligopeptidase 1	Rattus norvegicus	4-24
8175672-1	1994	The metalloendopeptidase EC 3.4.24.15 is believed to degrade gonadotropin-releasing hormone (GnRH) (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) by cleavage at the Tyr5-Gly6 bond.	Glycine	137-140	thimet oligopeptidase 1	Rattus norvegicus	4-24
31442042-1	2019	Mitochondrial serine hydroxymethyl transferase isoform 2 (SHMT2) has attracted increasing attention as a pivotal catalyzing regulator of the serine/glycine pathway in the one-carbon metabolism of cancer cells.	Glycine	148-155	serine hydroxymethyltransferase 2	Homo sapiens	58-63
31273098-4	2019	N-terminal glycine degrons are depleted at native N-termini but strongly enriched at caspase cleavage sites, suggesting roles for the substrate adaptors ZYG11B and ZER1 in protein degradation during apoptosis.	Glycine	11-18	zyg-11 family member B, cell cycle regulator	Homo sapiens	153-159
8163493-10	1994	These results suggest that ligand-mediated internalization of the human IGF-I is consistent with saturable interactions between the IGF-I receptor juxtamembrane region (glycine 940-tyrosine 957) and components of the endocytic apparatus.	Glycine	169-176	insulin like growth factor 1 receptor	Homo sapiens	132-146
8725274-4	1996	Of the serine produced, 50.4 +/- 4.3% was derived from glycine via the action of serine hydroxymethyltransferase (SHMT) and the glycine cleavage enzyme complex (GCS).	Glycine	55-62	serine hydroxymethyltransferase, cytosolic	Ovis aries	81-112
8725274-4	1996	Of the serine produced, 50.4 +/- 4.3% was derived from glycine via the action of serine hydroxymethyltransferase (SHMT) and the glycine cleavage enzyme complex (GCS).	Glycine	55-62	serine hydroxymethyltransferase, cytosolic	Ovis aries	114-118
7513610-6	1994	In cell adhesion assays, the 69-6-5 mAb was able to inhibit strongly in a dose-dependent manner arginine-glycine-aspartic acid-mediated adhesion of HT29-D4 cells to vitronectin, fibronectin, or ProNectin F but not to laminin or collagen.	Glycine	105-112	vitronectin	Homo sapiens	165-176
8003047-2	1994	On the other hand, condensation of 2-dodecyltetradecanyl esters of glycine and 6-aminohexanoic acid with Boc-L-Ala-D-Glu-NH2 gave the corresponding lipophilic tripeptides, which upon coupling with alpha-benzyl-4,6-O-benzylyden-N-acetylmuramic acid yielded lipophilic esters of muramoyltripeptides.	Glycine	67-74	BOC cell adhesion associated, oncogene regulated	Homo sapiens	105-108
8618021-4	1996	These results disclosed a G-to-A transition within exon 73 of COL7A1, which results in a glycine-to-arginine substitution within the triple-helical domain of type VII collagen in affected individuals.	Glycine	89-96	collagen type VII alpha 1 chain	Homo sapiens	62-68
31273098-5	2019	Furthermore, ZYG11B and ZER1 were found to participate in the quality control of N-myristoylated proteins, in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation.	Glycine	127-134	zyg-11 family member B, cell cycle regulator	Homo sapiens	13-19
30964837-0	2019	SHMT2 Promotes Liver Regeneration Through Glycine-activated Akt/mTOR Pathway.	Glycine	42-49	serine hydroxymethyltransferase 2	Homo sapiens	0-5
8601595-2	1996	In the present work we examine the role of N-linked glycosylation and Ser-Gly motifs in regulating CD44-hyaluronate interaction.	Glycine	74-77	CD44 molecule (Indian blood group)	Homo sapiens	99-103
30964837-3	2019	Serine hydroxymethyl-transferase 2 (SHMT2) serves as the key enzyme in the biosynthesis of glycine.	Glycine	91-98	serine hydroxymethyltransferase 2	Homo sapiens	0-34
30914323-8	2019	In addition to the conserved RNA recognition motif (RRM), arginine-rich/serine-rich regions (RS domains) and a linker region, a glycine-rich region located between the RRM and RS2 was observed in Tra2-alpha and Tra2-gamma of Ae.	Glycine	128-135	transformer 2	Drosophila melanogaster	196-200
8631028-0	1996	Gastrimmune raises antibodies that neutralize amidated and glycine-extended gastrin-17 and inhibit the growth of colon cancer.	Glycine	59-66	gastrin	Rattus norvegicus	76-83
8135811-8	1994	The Gly-214 (GGC) residue was therefore conserved in the enzymes hitherto isolated from humans and other animals.	Glycine	4-7	gamma-glutamylcyclotransferase	Homo sapiens	13-16
31070104-5	2019	Twelve loci were significantly associated with circulating glycine levels, 7 of which were not previously known to be involved in glycine metabolism ( ACADM , PHGDH , COX 18- ADAMTS 3, PSPH , TRIB 1, PTPRD , and ABO ).	Glycine	59-66	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase	Homo sapiens	212-215
8208364-5	1994	The cytoplasmic region of frog synaptophysin is also rich in glutamine and glycine residues, but the putative consensus repeating sequence Tyr-Gly-Pro/Gln-Gln-Gly in mammalian synaptophysins does not occur in the frog protein.	Glycine	75-82	synaptophysin	Homo sapiens	31-44
8208364-5	1994	The cytoplasmic region of frog synaptophysin is also rich in glutamine and glycine residues, but the putative consensus repeating sequence Tyr-Gly-Pro/Gln-Gln-Gly in mammalian synaptophysins does not occur in the frog protein.	Glycine	143-146	synaptophysin	Homo sapiens	31-44
8631326-6	1996	Protein mass fingerprinting with tryptic fragments identified p57 as a protein related to protein disulfide-isomerase which belongs to the superfamily of Cys-Gly-His-Cys-containing sequences.	Glycine	158-161	prolyl 4-hydroxylase subunit beta	Rattus norvegicus	90-117
8772521-0	1996	Glycine-extended gastrin potentiates gastrin-stimulated gastric acid secretion in rats.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
8772521-0	1996	Glycine-extended gastrin potentiates gastrin-stimulated gastric acid secretion in rats.	Glycine	0-7	gastrin	Rattus norvegicus	37-44
8208364-5	1994	The cytoplasmic region of frog synaptophysin is also rich in glutamine and glycine residues, but the putative consensus repeating sequence Tyr-Gly-Pro/Gln-Gln-Gly in mammalian synaptophysins does not occur in the frog protein.	Glycine	159-162	synaptophysin	Homo sapiens	31-44
31113850-0	2019	mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-beta1-induced collagen biosynthesis.	Glycine	77-84	activating transcription factor 4	Homo sapiens	21-25
8772521-1	1996	The purpose of this study was to examine whether an intermediate form of amidated gastrin, glycine-extended gastrin (Gly-G), can stimulate gastric acid secretion in conscious rats prepared with gastric fistulas.	Glycine	117-120	gastrin	Rattus norvegicus	82-89
8772521-1	1996	The purpose of this study was to examine whether an intermediate form of amidated gastrin, glycine-extended gastrin (Gly-G), can stimulate gastric acid secretion in conscious rats prepared with gastric fistulas.	Glycine	117-120	gastrin	Rattus norvegicus	108-115
31113850-4	2019	Here, we showed that transforming growth factor-beta1 (TGF-beta1), the key pro-fibrotic cytokine implicated in multiple fibrotic conditions, increased the production of activating transcription factor 4 (ATF4), the transcriptional master regulator of amino acid metabolism, to supply glucose-derived glycine to meet the amino acid requirements associated with enhanced collagen production in response to myofibroblast differentiation.	Glycine	300-307	activating transcription factor 4	Homo sapiens	169-202
8043068-4	1994	The precursor for adrenomedullin (preproadrenomedullin) is 188 amino acids in length, including the adrenomedullin sequence, followed by a glycine (the amide donor).	Glycine	139-146	adrenomedullin	Homo sapiens	34-54
31113850-4	2019	Here, we showed that transforming growth factor-beta1 (TGF-beta1), the key pro-fibrotic cytokine implicated in multiple fibrotic conditions, increased the production of activating transcription factor 4 (ATF4), the transcriptional master regulator of amino acid metabolism, to supply glucose-derived glycine to meet the amino acid requirements associated with enhanced collagen production in response to myofibroblast differentiation.	Glycine	300-307	activating transcription factor 4	Homo sapiens	204-208
9062068-2	1996	Drastic changes in the CD and fluorescence spectra of oxytocin [cyclo(Cys1-Tyr2-Ile3-Gln4-Asn5-Cys6)-Pro7-Leu8-Gly 9-NH2] occur on binding Ca2+ in trifluoroethanol (Ananthanarayanan and Brimble, preceding paper).	Glycine	111-114	oxytocin/neurophysin I prepropeptide	Homo sapiens	54-62
31113850-6	2019	ATF4, in turn, promoted the transcription of genes encoding enzymes of the de novo serine-glycine biosynthetic pathway and glucose transporter 1 (GLUT1).	Glycine	90-97	activating transcription factor 4	Homo sapiens	0-4
31113850-6	2019	ATF4, in turn, promoted the transcription of genes encoding enzymes of the de novo serine-glycine biosynthetic pathway and glucose transporter 1 (GLUT1).	Glycine	90-97	solute carrier family 2 member 1	Homo sapiens	123-144
8289288-6	1994	Type I and II turn conformations of the Aib compound have similar free energy; the Val compound is most stable in a type I turn conformation (by 8 kJ/mol), while the Gly compound is most stable in a type II turn conformation (by 5 kJ/mol).	Glycine	166-169	ANIB1	Homo sapiens	40-43
31113850-6	2019	ATF4, in turn, promoted the transcription of genes encoding enzymes of the de novo serine-glycine biosynthetic pathway and glucose transporter 1 (GLUT1).	Glycine	90-97	solute carrier family 2 member 1	Homo sapiens	146-151
30746902-2	2019	Our results showed that gly-HDL caused macrophage apoptosis with concomitant activation of ER stress pathway, including nuclear translocation of activating transcription factor 6, phosphorylation of protein kinase-like ER kinase (PERK) and eukaryotic translation initiation factor 2alpha, and CHOP up-regulation, which were inhibited by 4-phenylbutyric acid (PBA, an ER stress inhibitor) and the gene silencing of PERK and CHOP.	Glycine	24-27	eukaryotic translation initiation factor 2A	Homo sapiens	240-287
8309846-3	1994	Glycine infusions resulted in a four-fold increase and saline in a doubling of the plasma ANP concentration, despite a more pronounced volume expansion from saline.	Glycine	0-7	natriuretic peptides A	Ovis aries	90-93
7576181-5	1995	This nucleotide changes from G to A, causing amino acid residue 187 to change from glycine (GGC) to serine (AGC).	Glycine	83-90	gamma-glutamylcyclotransferase	Homo sapiens	92-95
30746902-4	2019	Gly-HDL induced macrophage autophagy as assessed by up-regulation of beclin-1, autophagy-related gene 5 and microtubule-associated protein one light chain 3-II, which were depressed by PBA and PERK siRNA.	Glycine	0-3	beclin 1	Homo sapiens	69-138
30746902-5	2019	Gly-HDL-induced apoptosis, PERK phosphorylation and CHOP up-regulation were suppressed by rapamycin (an autophagy inducer), whereas aggravated by 3-methyladenine (an autophagy inhibitor) and beclin-1 siRNA.	Glycine	0-3	beclin 1	Homo sapiens	191-199
30942159-4	2019	Targeted exome sequencing, conducted using DNA samples of an affected member in this family, revealed a novel heterozygous missense mutation c.1855T&amp;gt;G in exon 20 of EYA4, causing amino-acid (aa) substitution Gly for Trp at a conserved position aa-619.	Glycine	215-218	EYA transcriptional coactivator and phosphatase 4	Homo sapiens	172-176
7566152-3	1995	Here we report the isolation, on the basis of its ability to inhibit the cyclase in a stable recombinant CHO(ORL1+) cell line, of a neuropeptide that resembles dynorphin A9 and whose amino acid sequence is Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln.	Glycine	210-213	opioid receptor-like 1	Mus musculus	109-113
7548083-5	1995	In the present study, high-resolution 15N NMR at 50.6 MHz was used to directly measure the pKa values of the amino groups of the Gly-1, Lys-7, Lys-21, and Lys-23 residues of MLT.	Glycine	129-132	melittin	Apis mellifera	174-177
7548083-6	1995	Specifically, the pH dependence of MLT 15N chemical shifts was measured separately for the isotopically enriched backbone nitrogen of Gly-1 and the side chain nitrogen atoms of Lys-7, Lys-21, and Lys-23 at a MLT concentration of 1.2 mM and a temperature of 23 degrees C. Measurements were made for MLT in potassium phosphate buffer, in neat water, and in 1-myristoyl-2-hydroxyl-sn-glycero-3-phosphocholine (MMPC) lipid micelles.	Glycine	134-137	melittin	Apis mellifera	35-38
8309846-4	1994	The ANP level remained significantly elevated for 2 hr after glycine infusion.	Glycine	61-68	natriuretic peptides A	Ovis aries	4-7
8309846-5	1994	This result suggests that glycine has a specific ANP-stimulating effect which may contribute to the hypovolemia, hypotension, and natriuresis seen in the "transurethral resection (TUR) syndrome."	Glycine	26-33	natriuretic peptides A	Ovis aries	49-52
8144351-4	1993	The Val->Gly replacement at position beta 18 (codon 18; GTG->GGG) or at the last position of the A helix decreases the stability of the variant without affecting the hematological parameters of its carrier.	Glycine	9-12	gamma-glutamyltransferase 1	Homo sapiens	56-59
30465710-3	2019	We found that a leucine to glycine mutation at the Y+3 position after the first ITAM tyrosine prevents Syk binding and activation.	Glycine	27-34	spleen associated tyrosine kinase	Homo sapiens	103-106
8309954-1	1993	The effects of endogenous opioid peptides are limited by proteolytic enzymes such as endopeptidase 24.11 ("enkephalinase"), which cleaves the Gly-Phe bonds in Met- and Leu-enkephalin.	Glycine	142-145	prodynorphin	Mus musculus	168-182
7510882-0	1993	N alpha-carboxyacyl analogues of CCK with a substituted Gly: interaction with pancreatic and gallbladder CCK receptors.	Glycine	56-59	cholecystokinin	Cavia porcellus	33-36
7510882-0	1993	N alpha-carboxyacyl analogues of CCK with a substituted Gly: interaction with pancreatic and gallbladder CCK receptors.	Glycine	56-59	cholecystokinin	Cavia porcellus	105-108
7496799-6	1995	Immunogold reactions showed that synaptic profiles apposed to gephyrin-immunoreactive junctions contained GABA and glycine.	Glycine	115-122	gephyrin	Felis catus	62-70
30907303-11	2019	Kynurenine aminotransferase-III is, so far, the most efficient putative mitochondrial enzyme to transaminate glyoxylate to glycine in mammalian livers, might be an interesting enzyme to look over in hyperoxaluria etiology of primary hyperoxaluria and should be carefully investigated for its involvement in oxalate metabolism.	Glycine	123-130	kynurenine aminotransferase 3	Homo sapiens	0-31
7601162-7	1995	The amino acid sequence derived from the nucleotide sequence revealed that pig transthyretin differs from the transthyretins of all other studied vertebrate species by an unusual C-terminal extension consisting of the amino acids glycine, alanine and leucine.	Glycine	230-237	transthyretin	Sus scrofa	79-92
7510882-1	1993	It has been reported that certain N alpha-carboxyacyl analogues of CCK-8 and of CCK-7 with a substituted Gly in position 3 or 4 of the peptide possess higher potencies at stimulating pancreatic enzyme secretion than at stimulating gallbladder contraction, suggesting that these analogues are able to differentiate subtypes of CCKA receptors.	Glycine	105-108	cholecystokinin	Cavia porcellus	67-70
7510882-1	1993	It has been reported that certain N alpha-carboxyacyl analogues of CCK-8 and of CCK-7 with a substituted Gly in position 3 or 4 of the peptide possess higher potencies at stimulating pancreatic enzyme secretion than at stimulating gallbladder contraction, suggesting that these analogues are able to differentiate subtypes of CCKA receptors.	Glycine	105-108	cholecystokinin	Cavia porcellus	80-83
7510882-7	1993	These data demonstrate that the CCKA receptors in the pancreas and on gallbladder smooth muscle possess similar affinities for the various N alpha-carboxyacyl analogues of CCK-7 and CCK-8 with a substituted Gly and provide further evidence that the CCKA receptors in gallbladder and pancreas cannot be distinguished pharmacologically.	Glycine	207-210	cholecystokinin	Cavia porcellus	32-35
7510882-7	1993	These data demonstrate that the CCKA receptors in the pancreas and on gallbladder smooth muscle possess similar affinities for the various N alpha-carboxyacyl analogues of CCK-7 and CCK-8 with a substituted Gly and provide further evidence that the CCKA receptors in gallbladder and pancreas cannot be distinguished pharmacologically.	Glycine	207-210	cholecystokinin	Cavia porcellus	172-175
30696582-9	2019	It is proposed that many of these effects may be attributable to glycine-mediated suppression of endosomal NADPH oxidase activity.	Glycine	65-72	2,4-dienoyl-CoA reductase 1	Homo sapiens	107-112
8415696-3	1993	The amino terminus of the predicted protein of glh-1 contains a set of glycine-rich repeats similar in location and sequence to those in the predicted vasa protein.	Glycine	71-78	ATP-dependent RNA helicase glh-1	Caenorhabditis elegans	47-52
8264990-4	1993	Hippocalcin is myristoylated at its NH2-terminal glycine residue, and this modification is a key event in terms of its membrane-association property.	Glycine	49-56	hippocalcin	Homo sapiens	0-11
7596817-1	1995	Several nucleolar proteins, such as nucleolin, NOP1/fibrillarin, SSB1, NSR1 and GAR1 share a common glycine and arginine rich structural motif called the GAR domain.	Glycine	100-107	Nsr1p	Saccharomyces cerevisiae S288C	71-75
7789952-1	1995	We determined that two siblings with type III osteogenesis imperfecta (OI) had the same single base substitution that converted the codon for glycine (Gly) 862 to a codon for serine (Ser) in exon 44 of the alpha 1 chain of the type I (alpha 1(I)) collagen gene (COL1A1).	Glycine	142-149	collagen type I alpha 1 chain	Homo sapiens	262-268
7789952-1	1995	We determined that two siblings with type III osteogenesis imperfecta (OI) had the same single base substitution that converted the codon for glycine (Gly) 862 to a codon for serine (Ser) in exon 44 of the alpha 1 chain of the type I (alpha 1(I)) collagen gene (COL1A1).	Glycine	151-154	collagen type I alpha 1 chain	Homo sapiens	262-268
7542253-7	1995	GRGDS (gly-arg-gly-asp-ser) peptides inhibited cell adhesion to intact GST-OPN, as well as to fibronectin and vitronectin.	Glycine	7-10	vitronectin	Mus musculus	110-121
7542253-7	1995	GRGDS (gly-arg-gly-asp-ser) peptides inhibited cell adhesion to intact GST-OPN, as well as to fibronectin and vitronectin.	Glycine	15-18	vitronectin	Mus musculus	110-121
30696582-10	2019	This model suggests that supplemental glycine may have utility for prevention and control of atherosclerosis, heart failure, angiogenesis associated with cancer or retinal disorders, and a range of inflammation-driven syndromes - including metabolic syndrome; and it might complement the suppression of NADPH oxidase activity achievable with phycocyanobilin-enriched spirulina extracts.	Glycine	38-45	2,4-dienoyl-CoA reductase 1	Homo sapiens	303-308
30455356-3	2019	CLIP-170 contains two N-terminal cytoskeleton-associated protein glycine-rich (CAP-Gly) domains flanked by serine-rich regions.	Glycine	65-72	CAP-Gly domain containing linker protein 1	Homo sapiens	0-8
7861014-3	1995	Examination of the polymerase chain reaction corresponding to exon 73 revealed a heteroduplex resulting from a G-to-A transition at nucleotide 6127 in the triple-helical domain of COL7A1, which converted a glycine residue to an arginine (G2043R).	Glycine	206-213	collagen type VII alpha 1 chain	Homo sapiens	180-186
7833467-11	1995	By comparing the coding area of the gpFy gene in 28 Duffy-positive individuals, we elucidated that one base change that results in an amino acid substitution [GA-T(Asp44)-->GGT(Gly)] is in accordance with the Fya/Fyb polymorphism.	Glycine	177-180	atypical chemokine receptor 1 (Duffy blood group)	Homo sapiens	36-40
8344932-6	1993	Analysis of the amino acid composition of elastin-derived peptide indicates the presence of alanine, glycine, and richness in hydrophobic residues, suggesting that these residues are involved in elastase interaction(s).	Glycine	101-108	elastin	Homo sapiens	42-49
30455356-3	2019	CLIP-170 contains two N-terminal cytoskeleton-associated protein glycine-rich (CAP-Gly) domains flanked by serine-rich regions.	Glycine	83-86	CAP-Gly domain containing linker protein 1	Homo sapiens	0-8
30455356-4	2019	The CAP-Gly domains are known EB1-binding domains, and the serine-rich regions have also been implicated in CLIP-170"s microtubule plus-end localization mechanism.	Glycine	8-11	microtubule associated protein RP/EB family member 1	Homo sapiens	30-33
30455356-4	2019	The CAP-Gly domains are known EB1-binding domains, and the serine-rich regions have also been implicated in CLIP-170"s microtubule plus-end localization mechanism.	Glycine	8-11	CAP-Gly domain containing linker protein 1	Homo sapiens	108-116
30455356-7	2019	Using isothermal titration calorimetry and size-exclusion chromatography, we mapped and biophysically characterized these EB1-binding modules, including the two CAP-Gly domains, a bridging SXIP motif, and a unique array of divergent SXIP-like motifs located N-terminally to the first CAP-Gly domain.	Glycine	165-168	microtubule associated protein RP/EB family member 1	Homo sapiens	122-125
7738104-12	1995	NPL3 includes bipartite RNA recognition motifs (RRM) and a Gly-Arg repeat domain, as in several nucleolar proteins.	Glycine	59-62	mRNA-binding protein NPL3	Saccharomyces cerevisiae S288C	0-4
30455356-7	2019	Using isothermal titration calorimetry and size-exclusion chromatography, we mapped and biophysically characterized these EB1-binding modules, including the two CAP-Gly domains, a bridging SXIP motif, and a unique array of divergent SXIP-like motifs located N-terminally to the first CAP-Gly domain.	Glycine	288-291	microtubule associated protein RP/EB family member 1	Homo sapiens	122-125
30455356-8	2019	We found that, unlike the EB1-binding mode of the CAP-Gly domain in the dynactin-associated protein p150Glued, which dually engages the EB1 C-terminal EEY motif as well as the EB homology domain and sterically occludes SXIP motif binding, the CLIP-170 CAP-Gly domains engage only the EEY motif, enabling the flanking SXIP and SXIP-like motifs to bind the EB homology domain.	Glycine	54-57	microtubule associated protein RP/EB family member 1	Homo sapiens	26-29
30455356-8	2019	We found that, unlike the EB1-binding mode of the CAP-Gly domain in the dynactin-associated protein p150Glued, which dually engages the EB1 C-terminal EEY motif as well as the EB homology domain and sterically occludes SXIP motif binding, the CLIP-170 CAP-Gly domains engage only the EEY motif, enabling the flanking SXIP and SXIP-like motifs to bind the EB homology domain.	Glycine	54-57	microtubule associated protein RP/EB family member 1	Homo sapiens	136-139
30455356-8	2019	We found that, unlike the EB1-binding mode of the CAP-Gly domain in the dynactin-associated protein p150Glued, which dually engages the EB1 C-terminal EEY motif as well as the EB homology domain and sterically occludes SXIP motif binding, the CLIP-170 CAP-Gly domains engage only the EEY motif, enabling the flanking SXIP and SXIP-like motifs to bind the EB homology domain.	Glycine	54-57	CAP-Gly domain containing linker protein 1	Homo sapiens	243-251
30455356-10	2019	Our finding that CLIP-170 has multiple non-CAP-Gly EB1-binding modules may explain why autoinhibition of CLIP-170 GAP-Gly domains does not fully abrogate its microtubule plus-end localization.	Glycine	47-50	CAP-Gly domain containing linker protein 1	Homo sapiens	17-25
7898680-5	1994	In the remainder of the spinal cord, between 21 and 35% of the c-fos-immunoreactive cells were GABA- or glycine-immunoreactive, and the majority of these neurons contained both types of immunoreactivity.	Glycine	104-111	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	63-68
7720110-3	1994	The result showed that mutation of both cell lines occurred on the 154th codon in exon5 of p53 gene, where GGC was displaced by GTC resulting a substitution of Val for Gly, nevertheless, N-ras oncogene and the exon7 of p53 gene are normal.	Glycine	168-171	gamma-glutamylcyclotransferase	Homo sapiens	107-110
30524262-3	2018	In the brainstem and spinal cord, GABA and glycine cotransmission is facilitated by a shared vesicular transporter VIAAT (also named VGAT), and occurs at many immature inhibitory synapses.	Glycine	43-50	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	115-120
7971977-3	1994	As for NR1(011) homomers, NR1(011)/NR2B receptors exhibited spermine potentiation by two mechanisms: by increasing glycine affinity and by increasing current through receptors with bound N-methyl-D-aspartate and glycine.	Glycine	115-122	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	35-39
7971977-3	1994	As for NR1(011) homomers, NR1(011)/NR2B receptors exhibited spermine potentiation by two mechanisms: by increasing glycine affinity and by increasing current through receptors with bound N-methyl-D-aspartate and glycine.	Glycine	212-219	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	35-39
30524262-3	2018	In the brainstem and spinal cord, GABA and glycine cotransmission is facilitated by a shared vesicular transporter VIAAT (also named VGAT), and occurs at many immature inhibitory synapses.	Glycine	43-50	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	133-137
21559673-9	1994	AOM-induced G to A transitions were observed at the second nucleotide of 12th codon of K-ras substituting amino acid asp with wild-type gly.	Glycine	136-139	KRAS proto-oncogene, GTPase	Rattus norvegicus	87-92
29886015-5	2018	Monomeric elastin is a non-polar, glycine-rich, low-complexity, modular protein that remains predominantly disordered even in the crosslinked polymeric state, consistent with its function as an entropic elastomer.	Glycine	34-41	elastin	Homo sapiens	10-17
7703855-0	1994	The role of glycine (residue 89) in the central helix of EF-hand protein troponin-C exposed following amino-terminal alpha-helix deletion.	Glycine	12-19	tenascin C	Homo sapiens	73-83
7703855-8	1994	The findings indicate a destabilizing influence of Gly-89 residue in skeletal TnC and suggest that the N-terminal arm in normal TnC serves to moderate this effect.	Glycine	51-54	tenascin C	Homo sapiens	78-81
7800847-5	1994	The corrected primary structure of chicken PP is therefore: Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asp- Ala-Pro-Val-Glu-Asp-Leu-Ile-Arg- Phe-Tyr-Asn-Asp-Leu-Gln-Gln-Tyr-Leu-Asn-Val-Val-Thr-Arg-His-Arg-Tyr-NH2.	Glycine	60-63	pancreatic hormone	Gallus gallus	43-45
30138575-9	2018	In contrast to in vivo experiments, robust Gly-Sar-induced Isc increments were observed in the jejunal mucosa of cldn15-/- mice.	Glycine	43-46	claudin 15	Mus musculus	113-119
8052270-8	1994	Position 615 is glutamic acid in UVL-13 and glycine in AA8, and the corresponding positions of XPD, RAD3, and rad15 are glycine.	Glycine	120-127	TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3	Saccharomyces cerevisiae S288C	100-104
30105462-3	2018	BRCA1 c.5309G&gt;T p.(Gly1770Val) has been shown to abrogate BRCA1 protein homologous DNA repair; however, multiple sequence alignment demonstrates a lack of sequence conservation at this position, suggesting that glycine at position 1770 may not be essential for cellular maintenance in humans.	Glycine	214-221	BRCA1 DNA repair associated	Homo sapiens	0-5
8036014-2	1994	It contains a functional gly-arg-gly-asp-ser (GRGDS) integrin binding domain (Oldberg et al., 1986), promotes the adhesion of a variety of cell types (Somerman et al., 1989; Brown et al., 1992) and is a ligand for the vitronectin binding integrin alpha v beta 3 (Miyauchi et al., 1991).	Glycine	25-28	vitronectin	Homo sapiens	218-229
8036014-2	1994	It contains a functional gly-arg-gly-asp-ser (GRGDS) integrin binding domain (Oldberg et al., 1986), promotes the adhesion of a variety of cell types (Somerman et al., 1989; Brown et al., 1992) and is a ligand for the vitronectin binding integrin alpha v beta 3 (Miyauchi et al., 1991).	Glycine	25-28	integrin subunit alpha V	Homo sapiens	238-261
8036014-2	1994	It contains a functional gly-arg-gly-asp-ser (GRGDS) integrin binding domain (Oldberg et al., 1986), promotes the adhesion of a variety of cell types (Somerman et al., 1989; Brown et al., 1992) and is a ligand for the vitronectin binding integrin alpha v beta 3 (Miyauchi et al., 1991).	Glycine	33-36	vitronectin	Homo sapiens	218-229
8036014-2	1994	It contains a functional gly-arg-gly-asp-ser (GRGDS) integrin binding domain (Oldberg et al., 1986), promotes the adhesion of a variety of cell types (Somerman et al., 1989; Brown et al., 1992) and is a ligand for the vitronectin binding integrin alpha v beta 3 (Miyauchi et al., 1991).	Glycine	33-36	integrin subunit alpha V	Homo sapiens	238-261
7972490-2	1994	The cDNA library was made from poly(A)+ RNA from leaves challenged with mercuric chloride for 2 d. The two clones, pCh2 and pCh11, appear to encode class I chitinase isoforms with cysteine-rich domains (not found in pCh11 due to the incomplete sequence) and proline-/glycine-rich or proline-rich hinge domains, respectively.	Glycine	267-274	LOW QUALITY PROTEIN: basic endochitinase A	Zea mays	124-129
30105462-3	2018	BRCA1 c.5309G&gt;T p.(Gly1770Val) has been shown to abrogate BRCA1 protein homologous DNA repair; however, multiple sequence alignment demonstrates a lack of sequence conservation at this position, suggesting that glycine at position 1770 may not be essential for cellular maintenance in humans.	Glycine	214-221	BRCA1 DNA repair associated	Homo sapiens	61-66
30265669-4	2018	Here, we have identified a single glycine residue in the CED-10/Rac1 Switch 1 region that confers a non-redundant function in axon outgrowth but not guidance.	Glycine	34-41	Ras-related protein ced-10	Caenorhabditis elegans	57-63
8041367-11	1994	Sequence analysis of this region revealed that the GGT codon encoding Gly-1257 of the FAS2 gene was altered to AGT in the mutant, resulting in the codon for Ser.	Glycine	70-73	trifunctional fatty acid synthase subunit FAS2	Saccharomyces cerevisiae S288C	86-90
31819726-3	2018	The transcription level of the CaMV 35S promoter driven-codA was more than fourfold higher, and the content of glycine betaine, the metabolic product of codA, was twofold higher, with the HSP terminator than with the nopaline synthase (NOS) terminator.	Glycine	111-118	heat shock protein	Arabidopsis thaliana	188-191
8024578-1	1994	An amino acid sequence (Arg-Gly-Asp-Val) specifically associating with cell adhesion between cells and extracellular matrices was found on the human Zn-alpha 2-glycoprotein (Zn alpha 2gp) molecule.	Glycine	28-31	alpha-2-glycoprotein 1, zinc-binding	Homo sapiens	149-172
30283487-10	2018	The effect of ETHE1 knock-down on amino acid profiles was clearly different from that found in leaves indicating that in seeds persulfide oxidation interacts with alanine and glycine rather than branched-chain amino acid metabolism.	Glycine	175-182	glyoxalase II 3	Arabidopsis thaliana	14-19
8024578-1	1994	An amino acid sequence (Arg-Gly-Asp-Val) specifically associating with cell adhesion between cells and extracellular matrices was found on the human Zn-alpha 2-glycoprotein (Zn alpha 2gp) molecule.	Glycine	28-31	alpha-2-glycoprotein 1, zinc-binding	Homo sapiens	174-186
8198547-2	1994	Peptidylglycine alpha-amidating mono-oxygenase (PAM; EC 1.14.17.3) catalyses conversion of glycine-extended peptide hormone precursors into their corresponding alpha-hydroxyglycine derivatives.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	48-51
30217974-5	2018	The SPs of TRAP clients exhibit above-average glycine-plus-proline content and below-average hydrophobicity as distinguishing features.	Glycine	46-53	TRAP	Homo sapiens	11-15
8176259-8	1994	Pan ras antibody against mutated p21 at codon 12 showed very strong reactivity for ras val-12p21 in tumors but not in normal epidermis, suggesting a gly to val substitution at 12th position in ras p21 in UVB-induced tumors.	Glycine	149-152	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	33-36
8176259-8	1994	Pan ras antibody against mutated p21 at codon 12 showed very strong reactivity for ras val-12p21 in tumors but not in normal epidermis, suggesting a gly to val substitution at 12th position in ras p21 in UVB-induced tumors.	Glycine	149-152	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	93-96
30217974-6	2018	Thus, TRAP may act as SP receptor on the ER membrane"s cytosolic face, recognizing precursor polypeptides with SPs of high glycine-plus-proline content and/or low hydrophobicity, and triggering substrate-specific opening of the Sec61 channel through interactions with the ER-lumenal hinge of Sec61alpha.	Glycine	123-130	TRAP	Homo sapiens	6-10
8190097-7	1994	Glycine-dependent stimulation was seen at NR1A/NR2A and NR1A/NR2B receptors and may therefore involve a second polyamine binding site distinct from that which produces glycine-independent stimulation.	Glycine	0-7	nodal homolog 1 L homeolog	Xenopus laevis	42-46
30006415-7	2018	The complex structure of MAGI1-PDZ3/nephrin-PBM reveals that the Gly at the -3 position of nephrin-PBM is the determining feature for MAGI1-PDZ3 recognition, which sharply contrasts with the typical PDZ/PBM binding mode.	Glycine	65-68	NPHS1 adhesion molecule, nephrin	Homo sapiens	36-43
8190097-7	1994	Glycine-dependent stimulation was seen at NR1A/NR2A and NR1A/NR2B receptors and may therefore involve a second polyamine binding site distinct from that which produces glycine-independent stimulation.	Glycine	0-7	nodal homolog 1 L homeolog	Xenopus laevis	56-60
8183239-8	1994	When expressed in COS-7 cells, both the human GlyT-1b and GlyT-1c display a time- and dose-dependent uptake of glycine, which is abolished when either Na+ or Cl- is substituted with other ions.	Glycine	111-118	solute carrier family 6 member 9	Rattus norvegicus	46-53
8183239-9	1994	For both GlyT-1b and GlyT-1c the affinities for glycine are similar, with Km values of 70-90 microM, and this uptake is inhibited by sarcosine with similar potencies.	Glycine	48-55	solute carrier family 6 member 9	Rattus norvegicus	9-16
7511781-4	1994	Expression of NR-1a alone produced glycine antagonist binding, whereas the combination of NR-1a and NR-2A was needed to produce binding sites for glutamate antagonists and channel-blocking agents.	Glycine	35-42	nodal homolog 1 L homeolog	Xenopus laevis	14-19
30006415-7	2018	The complex structure of MAGI1-PDZ3/nephrin-PBM reveals that the Gly at the -3 position of nephrin-PBM is the determining feature for MAGI1-PDZ3 recognition, which sharply contrasts with the typical PDZ/PBM binding mode.	Glycine	65-68	NPHS1 adhesion molecule, nephrin	Homo sapiens	91-98
30228815-1	2018	Background and Objective: Serine hydroxymethyltransferase 2 (SHMT2) functions as a key enzyme in serine/glycine biosynthesis and one-carbon metabolism.	Glycine	104-111	serine hydroxymethyltransferase 2	Homo sapiens	26-59
8106519-3	1994	Nmt1p catalyzes the co-translational transfer of myristate from CoA to the amino-terminal Gly of cellular proteins in an ordered Bi Bi reaction mechanism that initially involves binding of myristoyl-CoA to the apoenzyme.	Glycine	90-93	glycylpeptide N-tetradecanoyltransferase NMT1	Saccharomyces cerevisiae S288C	0-5
8159808-5	1994	Although, we detected substantial amounts of glycine-extended CCK in the proximal rat duodenum, we detected none of the corresponding amidated molecular forms.	Glycine	45-52	cholecystokinin	Rattus norvegicus	62-65
7905794-0	1994	Inhibition of CD4+ T lymphocyte binding to fibronectin and immune-cell accumulation in inflammatory sites by non-peptidic mimetics of Arg-Gly-Asp.	Glycine	138-141	CD4 antigen	Mus musculus	14-17
30228815-1	2018	Background and Objective: Serine hydroxymethyltransferase 2 (SHMT2) functions as a key enzyme in serine/glycine biosynthesis and one-carbon metabolism.	Glycine	104-111	serine hydroxymethyltransferase 2	Homo sapiens	61-66
29987032-5	2018	We report that the physiologically relevant LIPT1 enzyme activity is transfer of lipoyl moieties from the H protein of the glycine cleavage system to the E2 subunits of the 2-oxoacid dehydrogenases required for respiration (e.g., pyruvate dehydrogenase) and amino acid degradation.	Glycine	123-130	lipoyltransferase 1	Homo sapiens	44-49
8300631-13	1994	A Gly--&gt;Asp mutation in S. cerevisiae, C. neoformans, C. albicans, and H. sapiens Nmts produces temperature-sensitive growth arrest in isogenic S. cerevisiae strains with a nmt1 null allele.	Glycine	2-5	glycylpeptide N-tetradecanoyltransferase NMT1	Saccharomyces cerevisiae S288C	176-180
8276845-14	1994	The VCS-beta 1 cDNA codes for a proline-rich protein precursor named PR-V beta 1 (148 amino acids, 39.2% proline, 10.8% glycine) and characterized by a secretory signal-peptide and three repeats of a unit rich in proline residues surrounded by two clusters of potential endoprotease cleavage sites.	Glycine	120-127	proline rich protein 2-like 1	Rattus norvegicus	32-52
8350871-5	1993	The results of the mutagenesis showed that changing a single light chain residue, VL 91, from glycine to aspartic acid, resulted in a dramatic loss of Ars binding activity.	Glycine	94-101	secreted Ly6/Plaur domain containing 1	Mus musculus	151-154
30237684-6	2018	In silico molecular docking of (1-6) into dCK revealed good interactions, where interesting hydrogen bonds were observed with the amino acid residues-Gly-28 and Ser-35-located in the highly conserved P-loop motif.	Glycine	150-153	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	42-45
7688509-1	1993	An anti-peptide antibody was raised against the sequence Thr-Gly-Ala-Leu-Phe-Lys-His-Ser-Glu-Asn-Tyr-Lys which occurs at positions 283-294 in the rat cytochrome P450 enzyme CYP1A2.	Glycine	61-64	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	173-179
8974336-2	1994	Previous work, using primary cultures of rat cerebellar granule cells, showed that both exposure to alcohol and activation of protein kinase C (PKC) by the phorbol ester PMA reduced the potency of the co-agonist, glycine, to enhance NMDA receptor function (measured as an increase in intracellular Ca2+), resulting in inhibition of the NMDA response at low glycine concentrations.	Glycine	213-220	protein kinase C, gamma	Rattus norvegicus	126-142
8974336-2	1994	Previous work, using primary cultures of rat cerebellar granule cells, showed that both exposure to alcohol and activation of protein kinase C (PKC) by the phorbol ester PMA reduced the potency of the co-agonist, glycine, to enhance NMDA receptor function (measured as an increase in intracellular Ca2+), resulting in inhibition of the NMDA response at low glycine concentrations.	Glycine	213-220	protein kinase C, gamma	Rattus norvegicus	144-147
8974336-2	1994	Previous work, using primary cultures of rat cerebellar granule cells, showed that both exposure to alcohol and activation of protein kinase C (PKC) by the phorbol ester PMA reduced the potency of the co-agonist, glycine, to enhance NMDA receptor function (measured as an increase in intracellular Ca2+), resulting in inhibition of the NMDA response at low glycine concentrations.	Glycine	357-364	protein kinase C, gamma	Rattus norvegicus	126-142
30271955-2	2018	Peptidylglycine alpha-hydroxylating monooxygenase (PHM) is a dicopper enzyme that catalyzes hydroxylation of the alpha-carbon of glycine-extended peptides for the formation of des-glycine amidated peptides.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	51-54
8974336-2	1994	Previous work, using primary cultures of rat cerebellar granule cells, showed that both exposure to alcohol and activation of protein kinase C (PKC) by the phorbol ester PMA reduced the potency of the co-agonist, glycine, to enhance NMDA receptor function (measured as an increase in intracellular Ca2+), resulting in inhibition of the NMDA response at low glycine concentrations.	Glycine	357-364	protein kinase C, gamma	Rattus norvegicus	144-147
7903250-6	1993	Through genetic remodeling techniques, we now show that ARM-Gly505 in ANF-RGC and the corresponding ARM-Gly499 in CNP-RGC are critical for ANF and CNP signaling, and other ARM-Gly residues have minimal effect in the respective signaling processes.	Glycine	60-63	natriuretic peptide C	Homo sapiens	114-117
7903250-6	1993	Through genetic remodeling techniques, we now show that ARM-Gly505 in ANF-RGC and the corresponding ARM-Gly499 in CNP-RGC are critical for ANF and CNP signaling, and other ARM-Gly residues have minimal effect in the respective signaling processes.	Glycine	60-63	natriuretic peptide C	Homo sapiens	147-150
8219225-5	1993	Within this region, the mu-PAR domain 1 could be minimally humanized to bind human pro-u-PA by a substitution of as few as four of the six nonconserved residues, thereby identifying the residues arginine-2, lysine-7, threonine-8, and glycine-10 as important in determining binding specificity.	Glycine	234-241	jumping translocation breakpoint	Homo sapiens	27-30
8334153-11	1993	Amino acid analysis showed that Gly, Thr, and Ser residues in FABP-I were almost twice as high as in FABP-II.	Glycine	32-35	fatty acid binding protein 2	Rattus norvegicus	62-68
8334153-11	1993	Amino acid analysis showed that Gly, Thr, and Ser residues in FABP-I were almost twice as high as in FABP-II.	Glycine	32-35	fatty acid binding protein 2	Rattus norvegicus	62-66
8233617-1	1993	Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum is characterized by the presence of an amino acid motif based on the sequence Trp-Ser-Pro-Cys-Ser-Val-Thr-Cys-Gly (WSPCSVTCG) that is found in a growing family of proteins.	Glycine	183-186	TRAP	Homo sapiens	42-46
29698679-0	2018	Glycine confers neuroprotection through PTEN/AKT signal pathway in experimental intracerebral hemorrhage.	Glycine	0-7	phosphatase and tensin homolog	Rattus norvegicus	40-44
8481514-4	1993	Analysis of the genes for two other components of the platelet GPIb:IX complex, namely GPIb beta and GPIX, showed two different missense mutations in the coding region of the GPIX gene: an A-->G transition in codon 21 results in conversion of an aspartic acid to glycine and an A-->G change in codon 45 converts an asparagine residue to serine.	Glycine	263-270	glycoprotein Ib platelet subunit alpha	Homo sapiens	87-96
8221663-3	1993	Further analysis of 14 ES and related primary tumors showed mutations of the p53 gene in only two: one base insertion of CCG--&gt;CCCG at codon 152 in one and a missense mutation of GGC (Gly)--&gt;GTC (Val) at codon 154 in the other.	Glycine	187-190	gamma-glutamylcyclotransferase	Homo sapiens	182-185
8287052-1	1993	Synthetic peptide analogues of the Arg-Gly-Asp-Ser (RGDS) sequence of fibronectin in which the amino acid of Gly was substituted with another one, named X, i.e. Arg-X-Asp-Ser (R-X-DS), and N-terminal modified R-X-DS have been synthesized to examine their antimetastatic effects in murine lung or liver metastasis models, as well as the inhibitory effect on tumor cell invasion, migration and adhesion in vitro.	Glycine	39-42	ral guanine nucleotide dissociation stimulator	Mus musculus	52-56
29698679-8	2018	However, glycine treatment decreased PTEN protein level and increased the phosphorylation level of AKT (p-AKT) in the perihematomal area.	Glycine	9-16	phosphatase and tensin homolog	Rattus norvegicus	37-41
29698679-12	2018	Together, our findings demonstrate, for the first time, the protective role of glycine on ICH rats, and suggest that the neuroprotective effect of glycine was mediated through PTEN/Akt signal pathway.	Glycine	147-154	phosphatase and tensin homolog	Rattus norvegicus	176-180
7690587-2	1993	Single amino acid variants of bovine pancreatic trypsin inhibitor (BPTI) have been made with glycine or alanine replacement of residues Tyr 35, Gly 37, Asn 43, and Asn 44.	Glycine	144-147	spleen trypsin inhibitor I	Bos taurus	67-71
29895827-2	2018	Here we show that oxPAPC induce a gene network regulating serine-glycine metabolism with the mitochondrial methylenetetrahydrofolate dehydrogenase/cyclohydrolase (MTHFD2) as a causal regulator using integrative network modeling and Bayesian network analysis in human aortic endothelial cells.	Glycine	65-72	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	163-169
8025347-10	1993	The "ligand-binding pocket" of GP IIb-IIIa contains at least three sequences essential for ligand binding; fibrinogen also binds to the activated complex through identified domains, one of which, the Arg-Gly-Asp (RGD) sequence, is also found in vWF and the other adhesive proteins able to support platelet aggregation.	Glycine	204-207	integrin subunit alpha 2b	Homo sapiens	31-37
8494645-5	1993	The anatomic distribution of GLYT-2 mRNA supports the emerging status of glycine as a supraspinal neurotransmitter and suggests that glycine may function as a chemical messenger outside the CNS.	Glycine	73-80	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	29-35
8494645-5	1993	The anatomic distribution of GLYT-2 mRNA supports the emerging status of glycine as a supraspinal neurotransmitter and suggests that glycine may function as a chemical messenger outside the CNS.	Glycine	133-140	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	29-35
8400548-1	1993	Previous studies have shown that exogenous glycosphingolipids (GSLs) inhibit the adhesion of thrombin-activated platelets (TAP) to polystyrene plates coated with various RGD-ligands (where RGD is the peptide sequence Arg-Gly-Asp), suggesting that GSLs can modulate the platelet integrin receptor glycoprotein IIb-IIIa.	Glycine	221-224	coagulation factor II, thrombin	Bos taurus	93-101
29895827-5	2018	The MTHFD2-controlled cluster redirects metabolism to glycine synthesis to replenish purine nucleotides.	Glycine	54-61	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	4-10
8471773-4	1993	From these 43 samples, we have identified five different types of nucleotide substitutions in the G6PD gene: at cDNA 1388 from G to A (Arg to His); at cDNA 1376 from G to T (Arg to Leu); at cDNA 1024 from C to T (Leu to Phe); at cDNA 392 from G to T (Gly to Val); at cDNA 95 from A to G (His to Arg).	Glycine	251-254	glucose-6-phosphate dehydrogenase	Homo sapiens	98-102
29895827-7	2018	Accordingly, MTHFD2-dependent glycine synthesis is a prerequisite for angiogenesis.	Glycine	30-37	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	13-19
29895827-8	2018	Thus, we propose that endothelial cells undergo MTHFD2-mediated reprogramming toward serine-glycine and mitochondrial one-carbon metabolism to compensate for the loss of ATP in response to oxPAPC during atherosclerosis.	Glycine	92-99	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	48-54
8333874-6	1993	The CCK "A-conformation" has two reversals of the peptide chain so that the C alpha-atoms of the C-terminal pentapeptide appear at the corners of a nearly regular pentagon, and a distinct beta-II turn is centered at the N-terminal Tyr-Met-Gly-Trp fragment, the planes of the turn and the pentagon being almost perpendicular.	Glycine	239-242	cholecystokinin A receptor	Homo sapiens	4-10
8462797-7	1993	Glycine-extended gastrin and CCK were also present in the fetal colon, but towards adult life they decreased below 0.2 pmol/g.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
29550635-0	2018	Participation of the IKK-alpha/beta complex in the inhibition of the TNF-alpha/NF-kappaB pathway by glycine: Possible involvement of a membrane receptor specific to adipocytes.	Glycine	100-107	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	21-30
8362410-6	1993	In view of the published data on HLA class I nucleotide sequences, the antibody may recognize an antigeneic determinant including two amino acid residues, Asp-166 and Gly-167, in the alpha 2 helix of the class I molecule that are specific for A1, A23 and A24 so far analyzed.	Glycine	167-170	immunoglobulin kappa variable 2-23 (pseudogene)	Homo sapiens	255-258
29550635-5	2018	In this research, participation of the IKK-alpha/beta complex in the inhibition of the TNF-alpha/NF-kappaB pathway by glycine was evaluated and associated with the synthesis and secretion of inflammatory cytokines in 3T3-L1 adipocytes.	Glycine	118-125	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	39-48
8323294-5	1993	Like the other vertebrate SCPx proteins, the chicken protein contains a conserved Arg-Gly-Asp sequence and a cysteine residue in the N-terminus that aligns with the active site cysteine of Escherichia coli 3-ketoacyl-CoA thiolase, a protein that was previously shown to be homologous to vertebrate SCPx.	Glycine	86-89	sterol carrier protein 2	Gallus gallus	26-30
8463133-4	1993	The mutation consisted of a guanine-to-adenine transition in the first base of codon 13 of c-Ki-ras which replaced wild-type glycine with serine, indicating that a putative glycine-to-aspartic acid change is not necessarily the critical event for c-Ki-ras gene activation in codon 13.	Glycine	173-180	KRAS proto-oncogene, GTPase	Homo sapiens	91-99
29550635-7	2018	Glycine decreased the IKK-alpha/beta complex and the phosphorylation of NF-kappaB, diminishing the expression and secretion of IL-6 and TNF-alpha, but increasing that of adiponectin.	Glycine	0-7	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	22-31
8463133-4	1993	The mutation consisted of a guanine-to-adenine transition in the first base of codon 13 of c-Ki-ras which replaced wild-type glycine with serine, indicating that a putative glycine-to-aspartic acid change is not necessarily the critical event for c-Ki-ras gene activation in codon 13.	Glycine	173-180	KRAS proto-oncogene, GTPase	Homo sapiens	247-255
8102327-2	1993	This reaction is catalysed by peptidylglycine alpha-amidating mono-oxygenase (PAM, EC 1.14.17.3) which converts the glycine extended precursors on their carboxyl termini to the des-glycine amidated peptide products.	Glycine	38-45	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	78-81
29550635-10	2018	In conclusion, the reduction of TNF-alpha and IL-6 and suppression of the TNF-alpha/NF-kappaB pathway by glycine may be explained in part by inhibition of the IKK-alpha/beta complex, with a possible participation of GlyR in 3T3-L1 adipocytes.	Glycine	105-112	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	159-168
8413849-6	1993	Storage granules containing glycine-extended CCK were shown in SK-N-MCIXC cells using indirect immunofluorescence.	Glycine	28-35	cholecystokinin	Rattus norvegicus	45-48
29928487-8	2018	Nucleolin directly bound to TRA2beta4 exon 2 via the glycine/arginine-rich (GAR) domain.	Glycine	53-60	transformer 2 beta homolog	Homo sapiens	28-36
8388502-4	1993	Cellular transcription factor TBP contains three glutamine-glycine sites, at amino acids 12, 18, and 108.	Glycine	59-66	TATA-box binding protein	Homo sapiens	30-33
8430078-1	1993	Nmt1p (EC 2.3.1.97) catalyzes the transfer of myristate (C14:0) from coenzyme A to the N-terminal glycine residue of a variety of eukaryotic cellular and viral proteins.	Glycine	98-105	glycylpeptide N-tetradecanoyltransferase NMT1	Saccharomyces cerevisiae S288C	0-5
8388502-8	1993	An alanine at position P4 and a proline at position P2, proximal to the scissile glutamine-glycine pair, appear to be important for 3CPro-mediated cleavage of TBP.	Glycine	91-98	TATA-box binding protein	Homo sapiens	159-162
29791506-3	2018	Mass-spectrometry analysis of whole-cell extracts from 2D10 Jurkat T cells revealed that JIB-04 targets Serine Hydroxymethyltransferase 2 (SHMT2), a regulator of glycine biosynthesis and an adaptor for the BRCC36 K63Ub-specific deubiquitinase in the BRISC complex.	Glycine	162-169	serine hydroxymethyltransferase 2	Homo sapiens	104-137
7683657-0	1993	Site-directed mutagenesis of the arginine-glycine-aspartic acid in vitronectin abolishes cell adhesion.	Glycine	42-49	vitronectin	Homo sapiens	67-78
7683657-3	1993	Many cell adhesion ligands, including vitronectin, contain an Arg-Gly-Asp (RGD) sequence mediating, in part, the ligand-receptor interaction.	Glycine	66-69	vitronectin	Homo sapiens	38-49
8093615-2	1993	At variance with platelet alpha IIb beta 3 or endothelial cell alpha v beta 3 integrins, CD11b/CD18 interacts with a approximately 30-kDa plasmic fragment D (D30) of fibrinogen that lacks the Arg-Gly-Asp sequences in the A alpha chain and the carboxyl terminus of the gamma chain.	Glycine	196-199	integrin subunit alpha M	Homo sapiens	89-94
8093355-7	1993	This sequence is Gly-Xa-Xa-Xa-Gly, represented by Gly505-Ser-Asn-Tyr-Gly509 in the case of ANF-RGC ARM and by Gly499-Ser-Ser-Tyr-Gly503 in the CNP receptor guanylate cyclase ARM.	Glycine	17-20	natriuretic peptide C	Homo sapiens	143-146
8093355-7	1993	This sequence is Gly-Xa-Xa-Xa-Gly, represented by Gly505-Ser-Asn-Tyr-Gly509 in the case of ANF-RGC ARM and by Gly499-Ser-Ser-Tyr-Gly503 in the CNP receptor guanylate cyclase ARM.	Glycine	30-33	natriuretic peptide C	Homo sapiens	143-146
29791506-3	2018	Mass-spectrometry analysis of whole-cell extracts from 2D10 Jurkat T cells revealed that JIB-04 targets Serine Hydroxymethyltransferase 2 (SHMT2), a regulator of glycine biosynthesis and an adaptor for the BRCC36 K63Ub-specific deubiquitinase in the BRISC complex.	Glycine	162-169	serine hydroxymethyltransferase 2	Homo sapiens	139-144
29481666-4	2018	Gene-based tests identified two novel genes harboring missense variants of MAF &lt;1% that show aggregate association with amino acid levels: PYCR1 with glycine (Pgene = 1.5x10-6) and BCAT2 with valine (Pgene = 7.4x10-7); neither gene was implicated by single variant association tests.	Glycine	153-160	pyrroline-5-carboxylate reductase 1	Homo sapiens	142-147
8417803-0	1993	Arg-Gly-Asp-dependent occupancy of GPIIb/IIIa by applaggin: evidence for internalization and cycling of a platelet integrin.	Glycine	4-7	integrin subunit alpha 2b	Homo sapiens	35-40
8320368-7	1993	The 60 kDa protein was found to be bovine osteopontin, a very highly phosphorylated protein with an Arg-Gly-Asp sequence which mediates cell attachment.	Glycine	104-107	secreted phosphoprotein 1	Bos taurus	42-53
7683462-0	1993	The cell attachment and spreading activity of vitronectin is dependent on the Arg-Gly-Asp sequence.	Glycine	82-85	vitronectin	Homo sapiens	46-57
7683462-2	1993	The cell attachment activity of vitronectin has been ascribed to an Arg-Gly-Asp (RGD) sequence near the amino terminus.	Glycine	72-75	vitronectin	Homo sapiens	32-43
8318987-3	1993	The PCR product from one of five patients revealed an alteration when mixed oligonucleotides representing variants of the second letter at codon 12 of this gene were used as 5" primers, and further experiments showed a mutation of GGT (Gly) to GAT (Asp) at codon 12.	Glycine	236-239	glycine-N-acyltransferase	Homo sapiens	244-247
29674746-6	2018	Mechanisms whereby tumours sustained HT under CD44-knockdown conditions include upregulation of PHGDH, PSAT1 and PSPH that drove glycolysis-dependent activation of serine/glycine-cleavage systems to provide one-methyl group for HT synthesis.	Glycine	171-178	phosphoserine phosphatase	Homo sapiens	113-117
29558951-5	2018	HM-3, an antitumor peptide including an Arg-Gly-Asp sequence, can specifically target integrin alphavbeta3 that is presented on some tumor cells.	Glycine	44-47	integrin subunit alpha V	Homo sapiens	86-106
8401606-5	1993	MFS18 mRNA is particularly associated with the vascular bundle in the glumes and encodes a polypeptide of 12 kDa, rich in glycine, proline and serine that has similarities with other plant structural proteins.	Glycine	122-129	MFS18 protein	Zea mays	0-5
8496014-1	1993	Bombesin (Bn, pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2) is one of the most potent peptides, possessing a variety of physiological and pharmacological functions.	Glycine	31-34	gastrin releasing peptide	Homo sapiens	0-8
8496014-1	1993	Bombesin (Bn, pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2) is one of the most potent peptides, possessing a variety of physiological and pharmacological functions.	Glycine	55-58	gastrin releasing peptide	Homo sapiens	0-8
8457570-9	1993	The small amounts of the Cys50--&gt;Gly and Cys74--&gt;Gly mutants found in the medium had specific activities that were much lower than that of the wild-type LCAT.	Glycine	36-39	lecithin-cholesterol acyltransferase	Homo sapiens	159-163
1465135-1	1992	The mammalian shc gene encodes two overlapping, widely expressed proteins of 46 and 52K, with a carboxy-terminal SH2 domain that binds activated growth factor receptors, and a more amino-terminal glycine/proline-rich region.	Glycine	196-203	SHC adaptor protein 1	Homo sapiens	14-17
8457570-9	1993	The small amounts of the Cys50--&gt;Gly and Cys74--&gt;Gly mutants found in the medium had specific activities that were much lower than that of the wild-type LCAT.	Glycine	55-58	lecithin-cholesterol acyltransferase	Homo sapiens	159-163
29440552-7	2018	Moreover, the IPSC-like responses of cells expressing alpha1A384Pbeta induced by repeated glycine pulses showed a stronger frequency-dependent reduction than those expressing alpha1WTbeta.	Glycine	90-97	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	54-61
8485574-4	1993	A base substitution was identified in the peripherin (RDS) gene and DNA sequencing revealed a G to A transition in codon 167 that substitutes aspartic acid for a highly conserved glycine.	Glycine	179-186	peripherin 2	Homo sapiens	54-57
8454474-0	1993	Hb Muskegon [beta 83(EF7)Gly--&gt;Arg]: a new variant found in a family from the U.S.	Glycine	25-28	FAM3 metabolism regulating signaling molecule D	Homo sapiens	21-24
7682659-1	1993	The actions of Pb2+ on NMDA channel currents of acutely dissociated hippocampal CA1- and CA3-neurones from adult rats activated by aspartate plus glycine (asp/gly) were examined.	Glycine	146-153	carbonic anhydrase 3	Rattus norvegicus	89-92
1464666-4	1992	Then, by screening Japanese diabetic patients using polymerase chain reaction--single strand conformation polymorphism (PCR-SSCP) and direct-sequencing strategies, we identified a missense mutation substituting arginine (AGG) for glycine (GGG) at position 261 in exon 7 of the glucokinase gene in a patient with early-onset non-insulin-dependent diabetes (NIDDM).	Glycine	230-237	glucokinase	Homo sapiens	277-288
1492919-2	1992	Poly (Val-Gly-Gly-Leu-Gly), a polypeptide mimicking the physico-chemical properties of the glycine-rich regions of elastin, has been synthesized and studied both in solution and in the aggregated state.	Glycine	91-98	elastin	Homo sapiens	115-122
29497022-7	2018	Comparison of the Kelch-domain structures of NS1-BP and its homologues showed that the Gly-Gly pair in beta-strand B and the hydrophobic Trp residue in beta-strand D are highly conserved, while the B-C loops in blades 2 and 6 are variable.	Glycine	87-90	influenza virus NS1A binding protein	Homo sapiens	45-51
8416952-1	1993	Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) is an essential enzyme that transfers myristate from CoA to the amino-terminal glycine residue of at least 12 cellular proteins.	Glycine	157-164	glycylpeptide N-tetradecanoyltransferase NMT1	Saccharomyces cerevisiae S288C	71-76
29497022-7	2018	Comparison of the Kelch-domain structures of NS1-BP and its homologues showed that the Gly-Gly pair in beta-strand B and the hydrophobic Trp residue in beta-strand D are highly conserved, while the B-C loops in blades 2 and 6 are variable.	Glycine	91-94	influenza virus NS1A binding protein	Homo sapiens	45-51
8381352-4	1993	Here we report that substitution of the palmitoylated cysteine by a glycine (Gly341 beta 2 AR) using site directed mutagenesis leads to a receptor being highly phosphorylated and largely uncoupled from Gs.	Glycine	68-75	adrenoceptor beta 2	Homo sapiens	84-93
29658513-5	2018	The presence of heterozygous Arg-Gly and Gln-Glu gives a better response to drug therapy than the presence of Gly-Gly and Glu-Glu genotypes at codons 16 and 27.ConclusionPolymorphism of beta2AR at codons 16 and 27 correlates with asthma severity and response to treatment in asthmatic children.	Glycine	33-36	adrenoceptor beta 2	Homo sapiens	186-193
8280370-4	1993	In contrast, nontumorigenic (immunogenic) variants (T-25-Adh and Rev-1) exhibited a Gly--&gt;Ser substitution at residue 242 of p53.	Glycine	84-87	REV1, DNA directed polymerase	Mus musculus	65-70
1429834-1	1992	The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in glycine and arginine (GAR domain).	Glycine	142-149	Hsp70 family ATPase SSB1	Saccharomyces cerevisiae S288C	34-38
1429834-1	1992	The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in glycine and arginine (GAR domain).	Glycine	142-149	Nsr1p	Saccharomyces cerevisiae S288C	50-54
21043846-5	1993	Like some other adhesive proteins such as fibrinogen, fibronectin, and von Willebrand factor, vitronectin contains the amino-acid sequence Arg-Gly-Asp (RGD) which enables binding to the platelet membrane glycoprotein complex IIb/IIIa (GPIIb/IIIa).	Glycine	143-146	vitronectin	Homo sapiens	94-105
29410408-1	2018	D-aminoacyl-tRNA deacylase (DTD), a bacterial/eukaryotic trans-editing factor, removes D-amino acids mischarged on tRNAs and achiral glycine mischarged on tRNAAla.	Glycine	133-140	solute carrier family 26 member 2	Homo sapiens	0-26
1283639-5	1992	They also show close quantitative resemblance to the channels of hippocampal CA1 and dentate gyrus cells and of cerebellar granule cells, except that the NR1-NR2A combination has a lower glycine sensitivity than the native channels.	Glycine	187-194	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	158-162
1383381-12	1992	In particular, conserved motifs in the alpha 1 helix and the conserved glycine at the base of the B pocket (position 45) provide a combination of features that is uniquely found in HLA-C molecules.	Glycine	71-78	major histocompatibility complex, class I, C	Homo sapiens	181-186
29167346-4	2018	Using forward and reverse genetics, we identified glycine zipper motifs within transmembrane helices 2 and 3 of NS4B that are critically involved in viral RNA replication.	Glycine	50-57	polyprotein;protein F	Hepatitis C virus genotype 1	112-116
1409579-1	1992	The mammalian shc gene encodes two overlapping proteins of 46 and 52 kDa, each with a C-terminal Src homology 2 (SH2) domain and an N-terminal glycine/proline-rich sequence, that induce malignant transformation when overexpressed in mouse fibroblasts.	Glycine	143-150	SHC adaptor protein 1	Homo sapiens	14-17
1390635-4	1992	Active matrilysin hydrolyzed the fluorescent substrate 2,4-dinitrophenyl-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 at the Gly-Leu bond with a maximum value for kcat/Km of 1.3 x 10(4) M-1 s-1 at the pH optimum of 6.5 and pKa values of 4.60 and 8.65.	Glycine	81-84	matrix metallopeptidase 7	Mus musculus	7-17
1388724-6	1992	DNA sequence analysis of beta ig-h3 indicated that it encoded a novel protein, beta IG-H3, of 683 amino acids, which contained an amino-terminal secretory sequence and a carboxy-terminal Arg-Gly-Asp (RGD) sequence that can serve as a ligand recognition site for several integrins.	Glycine	191-194	transforming growth factor beta induced	Homo sapiens	25-35
1388724-6	1992	DNA sequence analysis of beta ig-h3 indicated that it encoded a novel protein, beta IG-H3, of 683 amino acids, which contained an amino-terminal secretory sequence and a carboxy-terminal Arg-Gly-Asp (RGD) sequence that can serve as a ligand recognition site for several integrins.	Glycine	191-194	transforming growth factor beta induced	Homo sapiens	79-89
1384990-7	1992	Moreover, a single cysteine residue, tethered to the carboxy-terminal end of BPTI with a flexible linker of repeating Ser-Gly-Gly residues, is sufficient to assist in disulfide formation.	Glycine	122-125	spleen trypsin inhibitor I	Bos taurus	77-81
1384990-7	1992	Moreover, a single cysteine residue, tethered to the carboxy-terminal end of BPTI with a flexible linker of repeating Ser-Gly-Gly residues, is sufficient to assist in disulfide formation.	Glycine	126-129	spleen trypsin inhibitor I	Bos taurus	77-81
1445269-1	1992	By site-directed mutagenesis of a human complement factor C5a cDNA clone, we have designed a hybrid anaphylatoxin in which three amino acid residues in the C-terminal sequence of human C5a were exchanged to create the native C-terminal human C3a (hC3a) sequence Leu-Gly-Leu-Ala-Arg.	Glycine	266-269	complement C3	Homo sapiens	242-245
1447740-2	1992	Replacement of the N-terminal arginine by p-amidinophenylalanine or the Gly moiety by m-aminobenzoic acid led to compounds which are superior to the lead peptide with regard to activity and selectivity for GP IIb-IIIa vs the closely related vitronectin receptor alpha v beta 3.	Glycine	72-75	integrin subunit alpha 2b	Homo sapiens	206-212
1326552-10	1992	Cathepsin B also produced two fragments from a single cleavage at a Gly-Val bond only three amino acids C-terminal to the metalloproteinase cleavage site.	Glycine	68-71	cathepsin B	Homo sapiens	0-11
1326944-4	1992	Tetrapeptide RGDS (Arg-Gly-Asp-Ser), which blocks the interaction of ligands such as fibrinogen with platelet integrin alpha IIb beta 3 (GPIIb-IIIa), inhibited only the late-phase PtdIns(3,4)P2 accumulation that was associated with added Ca2+.	Glycine	23-26	integrin subunit alpha 2b	Homo sapiens	137-142
1623525-2	1992	The SHC cDNA is predicted to encode overlapping proteins of 46.8 and 51.7 kd that contain a single C-terminal SH2 domain, and an adjacent glycine/proline-rich motif with regions of homology with the alpha 1 chain of collagen, but no identifiable catalytic domain.	Glycine	138-145	SHC adaptor protein 1	Homo sapiens	4-7
1639922-5	1992	The synthetic peptides represented 1-3 multiple repeat units of the 5-residue sequence (Gly-His-His-Pro-His) found in the C-terminal of HRG.	Glycine	88-91	histidine rich glycoprotein	Homo sapiens	136-139
1339284-8	1992	The presence of a high concentration of glycine (22%), hydroxyproline and hydroxylysine in the amino acid composition of human SP-D indicated that it contained collagen-like structure.	Glycine	40-47	surfactant protein D	Homo sapiens	127-131
1598909-11	1992	The mutation changed the GGC codon for glycine-1143 to GAC for aspartate.	Glycine	39-46	gamma-glutamylcyclotransferase	Homo sapiens	25-28
1593215-3	1992	A guanine residue was replaced by an adenine residue converting Gly-292 (GGC) to Ser (AGC) in the last exon coding for the catalytic domain.	Glycine	64-67	gamma-glutamylcyclotransferase	Homo sapiens	73-76
1314130-6	1992	This mutation was a G to A transition in position 2 of codon 12, substituting aspartate (GAT) for glycine (GGT).	Glycine	98-105	glycine-N-acyltransferase	Homo sapiens	89-92
1541297-11	1992	In contrast, the H-protein (a specific protein component of the glycine-cleavage system) is known to be expressed primarily in leaves.	Glycine	64-71	myosin binding protein H	Homo sapiens	17-26
1542664-1	1992	Recent work has suggested that the thrombin-bound conformation of fibrinopeptide A exhibits a strand-turn-strand motif, with a beta-turn centered at residues Glu-11 and Gly-12.	Glycine	169-172	coagulation factor II, thrombin	Bos taurus	35-43
1371469-3	1992	Activation of these autoreactive cells requires the use of the vitronection receptor (VNR) as an accessory molecule which interacts with the Arg-Gly-Asp-Ser (RGDS) sequence of extracellular matrix (ECM) proteins.	Glycine	145-148	ral guanine nucleotide dissociation stimulator	Mus musculus	158-162
1576962-5	1992	The pum cDNA encodes a 157 x 10(3) M(r) protein which consists mainly of regions enriched in a single amino acid, usually glycine, alanine, glutamine or serine/threonine.	Glycine	122-129	pumilio	Drosophila melanogaster	4-7
1531511-5	1992	Cathepsin B/L-like activity was determined with Bz-Val-Lys-Lys-Arg-AFC, elastase-like activity with MeOSuc-Ala-Ala-Pro-Val-AFC, tryptase-like activity with Z-Ala-Ala-Lys-AFC, trypsin-like activity with Z-Gly-Gly-Arg-AFC and dipeptidyl peptidase (DPP) IV-like activity with Ala-Pro-AFC.	Glycine	204-207	cathepsin B	Homo sapiens	0-11
1531511-5	1992	Cathepsin B/L-like activity was determined with Bz-Val-Lys-Lys-Arg-AFC, elastase-like activity with MeOSuc-Ala-Ala-Pro-Val-AFC, tryptase-like activity with Z-Ala-Ala-Lys-AFC, trypsin-like activity with Z-Gly-Gly-Arg-AFC and dipeptidyl peptidase (DPP) IV-like activity with Ala-Pro-AFC.	Glycine	208-211	cathepsin B	Homo sapiens	0-11
1755838-1	1991	The effects of thyrotropin releasing hormone (TRH) and of TRH-like tripeptide pGlu-His-Gly-OH (colon mitosis inhibitor, CMI) on spontaneous proliferation of murine splenocytes were investigated in vitro.	Glycine	87-93	thyrotropin releasing hormone	Mus musculus	58-61
1722316-5	1991	The most common escape mutation was an amino acid change of asparagine (AAT) to aspartic acid (GAT) at position 280; an additional mutation was glycine (GGT) to aspartic acid (GAT) at position 282.	Glycine	144-151	glycine-N-acyltransferase	Homo sapiens	176-179
1722333-4	1991	The primary structure of hGal was determined by automatic Edman degradation to be Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu- Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr- Ser-COOH.	Glycine	82-85	galanin and GMAP prepropeptide	Homo sapiens	25-29
1839957-8	1991	Moreover, the attachment of IFN-gamma-treated Pam-T cells as well as non-treated cells to FN was blocked by the synthetic peptide Arg-Gly-Asp-Ser (RGDS), but not by the control peptide Arg-Gly-Glu-Ser.	Glycine	134-137	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	46-49
1839957-8	1991	Moreover, the attachment of IFN-gamma-treated Pam-T cells as well as non-treated cells to FN was blocked by the synthetic peptide Arg-Gly-Asp-Ser (RGDS), but not by the control peptide Arg-Gly-Glu-Ser.	Glycine	189-192	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	46-49
1717468-0	1991	Arginine-glycine-aspartic acid binding leading to molecular stabilization between integrin alpha v beta 3 and its ligand.	Glycine	9-16	integrin subunit alpha V	Homo sapiens	82-105
1684589-17	1991	A few cells in the GCL (0.5-1.5%) were glycine positive.	Glycine	39-46	germ cell-less 2, spermatogenesis associated	Homo sapiens	19-22
1896455-6	1991	An analogous peptide derivative from chimpanzee CD4 (containing a single Glu----Gly substitution at the position corresponding to CD4 residue 87) was considerably less active at inhibition of cell-cell fusion and stimulation of gp120 release, consistent with the known inhibitory effect of this substitution on the ability of membrane-associated CD4 to mediate cell fusion.	Glycine	80-83	CD4 molecule	Pan troglodytes	48-51
29167346-5	2018	Foerster resonance energy transfer analysis revealed the importance of the glycine zippers in NS4B homo- and heterotypic self-interactions.	Glycine	75-82	polyprotein;protein F	Hepatitis C virus genotype 1	94-98
1896455-6	1991	An analogous peptide derivative from chimpanzee CD4 (containing a single Glu----Gly substitution at the position corresponding to CD4 residue 87) was considerably less active at inhibition of cell-cell fusion and stimulation of gp120 release, consistent with the known inhibitory effect of this substitution on the ability of membrane-associated CD4 to mediate cell fusion.	Glycine	80-83	CD4 molecule	Pan troglodytes	130-133
1896455-6	1991	An analogous peptide derivative from chimpanzee CD4 (containing a single Glu----Gly substitution at the position corresponding to CD4 residue 87) was considerably less active at inhibition of cell-cell fusion and stimulation of gp120 release, consistent with the known inhibitory effect of this substitution on the ability of membrane-associated CD4 to mediate cell fusion.	Glycine	80-83	CD4 molecule	Pan troglodytes	130-133
29167346-7	2018	Notably, loss-of-function NS4B glycine zipper mutants prominently induced single-membrane vesicles with secondary invaginations that might represent an arrested intermediate state in double-membrane vesicle formation.	Glycine	31-38	polyprotein;protein F	Hepatitis C virus genotype 1	26-30
29167346-8	2018	These findings highlight a so-far-unknown role of glycine residues within the membrane integral core domain for NS4B self-interaction and functional as well as structural integrity of HCV replication organelles.IMPORTANCE Remodeling of the cellular endomembrane system leading to the establishment of replication organelles is a hallmark of positive-strand RNA viruses.	Glycine	50-57	polyprotein;protein F	Hepatitis C virus genotype 1	112-116
1353889-2	1992	mRNA synthesized from this clone (designated GLYT1) directs the expression of sodium- and chloride-dependent, high-affinity uptake of [3H]glycine by Xenopus oocytes.	Glycine	138-145	solute carrier family 6 member 9	Rattus norvegicus	45-50
1353889-4	1992	In situ hybridization reveals that GLYT1 is prominently expressed in the cervical spinal cord and brainstem, two regions of the central nervous system where glycine is a putative neurotransmitter.	Glycine	157-164	solute carrier family 6 member 9	Rattus norvegicus	35-40
29167346-11	2018	Here, we identify glycine zipper motifs within HCV NS4B transmembrane segments 2 and 3 that are crucial for the protein"s self-interaction.	Glycine	18-25	polyprotein;protein F	Hepatitis C virus genotype 1	51-55
1889089-2	1991	In un mice, a point mutation leading to a Gly-Ser exchange in a conserved part of the paired domain of Pax-1 is present.	Glycine	42-45	paired box 1	Mus musculus	103-108
1889089-5	1991	Comparison of the DNA-binding properties of wild-type and un Pax-1 proteins demonstrates that the Gly-Ser replacement at position 15 within the paired domain dramatically decreases the DNA-binding affinity of the un Pax-1 protein and alters its DNA-binding specificity.	Glycine	98-101	paired box 1	Mus musculus	61-66
1889089-5	1991	Comparison of the DNA-binding properties of wild-type and un Pax-1 proteins demonstrates that the Gly-Ser replacement at position 15 within the paired domain dramatically decreases the DNA-binding affinity of the un Pax-1 protein and alters its DNA-binding specificity.	Glycine	98-101	paired box 1	Mus musculus	216-221
29167346-12	2018	Moreover, glycine residues within NS4B transmembrane helices critically contribute to the biogenesis of functional replication organelles and, thus, efficient viral RNA replication.	Glycine	10-17	polyprotein;protein F	Hepatitis C virus genotype 1	34-38
29167346-13	2018	These results reveal how glycine zipper motifs in NS4B contribute to structural and functional integrity of the HCV replication organelles and, thus, viral RNA replication.	Glycine	25-32	polyprotein;protein F	Hepatitis C virus genotype 1	50-54
29220410-6	2017	Bioinformatic prediction and verification of the predicted site by site-directed mutagenesis experiments determined that the NFAT5 protein was cleaved by CVB3 protease 2A at Glycine 503.	Glycine	174-181	nuclear factor of activated T cells 5	Mus musculus	125-130
1958054-3	1991	The active form is generated upon proteolytic cleavage of the N-terminal prophospholipase A2 activation peptide (PLAP), with the sequence Asp-Ser-Gly-Ile-Ser-Pro-Arg (DSGISPR).	Glycine	146-149	phospholipase A2 activating protein	Homo sapiens	73-111
1958054-3	1991	The active form is generated upon proteolytic cleavage of the N-terminal prophospholipase A2 activation peptide (PLAP), with the sequence Asp-Ser-Gly-Ile-Ser-Pro-Arg (DSGISPR).	Glycine	146-149	phospholipase A2 activating protein	Homo sapiens	113-117
1714600-7	1991	Since other DR4 subtypes with substitutions at positions 70-74 also fail to present this peptide, and glycine residues can be uniquely flexible, we suggest that this replacement at position 86 acts locally or at a distance by altering the conformation of the peptide-binding cleft.	Glycine	102-109	major histocompatibility complex, class II, DR beta 4	Homo sapiens	12-15
1376965-6	1992	It is interesting that such glycine substitutions inside the COL1A1 or COL1A2 genes have been associated with many cases of osteogenesis imperfecta.	Glycine	28-35	collagen type I alpha 1 chain	Homo sapiens	61-67
28732179-6	2017	However, HYD-1 (Lys-Ile-Lys-Met-Val-Ile-Ser-Trp-Lys-Gly), an integrin antagonist, inhibited the KGF-enhanced epithelial adhesion and rete peg elongation.	Glycine	52-55	msh homeobox 1	Homo sapiens	9-14
1429036-5	1992	In contrast, 16% of patients compared with 38% of controls carry DQB1 alleles encoding tyrosine at the same residue, and 22% of patients versus 44% of controls carry DQB1 alleles encoding glycine at residue 26.	Glycine	188-195	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	166-170
1314561-9	1992	The chondroitin sulphate-attachment site was assigned to Ser-492 as this residue is conserved in mouse and bovine thrombomodulin and lies within a sequence Ser-Gly-Ser-492-Gly-Glu-Pro, which has strong similarity to chondroitin sulphate attachment sites in other proteoglycans.	Glycine	172-175	thrombomodulin	Bos taurus	114-128
2035536-0	1991	A single base mutation in type I procollagen (COL1A1) that converts glycine alpha 1-541 to aspartate in a lethal variant of osteogenesis imperfecta: detection of the mutation with a carbodiimide reaction of DNA heteroduplexes and direct sequencing of products of the PCR.	Glycine	68-75	collagen type I alpha 1 chain	Homo sapiens	46-52
2035536-5	1991	Subsequent amplification of the cDNA by the PCR and nucleotide sequencing revealed a single-base mutation that substituted an aspartate codon for glycine at position alpha 1-541 in the COL1A1 gene.	Glycine	146-153	collagen type I alpha 1 chain	Homo sapiens	185-191
29226620-7	2017	Glycine conjugate of OCA increased mRNA levels of FXR target genes in Caco-2 cells, FGF-19, SHP, OSTalpha/beta, and IBABP, but not ASBT, in a concentration-dependent manner, while glycine conjugate of UDCA had no effect on the expression of these genes.	Glycine	0-7	solute carrier family 51 subunit alpha	Homo sapiens	97-110
1719444-6	1991	The rotational response was attenuated by prior administration of an NK-2 antagonist (cyclo (Gln, Trp, Phe, Gly, Leu, Met)] L-659877]) into the nigra.	Glycine	108-111	tachykinin receptor 2	Homo sapiens	69-73
29226620-7	2017	Glycine conjugate of OCA increased mRNA levels of FXR target genes in Caco-2 cells, FGF-19, SHP, OSTalpha/beta, and IBABP, but not ASBT, in a concentration-dependent manner, while glycine conjugate of UDCA had no effect on the expression of these genes.	Glycine	0-7	fatty acid binding protein 6	Homo sapiens	116-121
29096248-3	2017	We detected a novel RGD (Arg-Gly-Asp)-containing peptide derived from the C-terminal portion of fibrinogen in the sera of metastatic patients that appeared to control the EMT (epithelial-mesenchymal transition) of cancer cells, in a process associated with miR-199a-3p.	Glycine	29-32	microRNA 199a-2	Homo sapiens	257-268
2026597-6	1991	Trypsin digestion of [14C]BrAnd-inactivated 3 alpha-HSD followed by peptide mapping led to the purification of a single radiolabeled peptide (3A1) which gave the following sequence: H2N-Ser-Ile-Gly-Val-Ser-Asn-Phe-Asn-X-Arg-CO2H.	Glycine	194-197	aldo-keto reductase family 1, member C14	Rattus norvegicus	44-55
1556182-4	1992	In fact, the presence of a DQB1 allele having a polar glycine or tyrosine at position 26 of the DQB1 first domain versus a hydrophobic leucine accounted for 100% of ACA positive Caucasian systemic sclerosis patients compared to 69% of the ACA negative SS patients (P = 0.0008) and 71% of Caucasian controls (P = 0.0003) as well as all 7 ACA patients of non-Caucasian background.	Glycine	54-61	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	27-31
1556182-4	1992	In fact, the presence of a DQB1 allele having a polar glycine or tyrosine at position 26 of the DQB1 first domain versus a hydrophobic leucine accounted for 100% of ACA positive Caucasian systemic sclerosis patients compared to 69% of the ACA negative SS patients (P = 0.0008) and 71% of Caucasian controls (P = 0.0003) as well as all 7 ACA patients of non-Caucasian background.	Glycine	54-61	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	96-100
28919253-1	2017	We have previously shown that application of beta-amyloid peptide 1-42 (Abeta) at picomolar/nanomolar concentrations caused a decrease in the peak amplitude and acceleration of desensitization of the glycine-activated chloride current (IGly) in hippocampal pyramidal neurons (Bukanova et al., 2016).	Glycine	200-207	amyloid beta precursor protein	Rattus norvegicus	72-77
1311930-3	1992	The latter two residues provide a unique hydroxylamine-sensitive link between [Met1]-pGH(1-46) and the N-terminal Gly of IGF-I.	Glycine	114-117	IGFI	Bos taurus	121-126
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	vitronectin	Homo sapiens	292-303
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	vitronectin	Homo sapiens	305-307
1600374-1	1992	This paper describes a method for the direct gas/liquid chromatographic (GC) analysis of 46 glycine-conjugated bile acids, which differ from one another in the number, position and configuration of the hydroxyl groups at positions C-2, C-3, C-4, C-6, C-7 and/or C-12.	Glycine	92-99	complement C3	Homo sapiens	236-239
1708943-0	1991	Novel effect of cyclicization of the Arg-Gly-Asp-containing peptide on vitronectin binding to platelets.	Glycine	41-44	vitronectin	Homo sapiens	71-82
2002350-1	1991	The sulphated octapeptide of cholecystokinin (CCK-8S) was found to cause a dose-dependent increase in the basal release of aspartate, glycine, and gamma-aminobutyric acid from the striatum and the ventromedial nucleus of the hypothalamus (VMH).	Glycine	134-141	cholecystokinin	Rattus norvegicus	29-44
29053416-1	2017	Integrin alphavbeta3 is a molecular marker for the estimation of tumor angiogenesis and is an imaging target for radiolabeled Arg-Gly-Asp (RGD) peptides.	Glycine	130-133	integrin subunit alpha V	Homo sapiens	0-20
2005390-4	1991	In initial experiments, C57BL/6 mice were immunized with a synthetic peptide corresponding to residues 5 through 16 of p21 containing the transforming substitution of arginine for normal glycine at residue 12.	Glycine	187-194	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	119-122
1600374-1	1992	This paper describes a method for the direct gas/liquid chromatographic (GC) analysis of 46 glycine-conjugated bile acids, which differ from one another in the number, position and configuration of the hydroxyl groups at positions C-2, C-3, C-4, C-6, C-7 and/or C-12.	Glycine	92-99	complement C7	Homo sapiens	251-254
1596690-2	1992	Milacemide is a glycine prodrug which is both an inhibitor and a substrate for monoamine oxidase-type B (MAO-B) and also an inhibitor of MAO-type A (MAO-A).	Glycine	16-23	monoamine oxidase B	Rattus norvegicus	79-103
1996137-5	1991	We have identified single nucleotide alterations that substitute glutamic acid for glycine in the triple-helical Gly-X-Y repeat region of the alpha 1(IV) collagen in three emb-9 mutant strains.	Glycine	83-90	Collagen alpha-1(IV) chain	Caenorhabditis elegans	172-177
28916707-3	2017	Here we show pharyngeal gland cell expression of PQN-75, a unique protein containing an N-terminal signal peptide, nucleoporin (Nup)-like phenylalanine/glycine (FG) repeats, and an extensive polyproline repeat domain with similarities to human basic salivary proline-rich pre-protein PRB2.	Glycine	152-159	Prion-like-(Q/N-rich)-domain-bearing protein	Caenorhabditis elegans	49-55
1996137-5	1991	We have identified single nucleotide alterations that substitute glutamic acid for glycine in the triple-helical Gly-X-Y repeat region of the alpha 1(IV) collagen in three emb-9 mutant strains.	Glycine	113-116	Collagen alpha-1(IV) chain	Caenorhabditis elegans	172-177
1596690-2	1992	Milacemide is a glycine prodrug which is both an inhibitor and a substrate for monoamine oxidase-type B (MAO-B) and also an inhibitor of MAO-type A (MAO-A).	Glycine	16-23	monoamine oxidase B	Rattus norvegicus	105-110
28916707-3	2017	Here we show pharyngeal gland cell expression of PQN-75, a unique protein containing an N-terminal signal peptide, nucleoporin (Nup)-like phenylalanine/glycine (FG) repeats, and an extensive polyproline repeat domain with similarities to human basic salivary proline-rich pre-protein PRB2.	Glycine	152-159	RANBP2 like and GRIP domain containing 2	Homo sapiens	128-131
28955208-1	2017	The alpha9 and alpha10 nicotinic acetylcholine receptor (nAChR) subunits are likely to be the evolutionary precursors to the entire cys-loop superfamily of ligand-gated ion channels, which includes acetylcholine, GABA, glycine and serotonin ionotropic receptors.	Glycine	219-226	integrin alpha 9	Mus musculus	4-22
1591047-5	1992	A single Ki-ras mutation (codon 12, gly- greater than val) was detected in a patient with a pT2N2M1 tumour.	Glycine	36-39	KRAS proto-oncogene, GTPase	Homo sapiens	9-15
1671321-0	1991	The glycine cleavage system: structure of a cDNA encoding human H-protein, and partial characterization of its gene in patients with hyperglycinemias.	Glycine	4-11	myosin binding protein H	Homo sapiens	64-73
28824188-5	2017	A novel mutation (173 A&gt;G) in exon 4 with a predicted amino acid change of 58 Asp&gt;Gly was also found in a Kinh newborn girl and her father, and it was designated as G6PD Ho Chi Minh.	Glycine	88-91	glucose-6-phosphate dehydrogenase	Homo sapiens	171-175
2032737-5	1991	These G----A mutations result in the replacement of the normal glycine in the 12th position of the ras p21 protein by a glutamic acid residue.	Glycine	63-70	KRAS proto-oncogene, GTPase	Rattus norvegicus	103-106
1327034-8	1992	Colon cancer is mainly associated with mutations leading to substitution of the normal glycine at amino acid position 12 of K-ras by either valine or aspartic acid, and mutations in N-ras are not exceptional.	Glycine	87-94	KRAS proto-oncogene, GTPase	Homo sapiens	124-129
28572117-6	2017	In contrast, the dynactin complex counteracts dynein and stabilizes microtubules through a mechanism involving the shoulder subcomplex and the cytoskeletal-associated protein glycine-rich domain of Nip100/p150glued Our results support a model in which dynein destabilizes its microtubule substrate by using its motility to deplete dynactin from the plus end.	Glycine	175-182	Nip100p	Saccharomyces cerevisiae S288C	198-204
1729723-2	1992	This enzyme, which has an apparent molecular mass of 100 kDa, performs a selective cleavage at the Xaa-Phe, Xaa-Leu, or Xaa-Ile bond (Xaa = Ser, Phe, Tyr, His, or Gly) of a number of peptide hormones, including atrial natriuretic factor, substance P, angiotensin II, bradykinin, somatostatin, neuromedins B and C, and litorin.	Glycine	163-166	tachykinin precursor 1 S homeolog	Xenopus laevis	238-249
1943691-2	1991	For the study on molecular genetics of non-ketotic hyperglycinemia, we have isolated several cDNA clones, each encoding human glycine decarboxylase of H-protein, two of the four component enzymes of the glycine cleavage system.	Glycine	56-63	myosin binding protein H	Homo sapiens	151-160
28204846-3	2017	EB1 autonomously binds an extended tubulin-GTP/GDP-Pi structure at growing microtubule ends and acts as a molecular scaffold that recruits a large number of regulatory +TIPs through interaction with CAP-Gly or SxIP motifs.	Glycine	203-206	microtubule associated protein RP/EB family member 1	Homo sapiens	0-3
1846292-9	1991	Both IGF I receptor dimers and tetramers exhibit similar kinase activities using the synthetic substrate Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly, indicating that the failure to detect autophosphorylation of the IGF I receptor dimers does not result from inactivation of the kinase by DTT treatment.	Glycine	153-156	insulin like growth factor 1 receptor	Homo sapiens	5-19
1846292-9	1991	Both IGF I receptor dimers and tetramers exhibit similar kinase activities using the synthetic substrate Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly, indicating that the failure to detect autophosphorylation of the IGF I receptor dimers does not result from inactivation of the kinase by DTT treatment.	Glycine	153-156	insulin like growth factor 1 receptor	Homo sapiens	223-237
1985904-2	1991	As is the case with many other peptide hormones of the brain and intestine, the formation of biologically active gastrin from a glycine-extended processing intermediate occurs via the action of a peptidylglycyl alpha-amidating monooxygenase (PAM).	Glycine	128-135	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	196-240
1985904-2	1991	As is the case with many other peptide hormones of the brain and intestine, the formation of biologically active gastrin from a glycine-extended processing intermediate occurs via the action of a peptidylglycyl alpha-amidating monooxygenase (PAM).	Glycine	128-135	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	242-245
1756315-1	1991	Using antisera (alpha-R and alpha-C7Ag) directed against the conserved Gly-Gly-Met-Pro-epitope of the hsp70 family, a single antigen was identified in the human Babesia divergens Rouen 1987 isolate by Western immunoblotting and immunoprecipitation experiments.	Glycine	71-74	heat shock protein family A (Hsp70) member 4	Homo sapiens	102-107
1962623-3	1991	The predominant mutation was from glycine (GGT) to aspartic acid (GAT).	Glycine	34-41	glycine-N-acyltransferase	Homo sapiens	66-69
1747941-6	1991	This mutation codes for glutamate instead of glycine as the 12th amino acid of the ras p21 protein.	Glycine	45-52	KRAS proto-oncogene, GTPase	Rattus norvegicus	87-90
28514686-3	2017	Based on targeted glycine substitutions in the Env fusion machinery, we defined a general approach that disfavors helical transitions leading to post-fusion conformations, thereby favoring the pre-fusion state.	Glycine	18-25	endogenous retrovirus group K member 20	Homo sapiens	47-50
2085103-5	1990	The amino acid levels did not differ significantly when the feeding groups were compared week by week, but the glycine/valine ratio was higher (p less than 0.05) in the HMP group after three weeks of fortification.	Glycine	111-118	inner membrane mitochondrial protein	Homo sapiens	169-172
28246168-0	2017	Role of glycine 221 in catalytic activity of hyaluronan-binding protein 2.	Glycine	8-15	hyaluronan binding protein 2	Homo sapiens	45-73
2085103-8	1990	Glycine in the HMP group peaked after two weeks (p less than 0.02), and valine in the CMP group increased (p less than 0.02) after one week on the feeding regimen.	Glycine	0-7	inner membrane mitochondrial protein	Homo sapiens	15-18
2260635-10	1990	The results of these experiments show that attachment and spreading of bovine aortic endothelial and smooth muscle cells depend primarily on the presence of the Arg-Gly-Asp-Ser (RGDS) sequence in the recombinant fibronectin proteins.	Glycine	165-168	ral guanine nucleotide dissociation stimulator	Mus musculus	178-182
1659809-5	1991	The following mutants exhibited a decreased ability to inhibit PDE alpha/beta: Tyr84----Gly; Arg24----Gly; and Arg33----Pro.	Glycine	88-91	phosphodiesterase 6A	Homo sapiens	63-72
28246168-4	2017	Here, we used G221E, G221A, and G221S mutants to assess the role of Gly-221 in HABP2 catalysis.	Glycine	68-71	hyaluronan binding protein 2	Homo sapiens	79-84
28387240-2	2017	The GluD2 receptor is a puzzling member of the iGluR family: It is involved in synaptic plasticity, plays a role in human diseases, e.g. ataxia, binds glycine and D-serine with low affinity, yet no ligand has been discovered so far that can activate its ion channel.	Glycine	151-158	glutamate dehydrogenase 2	Homo sapiens	4-9
1657158-1	1991	Twelve amino acid substitutions of varying size and hydrophobicity were constructed at Val 143 in human carbonic anhydrase II (including Gly, Ser, Cys, Asn, Asp, Leu, Ile, His, Phe and Tyr) to examine the catalytic roles of the hydrophobic pocket in the active site of this enzyme.	Glycine	137-140	carbonic anhydrase 2	Homo sapiens	104-125
1722966-1	1991	P62 is a synthetic peptide which corresponds to the glycine/alanine repeat sequence of Epstein-Barr virus nuclear antigen-1.	Glycine	52-59	nucleoporin 62	Homo sapiens	0-3
2201686-2	1990	The requirement of an L-aspartate in the P-1 position was confirmed together with the need for a small hydrophobic residue in the P-1" position (Gly or Ala).	Glycine	145-148	crystallin gamma F, pseudogene	Homo sapiens	130-133
28188227-9	2017	The presence of Erap1 increased the frequency of C-terminal Lys and Arg, of Glu and Asp at intermediate residues, and of N-terminal Gly.	Glycine	132-135	endoplasmic reticulum aminopeptidase 1	Rattus norvegicus	16-21
2123729-5	1990	At a concentration of 0.01 mM the net movement for phenylalanine, serine, aspartate and glycine was from blood to CSF.	Glycine	88-95	granulocyte-macrophage colony-stimulating factor	Ovis aries	114-117
2217833-0	1990	Electrophilic levuglandin E2-protein adducts bind glycine: a model for protein crosslinking.	Glycine	50-57	ubiquitin conjugating enzyme E2 B	Homo sapiens	26-36
1718779-2	1991	Cyclic Arg-Gly-Asp-Phe-Val peptides with either D-Phe or D-Val residues were 20- to more than 100-fold better inhibitors of cell adhesion to vitronectin and/or laminin fragment P1 when compared to a linear variant or Gly-Arg-Gly-Asp-Ser.	Glycine	11-14	vitronectin	Homo sapiens	141-152
1718779-2	1991	Cyclic Arg-Gly-Asp-Phe-Val peptides with either D-Phe or D-Val residues were 20- to more than 100-fold better inhibitors of cell adhesion to vitronectin and/or laminin fragment P1 when compared to a linear variant or Gly-Arg-Gly-Asp-Ser.	Glycine	217-220	vitronectin	Homo sapiens	141-152
28057537-3	2017	Na+-K+-2Cl- co-transporter 1 (NKCC1) and K+-Cl- co-transporter 2 (KCC2) generally dictate the tone of GABA/glycine inhibition by regulating intracellular chloride concentrations.	Glycine	107-114	solute carrier family 12 member 5	Homo sapiens	41-64
1778986-1	1991	Three DNA constructs, pETB-40, 41, and 42, encoding human big endothelin-1 (ET-1) preceded by the specific recognition sequence (Ile-Glu-Gly-Arg) for the activated blood coagulation factor Xa (FXa), fused in frame to the N-terminal portion of beta Gal, were expressed in Escherichia coli.	Glycine	137-140	coagulation factor X	Homo sapiens	182-191
28057537-3	2017	Na+-K+-2Cl- co-transporter 1 (NKCC1) and K+-Cl- co-transporter 2 (KCC2) generally dictate the tone of GABA/glycine inhibition by regulating intracellular chloride concentrations.	Glycine	107-114	solute carrier family 12 member 5	Homo sapiens	66-70
2358462-5	1990	However, M-ASGP-BP was characteristic in having a shorter cytoplasmic tail, and an inserted segment of 24 amino acids containing an Arg-Gly-Asp sequence between the membrane-spanning region and carbohydrate recognition domain.	Glycine	136-139	C-type lectin domain containing 10A	Rattus norvegicus	9-18
28164892-0	2017	Novel glycine substitution G2037R of COL7A1 in a Chinese boy with pretibial epidermolysis bullosa treated with oral olopatadine hydrochloride and topical Vitamin E.	Glycine	6-13	collagen type VII alpha 1 chain	Homo sapiens	37-43
2191151-3	1990	Determination of the amino-terminal sequence revealed glycine as the first amino acid in the Nef protein, indicating removal of the initiator methionine during expression in E. coli.	Glycine	54-61	Nef	Human immunodeficiency virus 1	93-96
1821759-1	1991	In French bean, the glycine-rich cell wall protein GRP 1.8 is specifically synthesized in the vascular tissue.	Glycine	20-27	glycine-rich RNA-binding protein-like	Nicotiana tabacum	51-56
28849491-2	2017	Ala, Gln, Gly, Lys, Val and taurine (Tau) are the most abundant free AAs in mammals, and some of these react with hypochlorite (HOCl/OCl-) produced by myeloperoxidase in activated phagocytes to form N-chloroamino acids (NCAA).	Glycine	10-13	myeloperoxidase	Mus musculus	151-166
1898363-4	1991	Both forms catalysed the rapid fixation of [14C]bicarbonate to the carboxy group atom of glycine during the exchange reaction, whereas the reversible exchange of electrons between NADH and lipoamide bound to the H-protein in the presence of 5,5"-dithiobis-(2-nitrobenzoic acid) was seen only with the form eluted at 350 mM-KCl.	Glycine	89-96	myosin binding protein H	Homo sapiens	212-221
1898363-5	1991	During the early steps of H-protein isolation, when P- and H-protein react together in the presence of glycine, the methylamine intermediate bound to the lipoamide of the H-protein accumulates in the medium at the expense of oxidized H-protein.	Glycine	103-110	myosin binding protein H	Homo sapiens	26-35
1910042-2	1991	Eleven amino acid substitutions at Val-121 of human carbonic anhydrase II including Gly, Ala, Ser, Leu, Ile, Lys, and Arg, were constructed by site-directed mutagenesis.	Glycine	84-87	carbonic anhydrase 2	Homo sapiens	52-73
1908084-8	1991	DNA sequence analysis showed that the mutations are located in four regions of VirA: transmembrane domain one, the active site, a glycine-rich region with homology to ATP-binding sites, and a region at the C terminus that has homology to the N terminus of VirG.	Glycine	130-137	two-component VirA-like sensor kinase	Agrobacterium tumefaciens	79-83
1907272-1	1991	The Arg-Gly-Asp (RGD)-binding domain of GPIIb-IIIa has been localized in a fragment of the GPIIIa subunit that includes the sequence between amino acids 109 and 171.	Glycine	8-11	integrin subunit alpha 2b	Homo sapiens	40-45
1655111-4	1991	The glycine site agonist D-serine 10(-4) M potentiated basal and NMDA-stimulated alpha-MSH release whilst the antagonist, 7-chlorokynurenic acid 10(-4) M, reduced NMDA-stimulated release, an effect which was partially reversed by 10(-4) M D-serine.	Glycine	4-11	proopiomelanocortin	Rattus norvegicus	81-90
1659747-9	1991	In the third experiment the RGDS peptide (ARG-GLY-ASP-SER), a blocker of GPIIb/IIIa platelet receptor dose dependently inhibited platelet aggregation by 93 +/- 17%.	Glycine	46-49	integrin subunit alpha 2b	Homo sapiens	73-78
1939467-3	1991	The separation of unconjugated and glycine- and taurine-conjugated bile acids with a C-3 oxo group has been carried out by high-performance liquid chromatography on a reversed-phase column.	Glycine	35-42	complement C3	Homo sapiens	85-88
1943708-1	1991	Oligonucleotide-directed mutagenesis of ctxB was used to produce mutants of cholera toxin B subunit (CT-B) altered at residues Cys-9, Gly-33, Lys-34, Arg-35, Cys-86 and Trp-88.	Glycine	134-137	phosphate cytidylyltransferase 1B, choline	Homo sapiens	76-99
1943708-1	1991	Oligonucleotide-directed mutagenesis of ctxB was used to produce mutants of cholera toxin B subunit (CT-B) altered at residues Cys-9, Gly-33, Lys-34, Arg-35, Cys-86 and Trp-88.	Glycine	134-137	phosphate cytidylyltransferase 1B, choline	Homo sapiens	101-105
1829526-3	1991	Its binding to FN was inhibited by anti-FN antibody or a mixture of synthetic peptides corresponding to two different sites of FN, termed the V10 sequence and the RGDS (Arg-Gly-Asp-Ser) sequence, which interact, respectively, with the VLA-4 and VLA-5 FN receptors expressed on T-lineage cells.	Glycine	173-176	ral guanine nucleotide dissociation stimulator	Mus musculus	163-167
2025283-0	1991	The primary structure of human H-protein of the glycine cleavage system deduced by cDNA cloning.	Glycine	48-55	myosin binding protein H	Homo sapiens	31-40
2025283-1	1991	A full-length cDNA encoding the human H-protein of the glycine cleavage system has been isolated from a lambda gt11 human fetal liver cDNA library.	Glycine	55-62	myosin binding protein H	Homo sapiens	38-47
2026264-4	1991	The P1" subsite of P79 is isosteric with the glycine residue of the natural thrombin substrate fibrinogen, but is proteolytically stable due to the incorporation of a ketomethylene pseudopeptide bond.	Glycine	45-52	coagulation factor II, thrombin	Bos taurus	76-84
2009266-4	1991	However, the site of thrombin-catalyzed cleavage, which in other species consists of an Arg-Gly peptide bond, is instead an Arg-Ala bond in the chicken beta chain.	Glycine	92-95	coagulation factor II, thrombin	Gallus gallus	21-29
1706724-6	1991	Interestingly, the NSR1 protein has two RNA recognition motifs, as well as an acidic NH2 terminus containing a series of serine clusters, and a basic COOH terminus containing arg-gly repeats.	Glycine	10-13	Nsr1p	Saccharomyces cerevisiae S288C	19-23
1705013-4	1991	The N-terminal part of Tst-1 protein is highly glycine- and alanine-rich, a structural feature shared by the helix-loop-helix protein TFEB.	Glycine	47-54	TST1	Homo sapiens	23-28
1804982-2	1991	Intracellular recordings employing current and voltage clamp techniques were used to study the effects of glycine on rat CA3 hippocampal neurones during the first 3 weeks of postnatal (P) life.	Glycine	106-113	carbonic anhydrase 3	Rattus norvegicus	121-124
2014004-4	1991	SHMT catalyses the biosynthesis of glycine from serine and the transfer of a one-carbon unit to tetrahydrofolate.	Glycine	35-42	serine hydroxymethyltransferase	Glycine max	0-4
2126014-7	1990	Like both alpha- and beta-adaptins, gamma-adaptin has a proline and glycine-rich hinge region, dividing it into NH2- and COOH-terminal domains.	Glycine	68-75	adaptor protein complex AP-1, gamma 1 subunit	Mus musculus	10-49
2277087-14	1990	We hypothesize that IAP may play a role in signal transduction for enhanced phagocytosis by Arg-Gly-Asp ligands.	Glycine	96-99	CD47 molecule	Homo sapiens	20-23
1699942-3	1990	The cDNA encodes a proline-, serine-, and glycine-rich nuclear protein designated Nup475 of 319 amino acids that contains two tandemly repeated cysteine- and histidine-containing sequences (CX8CX5CX3H) suggestive of a novel heavy metal-binding domain.	Glycine	42-49	zinc finger protein 36	Mus musculus	82-88
2271648-3	1990	PSG9 and PSG10 are representatives of two distinct classes of PSG protein that have N-termini with or without the Arg-Gly-Asp motif implicated in adhesion.	Glycine	118-121	pregnancy specific beta-1-glycoprotein 10, pseudogene	Homo sapiens	9-14
2248952-0	1990	Glycine to alanine substitutions in helices of glyceraldehyde-3-phosphate dehydrogenase: effects on stability.	Glycine	0-7	glyceraldehyde-3-phosphate dehydrogenase	Gallus gallus	47-87
2205309-6	1990	Eighty percent of the mutations involved substitution of aspartic acid for glycine (G----A) in the 12th or 13th codons of N-ras or K-ras.	Glycine	75-82	NRAS proto-oncogene, GTPase	Homo sapiens	122-127
2205309-6	1990	Eighty percent of the mutations involved substitution of aspartic acid for glycine (G----A) in the 12th or 13th codons of N-ras or K-ras.	Glycine	75-82	KRAS proto-oncogene, GTPase	Homo sapiens	131-136
2163679-1	1990	Various gastrin analogues and CCK-8 (Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2) are hydrolyzed in vitro by angiotensin-converting enzyme (ACE), the main and initial cleavage occurring at the Met-Asp (or Leu-Asp) bond, releasing the C-terminal dipeptide amide Asp-Phe-NH2.	Glycine	55-58	gastrin	Rattus norvegicus	8-15
2372538-1	1990	Peptidylglycine alpha-amidating monooxygenase (PAM, EC 1.14.17.3) catalyzes the formation of alpha-amidated peptides from their glycine-extended precursors, thus playing a key role in the processing of peptide neurohormones.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	47-50
2159243-1	1990	Formation of biologically active amidated gastrin from glycine-extended progastrin processing intermediates (G-Gly) is achieved via the action of peptidyl-glycyl alpha-amidating monooxygenase.	Glycine	55-62	gastrin	Rattus norvegicus	42-49
2343164-1	1990	The formation of biologically active gastrin from glycine-extended processing intermediates occurs via the action of a peptide alpha-amidating enzyme.	Glycine	50-57	gastrin	Rattus norvegicus	37-44
2331513-1	1990	The peptide N-Boc-L-Pro-dehydro-Phe-L-Gly-OH was synthesized by the usual workup procedure and finally coupling the N-Boc-L-Pro-dehydro-Phe to glycine.	Glycine	143-150	BOC cell adhesion associated, oncogene regulated	Homo sapiens	14-17
2331513-1	1990	The peptide N-Boc-L-Pro-dehydro-Phe-L-Gly-OH was synthesized by the usual workup procedure and finally coupling the N-Boc-L-Pro-dehydro-Phe to glycine.	Glycine	143-150	BOC cell adhesion associated, oncogene regulated	Homo sapiens	118-121
2295596-2	1990	For this purpose, the plasmid pBR322 was mutated so that the codon (AGC) of the active site Ser-68 in the beta-lactamase gene was changed to the glycine codon GGC to inactivate the encoded enzyme.	Glycine	145-152	gamma-glutamylcyclotransferase	Homo sapiens	159-162
2283296-1	1990	Hb Iowa with a Gly----Ala mutation at position beta 119(GH2) was observed in a Black infant and her mother.	Glycine	15-18	growth hormone 2	Homo sapiens	56-59
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	synaptophysin	Homo sapiens	64-77
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	synaptophysin	Homo sapiens	64-77
33806675-0	2021	SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine-Glycine-One-Carbon Pathways in Cancer.	Glycine	56-63	solute carrier family 6 member 14	Homo sapiens	0-7
33806675-9	2021	SLC6A14 and SLC38A5 are the two transporters that are upregulated in a variety of cancers to mediate the influx of glutamine, serine, glycine, and methionine into cancer cells.	Glycine	134-141	solute carrier family 6 member 14	Homo sapiens	0-7
10219997-7	1999	These data strongly suggest that the GSH2 gene encodes a bifunctional enzyme that is able to catalyse both the synthesis of GSH by adding glycine to the dipeptide (gammaGlu-Cys) and the synthesis of phytochelatins.	Glycine	138-145	glutathione synthetase 2	Arabidopsis thaliana	37-41
8269939-5	1993	These results, together with the fact that big ET-2 and big ET-3 show heterogeneity in the big ET-1 residues His27, Val28, Val29 and Gly34, suggest that the His27-Val-Val-Pro-Tyr-Gly-Leu-Gly34 sequence in the carboxy-terminal region of big ET-1 plays the most important role in selective conversion by endothelin converting enzyme.	Glycine	133-136	endothelin 1	Bos taurus	95-99
8269939-5	1993	These results, together with the fact that big ET-2 and big ET-3 show heterogeneity in the big ET-1 residues His27, Val28, Val29 and Gly34, suggest that the His27-Val-Val-Pro-Tyr-Gly-Leu-Gly34 sequence in the carboxy-terminal region of big ET-1 plays the most important role in selective conversion by endothelin converting enzyme.	Glycine	133-136	endothelin 1	Bos taurus	240-244
34819665-5	2021	Here we report crystal structures of the extracellular glycine-rich domain (GRD) of ALK, which regulates receptor activity by binding to activating peptides8,9.	Glycine	55-62	ALK receptor tyrosine kinase	Homo sapiens	84-87
34819665-7	2021	We show that repetitive glycines in the GRD form rigid helices that separate the major ligand-binding site from a distal polyglycine extension loop (PXL) that mediates ALK dimerization.	Glycine	24-32	ALK receptor tyrosine kinase	Homo sapiens	168-171
34419537-2	2021	In our previous study, we identified a novel mutation in exon 4 of the CRYBA1/BA3 gene, which resulted in the deletion of a highly conserved glycine at codon 91 (G91del) and perinuclear zonular cataract.	Glycine	141-148	crystallin beta A1	Homo sapiens	71-77
34515347-2	2021	Here we show that the glycine arginine rich (GAR) domain of nucleolin drives subcellular localization via protein-protein interactions with a kinesin light chain.	Glycine	22-29	nucleolin	Mus musculus	60-69
34901697-4	2021	At the time that amino acid glycine is mutated, KRAS protein acquires oncogenic properties that result in the tumor cell growth, proliferation, and cancer progression.	Glycine	28-35	KRAS proto-oncogene, GTPase	Homo sapiens	48-52
34635505-5	2022	Our data show that FLT3-ITD constitutively activates the STAT5 signaling pathway, which upregulates the expression of glycine amidinotransferase (GATM), the first rate-limiting enzyme of de novo creatine biosynthesis.	Glycine	118-125	glycine amidinotransferase	Homo sapiens	146-150
34139067-3	2021	Inspired by enzymatic aldol reaction of glycine, we successfully developed asymmetric aldol reaction of glycinate 5 and trifluoromethyl ketones 4 with 0.1-0.0033 mol% of chiral N-methyl pyridoxal 7a as the catalyst, producing chiral beta-trifluoromethyl-beta-hydroxy-alpha-amino acid esters 6 in 55-82% yields (for the syn-diastereomers) with up to >20:1 dr and 99% ee under very mild conditions.	Glycine	40-47	synemin	Homo sapiens	319-322
34380502-8	2021	This new RNA base editor was then used to induce 177Ser/Gly conversion of inhibitor kappa B kinase beta (IKKbeta) by changing the genetic code from AGU to GGU.	Glycine	56-59	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	105-112
34380502-10	2021	The 177Ser/Gly conversion of IKKbeta, accomplished by converting the genetic code from AGU to GGU, resulted in a decrease in the phosphorylation of IKKbeta and downregulation of downstream IKKbeta-related genes.	Glycine	11-14	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	29-36
34380502-10	2021	The 177Ser/Gly conversion of IKKbeta, accomplished by converting the genetic code from AGU to GGU, resulted in a decrease in the phosphorylation of IKKbeta and downregulation of downstream IKKbeta-related genes.	Glycine	11-14	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	148-155
34380502-10	2021	The 177Ser/Gly conversion of IKKbeta, accomplished by converting the genetic code from AGU to GGU, resulted in a decrease in the phosphorylation of IKKbeta and downregulation of downstream IKKbeta-related genes.	Glycine	11-14	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	189-196
34342855-3	2022	Integrins recognize oligopeptides present on ECM proteins and are involved in three main types of interaction, namely with collagen, laminin, and the oligopeptide RGD (Arg-Gly-Asp) present on vitronectin and fibronectin proteins.	Glycine	172-175	vitronectin	Homo sapiens	192-203
34233182-5	2021	Loss of SNX27 or CaMKIIalpha function blocks the glycine-induced increase in GluN2A-NMDARs on the neuronal membrane.	Glycine	49-56	sorting nexin 27	Homo sapiens	8-13
34085156-8	2022	LPS increased the apoptosis of jejunum and colon epithelial cells and protein abundance of cleaved caspase3 in the jejunum, which were markedly abrogated by Gly.	Glycine	157-160	caspase 3	Mus musculus	99-107
34085156-11	2022	In addition, Gly supplementation attenuated infiltration of CD4+, CD8+ T-lymphocytes, CD11b+ and F4/80+ macrophages in the colon.	Glycine	13-16	CD4 antigen	Mus musculus	60-63
34085156-11	2022	In addition, Gly supplementation attenuated infiltration of CD4+, CD8+ T-lymphocytes, CD11b+ and F4/80+ macrophages in the colon.	Glycine	13-16	adhesion G protein-coupled receptor E1	Mus musculus	97-102
34471049-7	2021	Accordingly, in a coactivator recruitment assay, saroglitazar activated PPARalpha-LBD and PPARgamma-LBD but not PPARdelta-LBD, whereas glycine substitution of either Trp228, Arg248, or both of PPARdelta-LBD conferred saroglitazar concentration-dependent activation.	Glycine	135-142	peroxisome proliferator activated receptor delta	Homo sapiens	193-202
35508169-0	2022	Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML.	Glycine	25-32	protein arginine methyltransferase 7	Homo sapiens	8-13
35508169-4	2022	Mechanistically, loss of PRMT7 resulted in reduced expressions of glycine decarboxylase, leading to the reprograming of glycine metabolism to generate methylglyoxal, which is detrimental to LSCs.	Glycine	120-127	protein arginine methyltransferase 7	Homo sapiens	25-30
35508169-5	2022	These findings link histone arginine methylation with glycine metabolism, while suggesting PRMT7 as a potential therapeutic target for the eradication of LSCs in CML.	Glycine	54-61	protein arginine methyltransferase 7	Homo sapiens	91-96
35490768-8	2022	Also, Gly promoted endomitotic DNA synthesis in silk gland cells via phosphoinositide 3-kinase (PI3K)/Akt/target of rapamycin (TOR) signaling.	Glycine	6-9	RAC serine/threonine-protein kinase	Bombyx mori	102-105
35579101-5	2022	After instillation, the presence of integrin-beta1 endows coated nanoparticles with steady adhesion via specific binding to Arg-Gly-Asp sequence on the fibronectin of ocular epithelium, achieving durable retention on ocular surface.	Glycine	128-131	integrin subunit beta 1	Homo sapiens	36-50
35212811-0	2022	The role of SHMT2 in modulating lipid metabolism in hepatocytes via glycine-mediated mTOR activation.	Glycine	68-75	serine hydroxymethyltransferase 2 (mitochondrial)	Mus musculus	12-17
35212811-1	2022	Serine hydroxymethyltransferase 2 (SHMT2) converts serine into glycine in the mitochondrial matrix, transferring a methyl group to tetrahydrofolate.	Glycine	63-70	serine hydroxymethyltransferase 2 (mitochondrial)	Mus musculus	0-33
35212811-1	2022	Serine hydroxymethyltransferase 2 (SHMT2) converts serine into glycine in the mitochondrial matrix, transferring a methyl group to tetrahydrofolate.	Glycine	63-70	serine hydroxymethyltransferase 2 (mitochondrial)	Mus musculus	35-40
35212811-6	2022	SHMT2 KD hepatocytes showed decreased lipid accumulation with reduced glycine levels compared to the scramble cells, which was restored upon reintroducing SHMT2.	Glycine	70-77	serine hydroxymethyltransferase 2 (mitochondrial)	Mus musculus	0-5
35212811-9	2022	We also showed that glycine activated mTOR/PPARgamma signaling and identified glycine as a mediator of SHMT2-responsive lipid accumulation in hepatocytes.	Glycine	78-85	serine hydroxymethyltransferase 2 (mitochondrial)	Mus musculus	103-108
35212811-10	2022	In conclusion, silencing SHMT2 in hepatocytes ameliorates lipid accumulation via the glycine-mediated mTOR/PPARgamma pathway.	Glycine	85-92	serine hydroxymethyltransferase 2 (mitochondrial)	Mus musculus	25-30
35571374-2	2022	Rare missense variants and microdeletions in the X-linked GlyR alpha2 subunit gene (GLRA2) have been associated with human autism spectrum disorder (ASD), where they typically cause a loss-of-function via protein truncation, reduced cell-surface trafficking and/or reduced glycine sensitivity (e.g., GLRA2Deltaex8-9 and extracellular domain variants p.N109S and p.R126Q).	Glycine	273-280	glycine receptor alpha 2	Homo sapiens	84-89
2141206-2	1990	The penultimate Gly in nsP1 or nsP2 or both was substituted by Ala, Val, or Glu, and processing was studied in vitro.	Glycine	16-19	SH2 domain containing 3A	Homo sapiens	23-27
2163012-3	1990	Additionally, reduction of glycine binding by the C-5 antagonists was reversed by both NMDA receptor agonists and C-7 competitive NMDA antagonists, providing evidence that the site of action of these C-5 antagonists is the NMDA recognition site, resulting in indirect modulation of the glycine site.	Glycine	27-34	complement C7	Homo sapiens	114-117
2163012-3	1990	Additionally, reduction of glycine binding by the C-5 antagonists was reversed by both NMDA receptor agonists and C-7 competitive NMDA antagonists, providing evidence that the site of action of these C-5 antagonists is the NMDA recognition site, resulting in indirect modulation of the glycine site.	Glycine	286-293	complement C7	Homo sapiens	114-117
2163012-4	1990	These data imply a functional coupling between the NMDA and associated glycine recognition sites and, furthermore, suggest a differential interaction of C-5 and C-7 competitive NMDA antagonists with the NMDA receptor complex.	Glycine	71-78	complement C7	Homo sapiens	161-164
2196964-5	1990	The same depressant effect was observed in animals pretreated with the monoamine oxidase B inhibitor (IMAO-B) deprenyl which is known to reduce milacemide metabolism into glycinamide and glycine.	Glycine	187-194	monoamine oxidase B	Homo sapiens	71-90
1970141-1	1990	Binding of benzodiazepines to the benzodiazepine gamma-aminobutyric acid (GABA) receptor-chloride channel complex has been shown to be altered by Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2).	Glycine	169-172	predicted gene 4924	Mus musculus	150-155
2404571-0	1990	Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers.	Glycine	0-7	KRAS proto-oncogene, GTPase	Homo sapiens	54-62
2404571-6	1990	In all three mutations of c-Ki-ras at codon 13 which had been seldom found in human cancers, glycine to aspartic acid mutations due to identical G to A transition at the second nucleotide were observed.	Glycine	93-100	KRAS proto-oncogene, GTPase	Homo sapiens	26-34
1715119-7	1990	In spite of the cross-reactivity for binding to vWF, only the two antibodies whose epitopes included residues in the Arg-Gly-Asp sequence inhibited vWF interaction with GP IIb-IIIa.	Glycine	121-124	integrin subunit alpha 2b	Homo sapiens	169-175
2241479-8	1990	of glycin proved less effective than that of arginine with regard to higher levels of insulin and total alpha-amino-N.	Glycine	3-9	LOC105613195	Ovis aries	86-93
33772775-4	2021	Mechanism studies revealed that glycine could decrease urine oxalate through downregulating Slc26a6 expression, whereas increase urine citrate via inhibiting Nadc1 expression.	Glycine	32-39	solute carrier family 26 member 6	Homo sapiens	92-99
33772775-5	2021	Moreover, glycine decreased the protein expression of both Slc26a6 and Nadc1 via increasing the expression of miRNA-411-3p, which directly bound to the 3"-untranslated regions of Slc26a6 and Nadc1 messenger RNAs, in vitro and in vivo.	Glycine	10-17	solute carrier family 26 member 6	Homo sapiens	59-66
33772775-5	2021	Moreover, glycine decreased the protein expression of both Slc26a6 and Nadc1 via increasing the expression of miRNA-411-3p, which directly bound to the 3"-untranslated regions of Slc26a6 and Nadc1 messenger RNAs, in vitro and in vivo.	Glycine	10-17	solute carrier family 26 member 6	Homo sapiens	179-186
33807656-3	2021	All six beta-type connexins expressed in human epidermis (Cx26, Cx30, Cx30.3, Cx31, Cx31.1 and Cx32) contain a glycine at position 12 (G12).	Glycine	111-118	gap junction protein beta 3	Homo sapiens	78-82
33807656-3	2021	All six beta-type connexins expressed in human epidermis (Cx26, Cx30, Cx30.3, Cx31, Cx31.1 and Cx32) contain a glycine at position 12 (G12).	Glycine	111-118	gap junction protein beta 5	Homo sapiens	84-90
33807656-3	2021	All six beta-type connexins expressed in human epidermis (Cx26, Cx30, Cx30.3, Cx31, Cx31.1 and Cx32) contain a glycine at position 12 (G12).	Glycine	111-118	gap junction protein beta 1	Homo sapiens	95-99
7925381-6	1994	However, in contrast to the other nuclear hormone receptor DNA-binding domains, the RXR domain contains a third helix immediately after the conserved Gly-Met sequence that signals the termination of the second helix.	Glycine	150-153	retinoid X receptor alpha	Homo sapiens	84-87
1531632-1	1992	Among the few proteins of the eukaryotic nucleolus that have been characterized, four proteins, nucleolin, fibrillarin, SSB1 and NSR1, possess a common structural motif, the GAR domain, which is rich in glycine and arginine residues.	Glycine	203-210	Hsp70 family ATPase SSB1	Saccharomyces cerevisiae S288C	120-124
1531632-1	1992	Among the few proteins of the eukaryotic nucleolus that have been characterized, four proteins, nucleolin, fibrillarin, SSB1 and NSR1, possess a common structural motif, the GAR domain, which is rich in glycine and arginine residues.	Glycine	203-210	Nsr1p	Saccharomyces cerevisiae S288C	129-133
34920161-7	2022	GTP molecule for wildtype had a low torsional strain of 10.71, and is the only molecule, in comparison to KRAS mutant bound GTP, to have a glycine at position 10 interacting with its nitrogenous base.	Glycine	139-146	KRAS proto-oncogene, GTPase	Homo sapiens	106-110
34563889-3	2022	In this study, we designed a new type of voltammetric biosensor, composed of a glycine-methionine dipeptide conjugated covalently to ferrocene (Gly-Met-Fc), for fast and ultrasensitive detection of the active form of MMP-9 in plasma samples.	Glycine	79-86	matrix metallopeptidase 9	Homo sapiens	217-222
34563889-6	2022	The cysteamine layer directly anchored to the gold surface ensured that the packing density of Gly-Met-Fc in the receptor layer was appropriate for the sensitive detection of MMP-9 in its active form.	Glycine	95-98	matrix metallopeptidase 9	Homo sapiens	175-180
34525858-3	2021	Besides, similar to PBA, D4F inhibited gly-HDL-induced ER stress response activation evaluated through the decreased PERK and eIF2alpha phosphorylation, together with reduced ATF6 nuclear translocation as well as the downregulation of GRP78 and CHOP.	Glycine	39-42	eukaryotic translation initiation factor 2 alpha kinase 3	Mus musculus	117-121
34917610-7	2021	Gly supplementation could reduce the ER stress induced by TG by significantly improving the ER levels and significantly downregulating the expression of genes related to ER stress (Xbp1, ATF4, and ATF6).	Glycine	0-3	activating transcription factor 4	Homo sapiens	187-191
34676744-2	2021	On the other hand, glycine-rich sequences, mainly present in tropoelastin terminal domains, are responsible for the elastin self-assembly.	Glycine	19-26	elastin	Homo sapiens	116-123
34676744-3	2021	In a previous study, we have recombinantly expressed a chimeric polypeptide, named resilin, elastin, and collagen (REC), inspired by glycine-rich motifs of elastin and containing resilin and collagen sequences as well.	Glycine	133-140	elastin	Homo sapiens	92-99
34676744-3	2021	In a previous study, we have recombinantly expressed a chimeric polypeptide, named resilin, elastin, and collagen (REC), inspired by glycine-rich motifs of elastin and containing resilin and collagen sequences as well.	Glycine	133-140	elastin	Homo sapiens	156-163
34418357-1	2021	The enzymes glycine amidinotransferase, mitochondrial (GATM also known as AGAT) and guanidinoacetate N-methyltransferase (GAMT) function together to synthesize creatine from arginine, glycine, and S-Adenosyl methionine.	Glycine	12-19	glycine amidinotransferase	Homo sapiens	55-59
34418357-1	2021	The enzymes glycine amidinotransferase, mitochondrial (GATM also known as AGAT) and guanidinoacetate N-methyltransferase (GAMT) function together to synthesize creatine from arginine, glycine, and S-Adenosyl methionine.	Glycine	184-191	glycine amidinotransferase	Homo sapiens	55-59
34418357-1	2021	The enzymes glycine amidinotransferase, mitochondrial (GATM also known as AGAT) and guanidinoacetate N-methyltransferase (GAMT) function together to synthesize creatine from arginine, glycine, and S-Adenosyl methionine.	Glycine	184-191	glycine amidinotransferase	Homo sapiens	74-78
34688657-3	2021	Some forms of inherited intellectual disability (ID) have been associated with a serine-to-leucine substitution in the SRM (S132L mutation) and a glycine-to-arginine substitution outside the SRM (G243R mutation) in CERT; however, it is unclear if mutations outside the SRM disrupt the control of CERT functionality.	Glycine	146-153	ceramide transporter 1	Homo sapiens	215-219
34610306-4	2021	We reveal that two CAP-Gly domains in CYLD are ubiquitin-binding domains and demonstrate a requirement of CAP-Gly3 for CYLD activity and regulation of immune receptor signaling.	Glycine	23-26	CYLD lysine 63 deubiquitinase	Homo sapiens	38-42
34610306-4	2021	We reveal that two CAP-Gly domains in CYLD are ubiquitin-binding domains and demonstrate a requirement of CAP-Gly3 for CYLD activity and regulation of immune receptor signaling.	Glycine	23-26	CYLD lysine 63 deubiquitinase	Homo sapiens	119-123
34347214-1	2021	S-adenosylmethionine (AdoMet) predominantly accumulates in tissues and biological fluids of patients affected by liver dysmethylating diseases, particularly glycine N-methyltransferase, S-adenosylhomocysteine hydrolase and adenosine kinase deficiencies, as well as in some hepatic mtDNA depletion syndromes, whose pathogenesis of liver dysfunction is still poorly established.	Glycine	157-164	methionine adenosyltransferase 1A	Rattus norvegicus	22-28
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	15-22	zyg-11 family member B, cell cycle regulator	Homo sapiens	62-68
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	15-22	Cbl proto-oncogene like 2	Homo sapiens	124-143
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	15-22	DAN domain BMP antagonist family member 5	Homo sapiens	145-149
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	31-34	zyg-11 family member B, cell cycle regulator	Homo sapiens	62-68
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	31-34	Cbl proto-oncogene like 2	Homo sapiens	124-143
34214466-3	2021	The N-terminal glycine degron (Gly/N-degron) is recognized by ZYG11B and ZER1, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2).	Glycine	31-34	DAN domain BMP antagonist family member 5	Homo sapiens	145-149
34214466-5	2021	The structures reveal that ZYG11B and ZER1 utilize their armadillo (ARM) repeats forming a deep and narrow cavity to engage mainly the first four residues of Gly/N-degrons.	Glycine	158-161	zyg-11 family member B, cell cycle regulator	Homo sapiens	27-33
34476002-2	2021	In a variety of human tumours, including hepatocellular carcinoma (HCC), breast cancer and non-small-cell lung cancer (NSCLC), a large amount of carbon is reused in serine/glycine biosynthesis, accompanied by higher expression of the key glycine synthetic enzyme mitochondrial serine hydroxymethyltransferase 2 (SHMT2).	Glycine	172-179	serine hydroxymethyltransferase 2	Homo sapiens	312-317
34476002-2	2021	In a variety of human tumours, including hepatocellular carcinoma (HCC), breast cancer and non-small-cell lung cancer (NSCLC), a large amount of carbon is reused in serine/glycine biosynthesis, accompanied by higher expression of the key glycine synthetic enzyme mitochondrial serine hydroxymethyltransferase 2 (SHMT2).	Glycine	238-245	serine hydroxymethyltransferase 2	Homo sapiens	312-317
34621433-6	2021	Results: In P no missense mutations were found in the HCN4 gene; instead, we found two heterozygous variants in the HCN1 gene: deletion of an N-terminal glycine triplet (72GGG74, "N-del") and a novel missense variant, P851A, in the C-terminal region.	Glycine	153-160	hyperpolarization activated cyclic nucleotide gated potassium channel 1	Homo sapiens	116-120
34306033-3	2021	Based on population studies, clusters in COL1A1 and COL1A2 genes associated with the presence of glycine substitutions leading to fatal outcome have been distinguished and named as "lethal regions."	Glycine	97-104	collagen type I alpha 1 chain	Homo sapiens	41-47
34306033-9	2021	Finally, we identified six glycine substitutions located in lethal regions of COL1A1 and COL1A2 genes, of which four are novel.	Glycine	27-34	collagen type I alpha 1 chain	Homo sapiens	78-84
34306033-10	2021	The review of all mutations in the dedicated OI database, revealed 33 distinct glycine substitutions in two lethal domains of COL1A1, 26 of which have been associated with a fatal outcome.	Glycine	79-86	collagen type I alpha 1 chain	Homo sapiens	126-132
34306033-12	2021	An analysis of all glycine substitutions leading to fatal phenotype, showed that their distribution along collagen type I genes is not regular, with 17% (26 out of 154) of mutations reported in COL1A1 and 64% (51 out of 80) in COL1A2 corresponding to localization of the lethal regions.	Glycine	19-26	collagen type I alpha 1 chain	Homo sapiens	194-200
34161704-1	2021	BACKGROUND: Clinical trials of the KRAS inhibitors adagrasib and sotorasib have shown promising activity in cancers harboring KRAS glycine-to-cysteine amino acid substitutions at codon 12 (KRASG12C).	Glycine	131-138	KRAS proto-oncogene, GTPase	Homo sapiens	35-39
34161704-1	2021	BACKGROUND: Clinical trials of the KRAS inhibitors adagrasib and sotorasib have shown promising activity in cancers harboring KRAS glycine-to-cysteine amino acid substitutions at codon 12 (KRASG12C).	Glycine	131-138	KRAS proto-oncogene, GTPase	Homo sapiens	126-130
35398308-1	2022	Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme that regulates serine/glycine transition; however, its specific function and molecular mechanisms in tumors remain controversial.	Glycine	80-87	serine hydroxymethyltransferase 2	Homo sapiens	0-33
35398308-1	2022	Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme that regulates serine/glycine transition; however, its specific function and molecular mechanisms in tumors remain controversial.	Glycine	80-87	serine hydroxymethyltransferase 2	Homo sapiens	35-40
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	claudin 1	Mus musculus	121-130
35085745-9	2022	GLY also protected the intestinal mucosal barrier by increasing the expression of the tight junction proteins, occludin, claudin-1 and ZO-1 and by reducing the serum LPS content and decreasing the expression of TLR4, MyD88, NF-kappaB, IL-6, IL-1beta, and TNF-alpha proteins in colon.	Glycine	0-3	myeloid differentiation primary response gene 88	Mus musculus	217-222
35139220-3	2022	Arabidopsis (Arabidopsis thaliana) mutants lacking ER-ANT1 (er-ant1 plants) exhibit a photorespiratory phenotype accompanied by high glycine levels and stunted growth, pointing to an inhibition of glycine decarboxylase.	Glycine	133-140	endoplasmic reticulum-adenine nucleotide transporter 1	Arabidopsis thaliana	60-67
35139220-3	2022	Arabidopsis (Arabidopsis thaliana) mutants lacking ER-ANT1 (er-ant1 plants) exhibit a photorespiratory phenotype accompanied by high glycine levels and stunted growth, pointing to an inhibition of glycine decarboxylase.	Glycine	197-204	endoplasmic reticulum-adenine nucleotide transporter 1	Arabidopsis thaliana	60-67
35427200-4	2022	Both ATG10 and the C-terminal glycine of ATG12 are essential for the canonical ubiquitin-like conjugation of ATG12 and ATG5.	Glycine	30-37	Atg12p	Saccharomyces cerevisiae S288C	41-46
35427200-4	2022	Both ATG10 and the C-terminal glycine of ATG12 are essential for the canonical ubiquitin-like conjugation of ATG12 and ATG5.	Glycine	30-37	Atg12p	Saccharomyces cerevisiae S288C	109-114
35427200-5	2022	However, loss of ATG10 or the C-terminal glycine of ATG12 occurred at least 16 times in a wide range of lineages, suggesting that possible covalent-to-non-covalent transition is not limited to the species that we previously reported such as Alveolata and some yeast species.	Glycine	41-48	Atg12p	Saccharomyces cerevisiae S288C	52-57
35211429-1	2022	Introduction: Serine hydroxymethyltransferase 2 (SHMT2) has a critical role in serine-glycine metabolism to drive cancer cell proliferation.	Glycine	86-93	serine hydroxymethyltransferase 2	Homo sapiens	14-47
35211429-1	2022	Introduction: Serine hydroxymethyltransferase 2 (SHMT2) has a critical role in serine-glycine metabolism to drive cancer cell proliferation.	Glycine	86-93	serine hydroxymethyltransferase 2	Homo sapiens	49-54
35150347-9	2022	GEO data revealed that gamma-tocotrienol (g-T3), NSC319726, and Casiopeina Cas-II-gly may reduce the expression of, NDUFAF1, CCNB1, DKK1 genes, respectively (P < 0.01).	Glycine	82-85	NADH:ubiquinone oxidoreductase complex assembly factor 1	Homo sapiens	116-123
34623442-8	2022	Moreover, the single nucleotide polymorphisms affecting the expression of THREONINE ALDOLASE 1 (THA1) and the amino acid transporter gene AVT1B, respectively, only underlie the variation in threonine and glycine levels in the dark.	Glycine	204-211	threonine aldolase 1	Arabidopsis thaliana	74-94
34623442-8	2022	Moreover, the single nucleotide polymorphisms affecting the expression of THREONINE ALDOLASE 1 (THA1) and the amino acid transporter gene AVT1B, respectively, only underlie the variation in threonine and glycine levels in the dark.	Glycine	204-211	threonine aldolase 1	Arabidopsis thaliana	96-100
35422087-1	2022	Mitochondrial serine hydroxymethyltransferase (SHMT2) catalyzes the conversion of serine to glycine and concomitantly produces one-carbon units to support cell growth and is upregulated in various cancer cells.	Glycine	92-99	serine hydroxymethyltransferase 2	Homo sapiens	0-45
35422087-1	2022	Mitochondrial serine hydroxymethyltransferase (SHMT2) catalyzes the conversion of serine to glycine and concomitantly produces one-carbon units to support cell growth and is upregulated in various cancer cells.	Glycine	92-99	serine hydroxymethyltransferase 2	Homo sapiens	47-52
35077997-1	2022	Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S-S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively.	Glycine	98-101	thioredoxin reductase 1	Homo sapiens	38-52
35207427-0	2022	A Rationalization of the Effect That TMAO, Glycine, and Betaine Exert on the Collapse of Elastin-like Polypeptides.	Glycine	43-50	elastin	Homo sapiens	89-96
35186396-2	2022	The various genes causing severe OI include WNT1 , SERPINF1 , P3H1 , CREB3L1 , and CRTAP , although glycine substitutions in COL1A1chains have also been predicted to cause perinatal lethal OI .	Glycine	100-107	collagen type I alpha 1 chain	Homo sapiens	125-131
27798331-0	2016	Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts.	Glycine	0-7	F-box protein 32	Homo sapiens	124-133
27798331-11	2016	Moreover, glycine addition resulted in decreased mRNA levels for atrogin-1 and MuRF1 (by 20-40% and 30-50%, respectively; P &lt; 0.05).	Glycine	10-17	F-box protein 32	Homo sapiens	65-74
27654951-6	2016	A MS-based interactome study revealed that the glycine substitutions facilitate binding of B/NS1 to heat shock protein 90-beta (HSP90beta).	Glycine	47-54	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	93-96
26905697-1	2016	PURPOSE: Multimeric arginine-glycine-aspartic acid (RGD) peptides have advantages for imaging integrin alphavbeta3 expression.	Glycine	29-36	integrin subunit alpha V	Homo sapiens	94-114
27514743-4	2016	The N-terminal Gly/Arg-rich domain (GAR domain) of TRF2 directly binds to the globular domain of core histones.	Glycine	15-18	telomeric repeat binding factor 2	Homo sapiens	51-55
27519266-12	2016	The majority of identified COL1A1/2 pathogenic variants occurred in a glycine substitution (36/56, 64.3 %), usually serine (23/36, 63.9 %).	Glycine	70-77	collagen type I alpha 1 chain	Homo sapiens	27-33
27489855-3	2016	In the present study, the three cysteine residues present in the carboxyl-terminus of the human FSHR were replaced with glycine by site-directed mutagenesis.	Glycine	120-127	follicle stimulating hormone receptor	Homo sapiens	96-100
26774659-1	2016	BACKGROUND: The Gly-to-Arg substitution at the 16 position (rs1042713) in the beta2-adrenoceptor gene (ADRB2) is associated with enhanced downregulation and uncoupling of beta2-receptors.	Glycine	16-19	adrenoceptor beta 2	Homo sapiens	78-96
26774659-1	2016	BACKGROUND: The Gly-to-Arg substitution at the 16 position (rs1042713) in the beta2-adrenoceptor gene (ADRB2) is associated with enhanced downregulation and uncoupling of beta2-receptors.	Glycine	16-19	adrenoceptor beta 2	Homo sapiens	103-108
27282200-7	2016	According to all predictors, mutation in KCNH1 is damaging de novo mutation that results in substitution of Glycine by Arginine, i.e., p.(Gly348Arg).	Glycine	108-115	potassium voltage-gated channel subfamily H member 1	Homo sapiens	41-46
27230112-0	2016	Glycine confers neuroprotection through microRNA-301a/PTEN signaling.	Glycine	0-7	microRNA 301a	Rattus norvegicus	40-53
27230112-0	2016	Glycine confers neuroprotection through microRNA-301a/PTEN signaling.	Glycine	0-7	phosphatase and tensin homolog	Rattus norvegicus	54-58
27230112-5	2016	In this study, we aimed to determine whether glycine-induced neuroprotection requires microRNA-301a-dependent signaling.	Glycine	45-52	microRNA 301a	Rattus norvegicus	86-99
27230112-6	2016	RESULTS: We provided the first evidence that glycine increased the expression of microRNA-301a in cultured rat cortical neurons and protected against cortical neuronal death through up-regulation of microRNA-301a after oxygen-glucose deprivation.	Glycine	45-52	microRNA 301a	Rattus norvegicus	81-94
27230112-6	2016	RESULTS: We provided the first evidence that glycine increased the expression of microRNA-301a in cultured rat cortical neurons and protected against cortical neuronal death through up-regulation of microRNA-301a after oxygen-glucose deprivation.	Glycine	45-52	microRNA 301a	Rattus norvegicus	199-212
27230112-8	2016	We revealed that PTEN down-regulation by microRNA-301a mediated glycine-induced neuroprotective effect following oxygen-glucose deprivation.	Glycine	64-71	phosphatase and tensin homolog	Rattus norvegicus	17-21
27230112-8	2016	We revealed that PTEN down-regulation by microRNA-301a mediated glycine-induced neuroprotective effect following oxygen-glucose deprivation.	Glycine	64-71	microRNA 301a	Rattus norvegicus	41-54
27230112-9	2016	CONCLUSIONS: Our results suggest that 1) microRNA-301a is neuroprotective in oxygen-glucose deprivation-induced neuronal injury; 2) glycine is an upstream regulator of microRNA-301a; 3) glycine confers neuroprotection through microRNA-301a/PTEN signal pathway.	Glycine	132-139	microRNA 301a	Rattus norvegicus	41-54
27230112-9	2016	CONCLUSIONS: Our results suggest that 1) microRNA-301a is neuroprotective in oxygen-glucose deprivation-induced neuronal injury; 2) glycine is an upstream regulator of microRNA-301a; 3) glycine confers neuroprotection through microRNA-301a/PTEN signal pathway.	Glycine	132-139	microRNA 301a	Rattus norvegicus	168-181
27230112-9	2016	CONCLUSIONS: Our results suggest that 1) microRNA-301a is neuroprotective in oxygen-glucose deprivation-induced neuronal injury; 2) glycine is an upstream regulator of microRNA-301a; 3) glycine confers neuroprotection through microRNA-301a/PTEN signal pathway.	Glycine	132-139	microRNA 301a	Rattus norvegicus	168-181
27230112-9	2016	CONCLUSIONS: Our results suggest that 1) microRNA-301a is neuroprotective in oxygen-glucose deprivation-induced neuronal injury; 2) glycine is an upstream regulator of microRNA-301a; 3) glycine confers neuroprotection through microRNA-301a/PTEN signal pathway.	Glycine	132-139	phosphatase and tensin homolog	Rattus norvegicus	240-244
27230112-9	2016	CONCLUSIONS: Our results suggest that 1) microRNA-301a is neuroprotective in oxygen-glucose deprivation-induced neuronal injury; 2) glycine is an upstream regulator of microRNA-301a; 3) glycine confers neuroprotection through microRNA-301a/PTEN signal pathway.	Glycine	186-193	microRNA 301a	Rattus norvegicus	41-54
26632638-0	2016	Erythrokeratoderma Variabilis Caused by p.Gly45Glu in Connexin 31: Importance of the First Extracellular Loop Glycine Residue for Gap Junction Function.	Glycine	110-117	gap junction protein beta 3	Homo sapiens	54-65
26890358-4	2016	In this work, the unprecedented increased enzymatic activity and intracellular penetration achieved by the association of a human recombinant GLA to nanoliposomes functionalized with Arginine-Glycine-Aspartic acid (RGD) peptides is reported.	Glycine	192-199	galactosidase alpha	Homo sapiens	142-145
27028208-3	2016	Although elastin-derived polypeptide (Val-Pro-Gly-Val-Gly)n also has been known to demonstrate coacervation property, a sufficiently high (VPGVG)n repetition number (n&gt;40) is required for coacervation.	Glycine	46-49	elastin	Homo sapiens	9-16
26804975-9	2016	In patients, PSP activity was negatively correlated with plasma d-serine and glycine levels.	Glycine	77-84	phosphoserine phosphatase	Homo sapiens	13-16
26824641-5	2016	As serine and glycine can be reversibly metabolized by serine hydroxymethyltransferase 2 (SHMT2), we assessed the abundance of SHMT2 transcript as well as its functional role by inhibiting it with aminomethylphosphonic acid (AMPA), a glycine analog, during in vitro culture.	Glycine	234-241	serine hydroxymethyltransferase 2	Homo sapiens	55-88
26824641-5	2016	As serine and glycine can be reversibly metabolized by serine hydroxymethyltransferase 2 (SHMT2), we assessed the abundance of SHMT2 transcript as well as its functional role by inhibiting it with aminomethylphosphonic acid (AMPA), a glycine analog, during in vitro culture.	Glycine	234-241	serine hydroxymethyltransferase 2	Homo sapiens	90-95
26824641-6	2016	Both AMPA supplementation and elevated glycine decreased the mRNA abundance of SHMT2 and tumor protein p53 (TP53), which is activated in response to cellular stress, compared to controls (P &lt;= 0.02).	Glycine	39-46	serine hydroxymethyltransferase 2	Homo sapiens	79-84
26836315-7	2016	The aae13-1 mutant exhibits typical metabolic phenotypes associated with a deficiency in the mitochondrial fatty acid synthase system, namely depleted lipoylation of the H subunit of the photorespiratory enzyme glycine decarboxylase, increased accumulation of glycine and glycolate and reduced levels of sucrose.	Glycine	211-218	AMP-dependent synthetase and ligase family protein	Arabidopsis thaliana	4-9
26859063-2	2016	In this work, we analyzed if Gly m Bd 28K/P28, one of the major soybean allergens, is a cross-reactive allergen with cow milk proteins (CMP).	Glycine	29-32	B cell receptor associated protein 31	Mus musculus	42-45
26364050-0	2016	Some Operational Characteristics of Glycine Release in Rat Retina: The Role of Reverse Mode Operation of Glycine Transporter Type-1 (GlyT-1) in Ischemic Conditions.	Glycine	36-43	solute carrier family 6 member 9	Rattus norvegicus	105-131
26364050-0	2016	Some Operational Characteristics of Glycine Release in Rat Retina: The Role of Reverse Mode Operation of Glycine Transporter Type-1 (GlyT-1) in Ischemic Conditions.	Glycine	36-43	solute carrier family 6 member 9	Rattus norvegicus	133-139
26857796-3	2016	Glycine and D-serine are endogenous ligands to the NMDA modulatory site, but since high doses are needed to affect brain levels, related compounds are being developed, for example glycine transport (GlyT) inhibitors to potentially elevate brain glycine or targeting enzymes, such as D-amino acid oxidase (DAAO) to slow the breakdown and increase the brain level of D-serine.	Glycine	0-7	D-amino acid oxidase	Mus musculus	305-309
27048272-2	2016	Two high-affinity and substrate selective transporters, glycine transporter-1 and glycine transporter-2 (GlyT-1 and GlyT-2), regulate extracellular glycine concentrations within the CNS and as such, play critical roles in maintaining a balance between inhibitory and excitatory neurotransmission.	Glycine	56-63	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	116-122
26200505-12	2015	We conclude that BDNF, acting on TrkB-T1 receptors, inhibits glycine uptake in astrocytes by promoting GlyT internalization through a Rho-GTPase activity dependent mechanism.	Glycine	61-68	brain-derived neurotrophic factor	Rattus norvegicus	17-21
26482881-4	2015	We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production.	Glycine	61-68	serine hydroxymethyltransferase 2	Homo sapiens	112-117
26482881-4	2015	We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production.	Glycine	61-68	activating transcription factor 4	Homo sapiens	122-126
26302655-4	2015	Using two different rodent models of temporal lobe epilepsy (TLE)--the intrahippocampal kainic acid model of TLE in mice, and the rat model of tetanic stimulation-induced TLE--we first demonstrated robust overexpression of GlyT1 in the hippocampal formation, suggesting dysfunctional glycine signaling in epilepsy.	Glycine	284-291	solute carrier family 6 member 9	Rattus norvegicus	223-228
26703626-6	2015	We found that SH, M-Gly, and P334 have significant effects on the wound healing process in human keratinocytes and these effects were mediated by activation of focal adhesion kinases (FAK), extracellular signal-regulated kinases (ERK), and c-Jun N-terminal kinases (JNK).	Glycine	20-23	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	240-245
26506308-5	2015	Expression of the microtubule-anchoring CAP-GLY domain of CLIP170 fused to the nuclear-envelope-anchoring KASH domain of nesprin rescues nuclear positioning defects of amph-1 mutants.	Glycine	44-47	CAP-Gly domain containing linker protein 1	Homo sapiens	58-65
26332921-3	2015	Structural studies have revealed that the C-terminal glycine of ubiquitin and ubiquitin-like proteins adopts a syn (psi ~ 0 ) or gauche (psi ~ +-60 ) conformation upon interacting with deubiquitinases/ubiquitin-like proteases.	Glycine	53-60	synemin	Homo sapiens	111-114
26271101-4	2015	RNA bisulfite sequencing revealed that Dnmt2 methylates C38 of tRNA Asp(GTC), Gly(GCC), and Val(AAC), thus preventing tRNA fragmentation.	Glycine	78-81	tRNA aspartic acid methyltransferase 1	Mus musculus	39-44
26067360-7	2015	They also showed an exercise-induced compensatory regulation of genes involved in biosynthesis and metabolism of amino acids (PSPH, GATM, NOS1 and GLDC), which responded to differences in the amino acid profile (consistently lower plasma levels of glycine, cysteine and arginine).	Glycine	248-255	phosphoserine phosphatase	Homo sapiens	126-130
26067360-7	2015	They also showed an exercise-induced compensatory regulation of genes involved in biosynthesis and metabolism of amino acids (PSPH, GATM, NOS1 and GLDC), which responded to differences in the amino acid profile (consistently lower plasma levels of glycine, cysteine and arginine).	Glycine	248-255	glycine amidinotransferase	Homo sapiens	132-136
25869273-2	2015	OBJECTIVES: We investigated the efficacy of a glycine transporter 1 (GlyT1) inhibitor that potentiates NMDA receptor function by increasing synaptic glycine levels in animal models for cognitive dysfunction and negative symptoms, both of which are poorly managed by current antipsychotics.	Glycine	46-53	solute carrier family 6 member 9	Rattus norvegicus	69-74
26101830-11	2015	The co-expression of GlyT1 and NMDA receptors in DRG suggests that GlyT1 regulates glycine concentration at the glycine binding site of the NMDA receptor.	Glycine	83-90	solute carrier family 6 member 9	Rattus norvegicus	67-72
26101830-11	2015	The co-expression of GlyT1 and NMDA receptors in DRG suggests that GlyT1 regulates glycine concentration at the glycine binding site of the NMDA receptor.	Glycine	112-119	solute carrier family 6 member 9	Rattus norvegicus	21-26
26101830-11	2015	The co-expression of GlyT1 and NMDA receptors in DRG suggests that GlyT1 regulates glycine concentration at the glycine binding site of the NMDA receptor.	Glycine	112-119	solute carrier family 6 member 9	Rattus norvegicus	67-72
25957474-6	2015	In this study, we report that an HLD4-associated (Asp-29-to-Gly) mutant of mitochondrial heat shock 60-kDa protein 1 (HSPD1) causes short-length morphologies and increases the numbers of mitochondria due to their aberrant fission and fusion cycles.	Glycine	60-63	heat shock protein family D (Hsp60) member 1	Homo sapiens	33-37
25957474-6	2015	In this study, we report that an HLD4-associated (Asp-29-to-Gly) mutant of mitochondrial heat shock 60-kDa protein 1 (HSPD1) causes short-length morphologies and increases the numbers of mitochondria due to their aberrant fission and fusion cycles.	Glycine	60-63	heat shock protein family D (Hsp60) member 1	Homo sapiens	118-123
26240838-5	2015	Specifically, compared with undecorated gels, those functionalized with Arg-Gly-Asp-Ser (RGDS) peptides increase the proliferative activity of NSCs; promote their directional migration; induce differentiation, with increased expression of microtubule-associated protein-2, and a low expression of glial fibrillary acidic protein; and lead to the formation of larger neurospheres.	Glycine	76-79	ral guanine nucleotide dissociation stimulator	Mus musculus	89-93
25716890-10	2015	The cytosolic AtLAP1 (A. thaliana leucine aminopeptidase 1) and the putative chloroplastic AtLAP3 displayed activity towards Cys-Gly peptide through in vivo functional assays in yeast.	Glycine	129-132	Cytosol aminopeptidase family protein	Arabidopsis thaliana	14-20
25716890-10	2015	The cytosolic AtLAP1 (A. thaliana leucine aminopeptidase 1) and the putative chloroplastic AtLAP3 displayed activity towards Cys-Gly peptide through in vivo functional assays in yeast.	Glycine	129-132	Calcium-dependent phosphotriesterase superfamily protein	Arabidopsis thaliana	91-97
25999742-3	2015	Although the mitochondrial isoform of SHMT (SHMT2) has been proven to be a crucial factor in the serine/glycine metabolism in several cancer cell types, the expression pattern of SHMT2 and the correlation of expression level of SHMT2 and other clinicopathological parameters in clinical breast cancer remain to be explored.	Glycine	104-111	serine hydroxymethyltransferase 2	Homo sapiens	38-42
25999742-3	2015	Although the mitochondrial isoform of SHMT (SHMT2) has been proven to be a crucial factor in the serine/glycine metabolism in several cancer cell types, the expression pattern of SHMT2 and the correlation of expression level of SHMT2 and other clinicopathological parameters in clinical breast cancer remain to be explored.	Glycine	104-111	serine hydroxymethyltransferase 2	Homo sapiens	44-49
25958000-2	2015	OI often results from missense mutations in one of the conserved glycine residues present in the Gly-X-Y sequence repeats of the triple helical region of the collagen type I alpha chain, which is encoded by the COL1A1 gene.	Glycine	65-72	collagen type I alpha 1 chain	Homo sapiens	211-217
25958000-2	2015	OI often results from missense mutations in one of the conserved glycine residues present in the Gly-X-Y sequence repeats of the triple helical region of the collagen type I alpha chain, which is encoded by the COL1A1 gene.	Glycine	97-100	collagen type I alpha 1 chain	Homo sapiens	211-217
25533534-7	2015	Induction of c-Fos expression was observed in the hypothalamic nuclei, including the medial preoptic area (MPO) and the suprachiasmatic nucleus (SCN) shell after glycine administration.	Glycine	162-169	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	13-18
25542299-9	2015	RESULTS: Significantly superior activities were found in 34 of the approximately 2000 mutants analyzed, and the majority of the superior GSTs featured His and Gly residues in one of the three active-site positions subjected to mutagenesis.	Glycine	159-162	glutathione S-transferase alpha 2	Homo sapiens	137-141
25834055-1	2015	In healthy mature motoneurons (MNs), KCC2 cotransporters maintain the intracellular chloride concentration at low levels, a prerequisite for postsynaptic inhibition mediated by GABA and glycine.	Glycine	186-193	solute carrier family 12 member 5	Homo sapiens	37-41
25447237-3	2015	It has been shown in cell culture that the nuclear import of FUS is mediated by transportin, which binds the PY-NLS and the last arginine/glycine/glycine-rich (RGG) domain of FUS.	Glycine	138-145	Transportin	Drosophila melanogaster	80-91
25447237-3	2015	It has been shown in cell culture that the nuclear import of FUS is mediated by transportin, which binds the PY-NLS and the last arginine/glycine/glycine-rich (RGG) domain of FUS.	Glycine	146-153	Transportin	Drosophila melanogaster	80-91
25580690-3	2015	The hydantoin, 3-phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione (IM-3), synthesized from the amino acid, glycine, was selected for psychopharmacological studies in mice on the basis of its chemical and structural similarity with phenytoin.	Glycine	107-114	immunoregulatory 3	Mus musculus	67-71
25582325-2	2015	Further, Gly-AGEs not only evoke oxidative and inflammatory reactions in endothelial cells (ECs) through the interaction with a receptor for AGEs (RAGE), but also mimic vasopermeability effects of AGE-rich serum purified from diabetic patients on hemodialysis.	Glycine	9-12	long intergenic non-protein coding RNA 914	Homo sapiens	147-151
25582325-3	2015	These observations suggest that Gly-AGE-RAGE system might be a therapeutic target for vascular complications in diabetes.	Glycine	32-35	long intergenic non-protein coding RNA 914	Homo sapiens	40-44
25582325-10	2015	CONCLUSIONS: The present study suggests that GLAP might be a main glyceraldehyde-related AGE structure in Gly-AGEs that bound to RAGE and subsequently elicited ROS generation and inflammatory and thrombogenic reactions in HUVECs.	Glycine	106-109	long intergenic non-protein coding RNA 914	Homo sapiens	129-133
28509452-4	2015	We propose short peptides Lys-Glu, Lys-Glu-Asp, and Ala-Glu-Asp-Gly could influence on F11R gene expression that leads to recovery of JAM-A synthesis in cells.	Glycine	64-67	F11 receptor	Homo sapiens	87-91
28509452-4	2015	We propose short peptides Lys-Glu, Lys-Glu-Asp, and Ala-Glu-Asp-Gly could influence on F11R gene expression that leads to recovery of JAM-A synthesis in cells.	Glycine	64-67	F11 receptor	Homo sapiens	134-139
25578890-6	2015	The pyridazine-containing GlyT-1 inhibitors with in vitro GlyT-1 inhibitory potency also enhanced extracellular glycine concentrations in conscious rat striatum as was measured by microdialysis technique.	Glycine	112-119	solute carrier family 6 member 9	Rattus norvegicus	26-32
25578890-6	2015	The pyridazine-containing GlyT-1 inhibitors with in vitro GlyT-1 inhibitory potency also enhanced extracellular glycine concentrations in conscious rat striatum as was measured by microdialysis technique.	Glycine	112-119	solute carrier family 6 member 9	Rattus norvegicus	58-64
25551757-6	2014	The cysteine residues involved in the formation of the disulfide bridges in CD9 EC2 were all essential for inhibitory activity but a conserved glycine residue in the tetraspanin-defining "CCG" motif was not.	Glycine	143-150	CD9 molecule	Homo sapiens	76-79
25375264-4	2014	Associated with a high umami-enhancing activity (beta-value 5.1), N(2)-(propylthiomethyl)guanosine 5"-monophosphate could be generated when 5"-GMP reacted with glucose, glycine, and the onion-derived odorant 1-propanethiol, thus opening a valuable avenue to produce high-potency umami-enhancing chemosensorica from food-derived natural products by kitchen-type chemistry.	Glycine	169-176	5'-nucleotidase, cytosolic II	Homo sapiens	143-146
25109237-8	2014	Using click chemistry with wild type and an unmyristoylatable G2A mutant we demonstrate that FXR2P is N-myristoylated on glycine 2, establishing it as a lipid-modified RNA binding protein.	Glycine	121-128	FMR1 autosomal homolog 2	Homo sapiens	93-98
24993297-0	2014	BDNF-mediated modulation of glycine transmission on rat spinal motoneurons.	Glycine	28-35	brain-derived neurotrophic factor	Rattus norvegicus	0-4
24928908-4	2014	These variants reside in conserved residues in the KCC2 cytoplasmic C-terminus, exhibit significantly impaired Cl(-)-extrusion capacities resulting in less hyperpolarized Gly equilibrium potentials (EG ly), and impair KCC2 stimulatory phosphorylation at serine 940, a key regulatory site.	Glycine	171-174	solute carrier family 12 member 5	Homo sapiens	51-55
25909056-1	2014	BACKGROUND: The association between beta2-adrenergic receptor (ADRB2) -16Arg/Gly polymorphism (rs1042713) and chronic obstructive pulmonary disease (COPD) risk has been investigated in many published studies.	Glycine	77-80	adrenoceptor beta 2	Homo sapiens	36-61
25909056-1	2014	BACKGROUND: The association between beta2-adrenergic receptor (ADRB2) -16Arg/Gly polymorphism (rs1042713) and chronic obstructive pulmonary disease (COPD) risk has been investigated in many published studies.	Glycine	77-80	adrenoceptor beta 2	Homo sapiens	63-68
25909056-9	2014	CONCLUSION: This meta-analysis suggested that the ADRB2-16Arg/Gly polymorphism might be a potential risk factor for the development of COPD in smoking Asian populations, but not in European descendents, and tobacco smoking probably increased the genetic susceptibility.	Glycine	62-65	adrenoceptor beta 2	Homo sapiens	50-55
24794830-0	2014	A recurrent "hot spot" glycine substitution mutation, G2043R in COL7A1, induces dominant dystrophic epidermolysis bullosa associated with intracytoplasmic accumulation of pro-collagen VII.	Glycine	23-30	collagen type VII alpha 1 chain	Homo sapiens	64-70
24036283-1	2014	Glycine plays a key role in regulating inhibitory neurotransmission in the spinal cord and concentrations of glycine in the CNS are regulated by two subtypes of high affinity glycine transporters, GlyT1 and GlyT2.	Glycine	0-7	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	207-212
24036283-1	2014	Glycine plays a key role in regulating inhibitory neurotransmission in the spinal cord and concentrations of glycine in the CNS are regulated by two subtypes of high affinity glycine transporters, GlyT1 and GlyT2.	Glycine	109-116	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	207-212
24797328-6	2014	Hippocampal levels of glycine were decreased in sarcosine-treated animals, which was associated with a reduction of [(3)H] glycine uptake and a decrease in glycine transporter expression (GlyT-1 and GlyT-2).	Glycine	22-29	solute carrier family 6 member 9	Rattus norvegicus	188-194
24755469-4	2014	Subsequent functional assays identified SHMT2, a key enzyme in the serine/glycine synthesis pathway, as necessary for tumor cell survival but insufficient for transformation.	Glycine	74-81	serine hydroxymethyltransferase 2	Homo sapiens	40-45
24483321-0	2014	A new unstable variant of the fetal hemoglobin HBG2 gene: Hb F-Turritana [(G) gamma64(E8)Gly Asp, HBG2:c.194G&gt;A] found in cis to the Hb F-Sardinia gene [(A) gamma(E19)Ile Thr, HBG1:c.227T&gt;C].	Glycine	89-92	hemoglobin subunit gamma 2	Homo sapiens	47-51
24483321-3	2014	After HBG2 gene sequencing, the G to A transversion at codon 64, position eight of the E helix, was found, which corresponds to the Asp for Gly amino acid substitution.	Glycine	140-143	hemoglobin subunit gamma 2	Homo sapiens	6-10
24989301-2	2014	The binding ability of alpha-N-acetylgalactosaminidase with RBC in different reaction buffer such as alanine solution, glycine solution, normal saline (0.9% NaCl), PBS, PCS was detected by Western blot.	Glycine	119-126	RNA, 7SL, cytoplasmic 263, pseudogene	Homo sapiens	60-63
24989301-3	2014	The results showed that the efficiency of A to O conversion in alanine solution was similar to that in glycine solution, and Western blot confirmed that most of enzymes blinded with RBC in glycine or alanine solution, but few enzymes blinded with RBC in PBS, PCS or normal saline.	Glycine	189-196	RNA, 7SL, cytoplasmic 263, pseudogene	Homo sapiens	182-185
24989301-4	2014	The evidences indicated that binding of enzyme with RBC was a key element for A to O blood group conversion, while the binding ability of alpha-N-acetylgalactosaminidase with RBC in alanine or glycine solution was similar.	Glycine	193-200	RNA, 7SL, cytoplasmic 263, pseudogene	Homo sapiens	52-55
24989301-4	2014	The evidences indicated that binding of enzyme with RBC was a key element for A to O blood group conversion, while the binding ability of alpha-N-acetylgalactosaminidase with RBC in alanine or glycine solution was similar.	Glycine	193-200	RNA, 7SL, cytoplasmic 263, pseudogene	Homo sapiens	175-178
24658121-3	2014	Conjugation of PE to Atg8 requires processing of the C-terminal conserved glycine residue in Atg8 by the Atg4 cysteine protease.	Glycine	74-81	UbiA prenyltransferase family protein	Arabidopsis thaliana	105-109
24294904-5	2014	A biochemical study using truncated proteins lacking the defined functional domains of PARP1 showed that the tryptophan-glycine-arginine-rich (WGR) domain of PARP1 was critical for Salidroside binding and subsequent PARP1 activation under oxidative stress.	Glycine	120-127	poly (ADP-ribose) polymerase family, member 1	Mus musculus	87-92
24294904-5	2014	A biochemical study using truncated proteins lacking the defined functional domains of PARP1 showed that the tryptophan-glycine-arginine-rich (WGR) domain of PARP1 was critical for Salidroside binding and subsequent PARP1 activation under oxidative stress.	Glycine	120-127	poly (ADP-ribose) polymerase family, member 1	Mus musculus	158-163
24294904-5	2014	A biochemical study using truncated proteins lacking the defined functional domains of PARP1 showed that the tryptophan-glycine-arginine-rich (WGR) domain of PARP1 was critical for Salidroside binding and subsequent PARP1 activation under oxidative stress.	Glycine	120-127	poly (ADP-ribose) polymerase family, member 1	Mus musculus	158-163
24576490-2	2014	This study investigated the effects of physiologically relevant concentrations of Abeta (1 pM-100 nM), fragment 25-35, on glycine-mediated membrane current in acutely isolated rat hippocampal pyramidal neurons using whole-cell patch-clamp technique.	Glycine	122-129	amyloid beta precursor protein	Rattus norvegicus	82-87
24576490-3	2014	We have found that short (600 ms) co-application of glycine with Abeta caused reversible dose-dependent and voltage-independent acceleration of desensitization of glycine current.	Glycine	52-59	amyloid beta precursor protein	Rattus norvegicus	65-70
24576490-3	2014	We have found that short (600 ms) co-application of glycine with Abeta caused reversible dose-dependent and voltage-independent acceleration of desensitization of glycine current.	Glycine	163-170	amyloid beta precursor protein	Rattus norvegicus	65-70
24576490-8	2014	When Abeta was added to bath solution, besides acceleration of desensitization, it caused reversible dose-dependent reduction of glycine current peak amplitude.	Glycine	129-136	amyloid beta precursor protein	Rattus norvegicus	5-10
24576490-9	2014	These results demonstrate that physiological (picomolar) concentrations of Abeta reversibly augment the desensitization of glycine current, probably by binding to external sites on homomeric glycine receptors.	Glycine	123-130	amyloid beta precursor protein	Rattus norvegicus	75-80
24576490-10	2014	Furthermore, Abeta can suppress the peak amplitude of glycine current, but this effect develops slowly and may be mediated through some intracellular machinery.	Glycine	54-61	amyloid beta precursor protein	Rattus norvegicus	13-18
23417771-3	2014	We have generated a stable LMO4-DEAF-1 complex comprising the C-terminal LIM domain of LMO4 and an intrinsically disordered LMO4-interaction domain from DEAF-1 tethered by a glycine/serine linker.	Glycine	174-181	LIM domain only 4	Homo sapiens	27-31
23417771-3	2014	We have generated a stable LMO4-DEAF-1 complex comprising the C-terminal LIM domain of LMO4 and an intrinsically disordered LMO4-interaction domain from DEAF-1 tethered by a glycine/serine linker.	Glycine	174-181	DEAF1 transcription factor	Homo sapiens	32-38
23417771-3	2014	We have generated a stable LMO4-DEAF-1 complex comprising the C-terminal LIM domain of LMO4 and an intrinsically disordered LMO4-interaction domain from DEAF-1 tethered by a glycine/serine linker.	Glycine	174-181	DEAF1 transcription factor	Homo sapiens	153-159
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	195-198	thioredoxin reductase 1	Homo sapiens	45-50
24407164-1	2014	The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian selenocysteine (Sec)-containing flavoenzymes with a unique C-terminal -Gly-Cys-Sec-Gly active site.	Glycine	207-210	thioredoxin reductase 1	Homo sapiens	45-50
24273061-1	2014	Glycine GlyT2 transporters are localized on glycine-storing nerve endings.	Glycine	44-51	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	8-13
24273061-3	2014	Glycine was reported to be costored with gamma-aminobutyric acid (GABA) in cerebellar interneurons that may coexpress glycine and GABA transporters, and this is confirmed here by confocal microscopy analysis showing coexpression of GAT1 and GlyT2 transporters on microtubule-associated protein-2-positive synaptosomes.	Glycine	0-7	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	241-246
24273061-3	2014	Glycine was reported to be costored with gamma-aminobutyric acid (GABA) in cerebellar interneurons that may coexpress glycine and GABA transporters, and this is confirmed here by confocal microscopy analysis showing coexpression of GAT1 and GlyT2 transporters on microtubule-associated protein-2-positive synaptosomes.	Glycine	0-7	microtubule associated protein 2	Homo sapiens	263-295
24623205-4	2014	However, we found that participants older than 67 years who carried a combination of eNOS (Asp/Asp) genotype and ADRB2 glycine (Gly) allele were at a higher risk of having hypertension (p=0.029).	Glycine	119-126	adrenoceptor beta 2	Homo sapiens	113-118
24623205-4	2014	However, we found that participants older than 67 years who carried a combination of eNOS (Asp/Asp) genotype and ADRB2 glycine (Gly) allele were at a higher risk of having hypertension (p=0.029).	Glycine	128-131	adrenoceptor beta 2	Homo sapiens	113-118
24623205-5	2014	CONCLUSION: Our findings offer an opportunity for prediction of hypertension in elderly Lebanese individuals that carry a genetic combination of Asp/Asp genotype and Gly allele in eNOS and ADRB2 genes.	Glycine	166-169	adrenoceptor beta 2	Homo sapiens	189-194
24467211-6	2014	This study defines the role of H-protein in GLDC-catalyzed glycine decarboxylation.	Glycine	59-66	myosin binding protein H	Homo sapiens	31-40
24467211-9	2014	(3) The physiological product of glycine decarboxylation is H-protein-S-aminomethyl dihydrolipoyllysine and not methylamine (in the absence of H-protein, the aminomethyl moiety remains as a quinonoid adduct).	Glycine	33-40	myosin binding protein H	Homo sapiens	60-69
24974180-2	2014	GGT is a cell surface enzyme that hydrolyzes the gamma-glutamyl bond of extracellular reduced and oxidized glutathione, initiating their cleavage into glutamate, cysteine (cystine), and glycine.	Glycine	186-193	inactive glutathione hydrolase 2	Homo sapiens	0-3
25309911-4	2014	A virtual glycine scan revealed the contributions of individual residues to the energy of binding of 1-methylenesulfamide-1,2-dicarba-closo-dodecaborane to CAII and CAIX, respectively.	Glycine	10-17	carbonic anhydrase 2	Homo sapiens	156-160
24323194-3	2014	In order to investigate the effects of the mutations in ace1"s characteristic sites on pesticide resistance, we generated mutations for three amino acids using site-directed mutagenesis, which were Ala(GCG)303Ser(TCG), Gly(GGA)329Ala(GCA) and Leu (TCT)554Ser(TTC).	Glycine	219-222	acetylcholinesterase type 1	Bombyx mori	56-60
24154564-3	2013	Indeed, it is well established that alphavbeta3 integrin plays a key role in tumor angiogenesis acting like a receptor for the extracellular matrix proteins like vitronectin, fibronectin through the arginine-glycine-aspartic acid (RGD) sequence.	Glycine	208-215	vitronectin	Homo sapiens	162-173
24021960-7	2013	An interaction between the Val/Val genotype of the BDNF Val66Met and Gly/Gly polymorphism of the DRD3 Ser9Gly was found in BPII(+AD), but not in BP-II not comorbid with AD (BPI(-AD)) compared with healthy Controls.	Glycine	69-72	brain derived neurotrophic factor	Homo sapiens	51-55
24021960-10	2013	Because the Val/Val genotype of the BDNF Val66Met polymorphism, rather than the other two polymorphisms, has been associated with anxiety, it seems to affect BP-I comorbid with AD without the involvement of the DRD3 Seg9Gly polymorphism, but may modify the involvement of DRD3 Gly/Gly in BP-II comorbid with AD.	Glycine	220-223	brain derived neurotrophic factor	Homo sapiens	36-40
24021960-10	2013	Because the Val/Val genotype of the BDNF Val66Met polymorphism, rather than the other two polymorphisms, has been associated with anxiety, it seems to affect BP-I comorbid with AD without the involvement of the DRD3 Seg9Gly polymorphism, but may modify the involvement of DRD3 Gly/Gly in BP-II comorbid with AD.	Glycine	277-280	brain derived neurotrophic factor	Homo sapiens	36-40
24389431-8	2013	Overall, growth of NSCLC cell lines that carry a glycine to cystine KRAS mutation were more sensitive to RAL depletion than those with wild-type KRAS.	Glycine	49-56	KRAS proto-oncogene, GTPase	Homo sapiens	68-72
24389431-8	2013	Overall, growth of NSCLC cell lines that carry a glycine to cystine KRAS mutation were more sensitive to RAL depletion than those with wild-type KRAS.	Glycine	49-56	RAS like proto-oncogene A	Homo sapiens	105-108
24389431-11	2013	Simultaneously targeting RAL may provide a novel therapeutic approach in NSCLC patients harboring glycine to cystine KRAS mutations.	Glycine	98-105	RAS like proto-oncogene A	Homo sapiens	25-28
23849768-4	2013	Among the tested patients, 76.09% of patients had wt-KRAS genotype and 23.91% were KRAS mutants and the majority of mutations would result in an amino acid substitution of glycine by aspartic acid (68.2%) The predominant mutations are G&gt;A transitions and G&gt;T transversions.	Glycine	172-179	KRAS proto-oncogene, GTPase	Homo sapiens	83-87
24072682-9	2013	H(+):Gly-Sar absorption was completely inhibited by cephalexin (a competitive inhibitor of PepT1) and was activated by GIP.	Glycine	5-8	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	91-96
24225037-8	2013	In HA mice, we observed the upregulation of genes involved in neurotransmitter transport, the termination of GABA and glycine activity (Slc6a11, Slc6a9), glutamate uptake (Slc17a6), and the downregulation of neuropeptide Y (Npy) and corticotropin releasing hormone-binding protein (Crhbp).	Glycine	118-125	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	Mus musculus	136-143
24121337-2	2013	The crystal structure of the MK2-TEI-I01800 complex has been reported; its Gly-rich loop was found to form an alpha-helix, not a beta-sheet as has been observed for other Ser/Thr kinases.	Glycine	75-78	MAPK activated protein kinase 2	Homo sapiens	29-32
24121337-4	2013	Interestingly, the Gly-rich loop of CDK2 formed a beta-sheet that was different from that of MK2.	Glycine	19-22	MAPK activated protein kinase 2	Homo sapiens	93-96
24121337-5	2013	In MK2, TEI-I01800 changed the secondary structure of the Gly-rich loop from a beta-sheet to an alpha-helix by collision between Leu70 and a p-ethoxyphenyl group at the 7-position and bound to MK2.	Glycine	58-61	MAPK activated protein kinase 2	Homo sapiens	3-6
24121337-5	2013	In MK2, TEI-I01800 changed the secondary structure of the Gly-rich loop from a beta-sheet to an alpha-helix by collision between Leu70 and a p-ethoxyphenyl group at the 7-position and bound to MK2.	Glycine	58-61	MAPK activated protein kinase 2	Homo sapiens	193-196
23765399-2	2013	METHODS: Functionalized SWNTs with polymerised polymeric poly(ethylene imine) was linked NGR (Asn-Gly-Arg) tumor-targeting peptide by DSPE-PEG2000-Maleimide via the maleimide group and sulfhydryl group of cysteine, in the end, doxorubicin (DOX) was attached to SWNT-PEI to obtain a SWNT-PEI/DOX/NGR delivery system.	Glycine	98-101	reticulon 4 receptor	Homo sapiens	89-92
23765399-2	2013	METHODS: Functionalized SWNTs with polymerised polymeric poly(ethylene imine) was linked NGR (Asn-Gly-Arg) tumor-targeting peptide by DSPE-PEG2000-Maleimide via the maleimide group and sulfhydryl group of cysteine, in the end, doxorubicin (DOX) was attached to SWNT-PEI to obtain a SWNT-PEI/DOX/NGR delivery system.	Glycine	98-101	reticulon 4 receptor	Homo sapiens	295-298
24144057-7	2013	G6PD activity and SNO-Hb levels increased in the glycine-treated male group.	Glycine	49-56	glucose-6-phosphate dehydrogenase	Homo sapiens	0-4
24040206-2	2013	After translation pro-LC3 is processed by Atg4 to expose C-terminal glycine residue for downstream conjugation reactions to accomplish the conversion of LC3-I to LC3-II.	Glycine	68-75	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	22-25
24040206-2	2013	After translation pro-LC3 is processed by Atg4 to expose C-terminal glycine residue for downstream conjugation reactions to accomplish the conversion of LC3-I to LC3-II.	Glycine	68-75	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	153-156
24040206-2	2013	After translation pro-LC3 is processed by Atg4 to expose C-terminal glycine residue for downstream conjugation reactions to accomplish the conversion of LC3-I to LC3-II.	Glycine	68-75	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	153-156
23792041-2	2013	We recently reported that synthetic biotinylated peptides having a Tyr-Lys-Asp-Gly sequence inhibit PAF-induced inflammation by directly binding to PAF.	Glycine	79-82	PCNA clamp associated factor	Rattus norvegicus	100-103
23792041-2	2013	We recently reported that synthetic biotinylated peptides having a Tyr-Lys-Asp-Gly sequence inhibit PAF-induced inflammation by directly binding to PAF.	Glycine	79-82	PCNA clamp associated factor	Rattus norvegicus	148-151
23941530-5	2013	We found that glycine treatment of wild-type NMDA receptors led to recruitment of the adaptor protein 2 (AP-2), and subsequent internalization after activating the receptors by NMDA plus glycine.	Glycine	14-21	transcription factor AP-2 alpha	Homo sapiens	86-103
23941530-5	2013	We found that glycine treatment of wild-type NMDA receptors led to recruitment of the adaptor protein 2 (AP-2), and subsequent internalization after activating the receptors by NMDA plus glycine.	Glycine	14-21	transcription factor AP-2 alpha	Homo sapiens	105-109
23648696-6	2013	Pcca(-/-)(A138T) mice have 2% of wild-type PCC activity, survive to adulthood, and have elevations in propionyl-carnitine, methylcitrate, glycine, alanine, lysine, ammonia, and markers associated with cardiomyopathy similar to those in patients with PA.	Glycine	138-145	propionyl-Coenzyme A carboxylase, alpha polypeptide	Mus musculus	0-4
23785733-5	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Mus musculus	31-42
23741768-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
23466629-5	2013	STX17 has a hairpin-type structure mediated by two transmembrane domains, each containing glycine zipper motifs.	Glycine	90-97	syntaxin 17	Homo sapiens	0-5
23523779-6	2013	Peptide 47 (Gly(1), Gly(4), Trp(33)-HwTx) demonstrated the largest potency increase on hNav1.7 (IC50 0.4 +- 0.1 nM).	Glycine	12-15	sodium voltage-gated channel alpha subunit 9	Homo sapiens	87-94
23523779-6	2013	Peptide 47 (Gly(1), Gly(4), Trp(33)-HwTx) demonstrated the largest potency increase on hNav1.7 (IC50 0.4 +- 0.1 nM).	Glycine	20-23	sodium voltage-gated channel alpha subunit 9	Homo sapiens	87-94
23700433-3	2013	Here, we report that mutation of the central glycine in the pore-lining second transmembrane segment (TM2) to proline in Kir6.2 causes KATP channel inactivation.	Glycine	45-52	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	121-127
23664361-5	2013	Here, we compare the structures of GltPh, a glutamate transporter homolog, and LeuT, a homolog of neurotransmitter transporters for the biogenic amines and inhibitory molecules GABA and glycine.	Glycine	186-193	Leucine transport, high	Homo sapiens	79-83
23474074-5	2013	Overexpression of mitochondrial serine hydroxymethyltransferase, the enzyme converting l-serine to glycine, assures an adequate supply of glycine to rapidly proliferating cancer cells.	Glycine	99-106	serine hydroxymethyltransferase 2	Homo sapiens	18-63
23474074-5	2013	Overexpression of mitochondrial serine hydroxymethyltransferase, the enzyme converting l-serine to glycine, assures an adequate supply of glycine to rapidly proliferating cancer cells.	Glycine	138-145	serine hydroxymethyltransferase 2	Homo sapiens	18-63
23474074-10	2013	Our hypothesis is that mitochondrial serine hydroxymethyltransferase is fundamental to sustain cancer metabolism since production of glycine fuels heme biosynthesis and therefore oxidative phosphorylation.	Glycine	133-140	serine hydroxymethyltransferase 2	Homo sapiens	23-68
23474074-11	2013	Respiration of cancer cells may then ultimately rely on endogenous glycine synthesis by mitochondrial serine hydroxymethyltransferase.	Glycine	67-74	serine hydroxymethyltransferase 2	Homo sapiens	88-133
23474074-15	2013	If the observed increase of glycine consumption in rapidly proliferating cancer cells has its basis in the need for heme biosynthesis, then mitochondrial serine hydroxymethyltransferase should be considered as a key target for the development of new chemotherapeutic agents.	Glycine	28-35	serine hydroxymethyltransferase 2	Homo sapiens	140-185
23426876-7	2013	Functional genomics of the BSO profile, however, identified differential expression of genes related to glycine metabolism and energy metabolism (TPI1).	Glycine	104-111	triosephosphate isomerase 1	Bos taurus	146-150
23373819-1	2013	A recent ion mobility-mass spectrometry (IM-MS) study of the nonapeptide bradykinin (BK, amino acid sequence Arg(1)-Pro(2)-Pro(3)-Gly(4)-Phe(5)-Ser(6)-Pro(7)-Phe(8)-Arg(9)) found evidence for 10 populations of conformations that depend upon the solution composition [J.	Glycine	130-133	pyrroline-5-carboxylate reductase 1	Homo sapiens	123-128
24372240-7	2013	The protein-protein docking showed that the aminoacid residues of NS3 which were interacting with NRBP were found to be Ala 325, Asp 324, Phe 326, Asp 335, Glu 336, Glu 328, Asp 485, Gln 478, Arg 459, Gly 446 and Leu 480.	Glycine	201-204	KRAS proto-oncogene, GTPase	Homo sapiens	66-69
24372240-7	2013	The protein-protein docking showed that the aminoacid residues of NS3 which were interacting with NRBP were found to be Ala 325, Asp 324, Phe 326, Asp 335, Glu 336, Glu 328, Asp 485, Gln 478, Arg 459, Gly 446 and Leu 480.	Glycine	201-204	nuclear receptor binding protein 1	Homo sapiens	98-102
22858580-7	2013	Analysis of the cgUbiquitin C-terminus by carboxypeptidase B treatment and comparison of the retention times revealed that cgUbiquitin lacks the terminal Gly-Gly doublet and ends in an C-terminal Arg residue which might be related to antimicrobial activity.	Glycine	154-157	ubiquitin-60S ribosomal protein L40	Crassostrea gigas	123-134
22858580-7	2013	Analysis of the cgUbiquitin C-terminus by carboxypeptidase B treatment and comparison of the retention times revealed that cgUbiquitin lacks the terminal Gly-Gly doublet and ends in an C-terminal Arg residue which might be related to antimicrobial activity.	Glycine	158-161	ubiquitin-60S ribosomal protein L40	Crassostrea gigas	123-134
23285494-13	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
22453054-3	2012	Our previously published study reported a novel proteoglycan PTP1B inhibitor, named Fudan-Yueyang-Ganoderma lucidum (FYGL) from G. lucidum, with a half-maximal inhibitory concentration (IC50) value of 5 12 (sem 0 05) mug/ml, a protein:polyglycan ratio of 17:77 and 78 % glucose in polysaccharide, and dominant amino acid residues of aspartic acid, glycine, glutamic acid, alanine, serine and threonine in protein.	Glycine	348-355	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	61-66
23233222-5	2012	We found that the peak current of NMDARs and Ca(2+) influx induced by high concentration of NMDA were reduced by treatment of glycine (0.03-10 mumol L(-1)) in a dose-dependent manner, and that the glycine-dependent inhibition of NMDAR responses, which were induced at 300 mumol L(-1) NMDA, was reversed by ZnCl(2) through the blocking of the NR2A subunit of NMDARs, but was less influenced by ifenprodil, a NR2B inhibitor.	Glycine	126-133	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	407-411
23233222-5	2012	We found that the peak current of NMDARs and Ca(2+) influx induced by high concentration of NMDA were reduced by treatment of glycine (0.03-10 mumol L(-1)) in a dose-dependent manner, and that the glycine-dependent inhibition of NMDAR responses, which were induced at 300 mumol L(-1) NMDA, was reversed by ZnCl(2) through the blocking of the NR2A subunit of NMDARs, but was less influenced by ifenprodil, a NR2B inhibitor.	Glycine	197-204	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	407-411
23232528-2	2012	METHODS: We constructed E.coli-L.lactis shuttle plasmid,  pMG36e-RFP/eGFP,  containing a L.lactis expression cassette with the cDNA of red fluorescent protein (RFP) gene and a eukaryotic expression cassette with the cDNA of enhanced green fluorescent protein (eGFP),  then electrotransformated it into L.lactis cells,  and co-cultured with 293T cells to evaluate the role of the system in the improvement of gene delivering efficiency after L.lactis cells were pretreated with glycine.	Glycine	477-484	tripartite motif containing 27	Homo sapiens	160-163
22899363-2	2012	Here, the results of variable-temperature (2) H NMR spectra are reported for hydrated elastin that has been enriched at the Halpha position in its abundant glycines.	Glycine	156-164	elastin	Homo sapiens	86-93
23152013-3	2012	However, pooled analysis of randomized controlled studies in Western countries in patients treated with cetuximab has suggested that patients with tumors showing the KRAS p. G13D mutation[a glycine(G)to aspartate(D)transition mutation] have longer overall survival and progression-free survival when compared to patients with other KRAS mutations.	Glycine	190-197	KRAS proto-oncogene, GTPase	Homo sapiens	166-170
23152013-3	2012	However, pooled analysis of randomized controlled studies in Western countries in patients treated with cetuximab has suggested that patients with tumors showing the KRAS p. G13D mutation[a glycine(G)to aspartate(D)transition mutation] have longer overall survival and progression-free survival when compared to patients with other KRAS mutations.	Glycine	190-197	KRAS proto-oncogene, GTPase	Homo sapiens	332-336
22341128-1	2012	BACKGROUND: Glycine is a major inhibitory neurotransmitter in the spinal cord, the concentration of which is regulated by two types of glycine transporters (GlyTs): GlyT1 and GlyT2.	Glycine	12-19	solute carrier family 6 member 9	Rattus norvegicus	165-170
22847422-2	2012	A distinctive structural feature of all collagen types is a unique triple-helical structure formed by tandem repeats of the consensus sequence Xaa-Yaa-Gly, in which Xaa and Yaa frequently are proline and hydroxyproline, respectively.	Glycine	151-154	accelerated autoimmunity and lymphoproliferation transposition	Mus musculus	147-150
22847422-2	2012	A distinctive structural feature of all collagen types is a unique triple-helical structure formed by tandem repeats of the consensus sequence Xaa-Yaa-Gly, in which Xaa and Yaa frequently are proline and hydroxyproline, respectively.	Glycine	151-154	accelerated autoimmunity and lymphoproliferation transposition	Mus musculus	173-176
22623767-6	2012	The green fluorescent protein-fused wild-type or C-terminal helical regions of BGLF4 associate with phenylalanine/glycine repeat-containing nucleoporins (Nups) in nuclear envelope fractionation.	Glycine	114-121	tegument serine/threonine protein kinase	Human gammaherpesvirus 4	79-84
23012891-3	2012	As a result, it was shown that there were significant relationships between SD (self-directedness) and 49Ser/Gly (rs1801252) in ADRB1, P (persistence) and 389Arg/Gly (rs1801253) in ADRB1, and ST (self-transcendence) and 27Gln/Glu (rs1042714) in ADRB2 overall.	Glycine	109-112	adrenoceptor beta 2	Homo sapiens	245-250
22543185-3	2012	The interaction between the C-terminal domain of EB1 and the CAP-Gly domains of the +TIP CLIP-170 depends on the last tyrosine residue of EB1.	Glycine	65-68	microtubule associated protein RP/EB family member 1	Homo sapiens	49-52
22543185-3	2012	The interaction between the C-terminal domain of EB1 and the CAP-Gly domains of the +TIP CLIP-170 depends on the last tyrosine residue of EB1.	Glycine	65-68	CAP-Gly domain containing linker protein 1	Homo sapiens	89-97
22543185-3	2012	The interaction between the C-terminal domain of EB1 and the CAP-Gly domains of the +TIP CLIP-170 depends on the last tyrosine residue of EB1.	Glycine	65-68	microtubule associated protein RP/EB family member 1	Homo sapiens	138-141
22543185-5	2012	Using an MS-based approach, we showed that the last 15 amino-acid residues of EB1, either free or immobilized on beads, bound recombinant CAP-Gly domains of CLIP-170.	Glycine	142-145	microtubule associated protein RP/EB family member 1	Homo sapiens	78-81
22543185-5	2012	Using an MS-based approach, we showed that the last 15 amino-acid residues of EB1, either free or immobilized on beads, bound recombinant CAP-Gly domains of CLIP-170.	Glycine	142-145	CAP-Gly domain containing linker protein 1	Homo sapiens	157-165
22543185-7	2012	Western blotting in combination with a label-free quantitative proteomic analysis revealed that the peptidic probe harboring the C-terminal tyrosine of EB1 effectively pulled-down proteins with CAP-Gly domains from endothelial cell extracts.	Glycine	198-201	microtubule associated protein RP/EB family member 1	Homo sapiens	152-155
22542656-2	2012	Inhibition of glycine transporter-1 (GlyT1) is expected to increase glycine, a co-agonist of the NMDA receptor and, consequently, to facilitate NMDA receptor function.	Glycine	14-21	solute carrier family 6 member 9	Rattus norvegicus	37-42
22675745-3	2004	Glycine metabolism is controlled by GlyT1 and glycine transporter 2 (GlyT2) (2).	Glycine	0-7	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	69-74
22649803-19	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
22649804-19	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
22328406-7	2012	Further analysis revealed that an N-terminal glycine (G2), which is a conserved myristoylation site among vertebrates, is also essential for trafficking of Nphp3 to the ciliary shaft.	Glycine	45-52	nephronophthisis 3 (adolescent)	Mus musculus	156-161
22457887-4	2004	Because the integrin alphavbeta3 binds with extracellular matrix proteins (e.g., vitronectin, fibronectin) through the exposed Arg-Gly-Asp tripeptide sequence, RGD-containing peptides have been intensively studied in the past decade as a vector for imaging alphavbeta3 expression (3, 4).	Glycine	131-134	integrin subunit alpha V	Homo sapiens	12-32
22101068-4	2012	This mutation results in an aspartic acid to glycine substitution in the TUBA1 protein.	Glycine	45-52	tubulin, alpha 1A	Mus musculus	73-78
22115535-11	2012	CONCLUSIONS: Arg16Gly polymorphism of ADRB2 was significantly associated with obesity in female adolescents, and those with the Gly/Gly genotype were associated with a lower possibility of obesity and lower BMI.	Glycine	18-21	adrenoceptor beta 2	Homo sapiens	38-43
22115535-11	2012	CONCLUSIONS: Arg16Gly polymorphism of ADRB2 was significantly associated with obesity in female adolescents, and those with the Gly/Gly genotype were associated with a lower possibility of obesity and lower BMI.	Glycine	128-131	adrenoceptor beta 2	Homo sapiens	38-43
21984386-7	2012	The more relaxed substrate specificity of N-acetylgalactosamine kinase, compared to galactokinase, can be explained by the greater flexibility of a glycine rich loop in the active site of the enzyme.	Glycine	148-155	galactokinase 2	Homo sapiens	42-97
22664242-2	2012	Of these, the radiolabeled Arg-Gly- Asp (RGD) peptide has been focused because it has high affinity and selectivity for integrin alpha(v)beta3.	Glycine	31-34	integrin subunit alpha V	Homo sapiens	120-142
22272823-3	2012	Peptide RGD sequence Arg-Gly-Asp targeted and combined to integrin alphavbeta3 which has been overexpressed on tumor endothelial cells and many different tumor cellsis a robust site for tumor angiogenesis molecular imaging and targeted therapy.	Glycine	25-28	integrin subunit alpha V	Homo sapiens	58-78
23072183-5	2012	We report identification of c.3064G&gt;A, GGT&gt;AGT, Gly1022Ser (Gly(844) --&gt; Ser844 in triple helix) in exon 43 of the COL1A1 gene in an 8-year-old girl with OI type III.	Glycine	54-57	collagen type I alpha 1 chain	Homo sapiens	124-130
23056045-0	2012	Arginine 16 Glycine Polymorphism in beta2-Adrenergic Receptor Gene is Associated with Obesity, Hyperlipidemia, Hyperleptinemia, and Insulin Resistance in Saudis.	Glycine	12-19	adrenoceptor beta 2	Homo sapiens	36-61
23430891-4	2012	The 677C T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene was analyzed by PCR.Case 1 presented severe hyperhomocysteinemia (81 mumol/L; control values &lt;10.8) 3 months after Gly/Arg therapy.	Glycine	198-201	methylenetetrahydrofolate reductase	Homo sapiens	31-66
23049703-8	2012	By introducing a short glycine-serine-linker between the fourth and fifth alpha helix of human IL-10 a stable monomeric form of IL-10 (hIL-10(mono)) was created that no longer multimerised and increased yield up to 20-fold.	Glycine	23-30	interleukin 10	Homo sapiens	95-102
23049703-8	2012	By introducing a short glycine-serine-linker between the fourth and fifth alpha helix of human IL-10 a stable monomeric form of IL-10 (hIL-10(mono)) was created that no longer multimerised and increased yield up to 20-fold.	Glycine	23-30	interleukin 10	Homo sapiens	95-100
23049703-8	2012	By introducing a short glycine-serine-linker between the fourth and fifth alpha helix of human IL-10 a stable monomeric form of IL-10 (hIL-10(mono)) was created that no longer multimerised and increased yield up to 20-fold.	Glycine	23-30	interleukin 10	Homo sapiens	135-141
22432029-1	2012	Localization of CAP-Gly proteins such as CLIP170 at microtubule+ends results from their dual interaction with alpha-tubulin and EB1 through their C-terminal amino acids -EEY.	Glycine	20-23	CAP-Gly domain containing linker protein 1	Homo sapiens	41-48
22432029-1	2012	Localization of CAP-Gly proteins such as CLIP170 at microtubule+ends results from their dual interaction with alpha-tubulin and EB1 through their C-terminal amino acids -EEY.	Glycine	20-23	microtubule associated protein RP/EB family member 1	Homo sapiens	128-131
22235309-11	2012	253-NT cells expressing CEACAM1-4S with both glycine to leucine and tyrosine to valine mutations displayed the growth-enhanced phenotype of tyrosine mutants.	Glycine	45-52	CEA cell adhesion molecule 1	Rattus norvegicus	24-31
22187309-11	2011	However, a TTR Gly-54 point mutation in the 2nd exon was detected in two patients and 1 unaffected family member (one of the patients" daughters).	Glycine	15-18	transthyretin	Homo sapiens	11-14
22187309-13	2011	CONCLUSION: This pedigree affected with familial vitreous amyloidosis was characterized by autosomal dominant inheritance; a TTR Gly-54 point mutation in the 2nd exon is presumed to be the cause.	Glycine	129-132	transthyretin	Homo sapiens	125-128
22187309-14	2011	This Gly-54 point mutation of the TTR gene is a novel mutation in vitreous amyloidosis.	Glycine	5-8	transthyretin	Homo sapiens	34-37
21820454-8	2011	Impeding GluA2/GRIP/PICK1 interaction facilitated the NMDA/glycine/(S)AMPA-induced release of [(3)H]D-ASP, while competing for GluA2/NSF interaction reduced it, indicating that NMDA receptor favours AMPA receptor insertion in synaptosomal plasmamembranes.	Glycine	59-66	glutamate receptor interacting protein 1	Mus musculus	15-19
21820454-8	2011	Impeding GluA2/GRIP/PICK1 interaction facilitated the NMDA/glycine/(S)AMPA-induced release of [(3)H]D-ASP, while competing for GluA2/NSF interaction reduced it, indicating that NMDA receptor favours AMPA receptor insertion in synaptosomal plasmamembranes.	Glycine	59-66	protein interacting with C kinase 1	Mus musculus	20-25
22048503-1	2011	BACKGROUND AND OBJECTIVES: Several polymorphisms of the beta2-adrenergic receptor (beta2-AR) gene have been identified, including the amino acid substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic acid (Glu) at codon 27.	Glycine	181-188	adrenoceptor beta 2	Homo sapiens	56-81
22048503-1	2011	BACKGROUND AND OBJECTIVES: Several polymorphisms of the beta2-adrenergic receptor (beta2-AR) gene have been identified, including the amino acid substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic acid (Glu) at codon 27.	Glycine	181-188	adrenoceptor beta 2	Homo sapiens	83-91
22048503-1	2011	BACKGROUND AND OBJECTIVES: Several polymorphisms of the beta2-adrenergic receptor (beta2-AR) gene have been identified, including the amino acid substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic acid (Glu) at codon 27.	Glycine	190-193	adrenoceptor beta 2	Homo sapiens	56-81
22048503-1	2011	BACKGROUND AND OBJECTIVES: Several polymorphisms of the beta2-adrenergic receptor (beta2-AR) gene have been identified, including the amino acid substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic acid (Glu) at codon 27.	Glycine	190-193	adrenoceptor beta 2	Homo sapiens	83-91
21987804-0	2011	Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91.	Glycine	99-106	ORAI calcium release-activated calcium modulator 1	Homo sapiens	13-18
21987804-0	2011	Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91.	Glycine	99-106	ORAI calcium release-activated calcium modulator 1	Homo sapiens	81-86
21509743-0	2011	Influence of amino acid specificities on the molecular and supramolecular organization of glycine-rich elastin-like polypeptides in water.	Glycine	90-97	elastin	Homo sapiens	103-110
21509743-4	2011	These sequences contain the repeat XxxGlyGlyZzzGly (Xxx, Zzz = Val, Leu) motif belonging to the hydrophobic glycine-rich domain of elastin and represent a simplified model from which to obtain information on molecular interactions functional to elastin itself.	Glycine	108-115	elastin	Homo sapiens	131-138
21762741-11	2011	Our results show that in the rat hippocampus the release of GLY is, at least in part, of neuronal origin and is modulated by the activation of both alpha7 and alpha4beta2 (low and high affinity) nAChR subtypes.	Glycine	60-63	cholinergic receptor nicotinic beta 1 subunit	Rattus norvegicus	195-200
21646357-5	2011	Cell surface expression of G50C and G50A was rescued upon MG132 treatment as well as cyclosporine A, but not by FK506 or bile acids, suggesting that Gly(50) is involved in hASBT folding.	Glycine	149-152	solute carrier family 10 member 2	Homo sapiens	172-177
21593734-0	2011	Role of glycine receptors in glycine-induced LTD in hippocampal CA1 pyramidal neurons.	Glycine	8-15	carbonic anhydrase 1	Homo sapiens	64-67
21593734-4	2011	We report here that relatively high levels of glycine achieved either by exogenous glycine application or by the elevation of endogenous glycine accumulation with an antagonist of the glycine transporter induced long-term depression (LTD) of excitatory postsynaptic currents (EPSCs) in hippocampal CA1 pyramidal neurons.	Glycine	46-53	carbonic anhydrase 1	Homo sapiens	298-301
21447361-3	2011	The cyclic RGD (Arg-Gly-Asp) peptide, a specific ligand with affinity for Integrin alpha(v)beta(3) was coupled to the distal end of the PEG on the PEG-LP (RGD-PEG-LP).	Glycine	20-23	integrin subunit alpha V	Homo sapiens	74-98
21321476-4	2011	In the case of the CBD103 gene, all brindle dogs were heterozygous for the G23del mutation (deletion of codon 23, encoding glycine), while all sesame and red dogs were homozygous for G23.	Glycine	123-130	beta-defensin 14	Canis lupus familiaris	19-25
21530555-2	2011	The concentration of glycine is controlled, among other factors, by the glycine transporter 1 (GlyT1).	Glycine	21-28	solute carrier family 6 member 9	Rattus norvegicus	72-93
21530555-2	2011	The concentration of glycine is controlled, among other factors, by the glycine transporter 1 (GlyT1).	Glycine	21-28	solute carrier family 6 member 9	Rattus norvegicus	95-100
21270425-1	2011	A naturally occurring mutation in follicle-stimulating hormone receptor (FSHR) gene has been reported: an amino acid change to glycine occurs at a conserved aspartic acid 550 (D550, D567, D6.30(567)).	Glycine	127-134	follicle stimulating hormone receptor	Homo sapiens	34-71
21270425-1	2011	A naturally occurring mutation in follicle-stimulating hormone receptor (FSHR) gene has been reported: an amino acid change to glycine occurs at a conserved aspartic acid 550 (D550, D567, D6.30(567)).	Glycine	127-134	follicle stimulating hormone receptor	Homo sapiens	73-77
21539457-0	2011	Glycine cleavage enzyme complex: molecular cloning and expression of the H-protein cDNA from cultured human skin fibroblasts.	Glycine	0-7	myosin binding protein H	Homo sapiens	73-82
21539457-1	2011	The human H-protein is one of four essential components (H-, L-, P-, and T-proteins) of the mammalian glycine cleavage enzyme complex and its function is involved in the pathogenesis and diagnosis of glycine encephalopathy.	Glycine	102-109	myosin binding protein H	Homo sapiens	10-19
21539457-1	2011	The human H-protein is one of four essential components (H-, L-, P-, and T-proteins) of the mammalian glycine cleavage enzyme complex and its function is involved in the pathogenesis and diagnosis of glycine encephalopathy.	Glycine	200-207	myosin binding protein H	Homo sapiens	10-19
21539457-2	2011	A transcript corresponding to the glycine cleavage H-protein functional gene was isolated from cultured human skin fibroblasts along with a transcript for a putative processed pseudogene on chromosome 2q33.3.	Glycine	34-41	myosin binding protein H	Homo sapiens	51-60
21539457-9	2011	The availability of copious amounts of human recombinant H-protein by using Pichia pastoris expression and affinity purification will facilitate the elucidation of the structure and function of the H-protein and its relationship to the P-, T-, and L-proteins in the glycine cleavage enzyme complex.	Glycine	266-273	myosin binding protein H	Homo sapiens	57-66
21539457-9	2011	The availability of copious amounts of human recombinant H-protein by using Pichia pastoris expression and affinity purification will facilitate the elucidation of the structure and function of the H-protein and its relationship to the P-, T-, and L-proteins in the glycine cleavage enzyme complex.	Glycine	266-273	myosin binding protein H	Homo sapiens	198-207
21595127-5	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Mus musculus	31-42
21595128-5	2004	Extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) contain a tripeptide sequence consisting of Arg-Gly-Asp (RGD), which binds to a variety of integrins, including alphavbeta3.	Glycine	127-130	vitronectin	Mus musculus	31-42
21393249-6	2011	Using affinity chromatography and mass spectrometry, we identify sarcosine dehydrogenase (SARDH), the enzyme that converts sarcosine to glycine, as a TMEFF2-interacting protein.	Glycine	136-143	sarcosine dehydrogenase	Homo sapiens	65-88
21393249-6	2011	Using affinity chromatography and mass spectrometry, we identify sarcosine dehydrogenase (SARDH), the enzyme that converts sarcosine to glycine, as a TMEFF2-interacting protein.	Glycine	136-143	sarcosine dehydrogenase	Homo sapiens	90-95
21547333-0	2011	In this issue: glycine substitution mutations in the COL7A1 gene: implications for inheritance of dystrophic epidermolysis bullosa - dominant vs. recessive.	Glycine	15-22	collagen type VII alpha 1 chain	Homo sapiens	53-59
21298412-1	2011	AIMS/HYPOTHESIS: Homozygosity for glycine at codon 16 (GlyGly) of the beta(2)-adrenergic receptor may alter receptor sensitivity upon chronic stimulation and has been implicated in the pathogenesis of hypoglycaemia unawareness.	Glycine	34-41	adrenoceptor beta 2	Homo sapiens	70-97
21454242-11	2011	The Arg52Gly mutation replaces the normal arginine residue (CGC) with a glycine residue (GGC) at position 52 of the resultant menin protein.	Glycine	72-79	gamma-glutamylcyclotransferase	Homo sapiens	89-92
21628128-4	2011	CDSN displays adhesive properties, mostly attributable to its N-terminal glycine-rich domain, and is sequentially proteolyzed as corneocytes migrate towards the skin surface prior to desquamation.	Glycine	73-80	corneodesmosin	Homo sapiens	0-4
21348870-5	2011	Accordingly, [(3)H]glycine was taken up during superfusion, while lowering the external concentration of Na(+), the monovalent cation co-transported with glycine by GlyT1, abrogated the NMDA-induced effect.	Glycine	19-26	solute carrier family 6 member 9	Rattus norvegicus	165-170
21348870-7	2011	It is proposed that GlyT1s coexist with NMDA autoreceptors on rat hippocampal glutamatergic terminals and that glycine taken up by GlyT1 may permit physiological activation of NMDA pre-synaptic autoreceptors.	Glycine	111-118	solute carrier family 6 member 9	Rattus norvegicus	131-136
21343309-6	2011	More precisely, we identified a glycine zipper motif in the transmembrane domain of EWI-2/EWI-2wint that is essential for the interaction with CD81.	Glycine	32-39	immunoglobulin superfamily member 8	Homo sapiens	84-89
21343309-6	2011	More precisely, we identified a glycine zipper motif in the transmembrane domain of EWI-2/EWI-2wint that is essential for the interaction with CD81.	Glycine	32-39	immunoglobulin superfamily member 8	Homo sapiens	90-95
21343309-6	2011	More precisely, we identified a glycine zipper motif in the transmembrane domain of EWI-2/EWI-2wint that is essential for the interaction with CD81.	Glycine	32-39	CD81 molecule	Homo sapiens	143-147
21491703-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
21491704-10	2004	A tumor cell targeting peptide, Gly-Ala-Cys-Leu-Arg-Ser-Gly-Arg-Gly-Cys-Gly (TCTP-1), was identified via phage display screening against MMP-9.	Glycine	32-35	matrix metallopeptidase 9	Homo sapiens	137-142
21491704-10	2004	A tumor cell targeting peptide, Gly-Ala-Cys-Leu-Arg-Ser-Gly-Arg-Gly-Cys-Gly (TCTP-1), was identified via phage display screening against MMP-9.	Glycine	56-59	matrix metallopeptidase 9	Homo sapiens	137-142
21491704-10	2004	A tumor cell targeting peptide, Gly-Ala-Cys-Leu-Arg-Ser-Gly-Arg-Gly-Cys-Gly (TCTP-1), was identified via phage display screening against MMP-9.	Glycine	56-59	matrix metallopeptidase 9	Homo sapiens	137-142
21427001-2	2011	We previously reported that forebrain embryonic zinc finger-like (FEZL) encoding a stretch of 12 glycines (p.Gly105[12]) instead of 13 glycines (p.Gly105[13]) is associated with a lower somatic cell score (SCS) in a family derived from Walkway Chief Mark.	Glycine	97-105	SCS	Bos taurus	206-209
21153865-6	2011	h[Gly(2)]GLP-2 pretreatment prevented the TNF-alpha/Act D-induced oxidative injury by a significant reduction in the intestinal injury, apoptotic index, expression of active caspase-3, lipid peroxidation and GSH levels, GPx and SOD activities; a markedly increase in cell proliferation, and CAT activity.	Glycine	2-5	caspase 3	Mus musculus	174-183
21262301-2	2011	Other Gly-extended and Ser(13)-phosphorylated PYY forms have been detected or predicted based upon known cellular processes of PYY synthesis and modification.	Glycine	6-9	peptide YY	Rattus norvegicus	46-49
21262301-2	2011	Other Gly-extended and Ser(13)-phosphorylated PYY forms have been detected or predicted based upon known cellular processes of PYY synthesis and modification.	Glycine	6-9	peptide YY	Rattus norvegicus	127-130
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	23-29	peptide YY	Rattus norvegicus	13-16
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	13-16
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	13-16
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	13-16
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21262301-6	2011	In contrast, PYY(1-36)-Gly-OH, PYY(3-36)-Gly-OH, Ser(13)(PO(3))-PYY(3-36)-Gly-OH, and Ser(13)(PO(3))-PYY(1-36)-Gly-OH had no effect on food intake at doses of 50 or 150 pmol/kg/min.	Glycine	41-47	peptide YY	Rattus norvegicus	31-34
21245148-2	2011	The mainly glial GLYT1 is the key regulator of the glycine levels in glycinergic and glutamatergic pathways, whereas the neuronal GLYT2 is involved in the recycling of synaptic glycine from the inhibitory synaptic cleft.	Glycine	51-58	solute carrier family 6 member 9	Rattus norvegicus	17-22
21245148-2	2011	The mainly glial GLYT1 is the key regulator of the glycine levels in glycinergic and glutamatergic pathways, whereas the neuronal GLYT2 is involved in the recycling of synaptic glycine from the inhibitory synaptic cleft.	Glycine	69-76	solute carrier family 6 member 9	Rattus norvegicus	17-22
20641300-6	2004	A tripeptide sequence consisting of Arg-Gly-Asp (RGD) was identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including alphavbeta3.	Glycine	40-43	vitronectin	Homo sapiens	131-142
21185309-4	2011	Here, we show that IDE cleaves Ub in a biphasic manner, first, by rapidly removing the two C-terminal glycines (k(cat)=2 s(-1)) followed by a slow cleavage between residues 72 and 73 (k(cat)=0.07 s(-1)), thereby producing the inactive 1-74 fragment of Ub (Ub1-74) and 1-72 fragment of Ub (Ub1-72).	Glycine	102-110	insulin degrading enzyme	Homo sapiens	19-22
21280133-3	2011	Five different BTK protein conformations are stabilized by the bound inhibitors, providing insights into the structural flexibility of the Gly-rich loop, helix C, the DFG sequence, and activation loop.	Glycine	139-142	Bruton tyrosine kinase	Homo sapiens	15-18
21249762-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	121-132
20560144-4	2011	For this, we prepared a series of peptides that contain a single substitution of Gly with L-Ala, D-Ala, beta-Ala, or sarcosine (Sar), at different positions in a host peptide (Pro-Hyp-Gly)(8) .	Glycine	81-84	sarcosine dehydrogenase	Homo sapiens	128-131
20725951-0	2011	Interruption of a 3(10)-helix by a single Gly residue in a poly-Aib motif: a crystallographic study.	Glycine	42-45	ANIB1	Homo sapiens	64-67
22008442-6	2011	We detected a new GLA missense mutation (G195V) in exon 4, resulting in a glycine-to-valine substitution.	Glycine	74-81	galactosidase alpha	Homo sapiens	18-21
21190592-1	2010	BACKGROUND: The vesicular GABA transporter (VGAT) loads GABA and glycine from the neuronal cytoplasm into synaptic vesicles.	Glycine	65-72	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	16-42
21190592-1	2010	BACKGROUND: The vesicular GABA transporter (VGAT) loads GABA and glycine from the neuronal cytoplasm into synaptic vesicles.	Glycine	65-72	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	44-48
21190592-3	2010	RESULTS: VGAT knockouts at embryonic day (E) 18.5 exhibited substantial increases in overall GABA and glycine, but not glutamate, contents in the forebrain.	Glycine	102-109	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	9-13
21190592-6	2010	CONCLUSION: VGAT is fundamental for the GABA- and/or glycine-mediated transmission that supports embryonic development.	Glycine	53-60	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	12-16
21204315-13	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (e.g., vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Homo sapiens	127-138
21049545-1	2010	UNLABELLED: Bile acid-CoA:amino acid N-acyltransferase (BAAT) conjugates bile salts to glycine or taurine, which is the final step in bile salt biosynthesis.	Glycine	87-94	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	12-54
21049545-1	2010	UNLABELLED: Bile acid-CoA:amino acid N-acyltransferase (BAAT) conjugates bile salts to glycine or taurine, which is the final step in bile salt biosynthesis.	Glycine	87-94	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	56-60
20725779-3	2010	N-methyl-D-aspartate (NMDA) receptor hypofunction in schizophrenia can be reversed by glycine transporter type-1 (GlyT-1) inhibitors, which regulate glycine concentrations at the vicinity of NMDA receptors.	Glycine	86-93	solute carrier family 6 member 9	Rattus norvegicus	114-120
20934468-5	2010	Here we fused the elastin derived peptide Ala-Pro-Gly-Val-Gly-Val (APGVGV) with the cell adhesive peptides, Pro-His-Ser-Arg-Asn (PHSRN) and Arg-Gly-Asp (RGD).	Glycine	50-53	elastin	Homo sapiens	18-25
21085509-3	2010	Previously, in our group, amino acid based amphiphiles i.e. Gly-Gly-His-EO2-Alk, a trimodular amphiphile (containing three domains: H-bond donor and acceptor/hydrophilic/hydrophobic domain, respectively) were reported to act as hydrogelators and that the gelation properties were related to hydrogen bonding, hydrophobic interactions and pi-pi stacking.	Glycine	64-67	ALK receptor tyrosine kinase	Homo sapiens	76-79
20635087-6	2010	Also supporting a key role for the FATC domain in the structure/function of Tra1, addition of a C-terminal glycine residue resulted in decreased association with Spt7 and Esa1, and loss of cellular viability.	Glycine	107-114	NuA4 histone acetyltransferase complex catalytic subunit ESA1	Saccharomyces cerevisiae S288C	171-175
20973643-7	2010	Gln-Gly cleavages are largely associated with PRP classes, while Tyr-Gly cleavages are related to histatin 1 and to the P-B peptide.	Glycine	69-72	histatin 1	Homo sapiens	98-108
20871037-9	2010	Gly(286), the mutation site from NAT2*4 to NAT2*7, was located near coenzyme A (CoA) in the boundary of the positive and negative fields.	Glycine	0-3	N-acetyltransferase 2	Homo sapiens	33-37
20871037-9	2010	Gly(286), the mutation site from NAT2*4 to NAT2*7, was located near coenzyme A (CoA) in the boundary of the positive and negative fields.	Glycine	0-3	N-acetyltransferase 2	Homo sapiens	43-47
20570056-7	2010	In addition, a myristate moiety linked to the N-terminal glycine of PreS1 appears critical for HBV infectivity.	Glycine	57-64	large envelope protein;middle envelope protein;small envelope protein	Hepatitis B virus	68-73
20662138-5	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3.	Glycine	25-28	vitronectin	Mus musculus	121-132
20471369-0	2010	Screening of novel dominant negative mutant actins using glycine targeted scanning identifies G146V actin that cooperatively inhibits cofilin binding.	Glycine	57-64	cofilin	Saccharomyces cerevisiae S288C	134-141
20303337-3	2010	In the present study we tested several glycine transporter 1 (GlyT1) inhibitors including NFPS, SSR 504734, Lu AA21279, Org 25935, SB-710622, GSK931145, as well as the glycine agonist d-serine, in the maximal electroshock threshold (MEST) test in the rat.	Glycine	39-46	solute carrier family 6 member 9	Rattus norvegicus	62-67
20150244-6	2010	Using wild-type (WT) and Pat-1(-) mice, Ussing chambers were employed to measure the short-circuit current (I(sc)) associated with Pept1-mediated glycyl-sarcosine (Gly-Sar) absorption.	Glycine	164-167	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	131-136
20441557-4	2010	Furthermore, this investigation reveals that three common codons, CGC (Arg), AGC (Ser), and GGC (Gly), are also critical in affecting codon usage bias.	Glycine	97-100	gamma-glutamylcyclotransferase	Homo sapiens	92-95
20237295-0	2010	Lysophosphatidylcholine increases neutrophil bactericidal activity by enhancement of azurophil granule-phagosome fusion via glycine.GlyR alpha 2/TRPM2/p38 MAPK signaling.	Glycine	124-131	transient receptor potential cation channel subfamily M member 2	Homo sapiens	145-150
20354225-2	2010	We found that NUAK1 interacts with several myosin phosphatases, including the myosin phosphatase targeting-1 (MYPT1)-protein phosphatase-1beta (PP1beta) complex, through conserved Gly-Ile-Leu-Lys motifs that are direct binding sites for PP1beta.	Glycine	180-183	NUAK family kinase 1	Homo sapiens	14-19
20407581-4	2010	In contrast, recombinant receptors composed of NR1 and the glycine binding NR3A and/or NR3B subunits lack glutamate binding sites and can be activated by glycine alone.	Glycine	154-161	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	87-91
20407581-8	2010	Whole-cell current-voltage relations of glycine currents recorded from NR1/NR3B and NR1/NR3A/NR3B expressing oocytes were found to be linear under our recording conditions.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	75-79
20407581-8	2010	Whole-cell current-voltage relations of glycine currents recorded from NR1/NR3B and NR1/NR3A/NR3B expressing oocytes were found to be linear under our recording conditions.	Glycine	40-47	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	93-97
20036251-1	2010	N-Myristoyltransferase (NMT) catalyses the attachment of the 14-carbon saturated fatty acid, myristate, to the amino-terminal glycine residue of a subset of eukaryotic proteins that function in multiple cellular processes, including vesicular protein trafficking and signal transduction.	Glycine	126-133	N-myristoyltransferase	Leishmania donovani	0-22
20036251-1	2010	N-Myristoyltransferase (NMT) catalyses the attachment of the 14-carbon saturated fatty acid, myristate, to the amino-terminal glycine residue of a subset of eukaryotic proteins that function in multiple cellular processes, including vesicular protein trafficking and signal transduction.	Glycine	126-133	N-myristoyltransferase	Leishmania donovani	24-27
20391780-6	2010	Mutation (Ser917 --&gt; Gly) in nonstructural protein NS1 results in the substitution of hydrophilic amino acid, specific to highly virulent strains, by the hydrophobic one.	Glycine	24-27	influenza virus NS1A binding protein	Homo sapiens	54-57
20032456-5	2010	The mutated glycine is in the pore-lining transmembrane helix of Kir6.2; an equivalent glycine in other potassium channels has been proposed to serve as a hinge to allow helix bending during gating.	Glycine	12-19	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	65-71
20133743-0	2010	Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains.	Glycine	96-103	kelch-like ECH-associated protein 1	Mus musculus	0-5
19929855-9	2010	Moreover, Gly85 and Gly87, within a glycine-rich domain as part of a potential flexible loop, were found to be required for Alg11 function.	Glycine	36-43	alpha-1,2-mannosyltransferase ALG11	Saccharomyces cerevisiae S288C	124-129
19913027-4	2010	However, the observation that CLIP-170 has two CAP-Gly (cytoskeleton-associated protein glycine-rich) motifs and multiple serine-rich regions suggests that a single CLIP-170 molecule has multiple tubulin binding sites, and that these sites might bind to multiple parts of the tubulin dimer.	Glycine	51-54	CAP-Gly domain containing linker protein 1	Homo sapiens	30-38
19913027-4	2010	However, the observation that CLIP-170 has two CAP-Gly (cytoskeleton-associated protein glycine-rich) motifs and multiple serine-rich regions suggests that a single CLIP-170 molecule has multiple tubulin binding sites, and that these sites might bind to multiple parts of the tubulin dimer.	Glycine	88-95	CAP-Gly domain containing linker protein 1	Homo sapiens	30-38
20045321-2	2010	Synthesis and SAR follow-up of a series of octahydro-cyclopenta[c]pyrrole derivatives afforded potent in vitro inhibition of GlyT1 as well as in vivo activity in elevating CSF glycine.	Glycine	176-183	sarcosine dehydrogenase	Homo sapiens	14-17
20233000-6	2010	RESULTS: Glycine pretreatment markedly decreased transaminase release (AST, 12 hr: glycine 1292 +/- 192 U/L, control 2311 +/- 556 U/L, p &lt; .05; ALT, 12 hr: glycine 1013 +/- 278 U/L, control 2038 +/- 500 U/L, p &lt; .05), serum ALP activity and serum bilirubin levels (p &lt; .05).	Glycine	9-16	ATHS	Homo sapiens	230-233
19890265-6	2010	The abundance of the small neutral amino acids, serine, alanine, and glycine, was lower and/or was poorly induced after methamphetamine administration in the frontoparietal cortex and striatum of FosB(-/-) mice.	Glycine	69-76	FBJ osteosarcoma oncogene B	Mus musculus	196-200
20057052-0	2010	Structural analysis of an MK2-inhibitor complex: insight into the regulation of the secondary structure of the Gly-rich loop by TEI-I01800.	Glycine	111-114	MAPK activated protein kinase 2	Homo sapiens	26-29
20057052-3	2010	The MK2 structure in the MK2-TEI-I01800 complex is composed of two domains, as observed for other Ser/Thr kinases; however, the Gly-rich loop in the N-terminal domain forms an alpha-helix structure and not a beta-sheet.	Glycine	128-131	MAPK activated protein kinase 2	Homo sapiens	4-7
20057052-3	2010	The MK2 structure in the MK2-TEI-I01800 complex is composed of two domains, as observed for other Ser/Thr kinases; however, the Gly-rich loop in the N-terminal domain forms an alpha-helix structure and not a beta-sheet.	Glycine	128-131	MAPK activated protein kinase 2	Homo sapiens	25-28
20057052-6	2010	The MK2-TEI-I01800 complex structure is the first active MK2 with an alpha-helical Gly-rich loop and TEI-I01800 regulates the secondary structure of the Gly-rich loop.	Glycine	83-86	MAPK activated protein kinase 2	Homo sapiens	4-7
20057052-6	2010	The MK2-TEI-I01800 complex structure is the first active MK2 with an alpha-helical Gly-rich loop and TEI-I01800 regulates the secondary structure of the Gly-rich loop.	Glycine	83-86	MAPK activated protein kinase 2	Homo sapiens	57-60
20057052-6	2010	The MK2-TEI-I01800 complex structure is the first active MK2 with an alpha-helical Gly-rich loop and TEI-I01800 regulates the secondary structure of the Gly-rich loop.	Glycine	153-156	MAPK activated protein kinase 2	Homo sapiens	4-7
20057052-6	2010	The MK2-TEI-I01800 complex structure is the first active MK2 with an alpha-helical Gly-rich loop and TEI-I01800 regulates the secondary structure of the Gly-rich loop.	Glycine	153-156	MAPK activated protein kinase 2	Homo sapiens	57-60
19882657-0	2010	Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin.	Glycine	117-120	integrin subunit alpha V	Homo sapiens	28-51
19882657-0	2010	Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin.	Glycine	117-120	vitronectin	Homo sapiens	52-63
20641584-4	2004	The peptide sequence Arg-Gly-Asp (RGD) has been identified as a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins, including alphavbeta3 and alphavbeta5.	Glycine	25-28	vitronectin	Homo sapiens	121-132
20003375-4	2009	METHODS: Real-time PCR and sequence analysis were utilized to identify Ha- and Ki-ras mutation (Gly -&gt; Val).	Glycine	96-99	KRAS proto-oncogene, GTPase	Homo sapiens	79-85
20041218-11	2009	We found a G&lt;--&gt;A transition at position 1448, causing a Gly to Glu substitution (Gly483Glu) in the highly conserved N-terminal RCC1-like domain of the HERC1 protein.	Glycine	63-66	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	Mus musculus	158-163
19932356-1	2009	BACKGROUND: Some studies suggest that patients with asthma who are homozygous for arginine at the 16th amino acid position of the beta2-adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting beta2 agonists and inhaled corticosteroids than do those homozygous for glycine (B16 Gly/Gly).	Glycine	286-293	adrenoceptor beta 2	Homo sapiens	130-155
19932356-1	2009	BACKGROUND: Some studies suggest that patients with asthma who are homozygous for arginine at the 16th amino acid position of the beta2-adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting beta2 agonists and inhaled corticosteroids than do those homozygous for glycine (B16 Gly/Gly).	Glycine	299-302	adrenoceptor beta 2	Homo sapiens	130-155
19932356-1	2009	BACKGROUND: Some studies suggest that patients with asthma who are homozygous for arginine at the 16th amino acid position of the beta2-adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting beta2 agonists and inhaled corticosteroids than do those homozygous for glycine (B16 Gly/Gly).	Glycine	303-306	adrenoceptor beta 2	Homo sapiens	130-155
19796639-0	2009	A glycine hinge for tRNA-dependent translocation of editing substrates to prevent errors by leucyl-tRNA synthetase.	Glycine	2-9	leucyl-tRNA synthetase 1	Homo sapiens	92-114
19796639-4	2009	A glycine within a flexible beta-strand that links the aminoacylation and editing domains of LeuRS was determined to be important to tRNA translocation.	Glycine	2-9	leucyl-tRNA synthetase 1	Homo sapiens	93-98
19696402-6	2009	Molar ratios for FIXpep, FXpep, and F1+2 to FVIIa were constant in Ser/Ser and Ser/Gly but tended to be higher in Gly/Gly, reaching statistical significance for FIXpep:FVIIa (P=0.04).	Glycine	83-86	coagulation factor XII	Homo sapiens	36-40
19571258-5	2009	Bovine milk SPP1, ovine uterine SPP1, and recombinant wild-type, but not mutated, rat SPP1 promoted dose- and cation-dependent attachment of porcine trophectoderm and uterine luminal epithelial cells, which was markedly reduced in the presence of a linear Arg-Gly-Asp integrin-blocking peptide.	Glycine	260-263	secreted phosphoprotein 1	Bos taurus	12-16
19659572-4	2009	Here, we demonstrate that FMRP is required for glycine induced LTP (Gly-LTP) in the CA1 of hippocampus.	Glycine	47-54	fragile X messenger ribonucleoprotein 1	Mus musculus	26-30
19659572-4	2009	Here, we demonstrate that FMRP is required for glycine induced LTP (Gly-LTP) in the CA1 of hippocampus.	Glycine	68-71	fragile X messenger ribonucleoprotein 1	Mus musculus	26-30
20641306-4	2004	GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2), which is necessary for receptor binding and signal transduction (5, 6).	Glycine	62-65	gastrin releasing peptide	Homo sapiens	0-3
19707686-1	2009	Previously, downsizing of a 14-residue peptidic CXCR4 antagonist has led to the development of a highly potent CXCR4 antagonist [cyclo(-d-Tyr(1)-Arg(2)-Arg(3)-Nal(4)-Gly(5)-)].	Glycine	166-169	C-X-C motif chemokine receptor 4	Homo sapiens	48-53
19707686-1	2009	Previously, downsizing of a 14-residue peptidic CXCR4 antagonist has led to the development of a highly potent CXCR4 antagonist [cyclo(-d-Tyr(1)-Arg(2)-Arg(3)-Nal(4)-Gly(5)-)].	Glycine	166-169	C-X-C motif chemokine receptor 4	Homo sapiens	111-116
19130907-3	2009	The "hinge 2" site of GroEL contains three glycine residues, Gly192, Gly374, and Gly375, connecting the apical domain and the intermediate domain.	Glycine	43-50	heat shock protein family D (Hsp60) member 1	Homo sapiens	22-27
19360404-1	2009	PURPOSE: Radiolabeled Arg-Gly-Asp (RGD) and bombesin (BBN) peptide analogs have been extensively investigated for the imaging of tumor integrin alpha(v)beta(3) and gastrin-releasing peptide receptor (GRPR) expression, respectively.	Glycine	26-29	integrin subunit alpha V	Homo sapiens	135-159
19570983-4	2009	LIP2 and LIP5 are required for lipoylation of all three mitochondrial target proteins: Lat1 and Kgd2, the respective E2 subunits of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, and Gcv3, the H protein of the glycine cleavage enzyme.	Glycine	225-232	alpha-ketoglutarate dehydrogenase KGD2	Saccharomyces cerevisiae S288C	96-100
19570983-7	2009	We show that lipoylated Gcv3, and not glycine cleavage activity per se, is responsible for this function.	Glycine	38-45	glycine decarboxylase subunit H	Saccharomyces cerevisiae S288C	24-28
19494039-4	2009	Aurora A residue glycine 198 (G198), mutated to asparagine to mimic the aligned asparagine 142 (N142) of Aurora B, causes Aurora A to bind the Aurora B binding partner INCENP but not the Aurora A binding partner TPX2.	Glycine	17-24	aurora kinase B	Homo sapiens	105-113
19494039-4	2009	Aurora A residue glycine 198 (G198), mutated to asparagine to mimic the aligned asparagine 142 (N142) of Aurora B, causes Aurora A to bind the Aurora B binding partner INCENP but not the Aurora A binding partner TPX2.	Glycine	17-24	aurora kinase B	Homo sapiens	143-151
19494039-4	2009	Aurora A residue glycine 198 (G198), mutated to asparagine to mimic the aligned asparagine 142 (N142) of Aurora B, causes Aurora A to bind the Aurora B binding partner INCENP but not the Aurora A binding partner TPX2.	Glycine	17-24	TPX2 microtubule nucleation factor	Homo sapiens	212-216
19373110-8	2009	RESULTS: The odds ratio for the presence of hypertension in individuals having the Gly/Gly genotype of ADRB2 compared with those having the other genotypes (Arg/Arg and Arg/Gly) was 2.87.	Glycine	83-86	adrenoceptor beta 2	Homo sapiens	103-108
19373110-8	2009	RESULTS: The odds ratio for the presence of hypertension in individuals having the Gly/Gly genotype of ADRB2 compared with those having the other genotypes (Arg/Arg and Arg/Gly) was 2.87.	Glycine	87-90	adrenoceptor beta 2	Homo sapiens	103-108
19373110-8	2009	RESULTS: The odds ratio for the presence of hypertension in individuals having the Gly/Gly genotype of ADRB2 compared with those having the other genotypes (Arg/Arg and Arg/Gly) was 2.87.	Glycine	87-90	adrenoceptor beta 2	Homo sapiens	103-108
19373110-10	2009	Interestingly, the odds ratio was 7.64 for individuals having a combination of the Gly/Gly genotype of ADRB2 and Glu/Glu genotype of NOS3 when compared with those having a combination of Arg/Arg and Arg/Gly genotypes of ADRB2 and Asp/Asp and Asp/Glu genotypes of NOS3.	Glycine	83-86	adrenoceptor beta 2	Homo sapiens	103-108
19373110-10	2009	Interestingly, the odds ratio was 7.64 for individuals having a combination of the Gly/Gly genotype of ADRB2 and Glu/Glu genotype of NOS3 when compared with those having a combination of Arg/Arg and Arg/Gly genotypes of ADRB2 and Asp/Asp and Asp/Glu genotypes of NOS3.	Glycine	83-86	adrenoceptor beta 2	Homo sapiens	220-225
19373110-10	2009	Interestingly, the odds ratio was 7.64 for individuals having a combination of the Gly/Gly genotype of ADRB2 and Glu/Glu genotype of NOS3 when compared with those having a combination of Arg/Arg and Arg/Gly genotypes of ADRB2 and Asp/Asp and Asp/Glu genotypes of NOS3.	Glycine	87-90	adrenoceptor beta 2	Homo sapiens	103-108
19342448-6	2009	Function-blocking antibodies directed against integrin alpha5beta1 or soluble Arg-Gly-Asp peptide fragments derived from FN specifically inhibited GPR30-mediated epidermal growth factor receptor transactivation.	Glycine	82-85	G protein-coupled estrogen receptor 1	Homo sapiens	147-152
19225614-1	2009	A one-step S(N)Ar(H) reaction has been used for the synthesis of photostable probe , which has good water solubility and low cytotoxicity; this probe can be used for targeted imaging of tumour cells by virtue of specific binding between integrin alpha(v)beta(3) and an arginine-glycine-aspartic acid tripeptide sequence.	Glycine	278-285	integrin subunit alpha V	Homo sapiens	237-261
19236233-6	2009	K57 substitution with a glycine in sCD38p impaired its ability to inhibit syncytia formation in MT-2/H9(IIIB) cell cocultures and gp120 binding to CD4 in a mouse T cell line expressing human but not mouse CD4.	Glycine	24-31	CD4 antigen	Mus musculus	147-150
19236233-6	2009	K57 substitution with a glycine in sCD38p impaired its ability to inhibit syncytia formation in MT-2/H9(IIIB) cell cocultures and gp120 binding to CD4 in a mouse T cell line expressing human but not mouse CD4.	Glycine	24-31	CD4 antigen	Mus musculus	205-208
19055526-3	2009	Hence, 11 variants of YscP(515) were generated by multiple Pro or Gly substitutions.	Glycine	66-69	required for Yop secretion	Yersinia enterocolitica	22-26
19055526-5	2009	Taking the secondary motifs into account, Pro/Gly-variants were subjected to in silico modelling to simulate the extension of YscP upon needle growth.	Glycine	46-49	required for Yop secretion	Yersinia enterocolitica	126-130
19214433-3	2009	The open reading frame consists of 157 amino acids with an N-terminal RNA-recognition motif and a C-terminal glycine-rich domain, and thus the cDNA clone was designated as Nicotiana tabaccum glycine-rich RNA-binding protein-1 (NtGRP1).	Glycine	191-198	glycine-rich RNA-binding protein-like	Nicotiana tabacum	227-233
18977415-12	2009	In conclusion, pharmacological inactivation of the glycine-binding site of NMDA receptors may control cannabinoid-induced relapse-like drinking, which is associated with altered expression of CNR1 and NR1 gene expression as observed after WIN treatment.	Glycine	51-58	cannabinoid receptor 1	Rattus norvegicus	192-196
20224238-1	2009	In the colony of Sprague-Dawley (SD) strain, we found that there were rats expressing a mutant AQP5, which has a point mutation at nt 308 (G308A), leading to a replacement of (103)Gly with (103)Asp in the 3rd transmembrane domain.	Glycine	180-183	aquaporin 5	Rattus norvegicus	95-99
19250433-0	2009	A novel glycine mutation in the COL7A1 gene leading to dominant dystrophic epidermolysis bullosa with intra-familial phenotypical heterogeneity.	Glycine	8-15	collagen type VII alpha 1 chain	Homo sapiens	32-38
19250433-4	2009	Finally, mutational analysis revealed a novel glycine substitution mutation in the COL7A1 gene in three affected family members.	Glycine	46-53	collagen type VII alpha 1 chain	Homo sapiens	83-89
19059068-4	2008	A common single nucleotide polymorphism (SNP) in the beta2-adrenergic receptor gene (ADRB2) results in an arginine substitution for glycine at amino acid 16 (Arg16--&gt;Gly) of the beta2-adrenergic receptor protein.	Glycine	169-172	adrenoceptor beta 2	Homo sapiens	53-78
19059068-4	2008	A common single nucleotide polymorphism (SNP) in the beta2-adrenergic receptor gene (ADRB2) results in an arginine substitution for glycine at amino acid 16 (Arg16--&gt;Gly) of the beta2-adrenergic receptor protein.	Glycine	169-172	adrenoceptor beta 2	Homo sapiens	85-90
19059068-4	2008	A common single nucleotide polymorphism (SNP) in the beta2-adrenergic receptor gene (ADRB2) results in an arginine substitution for glycine at amino acid 16 (Arg16--&gt;Gly) of the beta2-adrenergic receptor protein.	Glycine	169-172	adrenoceptor beta 2	Homo sapiens	181-206
18824048-7	2008	AtPep1(9-23) was used for alanine-substitution analysis and revealed two important residues for activity, a serine, [A(15)]AtPep1(9-23) (12 max approximately 10nM), and a glycine, [A(17)]AtPep1(9-23) (12 max approximately 1000 nM).	Glycine	171-178	precursor of peptide 1	Arabidopsis thaliana	0-6
18824048-9	2008	The importance of the glycine residue for binding to the AtPep receptor was also confirmed by competition assays using radiolabeled AtPep1.	Glycine	22-29	precursor of peptide 1	Arabidopsis thaliana	132-138
18824048-11	2008	Homologs of AtPep1 identified in Arabidopsis and other species revealed a strict conservation of the glycine residue.	Glycine	101-108	precursor of peptide 1	Arabidopsis thaliana	12-18
18793697-2	2008	Since the concentration of glycine in the synaptic cleft is controlled by specialized proteins, the glycine transporters GlyT1 and GlyT2, manipulation of this system might have significant effects on nociception.	Glycine	27-34	solute carrier family 6 member 9	Rattus norvegicus	121-126
18377692-8	2008	These results suggest that dietary Gly supplementation modulates the inflammatory response partly through changes in the expression of pro-inflammatory cytokines such as IL-1, IL-6, IFN-gamma and TL1A.	Glycine	35-38	interleukin 6	Gallus gallus	176-180
18377692-8	2008	These results suggest that dietary Gly supplementation modulates the inflammatory response partly through changes in the expression of pro-inflammatory cytokines such as IL-1, IL-6, IFN-gamma and TL1A.	Glycine	35-38	interferon gamma	Gallus gallus	182-191
19301767-6	2008	Interactions that increased the risk for HF were found in patients carrying at least one of the beta2-AR Glu and beta2-AR Gly allele (OR = 3.81; 95% CI = 1.50-0.70) and beta2-AR Glu and beta1-AR Gly allele combination (OR = 5.51; 95% CI = 2.19-13.86).	Glycine	122-125	adrenoceptor beta 2	Homo sapiens	96-104
19301767-6	2008	Interactions that increased the risk for HF were found in patients carrying at least one of the beta2-AR Glu and beta2-AR Gly allele (OR = 3.81; 95% CI = 1.50-0.70) and beta2-AR Glu and beta1-AR Gly allele combination (OR = 5.51; 95% CI = 2.19-13.86).	Glycine	122-125	adrenoceptor beta 2	Homo sapiens	113-121
19301767-6	2008	Interactions that increased the risk for HF were found in patients carrying at least one of the beta2-AR Glu and beta2-AR Gly allele (OR = 3.81; 95% CI = 1.50-0.70) and beta2-AR Glu and beta1-AR Gly allele combination (OR = 5.51; 95% CI = 2.19-13.86).	Glycine	122-125	adrenoceptor beta 2	Homo sapiens	113-121
19301767-6	2008	Interactions that increased the risk for HF were found in patients carrying at least one of the beta2-AR Glu and beta2-AR Gly allele (OR = 3.81; 95% CI = 1.50-0.70) and beta2-AR Glu and beta1-AR Gly allele combination (OR = 5.51; 95% CI = 2.19-13.86).	Glycine	195-198	adrenoceptor beta 2	Homo sapiens	96-104
19301767-6	2008	Interactions that increased the risk for HF were found in patients carrying at least one of the beta2-AR Glu and beta2-AR Gly allele (OR = 3.81; 95% CI = 1.50-0.70) and beta2-AR Glu and beta1-AR Gly allele combination (OR = 5.51; 95% CI = 2.19-13.86).	Glycine	195-198	adrenoceptor beta 2	Homo sapiens	113-121
18755167-1	2008	The neuron-specific K-Cl cotransporter (KCC2) maintains a low intracellular Cl(-) concentration in neurons and is necessary for fast hyperpolarizing responses to GABA and glycine.	Glycine	171-178	solute carrier family 12 member 5	Homo sapiens	40-44
19061625-7	2008	Both disease subsets are characterized by the late age of onset, nail dystrophy, and predominantly pretibial pruritic lichenoid skin lesion; they are associated with glycine substitution mutations in COL7A1.	Glycine	166-173	collagen type VII alpha 1 chain	Homo sapiens	200-206
19082310-11	2008	The genetic analysis of tumoral DNA revealed point mutations in two different genes: the wild type CAA at codon 61 of N-RAS mutated to CAT, replacing glycine by histidine (G61H) and the normal GCC sequence at codon 623 of the TSHR gene was replaced by TCC, changing the alanine by serine (A623S).	Glycine	150-157	NRAS proto-oncogene, GTPase	Homo sapiens	118-123
18815261-1	2008	At inhibitory synapses, glycine and GABA are accumulated into synaptic vesicles by the same vesicular transporter VGAT/VIAAT (vesicular GABA transporter/vesicular inhibitory amino acid transporter), enabling a continuum of glycine, GABA, and mixed phenotypes.	Glycine	24-31	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	114-118
18815261-1	2008	At inhibitory synapses, glycine and GABA are accumulated into synaptic vesicles by the same vesicular transporter VGAT/VIAAT (vesicular GABA transporter/vesicular inhibitory amino acid transporter), enabling a continuum of glycine, GABA, and mixed phenotypes.	Glycine	24-31	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	119-124
18815261-1	2008	At inhibitory synapses, glycine and GABA are accumulated into synaptic vesicles by the same vesicular transporter VGAT/VIAAT (vesicular GABA transporter/vesicular inhibitory amino acid transporter), enabling a continuum of glycine, GABA, and mixed phenotypes.	Glycine	223-230	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	114-118
18815261-1	2008	At inhibitory synapses, glycine and GABA are accumulated into synaptic vesicles by the same vesicular transporter VGAT/VIAAT (vesicular GABA transporter/vesicular inhibitory amino acid transporter), enabling a continuum of glycine, GABA, and mixed phenotypes.	Glycine	223-230	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	119-124
17624491-4	2008	The mRNA expression of atrogin-1/MAFbx, proteasome C2 subunit, m-calpain large subunit, and cathepsin B was decreased by glycine in a dose-dependent manner.	Glycine	121-128	F-box protein 32	Gallus gallus	23-32
18507738-4	2008	p39 and p35 contain localization motifs, such as a second Gly for myristoylation and Lys clusters in the N-terminal p10 region.	Glycine	58-61	cyclin dependent kinase 5 regulatory subunit 1	Homo sapiens	8-11
18387950-6	2008	The results indicate that intracellular charges at the MFS TM2-3 and TM8-9 signature loops and flanking TMs 3, 5, and 6 are critical for the structure of GLUT1 as are TM glycines and that TM4, located at the catalytic core of MFS proteins, forms a helix that surfaces into the extracellular solution where another proton facilitates transport.	Glycine	170-178	solute carrier family 2 member 1	Homo sapiens	154-159
18268017-4	2008	By generating a series of chimeric and point mutants of p38alpha and p38beta, we found two amino acid residues (Asp(145) and Leu(156) in p38alpha, Gly(145) and Val(156) in p38beta) that determine the distinct subcellular locations of p38alpha-PRAK and p38beta-PRAK.	Glycine	147-150	MAP kinase-activated protein kinase 5	Mus musculus	243-247
18268017-4	2008	By generating a series of chimeric and point mutants of p38alpha and p38beta, we found two amino acid residues (Asp(145) and Leu(156) in p38alpha, Gly(145) and Val(156) in p38beta) that determine the distinct subcellular locations of p38alpha-PRAK and p38beta-PRAK.	Glycine	147-150	MAP kinase-activated protein kinase 5	Mus musculus	260-264
18250167-3	2008	Here, we report a novel K(ATP) channel gating defect caused by CHI-associated Kir6.2 mutations at arginine 301 (to cysteine, glycine, histidine, or proline).	Glycine	125-132	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	78-84
18096669-6	2008	SK-N-MC cells, which express neither PC1/3 nor PC2, synthesized alone the processing intermediate, glycine-extended CCK-22.	Glycine	99-106	cholecystokinin	Mus musculus	116-119
18946534-5	2008	Recent studies of the Na(+)/Cl(-)-dependent glycine transporters GlyT1 and GlyT2 using mouse knockout models and human genetics have revealed that mutations in GlyT2 are a second major cause of hyperekplexia, while the phenotype of the GlyT1 knockout mouse resembles a devastating neurological disorder known as glycine encephalopathy (OMIM 605899).	Glycine	44-51	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	160-165
18292428-11	2008	Sodium dodecyl sulfate and glycine enhanced GABA(A) receptor function, and the S270I mutation attenuated this effect.	Glycine	27-34	GABA(A) receptor-associated protein L homeolog	Xenopus laevis	44-51
18589597-11	2008	And the air pollutants, PM4, SO2 and CO, interacted with the Gly/Gly genotype at the 16th locus of beta2-AR gene or the DD genotype of ACE gene maybe increases the risk for asthma in children.	Glycine	61-64	adrenoceptor beta 2	Homo sapiens	99-107
18589597-11	2008	And the air pollutants, PM4, SO2 and CO, interacted with the Gly/Gly genotype at the 16th locus of beta2-AR gene or the DD genotype of ACE gene maybe increases the risk for asthma in children.	Glycine	65-68	adrenoceptor beta 2	Homo sapiens	99-107
18248890-0	2008	Tonic facilitation of glutamate release by glycine binding sites on presynaptic NR2B-containing NMDA autoreceptors in the rat visual cortex.	Glycine	43-50	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	80-84
18248890-7	2008	These results suggest that presynaptic NR2B-containing NMDA-Rs are located in layer II/III pyramidal neurons of the rat visual cortex, and that the glycine binding site of these type NMDA-Rs tonically regulates glutamate release.	Glycine	148-155	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	39-43
17904828-2	2008	For this purpose chitosan membranes were prepared and then photochemically modified with the cell adhesive peptide RGDS (Arg-Gly-Asp-Ser).	Glycine	125-128	ral guanine nucleotide dissociation stimulator	Mus musculus	115-119
18048007-0	2008	Glycine modulates synaptic NR2A- and NR2B-containing NMDA receptor-mediated responses in the rat visual cortex.	Glycine	0-7	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	37-41
18048007-5	2008	A specific antagonist for NR2B-NMDA-Rs, Ro 25-6981, reduced NMDA-R-mediated mEPSCs, and glycine with Ro 25-6981 enhanced NMDA-R-mediated mEPSCs.	Glycine	88-95	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	26-30
18048007-7	2008	Our data indicate that the glycine binding site of synaptic NR2A-containing and NR2B-containing NMDA-Rs does not saturate and that glycine may act as a modulator of NMDA-R-mediated transmission in layer II/III pyramidal neurons of the rat visual cortex.	Glycine	27-34	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	80-84
17884945-4	2008	In this study, fasted mice were administered Gly(2)-GLP-2 or LR(3)-IGF-I (positive control) for 0.5-4 h. Nuclear translocation of beta-catenin in non-Paneth crypt cells was assessed by immunohistochemistry and expression of its downstream proliferative markers, c-myc and Sox9, by quantitative RT-PCR.	Glycine	45-48	catenin (cadherin associated protein), beta 1	Mus musculus	130-142
17716783-7	2008	Nevertheless, GLY significantly reduced extracellular/tissue AMPH ratios in both PFC and striatum (STR), especially following PCP administration, suggesting a feedback mediated effect on the dopamine transporter.	Glycine	14-17	solute carrier family 6 member 3	Homo sapiens	191-211
17716783-9	2008	These findings suggest that GLY may modulate DA release in brain by producing feedback regulation of dopamine transporter function, possibly via potentiation of NMDA-stimulated GABA release and presynaptic GABAB receptor activation.	Glycine	28-31	solute carrier family 6 member 3	Homo sapiens	101-121
18941301-4	2008	In both glycine cleavage and synthesis, aminomethyl moiety bound to lipoic acid of H-protein represents the intermediate that is degraded to or can be formed from N(5),N(10)-methylene-H(4)folate and ammonia by the action of T-protein.	Glycine	8-15	myosin binding protein H	Homo sapiens	83-92
18184549-6	2008	Abeta(1-40) affinity elements from the extract of HBR, eluted from Affi-gel-Abeta(1-40) by glycine solution (pH=2.5), could be detected by HPLC-fluorescent detector system.	Glycine	91-98	amyloid beta precursor protein	Rattus norvegicus	0-5
18184549-6	2008	Abeta(1-40) affinity elements from the extract of HBR, eluted from Affi-gel-Abeta(1-40) by glycine solution (pH=2.5), could be detected by HPLC-fluorescent detector system.	Glycine	91-98	amyloid beta precursor protein	Rattus norvegicus	76-81
17936513-3	2007	Most Cat-301+ GCL interneurons are glycine+ and all are densely innervated by a meshwork of calbindin+/glutamic acid decarboxylase+ Purkinje cell collaterals and their synapses.	Glycine	35-42	germ cell-less 2, spermatogenesis associated	Homo sapiens	14-17
17987109-0	2007	Glycine inhibitory dysfunction turns touch into pain through PKCgamma interneurons.	Glycine	0-7	protein kinase C, gamma	Rattus norvegicus	61-69
17987109-9	2007	It also provides evidence that glycine inhibitory dysfunction gates tactile input to nociceptive specific neurons through PKCgamma-dependent activation of a local, excitatory, NMDA receptor-dependent, circuit.	Glycine	31-38	protein kinase C, gamma	Rattus norvegicus	122-130
17962467-10	2007	Although high levels of glycine labeling in the outer cortex correlated well with the expression of the glycine transporter GLYT1, the absence of GLYT1 in the core, despite an increase of glycine in this region, suggests an alternative glycine uptake system such as GLYT2 exists in the core.	Glycine	104-111	solute carrier family 6 member 9	Rattus norvegicus	124-129
17962467-10	2007	Although high levels of glycine labeling in the outer cortex correlated well with the expression of the glycine transporter GLYT1, the absence of GLYT1 in the core, despite an increase of glycine in this region, suggests an alternative glycine uptake system such as GLYT2 exists in the core.	Glycine	104-111	solute carrier family 6 member 9	Rattus norvegicus	124-129
17828277-3	2007	Here we use the complex formed between the CAP-Gly domain of p150(glued) and the C-terminal zinc knuckle of CLIP170 as a model system to explore the structure-function relationship of CAP-Gly-mediated protein interactions.	Glycine	188-191	CAP-Gly domain containing linker protein 1	Homo sapiens	108-115
17828277-4	2007	We demonstrate that the conserved GKNDG motif of CAP-Gly domains is responsible for targeting to the C-terminal EEY/F sequence motifs of CLIP170, EB proteins and microtubules.	Glycine	53-56	CAP-Gly domain containing linker protein 1	Homo sapiens	137-144
17828277-5	2007	The CAP-Gly-EEY/F interaction is essential for the recruitment of the dynactin complex by CLIP170 and for activation of CLIP170.	Glycine	8-11	CAP-Gly domain containing linker protein 1	Homo sapiens	90-97
17828277-5	2007	The CAP-Gly-EEY/F interaction is essential for the recruitment of the dynactin complex by CLIP170 and for activation of CLIP170.	Glycine	8-11	CAP-Gly domain containing linker protein 1	Homo sapiens	120-127
17560037-2	2007	We report here the identification and characterisation of a novel naturally occurring transition that changes codon 169 from GGC (Gly) to GAC (Asp) in the human Pi class GST, GSTP1.	Glycine	130-133	gamma-glutamylcyclotransferase	Homo sapiens	125-128
17917856-1	2007	Extensive hydrogen bonding of dyes to connective tissue fibers is made possible by the high content of the amino acids proline and glycine in elastin and collagens.	Glycine	131-138	elastin	Homo sapiens	142-149
17914241-4	2007	Glycine 310 remains conserved for glucokinase and potassium channel KCNJ11.	Glycine	0-7	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	68-74
17554035-5	2007	In contrast, peptides bearing Glu-Gly at the scissile bond (p20/VPg and 3C(pro)/3D(pol) junctions) were resistant to trans-cleavage by 3C(pro) and 3CD(propol).	Glycine	34-37	tubulin polymerization promoting protein family member 3	Homo sapiens	60-63
17506495-0	2007	BDNF-mediated modulation of GABA and glycine release in dorsal horn lamina II from postnatal rats.	Glycine	37-44	brain-derived neurotrophic factor	Rattus norvegicus	0-4
17506495-2	2007	The role of BDNF in modulating GABA and glycine-mediated inhibitory transmission has not been fully investigated.	Glycine	40-47	brain-derived neurotrophic factor	Rattus norvegicus	12-16
17506495-4	2007	We show that application of BDNF enhanced the spontaneous release of GABA and glycine, in presence of tetrodotoxin.	Glycine	78-85	brain-derived neurotrophic factor	Rattus norvegicus	28-32
17506495-7	2007	Evoked GABA and glycine IPSCs (eIPSCs) were depressed by BDNF and the coefficient of variation of eIPSC amplitude was significantly increased.	Glycine	16-23	brain-derived neurotrophic factor	Rattus norvegicus	57-61
17506495-8	2007	By recording glycine eIPSCs with the paired-pulse protocol, an increase of paired-pulse ratio during BDNF application was observed.	Glycine	13-20	brain-derived neurotrophic factor	Rattus norvegicus	101-105
17462677-0	2007	Glycine-induced long-term synaptic potentiation is mediated by the glycine transporter GLYT1.	Glycine	0-7	solute carrier family 6 member 9	Rattus norvegicus	87-92
17462677-9	2007	In contrast, LTP-GLY is partially or totally blocked with the antagonists of glycine transporter GLYT1, sarcosine or ALX-5407, respectively.	Glycine	17-20	solute carrier family 6 member 9	Rattus norvegicus	97-102
17462677-10	2007	These results indicate that LTP-GLY requires the activation of GLYT1, a glycine transporter co-localized and associated to NMDA receptors.	Glycine	32-35	solute carrier family 6 member 9	Rattus norvegicus	63-68
17462677-11	2007	In addition, the fact that NMDA receptor inhibition increases LTP-GLY magnitude, opens the possibility that these receptors could have a negative control on GLYT1 activity.	Glycine	66-69	solute carrier family 6 member 9	Rattus norvegicus	157-162
20641448-0	2004	[(99m)Tc(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) [(99m)Tc-(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) ((99m)Tc(N)(PNP3)-CCK-8) is a radiolabeled peptide developed for single-photon emission computed tomography (SPECT) imaging of tumors that express the gastrin/cholecystokinin-2 (CCK-2) receptor (1).	Glycine	19-22	cholecystokinin	Rattus norvegicus	64-67
20641448-0	2004	[(99m)Tc(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) [(99m)Tc-(N)(NS-Cys-Gly-CCK-8)(PNP3)](+) ((99m)Tc(N)(PNP3)-CCK-8) is a radiolabeled peptide developed for single-photon emission computed tomography (SPECT) imaging of tumors that express the gastrin/cholecystokinin-2 (CCK-2) receptor (1).	Glycine	19-22	gastrin	Rattus norvegicus	232-239
18690025-5	2007	Our results suggest that the effect of mutation of the central glycine (at position 175 in Kir3.4) on betagamma-induced whole-cell currents is related to the extent of the interaction between residues located at the position of the central glycine and two residues, one located in the signature sequence of the selectivity filter (T149 in Kir3.4) and the other in the pore helix (E147 in Kir3.4).	Glycine	63-70	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	91-97
18690025-5	2007	Our results suggest that the effect of mutation of the central glycine (at position 175 in Kir3.4) on betagamma-induced whole-cell currents is related to the extent of the interaction between residues located at the position of the central glycine and two residues, one located in the signature sequence of the selectivity filter (T149 in Kir3.4) and the other in the pore helix (E147 in Kir3.4).	Glycine	63-70	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	339-345
18690025-5	2007	Our results suggest that the effect of mutation of the central glycine (at position 175 in Kir3.4) on betagamma-induced whole-cell currents is related to the extent of the interaction between residues located at the position of the central glycine and two residues, one located in the signature sequence of the selectivity filter (T149 in Kir3.4) and the other in the pore helix (E147 in Kir3.4).	Glycine	63-70	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	339-345
18690025-5	2007	Our results suggest that the effect of mutation of the central glycine (at position 175 in Kir3.4) on betagamma-induced whole-cell currents is related to the extent of the interaction between residues located at the position of the central glycine and two residues, one located in the signature sequence of the selectivity filter (T149 in Kir3.4) and the other in the pore helix (E147 in Kir3.4).	Glycine	240-247	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	91-97
18690025-5	2007	Our results suggest that the effect of mutation of the central glycine (at position 175 in Kir3.4) on betagamma-induced whole-cell currents is related to the extent of the interaction between residues located at the position of the central glycine and two residues, one located in the signature sequence of the selectivity filter (T149 in Kir3.4) and the other in the pore helix (E147 in Kir3.4).	Glycine	240-247	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	339-345
18690025-5	2007	Our results suggest that the effect of mutation of the central glycine (at position 175 in Kir3.4) on betagamma-induced whole-cell currents is related to the extent of the interaction between residues located at the position of the central glycine and two residues, one located in the signature sequence of the selectivity filter (T149 in Kir3.4) and the other in the pore helix (E147 in Kir3.4).	Glycine	240-247	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	339-345
17166900-4	2007	Generally, shorter V4 loops are incompatible with a glycine occurring in the alpha2-helix in clade C, an intriguing association that could be exploited to inform Env immunogen design.	Glycine	52-59	endogenous retrovirus group K member 20	Homo sapiens	162-165
18634571-5	2007	Simultaneously, the expression of glial amino acid transporters for glycine and glutamate (GlyT1 and GLT1) is reduced on pd 7 and pd 14.	Glycine	68-75	solute carrier family 1 (glial high affinity glutamate transporter), member 2	Mus musculus	101-105
18634571-6	2007	Consistent with a reduced expression of GlyT1 and GLT1, high performance liquid chromatography reveals a net increase in the concentration of glutamate and glycine on pd 7 and pd 14 in tissue from the lumbar spinal cord of neuropathic mice.	Glycine	156-163	solute carrier family 1 (glial high affinity glutamate transporter), member 2	Mus musculus	50-54
17188389-5	2007	Glycine protection required the activation of a signal pathway involving Src, Pyk2 and p38 MAP kinases.	Glycine	0-7	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	73-76
17188389-7	2007	The prevention of cell swelling by hepatocyte incubation in a hypertonic medium as well as the degradation of extracellular ATP with apyrase or the block P2 purinergic receptors with suramin reverted glycine-induced cytoprotection and inhibited Src, Pyk2 and p38 MAPK activation.	Glycine	200-207	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	245-248
17256796-1	2007	In classical achondroplasia (Ach), a glycine residue is replaced by an arginine at codon 380 in exon 10 of the fibroblast growth factor receptor 3 gene (FGFR3).	Glycine	37-44	fibroblast growth factor receptor 3	Homo sapiens	111-146
17256796-1	2007	In classical achondroplasia (Ach), a glycine residue is replaced by an arginine at codon 380 in exon 10 of the fibroblast growth factor receptor 3 gene (FGFR3).	Glycine	37-44	fibroblast growth factor receptor 3	Homo sapiens	153-158
17158459-2	2007	It is abundant in the liver, where it uses excess S-adenosylmethionine (AdoMet) to methylate glycine to N-methylglycine (sarcosine) and produces S-adenosylhomocysteine (AdoHcy), thereby controlling the methylating potential of the cell.	Glycine	93-100	methionine adenosyltransferase 1A	Rattus norvegicus	72-78
17260973-7	2007	The binding site of GGT for the Cys-Gly moiety of glutathione or for the acceptor molecules was probed by the phosphonate diesters to reveal a significant difference in the mechanism of substrate recognition between E. coli and human GGT.	Glycine	36-39	inactive glutathione hydrolase 2	Homo sapiens	20-23
17260973-7	2007	The binding site of GGT for the Cys-Gly moiety of glutathione or for the acceptor molecules was probed by the phosphonate diesters to reveal a significant difference in the mechanism of substrate recognition between E. coli and human GGT.	Glycine	36-39	inactive glutathione hydrolase 2	Homo sapiens	234-237
17141888-5	2007	The results of our studies indicate that the modulation of gammaGT activity can be used to change cellular redox status, and can affect Cys- and Cys-Gly-dependent S-thiolation and caspase-3 activity.	Glycine	149-152	inactive glutathione hydrolase 2	Homo sapiens	59-66
17584073-11	2007	Experimental studies showed that the renal tissue AM-mature/AM-glycine ratio is higher than that in plasma and urine.	Glycine	63-70	adrenomedullin	Homo sapiens	50-52
17584073-11	2007	Experimental studies showed that the renal tissue AM-mature/AM-glycine ratio is higher than that in plasma and urine.	Glycine	63-70	adrenomedullin	Homo sapiens	60-62
17994383-0	2007	Alpha78(EF7)Asn--&gt;Asp is a posttranslational modification in Hb J-Singapore [alpha78(EF7)Asn--&gt;Asp;alpha79(EF8)Ala--&gt;Gly].	Glycine	126-129	FAM3 metabolism regulating signaling molecule D	Homo sapiens	8-11
17994383-0	2007	Alpha78(EF7)Asn--&gt;Asp is a posttranslational modification in Hb J-Singapore [alpha78(EF7)Asn--&gt;Asp;alpha79(EF8)Ala--&gt;Gly].	Glycine	126-129	FAM3 metabolism regulating signaling molecule D	Homo sapiens	88-91
16978906-9	2007	In summary, we propose that arginine-glycine-aspartic acid-serine activates Integrin linked kinase via the Phosphoinositol-3 kinase pathway and this leads to activation of c-jun and c-fos and increased Activator protein-1 binding and Transforming growth factor-beta1 promoter activity.	Glycine	37-44	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	172-177
16978906-9	2007	In summary, we propose that arginine-glycine-aspartic acid-serine activates Integrin linked kinase via the Phosphoinositol-3 kinase pathway and this leads to activation of c-jun and c-fos and increased Activator protein-1 binding and Transforming growth factor-beta1 promoter activity.	Glycine	37-44	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	182-187
16978906-9	2007	In summary, we propose that arginine-glycine-aspartic acid-serine activates Integrin linked kinase via the Phosphoinositol-3 kinase pathway and this leads to activation of c-jun and c-fos and increased Activator protein-1 binding and Transforming growth factor-beta1 promoter activity.	Glycine	37-44	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	202-221
17374341-3	2007	In 597 patients treated by a beta-blocker and followed for 3 years after a myocardial infarction or an acute coronary syndrome, the death rate was 5.4 times higher in homozygous Arg 16 and Gln 27 B2AR genotypes than in heterozygous or homozygous Gly 16 and Glu 27 B2AR genotypes.	Glycine	246-249	adrenoceptor beta 2	Homo sapiens	196-200
16901987-7	2006	The nucleotide sequence of AQP5 cDNA from low producers indicated the existence of a point mutation at nt 308 (G308A), leading to a replacement of (103)Gly with (103)Asp in the third transmembrane domain, but no alteration was detected in the Kozak area.	Glycine	152-155	aquaporin 5	Rattus norvegicus	27-31
17374253-4	2006	RESULTS: GGT to GTT mutation at codon 12 of the K-ras gene was found in one conventional serous borderline tumors, resulting in valine to glycine substitution.	Glycine	138-145	KRAS proto-oncogene, GTPase	Homo sapiens	48-53
17010310-2	2006	Apobec1 is regulated by ACF (Apobec1 complementation factor) and hnRNPQ, which contains an N-terminal "acidic domain" (AcD) of unknown function, three RNA recognition motifs, and an Arg/Gly-rich region.	Glycine	186-189	APOBEC1 complementation factor	Homo sapiens	29-59
17085964-6	2006	Mutagenesis experiments showed that the residues that are absolutely conserved across the TRP family, including His11, Arg51, His102, and the C-terminal Tyr-Arg-Gly-Ser, may constitute the active site of mTRP.	Glycine	161-164	lysosomal-associated protein transmembrane 4A	Mus musculus	90-93
17085964-6	2006	Mutagenesis experiments showed that the residues that are absolutely conserved across the TRP family, including His11, Arg51, His102, and the C-terminal Tyr-Arg-Gly-Ser, may constitute the active site of mTRP.	Glycine	161-164	lysosomal-associated protein transmembrane 4A	Mus musculus	204-208
16298104-7	2006	Mutational analysis of a non-canonical residue (glycine 24) in human PCP-2 GL1 provided evidence for heterogeneity in mechanisms of Galphai interactions with GoLoco motifs.	Glycine	48-55	Purkinje cell protein 2	Homo sapiens	69-74
16635486-15	2006	The molecular identification and localisation of GLYT1 and ASCT2 in the lens suggests that these transporters may be responsible for the uptake of the precursor amino acids, glycine and glutamine, which are involved in GSH synthesis.	Glycine	174-181	solute carrier family 6 member 9	Rattus norvegicus	49-54
16923137-4	2006	The case 1 and 2 patients and their fathers revealed a heterozygous nucleotide G to A transition at position 6109 and 6082 in 73 exon of COL7A1, which resulted in a glycine to arginine substitution (G2037R and G2028R), respectively.	Glycine	165-172	collagen type VII alpha 1 chain	Homo sapiens	137-143
16529937-1	2006	Herein, we report on the identification of three potent glycine and related amino acid-based series of FXa inhibitors containing a neutral P1 chlorophenyl pharmacophore.	Glycine	56-63	coagulation factor X	Homo sapiens	103-106
16529937-2	2006	A X-ray crystal structure has shown that constrained glycine derivatives with optimized N-substitution can greatly increase hydrophobic interactions in the FXa active site.	Glycine	53-60	coagulation factor X	Homo sapiens	156-159
16751100-6	2006	Additionally, interactions with the C-terminal, mildly hydrophobic Gly-Gly-Met repeat sequences of GroEL protruding into the cavity, and repulsion effects from the negatively charged cavity wall were required for rapid folding of some proteins.	Glycine	67-70	heat shock protein family D (Hsp60) member 1	Homo sapiens	99-104
16751100-6	2006	Additionally, interactions with the C-terminal, mildly hydrophobic Gly-Gly-Met repeat sequences of GroEL protruding into the cavity, and repulsion effects from the negatively charged cavity wall were required for rapid folding of some proteins.	Glycine	71-74	heat shock protein family D (Hsp60) member 1	Homo sapiens	99-104
16510258-1	2006	The goal of the present review is to summarize the main ultrastructural and immunocytochemical characteristics for glycine and GABA in commissural (COM) and tuberculo-ventral neurons (TV) of the DCN.	Glycine	115-122	decorin	Rattus norvegicus	195-198
16716838-0	2006	Inhibitory effect of Cd2+ on glycine-induced chloride current in rat hippocampal neurons.	Glycine	29-36	Cd2 molecule	Rattus norvegicus	21-24
16756473-5	2006	Sequence analyses revealed point mutations in two different genes: the normal ACC sequence at codon 620 of the TSHR gene was replaced by ATC, changing the threonine by isoleucine (T620I); and the wild-type GGT at codon 12 of Ki-RAS mutated to TGT, replacing glycine by cysteine (G12C).	Glycine	258-265	thyroid stimulating hormone receptor	Homo sapiens	111-115
16557226-11	2006	There was striking regenerative response 48 h after Gly-ARF characterized by enhanced BrdU incorporation and reduced expression of p27(Kip).	Glycine	52-55	calcium and integrin binding 1	Rattus norvegicus	135-138
16297463-0	2006	Mitogenic effects of both amidated and glycine-extended gastrin-releasing peptide in defunctioned and azoxymethane-treated rat colon in vivo.	Glycine	39-46	gastrin releasing peptide	Rattus norvegicus	56-81
16297463-7	2006	Treatment with amidated or glycine-extended gastrin-releasing peptide for 4 weeks using implanted mini-osmotic pumps resulted in a two- to three-fold increase in proliferation, and an increase in crypt height, in the defunctioned rectal mucosa (p&lt;0.001), with smaller but significant increases in the caecum and distal colon.	Glycine	27-34	gastrin releasing peptide	Rattus norvegicus	44-69
16503664-5	2006	The terminal cysteine found in these peptides replaces the N-terminal glycine present in native melittin and allows covalent binding to other molecules.	Glycine	70-77	melittin	Apis mellifera	96-104
16326711-3	2006	GTA and GTB differ in only four "critical" amino acid residues (Arg/Gly-176, Gly/Ser-235, Leu/Met-266, and Gly/Ala-268).	Glycine	68-71	integrin subunit alpha 2b	Homo sapiens	0-3
16326711-3	2006	GTA and GTB differ in only four "critical" amino acid residues (Arg/Gly-176, Gly/Ser-235, Leu/Met-266, and Gly/Ala-268).	Glycine	77-80	integrin subunit alpha 2b	Homo sapiens	0-3
16326711-3	2006	GTA and GTB differ in only four "critical" amino acid residues (Arg/Gly-176, Gly/Ser-235, Leu/Met-266, and Gly/Ala-268).	Glycine	77-80	integrin subunit alpha 2b	Homo sapiens	0-3
16638323-1	2006	OBJECTIVE: Osteogenesis imperfecta (OI) is a congenital disease of connective tissue of increased bone fragility and low bone mass, most often caused by single amino acid substitution of glycine residues in the collagen, type I, alpha 1 protein (COL1A1) gene or the collagen, type I, alpha 2 protein (COL1A2) gene, encoding type I procollagen chains.	Glycine	187-194	collagen type I alpha 1 chain	Homo sapiens	211-236
16638323-1	2006	OBJECTIVE: Osteogenesis imperfecta (OI) is a congenital disease of connective tissue of increased bone fragility and low bone mass, most often caused by single amino acid substitution of glycine residues in the collagen, type I, alpha 1 protein (COL1A1) gene or the collagen, type I, alpha 2 protein (COL1A2) gene, encoding type I procollagen chains.	Glycine	187-194	collagen type I alpha 1 chain	Homo sapiens	246-252
16638323-1	2006	OBJECTIVE: Osteogenesis imperfecta (OI) is a congenital disease of connective tissue of increased bone fragility and low bone mass, most often caused by single amino acid substitution of glycine residues in the collagen, type I, alpha 1 protein (COL1A1) gene or the collagen, type I, alpha 2 protein (COL1A2) gene, encoding type I procollagen chains.	Glycine	187-194	collagen type I alpha 1 chain	Homo sapiens	211-219
16638323-1	2006	OBJECTIVE: Osteogenesis imperfecta (OI) is a congenital disease of connective tissue of increased bone fragility and low bone mass, most often caused by single amino acid substitution of glycine residues in the collagen, type I, alpha 1 protein (COL1A1) gene or the collagen, type I, alpha 2 protein (COL1A2) gene, encoding type I procollagen chains.	Glycine	187-194	collagen type I alpha 1 chain	Homo sapiens	221-227
16638323-11	2006	Since only few of nucleotide changes in type I collagen glycine codons would result in an aspartic acid substitution, these are predicted to be infrequent.	Glycine	56-63	collagen type I alpha 1 chain	Homo sapiens	40-46
16638323-11	2006	Since only few of nucleotide changes in type I collagen glycine codons would result in an aspartic acid substitution, these are predicted to be infrequent.	Glycine	56-63	collagen type I alpha 1 chain	Homo sapiens	47-55
16557343-1	2006	COL7A1 glycine substitution (GS) mutations result in dominant and recessive dystrophic epidermolysis bullosa (DDEB and RDEB).	Glycine	7-14	collagen type VII alpha 1 chain	Homo sapiens	0-6
18175625-19	2006	A molecular study of the neoplastic tissue evidenced a typical mutation of the K-ras gene codon 12: the normal sequence GGT (glycine) was altered into GAT (aspartic acid).	Glycine	125-132	KRAS proto-oncogene, GTPase	Homo sapiens	79-84
16273544-2	2005	Two mutations at glycine 94, a single guanine insertion or deletion in PMP22, result in different reading frameshifts and, consequently, an extended G94fsX222 or a truncated G94fsX110 protein, respectively.	Glycine	17-24	peripheral myelin protein 22	Rattus norvegicus	71-76
16204236-7	2005	When a mutant form of pro-TRH, which has the dibasic sites of initial processing mutated to glycines, is expressed in AtT20 cells, a neuroendocrine cell line endogenously expressing PC1, both steady-state and pulse-chase experiments revealed that peptides derived from this mutant precursor are secreted in a constitutive fashion.	Glycine	92-100	thyrotropin releasing hormone	Mus musculus	22-29
16563272-5	2005	(3) Comparing the effect of beta-2-AR gene +46 variant on serum lipid in males with females, we found that females with Gly16/Gly genotype had the highest level of serum LDL-C.	Glycine	120-123	adrenoceptor beta 2	Homo sapiens	28-37
16563272-6	2005	CONCLUSIONS: These data show that Gly16/Gly genotype of beta-2-AR gene +46 A--&gt;G variant is associated with higher level of serum LDL-C in this population, especially in female.	Glycine	34-37	adrenoceptor beta 2	Homo sapiens	56-65
16225626-5	2005	Blistering occurred only during the first few months after birth, and all affected individuals were found to have a heterozygous glycine substitution mutation in exon 45 of the type VII collagen gene, COL7A1, designated G1522E.	Glycine	129-136	collagen type VII alpha 1 chain	Homo sapiens	201-207
15956994-3	2005	Blocking the glycine transporter-1 (GlyT1) should, by increasing extracellular glycine levels, potentiate glutamatergic neurotransmission.	Glycine	13-20	solute carrier family 6 member 9	Rattus norvegicus	36-41
16143353-1	2005	The neurotransmitter glycine is removed from the synaptic cleft by two Na(+)-and Cl(-)-dependent transporters: GLYT1 and GLYT2.	Glycine	21-28	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	121-126
16143353-3	2005	GLYT2 is the transporter present in glycinergic neurons and provides cytosolic glycine for vesicular release from glycinergic terminals.	Glycine	36-43	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	0-5
16055441-4	2005	By using the glycine auxotroph Chinese hamster ovary glyB cell line, which lacks a functional MFT and is deficient in folates transport into mitochondria, we showed by complementation that AtFOLT1 functions as a folate transporter in a hamster background.	Glycine	13-20	folate transporter 1	Arabidopsis thaliana	189-196
16055441-5	2005	Indeed, stable transfectants bearing the AtFOLT1 cDNA have enhanced levels of folates in mitochondria and can support growth in glycine-free medium.	Glycine	128-135	folate transporter 1	Arabidopsis thaliana	41-48
15976057-6	2005	The deduced amino acid sequence of chicken adiponectin contains 22 glycine-X-Y repeats (in which X and Y represent any amino acid) at the N-terminal end as found in the mammalian adiponectin.	Glycine	67-74	adiponectin, C1Q and collagen domain containing	Gallus gallus	43-54
16002086-6	2005	We show that the Cbp peptide impacts deuterium incorporation into its binding partner (the SH2 domain), and into the SH2-kinase linker and several sequences in the kinase domain, including the glycine-rich loop in the active site.	Glycine	193-200	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	Homo sapiens	17-20
16100771-4	2005	RESULTS: Sequence analysis identified the existence of many polymorphisms; in codon 24 of exon 1, GGC (Gly) into GAC (Asp); in codon 30 of exon 1, CGG (Arg) into CGC (Arg); in exon 3 codon 169, ACA to ACG (both encoding for threonine); in exon 5, AGA to AGG (both encoding for arginine, codon 260); and T/C polymorphism in intron 2.	Glycine	103-106	gamma-glutamylcyclotransferase	Homo sapiens	98-101
15970667-3	2005	Recently, we have shown that MRE11 is arginine methylated in a C-terminal glycine-arginine rich (GAR) domain by protein arginine methyltransferase 1 (PRMT1).	Glycine	74-81	protein arginine methyltransferase 1	Homo sapiens	112-148
15970667-3	2005	Recently, we have shown that MRE11 is arginine methylated in a C-terminal glycine-arginine rich (GAR) domain by protein arginine methyltransferase 1 (PRMT1).	Glycine	74-81	protein arginine methyltransferase 1	Homo sapiens	150-155
15946904-3	2005	RESULTS: Three common polymorphisms were abundant in at least one allele in beta2AR resulting in a cysteine to arginine in the 5" promoter region (72% of patients), an arginine to glycine at amino acid-16 (Gly16; 86%), and a glutamine to glutamic acid at amino acid-27 (Glu27; 66%), a frequency that was no different to the normal Caucasian population.	Glycine	180-187	adrenoceptor beta 2	Homo sapiens	76-83
15936459-4	2005	After screening the protein coding exons (exons 1-5), we identified two novel missense mutations, Cys (TGC) to Gly (GGC) at codon 7 (C7G) and Leu (TTG) to Met (ATG) at codon 124 (L124M), and a single nucleotide substitution (-31c/t) in the intron 2.	Glycine	111-114	gamma-glutamylcyclotransferase	Homo sapiens	116-119
15956340-6	2005	Other perturbations, such as those of Gly 19 and Asp 20 of IGF-I (and the corresponding residues in IGF-II) - which are located in a reverse turn linking N-domain and C-domain interactive surfaces - are due to local conformational changes in the IGF-I and -II.	Glycine	38-41	insulin like growth factor 2	Bos taurus	59-64
15617517-2	2005	In contrast with human TFPI, Ixolaris binds tightly to the zymogen FX (Factor X) and to dansyl-Glu-Gly-Arg-chloromethyl ketone-treated FXa (DEGR-FXa; active-site-blocked FXa), indicating that exosites are involved in the FX(a)-Ixolaris interaction.	Glycine	99-102	coagulation factor X	Homo sapiens	135-138
15617517-2	2005	In contrast with human TFPI, Ixolaris binds tightly to the zymogen FX (Factor X) and to dansyl-Glu-Gly-Arg-chloromethyl ketone-treated FXa (DEGR-FXa; active-site-blocked FXa), indicating that exosites are involved in the FX(a)-Ixolaris interaction.	Glycine	99-102	coagulation factor X	Homo sapiens	140-148
15898744-6	2005	The FP assay was successfully applied to measure the binding affinity to integrin alpha(v)beta(3) of several cyclic peptides containing the Arg-Gly-Asp (RGD) motif.	Glycine	144-147	integrin subunit alpha V	Homo sapiens	73-97
15971150-2	2005	Adrenomedullin is processed from the inactive intermediate adrenomedullin precursor with a glycine extension, which is subsequently converted to biologically active mature adrenomedullin by enzymatic amidation.	Glycine	91-98	adrenomedullin	Homo sapiens	0-14
15971150-2	2005	Adrenomedullin is processed from the inactive intermediate adrenomedullin precursor with a glycine extension, which is subsequently converted to biologically active mature adrenomedullin by enzymatic amidation.	Glycine	91-98	adrenomedullin	Homo sapiens	59-73
15728199-6	2005	The mutation consisted of the substitution of a glycine residue with a serine at position 63 (G63S) in the DNA-binding GCM domain of GCMB.	Glycine	48-55	glial cells missing transcription factor 2	Homo sapiens	133-137
15769453-5	2005	RESULTS: (1) IL-1beta time-dependently increased the levels of two molecular forms of adrenomedullin, adrenomedullin-mature and adrenomedullin-glycine (P&lt;0.01).	Glycine	142-150	adrenomedullin	Rattus norvegicus	86-100
15608072-9	2005	Entrapping the recombinant activated tyrosine kinase pp60(c-Src) strongly potentiated the release of norepinephrine elicited by NMDA/glycine in Mg2+-free medium but failed to permit NMDA receptor activation in presence of external Mg2+ ions.	Glycine	133-140	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	58-63
15837193-6	2005	The crystal structure shows that although the catalytic site closely resembles that of other protein kinases, the activation segment contains Wee1-specific features that maintain it in an active conformation and, together with a key substitution in its glycine-rich loop, help determine its substrate specificity.	Glycine	253-260	WEE1 G2 checkpoint kinase	Homo sapiens	142-146
15854340-4	2005	High performance liquid chromatography was employed to monitor the continuous changes of glutamic acid (Glu), aspartic acid (Asp), Tau and glycine (Gly) in the hippocampus CA1 region at anaesthesia periods, CPB stage, pre 30 minutes in DHCA, post 30 minutes in DHCA, pre 30 minutes in rewarming, post 30 minutes in rewarming.	Glycine	148-151	carbonic anhydrase 1	Oryctolagus cuniculus	172-175
15772895-12	2005	An alternate approach to partial glycine agonists is to inhibit the uptake carrier(s) for glycine (ie, GlyT-1 and GlyT-2), thereby potentiating the lifetime of synaptic glycine.	Glycine	90-97	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	114-120
15772895-12	2005	An alternate approach to partial glycine agonists is to inhibit the uptake carrier(s) for glycine (ie, GlyT-1 and GlyT-2), thereby potentiating the lifetime of synaptic glycine.	Glycine	90-97	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	114-120
15598699-2	2005	In the sheep, placental conversion of maternal serine by serine hydroxymethyltransferase (SHMT) provides almost all the glycine transported to the fetus.	Glycine	120-127	serine hydroxymethyltransferase, cytosolic	Ovis aries	57-88
15598699-2	2005	In the sheep, placental conversion of maternal serine by serine hydroxymethyltransferase (SHMT) provides almost all the glycine transported to the fetus.	Glycine	120-127	serine hydroxymethyltransferase, cytosolic	Ovis aries	90-94
15833937-4	2005	Men with Gly/Gly genotypes for both the beta1 and beta2 receptors showed significant increases (approximately 0.6%/yr) in BMI from childhood to adulthood.	Glycine	9-12	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	40-45
15833937-4	2005	Men with Gly/Gly genotypes for both the beta1 and beta2 receptors showed significant increases (approximately 0.6%/yr) in BMI from childhood to adulthood.	Glycine	13-16	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	40-45
15833937-6	2005	Women with Gly/Gly genotypes at the beta1-receptor and carrying at least one beta3-Arg allele showed notable increases in BMI.	Glycine	11-14	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	36-41
15833937-6	2005	Women with Gly/Gly genotypes at the beta1-receptor and carrying at least one beta3-Arg allele showed notable increases in BMI.	Glycine	15-18	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	36-41
15389799-0	2005	Effect of GGC (glycine) repeat length polymorphism in the human androgen receptor on androgen action.	Glycine	15-22	gamma-glutamylcyclotransferase	Homo sapiens	10-13
15389799-1	2005	BACKGROUND: The human androgen receptor (AR) contains glutamine (CAG) and glycine (GGC) repeat length polymorphisms.	Glycine	74-81	gamma-glutamylcyclotransferase	Homo sapiens	83-86
15537636-5	2005	Receptor conformation was probed with a fluorescent full agonist ligand, Alexa 488-conjugated Gly-[Nle(28,31)]CCK-(26-33), shown previously to decrease in anisotropy and lifetime when occupying a receptor in the active conformation (Harikumar, K. G., Pinon, D. L., Wessels, W. S., Prendergast, F. G., and Miller, L. J.	Glycine	94-97	cholecystokinin	Cricetulus griseus	110-113
15593303-6	2005	Our data show that mutation of either of the first two glycines (G97, G98) to alanine results in soluble, recombinant TCR that do not bind to recombinant antigen at detectable levels.	Glycine	55-63	adhesion G protein-coupled receptor G3	Mus musculus	65-68
15922102-7	2005	We hypothesize, therefore, that subjects that are homozygous for Gly at amino acid 16 of the beta2AR have higher baseline blood pressure than Arg16 homozygotes due to beta2AR-mediated increases in ENaC activity in the kidney, caused, at least in part, by greater beta2AR density or enhanced beta2AR function of the Gly16 group.	Glycine	65-68	adrenoceptor beta 2	Homo sapiens	167-174
15922102-7	2005	We hypothesize, therefore, that subjects that are homozygous for Gly at amino acid 16 of the beta2AR have higher baseline blood pressure than Arg16 homozygotes due to beta2AR-mediated increases in ENaC activity in the kidney, caused, at least in part, by greater beta2AR density or enhanced beta2AR function of the Gly16 group.	Glycine	65-68	adrenoceptor beta 2	Homo sapiens	167-174
15922102-7	2005	We hypothesize, therefore, that subjects that are homozygous for Gly at amino acid 16 of the beta2AR have higher baseline blood pressure than Arg16 homozygotes due to beta2AR-mediated increases in ENaC activity in the kidney, caused, at least in part, by greater beta2AR density or enhanced beta2AR function of the Gly16 group.	Glycine	65-68	adrenoceptor beta 2	Homo sapiens	167-174
15601840-3	2005	We show here that both S. pombe and human Smc5 and -6 interact through their hinge domains and that four independent temperature-sensitive mutants of Rad18 (Smc6) are all mutated at the same glycine residue in the hinge region.	Glycine	191-198	RAD18 E3 ubiquitin protein ligase	Homo sapiens	150-155
15601840-4	2005	This mutation abolishes the interactions between the hinge regions of Rad18 (Smc6) and Spr18 (Smc5), as does mutation of a conserved glycine in the hinge region of Spr18 (Smc5).	Glycine	133-140	RAD18 E3 ubiquitin protein ligase	Homo sapiens	70-75
15354184-7	2005	Moreover, in dissociated pyramidal neurons of the CA1 region, NAAG also reduced the NMDA current and this effect was reversed by glycine.	Glycine	129-136	carbonic anhydrase 1	Homo sapiens	50-53
15610161-4	2004	Immunocytochemistry and confocal microscopy were used for codetection of VIAAT, the common presynaptic vesicular transporter of glycine and GABA, GlyRs, GABA(A)R alpha1 and gamma2 subunits, and gephyrin, the scaffold protein implicated in the synaptic localization of inhibitory receptors.	Glycine	128-135	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	73-78
15575003-7	2004	RESULTS: The mutation p.C347G (c.1039T &gt; G) results in a conserved cysteine to glycine amino acid substitution in the uromodulin zona pellucida (ZP) domain.	Glycine	82-100	uromodulin	Homo sapiens	121-131
15355958-9	2004	An in vitro assay showed that Gly(120) is essential for carboxyl-terminal cleavage by human Atg4B as well as for formation of the intermediates Atg7-MAP1LC3B (ubiquitin-activating enzyme-substrate) and Atg3-MAP1LC3B (ubiquitin carrier protein-substrate).	Glycine	30-33	autophagy related 3	Homo sapiens	202-206
15302873-1	2004	Glutathione synthetase (GS) catalyzes the ATP-dependent formation of the ubiquitous peptide glutathione from gamma-glutamylcysteine and glycine.	Glycine	136-143	glutathione synthetase 2	Arabidopsis thaliana	0-22
15604781-2	2004	The B. mori LIM protein homologue is classified into group 2 LIM proteins that contain glycine-rich LIM domain.	Glycine	87-94	muscle LIM protein	Bombyx mori	12-23
15350130-5	2004	Glycine is never observed in native TIM hinge sequences.	Glycine	0-7	triosephosphate isomerase 1	Gallus gallus	36-39
15341735-0	2004	The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma.	Glycine	8-11	CYLD lysine 63 deubiquitinase	Homo sapiens	22-26
15341735-3	2004	The two proteins bind to a region of CYLD that contains a Cys-box motif and the third cytoskeleton-associated protein-glycine conserved (CAP-Gly) domain.	Glycine	118-125	CYLD lysine 63 deubiquitinase	Homo sapiens	37-41
15341735-3	2004	The two proteins bind to a region of CYLD that contains a Cys-box motif and the third cytoskeleton-associated protein-glycine conserved (CAP-Gly) domain.	Glycine	141-144	CYLD lysine 63 deubiquitinase	Homo sapiens	37-41
15265498-2	2004	A variety of alpha-amino acid derivatives were prepared as glycine transport inhibitors and their ability to block the uptake of [(14)C]-glycine in COS7 cells transfected with human glycine transporter-2 (hGlyT-2) was evaluated.	Glycine	137-144	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	205-212
15265498-5	2004	Introducing an achiral amino acid such as glycine, or incorporating geminal substitution in the alpha-position, led to a significant reduction in GlyT-2 inhibitory properties.	Glycine	42-49	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	146-152
15265499-2	2004	Several beta- and gamma-amino acid derivatives were prepared as glycine transport inhibitors and their ability to block the uptake of [(14)C]-glycine in COS7 cells transfected with human glycine transporter-2 (hGlyT-2) were evaluated.	Glycine	142-149	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	210-217
15309699-1	2004	BACKGROUND: In the final step of production of adrenomedullin (AM), an inactive intermediate form of glycine-extended AM (AM-glycine) is converted to the active mature form of adrenomedullin (AM-mature) by enzymatic amidation.	Glycine	101-108	adrenomedullin	Homo sapiens	47-61
15309699-1	2004	BACKGROUND: In the final step of production of adrenomedullin (AM), an inactive intermediate form of glycine-extended AM (AM-glycine) is converted to the active mature form of adrenomedullin (AM-mature) by enzymatic amidation.	Glycine	101-108	adrenomedullin	Homo sapiens	63-65
15309699-1	2004	BACKGROUND: In the final step of production of adrenomedullin (AM), an inactive intermediate form of glycine-extended AM (AM-glycine) is converted to the active mature form of adrenomedullin (AM-mature) by enzymatic amidation.	Glycine	101-108	adrenomedullin	Homo sapiens	118-120
15309699-1	2004	BACKGROUND: In the final step of production of adrenomedullin (AM), an inactive intermediate form of glycine-extended AM (AM-glycine) is converted to the active mature form of adrenomedullin (AM-mature) by enzymatic amidation.	Glycine	101-108	adrenomedullin	Homo sapiens	122-132
15309699-1	2004	BACKGROUND: In the final step of production of adrenomedullin (AM), an inactive intermediate form of glycine-extended AM (AM-glycine) is converted to the active mature form of adrenomedullin (AM-mature) by enzymatic amidation.	Glycine	101-108	adrenomedullin	Homo sapiens	176-190
15309699-1	2004	BACKGROUND: In the final step of production of adrenomedullin (AM), an inactive intermediate form of glycine-extended AM (AM-glycine) is converted to the active mature form of adrenomedullin (AM-mature) by enzymatic amidation.	Glycine	101-108	adrenomedullin	Homo sapiens	118-120
15211660-2	2004	Since the 3-bp deletion is predicted to result in loss of the 60th glycine in the N-SH2 domain that is directly involved in the intramolecular interaction between the N-SH2 and the PTP domains of the PTPN11 protein, this mutation would disrupt the N-SH2/PTP binding in the absence of a phosphopeptide, leading to an excessive phosphatase activity.	Glycine	67-74	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	200-206
15144888-4	2004	These KAPs also showed high glycine and serine contents (average 24.30 and 21.13 mol%, respectively), distinguishing from other UHS/HS KAP families located on human chromosomes 17 and 21.	Glycine	28-35	cyclin dependent kinase inhibitor 3	Homo sapiens	6-9
15064326-0	2004	Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels.	Glycine	146-153	solute carrier family 6 member 9	Rattus norvegicus	0-26
15064326-3	2004	Previous pharmacological studies suggest that the glycine transporter type 1 (GlyT1) maintains subsaturating concentrations of glycine at synaptic NMDARs.	Glycine	50-57	solute carrier family 6 member 9	Rattus norvegicus	78-83
15064326-4	2004	Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, can augment NMDAR currents and NMDAR-mediated functions such as LTP.	Glycine	40-47	solute carrier family 6 member 9	Rattus norvegicus	15-20
15064326-4	2004	Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, can augment NMDAR currents and NMDAR-mediated functions such as LTP.	Glycine	87-94	solute carrier family 6 member 9	Rattus norvegicus	15-20
15165238-3	2004	Here, we show that mutations in two essential VirA residues, His-474 and Gly-657, can be complemented by the formation of mixed heterodimers, indicating that each subunit of a VirA dimer transphosphorylates the opposite subunit.	Glycine	73-76	two-component VirA-like sensor kinase	Agrobacterium tumefaciens	46-50
15165238-3	2004	Here, we show that mutations in two essential VirA residues, His-474 and Gly-657, can be complemented by the formation of mixed heterodimers, indicating that each subunit of a VirA dimer transphosphorylates the opposite subunit.	Glycine	73-76	two-component VirA-like sensor kinase	Agrobacterium tumefaciens	176-180
15192815-9	2004	A mutation of CGC--&gt;GGC was found at codon 617 in one ABCD1 allele of the third patient"s mother, leading to the glycine for arginine substitution.	Glycine	116-123	gamma-glutamylcyclotransferase	Homo sapiens	23-26
15094065-1	2004	The three genes hTAF(II)68, EWS, and TLS (called the TET family) encode related RNA binding proteins containing an RNA recognition motif and three glycine-, arginine-, and proline-rich regions in the C-terminus and a degenerated repeat containing the consensus sequence Ser-Tyr-Gly-Gln-Ser in the N-terminus.	Glycine	147-154	TATA-box binding protein associated factor 15	Homo sapiens	16-26
15094065-1	2004	The three genes hTAF(II)68, EWS, and TLS (called the TET family) encode related RNA binding proteins containing an RNA recognition motif and three glycine-, arginine-, and proline-rich regions in the C-terminus and a degenerated repeat containing the consensus sequence Ser-Tyr-Gly-Gln-Ser in the N-terminus.	Glycine	278-281	TATA-box binding protein associated factor 15	Homo sapiens	16-26
15006370-3	2004	The active ICAM-1 peptides have a common Pro-Arg-Gly sequence that may be important for binding to LFA-1.	Glycine	49-52	intercellular adhesion molecule 1	Homo sapiens	11-17
15086562-0	2004	Homo-oligomerization of human corneodesmosin is mediated by its N-terminal glycine loop domain.	Glycine	75-82	corneodesmosin	Homo sapiens	30-44
15086562-3	2004	CDSN presents two serine- and glycine-rich domains in its N- and C-terminus that may fold into highly flexible and adhesive secondary structures called glycine loops.	Glycine	30-37	corneodesmosin	Homo sapiens	0-4
15086562-3	2004	CDSN presents two serine- and glycine-rich domains in its N- and C-terminus that may fold into highly flexible and adhesive secondary structures called glycine loops.	Glycine	152-159	corneodesmosin	Homo sapiens	0-4
15086562-6	2004	Experiments evidenced the homophilic adhesive properties of the N-terminal glycine loop domain, confirming its involvement in CDSN-CDSN interactions.	Glycine	75-82	corneodesmosin	Homo sapiens	126-130
15086562-6	2004	Experiments evidenced the homophilic adhesive properties of the N-terminal glycine loop domain, confirming its involvement in CDSN-CDSN interactions.	Glycine	75-82	corneodesmosin	Homo sapiens	131-135
15086562-9	2004	Moreover, molecular filtration analyses demonstrated for the first time that non-glycosylated CDSN is able to spontaneously form large homo-oligomers in vitro and that the N-terminal glycine loop domain is necessary for the formation of these macromolecular complexes.	Glycine	183-190	corneodesmosin	Homo sapiens	94-98
14699076-4	2004	We have identified two lysosomal targeting motifs that mediate the sorting of CLN3 in transfected nonneuronal and neuronal cells: an unconventional motif in the long C-terminal cytosolic tail consisting of a methionine and a glycine separated by nine amino acids [M(X)9G], and a more conventional dileucine motif, located in the large cytosolic loop domain and preceded by an acidic patch.	Glycine	225-232	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	78-82
14668964-14	2004	Patients expressing the homozygous gly-16 genotype of the beta(2)-adrenoceptor genotype receiving a LABA may benefit from the substitution of their usual SABA for an alternative reliever.	Glycine	35-38	adrenoceptor beta 2	Homo sapiens	58-78
15493717-7	2004	CONCLUSION: At codon 16 of the beta2-AR gene, maternal Arg-16 homozygosity protects against, and Gly-16 predisposes to spontaneous preterm birth.	Glycine	97-100	adrenoceptor beta 2	Homo sapiens	31-39
14975510-0	2004	A new proposal for the mechanism of glycine hydroxylation as catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM).	Glycine	36-43	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	74-123
14975510-0	2004	A new proposal for the mechanism of glycine hydroxylation as catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM).	Glycine	36-43	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	125-128
14975510-1	2004	The title enzyme, peptidylglycine alpha-hydroxylating monooxygenase (PHM), is essential to the in vivo generation of a wide variety of physiologically significant alpha-amidated peptide hormones from the corresponding C-terminal glycine-extended prohormones.	Glycine	26-33	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	69-72
14606895-1	2003	The concentration dependence of the pressure- and temperature-induced cloud point transition (Pc and Tc, respectively) of aqueous solutions of an elastin-like polypeptide with a repeating pentapeptide Val-Pro-Gly-Ile-Gly sequence (MGLDGSMG(VPGIG)40VPLE) was investigated by using apparent light scattering, differential scanning calorimetry, and circular dichroism methods.	Glycine	209-212	elastin	Homo sapiens	146-153
14581554-6	2003	For fibrillarin, the first 80 amino acids, which contain the glycine-arginine-rich region (the GAR domain), was determined to be the domain interactive with N. The N protein was able to bind to the full-length genomic RNA of PRRSV, and the RNA binding domain was identified as the region overlapping with the nuclear localization signal situated at positions 41 to 47.	Glycine	61-68	fibrillarin	Homo sapiens	4-15
27265574-0	2003	First Observation of Hemoglobin Pyrgos [ss83(EF7) Gly Asp] in Turkish Population.	Glycine	50-53	FAM3 metabolism regulating signaling molecule D	Homo sapiens	45-48
12883358-8	2003	In fact, spontaneous CD44s shedding was dependent on the presence of partial or complete O-glycosylation of four serine-glycine motifs localized in the membrane-proximal CD44 ectodomain.	Glycine	120-127	CD44 molecule (Indian blood group)	Homo sapiens	21-25
12883358-8	2003	In fact, spontaneous CD44s shedding was dependent on the presence of partial or complete O-glycosylation of four serine-glycine motifs localized in the membrane-proximal CD44 ectodomain.	Glycine	120-127	CD44 molecule (Indian blood group)	Homo sapiens	170-174
12906830-2	2003	Structures of glycosylasparaginase precursors in complex with a glycine inhibitor have revealed the backbone in the immediate vicinity of the scissile peptide bond to be in a distorted trans conformation, which is believed to be the driving force for the N-O acyl shift to break the peptide bond.	Glycine	64-71	aspartylglucosaminidase	Homo sapiens	14-34
12754200-3	2003	Here we used Affymetrix micro-array and Northern analysis to demonstrate that two enzymes involved in conjugation of bile acids to taurine and glycine, namely bile acid-CoA synthetase (BACS) and bile acid-CoA: amino acid N-acetyltransferase (BAT) are induced by FXR in rat liver.	Glycine	143-150	solute carrier family 27 member 5	Rattus norvegicus	159-183
12754200-3	2003	Here we used Affymetrix micro-array and Northern analysis to demonstrate that two enzymes involved in conjugation of bile acids to taurine and glycine, namely bile acid-CoA synthetase (BACS) and bile acid-CoA: amino acid N-acetyltransferase (BAT) are induced by FXR in rat liver.	Glycine	143-150	solute carrier family 27 member 5	Rattus norvegicus	185-189
12754200-3	2003	Here we used Affymetrix micro-array and Northern analysis to demonstrate that two enzymes involved in conjugation of bile acids to taurine and glycine, namely bile acid-CoA synthetase (BACS) and bile acid-CoA: amino acid N-acetyltransferase (BAT) are induced by FXR in rat liver.	Glycine	143-150	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	195-240
12754200-3	2003	Here we used Affymetrix micro-array and Northern analysis to demonstrate that two enzymes involved in conjugation of bile acids to taurine and glycine, namely bile acid-CoA synthetase (BACS) and bile acid-CoA: amino acid N-acetyltransferase (BAT) are induced by FXR in rat liver.	Glycine	143-150	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	242-245
12761825-5	2003	LYAAT-1-IR (immunoreactivity) levels varied among different neuroanatomical structures but were present in neurons independently of the neurotransmitter used (glutamate, GABA, acetylcholine, noradrenaline, serotonin, or glycine).	Glycine	220-227	solute carrier family 36 member 1	Rattus norvegicus	0-7
12775683-4	2003	Comparison of CTX-M-14 and CTX-M-27 showed that residue Gly-240 decreased Km for ceftazidime (205 versus 940 microM), but decreased hydrolytic activity against good substrates, such as cefotaxime (kcat, 113 versus 415 s-1), probably owing to the alteration of beta3 strand positioning during the catalytic process.	Glycine	56-59	CTX-M-14	Escherichia coli	14-22
12646567-3	2003	The nmdmc(-/-) cells are auxotrophic for glycine, demonstrating that NMDMC is the only methylenetetrahydrofolate dehydrogenase normally expressed in the mitochondria of these cell lines.	Glycine	41-48	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	4-9
12646567-3	2003	The nmdmc(-/-) cells are auxotrophic for glycine, demonstrating that NMDMC is the only methylenetetrahydrofolate dehydrogenase normally expressed in the mitochondria of these cell lines.	Glycine	41-48	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Homo sapiens	69-74
12686470-10	2003	Glycine-extended forms of gastrin-16 and gastrin-17 comprises 45% of the total gastrin immunoreactivity.	Glycine	0-7	gastrin	Rattus norvegicus	26-33
12551924-4	2003	Based on the sequence differences between CRP and cyclic nucleotide gated channel, three mutants of CRP were constructed: deletion (residues 54-56 in loop 3 were deleted), insertion (loop 4 was lengthened by 5 residues between Glu-78 and Gly-79) and double mutants.	Glycine	238-241	catabolite gene activator protein	Escherichia coli	100-103
12702148-2	2003	These mutations include G12D, which replaces a conserved glycine residue in the amino-terminus of Cx31 and is associated with a severe EKV phenotype.	Glycine	57-64	gap junction protein beta 3	Homo sapiens	98-102
12671900-3	2003	Mutational analysis in our patient showed a heterozygous missense mutation of the MDR3 gene that has not been described previously, which occurs in exon 14 at codon 535, and results in the substitution of glycine for aspartic acid.	Glycine	205-212	ATP binding cassette subfamily B member 4	Homo sapiens	82-86
12562917-8	2003	The actions of vitronectin were sensitive to RGD (Arg-Gly-Asp)-sequence-containing peptide, indicating the involvement of integrins as vitronectin receptors.	Glycine	54-57	vitronectin	Mus musculus	15-26
12590568-1	2003	Peptidylglycine alpha-hydroxylating monooxygenase (PHM) and dopamine beta-monooxygenase (DbetaM) are homologous copper-containing enzymes that catalyze an oxygen-dependent hydroxylation of peptide-extended glycine residues and phenethylamines, respectively.	Glycine	8-15	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	51-54
12475969-4	2003	We changed Gly at the P1"-position of the secondary site to Ala to produce eIF4G-1(DM).	Glycine	11-14	eukaryotic translation initiation factor 4 gamma 1	Homo sapiens	75-82
12540777-5	2003	However, stimulating NPR-C receptor with des-(Gln(18), Ser(19),Gly(20),Leu(21),Gly(22))-ANP fragment 4-23 amide (C-ANP) also increased hepatocyte tolerance to hypoxia.	Glycine	63-66	natriuretic peptide A	Rattus norvegicus	88-91
12540777-5	2003	However, stimulating NPR-C receptor with des-(Gln(18), Ser(19),Gly(20),Leu(21),Gly(22))-ANP fragment 4-23 amide (C-ANP) also increased hepatocyte tolerance to hypoxia.	Glycine	79-82	natriuretic peptide A	Rattus norvegicus	88-91
12573541-1	2003	The vesicular GABA transporter (VGAT) loads GABA from neuronal cytoplasm into synaptic vesicles and is selectively expressed in inhibitory neurons that contain GABA and/or glycine.	Glycine	172-179	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	4-30
12573541-1	2003	The vesicular GABA transporter (VGAT) loads GABA from neuronal cytoplasm into synaptic vesicles and is selectively expressed in inhibitory neurons that contain GABA and/or glycine.	Glycine	172-179	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	32-36
12482550-5	2003	The methionine synthase gene (MTR) mutation is an A to G substitution, 2756A--&gt;G, which converts an aspartate to a glycine codon.	Glycine	118-125	5-methyltetrahydrofolate-homocysteine methyltransferase	Homo sapiens	4-23
12866360-6	2003	GPLGV pentapeptide was used as a substrate for MMP-2 and MMP-9, where the cleavage of Gly-Val bond by MMP was expected.	Glycine	86-89	matrix metallopeptidase 2	Mus musculus	47-52
12866360-6	2003	GPLGV pentapeptide was used as a substrate for MMP-2 and MMP-9, where the cleavage of Gly-Val bond by MMP was expected.	Glycine	86-89	matrix metallopeptidase 2	Mus musculus	47-50
12732238-4	2003	The soluble RGD-containing peptide glycine-arginine-glycine-aspartate-serine-proline (GRGDSP) increased neurotrophin mRNA levels in transcript- and subfield-specific fashions.	Glycine	35-42	brain derived neurotrophic factor	Homo sapiens	104-116
12732238-4	2003	The soluble RGD-containing peptide glycine-arginine-glycine-aspartate-serine-proline (GRGDSP) increased neurotrophin mRNA levels in transcript- and subfield-specific fashions.	Glycine	52-59	brain derived neurotrophic factor	Homo sapiens	104-116
14526489-8	2003	The homozygous glycine-16 (Arg--&gt;Gly) variant of the beta 2-adrenoceptor is known to predispose to agonist-induced down-regulation and desensitization, and may play a role in the pathogenesis of asthma severity.	Glycine	15-22	adrenoceptor beta 2	Homo sapiens	56-75
14526489-8	2003	The homozygous glycine-16 (Arg--&gt;Gly) variant of the beta 2-adrenoceptor is known to predispose to agonist-induced down-regulation and desensitization, and may play a role in the pathogenesis of asthma severity.	Glycine	36-39	adrenoceptor beta 2	Homo sapiens	56-75
12270926-7	2002	TRH-[Gly(4)-Lys(5)-Arg(6)] and TRH-[Gly(4)-Lys(5)] represent approximately 45% of the total TRH-like immunoreactivity in Cpe(fat/fat) mice; they constitute approximately 1% in controls.	Glycine	36-39	thyrotropin releasing hormone	Mus musculus	31-34
12270926-7	2002	TRH-[Gly(4)-Lys(5)-Arg(6)] and TRH-[Gly(4)-Lys(5)] represent approximately 45% of the total TRH-like immunoreactivity in Cpe(fat/fat) mice; they constitute approximately 1% in controls.	Glycine	36-39	thyrotropin releasing hormone	Mus musculus	31-34
12270926-8	2002	Levels of TRH-[Gly(4)] were depressed in homozygotes.	Glycine	15-18	thyrotropin releasing hormone	Mus musculus	10-13
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	65-68	carboxypeptidase E	Mus musculus	12-15
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	65-68	carboxypeptidase D	Mus musculus	19-37
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	65-68	thyrotropin releasing hormone	Mus musculus	60-63
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	64-68	carboxypeptidase E	Mus musculus	12-15
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	64-68	carboxypeptidase D	Mus musculus	19-37
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	64-68	thyrotropin releasing hormone	Mus musculus	60-63
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	89-92	carboxypeptidase E	Mus musculus	12-15
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	89-92	carboxypeptidase D	Mus musculus	19-37
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	89-92	thyrotropin releasing hormone	Mus musculus	84-87
12270926-11	2002	Recombinant CPE or carboxypeptidase D can convert synthetic TRH-[Gly(4)-Lys(5)] and TRH-[Gly(4)-Lys(5)-Arg(6)] to TRH-[Gly(4)].	Glycine	89-92	thyrotropin releasing hormone	Mus musculus	84-87
12459476-3	2002	Only the initial cleavage at Gly(35)-Ile(36) was dependent on MT1-MMP activity, as conversion to the active enzyme (Tyr(85) N-terminus) required a functional MMP-13 active site.	Glycine	29-32	matrix metallopeptidase 14 (membrane-inserted)	Mus musculus	62-69
12388176-7	2002	Glycine-gastrin antibody, indomethacin and nitro-l-arginine methyl ester had no effect.	Glycine	0-7	gastrin	Rattus norvegicus	8-15
12464013-2	2002	Previous work has shown that an FHA Arg-Gly-Asp (RGD, residues 1097-1099) site interacts with a complex composed of leucocyte response integrin (LRI, alphavbeta3 integrin) and integrin-associated protein (IAP, CD47) on human monocytes, resulting in enhancement of CR3-mediated bacterial binding.	Glycine	40-43	CD47 molecule	Homo sapiens	116-203
12464013-2	2002	Previous work has shown that an FHA Arg-Gly-Asp (RGD, residues 1097-1099) site interacts with a complex composed of leucocyte response integrin (LRI, alphavbeta3 integrin) and integrin-associated protein (IAP, CD47) on human monocytes, resulting in enhancement of CR3-mediated bacterial binding.	Glycine	40-43	CD47 molecule	Homo sapiens	205-208
12464013-2	2002	Previous work has shown that an FHA Arg-Gly-Asp (RGD, residues 1097-1099) site interacts with a complex composed of leucocyte response integrin (LRI, alphavbeta3 integrin) and integrin-associated protein (IAP, CD47) on human monocytes, resulting in enhancement of CR3-mediated bacterial binding.	Glycine	40-43	CD47 molecule	Homo sapiens	210-214
12117414-5	2002	In contrast, responses to a collagen-related peptide (CRP), made up of repeat glycine-proline-hydroxyproline motifs, were markedly inhibited and abolished in platelets expressing 50% and 20% of wild-type levels of GPVI respectively.	Glycine	78-85	C-reactive protein, pentraxin-related	Mus musculus	28-52
12117414-5	2002	In contrast, responses to a collagen-related peptide (CRP), made up of repeat glycine-proline-hydroxyproline motifs, were markedly inhibited and abolished in platelets expressing 50% and 20% of wild-type levels of GPVI respectively.	Glycine	78-85	C-reactive protein, pentraxin-related	Mus musculus	54-57
12213810-4	2002	The most dramatic loss of antigenicity was seen with the 17-kDa glycine decarboxylase complex (GDC) H-protein, which was correlated with the loss of glycine-dependent O2 consumption.	Glycine	64-71	myosin binding protein H	Homo sapiens	100-109
12372498-3	2002	Derivatization of the phenyl ring with a tripeptide Gly-Glu-Glu resulted in a potent, selective inhibitor against PTP1B.	Glycine	52-55	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	114-119
12401724-4	2002	We found that glycated LDL (gly-LDL) triggered STAT5 activation, the formation of a prolactin inducible element (PIE)-binding complex containing STAT5, and increased p21(waf) expression through the activation of the receptor for AGE (RAGE).	Glycine	14-17	long intergenic non-protein coding RNA 914	Homo sapiens	234-238
12401724-5	2002	We also demonstrated that dm-LDL and gly-LDL, but not n-LDL treatment induced the formation of a stable complex containing the activated STAT5 and RAGE.	Glycine	37-40	long intergenic non-protein coding RNA 914	Homo sapiens	147-151
12368313-6	2002	These results indicate that the fusion event mediated by the coexpression of gHL, gB, and gD in cells shares common features with the fusion of the virus envelope with the plasma membrane, they point to a likely role for the membrane-spanning and cytoplasmic tail domains of gH in both processes, and they suggest that a conserved glycine residue in the membrane-spanning sequence is crucial for efficient fusion.	Glycine	331-338	growth hormone 2	Homo sapiens	77-80
12161434-6	2002	Increases in cSHMT expression inhibit SAM concentrations by two proposed mechanisms: (1) cSHMT-catalyzed serine synthesis competes with the enzyme methylenetetrahydrofolate reductase for methylenetetrahydrofolate in a glycine-dependent manner, and (2) cSHMT, a high affinity 5-methyltetrahydrofolate-binding protein, sequesters this cofactor and inhibits methionine synthesis in a glycine-independent manner.	Glycine	218-225	methylenetetrahydrofolate reductase	Homo sapiens	147-182
12133828-11	2002	The data obtained from 14 new chimeras sustained that two nonadjacent pairs of amino acids, Gln(135) Thr(136) and Gly(140) Ser(141) in the C-terminal end of the N-terminal VPAC1 receptor ectodomain constitute a selective filter that strongly restricts access of secretin to the VPAC1 receptor.	Glycine	114-117	secretin	Homo sapiens	262-270
12392761-4	2002	The recombinant human ADAM-TS5, like ADAM-TS4 cleaves aggrecan at Glu(1480)-Gly(1481), Glu(1667)-Gly(1668), Glu(1771)-Ala(1772) and Glu(1871)-Leu(1872) bonds more readily than at the Glu(373)-Ala(374) bond.	Glycine	76-79	ADAM metallopeptidase with thrombospondin type 1 motif 5	Homo sapiens	22-30
12392761-4	2002	The recombinant human ADAM-TS5, like ADAM-TS4 cleaves aggrecan at Glu(1480)-Gly(1481), Glu(1667)-Gly(1668), Glu(1771)-Ala(1772) and Glu(1871)-Leu(1872) bonds more readily than at the Glu(373)-Ala(374) bond.	Glycine	97-100	ADAM metallopeptidase with thrombospondin type 1 motif 5	Homo sapiens	22-30
12392761-5	2002	In addition, ADAM-TS5 exhibited an additional site of cleavage in the region spanning residues Gly(1481) and Glu(1667), representing a unique cleavage of ADAM-TS5.	Glycine	95-98	ADAM metallopeptidase with thrombospondin type 1 motif 5	Homo sapiens	13-21
12500171-1	2002	OBJECTIVES: The content of C-Fos protein was tested in rat pinealocytes in the norm and stress and in case of intranasal administration of Epitalon (Ala-Glu-Asp-Gly), which regulated pineal secretion processes, presumably, via protooncogenes.	Glycine	161-164	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	27-32
12105201-4	2002	Three amino acids in the C terminus of P2X(4) (Tyr(378), Gly(381), and Leu(382)) compose a non-canonical tyrosine-based sorting signal of the form YXXGL.	Glycine	57-60	purinergic receptor P2X 4	Rattus norvegicus	39-45
12187102-11	2002	The plasma HGF concentration was equally elevated in treated and untreated Gly-ARF rats.	Glycine	75-78	hepatocyte growth factor	Rattus norvegicus	11-14
11931632-10	2002	Comparison of bovine and porcine OBP sequences pointed at OBPp glycine 121, in the hinge linking the beta-barrel to the alpha-helix.	Glycine	63-70	odorant-binding protein	Bos taurus	33-36
11931632-10	2002	Comparison of bovine and porcine OBP sequences pointed at OBPp glycine 121, in the hinge linking the beta-barrel to the alpha-helix.	Glycine	63-70	odorant-binding protein	Bos taurus	58-62
12123805-2	2002	To determine whether the RGD (Arg-Gly-Asp) motif of IGFBP-2 mediates cell surface binding in vivo, we mutated the RGD motif of IGFBP-2 into an RGE (Arg-Gly-Glu) sequence and produced transgenic mice (E mice) which express elevated amounts of mutated IGFBP-2.	Glycine	34-37	insulin-like growth factor binding protein 2	Mus musculus	52-59
12080445-3	2002	OBJECTIVE: To assess the effects of a polymorphism in codon 16 (Arg16--&gt;Gly) of the ADRB2 gene, which has been associated with a decrease in beta2-receptor density and efficiency, on longitudinal changes in obesity from childhood to young adulthood in a biracial cohort.	Glycine	75-78	adrenoceptor beta 2	Homo sapiens	87-92
12091465-3	2002	Functional analysis of the GFP-GLYT1 and GFP-GLYT2 stable cell lines demonstrated that they exhibited high affinity for glycine and the characteristic properties of both glycine transporter subtypes.	Glycine	120-127	solute carrier family 6 member 9	Rattus norvegicus	31-36
11925440-1	2002	Factor Xa (FXa) hydrolyzes two peptide bonds in prothrombin having (Glu/Asp)-Gly-Arg-(Thr/Ile) for P(3)-P(2)-P(1)-P(1)" residues, but the exact preferences of its catalytic groove remain largely unknown.	Glycine	77-80	coagulation factor X	Homo sapiens	0-9
11925440-1	2002	Factor Xa (FXa) hydrolyzes two peptide bonds in prothrombin having (Glu/Asp)-Gly-Arg-(Thr/Ile) for P(3)-P(2)-P(1)-P(1)" residues, but the exact preferences of its catalytic groove remain largely unknown.	Glycine	77-80	coagulation factor X	Homo sapiens	11-14
12009900-8	2002	Examination of various compounds with Ava in positions 9,10 and/or 14,15 revealed that the Leu(9)-Gly(10) and Arg(14)-Pro(15) segments of the disulfide ring are the principal structural elements determining hMCH-1R selectivity and ability to act as a hMCH-1R antagonist.	Glycine	98-101	CD7 molecule	Homo sapiens	91-96
11877399-1	2002	Serine hydroxymethyltransferase (SHMT), a member of the alpha-class of pyridoxal phosphate-dependent enzymes, catalyzes the reversible conversion of serine to glycine and tetrahydrofolate to 5,10-methylene tetrahydrofolate.	Glycine	159-166	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	33-37
11884718-3	2002	Here we report the crystal structure of the extracellular segment of integrin alphaVbeta3 in complex with a cyclic peptide presenting the Arg-Gly-Asp sequence.	Glycine	142-145	integrin subunit alpha V	Homo sapiens	69-89
11922676-4	2002	The sorcin monomer is organized in two domains like in all PEF proteins: a flexible, hydrophobic, glycine-rich N-terminal region and a calcium binding C-terminal domain.	Glycine	98-105	sorcin	Homo sapiens	4-10
11911775-5	2002	It has been suggested that these hydrophobic domains, predominantly containing glycine, proline, leucine and valine, often occurring in tandemly repeated sequences, are responsible for the ability of elastin to align monomeric chains for covalent cross-linking.	Glycine	79-86	elastin	Homo sapiens	200-207
11739383-12	2002	In addition, based upon the public data base, a single nucleotide polymorphism was found in the C terminus of HDAC10 which changes a Gly residue to Cys, suggesting that HDAC10 molecules containing these single nucleotide polymorphisms may be folded improperly.	Glycine	133-136	histone deacetylase 10	Homo sapiens	110-116
11739383-12	2002	In addition, based upon the public data base, a single nucleotide polymorphism was found in the C terminus of HDAC10 which changes a Gly residue to Cys, suggesting that HDAC10 molecules containing these single nucleotide polymorphisms may be folded improperly.	Glycine	133-136	histone deacetylase 10	Homo sapiens	169-175
11751879-9	2002	Our results demonstrate that Xaa-Arg-Gly sequences in the triple-helical procollagen molecule are dominant binding sites for HSP47 and enable us to predict HSP47-binding sites in homotrimeric procollagen molecules.	Glycine	37-40	serpin family H member 1	Homo sapiens	125-130
11751879-9	2002	Our results demonstrate that Xaa-Arg-Gly sequences in the triple-helical procollagen molecule are dominant binding sites for HSP47 and enable us to predict HSP47-binding sites in homotrimeric procollagen molecules.	Glycine	37-40	serpin family H member 1	Homo sapiens	156-161
11841215-2	2002	In wild-type (WT) BPTI, Gly 37 HN is in an unusual NH-aromatic-NH network of interactions with the ring of Tyr 35 and the side chain HN of Asn 44.	Glycine	24-27	spleen trypsin inhibitor I	Bos taurus	18-22
11841215-11	2002	The results illustrate the importance of the Gly-Gly sequence at positions 36 and 37 and the 37 HN-35 aromatic interaction to the stability, folding, and dynamics of the BPTI.	Glycine	45-48	spleen trypsin inhibitor I	Bos taurus	170-174
11841215-11	2002	The results illustrate the importance of the Gly-Gly sequence at positions 36 and 37 and the 37 HN-35 aromatic interaction to the stability, folding, and dynamics of the BPTI.	Glycine	49-52	spleen trypsin inhibitor I	Bos taurus	170-174
11841570-5	2002	Their rank order of potency in P2X4 and P2X7 receptors was carnosine = PA = His &gt; BPh &gt; Glycine (Gly) and carnosine = BPh = His &gt; PA &gt; Gly, respectively.	Glycine	94-101	purinergic receptor P2X 4	Rattus norvegicus	31-35
11841570-5	2002	Their rank order of potency in P2X4 and P2X7 receptors was carnosine = PA = His &gt; BPh &gt; Glycine (Gly) and carnosine = BPh = His &gt; PA &gt; Gly, respectively.	Glycine	94-97	purinergic receptor P2X 4	Rattus norvegicus	31-35
11841570-5	2002	Their rank order of potency in P2X4 and P2X7 receptors was carnosine = PA = His &gt; BPh &gt; Glycine (Gly) and carnosine = BPh = His &gt; PA &gt; Gly, respectively.	Glycine	103-106	purinergic receptor P2X 4	Rattus norvegicus	31-35
11841570-6	2002	The potency to prevent the zinc-induced potentiation in the P2X4 receptor was BPh &gt; PA &gt; His; carnosine, Gly and beta-alanine were inactive.	Glycine	111-114	purinergic receptor P2X 4	Rattus norvegicus	60-64
11790831-0	2002	An inducible helix-Gly-Gly-helix motif in the N-terminal domain of histone H1e: a CD and NMR study.	Glycine	19-22	H1.4 linker histone, cluster member	Mus musculus	67-78
11790831-0	2002	An inducible helix-Gly-Gly-helix motif in the N-terminal domain of histone H1e: a CD and NMR study.	Glycine	23-26	H1.4 linker histone, cluster member	Mus musculus	67-78
11843288-5	2002	Polymerase chain reaction revealed that the abnormal Hb was caused by a missense mutation within codon 83 of the beta-globin gene (GGC to GAC) resulting in a glycine-to-aspartic acid substitution, which corresponds to Hb Pyrgos.	Glycine	158-165	gamma-glutamylcyclotransferase	Homo sapiens	131-134
12392527-8	2002	The main enzyme cleavage sites were Lys-Trp, Val-Lys, Gly-Asp and Asp-Arg, as determined after incubation of P1 and P2 with the beta-chain of insulin.	Glycine	54-57	crystallin gamma F, pseudogene	Homo sapiens	109-118
11852566-1	2002	Inactivation of glucose 6-phosphate dehydrogenase (G6PDH) complexed with its substrate, glucose 6-phosphate (GP), and/or cofactor, NADP+, has been studied within the range 20-40 degrees C in three media: (a) 0.04 M NaOH-glycine buffer (pH 9.1); (b) Aerosol OT (AOT) reversed micelles in octane; and (c) Triton X-100 micelles in octane supplemented with 10% hexanol.	Glycine	220-227	glucose-6-phosphate dehydrogenase	Homo sapiens	16-49
11852566-1	2002	Inactivation of glucose 6-phosphate dehydrogenase (G6PDH) complexed with its substrate, glucose 6-phosphate (GP), and/or cofactor, NADP+, has been studied within the range 20-40 degrees C in three media: (a) 0.04 M NaOH-glycine buffer (pH 9.1); (b) Aerosol OT (AOT) reversed micelles in octane; and (c) Triton X-100 micelles in octane supplemented with 10% hexanol.	Glycine	220-227	glucose-6-phosphate dehydrogenase	Homo sapiens	51-56
12107963-1	2002	Lipoic acid is a prostetic group of H-protein of the glycine cleavage system and the dihydrolipoamide acyltransferases (E2) of the pyruvate, alpha-ketoglutarate and branched-chain alpha-keto acid dehydrogenase complexes.	Glycine	53-60	myosin binding protein H	Homo sapiens	36-45
11809931-4	2001	The CD2 variant with two Gly linkers has been shown to have the strongest metal binding affinity to Ca(II) and La(III).	Glycine	25-28	carbonic anhydrase 2	Homo sapiens	100-106
11745407-0	2001	Short term infusion of glycine-extended gastrin(17) stimulates both proliferation and formation of aberrant crypt foci in rat colonic mucosa.	Glycine	23-30	gastrin	Rattus norvegicus	40-47
11745407-3	2001	The aim of our study was to determine whether continuous systemic infusion of glycine-extended gastrin(17) stimulated proliferation and accelerated carcinogenesis in the colorectal mucosa.	Glycine	78-85	gastrin	Rattus norvegicus	95-102
11745407-8	2001	We conclude that short term administration of glycine-extended gastrin(17) to mature rats not only has a proliferative effect upon colonic mucosa, but also increases the number of aberrant crypt foci formed in the colorectal mucosa after treatment with azoxymethane.	Glycine	46-53	gastrin	Rattus norvegicus	63-70
11745407-9	2001	Glycine-extended gastrin(17) could thus potentially act as a promoter of carcinogenesis.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
11691584-3	2001	We have identified a novel missense mutation which substitutes a glycine for an aspartic acid residue in the thrombospondin (TSP) type 3 calcium-binding domain of COMP in a patient diagnosed with PSACH.	Glycine	65-72	cartilage oligomeric matrix protein	Homo sapiens	163-167
11557499-3	2001	TLE-1 differed from TEM-1 by a single Asp(115)--&gt;Gly substitution and has been renamed TEM-90.	Glycine	52-55	TLE family member 1, transcriptional corepressor	Homo sapiens	0-5
11564711-8	2001	However, it exhibited a higher ED(50) when compared to GLP-1 and GLP-1 Gly(8) (ED(50): GLP-1, 0.036 +/- 0.002 nM, GLP-1 Gly(8), 0.13 +/- 0.02 nM, GLP-1 Aha(8), 0.58 +/- 0.03 nM).	Glycine	71-74	glucagon	Rattus norvegicus	65-70
11564711-8	2001	However, it exhibited a higher ED(50) when compared to GLP-1 and GLP-1 Gly(8) (ED(50): GLP-1, 0.036 +/- 0.002 nM, GLP-1 Gly(8), 0.13 +/- 0.02 nM, GLP-1 Aha(8), 0.58 +/- 0.03 nM).	Glycine	71-74	glucagon	Rattus norvegicus	65-70
11564711-8	2001	However, it exhibited a higher ED(50) when compared to GLP-1 and GLP-1 Gly(8) (ED(50): GLP-1, 0.036 +/- 0.002 nM, GLP-1 Gly(8), 0.13 +/- 0.02 nM, GLP-1 Aha(8), 0.58 +/- 0.03 nM).	Glycine	71-74	glucagon	Rattus norvegicus	65-70
11564711-8	2001	However, it exhibited a higher ED(50) when compared to GLP-1 and GLP-1 Gly(8) (ED(50): GLP-1, 0.036 +/- 0.002 nM, GLP-1 Gly(8), 0.13 +/- 0.02 nM, GLP-1 Aha(8), 0.58 +/- 0.03 nM).	Glycine	71-74	glucagon	Rattus norvegicus	65-70
11454468-0	2001	Discovery and SAR of org 24598-a selective glycine uptake inhibitor.	Glycine	43-50	sarcosine dehydrogenase	Homo sapiens	14-17
11473485-5	2001	We have made mutations to one of the most highly conserved residues of the pore, glycine-143, of the inward rectifier ROMK1 (Kir1.1), and examined the resulting channel properties in the Xenopus oocyte expression system with a two-electrode voltage clamp.	Glycine	81-88	potassium inwardly rectifying channel subfamily J member 1 S homeolog	Xenopus laevis	118-123
11473485-5	2001	We have made mutations to one of the most highly conserved residues of the pore, glycine-143, of the inward rectifier ROMK1 (Kir1.1), and examined the resulting channel properties in the Xenopus oocyte expression system with a two-electrode voltage clamp.	Glycine	81-88	potassium inwardly rectifying channel subfamily J member 1 S homeolog	Xenopus laevis	125-131
11580269-4	2001	When two evolutionarily highly conserved glycine residues of beta-actin, G146 and G150, were changed to proline, both mutant actin proteins were poorly processed by CCT in in vitro translation assays; they become arrested on CCT.	Glycine	41-48	POTE ankyrin domain family member F	Homo sapiens	61-71
11509230-6	2001	SMN interaction requires the arginine- and glycine-rich domains of both fibrillarin and GAR1 and is defective in SMN mutants found in some SMA patients.	Glycine	43-50	fibrillarin	Homo sapiens	72-83
11509230-6	2001	SMN interaction requires the arginine- and glycine-rich domains of both fibrillarin and GAR1 and is defective in SMN mutants found in some SMA patients.	Glycine	43-50	GAR1 ribonucleoprotein	Homo sapiens	88-92
11389857-2	2001	SMN binds the arginine- and glycine-rich (RG) domains of the snRNP proteins SmD1 and SmD3.	Glycine	28-35	small nuclear ribonucleoprotein D1 polypeptide	Homo sapiens	76-80
11278406-5	2001	By expressing functional chimeras between KCNQ1 and KCNQ2 in Xenopus oocytes, we mapped the region of this inactivation to transmembrane domain S5 and the pore loop H5 and finally narrowed down the site to positions Gly(272) and Val(307) in KCNQ1.	Glycine	216-219	potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog	Xenopus laevis	42-47
11256966-8	2001	End-terminal sequence analysis of the soluble betaglycan showed that Gly(24) is the first residue of the mature protein.	Glycine	69-72	transforming growth factor beta receptor 3	Homo sapiens	46-56
11430426-4	2001	The two 699 amino acid predicted protein sequences differ in two residues at positions 341 (Gly or Cys within the repression domain) and 448 (Pro or Ser) and show over 80, 70 and 60% homology to maize, rice and oat VP1 proteins respectively.	Glycine	92-95	regulatory protein viviparous-1	Zea mays	215-218
11401448-4	2001	CNRc1 and c2 lack the Arg-Gly-Asp (RGD) sequence that is conserved in the EC1 of CNR1-8, which is necessary for binding to Reelin.	Glycine	26-29	reelin	Homo sapiens	123-129
11160737-3	2001	Expression in HeLa T4 cells of a mutant Env protein with a single Gly insertion after I619, five amino acids upstream from the R peptide, induced syncytium formation with overlaid XC cells.	Glycine	66-69	endogenous retrovirus group K member 20	Homo sapiens	40-43
11160737-4	2001	Env proteins containing single or double Gly-Ser insertions after F614, 10 amino acids upstream from the R peptide, induced syncytium formation, and mutant proteins with multiple Gly insertions induced various levels of syncytium formation between HeLa T4 and XC cells.	Glycine	41-44	endogenous retrovirus group K member 20	Homo sapiens	0-3
11179971-4	2001	To understand if its elastolytic activity results from a preference for glycine-rich substrates, we studied its ability to hydrolyse the 65 pentapeptides of human tropoelastin containing at least three glycines.	Glycine	202-210	elastin	Homo sapiens	163-175
11156646-1	2001	BACKGROUND: Kirsten ras (Ki-ras) mutations are common in gastrointestinal cancer and one codon 12 mutation, glycine to valine, is particularly aggressive in colorectal cancer.	Glycine	108-115	KRAS proto-oncogene, GTPase	Homo sapiens	12-23
11156646-1	2001	BACKGROUND: Kirsten ras (Ki-ras) mutations are common in gastrointestinal cancer and one codon 12 mutation, glycine to valine, is particularly aggressive in colorectal cancer.	Glycine	108-115	KRAS proto-oncogene, GTPase	Homo sapiens	25-31
11161025-1	2001	The glycine-rich structural protein GRP1.8 of French bean (Phaseolus vulgaris) is specifically localized in the modified primary cell walls of protoxylem elements.	Glycine	4-11	glycine-rich RNA-binding protein-like	Nicotiana tabacum	36-40
11123201-3	2001	Pancreatic fluid secretion was increased equipotently by secretin and secretin-Gly, but secretin was markedly more potent for inhibition of basal and gastrin-induced acid secretion.	Glycine	79-82	secretin	Rattus norvegicus	70-78
11123201-3	2001	Pancreatic fluid secretion was increased equipotently by secretin and secretin-Gly, but secretin was markedly more potent for inhibition of basal and gastrin-induced acid secretion.	Glycine	79-82	secretin	Rattus norvegicus	70-78
11123201-6	2001	Thus the equipotent actions of secretin and secretin-Gly on pancreatic secretion appear to result from equal binding and activation of the pancreatic secretin receptor.	Glycine	53-56	secretin	Rattus norvegicus	44-52
11167698-0	2001	Generalized dystrophic epidermolysis bullosa: identification of a novel, homozygous glycine substitution, G2031S, in exon 73 of COL7A1 in monozygous triplets.	Glycine	84-91	collagen type VII alpha 1 chain	Homo sapiens	128-134
11167698-4	2001	Mutation analysis in this family revealed a novel recessively expressed glycine substitution, G2031S, in exon 73 of the collagen VII gene COL7A1.	Glycine	72-79	collagen type VII alpha 1 chain	Homo sapiens	138-144
11306963-7	2001	Subjects homozygous for glycine at beta(2)-AR-16 showed no such decline.	Glycine	24-31	adrenoceptor beta 2	Homo sapiens	35-45
11396606-6	2001	It is believed that the termination of the different synaptic actions of glycine is produced by rapid re-uptake through two sodium-and-chloride-coupled transporters, GLYT1 and GLYT2, located in the plasma membrane of glial cells or pre-synaptic terminals, respectively.	Glycine	73-80	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	176-181
11738262-3	2001	Glycine- and GABA(A)-activated currents were demonstrated during applications of glycine and GABA (50-100 microM) in 5 days in vitro (DIV) neurons.	Glycine	81-88	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	13-20
11738262-14	2001	This suggests that glycine and GABA(A) receptors provide a fundamental regulation of both neuronal excitability and intracellular Ca(2+) at this early time of development.The neurotrophic effects of agonists and antagonists for glycine, GABA(A) and glutamate receptors were examined in neurons cultured for 2 or 5 DIV.	Glycine	19-26	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	237-244
11738262-14	2001	This suggests that glycine and GABA(A) receptors provide a fundamental regulation of both neuronal excitability and intracellular Ca(2+) at this early time of development.The neurotrophic effects of agonists and antagonists for glycine, GABA(A) and glutamate receptors were examined in neurons cultured for 2 or 5 DIV.	Glycine	228-235	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	31-38
11071770-2	2000	Mass spectrometry analysis of this protein indicated the presence of a glycine-rich domain homologous to human keratin 9 (K9).	Glycine	71-78	keratin 9	Homo sapiens	111-120
11071770-2	2000	Mass spectrometry analysis of this protein indicated the presence of a glycine-rich domain homologous to human keratin 9 (K9).	Glycine	71-78	keratin 9	Homo sapiens	122-124
11041849-9	2000	The minor conformer (trans peptide bond) forms a hairpin structure with sheetlike hydrogen bonds and a type II beta-turn, with the D-Trp4 at the "Gly position" of the turn.	Glycine	146-149	transient receptor potential cation channel subfamily C member 4	Homo sapiens	133-137
11106095-11	2000	In eight cases (89%), the mutations of the K-ras codon 12 were of the same type: GGT (glycine) to GTT (valine).	Glycine	86-93	KRAS proto-oncogene, GTPase	Homo sapiens	43-48
11112510-3	2000	In HSL this dipeptide is followed by two additional glycine residues.	Glycine	52-59	lipase E, hormone sensitive type	Homo sapiens	3-6
10970296-10	2000	So, by choosing the appropriate route, isoxazolidinyl analogues having either syn or anti configuration with respect to the glycine unit can be prepared in enantiomerically pure form.	Glycine	124-131	synemin	Homo sapiens	78-81
10969139-7	2000	By using potent GRP/bombesin receptor antagonists, we showed that this synthetic glycine-extended bombesin analogue induces its biological activities via the classical GRP/bombesin receptor.	Glycine	81-88	gastrin releasing peptide	Rattus norvegicus	16-19
10969139-7	2000	By using potent GRP/bombesin receptor antagonists, we showed that this synthetic glycine-extended bombesin analogue induces its biological activities via the classical GRP/bombesin receptor.	Glycine	81-88	gastrin releasing peptide	Rattus norvegicus	168-171
10942404-8	2000	Three of the point mutations, in 3 patients, resulted in FECH variants with 2 of the [2Fe-2S] cluster cysteines substituted with tyrosine, serine, and glycine (ie, C406Y, C406S, and C411G) and with undetectable enzymatic activity.	Glycine	151-158	ferrochelatase	Homo sapiens	57-61
10924333-0	2000	The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein (CRP2BP).	Glycine	18-25	cysteine rich protein 2	Homo sapiens	50-54
10967152-0	2000	Effects of adding a leukotriene antagonist or a long-acting beta(2)-agonist in asthmatic patients with the glycine-16 beta(2)-adrenoceptor genotype.	Glycine	107-114	adrenoceptor beta 2	Homo sapiens	118-138
10967152-1	2000	PURPOSE: In the United Kingdom, about 40% of patients with asthma are homozygous for the glycine-16 beta(2)-adrenoceptor polymorphism, which predisposes them to agonist-induced down-regulation and desensitization of the beta(2)-adrenoceptor.	Glycine	89-96	adrenoceptor beta 2	Homo sapiens	100-120
10967152-1	2000	PURPOSE: In the United Kingdom, about 40% of patients with asthma are homozygous for the glycine-16 beta(2)-adrenoceptor polymorphism, which predisposes them to agonist-induced down-regulation and desensitization of the beta(2)-adrenoceptor.	Glycine	89-96	adrenoceptor beta 2	Homo sapiens	220-240
10938011-9	2000	In vitro studies of the function of NOV protein showed that it promoted VSMC adhesion via a mechanism that was divalent cation and Arg-Gly-Asp independent but that it did not modulate VSMC proliferation or phenotype.	Glycine	135-138	cellular communication network factor 3	Rattus norvegicus	36-39
10936119-0	2000	Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism.	Glycine	101-108	adrenoceptor beta 2	Homo sapiens	112-132
10936119-2	2000	The homozygous glycine-16 polymorphism of the beta(2)-adrenoceptor occurs in approximately 40% of patients and is known to predispose to agonist-induced downregulation and desensitization.	Glycine	15-22	adrenoceptor beta 2	Homo sapiens	46-66
10806190-9	2000	The interaction between yUbc9 and SUMO-1 was abolished by deleting the C-terminal Gly residue of SUMO-1, which is reportedly required for the formation of Ubc9-SUMO-1 thioester linkage.	Glycine	82-85	ubiquitin-conjugating enzyme E2I	Mus musculus	25-29
10903223-8	2000	There was no decline in peak flow with regular use of albuterol in patients who were homozygous for glycine at beta(2)-AR-16.	Glycine	100-107	adrenoceptor beta 2	Homo sapiens	111-121
10749851-9	2000	Deletion studies demonstrated that the COOH-terminal region of ILF3, which is rich in arginine, glycine, and serine, is responsible for the strong interaction between PRMT1 and ILF3 and is the site of ILF3 methylation by PRMT1.	Glycine	96-103	protein arginine methyltransferase 1	Homo sapiens	167-172
10749851-9	2000	Deletion studies demonstrated that the COOH-terminal region of ILF3, which is rich in arginine, glycine, and serine, is responsible for the strong interaction between PRMT1 and ILF3 and is the site of ILF3 methylation by PRMT1.	Glycine	96-103	protein arginine methyltransferase 1	Homo sapiens	221-226
10748206-5	2000	In PTPalpha, this residue is a glutamine causing steric hindrance and in PTP1B a glycine allowing broad substrate recognition.	Glycine	81-88	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	73-78
10856217-1	2000	Mutations introduced into human growth hormone (hGH) (Thr175 --&gt; Gly-hGH) and the extracellular domain of the hGH receptor (Trp104 --&gt; Gly-hGHbp) created a cavity at the protein-protein interface that resulted in binding affinity being reduced by a factor of 10(6).	Glycine	141-144	growth hormone receptor	Homo sapiens	113-125
10856217-1	2000	Mutations introduced into human growth hormone (hGH) (Thr175 --&gt; Gly-hGH) and the extracellular domain of the hGH receptor (Trp104 --&gt; Gly-hGHbp) created a cavity at the protein-protein interface that resulted in binding affinity being reduced by a factor of 10(6).	Glycine	141-144	growth hormone receptor	Homo sapiens	145-150
10886333-3	2000	Glycine-triggered Ca2+ influx in OP cells actually results from an initial depolarization that is the consequence of the activation of both the ionotropic glycine receptor (GlyR) and Na+-dependent transporters, most probably the glycine transporters 1 (GLYT1) and/or 2 (GLYT2) which are colocalized in these cells.	Glycine	0-7	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	270-275
10826481-2	2000	Additional mutagenesis indicates that important residues in this region for CCR5 binding are Ile-420, Lys-421, Gln-422, Pro-438, and Gly-441.	Glycine	133-136	C-C motif chemokine receptor 5	Homo sapiens	76-80
10744740-8	2000	An unlinked suppressor gene, ASC1 (alpha-subunit complementing) of the atp1-2 mutation (Gly(291) --&gt; Asp) restored the growth defect phenotype on glycerol, but did not suppress either atp1-1 or the deletion mutant Deltaatp1.	Glycine	88-91	guanine nucleotide-binding protein subunit beta	Saccharomyces cerevisiae S288C	29-33
10744740-8	2000	An unlinked suppressor gene, ASC1 (alpha-subunit complementing) of the atp1-2 mutation (Gly(291) --&gt; Asp) restored the growth defect phenotype on glycerol, but did not suppress either atp1-1 or the deletion mutant Deltaatp1.	Glycine	88-91	F1F0 ATP synthase subunit beta	Saccharomyces cerevisiae S288C	71-77
10766139-5	2000	CONCLUSION: Administration of endothelin-1 to the microvasculature of the optic nerve leads to elevation of glutamate, aspartate, and glycine concentrations in the vitreous.	Glycine	134-141	endothelin-1	Oryctolagus cuniculus	30-42
10739955-5	2000	Amino acid number 12 of K-Ras (wild type; Gly) was changed to Ser, Arg, Cys, Asp, Ala, or Val, and the mobility shift of the greenish fluorescent bands in the SDS/urea gel was analyzed.	Glycine	42-45	KRAS proto-oncogene, GTPase	Homo sapiens	24-29
10722844-3	2000	Co-transfection of syntaxin 1A with GLYT1 or GLYT2 in COS cells resulted in approximately 40% inhibition in glycine transport.	Glycine	108-115	solute carrier family 6 member 9	Rattus norvegicus	36-41
10716626-2	2000	Threonine aldolase catalyzes the pyridoxal phosphate-dependent, reversible reaction between threonine and acetaldehyde plus glycine.	Glycine	124-131	serine hydroxymethyltransferase 2	Homo sapiens	0-18
10752624-5	2000	On the other hand, the Y99L mutation has no effect on the activity of tPA toward the natural substrate plasminogen, that carries Gly at P2, and reduces more than 10-fold the inhibition of tPA by plasminogen activator inhibitor-1 (PAI-1), that carries Ala at P2.	Glycine	129-132	chromosome 20 open reading frame 181	Homo sapiens	188-191
10666288-1	2000	Bifunctional peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes the copper-, ascorbate-, and O(2)-dependent cleavage of C-terminal glycine-extended peptides and N-acylglycines to the corresponding amides and glyoxylate.	Glycine	21-28	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	60-63
10666288-3	2000	Bile acid glycine conjugates are also substrates for PAM leading to the formation of bile acid amides.	Glycine	10-17	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	53-56
10666288-4	2000	The (V(MAX)/K(m))(app) values for the bile acid glycine conjugates are comparable to other known PAM substrates.	Glycine	48-55	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	97-100
10648402-2	2000	The vWf-binding site on GP Ib-IX-V is within the N-terminal 282 residues of GP Ibalpha, which consist of an N-terminal flanking sequence (His-1-Ile-35), 7 leucine-rich repeats (Leu-36-Ala-200), a C-terminal flank (Phe-201-Gly-268), and a sulfated tyrosine sequence (Asp-269-Glu-282).	Glycine	222-225	glycoprotein Ib platelet subunit alpha	Homo sapiens	76-86
10607477-11	1999	In the placenta, mSHMT may be important for glycine production from serine.	Glycine	44-51	serine hydroxymethyltransferase 1 (soluble)	Mus musculus	17-22
10514515-2	1999	Here, we report the identification in human erythroblasts of a novel cDNA, designated HUT11A, which encodes a protein identical to the previously reported erythroid HUT11 urea transporter, except for a Lys(44) --&gt; Glu substitution and a Val-Gly dipeptide deletion after proline 227, which leads to a polypeptide of 389 residues versus 391 in HUT11.	Glycine	244-247	solute carrier family 14 member 1 (Kidd blood group)	Homo sapiens	86-91
10514515-2	1999	Here, we report the identification in human erythroblasts of a novel cDNA, designated HUT11A, which encodes a protein identical to the previously reported erythroid HUT11 urea transporter, except for a Lys(44) --&gt; Glu substitution and a Val-Gly dipeptide deletion after proline 227, which leads to a polypeptide of 389 residues versus 391 in HUT11.	Glycine	244-247	solute carrier family 14 member 1 (Kidd blood group)	Homo sapiens	165-170
10514515-3	1999	Genomic typing by polymerase chain reaction and transcript analysis by ribonuclease protection assay demonstrated that HUT11A encodes the true Kidd blood group/urea transporter protein, which carries only 2 Val-Gly motifs.	Glycine	211-214	solute carrier family 14 member 1 (Kidd blood group)	Homo sapiens	143-159
10400884-5	1999	HyA strands were crosslinked by glutaraldehyde and then resurfaced with poly-D-lysine, poly-L-lysine, glycine, or glutamine.	Glycine	102-109	lysine demethylase 5D	Homo sapiens	0-3
10518318-0	1999	Arginine methylation of a glycine and arginine rich peptide derived from sequences of human FMRP and fibrillarin.	Glycine	26-33	fibrillarin	Homo sapiens	101-112
10498402-2	1999	In this study, we examined the relationship of a polymorphism (2756A--&gt;G, asp--&gt;gly) in the gene (MTR) for methionine synthase, another important enzyme in the same folate/methionine/homocyst(e)ine metabolic pathway, with risk of colorectal cancer among 356 cases and 476 cancer-free controls.	Glycine	86-89	5-methyltetrahydrofolate-homocysteine methyltransferase	Homo sapiens	113-132
10498402-6	1999	However, similar to the interaction observed for the MTHFR polymorphism among men who consumed less than 1 alcoholic drink/day, those with the gly/gly genotype had a lower risk of colorectal cancer with an odds ratio of 0.27 (95% CI, 0.09-0.81) compared with those with the asp/asp genotype.	Glycine	143-146	methylenetetrahydrofolate reductase	Homo sapiens	53-58
10469344-0	1999	Compound heterozygosity for silent and dominant glycine substitution mutations in COL7A1 leads to a marked transient intracytoplasmic retention of procollagen VII and a moderately severe dystrophic epidermolysis bullosa phenotype.	Glycine	48-55	collagen type VII alpha 1 chain	Homo sapiens	82-88
10463479-5	1999	All of the K-ras mutations were G-to-A transition mutations in the second position of codon 13 (glycine --&gt; aspartic acid).	Glycine	96-103	KRAS proto-oncogene, GTPase	Homo sapiens	11-16
10094940-5	1999	In addition, another lipoic binding protein, the H-protein of the glycine cleavage complex, was also studied as a potential autoantigen recognized by AMA.	Glycine	66-73	myosin binding protein H	Homo sapiens	49-58
10192449-6	1999	G6PD Orissa (nt 131 G--&gt;C; residue 44 Ala--&gt;Gly) was found to be the most common variant among Indo-Mauritians: this deficient variant was recently identified to be highly characteristic of the tribal groups in central India.	Glycine	50-53	glucose-6-phosphate dehydrogenase	Homo sapiens	0-4
10367958-2	1999	In all species, all glycine-containing amacrine cells expressed immunoreactivity for glyt-1, though the intensity of immunoreactivity for glyt-1 did not appear to directly correlate with the intensity of immunoreactivity for glycine in individual cells.	Glycine	20-27	solute carrier family 6 member 9	Rattus norvegicus	85-91
10367958-3	1999	A small subpopulation of glycine-immunoreactive displaced amacrine cells or ganglion cells also expressed glyt-1 in retinae from macaques, cats, chickens, and rats but not in retinae from rabbits.	Glycine	25-32	solute carrier family 6 member 9	Rattus norvegicus	106-112
10367958-5	1999	In monkeys, cats, and rats, populations of cells which we interpret as being glycine-containing interplexiform cells expressed glyt-1: these cells lacked a content of glutamate, suggesting they are not bipolar cells.	Glycine	77-84	solute carrier family 6 member 9	Rattus norvegicus	127-133
9988730-4	1999	Mutation at Gly-306 of 70Z disrupted its association with Zap-70 and almost completely abolished its ability to induce NFAT activation under basal and ionomycin-stimulated conditions.	Glycine	12-15	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	58-64
9933163-2	1999	When fluid containing glycine repeatedly circulated through the hot and cold regions in the reactor, oligopeptides were made from glycine.	Glycine	22-29	alcohol dehydrogenase iron containing 1	Homo sapiens	64-67
9989851-9	1999	Genetic analysis using polymerase chain reaction with mutant enrichment and allele specific oligonucleotide hybridization detected a single mutation at codon 12 of K-ras, which changed the wild-type glycine to arginine.	Glycine	199-206	KRAS proto-oncogene, GTPase	Homo sapiens	164-169
9932724-4	1999	This study examines the effects on histamine release from the vascularly perfused rat stomach of amidated gastrin-17, COOH-terminal glycine-extended gastrin-17, gastrin-17 extended at the COOH-terminal including the remaining progastrin sequence, and carboxy-terminal progastrin fragments (SAEDEN and GRRSAEDEN).	Glycine	132-139	gastrin	Rattus norvegicus	149-156
10195445-4	1999	Deletion of the Gly-Ile-Gly sequence, the central hinge region of L-CA-MA, produced a considerable reduction in antitumor and hemolytic activity rather than an antibacterial one.	Glycine	16-19	protein tyrosine phosphatase receptor type C	Homo sapiens	66-70
10195445-4	1999	Deletion of the Gly-Ile-Gly sequence, the central hinge region of L-CA-MA, produced a considerable reduction in antitumor and hemolytic activity rather than an antibacterial one.	Glycine	24-27	protein tyrosine phosphatase receptor type C	Homo sapiens	66-70
11624203-11	1999	A molecular study of the neoplastic tissue evidenced a typical mutation of the K-ras gene codon 12:the normal sequence GGT (glycine) was altered into GAT (aspartic acid).	Glycine	124-131	KRAS proto-oncogene, GTPase	Homo sapiens	79-84
10553678-4	1999	In this experiment, the structural gene, cofP, encoding CFA/III prepilin peptidase which cleavages at the Gly-30-Met-31 junction of CofA was identified, and the nucleotide sequence of the gene was determined.	Glycine	106-109	tubulin folding cofactor A	Homo sapiens	56-63
9847294-7	1998	We observed that the ADRB2 haplotype with a Gly at position 16 and a Gln at position 27 is associated with BHR in our sample.	Glycine	44-47	adrenoceptor beta 2	Homo sapiens	21-26
10221600-0	1998	Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK: identification of CCK 8 Gly as the immediate precursor of CCK 8 in rodent brain.	Glycine	132-139	carboxypeptidase E	Mus musculus	6-24
10221600-0	1998	Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK: identification of CCK 8 Gly as the immediate precursor of CCK 8 in rodent brain.	Glycine	191-194	carboxypeptidase E	Mus musculus	6-24
10221600-0	1998	Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK: identification of CCK 8 Gly as the immediate precursor of CCK 8 in rodent brain.	Glycine	191-194	cholecystokinin	Mus musculus	162-165
10221600-0	1998	Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK: identification of CCK 8 Gly as the immediate precursor of CCK 8 in rodent brain.	Glycine	191-194	cholecystokinin	Mus musculus	162-165
10221600-0	1998	Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK: identification of CCK 8 Gly as the immediate precursor of CCK 8 in rodent brain.	Glycine	191-194	cholecystokinin	Mus musculus	162-165
9880037-3	1998	This variant contains only three instead of the usual five copies of a short peptide repeat [Pro-Gln/His-Gly-Gly-Gly-(Gly)-TrpGly-Gln] characteristic of PrP, with an additional Trp to Gly substitution in codon 102.	Glycine	105-108	major prion protein	Capra hircus	153-156
9880037-3	1998	This variant contains only three instead of the usual five copies of a short peptide repeat [Pro-Gln/His-Gly-Gly-Gly-(Gly)-TrpGly-Gln] characteristic of PrP, with an additional Trp to Gly substitution in codon 102.	Glycine	109-112	major prion protein	Capra hircus	153-156
9880037-3	1998	This variant contains only three instead of the usual five copies of a short peptide repeat [Pro-Gln/His-Gly-Gly-Gly-(Gly)-TrpGly-Gln] characteristic of PrP, with an additional Trp to Gly substitution in codon 102.	Glycine	109-112	major prion protein	Capra hircus	153-156
9880037-3	1998	This variant contains only three instead of the usual five copies of a short peptide repeat [Pro-Gln/His-Gly-Gly-Gly-(Gly)-TrpGly-Gln] characteristic of PrP, with an additional Trp to Gly substitution in codon 102.	Glycine	118-122	major prion protein	Capra hircus	153-156
9856843-0	1998	Novel and de novo glycine substitution mutations in the type VII collagen gene (COL7A1) in dystrophic epidermolysis bullosa: implications for genetic counseling.	Glycine	18-25	collagen type VII alpha 1 chain	Homo sapiens	80-86
9856844-5	1998	We now report a TBDN patient who is compound heterozygous for a recessive and a dominant glycine substitution mutation in COL7A1.	Glycine	89-96	collagen type VII alpha 1 chain	Homo sapiens	122-128
9843209-7	1998	We detected heterozygous missense mutations in GJB3 in four EKV families leading to substitution of a conserved glycine by charged residues (G12R and G12D), or change of a cysteine (C86S).	Glycine	112-119	gap junction protein beta 3	Homo sapiens	47-51
9806894-2	1998	The amide functions are introduced by the sequential actions of peptidylglycine alpha-hydroxylating mono-oxygenase (PHM; EC 1.14.17.3) and peptidylamidoglycollate lyase (PAL; EC 4.3.2.5) from their glycine-extended precursors.	Glycine	72-79	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	116-119
9806894-2	1998	The amide functions are introduced by the sequential actions of peptidylglycine alpha-hydroxylating mono-oxygenase (PHM; EC 1.14.17.3) and peptidylamidoglycollate lyase (PAL; EC 4.3.2.5) from their glycine-extended precursors.	Glycine	72-79	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	170-173
9806894-11	1998	The large Dk indicated that the glycine hydroxylation catalysed by PHM might proceed in a stepwise mechanism similar to that proposed for the dopamine beta-hydroxylase reaction [Miller and Klinman (1983) Biochemistry 22, 3091-3096].	Glycine	32-39	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	67-70
9799553-1	1998	Metacresol and glycine can be thought as a dissection of metatyrosine, which is an excellent substrate of phenylalanine ammonia-lyase (PAL) (B. Schuster and J. Retey, PNAS 92, 8433, 1995).	Glycine	15-22	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	106-133
9799553-1	1998	Metacresol and glycine can be thought as a dissection of metatyrosine, which is an excellent substrate of phenylalanine ammonia-lyase (PAL) (B. Schuster and J. Retey, PNAS 92, 8433, 1995).	Glycine	15-22	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	135-138
9842991-2	1998	We detected associations between PON2 variation in codon 148 (Ala --&gt; Gly) and variation in fasting plasma concentrations of total and low-density lipoprotein (LDL) cholesterol and apolipoprotein (apo) B.	Glycine	73-76	paraoxonase 2	Homo sapiens	33-37
9786934-3	1998	hnRNP D and nucleolin both contain canonical RNA binding domains (RBDs also called RRMs) and Arg-Gly-Gly (RGG) motifs.	Glycine	97-100	heterogeneous nuclear ribonucleoprotein D	Homo sapiens	0-7
9786934-3	1998	hnRNP D and nucleolin both contain canonical RNA binding domains (RBDs also called RRMs) and Arg-Gly-Gly (RGG) motifs.	Glycine	101-104	heterogeneous nuclear ribonucleoprotein D	Homo sapiens	0-7
9795213-6	1998	The RBP56/hTAFII68, FUS/TLS and EWS proteins comprise a sub-family of RNA binding proteins, which consist of an N-terminal Ser, Gly, Gln and Tyr-rich region, an RNA binding domain, a Cys2/Cys2 zinc finger motif and a C-terminal RGG-containing region.	Glycine	128-131	TATA-box binding protein associated factor 15	Homo sapiens	4-9
9795213-6	1998	The RBP56/hTAFII68, FUS/TLS and EWS proteins comprise a sub-family of RNA binding proteins, which consist of an N-terminal Ser, Gly, Gln and Tyr-rich region, an RNA binding domain, a Cys2/Cys2 zinc finger motif and a C-terminal RGG-containing region.	Glycine	128-131	TATA-box binding protein associated factor 15	Homo sapiens	10-18
9795236-7	1998	p45 contains an N-terminal FG (Phe-Gly) repeat region, a middle coiled-coil region, and a truncated C-terminal FG repeat region (compared to p58).	Glycine	35-38	caspase 1	Rattus norvegicus	0-3
9748272-4	1998	These cells were found to have two point mutations in the reduced folate carrier (RFC), resulting in a replacement of isoleucine 48 by phenylalanine and of tryptophan 105 by glycine.	Glycine	174-181	solute carrier family 19 (folate transporter), member 1	Mus musculus	58-80
9748272-4	1998	These cells were found to have two point mutations in the reduced folate carrier (RFC), resulting in a replacement of isoleucine 48 by phenylalanine and of tryptophan 105 by glycine.	Glycine	174-181	solute carrier family 19 (folate transporter), member 1	Mus musculus	82-85
9758163-4	1998	In the absence of NMDA, glycine increased on its own and in a concentration-dependent manner the depolarization-evoked release of both CCK-LI and SRIF-LI.	Glycine	24-31	cholecystokinin	Rattus norvegicus	135-138
9758163-8	1998	It is concluded that nerve terminals of CCK- and SRIF-releasing neurons possess non-conventional NMDA receptors whose channels can be operated by glycine or D-serine without apparent activation of the glutamatergic coagonist site.	Glycine	146-153	cholecystokinin	Rattus norvegicus	40-43
9749667-3	1998	Analysis of three genes required for synthesis of glutamine, glycine and 10-formyl tetrahydrofolate (GLN1, SHM2 and MTD1, respectively) shows that their expression is repressed by adenine and requires the transcription factors Baslp and Bas2p.	Glycine	61-68	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	107-111
9660765-2	1998	ZFM1 was shown to interact with and repress transcription from the glycine, glutamine, serine, and threonine-rich transcription activation domain of the sea urchin transcription factor, stage-specific activator protein (SSAP).	Glycine	67-74	splicing factor 1	Homo sapiens	0-4
9624125-6	1998	Replacement of Gly-430 in MDEG1 by bulkier amino acids, such as Val, Phe, or Thr, drastically increases the H+ sensitivity of the channel (half-maximal pH (pHm) approximately 4.4 for MDEG1, pHm approximately 6.7 for the different mutants).	Glycine	15-18	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	156-159
9624125-6	1998	Replacement of Gly-430 in MDEG1 by bulkier amino acids, such as Val, Phe, or Thr, drastically increases the H+ sensitivity of the channel (half-maximal pH (pHm) approximately 4.4 for MDEG1, pHm approximately 6.7 for the different mutants).	Glycine	15-18	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	190-193
9609684-12	1998	A single Gly (121) insertion was found in OBPp when it was compared to OBPb, which may prevent domain swapping from taking place.	Glycine	9-12	odorant-binding protein	Bos taurus	42-46
9657396-0	1998	Role of two conserved glycine residues in the beta-propeller domain of the integrin alpha4 subunit in VLA-4 conformation and function.	Glycine	22-29	immunoglobulin binding protein 1	Homo sapiens	84-90
9585570-1	1998	Characterization by kinetic and equilibrium methods of the interactions of cystatin A Gly-4 mutants with papain, cathepsin B, and cathepsin L.	Glycine	86-89	cathepsin B	Homo sapiens	113-124
9583604-5	1998	RESULTS: In 22 (41%) out of 54 subtype B sequences from heterosexually infected individuals, the synonymous nucleotide substitution in the second glycine codon at the tip of the V3 loop (the GGC pattern), previously identified as specific for Dutch injecting drug users (IDU), was found.	Glycine	146-153	gamma-glutamylcyclotransferase	Homo sapiens	191-194
9551389-8	1998	In one of the three families there is a point mutation in exon 20 causing an arginine to glycine change, which is likely to alter structure and hence function of the factor H protein.	Glycine	89-96	complement factor H	Homo sapiens	166-174
9506532-2	1998	The immunogen Gastrimmune is composed of the amino terminus of gastrin-17 linked to diphtheria toxoid and raises antibodies in situ which neutralise amidated and glycine-extended gastrin-17.	Glycine	162-169	gastrin	Rattus norvegicus	179-186
9546654-6	1998	Pharmacological characterization of crude membrane preparations of the recombinant yeast cells showed saturable binding of the glycine antagonist [3H]MDL105,519 with Kd values of 56.9 +/- 6.19 nM (NR1a/NR2A), 26.72 +/- 2.13 nM (NR1a/NR2B), and 21.22 +/- 1.64 nM (NR1a/NR2C), and bound capacities of 17.94 +/- 1.24 pmol/mg membrane protein (NR1a/NR2A), 11.45 +/- 0.67 pmol/mg (NR1a/NR2B), and 16.15 +/- 0.86 (NR1a/NR2C) pmol/mg.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 2C	Rattus norvegicus	268-272
9546654-6	1998	Pharmacological characterization of crude membrane preparations of the recombinant yeast cells showed saturable binding of the glycine antagonist [3H]MDL105,519 with Kd values of 56.9 +/- 6.19 nM (NR1a/NR2A), 26.72 +/- 2.13 nM (NR1a/NR2B), and 21.22 +/- 1.64 nM (NR1a/NR2C), and bound capacities of 17.94 +/- 1.24 pmol/mg membrane protein (NR1a/NR2A), 11.45 +/- 0.67 pmol/mg (NR1a/NR2B), and 16.15 +/- 0.86 (NR1a/NR2C) pmol/mg.	Glycine	127-134	glutamate ionotropic receptor NMDA type subunit 2C	Rattus norvegicus	413-417
9485424-4	1998	In the SH2 domains of SHP-2, the highly conserved alphaA2 Arg is replaced by Gly.	Glycine	77-80	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	22-27
9485424-5	1998	A comparison of the published crystal structures of the Src SH2 domain and the N-terminal SH2 domain of SHP-2 complexed with high-affinity peptides suggested that the alphaA2 Gly of SHP-2 creates a gap which is filled by the side chain of the pY - 2 residue of the bound peptide.	Glycine	175-178	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	104-109
9485424-5	1998	A comparison of the published crystal structures of the Src SH2 domain and the N-terminal SH2 domain of SHP-2 complexed with high-affinity peptides suggested that the alphaA2 Gly of SHP-2 creates a gap which is filled by the side chain of the pY - 2 residue of the bound peptide.	Glycine	175-178	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	182-187
9525449-8	1998	However, in five of seven patients with the homozygous Gly-16 polymorphism, beta2-adrenoceptor density was downregulated by twice daily formoterol, whereas only two such cases exhibited a reduction in maximal FEV1 response to albuterol.	Glycine	55-58	adrenoceptor beta 2	Homo sapiens	76-94
9519875-6	1998	Furthermore, DNA sequencing analysis of the h-neu transcript revealed one of the glioma cell lines, U251MG, had a single nucleotide substitution which resulted in an amino acid change from glycine (GGC) to serine (AGC) at codon 253.	Glycine	189-196	gamma-glutamylcyclotransferase	Homo sapiens	198-201
9490030-9	1998	Replacement of this glycine residue by phenylalanine, which is the residue present at the homologous position in the human beta2-AR, left the beta3-AR pharmacological profile unaltered in terms of specificity and selectivity.	Glycine	20-27	adrenoceptor beta 2	Homo sapiens	123-131
9425086-15	1998	In addition, 14-3-3 zeta bound with lower affinity to a peptide based on the central region of the GP Ibalpha cytoplasmic domain (Arg-557-Gly-575), whereas peptide sequences within the cytoplasmic domains of GP Ibbeta (Arg-160-Arg-175) and GP V (Lys-529-Gly-544) bound 14-3-3 zeta with comparable affinity to the GHSL-containing peptide.	Glycine	254-257	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	Homo sapiens	13-24
9469933-4	1998	Other highly conserved chicken and human CLIP-170/Restin regions confirm the importance of certain protein domains as crucial for protein function, including two CAP-Gly microtubule-binding motifs in the N-terminal globular head domain and two CCHC metal-binding motifs in the C-terminal globular tail domain.	Glycine	166-169	CAP-Gly domain containing linker protein 1	Homo sapiens	41-49
9462844-0	1998	Glycine-enhanced inhibition of rat liver nucleotide pyrophosphatase/phosphodiesterase-I by EDTA: a full account of the reported inhibition by commercial preparations of acidic fibroblast growth factor (FGF-1).	Glycine	0-7	fibroblast growth factor 1	Rattus norvegicus	169-200
9462844-0	1998	Glycine-enhanced inhibition of rat liver nucleotide pyrophosphatase/phosphodiesterase-I by EDTA: a full account of the reported inhibition by commercial preparations of acidic fibroblast growth factor (FGF-1).	Glycine	0-7	fibroblast growth factor 1	Rattus norvegicus	202-207
9462844-3	1998	NPP/PDE inhibition by EDTA (and by unfractionated FGF-1 or the EDTA-containing fractions) was time-dependent, blocked by the substrate p-nitrophenyl-dTMP, and strongly enhanced by glycine.	Glycine	180-187	fibroblast growth factor 1	Rattus norvegicus	50-55
9462844-4	1998	The use of glycine buffers in earlier work was critical to the apparent inhibition by FGF-1.	Glycine	11-18	fibroblast growth factor 1	Rattus norvegicus	86-91
9809654-0	1998	Identification of glycine-extended CCK peptides in endocrine cells and modulation of CCK amide and CCK Gly content and secretion from endocrine tumor cells by an inhibitor of amidation.	Glycine	18-25	cholecystokinin	Mus musculus	35-38
9809654-1	1998	Immunoreactive glycine-extended CCK peptides are found in normal mouse cerebral cortex and are very abundant in some CCK expressing endocrine tumor cells in culture.	Glycine	15-22	cholecystokinin	Mus musculus	32-35
9809654-1	1998	Immunoreactive glycine-extended CCK peptides are found in normal mouse cerebral cortex and are very abundant in some CCK expressing endocrine tumor cells in culture.	Glycine	15-22	cholecystokinin	Mus musculus	117-120
9809654-3	1998	Mouse cerebral cortex, mouse AtT20 and rat WE cells produce mainly CCK 8 amide and CCK 8 Gly.	Glycine	89-92	cholecystokinin	Mus musculus	83-86
9809654-5	1998	The CCK 8 Gly-like peptide from AtT20 cells, after desulfation, co-eluted on HPLC with unsulfated CCK 8 Gly.	Glycine	10-13	cholecystokinin	Mus musculus	4-7
9809654-5	1998	The CCK 8 Gly-like peptide from AtT20 cells, after desulfation, co-eluted on HPLC with unsulfated CCK 8 Gly.	Glycine	10-13	cholecystokinin	Mus musculus	98-101
9809654-7	1998	Treatment with the amidation inhibitor diethyldithiocarbamate greatly decreased cellular content and secretion of CCK amide while it increased cellular content and secretion of CCK Gly.	Glycine	181-184	cholecystokinin	Mus musculus	177-180
9809654-8	1998	These results provide further evidence that glycine-extended CCK peptides are the immediate precursors of amidated CCK peptides.	Glycine	44-51	cholecystokinin	Mus musculus	61-64
9405644-1	1997	The Dld gene product, known as dihydrolipoamide dehydrogenase or the E3 component, catalyzes the oxidation of dihydrolipoyl moieties of four mitochondrial multienzyme complexes: pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, branched-chain alpha-ketoacid dehydrogenase, and the glycine cleavage system.	Glycine	290-297	dihydrolipoamide dehydrogenase	Mus musculus	4-7
9405644-1	1997	The Dld gene product, known as dihydrolipoamide dehydrogenase or the E3 component, catalyzes the oxidation of dihydrolipoyl moieties of four mitochondrial multienzyme complexes: pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, branched-chain alpha-ketoacid dehydrogenase, and the glycine cleavage system.	Glycine	290-297	dihydrolipoamide dehydrogenase	Mus musculus	31-61
9405644-1	1997	The Dld gene product, known as dihydrolipoamide dehydrogenase or the E3 component, catalyzes the oxidation of dihydrolipoyl moieties of four mitochondrial multienzyme complexes: pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, branched-chain alpha-ketoacid dehydrogenase, and the glycine cleavage system.	Glycine	290-297	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	Mus musculus	202-235
9435899-5	1997	Compound 6 (Hpa(SO3H)-Nle-Gly-Trp-Nle-MeAsp-Phe-NH2), derived from moving the N-methyl group from Phe to Asp, decreased CCK-B affinity substantially without affecting CCK-A affinity, giving a compound with 6600-fold selectivity for CCK-A receptors.	Glycine	26-29	cholecystokinin	Rattus norvegicus	167-170
9399746-5	1997	In two ulcerative colitis patients, a mutation was found in the Ki-ras gene (Gly --&gt; Asp 12 and Gly --&gt; Val 12), and in one patient, a mutation in exon 5 of the p53 gene.	Glycine	77-80	KRAS proto-oncogene, GTPase	Homo sapiens	64-70
9399746-5	1997	In two ulcerative colitis patients, a mutation was found in the Ki-ras gene (Gly --&gt; Asp 12 and Gly --&gt; Val 12), and in one patient, a mutation in exon 5 of the p53 gene.	Glycine	99-102	KRAS proto-oncogene, GTPase	Homo sapiens	64-70
9371590-9	1997	By microsequence analysis of the nsp5 and nsp7 N termini, we have now formally confirmed the specificity of the SP for Glu / (Gly/Ser) substrates.	Glycine	126-129	sperm antigen with calponin homology and coiled-coil domains 1	Homo sapiens	33-37
9347800-0	1997	Novel glycine substitution mutations in COL7A1 reveal that the Pasini and Cockayne-Touraine variants of dominant dystrophic epidermolysis bullosa are allelic.	Glycine	6-13	collagen type VII alpha 1 chain	Homo sapiens	40-46
9347800-7	1997	This is the first demonstration of a COL7A1 mutation in DDEB-P, and brings the total number of dominant DEB variants with underlying glycine substitutions in COL7A1 to five, including the pretibial and localized variants as well as the Bart"s syndrome, in addition to DDEB-P and DDEB-CT.	Glycine	133-140	collagen type VII alpha 1 chain	Homo sapiens	158-164
9356388-16	1997	However, the competitive glycine-site antagonist 7-chloro-kynurenic acid blocked the enhancement by BDNF without shifting the dose-inhibition relationship for this antagonist, and Mg2+ consistently depressed the potentiation of NMDA-evoked currents by BDNF, indicating that BDNF does not alter glycine affinity.	Glycine	294-301	brain-derived neurotrophic factor	Rattus norvegicus	100-104
9351806-10	1997	The presence of a type-I" turn in the BG loop, which is dependent on the presence of a glycine residue at position BG3, is indicative of a binding pocket, characteristic of the Src family, SykC and Abl, rather than a binding groove found in PLC-gamma 1C, p85 alpha N and Shc, for example.	Glycine	87-94	SHC adaptor protein 1	Homo sapiens	271-274
9387864-0	1997	The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons.	Glycine	4-11	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	24-29
9387864-2	1997	This localization is similar to that of glycine immunoreactivity, suggesting a causal relationship between GLYT2 expression and glycine distribution.	Glycine	40-47	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	107-112
9387864-2	1997	This localization is similar to that of glycine immunoreactivity, suggesting a causal relationship between GLYT2 expression and glycine distribution.	Glycine	128-135	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	107-112
9387864-8	1997	Moreover, the concentration of glycine into neurons expressing GLYT2 was proportional to the concentration of the transporter.	Glycine	31-38	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	63-68
9387864-10	1997	These evidences indicate that the high content of glycine observed in some neurons in culture is indeed achieved by the concentrative task performed by GLYT2, and that GLYT2 can be used as a reliable marker for identification of glycine-enriched neurons.	Glycine	50-57	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	152-157
9387864-10	1997	These evidences indicate that the high content of glycine observed in some neurons in culture is indeed achieved by the concentrative task performed by GLYT2, and that GLYT2 can be used as a reliable marker for identification of glycine-enriched neurons.	Glycine	50-57	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	168-173
9387864-10	1997	These evidences indicate that the high content of glycine observed in some neurons in culture is indeed achieved by the concentrative task performed by GLYT2, and that GLYT2 can be used as a reliable marker for identification of glycine-enriched neurons.	Glycine	229-236	glycoprotein alpha-galactosyltransferase 1 (inactive)	Homo sapiens	168-173
9336371-5	1997	A variant of the beta2-adrenoceptor gene that encodes glycine rather than arginine at position 16 (Arg16--&gt;Gly) has been shown to confer exaggerated agonist-mediated receptor downregulation, which might attenuate vasodilator response.	Glycine	110-113	adrenoceptor beta 2	Homo sapiens	17-35
9336371-8	1997	We report strong support for association of the prodownregulatory glycine 16 variant of the beta2-adrenoceptor gene with hypertension in African Caribbeans from St Vincent and the Grenadines (chi2=18.9, P=.000014, 1 df).	Glycine	66-73	adrenoceptor beta 2	Homo sapiens	92-110
9307032-8	1997	There is continuous density for the five residues in the P3, P2, P1, P1" and P2" positions of the peptide (Gly-14f to Pro-18f) at the active site of thrombin, and isolated but well-defined density for Tyr-8f at position P9 in the hydrophobic pocket of thrombin.	Glycine	107-110	coagulation factor II, thrombin	Bos taurus	149-157
9307032-8	1997	There is continuous density for the five residues in the P3, P2, P1, P1" and P2" positions of the peptide (Gly-14f to Pro-18f) at the active site of thrombin, and isolated but well-defined density for Tyr-8f at position P9 in the hydrophobic pocket of thrombin.	Glycine	107-110	coagulation factor II, thrombin	Bos taurus	252-260
9815849-1	1997	The androgen receptor (AR) contains glutamine (CAG) and glycine (GGC) repeats that are each polymorphic in length.	Glycine	56-63	gamma-glutamylcyclotransferase	Homo sapiens	65-68
9331262-7	1997	Sequence analysis of the RPGR gene identified a single base pair change, a G--&gt;T transversion, that converts codon 52 GGA (Gly) to TGA (stop codon); the mutation segregates with the disease.	Glycine	126-129	retinitis pigmentosa GTPase regulator	Homo sapiens	25-29
9261173-2	1997	Previous biochemical studies have shown that NTF2 binds directly to the GDP-bound form of Ran/TC4 and to proteins of the nuclear pore complex that contain phenylalanine-glycine repeats.	Glycine	169-176	nuclear transport factor 2	Homo sapiens	45-49
9416989-6	1997	Glycine-extended gastrin was without effect.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
9261872-9	1997	I conclude that the glycine-rich motif is functionally relevant for E. coli dUTPase.	Glycine	20-27	Deoxyuridine triphosphatase	Drosophila melanogaster	76-83
9263920-10	1997	In contrast, cleavage of G34 (the thirty-four amino acid amidated gastrin) at Lys-74-75 to give G17 (the seventeen amino acid amidated gastrin), and of G34-Gly to G17-Gly (G34 and G17 with COOH-terminal glycine), was increased 3-fold after treatment with omeprazole for either 1 or 5 days.	Glycine	156-159	gastrin	Rattus norvegicus	66-73
9263920-10	1997	In contrast, cleavage of G34 (the thirty-four amino acid amidated gastrin) at Lys-74-75 to give G17 (the seventeen amino acid amidated gastrin), and of G34-Gly to G17-Gly (G34 and G17 with COOH-terminal glycine), was increased 3-fold after treatment with omeprazole for either 1 or 5 days.	Glycine	203-210	gastrin	Rattus norvegicus	66-73
9202024-9	1997	In contrast, a mutant fragment in which the single basic residue (Arg99) in the minor loop ("Omega-loop") of the second type I module was converted to a glycine had an essentially normal melting profile but exhibited no binding to heparin and failed to promote matrix-driven translocation.	Glycine	153-160	transmembrane O-mannosyltransferase targeting cadherins 1	Homo sapiens	66-71
11669966-1	1997	Copper(III) complexes of Gly(2)HisGly and Aib(2)HisGly are characterized, where Gly is glycine, His is L-histidine, and Aib is alpha-aminoisobutyric acid.	Glycine	25-28	ANIB1	Homo sapiens	120-123
11669966-1	1997	Copper(III) complexes of Gly(2)HisGly and Aib(2)HisGly are characterized, where Gly is glycine, His is L-histidine, and Aib is alpha-aminoisobutyric acid.	Glycine	34-37	ANIB1	Homo sapiens	120-123
11669966-1	1997	Copper(III) complexes of Gly(2)HisGly and Aib(2)HisGly are characterized, where Gly is glycine, His is L-histidine, and Aib is alpha-aminoisobutyric acid.	Glycine	87-94	ANIB1	Homo sapiens	42-45
9249049-5	1997	Des-(A1-K6)-SHMT and des-(A1-W14)-SHMT catalyzed both the tetrahydrofolate-dependent and tetrahydrofolate-independent reactions, generating characteristic spectral intermediates with glycine and tetrahydrofolate.	Glycine	183-190	serine hydroxymethyltransferase, cytosolic	Ovis aries	12-16
9249049-5	1997	Des-(A1-K6)-SHMT and des-(A1-W14)-SHMT catalyzed both the tetrahydrofolate-dependent and tetrahydrofolate-independent reactions, generating characteristic spectral intermediates with glycine and tetrahydrofolate.	Glycine	183-190	serine hydroxymethyltransferase, cytosolic	Ovis aries	34-38
9215684-7	1997	All affected individuals also carried missense mutations in exon 73 of COL7A1 which lead to different glycine-to-arginine substitutions in the triple-helical domain of collagen VII.	Glycine	102-109	collagen type VII alpha 1 chain	Homo sapiens	71-77
9166417-8	1997	Glycine substitutions in either EMB-9 or LET-2 cause intracellular accumulation of both chains.	Glycine	0-7	Collagen alpha-1(IV) chain	Caenorhabditis elegans	32-37
9182828-3	1997	The study revealed a G-to-A transition at nucleotide 6724 within exon 85 of COL7A1, converting a glycine to an arginine (G2242R) within the triple-helical domain of the type VII collagen in affected individuals.	Glycine	97-104	collagen type VII alpha 1 chain	Homo sapiens	76-82
9192308-9	1997	The dopamine precursor L-beta-3,4-dihydroxyphenylalanine (L-DOPA) inhibited cleavage of 35S-labelled thirty-four amino acid amidated gastrin, i.e. [35S]G34, and of [35S]G34 with COOH-terminal glycine, i.e. [35S]G34-Gly, at a pair of lysine residues, but did not influence cleavage of progastrin at pairs of arginine residues.	Glycine	192-199	gastrin	Rattus norvegicus	133-140
9192308-9	1997	The dopamine precursor L-beta-3,4-dihydroxyphenylalanine (L-DOPA) inhibited cleavage of 35S-labelled thirty-four amino acid amidated gastrin, i.e. [35S]G34, and of [35S]G34 with COOH-terminal glycine, i.e. [35S]G34-Gly, at a pair of lysine residues, but did not influence cleavage of progastrin at pairs of arginine residues.	Glycine	215-218	gastrin	Rattus norvegicus	133-140
9266477-1	1997	The structure of neuromedin C, a 10-residue bombesin-like neuropeptide with the sequence Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2, has been investigated.	Glycine	89-92	gastrin releasing peptide	Homo sapiens	17-29
9266477-1	1997	The structure of neuromedin C, a 10-residue bombesin-like neuropeptide with the sequence Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2, has been investigated.	Glycine	113-116	gastrin releasing peptide	Homo sapiens	17-29
9099683-11	1997	DGKtheta furthermore contains various domains for protein-protein interaction, such as a proline- and glycine-rich domain with a putative SH3 domain-binding site and a pleckstrin homology domain with an overlapping Ras-associating domain.	Glycine	102-109	diacylglycerol kinase theta	Homo sapiens	0-8
9100018-6	1997	In addition, mutation of Glu to Gly or Asn led to increases in their binding to the thyroid hormone response elements (TREs) as homodimers and as heterodimers with the retinoid X receptor.	Glycine	32-35	retinoid X receptor alpha	Homo sapiens	168-187
9087403-4	1997	The proforms of three of the seven different beta-type subunits, beta1/PRE3, beta2/PUP1 and beta5/PRE2, are cleaved between the threonine at position 1 and the last glycine of the pro-sequence, with release of the active-site residue Thr 1.	Glycine	165-172	proteasome core particle subunit beta 1	Saccharomyces cerevisiae S288C	71-75
9122170-5	1997	Limited proteolysis of GroEL oligomers by proteinase K, which removes selectively the conserved glycine- and methionine-rich C terminus, leaving the chaperonin oligomer intact, prevented chaperonin association with lipid membranes.	Glycine	96-103	heat shock protein family D (Hsp60) member 1	Homo sapiens	23-28
9122265-8	1997	These findings suggest that Gly 230 is critical for normal ion conductance in hClC-1 and that this residue resides within the channel pore.	Glycine	28-31	chloride voltage-gated channel 1	Homo sapiens	78-84
9118951-2	1997	A missense mutation (G37S) of the human ENaC beta subunit that causes loss of ENaC function and PHA-1 replaces a glycine that is conserved in the N-terminus of all members of the ENaC gene family.	Glycine	113-120	sodium channel epithelial 1 subunit beta	Homo sapiens	40-49
9118951-2	1997	A missense mutation (G37S) of the human ENaC beta subunit that causes loss of ENaC function and PHA-1 replaces a glycine that is conserved in the N-terminus of all members of the ENaC gene family.	Glycine	113-120	sodium channel epithelial 1 subunit gamma	Homo sapiens	96-101
9066351-4	1997	This condition, previously labeled oculoleptomeningeal amyloidosis, is linked to a mutation at codon 30 of TTR gene, resulting in the substitution of valine with glycine in this family, TTR amyloid deposits were present in the leptomeninges, especially the leptomeningeal vessels, and in the subependymal regions of the ventricular system where they disrupted the ependymal lining and resulted in amyloid-glial formations protruding into and narrowing the ventricular system.	Glycine	162-169	transthyretin	Homo sapiens	107-110
9089691-4	1997	The glycine site antagonists L-689,560 and 7-Cl-kynurenate were 10 times more potent at NR1A/NR2A than at NR1A/NR2B receptor subtypes.	Glycine	4-11	nodal homolog 1 L homeolog	Xenopus laevis	88-92
9089691-4	1997	The glycine site antagonists L-689,560 and 7-Cl-kynurenate were 10 times more potent at NR1A/NR2A than at NR1A/NR2B receptor subtypes.	Glycine	4-11	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	93-97
9089691-4	1997	The glycine site antagonists L-689,560 and 7-Cl-kynurenate were 10 times more potent at NR1A/NR2A than at NR1A/NR2B receptor subtypes.	Glycine	4-11	nodal homolog 1 L homeolog	Xenopus laevis	106-110
9049300-4	1997	The predicted amino acid sequence of p66shc overlaps that of p52shc and contains a unique N-terminal region which is also rich in glycines and prolines (CH2).	Glycine	130-138	src homology 2 domain-containing transforming protein C1	Mus musculus	37-43
9078268-1	1997	Glutathione synthetase catalyses the ATP-dependent ligation of gamma-glutamylcystene with glycine to form glutathione.	Glycine	90-97	glutathione synthetase 2	Arabidopsis thaliana	0-22
9020168-0	1997	Molecular characterization of GCV3, the Saccharomyces cerevisiae gene coding for the glycine cleavage system hydrogen carrier protein.	Glycine	85-92	glycine decarboxylase subunit H	Saccharomyces cerevisiae S288C	30-34
9020168-2	1997	The gene designation has therefore been changed to GCV3, reflecting its role in the glycine cleavage system.	Glycine	84-91	glycine decarboxylase subunit H	Saccharomyces cerevisiae S288C	51-55
9020168-4	1997	Targeted gene replacement shows that GCV3 is not required for growth on minimal medium; however, it is essential when glycine serves as the sole nitrogen source.	Glycine	118-125	glycine decarboxylase subunit H	Saccharomyces cerevisiae S288C	37-41
9008239-0	1997	Glycine substitution mutations in the type VII collagen gene (COL7A1) in dystrophic epidermolysis bullosa: implications for genetic counseling.	Glycine	0-7	collagen type VII alpha 1 chain	Homo sapiens	62-68
9008239-3	1997	In this study, we report novel glycine substitution mutations in COL7A1 in two Japanese families with DEB.	Glycine	31-38	collagen type VII alpha 1 chain	Homo sapiens	65-71
8990170-3	1997	RBP1 belongs to the Ser-Arg-rich (SR) protein family of splicing factors, which have in common a N-terminal RNA recognition motif-type RNA binding domain, a Gly-rich region, and a C-terminal SR domain.	Glycine	157-160	RNA-binding protein 1	Drosophila melanogaster	0-4
8990170-6	1997	The SR domain and the Gly residues within the Gly-rich domain of RBP1 were found to be involved in these protein-protein interactions.	Glycine	22-25	RNA-binding protein 1	Drosophila melanogaster	65-69
8990170-6	1997	The SR domain and the Gly residues within the Gly-rich domain of RBP1 were found to be involved in these protein-protein interactions.	Glycine	46-49	RNA-binding protein 1	Drosophila melanogaster	65-69
9392053-8	1997	Codon 12 point mutation of c-Ha-ras (GGC--&gt;GTC; Gly--&gt;Val) was detected in T24 (grade III, epidermoid, superficial) through single-strand conformation polymorphism, and sequencing analysis.	Glycine	51-54	gamma-glutamylcyclotransferase	Homo sapiens	37-40
8810903-2	1996	The crystal structure of GNMT complexed with AdoMet and acetate, a competitive inhibitor of glycine, has been determined at 2.2 A resolution.	Glycine	92-99	methionine adenosyltransferase 1A	Rattus norvegicus	45-51
8810903-12	1996	Simple modeling indicates that the amino group of the substrate glycine can be placed close to the methyl group of AdoMet within 3.0 A and form a hydrogen bond with the carboxyl group of Glu15 of the adjacent subunit.	Glycine	64-71	methionine adenosyltransferase 1A	Rattus norvegicus	115-121
8823380-2	1996	The MS patients had elevated IgG antibody to EBNA-1, as measured by reactivity with a synthetic glycine/alanine peptide, P62, which represents the glycine/alanine repeat in EBNA-1.	Glycine	96-103	nucleoporin 62	Homo sapiens	121-124
8823380-2	1996	The MS patients had elevated IgG antibody to EBNA-1, as measured by reactivity with a synthetic glycine/alanine peptide, P62, which represents the glycine/alanine repeat in EBNA-1.	Glycine	147-154	nucleoporin 62	Homo sapiens	121-124
8769411-11	1996	Furthermore, through the use of the two-hybrid system, it was demonstrated that both the PAS10 gene product (Pas10p) and the human PTS1 receptor can interact with the COOH-terminal region of human catalase, but that this interaction is abolished by substitutions at the penultimate residue (asparagine-to- aspartate) and at the fourth residue from the COOH terminus (lysine-to-glycine) which abolish PTS functionality.	Glycine	377-384	Pex5p	Saccharomyces cerevisiae S288C	89-94
8691458-1	1996	Mercaptoacyl dipeptides, containing a glycine linked to a C-terminal 5-phenylproline, have been synthesized in order to obtain new highly efficient dual inhibitors of the two zinc metallopeptidases, neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE), which are involved in the control of blood pressure and fluid homeostasis.	Glycine	38-45	membrane metallo-endopeptidase	Rattus norvegicus	199-220
8662700-12	1996	Gly-27 and Gly-54 of LE2k are also well conserved among the lipoyl domains of the alpha-ketoacid dehydrogenase complexes and H-protein.	Glycine	0-3	myosin binding protein H	Homo sapiens	125-134
8662700-12	1996	Gly-27 and Gly-54 of LE2k are also well conserved among the lipoyl domains of the alpha-ketoacid dehydrogenase complexes and H-protein.	Glycine	11-14	myosin binding protein H	Homo sapiens	125-134
8647628-1	1996	Glycine-extended gastrin (gastrin-Gly) stimulates proliferation of AR4-2J pancreatic tumor cell line through a specific receptor, different from the gastrin-cholecystokinin B receptor.	Glycine	0-7	gastrin	Rattus norvegicus	17-24
8647628-1	1996	Glycine-extended gastrin (gastrin-Gly) stimulates proliferation of AR4-2J pancreatic tumor cell line through a specific receptor, different from the gastrin-cholecystokinin B receptor.	Glycine	0-7	gastrin	Rattus norvegicus	26-33
8647628-1	1996	Glycine-extended gastrin (gastrin-Gly) stimulates proliferation of AR4-2J pancreatic tumor cell line through a specific receptor, different from the gastrin-cholecystokinin B receptor.	Glycine	0-7	gastrin	Rattus norvegicus	26-33
8647628-7	1996	Gel chromatography revealed that the predominant molecular forms secreted were glycine-extended gastrin-34 and gastrin- 17.	Glycine	79-86	gastrin	Rattus norvegicus	96-103
8647628-8	1996	Furthermore, epidermal growth factor (EGF), a stimulator of gastrin gene transcription, modulates gastrin-Gly secretion by AR4-2J.	Glycine	106-109	gastrin	Rattus norvegicus	60-67
8647628-8	1996	Furthermore, epidermal growth factor (EGF), a stimulator of gastrin gene transcription, modulates gastrin-Gly secretion by AR4-2J.	Glycine	106-109	gastrin	Rattus norvegicus	98-105
8637005-0	1996	Inter-ring communication is disrupted in the GroEL mutant Arg13 --&gt; Gly; Ala126 --&gt; Val with known crystal structure.	Glycine	71-74	heat shock protein family D (Hsp60) member 1	Homo sapiens	45-50
8637005-1	1996	The crystal structures of the chaperonin GroEL Arg13 --&gt; Gly; Ala126 --&gt; Val double mutant, without and in complex with ATP gamma S, have been determined at atomic resolution.	Glycine	60-63	heat shock protein family D (Hsp60) member 1	Homo sapiens	41-46
8637005-2	1996	Here, we show that the double mutation Arg13 --&gt; Gly; Ala126 --&gt; Val disrupts negative co-operativity between GroEL rings, with respect to ATP, but has little effect on the positive co-operativity within each ring.	Glycine	52-55	heat shock protein family D (Hsp60) member 1	Homo sapiens	116-121
9173082-3	1996	The normal (Gly(12)) or the transforming (Val(12)) c-H-ras gene was expressed in NIH3T3 cells using a metallothionein promoter.	Glycine	12-15	Harvey rat sarcoma virus oncogene	Mus musculus	51-58
8656681-3	1996	Only one transformed lymphoma was found to have a missense mutation at codon 12 of N-ras, resulting in an amino acid change of glycine to serine.	Glycine	127-134	NRAS proto-oncogene, GTPase	Homo sapiens	83-88
8608574-7	1996	Direct sequence analysis of the K-ras oncogene revealed the mutation at codon 12 substituting the wild-type glycine (GGT) for aspartic acid (GAT) in all cancerous lesions of patients with PBM.	Glycine	108-115	KRAS proto-oncogene, GTPase	Homo sapiens	32-37
8608574-8	1996	Simultaneous two-point mutations from the wild-type glycine (GGC) to arginine (CGC) at codon 13 associated with the mutation at codon 12 were also found in one case of gallbladder carcinoma and one case of bile duct carcinoma.	Glycine	52-59	gamma-glutamylcyclotransferase	Homo sapiens	61-64
8621077-1	1996	The Arg-encoding triplet (AGG) in the recognition sequence Ile-Glu-Gly-Arg for factor Xa can be used to generate a StuI restriction site (AGGCCT) which greatly facilitates the construction of DNA fragments encoding fusion proteins.	Glycine	67-70	coagulation factor X	Homo sapiens	79-88
21781669-5	1996	In contrast, [(3)H]glycine binding showed a conspicuous reduction in the striatum and hippocampal CA3 sector and thalamus from mature rats.	Glycine	19-26	carbonic anhydrase 3	Rattus norvegicus	98-101
8622706-6	1996	These results suggest that the substitution GGA (Gly) to GTA (Val) at codon 26 of the murine alpha-globin gene may directly affect the mobility of alpha-globin in UT-PAGE and the base substitution may be a C3H strain-specific polymorphism.	Glycine	49-52	hemoglobin alpha, adult chain 1	Mus musculus	93-105
8622706-6	1996	These results suggest that the substitution GGA (Gly) to GTA (Val) at codon 26 of the murine alpha-globin gene may directly affect the mobility of alpha-globin in UT-PAGE and the base substitution may be a C3H strain-specific polymorphism.	Glycine	49-52	hemoglobin alpha, adult chain 1	Mus musculus	147-159
8644729-8	1996	Inspection of the locations of the glycine substitutions along the COL7A1 polypeptide suggests that the consequences of these mutations, in terms of phenotype and pattern of inheritance, are position independent.	Glycine	35-42	collagen type VII alpha 1 chain	Homo sapiens	67-73
8644730-0	1996	Compound heterozygosity for COL7A1 mutations in twins with dystrophic epidermolysis bullosa: a recessive paternal deletion/insertion mutation and a dominant negative maternal glycine substitution result in a severe phenotype.	Glycine	175-182	collagen type VII alpha 1 chain	Homo sapiens	28-34
8644730-5	1996	Analysis of the maternal COL7A1 allele revealed a glycine-to-arginine substitution in exon 91 (G2351R).	Glycine	50-57	collagen type VII alpha 1 chain	Homo sapiens	25-31
8867213-1	1996	The influence of amino acids with contrasting conformational tendencies on the stereochemistry of oligopeptides has been investigated using an octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe, which contains two helix-promoting Aib residues and a central helix-destabilizing Gly-Gly segment.	Glycine	171-174	ANIB1	Homo sapiens	163-166
8867213-1	1996	The influence of amino acids with contrasting conformational tendencies on the stereochemistry of oligopeptides has been investigated using an octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe, which contains two helix-promoting Aib residues and a central helix-destabilizing Gly-Gly segment.	Glycine	175-178	ANIB1	Homo sapiens	183-186
8867213-1	1996	The influence of amino acids with contrasting conformational tendencies on the stereochemistry of oligopeptides has been investigated using an octapeptide Boc-Leu-Aib-Val-Gly-Gly-Leu-Aib-Val-OMe, which contains two helix-promoting Aib residues and a central helix-destabilizing Gly-Gly segment.	Glycine	175-178	ANIB1	Homo sapiens	183-186
8925252-0	1996	Failure to find associations of the CA repeat polymorphism in the first intron and the Gly-63/Glu-63 polymorphism of the neurotrophin-3 gene with schizophrenia.	Glycine	87-90	neurotrophin 3	Homo sapiens	121-135
8617794-1	1996	The significance of conserved cysteines at positions 288, 337, and 369 in the hormone binding domain of the human vitamin D receptor was evaluated by individual site-directed mutagenesis to glycine.	Glycine	190-197	vitamin D receptor	Homo sapiens	114-132
8648190-7	1996	Adhesion to fibronectin and vitronectin was found to be divalent cation- and arginine-glycine-aspartic acid-dependent, and could be blocked by antibodies to beta 1 or alpha 5, and alpha v or alpha v beta 5, respectively.	Glycine	86-93	vitronectin	Homo sapiens	28-39
8636223-1	1996	Integrin alpha v beta 3 is distinct in its capacity to recognize the sequence Arg-Gly-Asp (RGD) in many extra-cellular matrix (ECM) components.	Glycine	82-85	integrin subunit alpha V	Homo sapiens	0-23
8566085-7	1996	The almost constant presence of glycine residues in the CDR3 and predominance of JH4 with a low level of DQ52 DH usage, suggest that preB cell clones are submitted to an initial selective pressure which should be antigen independent.	Glycine	32-39	prolactin regulatory element binding	Homo sapiens	133-137
8713456-8	1996	Although the substrate transported by NTT4 remains unknown, our findings suggest a possible role for this carrier protein in glutamate/glycine neurotransmission.	Glycine	135-142	solute carrier family 6 member 17	Rattus norvegicus	38-42
8747525-2	1996	8-Guanidino-octanoyl-aspartic acid-phenylalanine (SC-49992), a mimetic of the tetrapeptide arginine-glycine-aspartic acid-phelylalanine, inhibits fibrinogen and vitronectin binding to GP IIb/IIIa.	Glycine	100-107	vitronectin	Homo sapiens	161-172
8747525-2	1996	8-Guanidino-octanoyl-aspartic acid-phenylalanine (SC-49992), a mimetic of the tetrapeptide arginine-glycine-aspartic acid-phelylalanine, inhibits fibrinogen and vitronectin binding to GP IIb/IIIa.	Glycine	100-107	integrin subunit alpha 2b	Homo sapiens	184-190
8962832-3	1995	cDNA clones encoding bovine homologues of glycine (GLYT-1), gamma-aminobutyric acid (GAT-1), creatine (CreaT), and orphan (NTT4) transporters were identified using this strategy.	Glycine	42-49	sodium- and chloride-dependent glycine transporter 1	Bos taurus	51-57
8562428-3	1995	In the course of differentiation BLC 6-derived neurons differentially express voltage-dependent (K+, Na+, Ca2+) and receptor-operated (GABAA, glycine, AMPA, NMDA receptors) ionic channels.	Glycine	142-149	C-X-C motif chemokine ligand 13	Homo sapiens	33-36
7588705-0	1995	Two regions with differential growth-modulating activity in the N-terminal domain of ras GTPase-activating protein (p120GAP) src homology and Gly-Ala-Pro-rich regions.	Glycine	142-145	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	125-128
7491109-3	1995	Herein we report a study of hVDR in which the functional role of five conserved residues was tested by replacing Phe-244, Lys-246, Leu-254, Gln-259, and Leu-262 with glycines by site-directed mutagenesis.	Glycine	166-174	vitamin D receptor	Homo sapiens	28-32
8590017-2	1995	The substitution Gly--&gt;Asp at residue 33 of the cholera toxin B subunit (CTB) has been reported to abolish receptor-binding ability.	Glycine	17-20	phosphate cytidylyltransferase 1B, choline	Homo sapiens	51-74
8590017-2	1995	The substitution Gly--&gt;Asp at residue 33 of the cholera toxin B subunit (CTB) has been reported to abolish receptor-binding ability.	Glycine	17-20	phosphate cytidylyltransferase 1B, choline	Homo sapiens	76-79
7757974-9	1995	The polymorphism was a nucleotide substitution of guanine for thymine (GTC--&gt;GGC) at codon 109, resulting in an amino acid substitution of glycine for valine (Val--&gt;Gly).	Glycine	142-149	gamma-glutamylcyclotransferase	Homo sapiens	80-83
7757974-9	1995	The polymorphism was a nucleotide substitution of guanine for thymine (GTC--&gt;GGC) at codon 109, resulting in an amino acid substitution of glycine for valine (Val--&gt;Gly).	Glycine	171-174	gamma-glutamylcyclotransferase	Homo sapiens	80-83
7727782-8	1995	We found only one mutation of the N-ras gene that was a 2-bp substitution of GGT(Gly) to GTC(Val) at codon 13 among 22 t(1;19)-ALL cases and five cell lines.	Glycine	81-84	NRAS proto-oncogene, GTPase	Homo sapiens	34-39
7889175-0	1995	Missense mutation in CYP11B1 (CGA[Arg-384]--&gt;GGA[Gly]) causes steroid 11 beta-hydroxylase deficiency.	Glycine	52-55	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	21-28
7889175-4	1995	We detected an additional previously uncharacterized mutation: R384G mutation, a single C--&gt;G base substitution in the codon 384 of the exon 7 changing an arginine (CGA) to a glycine (GGA) by sequencing the CYP11B1 gene of Japanese siblings with 11 beta-OHD.	Glycine	178-185	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	210-217
7795148-0	1995	Hybrid peptide containing RGDF (Arg-Gly-Asp-Phe) coupled with the carboxy terminal part of alpha 2-antiplasmin capable of inhibiting platelet aggregation and promoting fibrinolysis.	Glycine	36-39	serpin family F member 2	Homo sapiens	91-110
7776964-3	1995	In the case of the beta 2-adrenergic receptor, it was also reported that mutation of the palmitoylated cysteine to glycine greatly diminished the ability of this receptor to interact with and activate Gs.	Glycine	115-122	adrenoceptor beta 2	Homo sapiens	19-45
8930016-5	1995	That of hIGFBP-4 is predicted as an array of beta-strands that include the glycine and cysteine rich IGFBP consensus pattern and that terminate with a helix.	Glycine	75-82	insulin like growth factor binding protein 4	Homo sapiens	8-16
7650416-7	1995	For example, anticentromere antibodies are strongly associated with HLA-DQB1*0501 (DQ5), DQB1*0301 (DQ7) and other DQB1 alleles possessing a glycine or tyrosine residue in position 26 of the outermost domain.	Glycine	141-148	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	68-76
7650416-7	1995	For example, anticentromere antibodies are strongly associated with HLA-DQB1*0501 (DQ5), DQB1*0301 (DQ7) and other DQB1 alleles possessing a glycine or tyrosine residue in position 26 of the outermost domain.	Glycine	141-148	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	72-76
7650416-7	1995	For example, anticentromere antibodies are strongly associated with HLA-DQB1*0501 (DQ5), DQB1*0301 (DQ7) and other DQB1 alleles possessing a glycine or tyrosine residue in position 26 of the outermost domain.	Glycine	141-148	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	89-93
7894491-3	1994	In addition, we found two missense mutations, one of which changes the final cysteine of the BRCA1 zinc finger motif to glycine.	Glycine	120-127	BRCA1 DNA repair associated	Homo sapiens	93-98
8083230-6	1994	Interestingly, one of the conserved serines of cPLA2, Ser-228, within this domain aligns with the lipase consensus sequence Gly-X(Leu)-Ser(137)-X(Gly)-Gly of PLB.	Glycine	124-127	phospholipase A2 group IVA	Homo sapiens	47-52
8083230-6	1994	Interestingly, one of the conserved serines of cPLA2, Ser-228, within this domain aligns with the lipase consensus sequence Gly-X(Leu)-Ser(137)-X(Gly)-Gly of PLB.	Glycine	146-149	phospholipase A2 group IVA	Homo sapiens	47-52
8083230-6	1994	Interestingly, one of the conserved serines of cPLA2, Ser-228, within this domain aligns with the lipase consensus sequence Gly-X(Leu)-Ser(137)-X(Gly)-Gly of PLB.	Glycine	146-149	phospholipase A2 group IVA	Homo sapiens	47-52
8060313-0	1994	A cell-binding Arg-Gly-Asp sequence is present in close proximity to the major linear antigenic region of HCV NS3.	Glycine	19-22	KRAS proto-oncogene, GTPase	Homo sapiens	110-113
8058050-2	1994	At NR1A/NR2B receptors, in the presence of a saturating concentration of glycine, the magnitude of spermine stimulation was dependent on the concentration of NMDA or glutamate.	Glycine	73-80	nodal homolog 1 L homeolog	Xenopus laevis	3-7
7526265-3	1994	Parvalbumin-immunoreactivity was restricted to those GABA-immunoreactive neurons that also showed glycine-immunoreactivity and was not co-localized with neuropeptide Y-immunoreactivity or NADPH diaphorase activity.	Glycine	98-105	parvalbumin	Rattus norvegicus	0-11
7524891-0	1994	Bioactive Arg-Gly-Asp conformations in anti-integrin GPIIb-IIIa antibodies.	Glycine	14-17	integrin subunit alpha 2b	Homo sapiens	53-58
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	nodal homolog 1 L homeolog	Xenopus laevis	66-70
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	nodal homolog 1 L homeolog	Xenopus laevis	66-69
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	nodal homolog 1 L homeolog	Xenopus laevis	146-150
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	nodal homolog 1 L homeolog	Xenopus laevis	146-150
8190097-4	1994	Glycine-independent stimulation by spermine occurred at homomeric NR1A receptors, which lack the amino-terminal insert in NR1, and at heteromeric NR1A/NR2B receptors but not at heteromeric NR1A/NR2A or NR1A/NR2C receptors.	Glycine	0-7	nodal homolog 1 L homeolog	Xenopus laevis	146-150
8190097-6	1994	Thus, glycine-independent stimulation by polyamines requires the presence of an NR1 variant, such as NR1A, that lacks the amino-terminal insert, but the manifestation of the stimulatory effect is controlled by the type of NR2 subunit present in a heteromeric complex.	Glycine	6-13	nodal homolog 1 L homeolog	Xenopus laevis	80-83
8190097-6	1994	Thus, glycine-independent stimulation by polyamines requires the presence of an NR1 variant, such as NR1A, that lacks the amino-terminal insert, but the manifestation of the stimulatory effect is controlled by the type of NR2 subunit present in a heteromeric complex.	Glycine	6-13	nodal homolog 1 L homeolog	Xenopus laevis	101-105
8170945-6	1994	Sequence analysis revealed a G-->A transition at nucleotide 6118 in the triple helical domain of COL7A1, which converted a glycine residue to a serine (GGT-->AGT).	Glycine	123-130	collagen type VII alpha 1 chain	Homo sapiens	97-103
8157630-2	1994	Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) is an essential, monomeric enzyme that catalyzes the transfer of myristate from CoA to the amino-terminal Gly residue of cellular proteins.	Glycine	184-187	glycylpeptide N-tetradecanoyltransferase NMT1	Saccharomyces cerevisiae S288C	71-76
8132653-5	1994	Mutagenesis of the double-disrupted, shm1 shm2 yeast yielded strains of a single complementation group that are auxotrophic for glycine.	Glycine	128-135	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	42-46
8132653-6	1994	Complementation of the glycine auxotrophy using a yeast genomic library retrieved the SHM1 and SHM2 genes and a third gene designated GLY1.	Glycine	23-30	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	95-99
8132653-7	1994	Gene disruption studies demonstrated that inactivation of SHM1, SHM2, and GLY1 is required to yield yeast that are completely auxotrophic for glycine.	Glycine	142-149	glycine hydroxymethyltransferase SHM2	Saccharomyces cerevisiae S288C	64-68
8125181-3	1994	We demonstrate the developmental expression and thyroid hormone induction of magainin and PGLa (peptide with aminoterminal glycine and carboxyterminal leucinamide), the two most abundant members of the magainin peptide family.	Glycine	123-130	prepro-PGLa S homeolog	Xenopus laevis	90-94
8107101-11	1994	The two CK-2 phosphorylation sites are conserved in all known Vpu sequences and represent the consensus Ser52GlyAsn(Glu/Asp)Ser(Glu/Asp)Gly(Glu/Asp)59.	Glycine	109-112	Vpu	Human immunodeficiency virus 1	62-65
7931256-3	1994	An anticonvulsant prodrug, Milacemide [2-(N-pentyl)glycinamide] is deaminated by MAO-B and this facilitates a mechanism of delivering glycine into the CNS.	Glycine	134-141	monoamine oxidase B	Homo sapiens	81-86
7931256-4	1994	We have found that 2-propyl-pentylamine (2-propyl-1-aminopentane) and N-(2-propylpentyl)glycinamide are also converted by MAO-B to valproic acid and glycine both in vitro and in vivo; these compounds, however, cause severe tremor.	Glycine	149-156	monoamine oxidase B	Homo sapiens	122-127
8152339-7	1994	Similarly, when platelet GpIIb/IIIa receptors were blocked in normal platelets by the tripeptide Arg-Gly-Asp (RGD) or the tetrapeptide Arg-Gly-Asp-Ser (RGDS) at 10(-3) M, agonist-induced platelet aggregation and fibrinogen binding were blocked, but platelet PAI-1 release was not blocked.	Glycine	101-104	integrin subunit alpha 2b	Homo sapiens	25-30
7700853-0	1994	Expression of the FOS proto-oncogene protein in brain after ICV administration of Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2).	Glycine	107-110	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	18-21
7509487-1	1994	We previously reported that a peptide with the sequence Gly-Ala-Pro-Leu (GAPL) found as residues 309-312 in glycoprotein IIb alpha (GPIIb) comprises at least part of a Fg binding site on GPIIb (1).	Glycine	56-59	integrin subunit alpha 2b	Homo sapiens	132-137
7509487-1	1994	We previously reported that a peptide with the sequence Gly-Ala-Pro-Leu (GAPL) found as residues 309-312 in glycoprotein IIb alpha (GPIIb) comprises at least part of a Fg binding site on GPIIb (1).	Glycine	56-59	integrin subunit alpha 2b	Homo sapiens	187-192
7905294-1	1993	Maximal L-glutamate/glycine-evoked currents were inhibited by ethanol in Xenopus laevis oocytes expressing recombinant heteromeric NMDA receptors consisting of NR1-NR2A, NR1-NR2B, and NR1-NR2C subunit combinations.	Glycine	20-27	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	164-168
8300901-5	1993	At this level some glutamic acid decarboxylase (GAD)-containing boutons face glycine receptor-93 kD-associated protein, an observation suggesting that the associated glycine functions as a neurotransmitter.	Glycine	77-84	glutamate decarboxylase 1	Homo sapiens	19-46
8300901-5	1993	At this level some glutamic acid decarboxylase (GAD)-containing boutons face glycine receptor-93 kD-associated protein, an observation suggesting that the associated glycine functions as a neurotransmitter.	Glycine	77-84	glutamate decarboxylase 1	Homo sapiens	48-51
8226878-5	1993	Most significantly a highly repetitive region (19 repeat units of 20 residues each), not found in either human or rat, enlarges one of the characteristic serine-glycine containing regions (designated CS-2) while the other serine-glycine containing domain (designated CS-1) is approximately one-fourth the length of the mammalian CS-1.	Glycine	161-168	calsyntenin 2	Rattus norvegicus	200-204
8226790-8	1993	Xenopus oocytes injected with GLYT2 cRNA transport glycine with a Km of 17 microM, and the uptake of glycine is resistant to inhibition by sarcosine.	Glycine	51-58	solute carrier family 6 member 5 S homeolog	Xenopus laevis	30-35
8226790-8	1993	Xenopus oocytes injected with GLYT2 cRNA transport glycine with a Km of 17 microM, and the uptake of glycine is resistant to inhibition by sarcosine.	Glycine	101-108	solute carrier family 6 member 5 S homeolog	Xenopus laevis	30-35
8405806-4	1993	Elastin is found throughout the vertebrate kingdom and possesses an unusual chemical composition rich in glycine, proline, and hydrophobic amino acids, consonant with its characteristic physical properties.	Glycine	105-112	elastin	Homo sapiens	0-7
7901753-11	1993	However, the inhibitory effect of 1 microM ifenprodil at NR1A/NR2B receptors was reduced by increasing the concentration of glycine.	Glycine	124-131	nodal homolog 1 L homeolog	Xenopus laevis	57-61
7690587-2	1993	Single amino acid variants of bovine pancreatic trypsin inhibitor (BPTI) have been made with glycine or alanine replacement of residues Tyr 35, Gly 37, Asn 43, and Asn 44.	Glycine	93-100	spleen trypsin inhibitor I	Bos taurus	30-65
7690587-2	1993	Single amino acid variants of bovine pancreatic trypsin inhibitor (BPTI) have been made with glycine or alanine replacement of residues Tyr 35, Gly 37, Asn 43, and Asn 44.	Glycine	93-100	spleen trypsin inhibitor I	Bos taurus	67-71
7690587-2	1993	Single amino acid variants of bovine pancreatic trypsin inhibitor (BPTI) have been made with glycine or alanine replacement of residues Tyr 35, Gly 37, Asn 43, and Asn 44.	Glycine	144-147	spleen trypsin inhibitor I	Bos taurus	30-65
8395679-8	1993	Analysis of nucleotide sequence disclosed a multifarious mutation pattern of K-ras codon 12, where the most common conversion was from glycine (GGT) to valine (GTT).	Glycine	135-142	KRAS proto-oncogene, GTPase	Homo sapiens	77-82
7764021-2	1993	The DNA sequence analysis of the cloned mutant skt5 gene showed a nucleotide substitution (causing a glycine-to-glutamic acid substitution) and also a nucleotide insertion (causing a frameshift at the extreme carboxyterminal region) in the structural region from its wild-type gene.	Glycine	101-108	Skt5p	Saccharomyces cerevisiae S288C	47-51
8343162-2	1993	Sequencing analysis revealed an A to G transition at codon 778 leading to replacement of the Asp residue, which is adjacent to the interaction sites of myosin heavy chain (MHC) with actin and is a conserved amino acid residue in various MHC across species, to the Gly residue.	Glycine	264-267	major histocompatibility complex, class I, C	Homo sapiens	152-170
8343162-2	1993	Sequencing analysis revealed an A to G transition at codon 778 leading to replacement of the Asp residue, which is adjacent to the interaction sites of myosin heavy chain (MHC) with actin and is a conserved amino acid residue in various MHC across species, to the Gly residue.	Glycine	264-267	major histocompatibility complex, class I, C	Homo sapiens	172-175
8491783-6	1993	The synthetic peptide, Gly-Arg-Gly-Asp-Ser-Pro, that contains the Arg-Gly-Asp (RGD) integrin recognition site, reversibly inhibited entactin-mediated blastocyst outgrowth in a dose-dependent manner, but had no effect on laminin-mediated outgrowth.	Glycine	23-26	nidogen 1	Mus musculus	132-140
8491783-6	1993	The synthetic peptide, Gly-Arg-Gly-Asp-Ser-Pro, that contains the Arg-Gly-Asp (RGD) integrin recognition site, reversibly inhibited entactin-mediated blastocyst outgrowth in a dose-dependent manner, but had no effect on laminin-mediated outgrowth.	Glycine	31-34	nidogen 1	Mus musculus	132-140
8386269-6	1993	Prevention of phosphorylation at S-313, by altering it to a glycine, prevented detectable phosphorylation of both LMP-1 and p25, indicating that it is a major site on both forms of the molecule.	Glycine	60-67	PDZ and LIM domain 7	Homo sapiens	114-119
8386269-6	1993	Prevention of phosphorylation at S-313, by altering it to a glycine, prevented detectable phosphorylation of both LMP-1 and p25, indicating that it is a major site on both forms of the molecule.	Glycine	60-67	tubulin polymerization promoting protein	Homo sapiens	124-127
8384219-9	1993	Mutation of this serine to a glycine drastically reduces phosphorylation of hVDR by CK-II, in vitro.	Glycine	29-36	vitamin D receptor	Homo sapiens	76-80
8383676-5	1993	Analysis of the hydroxylamine-dependent cleavage of ubiquitin-Cdc34 conjugates at the single Asn-Gly sequence in Cdc34 placed the major ubiquitin linkage site within the C-terminal 215-295 residues of Cdc34.	Glycine	97-100	SCF E2 ubiquitin-protein ligase catalytic subunit CDC34	Saccharomyces cerevisiae S288C	62-67
8383676-5	1993	Analysis of the hydroxylamine-dependent cleavage of ubiquitin-Cdc34 conjugates at the single Asn-Gly sequence in Cdc34 placed the major ubiquitin linkage site within the C-terminal 215-295 residues of Cdc34.	Glycine	97-100	SCF E2 ubiquitin-protein ligase catalytic subunit CDC34	Saccharomyces cerevisiae S288C	113-118
8383676-5	1993	Analysis of the hydroxylamine-dependent cleavage of ubiquitin-Cdc34 conjugates at the single Asn-Gly sequence in Cdc34 placed the major ubiquitin linkage site within the C-terminal 215-295 residues of Cdc34.	Glycine	97-100	SCF E2 ubiquitin-protein ligase catalytic subunit CDC34	Saccharomyces cerevisiae S288C	113-118
7680229-3	1993	The amino acid sequence of the fragment corresponded to residues Gly-115-Glu-121 of VN.	Glycine	65-68	vitronectin	Homo sapiens	84-86
7680433-8	1993	The deduced amino-acid sequence of this VDJ rearrangement, Leu-Arg-Gly, has also been described in rat T cells cloned from experimental allergic encephalomyelitis lesions, which are specific for MBP peptide 87-99 (ref.	Glycine	67-70	myelin basic protein	Rattus norvegicus	195-198
8472268-8	1993	Elastin from dissected aortas had a higher content of aspartate, threonine, serine, glutamate, and lysine and a lower content of glycine, alanine, and valine than elastin from controls (p &lt; 0.05).	Glycine	129-136	elastin	Homo sapiens	0-7
8463133-4	1993	The mutation consisted of a guanine-to-adenine transition in the first base of codon 13 of c-Ki-ras which replaced wild-type glycine with serine, indicating that a putative glycine-to-aspartic acid change is not necessarily the critical event for c-Ki-ras gene activation in codon 13.	Glycine	125-132	KRAS proto-oncogene, GTPase	Homo sapiens	91-99
8448367-2	1993	AtGRP7 and AtGRP8 encode proteins with a bipartite structure consisting of an amino-terminal putative RNA-binding domain and a carboxyl-terminal domain composed of stretches of glycines and serines with interspersed hydrophilic residues.	Glycine	177-185	cold, circadian rhythm, and rna binding 2	Arabidopsis thaliana	0-6
8448367-2	1993	AtGRP7 and AtGRP8 encode proteins with a bipartite structure consisting of an amino-terminal putative RNA-binding domain and a carboxyl-terminal domain composed of stretches of glycines and serines with interspersed hydrophilic residues.	Glycine	177-185	cold, circadian rhythm, and RNA binding 1	Arabidopsis thaliana	11-17
1458688-2	1992	This substitution causes a replacement of glycine (codon GGC) with aspartic acid (codon GAC).	Glycine	42-49	gamma-glutamylcyclotransferase	Homo sapiens	57-60
1477092-3	1992	An amino acid substitution in the exon 1 at codon 54 in the MBP gene (GGC [glycine] to GAC [aspartic acid]) has been shown to be closely associated with low MBP concentration in Caucasoids.	Glycine	75-82	gamma-glutamylcyclotransferase	Homo sapiens	70-73
1469627-6	1992	In the presence of adenosine deaminase (ADA, 2 U/kg.min, n = 6), glycine-induced glomerular hyperfiltration and hyperemia were blunted.	Glycine	65-72	adenosine deaminase	Rattus norvegicus	19-38
1283051-4	1992	In EAU, ten peptide residues p1182-1191 of the IRBP amino acid sequence, were revealed to be sufficiently capable of lymphocyte activation for EAU, and it was also shown that amino acid positions 1182W (tryptophane), 1185G (glycine), 1186V (valine) and 1188P (proline) of IRBP play important roles as the epitopes or agretopes in developing EAU.	Glycine	224-231	retinol binding protein 3, interstitial	Mus musculus	47-51
1385407-9	1992	Replacement of 1 of these residues, a cysteine, with the consensus glycine, conferred SH2-C binding activity toward tyrosine-phosphorylated p62 and epidermal growth factor receptor.	Glycine	67-74	nucleoporin 62	Homo sapiens	140-143
1401911-1	1992	Integrin-associated protein (IAP) is a 50-kDa intrinsic membrane protein that is involved in signal transduction during neutrophil activation by a variety of Arg-Gly-Asp-containing ligands.	Glycine	162-165	CD47 molecule	Homo sapiens	0-27
1401911-1	1992	Integrin-associated protein (IAP) is a 50-kDa intrinsic membrane protein that is involved in signal transduction during neutrophil activation by a variety of Arg-Gly-Asp-containing ligands.	Glycine	162-165	CD47 molecule	Homo sapiens	29-32
1415805-0	1992	Platelet-activating factor antagonists limit glycine changes and behavioral deficits after brain trauma.	Glycine	45-52	PCNA clamp associated factor	Rattus norvegicus	0-26
1303265-1	1992	We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of glycine to arginine.	Glycine	159-166	glucokinase	Homo sapiens	40-51
1511982-0	1992	A dominant mutation in the COL1A1 gene that substitutes glycine for valine causes recurrent lethal osteogenesis imperfecta.	Glycine	56-63	collagen type I alpha 1 chain	Homo sapiens	27-33
1594443-6	1992	The transactivation domain of the Oct-6 protein is different from other described activation domains in that it is highly glycine and alanine rich.	Glycine	122-129	POU class 3 homeobox 1	Homo sapiens	34-39
1421803-1	1992	Analysis of well resolved x-ray crystal structure data of proteins (Brookhaven protein data bank) has been combined with molecular mechanics methods using MM2, to determine possible bioactive conformations for the sequence Arg-Gly-Asp, which is believed to be involved in interactions of adhesive proteins with the glycoprotein complexes on activated platelets.	Glycine	227-230	PNMA family member 2	Homo sapiens	155-158
1378964-6	1992	(2) In S2, arginine and glycine were better substrates for GAA synthesis than canavanine and glycine.	Glycine	24-31	alpha glucosidase	Rattus norvegicus	59-62
1560011-2	1992	Tryptophan residues in positions 48, 65, 186, 363, 388, and 412 of Glut1 were changed to either a glycine or leucine residue.	Glycine	98-105	solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog	Xenopus laevis	67-72
1567424-4	1992	In addition, the Pro-17-Gly peptide competitively inhibited association between hsp70 and p53, an activity which was determined by immunoprecipitation with anti-p53 monoclonal antibody PAb240.	Glycine	24-27	heat shock protein family A (Hsp70) member 4	Homo sapiens	80-85
1348749-5	1992	Cathepsin B/L-like activity was determined with Bz-Val-Lys-Lys-Arg-AFC, elastase-like activity with MeOSuc-Ala-Ala-Pro-Val-AFC, tryptase-like activity with Z-Ala-Ala-Lys-AFC, trypsin-like activity with Z-Gly-Gly-Arg-AFC and dipeptidyl peptidase IV-like activity with Ala-Pro-AFC.	Glycine	204-207	cathepsin B	Homo sapiens	0-11
1515904-8	1992	For comparison, the adult porcine cerebral cortex contained 757 pmol carboxyamidated CCK/g, 20 pmol glycine-extended CCK/g and no proCCK.	Glycine	100-107	cholecystokinin	Rattus norvegicus	117-120
1637142-3	1992	Direct DNA sequencing of the proband"s TTR gene revealed a guanine-for-adenine substitution in the second base of codon 42, producing a glycine for glutamate substitution in the plasma protein.	Glycine	136-143	transthyretin	Homo sapiens	39-42
1552176-3	1992	Immunohistochemical and immunogold methods were used to demonstrate that several peptides previously isolated from the granular glands of the skin, including the antimicrobial peptides magainin and PGLa (a peptide with amino-terminal glycine and carboxy-terminal leucinamide), are also stored in granules present in these enteric cells.	Glycine	234-241	prepro-PGLa S homeolog	Xenopus laevis	198-202
1737002-3	1992	The assignment of calmodulin in the complex was facilitated by the use of selective labeling of the protein with alpha-15N-labeled valine, alanine, lysine, leucine, and glycine.	Glycine	169-176	calmodulin 2	Gallus gallus	18-28
1323869-3	1992	The GP IIb/IIIa complex is an adhesion receptor belonging to the integrin superfamily; it can bind five adhesive proteins containing the arginine-glycine-aspartic acid (RGD) sequence in their structure: fibrinogen (Fg), von Willebrand factor (vWf), thrombospondin (Tsp), fibronectin (Fn) and vitronectin (Vn).	Glycine	146-153	integrin subunit alpha 2b	Homo sapiens	4-10
1350965-4	1992	The levels of aspartate, glutamate, glycine, and taurine were elevated in the CSF during myoclonic jerks and more distinctly immediately after GC.	Glycine	36-43	colony stimulating factor 2	Rattus norvegicus	78-81
1370297-2	1992	The ovarian autoimmune disease is induced in B6AF1 mice by a 15-amino acid peptide (Cys-Ser-Asn-Ser-Ser-Ser-Ser-Gln-Phe-Gln-Ile-His-Gly-Pro-Arg) from mouse ZP3, the sperm-binding component of the zona pellucida that surrounds growing and mature oocytes.	Glycine	132-135	zona pellucida glycoprotein 3	Mus musculus	156-159
1658801-4	1991	This reaction is blocked by the addition of a mutant ubiquitin in which arginine has been substituted for lysine at residue 48, demonstrating that the coupling of ubiquitin to ubiquitin is likely to be through an isopeptide linkage between the C-terminal glycine and Lys48 of ubiquitin.	Glycine	255-262	WUB3	Triticum aestivum	53-62
1658801-4	1991	This reaction is blocked by the addition of a mutant ubiquitin in which arginine has been substituted for lysine at residue 48, demonstrating that the coupling of ubiquitin to ubiquitin is likely to be through an isopeptide linkage between the C-terminal glycine and Lys48 of ubiquitin.	Glycine	255-262	WUB3	Triticum aestivum	163-172
1658801-4	1991	This reaction is blocked by the addition of a mutant ubiquitin in which arginine has been substituted for lysine at residue 48, demonstrating that the coupling of ubiquitin to ubiquitin is likely to be through an isopeptide linkage between the C-terminal glycine and Lys48 of ubiquitin.	Glycine	255-262	WUB3	Triticum aestivum	163-172
1658801-4	1991	This reaction is blocked by the addition of a mutant ubiquitin in which arginine has been substituted for lysine at residue 48, demonstrating that the coupling of ubiquitin to ubiquitin is likely to be through an isopeptide linkage between the C-terminal glycine and Lys48 of ubiquitin.	Glycine	255-262	WUB3	Triticum aestivum	163-172
1799407-2	1991	Induction with nalidixic acid produces high yields of a fusion protein, NS1-FX-beta-globin, where NS1 represents 81 residues of a flu virus protein and FX represents a blood-clotting Factor Xa recognition sequence, Ile-Glu-Gly-Arg.	Glycine	223-226	influenza virus NS1A binding protein	Homo sapiens	72-75
1898363-8	1991	High concentrations of glycine were required for the loading of H-protein with methylamine catalysed by a large excess of P-protein.	Glycine	23-30	myosin binding protein H	Homo sapiens	64-73
1652061-4	1991	In response to CSF-1, cells expressing Phe- or Gly-706 mutant receptors showed increased growth rate and altered cell morphology.	Glycine	47-50	colony stimulating factor 1 (macrophage)	Mus musculus	15-20
1652759-0	1991	Chicken T-cell receptor beta-chain diversity: an evolutionarily conserved D beta-encoded glycine turn within the hypervariable CDR3 domain.	Glycine	89-96	T-cell receptor beta	Gallus gallus	8-28
1869824-8	1991	Using a larger panel of homozygous B cell lines expressing many class II haplotypes, a Ser-309 substituted HA307-319 analogue was shown to bind to most B cell lines expressing Val-86 containing alleles (including DR1 Dw20 and DR4 Dw14) but failed to bind most B cell lines expressing Gly-86 alleles (including DR1 Dw1 and DR4 Dw4).	Glycine	284-287	major histocompatibility complex, class II, DR beta 4	Homo sapiens	226-229
1869824-8	1991	Using a larger panel of homozygous B cell lines expressing many class II haplotypes, a Ser-309 substituted HA307-319 analogue was shown to bind to most B cell lines expressing Val-86 containing alleles (including DR1 Dw20 and DR4 Dw14) but failed to bind most B cell lines expressing Gly-86 alleles (including DR1 Dw1 and DR4 Dw4).	Glycine	284-287	major histocompatibility complex, class II, DR beta 4	Homo sapiens	322-325
1943708-4	1991	Amino acid substitutions that caused decreased binding of mutant CT-B to ganglioside GM1 and abolished toxicity included negatively charged or large hydrophobic residues for Gly-33 and negatively or positively charged residues for Trp-88.	Glycine	174-177	phosphate cytidylyltransferase 1B, choline	Homo sapiens	65-69
2059626-4	1991	The monooxygenase first catalyzes formation of the alpha-hydroxyglycine derivative of the glycine-extended precursor, and the lyase subsequently catalyzes breakdown of the PAM product to the amidated peptide and glyoxylate.	Glycine	64-71	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	172-175
2049091-6	1991	However, azurocidin has Gly for Ser and Ser for His substitutions in the catalytic triad.	Glycine	24-27	azurocidin 1	Homo sapiens	9-19
1903387-10	1991	Ser132 occurs in the consensus sequence Gly-Xaa-Ser-Xaa-Gly present in all serine proteinases and in human pancreatic lipase.	Glycine	40-43	pancreatic lipase	Homo sapiens	107-124
1903387-10	1991	Ser132 occurs in the consensus sequence Gly-Xaa-Ser-Xaa-Gly present in all serine proteinases and in human pancreatic lipase.	Glycine	56-59	pancreatic lipase	Homo sapiens	107-124
1902476-11	1991	The RP-4 had a unique amino-terminal amino sequence and was rich in Gly, Pro, Glx, and Ala residues.	Glycine	68-71	RGD1559532	Rattus norvegicus	4-8
2022640-1	1991	The expression of Ha-ras in quiescent NIH3T3 cells carrying a glucocorticoid-inducible human Ha-ras gene (Val-Gly mutation at codon 12) stimulates total 86Rb+ influx.	Glycine	110-113	Harvey rat sarcoma virus oncogene	Mus musculus	18-24
2022640-1	1991	The expression of Ha-ras in quiescent NIH3T3 cells carrying a glucocorticoid-inducible human Ha-ras gene (Val-Gly mutation at codon 12) stimulates total 86Rb+ influx.	Glycine	110-113	Harvey rat sarcoma virus oncogene	Mus musculus	93-99
1827224-1	1991	Bacteriophage lambda, having a mutation replacing glycine by glutamic acid at the 48th codon of cro, kills the host under N- conditions; we call this the hk mutation.	Glycine	50-57	cro	Escherichia virus Lambda	96-99
1882085-3	1991	In rabbit neuromedin U, the Arg16-Arg17 dibasic residue processing site that is found in pig and dog neuromedin U-25 is replaced by Arg-Gly, but this potential monobasic processing site is not utilized by cleavage enzyme(s) in the intestine.	Glycine	136-139	neuromedin-U-25	Oryctolagus cuniculus	10-22
1999271-2	1991	A peptide corresponding to the COOH-terminal domain of the GLUT1 glucose transporter (Thr-Pro-Glu-Glu-Leu-Phe-His-Pro-Leu-Gly-Ala-Asp-Ser-Gln-Val) was synthesized and conjugated to keyhole limpet hemocyanin through the NH2-terminal of the peptide.	Glycine	122-125	solute carrier family 2 member 1	Homo sapiens	59-64
1846968-4	1991	Human fibrillarin contains an amino-terminal repetitive domain approximately 75-80 amino acids in length that is rich in glycine and arginine residues and is similar to amino-terminal domains in the yeast and Xenopus fibrillarins.	Glycine	121-128	fibrillarin	Homo sapiens	6-17
1793483-5	1991	It leads to the substitution of glycine by aspartic acid in the resulting p21 protein, a consistent amino acid substitution found so far in all types of human cancer exhibiting a codon 13-mutated Ki-ras gene.	Glycine	32-39	KRAS proto-oncogene, GTPase	Homo sapiens	196-202
2006543-0	1991	The scotopic threshold response of the cat ERG is suppressed selectively by GABA and glycine.	Glycine	85-92	ETS transcription factor ERG	Felis catus	43-46
1698787-6	1990	In contrast to PAI-1, ECM-associated VN was resistant toward glycine (pH 2.3), guanidine or urokinase treatment, suggesting that VN was tightly associated with the ECM network.	Glycine	61-68	vitronectin	Homo sapiens	37-39
2222420-5	1990	The growth medium contained in addition alpha-amidated CCK-33, glycine-extended CCK-8 and pro-CCK.	Glycine	63-70	cholecystokinin	Rattus norvegicus	80-83
2222420-5	1990	The growth medium contained in addition alpha-amidated CCK-33, glycine-extended CCK-8 and pro-CCK.	Glycine	63-70	cholecystokinin	Rattus norvegicus	80-83
2386811-9	1990	We propose that in the repeating sequences of elastin an equilibrium exists between a gamma-turn structure and a beta-turn structure in the Pro-Gly segment resulting in a structure that combines flexibility with strong conformational preferences.	Glycine	144-147	elastin	Homo sapiens	46-53
2121673-8	1990	These results indicate that CS1 peptide of fibronectin, lacking the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models.	Glycine	72-75	chorionic somatomammotropin hormone 1	Homo sapiens	28-31
1975516-4	1990	These differences correlate with high sequence divergence in the proline- and glycine-rich region (residues 47-71) that forms the hsc70 binding site.	Glycine	78-85	heat shock protein family A (Hsp70) member 8	Homo sapiens	130-135
2165127-5	1990	Analyses of the gD genes by dideoxy-sequencing techniques identified a base difference in the coding sequences and predicted that the ANG gD gene codes for alanine (GCC codon) at amino acid position 84 in the open reading frame and the ANG path gD gene codes for glycine (GGC codon) at this site.	Glycine	263-270	atypical chemokine receptor 1 (Duffy blood group)	Homo sapiens	16-18
2165127-5	1990	Analyses of the gD genes by dideoxy-sequencing techniques identified a base difference in the coding sequences and predicted that the ANG gD gene codes for alanine (GCC codon) at amino acid position 84 in the open reading frame and the ANG path gD gene codes for glycine (GGC codon) at this site.	Glycine	263-270	atypical chemokine receptor 1 (Duffy blood group)	Homo sapiens	138-140
1975652-9	1990	Seizure severity (Rb1/Rb2) seems to correlate, in some areas, with additional lower amounts of GABA already reported and, to a lower extent, of Asp (-19% in striatum, inferior colliculus and cerebellum), of Tau and Gly; a tendency for a rise in Gln content was observed in certain others (10-20% in olfactory bulb, thalamus, hypothalamus, substantia nigra, and frontal, temporal and occipital cortex).	Glycine	215-218	RB transcriptional corepressor 1	Mus musculus	18-21
1975652-9	1990	Seizure severity (Rb1/Rb2) seems to correlate, in some areas, with additional lower amounts of GABA already reported and, to a lower extent, of Asp (-19% in striatum, inferior colliculus and cerebellum), of Tau and Gly; a tendency for a rise in Gln content was observed in certain others (10-20% in olfactory bulb, thalamus, hypothalamus, substantia nigra, and frontal, temporal and occipital cortex).	Glycine	215-218	RB transcriptional corepressor like 2	Mus musculus	22-25
1975761-1	1990	Two selective modulators of N-methyl-D-aspartate (NMDA) receptor function, dithiothreitol (DTT) and glycine, each dramatically enhanced long-term potentiation (LTP) in area CA1 of the hippocampus slice.	Glycine	100-107	carbonic anhydrase 1	Homo sapiens	173-176
1693626-1	1990	Association of a novel beta 1-related subunit with alpha v. We report the isolation from two human neuroblastoma cell lines of an Arg-Gly-Asp-dependent integrin complex capable of binding to vitronectin, fibronectin, and type I collagen.	Glycine	134-137	vitronectin	Homo sapiens	191-202
1692034-3	1990	Recent cDNA cloning reveals that like other adhesive proteins, Vn contains the sequence Arg-Gly-Asp and binds to some members of the integrin class of adhesive membrane receptors.	Glycine	92-95	vitronectin	Homo sapiens	63-65
2179417-7	1990	The K-ras mutations involve glycine to cysteine and glycine to asparagine amino acid changes.	Glycine	28-35	KRAS proto-oncogene, GTPase	Homo sapiens	4-9
2179417-7	1990	The K-ras mutations involve glycine to cysteine and glycine to asparagine amino acid changes.	Glycine	52-59	KRAS proto-oncogene, GTPase	Homo sapiens	4-9
2179417-9	1990	In one SCC, a point mutation was detected at codon 12 of the K-ras gene, involving a glycine to cysteine substitution in the gene product.	Glycine	85-92	KRAS proto-oncogene, GTPase	Homo sapiens	61-66
2111891-6	1990	To test this hypothesis the synthetic oxytocin precursor intermediates oxytocin-glycine (G), oxytocin-glycine-lysine (GK), and oxytocin-glycine-lysine-arginine (GKR), were tested for cross-reactivity with the various oxytocin antisera used in this laboratory to distinguish the oxytocin-like peptide from oxytocin.	Glycine	80-87	oxytocin/neurophysin I prepropeptide	Homo sapiens	38-46
2320569-3	1990	Each of the protein in this family, which range from 47 to 83 residues, contains an Arg-Gly-Asp amino acid sequence found in protein ligands that binds to GPIIb-IIIa, a high (17 +/- 1%) cysteine content conserved in the primary sequence, and a homologous N-terminal region absent only in the echistatin isoforms.	Glycine	88-91	integrin subunit alpha 2b	Homo sapiens	155-160
2180962-8	1990	The anchorage-independent phenotype of c-sis-overexpressing cells was blocked by the cell adhesion sequence of fibronectin, Arg-Gly-Asp-Ser.	Glycine	128-131	platelet derived growth factor subunit B	Homo sapiens	39-44
2307836-5	1990	We show that CD9-induced aggregation is an active process which proceeds at 37 degrees C, but not at 4 degrees C, requires the expenditure of metabolic energy, and a functioning cytoskeleton, and is not inhibited by Arg-Gly-Asp-Ser peptide.	Glycine	220-223	CD9 molecule	Homo sapiens	13-16
2404977-12	1990	Surprisingly, the catalytic serine of azurocidin is replaced by glycine, explaining its inability to label with [3H]diisopropyl fluorophosphate.	Glycine	64-71	azurocidin 1	Homo sapiens	38-48
2078309-3	1990	The CSF concentrations of glycine, leucine and valine were also significantly reduced in the DAT cases.	Glycine	26-33	solute carrier family 6 member 3	Homo sapiens	93-96
2078309-4	1990	Furthermore, in the DAT cases significant decreases were observed in the ratio between CSF and plasma (CSF/P) levels for alanine, glutamine, glycine, phenylalanine and valine, when compared with controls.	Glycine	141-148	solute carrier family 6 member 3	Homo sapiens	20-23
2153293-0	1990	The allosteric glycine site of the N-methyl-D-aspartate receptor modulates GABAergic-mediated synaptic events in neonatal rat CA3 hippocampal neurons.	Glycine	15-22	carbonic anhydrase 3	Rattus norvegicus	126-129
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	60-63	synaptophysin	Homo sapiens	64-77
2139224-3	1990	The consensus peptide for each is rhodopsin Tyr Pro Pro Gln Gly synaptophysin Tyr Gly Pro Gln Gly synexin Tyr Pro Pro Pro Pro Gly gliadin Tyr Pro Pro Pro Gln Pro RNA polymerase II Tyr Ser Pro Thr Ser Pro Ser hordein Phe Pro Gln Gln Pro Gln Gln Pro gluten Tyr Pro Thr Ser Pro Gln Gln Gly Tyr Although there is obvious variation of sequence and of length, the penta- to nonapeptides share an initial Tyr (or Phe) and have high Pro contents and abundant Gly, Gln, and Ser.	Glycine	82-85	synaptophysin	Homo sapiens	64-77
33782401-4	2021	We find that PRMT7 predominantly methylates a glycine and arginine motif; multiple PRMT7-regulated arginine methylation sites are close to phosphorylations sites; methylation sites and proximal sequences are vulnerable to cancer mutations; and methylation is enriched in proteins associated with spliceosome and RNA-related pathways.	Glycine	46-53	protein arginine methyltransferase 7	Homo sapiens	13-18
15496467-4	2004	Our results with mutation of the conserved Ala to Gly in two S lipoxygenases (mouse 8S-LOX and human 15-LOX-2) and the corresponding Gly-Ala substitution in two R lipoxygenases (human 12R-LOX and coral 8R-LOX) reveal that the basis for R or S stereo-control also involves a switch in the position of oxygenation on the substrate.	Glycine	133-136	arachidonate 12-lipoxygenase, 12R type	Homo sapiens	184-191
34975567-7	2021	Six of the metabolites were returned to the normal levels in different degrees after 8 weeks medication, only Glycine continuously decreased in the acute and significant improvement stages of bipolar depression (VIP > 1 and p < 0.05).	Glycine	110-117	diphosphoinositol pentakisphosphate kinase 1	Homo sapiens	212-219
34846143-1	2021	Two dual stimuli-activated photosensitizers were developed, in which two or three glutathione (GSH)-responsive 2,4-dinitrobenzenesulfonate (DNBS)-substituted zinc(II) phthalocyanine units were connected via one or two cathepsin B-cleavable Gly-Phe-Leu-Gly peptide linker(s).	Glycine	240-243	cathepsin B	Homo sapiens	218-229
34215932-4	2021	SHMT2 is a PLP-dependent tetrameric enzyme that catalyzes the reversible transition from serine to glycine, thus promoting the production of one-carbon units that are indispensable for cell growth and regulation of the redox and epigenetic states of cells.	Glycine	99-106	serine hydroxymethyltransferase 2	Homo sapiens	0-5
34646012-5	2021	Here we show that the cytokine-binding segments of human ALK and LTK comprise a novel architectural chimera of a permuted TNF-like module that braces a glycine-rich subdomain featuring a hexagonal lattice of long polyglycine type II helices.	Glycine	152-159	ALK receptor tyrosine kinase	Homo sapiens	57-60
34901821-0	2021	HIF-1alpha overexpression in mesenchymal stem cell-derived exosome-encapsulated arginine-glycine-aspartate (RGD) hydrogels boost therapeutic efficacy of cardiac repair after myocardial infarction.	Glycine	89-96	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	0-10
34663888-1	2021	The identity of a glycinergic synapse is maintained presynaptically by the activity of a surface glycine transporter, GlyT2, which recaptures glycine back to presynaptic terminals to preserve vesicular glycine content.	Glycine	97-104	solute carrier family 6 member 5	Danio rerio	118-123
34663888-1	2021	The identity of a glycinergic synapse is maintained presynaptically by the activity of a surface glycine transporter, GlyT2, which recaptures glycine back to presynaptic terminals to preserve vesicular glycine content.	Glycine	142-149	solute carrier family 6 member 5	Danio rerio	118-123
34663888-1	2021	The identity of a glycinergic synapse is maintained presynaptically by the activity of a surface glycine transporter, GlyT2, which recaptures glycine back to presynaptic terminals to preserve vesicular glycine content.	Glycine	202-209	solute carrier family 6 member 5	Danio rerio	118-123
34524407-4	2021	Recently, calpain-2 (CAPN2) was reported to cleave JP2 at a novel site between Glycine 482 (G482) and Threonine 483 (T483).	Glycine	79-86	junctophilin 2	Homo sapiens	51-54
34630451-5	2021	N-myristoylation at glycine-2 is essential for plasma membrane association and recruiting SOS2 to activate SOS1, whereas S-acylation at cysteine-3 redirects SOS3 toward the nucleus.	Glycine	20-27	Protein kinase superfamily protein	Arabidopsis thaliana	90-94
34251635-9	2021	ATF4, in response to low concentrations of cellular amino acids, mediates the transcription of groups of genes such as those for amino acid transport and biosynthesis (ASNS, CAT-1, SNAT2), autophagy (ATG3, ATG10, ATG12), and serine-glycine synthesis (PHGDH, PSAT1, PSPH, MTHFD2).	Glycine	232-239	activating transcription factor 4	Homo sapiens	0-4
35597955-11	2022	The variants with the largest posterior inclusion probability in the two credible sets were an amino acid change in HLA-DQB1 (glutamine to histidine at residue 253) and a multi-allelic amino acid change in HLA-DRB1 (presence/absence of serine, glycine or leucine at residue 11).	Glycine	244-251	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	116-124
35545256-3	2022	At pharmacologically active doses of {greater than or equal to}0.1 mg/kg, both mouse Fc-mouse IL-10 and human Fc-human IL-10, constructed as the C-terminus of the Fc domain fused with IL-10 via a glycine-serine polypeptide linker, exhibited nonlinear pharmacokinetics after intravenous administration to mice at the doses of 0.05, 0.5, and 5 mg/kg.	Glycine	196-203	interleukin 10	Homo sapiens	119-124
35136972-10	2022	RNA-Seq and verification showed that glycine regulated the ferroptosis pathway through increase S-adenosylmethionine (SAM) concentration and decrease the expression of GPX4 and FTH1 by promoting SAM-mediated GPX4 promoter methylation and reducing FTH1 expression in RA FLS.	Glycine	37-44	ferritin heavy polypeptide 1	Mus musculus	177-181
35136972-10	2022	RNA-Seq and verification showed that glycine regulated the ferroptosis pathway through increase S-adenosylmethionine (SAM) concentration and decrease the expression of GPX4 and FTH1 by promoting SAM-mediated GPX4 promoter methylation and reducing FTH1 expression in RA FLS.	Glycine	37-44	ferritin heavy polypeptide 1	Mus musculus	247-251
34624079-6	2022	Mechanistically, SHMT2 inhibition led to a significant reduction of intracellular glycine and formate levels, which inhibited the mTOR pathway and thereby triggered autophagic degradation of the oncogenic transcription factor TCF3.	Glycine	82-89	serine hydroxymethyltransferase 2	Homo sapiens	17-22