PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
12193057-7	2002	Pretreatment with N-benzyloxycarbonyl-Ile-Glu(O-t-Bu)-Ala-leucinal or BAY 11-7082, both of which are suppressors of NF-kappa B activation, effectively attenuated basal and TNF-alpha-induced ET-1 mRNA expression.	o-t-bu	46-52	nuclear factor kappa B subunit 1	Homo sapiens	116-126
12492319-2	2002	Reduction reactions were successful and resulted in anti/syn ratios of alcohols of >95:5 (80% yield), using LiAlH(O-t-Bu)(3) in EtOH at -78 degrees C under chelation control, and 5:95 (98% yield), using NB-Enantride in THF at -78 degrees C under Felkin-Anh control.	o-t-bu	117-123	synemin	Homo sapiens	57-60
12193057-7	2002	Pretreatment with N-benzyloxycarbonyl-Ile-Glu(O-t-Bu)-Ala-leucinal or BAY 11-7082, both of which are suppressors of NF-kappa B activation, effectively attenuated basal and TNF-alpha-induced ET-1 mRNA expression.	o-t-bu	46-52	tumor necrosis factor	Homo sapiens	172-181
12193057-7	2002	Pretreatment with N-benzyloxycarbonyl-Ile-Glu(O-t-Bu)-Ala-leucinal or BAY 11-7082, both of which are suppressors of NF-kappa B activation, effectively attenuated basal and TNF-alpha-induced ET-1 mRNA expression.	o-t-bu	46-52	endothelin 1	Homo sapiens	190-194
7488014-8	1995	Z-IE(O-t-Bu)A-Leucinal abolished NOX- production and inducible iNOS expression at 1 microM and showed over 50% inhibition at 10 nM.	o-t-bu	5-11	nitric oxide synthase 2	Rattus norvegicus	63-67
8655651-10	1995	The proteasome inhibitor Cbz-Ile-Glu(O-t-Bu)-Ala-leucinal (PSI), which stabilizes the phospho form of I kappa B-alpha, only slightly increased the amount of conjugates indicating that the conjugation of I kappa B-alpha with ubiquitin was the rate-limiting step in I kappa B-alpha degradation, and not its phosphorylation or proteolysis.	o-t-bu	37-43	NFKB inhibitor alpha	Homo sapiens	102-117
3342870-8	1988	Thus Cbz-Phe-Tyr(O-t-Bu)CHN2 inactivates cathepsin L with a rate 2.5 x 10(4) greater than that for cathepsin B.	o-t-bu	17-23	chimerin 2	Homo sapiens	24-28
7957109-4	1994	Micromolar amounts of the peptide Cbz-Ile-Glu(O-t-Bu)-Ala-leucinal (PSI), a specific inhibitor of the chymotrypsin-like activity of the proteasome, prevented activation of NF-kappa B in response to tumor necrosis factor-alpha (TNF) and okadaic acid (OA) through inhibition of I kappa B-alpha degradation.	o-t-bu	46-52	nuclear factor kappa B subunit 1	Homo sapiens	172-182
7957109-4	1994	Micromolar amounts of the peptide Cbz-Ile-Glu(O-t-Bu)-Ala-leucinal (PSI), a specific inhibitor of the chymotrypsin-like activity of the proteasome, prevented activation of NF-kappa B in response to tumor necrosis factor-alpha (TNF) and okadaic acid (OA) through inhibition of I kappa B-alpha degradation.	o-t-bu	46-52	tumor necrosis factor	Homo sapiens	198-225
7957109-4	1994	Micromolar amounts of the peptide Cbz-Ile-Glu(O-t-Bu)-Ala-leucinal (PSI), a specific inhibitor of the chymotrypsin-like activity of the proteasome, prevented activation of NF-kappa B in response to tumor necrosis factor-alpha (TNF) and okadaic acid (OA) through inhibition of I kappa B-alpha degradation.	o-t-bu	46-52	tumor necrosis factor	Homo sapiens	227-230
7957109-4	1994	Micromolar amounts of the peptide Cbz-Ile-Glu(O-t-Bu)-Ala-leucinal (PSI), a specific inhibitor of the chymotrypsin-like activity of the proteasome, prevented activation of NF-kappa B in response to tumor necrosis factor-alpha (TNF) and okadaic acid (OA) through inhibition of I kappa B-alpha degradation.	o-t-bu	46-52	NFKB inhibitor alpha	Homo sapiens	276-291
3342870-8	1988	Thus Cbz-Phe-Tyr(O-t-Bu)CHN2 inactivates cathepsin L with a rate 2.5 x 10(4) greater than that for cathepsin B.	o-t-bu	17-23	cathepsin L	Homo sapiens	41-52
3342870-8	1988	Thus Cbz-Phe-Tyr(O-t-Bu)CHN2 inactivates cathepsin L with a rate 2.5 x 10(4) greater than that for cathepsin B.	o-t-bu	17-23	cathepsin B	Homo sapiens	99-110