PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 28966239-3 2017 In contrast, the biological activities of eudesmane-type sesquiterpene lactones on the non-canonical NF-kappaB signaling pathway remain unclear. eudesmane 42-51 nuclear factor kappa B subunit 1 Homo sapiens 101-110 22506722-1 2012 We present in this report the development of a convergent and highly stereocontrolled cycloaddition strategy toward the synthesis of C-1, C-6, and C-14 tris-oxygenated eudesmane sesquiterpenoids. eudesmane 168-177 heterogeneous nuclear ribonucleoprotein C Homo sapiens 133-136 22153345-3 2012 Our present study reveals that eudesmane-type alpha-methylene gamma-lactones and alpha-bromo ketones inhibit multiple steps in the NF-kappaB signaling pathway induced by IL-1alpha and TNF-alpha. eudesmane 31-40 interleukin 1 alpha Homo sapiens 170-179 22153345-3 2012 Our present study reveals that eudesmane-type alpha-methylene gamma-lactones and alpha-bromo ketones inhibit multiple steps in the NF-kappaB signaling pathway induced by IL-1alpha and TNF-alpha. eudesmane 31-40 tumor necrosis factor Homo sapiens 184-193