PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 7939052-3 1994 The aminopenicillins (including the beta-lactamase inhibitor combinations) were highly active against the streptococci, in combination with a beta-lactamase inhibitor they covered the majority of the bla+ E. coli and Proteus mirabilis and between 60 to 80% of the Klebsiella spp. aminopenicillins 4-20 beta-lactamase Escherichia coli 200-203 20223934-7 2010 We exploited the nematode to rapidly discern chemical effectors of torsinA and identified two classes of antibiotics, quinolones and aminopenicillins, which enhance WT torsinA activity in two separate in vivo assays. aminopenicillins 133-149 torsin family 1, member A (torsin A) Mus musculus 168-175 15649996-5 2005 Over 93% of M. catarrhalis and nearly 15% of H. influenzae were beta-lactamase positive rendering these sub-populations resistant to aminopenicillins. aminopenicillins 133-149 beta-lactamase TEM-1 Haemophilus influenzae 64-78 17459665-0 2007 Influence of Haemophilus influenzae beta-lactamase production and/or ftsI gene mutations on in vitro activity of and susceptibility rates to aminopenicillins and second- and third-generation cephalosporins. aminopenicillins 141-157 beta-lactamase TEM-1 Haemophilus influenzae 36-50 14977407-5 2004 The structural similarity of a variety of drugs with the basic structure of di- or tripeptides explains the transport of aminocephalosporins and aminopenicillins, selected angiotensin-converting inhibitors, and amino acid-conjugated nucleoside-based antiviral agents by PEPT1. aminopenicillins 145-161 solute carrier family 15 member 1 Homo sapiens 270-275 1516458-2 1992 The most common enzymes responsible for resistance to aminopenicillins and older (1st generation) cephalosporins are the TEM-1, TEM-2, OXA-1 and SHV-1 enzymes, all of which are plasmid-mediated. aminopenicillins 54-70 CD248 molecule Homo sapiens 121-126 8021801-2 1994 1H NMR resonances of the aminopenicillins, together with those for their 5R, 6R and 5S, 6R penicilloic acids and diketopiperazine metabolites were detected, assigned and quantified in urine samples with the aid of spin-echo NMR techniques. aminopenicillins 25-41 spindlin 1 Homo sapiens 214-218 1495829-3 1992 EF4 bacteria were susceptible to aminopenicillins, carboxypenicillins, ureidopenicillins, third-generation cephalosporins, fluoroquinolones, rifampicin, and trimethoprime-sulfamethoxazole. aminopenicillins 33-49 GTP binding elongation factor GUF1 Homo sapiens 0-3 1516458-2 1992 The most common enzymes responsible for resistance to aminopenicillins and older (1st generation) cephalosporins are the TEM-1, TEM-2, OXA-1 and SHV-1 enzymes, all of which are plasmid-mediated. aminopenicillins 54-70 RASD family member 2 Homo sapiens 128-133 1516458-2 1992 The most common enzymes responsible for resistance to aminopenicillins and older (1st generation) cephalosporins are the TEM-1, TEM-2, OXA-1 and SHV-1 enzymes, all of which are plasmid-mediated. aminopenicillins 54-70 OXA1L mitochondrial inner membrane protein Homo sapiens 135-140 1925470-3 1991 However, in combination with aminopenicillins they exhibit marked synergism both in vitro and in vivo against many beta-lactamase producing bacterial strains. aminopenicillins 29-45 beta-lactamase TEM-1 Haemophilus influenzae 115-129