PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2322933-0	1990	Vasoactive intestinal polypeptide (VIP) induces calcium mobilization in the human neuroblastoma cell line SK-N-SH.	sk-n-sh	106-113	vasoactive intestinal peptide	Homo sapiens	0-33
11324578-2	1998	The results were as follows: (1) PKC agonist phorbol-12-myristate, 13-acetate (PMA) stimulated the glutamate uptake in the rat cerebral cortex synaptosomes and cell line of BT-325, but not in the cell line of SK-N-SH.	sk-n-sh	209-216	protein kinase C, gamma	Rattus norvegicus	33-36
8020586-7	1994	SK-N-SH and its derivative tumors expressed heterogeneous amounts of beta 1 and alpha 2 at the cell surface, while only subcutaneous tumor cells expressed alpha V. Parental SK-N-SH cells contained two subpopulations, half of which expresses alpha 3, while the other half does not; all subcutaneous tumor cells retained this two-subpopulation pattern, indicating that primary tumor formation does not lead to clonal dominance of alpha 3- or alpha 3+ cell types in larger primary tumors.	sk-n-sh	0-7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	69-87
2322933-0	1990	Vasoactive intestinal polypeptide (VIP) induces calcium mobilization in the human neuroblastoma cell line SK-N-SH.	sk-n-sh	106-113	vasoactive intestinal peptide	Homo sapiens	35-38
31811458-8	2020	miR-494-3p expression was increased and BDNF level was decreased in MPP+-treated SK-N-SH and CHP 212 cells, which were reversed by introduction of PPX.	sk-n-sh	81-88	brain derived neurotrophic factor	Homo sapiens	40-44
3359262-3	1988	Specific [125I]insulin binding was 24.4% for NG108, 16.9% for SK-N-MC and 5.2% for SK-N-SH at membrane protein concentrations of 0.4 mg/ml.	sk-n-sh	83-90	insulin	Homo sapiens	15-22
3359262-4	1988	IC50 for [125I]insulin binding was 3.4 nM in NG108 membrane preparations and 0.9 nM for SK-N-SH and 1.8 nM in SK-N-MC membranes.	sk-n-sh	88-95	insulin	Homo sapiens	15-22
2961554-1	1988	High affinity insulin-like growth factor I (IGF-I) receptors are expressed by two human neural derived cell lines, SK-N-SH and SK-N-MC.	sk-n-sh	115-122	insulin like growth factor 1	Homo sapiens	14-42
2961554-1	1988	High affinity insulin-like growth factor I (IGF-I) receptors are expressed by two human neural derived cell lines, SK-N-SH and SK-N-MC.	sk-n-sh	115-122	insulin like growth factor 1	Homo sapiens	44-49
2961554-2	1988	Specific [125I]IGF-I binding to crude membranes was 23.4% for SK-N-SH and 10.7% for SK-N-MC, with 50% inhibition of binding by unlabeled IGF-I between 0.6-0.7 nM.	sk-n-sh	62-69	insulin like growth factor 1	Homo sapiens	15-20
2961554-4	1988	The IGF-I receptor alpha-subunits of SK-N-SH have an apparent Mr of 126K, whereas that for SK-N-MC is 132K.	sk-n-sh	37-44	insulin like growth factor 1	Homo sapiens	4-9
2961554-6	1988	Furthermore, IGF-I stimulated iododeoxyuridine uptake in both SK-N-SH and SK-N-MC in a dose-dependent manner, suggesting that these cells may be used to study the role of IGF-I action on neural tissues.	sk-n-sh	62-69	insulin like growth factor 1	Homo sapiens	13-18
2961554-6	1988	Furthermore, IGF-I stimulated iododeoxyuridine uptake in both SK-N-SH and SK-N-MC in a dose-dependent manner, suggesting that these cells may be used to study the role of IGF-I action on neural tissues.	sk-n-sh	62-69	insulin like growth factor 1	Homo sapiens	171-176
6793214-4	1981	The human neuroblastoma in vitro cell lines SK-N-SH, SH-SY5Y, SK-N-MC and IMR-32 contained considerably lower relative levels of NSE compared to the levels in the neuroblastoma biopsies.	sk-n-sh	44-51	enolase 2	Homo sapiens	129-132
28236071-9	2017	In addition, HSP78 on the cell surface was upregulated in human neuroblastoma cells (SK-N-SH) infected with EV71.	sk-n-sh	85-92	caseinolytic mitochondrial matrix peptidase chaperone subunit B	Homo sapiens	13-18
26497035-8	2016	Pretreatment with these inhibitors or transfection with MMP-9 siRNA also blocked thrombin-induced SK-N-SH cell migration.	sk-n-sh	98-105	matrix metallopeptidase 9	Homo sapiens	56-61
26497035-8	2016	Pretreatment with these inhibitors or transfection with MMP-9 siRNA also blocked thrombin-induced SK-N-SH cell migration.	sk-n-sh	98-105	coagulation factor II, thrombin	Homo sapiens	81-89
26474739-2	2015	In this study, we used human neuroblastoma cell line SK-N-SH as a model and first observed that inhibiting ACAT1 can decrease the amyloid precursor protein (APP)-alpha-processing.	sk-n-sh	53-60	acetyl-CoA acetyltransferase 1	Homo sapiens	107-112
26474739-2	2015	In this study, we used human neuroblastoma cell line SK-N-SH as a model and first observed that inhibiting ACAT1 can decrease the amyloid precursor protein (APP)-alpha-processing.	sk-n-sh	53-60	amyloid beta precursor protein	Homo sapiens	130-155
21901167-5	2011	Treatment of SK-N-SH with an ALK chemical inhibitor, TAE684, resulted in the outgrowth of S-type cells that expressed the Schwann cell marker, S100alpha6.	sk-n-sh	13-20	ALK receptor tyrosine kinase	Homo sapiens	29-32
20659427-7	2010	Hypoxia- and DEF-induced HIF-1alpha activation inhibited the TRAIL-mediated apoptosis in SK-N-SH, HeLa, A549 and SNU-638 cells.	sk-n-sh	89-96	UTP25 small subunit processome component	Homo sapiens	13-16
20659427-7	2010	Hypoxia- and DEF-induced HIF-1alpha activation inhibited the TRAIL-mediated apoptosis in SK-N-SH, HeLa, A549 and SNU-638 cells.	sk-n-sh	89-96	hypoxia inducible factor 1 subunit alpha	Homo sapiens	25-35
20659427-7	2010	Hypoxia- and DEF-induced HIF-1alpha activation inhibited the TRAIL-mediated apoptosis in SK-N-SH, HeLa, A549 and SNU-638 cells.	sk-n-sh	89-96	TNF superfamily member 10	Homo sapiens	61-66
18485949-8	2008	Granulocyte colony stimulating factor treatment resulted in significantly increased proliferation of SK-N-SH, SK-N-AS, and SHSY-5Y cells.	sk-n-sh	101-108	colony stimulating factor 3	Homo sapiens	0-37
15610155-3	2004	Microfluorometry assay demonstrated that CX(3)CR1 was functional in 44% of primary neurons and in 70% of SK-N-SH.	sk-n-sh	105-112	C-X3-C motif chemokine receptor 1	Homo sapiens	41-49
15336944-2	2004	KR-31378 restored TNF-alpha-induced decreased cell viability of SK-N-SH.	sk-n-sh	64-71	tumor necrosis factor	Homo sapiens	18-27
14995074-3	2003	SK-N-SH cell proliferation was inhibited byAMD3100 and anti-CXCL12 neutralizing antibodies, but enhanced by exogenously added CXCL12.	sk-n-sh	0-7	C-X-C motif chemokine ligand 12	Homo sapiens	60-66
14995074-3	2003	SK-N-SH cell proliferation was inhibited byAMD3100 and anti-CXCL12 neutralizing antibodies, but enhanced by exogenously added CXCL12.	sk-n-sh	0-7	C-X-C motif chemokine ligand 12	Homo sapiens	126-132
11741404-5	2001	In the present study, the neuronal cell line Sk-n-sh was incubated for 12 h with the cyclooxygenase inhibitor ibuprofen and subsequently stimulated with the cytokines TNFalpha and IFNgamma.	sk-n-sh	45-52	tumor necrosis factor	Homo sapiens	167-175
11741404-5	2001	In the present study, the neuronal cell line Sk-n-sh was incubated for 12 h with the cyclooxygenase inhibitor ibuprofen and subsequently stimulated with the cytokines TNFalpha and IFNgamma.	sk-n-sh	45-52	interferon gamma	Homo sapiens	180-188
10820436-3	2000	Monocyte adhesion to SK-N-SH but not SK-N-MC was partially inhibited by treating monocytes with a mAb to the CD18 (beta2) integrin chain.	sk-n-sh	21-28	lymphotoxin beta receptor	Homo sapiens	109-113
10820436-3	2000	Monocyte adhesion to SK-N-SH but not SK-N-MC was partially inhibited by treating monocytes with a mAb to the CD18 (beta2) integrin chain.	sk-n-sh	21-28	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	115-120
10820436-5	2000	Treatment of both NB cell lines with interleukin-1alpha (0.5 ng/ml), tumor necrosis factor alpha (100 U/ml), interferon gamma (200 U/ml), or their combinations increased monocyte adhesion to SK-N-SH and SK-N-MC.	sk-n-sh	191-198	interleukin 1 alpha	Homo sapiens	37-55
10820436-5	2000	Treatment of both NB cell lines with interleukin-1alpha (0.5 ng/ml), tumor necrosis factor alpha (100 U/ml), interferon gamma (200 U/ml), or their combinations increased monocyte adhesion to SK-N-SH and SK-N-MC.	sk-n-sh	191-198	tumor necrosis factor	Homo sapiens	69-96
26710786-0	2015	[Heat-shock protein HSP70 protects neuroblastoma cells SK-N-SH from the neurotoxic effects hydrogen peroxide and the beta-amyloid peptide].	sk-n-sh	55-62	heat shock protein family A (Hsp70) member 4	Homo sapiens	20-25
26710786-0	2015	[Heat-shock protein HSP70 protects neuroblastoma cells SK-N-SH from the neurotoxic effects hydrogen peroxide and the beta-amyloid peptide].	sk-n-sh	55-62	amyloid beta precursor protein	Homo sapiens	117-137
26710786-6	2015	In this study, we determined how HSP70 affected apoptosis and necrosis in human neuroblastoma cells SK-N-SH, induced by hydrogen peroxide and beta-amyloid peptide Abeta(1-42).	sk-n-sh	100-107	heat shock protein family A (Hsp70) member 4	Homo sapiens	33-38
26710786-6	2015	In this study, we determined how HSP70 affected apoptosis and necrosis in human neuroblastoma cells SK-N-SH, induced by hydrogen peroxide and beta-amyloid peptide Abeta(1-42).	sk-n-sh	100-107	amyloid beta precursor protein	Homo sapiens	142-162
26295826-7	2015	Long-term incubation of non-differentiated SK-N-SH with 1 muM ouabain led to a decrease in the number of cells; this effect was reduced in differentiated SK-N-SH cells.	sk-n-sh	43-50	latexin	Homo sapiens	58-61
25059665-7	2014	t-PA induces SK-N-SH cell proliferation via binding to GRP78 on the cell surface.	sk-n-sh	13-20	plasminogen activator, tissue type	Homo sapiens	0-4
25059665-7	2014	t-PA induces SK-N-SH cell proliferation via binding to GRP78 on the cell surface.	sk-n-sh	13-20	heat shock protein family A (Hsp70) member 5	Homo sapiens	55-60