PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
27510846-2	2016	In this respect, the targeting and ultrafast uptake of zeolite nanocrystals functionalized with Cetuximab antibodies (Ctxb) by cells overexpressing the epidermal growth factor receptor are described here.	ctxb	118-122	epidermal growth factor receptor	Homo sapiens	152-184
19299701-6	2009	Activation of Teff cells also up-regulated TRPC5 channels which mediated Ca(2+) influx upon GM1 cross-linking by Gal-1 or CtxB.	ctxb	122-126	transient receptor potential cation channel, subfamily C, member 5	Mus musculus	43-48
25809257-6	2015	We show that the diffusion rate of CTxB bound to GM1 is independent of the size of the confinement, suggesting that the mechanism of confinement is different from the mechanism controlling the diffusion rate of CtxB.	ctxb	35-39	coenzyme Q10A	Mus musculus	49-52
25809257-8	2015	We also show that aggregation of CTxB/GM1 in large complexes occurs and that these aggregates tend to have slower diffusion rates.	ctxb	33-37	coenzyme Q10A	Mus musculus	38-41
22511973-3	2012	In the current study, we used confocal FRAP to examine the origins of this slow diffusion of the CTxB/GM(1) complex at the cell surface, relative to the behavior of a representative GPI-anchored protein, transmembrane protein, and fluorescent lipid analog.	ctxb	97-101	mechanistic target of rapamycin kinase	Homo sapiens	39-43
21247801-1	2011	Analysis of 75 Vibrio cholerae O1 strains isolated from hospitalized patients in Kolkata from 1989 to 1994 revealed the existence of true El Tor along with El Tor variants that possessed the classical allele of ctxB (ctxB(cl)) in strains having an El Tor backbone.	ctxb	211-215	RAR related orphan receptor C	Homo sapiens	159-162
21247801-1	2011	Analysis of 75 Vibrio cholerae O1 strains isolated from hospitalized patients in Kolkata from 1989 to 1994 revealed the existence of true El Tor along with El Tor variants that possessed the classical allele of ctxB (ctxB(cl)) in strains having an El Tor backbone.	ctxb	211-215	RAR related orphan receptor C	Homo sapiens	159-162
21880975-9	2011	Notably, the sequencing of ctxB in some El Tor variants revealed two copies of classical ctxB, one per chromosome, contrary to previous reports that located ctxAB only on the large chromosome of El Tor biotype strains.	ctxb	27-31	RAR related orphan receptor C	Homo sapiens	43-46
19299701-8	2009	Short hairpin RNA (shRNA) knockdown of TRPC5 in Teff cells blocked contact-dependent proliferation inhibition by Treg cells as well as Gal-1/CtxB-triggered Ca(2+) influx.	ctxb	141-145	transient receptor potential cation channel, subfamily C, member 5	Mus musculus	39-44
17626205-3	2007	In this study, we demonstrate that CtxB-induced Ca2+ influx is mediated by TRPC5 channels, naturally expressed in these cells and primary neurons.	ctxb	35-39	transient receptor potential cation channel, subfamily C, member 5	Mus musculus	75-80
17626205-8	2007	Pharmacological blockers that inhibited tyrosine kinase, PLC, and PI(3)K suppressed both CtxB-induced Ca2+ influx and neurite outgrowth.	ctxb	89-93	perlecan (heparan sulfate proteoglycan 2)	Mus musculus	57-60
17626205-11	2007	In primary cerebellar granular neurons (CGNs), TRPC5 was detected at 2 d in vitro (2 DIV), a stage corresponding to CtxB-stimulated Ca2+ influx.	ctxb	116-120	transient receptor potential cation channel, subfamily C, member 5	Mus musculus	47-52