PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22983148-3	2012	Dicer cleaved the peptide-conjugated 27-nt siRNA leading to the release of 21-nt siRNA, whereas the peptide-conjugated 21-nt siRNA was not cleaved.	21-nt	75-80	dicer 1, ribonuclease III	Homo sapiens	0-5
28232389-6	2017	DRB7.1 also negates the action of DRB4 in enhancing accumulation of 21-nt siRNAs produced by DCL4.	21-nt	68-73	double-stranded-RNA-binding protein 4	Arabidopsis thaliana	34-38
28232389-6	2017	DRB7.1 also negates the action of DRB4 in enhancing accumulation of 21-nt siRNAs produced by DCL4.	21-nt	68-73	dicer-like 4	Arabidopsis thaliana	93-97
27982092-5	2016	In addition, although both drb4 and dcl4 single mutants permitted a consistent (but small) increase in viral RNA levels, the drb4 mutant correlated with a less pronounced reduction of 21-nt vsiRNAs.	21-nt	184-189	major histocompatibility complex, class II, DR beta 4	Homo sapiens	125-129
19359485-2	2009	We reported recently that 21-nt or longer small interfering RNAs (siRNAs) can suppress hemangiogenesis in mouse models of choroidal neovascularization and dermal wound healing independently of RNA interference by directly activating Toll-like receptor 3 (TLR3), a double-stranded RNA immune receptor, on the cell surface of blood endothelial cells.	21-nt	26-31	toll-like receptor 3	Mus musculus	233-253
20562854-5	2010	Using artificial miRNA constructs, conversion of asymmetric foldbacks to symmetric foldbacks resulted in the production of 21-nt forms of miR173, miR472 and miR828.	21-nt	123-128	MIR173	Arabidopsis thaliana	138-144
20562854-5	2010	Using artificial miRNA constructs, conversion of asymmetric foldbacks to symmetric foldbacks resulted in the production of 21-nt forms of miR173, miR472 and miR828.	21-nt	123-128	MIR472	Arabidopsis thaliana	146-152
20562854-5	2010	Using artificial miRNA constructs, conversion of asymmetric foldbacks to symmetric foldbacks resulted in the production of 21-nt forms of miR173, miR472 and miR828.	21-nt	123-128	MIR828	Arabidopsis thaliana	157-163
19359485-2	2009	We reported recently that 21-nt or longer small interfering RNAs (siRNAs) can suppress hemangiogenesis in mouse models of choroidal neovascularization and dermal wound healing independently of RNA interference by directly activating Toll-like receptor 3 (TLR3), a double-stranded RNA immune receptor, on the cell surface of blood endothelial cells.	21-nt	26-31	toll-like receptor 3	Mus musculus	255-259
19359485-3	2009	Here, we show that a 21-nt nontargeted siRNA suppresses both hemangiogenesis and lymphangiogenesis in mouse models of neovascularization induced by corneal sutures or hindlimb ischemia as efficiently as a 21-nt siRNA targeting vascular endothelial growth factor-A.	21-nt	21-26	vascular endothelial growth factor A	Mus musculus	227-263
19359485-5	2009	Exposure to 21-nt siRNA, which we demonstrate is not internalized unless cell-permeating moieties are used, triggers phosphorylation of cell surface TLR3 on lymphatic endothelial cells and induces apoptosis.	21-nt	12-17	toll-like receptor 3	Mus musculus	149-153
16103413-3	2005	In this study, a 21-nt synthetic small interfering RNA (siRNA; specifically designed to knockdown interleukin-8 [IL-8] expression) was delivered into HeLa cells.	21-nt	17-22	C-X-C motif chemokine ligand 8	Homo sapiens	98-111
16103413-3	2005	In this study, a 21-nt synthetic small interfering RNA (siRNA; specifically designed to knockdown interleukin-8 [IL-8] expression) was delivered into HeLa cells.	21-nt	17-22	C-X-C motif chemokine ligand 8	Homo sapiens	113-117
15788898-4	2005	Here, we report the synthesis of an antisense RNA inhibitor based on a new 21-nt sequence on a poly- DNP-RNA platform that can specifically inhibit cancer cell growth by silencing c-myc gene expression.	21-nt	75-80	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	180-185
12810955-4	2003	We directed 21-nt siRNAs against caspase 8, which is a key enzyme in death receptor-mediated apoptosis.	21-nt	12-17	caspase 8	Homo sapiens	33-42