PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 12324759-1 2002 BACKGROUND: The purpose of this study was to retrospectively evaluate technetium 99m tetrofosmin (Tc-TF) uptake in parathyroid adenomas and compare the results with their expression of multidrug resistance-mediated 170-kDa P-glycoprotein (Pgp). Technetium-99 70-83 ATP binding cassette subfamily B member 1 Homo sapiens 223-237 12324759-1 2002 BACKGROUND: The purpose of this study was to retrospectively evaluate technetium 99m tetrofosmin (Tc-TF) uptake in parathyroid adenomas and compare the results with their expression of multidrug resistance-mediated 170-kDa P-glycoprotein (Pgp). Technetium-99 70-83 ATP binding cassette subfamily B member 1 Homo sapiens 239-242 12126530-1 2002 OBJECTIVE: To investigate the relationship between the uptake of technetium-99m methoxyisobutyl isonitrile ((99m)Tc-MIBI) and the expression of multidrug resistance genes mdr-1 and MRP in lung cancer so as to guide chemotherapy. Technetium-99 65-78 ATP binding cassette subfamily B member 1 Homo sapiens 171-176 12146705-3 2002 Our purpose was to label an anti-CEA MoAb with technetium-99m (99Tc) and to validate a simplified animal model using a noncellular antigenic implant. Technetium-99 47-60 carcinoembryonic antigen gene family Mus musculus 33-36 12146705-3 2002 Our purpose was to label an anti-CEA MoAb with technetium-99m (99Tc) and to validate a simplified animal model using a noncellular antigenic implant. Technetium-99 63-67 carcinoembryonic antigen gene family Mus musculus 33-36 12126530-1 2002 OBJECTIVE: To investigate the relationship between the uptake of technetium-99m methoxyisobutyl isonitrile ((99m)Tc-MIBI) and the expression of multidrug resistance genes mdr-1 and MRP in lung cancer so as to guide chemotherapy. Technetium-99 65-78 ATP binding cassette subfamily C member 1 Homo sapiens 181-184 12077713-10 2002 Tc 99m HMPAO-labeled leukocyte scintigraphy should be considered in the evaluation of patients with SpA. Technetium-99 0-5 surfactant protein A2 Homo sapiens 100-103 11792176-3 2002 Such agents, when labeled with technetium-99m, might function as imaging agents for the dopamine transporter (DAT) system that would be useful for assessing the onset and severity of Parkinson"s disease. Technetium-99 31-44 solute carrier family 6 member 3 Homo sapiens 88-108 11914895-3 2002 Technetium-99m labelled monoclonal anti-NCA-90 granulocyte antibody Fab" fragment (MN3 Fab") has been shown to be useful in bone and joint infection, but there are no data specifically referring to low-grade bone infection. Technetium-99 0-13 FA complementation group B Homo sapiens 68-71 11914895-3 2002 Technetium-99m labelled monoclonal anti-NCA-90 granulocyte antibody Fab" fragment (MN3 Fab") has been shown to be useful in bone and joint infection, but there are no data specifically referring to low-grade bone infection. Technetium-99 0-13 FA complementation group B Homo sapiens 87-90 11970764-7 2002 Technetium 99m ((99m)Tc)-sestamibi, an agent in clinical use for myocardial perfusion and tumor imaging, is recognized as a substrate for Pgp and MRP, and has been used to visualize Pgp expression. Technetium-99 0-13 ATP binding cassette subfamily B member 1 Homo sapiens 138-141 11970764-7 2002 Technetium 99m ((99m)Tc)-sestamibi, an agent in clinical use for myocardial perfusion and tumor imaging, is recognized as a substrate for Pgp and MRP, and has been used to visualize Pgp expression. Technetium-99 0-13 ATP binding cassette subfamily C member 1 Homo sapiens 146-149 11970764-7 2002 Technetium 99m ((99m)Tc)-sestamibi, an agent in clinical use for myocardial perfusion and tumor imaging, is recognized as a substrate for Pgp and MRP, and has been used to visualize Pgp expression. Technetium-99 0-13 ATP binding cassette subfamily B member 1 Homo sapiens 182-185 11877745-0 2002 Alpha-melanocyte-stimulating hormone peptide analogs labeled with technetium-99m and indium-111 for malignant melanoma targeting. Technetium-99 66-79 pro-opiomelanocortin-alpha Mus musculus 0-36 11792176-3 2002 Such agents, when labeled with technetium-99m, might function as imaging agents for the dopamine transporter (DAT) system that would be useful for assessing the onset and severity of Parkinson"s disease. Technetium-99 31-44 solute carrier family 6 member 3 Homo sapiens 110-113 11393758-0 2001 Technetium-99m labelling of glycosylated somatostatin-14. Technetium-99 0-13 somatostatin Homo sapiens 41-56 11578909-2 2001 Gluconate has been used as exchange ligand in the carrier added experiments and in the syntheses of 99Tc-CCK(4) and Re-CCK(4) complexes to be able to reproduce at macroscopic level the same chemical reactions occurring at non carrier added conditions. Technetium-99 100-104 protein tyrosine kinase 7 (inactive) Homo sapiens 105-110 24578056-1 2001 The purpose of this study was to determine the biodistribution and the associated radiation dose of technetium-99m 4,5-bis(thioacetamido)pentanoyl-annexin-V ((99m)Tc-Apomate), a tracer proposed for the study of apoptosis. Technetium-99 100-113 annexin A5 Homo sapiens 147-156 10897007-3 2000 Scintigraphic breast images were obtained approximately 3-8 hours after the administration of technetium 99m ((99)Tc) labeled anti-CEA Fab" and correlated with histopathology. Technetium-99 94-107 CEA cell adhesion molecule 3 Homo sapiens 131-134 11189941-0 2000 Comparison of the accumulation and efflux kinetics of technetium-99m sestamibi and technetium-99m tetrofosmin in an MRP-expressing tumour cell line. Technetium-99 54-67 ATP binding cassette subfamily C member 3 Homo sapiens 116-119 11545187-0 2001 Binding rate constant of Tc-99m DTPA galactosyl human serum albumin measured by quantitative dynamic SPECT--clinical evaluation as a total and regional liver function test. Technetium-99 25-30 albumin Homo sapiens 54-67 11315596-0 2001 Assessment of leg oedema by dynamic lymphoscintigraphy with intradermal injection of technetium-99m human serum albumin and load produced by standing. Technetium-99 85-98 albumin Homo sapiens 106-119 11315596-1 2001 This study was a preliminary evaluation of the utility of dynamic lymphoscintigraphy with technetium-99m human serum albumin (HSA) and a load produced by standing in the assessment of lymphatic dysfunction in patients with leg oedema. Technetium-99 90-103 albumin Homo sapiens 111-124 11245443-0 2001 P-Glycoprotein and multidrug resistance-related protein expressions in relation to technetium-99m methoxyisobutylisonitrile scintimammography findings. Technetium-99 83-96 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 11245443-0 2001 P-Glycoprotein and multidrug resistance-related protein expressions in relation to technetium-99m methoxyisobutylisonitrile scintimammography findings. Technetium-99 83-96 chromosome 19 open reading frame 48 Homo sapiens 19-55 11321034-7 2001 Technetium-99m labeled annexin V localizes at sites of apoptosis in-vivo, due to its nanomolar affinity for membrane bound phosphatidylserine. Technetium-99 0-13 annexin A5 Homo sapiens 23-32 11177537-5 2001 We first labeled an adenovirus expressing human CFTR with the gamma-emitting radioisotope, technetium 99m (99mTc), and determined the best labeling conditions to allow preservation of virus bioactivity. Technetium-99 91-104 CF transmembrane conductance regulator Homo sapiens 48-52 11891611-1 2001 Our aim was to use technetium-99m tetrofosmin (Tc-TF) uptake in non-small cell lung cancer (NSCLC) for predicting the chemotherapeutic response of NSCLC to paclitaxel and to compare the results with the expression of multidrug resistance (MDR) - P-glycoprotein (Pgp). Technetium-99 19-32 ATP binding cassette subfamily B member 1 Homo sapiens 246-260 11891611-1 2001 Our aim was to use technetium-99m tetrofosmin (Tc-TF) uptake in non-small cell lung cancer (NSCLC) for predicting the chemotherapeutic response of NSCLC to paclitaxel and to compare the results with the expression of multidrug resistance (MDR) - P-glycoprotein (Pgp). Technetium-99 19-32 ATP binding cassette subfamily B member 1 Homo sapiens 262-265 11150712-0 2000 A CD(4)/T(4) receptor peptide ligand labeled with technetium-99m: synthesis and biological activity. Technetium-99 50-63 Cd4 molecule Rattus norvegicus 2-21 10959989-0 2000 Solid-phase extraction of technetium--amine complexes onto C18 silica and its application to the isolation of 99Tc The extraction of Tc-tripentylamine complexes onto C18 silica solid-phase extraction columns is evaluated for the selective removal of 99Tc from other isotopes. Technetium-99 110-114 Bardet-Biedl syndrome 9 Homo sapiens 166-169 10969653-5 2000 METHODS: Gene-modified ovarian cancer cells expressing the thymidine-kinase gene (PA1-STK) were radiolabeled with 99Tc and infused into the pleural space of 4 patients with malignant pleural mesothelioma, then scanned to determine distribution of the cells. Technetium-99 114-118 PAXIP1 associated glutamate rich protein 1 Homo sapiens 82-85 10897007-3 2000 Scintigraphic breast images were obtained approximately 3-8 hours after the administration of technetium 99m ((99)Tc) labeled anti-CEA Fab" and correlated with histopathology. Technetium-99 110-116 CEA cell adhesion molecule 3 Homo sapiens 131-134 10897007-3 2000 Scintigraphic breast images were obtained approximately 3-8 hours after the administration of technetium 99m ((99)Tc) labeled anti-CEA Fab" and correlated with histopathology. Technetium-99 110-116 FA complementation group B Homo sapiens 135-138 10779636-1 2000 We prospectively studied a total of 24 patients with breast cancer to evaluate the relationship between the degree of accumulation of technetium-99m sestamibi (Tc-99m MIBI) and p-glycoprotein (Pgp) expression in tumor tissues. Technetium-99 134-147 ATP binding cassette subfamily B member 1 Homo sapiens 177-191 10779636-1 2000 We prospectively studied a total of 24 patients with breast cancer to evaluate the relationship between the degree of accumulation of technetium-99m sestamibi (Tc-99m MIBI) and p-glycoprotein (Pgp) expression in tumor tissues. Technetium-99 134-147 ATP binding cassette subfamily B member 1 Homo sapiens 193-196 10741910-0 2000 Radioimmunodetection of residual, recurrent or metastatic germ cell tumors using technetium-99 anti-(alpha-fetoprotein) Fab" fragment. Technetium-99 81-94 alpha fetoprotein Homo sapiens 101-118 10928058-1 2000 We studied 30 patients with infiltrating ductal breast carcinomas to evaluate the relationship between the degree of accumulation of technetium-99m tetrofosmin (Tc-TETRO) and p-glycoprotein (Pgp) expression in breast tumor tissues. Technetium-99 133-146 ATP binding cassette subfamily B member 1 Homo sapiens 175-189 10741910-0 2000 Radioimmunodetection of residual, recurrent or metastatic germ cell tumors using technetium-99 anti-(alpha-fetoprotein) Fab" fragment. Technetium-99 81-94 FA complementation group B Homo sapiens 120-123 10515333-8 1999 mdr1 and mrp were associated with 99Tc-sestamibi washout, but their role in the parathyroid remains unclear. Technetium-99 34-38 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 10823326-9 2000 In vivo studies with 99Tc(m)-labelled annexin confirm that radiolabelled annexin V can be used to image apoptotic cells/tissues in vivo. Technetium-99 21-25 annexin A5 Homo sapiens 73-82 10515333-8 1999 mdr1 and mrp were associated with 99Tc-sestamibi washout, but their role in the parathyroid remains unclear. Technetium-99 34-38 ATP binding cassette subfamily C member 1 Homo sapiens 9-12 10472350-1 1999 The aim of this study was to investigate the relationship between Technetium-99m (Tc-99m) tetrofosmin accumulation in tumors which may represent the expression of multidrug resistance (MDR)--mediated P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP) as well as response to chemotherapy in patients with untreated small cell lung cancers (SCLC). Technetium-99 66-79 ATP binding cassette subfamily B member 1 Homo sapiens 200-214 10541822-0 1999 Technetium-99m HYNIC-annexin V: a potential radiopharmaceutical for the in-vivo detection of apoptosis. Technetium-99 0-13 annexin A5 Mus musculus 21-30 10541822-6 1999 We have coupled annexin V with the bifunctional hydrazinonicotinamide reagent (HYNIC) to prepare technetium-99m HYNIC-annexin V and demonstrated localization of radioactivity in tissues undergoing apoptosis in vivo. Technetium-99 97-110 annexin A5 Mus musculus 16-25 10541822-6 1999 We have coupled annexin V with the bifunctional hydrazinonicotinamide reagent (HYNIC) to prepare technetium-99m HYNIC-annexin V and demonstrated localization of radioactivity in tissues undergoing apoptosis in vivo. Technetium-99 97-110 annexin A5 Mus musculus 118-127 10436758-2 1999 Technetium-99m (Tc-99m) hexamethylpropylenamine (HMPAO) brain images were used to detect basal ganglion and cerebral cortex regional cerebral blood flow (rCBF) in patients with SLE with brain involvement. Technetium-99 0-13 CCAAT/enhancer binding protein zeta Rattus norvegicus 154-158 10541833-1 1999 Cerebral blood flow (CBF) has been quantified non-invasively using the brain perfusion index (BPI) determined from radionuclide angiographic data generated by technetium-99m hexamethylpropylene amine oxime( )((99m)Tc-HMPAO) or technetium-99m ethyl cysteinate dimer( )((99m)Tc-ECD). Technetium-99 159-172 bactericidal permeability increasing protein Homo sapiens 94-97 10429513-13 1999 Annexin V has been radiolabeled with Technetium-99m by direct coupling to free sulfhydryl groups, and through the hydrazinonicatinamide and N2S2 linking agents. Technetium-99 37-50 annexin A5 Homo sapiens 0-9 10472350-1 1999 The aim of this study was to investigate the relationship between Technetium-99m (Tc-99m) tetrofosmin accumulation in tumors which may represent the expression of multidrug resistance (MDR)--mediated P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP) as well as response to chemotherapy in patients with untreated small cell lung cancers (SCLC). Technetium-99 66-79 ATP binding cassette subfamily B member 1 Homo sapiens 216-219 10472350-1 1999 The aim of this study was to investigate the relationship between Technetium-99m (Tc-99m) tetrofosmin accumulation in tumors which may represent the expression of multidrug resistance (MDR)--mediated P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP) as well as response to chemotherapy in patients with untreated small cell lung cancers (SCLC). Technetium-99 66-79 ATP binding cassette subfamily C member 3 Homo sapiens 225-264 10472350-1 1999 The aim of this study was to investigate the relationship between Technetium-99m (Tc-99m) tetrofosmin accumulation in tumors which may represent the expression of multidrug resistance (MDR)--mediated P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP) as well as response to chemotherapy in patients with untreated small cell lung cancers (SCLC). Technetium-99 66-79 ATP binding cassette subfamily C member 3 Homo sapiens 266-269 10392376-1 1999 AIM: The purpose of this study was to assess the potential for radio-immunodetection (RAID) of murine anti-carcinoembryonic antigen (CEA) monoclonal antibody (MAb) F33-104 labeled with technetium-99m (99m-Tc) by a reduction-mediated labeling method. Technetium-99 185-198 carcinoembryonic antigen gene family Mus musculus 102-131 10392376-1 1999 AIM: The purpose of this study was to assess the potential for radio-immunodetection (RAID) of murine anti-carcinoembryonic antigen (CEA) monoclonal antibody (MAb) F33-104 labeled with technetium-99m (99m-Tc) by a reduction-mediated labeling method. Technetium-99 185-198 carcinoembryonic antigen gene family Mus musculus 133-136 9720670-0 1998 Alpha-1-antitrypsin labeling with technetium-99m for monitoring the deposition of alpha-1-antitrypsin in aerosol therapy. Technetium-99 34-47 serpin family A member 1 Homo sapiens 0-19 9586878-1 1998 PURPOSE: Since we have previously shown that the efflux rate of technetium 99m (99mTc) sestamibi, a transport substrate of P-glycoprotein (Pgp), is directly correlated with Pgp levels in untreated breast carcinoma, we tested whether tumor clearance of 9mTc-sestamibi may be predictive of therapeutic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. Technetium-99 64-77 ATP binding cassette subfamily B member 1 Homo sapiens 123-137 9600968-5 1998 In vivo localization of technetium 99m hydrazinonicotinamide-annexin V was tested in three models: fuminant hepatic apoptosis induced by anti-Fas antibody injection in BALB/c mice; acute rejection in ACI rats with transplanted heterotopic PVG cardiac allografts; and cyclophosphamide treatment of transplanted 38C13 murine B cell lymphomas. Technetium-99 24-37 annexin A5 Mus musculus 61-70 9586878-1 1998 PURPOSE: Since we have previously shown that the efflux rate of technetium 99m (99mTc) sestamibi, a transport substrate of P-glycoprotein (Pgp), is directly correlated with Pgp levels in untreated breast carcinoma, we tested whether tumor clearance of 9mTc-sestamibi may be predictive of therapeutic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. Technetium-99 64-77 ATP binding cassette subfamily B member 1 Homo sapiens 139-142 9586878-1 1998 PURPOSE: Since we have previously shown that the efflux rate of technetium 99m (99mTc) sestamibi, a transport substrate of P-glycoprotein (Pgp), is directly correlated with Pgp levels in untreated breast carcinoma, we tested whether tumor clearance of 9mTc-sestamibi may be predictive of therapeutic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. Technetium-99 64-77 ATP binding cassette subfamily B member 1 Homo sapiens 173-176 9443738-14 1998 CONCLUSION: A recombinant MET containing scFv was successfully expressed, purified and labeled with 99Tc. Technetium-99 100-104 immunglobulin heavy chain variable region Homo sapiens 41-45 9021109-1 1997 A multicentre study on multicompartmental analysis of hepatic scintigraphy using technetium-99m labelled galactosyl serum albumin (GSA), which binds to the asialoglycoprotein receptor, was carried out at seven institutions in Japan. Technetium-99 81-94 albumin Homo sapiens 116-129 9380538-0 1997 Technetium-99m labelling of the IOR CEA 1 monoclonal antibody: evaluation of different methods. Technetium-99 0-13 carcinoembryonic antigen-related cell adhesion molecule 1 Mus musculus 36-41 9259962-6 1997 Ten patients with elevated carcinoembryonic antigen (CEA) levels and no CT findings had a scintigraphy scan with an anti-CEA MoAb labeled with 99Tc. Technetium-99 143-147 CEA cell adhesion molecule 3 Homo sapiens 121-124 9129773-7 1997 Tc 99m imaging of intraperitoneal catheters for insulin delivery can be used to assess catheter patency and impaired delivery into the peritoneal cavity. Technetium-99 0-5 insulin Homo sapiens 48-55 9227788-4 1997 Therefore, the current study evaluates the potential use of a new monoclonal antibody-based imaging agent, arcitumomab (CEA-Scan), which comprises an anti-carcinoembryonic antigen monoclonal antibody Fab" fragment labeled directly with technetium-99m, in the detection of primary, recurrent, or metastatic mammary cancer. Technetium-99 236-249 CEA cell adhesion molecule 3 Homo sapiens 120-123 8662095-0 1996 Value of radioimmunoscintigraphy with technetium-99m labelled anti-CEA monoclonal antibody (BW431/26) in the detection of colorectal cancer. Technetium-99 38-51 CEA cell adhesion molecule 3 Homo sapiens 67-70 8662095-0 1996 Value of radioimmunoscintigraphy with technetium-99m labelled anti-CEA monoclonal antibody (BW431/26) in the detection of colorectal cancer. Technetium-99 38-51 BW26 Homo sapiens 92-100 8662095-2 1996 Technetium-99m labelled BW431/26, a monoclonal antibody against carcinoembryonic antigen (CEA), was used. Technetium-99 0-13 BW26 Homo sapiens 24-32 8662095-2 1996 Technetium-99m labelled BW431/26, a monoclonal antibody against carcinoembryonic antigen (CEA), was used. Technetium-99 0-13 CEA cell adhesion molecule 3 Homo sapiens 64-88 8662095-2 1996 Technetium-99m labelled BW431/26, a monoclonal antibody against carcinoembryonic antigen (CEA), was used. Technetium-99 0-13 CEA cell adhesion molecule 3 Homo sapiens 90-93 8586081-2 1995 We compared different indices of transit time in a group of 30 patients having baseline and ACE inhibitor technetium-99m mercaptoacetyltriglycine (MAG3) renography prior to arteriography: peak time, mean transit time, and the ratio of background-subtracted counts at 20 min to those at 3 min. Technetium-99 106-119 angiotensin I converting enzyme Homo sapiens 92-95 8691466-0 1996 Somatostatin receptor-binding peptides labeled with technetium-99m: chemistry and initial biological studies. Technetium-99 52-65 somatostatin receptor 3 Rattus norvegicus 0-21 8692479-1 1996 The aim of this study was to make a comparative evaluation of a direct and an indirect method for the labelling of anti-CEA with technetium-99m (99Tcm). Technetium-99 129-142 CEA cell adhesion molecule 3 Homo sapiens 120-123 7493340-9 1995 The tumor uptake of 99Tc-labeled anti-carcinoembryonic antigen antibody was increased approximately 2-fold in rats pretreated with 70 micrograms of CA19-9-CVF, compared to animals that received an equimolar mixture of noncoupled mab and CVF. Technetium-99 20-24 CEA cell adhesion molecule 20 Rattus norvegicus 38-62 8586084-2 1995 We evaluated the possibility of using an anti-serine protease (aprotinin) labelled with technetium-99m (TcA), usually employed as a cortical renal tracer, for the imaging of amyloid deposits. Technetium-99 88-101 coagulation factor II, thrombin Homo sapiens 46-61 8355083-0 1993 Uptake of technetium-99m MDP in primary amyloidosis with a review of the mechanisms of soft tissue localization of bone seeking radiopharmaceuticals. Technetium-99 10-23 dipeptidase 1 Homo sapiens 25-28 7588942-0 1995 Upregulation of granulocyte CD11b (CR 3) after labelling with technetium-99m hexamethylpropylene amine oxime. Technetium-99 62-75 integrin subunit alpha M Homo sapiens 28-33 7588942-0 1995 Upregulation of granulocyte CD11b (CR 3) after labelling with technetium-99m hexamethylpropylene amine oxime. Technetium-99 62-75 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 35-39 7828603-5 1994 Scans were performed following intraperitoneal administration of 500-1000 ml of 99Tc-labeled human serum albumin in normal saline. Technetium-99 80-84 albumin Homo sapiens 105-112 8491449-1 1993 Technetium 99m diethylenetriaminepentaacetic acid-galactosyl human serum albumin is a newly developed analog ligand to asialoglycoprotein receptor, which is a hepatic cell surface receptor specific for galactose-terminated glycoproteins. Technetium-99 0-13 albumin Homo sapiens 67-80 8339729-0 1993 Technetium-99m labelled human serum albumin for ventriculography: a comparative evaluation of six labelling kits. Technetium-99 0-13 albumin Mus musculus 30-43 8491449-7 1993 We conclude that the parameter, asialoglycoprotein receptor concentration, obtained from the kinetic analysis of technetium 99m diethylenetriaminepentaacetic acid-galactosyl human serum albumin time-activity data, is a sensitive measure of functioning hepatocyte mass in acute and chronic liver disease. Technetium-99 113-126 albumin Homo sapiens 180-193 8391686-3 1993 To address this issue, we conducted an in vitro, randomized, single-blind study using fenoterol MDI containing technetium-99m pertechnetate. Technetium-99 111-124 MAFD2 Homo sapiens 96-99 8486395-0 1993 Technetium-99 m labelling of DD-3B6/22 antifibrin monoclonal antibody fragment Fab" for thrombus imaging. Technetium-99 0-13 FA complementation group B Homo sapiens 79-82 1730981-0 1992 An instant kit method for labeling antimyosin Fab" with technetium-99m: evaluation in an experimental myocardial infarct model. Technetium-99 56-69 FA complementation group B Homo sapiens 46-49 8404953-3 1993 The purpose of this study was to determine whether the hepatic uptake of dialysed technetium-99m labelled low-density lipoprotein (99mTc-LDL) reflects the hepatic LDL receptor activity and to what extent the non-LDL receptor-dependent 99mTc-LDL uptake by non-parenchymal cells relates to the diagnostic utility of quantitative 99mTc-LDL scintigraphy of the liver. Technetium-99 82-95 low-density lipoprotein receptor Oryctolagus cuniculus 163-175 8404956-2 1993 Technetium-99m radiolabelled 1A3, a monoclonal antibody against a columnar cell surface antigen, was used. Technetium-99 0-13 CD53 molecule Homo sapiens 75-95 1311185-2 1992 A retrospective review of a large series of patients with urinary tract disorders at the hospital for Sick Children, Great Ormond Street, identified 12 patients with vesico-ureteric reflux (VUR) with no evidence of scarring but with renal damage as assessed using technetium 99m dimercaptosuccinic acid (99mTc-DMSA) scan. Technetium-99 264-277 VUR Homo sapiens 190-193 2040339-0 1991 The APE nebuliser--a new delivery system for the alveolar targeting of particulate technetium 99m diethylene triamine penta-acetic acid. Technetium-99 83-96 apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens 4-7 2087823-2 1990 First promising results were obtained with Technetium-99m labelled murine monoclonal antibodies against carcinoembryonic antigen (CEA). Technetium-99 43-56 CEA cell adhesion molecule 3 Homo sapiens 104-128 2087823-2 1990 First promising results were obtained with Technetium-99m labelled murine monoclonal antibodies against carcinoembryonic antigen (CEA). Technetium-99 43-56 CEA cell adhesion molecule 3 Homo sapiens 130-133 2164650-1 1990 Technetium-99m (99Tcm)(V) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to evaluate squamous carcinoma (SCC) of the head and neck. Technetium-99 0-13 serpin family B member 3 Homo sapiens 139-142 2166552-0 1990 Immunoscintigraphy using a technetium-99m labelled monoclonal anti-CEA antibody in the follow-up of colorectal cancer and other tumours producing CEA. Technetium-99 27-40 CEA cell adhesion molecule 3 Homo sapiens 67-70 2166552-0 1990 Immunoscintigraphy using a technetium-99m labelled monoclonal anti-CEA antibody in the follow-up of colorectal cancer and other tumours producing CEA. Technetium-99 27-40 CEA cell adhesion molecule 3 Homo sapiens 146-149 2162508-1 1990 Technetium-99m (99Tcm) (v) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to image medullary carcinoma of the thyroid and squamous cell carcinoma (SCC) of the head and neck. Technetium-99 0-13 serpin family B member 3 Homo sapiens 181-184 2162509-1 1990 Technetium-99m (99Tcm) (v) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to image squamous cell carcinoma (SCC) of the head and neck. Technetium-99 0-13 serpin family B member 3 Homo sapiens 142-145 34596116-2 2021 We aimed to evaluate the DAT binding potential (DAT-BP) in a sample of healthy Brazilians through technetium-99 metastable TRODAT-1 single-photon emission computed tomography imaging.We selected 126 healthy individuals comprising 72 men and 54 women, aged 18 to 80 years. Technetium-99 98-111 solute carrier family 6 member 3 Homo sapiens 25-28 34823954-1 2022 This study investigates the impacts of Ni doping on technetium-99 (Tc) sequestration in aqueous solutions through transformation of Fe(OH)2(s) to iron spinel (magnetite) under alkaline conditions. Technetium-99 52-65 general transcription factor IIE subunit 1 Homo sapiens 132-139 34823954-1 2022 This study investigates the impacts of Ni doping on technetium-99 (Tc) sequestration in aqueous solutions through transformation of Fe(OH)2(s) to iron spinel (magnetite) under alkaline conditions. Technetium-99 67-69 general transcription factor IIE subunit 1 Homo sapiens 132-139 34823954-8 2022 The finding of the metallic Tc encapsulation indicates that Tc sequestration through Ni-doped Fe(OH)2(s)-to-iron spinel transformation process likely provides an alternative treatment pathway for Tc removal and could be combined into further waste treatment approaches. Technetium-99 28-30 general transcription factor IIE subunit 1 Homo sapiens 94-101 34823954-8 2022 The finding of the metallic Tc encapsulation indicates that Tc sequestration through Ni-doped Fe(OH)2(s)-to-iron spinel transformation process likely provides an alternative treatment pathway for Tc removal and could be combined into further waste treatment approaches. Technetium-99 60-62 general transcription factor IIE subunit 1 Homo sapiens 94-101 34823954-8 2022 The finding of the metallic Tc encapsulation indicates that Tc sequestration through Ni-doped Fe(OH)2(s)-to-iron spinel transformation process likely provides an alternative treatment pathway for Tc removal and could be combined into further waste treatment approaches. Technetium-99 196-198 general transcription factor IIE subunit 1 Homo sapiens 94-101 1964640-0 1990 Reduced technetium 99m labelled NCA-95/CEA-antibody uptake in liver due to gentle antibody reconstitution. Technetium-99 8-21 CEA cell adhesion molecule 8 Homo sapiens 32-38 2586133-2 1989 Albumin aggregates (15 to 30 microns) labeled with technetium 99m were injected into the left ventricle during bypass (ventricle), the perfusion cannula during bypass (cannula), and the left ventricle with no bypass (control). Technetium-99 51-64 albumin Oryctolagus cuniculus 0-7 3581620-0 1987 Exercise-induced muscle uptake of technetium-99m MDP. Technetium-99 34-47 dipeptidase 1 Homo sapiens 49-52 2495819-2 1989 The kinetic behavior of fibrin clot lysis as induced by tissue-type plasminogen activator (t-PA) was studied using proton magnetic resonance (PMR) and a release assay of fibrin labeled with technetium-99m isotope (99mTc). Technetium-99 190-203 plasminogen activator, tissue type Homo sapiens 91-95 2544690-1 1989 A recently developed imaging agent, technetium-99m (v) dimercaptosuccinic acid (99mTc (v) DMSA), has been used to assess head and neck squamous carcinoma (SCC). Technetium-99 36-49 serpin family B member 3 Homo sapiens 155-158 2972815-1 1988 Technetium-99m isonitrile myocardial perfusion imaging was employed in a patient undergoing thrombolytic therapy with recombinant tissue plasminogen activator for acute anteroseptal myocardial infarction. Technetium-99 0-13 chromosome 20 open reading frame 181 Homo sapiens 130-158 3168364-0 1988 Diffuse muscle uptake of technetium-99M MDP in a patient with lung cancer. Technetium-99 25-38 dipeptidase 1 Homo sapiens 40-43 7131084-0 1982 Technetium-99m labeling of antibodies to cardiac myosin Fab and to human fibrinogen. Technetium-99 0-13 fibrinogen beta chain Homo sapiens 73-83 2822624-4 1987 These results indicate that the two 99Tc (NEP-DADT) complexes are syn and anti isomers (i.e. one isomer has the N-piperdinylethyl side chain located syn to the technetium oxo core while the other has this side chain located anti to the technetium oxo core). Technetium-99 36-40 synemin Homo sapiens 66-69 2822624-4 1987 These results indicate that the two 99Tc (NEP-DADT) complexes are syn and anti isomers (i.e. one isomer has the N-piperdinylethyl side chain located syn to the technetium oxo core while the other has this side chain located anti to the technetium oxo core). Technetium-99 36-40 synemin Homo sapiens 149-152 3698433-0 1986 Extraosseous uptake of technetium-99m MDP in secondary deposits of neuroblastoma. Technetium-99 23-36 dipeptidase 1 Homo sapiens 38-41 4075669-0 1985 Dermal uptake of technetium-99m MDP in calcinosis cutis. Technetium-99 17-30 dipeptidase 1 Homo sapiens 32-35 3902390-3 1985 It is concluded that radionuclide angiocardiography with technetium 99m macroaggregated albumin (99mTc MAA), followed immediately by a perfusion lung scan, may have a place in the evaluation of patients with refractory hypoxemia, since pulmonary embolism and/or right-to-left shunting are two of several causes of hypoxemia in the absence of congenital heart disease. Technetium-99 57-70 MAA Homo sapiens 103-106 6469268-2 1984 R11D10 Fab with a Ka of 5 X 10(8) M-1 was labeled with technetium-99m (99mTc) by the dithionite reduction method of technetium pertechnetate, via a bifunctional chelating agent, diethylene triamine pentaacetic acid (DTPA). Technetium-99 55-68 FA complementation group B Homo sapiens 7-10 5712340-0 1968 [Apropos of the use of human serum albumin labeled with technetium 99m in placental and pulmonary scintigraphy]. Technetium-99 56-69 albumin Homo sapiens 35-42 5128133-0 1971 Pulmonary scanning using technetium 99m labeled macroaggregates of albumin prepared according to a new and simplified technique. Technetium-99 25-38 albumin Homo sapiens 67-74 6155355-0 1980 The valence state of technetium-99 in its complexes with bleomycin, 1-hydroxy-ethylidene-1,1-diphosphonate and human serum albumin. Technetium-99 21-34 albumin Homo sapiens 117-130 11496383-0 1979 [Evaluation of bone scintigraphy with pyrophosphate and fibrinogen labeled with technetium 99m in rheumatoid arthritis and other arthropathies]. Technetium-99 80-93 fibrinogen beta chain Homo sapiens 56-66 499236-1 1979 We have investigated the suitability of five different commercially available kits which provide human serum albumin (HSA) labelled with technetium 99m (99mTc) for cardiac blood pool imaging. Technetium-99 137-150 albumin Homo sapiens 103-116 140151-0 1977 Labeling plasmin with technetium-99m for scintigraphic localization of thrombi. Technetium-99 22-35 plasminogen Homo sapiens 9-16 790607-0 1976 Dynamic scintiscanning with technetium-99m as a diagnostic aid in oliguria after renal transplant. Technetium-99 28-41 activation induced cytidine deaminase Homo sapiens 59-62 33642158-0 2021 Tumor-to-Normal Ratio Relationship between Planning Technetium-99 Macroaggregated Albumin and Posttherapy Yttrium-90 Bremsstrahlung SPECT/CT. Technetium-99 52-65 albumin Homo sapiens 82-89 31432660-6 2019 99Tc(VII) is more easily reduced than Re(VII) in the presence of NO3- with very slow redissolution of reduced 99Tc. Technetium-99 0-4 NBL1, DAN family BMP antagonist Homo sapiens 65-68 33259032-3 2020 Technetium-99 m [99mTc]-labelled anti-PD-L1 single-domain antibody (NM-01) SPECT/CT quantification correlates with PD-L1 expression in NSCLC, presenting an opportunity for non-invasive assessment. Technetium-99 0-13 CD274 molecule Homo sapiens 38-43 33259032-3 2020 Technetium-99 m [99mTc]-labelled anti-PD-L1 single-domain antibody (NM-01) SPECT/CT quantification correlates with PD-L1 expression in NSCLC, presenting an opportunity for non-invasive assessment. Technetium-99 0-13 CD274 molecule Homo sapiens 115-120 33906800-7 2021 In the first part of the review, we report on the diagnostic efficacy of various PSMA imaging radiotracers labeled with gallium-68, fluorine-18, and technetium-99m. Technetium-99 149-162 folate hydrolase 1 Homo sapiens 81-85 31234464-6 2019 SPECT/CT imaging in mice following intravenous injection of Technetium-99m (99mTc)-labeled sdAb K2 revealed high signal-to-noise ratios, strong ability to specifically detect PD-L1 in melanoma and breast tumors, and relatively low kidney retention, which is a unique property for radiolabeled sdAbs. Technetium-99 60-73 CD274 antigen Mus musculus 175-180 30843155-0 2019 Impaired brain dopamine transporter in chemobrain patients submitted to brain SPECT imaging using the technetium-99m labeled tracer TRODAT-1. Technetium-99 102-115 solute carrier family 6 member 3 Homo sapiens 15-35 30325581-1 2019 It has been suggested that technetium-99m (99mTc)-anti-tumour necrosis factor alpha (TNF-alpha) scintigraphy (SCI) may be a useful diagnostic tool in Graves" ophthalmopathy (GO). Technetium-99 27-40 tumor necrosis factor Homo sapiens 85-94 30250607-1 2018 The present study aimed to label ZHER2:V2 with technetium-99m (99mTc) using a simple method and to evaluate its clinical potential as a diagnostic probe for human epidermal growth factor receptor type 2 (HER2)-positive tumors. Technetium-99 47-60 erb-b2 receptor tyrosine kinase 2 Homo sapiens 34-38 30421571-0 2019 Effect of technetium-99 conjugated with methylene diphosphonate (99 Tc-MDP) on OPG/RANKL/RANK system in vitro. Technetium-99 10-23 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus 79-82 30421571-0 2019 Effect of technetium-99 conjugated with methylene diphosphonate (99 Tc-MDP) on OPG/RANKL/RANK system in vitro. Technetium-99 10-23 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 83-88 30650563-0 2019 Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m. Technetium-99 116-129 cholecystokinin B receptor Homo sapiens 0-26 30843003-14 2019 Such a single occult metastasis causing very high levels of PSA has been presented using technetium-99m (99m Tc) labeled PSMA imaging. Technetium-99 89-102 kallikrein related peptidase 3 Homo sapiens 60-63 30843003-14 2019 Such a single occult metastasis causing very high levels of PSA has been presented using technetium-99m (99m Tc) labeled PSMA imaging. Technetium-99 89-102 folate hydrolase 1 Homo sapiens 121-125 30324468-1 2019 BACKGROUND: This study evaluated the effect of technetium-99m (99mTc)-labeled prostate-specific membrane antigen (PSMA)-based image-guided surgery on the oncologic outcomes for patients with primary or recurrent prostate cancer (PCa). Technetium-99 47-60 folate hydrolase 1 Homo sapiens 78-112 30324468-1 2019 BACKGROUND: This study evaluated the effect of technetium-99m (99mTc)-labeled prostate-specific membrane antigen (PSMA)-based image-guided surgery on the oncologic outcomes for patients with primary or recurrent prostate cancer (PCa). Technetium-99 47-60 folate hydrolase 1 Homo sapiens 114-118 30406140-1 2018 Technetium-99 conjugated with methylene diphosphonate (99Tc-MDP) is an effective anti-inflammatory drug in treating rheumatoid arthritis (RA) for over 15 years in China. Technetium-99 0-13 dipeptidase 1 Homo sapiens 60-63 30301182-4 2018 The aim of this work was to study physico-chemical and biological properties of different SP analogues labeled with technetium-99m and lutetium-177 radionuclides. Technetium-99 116-129 tachykinin precursor 1 Homo sapiens 90-92 30165015-3 2018 Here, we show that natural H-ferritin nanocages radiolabeled with technetium-99m (99mTc-HFn) can identify and accurately localize macrophage-rich, atherosclerotic plaques in living mice using combined SPECT and CT. Focal 99mTc-HFn uptake was observed in the atherosclerotic plaques with multiple high-risk features of macrophage infiltration, active calcification, positive remodeling, and necrosis on histology and in early active ongoing lesions with intense macrophage infiltration. Technetium-99 66-79 ferritin heavy polypeptide 1 Mus musculus 27-37 29864241-4 2018 We radiolabeled the CFTR inhibitor, CFTRinh -172a, with technetium-99m via a pyrazolyl-diamine chelating unit, yielding a novel 99m Tc(CO)3 complex. Technetium-99 56-69 CF transmembrane conductance regulator Homo sapiens 20-24 27937056-2 2017 METHOD: We compared the results of scintigraphy and MRI in two patients with psoriatic arthritis who underwent technetium-99m (99mTc)-anti-TNF-alpha scintigraphy, and MRI 5 days later. Technetium-99 111-124 tumor necrosis factor Homo sapiens 139-148 28925879-0 2018 Human Fibronectin Extra-Domain B (EDB)-Specific Aptide (APTEDB) Radiolabelling with Technetium-99m as a Potent Targeted Tumour-Imaging Agent. Technetium-99 84-97 fibronectin 1 Homo sapiens 18-32 28925879-0 2018 Human Fibronectin Extra-Domain B (EDB)-Specific Aptide (APTEDB) Radiolabelling with Technetium-99m as a Potent Targeted Tumour-Imaging Agent. Technetium-99 84-97 fibronectin 1 Homo sapiens 34-37 27981470-6 2017 PROCEDURES: Mouse IgG without specificity to biomolecules was labeled with technetium-99m via 6-hydrazinonicotinate to yield [99mTc]IgG. Technetium-99 75-88 immunoglobulin heavy variable V1-62 Mus musculus 18-21 27981470-6 2017 PROCEDURES: Mouse IgG without specificity to biomolecules was labeled with technetium-99m via 6-hydrazinonicotinate to yield [99mTc]IgG. Technetium-99 75-88 immunoglobulin heavy variable V1-62 Mus musculus 132-135 27998671-0 2017 Synthesis, physicochemical and biological studies of technetium-99m labeled tacrine derivative as a diagnostic tool for evaluation of cholinesterase level. Technetium-99 53-66 butyrylcholinesterase Homo sapiens 134-148 28586008-3 2017 In the present study, the targeting effects of an anti-CEA nanobody obtained from phage display were investigated using technetium-99 m (99mTc) and fluorescence labeling. Technetium-99 120-133 CEA cell adhesion molecule 3 Homo sapiens 55-58 26954010-1 2016 Purpose To examine the relation between the lung elimination rate of inhaled technetium 99m ((99m)Tc)-sestamibi and immunohistochemical expression of bronchopulmonary multidrug resistance protein 1 (MRP1) and permeability glycoprotein (P-gp) and assess the repeatability of the inhaled (99m)Tc-sestamibi clearance technique. Technetium-99 77-90 ATP binding cassette subfamily B member 1 Homo sapiens 167-197 27635026-7 2017 Putting hNIS under a late synthetic promoter allowed a higher functional expression of the protein and much stronger 123I or 99Tc uptake. Technetium-99 125-129 solute carrier family 5 member 5 Homo sapiens 8-12 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). Technetium-99 167-180 t-complex 1 Homo sapiens 64-69 26923781-4 2016 OBJECTIVE: The aim of this study was to evaluate the biodistribution of Technetium-99m (99mTc)-Aprotinin solution (99mTc-Aprotinin-S) and 99mTc-Aprotinin loaded microemulsion, which was prepared for the aim of treatment for acute pancreatitis. Technetium-99 72-85 pancreatic trypsin inhibitor Bos taurus 95-104 26954010-1 2016 Purpose To examine the relation between the lung elimination rate of inhaled technetium 99m ((99m)Tc)-sestamibi and immunohistochemical expression of bronchopulmonary multidrug resistance protein 1 (MRP1) and permeability glycoprotein (P-gp) and assess the repeatability of the inhaled (99m)Tc-sestamibi clearance technique. Technetium-99 77-90 ATP binding cassette subfamily B member 1 Homo sapiens 199-203 27459001-3 2016 With the goal of preparing technetium-99(m) complexes that bind to Abeta plaques with the potential to be diagnostic imaging agents for Alzheimer"s disease, new tetradentate ligands capable of forming neutral and lipophilic complexes with oxotechentium(V) and oxorhenium(V) were prepared. Technetium-99 27-40 amyloid beta precursor protein Homo sapiens 67-72 26657217-1 2016 The labeling of leukocytes with technetium-99m (Tc)-HMPAO is a frequent procedure in our laboratory, which was first validated before initiation of clinical studies with the commercial kit of Tc-D,L-hexamethylpropylene amine oxime (Tc-D,L-HMPAO), available from 1988. Technetium-99 32-45 CHM Rab escort protein Homo sapiens 192-196 27246977-1 2016 PURPOSE: We aimed to develop and translate a CD20-antigen-targeted radiopharmaceutical, Technetium-99 m-labeled (99mTc) rituximab, for sentinel lymph node (SLN) detection. Technetium-99 88-101 keratin 20 Homo sapiens 45-49 27073620-1 2016 Technetium 99 conjugated with methylene diphosphonate, which is an anti-inflammatory drug, can inhibit macrophage infiltration and downregulate a number of proinflammatory cytokines, such as tumor necrosis factor-alpha and interleukin-1beta. Technetium-99 0-13 tumor necrosis factor Homo sapiens 191-218 27073620-1 2016 Technetium 99 conjugated with methylene diphosphonate, which is an anti-inflammatory drug, can inhibit macrophage infiltration and downregulate a number of proinflammatory cytokines, such as tumor necrosis factor-alpha and interleukin-1beta. Technetium-99 0-13 interleukin 1 beta Homo sapiens 223-240 26657217-1 2016 The labeling of leukocytes with technetium-99m (Tc)-HMPAO is a frequent procedure in our laboratory, which was first validated before initiation of clinical studies with the commercial kit of Tc-D,L-hexamethylpropylene amine oxime (Tc-D,L-HMPAO), available from 1988. Technetium-99 32-45 CHM Rab escort protein Homo sapiens 232-236 25537093-1 2015 PURPOSE: Technetium-99 m (Tc-99 m)-labelled microparticles, functionalized with fucoidan to present a high affinity for P-Selectin, or [(99m)Tc] MP-fucoidan, were developed as a novel SPECT radiotracer for abdominal aortic aneurysm (AAA). Technetium-99 9-22 selectin P Homo sapiens 120-130 26792952-3 2016 The distribution ratios of 99Tc with lower than +VII oxidation state ionic species between 4 M H2SO4 and 30 % TBP/kerosene were found and are significantly lower than for TcO4- in the same solution. Technetium-99 27-31 TATA-box binding protein Homo sapiens 110-113 26622829-3 2015 The present study aimed to develop a technetium-99m (99mTc)-labeled uPAR-binding peptide for non-invasive single-photon emission computed tomography (SPECT) assessment of uPAR expression in pancreatic cancer xenograft models. Technetium-99 37-50 plasminogen activator, urokinase receptor Homo sapiens 68-72 26622829-3 2015 The present study aimed to develop a technetium-99m (99mTc)-labeled uPAR-binding peptide for non-invasive single-photon emission computed tomography (SPECT) assessment of uPAR expression in pancreatic cancer xenograft models. Technetium-99 37-50 plasminogen activator, urokinase receptor Homo sapiens 171-175 25440878-0 2014 Synthesis, physicochemical and biological evaluation of technetium-99m labeled lapatinib as a novel potential tumor imaging agent of Her-2 positive breast cancer. Technetium-99 56-69 erb-b2 receptor tyrosine kinase 2 Homo sapiens 133-138 23763985-1 2013 Technetium 99m (99mTc)-annexin A5, a marker of ongoing apoptosis, is supposed to be useful in the detection of metabolically active atheroma. Technetium-99 0-13 annexin A5 Mus musculus 23-33 25397621-2 2014 Methylene diphosphonate-technetium-99m ((99m)Tc-MDP) 3-phase bone scan is considered the most sensitive imaging method for the detection of jaw osteonecrosis at an early stage. Technetium-99 24-37 dipeptidase 1 Homo sapiens 48-51 23759825-0 2014 An estimate of the inventory of technetium-99 in the sub-tidal sediments of the Irish Sea. Technetium-99 32-45 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 86-89 23759825-1 2014 Published results from earlier studies have provided indications that measurable quantities of technetium-99 ((99)Tc) have accumulated in the sub-tidal sediments of the Irish Sea. Technetium-99 95-108 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 175-178 23013134-0 2012 Technetium-99 conjugated with methylene diphosphonate inhibits receptor activator of nuclear factor-kappaB ligand-induced osteoclastogenesis. Technetium-99 0-13 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 63-113 23465564-0 2013 Preliminary studies of acetylcholinesterase activity in the rat brain using N-phenylferrocenecarboxamide labelled by the technetium-99m. Technetium-99 121-134 acetylcholinesterase Rattus norvegicus 23-43 23013134-2 2012 In the present study, we investigated the effects of technetium-99 conjugated with methylene diphosphonate ((99)Tc-MDP), an agent used in radionuclide therapy, on receptor activator of nuclear factor-kappaB ligand (RANKL)-induced osteoclastogenesis and explored the underlying mechanisms. Technetium-99 53-66 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 163-213 23013134-2 2012 In the present study, we investigated the effects of technetium-99 conjugated with methylene diphosphonate ((99)Tc-MDP), an agent used in radionuclide therapy, on receptor activator of nuclear factor-kappaB ligand (RANKL)-induced osteoclastogenesis and explored the underlying mechanisms. Technetium-99 53-66 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 215-220 22469241-1 2012 As apoptosis occurs over an interval of time after administration of apoptosis-inducing therapy in tumors, the changes in technetium 99m ((99m)Tc)-tricarbonyl (CO)3 His-annexin A5 (His-ann A5) accumulation over time were examined. Technetium-99 122-135 annexin A5 Mus musculus 169-179 22409267-2 2012 This study evaluated the pharmacokinetic profile of a CCK-2 receptor-specific peptide, Demogastrin 1, labeled with technetium-99m ((99m)Tc-Demogastrin 1), in rats. Technetium-99 115-128 cholecystokinin B receptor Rattus norvegicus 54-68 21873267-2 2011 METHODS: Eight patients with active RA, 28-joint DAS (DAS-28) >= 3.2 and a healthy volunteer underwent whole body and hand/wrist scintigraphy after the administration of anti-human TNF-alpha labelled with technetium-99m ((99m)Tc). Technetium-99 208-221 tumor necrosis factor Homo sapiens 184-193 19430321-1 2009 AIM: To evaluate the stability of the mixture of technetium-99m (99mTc) human serum albumin (HSA) with the local anesthetic lidocaine hydrochloride. Technetium-99 49-62 albumin Homo sapiens 78-91 21666238-0 2011 Technetium-99 conjugated with methylene diphosphonate (99Tc-MDP) inhibits experimental choroidal neovascularization in vivo and VEGF-induced cell migration and tube formation in vitro. Technetium-99 0-13 vascular endothelial growth factor A Mus musculus 128-132 20538463-2 2010 In this study, we synthesized technetium-99m labeled 1,2,3-triazole-4-yl c-Met binding peptide (cMBP) derivatives, prepared by solid phase peptide synthesis and the "click-to-chelate" protocol for the introduction of tricarbonyl technetium-99m, as a potential c-Met receptor kinase positive tumor imaging agent, and evaluated their in vitro c-Met binding affinity, cellular uptake, and stability. Technetium-99 30-43 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 73-78 20538463-2 2010 In this study, we synthesized technetium-99m labeled 1,2,3-triazole-4-yl c-Met binding peptide (cMBP) derivatives, prepared by solid phase peptide synthesis and the "click-to-chelate" protocol for the introduction of tricarbonyl technetium-99m, as a potential c-Met receptor kinase positive tumor imaging agent, and evaluated their in vitro c-Met binding affinity, cellular uptake, and stability. Technetium-99 30-43 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 260-265 20538463-2 2010 In this study, we synthesized technetium-99m labeled 1,2,3-triazole-4-yl c-Met binding peptide (cMBP) derivatives, prepared by solid phase peptide synthesis and the "click-to-chelate" protocol for the introduction of tricarbonyl technetium-99m, as a potential c-Met receptor kinase positive tumor imaging agent, and evaluated their in vitro c-Met binding affinity, cellular uptake, and stability. Technetium-99 30-43 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 260-265 20538463-2 2010 In this study, we synthesized technetium-99m labeled 1,2,3-triazole-4-yl c-Met binding peptide (cMBP) derivatives, prepared by solid phase peptide synthesis and the "click-to-chelate" protocol for the introduction of tricarbonyl technetium-99m, as a potential c-Met receptor kinase positive tumor imaging agent, and evaluated their in vitro c-Met binding affinity, cellular uptake, and stability. Technetium-99 229-242 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 73-78 20346867-0 2010 Synthesis and evaluation of a technetium-99m labeled cytotoxic bombesin peptide conjugate for targeting bombesin receptor-expressing tumors. Technetium-99 30-43 gastrin releasing peptide Homo sapiens 63-71 20346867-0 2010 Synthesis and evaluation of a technetium-99m labeled cytotoxic bombesin peptide conjugate for targeting bombesin receptor-expressing tumors. Technetium-99 30-43 gastrin releasing peptide Homo sapiens 104-112 20152713-0 2010 A 1-methyl-4-piperidinyl cytectrene carboxylate labeled by the technetium 99m, a radiotracer for rat brain acetylcholinesterase activity. Technetium-99 63-76 acetylcholinesterase Rattus norvegicus 107-127 20152713-3 2010 Our aim was to study AChE activity using piperidinyl ester labelled with technetium-99m. Technetium-99 73-86 acetylcholinesterase Rattus norvegicus 21-25 20936711-0 2011 Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice. Technetium-99 60-73 epidermal growth factor receptor Mus musculus 83-115 20411168-3 2010 Scintigraphy for the detection of SLN was performed 2-4h before surgery by injecting technetium-99m labeled nanocolloid intradermally in the peritumoral region. Technetium-99 85-98 sarcolipin Homo sapiens 34-37 17540565-0 2008 WITHDRAWN: Predicting multidrug resistance-related protein and P-glycoprotein expression with technetium-99m tetrofosmin mammoscintigraphy. Technetium-99 94-107 chromosome 19 open reading frame 48 Homo sapiens 22-58 18992656-1 2008 OBJECTIVES: We examined the sodium-iodide symporter (NIS), which promotes in vivo cellular uptake of technetium 99m ((99m)Tc) or iodine 124 ((124)I), as a reporter gene for cell tracking by single-photon emission computed tomography (SPECT) or positron emission tomography (PET) imaging. Technetium-99 101-114 solute carrier family 5 member 5 Rattus norvegicus 28-51 17540565-0 2008 WITHDRAWN: Predicting multidrug resistance-related protein and P-glycoprotein expression with technetium-99m tetrofosmin mammoscintigraphy. Technetium-99 94-107 ATP binding cassette subfamily B member 1 Homo sapiens 63-77 17921030-1 2007 In the past 10 years, significant progress has been made in using a technetium-99m dopamine transporter imaging agent, [99mTc]TRODAT, for routine clinical studies. Technetium-99 68-81 solute carrier family 6 member 3 Homo sapiens 83-103 18220774-9 2008 In some preliminary publications, several authors reported on the in vivo use of caspase-inhibitors and annexin V, labeled with indium-111, technetium-99m, iodine-123, iodine-124 or fluoride-18. Technetium-99 140-153 annexin A5 Homo sapiens 104-113 16546682-3 2006 The present study reports a method to construct a chimera of phosphorodiamidate morpholino nucleobase oligomer (MORF) covalently conjugated to a peptide containing a cell membrane transduction Tat peptide and an N(2)S(2) chelator for technetium-99m ((99m)Tc) radiolabeling (N(2)S(2)-Tat-MORF). Technetium-99 234-247 lysine acetyltransferase 6B Homo sapiens 112-116 17409678-0 2007 On-site preparation of technetium-99m labeled human serum albumin for clinical application. Technetium-99 23-36 albumin Homo sapiens 52-65 17409678-1 2007 Technetium-99m labeled human serum albumin (Tc-99m HSA) is an important radiopharmaceutical for clinical applications, such as cardiac function tests or protein-losing gastroenteropathy assessment. Technetium-99 0-13 albumin Homo sapiens 29-42 17892130-0 2007 [Technetium-99m labeled synaptotagmin I C2A detection of paclitaxel-induced apoptosis in non-small cell lung cancer]. Technetium-99 1-14 synaptotagmin I Mus musculus 24-39 17111160-5 2007 Expression of caveolin-1 at the protein level in renal tissue and urine was demonstrated in patients with technetium 99 m labeled diethylene triamine pentaacetate ((99)Tc DTPA) renal scan 28.8+/-2% and increased tubular interstitial fibrosis in seven patients at the time of obstruction release. Technetium-99 106-119 caveolin 1 Homo sapiens 14-24 17257073-1 2006 UNLABELLED: In addition to tumor size, it has been suggested that P-glycoprotein (P-gp) expression and/or oxyphilic cell content in parathyroid adenomas has an important influence on the results of technetium 99m methoxyisobutylisonitrile (Tc-99m MIBI) parathyroid imaging. Technetium-99 198-211 ATP binding cassette subfamily B member 1 Homo sapiens 66-80 17257073-1 2006 UNLABELLED: In addition to tumor size, it has been suggested that P-glycoprotein (P-gp) expression and/or oxyphilic cell content in parathyroid adenomas has an important influence on the results of technetium 99m methoxyisobutylisonitrile (Tc-99m MIBI) parathyroid imaging. Technetium-99 198-211 ATP binding cassette subfamily B member 1 Homo sapiens 82-86 16546682-3 2006 The present study reports a method to construct a chimera of phosphorodiamidate morpholino nucleobase oligomer (MORF) covalently conjugated to a peptide containing a cell membrane transduction Tat peptide and an N(2)S(2) chelator for technetium-99m ((99m)Tc) radiolabeling (N(2)S(2)-Tat-MORF). Technetium-99 234-247 tyrosine aminotransferase Homo sapiens 193-196 15081753-0 2004 Accumulation of technetium-99 in the Irish Sea? Technetium-99 16-29 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 43-46 16617402-2 2006 The findings in this case were compared with the intravenously injected methylene disphosphonate technetium-99m ((99m)Tc-MDP) scintigraphic findings and could be interpreted as the result of (99m)Tc-pertechenate through blood communication from the right to the left knee. Technetium-99 97-110 dipeptidase 1 Homo sapiens 121-124 17406220-3 2006 Here we describe the most used method for labeling annexin V, a protein with a high affinity for apoptotic cells in vitro, with technetium-99m (99mTc) as a radionuclide imaging agent that can localize and non-invasively quantify apoptosis in vivo when coupled with single-photon emission tomography. Technetium-99 128-141 annexin A5 Homo sapiens 51-60 16097634-4 2005 Anti-IL-6-receptor antibodies were conjugated with a bifunctional chelating agent, hydrazinonicotinamide (HYNIC), and radiolabeled with technetium-99m (99mTc) using the ligand exchange reaction of 99mTc-tricine complex. Technetium-99 136-149 interleukin 6 Homo sapiens 5-9 14676140-4 2003 Animals were injected with human recombinant annexin V labeled with technetium-99m before imaging. Technetium-99 68-81 annexin A5 Homo sapiens 45-54 15068617-0 2004 In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging. Technetium-99 56-69 cholecystokinin B receptor Mus musculus 101-115 14514974-1 2003 The purpose of this study was to predict chemotherapy response by technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) lung single-photon-emission computed tomography (SPECT) and compare P-glycoprotein (Pgp) expression in patients with untreated small cell lung cancer (SCLC). Technetium-99 66-79 ATP binding cassette subfamily B member 1 Homo sapiens 205-208 14521888-1 2003 AIM: The aim of this study was to evaluate the effectiveness of technetium-99m tetrofosmin (Tc-99m TF) single photon emission computed tomography (SPECT) of the neck and chest to detect metastatic lesions in papillary thyroid carcinoma (PTC) after near total thyroidectomy and radioiodine (I-131) treatment in patients who present with elevated serum human thyroglobulin (hTg) levels but negative I-131 whole body scan (WBS). Technetium-99 64-77 thyroglobulin Homo sapiens 357-370 12960470-3 2003 A boost in the research in this direction has been provided by noninvasive means of detection of apoptosis, such as that achieved by technetium-99m labeled Annexin-A5 scintigraphy. Technetium-99 133-146 annexin A5 Homo sapiens 156-166 12657370-7 2003 Technetium-99m (99mTc)-radiolabeling of the annexin V and superparamagnetic iron oxide (SPIO) labeling of the C2 domain of synaptotagmin I allow good in vivo apoptosis detection by gamma camera imaging and MRI, respectively. Technetium-99 0-13 annexin A5 Homo sapiens 44-53 12915065-0 2003 Sea-to-land transfer of technetium-99 through the use of contaminated seaweed as an agricultural soil conditioner. Technetium-99 24-37 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 12438528-5 2002 In this study, we show that the CRH-receptor antagonist Antalarmin blocks stress-induced 99Tc extravasation, whereas site-specific injection of CRH in the paraventricular nucleus (PVN) of the hypothalamus mimics acute stress. Technetium-99 89-93 corticotropin releasing hormone Rattus norvegicus 32-35