PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 28427103-10 2017 Kaempferol-3-O-sophoroside (10-50 microM), but not saffron flower acetone extract, inhibited TNF-alpha-induced IL-8 secretion. kaempferol 3-O-sophoroside 0-26 tumor necrosis factor Homo sapiens 93-102 28427103-10 2017 Kaempferol-3-O-sophoroside (10-50 microM), but not saffron flower acetone extract, inhibited TNF-alpha-induced IL-8 secretion. kaempferol 3-O-sophoroside 0-26 C-X-C motif chemokine ligand 8 Homo sapiens 111-115 22178603-0 2012 Inhibitory effects of kaempferol-3-O-sophoroside on HMGB1-mediated proinflammatory responses. kaempferol 3-O-sophoroside 22-48 high mobility group box 1 Homo sapiens 52-57 22113342-7 2012 CONCLUSION: Collectively, these results suggest that KPOS possesses barrier integrity activity, inhibitory activity on cell adhesion and migration to endothelial cells by blocking the activation of NF-kappaB expression and production of TNF-alpha, thereby endorsing its usefulness as therapy for vascular inflammatory diseases. kaempferol 3-O-sophoroside 53-57 tumor necrosis factor Homo sapiens 237-246