PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 24309146-3 2014 Honokiol and beta-amyrin acetate, isolated from Magnolia officinalis and Acer mandshuricum, respectively, displayed strong inhibition of sEH activity, with respective IC50 values of 0.57 muM and 3.4 muM determined using the fluorescent substrate, and 1.7 muM and 6.1 muM determined using 14,15-epoxyeicosatrienoic acid. beta-amyrin acetate 13-32 epoxide hydrolase 2 Homo sapiens 137-140 29564983-4 2018 METHODS: Terpenoids such as abietic acid, oleanolic acid, alpha-amyrin acetate, beta-amyrin acetate were docked with AchE and HDAC3 receptors using AutoDock Vina (version 1.1.2). beta-amyrin acetate 58-78 acetylcholinesterase (Cartwright blood group) Homo sapiens 117-121 29564983-4 2018 METHODS: Terpenoids such as abietic acid, oleanolic acid, alpha-amyrin acetate, beta-amyrin acetate were docked with AchE and HDAC3 receptors using AutoDock Vina (version 1.1.2). beta-amyrin acetate 58-78 histone deacetylase 3 Homo sapiens 126-131 29564983-4 2018 METHODS: Terpenoids such as abietic acid, oleanolic acid, alpha-amyrin acetate, beta-amyrin acetate were docked with AchE and HDAC3 receptors using AutoDock Vina (version 1.1.2). beta-amyrin acetate 80-99 acetylcholinesterase (Cartwright blood group) Homo sapiens 117-121 29564983-4 2018 METHODS: Terpenoids such as abietic acid, oleanolic acid, alpha-amyrin acetate, beta-amyrin acetate were docked with AchE and HDAC3 receptors using AutoDock Vina (version 1.1.2). beta-amyrin acetate 80-99 histone deacetylase 3 Homo sapiens 126-131 27784308-7 2016 alpha-amyrin acetate and 3-epilupeol acetate, at 70 muM, also inhibited the activity of COX-2 by 62.85 and 73.28 % respectively, while alpha-amyrin and 3-epilupeol were the best inhibitors of the production of NO in LPS-activated RAW 264.7 cells with IC50 values of 15.5 and 8.98 muM respectively, and did not affected its viability. beta-amyrin acetate 0-20 cytochrome c oxidase II, mitochondrial Mus musculus 88-93 24309146-4 2014 mEH activity was decreased to 49% or 61% of control activity by 25 muM honokiol or beta-amyrin acetate, respectively. beta-amyrin acetate 83-102 epoxide hydrolase 1, microsomal Mus musculus 0-3 24309146-5 2014 These results suggest that beta-amyrin acetate and honokiol exhibit sEH inhibitory activity, although their sEH selectivity should be improved. beta-amyrin acetate 27-46 epoxide hydrolase 2 Homo sapiens 68-71 1335599-1 1992 Triterpenes--alpha-amyrin acetate, beta-amyrin acetate and beta-amyrin were tested for their effects on the synthesis of 5-lipoxygenase products in human neutrophils. beta-amyrin acetate 35-54 arachidonate 5-lipoxygenase Homo sapiens 121-135 21121258-7 2010 Among the four compounds 1-4, isolated from the methanol extract, alpha-amyrin acetate (1) and luteolin (4) showed a significant hepatoprotective activity, as indicated by their ability to prevent liver cell death and lactate dehydrogenase (LDH) leakage during CCl4 intoxication. beta-amyrin acetate 66-86 C-C motif chemokine ligand 4 Rattus norvegicus 261-265