PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 9862448-5 1998 There was a reciprocal relationship between [3H]ceramide and [3H]1,2-DAG levels with highest [3H]ceramide and lowest [3H]-1,2-DAG levels seen at lowest [Mg2+]o. 1,2-dag 65-72 mucin 7, secreted Homo sapiens 153-156 1327926-1 1992 We evaluated whether insulin-receptor tyrosine kinase activity is required for activation of PDH, insulin-induced hydrolysis of PIG and generation of IG and 1,2-DAG. 1,2-dag 157-164 insulin Cricetulus griseus 21-28 1652269-2 1991 ADH also increased the prostaglandin E (PGE) secretion into serosal medium 3.5-fold and the release of arachidonic acid (AA) from 1,2-DAG, which was intensified in the presence of DAG kinase inhibitor R59022. 1,2-dag 130-137 arginine vasopressin Homo sapiens 0-3 1652269-4 1991 It also inhibited the ADH-stimulated PGE production (55%) and release of AA from 1,2-DAG. 1,2-dag 81-88 arginine vasopressin Homo sapiens 22-25 1652269-5 1991 This data suggest that PIP2 breakdown is involved in the mechanism of feedback regulation of ADH action and is associated with PGE production via (i) the increase of AA release from PIP2-generated 1,2-DAG and (ii) possible activation of phospholipase A2 by IP3-induced elevation of cytosol Ca2+. 1,2-dag 197-204 arginine vasopressin Homo sapiens 93-96 21369919-5 2011 To elucidate the selectivity of human intestinal DGAT to 1,2-DAG or 1,3-DAG, we conducted acyl-coenzyme A:monoacylglycerol acyltransferase assays using 1- or 2-monoacylglycerol (MAG) as substrates. 1,2-dag 57-64 diacylglycerol O-acyltransferase 1 Homo sapiens 49-53 21369919-7 2011 These findings suggest that human small intestinal DGAT, which is mainly encoded by DGAT1, utilizes 1,2-DAG as the substrate to form TAG. 1,2-dag 100-107 diacylglycerol O-acyltransferase 1 Homo sapiens 51-55 21369919-7 2011 These findings suggest that human small intestinal DGAT, which is mainly encoded by DGAT1, utilizes 1,2-DAG as the substrate to form TAG. 1,2-dag 100-107 diacylglycerol O-acyltransferase 1 Homo sapiens 84-89