PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
35040431-9	2022	Before and after naps, PVT metrics were minimally different for controls, while PVT performance generally worsened following naps in the CDH group, with significant worsening compared to controls for nap 2 mean, median, lapses, and fastest 10% of responses, and nap 4 lapses and slowest 10% of responses.	cdh	137-140	napsin B aspartic peptidase, pseudogene	Homo sapiens	200-205
34259279-3	2021	The CDH coating was beneficial for osteogenic differentiation of mesenchymal stem cells (MSCs), which were reflected by the results of cellular assays, including alkaline phosphatase activity (ALP), cell mineralization capability (ARS), and osteogenesis-related gene expression.	cdh	4-7	alkaline phosphatase, placental	Homo sapiens	193-196
34259279-3	2021	The CDH coating was beneficial for osteogenic differentiation of mesenchymal stem cells (MSCs), which were reflected by the results of cellular assays, including alkaline phosphatase activity (ALP), cell mineralization capability (ARS), and osteogenesis-related gene expression.	cdh	4-7	RIEG2	Homo sapiens	231-234
1967216-12	1990	The percentage and absolute number of T3 (CD3) and T4 (CD4) positive cells at day 14 after BMT were significantly higher in the patients who maintained CDH but NK cell reconstitution was similar in both groups, suggesting that early reconstitution with T cells may play a role in preventing recovery of recipient cells after BMT.	cdh	152-155	CD4 molecule	Homo sapiens	55-58
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	keratin 17	Equus caballus	106-111
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	C-C motif chemokine 2	Equus caballus	113-117
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	C-X-C motif chemokine ligand 8	Equus caballus	119-124
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	prostaglandin-endoperoxide synthase 2	Equus caballus	126-131
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	cytochrome c oxidase subunit II	Equus caballus	142-146
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	interleukin 6	Equus caballus	149-152
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	tumor necrosis factor	Equus caballus	154-162
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	protein S100-A8	Equus caballus	164-170
34562796-4	2021	Compared to front or hind limbs at ambient temperature, CDH resulted in significantly lower expression of KRT17, CCL2, CxCL8, PTGS2 (encoding COX2), IL6, TNFalpha, S100A8 and MMP1.	cdh	56-59	MMP-1	Equus caballus	175-179
35040431-9	2022	Before and after naps, PVT metrics were minimally different for controls, while PVT performance generally worsened following naps in the CDH group, with significant worsening compared to controls for nap 2 mean, median, lapses, and fastest 10% of responses, and nap 4 lapses and slowest 10% of responses.	cdh	137-140	suppressor of cytokine signaling 7	Homo sapiens	262-267
22532008-1	2012	UNLABELLED: Our previous results showed that beta-cyclodextrin-hemin complex (CDH) exhibited a vital protective role against cadmium-induced oxidative damage and toxicity in alfalfa seedling roots by the regulation of heme oxygenase-1 (HO-1) gene expression.	cdh	78-81	heme oxygenase 1, chloroplastic	Cucumis sativus	218-234
29072876-7	2017	Using ELISA, anti-GAPDH IgG was detected in 36% (9/25) of SDH dogs and 69.2% (9/13) of the CDH dogs compared to healthy controls (0/17) (P < 0.0005).	cdh	91-94	glyceraldehyde-3-phosphate dehydrogenase	Canis lupus familiaris	18-23
23149494-7	2013	At C4-5 level, CDH was recognized at the right side in 2 cases, at the left side in 2 cases, and at the center in 7 cases.	cdh	15-18	complement C4A (Rodgers blood group)	Homo sapiens	3-7
23149494-9	2013	At C6-7 level, CDH was found at the right side in 3 cases and at the left side in 19 cases with significantly high frequency of left-sided CDH (p < 0.025).	cdh	15-18	complement C6	Homo sapiens	3-7
23149494-10	2013	CONCLUSIONS: In this study, it was revealed that the left-sided CDH was more frequent than the right-sided CDH at C6-7 level.	cdh	64-67	complement C6	Homo sapiens	114-118
23149494-10	2013	CONCLUSIONS: In this study, it was revealed that the left-sided CDH was more frequent than the right-sided CDH at C6-7 level.	cdh	107-110	complement C6	Homo sapiens	114-118
22532008-9	2012	KEY MESSAGE: Physiological, pharmacological and molecular evidence showed that beta-cyclodextrin-hemin complex (CDH) was able to induce cucumber adventitious rooting through heme oxygenase-1 (HO-1)-dependent mechanism and calcium signaling.	cdh	112-115	heme oxygenase 1, chloroplastic	Cucumis sativus	174-190
22532008-9	2012	KEY MESSAGE: Physiological, pharmacological and molecular evidence showed that beta-cyclodextrin-hemin complex (CDH) was able to induce cucumber adventitious rooting through heme oxygenase-1 (HO-1)-dependent mechanism and calcium signaling.	cdh	112-115	heme oxygenase 1, chloroplastic	Cucumis sativus	192-196
22532008-1	2012	UNLABELLED: Our previous results showed that beta-cyclodextrin-hemin complex (CDH) exhibited a vital protective role against cadmium-induced oxidative damage and toxicity in alfalfa seedling roots by the regulation of heme oxygenase-1 (HO-1) gene expression.	cdh	78-81	heme oxygenase 1, chloroplastic	Cucumis sativus	236-240
22532008-3	2012	The application of CDH and an inducer of HO-1, hemin, were able to induce the up-regulation of cucumber HO-1 gene (CsHO1) expression and thereafter the promotion of adventitious rooting in cucumber explants.	cdh	19-22	heme oxygenase 1, chloroplastic	Cucumis sativus	104-108
22532008-3	2012	The application of CDH and an inducer of HO-1, hemin, were able to induce the up-regulation of cucumber HO-1 gene (CsHO1) expression and thereafter the promotion of adventitious rooting in cucumber explants.	cdh	19-22	heme oxygenase 1, chloroplastic	Cucumis sativus	115-120
22532008-4	2012	The effect is specific for HO-1 since the potent HO-1 inhibitor zinc protoporphyrin IX (ZnPP) blocked the above responses triggered by CDH, and the inhibitory effects were reversed further when 30% saturation of CO aqueous solution was added together.	cdh	135-138	heme oxygenase 1, chloroplastic	Cucumis sativus	27-31
22532008-4	2012	The effect is specific for HO-1 since the potent HO-1 inhibitor zinc protoporphyrin IX (ZnPP) blocked the above responses triggered by CDH, and the inhibitory effects were reversed further when 30% saturation of CO aqueous solution was added together.	cdh	135-138	heme oxygenase 1, chloroplastic	Cucumis sativus	49-53
22532008-5	2012	Further, molecular evidence showed that CDH triggered the increases of the HO-1-mediated target genes responsible for adventitious rooting, including one DnaJ-like gene (CsDNAJ-1) and two calcium-dependent protein kinase (CDPK) genes (CsCDPK1 and CsCDPK5), and were inhibited by ZnPP and reversed by CO.	cdh	40-43	heme oxygenase 1, chloroplastic	Cucumis sativus	75-79
22532008-5	2012	Further, molecular evidence showed that CDH triggered the increases of the HO-1-mediated target genes responsible for adventitious rooting, including one DnaJ-like gene (CsDNAJ-1) and two calcium-dependent protein kinase (CDPK) genes (CsCDPK1 and CsCDPK5), and were inhibited by ZnPP and reversed by CO.	cdh	40-43	dnaJ protein homolog	Cucumis sativus	170-178
22532008-5	2012	Further, molecular evidence showed that CDH triggered the increases of the HO-1-mediated target genes responsible for adventitious rooting, including one DnaJ-like gene (CsDNAJ-1) and two calcium-dependent protein kinase (CDPK) genes (CsCDPK1 and CsCDPK5), and were inhibited by ZnPP and reversed by CO.	cdh	40-43	calcium-dependent protein kinase 3-like	Cucumis sativus	247-254
22532008-8	2012	In short, above results illustrated that the response of CDH in the induction of cucumber adventitious rooting might be through HO-1-dependent mechanism and calcium signaling.	cdh	57-60	heme oxygenase 1, chloroplastic	Cucumis sativus	128-132
22245778-5	2012	We show how CDH was used to identify a fragment which covers the kinase domain of MEK-1 and which expresses and crystallizes significantly better than designed expression constructs, and we report the crystal structure of this fragment which explains some of its superior properties.	cdh	12-15	mitogen-activated protein kinase kinase 1	Homo sapiens	82-87
21446842-5	2011	CDH(2) is demonstrated ab initio using a previously well-characterized Hsp90/Cdc37 complex.	cdh	0-3	heat shock protein 90 alpha family class A member 1	Homo sapiens	71-76
21446842-5	2011	CDH(2) is demonstrated ab initio using a previously well-characterized Hsp90/Cdc37 complex.	cdh	0-3	cell division cycle 37, HSP90 cochaperone	Homo sapiens	77-82
20633687-2	2010	Recently, a functional polymorphism (rs143383) of the 5"-untranslated region of GDF5 (Growth/Differentiation Factor 5) - previously reported to be associated with osteoarthritis - has been associated with CDH in a Chinese population.	cdh	205-208	growth differentiation factor 5	Homo sapiens	80-84
20633687-2	2010	Recently, a functional polymorphism (rs143383) of the 5"-untranslated region of GDF5 (Growth/Differentiation Factor 5) - previously reported to be associated with osteoarthritis - has been associated with CDH in a Chinese population.	cdh	205-208	growth differentiation factor 5	Homo sapiens	86-117
20633687-3	2010	The aim of our study was to determine whether GDF5, known to be involved in bone, joint and cartilage morphogenesis, is also associated with CDH in Caucasians.	cdh	141-144	growth differentiation factor 5	Homo sapiens	46-50
17008718-7	2006	As a proof of principle, we applied CDH to p85alpha, successfully identifying soluble and highly expressed constructs encapsulating all the known globular domains, and immediately suitable for downstream applications.	cdh	36-39	phosphoinositide-3-kinase regulatory subunit 1	Homo sapiens	43-51
11150450-10	2001	Also, lung tissue SP-B levels were low in CDH with or without TO or TR.	cdh	42-45	pulmonary surfactant-associated protein B	Ovis aries	18-22
11150450-11	2001	However, lung tissue SP-A levels were normal in CDH, but low in CDH with TO with or without TR.	cdh	48-51	pulmonary surfactant-associated protein A	Ovis aries	21-25
11150450-11	2001	However, lung tissue SP-A levels were normal in CDH, but low in CDH with TO with or without TR.	cdh	64-67	pulmonary surfactant-associated protein A	Ovis aries	21-25