PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
31010837-6	2019	RESULTS: RBS outperformed the leading existing signature for detecting RB1 biallelic loss across all cancer types in TCGA Pan-Cancer (AUC, 0.89 vs. 0.66).	Roussin's Black Salt	9-12	RB transcriptional corepressor 1	Homo sapiens	71-74
2426157-4	1986	Our results demonstrate a greater than 2000-fold range of TCGF synthesis dependent upon the promoter and the synthetic RBS used.	Roussin's Black Salt	119-122	interleukin 2	Homo sapiens	58-62
34016740-4	2021	Binding and neutralization of the two most frequently elicited antibody families (IGHV3-53/3-66 and IGHV1-2), which can both bind the RBS in alternate binding modes, are abrogated by K417N, E484K, or both.	Roussin's Black Salt	134-137	immunoglobulin heavy variable 1-2	Homo sapiens	100-107
29790499-2	2018	Upon exposure to NO, the cluster undergoes a complex nitrosylation reaction resulting in a mixture of iron-nitrosyl species, which spectroscopic studies have indicated are similar to well characterized low molecular weight dinitrosyl iron complex (DNIC), Roussin"s Red Ester (RRE) and Roussin"s Black Salt (RBS).	Roussin's Black Salt	307-310	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	285-305
22470835-7	2012	Within the acidified endosome, the heavily glycosylated GP(1) is cleaved to a smaller form by the low pH-dependent cellular proteases Cathepsin L and B, exposing residues in the receptor binding site (RBS).	Roussin's Black Salt	201-204	cathepsin L	Homo sapiens	134-151
28524102-8	2017	Lastly, we unveiled a possible mechanism for RBS action as the hypnotic effect of RBS was blocked by a histamine H1 receptor agonist.	Roussin's Black Salt	45-48	histamine receptor H1	Mus musculus	103-124
28524102-8	2017	Lastly, we unveiled a possible mechanism for RBS action as the hypnotic effect of RBS was blocked by a histamine H1 receptor agonist.	Roussin's Black Salt	82-85	histamine receptor H1	Mus musculus	103-124
23376179-3	2013	Our results indicated that RBS significantly suppressed the multivulva (Muv) phenotype of let-60 ras(gf) mutant that was positive correlated to arsenic concentrations in worms and also inhibited Muv phenotype of lin-15(lf) upstream of Ras/MAPK pathway, but did not affect the Muv phenotype resulting from loss-of-function mutations of lin-l(lf) downstream of Ras/MAPK pathway, which may be mechanism-based.	Roussin's Black Salt	27-30	Ras protein let-60	Caenorhabditis elegans	90-96
18191829-6	2008	Because an intermediate level of BMP4 signaling is required to induce neural plate border fates, we directly tested BMP4"s ability to induce RBs; beads soaked in either 1 or 10 ng/ml were able to induce RBs in cultured neural plate tissue.	Roussin's Black Salt	141-144	bone morphogenetic protein 4 L homeolog	Xenopus laevis	116-120
19934254-6	2010	The IRES(Nrf2) contains a highly conserved 18S rRNA binding site (RBS) that is required for internal initiation.	Roussin's Black Salt	66-69	NFE2 like bZIP transcription factor 2	Homo sapiens	9-13
19934254-7	2010	This IRES(Nrf2) also contains a hairpin structured inhibitory element (IE) located upstream of the RBS.	Roussin's Black Salt	99-102	NFE2 like bZIP transcription factor 2	Homo sapiens	10-14
18191829-6	2008	Because an intermediate level of BMP4 signaling is required to induce neural plate border fates, we directly tested BMP4"s ability to induce RBs; beads soaked in either 1 or 10 ng/ml were able to induce RBs in cultured neural plate tissue.	Roussin's Black Salt	203-206	bone morphogenetic protein 4 L homeolog	Xenopus laevis	116-120
14563589-8	2003	Absolute adjusted risk reduction comparing no prescription with prescription of both beta-blockers or ACE inhibitors/RBs was 13.3% for a relative adjusted risk reduction of 44%.	Roussin's Black Salt	117-120	angiotensin I converting enzyme	Homo sapiens	102-105
15992850-2	2005	Whether the CAEV gp135 receptor binding site(s) (RBS) in the functional surface envelope glycoprotein (Env) is protected from antibody binding, allowing the virus to resist neutralization, is not known.	Roussin's Black Salt	49-52	contactin 1	Homo sapiens	17-22
15992850-2	2005	Whether the CAEV gp135 receptor binding site(s) (RBS) in the functional surface envelope glycoprotein (Env) is protected from antibody binding, allowing the virus to resist neutralization, is not known.	Roussin's Black Salt	49-52	envelope polyprotein;trans-regulatory splicing-like protein	Caprine arthritis encephalitis virus	80-101
15992850-2	2005	Whether the CAEV gp135 receptor binding site(s) (RBS) in the functional surface envelope glycoprotein (Env) is protected from antibody binding, allowing the virus to resist neutralization, is not known.	Roussin's Black Salt	49-52	envelope polyprotein;trans-regulatory splicing-like protein	Caprine arthritis encephalitis virus	103-106
15992850-8	2005	Therefore, the CAEV gp135 RBS is protected from antibody binding by mechanisms both dependent and independent of Env oligomerization which are disrupted by the V1 deletion and the I166A mutation, respectively.	Roussin's Black Salt	26-29	contactin 1	Homo sapiens	20-25
15992850-8	2005	Therefore, the CAEV gp135 RBS is protected from antibody binding by mechanisms both dependent and independent of Env oligomerization which are disrupted by the V1 deletion and the I166A mutation, respectively.	Roussin's Black Salt	26-29	envelope polyprotein;trans-regulatory splicing-like protein	Caprine arthritis encephalitis virus	113-116
15050534-1	2004	A metal-nitrosyl complex, Roussin"s black salt (RBS), releases nitric oxide after illumination.	Roussin's Black Salt	48-51	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	26-46
8698845-2	1996	Addition of the iron-sulphur cluster nitrosyl Roussin"s black salt (RBS, heptanitrosyl-tri-mu3-thioxotetraferrate (1-)) resulted in a rapid and dose-dependent (50-250 microM) decline in the electrical resistance displayed by co-cultures of vascular endothelial cells and C6 glioma cells.	Roussin's Black Salt	46-66	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	68-71
11519254-4	2001	C1 epitope resides within the TNF receptor-binding site (RBS) and responsible for generation of competitive neutralizing mAbs that block TNF activity by direct RBS masking.	Roussin's Black Salt	57-60	tumor necrosis factor	Homo sapiens	30-33
11519254-4	2001	C1 epitope resides within the TNF receptor-binding site (RBS) and responsible for generation of competitive neutralizing mAbs that block TNF activity by direct RBS masking.	Roussin's Black Salt	57-60	tumor necrosis factor	Homo sapiens	137-140
11519254-4	2001	C1 epitope resides within the TNF receptor-binding site (RBS) and responsible for generation of competitive neutralizing mAbs that block TNF activity by direct RBS masking.	Roussin's Black Salt	160-163	tumor necrosis factor	Homo sapiens	30-33
11519254-4	2001	C1 epitope resides within the TNF receptor-binding site (RBS) and responsible for generation of competitive neutralizing mAbs that block TNF activity by direct RBS masking.	Roussin's Black Salt	160-163	tumor necrosis factor	Homo sapiens	137-140
11519254-5	2001	RBS-distal A1 epitope represents allosteric neutralizing mAbs that block TNF activity by conformational RBS changes.	Roussin's Black Salt	0-3	tumor necrosis factor	Homo sapiens	73-76
34508662-3	2021	X-ray crystallography revealed coordinated recognition by the heavy chain of non-RBS conserved sites and the light chain of RBS with a binding angle mimicking the angiotensin-converting enzyme 2 (ACE2) receptor.	Roussin's Black Salt	81-84	angiotensin converting enzyme 2	Homo sapiens	196-200
8460481-5	1993	Viral vectors using neomycin, beta-galactosidase, and luciferase reporters have been employed to show that RBS-mediated repression occurs in EC and embryonal stem, but not in other tested cell types.	Roussin's Black Salt	107-110	galactosidase beta 1	Homo sapiens	30-48
1702161-11	1991	The localization of the amino acid changes in HA1 to the region of the RBS supports the concept of serum inhibitors as receptor analogs.	Roussin's Black Salt	71-74	Rho GTPase activating protein 45	Homo sapiens	46-49
8522944-1	1996	Nitric oxide (NO), liberated from the photoactive donor Roussin"s black salt (RBS), was investigated for its ability to release tritium from [3H]dopamine-loaded rat striatal slices.	Roussin's Black Salt	78-81	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	56-76
34508662-3	2021	X-ray crystallography revealed coordinated recognition by the heavy chain of non-RBS conserved sites and the light chain of RBS with a binding angle mimicking the angiotensin-converting enzyme 2 (ACE2) receptor.	Roussin's Black Salt	124-127	angiotensin converting enzyme 2	Homo sapiens	163-194
34508662-3	2021	X-ray crystallography revealed coordinated recognition by the heavy chain of non-RBS conserved sites and the light chain of RBS with a binding angle mimicking the angiotensin-converting enzyme 2 (ACE2) receptor.	Roussin's Black Salt	124-127	angiotensin converting enzyme 2	Homo sapiens	196-200