PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
12006661-3	2002	Buffer-extractable fractions from the karyoplasm of stage IV-VI oocytes contain an 11S particle, prepared by immunoselection and sucrose gradient centrifugation, in which symplekin is associated with the subunits of the cleavage and polyadenylation specificity factor (CPSF).	5-chloroindole	83-86	symplekin scaffold protein S homeolog	Xenopus laevis	171-180
34165961-4	2021	Here, we report that 5-chloroindole, an unreactive analog of DHI, binds directly to the Nurr1 ligand binding domain with micromolar affinity and stimulates the activity of Nurr1, including the transcription of genes governing the synthesis and packaging of dopamine.	5-chloroindole	21-35	nuclear receptor subfamily 4 group A member 2	Homo sapiens	88-93
7509014-8	1994	KT-5720(8R*,9S*,11S*)-(-)-9-hydroxy-9-n-hexyloxy-8-methyl-2, 3, 9, 10-tetrahydro-8, 11-epoxy-1H, 8H, 11H-2,7b, 11a-triazadibenzo(a,g) cycloocta(c,d,e)trinden-1-one), an A-kinase inhibitor, inhibited the G-CSF-dependent proliferation.	5-chloroindole	16-19	colony stimulating factor 3 (granulocyte)	Mus musculus	203-208
34224803-3	2021	In this study, activation of SSTR5 by its special agonist L817,818 effectively ameliorated impaired intestinal barrier function in TNF-alpha-pretreated cells and mice with colitis.	5-chloroindole	58-62	somatostatin receptor 5	Mus musculus	29-34
34165961-4	2021	Here, we report that 5-chloroindole, an unreactive analog of DHI, binds directly to the Nurr1 ligand binding domain with micromolar affinity and stimulates the activity of Nurr1, including the transcription of genes governing the synthesis and packaging of dopamine.	5-chloroindole	21-35	nuclear receptor subfamily 4 group A member 2	Homo sapiens	172-177
29481617-5	2018	Co-immunoprecipitation experiments showed that Efg1 is a component of 90S pre-ribosomes, as it is associated with the 35S pre-rRNA and U3 snoRNA, but has stronger affinity for 23S pre-rRNA and its novel degradation intermediate 11S rRNA.	5-chloroindole	228-231	Efg1p	Saccharomyces cerevisiae S288C	47-51
748757-6	1978	We postulate that the 11S AChE is formed by a conversion of the 4S and that the shift in the S-value ratio of the enzyme reflects changes in membrane remodeling during neurite extension.	5-chloroindole	22-25	acetylcholinesterase	Mus musculus	26-30
33537033-14	2020	Low-dose 11S can block the relationship between PI3K and mTOR C2.	5-chloroindole	9-12	CREB regulated transcription coactivator 2	Mus musculus	57-64
33537033-16	2020	High-dose 11S upregulates 4E-BP2 through mTOR C1, aggravating intestinal inflammation.	5-chloroindole	10-13	eukaryotic translation initiation factor 4E binding protein 2	Homo sapiens	26-32
33537033-16	2020	High-dose 11S upregulates 4E-BP2 through mTOR C1, aggravating intestinal inflammation.	5-chloroindole	10-13	CREB regulated transcription coactivator 1	Mus musculus	41-48
29508995-5	2018	Examination of a range of receptor modulators, including ethanol, thymol, 5-hydroxyindole, and 5-chloroindole, which can affect the 5-HT3A receptor and ELIC, suggest that these compounds act via the transmembrane domain, except for 5-hydroxyindole, which can compete with 5-HT at the orthosteric binding site.	5-chloroindole	95-109	5-hydroxytryptamine receptor 3A	Homo sapiens	132-138
33464377-11	2021	The candidate gene analysis showed that polymorphisms in Gy1 promoters were significantly correlated with the 11S content.	5-chloroindole	110-113	glycinin G1	Glycine max	57-60
33537033-12	2020	Collectively, our results demonstrate that low-dose 11S could improve serum immune by secreting IFN-gamma.	5-chloroindole	52-55	interferon gamma	Homo sapiens	96-105
33537033-13	2020	The overexpression of IgG and IL-1beta is the reason that high-dose 11S reduces serum immune function, and supplementing SB can suppress this overexpression.	5-chloroindole	68-71	interleukin 1 alpha	Homo sapiens	30-38
22406901-0	2012	Isolation of glycinin (11S) from lipid-reduced soybean flour: effect of processing conditions on yields and purity.	5-chloroindole	23-26	LOC732636	Glycine max	13-21
27452662-1	2016	When soy glycinin (11S) is heated for a prolonged time at pH 2 (20 h at 85  C), a mixture is formed consisting of long semiflexible 11S fibrils and small peptides.	5-chloroindole	19-22	polyhomeotic homolog 2	Homo sapiens	58-62
23594147-5	2013	KEY RESULTS: Cl-indole (1-100 muM) potentiated agonist (5-HT) and particularly partial agonist [(S)-zacopride, DDP733, RR210, quipazine, dopamine, 2-methyl-5-HT, SR57227A, meta chlorophenyl biguanide] induced h5-HT3A receptor-mediated responses.	5-chloroindole	13-22	5-hydroxytryptamine receptor 3A	Homo sapiens	210-216
22406901-2	2012	The effects of processing conditions such as pH, reducing agent and storage time on yields and purity of glycinin (11S) were evaluated in the fractionation of soybean glycinin isolated from LRSF.	5-chloroindole	115-118	LOC732636	Glycine max	105-113
22406901-2	2012	The effects of processing conditions such as pH, reducing agent and storage time on yields and purity of glycinin (11S) were evaluated in the fractionation of soybean glycinin isolated from LRSF.	5-chloroindole	115-118	LOC732636	Glycine max	167-175
21638411-2	2009	Herein, under the conditions of appropriate pH and ionic strength, soy globulin 7S or 11S were coprecipitated with hydroxyapatite (HAp) or aragonite (Arag), respectively, to fabricate two organic/inorganic hybrids: 7S/HAp and 11S/Arag.	5-chloroindole	86-89	reticulon 3	Homo sapiens	131-134
16275338-0	2005	Purification and analysis of recombinant 11S activators of the 20S proteasome: Trypanosoma brucei PA26 and human PA28 alpha, PA28 beta, and PA28 gamma.	5-chloroindole	41-44	sestrin 1	Homo sapiens	98-102
16275338-0	2005	Purification and analysis of recombinant 11S activators of the 20S proteasome: Trypanosoma brucei PA26 and human PA28 alpha, PA28 beta, and PA28 gamma.	5-chloroindole	41-44	proteasome activator subunit 2	Homo sapiens	125-134
15080981-2	2004	The 5-chloroindole and 6-chlorobenzo[b]thiophene groups are optimal as the factor Xa S1 binding elements.	5-chloroindole	4-18	coagulation factor X	Homo sapiens	75-84