PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 3046674-1 1988 Intraarterial acetylcholine (Ach) and acetyl-beta-methylcholine (metacholine, Mch) excite feline high-threshold C-fiber mechanosensitive cutaneous sensory units (SU) in a different way. su 162-164 pro-melanin concentrating hormone Homo sapiens 78-81 32717254-6 2021 RESULTS: OVA-sensitized mice were desensitized and also had SU induced by OIT treatment, whereas repeated challenges with OVA caused the development of severe allergic reactions in OVA-sensitized mice. su 2-4 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 9-12 33759613-7 2021 The number of RCDs, the percentage of SDF and DFI, ASA and the level of caspase-3 were significantly decreased after DT and SU (p = .001 and p < .001). su 124-126 caspase 3 Homo sapiens 72-81 33759613-8 2021 When the DT and SU compared, there were significant changes in the number of RCD, the percentage of SDF and DFI, ASA and the level of caspase-3 (p < 0.05-0.001). su 16-18 caspase 3 Homo sapiens 134-143 32717254-7 2021 Administration of DAPT to mice during the OIT treatment period inhibited the establishment of SU to OVA, but did not affect the induction of desensitization. su 94-96 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 100-103 33082244-1 2020 OBJECTIVE: Weight loss diets may reduce serum urate (SU) by lowering insulin resistance while providing cardiometabolic benefits, something urate-lowering drugs have not shown in trials. su 53-55 insulin Homo sapiens 69-76 33382162-11 2021 The NSD and SU groups had an increased lambda and decreased Eloc compared to the HC group (p < 0.05). su 12-14 elongin C Homo sapiens 60-64 29458191-3 2018 We found that two SU peptides, residues 85-94 and residues 304-312, bound directly to the Nrp1 b1 domain with affinities of 7.4 and 17.7 muM, respectively. su 18-20 latexin Homo sapiens 137-140 30690853-6 2019 The Uox-KO mice had elevated SU levels and enhanced levels of atherosclerosis inflammatory response proteins. su 29-31 urate oxidase Mus musculus 4-7 30090038-7 2018 Results: SLCO2A1 protein expression was observed in 1 of 3 cases of CEAS (33%), all 13 cases of CD (100%), and all 9 cases of BD/SU (100%). su 129-131 solute carrier organic anion transporter family member 2A1 Homo sapiens 9-16 31784582-5 2019 Our results showed strong association of SU with rs4481233, rs9998811, rs7696092 and rs13145758 (minor allele frequency (MAF) = 25-44%; P < 3 x 10-14) of solute carrier family 2, member 9 (SLC2A9) and rs41481455, rs2231142 and rs1481012 (MAF = 29%; p < 3 x 10-9) of ATP-binding cassette protein, subfamily G, member 2 (ABCG2). su 41-43 solute carrier family 2 member 9 Homo sapiens 154-187 31784582-5 2019 Our results showed strong association of SU with rs4481233, rs9998811, rs7696092 and rs13145758 (minor allele frequency (MAF) = 25-44%; P < 3 x 10-14) of solute carrier family 2, member 9 (SLC2A9) and rs41481455, rs2231142 and rs1481012 (MAF = 29%; p < 3 x 10-9) of ATP-binding cassette protein, subfamily G, member 2 (ABCG2). su 41-43 solute carrier family 2 member 9 Homo sapiens 189-195 31784582-5 2019 Our results showed strong association of SU with rs4481233, rs9998811, rs7696092 and rs13145758 (minor allele frequency (MAF) = 25-44%; P < 3 x 10-14) of solute carrier family 2, member 9 (SLC2A9) and rs41481455, rs2231142 and rs1481012 (MAF = 29%; p < 3 x 10-9) of ATP-binding cassette protein, subfamily G, member 2 (ABCG2). su 41-43 ATP binding cassette subfamily B member 5 Homo sapiens 266-294 31784582-5 2019 Our results showed strong association of SU with rs4481233, rs9998811, rs7696092 and rs13145758 (minor allele frequency (MAF) = 25-44%; P < 3 x 10-14) of solute carrier family 2, member 9 (SLC2A9) and rs41481455, rs2231142 and rs1481012 (MAF = 29%; p < 3 x 10-9) of ATP-binding cassette protein, subfamily G, member 2 (ABCG2). su 41-43 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 319-324 30064993-6 2018 RESULTS: A total of 80.2% and 70.6% of the PC and SU patients were diagnosed with OSA, respectively, and 59.3% and 60.4% of those were treated with CPAP in PC and SU units, respectively. su 2-4 centromere protein J Homo sapiens 148-152 27020572-7 2016 Notably, a recombinant soluble version of the SU glycoprotein carrying the double amino acid replacement N418Q/N422Q at the V3 C-terminal side binds to CXCR4 with an efficiency similar to that of wild-type SU. su 46-48 C-X-C motif chemokine receptor 4 Homo sapiens 152-157 28804207-9 2017 In conclusion, when insulin is replaced with a sulfonylurea-class medication (SU) in NDM patients, serum C-peptide levels should be closely monitored and fine adjustment of SU dose is recommended. su 173-175 insulin Homo sapiens 20-27 27015954-3 2016 We hypothesized that component-resolved analysis of IgE, IgG4, IgA, IgA1, and IgA2 may identify potential biomarkers of SU in OIT subjects. su 120-122 immunoglobulin heavy constant epsilon Homo sapiens 52-55 27015954-3 2016 We hypothesized that component-resolved analysis of IgE, IgG4, IgA, IgA1, and IgA2 may identify potential biomarkers of SU in OIT subjects. su 120-122 immunoglobulin heavy variable 4-38-2-like Homo sapiens 63-66 27015954-3 2016 We hypothesized that component-resolved analysis of IgE, IgG4, IgA, IgA1, and IgA2 may identify potential biomarkers of SU in OIT subjects. su 120-122 immunoglobulin heavy constant alpha 1 Homo sapiens 68-72 27015954-15 2016 Lower pretreatment IgE-EW and IgE-OVM are also associated with SU. su 63-65 immunoglobulin heavy constant epsilon Homo sapiens 19-22 27015954-15 2016 Lower pretreatment IgE-EW and IgE-OVM are also associated with SU. su 63-65 immunoglobulin heavy constant epsilon Homo sapiens 30-33 28595806-4 2017 The solution was then mixed with concentrated SU in stoichiometric amounts corresponding to HAp (Ca/P molar ratio~1.67). su 46-48 reticulon 3 Homo sapiens 92-95 27826442-15 2016 Sperm selection with SU + ZP increased AR/A and AR/D rates in comparison with SU in fresh and frozen-thawed sperm. su 21-23 p21 (RAC1) activated kinase 3 Homo sapiens 39-43 25766689-8 2015 The CPAP compliance was (mean (95% CI) 4.94 (4.47 to 5.5) vs 5.23 (4.79 to 5.66) h, p=0.18) in PC and SU groups, respectively. su 102-104 centromere protein J Homo sapiens 4-8 25249548-7 2014 In ordinary linear regression, SU was significantly associated with triglyceride levels (beta=2.69 mmol/L change in triglyceride per mmol/L increase in SU). su 31-33 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 89-95 23785214-0 2013 Human T lymphotropic virus type 1 SU residue 195 plays a role in determining the preferential CD4+ T cell immortalization/transformation tropism. su 34-36 CD4 molecule Homo sapiens 94-97 24996275-12 2014 The SCS measured at d 20, 160, and 300 was genetically positively correlated with SU over the whole trajectory of 365 d, indicating a common genetic background for claw and udder health. su 82-84 SCS Bos taurus 4-7 24476385-13 2014 The results suggest that ABCG2 interacts with extra-renal metabolic pathways in a complex manner to regulate SU and gout risk. su 109-111 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 25-30 18596086-4 2008 The findings established that SU binding to CXCR4 specifically requires the V3 region of SU. su 30-32 C-X-C motif chemokine receptor 4 Homo sapiens 44-49 19578131-5 2010 The percentage of active caspase-3 and -7 decreased after SU (68.8 +/- 4.6 vs 54.2 +/- 6.0), whereas a small but significant increase of chromatin structural abnormalities was observed (DNA fragmentation index [DFI], 287.3 +/- 3.1 vs 297.2 +/- 2.4). su 58-60 caspase 3 Homo sapiens 25-41 18800055-2 2008 We have arrested Env activation at a stage prior to isomerization by alkylating the active thiol in SU and compared the structure of isomerization-arrested Env with that of native Env. su 100-102 melanoma antigen Mus musculus 17-20 22579623-3 2012 Fab15 binds an epitope that overlaps the C-terminal dsRNA binding site and, in biochemical assays, blocks the interaction of TLR3ecd with dsRNA, thus directly antagonizing TLR3 signaling through inhibition of SU formation. su 209-211 toll like receptor 3 Homo sapiens 125-129 22579623-3 2012 Fab15 binds an epitope that overlaps the C-terminal dsRNA binding site and, in biochemical assays, blocks the interaction of TLR3ecd with dsRNA, thus directly antagonizing TLR3 signaling through inhibition of SU formation. su 209-211 toll like receptor 3 Homo sapiens 172-176 22210575-8 2012 Insulin secretion capacity was impaired in three patients compared with adult control subjects but was restored after a 4-week SU trial in two patients. su 127-129 insulin Homo sapiens 0-7 22210575-9 2012 Cohort screening revealed four SU-treated patients with ABCC8 mutations, two of which are likely causal. su 31-33 ATP binding cassette subfamily C member 8 Homo sapiens 56-61 18596086-4 2008 The findings established that SU binding to CXCR4 specifically requires the V3 region of SU. su 89-91 C-X-C motif chemokine receptor 4 Homo sapiens 44-49 18596086-6 2008 Both the SU V3-specific antibodies and the full-length V3 peptide potently blocked binding of SU to CXCR4 and virus entry. su 9-11 C-X-C motif chemokine receptor 4 Homo sapiens 100-105 17945326-4 2008 Furthermore, our results suggest that residues located in the C2 disulfide-bonded loop in FeLV-C Cdom are critical for SU binding to FLVCR1 and for virus infection. su 119-121 FLVCR heme transporter 1 Homo sapiens 133-139 17016800-12 2007 CONCLUSIONS: The symptoms of SU were associated with the increased expression of TRPV1 mRNA in the trigonal mucosa. su 29-31 transient receptor potential cation channel subfamily V member 1 Homo sapiens 81-86 16488899-7 2006 A significant linear inverse relationship was observed in the SU group between SHBG and HCY (r = -0.828, p<0.01), indicating a possible influence of the sex hormones in determining HCY levels. su 62-64 sex hormone binding globulin Homo sapiens 79-83 12672711-7 2003 Only in the supplemented group (Su) with TT, did plasma glutathione peroxidase (GSH-Px) activity decrease (p < 0.05) and CD4(+) cell concentration increase (p < 0.05). su 32-34 glutathione peroxidase 3 Homo sapiens 49-78 16732727-1 2006 Soluble siglecs-1, -4, -5, -6, -7, -8, -9, and -10 were probed with polyacrylamide glycoconjugates in which: 1) the Neu5Ac residue was substituted by a sulfate group (Su); 2) glycoconjugates contained both Su and Neu5Ac; 3) sialoglycoconjugates contained a tyrosine-O-sulfate residue. su 167-169 sialic acid binding Ig like lectin 1 Homo sapiens 8-50 16041409-7 2005 Increased SU did not correlate with arterial scavenger receptor class B type I levels but paralleled increased lipoprotein lipase (LPL) levels and LPL distribution in the arterial wall. su 10-12 lipoprotein lipase Mus musculus 111-129 16041409-7 2005 Increased SU did not correlate with arterial scavenger receptor class B type I levels but paralleled increased lipoprotein lipase (LPL) levels and LPL distribution in the arterial wall. su 10-12 lipoprotein lipase Mus musculus 131-134 16041409-7 2005 Increased SU did not correlate with arterial scavenger receptor class B type I levels but paralleled increased lipoprotein lipase (LPL) levels and LPL distribution in the arterial wall. su 10-12 lipoprotein lipase Mus musculus 147-150 15763115-9 2005 The COMP alpha t values ranged from 0.5-3.6% (PT) to 0.2-1.7% (SU) for SRB bulls and from 0.4-1.8% (PT) to 0.2-1.5% (SU) for EHF bulls. su 63-65 chaperonin containing TCP1 subunit 4 Homo sapiens 71-74 12578752-16 2003 Sensitivity and specificity of SU related to BOP (BI > 0) was 29.3 % and 96.8 %, respectively. su 31-33 BOP Homo sapiens 45-48 12620804-2 2003 Vaccination of Saanen goats with pUC-based plasmid DNA expressing CAEV env induces T helper type 1 (Th1) biased immune responses to vector-encoded surface envelope (SU), and the plasmid-primed Th1 response is expanded following boost with purified SU in Freund"s incomplete adjuvant (SU-FIA) (J. C. Beyer et al., 2001, Vaccine 19, 1643-1651). su 165-167 envelope polyprotein;trans-regulatory splicing-like protein Caprine arthritis encephalitis virus 71-74 12568978-12 2002 SU was significantly correlated with PD in gingivitis, PD and CAL in periodontitis and the bleeding index in the analysis of all data. su 0-2 filamin binding LIM protein 1 Homo sapiens 62-65 11900835-7 2002 HV1 was located in a region of SU strictly conserved in all small ruminant lentivirus strains except CAEV-63. su 31-33 hydrogen voltage gated channel 1 Homo sapiens 0-3 12368329-3 2002 Each of 23 different single amino acid variants found in cDNA clones of env transcripts present after short-term culture of peripheral blood mononuclear cells from BLV-infected sheep was expressed in COS-1 cells and tested for the ability to mediate cell fusion and to be cleaved to surface (SU) and transmembrane (TM) protein subunits. su 292-294 endogenous retrovirus group W member 1, envelope Homo sapiens 72-75 12069577-4 2002 An ACAT inhibitor, Dup128, abolished FFA effects on SU, indicating that increased SU by FFA was secondary to changes in cell-free cholesterol (FC). su 52-54 acetyl-Coenzyme A acetyltransferase 1 Mus musculus 3-7 12069577-4 2002 An ACAT inhibitor, Dup128, abolished FFA effects on SU, indicating that increased SU by FFA was secondary to changes in cell-free cholesterol (FC). su 82-84 acetyl-Coenzyme A acetyltransferase 1 Mus musculus 3-7 12069577-5 2002 Consistent with these observations, ACAT inhibition increased cell FC and reduced LDL SU by half. su 86-88 acetyl-Coenzyme A acetyltransferase 1 Mus musculus 36-40 12069577-6 2002 The important role of plasma membrane composition was further demonstrated in that beta-cyclodextrin- (beta-CD-) mediated FC removal from the plasma membrane increased SU from LDL and was further stimulated by U18666A, a compound that inhibits FC transport between lysosomes and the plasma membrane. su 168-170 beta-carotene oxygenase 1 Mus musculus 83-101 12069577-6 2002 The important role of plasma membrane composition was further demonstrated in that beta-cyclodextrin- (beta-CD-) mediated FC removal from the plasma membrane increased SU from LDL and was further stimulated by U18666A, a compound that inhibits FC transport between lysosomes and the plasma membrane. su 168-170 beta-carotene oxygenase 1 Mus musculus 103-111 12069577-7 2002 In contrast, cholesterol-saturated beta-CD markedly reduced LDL SU. su 64-66 beta-carotene oxygenase 1 Mus musculus 35-42 12069577-9 2002 Moreover, HDL SU was inhibited by antimouse SR-BI antibody by more than 50% but had little effect on LDL SU. su 14-16 scavenger receptor class B, member 1 Mus musculus 44-49 12069577-11 2002 Taken together, these data suggest that LDL SU is mediated by pathways independent of SR-BI and is influenced by plasma membrane FC content. su 44-46 scavenger receptor class B, member 1 Mus musculus 86-91 12031367-10 2002 The lymphocytic infiltrate in SU is similar to that seen in IC but with fewer CD20+ cells. su 30-32 keratin 20 Homo sapiens 78-82 11641342-10 2001 These data demonstrate that SU increases the capacity for glucose release in both PP and PV hepatocytes, in part because of reciprocal changes in glucose-6-phosphatase and glucokinase. su 28-30 glucokinase Rattus norvegicus 172-183 11641342-10 2001 These data demonstrate that SU increases the capacity for glucose release in both PP and PV hepatocytes, in part because of reciprocal changes in glucose-6-phosphatase and glucokinase. su 28-30 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 146-167 11888014-7 2002 In end-of-shift samples there was a significant correlation between concentrations of Su and Sb and the metabolites PGA, MA (r = 0.714 and 0.788, p < 0.001 for Su and r = 0.644 and 0.566, p < 0.005 for Sb). su 86-88 homocysteine inducible ER protein with ubiquitin like domain 1 Homo sapiens 19-20 11888014-7 2002 In end-of-shift samples there was a significant correlation between concentrations of Su and Sb and the metabolites PGA, MA (r = 0.714 and 0.788, p < 0.001 for Su and r = 0.644 and 0.566, p < 0.005 for Sb). su 86-88 homocysteine inducible ER protein with ubiquitin like domain 1 Homo sapiens 146-147 11888014-8 2002 A high correlation between Sb and Su (r = 0.732, p < 0.001) also existed. su 34-36 homocysteine inducible ER protein with ubiquitin like domain 1 Homo sapiens 49-50 11888014-10 2002 There was a better correlation between the biological parameters at the end of the shift and the environmental styrene (r = 0.841 for PGA, r = 0.834 for MA, r = 0.788 for Su, and r = 0.698 for Sb; p < 0.001) compared with those at the start of the shift (r = 0.81 for PGA, 0.675 for MA, and 0.650 for Su; p < 0.001). su 171-173 homocysteine inducible ER protein with ubiquitin like domain 1 Homo sapiens 54-55 11287351-11 2001 It appears that SU feeding produces changes in GNG via alterations in at least two critical enzymes, G-6-Pase and PEPCK. su 16-18 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 101-109 11448844-13 2001 The results of this study suggest that the increased gluconeogenic flux observed with HF and SU diets is associated with an increased pyruvate flux through pyruvate carboxylase and PEPCK. su 93-95 pyruvate carboxylase Rattus norvegicus 156-176 11448844-13 2001 The results of this study suggest that the increased gluconeogenic flux observed with HF and SU diets is associated with an increased pyruvate flux through pyruvate carboxylase and PEPCK. su 93-95 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus 181-186 11287351-11 2001 It appears that SU feeding produces changes in GNG via alterations in at least two critical enzymes, G-6-Pase and PEPCK. su 16-18 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus 114-119 11160703-3 2001 Here we found that the seven-amino-acid sequence of the gp120 strand beta 25 in the C5 region, which is also part of the inner proximal domain, was conserved in the SU of all lentiviruses in similar or identical positions relative to the carboxy terminus of SU. su 165-167 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 56-61 11160703-3 2001 Here we found that the seven-amino-acid sequence of the gp120 strand beta 25 in the C5 region, which is also part of the inner proximal domain, was conserved in the SU of all lentiviruses in similar or identical positions relative to the carboxy terminus of SU. su 258-260 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 56-61 10438835-8 1999 Thus SDF-1, but not the smaller molecule AMD3100, may interfere at multiple points with the binding of the surface unit (SU)-CD4 complex to CXCR4, a mechanism that the covalent linkage of CD4 to CXCR4 impedes. su 121-123 C-X-C motif chemokine ligand 12 Homo sapiens 5-10 11014863-2 2000 To assess the ability of HIV-1 SU gp120 to penetrate into phospholipid membranes, we carried out a study of the interactions between a recombinant SU gp120 from HIV-1/HXB2 and artificial lipid monolayers mimicking the composition of the outer leaflet of the lymphocytes and which were spread at the air-water interface. su 31-33 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 150-155 10438835-8 1999 Thus SDF-1, but not the smaller molecule AMD3100, may interfere at multiple points with the binding of the surface unit (SU)-CD4 complex to CXCR4, a mechanism that the covalent linkage of CD4 to CXCR4 impedes. su 121-123 CD4 molecule Homo sapiens 125-128 10438835-8 1999 Thus SDF-1, but not the smaller molecule AMD3100, may interfere at multiple points with the binding of the surface unit (SU)-CD4 complex to CXCR4, a mechanism that the covalent linkage of CD4 to CXCR4 impedes. su 121-123 C-X-C motif chemokine receptor 4 Homo sapiens 140-145 10438835-8 1999 Thus SDF-1, but not the smaller molecule AMD3100, may interfere at multiple points with the binding of the surface unit (SU)-CD4 complex to CXCR4, a mechanism that the covalent linkage of CD4 to CXCR4 impedes. su 121-123 CD4 molecule Homo sapiens 188-191 8544897-4 1995 The treatment of type 2 (non-insulin-dependent) diabetes mellitus with sulphonylurea derivatives (SU), which exert their insulinotropic effect by closing the K+[ATP] channels of the pancreatic beta-cell, is customary. su 98-100 insulin Homo sapiens 29-36 10085698-6 1998 The least hypoglycaemic effect was found in patients who after IIT were treated exclusively with insulin (mean daily dose 53 +/- 2 IU) while the decrease of glycaemia was most evident in patients treated with SU given as a single drug or in combination with BG or with insulin (mean daily dose 19 +/- 1 IU). su 209-211 insulin Homo sapiens 269-276 7891766-11 1995 In women in the SU group 53% of breast cancers were: carcinoma in situ (Tis) or minimal invasive carcinoma (< 0.5 cm diameter; T1a). su 16-18 podoplanin Homo sapiens 130-133 1506417-3 1992 Although the TC used are relatively insensitive to recombinant human TNF, withdrawal of TNF causes 50% to 75% reduction of SU-induced TC-death rates, suggesting that susceptibility to TNF is raised during MO/TC-interaction by the other cytokines. su 123-125 tumor necrosis factor Homo sapiens 88-91 8482683-4 1993 During maximum binding (SB2), Cab decreased to 39 +/- 7% of the SU value (P = 0.01), matching Cab in U (P = 0.16). su 64-66 neural proliferation, differentiation and control 1 Homo sapiens 30-33 1506417-3 1992 Although the TC used are relatively insensitive to recombinant human TNF, withdrawal of TNF causes 50% to 75% reduction of SU-induced TC-death rates, suggesting that susceptibility to TNF is raised during MO/TC-interaction by the other cytokines. su 123-125 tumor necrosis factor Homo sapiens 88-91 1506417-6 1992 Combined removal of TNF, IFN-alpha/beta, lI-1, and lI-6 leads to complete prevention of SU-mediated growth inhibitory and lytic effects, suggesting that besides these cytokines other signals are not involved significantly. su 88-90 tumor necrosis factor Homo sapiens 20-23 1506417-6 1992 Combined removal of TNF, IFN-alpha/beta, lI-1, and lI-6 leads to complete prevention of SU-mediated growth inhibitory and lytic effects, suggesting that besides these cytokines other signals are not involved significantly. su 88-90 interferon alpha 1 Homo sapiens 25-34 1506417-6 1992 Combined removal of TNF, IFN-alpha/beta, lI-1, and lI-6 leads to complete prevention of SU-mediated growth inhibitory and lytic effects, suggesting that besides these cytokines other signals are not involved significantly. su 88-90 transglutaminase 1 Homo sapiens 41-45 1506417-10 1992 Mouse L cells do not follow this reaction pattern: Their death is exclusively dependent on the presence of TNF in SU and they die upon SU-exposure at postconfluent as well as at subconfluent cell density. su 114-116 tumor necrosis factor Mus musculus 107-110 1316462-0 1992 Mutations within the env gene of Mason-Pfizer monkey virus: effects on protein transport and SU-TM association. su 93-95 endogenous retrovirus group W member 1, envelope Homo sapiens 21-24 34594303-1 2021 Objective: To clarify the relationship between serum urate (SU) decrease and visceral fat area (VFA) reduction in patients with gout. su 60-62 FAT atypical cadherin 1 Homo sapiens 86-89 34343702-2 2021 Residues 90-94 of SU are considered as a Nrp1 binding site, and our previous results show that an SU peptide consisting of residues 85-94 can bind directly to the Nrp1 b1 domain with a binding affinity of 7.4 muM. su 18-20 neuropilin 1 Homo sapiens 41-45 34343702-3 2021 Therefore, the SU peptide is expected to be a good model to investigate the SU-Nrp1 interaction. su 76-78 neuropilin 1 Homo sapiens 79-83 34204277-6 2021 RESULTS: Interaction with the major reabsorptive urate transporter URAT1 appears to be dominant over interactions with secretory transporters in determining the net effect of a drug on SU levels. su 185-187 solute carrier family 22 member 12 Homo sapiens 67-72