PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
10983847-2	2000	The intrinsic activity of the compounds was also evaluated by measuring the inhibition of forskolin-stimulated 3"-5"-cyclic adenosine monophosphate (c-AMP) levels in isolated epididymal rat adipocytes.	3"-5"-cyclic adenosine monophosphate	111-147	cathelicidin antimicrobial peptide	Rattus norvegicus	149-154
3037622-1	1987	The effect of in vitro addition of vasoactive intestinal polypeptide (VIP) on the 3"-5"-cyclic adenosine monophosphate (cAMP) generating system in rat kidney glomeruli and cortical tubules was studied.	3"-5"-cyclic adenosine monophosphate	82-118	vasoactive intestinal peptide	Rattus norvegicus	35-68
2835024-1	1988	The effect of vasoactive intestinal polypeptide (VIP) on the 3"-5"-cyclic adenosine monophosphate (cAMP) generating system in membrane particles of rat portal vein was studied.	3"-5"-cyclic adenosine monophosphate	61-97	vasoactive intestinal peptide	Rattus norvegicus	14-47
2835024-1	1988	The effect of vasoactive intestinal polypeptide (VIP) on the 3"-5"-cyclic adenosine monophosphate (cAMP) generating system in membrane particles of rat portal vein was studied.	3"-5"-cyclic adenosine monophosphate	61-97	vasoactive intestinal peptide	Rattus norvegicus	49-52
7576703-1	1995	Chloride channel activity of cystic fibrosis transmembrane conductance regulator (CFTR) requires activation of protein kinase A (PKA) by 3"-5"-cyclic adenosine monophosphate (cAMP).	3"-5"-cyclic adenosine monophosphate	137-173	CF transmembrane conductance regulator	Homo sapiens	29-80
7576703-1	1995	Chloride channel activity of cystic fibrosis transmembrane conductance regulator (CFTR) requires activation of protein kinase A (PKA) by 3"-5"-cyclic adenosine monophosphate (cAMP).	3"-5"-cyclic adenosine monophosphate	137-173	CF transmembrane conductance regulator	Homo sapiens	82-86
3037622-1	1987	The effect of in vitro addition of vasoactive intestinal polypeptide (VIP) on the 3"-5"-cyclic adenosine monophosphate (cAMP) generating system in rat kidney glomeruli and cortical tubules was studied.	3"-5"-cyclic adenosine monophosphate	82-118	vasoactive intestinal peptide	Rattus norvegicus	70-73
26522133-0	2016	Role of 3"-5"-cyclic adenosine monophosphate on the epidermal growth factor dependent survival in mammary epithelial cells.	3"-5"-cyclic adenosine monophosphate	8-44	epidermal growth factor	Mus musculus	52-75
30841431-6	2019	This was through the phosphorylation of 3"-5"-cyclic adenosine monophosphate response element-binding protein (CREB) in beta-cells, hence activating CREB downstream anti-apoptotic genes, Bcl-2 and Bcl-xL.	3"-5"-cyclic adenosine monophosphate	40-76	cAMP responsive element binding protein 1	Mus musculus	111-115
30841431-6	2019	This was through the phosphorylation of 3"-5"-cyclic adenosine monophosphate response element-binding protein (CREB) in beta-cells, hence activating CREB downstream anti-apoptotic genes, Bcl-2 and Bcl-xL.	3"-5"-cyclic adenosine monophosphate	40-76	cAMP responsive element binding protein 1	Mus musculus	149-153
30841431-6	2019	This was through the phosphorylation of 3"-5"-cyclic adenosine monophosphate response element-binding protein (CREB) in beta-cells, hence activating CREB downstream anti-apoptotic genes, Bcl-2 and Bcl-xL.	3"-5"-cyclic adenosine monophosphate	40-76	B cell leukemia/lymphoma 2	Mus musculus	187-192
30841431-6	2019	This was through the phosphorylation of 3"-5"-cyclic adenosine monophosphate response element-binding protein (CREB) in beta-cells, hence activating CREB downstream anti-apoptotic genes, Bcl-2 and Bcl-xL.	3"-5"-cyclic adenosine monophosphate	40-76	BCL2-like 1	Mus musculus	197-203
28687606-2	2017	During beta-adrenergic stimulation, 3"-5"-cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) phosphorylates KCNQ1, producing an increase in IKs current and a shortening of the action potential.	3"-5"-cyclic adenosine monophosphate	36-72	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	128-133
26390815-1	2016	Epac (exchange protein activated by cyclic-AMP) 2 is a direct target of 3"-5"-cyclic adenosine monophosphate (cAMP) and is involved in cAMP-mediated signal transduction through activation of the Ras-like small GTPase Rap.	3"-5"-cyclic adenosine monophosphate	72-108	Rap guanine nucleotide exchange factor 3	Homo sapiens	0-4
26390815-1	2016	Epac (exchange protein activated by cyclic-AMP) 2 is a direct target of 3"-5"-cyclic adenosine monophosphate (cAMP) and is involved in cAMP-mediated signal transduction through activation of the Ras-like small GTPase Rap.	3"-5"-cyclic adenosine monophosphate	72-108	LDL receptor related protein associated protein 1	Homo sapiens	217-220
24155658-12	2013	Additionally, we found that airway administration of DCI, a combination of dexamethasone, 3"-5"-cyclic adenosine monophosphate, and isobutylmethylxanthine attenuated the air space enlargement in this particular model, at least in part through the recovery of lung VEGF expression.	3"-5"-cyclic adenosine monophosphate	90-126	vascular endothelial growth factor A	Mus musculus	264-268
26243800-1	2015	RATIONALE: Chronic elevation of 3"-5"-cyclic adenosine monophosphate (cAMP) levels has been associated with cardiac remodeling and cardiac hypertrophy.	3"-5"-cyclic adenosine monophosphate	32-68	cathelicidin antimicrobial peptide	Homo sapiens	70-74
25591042-2	2015	The release of endogenous catecholamines associated with shock or the administration of beta2-adrenergic receptor (beta2AR) agonists enhances AFC via a 3"-5"-cyclic adenosine monophosphate-dependent mechanism.	3"-5"-cyclic adenosine monophosphate	152-188	adrenoceptor beta 2	Homo sapiens	88-113
25591042-2	2015	The release of endogenous catecholamines associated with shock or the administration of beta2-adrenergic receptor (beta2AR) agonists enhances AFC via a 3"-5"-cyclic adenosine monophosphate-dependent mechanism.	3"-5"-cyclic adenosine monophosphate	152-188	adrenoceptor beta 2	Homo sapiens	115-122
25591042-11	2015	Furthermore, the inhibitory effect of TGF-beta1 on 3"-5"-cyclic adenosine monophosphate-stimulated alveolar epithelial fluid transport required the presence of IL-8/cytokine-induced neutrophil chemoattractant-1 (n = 12 in each group).	3"-5"-cyclic adenosine monophosphate	51-87	transforming growth factor beta 1	Homo sapiens	38-47
25591042-11	2015	Furthermore, the inhibitory effect of TGF-beta1 on 3"-5"-cyclic adenosine monophosphate-stimulated alveolar epithelial fluid transport required the presence of IL-8/cytokine-induced neutrophil chemoattractant-1 (n = 12 in each group).	3"-5"-cyclic adenosine monophosphate	51-87	C-X-C motif chemokine ligand 8	Homo sapiens	160-164
25591042-11	2015	Furthermore, the inhibitory effect of TGF-beta1 on 3"-5"-cyclic adenosine monophosphate-stimulated alveolar epithelial fluid transport required the presence of IL-8/cytokine-induced neutrophil chemoattractant-1 (n = 12 in each group).	3"-5"-cyclic adenosine monophosphate	51-87	C-X-C motif chemokine ligand 1	Rattus norvegicus	165-210
24769160-1	2014	G-protein coupled receptor 3 (GPR3), GPR6, and GPR12 belong to a family of constitutively active Gs-coupled receptors that activate 3"-5"-cyclic adenosine monophosphate (cAMP) and are highly expressed in the brain.	3"-5"-cyclic adenosine monophosphate	132-168	G-protein coupled receptor 3	Mus musculus	0-28
24769160-1	2014	G-protein coupled receptor 3 (GPR3), GPR6, and GPR12 belong to a family of constitutively active Gs-coupled receptors that activate 3"-5"-cyclic adenosine monophosphate (cAMP) and are highly expressed in the brain.	3"-5"-cyclic adenosine monophosphate	132-168	G-protein coupled receptor 3	Mus musculus	30-34
24769160-1	2014	G-protein coupled receptor 3 (GPR3), GPR6, and GPR12 belong to a family of constitutively active Gs-coupled receptors that activate 3"-5"-cyclic adenosine monophosphate (cAMP) and are highly expressed in the brain.	3"-5"-cyclic adenosine monophosphate	132-168	G protein-coupled receptor 6	Mus musculus	37-41
24769160-1	2014	G-protein coupled receptor 3 (GPR3), GPR6, and GPR12 belong to a family of constitutively active Gs-coupled receptors that activate 3"-5"-cyclic adenosine monophosphate (cAMP) and are highly expressed in the brain.	3"-5"-cyclic adenosine monophosphate	132-168	G-protein coupled receptor 12	Mus musculus	47-52
23725046-1	2014	AIMS: The purpose of this study was to determine whether 3"-5"-cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) and Sirtuin-1 (SIRT1) dependent mechanisms modulate ATP-binding Cassette (ABC) transport protein expression.	3"-5"-cyclic adenosine monophosphate	57-93	sirtuin 1	Mus musculus	139-144
23770096-2	2013	In this study, succinate was confirmed to activate GPR91 resulting in both 3"-5"-cyclic adenosine monophosphate (cAMP) inhibition and inositol phosphate formation in a pertussis toxin (PTX)-sensitive manner.	3"-5"-cyclic adenosine monophosphate	75-111	succinate receptor 1	Homo sapiens	51-56
23826079-1	2013	G protein-coupled receptor 3 (GPR3) is a constitutively active receptor that maintains high 3"-5"-cyclic adenosine monophosphate (cAMP) levels required for meiotic arrest in oocytes and CNS function.	3"-5"-cyclic adenosine monophosphate	92-128	G protein-coupled receptor 3	Homo sapiens	0-28
23826079-1	2013	G protein-coupled receptor 3 (GPR3) is a constitutively active receptor that maintains high 3"-5"-cyclic adenosine monophosphate (cAMP) levels required for meiotic arrest in oocytes and CNS function.	3"-5"-cyclic adenosine monophosphate	92-128	G protein-coupled receptor 3	Homo sapiens	30-34
19210747-1	2009	It has now been over 10 years since efforts to completely understand the signalling actions of cAMP (3"-5"-cyclic adenosine monophosphate) led to the discovery of exchange protein directly activated by cAMP (EPAC) proteins.	3"-5"-cyclic adenosine monophosphate	101-137	Rap guanine nucleotide exchange factor 3	Homo sapiens	208-212
21170647-2	2011	In this study, we demonstrate for the first time that the mitogenic response of human peripheral blood mononuclear cells (PBMCs) to GcMAF was associated with 3"-5"-cyclic adenosine monophosphate (cAMP) formation.	3"-5"-cyclic adenosine monophosphate	158-194	GC vitamin D binding protein	Homo sapiens	132-137
18466076-5	2008	TSHR constructs were characterized by determination of cell surface expression, 3"-5"-cyclic adenosine monophosphate (cAMP) accumulation, and constitutive cAMP activity.	3"-5"-cyclic adenosine monophosphate	80-116	thyroid stimulating hormone receptor	Homo sapiens	0-4