PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 8441384-12 1993 Nucleotide and predicted amino acid sequences were highly homologous to GABP-alpha and -beta, which is further supported by the observation that GABP-specific antibody can recognize human E4TF1. gabp 72-76 GA binding protein transcription factor subunit beta 1 Homo sapiens 188-193 30205050-0 2018 Disruption of the beta1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner. gabp 36-40 telomerase reverse transcriptase Mus musculus 92-96 1340465-2 1992 To investigate the selectivity and specificity of the GABP complex, we have isolated two new ETS family members, termed ER81 and ER71. gabp 54-58 ets variant 1 Mus musculus 120-124 30205050-3 2018 We show that genetic disruption of GABPbeta1L (beta1L), a tetramer-forming isoform of GABP that is dispensable for normal development, results in TERT silencing in a TERT promoter mutation-dependent manner. gabp 35-39 telomerase reverse transcriptase Mus musculus 146-150 30205050-3 2018 We show that genetic disruption of GABPbeta1L (beta1L), a tetramer-forming isoform of GABP that is dispensable for normal development, results in TERT silencing in a TERT promoter mutation-dependent manner. gabp 35-39 telomerase reverse transcriptase Mus musculus 166-170 24958105-6 2014 We conclude that Gabp regulates Tfb1m expression and plays an essential, nonredundant role in mitochondrial biogenesis. gabp 17-21 transcription factor B1, mitochondrial Mus musculus 32-37 29422527-0 2018 Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer. gabp 71-75 telomerase reverse transcriptase Homo sapiens 21-25 29422527-0 2018 Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer. gabp 71-75 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 67-70 26553150-6 2016 We characterize the dynamics of competitive binding between ELF1 and GABP and provide evidence for ELF1 exclusion by transcriptionally active GABP. gabp 142-146 E74 like ETS transcription factor 1 Homo sapiens 60-64 26553150-6 2016 We characterize the dynamics of competitive binding between ELF1 and GABP and provide evidence for ELF1 exclusion by transcriptionally active GABP. gabp 142-146 E74 like ETS transcription factor 1 Homo sapiens 99-103 28254634-0 2017 Competitive regulation of IPO4 transcription by ELK1 and GABP. gabp 57-61 importin 4 Homo sapiens 26-30 24076158-0 2013 Identification of the C/EBPalpha C-terminal tail residues involved in the protein interaction with GABP and their potency in myeloid differentiation of K562 cells. gabp 99-103 CCAAT enhancer binding protein alpha Homo sapiens 22-32 24501276-6 2014 GABP, of which GABPA is a component, is known to regulate the expression of genes such as THPO (thrombopoietin) and ATP5B (ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide) and is implicated in a wide variety of important cellular functions. gabp 0-4 GA binding protein transcription factor subunit alpha Homo sapiens 15-20 24501276-6 2014 GABP, of which GABPA is a component, is known to regulate the expression of genes such as THPO (thrombopoietin) and ATP5B (ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide) and is implicated in a wide variety of important cellular functions. gabp 0-4 thrombopoietin Homo sapiens 90-94 24501276-6 2014 GABP, of which GABPA is a component, is known to regulate the expression of genes such as THPO (thrombopoietin) and ATP5B (ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide) and is implicated in a wide variety of important cellular functions. gabp 0-4 thrombopoietin Homo sapiens 96-110 24501276-6 2014 GABP, of which GABPA is a component, is known to regulate the expression of genes such as THPO (thrombopoietin) and ATP5B (ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide) and is implicated in a wide variety of important cellular functions. gabp 0-4 ATP synthase F1 subunit beta Homo sapiens 116-121 24501276-6 2014 GABP, of which GABPA is a component, is known to regulate the expression of genes such as THPO (thrombopoietin) and ATP5B (ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide) and is implicated in a wide variety of important cellular functions. gabp 0-4 ATP synthase F1 subunit beta Homo sapiens 123-196 24705138-7 2014 Upon differentiation into the parietal endoderm by retinoic acid and cAMP, Lrh-1 promoter activity and transcripts were markedly reduced within 24 h. At the same time, Sox2 and Gabp binding to the promoter region of Lrh-1 were decreased, followed by a reduction of their expression. gabp 177-181 nuclear receptor subfamily 5 group A member 2 Homo sapiens 75-80 24705138-7 2014 Upon differentiation into the parietal endoderm by retinoic acid and cAMP, Lrh-1 promoter activity and transcripts were markedly reduced within 24 h. At the same time, Sox2 and Gabp binding to the promoter region of Lrh-1 were decreased, followed by a reduction of their expression. gabp 177-181 nuclear receptor subfamily 5 group A member 2 Homo sapiens 216-221 23684612-4 2013 The depletion of GABP downregulates YAP, resulting in a G1/S cell-cycle block and increased cell death, both of which are substantially rescued by reconstituting YAP. gabp 17-21 Yes1 associated transcriptional regulator Homo sapiens 36-39 23539139-5 2013 Examination of the DNA sequences underlying the HCFC1-binding sites revealed three sequence motifs associated with the binding of (1) ZNF143 and THAP11 (also known as Ronin), (2) GABP, and (3) YY1 sequence-specific transcription factors. gabp 179-183 host cell factor C1 Homo sapiens 48-53 23684612-4 2013 The depletion of GABP downregulates YAP, resulting in a G1/S cell-cycle block and increased cell death, both of which are substantially rescued by reconstituting YAP. gabp 17-21 Yes1 associated transcriptional regulator Homo sapiens 162-165 23684612-8 2013 In human liver cancers, enhanced YAP expression is correlated with increased nuclear expression of GABP. gabp 99-103 Yes1 associated transcriptional regulator Homo sapiens 33-36 23684612-9 2013 Therefore, we conclude that GABP is an activator of Yap gene expression and a potential therapeutic target for cancers driven by YAP. gabp 28-32 Yes1 associated transcriptional regulator Homo sapiens 52-55 23684612-9 2013 Therefore, we conclude that GABP is an activator of Yap gene expression and a potential therapeutic target for cancers driven by YAP. gabp 28-32 Yes1 associated transcriptional regulator Homo sapiens 129-132 21609478-11 2011 CONCLUSIONS: Both NRF-1 and GABP have been linked to the regulation of nuclear-encoded mitochondrial proteins, and the results of this study suggest their expression is coordinated by NRF-1"s activation of the GABPbeta promoter. gabp 28-32 nuclear respiratory factor 1 Homo sapiens 184-189 23516450-6 2013 Several ANNs were constructed and finally a Back Propagation network optimized by a genetic algorithm (GABP network) was chosen as a superior model, which included six input variables; i.e., serum creatinine, serum urea nitrogen, age, height, weight and gender, and estimated GFR as the one output variable. gabp 103-107 Rap guanine nucleotide exchange factor 5 Homo sapiens 276-279 22862946-2 2012 The GABP complex, consisting of DNA binding GABPalpha subunit and transactivation GABPbeta subunit, critically regulates HSC multipotency and self-renewal via controlling an essential gene regulatory module. gabp 4-8 GA binding protein transcription factor subunit alpha Homo sapiens 44-53 22862946-2 2012 The GABP complex, consisting of DNA binding GABPalpha subunit and transactivation GABPbeta subunit, critically regulates HSC multipotency and self-renewal via controlling an essential gene regulatory module. gabp 4-8 GA binding protein transcription factor subunit beta 1 Homo sapiens 82-90 22306510-0 2012 Identification of Rhit as a novel transcriptional repressor of human Mpv17-like protein with a mitigating effect on mitochondrial dysfunction, and its transcriptional regulation by FOXD3 and GABP. gabp 191-195 zinc finger protein 205 Homo sapiens 18-22 22306510-0 2012 Identification of Rhit as a novel transcriptional repressor of human Mpv17-like protein with a mitigating effect on mitochondrial dysfunction, and its transcriptional regulation by FOXD3 and GABP. gabp 191-195 MPV17 mitochondrial inner membrane protein like Homo sapiens 69-87 21705494-7 2011 Gabp bound and activated the Gfi1 promoter, and transduction of Gabpa knockout bone marrow with Gfi1 partially rescued defects in myeloid colony formation and myeloid differentiation. gabp 0-4 growth factor independent 1 transcription repressor Mus musculus 29-33 21705494-7 2011 Gabp bound and activated the Gfi1 promoter, and transduction of Gabpa knockout bone marrow with Gfi1 partially rescued defects in myeloid colony formation and myeloid differentiation. gabp 0-4 growth factor independent 1 transcription repressor Mus musculus 96-100 21705494-8 2011 We conclude that Gabp is required for myeloid differentiation due, in part, to its regulation of the tran-scriptional repressor Gfi-1. gabp 17-21 growth factor independent 1 transcription repressor Mus musculus 128-133 21609478-11 2011 CONCLUSIONS: Both NRF-1 and GABP have been linked to the regulation of nuclear-encoded mitochondrial proteins, and the results of this study suggest their expression is coordinated by NRF-1"s activation of the GABPbeta promoter. gabp 28-32 GA binding protein transcription factor subunit beta 1 Homo sapiens 210-218 18378679-5 2008 Furthermore, inactivation of the GABP-binding site by nucleotide substitutions as well as repression of GABPalpha expression by RNA interference reduced Sp1-mediated transactivation of the FcRgamma promoter, demonstrating that Sp1 and GABP synergistically activated the FcRgamma promoter. gabp 33-37 Fc epsilon receptor Ig Homo sapiens 189-197 21931859-8 2011 Expression of FLI-1, ELF-1, and GABP activated the PF4 promoter in HepG2 cells. gabp 32-36 platelet factor 4 Homo sapiens 51-54 20937353-6 2011 Co-transfection of plasmids expressing GABP-alpha and GABP-beta stimulated activity of the non-mutated PRDX5 promoter but had no effect on the mutated promoter, suggesting that basal expression of the human PRDX5 gene is regulated by GABP. gabp 39-43 peroxiredoxin 5 Homo sapiens 103-108 20937353-6 2011 Co-transfection of plasmids expressing GABP-alpha and GABP-beta stimulated activity of the non-mutated PRDX5 promoter but had no effect on the mutated promoter, suggesting that basal expression of the human PRDX5 gene is regulated by GABP. gabp 39-43 peroxiredoxin 5 Homo sapiens 207-212 19822575-2 2009 In a previous ChIP-chip study of USF1 and USF2 we found evidence also of binding of GABP, FOXA2 and HNF4a within the enriched regions. gabp 84-88 upstream transcription factor 1 Homo sapiens 33-37 19822575-2 2009 In a previous ChIP-chip study of USF1 and USF2 we found evidence also of binding of GABP, FOXA2 and HNF4a within the enriched regions. gabp 84-88 upstream transcription factor 2, c-fos interacting Homo sapiens 42-46 19822575-2 2009 In a previous ChIP-chip study of USF1 and USF2 we found evidence also of binding of GABP, FOXA2 and HNF4a within the enriched regions. gabp 84-88 hepatocyte nuclear factor 4 alpha Homo sapiens 100-105 19822575-7 2009 An interaction between HNF4a and GABP was seen at TSS, with one-third of the HNF4a positive promoters being bound also by GABP, and this interaction was verified by co-immunoprecipitations. gabp 33-37 hepatocyte nuclear factor 4 alpha Homo sapiens 23-28 19822575-7 2009 An interaction between HNF4a and GABP was seen at TSS, with one-third of the HNF4a positive promoters being bound also by GABP, and this interaction was verified by co-immunoprecipitations. gabp 33-37 hepatocyte nuclear factor 4 alpha Homo sapiens 77-82 19822575-7 2009 An interaction between HNF4a and GABP was seen at TSS, with one-third of the HNF4a positive promoters being bound also by GABP, and this interaction was verified by co-immunoprecipitations. gabp 122-126 hepatocyte nuclear factor 4 alpha Homo sapiens 23-28 19822575-7 2009 An interaction between HNF4a and GABP was seen at TSS, with one-third of the HNF4a positive promoters being bound also by GABP, and this interaction was verified by co-immunoprecipitations. gabp 122-126 hepatocyte nuclear factor 4 alpha Homo sapiens 77-82 18343819-0 2008 PGC-1-related coactivator complexes with HCF-1 and NRF-2beta in mediating NRF-2(GABP)-dependent respiratory gene expression. gabp 80-84 PPARG related coactivator 1 Homo sapiens 0-25 18343819-0 2008 PGC-1-related coactivator complexes with HCF-1 and NRF-2beta in mediating NRF-2(GABP)-dependent respiratory gene expression. gabp 80-84 NFE2 like bZIP transcription factor 2 Homo sapiens 51-56 17260004-10 2007 Therefore, HGF induced thrombopoiesis accompanied with the overexpression of TPO through GABP stimulation. gabp 89-93 hepatocyte growth factor Mus musculus 11-14 18378679-5 2008 Furthermore, inactivation of the GABP-binding site by nucleotide substitutions as well as repression of GABPalpha expression by RNA interference reduced Sp1-mediated transactivation of the FcRgamma promoter, demonstrating that Sp1 and GABP synergistically activated the FcRgamma promoter. gabp 104-108 Fc epsilon receptor Ig Homo sapiens 189-197 18378679-7 2008 On the other hand, GABP and Elf-1, whose recognition sequences overlapped, were shown to bind the FcRgamma gene with similar affinity in the context of chromatin, although Elf-1 exerted weaker enhancer activity for FcRgamma gene expression than did GABP. gabp 19-23 Fc epsilon receptor Ig Homo sapiens 98-106 18378679-7 2008 On the other hand, GABP and Elf-1, whose recognition sequences overlapped, were shown to bind the FcRgamma gene with similar affinity in the context of chromatin, although Elf-1 exerted weaker enhancer activity for FcRgamma gene expression than did GABP. gabp 19-23 Fc epsilon receptor Ig Homo sapiens 215-223 18378679-7 2008 On the other hand, GABP and Elf-1, whose recognition sequences overlapped, were shown to bind the FcRgamma gene with similar affinity in the context of chromatin, although Elf-1 exerted weaker enhancer activity for FcRgamma gene expression than did GABP. gabp 249-253 E74 like ETS transcription factor 1 Homo sapiens 28-33 18378679-7 2008 On the other hand, GABP and Elf-1, whose recognition sequences overlapped, were shown to bind the FcRgamma gene with similar affinity in the context of chromatin, although Elf-1 exerted weaker enhancer activity for FcRgamma gene expression than did GABP. gabp 249-253 Fc epsilon receptor Ig Homo sapiens 98-106 18378679-7 2008 On the other hand, GABP and Elf-1, whose recognition sequences overlapped, were shown to bind the FcRgamma gene with similar affinity in the context of chromatin, although Elf-1 exerted weaker enhancer activity for FcRgamma gene expression than did GABP. gabp 249-253 Fc epsilon receptor Ig Homo sapiens 215-223 18097041-7 2008 We further showed that pro-IL-16 is located in a GABP transcriptional complex bound to the Skp2 promoter. gabp 49-53 S-phase kinase associated protein 2 Homo sapiens 91-95 17260004-10 2007 Therefore, HGF induced thrombopoiesis accompanied with the overexpression of TPO through GABP stimulation. gabp 89-93 thrombopoietin Mus musculus 77-80 16574658-0 2006 Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1. gabp 50-54 aurora kinase A Mus musculus 14-22 16709851-9 2006 As GABP is widely expressed, a strong TATA box thus alleviates promyelocytic cell specificity of the def1 promoter. gabp 3-7 defensin alpha 1 Homo sapiens 101-105 17304221-5 2007 Here we demonstrate that upon activation, GABP recruits the histone acetyl transferase (HAT) p300 on the AChR epsilon subunit promoter, whereas it rather recruits the histone deacetylase HDAC1 when the promoter is not activated. gabp 42-46 E1A binding protein p300 Homo sapiens 93-97 17304221-5 2007 Here we demonstrate that upon activation, GABP recruits the histone acetyl transferase (HAT) p300 on the AChR epsilon subunit promoter, whereas it rather recruits the histone deacetylase HDAC1 when the promoter is not activated. gabp 42-46 histone deacetylase 1 Homo sapiens 187-192 16574658-0 2006 Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1. gabp 50-54 mediator complex subunit 1 Mus musculus 70-77 16574658-0 2006 Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1. gabp 50-54 mediator complex subunit 1 Mus musculus 78-82 16412436-0 2006 Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor. gabp 63-67 adhesion G protein-coupled receptor B2 Homo sapiens 0-39 16309857-2 2006 GABP is composed of two subunits; the GABP alpha subunit is a member of the Ets-family of transcription factors, and the unrelated ankyrin repeat containing GABP beta subunit. gabp 0-4 GA repeat binding protein, alpha Mus musculus 38-48 16309857-2 2006 GABP is composed of two subunits; the GABP alpha subunit is a member of the Ets-family of transcription factors, and the unrelated ankyrin repeat containing GABP beta subunit. gabp 0-4 GA repeat binding protein, beta 1 Mus musculus 157-166 16309857-7 2006 The core of the GAA/CF6 bidirectional promoter is retained within a 400 bp sequence and contains four GABP binding sites, a Sp1/3 binding site and an YY1 binding site. gabp 102-106 GA repeat binding protein, alpha Mus musculus 16-19 16309857-7 2006 The core of the GAA/CF6 bidirectional promoter is retained within a 400 bp sequence and contains four GABP binding sites, a Sp1/3 binding site and an YY1 binding site. gabp 102-106 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F Mus musculus 20-23 16309857-11 2006 Binding of GABP to the GAA/CF6 bi-directional promoter provides the potential for autoregulation of GABP alpha expression and confirms the importance of GABP in the coordinate expression of respiratory chain components. gabp 11-15 GA repeat binding protein, alpha Mus musculus 23-26 16309857-11 2006 Binding of GABP to the GAA/CF6 bi-directional promoter provides the potential for autoregulation of GABP alpha expression and confirms the importance of GABP in the coordinate expression of respiratory chain components. gabp 11-15 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F Mus musculus 27-30 16309857-11 2006 Binding of GABP to the GAA/CF6 bi-directional promoter provides the potential for autoregulation of GABP alpha expression and confirms the importance of GABP in the coordinate expression of respiratory chain components. gabp 11-15 GA repeat binding protein, alpha Mus musculus 100-110 16309857-11 2006 Binding of GABP to the GAA/CF6 bi-directional promoter provides the potential for autoregulation of GABP alpha expression and confirms the importance of GABP in the coordinate expression of respiratory chain components. gabp 100-104 GA repeat binding protein, alpha Mus musculus 23-26 16309857-11 2006 Binding of GABP to the GAA/CF6 bi-directional promoter provides the potential for autoregulation of GABP alpha expression and confirms the importance of GABP in the coordinate expression of respiratory chain components. gabp 100-104 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F Mus musculus 27-30 16412436-0 2006 Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor. gabp 63-67 vascular endothelial growth factor A Homo sapiens 50-54 12463423-14 2002 Furthermore, our experiments demonstrate that occupation of the GABP binding site results in a substantial decrease in S3a promoter activity. gabp 64-68 ribosomal protein S3A Homo sapiens 119-122 15966902-7 2005 On the other hand, upon induction of differentiation, the GABP cofactor HCF-1 is recruited to and coactivates the promoter with GABP. gabp 58-62 host cell factor C1 Homo sapiens 72-77 15966902-7 2005 On the other hand, upon induction of differentiation, the GABP cofactor HCF-1 is recruited to and coactivates the promoter with GABP. gabp 128-132 host cell factor C1 Homo sapiens 72-77 15147836-3 2004 Previous studies have demonstrated that NRG-1-induced transcription is conferred by cis-acting elements located within 100 bp of 5" flanking DNA from the AChR epsilon subunit gene, and that it requires a GABP binding site within this region. gabp 204-208 neuregulin 1 Homo sapiens 40-45 16412436-6 2006 Our results point out that BAI2 controls VEGF transcription through GABP under normal conditions and cerebral ischemia. gabp 68-72 adhesion G protein-coupled receptor B2 Homo sapiens 27-31 16412436-6 2006 Our results point out that BAI2 controls VEGF transcription through GABP under normal conditions and cerebral ischemia. gabp 68-72 vascular endothelial growth factor A Homo sapiens 41-45 15928042-0 2005 C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter. gabp 54-58 CCAAT enhancer binding protein alpha Homo sapiens 0-10 15928042-0 2005 C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter. gabp 54-58 CD79a molecule Homo sapiens 89-92 15928042-0 2005 C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter. gabp 54-58 Fc alpha receptor Homo sapiens 106-115 15928042-0 2005 C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter. gabp 54-58 Fc alpha receptor Homo sapiens 117-121 15928042-5 2005 GABP and C/EBPalpha synergistically activated the FCAR promoter 280-fold. gabp 0-4 Fc alpha receptor Homo sapiens 50-54 15928042-7 2005 This is the first report demonstrating both physical and functional interactions between GABP and C/EBPalpha and will provide new insights into the molecular basis of myeloid gene expression. gabp 89-93 CCAAT enhancer binding protein alpha Homo sapiens 98-108 14743390-6 2004 Time courses showed differential activation patterns of transcription factors with early induction of FUSE binding protein 1 (FBP) and c-Jun, and later steady upregulation of NFATc1 and GABP by RANKL. gabp 186-190 TNF superfamily member 11 Homo sapiens 194-199 11237613-0 2001 Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter. gabp 52-56 Ser7 Drosophila melanogaster 8-11 11318655-0 2001 Neuregulin-1-stimulated phosphorylation of GABP in skeletal muscle cells. gabp 43-47 neuregulin 1 Mus musculus 0-12 11318655-6 2001 To determine whether MAP kinases might directly regulate the activity of GABP, we studied MAP kinase-catalyzed and NRG-1-induced phosphorylation of GABPalpha and GABPbeta. gabp 73-77 neuregulin 1 Mus musculus 115-120 11237613-5 2001 Co-transfections of the promoter with Sp1, Sp3 and GABP factors in Drosophila SL2 Schneider cells, which lack of endogenous Sp factors, demonstrated that both Sp1 and Sp3 are positive regulators of the utrophin promoter and that they activate transcription synergistically with GABP. gabp 51-55 Ser7 Drosophila melanogaster 167-170 10934247-6 2000 Here, we assessed the role of GABP in synaptic gene expression and in the formation of postsynaptic specializations in vivo by perturbing its function during postsynaptic differentiation induced by neural agrin. gabp 30-34 agrin Homo sapiens 205-210 10934247-7 2000 We find that neural agrin-mediated activation of the AChR epsilon subunit promoter is abolished by the inhibition of GABP function. gabp 117-121 agrin Homo sapiens 20-25 9882338-9 1999 Introduction of this GABP site into the LAI virus yielded a specific gain of fitness in SupT1 cells, which contain little NF-kappaB protein. gabp 21-25 nuclear factor kappa B subunit 1 Homo sapiens 122-131 10218980-10 1999 We showed the requirement for GABP alpha/beta and c-Fos/c-Jun in endogenous OTR gene expression, using oligonucleotide GABP and AP-1 binding decoys to inhibit serum-induced increases in 125I-labeled OT antagonist binding to Hs578T cells. gabp 30-34 oxytocin receptor Homo sapiens 76-79 10218980-10 1999 We showed the requirement for GABP alpha/beta and c-Fos/c-Jun in endogenous OTR gene expression, using oligonucleotide GABP and AP-1 binding decoys to inhibit serum-induced increases in 125I-labeled OT antagonist binding to Hs578T cells. gabp 119-123 oxytocin receptor Homo sapiens 76-79 9882338-11 1999 Conversion of an NF-kappaB into a GABP binding site is likely to have occurred also during the worldwide spread of HIV-1, as we noticed the same LTR modification in subtype E isolates from Thailand. gabp 34-38 nuclear factor kappa B subunit 1 Homo sapiens 17-26 9192779-0 1997 GABP cooperates with c-Myb and C/EBP to activate the neutrophil elastase promoter. gabp 0-4 myeloblastosis oncogene Mus musculus 21-26 9512469-8 1998 Double-point mutant analysis indicated a major role for the NRF2/GABP site in the enhancer capacity of this element in brown fat cells. gabp 65-69 nuclear factor, erythroid derived 2, like 2 Mus musculus 60-64 9295016-3 1997 The GGAA element was specifically recognized by PU.1 in THP-1 monocytic cells and by PU.1 and GABP-related proteins in U937 promonocytic cells. gabp 94-98 Spi-1 proto-oncogene Homo sapiens 48-52 9234696-0 1997 GABP factors bind to a distal interleukin 2 (IL-2) enhancer and contribute to c-Raf-mediated increase in IL-2 induction. gabp 0-4 interleukin 2 Homo sapiens 30-43 9234696-0 1997 GABP factors bind to a distal interleukin 2 (IL-2) enhancer and contribute to c-Raf-mediated increase in IL-2 induction. gabp 0-4 interleukin 2 Homo sapiens 45-49 9234696-0 1997 GABP factors bind to a distal interleukin 2 (IL-2) enhancer and contribute to c-Raf-mediated increase in IL-2 induction. gabp 0-4 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 78-83 9234696-0 1997 GABP factors bind to a distal interleukin 2 (IL-2) enhancer and contribute to c-Raf-mediated increase in IL-2 induction. gabp 0-4 interleukin 2 Homo sapiens 105-109 9234696-7 1997 Introduction of point mutations suppressing GABP binding to the DSE interfered with the induction of the distal enhancer and the entire IL-2 promoter-enhancer, while overexpression of both GABP factors enhanced the IL-2 promoter-enhancer induction. gabp 44-48 interleukin 2 Homo sapiens 136-140 9234696-8 1997 Overexpression of BXB, a constitutive active version of c-Raf, and of further members of the Ras-Raf-Erk signal cascade exerted an increase of GABP-mediated promoter-enhancer induction. gabp 143-147 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 56-61 9234696-8 1997 Overexpression of BXB, a constitutive active version of c-Raf, and of further members of the Ras-Raf-Erk signal cascade exerted an increase of GABP-mediated promoter-enhancer induction. gabp 143-147 zinc fingers and homeoboxes 2 Homo sapiens 58-61 9234696-8 1997 Overexpression of BXB, a constitutive active version of c-Raf, and of further members of the Ras-Raf-Erk signal cascade exerted an increase of GABP-mediated promoter-enhancer induction. gabp 143-147 mitogen-activated protein kinase 1 Homo sapiens 101-104 9192779-0 1997 GABP cooperates with c-Myb and C/EBP to activate the neutrophil elastase promoter. gabp 0-4 CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus 31-36 9192779-0 1997 GABP cooperates with c-Myb and C/EBP to activate the neutrophil elastase promoter. gabp 0-4 elastase, neutrophil expressed Mus musculus 53-72 9192779-11 1997 Thus, GABP binds to the crucial mNE promoter ets site and powerfully activates its expression alone and in cooperation with the transcription factors c-Myb and C/EBP. gabp 6-10 myeloblastosis oncogene Mus musculus 150-155 9192779-11 1997 Thus, GABP binds to the crucial mNE promoter ets site and powerfully activates its expression alone and in cooperation with the transcription factors c-Myb and C/EBP. gabp 6-10 CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus 160-165 9138087-10 1997 These results suggest that GABP is a constitutively expressed protein and is involved in regulating rpL32 gene by post-transcriptional modifications. gabp 27-31 ribosomal protein L32 Homo sapiens 100-105 8663060-9 1996 Although GABP expression is not restricted to the hematopoietic lineage, its interaction with other specific factors may contribute to the tissue-specific expression of the gammac gene. gabp 9-13 interleukin 2 receptor subunit gamma Homo sapiens 173-179 8631833-0 1996 GABP mediates insulin-increased prolactin gene transcription. gabp 0-4 prolactin Rattus norvegicus 32-41 8631833-9 1996 These studies suggest that GABP mediates insulin-increased transcription of the prolactin gene. gabp 27-31 prolactin Rattus norvegicus 80-89 8806766-8 1996 Many features of the human COX5B promoter are conserved in the COX5B promoters of primates, in particular, the presence of a single binding site for NRF-1 and multiple sites for Sp1 and NRF-2/GABP. gabp 192-196 cytochrome c oxidase subunit 5B Homo sapiens 27-32 8806766-8 1996 Many features of the human COX5B promoter are conserved in the COX5B promoters of primates, in particular, the presence of a single binding site for NRF-1 and multiple sites for Sp1 and NRF-2/GABP. gabp 192-196 cytochrome c oxidase subunit 5B Homo sapiens 63-68 7565685-0 1995 A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP. gabp 121-125 cytochrome P450, family 2, subfamily d, polypeptide 9 Mus musculus 50-58 8642652-10 1996 The observed Raf-1-GABP synergism presumably involves phosphorylation of GABP subunits, as treatment of cells with Raf-1 kinase activators serum and 12-O-tetradecanoylphorbol-13-acetate increases phosphorylation of GABP in vivo. gabp 19-23 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 13-18 8642652-10 1996 The observed Raf-1-GABP synergism presumably involves phosphorylation of GABP subunits, as treatment of cells with Raf-1 kinase activators serum and 12-O-tetradecanoylphorbol-13-acetate increases phosphorylation of GABP in vivo. gabp 19-23 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 115-120 8642652-10 1996 The observed Raf-1-GABP synergism presumably involves phosphorylation of GABP subunits, as treatment of cells with Raf-1 kinase activators serum and 12-O-tetradecanoylphorbol-13-acetate increases phosphorylation of GABP in vivo. gabp 73-77 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 13-18 8642652-10 1996 The observed Raf-1-GABP synergism presumably involves phosphorylation of GABP subunits, as treatment of cells with Raf-1 kinase activators serum and 12-O-tetradecanoylphorbol-13-acetate increases phosphorylation of GABP in vivo. gabp 73-77 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 115-120 8642652-10 1996 The observed Raf-1-GABP synergism presumably involves phosphorylation of GABP subunits, as treatment of cells with Raf-1 kinase activators serum and 12-O-tetradecanoylphorbol-13-acetate increases phosphorylation of GABP in vivo. gabp 73-77 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 13-18 8642652-10 1996 The observed Raf-1-GABP synergism presumably involves phosphorylation of GABP subunits, as treatment of cells with Raf-1 kinase activators serum and 12-O-tetradecanoylphorbol-13-acetate increases phosphorylation of GABP in vivo. gabp 73-77 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 115-120 8642652-11 1996 However, GABP is not a target of Raf-1 kinase; instead, it is a substrate of mitogen-activated protein kinase (MAPK/ERK), since in vitro phosphorylation of GABP alpha and beta was achieved by the reconstituted protein kinase cascade but not with purified Raf-1 or MEK. gabp 9-13 mitogen-activated protein kinase 1 Homo sapiens 111-115 8642652-11 1996 However, GABP is not a target of Raf-1 kinase; instead, it is a substrate of mitogen-activated protein kinase (MAPK/ERK), since in vitro phosphorylation of GABP alpha and beta was achieved by the reconstituted protein kinase cascade but not with purified Raf-1 or MEK. gabp 9-13 mitogen-activated protein kinase 1 Homo sapiens 116-119 8642652-11 1996 However, GABP is not a target of Raf-1 kinase; instead, it is a substrate of mitogen-activated protein kinase (MAPK/ERK), since in vitro phosphorylation of GABP alpha and beta was achieved by the reconstituted protein kinase cascade but not with purified Raf-1 or MEK. gabp 9-13 GA binding protein transcription factor subunit alpha Homo sapiens 156-166 8642652-11 1996 However, GABP is not a target of Raf-1 kinase; instead, it is a substrate of mitogen-activated protein kinase (MAPK/ERK), since in vitro phosphorylation of GABP alpha and beta was achieved by the reconstituted protein kinase cascade but not with purified Raf-1 or MEK. gabp 9-13 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 255-260 8642652-11 1996 However, GABP is not a target of Raf-1 kinase; instead, it is a substrate of mitogen-activated protein kinase (MAPK/ERK), since in vitro phosphorylation of GABP alpha and beta was achieved by the reconstituted protein kinase cascade but not with purified Raf-1 or MEK. gabp 9-13 mitogen-activated protein kinase kinase 7 Homo sapiens 264-267 7565685-12 1995 We also conclude that GABP is a methylation-sensitive transcription factor and is a potential transcription activator of the male-specific Cyp 2d-9 promoter. gabp 22-26 cytochrome P450, family 2, subfamily d, polypeptide 9 Mus musculus 139-147 8821623-8 1995 The activities of both COX IV and COX Vb single site ets initiators are induced in vivo by coexpression with GABP alpha and beta cDNAs. gabp 109-113 cytochrome c oxidase subunit 4I1 Mus musculus 23-29 7918435-0 1994 Purification and characterization of nuclear factors binding to the negative regulatory element D of human apolipoprotein A-II promoter: a negative regulatory effect is reversed by GABP, an Ets-related protein. gabp 181-185 apolipoprotein A2 Homo sapiens 107-126 7918435-12 1994 Transcription from a minimal promoter containing elements AB, C, and D of apoA-II increased 1.5- to 1.6-fold when element D is deleted, as well as by promoter mutations which eliminated the binding of both AIID1 and/or AIID4 to element D, but permitted the binding of AIID2/GABP. gabp 274-278 apolipoprotein A2 Homo sapiens 74-81