PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 30717563-7 2018 The results of Western blot showed that orchinol could significantly down-regulate the protein expression levels of beta-catenin, Wnt3a, DvL2 and cyclinD1, and up-regulate the protein expression level of GSK-3beta(P<0.05, P<0.01, P<0.001). orchinol 40-48 catenin beta 1 Homo sapiens 116-128 30717563-7 2018 The results of Western blot showed that orchinol could significantly down-regulate the protein expression levels of beta-catenin, Wnt3a, DvL2 and cyclinD1, and up-regulate the protein expression level of GSK-3beta(P<0.05, P<0.01, P<0.001). orchinol 40-48 Wnt family member 3A Homo sapiens 130-135 30717563-7 2018 The results of Western blot showed that orchinol could significantly down-regulate the protein expression levels of beta-catenin, Wnt3a, DvL2 and cyclinD1, and up-regulate the protein expression level of GSK-3beta(P<0.05, P<0.01, P<0.001). orchinol 40-48 dishevelled segment polarity protein 2 Homo sapiens 137-141 30717563-7 2018 The results of Western blot showed that orchinol could significantly down-regulate the protein expression levels of beta-catenin, Wnt3a, DvL2 and cyclinD1, and up-regulate the protein expression level of GSK-3beta(P<0.05, P<0.01, P<0.001). orchinol 40-48 cyclin D1 Homo sapiens 146-154 30717563-7 2018 The results of Western blot showed that orchinol could significantly down-regulate the protein expression levels of beta-catenin, Wnt3a, DvL2 and cyclinD1, and up-regulate the protein expression level of GSK-3beta(P<0.05, P<0.01, P<0.001). orchinol 40-48 glycogen synthase kinase 3 beta Homo sapiens 204-213 30717563-8 2018 The above results suggest that orchinol can obviously inhibit the invasion and migration of SGC-7901 cells, which may be related to its inhibition of Wnt3a/beta-catenin signaling pathway and the proteins expression of downstream genes. orchinol 31-39 Wnt family member 3A Homo sapiens 150-155 30717563-8 2018 The above results suggest that orchinol can obviously inhibit the invasion and migration of SGC-7901 cells, which may be related to its inhibition of Wnt3a/beta-catenin signaling pathway and the proteins expression of downstream genes. orchinol 31-39 catenin beta 1 Homo sapiens 156-168