PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
30044647-1	2018	In this study, we synthesized a new congener series of N-sulphonylhydrazones designed as candidate ROCK inhibitors using the molecular hybridization of the clinically approved drug fasudil (1) and the IKK-beta inhibitor LASSBio-1524 (2).	n-sulphonylhydrazones	55-76	Rho associated coiled-coil containing protein kinase 1	Homo sapiens	99-103
30044647-1	2018	In this study, we synthesized a new congener series of N-sulphonylhydrazones designed as candidate ROCK inhibitors using the molecular hybridization of the clinically approved drug fasudil (1) and the IKK-beta inhibitor LASSBio-1524 (2).	n-sulphonylhydrazones	55-76	inhibitor of nuclear factor kappa B kinase subunit beta	Homo sapiens	201-209
30044647-4	2018	Molecular modelling studies provided insights into the possible binding modes of these N-sulphonylhydrazones, which present a new molecular architecture capable of being optimized and developed as therapeutically useful ROCK inhibitors.	n-sulphonylhydrazones	87-108	Rho associated coiled-coil containing protein kinase 1	Homo sapiens	220-224