PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
33483254-3	2021	SUGCT catalyzes the succinyl-CoA-dependent conversion of glutaric acid into glutaryl-CoA preventing urinary loss of the organic acid.	glutaric acid	57-70	succinyl-CoA glutarate-CoA transferase	Mus musculus	0-5
6207159-1	1983	Mitomycin C (MMC) was conjugated to horse anti-rat alpha-fetoprotein (AFP) antibody at the N-1a position through a glutaric acid-derived spacer arm.	glutaric acid	115-128	alpha-fetoprotein	Rattus norvegicus	70-73
33483254-8	2021	Our work demonstrates that SUGCT contributes to the production of glutaryl-CoA under conditions of low and pathologically high glutaric acid levels.	glutaric acid	127-140	succinyl-CoA glutarate-CoA transferase	Mus musculus	27-32
28936789-4	2018	The exposure of different cortical and striatal cell cultures to QUIN + GA resulted in cell death and stimulated different markers of oxidative stress, including reactive oxygen species (ROS) formation; changes in the activity of antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase; and depletion of endogenous antioxidants such as -SH groups and glutathione.	glutaric acid	72-74	catalase	Rattus norvegicus	280-288
33035499-7	2020	In striatum and cortex, NAC prevented glial cells activation (GFAP and Iba-1), decreased NGF, Bcl-2 and NeuN, the increase of lipid peroxidation and PARP induced by GA in both ages.	glutaric acid	165-167	poly (ADP-ribose) polymerase family, member 1	Mus musculus	149-153
33035499-8	2020	NAC protected against increased p75NTR induced by GA, but not in cortex of 21-day-old mice.	glutaric acid	50-52	nerve growth factor receptor (TNFR superfamily, member 16)	Mus musculus	32-38
32567100-4	2020	In the GA1 mouse model, deletion of Aass leads to a 4.3-, 3.8- and 3.2-fold decrease in the glutaric acid levels in urine, brain and liver, respectively.	glutaric acid	92-105	aminoadipate-semialdehyde synthase	Mus musculus	36-40
32567100-6	2020	These in vivo data demonstrate that the saccharopine pathway is the main source of glutaric acid production in the brain and periphery of a mouse model for GA1, and support the notion that pharmacological inhibition of AASS may represent an attractive strategy to treat GA1.	glutaric acid	83-96	aminoadipate-semialdehyde synthase	Mus musculus	219-223
30421167-1	2019	Dysfunction of basal ganglia neurons is a characteristic of glutaric acidemia type I (GA-I), an autosomal recessive inherited neurometabolic disease characterized by deficiency of glutaryl-CoA dehydrogenase (GCDH) and accumulation of glutaric acid (GA).	glutaric acid	60-73	glutaryl-CoA dehydrogenase	Rattus norvegicus	208-212
30421167-1	2019	Dysfunction of basal ganglia neurons is a characteristic of glutaric acidemia type I (GA-I), an autosomal recessive inherited neurometabolic disease characterized by deficiency of glutaryl-CoA dehydrogenase (GCDH) and accumulation of glutaric acid (GA).	glutaric acid	86-88	glutaryl-CoA dehydrogenase	Rattus norvegicus	208-212
30421167-4	2019	We found that GA injection caused delay procedural learning; increase of cytokine concentration, oxidative markers, and caspase levels; decrease of antioxidant defenses; and alteration of acetylcholinesterase (AChE) activity.	glutaric acid	14-16	acetylcholinesterase	Rattus norvegicus	188-208
30421167-4	2019	We found that GA injection caused delay procedural learning; increase of cytokine concentration, oxidative markers, and caspase levels; decrease of antioxidant defenses; and alteration of acetylcholinesterase (AChE) activity.	glutaric acid	14-16	acetylcholinesterase	Rattus norvegicus	210-214
30129250-1	2018	The deficiency of the enzyme glutaryl-CoA dehydrogenase, known as glutaric acidemia type I (GA-I), leads to the accumulation of glutaric acid (GA) and glutarilcarnitine (C5DC) in the tissues and body fluids, unleashing important neurotoxic effects.	glutaric acid	92-94	glutaryl-CoA dehydrogenase	Homo sapiens	29-55
30129250-1	2018	The deficiency of the enzyme glutaryl-CoA dehydrogenase, known as glutaric acidemia type I (GA-I), leads to the accumulation of glutaric acid (GA) and glutarilcarnitine (C5DC) in the tissues and body fluids, unleashing important neurotoxic effects.	glutaric acid	66-79	glutaryl-CoA dehydrogenase	Homo sapiens	29-55
30129250-1	2018	The deficiency of the enzyme glutaryl-CoA dehydrogenase, known as glutaric acidemia type I (GA-I), leads to the accumulation of glutaric acid (GA) and glutarilcarnitine (C5DC) in the tissues and body fluids, unleashing important neurotoxic effects.	glutaric acid	143-145	glutaryl-CoA dehydrogenase	Homo sapiens	29-55
32306145-1	2020	Glutaric aciduria type I (GA1; OMIM #231670) is an autosomal recessively inherited and treatable disorder characterized by the accumulation and irregular excretion of glutaric acid due to a defect in the glutaryl-CoA dehydrogenase enzyme involved in the catabolic pathways of L-lysine, L-hydroxylysine, and L-tryptophan.	glutaric acid	167-180	glutaryl-CoA dehydrogenase	Homo sapiens	204-230
32150882-7	2020	The enzyme activity evaluation results showed that both GA and glutaric acid displayed alpha-glucosidase inhibition activity, and GA-glutaric acid cocrystals showed strengthened alpha-glucosidase inhibition activity at a moderate concentration, which is attributed to synergism of the two components.	glutaric acid	63-76	sucrase-isomaltase	Homo sapiens	87-104
32150882-7	2020	The enzyme activity evaluation results showed that both GA and glutaric acid displayed alpha-glucosidase inhibition activity, and GA-glutaric acid cocrystals showed strengthened alpha-glucosidase inhibition activity at a moderate concentration, which is attributed to synergism of the two components.	glutaric acid	133-146	sucrase-isomaltase	Homo sapiens	178-195
29292490-4	2018	The cultured skin fibroblast showed reduced glutaryl-CoA dehydrogenase activity (0.16 mg protein per min).The initial diagnostic urine glutaric acid level for this patient was 1,784 mumol/mmol creatinine.	glutaric acid	135-148	glutaryl-CoA dehydrogenase	Homo sapiens	44-70
29351921-8	2018	GA (2 mM) markedly inhibited the activity of UGT1A7 by 89.4% and UGT1A9 by 32.8%.	glutaric acid	0-2	UDP glucuronosyltransferase family 1 member A7	Homo sapiens	45-51
29351921-8	2018	GA (2 mM) markedly inhibited the activity of UGT1A7 by 89.4% and UGT1A9 by 32.8%.	glutaric acid	0-2	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	65-71
28766179-1	2018	Glutaric aciduria type 3 (GA3) is associated with decreased conversion of free glutaric acid to glutaryl-coA, reflecting deficiency of succinate-hydroxymethylglutarate coA-transferase, caused by variants in the SUGCT (C7orf10) gene.	glutaric acid	79-92	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	0-29
28766179-1	2018	Glutaric aciduria type 3 (GA3) is associated with decreased conversion of free glutaric acid to glutaryl-coA, reflecting deficiency of succinate-hydroxymethylglutarate coA-transferase, caused by variants in the SUGCT (C7orf10) gene.	glutaric acid	79-92	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	211-216
29458885-2	2018	GCDH gene mutation can lead to glutaric acid and 3- OH glutaric acid accumulation, with clinical manifestation of neuronal damage, brain atrophy, microencephalic macrocephaly, decreased coordination of swallowing, poor muscle coordination, spasticity, and severe dystonic movement disorder.	glutaric acid	31-44	glutaryl-CoA dehydrogenase	Homo sapiens	0-4
28699143-1	2018	Glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in tissues and body fluids.	glutaric acid	152-165	glutaryl-CoA dehydrogenase	Homo sapiens	90-116
28699143-1	2018	Glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in tissues and body fluids.	glutaric acid	152-165	glutaryl-CoA dehydrogenase	Homo sapiens	118-122
28699143-1	2018	Glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in tissues and body fluids.	glutaric acid	26-28	glutaryl-CoA dehydrogenase	Homo sapiens	90-116
28699143-1	2018	Glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in tissues and body fluids.	glutaric acid	26-28	glutaryl-CoA dehydrogenase	Homo sapiens	118-122
28545977-0	2017	Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.	glutaric acid	9-22	dehydrogenase E1 and transketolase domain containing 1	Mus musculus	33-39
28545977-2	2017	GCDH deficiency leads to disruption of l-lysine degradation with characteristic accumulation of glutarylcarnitine and neurotoxic glutaric acid (GA), glutaryl-CoA, 3-hydroxyglutaric acid (3-OHGA).	glutaric acid	129-142	glutaryl-Coenzyme A dehydrogenase	Mus musculus	0-4
28545977-2	2017	GCDH deficiency leads to disruption of l-lysine degradation with characteristic accumulation of glutarylcarnitine and neurotoxic glutaric acid (GA), glutaryl-CoA, 3-hydroxyglutaric acid (3-OHGA).	glutaric acid	144-146	glutaryl-Coenzyme A dehydrogenase	Mus musculus	0-4
25968119-3	2015	Upon Lys treatment, Gcdh-/- astrocytes synthetized and released GA and 3-hydroxyglutaric acid (3HGA).	glutaric acid	64-66	glutaryl-Coenzyme A dehydrogenase	Mus musculus	20-24
27165598-2	2016	GCDH gene mutations cause glutaryl-CoA dehydrogenase deficiency and accumulation of glutaric acid and 3-hydroxyglutaric acid, resulting in damage of striatum and other brain nucleus and neurodegeneration.	glutaric acid	84-97	glutaryl-CoA dehydrogenase	Homo sapiens	0-4
25968119-7	2015	In contrast, Lys or GA direct exposure on Gcdh-/- or WT striatal neurons cultured in the absence of astrocytes was not toxic, indicating that neuronal death is mediated by astrocytes.	glutaric acid	20-22	glutaryl-Coenzyme A dehydrogenase	Mus musculus	42-46
25968119-8	2015	In summary, GCDH-defective astrocytes actively contribute to produce and accumulate GA and 3HGA when Lys catabolism is stressed.	glutaric acid	84-86	glutaryl-Coenzyme A dehydrogenase	Mus musculus	12-16
23623985-1	2013	The metabolic disorder glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of the pathologic metabolites glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in blood, urine and tissues.	glutaric acid	23-36	glutaryl-CoA dehydrogenase	Homo sapiens	99-125
24703693-6	2014	We further showed that glutarylation suppresses CPS1 enzymatic activity in cell lines, mice, and a model of glutaric acidemia type I disease, the last of which has elevated glutaric acid and glutaryl-CoA.	glutaric acid	108-121	carbamoyl-phosphate synthetase 1	Mus musculus	48-52
24205200-5	2013	METHODS: Rat pups were injected with GA (5 umol g of body weight-1, subcutaneously; twice per day; from 5th to 28th day of life), and were supplemented with NAC (150 mg/kg/day; intragastric gavage; for the same period).	glutaric acid	37-39	Body weight QTL 17	Rattus norvegicus	58-66
25811311-1	2015	Measurements of HO2 uptake coefficients (gamma) were made onto a variety of organic aerosols derived from glutaric acid, glyoxal, malonic acid, stearic acid, oleic acid, squalene, monoethanol amine sulfate, monomethyl amine sulfate, and two sources of humic acid, for an initial HO2 concentration of 1 x 10(9) molecules cm(-3), room temperature and at atmospheric pressure.	glutaric acid	106-119	heme oxygenase 2	Homo sapiens	16-19
25241940-5	2014	However, GA provoked a significant decrease of [(3)H]glutamate uptake in striatum from both WT and Gcdh(-/-) mice older than 7 days.	glutaric acid	9-11	glutaryl-Coenzyme A dehydrogenase	Mus musculus	99-103
23623985-1	2013	The metabolic disorder glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of the pathologic metabolites glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in blood, urine and tissues.	glutaric acid	23-36	glutaryl-CoA dehydrogenase	Homo sapiens	127-131
23623985-1	2013	The metabolic disorder glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of the pathologic metabolites glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in blood, urine and tissues.	glutaric acid	49-51	glutaryl-CoA dehydrogenase	Homo sapiens	99-125
23623985-1	2013	The metabolic disorder glutaric aciduria type 1 (GA1) is caused by deficiency of the mitochondrial glutaryl-CoA dehydrogenase (GCDH), leading to accumulation of the pathologic metabolites glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in blood, urine and tissues.	glutaric acid	49-51	glutaryl-CoA dehydrogenase	Homo sapiens	127-131
23859237-1	2013	Glutaric aciduria type 1 is an autosomal recessive disorder caused by deficiency of glutaryl-coenzyme A dehydrogenase, with accumulation of glutaric acid, 3-hydroxyglutaric acid and glutaconic acid.	glutaric acid	140-153	glutaryl-CoA dehydrogenase	Homo sapiens	84-117
21454630-1	2011	The inherited neurodegenerative disorder glutaric aciduria type 1 (GA1) results from mutations in the gene for the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), which leads to elevations of the dicarboxylates glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in brain and blood.	glutaric acid	41-54	glutaryl-Coenzyme A dehydrogenase	Mus musculus	143-169
22610679-2	2012	The most interesting feature of this phase transition is that every second glutaric acid molecule changes its conformation, and this fact results in the space-group symmetry change from P2(1)/c to P1.	glutaric acid	75-88	cyclin dependent kinase inhibitor 1A	Homo sapiens	186-191
21454630-1	2011	The inherited neurodegenerative disorder glutaric aciduria type 1 (GA1) results from mutations in the gene for the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), which leads to elevations of the dicarboxylates glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in brain and blood.	glutaric acid	41-54	glutaryl-Coenzyme A dehydrogenase	Mus musculus	171-175
21454630-1	2011	The inherited neurodegenerative disorder glutaric aciduria type 1 (GA1) results from mutations in the gene for the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), which leads to elevations of the dicarboxylates glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in brain and blood.	glutaric acid	67-69	glutaryl-Coenzyme A dehydrogenase	Mus musculus	143-169
21454630-1	2011	The inherited neurodegenerative disorder glutaric aciduria type 1 (GA1) results from mutations in the gene for the mitochondrial matrix enzyme glutaryl-CoA dehydrogenase (GCDH), which leads to elevations of the dicarboxylates glutaric acid (GA) and 3-hydroxyglutaric acid (3OHGA) in brain and blood.	glutaric acid	67-69	glutaryl-Coenzyme A dehydrogenase	Mus musculus	171-175
21698251-5	2011	GA administration potently elicited proliferation of astrocytes expressing S100beta followed by GFAP astrocytosis and nitrotyrosine staining lasting until P45.	glutaric acid	0-2	S100 calcium binding protein B	Rattus norvegicus	75-83
21183317-8	2011	The intrastriatal injection of an IL-1beta antibody (200 ng/2 mul) prevented the facilitation of GA-induced seizures by LPS.	glutaric acid	97-99	interleukin 1 beta	Rattus norvegicus	34-42
20923787-10	2011	Interestingly, treatment with clofibrate decreased cerebral and hepatic concentrations of glutaric acid in glutaryl-coenzyme A dehydrogenase-deficient mice.	glutaric acid	90-103	glutaryl-Coenzyme A dehydrogenase	Mus musculus	107-140
18609448-5	2008	Glutaric acid, a model dicarboxylate, trans-stimulated the uptake of [(14)C]zonampanel by OAT4, suggesting that zonampanel was transported by OAT4 via an exchange with dicarboxylate.	glutaric acid	0-13	solute carrier family 22 member 11	Homo sapiens	90-94
19491659-1	2009	In view of findings that various tumors express receptors for somatostatin, a new targeted cytotoxic analog of somatostatin, AN-162 (AEZS-124), consisting of doxorubicin linked through glutaric acid to the somatostatin octapeptide RC-121 was developed in our laboratory.	glutaric acid	185-198	somatostatin	Homo sapiens	62-74
19491659-1	2009	In view of findings that various tumors express receptors for somatostatin, a new targeted cytotoxic analog of somatostatin, AN-162 (AEZS-124), consisting of doxorubicin linked through glutaric acid to the somatostatin octapeptide RC-121 was developed in our laboratory.	glutaric acid	185-198	somatostatin	Homo sapiens	111-123
19491659-1	2009	In view of findings that various tumors express receptors for somatostatin, a new targeted cytotoxic analog of somatostatin, AN-162 (AEZS-124), consisting of doxorubicin linked through glutaric acid to the somatostatin octapeptide RC-121 was developed in our laboratory.	glutaric acid	185-198	somatostatin	Homo sapiens	111-123
19395260-1	2009	Benzylamides of pentanedioic acid were identified as inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) by high-throughput screening.	glutaric acid	16-33	RNA, U1 small nuclear 1	Homo sapiens	67-122
18775954-1	2008	Glutaric aciduria type 1 (GA1) is an autosomal recessive neurometabolic disorder caused by mutations in the glutaryl-CoA dehydrogenase gene (GCDH), leading to an accumulation and high excretion of glutaric acid and 3-hydroxyglutaric acid.	glutaric acid	197-210	glutaryl-CoA dehydrogenase	Homo sapiens	108-134
18775954-1	2008	Glutaric aciduria type 1 (GA1) is an autosomal recessive neurometabolic disorder caused by mutations in the glutaryl-CoA dehydrogenase gene (GCDH), leading to an accumulation and high excretion of glutaric acid and 3-hydroxyglutaric acid.	glutaric acid	197-210	glutaryl-CoA dehydrogenase	Homo sapiens	141-145
18609448-5	2008	Glutaric acid, a model dicarboxylate, trans-stimulated the uptake of [(14)C]zonampanel by OAT4, suggesting that zonampanel was transported by OAT4 via an exchange with dicarboxylate.	glutaric acid	0-13	solute carrier family 22 member 11	Homo sapiens	142-146
17722545-0	2007	Glutaric acid as a spacer facilitates improved intracellular uptake of LHRH-SPION into human breast cancer cells.	glutaric acid	0-13	gonadotropin releasing hormone 1	Homo sapiens	71-75
18306172-3	2008	In addition, the spectra show that a substantial amount of water molecules is trapped between the glutaric acid and the hydroxyapatite surface, indicating that water molecules may play a prominent role in the noncovalent interaction of the glutaric acid and the HAp surface.	glutaric acid	98-111	reticulon 3	Homo sapiens	262-265
18306172-3	2008	In addition, the spectra show that a substantial amount of water molecules is trapped between the glutaric acid and the hydroxyapatite surface, indicating that water molecules may play a prominent role in the noncovalent interaction of the glutaric acid and the HAp surface.	glutaric acid	240-253	reticulon 3	Homo sapiens	262-265
18404412-4	2008	More recently, organic anion transporters (OAT) 1 and 4 have been reported to be high-affinity transporters for GA and 3OHGA as well as D-2- and L-2-hydroxyglutaric acid (D2OHGA, L2OHGA).	glutaric acid	112-114	solute carrier family 22 (organic anion transporter), member 6	Mus musculus	15-55
17945191-6	2008	COX-1 in platelet lysates or isolated COX-1 selectively bound to an affinity matrix composed of immobilized BAs linked via glutaric acid to sepharose and this binding was reversed by ibuprofen or AA.	glutaric acid	123-136	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	0-5
17945191-6	2008	COX-1 in platelet lysates or isolated COX-1 selectively bound to an affinity matrix composed of immobilized BAs linked via glutaric acid to sepharose and this binding was reversed by ibuprofen or AA.	glutaric acid	123-136	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	38-43
17722545-2	2007	We demonstrate in this communication that inclusion of a small spacer molecule such as glutaric acid (Glu) in between SPION and LHRH increases further receptor mediated intracellular uptake.	glutaric acid	87-100	gonadotropin releasing hormone 1	Homo sapiens	128-132
17722545-2	2007	We demonstrate in this communication that inclusion of a small spacer molecule such as glutaric acid (Glu) in between SPION and LHRH increases further receptor mediated intracellular uptake.	glutaric acid	102-105	gonadotropin releasing hormone 1	Homo sapiens	128-132
15774829-10	2005	Apoptosis but not necrosis was detected at various stages (early: annexin-V; effector: caspase-3) after 24-48 h of incubation with GA, GC, or 3-OH-GA in OLN-93 but not in neuroblastoma or microglia cells.	glutaric acid	131-133	caspase 3	Rattus norvegicus	87-96
12798312-3	2003	Inhibitory potency of the primed-side GCP II inhibitors was found to be dependent on the number of methylene units between the hydroxamate group and pentanedioic acid.	glutaric acid	149-166	folate hydrolase 1	Homo sapiens	38-44
15262270-1	2004	Glutaric aciduria type I (GA I) is an autosomal recessive inherited metabolic disorder caused by deficiency of glutaryl-CoA dehydrogenase (GCD) resulting in the accumulation of 3-hydroxyglutaric acid (3OHG), glutaric acid and glutaconic acid in body fluids.	glutaric acid	186-199	glutaryl-CoA dehydrogenase	Rattus norvegicus	139-142
15505387-0	2004	Preliminary attempts to establish a rat model of striatal injury in glutaric acidaemia type I. Glutaric acidaemia type I (GA I) is caused by the deficiency of glutaryl-CoA dehydrogenase, resulting in accumulation of glutaric acid (GA) and 3- hydroxyglutaric acid (3-OH-GA) in blood and cerebrospinal fluid (CSF).	glutaric acid	122-124	glutaryl-CoA dehydrogenase	Rattus norvegicus	159-185
15505387-0	2004	Preliminary attempts to establish a rat model of striatal injury in glutaric acidaemia type I. Glutaric acidaemia type I (GA I) is caused by the deficiency of glutaryl-CoA dehydrogenase, resulting in accumulation of glutaric acid (GA) and 3- hydroxyglutaric acid (3-OH-GA) in blood and cerebrospinal fluid (CSF).	glutaric acid	231-233	glutaryl-CoA dehydrogenase	Rattus norvegicus	159-185
15505389-1	2004	The metabolic hallmark of glutaric aciduria type I (GA I) is the deficiency of glutaryl-CoA dehydrogenase (GCDH) with subsequent accumulation of glutaric acid, 3-hydroxglutaric acid (3-OH-GA) and glutaconic acid.	glutaric acid	26-39	glutaryl-CoA dehydrogenase	Homo sapiens	107-111
12723961-2	2003	The inhibitory potency of these thiol-based compounds against GCP II was found to be dependent on the number of methylene units between the thiol group and pentanedioic acid.	glutaric acid	156-173	folate hydrolase 1	Rattus norvegicus	62-68
11768583-0	2001	IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures.	glutaric acid	22-35	insulin like growth factor 1	Homo sapiens	0-5
12036373-5	2002	Furthermore, increasing the 23-membered lactam ring of 1 by one carbon atom (succinyl --> glutaric acid linker) gives a highly selective and potent antagonist 9 for the hMC3 receptor.	glutaric acid	93-106	melanocortin 3 receptor	Homo sapiens	172-176
11768583-0	2001	IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures.	glutaric acid	22-35	fibroblast growth factor 2	Homo sapiens	10-14
10759157-8	2000	We conclude from these results that 3-hydroxyglutaric acid and glutaric acid act as false neurotransmitters, in particular through NR1/2B, and that the extent of induced neurotoxicity is dependent on the temporal and spatial expression of NR1/2B in the CNS during maturation.	glutaric acid	45-58	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	131-137
11758903-2	2001	The kidney contains very high activity of aminocarboxymuconate-semialdehyde decarboxylase (ACMSD), which leads tryptophan into the glutaric acid pathway and then the TCA cycle, but not to the niacin pathway.	glutaric acid	131-144	aminocarboxymuconate semialdehyde decarboxylase	Rattus norvegicus	42-89
11758903-2	2001	The kidney contains very high activity of aminocarboxymuconate-semialdehyde decarboxylase (ACMSD), which leads tryptophan into the glutaric acid pathway and then the TCA cycle, but not to the niacin pathway.	glutaric acid	131-144	aminocarboxymuconate semialdehyde decarboxylase	Rattus norvegicus	91-96
10759157-8	2000	We conclude from these results that 3-hydroxyglutaric acid and glutaric acid act as false neurotransmitters, in particular through NR1/2B, and that the extent of induced neurotoxicity is dependent on the temporal and spatial expression of NR1/2B in the CNS during maturation.	glutaric acid	45-58	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	239-245
1986098-12	1991	If there is suspicion of glutaric aciduria, glutaryl-coenzyme A dehydrogenase should be measured in fibroblasts or lymphocytes even if glutaric acid is not increased in the urine.	glutaric acid	25-38	glutaryl-CoA dehydrogenase	Homo sapiens	44-77
8300996-1	1994	This disorder is caused by a defect in the mitochondrial enzyme glutaryl-coenzyme A dehydrogenase, resulting in permanent or episodic elevations of glutaric acid.	glutaric acid	148-161	glutaryl-CoA dehydrogenase	Homo sapiens	64-97
3177651-2	1988	However, when micromolar concentrations of glutaric acid or alpha-ketoglutaric acid were added in the presence of a out greater than in Na+ gradient, PAH uptake was accelerated greater than 20-fold and an overshoot of greater than fivefold was produced.	glutaric acid	43-56	phenylalanine hydroxylase	Rattus norvegicus	150-153
35537377-3	2022	Using 200 mM 5-AVA and 30 mM MSG initially with Gox, 67.1 mM of glutaric acid was produced.	glutaric acid	64-77	hydroxyacid oxidase 1	Homo sapiens	48-51