PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
7840649-1	1995	The metabolism of cis-epoxyeicosatrienoic acids (EETs), methyl cis-epoxyeicosatrienoates, and cis-epoxyeicosanoic acids by cytosolic epoxide hydrolase was studied to identify substrate structural features important for stereoselective metabolism and chiral diol formation.	cis-epoxyeicosatrienoic acids	18-47	epoxide hydrolase 2	Rattus norvegicus	123-150
7738183-2	1995	Microsomal fractions prepared from rabbit lung homogenates metabolized arachidonic acid through cytochrome P450 pathways, yielding cis-epoxyeicosatrienoic acids (EETs) and their hydration products, vic-dihydroxyeicosatrienoic acids, mid-chain cis-trans conjugated dienols, and 19- and 20-hydroxyeicosatetraenoic acids.	cis-epoxyeicosatrienoic acids	131-160	cytochrome P-450	Oryctolagus cuniculus	96-111
20140850-1	2010	BACKGROUND: Cytochrome P450 (CYP) 2J2 is a regulatory enzyme in the biosynthesis of biologically active CIS-epoxyeicosatrienoic acids (EETs).	cis-epoxyeicosatrienoic acids	104-133	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	12-37
31000184-1	2019	BACKGROUND: The cytochrome P-450 2J2 (CYP2J2) is known to be one of the major enzymes of epoxygenase pathway of arachidonic acid in extrahepatic tissues, which produces series of regioisomeric cis-epoxyeicosatrienoic acids (EETs) such as 5,6-, 8,9-, 11,12-, and 14,15-EETs.	cis-epoxyeicosatrienoic acids	193-222	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	16-36
31000184-1	2019	BACKGROUND: The cytochrome P-450 2J2 (CYP2J2) is known to be one of the major enzymes of epoxygenase pathway of arachidonic acid in extrahepatic tissues, which produces series of regioisomeric cis-epoxyeicosatrienoic acids (EETs) such as 5,6-, 8,9-, 11,12-, and 14,15-EETs.	cis-epoxyeicosatrienoic acids	193-222	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	38-44
25204827-2	2014	Located at the endoplasmic reticulum, CYP2J2 is responsible for epoxidation of endogenous arachidonic acid in cardiac tissue to produce cis-epoxyeicosatrienoic acids (EETs), which have anti-inflammatory and antifibrinolytic properties, and can protect endothelial cells from ischemic or hypoxic injuries.	cis-epoxyeicosatrienoic acids	136-165	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	38-44
29966295-1	2018	Cytochrome P450 2J2 (CYP2J2) is a known arachidonic acid (AA) epoxygenase that mediates the formation of four bioactive regioisomers of cis-epoxyeicosatrienoic acids (EETs).	cis-epoxyeicosatrienoic acids	136-165	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	0-19
29966295-1	2018	Cytochrome P450 2J2 (CYP2J2) is a known arachidonic acid (AA) epoxygenase that mediates the formation of four bioactive regioisomers of cis-epoxyeicosatrienoic acids (EETs).	cis-epoxyeicosatrienoic acids	136-165	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	21-27
22664166-8	2012	Moreover, we report a novel inhibitory mechanism because TGA stimulates the production of an anti-inflammatory P-450 eicosanoid metabolites (cis-epoxyeicosatrienoic acids [EETs]) in the lung.	cis-epoxyeicosatrienoic acids	141-170	T-box transcription factor 1	Homo sapiens	57-60
18716027-2	2008	Mouse CYP2J5 is abundant in the kidney where its products, the cis-epoxyeicosatrienoic acids (EETs), modulate sodium transport and vascular tone.	cis-epoxyeicosatrienoic acids	63-92	cytochrome P450, family 2, subfamily j, polypeptide 5	Mus musculus	6-12
20021200-5	2010	The purified enzyme was catalytically active towards aminopyrine, all-trans-retinoic acid, and particularly arachidonic acid forming 20-HETE, 19-HETE, and 18-HETE (about 86% of the total) and 14,15-, 11,12-, 8,9-, and 5,6-EETs (cis-epoxyeicosatrienoic acids; about 14% of total), with a regioselectivity similar to that shown by the mammalian CYP2J2s.	cis-epoxyeicosatrienoic acids	228-257	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	343-349
14575523-1	2003	OBJECTIVE: Cytochrome P450 (CYP) 2J2 plays an important role in the biosynthesis of the biologically active cis-epoxyeicosatrienoic acids.	cis-epoxyeicosatrienoic acids	108-137	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	11-36
15864120-1	2005	CYP2J2 and CYP2C8 metabolize arachidonic acid (AA) to cis-epoxyeicosatrienoic acids (EETs), which play a central role in regulating renal tubular fluid-electrolyte transport and vascular tone.	cis-epoxyeicosatrienoic acids	54-83	cytochrome P450 family 2 subfamily J member 2	Homo sapiens	0-6
15864120-1	2005	CYP2J2 and CYP2C8 metabolize arachidonic acid (AA) to cis-epoxyeicosatrienoic acids (EETs), which play a central role in regulating renal tubular fluid-electrolyte transport and vascular tone.	cis-epoxyeicosatrienoic acids	54-83	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	11-17