PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 30052808-2 2019 The binary IL6:sIL6R complex is inactivated by sgp130 through the formation of the ternary IL6:sIL6R:sgp130 complex. sil6r 15-20 interleukin 6 Homo sapiens 11-14 30052808-2 2019 The binary IL6:sIL6R complex is inactivated by sgp130 through the formation of the ternary IL6:sIL6R:sgp130 complex. sil6r 95-100 interleukin 6 Homo sapiens 11-14 30052808-2 2019 The binary IL6:sIL6R complex is inactivated by sgp130 through the formation of the ternary IL6:sIL6R:sgp130 complex. sil6r 95-100 interleukin 6 Homo sapiens 16-19 23946454-7 2013 Furthermore, sIL6R mediated antiviral action via the p28 pathway and induced alpha interferon (IFN-alpha) by promoting the nuclear translocation of IFN regulatory factor 3 (IRF3) and NF-kappaB, which led to the activation of downstream IFN effectors, including 2",5"-oligoadenylate synthetase (OAS), double-stranded RNA-dependent protein kinase (PKR), and myxovirus resistance protein (Mx). sil6r 13-18 interferon alpha 1 Homo sapiens 77-104 23946454-7 2013 Furthermore, sIL6R mediated antiviral action via the p28 pathway and induced alpha interferon (IFN-alpha) by promoting the nuclear translocation of IFN regulatory factor 3 (IRF3) and NF-kappaB, which led to the activation of downstream IFN effectors, including 2",5"-oligoadenylate synthetase (OAS), double-stranded RNA-dependent protein kinase (PKR), and myxovirus resistance protein (Mx). sil6r 13-18 interferon regulatory factor 3 Homo sapiens 148-171 23946454-7 2013 Furthermore, sIL6R mediated antiviral action via the p28 pathway and induced alpha interferon (IFN-alpha) by promoting the nuclear translocation of IFN regulatory factor 3 (IRF3) and NF-kappaB, which led to the activation of downstream IFN effectors, including 2",5"-oligoadenylate synthetase (OAS), double-stranded RNA-dependent protein kinase (PKR), and myxovirus resistance protein (Mx). sil6r 13-18 interferon regulatory factor 3 Homo sapiens 173-177 23946454-7 2013 Furthermore, sIL6R mediated antiviral action via the p28 pathway and induced alpha interferon (IFN-alpha) by promoting the nuclear translocation of IFN regulatory factor 3 (IRF3) and NF-kappaB, which led to the activation of downstream IFN effectors, including 2",5"-oligoadenylate synthetase (OAS), double-stranded RNA-dependent protein kinase (PKR), and myxovirus resistance protein (Mx). sil6r 13-18 eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens 346-349 30291142-6 2018 Interestingly, the role of miR-590-5p in virus-triggered signaling was abolished in IL6R knockout cells, and this could be rescued by restoring the expression of the soluble IL6R (sIL6R) but not the membrane-bound IL6R (mIL6R), suggesting that sIL6R is indispensable for miR-590-5p in modulating the host antiviral response. sil6r 180-185 microRNA 590 Homo sapiens 27-34 30291142-6 2018 Interestingly, the role of miR-590-5p in virus-triggered signaling was abolished in IL6R knockout cells, and this could be rescued by restoring the expression of the soluble IL6R (sIL6R) but not the membrane-bound IL6R (mIL6R), suggesting that sIL6R is indispensable for miR-590-5p in modulating the host antiviral response. sil6r 180-185 interleukin 6 receptor Homo sapiens 84-88 30291142-6 2018 Interestingly, the role of miR-590-5p in virus-triggered signaling was abolished in IL6R knockout cells, and this could be rescued by restoring the expression of the soluble IL6R (sIL6R) but not the membrane-bound IL6R (mIL6R), suggesting that sIL6R is indispensable for miR-590-5p in modulating the host antiviral response. sil6r 180-185 interleukin 6 receptor Homo sapiens 174-178 30291142-6 2018 Interestingly, the role of miR-590-5p in virus-triggered signaling was abolished in IL6R knockout cells, and this could be rescued by restoring the expression of the soluble IL6R (sIL6R) but not the membrane-bound IL6R (mIL6R), suggesting that sIL6R is indispensable for miR-590-5p in modulating the host antiviral response. sil6r 180-185 interleukin 6 receptor Homo sapiens 174-178