PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 7852368-2 1995 Myeloperoxidase and eosinophil peroxidase catalyzed the oxidation of bromide ion by hydrogen peroxide (H2O2) and produced a brominating agent that reacted with amine compounds to form bromamines, which are long-lived oxidants containing covalent nitrogen-bromine bonds. bromamine 184-194 myeloperoxidase Homo sapiens 0-15 7852368-2 1995 Myeloperoxidase and eosinophil peroxidase catalyzed the oxidation of bromide ion by hydrogen peroxide (H2O2) and produced a brominating agent that reacted with amine compounds to form bromamines, which are long-lived oxidants containing covalent nitrogen-bromine bonds. bromamine 184-194 eosinophil peroxidase Homo sapiens 20-41 7852368-4 1995 Up to 1 mol of bromamine was produced per mole of H2O2, indicating that bromamine formation prevented the reduction of HOBr/OBr- by H2O2 and the loss of oxidizing and brominating activity. bromamine 15-24 leptin receptor Homo sapiens 120-123 7852368-4 1995 Up to 1 mol of bromamine was produced per mole of H2O2, indicating that bromamine formation prevented the reduction of HOBr/OBr- by H2O2 and the loss of oxidizing and brominating activity. bromamine 72-81 leptin receptor Homo sapiens 120-123 31468464-9 2019 Most importantly, the stimulatory effect of ibuprofen on production of inflammatory cytokines (TNF-alpha, IL-6) was inhibited by all tested bromamines. bromamine 140-150 tumor necrosis factor Homo sapiens 95-104 7852368-7 1995 In the presence of physiologic levels of both bromide (0.1 mM) and chloride (0.1 M), myeloperoxidase and eosinophil peroxidase produced mixtures of bromamines and chloramines containing 6 +/- 4% and 88 +/- 4% bromamine. bromamine 148-158 myeloperoxidase Homo sapiens 85-100 7852368-7 1995 In the presence of physiologic levels of both bromide (0.1 mM) and chloride (0.1 M), myeloperoxidase and eosinophil peroxidase produced mixtures of bromamines and chloramines containing 6 +/- 4% and 88 +/- 4% bromamine. bromamine 148-158 eosinophil peroxidase Homo sapiens 105-126 7852368-7 1995 In the presence of physiologic levels of both bromide (0.1 mM) and chloride (0.1 M), myeloperoxidase and eosinophil peroxidase produced mixtures of bromamines and chloramines containing 6 +/- 4% and 88 +/- 4% bromamine. bromamine 148-157 myeloperoxidase Homo sapiens 85-100 7852368-7 1995 In the presence of physiologic levels of both bromide (0.1 mM) and chloride (0.1 M), myeloperoxidase and eosinophil peroxidase produced mixtures of bromamines and chloramines containing 6 +/- 4% and 88 +/- 4% bromamine. bromamine 148-157 eosinophil peroxidase Homo sapiens 105-126 7852368-10 1995 Therefore, the amount of bromamine produced by myeloperoxidase or eosinophil peroxidase was equal to the amount of bromide oxidized by the enzyme. bromamine 25-34 myeloperoxidase Homo sapiens 47-62 7852368-10 1995 Therefore, the amount of bromamine produced by myeloperoxidase or eosinophil peroxidase was equal to the amount of bromide oxidized by the enzyme. bromamine 25-34 eosinophil peroxidase Homo sapiens 66-87 31468464-9 2019 Most importantly, the stimulatory effect of ibuprofen on production of inflammatory cytokines (TNF-alpha, IL-6) was inhibited by all tested bromamines. bromamine 140-150 interleukin 6 Homo sapiens 106-110 31468464-10 2019 These observations indicate that bromamines may neutralize massive production of TNF-alpha at sites of inflammation, a side effect of ibuprofen. bromamine 33-43 tumor necrosis factor Homo sapiens 81-90 11228954-1 2001 Ammonia can inhibit the formation of bromate in ozonated drinking water by reacting with free bromine (HOBr/OBr-), an intermediate in bromate formation, to form bromamines. bromamine 161-171 leptin receptor Homo sapiens 104-107