PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
30770784-10	2019	Moreover, LPA significantly increased the activity of the Ras-related C3 botulinum toxin substrate (Rac1) GTPase in SV40 MES13 cells, and the dominant-negative form of Rac1 partially inhibited the phosphorylation of p38 and upregulation of Egr1 and KLF5 induced by LPA.	mes13	121-126	Rac family small GTPase 1	Mus musculus	100-104
30770784-10	2019	Moreover, LPA significantly increased the activity of the Ras-related C3 botulinum toxin substrate (Rac1) GTPase in SV40 MES13 cells, and the dominant-negative form of Rac1 partially inhibited the phosphorylation of p38 and upregulation of Egr1 and KLF5 induced by LPA.	mes13	121-126	Rac family small GTPase 1	Mus musculus	168-172
28111010-4	2017	The expression of autotaxin, an LPA synthesis enzyme, and LPA receptor 1 was significantly increased in both mesangial cells (SV40 MES13) maintained in high-glucose media and the kidney cortex of diabetic db/db mice.	mes13	131-136	ectonucleotide pyrophosphatase/phosphodiesterase 2	Mus musculus	18-27
28111010-4	2017	The expression of autotaxin, an LPA synthesis enzyme, and LPA receptor 1 was significantly increased in both mesangial cells (SV40 MES13) maintained in high-glucose media and the kidney cortex of diabetic db/db mice.	mes13	131-136	lysophosphatidic acid receptor 1	Mus musculus	58-72
28111010-6	2017	Transforming growth factor (TGF)beta expression and Smad-2/3 phosphorylation were upregulated in SV40 MES13 cells by LPA stimulation or in the kidney cortex of db/db mice, and this was blocked by ki16425 treatment.	mes13	102-107	SMAD family member 2	Mus musculus	52-60
28111010-8	2017	LPA treatment of SV40 MES13 cells increased phosphorylated glycogen synthase kinase (GSK)3beta at Ser9 and induced translocation of sterol regulatory element-binding protein (SREBP)1 into the nucleus.	mes13	22-27	sterol regulatory element binding transcription factor 1	Mus musculus	175-182
27373678-4	2016	Thus, we studied the roles of Suv39h1 in HG-induced effects in MES13 (mouse mesangial) cells.	mes13	63-68	suppressor of variegation 3-9 1	Mus musculus	30-37
20664297-9	2010	IL-18 mRNA and protein expression were significantly upregulated by AngII (p < 0.05) and LPS (p < 0.01), but not PDGF-BB, in primary MCs and a MC line (MES13).	mes13	158-163	interleukin 18	Homo sapiens	0-5
24156434-8	2013	Further studies in HeLa, MES13 and HUVEC cell lines revealed that GPV could be efficiently expressed on the surface by itself in HeLa and MES13 cells, but not in HUVEC, suggesting different behaviors of the GPIb-IX-V complex in difference cell lines.	mes13	25-30	glycoprotein 5 (platelet)	Mus musculus	66-69