PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
29377518-1	2018	Flagellin (FliC) can act as a carrier protein in the preparation of conjugate vaccines to elicit a T-cell-dependent immune response and as an intrinsic adjuvant to activate the toll-like receptor 5 (TLR5) to enhance vaccine potency.	flic	11-15	toll like receptor 5	Homo sapiens	177-197
30838179-1	2019	The host immune system is constantly exposed to diverse microbial ligands, including flagellin (FliC; a ligand for TLR5 and NLRC4) and lipopolysaccharide (LPS; a ligand for TLR4), which could induce immune tolerance to subsequent exposure.	flic	96-100	toll-like receptor 5	Mus musculus	115-119
30838179-1	2019	The host immune system is constantly exposed to diverse microbial ligands, including flagellin (FliC; a ligand for TLR5 and NLRC4) and lipopolysaccharide (LPS; a ligand for TLR4), which could induce immune tolerance to subsequent exposure.	flic	96-100	NLR family, CARD domain containing 4	Mus musculus	124-129
29377518-1	2018	Flagellin (FliC) can act as a carrier protein in the preparation of conjugate vaccines to elicit a T-cell-dependent immune response and as an intrinsic adjuvant to activate the toll-like receptor 5 (TLR5) to enhance vaccine potency.	flic	11-15	toll like receptor 5	Homo sapiens	199-203
15472329-3	2004	sfpA was detected in DEC3F SF EHEC O157:H- strain 493/89, each of 107 SF EHEC O157:H- clinical isolates, and 14 Shiga toxin-negative SF E. coli O157:H- strains which contained eae, which encodes gamma-intimin, and fliC, which encodes the H7 antigen.	flic	214-218	w0006	Escherichia coli	0-4
28479111-5	2017	In the present study, FLiC (flagellin molecule sequence from Pseudomonas aeruginosa) was used as a TLR5 agonist.	flic	22-26	toll like receptor 5	Homo sapiens	99-103
17584736-6	2007	Here we show that GCK is required for JNK and, unexpectedly, p38 activation by three bacterial PAMPs, lipopolysaccharide, peptidoglycan, and flagellin (FliC).	flic	152-156	mitogen-activated protein kinase 14	Homo sapiens	61-64
29176760-8	2017	Results showed that FliC as adjuvant for immunization targeting ovalbumin was able to stimulate a gut mucosal and systemic antibody response independently of the immunization route.	flic	20-24	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	64-73
25766593-5	2015	FliC was used as an adjuvant and administered with the GP5 to C57BL/6 mice via intraperitoneal injection.	flic	0-4	glycoprotein 5 (platelet)	Mus musculus	55-58
25766593-7	2015	These results indicate that FliC is an effective adjuvant, increasing the induction of antibodies against GP5 with the induction of both humoral and cellular immune responses.	flic	28-32	glycoprotein V platelet	Homo sapiens	106-109
23306365-4	2013	Mice immunized with the fused FimH.FliC protein induced significantly higher humoral (IgG1 and IgG2a) and cellular (IFN-gamma and IL-4) immune responses than with FimH alone or FimH admixed with FliC.	flic	35-39	LOC105243590	Mus musculus	86-90
23306365-4	2013	Mice immunized with the fused FimH.FliC protein induced significantly higher humoral (IgG1 and IgG2a) and cellular (IFN-gamma and IL-4) immune responses than with FimH alone or FimH admixed with FliC.	flic	35-39	immunoglobulin heavy variable V1-9	Mus musculus	95-100
23306365-4	2013	Mice immunized with the fused FimH.FliC protein induced significantly higher humoral (IgG1 and IgG2a) and cellular (IFN-gamma and IL-4) immune responses than with FimH alone or FimH admixed with FliC.	flic	35-39	interferon gamma	Mus musculus	116-125
23306365-4	2013	Mice immunized with the fused FimH.FliC protein induced significantly higher humoral (IgG1 and IgG2a) and cellular (IFN-gamma and IL-4) immune responses than with FimH alone or FimH admixed with FliC.	flic	35-39	interleukin 4	Mus musculus	130-134
11401982-9	2001	IRAK activation was rapid in HeNC2 cells, with maximal activity observed after 5 min of treatment with FliC.	flic	103-107	interleukin-1 receptor-associated kinase 1	Mus musculus	0-4