PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 29748606-7 2018 Titration studies indicated that CC2C6 shares a common CD47-epitope with B6H12. b6h12 73-78 CD47 molecule Homo sapiens 55-59 30311702-12 2019 When human RBCs were preincubated with CD47 antibodies B6H12 or 2D3, phagocytosis was induced only after B6H12 incubation, indicating the lower phagocytic activity of porcine monocytes with human cells requires interaction between porcine SIRPA and human CD47. b6h12 55-60 CD47 molecule Homo sapiens 39-43 26840086-9 2016 B6H12 treatment also acutely inhibited EGF-induced EGFR tyrosine phosphorylation. b6h12 0-5 epidermal growth factor receptor Homo sapiens 51-55 18186923-9 2008 The function-blocking anti-CD47/IAP antibody Bric 126 inhibited changes in membrane potential, tyrosine phosphorylation, and elevation of relative levels of aggrecan mRNA induced by mechanical stimulation, whereas in the presence of B6H12, an antibody that has partial agonist activity, a membrane depolarisation rather than a membrane hyperpolarisation response was induced by mechanical stimulation. b6h12 233-238 CD47 molecule Homo sapiens 27-31 18186923-9 2008 The function-blocking anti-CD47/IAP antibody Bric 126 inhibited changes in membrane potential, tyrosine phosphorylation, and elevation of relative levels of aggrecan mRNA induced by mechanical stimulation, whereas in the presence of B6H12, an antibody that has partial agonist activity, a membrane depolarisation rather than a membrane hyperpolarisation response was induced by mechanical stimulation. b6h12 233-238 ATPase phospholipid transporting 8B1 Homo sapiens 45-49 15854275-14 2005 It is suggested that the soluble B6H12 exerts a negative effect on the maturation and function of in vitro cultured DCs due to inhibition of NF-kappaB binding activity. b6h12 33-38 nuclear factor kappa B subunit 1 Homo sapiens 141-150 10891456-6 2000 Furthermore, the dominant-negative form of CDC42 completely blocked B6H12-induced morphologic and functional changes without inhibiting phorbol 12-myristate 13-acetate-induced spreading on FN in BALL cells, whereas the dominant-negative form of Rac1 inhibited all these changes. b6h12 68-73 cell division cycle 42 Homo sapiens 43-48 8992983-5 1997 IAP cross-linking with B6H12 or BRIC126, but not 2D3, transduces costimulatory signals within highly purified CD3-activated T lymphocytes, i.e., enhancement of proliferation, CD25 expression, and IL-2 secretion, while no effect was observed upon CD2 stimulation. b6h12 23-28 CD47 molecule Homo sapiens 0-3 7662966-5 1995 Neither platelet aggregation nor intracellular Ca2+ elevation after stimulation was influenced by the anti-IAP antibody, B6H12, which was reported to be inhibitory for other beta 3 integrins. b6h12 121-126 CD47 molecule Homo sapiens 107-110 34471125-3 2021 We present the crystal structure of full length CD47 bound to the function-blocking antibody B6H12. b6h12 93-98 CD47 molecule Homo sapiens 48-52