PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 27900346-0 2016 Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. zfn 45-48 C-C motif chemokine receptor 5 Homo sapiens 58-62 22436965-9 2013 On the other hand, binding to and modification of the CCR5-ZFN site by a ZFN was relatively inefficient. zfn 59-62 C-C motif chemokine receptor 5 Homo sapiens 54-58 28941328-3 2018 In this study, ZFN technology was applied to induce a mutation in the binding domain region of SOX6 to reactivate gamma-globin expression. zfn 15-18 SRY-box transcription factor 6 Homo sapiens 95-99 30997769-4 2019 In this paper, we report the generation of modified pigs with ZFN mediated disruption of the GGTA1 gene encoding the enzyme responsible for synthesis of Galalpha1,3Gal antigens. zfn 62-65 N-acetyllactosaminide alpha-1,3-galactosyltransferase Sus scrofa 93-98 30645618-0 2019 Effect of ZFN-edited myostatin loss-of-function mutation on gut microbiota in Meishan pigs. zfn 10-13 myostatin Sus scrofa 21-30 30645618-5 2019 In this study, by sequencing 16S rRNA collected from rectum, we investigated the effects of ZFN-mediated myostatin (MSTN) loss-of-function mutation (MSTN-/-) on gut microbiota in Meishan pigs. zfn 92-95 myostatin Sus scrofa 105-114 30645618-5 2019 In this study, by sequencing 16S rRNA collected from rectum, we investigated the effects of ZFN-mediated myostatin (MSTN) loss-of-function mutation (MSTN-/-) on gut microbiota in Meishan pigs. zfn 92-95 myostatin Sus scrofa 116-120 30645618-5 2019 In this study, by sequencing 16S rRNA collected from rectum, we investigated the effects of ZFN-mediated myostatin (MSTN) loss-of-function mutation (MSTN-/-) on gut microbiota in Meishan pigs. zfn 92-95 myostatin Sus scrofa 149-153 30645618-9 2019 Thus, it is concluded that ZFN-mediated MSTN loss-of-function mutation did not have any adverse effect on the gut microbiota in Meishan pigs. zfn 27-30 myostatin Sus scrofa 40-44