PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 21238428-1 2011 Recombinant human interleukin-11 (rhIL-11) has been shown to increase platelet counts in animals and humans and is the only drug approved for its use in chemotherapy-induced thrombocytopenia (CIT). cit 192-195 interleukin 11 Homo sapiens 18-32 18313196-2 2008 The two chlorinated substances CIT and DCOIT significantly decreased the amount of total cellular glutathione (GSx) in a dose and time dependent manner. cit 31-34 ATP binding cassette subfamily C member 1 Homo sapiens 111-114 18986840-2 2009 The CIT regimen, represented by recombinant IFNgamma, anti-alpha crystalline monoclonal IgA antibody and IL-4 neutralizing polyclonal antibody, reduced the 8-week relapse of viable bacterial counts in the lungs most significantly, when CIT was inoculated during the 5th week post infection, i.e. during the 3rd week of chemotherapy. cit 4-7 interferon gamma Mus musculus 44-52 18986840-2 2009 The CIT regimen, represented by recombinant IFNgamma, anti-alpha crystalline monoclonal IgA antibody and IL-4 neutralizing polyclonal antibody, reduced the 8-week relapse of viable bacterial counts in the lungs most significantly, when CIT was inoculated during the 5th week post infection, i.e. during the 3rd week of chemotherapy. cit 4-7 interleukin 4 Mus musculus 105-109 17002262-1 2006 Amgen Inc is developing AMG-531, a peptibody that binds to the thrombopoietin receptor Mpl, for the potential treatment of immune thrombocytopenic purpura (ITP), chemotherapy-induced thrombocytopenia (CIT) and thrombocytopenia in myelodysplastic syndrome (MDS). cit 201-204 MPL proto-oncogene, thrombopoietin receptor Homo sapiens 87-90 17825933-4 2007 These findings indicate that pictures of faces can be used in a P300 based CIT, and that mere recognition is not sufficient for successful detection of concealed information. cit 75-78 E1A binding protein p300 Homo sapiens 64-68 17037726-8 2006 RESULTS: After reperfusion, the expression of IRAK-4 were largely depressed in CIT than that of IVT and the control group (P < 0.01), and furthermore, the serum TNF-alpha level, proportion of hepatocyte apoptosis and severity of hepatocyte injury were also lower than the latter. cit 79-82 interleukin-1 receptor-associated kinase 4 Rattus norvegicus 46-52 16858078-11 2006 The proportion of cTnI methods that demonstrated commutability for the CIT cRM was 45%; for the CI cRM, 39% of methods demonstrated commutability. cit 71-74 troponin I3, cardiac type Homo sapiens 18-22 16650410-5 2006 CIT was rapidly inhibited upon addition of an oligonucleotide that competed for the 18S rRNA site complementary to the RPS18C leader and interfered with polysome assembly at the transcript. cit 0-3 ribosomal protein S18 Triticum aestivum 119-124 12804041-1 2003 Chemoimmunotherapy (CIT) with interleukin-2, interferon-alpha2a, and 5-fluorouracil is an accepted treatment option of metastatic renal cell carcinoma (mRCC). cit 20-23 interleukin 2 Homo sapiens 30-43 12804041-1 2003 Chemoimmunotherapy (CIT) with interleukin-2, interferon-alpha2a, and 5-fluorouracil is an accepted treatment option of metastatic renal cell carcinoma (mRCC). cit 20-23 interferon alpha 2 Homo sapiens 45-63 10528215-4 1999 Similarly, E-selectin ligand is preferentially expressed on CD4+ T cells infiltrating the skin (24 +/- 2%), but only on very few CD4+ T cells infiltrating the colon (CIT; 1.3 +/- 0.8%). cit 166-169 E-selectin Sus scrofa 11-21 10528215-7 1999 Furthermore, CIT depleted of cells expressing functional P-selectin ligand were able to induce colitis upon transfer, suggesting that induction of colitis in this model may be independent of E- and P-selectin. cit 13-16 selectin P Sus scrofa 57-67 10490784-9 1999 They also indicate that the impaired CIT sometimes observed returns to normal after weight reduction suggesting that it is secondary to a decrease in glucose uptake induced by obesity-associated insulin resistance. cit 37-40 insulin Homo sapiens 195-202 1954811-10 1991 CONCLUSIONS: Glycemic control improved with both methods of insulin treated patients achieved satisfactory glycemic control (HbA1 less than 50 mmol hydroxymethylfurfural/mol Hb), whereas only 3 of 10 CIT-treated patients achieved this CSII. cit 200-203 insulin Homo sapiens 60-67 10366978-4 1999 RESULTS: Compared with that in HST, the expression of T beta R I HT was significantly lower than in HST and CIT (P < 0.01). cit 108-111 transforming growth factor beta receptor 1 Homo sapiens 54-64 7530621-6 1994 Diabetic patients with conventional insulin therapy (CIT; n = 12) had low IGF-1 (0.57 +/- 0.07 U/ml) compared with patients with continuous subcutaneous insulin infusion (CSII; n = 12; 0.75 +/- 0.08 U/ml; P < 0.05) and intraportal insulin infusion (IPII; n = 12; 1.07 +/- 10.05 U/ml; P < 0.05). cit 53-56 insulin Homo sapiens 36-43 7530621-6 1994 Diabetic patients with conventional insulin therapy (CIT; n = 12) had low IGF-1 (0.57 +/- 0.07 U/ml) compared with patients with continuous subcutaneous insulin infusion (CSII; n = 12; 0.75 +/- 0.08 U/ml; P < 0.05) and intraportal insulin infusion (IPII; n = 12; 1.07 +/- 10.05 U/ml; P < 0.05). cit 53-56 insulin like growth factor 1 Homo sapiens 74-79 8514459-1 1993 We had earlier shown that tumor-bearing results in an inactivation of IL-2-dependent effector cells by host macrophage-derived PGE2, and that chronic indomethacin therapy (CIT) aimed at blocking prostaglandin synthesis, combined with multiple rounds of IL-2, can cure experimental metastases of a variety of tumors in mice. cit 172-175 interleukin 2 Mus musculus 253-257 3300667-8 1987 Following the shift from CIT to CSII, HDL2-chol rose further (P less than 0.05), whereas HDL3-chol remained unchanged. cit 25-28 junctophilin 3 Homo sapiens 38-42 2337895-5 1990 CIT alone retarded tumor growth and stimulated cytotoxic activity in splenocytes as well as tumor-infiltrating lymphocytes against YAC-1 lymphoma and EAT targets but resulted in no cure. cit 0-3 ADP-ribosyltransferase 1 Mus musculus 131-136 2090199-12 1990 CIT + 3 rounds of IL-2 reduced the median colony counts from 40 to 0 and improved the survival from a median of 66 (control) to 120 days (40% surviving 260 + days). cit 0-3 interleukin 2 Mus musculus 18-22 2090199-13 1990 CIT + four or five rounds of IL-2 caused long-term (260 + days) survival of 80% mice, most surviving 400 + days. cit 0-3 interleukin 2 Mus musculus 29-33 34672825-7 2021 For HER2+ patients, use of CIT treatment downtrended with progression of pathological stage, from 70.1% (stage I) to 58.1% (stage III). cit 27-30 erb-b2 receptor tyrosine kinase 2 Homo sapiens 4-8 3318256-4 1987 We obtained better blood glucose control both by CSII and CBII than by CIT, with significant reduction of HbA1 values. cit 71-74 hemoglobin subunit alpha 1 Homo sapiens 106-110 3300667-9 1987 When CSII was changed to CIT, the HDL3-chol level decreased (P less than 0.02), but HDL2-chol remained constant. cit 25-28 HDL3 Homo sapiens 34-38 32638524-4 2021 To address this, we investigated effects of adolescent chronic intermittent toluene (CIT) inhalation on gene expression and DNA methylation profiles within the rat medial prefrontal cortex (mPFC), which undergoes maturation throughout adolescence and has been implicated in toluene-induced cognitive deficits. cit 85-88 complement factor properdin Mus musculus 190-194 4075944-7 1985 We conclude that elevated GFR values can be reduced toward normal level by insulin pump treatment for 1 yr. Retinal morphology was found to deteriorate in four of 12 CIT subjects and in three of 12 CSII subjects. cit 166-169 insulin Homo sapiens 75-82 968323-0 1976 [Evaluation of serum alpha-1-antitrypsin using trypsin inhibition capacity (CIT). cit 76-79 serpin family A member 1 Homo sapiens 21-40 32638524-6 2021 We demonstrate for the first time that adolescent CIT exposure results in dynamic regulation of the mPFC transcriptome likely relating to acute inflammatory responses and persistent deficits in synaptic plasticity. cit 50-53 complement factor properdin Mus musculus 100-104 32404734-13 2020 CX3CR1+CD8+ therapy-responsive T-cells can be potentially used for monitoring disease response to CIT. cit 98-101 C-X3-C motif chemokine receptor 1 Homo sapiens 0-6 33212483-8 2021 Furthermore, analysis of the association between NLRP3 inflammasome and CIT response using six CIT response datasets revealed the predictive value of NLRP3 inflammasome for immunotherapy response of patients in diverse cancers. cit 72-75 NLR family pyrin domain containing 3 Homo sapiens 49-54 33212483-8 2021 Furthermore, analysis of the association between NLRP3 inflammasome and CIT response using six CIT response datasets revealed the predictive value of NLRP3 inflammasome for immunotherapy response of patients in diverse cancers. cit 72-75 NLR family pyrin domain containing 3 Homo sapiens 150-155 32404734-13 2020 CX3CR1+CD8+ therapy-responsive T-cells can be potentially used for monitoring disease response to CIT. cit 98-101 CD8a molecule Homo sapiens 7-10 32185224-3 2020 Here, we reported that the citron Rho-interacting serine/threonine kinase (CIT) promotes the HIF1a-CypA signaling and growth of PDAC cells. cit 75-78 citron rho-interacting serine/threonine kinase Homo sapiens 27-73 32226027-4 2020 CIT resulted in a dramatic expansion of cytotoxic CD4+ and CD8+ T cells and a subsequent reduction in viral loads. cit 0-3 CD4 antigen Mus musculus 50-53 32226027-4 2020 CIT resulted in a dramatic expansion of cytotoxic CD4+ and CD8+ T cells and a subsequent reduction in viral loads. cit 0-3 CD8a molecule Homo sapiens 59-62 32185224-3 2020 Here, we reported that the citron Rho-interacting serine/threonine kinase (CIT) promotes the HIF1a-CypA signaling and growth of PDAC cells. cit 75-78 hypoxia inducible factor 1 subunit alpha Homo sapiens 93-98 32185224-3 2020 Here, we reported that the citron Rho-interacting serine/threonine kinase (CIT) promotes the HIF1a-CypA signaling and growth of PDAC cells. cit 75-78 peptidylprolyl isomerase A Homo sapiens 99-103 32185224-6 2020 The knockdown of CIT in PDAC cells reduced the expression of CypA while overexpression of CIT promoted the expression of CypA. cit 17-20 peptidylprolyl isomerase A Homo sapiens 61-65 32185224-6 2020 The knockdown of CIT in PDAC cells reduced the expression of CypA while overexpression of CIT promoted the expression of CypA. cit 90-93 peptidylprolyl isomerase A Homo sapiens 121-125 32185224-7 2020 We observed that the effects of CIT on the expression of CypA relied on the transcriptional factor HIF1a, which was previously reported to transcriptionally activate the expression of CypA in PDAC cells. cit 32-35 peptidylprolyl isomerase A Homo sapiens 57-61 32185224-7 2020 We observed that the effects of CIT on the expression of CypA relied on the transcriptional factor HIF1a, which was previously reported to transcriptionally activate the expression of CypA in PDAC cells. cit 32-35 hypoxia inducible factor 1 subunit alpha Homo sapiens 99-104 32185224-7 2020 We observed that the effects of CIT on the expression of CypA relied on the transcriptional factor HIF1a, which was previously reported to transcriptionally activate the expression of CypA in PDAC cells. cit 32-35 peptidylprolyl isomerase A Homo sapiens 184-188 32185224-8 2020 Furthermore, the effects of CIT on apoptosis, cell cycle, proliferation, and colony formation of PDAC cells relied on its role in the regulation of CypA expression. cit 28-31 peptidylprolyl isomerase A Homo sapiens 148-152 32185224-9 2020 Collectively, our data showed that CIT promoted the activation of HIF1-CypA signaling and enhanced the growth of PDAC cells. cit 35-38 hypoxia inducible factor 1 subunit alpha Homo sapiens 66-70 32185224-9 2020 Collectively, our data showed that CIT promoted the activation of HIF1-CypA signaling and enhanced the growth of PDAC cells. cit 35-38 peptidylprolyl isomerase A Homo sapiens 71-75 31354046-1 2019 We investigate if PD-L1 expression and other clinical characteristics predict chemoimmunotherapy (CIT) benefits versus chemotherapy in advanced non-small-cell lung cancer. cit 98-101 CD274 molecule Homo sapiens 18-23 31434681-1 2019 Chronic lymphocytic leukemia patients with mutated immunoglobulin heavy-chain genes (IGHV-M), particularly those lacking poor-risk genomic lesions, often respond well to chemoimmunotherapy (CIT). cit 190-193 immunoglobulin heavy variable 3-69-1 (pseudogene) Homo sapiens 85-89 30746747-5 2019 CIT training resulted in reductions in stigmatic attitudes with seven large effect sizes (ranging from eta2 = .24 to .59) across the two measures. cit 0-3 DNA polymerase iota Homo sapiens 103-107 31354046-6 2019 PD-L1 status is predictive of CIT benefit and may assist patient selection and design of future trials. cit 30-33 CD274 molecule Homo sapiens 0-5 31052277-7 2019 Daily caloric intake was significantly higher in the target feeding than in the permissive underfeeding groups (P-value < 0.01), and the daily insulin dose was significantly higher in the IIT than in the CIT groups (P-value < 0.01). cit 207-210 insulin Homo sapiens 146-153 30419350-5 2019 Programmed cell death ligand-1 (PD-L1), which is a validated biomarker in non-small cell lung cancer (NSCLC), is often also used to select patients for CIT in the context of gastroesophageal cancer, although this marker has not been validated for this purpose. cit 152-155 CD274 molecule Homo sapiens 0-30 30764783-5 2019 CIT was identified based on: diagnosis code for thrombocytopenia or bleeding; procedure code for platelet transfusion or bleeding control; or drug code for thrombopoietin-receptor agonist. cit 0-3 MPL proto-oncogene, thrombopoietin receptor Homo sapiens 156-179 30419350-5 2019 Programmed cell death ligand-1 (PD-L1), which is a validated biomarker in non-small cell lung cancer (NSCLC), is often also used to select patients for CIT in the context of gastroesophageal cancer, although this marker has not been validated for this purpose. cit 152-155 CD274 molecule Homo sapiens 32-37 30419350-7 2019 This review discusses the value of PD-L1 in selecting patients for CIT in esophageal and gastric cancer. cit 67-70 CD274 molecule Homo sapiens 35-40 29997221-2 2018 With the availability of pathway inhibitors (PIs), such as kinase inhibitors and BCL2 antagonists, the outlook of CIT-resistant patients has dramatically improved. cit 114-117 BCL2 apoptosis regulator Homo sapiens 81-85 30563320-3 2019 Herein, we report a hypoxia-responsive mesoporous silica nanocarrier (denoted as CAGE) for an enhanced CIT assisted by photodynamic therapy (PDT). cit 103-106 DEAD-box helicase 53 Homo sapiens 81-85 30293399-3 2018 The main treatments of CIT include transfusion of platelets, recombinant human thrombopoietin (rhTPO), and recombinant human interleukin-11 (rhIL-11). cit 23-26 thrombopoietin Homo sapiens 79-93 30293399-3 2018 The main treatments of CIT include transfusion of platelets, recombinant human thrombopoietin (rhTPO), and recombinant human interleukin-11 (rhIL-11). cit 23-26 interleukin 11 Homo sapiens 125-139 30223836-10 2018 The application of the IBV nsp5 protein microarray showed that the positive rate of the CIT was 96.77%, that of the nsp5 ELISA was 91.40%, and that of the RDT was 90.32%. cit 88-91 sperm antigen with calponin homology and coiled-coil domains 1 Homo sapiens 27-31 30045972-16 2018 Finally, anti-cit-CRT Abs were preferentially detected in ACPA+ versus ACPA- RA sera. cit 14-17 proteinase 3 Homo sapiens 58-62 30045972-16 2018 Finally, anti-cit-CRT Abs were preferentially detected in ACPA+ versus ACPA- RA sera. cit 14-17 proteinase 3 Homo sapiens 71-75 29997221-4 2018 CLL high-risk-I, CIT-resistant is defined by clinically CIT-resistant disease with TP53 aberrations, but fully responsive to PI. cit 17-20 tumor protein p53 Homo sapiens 83-87 29997221-4 2018 CLL high-risk-I, CIT-resistant is defined by clinically CIT-resistant disease with TP53 aberrations, but fully responsive to PI. cit 56-59 tumor protein p53 Homo sapiens 83-87 30280609-5 2018 The IRE1alpha-XBP1 branch was activated at reperfusion only if CIT extended beyond 8 h, and had a dual role on cell fate - deleterious through IRE1"s RNase activity and beneficial through IRE1alpha other roles. cit 63-66 endoplasmic reticulum to nucleus signaling 1 Homo sapiens 4-8 30116746-3 2018 T1DM patients who partake in high-intensity aerobic training (AThigh) to reduce CVD often utilize conventional insulin therapy (CIT; 9-15 mmol/L) to offset the risk of hypoglycemia. cit 128-131 insulin Homo sapiens 111-118 29083483-6 2018 These findings suggest that collaborative encoding of crime-related information impacts the efficiency of the P300 index, and that the P300-based CIT is not applicable when used to identify collaborative crime perpetrators. cit 146-149 E1A binding protein p300 Homo sapiens 135-139 29375446-8 2017 After the antecedent emotional experience, the P300-based CIT was conducted. cit 58-61 E1A binding protein p300 Homo sapiens 47-51 29375446-11 2017 These results support the notion that emotional arousal influences the P300 in the CIT paradigm. cit 83-86 E1A binding protein p300 Homo sapiens 71-75 30280609-5 2018 The IRE1alpha-XBP1 branch was activated at reperfusion only if CIT extended beyond 8 h, and had a dual role on cell fate - deleterious through IRE1"s RNase activity and beneficial through IRE1alpha other roles. cit 63-66 endoplasmic reticulum to nucleus signaling 1 Homo sapiens 188-197 29480432-5 2018 Recent updates in CIT include that immunoglobulin heavy chain variable (IGHV) gene mutation status is strongly predictive of response to CIT. cit 18-21 immunoglobulin heavy variable 3-69-1 (pseudogene) Homo sapiens 35-77 29480432-5 2018 Recent updates in CIT include that immunoglobulin heavy chain variable (IGHV) gene mutation status is strongly predictive of response to CIT. cit 137-140 immunoglobulin heavy variable 3-69-1 (pseudogene) Homo sapiens 35-77 30280609-5 2018 The IRE1alpha-XBP1 branch was activated at reperfusion only if CIT extended beyond 8 h, and had a dual role on cell fate - deleterious through IRE1"s RNase activity and beneficial through IRE1alpha other roles. cit 63-66 endoplasmic reticulum to nucleus signaling 1 Homo sapiens 4-13 30280609-6 2018 Finally, the pro-apoptotic factor CHOP was a common target of both ATF6 and IRE1alpha pathways and was associated with elongated CIT and increased cell death. cit 129-132 DNA damage inducible transcript 3 Homo sapiens 34-38 28450306-7 2017 Importantly, we found that low doses of IL-9 efficiently prevented chemotherapy-induced thrombocytopenia (CIT) and accelerated platelet recovery after CIT. cit 106-109 interleukin 9 Mus musculus 40-44 30280609-6 2018 Finally, the pro-apoptotic factor CHOP was a common target of both ATF6 and IRE1alpha pathways and was associated with elongated CIT and increased cell death. cit 129-132 activating transcription factor 6 Homo sapiens 67-71 30280609-6 2018 Finally, the pro-apoptotic factor CHOP was a common target of both ATF6 and IRE1alpha pathways and was associated with elongated CIT and increased cell death. cit 129-132 endoplasmic reticulum to nucleus signaling 1 Homo sapiens 76-85 30280609-5 2018 The IRE1alpha-XBP1 branch was activated at reperfusion only if CIT extended beyond 8 h, and had a dual role on cell fate - deleterious through IRE1"s RNase activity and beneficial through IRE1alpha other roles. cit 63-66 X-box binding protein 1 Homo sapiens 14-18 28589701-2 2017 One such predictive biomarker is the mutational status of the variable region of the immunoglobulin heavy chain (IGHV) gene, which is a powerful predictor of duration of response and overall survival with chemoimmunotherapy (CIT). cit 225-228 immunoglobulin heavy variable 3/OR16-7 (pseudogene) Homo sapiens 85-111 28589701-2 2017 One such predictive biomarker is the mutational status of the variable region of the immunoglobulin heavy chain (IGHV) gene, which is a powerful predictor of duration of response and overall survival with chemoimmunotherapy (CIT). cit 225-228 immunoglobulin heavy variable 3/OR16-7 (pseudogene) Homo sapiens 113-117 28450306-7 2017 Importantly, we found that low doses of IL-9 efficiently prevented chemotherapy-induced thrombocytopenia (CIT) and accelerated platelet recovery after CIT. cit 151-154 interleukin 9 Mus musculus 40-44 28450306-8 2017 These data indicate that IL-9 is an essential regulator of megakaryopoiesis and a promising therapeutic agent for treatment of thrombocytopenia such as CIT. cit 152-155 interleukin 9 Mus musculus 25-29 27420293-11 2016 CONCLUSION: An increased CIMT by aging was mainly due to increased CMT rather than CIT in asymptomatic adults. cit 83-86 CIMT Homo sapiens 25-29 27906052-11 2016 However, association was observed between the PTPN22 risk allele and positivity to cit-Fib alpha-35 and cit-Fib alpha-263,271. cit 83-86 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 46-52 27906052-11 2016 However, association was observed between the PTPN22 risk allele and positivity to cit-Fib alpha-35 and cit-Fib alpha-263,271. cit 83-86 fibrinogen beta chain Homo sapiens 87-90 27322064-9 2016 Importantly, the Causal Inference Test (CIT) demonstrates how genetic variants mediate their effects on metabolic traits (e.g. BMI, cholesterol, high-density lipoprotein (HDL), hemoglobin A1c (HbA1c) and homeostatic model assessment of insulin resistance (HOMA-IR)) via altered DNA methylation in human adipose tissue. cit 40-43 insulin Homo sapiens 236-243 27055777-14 2016 Some new IgG- and IgA-ACPA, generally to different Cit-antigens however, arose at Relapse in 4 patients. cit 51-54 proteinase 3 Homo sapiens 22-26 26236025-7 2015 In CIT-exposed rats binding to N-methyl-D-aspartate (NMDA) receptors containing the GluN2B subunit, as determined using [(3)H]-ifenprodil, was decreased in a concentration-related manner in the caudal cingulate cortex, dorsal striatum and accumbens; however, this was not associated with changes in GluN2B protein expression. cit 3-6 glutamate ionotropic receptor NMDA type subunit 2B Rattus norvegicus 84-90 25825261-2 2016 We evaluated the risk of DSWI and other clinical outcomes between continuous insulin infusion therapy (CIT) and insulin sliding scale therapy (IST) in a cohort of DM patients who underwent CABG with BIMA. cit 103-106 insulin Homo sapiens 77-84 26925632-1 2016 OBJECTIVE: to investigate the effect and side effects of recombinant human interleukin - 11 (rhIL - 11, in Chinese Juheli, produced by Qi Lu Biotechnology CO., LTD) in the second prevention of chemotherapy induced thrombocytopenia (CIT). cit 232-235 interleukin 11 Homo sapiens 75-91 26236025-7 2015 In CIT-exposed rats binding to N-methyl-D-aspartate (NMDA) receptors containing the GluN2B subunit, as determined using [(3)H]-ifenprodil, was decreased in a concentration-related manner in the caudal cingulate cortex, dorsal striatum and accumbens; however, this was not associated with changes in GluN2B protein expression. cit 3-6 glutamate ionotropic receptor NMDA type subunit 2B Rattus norvegicus 299-305 25838088-9 2015 mPIS values of subjects requiring continuous inhalation therapy (CIT) with isoproterenol in addition to systemic steroids were significantly higher than the values of those without CIT (12.0 +- 0.5 and 9.3 +- 0.2, respectively, p < 0.001). cit 65-68 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) Mus musculus 0-4 26337028-5 2015 Serum RANKL (total RANKL), ACPA (anti-CCP2) and ACPA specificities (anti-citrullinated (cit)-vimentin, anti-cit-enolase and anti-cit-fibrinogen) were determined by enzyme-linked immunosorbent assay (ELISA). cit 60-63 TNF superfamily member 11 Homo sapiens 6-11 26337028-5 2015 Serum RANKL (total RANKL), ACPA (anti-CCP2) and ACPA specificities (anti-citrullinated (cit)-vimentin, anti-cit-enolase and anti-cit-fibrinogen) were determined by enzyme-linked immunosorbent assay (ELISA). cit 60-63 proteinase 3 Homo sapiens 48-52 26337028-11 2015 Among ACPA specificites, anti-cit-vimentin (amino acids 60-75) was associated with higher RANKL concentration and higher prevalence of bone erosion (p <0.05). cit 18-21 proteinase 3 Homo sapiens 6-10 26337028-11 2015 Among ACPA specificites, anti-cit-vimentin (amino acids 60-75) was associated with higher RANKL concentration and higher prevalence of bone erosion (p <0.05). cit 18-21 vimentin Homo sapiens 34-42 25899003-5 2015 We reproducibly associate higher expression of the ligand-receptor axis of TFF2 and CXCR4 with BRAF V600E-mutant colon cancer (P = 3.0 x 10(-3) and 0.077, respectively for TCGA; P = 3.0 x 10(-8) and 5.1 x 10(-7) for CIT). cit 216-219 trefoil factor 2 Homo sapiens 75-79 26337028-13 2015 CONCLUSIONS: RANKL was elevated in ACPA-positive and in anti-cit-vimentin-positive patients with early untreated RA and associated with bone erosions. cit 61-64 TNF superfamily member 11 Homo sapiens 13-18 26337028-13 2015 CONCLUSIONS: RANKL was elevated in ACPA-positive and in anti-cit-vimentin-positive patients with early untreated RA and associated with bone erosions. cit 61-64 vimentin Homo sapiens 65-73 25428389-2 2015 In this paper, I discussed the effect of ABO blood group on CIT in patients with stage III colon cancer. cit 60-63 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Homo sapiens 41-56 25729723-8 2015 CONCLUSIONS: Combined use of the MHT and CIT with PBA and EDTA, for the detection of CPE and MBL-producing Pseudomonas spp., is effective in detecting and characterizing carbapenemases in routine laboratories. cit 41-44 hypothetical protein Klebsiella pneumoniae 93-96 25405287-10 2014 In addition, the CIT administration also significantly enhanced the OPG expression, whereas reduced the RANKL expression in femurs according to RT-PCR, western blot assays and immunohistochemical evaluation. cit 17-20 TNF receptor superfamily member 11B Rattus norvegicus 68-71 25405287-10 2014 In addition, the CIT administration also significantly enhanced the OPG expression, whereas reduced the RANKL expression in femurs according to RT-PCR, western blot assays and immunohistochemical evaluation. cit 17-20 TNF superfamily member 11 Rattus norvegicus 104-109 22507801-2 2012 Chemoimmunotherapy (CIT) combining anti-CD20 monoclonal antibodies with purine nucleoside analogs has been a substantial advance for patients with CLL and results in increased response rates, progression-free survival, and overall survival. cit 20-23 keratin 20 Homo sapiens 40-44 23490488-1 2014 BACKGROUND AND OBJECTIVE: Recent studies in critically ill patients receiving insulin intravenous therapy (IIT) have shown an increased incidence of severe hypoglycemia, while intermittent subcutaneous insulin <<sliding scales>> (conventional insulin therapy [CIT]) is associated with hyperglycemia. cit 272-275 insulin Homo sapiens 78-85 23490488-1 2014 BACKGROUND AND OBJECTIVE: Recent studies in critically ill patients receiving insulin intravenous therapy (IIT) have shown an increased incidence of severe hypoglycemia, while intermittent subcutaneous insulin <<sliding scales>> (conventional insulin therapy [CIT]) is associated with hyperglycemia. cit 272-275 insulin Homo sapiens 202-209 23490488-1 2014 BACKGROUND AND OBJECTIVE: Recent studies in critically ill patients receiving insulin intravenous therapy (IIT) have shown an increased incidence of severe hypoglycemia, while intermittent subcutaneous insulin <<sliding scales>> (conventional insulin therapy [CIT]) is associated with hyperglycemia. cit 272-275 insulin Homo sapiens 202-209 23543349-5 2013 Citrullinated (Cit) and native peptides of Vimentin and Aggrecan were used for stimulating peripheral blood mononuclear cells in 5-day cultures. cit 0-3 vimentin Homo sapiens 43-51 23256681-10 2013 EXPERT OPINION: Rituximab, the prototype anti-CD20 mAb, forms the core of CIT in CLL. cit 74-77 keratin 20 Homo sapiens 46-50 23150685-3 2013 OBJECTIVE: Our objective was to evaluate the effects of mild cold exposure on circulating FGF21 and its relationship with CIT and lipolysis in humans. cit 122-125 fibroblast growth factor 21 Homo sapiens 90-95 23150685-12 2013 CONCLUSIONS: Mild cold exposure increased circulating FGF21 levels, predicting greater lipolysis and CIT. cit 101-104 fibroblast growth factor 21 Homo sapiens 54-59 21632816-9 2011 RESULTS: On d 3, C-peptide was more than 10-fold lower (P < 0.0001) in the IIT group than in the CIT group. cit 100-103 insulin Homo sapiens 17-26 22114740-5 2012 Using variables of ACS symptoms we estimated the likelihood of ACS based on a CIT to be high at 91% (32), low at 4% (198) and intermediate at 20.5-40% in (71) patients. cit 78-81 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Homo sapiens 63-66 21907557-1 2011 Chrono-impedance technique (CIT) was implemented as a new transduction method for real time measurement of glucose in a biosensor system based in carbon paste (CP)/Ferrocene (FC)/glucose oxidase (GOx). cit 28-31 hydroxyacid oxidase 1 Homo sapiens 196-199 22071938-2 2011 In the present study, we performed a meta-analysis of literature comparing the efficacy and safety of IIT and conventional insulin therapy (CIT) for critically ill neurologic patients in terms of mortality, infection rate, neurologic outcome, and hypoglycemia. cit 140-143 insulin Homo sapiens 123-130 21609374-6 2011 RESULTS: In 22 CDD organ transplants, CIT was a strong predictor of PNF or IC (P = 0.021). cit 38-41 natriuretic peptide A Homo sapiens 15-18 21683135-10 2011 In addition, CIT increased CRF-R2 gene expression in the dorsal raphe. cit 13-16 corticotropin releasing hormone receptor 2 Homo sapiens 27-33 21609374-7 2011 Minimising CIT in CDD organ transplants produced outcomes similar to those in a matched SCD organ transplant cohort at our centre and in SCD organ transplant results nationally (1- and 3-year graft and patient survival rates: 90.9% and 73.3% vs. 77.6% and 69.2% in CDD and SCD grafts, respectively. cit 11-14 natriuretic peptide A Homo sapiens 18-21 21609374-7 2011 Minimising CIT in CDD organ transplants produced outcomes similar to those in a matched SCD organ transplant cohort at our centre and in SCD organ transplant results nationally (1- and 3-year graft and patient survival rates: 90.9% and 73.3% vs. 77.6% and 69.2% in CDD and SCD grafts, respectively. cit 11-14 natriuretic peptide A Homo sapiens 265-268 21609374-9 2011 CONCLUSIONS: These findings suggest that a targeted effort to minimise CIT might improve outcomes and allow the safer use of CDD organs. cit 71-74 natriuretic peptide A Homo sapiens 125-128