PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 15145798-12 2004 The final network yields an overall accuracy of 74.5, 93.5, 67.9 and 96.5% with MCC values of 0.29, 0.29, 0.23 and 0.02 for Type I, II, IV and VIII beta-turns, respectively, and is better than random prediction. mcc 80-83 cytochrome c oxidase subunit 8A Homo sapiens 143-147 16115476-7 2005 Transient transfection of bovine aortic ECs with a VCAM-1 promoter construct revealed that MCC-555 inhibited TNF-alpha-induced VCAM-1 promoter activity. mcc 91-94 vascular cell adhesion molecule 1 Bos taurus 51-57 16115476-7 2005 Transient transfection of bovine aortic ECs with a VCAM-1 promoter construct revealed that MCC-555 inhibited TNF-alpha-induced VCAM-1 promoter activity. mcc 91-94 tumor necrosis factor Bos taurus 109-118 16115476-7 2005 Transient transfection of bovine aortic ECs with a VCAM-1 promoter construct revealed that MCC-555 inhibited TNF-alpha-induced VCAM-1 promoter activity. mcc 91-94 vascular cell adhesion molecule 1 Bos taurus 127-133 28017606-4 2017 MCC formation inhibits the anaphase-promoting complex/cyclosome (Cdc20-APC/C), thereby preventing the proteolytic destruction of securin and cyclin and delaying anaphase onset. mcc 0-3 cell division cycle 20 Homo sapiens 65-70 9888462-5 1999 We have found that, although MCC is a potent inducer of IL-12 and IL-6 synthesis in monocytes and macrophages either in vitro or in vivo, it is unable to induce the synthesis of either IL-12, IL-6 or granulocyte-macrophage colony-stimulating factor (GM-CSF) by the human transitional bladder cancer cell lines HT-1197 and HT-1376. mcc 29-32 interleukin 6 Homo sapiens 66-70 34342085-3 2021 The aim was to investigate the effects of NF-kappaB/HIF-2alpha on MCC degradation induced by mechanical stress, and the regulatory mechanism of NF-kappaB in the HIF-2alpha pathway. mcc 66-69 nuclear factor kappa B subunit 1 Homo sapiens 42-51 34342085-3 2021 The aim was to investigate the effects of NF-kappaB/HIF-2alpha on MCC degradation induced by mechanical stress, and the regulatory mechanism of NF-kappaB in the HIF-2alpha pathway. mcc 66-69 endothelial PAS domain protein 1 Homo sapiens 52-62 34342085-3 2021 The aim was to investigate the effects of NF-kappaB/HIF-2alpha on MCC degradation induced by mechanical stress, and the regulatory mechanism of NF-kappaB in the HIF-2alpha pathway. mcc 66-69 nuclear factor kappa B subunit 1 Homo sapiens 144-153 34342085-3 2021 The aim was to investigate the effects of NF-kappaB/HIF-2alpha on MCC degradation induced by mechanical stress, and the regulatory mechanism of NF-kappaB in the HIF-2alpha pathway. mcc 66-69 endothelial PAS domain protein 1 Homo sapiens 161-171 31459971-9 2019 We determined four forms of unconjugated linkers: (N-maleimidomethyl) cyclohexane-1-carboxylate (MCC) unconjugated to DM1, hydrolyzed MCC unconjugated to DM1, lys-MCC-lys, and lys-MCC-cys. mcc 97-100 immunoglobulin heavy diversity 1-7 Homo sapiens 118-121 28927065-9 2017 Zymography was used to examine the effects of MCC on the expression and activation of matrix metalloproteinase-9 (MMP-9) in A549 and H520 cells. mcc 46-49 matrix metallopeptidase 9 Homo sapiens 86-112 28927065-9 2017 Zymography was used to examine the effects of MCC on the expression and activation of matrix metalloproteinase-9 (MMP-9) in A549 and H520 cells. mcc 46-49 matrix metallopeptidase 9 Homo sapiens 114-119 28366744-10 2017 MCC binding to the second molecule of Cdc20 is mediated via the C-terminal KEN box in Mad3. mcc 0-3 ubiquitin-protein transferase activating protein CDC20 Saccharomyces cerevisiae S288C 38-43 28017606-4 2017 MCC formation inhibits the anaphase-promoting complex/cyclosome (Cdc20-APC/C), thereby preventing the proteolytic destruction of securin and cyclin and delaying anaphase onset. mcc 0-3 PTTG1 regulator of sister chromatid separation, securin Homo sapiens 129-136 28017606-4 2017 MCC formation inhibits the anaphase-promoting complex/cyclosome (Cdc20-APC/C), thereby preventing the proteolytic destruction of securin and cyclin and delaying anaphase onset. mcc 0-3 proliferating cell nuclear antigen Homo sapiens 141-147 25598413-5 2015 In mouse tracheal epithelial cells, mab21-l3 expression is also downregulated by the Notch pathway and is required for MCC differentiation. mcc 119-122 mab-21-like 3 Mus musculus 36-44 26947080-6 2016 In summary, p73 is essential for MCC differentiation, functions as a critical regulator of a transcriptome required for MCC differentiation, and, like p63, has an essential role in development of tissues. mcc 33-36 transformation related protein 73 Mus musculus 12-15 26947080-6 2016 In summary, p73 is essential for MCC differentiation, functions as a critical regulator of a transcriptome required for MCC differentiation, and, like p63, has an essential role in development of tissues. mcc 120-123 transformation related protein 73 Mus musculus 12-15 24803518-2 2014 McC is synthesized by the MccB enzyme, which terminally adenylates the ribosomally synthesized heptapeptide precursor MccA. mcc 0-3 MccB Escherichia coli 26-30 24761124-12 2014 CONCLUSION: These studies showed that MCC and MTI have both hypoglycemic and antioxidant potential but MCC is more potent than MTI. mcc 38-41 metallothionein 1 Mus musculus 127-130 24761124-12 2014 CONCLUSION: These studies showed that MCC and MTI have both hypoglycemic and antioxidant potential but MCC is more potent than MTI. mcc 103-106 metallothionein 1 Mus musculus 46-49