PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
29371085-1	2018	(E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a new (E)-2,4-bis(p-hydroxyphenyl)-2 - butenal derivative, reportedly has therapeutic effects such as anti-arthritic properties.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	61-65	PROP paired-like homeobox 1	Homo sapiens	37-43
31146332-7	2019	Increased activation of STAT3, p38, and monoamine oxidase B (MAO-B) were observed in the substantia nigra and striatum after MPTP injection, effects that were attenuated by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	173-177	signal transducer and activator of transcription 3	Mus musculus	24-29
31146332-7	2019	Increased activation of STAT3, p38, and monoamine oxidase B (MAO-B) were observed in the substantia nigra and striatum after MPTP injection, effects that were attenuated by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	173-177	mitogen-activated protein kinase 14	Mus musculus	31-34
31146332-7	2019	Increased activation of STAT3, p38, and monoamine oxidase B (MAO-B) were observed in the substantia nigra and striatum after MPTP injection, effects that were attenuated by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	173-177	monoamine oxidase B	Mus musculus	40-59
31146332-7	2019	Increased activation of STAT3, p38, and monoamine oxidase B (MAO-B) were observed in the substantia nigra and striatum after MPTP injection, effects that were attenuated by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	173-177	monoamine oxidase B	Mus musculus	61-66
31146332-8	2019	Furthermore, MMPP inhibited STAT3 activity and expression of neuroinflammatory proteins, including ionized calcium binding adaptor molecule 1 (Iba1), inducible nitric oxide synthase (iNOS), and glial fibrillary acidic protein (GFAP) in 1-methyl-4-phenylpyridinium (MPP+; 0.5 mM)-treated primary cultured cells.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	13-17	signal transducer and activator of transcription 3	Mus musculus	28-33
31146332-8	2019	Furthermore, MMPP inhibited STAT3 activity and expression of neuroinflammatory proteins, including ionized calcium binding adaptor molecule 1 (Iba1), inducible nitric oxide synthase (iNOS), and glial fibrillary acidic protein (GFAP) in 1-methyl-4-phenylpyridinium (MPP+; 0.5 mM)-treated primary cultured cells.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	13-17	nitric oxide synthase 2, inducible	Mus musculus	150-181
31146332-8	2019	Furthermore, MMPP inhibited STAT3 activity and expression of neuroinflammatory proteins, including ionized calcium binding adaptor molecule 1 (Iba1), inducible nitric oxide synthase (iNOS), and glial fibrillary acidic protein (GFAP) in 1-methyl-4-phenylpyridinium (MPP+; 0.5 mM)-treated primary cultured cells.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	13-17	nitric oxide synthase 2, inducible	Mus musculus	183-187
31146332-8	2019	Furthermore, MMPP inhibited STAT3 activity and expression of neuroinflammatory proteins, including ionized calcium binding adaptor molecule 1 (Iba1), inducible nitric oxide synthase (iNOS), and glial fibrillary acidic protein (GFAP) in 1-methyl-4-phenylpyridinium (MPP+; 0.5 mM)-treated primary cultured cells.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	13-17	glial fibrillary acidic protein	Mus musculus	194-225
31146332-8	2019	Furthermore, MMPP inhibited STAT3 activity and expression of neuroinflammatory proteins, including ionized calcium binding adaptor molecule 1 (Iba1), inducible nitric oxide synthase (iNOS), and glial fibrillary acidic protein (GFAP) in 1-methyl-4-phenylpyridinium (MPP+; 0.5 mM)-treated primary cultured cells.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	13-17	glial fibrillary acidic protein	Mus musculus	227-231
31146332-10	2019	Collectively, our results suggest that MMPP may be an anti-inflammatory agent that attenuates dopaminergic neurodegeneration and neuroinflammation through MAO-B and MAPK pathway-dependent inhibition of STAT3 activation.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	39-43	monoamine oxidase B	Mus musculus	155-160
31146332-10	2019	Collectively, our results suggest that MMPP may be an anti-inflammatory agent that attenuates dopaminergic neurodegeneration and neuroinflammation through MAO-B and MAPK pathway-dependent inhibition of STAT3 activation.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	39-43	signal transducer and activator of transcription 3	Mus musculus	202-207
31146332-2	2019	We have previously demonstrated that (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a selective signal transducer and activator of transcription 3 (STAT3) inhibitor, has anti-inflammatory properties in several inflammatory disease models.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	98-102	paired like homeodomain factor 1	Mus musculus	74-80
31146332-2	2019	We have previously demonstrated that (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a selective signal transducer and activator of transcription 3 (STAT3) inhibitor, has anti-inflammatory properties in several inflammatory disease models.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	98-102	signal transducer and activator of transcription 3	Mus musculus	117-167
31146332-2	2019	We have previously demonstrated that (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a selective signal transducer and activator of transcription 3 (STAT3) inhibitor, has anti-inflammatory properties in several inflammatory disease models.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	98-102	signal transducer and activator of transcription 3	Mus musculus	169-174
29371085-6	2018	MMPP inhibited PMA-induced membrane translocation of PKCdelta, phosphorylation of JNK, and nuclear translocation of AP-1, resulting in downregulation of cyclooxygenase-2 and chemokine ligand 5 production.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	protein kinase C delta	Homo sapiens	53-61
29371085-6	2018	MMPP inhibited PMA-induced membrane translocation of PKCdelta, phosphorylation of JNK, and nuclear translocation of AP-1, resulting in downregulation of cyclooxygenase-2 and chemokine ligand 5 production.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	mitogen-activated protein kinase 8	Homo sapiens	82-85
29371085-6	2018	MMPP inhibited PMA-induced membrane translocation of PKCdelta, phosphorylation of JNK, and nuclear translocation of AP-1, resulting in downregulation of cyclooxygenase-2 and chemokine ligand 5 production.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	116-120
29371085-6	2018	MMPP inhibited PMA-induced membrane translocation of PKCdelta, phosphorylation of JNK, and nuclear translocation of AP-1, resulting in downregulation of cyclooxygenase-2 and chemokine ligand 5 production.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	prostaglandin-endoperoxide synthase 2	Homo sapiens	153-169
29371085-7	2018	These findings indicate that MMPP inhibits inflammatory responses in THP-1 cells by mitigating PMA-induced activation of PKCdelta and JNK and nuclear translocation of AP-1.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	29-33	protein kinase C delta	Homo sapiens	121-129
29371085-7	2018	These findings indicate that MMPP inhibits inflammatory responses in THP-1 cells by mitigating PMA-induced activation of PKCdelta and JNK and nuclear translocation of AP-1.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	29-33	mitogen-activated protein kinase 8	Homo sapiens	134-137
29158850-0	2017	MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	signal transducer and activator of transcription 3	Homo sapiens	68-73
29371085-7	2018	These findings indicate that MMPP inhibits inflammatory responses in THP-1 cells by mitigating PMA-induced activation of PKCdelta and JNK and nuclear translocation of AP-1.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	29-33	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	167-171
29052076-9	2017	Moreover, MMPP treatment suppressed DNA binding activities of the activation of STAT3 in in vivo and in vitro.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	10-14	signal transducer and activator of transcription 3	Mus musculus	80-85
29052076-10	2017	These results indicated that MMPP inhibits LPS-induced amyloidogenesis and neuroinflammation via inhibition of STAT3.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	29-33	signal transducer and activator of transcription 3	Mus musculus	111-116
29158850-0	2017	MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	signal transducer and activator of transcription 3	Homo sapiens	121-126
29158850-4	2017	Methods: We demonstrated the potential antitumor activity of a novel, small-molecule (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) that directly binds to the DBD of STAT3, in patient-derived non-small cell lung cancer (NSCLC) xenograft model as well as in NCI-H460 cell xenograft model in nude mice.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	144-148	signal transducer and activator of transcription 3	Homo sapiens	184-189
29158850-5	2017	Results: MMPP effectively inhibited the phosphorylation of STAT3 and its DNA binding activity in vitro and in vivo.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	9-13	signal transducer and activator of transcription 3	Homo sapiens	59-64
29158850-8	2017	Conclusion: MMPP is suggested to be a potential candidate for further development as an anticancer drug that targets the DBD of STAT3.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	12-16	signal transducer and activator of transcription 3	Homo sapiens	128-133
28277616-2	2017	Interestingly, among the 16 compounds, we found that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) showed the most significant anti-proliferative effect on PA-1 and SK-OV-3 ovarian epithelial cancer cells.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	112-116	PROP paired-like homeobox 1	Homo sapiens	89-95
28277616-3	2017	MMPP treatment (0-15 microg/mL) induced apoptotic cell death, enhanced the expression of cleaved caspase-3, and cleaved caspase-9 in a concentration dependent manner.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	caspase 3	Homo sapiens	97-106
28277616-3	2017	MMPP treatment (0-15 microg/mL) induced apoptotic cell death, enhanced the expression of cleaved caspase-3, and cleaved caspase-9 in a concentration dependent manner.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	caspase 9	Homo sapiens	120-129
28277616-4	2017	Notably, DNA binding activity of STAT3, phosphorylation of extracellular signal-regulated kinase (ERK) and p38 was significantly decreased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	142-146	signal transducer and activator of transcription 3	Homo sapiens	33-38
28277616-4	2017	Notably, DNA binding activity of STAT3, phosphorylation of extracellular signal-regulated kinase (ERK) and p38 was significantly decreased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	142-146	mitogen-activated protein kinase 1	Homo sapiens	59-96
28277616-4	2017	Notably, DNA binding activity of STAT3, phosphorylation of extracellular signal-regulated kinase (ERK) and p38 was significantly decreased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	142-146	mitogen-activated protein kinase 1	Homo sapiens	98-101
28277616-4	2017	Notably, DNA binding activity of STAT3, phosphorylation of extracellular signal-regulated kinase (ERK) and p38 was significantly decreased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	142-146	mitogen-activated protein kinase 1	Homo sapiens	107-110
28277616-5	2017	However, ERK siRNA augmented MMPP-induced inhibitory effect on cell growth rather than p38 siRNA or JNK siRNA.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	29-33	mitogen-activated protein kinase 1	Homo sapiens	9-12
28277616-6	2017	Moreover, combination treatment of MMPP with ERK inhibitor U0126 (10 microM) augmented MMPP-induced inhibitory effect on cell growth and DNA binding activity of STAT3, and enhanced expression of cleaved caspase-3 and cleaved caspase-9.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	35-39	mitogen-activated protein kinase 1	Homo sapiens	45-48
28277616-6	2017	Moreover, combination treatment of MMPP with ERK inhibitor U0126 (10 microM) augmented MMPP-induced inhibitory effect on cell growth and DNA binding activity of STAT3, and enhanced expression of cleaved caspase-3 and cleaved caspase-9.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	35-39	signal transducer and activator of transcription 3	Homo sapiens	161-166
28277616-6	2017	Moreover, combination treatment of MMPP with ERK inhibitor U0126 (10 microM) augmented MMPP-induced inhibitory effect on cell growth and DNA binding activity of STAT3, and enhanced expression of cleaved caspase-3 and cleaved caspase-9.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	35-39	caspase 3	Homo sapiens	203-212
28277616-6	2017	Moreover, combination treatment of MMPP with ERK inhibitor U0126 (10 microM) augmented MMPP-induced inhibitory effect on cell growth and DNA binding activity of STAT3, and enhanced expression of cleaved caspase-3 and cleaved caspase-9.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	35-39	caspase 9	Homo sapiens	225-234
28277616-6	2017	Moreover, combination treatment of MMPP with ERK inhibitor U0126 (10 microM) augmented MMPP-induced inhibitory effect on cell growth and DNA binding activity of STAT3, and enhanced expression of cleaved caspase-3 and cleaved caspase-9.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	87-91	mitogen-activated protein kinase 1	Homo sapiens	45-48
28277616-6	2017	Moreover, combination treatment of MMPP with ERK inhibitor U0126 (10 microM) augmented MMPP-induced inhibitory effect on cell growth and DNA binding activity of STAT3, and enhanced expression of cleaved caspase-3 and cleaved caspase-9.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	87-91	signal transducer and activator of transcription 3	Homo sapiens	161-166
28277616-6	2017	Moreover, combination treatment of MMPP with ERK inhibitor U0126 (10 microM) augmented MMPP-induced inhibitory effect on cell growth and DNA binding activity of STAT3, and enhanced expression of cleaved caspase-3 and cleaved caspase-9.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	87-91	caspase 9	Homo sapiens	225-234
28277616-7	2017	In addition, STAT3 siRNA transfection augmented MMPP-induced cell growth inhibition.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	48-52	signal transducer and activator of transcription 3	Homo sapiens	13-18
28277616-9	2017	Immunohistochemistry staining showed that the expression levels of p-ERK, PCNA, p-STAT3 were decreased while the expression level of caspase-3 was increased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	160-164	eukaryotic translation initiation factor 2 alpha kinase 3	Homo sapiens	67-72
28277616-9	2017	Immunohistochemistry staining showed that the expression levels of p-ERK, PCNA, p-STAT3 were decreased while the expression level of caspase-3 was increased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	160-164	proliferating cell nuclear antigen	Homo sapiens	74-78
28277616-9	2017	Immunohistochemistry staining showed that the expression levels of p-ERK, PCNA, p-STAT3 were decreased while the expression level of caspase-3 was increased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	160-164	signal transducer and activator of transcription 3	Homo sapiens	82-87
28277616-9	2017	Immunohistochemistry staining showed that the expression levels of p-ERK, PCNA, p-STAT3 were decreased while the expression level of caspase-3 was increased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	160-164	caspase 3	Homo sapiens	133-142
29207641-1	2017	Here we report that a novel synthesized compound (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) which exhibits better stability, drug-likeness and anti-cancer effect than (E)-2,4-bis(p-hydroxyphenyl)-2-butenal (BHPB) that we previously reported.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	108-112	paired like homeodomain factor 1	Mus musculus	85-91
29207641-4	2017	MMPP treatment (0-15 mug/mL) induced apoptotic cell death and enhanced the expression of cleaved caspase-3 and cleaved caspase-8 in a concentration dependent manner.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	caspase 3	Mus musculus	97-106
29207641-4	2017	MMPP treatment (0-15 mug/mL) induced apoptotic cell death and enhanced the expression of cleaved caspase-3 and cleaved caspase-8 in a concentration dependent manner.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	0-4	caspase 8	Mus musculus	119-128
29207641-5	2017	Notably, the expression of death receptor (DR)5 and DR6 was significantly increased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	87-91	tumor necrosis factor receptor superfamily, member 10b	Mus musculus	27-47
29207641-5	2017	Notably, the expression of death receptor (DR)5 and DR6 was significantly increased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	87-91	tumor necrosis factor receptor superfamily, member 21	Mus musculus	52-55
29207641-6	2017	Moreover, DR5 siRNA or DR6 siRNA transfection partially abolished MMPP-induced cell growth inhibition.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	66-70	tumor necrosis factor receptor superfamily, member 10b	Mus musculus	10-13
29207641-6	2017	Moreover, DR5 siRNA or DR6 siRNA transfection partially abolished MMPP-induced cell growth inhibition.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	66-70	tumor necrosis factor receptor superfamily, member 21	Mus musculus	23-26
29207641-7	2017	Pull down assay and docking experiment showed that MMPP bound directly to IkappaB kinase beta (IKKbeta).	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	51-55	inhibitor of kappaB kinase beta	Mus musculus	74-93
29207641-7	2017	Pull down assay and docking experiment showed that MMPP bound directly to IkappaB kinase beta (IKKbeta).	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	51-55	inhibitor of kappaB kinase beta	Mus musculus	95-102
29207641-8	2017	It was noteworthy that IKKbeta mutant (C99S) partially abolished MMPP-induced cell growth inhibition and enhanced expression of DR5 and DR6.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	65-69	inhibitor of kappaB kinase beta	Mus musculus	23-30
29207641-8	2017	It was noteworthy that IKKbeta mutant (C99S) partially abolished MMPP-induced cell growth inhibition and enhanced expression of DR5 and DR6.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	65-69	tumor necrosis factor receptor superfamily, member 10b	Mus musculus	128-131
29207641-8	2017	It was noteworthy that IKKbeta mutant (C99S) partially abolished MMPP-induced cell growth inhibition and enhanced expression of DR5 and DR6.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	65-69	tumor necrosis factor receptor superfamily, member 21	Mus musculus	136-139
29207641-9	2017	In addition, MMPP enhanced TRAIL-induced apoptosis, cell growth inhibition and expression of DRs.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	13-17	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	27-32
27845373-5	2016	We designed and synthesised (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a novel synthetic BHPB analogue, and investigated its anti-inflammatory and anti-arthritic activities in experimentally-induced RA.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	89-93	PROP paired-like homeobox 1	Homo sapiens	65-71
28511296-1	2017	(E)-2-Methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP), derived from butenal, is a recently synthesized Maillard reaction product.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	59-63	PROP paired-like homeobox 1	Homo sapiens	36-42
28511296-4	2017	We observed that MMPP was cytotoxic to HeLa cells and induced activation of caspase-3, -8, and -9, without affecting the expression of the viral oncogenes E6 and E7.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	17-21	caspase 3	Homo sapiens	76-97
28511296-5	2017	In particular, the expression of the death receptors DR5 and FAS was significantly increased by MMPP treatment.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	96-100	TNF receptor superfamily member 10b	Homo sapiens	53-56
27845373-6	2016	We showed that MMPP strongly inhibited pro-inflammatory responses by inhibiting in vitro STAT3 activation and its downstream signalling in murine macrophages and human synoviocytes from patients with RA.	2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol	15-19	signal transducer and activator of transcription 3	Mus musculus	89-94