PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
8804068-2	1996	EC 33 (3-amino-4-thio-butyl sulfonate), a selective APA inhibitor, decreased the formation of CCK7 after incubation of CCK-8 with rat brain synaptic membranes.	ec	0-2	glutamyl aminopeptidase	Rattus norvegicus	52-55
7960462-3	1994	At rest with EC, the only significant variation was an increase of beta 1 relative power in old subjects which was positively correlated with age.	ec	13-15	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	67-73
8659090-8	1995	The average value of G-6-PD activity was 13.96 +/- 0.94 mU.10 (-9) Ec in control animals and 14.39 +/- 1.49 mU.10 (-9) Ec in the animals from a contaminated region.	ec	67-69	glucose-6-phosphate 1-dehydrogenase	Ovis aries	21-27
7937837-1	1994	A mutant of Escherichia coli, JTG10, deficient in gamma-glutamylcysteine synthetase (gamma-ECS; EC 6.3.2.2) is unable to synthesize glutathione (GSH) and is sensitive to 8-hydroxyquinoline.	ec	91-93	glutamate-cysteine ligase catalytic subunit	Homo sapiens	50-83
23606003-3	1992	TSS1 had stronger antibiotic activity againstEscherichia coli (EC 50: 10mug/mL) than rosenonolactone (EC 50: >200mug/mL) but weaker activity than trichothecin (EC 50: 3mug/mL).	ec	63-65	alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1	Saccharomyces cerevisiae S288C	0-4
8200410-5	1994	Using these combined methods in a typical case of EC, we found numerous activated eosinophils synthesizing and secreting IL-5 protein.	ec	50-52	interleukin 5	Homo sapiens	121-125
33775691-6	2021	EC strongly induced oxidative stress in both the liver and intestine, and activated the hepatic Nrf2/Gclm/Gclc pathway and the intestinal Nrf2/Ho-1 pathway, respectively, for adaptively regulating oxidative stress.	ec	0-2	NFE2 like bZIP transcription factor 2	Rattus norvegicus	96-100
19912868-9	1992	In competition studies GDA had an EC(50) = 8.8 x 10(-7)M and a detection limit of 2.3 x 10(-7)M. Of the 25 other compounds tested only succinic acid, d-aspartate, quinolinic acid, NMDA, and fumaric acid demonstrated significant cross-reactivity (>0.01%) with the antiserum.	ec	34-36	guanine deaminase	Homo sapiens	23-26
1592489-5	1992	Treatment of EC monolayers with 10(-9) M PAF increased polymorphonuclear leukocyte (PMN) adhesion.	ec	13-15	PCNA-associated factor	Bos taurus	41-44
2258192-7	1990	As the local concentration of IL-2 has been shown to be critical in determining the fate of T cells--whether they become activated or anergic--we have investigated the ability of EC to modulate T-cell IL-2 production, believing that this may underlie their ability to act as costimulatory cells.	ec	179-181	interleukin 2	Homo sapiens	201-205
2258192-8	1990	Using PHA-stimulated peripheral blood mononuclear cells or purified CD4+ T cells we have found that EC can augment IL-2 production, typically by 3- to 8-fold.	ec	100-102	CD4 molecule	Homo sapiens	68-71
2258192-8	1990	Using PHA-stimulated peripheral blood mononuclear cells or purified CD4+ T cells we have found that EC can augment IL-2 production, typically by 3- to 8-fold.	ec	100-102	interleukin 2	Homo sapiens	115-119
1285403-9	1992	Similarly, depletion of biotinylated EC-labeled cells by passage through the streptavidin column enriched CD34+ cells several fold.	ec	37-39	CD34 molecule	Homo sapiens	106-110
1837587-4	1991	After operation, the mean plasma ET-1 concentration in the EC group was significantly higher than the preoperative concentration (p less than 0.01).	ec	59-61	endothelin 1	Homo sapiens	33-37
1837587-7	1991	Additionally in the EC group, a significant correlation existed between plasma ET-1 concentrations after operation and the change in the atrial-natriuretic-peptide (ANP) concentration during operation (p less than 0.05).	ec	20-22	endothelin 1	Homo sapiens	79-83
33775691-6	2021	EC strongly induced oxidative stress in both the liver and intestine, and activated the hepatic Nrf2/Gclm/Gclc pathway and the intestinal Nrf2/Ho-1 pathway, respectively, for adaptively regulating oxidative stress.	ec	0-2	glutamate cysteine ligase, modifier subunit	Rattus norvegicus	101-105
33775691-6	2021	EC strongly induced oxidative stress in both the liver and intestine, and activated the hepatic Nrf2/Gclm/Gclc pathway and the intestinal Nrf2/Ho-1 pathway, respectively, for adaptively regulating oxidative stress.	ec	0-2	glutamate-cysteine ligase, catalytic subunit	Rattus norvegicus	106-110
33775691-6	2021	EC strongly induced oxidative stress in both the liver and intestine, and activated the hepatic Nrf2/Gclm/Gclc pathway and the intestinal Nrf2/Ho-1 pathway, respectively, for adaptively regulating oxidative stress.	ec	0-2	NFE2 like bZIP transcription factor 2	Rattus norvegicus	138-142
33775691-6	2021	EC strongly induced oxidative stress in both the liver and intestine, and activated the hepatic Nrf2/Gclm/Gclc pathway and the intestinal Nrf2/Ho-1 pathway, respectively, for adaptively regulating oxidative stress.	ec	0-2	heme oxygenase 1	Rattus norvegicus	143-147
1171984-4	1975	From 2, [3-thienylalanine]-8-lysine-vasopressin was obtained by removing the Boc-protecting groups with trifluoroacetic acid and ethylcarbamoyl (Ec) protecting groups in refluxing liquid NH3 followed by oxidative cyclization in H2O-MeOH using ICH2CH2I.	ec	145-147	arginine vasopressin	Rattus norvegicus	36-47
35399623-10	2022	Furthermore, EC enhanced the activities of SOD and GSH-Px and decreased MDA level in the liver.	ec	13-15	glutathione peroxidase 1	Rattus norvegicus	51-57
35399623-11	2022	EC treatment also decreased the gene and protein levels of IL-6, IL-1beta, and TNF-alpha in the liver and serum.	ec	0-2	interleukin 6	Rattus norvegicus	59-63
35399623-11	2022	EC treatment also decreased the gene and protein levels of IL-6, IL-1beta, and TNF-alpha in the liver and serum.	ec	0-2	interleukin 1 alpha	Rattus norvegicus	65-73
35399623-11	2022	EC treatment also decreased the gene and protein levels of IL-6, IL-1beta, and TNF-alpha in the liver and serum.	ec	0-2	tumor necrosis factor	Rattus norvegicus	79-88
2962343-9	1987	The addition of human embryonic kidney-conditioned medium, however, abrogated CsA-related inhibition of EC growth, which suggested that CsA indirectly inhibited EC growth, presumably by interfering with CsA-sensitive accessory cells.	ec	104-106	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	78-81
2962343-9	1987	The addition of human embryonic kidney-conditioned medium, however, abrogated CsA-related inhibition of EC growth, which suggested that CsA indirectly inhibited EC growth, presumably by interfering with CsA-sensitive accessory cells.	ec	104-106	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	136-139
2962343-9	1987	The addition of human embryonic kidney-conditioned medium, however, abrogated CsA-related inhibition of EC growth, which suggested that CsA indirectly inhibited EC growth, presumably by interfering with CsA-sensitive accessory cells.	ec	104-106	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	136-139
3862109-7	1985	Because EC-modified LDL is taken up in part by way of the acetyl-LDL receptor, the effects of acetyl-LDL were tested.	ec	8-10	scavenger receptor class F, member 1	Mus musculus	58-77
34578822-5	2021	EC extract reversed ovariectomy-induced deterioration of bone mineral density and bone microarchitecture as well as downregulated cathepsin K (Ctsk) and upregulated runt-related transcription factor 2 (Runx2) and alkaline phosphatase (ALP) in the tibia of OVX rats.	ec	0-2	cathepsin K	Rattus norvegicus	130-141
34578822-5	2021	EC extract reversed ovariectomy-induced deterioration of bone mineral density and bone microarchitecture as well as downregulated cathepsin K (Ctsk) and upregulated runt-related transcription factor 2 (Runx2) and alkaline phosphatase (ALP) in the tibia of OVX rats.	ec	0-2	cathepsin K	Rattus norvegicus	143-147
34578822-5	2021	EC extract reversed ovariectomy-induced deterioration of bone mineral density and bone microarchitecture as well as downregulated cathepsin K (Ctsk) and upregulated runt-related transcription factor 2 (Runx2) and alkaline phosphatase (ALP) in the tibia of OVX rats.	ec	0-2	RUNX family transcription factor 2	Rattus norvegicus	165-200
34578822-5	2021	EC extract reversed ovariectomy-induced deterioration of bone mineral density and bone microarchitecture as well as downregulated cathepsin K (Ctsk) and upregulated runt-related transcription factor 2 (Runx2) and alkaline phosphatase (ALP) in the tibia of OVX rats.	ec	0-2	RUNX family transcription factor 2	Rattus norvegicus	202-207
35548285-8	2022	When EC were suspended in the medium at a presence of 37.84 muM/L ABA, as many as 274 mature cotyledonary embryos/ml PCV of cells were thereafter formed in the mature medium, and 266 somatic embryos were obtained on mature medium after suspension culture in liquid medium containing 10 mmol/L NH4 + and 30 mmol/L NO3 -.	ec	5-7	NBL1, DAN family BMP antagonist	Homo sapiens	313-316
2510332-6	1989	Movement of the EC-bound lymphocyte through the endothelium may be facilitated by IFN-gamma, as suggested by evidence that T cells, bound to the surface of EC monolayers overlying nitrocellulose filters, migrate through these monolayers in increased numbers in the presence of IFN-gamma.	ec	16-18	interferon gamma	Homo sapiens	82-91
2510332-6	1989	Movement of the EC-bound lymphocyte through the endothelium may be facilitated by IFN-gamma, as suggested by evidence that T cells, bound to the surface of EC monolayers overlying nitrocellulose filters, migrate through these monolayers in increased numbers in the presence of IFN-gamma.	ec	16-18	interferon gamma	Homo sapiens	277-286
3489541-12	1986	Overall, these findings suggest that EC, either untreated or pretreated with IFN-beta or IL-2, significantly lose their lytic capabilities following interaction with K562 while retaining their ability to bind to the TC; IFN-beta acts predominantly on pre-NK cells, but not on ECi; and IL-2 appears to play an important role in restoring lytic potential to functionally inactive NK cells.	ec	37-39	interferon beta 1	Homo sapiens	77-85
3489541-12	1986	Overall, these findings suggest that EC, either untreated or pretreated with IFN-beta or IL-2, significantly lose their lytic capabilities following interaction with K562 while retaining their ability to bind to the TC; IFN-beta acts predominantly on pre-NK cells, but not on ECi; and IL-2 appears to play an important role in restoring lytic potential to functionally inactive NK cells.	ec	37-39	interleukin 2	Homo sapiens	89-93
3489541-12	1986	Overall, these findings suggest that EC, either untreated or pretreated with IFN-beta or IL-2, significantly lose their lytic capabilities following interaction with K562 while retaining their ability to bind to the TC; IFN-beta acts predominantly on pre-NK cells, but not on ECi; and IL-2 appears to play an important role in restoring lytic potential to functionally inactive NK cells.	ec	37-39	interferon beta 1	Homo sapiens	220-228
3489541-12	1986	Overall, these findings suggest that EC, either untreated or pretreated with IFN-beta or IL-2, significantly lose their lytic capabilities following interaction with K562 while retaining their ability to bind to the TC; IFN-beta acts predominantly on pre-NK cells, but not on ECi; and IL-2 appears to play an important role in restoring lytic potential to functionally inactive NK cells.	ec	37-39	latexin	Homo sapiens	276-279
3489541-12	1986	Overall, these findings suggest that EC, either untreated or pretreated with IFN-beta or IL-2, significantly lose their lytic capabilities following interaction with K562 while retaining their ability to bind to the TC; IFN-beta acts predominantly on pre-NK cells, but not on ECi; and IL-2 appears to play an important role in restoring lytic potential to functionally inactive NK cells.	ec	37-39	interleukin 2	Homo sapiens	285-289
3471149-11	1986	These findings demonstrate two novel biologic activities of thrombin, the stimulation of EC-dependent adherence of PMNs and the production of PAF by EC, and suggest that they are functionally related.	ec	89-91	coagulation factor II, thrombin	Homo sapiens	60-68
31330363-8	2019	Nine constituents (OC, EC, K, Fe, Zn, Ba, Cr, Se, and Pb) showed consistent associations with elevated FeNO and decreased NOS2A methylation or increased ARG2 methylation in single-constituent models and models adjusting for PM2.5 total mass and collinearity.	ec	23-25	nitric oxide synthase 2	Homo sapiens	122-127
33601378-7	2021	RESULTS: Following TS, EC treatment significantly increased epidermal thickness and lipid content versus diluent in the skin organ culture, as well as claudin-1, involucrin, and caspase-14 expression, suggesting skin barrier repair.	ec	23-25	involucrin	Homo sapiens	162-172
33601378-8	2021	EC treatment also decreased keratin-16 expression and increased levels of Toll-like receptors 1 and 2 versus diluent, suggesting involvement in regulating the epidermal immune response.	ec	0-2	keratin 16	Homo sapiens	28-38
33601378-8	2021	EC treatment also decreased keratin-16 expression and increased levels of Toll-like receptors 1 and 2 versus diluent, suggesting involvement in regulating the epidermal immune response.	ec	0-2	toll like receptor 1	Homo sapiens	74-101
33107073-6	2021	MATERIALS AND METHODS: Tissue inhibitor of metalloproteinases 2 was measured in FFP (n = 30), EC (n = 12) and PI-PC (n = 12) using a Q-Plex single-plex immunoassay for chemiluminescence-based detection.	ec	94-96	TIMP metallopeptidase inhibitor 2	Homo sapiens	23-63
33107073-9	2021	RESULTS: Tissue inhibitor of metalloproteinases 2 was detected in FFP (30/30 samples), EC (11/12 samples) and PI-PC (12/12 samples).	ec	87-89	TIMP metallopeptidase inhibitor 2	Homo sapiens	9-49
33107073-12	2021	CONCLUSION: Tissue inhibitor of metalloproteinases 2 is detectable and stable in FFP, PI-PC and, in low concentration, EC.	ec	119-121	TIMP metallopeptidase inhibitor 2	Homo sapiens	12-52
33439181-6	2021	In this study, novel ER/graphene composites (ECs) were developed, and the wear resistance of EC with 5 wt% graphene (EC5) was shown to be 628 times that of pure ER at 10 N. To the best of our knowledge, the unprecedented enhancement of wear resistance for ER is the highest reported.	ec	45-47	epiregulin	Homo sapiens	21-23
33601378-7	2021	RESULTS: Following TS, EC treatment significantly increased epidermal thickness and lipid content versus diluent in the skin organ culture, as well as claudin-1, involucrin, and caspase-14 expression, suggesting skin barrier repair.	ec	23-25	claudin 1	Homo sapiens	151-160
33065543-4	2020	Although the environment of EC is rich in TGFB and in FOXP3+, CD4+ T cells, the mechanisms leading to tolerance have not been elucidated.	ec	28-30	transforming growth factor beta 1	Homo sapiens	42-46
33065543-4	2020	Although the environment of EC is rich in TGFB and in FOXP3+, CD4+ T cells, the mechanisms leading to tolerance have not been elucidated.	ec	28-30	forkhead box P3	Equus caballus	54-59
33065543-4	2020	Although the environment of EC is rich in TGFB and in FOXP3+, CD4+ T cells, the mechanisms leading to tolerance have not been elucidated.	ec	28-30	CD4 molecule	Equus caballus	62-65
32078753-4	2020	The sensitizing capacity of EC was also reduced in the BALB/c mouse model, which showed the significantly decreased levels of specific IgE, IgG, IgG1 and IgG2a, mMCP-1 and histamine in the mouse sera, as well as cytokine secretions of IL-4, IL-5, and IL-13, compared with the raw egg (RE) group.	ec	28-30	LOC105243590	Mus musculus	145-149
32078753-4	2020	The sensitizing capacity of EC was also reduced in the BALB/c mouse model, which showed the significantly decreased levels of specific IgE, IgG, IgG1 and IgG2a, mMCP-1 and histamine in the mouse sera, as well as cytokine secretions of IL-4, IL-5, and IL-13, compared with the raw egg (RE) group.	ec	28-30	immunoglobulin heavy variable V1-9	Mus musculus	154-159
32078753-4	2020	The sensitizing capacity of EC was also reduced in the BALB/c mouse model, which showed the significantly decreased levels of specific IgE, IgG, IgG1 and IgG2a, mMCP-1 and histamine in the mouse sera, as well as cytokine secretions of IL-4, IL-5, and IL-13, compared with the raw egg (RE) group.	ec	28-30	chemokine (C-C motif) ligand 2	Mus musculus	161-167
32078753-4	2020	The sensitizing capacity of EC was also reduced in the BALB/c mouse model, which showed the significantly decreased levels of specific IgE, IgG, IgG1 and IgG2a, mMCP-1 and histamine in the mouse sera, as well as cytokine secretions of IL-4, IL-5, and IL-13, compared with the raw egg (RE) group.	ec	28-30	interleukin 4	Mus musculus	235-239
32078753-4	2020	The sensitizing capacity of EC was also reduced in the BALB/c mouse model, which showed the significantly decreased levels of specific IgE, IgG, IgG1 and IgG2a, mMCP-1 and histamine in the mouse sera, as well as cytokine secretions of IL-4, IL-5, and IL-13, compared with the raw egg (RE) group.	ec	28-30	interleukin 5	Mus musculus	241-245
32078753-4	2020	The sensitizing capacity of EC was also reduced in the BALB/c mouse model, which showed the significantly decreased levels of specific IgE, IgG, IgG1 and IgG2a, mMCP-1 and histamine in the mouse sera, as well as cytokine secretions of IL-4, IL-5, and IL-13, compared with the raw egg (RE) group.	ec	28-30	interleukin 13	Mus musculus	251-256
31808501-6	2020	The feasibility in the clinical application of the EC sensor was verified by the in vitro detection of CEA in human serum.	ec	51-53	CEA cell adhesion molecule 3	Homo sapiens	103-106
31330363-8	2019	Nine constituents (OC, EC, K, Fe, Zn, Ba, Cr, Se, and Pb) showed consistent associations with elevated FeNO and decreased NOS2A methylation or increased ARG2 methylation in single-constituent models and models adjusting for PM2.5 total mass and collinearity.	ec	23-25	arginase 2	Homo sapiens	153-157
31464311-8	2019	The Li+ and Mg2+ intercalation is directed by the kind of the used electrolyte: a lithium electrolyte consisting of 1 M LiPF6 solution in EC : DMC and a magnesium electrolyte consisting of 0.5 Mg(TFSI)2 solution in diglyme.	ec	138-140	mucin 7, secreted	Homo sapiens	12-15
30985390-7	2019	After EC was implemented (period 2), 65% of patients stood, 54% walked at least once during their ICU stay, and ICU-acquired pressure ulcers and physical restraint use decreased (period 1 vs 2: 39% vs 23% of patients; 30% vs 26% patient days, respectively; p < 0.001 for both).	ec	6-8	period circadian regulator 2	Homo sapiens	26-34
31419538-9	2019	In the 15-day SF group, L-tryptophan, myristoylcarnitine, and palmitoylcarnitine were significantly increased, while adenosine monophosphate, hypoxanthine, L-glutamate, L-aspartate, L-methionine, and glycerophosphocholine were decreased compared to the EC group.	ec	253-255	hepatocyte growth factor	Rattus norvegicus	14-16
29372658-5	2019	About 96 h exposure to sublethal concentrations (0, 12.0 and 25.0 mug/L) of the commercial formulation (20% EC) of chlorpyrifos reduced the level of hepatic glycogen, activities of alkaline phosphatase, acetylcholinesterase, and catalase in liver and elevated the level of plasma glucose and activities of hepatic acid phosphatase, aspartate aminotransferase, and alanine aminotransferase in O. niloticus.	ec	108-110	catalase	Oreochromis niloticus	181-237
31038020-3	2019	Three experiments were conducted: (1) Assessment of the effect of RNase A-treated EC-12 on transcriptome profiles and biological pathways in human peripheral blood mononuclear cells; (2) Determination of cytokine concentration in its culture supernatants; and (3) Supplementation of RNase A-treated EC-12 (RN) to mice with dextran sodium sulfate-induced colitis.	ec	82-84	ribonuclease A family member 1, pancreatic	Homo sapiens	66-73
31357705-4	2019	(3) Results: Compared with the control group, EC group significantly elevated the serum aspartate aminotransferase (AST), alanine aminitransferase (ALT), and lactate dehydrogenase (LDH).	ec	46-48	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	88-114
31357705-4	2019	(3) Results: Compared with the control group, EC group significantly elevated the serum aspartate aminotransferase (AST), alanine aminitransferase (ALT), and lactate dehydrogenase (LDH).	ec	46-48	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	116-119
30236704-6	2019	Irradiated TCPF and EC are more potent AChE inhibitors than irradiated EW.	ec	20-22	acetylcholinesterase (Cartwright blood group)	Homo sapiens	39-43
30721559-6	2019	Furthermore, CHA-NT4-derived EC (human nuclear transfer [hNT]-ESC-EC) transplantation in hind limb ischemic mice rescued the hind limb and restored blood perfusion.	ec	29-31	neurotrimin	Homo sapiens	57-60
31057416-11	2019	After the 1st RE bout, the EC group showed significantly higher p70S6K Thr389 phosphorylation than the IC group.	ec	27-29	ribosomal protein S6 kinase B1	Rattus norvegicus	64-70
30773245-12	2019	In Trial 2, uterine flushing was accomplished in 78% of ewes in the EB-PGF-OT and 44% of those in the EC-PGF-OT group (P>0.05) with mean flushing fluid recovery rate being 88% and time elapsing to complete flushing being ~33 min.	ec	102-104	placental growth factor	Homo sapiens	105-108
30866432-5	2019	We found that a degree of EC-induced p70S6K phosphorylation and the rate of PS in the soleus of 3- and 7-day unloaded rats was significantly less than that in control.	ec	26-28	ribosomal protein S6 kinase B1	Rattus norvegicus	37-43
30866432-6	2019	A decrease in EC-induced phosphorylation of p70S6K, RPS6 and PS in the 7-day unloaded soleus treated with SAC inhibitor did not differ from that of the 7-day unloaded soleus without SAC blockade.	ec	14-16	ribosomal protein S6 kinase B1	Rattus norvegicus	44-50
30866432-6	2019	A decrease in EC-induced phosphorylation of p70S6K, RPS6 and PS in the 7-day unloaded soleus treated with SAC inhibitor did not differ from that of the 7-day unloaded soleus without SAC blockade.	ec	14-16	ribosomal protein S6	Rattus norvegicus	52-56
30136422-12	2018	These differences were too subtle in healthy elderly to use EC for single-subject prediction of APOE genotype.	ec	60-62	apolipoprotein E	Homo sapiens	96-100
30289911-14	2018	EC extract administration also decreased pro-inflammatory cytokine expression, increased IL-10 levels, and reduced colonic damage.	ec	0-2	interleukin 10	Mus musculus	89-94
30157275-9	2018	Of the ESBL-EC isolates, CTX-M-27 was the most prevalent (33.3%), followed by CTX-M-14 (30%).	ec	12-14	EsbL	Escherichia coli	7-11
30157275-9	2018	Of the ESBL-EC isolates, CTX-M-27 was the most prevalent (33.3%), followed by CTX-M-14 (30%).	ec	12-14	CTX-M-14	Escherichia coli	78-86
30157275-12	2018	The 14-day mortality non-ESBL-EC, ESBL-EC, and ESBL/IMP-6-EC was 4.7% (4/85), 20% (6/30), and 66.7% (2/3), respectively.	ec	30-32	EsbL	Escherichia coli	25-29
30062338-10	2018	To the best of our knowledge, this is the first time a fabric-based electrode has been reported for EC-SERS investigations, highlighting a promising platform for wearable point-of-care sensors.	ec	100-102	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	103-107
29866423-9	2018	In 15 cases of EC mixed with CCC, IMP3 showed a better discrimination value than the other two markers.	ec	15-17	IMP U3 small nucleolar ribonucleoprotein 3	Homo sapiens	34-38
28289099-5	2017	Moreover, we found that the magnitude of the EC-induced activation of mTOR signaling was significantly blunted in muscles from both inducible and skeletal muscle-specific knock-out mice for Rheb and iTSC2KO mice.	ec	45-47	mechanistic target of rapamycin kinase	Mus musculus	70-74
28187032-5	2018	A significantly higher SHP-1 expression was observed in the Ec group compared with the Sc group (P=0.0005, Fisher exact test).	ec	60-62	protein tyrosine phosphatase non-receptor type 6	Homo sapiens	23-28
28187032-6	2018	In the Ec group, SHP-1 immunoreactivity was correlated with grading, demonstrating that more differentiated lesions expressed SHP-1 more frequently than less differentiated neoplasms (G1 vs. G2, P=0.0243, statistically significant value, Fisher exact test; G1 vs. G3, P=0.0088, extremely significant value, Fisher exact test).	ec	7-9	protein tyrosine phosphatase non-receptor type 6	Homo sapiens	17-22
28187032-6	2018	In the Ec group, SHP-1 immunoreactivity was correlated with grading, demonstrating that more differentiated lesions expressed SHP-1 more frequently than less differentiated neoplasms (G1 vs. G2, P=0.0243, statistically significant value, Fisher exact test; G1 vs. G3, P=0.0088, extremely significant value, Fisher exact test).	ec	7-9	protein tyrosine phosphatase non-receptor type 6	Homo sapiens	126-131
29333092-8	2018	We found that the majority of EC subjects (23/30; 77%) presented allelic combinations leading to an inactive A3H protein, a frequency slightly lower than that observed for NC studied patients (10/11; 91%).	ec	30-32	apolipoprotein B mRNA editing enzyme catalytic subunit 3H	Homo sapiens	109-112
28532672-1	2017	In this study, we found that catechins found in green tea (EGCG, EGC, and EC) differentially interfere with the IL-1beta signaling pathway which regulates the expression of pro-inflammatory mediators (IL-6 and IL-8) and Cox-2 in primary human rheumatoid arthritis synovial fibroblasts (RASFs).	ec	74-76	interleukin 1 beta	Homo sapiens	112-120
28532672-1	2017	In this study, we found that catechins found in green tea (EGCG, EGC, and EC) differentially interfere with the IL-1beta signaling pathway which regulates the expression of pro-inflammatory mediators (IL-6 and IL-8) and Cox-2 in primary human rheumatoid arthritis synovial fibroblasts (RASFs).	ec	74-76	interleukin 6	Homo sapiens	201-205
28532672-1	2017	In this study, we found that catechins found in green tea (EGCG, EGC, and EC) differentially interfere with the IL-1beta signaling pathway which regulates the expression of pro-inflammatory mediators (IL-6 and IL-8) and Cox-2 in primary human rheumatoid arthritis synovial fibroblasts (RASFs).	ec	74-76	C-X-C motif chemokine ligand 8	Homo sapiens	210-214
28532672-1	2017	In this study, we found that catechins found in green tea (EGCG, EGC, and EC) differentially interfere with the IL-1beta signaling pathway which regulates the expression of pro-inflammatory mediators (IL-6 and IL-8) and Cox-2 in primary human rheumatoid arthritis synovial fibroblasts (RASFs).	ec	74-76	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	220-225
28532672-6	2017	Molecular docking analysis confirms that EGCG, EGC, and EC all occupy the active site of the TAK1 kinase domain.	ec	56-58	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	93-97
27955803-2	2017	We therefore carried out oral acute toxicity study, and then investigated the effects of various doses of EC on the activities of lactate dehydrogenase (LDH), catalase (CAT), and superoxide dismutase (SOD), as well as reduced glutathione (GSH) and malondialdehyde (MDA) levels in wistar rats.	ec	106-108	catalase	Rattus norvegicus	159-167
27955803-2	2017	We therefore carried out oral acute toxicity study, and then investigated the effects of various doses of EC on the activities of lactate dehydrogenase (LDH), catalase (CAT), and superoxide dismutase (SOD), as well as reduced glutathione (GSH) and malondialdehyde (MDA) levels in wistar rats.	ec	106-108	catalase	Rattus norvegicus	169-172
29206487-1	2018	The treatment of human pulmonary artery smooth muscle cells with ET-1 stimulates the activity of PLD and NADPH oxidase, but this stimulation is inhibited by pretreatment with bosentan (ET-1 receptor antagonist), FIPI (PLD inhibitor), apocynin (NADPH oxidase inhibitor), and EGCG and ECG (catechins having a galloyl group), but not EGC and EC (catechins devoid of a galloyl group).	ec	283-285	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	97-100
29206487-1	2018	The treatment of human pulmonary artery smooth muscle cells with ET-1 stimulates the activity of PLD and NADPH oxidase, but this stimulation is inhibited by pretreatment with bosentan (ET-1 receptor antagonist), FIPI (PLD inhibitor), apocynin (NADPH oxidase inhibitor), and EGCG and ECG (catechins having a galloyl group), but not EGC and EC (catechins devoid of a galloyl group).	ec	283-285	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	218-221
29206487-6	2018	The molecular docking analyses revealed that the catechins containing a galloyl group (EGCG and ECG) with cytohesin-1-Arf6GDP, but not the catechins without a galloyl group (EGC and EC), prevent GDP-GTP exchange in Arf6, which seems to be an important mechanism for inhibiting the activation of PLD induced by ET-1, and subsequently increases the activity of NADPH oxidase.	ec	96-98	cytohesin 1	Homo sapiens	106-125
29206487-6	2018	The molecular docking analyses revealed that the catechins containing a galloyl group (EGCG and ECG) with cytohesin-1-Arf6GDP, but not the catechins without a galloyl group (EGC and EC), prevent GDP-GTP exchange in Arf6, which seems to be an important mechanism for inhibiting the activation of PLD induced by ET-1, and subsequently increases the activity of NADPH oxidase.	ec	96-98	ADP ribosylation factor 6	Homo sapiens	118-122
28013477-3	2017	Our present study revealed that among the four green tea catechins (EGCG, ECG, EC, and EGC), EGCG and ECG inhibit pro-/active MMP-2 activities in pulmonary artery smooth muscle cell (PASMC) culture supernatant.	ec	74-76	matrix metallopeptidase 2	Homo sapiens	126-131
28289099-5	2017	Moreover, we found that the magnitude of the EC-induced activation of mTOR signaling was significantly blunted in muscles from both inducible and skeletal muscle-specific knock-out mice for Rheb and iTSC2KO mice.	ec	45-47	Ras homolog enriched in brain	Mus musculus	190-194
27621462-2	2016	Recent work has shown that EC coupling fails in muscle from mice and fish null for the protein Stac3 (SH3 and cysteine-rich domain 3) but did not establish the functional role of Stac3 in the CaV1.1-RyR1 interaction.	ec	27-29	SH3 and cysteine rich domain 3	Homo sapiens	95-100
27043860-7	2016	CYP2E1 expression was significantly increased in the EC group compared with the NC group, but was significantly suppressed in the PV group compared with the EC group (p = 0.044).	ec	53-55	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	0-6
27043860-7	2016	CYP2E1 expression was significantly increased in the EC group compared with the NC group, but was significantly suppressed in the PV group compared with the EC group (p = 0.044).	ec	157-159	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	0-6
27668533-3	2016	The present study demonstrated that among the four green tea catechins (EGCG, ECG, EC and EGC), EGCG and ECG inhibit pro-/active MMP-9 activities in pulmonary artery smooth muscle cell culture supernatant.	ec	78-80	matrix metallopeptidase 9	Homo sapiens	129-134
27034797-1	2016	BACKGROUND: SPARC-like protein 1 (SPARCL1/Hevin), a member of the SPARC family is defined by the presence of a highly acidic domain-I, a follistatin-like domain, and an extracellular calcium (EC) binding domain.	ec	192-194	SPARC like 1	Homo sapiens	12-32
27084395-6	2016	Immunofluorescence co-localized increased CYP4A12 expression in response to ischemia to CD31-positive EC in the ischemic hindlimb microvessels.	ec	102-104	cytochrome P450, family 4, subfamily a, polypeptide 12a	Mus musculus	42-49
27382377-9	2016	EC+PBS mixture reduced the production of PGE2, NO, IL-1beta, and IL-6.	ec	0-2	interleukin 1 beta	Rattus norvegicus	51-59
27382377-9	2016	EC+PBS mixture reduced the production of PGE2, NO, IL-1beta, and IL-6.	ec	0-2	interleukin 6	Rattus norvegicus	65-69
27084395-6	2016	Immunofluorescence co-localized increased CYP4A12 expression in response to ischemia to CD31-positive EC in the ischemic hindlimb microvessels.	ec	102-104	platelet/endothelial cell adhesion molecule 1	Mus musculus	88-92
27034797-1	2016	BACKGROUND: SPARC-like protein 1 (SPARCL1/Hevin), a member of the SPARC family is defined by the presence of a highly acidic domain-I, a follistatin-like domain, and an extracellular calcium (EC) binding domain.	ec	192-194	SPARC like 1	Homo sapiens	34-41
26318299-7	2016	Biochemical analysis showed that solid EC induced a significant increase in malondialdehyde (MDA) content with a significant decrease in the antioxidant state (glutathione peroxidase (GPx) and catalase (CAT) activities) and depleted serum iron concentration compared to normal control.	ec	39-41	catalase	Mus musculus	193-201
26695097-8	2016	Here we report the successful use of EC as a partial reduction approach in mapping of disulfide bonds of intact human insulin (HI) and lysozyme.	ec	37-39	insulin	Homo sapiens	118-125
26318299-7	2016	Biochemical analysis showed that solid EC induced a significant increase in malondialdehyde (MDA) content with a significant decrease in the antioxidant state (glutathione peroxidase (GPx) and catalase (CAT) activities) and depleted serum iron concentration compared to normal control.	ec	39-41	catalase	Mus musculus	203-206
24758270-16	2014	Compared with E group, EC group showed significantly decreased level of serum DAO and I-FABP (p < 0.05).	ec	23-25	amine oxidase copper containing 1	Homo sapiens	78-81
27321096-5	2016	This was the reason of our study in which we proposed investigation of HE4 levels as a complementary diagnostic method in management and diagnosing of EC.	ec	151-153	WAP four-disulfide core domain 2	Homo sapiens	71-74
30603385-2	2016	In this study, we found that a peptide (16 amino acids in length), which is located in the extracellular calcium (EC) binding domain of SMOC1, stimulated osteogenic differentiation of human BMSCs in vitro and calvarial bone regeneration in vivo.	ec	114-116	SPARC related modular calcium binding 1	Homo sapiens	136-141
25294549-6	2015	However, the curative resection rate was significantly better in the SM1 EC group (69.0%) compared to that in SM1 non-EC and SM2-GC groups (0% in both cases).	ec	73-75	SM1	Homo sapiens	69-72
25483146-8	2015	It is believed that routine and early diagnosis of disease could be possible through such quantitative detection of biomarkers in patient samples using this EC-SERS method.	ec	157-159	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	160-164
25211240-6	2014	Among them, PC1 (C1-, Na+, SO4(2-), EC, and pH) and PC2 (Ca2+, K+, Mg2+and total amount of salts) are considered to be mainly influenced by artificial sources, while PC3 and PC4 (CO3(-) and HCO3(2-)) are mainly influenced by natural sources.	ec	36-38	proprotein convertase subtilisin/kexin type 1	Homo sapiens	12-15
24948646-8	2014	In addition, EC exposure can be associated with altered expression of GnRH, GnRH receptors, galanin receptors, and kisspeptin mRNA within the hypothalamus and pituitary gland, gonadotroph populations within the pituitary gland, and regional aberrations in thyroid morphology.	ec	13-15	gonadotropin releasing hormone 1	Homo sapiens	70-74
24948646-8	2014	In addition, EC exposure can be associated with altered expression of GnRH, GnRH receptors, galanin receptors, and kisspeptin mRNA within the hypothalamus and pituitary gland, gonadotroph populations within the pituitary gland, and regional aberrations in thyroid morphology.	ec	13-15	gonadotropin releasing hormone 1	Homo sapiens	76-80
24948056-5	2014	RESULTS: Current work showed that EC immunization with phosphorylcholine conjugated to bovine serum albumin (PC-BSA) and CpG prior to Streptococcus pneumoniae infection results in smaller decrease of body weight when compared to PBS treated mice.	ec	34-36	albumin	Mus musculus	94-107
24769164-6	2014	The strain with the homozygous CAR1 deletion showed significant reductions of urea and EC in the final spirits in comparison to the parental strain, with the concentration reductions by 86.9% and 50.5% respectively.	ec	87-89	arginase	Saccharomyces cerevisiae S288C	31-35
26544698-9	2015	Furthermore, the EC group maintained a stable CD4% during a median follow-up of 6 years.	ec	17-19	CD4 molecule	Homo sapiens	46-49
25888925-12	2015	Moreover, HGF levels in the MSC-EC interaction group were much higher than those of the MSC group.	ec	32-34	hepatocyte growth factor	Homo sapiens	10-13
26913147-3	2015	The DHPR has several key modules required for EC coupling: the voltage sensors and II-III loop in the alpha1s subunit, and the beta subunit.	ec	46-48	calcium voltage-gated channel subunit alpha1 S	Homo sapiens	4-8
25025269-7	2014	The reaction procedure can be well-monitored by cyclic voltammetry (CV), electrochemical surface enhanced Raman microscopy (EC-SERS), and X-ray photoelectron spectroscopy (XPS).	ec	124-126	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	127-131
24758270-16	2014	Compared with E group, EC group showed significantly decreased level of serum DAO and I-FABP (p < 0.05).	ec	23-25	fatty acid binding protein 2	Homo sapiens	86-92
24389091-5	2014	CORT treatment elevated EC level (p<0.05) and reduced liver glycogen content (p<0.05).	ec	24-26	CORT	Gallus gallus	0-4
24457250-2	2014	In this study, we examined whether an EC could enhance anxiolytic behavior in the Indian field mouse Mus booduga by down-regulating the expression of glucocorticoid receptor (GR) through microRNA-124a.	ec	38-40	nuclear receptor subfamily 3, group C, member 1	Mus musculus	150-173
23830461-9	2013	In this study, an EC18-ELP fusion protein was expressed in Escherichia coli and the metal binding ability of EC to cadmium was examined quantitatively.	ec	18-20	nuclear receptor subfamily 5 group A member 1	Homo sapiens	23-26
28664069-10	2013	Regarding IGF-1 mRNA, the USN-EC group showed significantly higher expressions in the red muscle of the gastrocnemius and liver than the Sham-Pre and USN-CLA groups.	ec	30-32	insulin-like growth factor 1	Rattus norvegicus	10-15
23327913-19	2012	The contents of IL-1beta in supernatants of normal fibroblasts and scar fibroblasts in groups of every concentration of oleic acid were significantly higher than those in corresponding BC and EC groups (with F values respectively 25.117, 9.137, P values all below 0.01).	ec	192-194	interleukin 1 beta	Homo sapiens	16-24
23628149-7	2013	Compared with E group, EC group showed renal tissue IL-1beta, IL-6, TNF-alpha and NF-KB expression decreased significantly, respectively (p < 0.05).	ec	23-25	interleukin 1 beta	Homo sapiens	52-60
23628149-7	2013	Compared with E group, EC group showed renal tissue IL-1beta, IL-6, TNF-alpha and NF-KB expression decreased significantly, respectively (p < 0.05).	ec	23-25	interleukin 6	Homo sapiens	62-66
23628149-7	2013	Compared with E group, EC group showed renal tissue IL-1beta, IL-6, TNF-alpha and NF-KB expression decreased significantly, respectively (p < 0.05).	ec	23-25	tumor necrosis factor	Homo sapiens	68-77
23853481-6	2013	Of the 103 ESBL-EC isolates, 43 (41.7%) produced CTX-M-14 and 36 (35.0%) produced CTX-M-15.	ec	16-18	EsbL	Escherichia coli	11-15
23532856-11	2013	The data suggest an alternative to EC uptake of soluble MPO, namely the cell contact-dependent, beta2 integrin-mediated transfer from neutrophils.	ec	35-37	myeloperoxidase	Mus musculus	56-59
24228027-6	2013	EC was able to decrease oxidative stress and was also able to decrease signaling for mucin synthesis, at least a part, via reducing the ligand in chronic coal dust exposure.	ec	0-2	solute carrier family 13 member 2	Rattus norvegicus	85-90
22645323-7	2012	CONCLUSIONS: A regimen of early intensified EC-MPS dosing with calcineurin inhibitor and IL-2RA induction permits oral steroid avoidance in adult kidney transplant patients at low-immunological risk without compromising efficacy at 6 months" follow-up.	ec	44-46	calcineurin binding protein 1	Homo sapiens	63-84
22709867-3	2012	The 1,5-bis(3-bromo-4-methoxyphenyl)penta-1,4-dien-3-one 4 (EC(50) vs EZH2 = 74.9 muM), tested in U937 cells at 50 muM, induced massive cell death and 28% of granulocytic differentiation, highlighting the potential use of EZH2 inhibitors in cancer.	ec	60-62	latexin	Homo sapiens	82-85
22709867-3	2012	The 1,5-bis(3-bromo-4-methoxyphenyl)penta-1,4-dien-3-one 4 (EC(50) vs EZH2 = 74.9 muM), tested in U937 cells at 50 muM, induced massive cell death and 28% of granulocytic differentiation, highlighting the potential use of EZH2 inhibitors in cancer.	ec	60-62	latexin	Homo sapiens	115-118
22709867-3	2012	The 1,5-bis(3-bromo-4-methoxyphenyl)penta-1,4-dien-3-one 4 (EC(50) vs EZH2 = 74.9 muM), tested in U937 cells at 50 muM, induced massive cell death and 28% of granulocytic differentiation, highlighting the potential use of EZH2 inhibitors in cancer.	ec	60-62	enhancer of zeste 2 polycomb repressive complex 2 subunit	Homo sapiens	222-226
23267980-3	2012	She underwent NAC with EC followed by docetaxel.	ec	23-25	X-linked Kx blood group	Homo sapiens	14-17
22571796-2	2012	In this study, the following frequencies for each of three ACE polymorphisms, DD, ID, and II, respectively, were observed: in the EC group, 55, 24, and 21% versus the control group 39, 40, and 21% (p = 0.033*); in the EOC group 49, 36, and 15% versus the control group 49, 33, and 18% (p = 0.82).	ec	130-132	angiotensin I converting enzyme	Homo sapiens	59-62
21959517-7	2011	RESULTS: The perfusion with UW and EC solution caused an increase of renin I, angiotensinogen and angiotensin I-converting enzyme genes expression in kidneys.	ec	35-37	renin	Rattus norvegicus	69-74
21813270-6	2012	Expression of the hepatic cytochrome P450 2E1 (CYP2E1) protein in the EP group was significantly lower than that in the EC group, and the hepatic peroxisome proliferator-activated receptor (PPAR) alpha and cytochrome P450 4A (CYP4A) protein expressions in the EP group were significantly higher than those in the EC group.	ec	120-122	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	26-45
21883617-8	2012	This suggests that EC may participate in the inhibition of IFN-gamma-dependent apoptosis and, therefore, play important role for DC survival in a cytokine-enriched placental environment.	ec	19-21	interferon gamma	Mus musculus	59-68
23067124-2	2012	The discovery of threosyl phosphonate nucleoside (PMDTA, EC(50) = 2.53 muM) as a potent antihuman immunodeficiency virus (anti-HIV) agent has led to the synthesis and biological evaluation of 3"-modified 5"-deoxy versions of the threosyl phosphonate nucleosides.	ec	57-59	latexin	Homo sapiens	71-74
21959517-7	2011	RESULTS: The perfusion with UW and EC solution caused an increase of renin I, angiotensinogen and angiotensin I-converting enzyme genes expression in kidneys.	ec	35-37	angiotensin I converting enzyme	Rattus norvegicus	98-129
22426689-3	2012	However, oral administration of EC (0.12 and 0.24 mL/10 g per day, 7 d) was found to reduce the increased plasma ALT and AST levels in stressed mice.	ec	32-34	glutamic pyruvic transaminase, soluble	Mus musculus	113-116
22426689-3	2012	However, oral administration of EC (0.12 and 0.24 mL/10 g per day, 7 d) was found to reduce the increased plasma ALT and AST levels in stressed mice.	ec	32-34	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	121-124
22426689-6	2012	In addition, EC administration was found to resist a stress-induced increase of plasma corticosterone levels and down-regulation of liver glucocorticoid receptor gene expression.	ec	13-15	nuclear receptor subfamily 3, group C, member 1	Mus musculus	138-161
22533850-2	2012	The monosubstituted 5"-O-fatty acyl derivatives of 3TC (EC(50) = 0.2-2.3 muM) were more potent than the corresponding monosubstituted N(4)-fatty acyl (EC(50) = 0.4-29.4 muM) and 5"-O-N(4)-disubstituted (EC(50) = 72.6 to >154.0 muM) derivatives of the nucleoside.	ec	56-58	latexin	Homo sapiens	73-76
22364701-5	2012	Greater EC adhesion was observed on hydrogels presenting 1:1 anti-VCAM1:anti-E-Selectin than on gels presenting either arginine-glycine-asparagine (RGD) peptide, anti-VCAM1, or anti-E-Selectin alone.	ec	8-10	vascular cell adhesion molecule 1	Homo sapiens	66-71
22364701-5	2012	Greater EC adhesion was observed on hydrogels presenting 1:1 anti-VCAM1:anti-E-Selectin than on gels presenting either arginine-glycine-asparagine (RGD) peptide, anti-VCAM1, or anti-E-Selectin alone.	ec	8-10	selectin E	Homo sapiens	77-87
22364701-5	2012	Greater EC adhesion was observed on hydrogels presenting 1:1 anti-VCAM1:anti-E-Selectin than on gels presenting either arginine-glycine-asparagine (RGD) peptide, anti-VCAM1, or anti-E-Selectin alone.	ec	8-10	vascular cell adhesion molecule 1	Homo sapiens	167-172
22364701-5	2012	Greater EC adhesion was observed on hydrogels presenting 1:1 anti-VCAM1:anti-E-Selectin than on gels presenting either arginine-glycine-asparagine (RGD) peptide, anti-VCAM1, or anti-E-Selectin alone.	ec	8-10	selectin E	Homo sapiens	182-192
21199328-8	2011	Notably, EC was associated with the activation of sphingosine kinase 1 (SphK1) and with increased endogenous S1P synthesis, further stressing the relevance of S1P in skeletal muscle protection and repair/regeneration.	ec	9-11	sphingosine kinase 1	Homo sapiens	50-70
21199328-8	2011	Notably, EC was associated with the activation of sphingosine kinase 1 (SphK1) and with increased endogenous S1P synthesis, further stressing the relevance of S1P in skeletal muscle protection and repair/regeneration.	ec	9-11	sphingosine kinase 1	Homo sapiens	72-77
21959517-7	2011	RESULTS: The perfusion with UW and EC solution caused an increase of renin I, angiotensinogen and angiotensin I-converting enzyme genes expression in kidneys.	ec	35-37	angiotensinogen	Rattus norvegicus	78-93
20471964-6	2010	Four related catechins, EGCG, ECG, EGC ((-)-epigallocatechin) and EC ((-)-epicatechin) showed a rank order of activity toward RyR1 (EGCG>ECG>>EGC>>>EC).	ec	30-32	ryanodine receptor 1	Homo sapiens	126-130
21042803-8	2011	Western blot analyses revealed that EC and EGCG prevented down-regulation of Cx26 and Cx43 proteins in HaCaT cells treated with PMA.	ec	36-38	gap junction protein beta 2	Homo sapiens	77-81
21042803-8	2011	Western blot analyses revealed that EC and EGCG prevented down-regulation of Cx26 and Cx43 proteins in HaCaT cells treated with PMA.	ec	36-38	gap junction protein alpha 1	Homo sapiens	86-90
22046186-7	2011	EC had positive predictive value of 85.0% for CD4/CD8 ratio <0.30.	ec	0-2	CD4 molecule	Homo sapiens	46-49
22046186-7	2011	EC had positive predictive value of 85.0% for CD4/CD8 ratio <0.30.	ec	0-2	CD8a molecule	Homo sapiens	50-53
20124479-7	2010	EC uptake of Tspan8-CD49d complex-containing exosomes was accompanied by enhanced EC proliferation, migration, sprouting, and maturation of EC progenitors.	ec	0-2	tetraspanin 8	Rattus norvegicus	13-19
20371687-7	2010	TOP2A gene expression was significantly associated with the metastasis-free interval (MFI; P < 0.001) and was associated with complete remission in patients treated with EC (P = 0.002).	ec	173-175	DNA topoisomerase II alpha	Homo sapiens	0-5
18201784-5	2008	Furthermore, EC were incubated with pitavastatin or cerivastatin for 30 min, Western blot analysis showed that pitavastatin (0.1 microM) significantly upregulated the phosphorylation of eNOS and Akt about 1.4-fold or 1.3-fold compared with control, however, cerivastatin (0.1 microM) did not have any effects on them.	ec	13-15	AKT serine/threonine kinase 1	Homo sapiens	195-198
19692377-6	2009	RESULTS: Significantly more eosinophils were detected in the blood and conjunctivas of IL-5-electroporated mice in which EC was not induced.	ec	121-123	interleukin 5	Mus musculus	87-91
19507304-3	2009	BmDopR1 showed a dose-dependent increase in cAMP levels at DA concentrations up to 10(-7) M with EC(50) of 3.30 nM, while BmDopR2 required 10(-6) M DA for activation.	ec	97-99	dopamine receptor-1	Bombyx mori	0-7
18971283-5	2009	HLA-B*57 was associated with lower VRC (P = 0.0002) than were other alleles in both EC and CP groups.	ec	84-86	major histocompatibility complex, class I, B	Homo sapiens	0-5
19879752-2	2009	Compound 6 showed an ex vivo EC(50) of 10.5 microM and in vitro selectivity for binding to the recombinant alphaA-domain of CD11b/CD18.	ec	29-31	integrin subunit alpha M	Homo sapiens	124-129
19878548-3	2009	Prevalence at birth for the whole spectrum is reported at 1/10,000, ranging from 1/30,000 for CEB to 1/200,000 for EC, with an overall greater proportion of affected males.	ec	115-117	angiotensin II receptor type 1	Homo sapiens	55-110
19170864-9	2009	Oxytocin and corticotrophin releasing factor (CRF) inhibited the monosynaptic amplitude (EC(50), 1.4 +/- 1.0 nM and EC(50) 4.3 +/- 3.5 nM, respectively), polysynaptic amplitude (EC(50) 18.2 +/- 28.0 nM and EC(50), 9.5 +/- 13.3 nM, respectively), and area (EC(50) 11.6 +/- 13.0 nM and EC(50), 2.8 +/- 3.3 nM, respectively); effects that were abolished by oxytocin and CRF(1) antagonists, L-368899 and 8w.	ec	89-91	corticotropin releasing hormone	Rattus norvegicus	13-44
18801367-8	2008	The receptor assay was sensitive to p,p"-DDT, o,p"-DDT and p,p"-DDE with EC(50) of 2.41x10(-6), 3.47x10(-7) and 3.81x10(-5)M. When compared to results obtained from human, zebrafish, chicken, salamander and turtle, the vulture ERalpha showed high sensitivity to o,p"-DDT and intermediately responsive to p,p"-DDE.	ec	73-75	estrogen receptor 1	Gallus gallus	227-234
17662475-5	2007	The replicon cells were subjected to treatment with several antiviral compounds and inhibition of the replicon was observed in treatment with known nucleoside analog inhibitors of NS5 such as 2"-C-methyladenosine (EC(50)=2.42 +/- 0.59 microM), or ribavirin (EC(50)=6.77 +/- 1.33 microM), mycophenolic acid (EC(50)=1.31 +/- 0.27 microM) and siRNA against NS3.	ec	214-216	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	180-183
18067590-9	2008	Compared with the EC group, the expression of NHE3 and NBC1 was increased in the HC group and decreased in the EB group.	ec	18-20	solute carrier family 9 member A3	Rattus norvegicus	46-50
18067590-9	2008	Compared with the EC group, the expression of NHE3 and NBC1 was increased in the HC group and decreased in the EB group.	ec	18-20	solute carrier family 4 member 4	Rattus norvegicus	55-59
18622042-5	2008	In the EC, only 22% of serotonin 5-HT2A-positive neurons were positive for serotonin 5-HT1A receptor-immunoreactivity.	ec	7-9	5-hydroxytryptamine receptor 2A	Rattus norvegicus	33-39
18622042-5	2008	In the EC, only 22% of serotonin 5-HT2A-positive neurons were positive for serotonin 5-HT1A receptor-immunoreactivity.	ec	7-9	5-hydroxytryptamine receptor 1A	Rattus norvegicus	75-100
17662475-5	2007	The replicon cells were subjected to treatment with several antiviral compounds and inhibition of the replicon was observed in treatment with known nucleoside analog inhibitors of NS5 such as 2"-C-methyladenosine (EC(50)=2.42 +/- 0.59 microM), or ribavirin (EC(50)=6.77 +/- 1.33 microM), mycophenolic acid (EC(50)=1.31 +/- 0.27 microM) and siRNA against NS3.	ec	214-216	KRAS proto-oncogene, GTPase	Homo sapiens	354-357
18042273-11	2007	ESR1 expression was appreciably higher in malignant compared to benign tissues and there was a significant effect of EC on the magnitude of the error associated with the relative quantity of ESR1.	ec	117-119	estrogen receptor 1	Homo sapiens	191-195
17297610-2	2007	This study investigated possible correlations of intra-tumoral LATS1 and LATS2 mRNA levels with response to epirubicin plus cyclophosphamide (EC) or docetaxel (DOC) treatment.	ec	142-144	large tumor suppressor kinase 2	Homo sapiens	73-78
17893340-3	2007	EC, but not i.p., immunization of mice with OVA drove the generation of IL-17-producing T cells in draining lymph nodes and spleen and increased serum IL-17 levels.	ec	0-2	interleukin 17A	Mus musculus	72-77
17893340-3	2007	EC, but not i.p., immunization of mice with OVA drove the generation of IL-17-producing T cells in draining lymph nodes and spleen and increased serum IL-17 levels.	ec	0-2	interleukin 17A	Mus musculus	151-156
17893340-4	2007	OVA inhalation by EC-sensitized mice induced IL-17 and CXCL2 expression and neutrophil influx in the lung along with bronchial hyperreactivity, which were reversed by IL-17 blockade.	ec	18-20	interleukin 17A	Mus musculus	45-50
17893340-4	2007	OVA inhalation by EC-sensitized mice induced IL-17 and CXCL2 expression and neutrophil influx in the lung along with bronchial hyperreactivity, which were reversed by IL-17 blockade.	ec	18-20	chemokine (C-X-C motif) ligand 2	Mus musculus	55-60
17893340-4	2007	OVA inhalation by EC-sensitized mice induced IL-17 and CXCL2 expression and neutrophil influx in the lung along with bronchial hyperreactivity, which were reversed by IL-17 blockade.	ec	18-20	interleukin 17A	Mus musculus	167-172
17297610-3	2007	METHODS: mRNA expression levels of LATS1 and LATS2 were determined by means of real-time PCR assay in 56 locally advanced breast cancers and 15 recurrent breast cancers treated with EC (n = 32) or DOC (n = 39).	ec	182-184	large tumor suppressor kinase 1	Homo sapiens	35-40
17297610-3	2007	METHODS: mRNA expression levels of LATS1 and LATS2 were determined by means of real-time PCR assay in 56 locally advanced breast cancers and 15 recurrent breast cancers treated with EC (n = 32) or DOC (n = 39).	ec	182-184	large tumor suppressor kinase 2	Homo sapiens	45-50
17030351-6	2007	Among EC cases, survivin and COX-2 were strongly positive in 38 (76%) and 30 (60%) patients, respectively.	ec	6-8	prostaglandin-endoperoxide synthase 2	Homo sapiens	29-34
17272829-3	2007	Compared with hA-ITg mice, hA-ITg SR-BI-/- mice had a 4-fold higher total plasma cholesterol concentration, which occurred predominantly in 13-18 nm diameter HDL particles, a significant reduction in plasma esterified cholesterol-total cholesterol (EC/TC) ratio, and significantly lower plasma LCAT activity, suggesting a decrease in LCAT protein.	ec	249-251	scavenger receptor class B member 1	Homo sapiens	34-39
17272829-6	2007	We conclude that the decreased EC/TC ratio in the plasma of hA-ITg SR-BI-/- mice is attributed to a reduction in LCAT reactivity with SM-enriched HDL particles.	ec	31-33	scavenger receptor class B member 1	Homo sapiens	67-72
17046242-5	2007	1,25-Dihydroxyvitamin D(2) potently induced the expression of CALB3 and TRPV6 mRNA with an EC(50) of 0.3 and 1.0nM, whereas 19-nor-1,25-dihydroxyvitamin D(2) was 10-fold less potent than 1,25-dihydroxyvitamin D(2) in inducing CALB3 and TRPV6 mRNA.	ec	91-93	S100 calcium binding protein G	Homo sapiens	62-67
17046242-5	2007	1,25-Dihydroxyvitamin D(2) potently induced the expression of CALB3 and TRPV6 mRNA with an EC(50) of 0.3 and 1.0nM, whereas 19-nor-1,25-dihydroxyvitamin D(2) was 10-fold less potent than 1,25-dihydroxyvitamin D(2) in inducing CALB3 and TRPV6 mRNA.	ec	91-93	transient receptor potential cation channel subfamily V member 6	Homo sapiens	72-77
17272829-6	2007	We conclude that the decreased EC/TC ratio in the plasma of hA-ITg SR-BI-/- mice is attributed to a reduction in LCAT reactivity with SM-enriched HDL particles.	ec	31-33	lecithin cholesterol acyltransferase	Mus musculus	113-117
27407876-13	2006	Overall pregnancy rate of 30% was achieved in the Lap EC group as compared to only 10% in the CC group (p<0.05).	ec	54-56	LAP	Homo sapiens	50-53
16856973-8	2006	There was a linear relationship between EC(50) and inhibitor titer for plasmas with antiporcine FVIII titers ranging from 0.6 to 10 BU per milliliter in both the immediate and the 2 h preincubation assays.	ec	40-42	coagulation factor VIII	Homo sapiens	96-101
16930723-4	2006	EC was induced in wild-type and IFN-gamma-deficient Balb/c mice by active immunization with ragweed (RW) followed by challenge with RW in eye drops.	ec	0-2	interferon gamma	Mus musculus	32-41
16769988-1	2006	PURPOSE: We report on the effects of granulocyte colony-stimulating factor (G-CSF) on hemoglobin (Hb) value in early breast cancer patients receiving high-dose epirubicin and cyclophosphamide (EC) adjuvant treatment.	ec	193-195	colony stimulating factor 3	Homo sapiens	37-74
16769988-1	2006	PURPOSE: We report on the effects of granulocyte colony-stimulating factor (G-CSF) on hemoglobin (Hb) value in early breast cancer patients receiving high-dose epirubicin and cyclophosphamide (EC) adjuvant treatment.	ec	193-195	colony stimulating factor 3	Homo sapiens	76-81
16769988-10	2006	CONCLUSION: Our data suggest that a G-CSF dose-related effect may play a role in worsening anemia in patients receiving adjuvant EC.	ec	129-131	colony stimulating factor 3	Homo sapiens	36-41
17952533-14	2007	Therefore, chemotherapy consisting of CDDP and S-1 may provide a survival benefit for patients with GSCC/EC.	ec	105-107	proteasome 26S subunit, non-ATPase 1	Homo sapiens	47-50
16337670-8	2006	For o,p"-dicofol, the beta-galactosidase induction by (-)-o,p"-dicofol (EC(50): 5.1 x 10(-7)M) was greater than the racemic mixture.	ec	72-74	galactosidase beta 1	Homo sapiens	22-40
16497811-2	2006	Stimulation with ACTH induced production of cAMP with EC(50) values ranging from 7.6-11.9 nM in transient and stable transfectants, respectively.	ec	54-56	proopiomelanocortin	Homo sapiens	17-21
16179399-4	2006	Specifically, we measured the activation of the Akt, GSK-3beta, p70S6K, and ribosomal protein S6 following a single bout of EC in the rat tibialis anterior (TA) muscle.	ec	124-126	AKT serine/threonine kinase 1	Rattus norvegicus	48-51
15882863-2	2005	Based on recent evidence suggesting that the sprouting and branching of capillaries during angiogenesis involves apoptosis, we investigated the involvement of this process in MT1-MMP-dependent morphogenic differentiation of EC into capillary-like structures.	ec	224-226	matrix metallopeptidase 14	Homo sapiens	175-182
18404512-9	2005	Additionally, lower EC(50) concentrations of ATP and UTP triggered migration of cells that was enhanced further with EGF and was inhibited by the tripeptide, RGD.	ec	20-22	epidermal growth factor	Homo sapiens	117-120
15820853-5	2005	Rats exposed to EC for 20 days exhibited increased FMRP immunoreactivity in visual cortex compared with animals housed in standard laboratory caging.	ec	16-18	fragile X messenger ribonucleoprotein 1	Rattus norvegicus	51-55
15820853-6	2005	In the dentate gyrus, animals exposed to EC for 20 days had higher FMRP levels than animals exposed to EC for 5 or 10 days.	ec	41-43	fragile X messenger ribonucleoprotein 1	Rattus norvegicus	67-71
15784546-2	2005	Here we examine the cell surface binding properties of Escherichia coli-derived CdtA-II (CdtA-II(Ec)) and CdtC-II(Ec) and their capacity to provide a binding platform for CdtB-II(Ec).	ec	97-99	corneal dystrophy of Bowman's layer type II (Thiel-Behnke)	Homo sapiens	171-175
15784546-2	2005	Here we examine the cell surface binding properties of Escherichia coli-derived CdtA-II (CdtA-II(Ec)) and CdtC-II(Ec) and their capacity to provide a binding platform for CdtB-II(Ec).	ec	114-116	corneal dystrophy of Bowman's layer type II (Thiel-Behnke)	Homo sapiens	171-175
15784546-3	2005	Using a flow cytometry-based binding assay, we demonstrate that CdtB-II(Ec) binds to the HeLa cell surface in a CdtA-II(Ec)- and CdtC-II(Ec)-dependent manner and that CdtA-II(Ec) and CdtC-II(Ec) compete for the same structure on the HeLa cell surface.	ec	72-74	corneal dystrophy of Bowman's layer type II (Thiel-Behnke)	Homo sapiens	64-68
15784546-3	2005	Using a flow cytometry-based binding assay, we demonstrate that CdtB-II(Ec) binds to the HeLa cell surface in a CdtA-II(Ec)- and CdtC-II(Ec)-dependent manner and that CdtA-II(Ec) and CdtC-II(Ec) compete for the same structure on the HeLa cell surface.	ec	120-122	corneal dystrophy of Bowman's layer type II (Thiel-Behnke)	Homo sapiens	64-68
15784546-3	2005	Using a flow cytometry-based binding assay, we demonstrate that CdtB-II(Ec) binds to the HeLa cell surface in a CdtA-II(Ec)- and CdtC-II(Ec)-dependent manner and that CdtA-II(Ec) and CdtC-II(Ec) compete for the same structure on the HeLa cell surface.	ec	120-122	corneal dystrophy of Bowman's layer type II (Thiel-Behnke)	Homo sapiens	64-68
15784546-3	2005	Using a flow cytometry-based binding assay, we demonstrate that CdtB-II(Ec) binds to the HeLa cell surface in a CdtA-II(Ec)- and CdtC-II(Ec)-dependent manner and that CdtA-II(Ec) and CdtC-II(Ec) compete for the same structure on the HeLa cell surface.	ec	120-122	corneal dystrophy of Bowman's layer type II (Thiel-Behnke)	Homo sapiens	64-68
15784546-3	2005	Using a flow cytometry-based binding assay, we demonstrate that CdtB-II(Ec) binds to the HeLa cell surface in a CdtA-II(Ec)- and CdtC-II(Ec)-dependent manner and that CdtA-II(Ec) and CdtC-II(Ec) compete for the same structure on the HeLa cell surface.	ec	120-122	corneal dystrophy of Bowman's layer type II (Thiel-Behnke)	Homo sapiens	64-68
15388786-5	2005	Of the naturally occurring eicosanoids tested, prostaglandin D(2) (PGD(2); EC(50), 10 nM) was by far the most potent activator of CD203c expression, with other prostanoids having little effect.	ec	75-77	ectonucleotide pyrophosphatase/phosphodiesterase 3	Homo sapiens	130-136
14990132-10	2004	EC(50) of Icariin, sildenafil and papaveine on ICP/MBp were 2.23 micro mol/L, 0.24 micro mol/L and 9.73 micro mol/L respectively.	ec	0-2	myelin basic protein	Rattus norvegicus	51-54
15350011-5	2004	Energy regeneration deteriorated in the grafts preserved by insulin in terms of ATP and EC levels at 24 hours after transplantation.	ec	88-90	insulin	Homo sapiens	60-67
15292386-6	2004	RESULTS: Patients with HER-2/neu-positive tumors had a statistically significantly greater objective response rate than patients with HER-2/neu-negative tumors to treatment with ET (76% versus 50%, respectively; P =.005) but not to treatment with EC (46% versus 33%; P =.130).	ec	247-249	erb-b2 receptor tyrosine kinase 2	Homo sapiens	23-28
15292386-6	2004	RESULTS: Patients with HER-2/neu-positive tumors had a statistically significantly greater objective response rate than patients with HER-2/neu-negative tumors to treatment with ET (76% versus 50%, respectively; P =.005) but not to treatment with EC (46% versus 33%; P =.130).	ec	247-249	erb-b2 receptor tyrosine kinase 2	Homo sapiens	29-32
15001458-13	2004	PPARalpha protects EC from glucose-mediated monocyte adhesion, in part through regulation of IL-6 production.	ec	19-21	peroxisome proliferator activated receptor alpha	Mus musculus	0-9
15001458-13	2004	PPARalpha protects EC from glucose-mediated monocyte adhesion, in part through regulation of IL-6 production.	ec	19-21	interleukin 6	Mus musculus	93-97
14998337-4	2004	The compounds showed a wide range of bioactivities at the frog skin MC1R; e.g. H-d-Phe-c[Hcy-His-d-Phe-Arg-Trp-Cys]-Thr-NH(2) (6, EC(50) = 0.30 nM) and H-d-Phe-c[Cys-His-d-Phe-Arg-Trp-d-Cys]-Thr-NH(2) (8, EC(50) = 0.10 nM).	ec	130-132	melanocortin 1 receptor	Rattus norvegicus	68-72
14757162-3	2004	EC(50) was in the 5-25 microM range, with 2-ClATP behaving as a cytotoxic or cytostatic agent.	ec	0-2	ATP citrate lyase	Homo sapiens	44-49
15218357-8	2004	With regard to progression-free survival, patients with elevated HER-2/neu ECD levels tended to benefit from ET (p = 0.0341), in patients with low levels no difference was observed between EC and ET.	ec	75-77	erb-b2 receptor tyrosine kinase 2	Homo sapiens	71-74
15239993-7	2004	Mean CEA was higher in patients with MCA compared to those with pseudocysts (19,993 +/- 9418 vs. 53 +/- 20 microg/L, P=0.002) and SCA (0.4 +/- 0.1 microg/L; P=0.02), but in the patient with malignant EC, the patient with CPN, and the patient with glucagonoma, CEA was normal.	ec	200-202	CEA cell adhesion molecule 3	Homo sapiens	5-8
14610492-10	2003	CONCLUSION: These results suggest that EC exposure to superantigens skews the immune response toward Th2 cells, leading to allergic skin inflammation and increased IgE synthesis that are characteristic of AD.	ec	39-41	heart and neural crest derivatives expressed 2	Mus musculus	101-104
12940896-4	2003	This CaR became an ideal target for the development of compounds, the calcimimetics, able to amplify the sensitivity of the CaR to ec(Ca2+) suppressing PTH levels with a resultant fall in blood Ca2+.	ec	10-12	parathyroid hormone	Homo sapiens	152-155
11719520-3	2002	ApoE-/- LCAT-/- mice fed the atherogenic diet, compared with apoE-/- mice, had higher concentrations of plasma FC, EC, apoB lipoprotein cholesterol, and phospholipid, and significantly more aortic FC (149 +/- 62 versus 109 +/- 33 mg/g) and EC (101 +/- 23 versus 69 +/- 20 mg/g) than did the apoE-/- mice.	ec	115-117	apolipoprotein E	Mus musculus	0-4
15348671-7	2002	Studies of EC morphology showed the predominant peripheral organization of actin filaments and the formation of distinct leading and trailing cell edges suggesting a motile phenotype of cells when they are seeded on FNG.	ec	11-13	fibrinogen beta chain	Homo sapiens	216-219
12507254-7	2002	17-beta-hydroxy steroid dehydrogenase (17-beta-HSD) and glucose-6-phosphate dehydrogenase (G6PDH), leading to net decrease in serum testosterone concentration in group of rats exposed to one-fifth LC50 of Fen (20% EC) by inhalation (4 hours/day, five days a week) subchronically for three months.	ec	214-216	aldo-keto reductase family 1, member C12	Rattus norvegicus	0-37
12507254-7	2002	17-beta-hydroxy steroid dehydrogenase (17-beta-HSD) and glucose-6-phosphate dehydrogenase (G6PDH), leading to net decrease in serum testosterone concentration in group of rats exposed to one-fifth LC50 of Fen (20% EC) by inhalation (4 hours/day, five days a week) subchronically for three months.	ec	214-216	aldo-keto reductase family 1, member C12	Rattus norvegicus	39-50
12507254-7	2002	17-beta-hydroxy steroid dehydrogenase (17-beta-HSD) and glucose-6-phosphate dehydrogenase (G6PDH), leading to net decrease in serum testosterone concentration in group of rats exposed to one-fifth LC50 of Fen (20% EC) by inhalation (4 hours/day, five days a week) subchronically for three months.	ec	214-216	glucose-6-phosphate dehydrogenase	Rattus norvegicus	56-89
12507254-7	2002	17-beta-hydroxy steroid dehydrogenase (17-beta-HSD) and glucose-6-phosphate dehydrogenase (G6PDH), leading to net decrease in serum testosterone concentration in group of rats exposed to one-fifth LC50 of Fen (20% EC) by inhalation (4 hours/day, five days a week) subchronically for three months.	ec	214-216	glucose-6-phosphate dehydrogenase	Rattus norvegicus	91-96
12811469-6	2003	RESULTS: Interaction of EC with SMC pre-exposed to high glucose concentration yielded changes in endothelial Ca(2+) signalling and polymerization of f-actin in a concentration-dependent and superoxide dismutase (SOD) sensitive manner.	ec	24-26	superoxide dismutase 1	Homo sapiens	190-210
12811469-6	2003	RESULTS: Interaction of EC with SMC pre-exposed to high glucose concentration yielded changes in endothelial Ca(2+) signalling and polymerization of f-actin in a concentration-dependent and superoxide dismutase (SOD) sensitive manner.	ec	24-26	superoxide dismutase 1	Homo sapiens	212-215
12485727-4	2003	When a series of glycine and angiotensin II calibration solutions were derivatized with NDTE followed by CE-EC determination, linear calibration plots resulted with pre-derivatization concentration limits of detection of 500 nM (106 attomoles on-column) and 6 microM (1.275 femtomoles on-column), respectively.	ec	108-110	angiotensinogen	Homo sapiens	29-43
11719520-3	2002	ApoE-/- LCAT-/- mice fed the atherogenic diet, compared with apoE-/- mice, had higher concentrations of plasma FC, EC, apoB lipoprotein cholesterol, and phospholipid, and significantly more aortic FC (149 +/- 62 versus 109 +/- 33 mg/g) and EC (101 +/- 23 versus 69 +/- 20 mg/g) than did the apoE-/- mice.	ec	115-117	lecithin cholesterol acyltransferase	Mus musculus	8-12
11719520-3	2002	ApoE-/- LCAT-/- mice fed the atherogenic diet, compared with apoE-/- mice, had higher concentrations of plasma FC, EC, apoB lipoprotein cholesterol, and phospholipid, and significantly more aortic FC (149 +/- 62 versus 109 +/- 33 mg/g) and EC (101 +/- 23 versus 69 +/- 20 mg/g) than did the apoE-/- mice.	ec	240-242	apolipoprotein E	Mus musculus	0-4
11058598-6	2001	Gel mobility supershift analysis revealed the binding of RARalpha and RXRalpha to oligonucleotides containing both Eb and Ec.	ec	122-124	retinoic acid receptor, alpha	Mus musculus	57-65
11918087-6	2002	EC conditioned medium induced chemoattraction of MM cells, a phenomenon inhibited by anti-MCP-1 antibodies.	ec	0-2	chemokine (C-C motif) ligand 2	Mus musculus	90-95
11335189-7	2001	In an ER alpha-specific, stably transfected human embryonic kidney cell line (293-ER alpha-Luc), the HO-PBDE 4-(2,4,6-tribromophenoxy)phenol was a highly potent estrogen with an EC(50) < 0.1 microM and a maximum 35- to 40-fold induction, which was similar to E(2).	ec	178-180	estrogen receptor 1	Homo sapiens	6-14
11179047-2	2001	PACAP-38 stimulates cAMP production with EC(50) = 0.28 nmol/l (r = 0.92, P < 0.02).	ec	41-43	adenylate cyclase activating polypeptide 1	Rattus norvegicus	0-5
11058598-6	2001	Gel mobility supershift analysis revealed the binding of RARalpha and RXRalpha to oligonucleotides containing both Eb and Ec.	ec	122-124	retinoid X receptor alpha	Mus musculus	70-78
11156580-6	2001	The constrictor response to 10 nM ET-1 was fully reversed by the NO-donor diethylamine NONOate (DEA/NO; EC(50) 2.0 microM, 95% CI: 0.8 - 4.8 microM; n=5).	ec	104-106	endothelin 1	Homo sapiens	34-38
10959741-13	2000	CONCLUSION: EC in pediatric AIDS is a debilitating infection, which develops in the setting of prior OPC, low CD4 counts and previous antibiotics.	ec	12-14	CD4 molecule	Homo sapiens	110-113
11093245-4	2000	It was possible to induce catalase expression by administering exogenous 20-hydroxyecdysone (Ec) in culture at certain stages of development (usually at time points corresponding to previously observed hormone and catalase peaks).	ec	93-95	Catalase	Drosophila melanogaster	26-34
11093245-4	2000	It was possible to induce catalase expression by administering exogenous 20-hydroxyecdysone (Ec) in culture at certain stages of development (usually at time points corresponding to previously observed hormone and catalase peaks).	ec	93-95	Catalase	Drosophila melanogaster	214-222
11093245-5	2000	Experiments with exogenous administration of Ec, cycloheximide, and actinomycin D suggest a complex interplay of factors affecting catalase expression.	ec	45-47	Catalase	Drosophila melanogaster	131-139
11093245-6	2000	In cultured third instar larvae, superinduction of catalase occurred in the presence of both Ec and cycloheximide.	ec	93-95	Catalase	Drosophila melanogaster	51-59
10989133-9	2000	The inhibition by FGF-2 was greater when LH was at a lower concentration (EC(50)<1 ng/ml at LH-20 ng/ml vs. EC(50)>1 ng/ml at LH-50 ng/ml).	ec	74-76	fibroblast growth factor 2	Rattus norvegicus	18-23
11128095-5	2000	The details of the improved EC method are demonstrated in application to the problem of angiotensin converting enzyme (ACE) inhibitors.	ec	28-30	angiotensin I converting enzyme	Homo sapiens	88-117
11128095-5	2000	The details of the improved EC method are demonstrated in application to the problem of angiotensin converting enzyme (ACE) inhibitors.	ec	28-30	angiotensin I converting enzyme	Homo sapiens	119-122
11016880-0	2000	Bradykinin analogues with beta-amino acid substitutions reveal subtle differences in substrate specificity between the endopeptidases EC 3.4.24.15 and EC 3.4.24.16.	ec	134-136	kininogen 1	Homo sapiens	0-10
10864914-6	2000	Treatment of the TC/EC coculture media with anti-TNF-alpha or anti-IL-8 antibodies reduced the media-induced neutrophil adhesion response.	ec	20-22	tumor necrosis factor	Homo sapiens	49-58
10864914-7	2000	The enhanced neutrophil adhesion and the elevated medium levels of TNF-alpha, but not IL-8, were markedly reduced by inserts that prevented direct TC/EC contact and by monoclonal antibodies directed against vascular cell adhesion molecule-1 (VCAM-1) or very late antigen-4 (VLA-4).	ec	150-152	tumor necrosis factor	Homo sapiens	67-76
10864914-7	2000	The enhanced neutrophil adhesion and the elevated medium levels of TNF-alpha, but not IL-8, were markedly reduced by inserts that prevented direct TC/EC contact and by monoclonal antibodies directed against vascular cell adhesion molecule-1 (VCAM-1) or very late antigen-4 (VLA-4).	ec	150-152	vascular cell adhesion molecule 1	Homo sapiens	207-240
10864914-6	2000	Treatment of the TC/EC coculture media with anti-TNF-alpha or anti-IL-8 antibodies reduced the media-induced neutrophil adhesion response.	ec	20-22	C-X-C motif chemokine ligand 8	Homo sapiens	67-71
10096436-3	1999	EC 50 were 10(-8) M for endothelin-1, 10(-8) M for bradykinin and 10(-6) M for serotonin.	ec	0-2	EDN1	Ovis aries	24-36
10193434-10	1999	Binding of sera to EC was competitively inhibited by beta 2-GPI, LPC and oxLDL.	ec	19-21	apolipoprotein H	Homo sapiens	53-63
9785759-12	1998	We know this because the narrowed vessels with their low intraluminal shear and pressure are still capable of large dilation by the NO donor, sodium nitropruside; (2) the antiplatelet effects of EC which are mediated, in part, by the EDRF for ACh are enhanced for 10 to 20 minutes following the transient increase and return of shear within these vessels.	ec	195-197	alpha hemoglobin stabilizing protein	Homo sapiens	234-238
9811473-5	1998	We found that 13 (45%) of 29 cases of EC were hypermethylated in the 5" CpG island of MLH1.	ec	38-40	mutL homolog 1	Homo sapiens	86-90
8826877-5	1996	Plasma ET-1 concentration in the EC group increased remarkably on the first operative day (1st POD), whereas that in the GC group did not.	ec	33-35	endothelin 1	Homo sapiens	7-11
9389785-5	1997	Thus, a significant fraction of i-IEL, such as high-density i-IEL, may partly contribute to induction of apoptosis in the effete i-EC via Fas/FasL interaction.	ec	131-133	Fas ligand (TNF superfamily, member 6)	Mus musculus	142-146
9342676-1	1997	L,L-Ethylene dicysteine (EC) is a ligand used in nuclear medicine for the preparation of 99mTc-L,L-EC, a tracer agent for renal function studies.	ec	25-27	C-C motif chemokine ligand 16	Homo sapiens	97-101
8989255-8	1997	In contrast, plasma ACTH responses after CRH alone were seen in 14 of 17 patients with CD and 2 of 5 patients with EC and, after desmopressin alone, in 12 of 17 with CD and 3 of 5 with EC, thus indicating overlapping responses between the groups and poorer discrimination.	ec	115-117	proopiomelanocortin	Homo sapiens	20-24
8989255-8	1997	In contrast, plasma ACTH responses after CRH alone were seen in 14 of 17 patients with CD and 2 of 5 patients with EC and, after desmopressin alone, in 12 of 17 with CD and 3 of 5 with EC, thus indicating overlapping responses between the groups and poorer discrimination.	ec	115-117	corticotropin releasing hormone	Homo sapiens	41-44
9584098-5	1998	Two of the genes encode proteins, protein kinase A and calmodulin, that have previously been implicated in the signaling pathway leading to EC synthesis and release in other insects.	ec	140-142	Protein kinase, cAMP-dependent, catalytic subunit 1	Drosophila melanogaster	34-65
9217144-9	1997	In distal nerve segments, Western blot analysis revealed that expression of myelin-associated glycoprotein was higher than control for the EC group and lower than control for both the EC-BDNF and EC-BDNF/CNTF groups.	ec	139-141	myelin-associated glycoprotein	Rattus norvegicus	76-106
8826877-6	1996	Plasma levels of hANP in both the EC and GC groups gradually increased until they peaked on the 2nd POD.	ec	34-36	natriuretic peptide A	Homo sapiens	17-21
8826877-7	1996	The increment of plasma hANP secretion for the EC group was significantly higher than that for the GC group on the day of the operation, suggesting that ET-1 stimulated hANP in the EC group.	ec	47-49	natriuretic peptide A	Homo sapiens	24-28
8826877-7	1996	The increment of plasma hANP secretion for the EC group was significantly higher than that for the GC group on the day of the operation, suggesting that ET-1 stimulated hANP in the EC group.	ec	47-49	endothelin 1	Homo sapiens	153-157
8826877-7	1996	The increment of plasma hANP secretion for the EC group was significantly higher than that for the GC group on the day of the operation, suggesting that ET-1 stimulated hANP in the EC group.	ec	47-49	natriuretic peptide A	Homo sapiens	169-173
8826877-7	1996	The increment of plasma hANP secretion for the EC group was significantly higher than that for the GC group on the day of the operation, suggesting that ET-1 stimulated hANP in the EC group.	ec	181-183	natriuretic peptide A	Homo sapiens	24-28
8826877-7	1996	The increment of plasma hANP secretion for the EC group was significantly higher than that for the GC group on the day of the operation, suggesting that ET-1 stimulated hANP in the EC group.	ec	181-183	endothelin 1	Homo sapiens	153-157
8826877-7	1996	The increment of plasma hANP secretion for the EC group was significantly higher than that for the GC group on the day of the operation, suggesting that ET-1 stimulated hANP in the EC group.	ec	181-183	natriuretic peptide A	Homo sapiens	169-173
8675173-8	1996	Flow cytometric analysis showed a significant HSE heterogeneity in mannose receptor-mediated endocytosis in response to IL-1beta treatment: type I endothelial cells (EC-I, defined by their small size and high cytoplasmic density) significantly (P < .01) increased OVA-FITC uptake compared with type II endothelial cells (EC-II, defined by their large size and low cytoplasmic density).	ec	166-168	interleukin 1 beta	Mus musculus	120-128