PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
28576325-7	2017	Transcriptomic analyses indicate that the beneficial effect of nAl2O3 was related to an increase in the transcription of several genes involved in root growth as well as in root nutrient uptake (e.g., up-regulation of the root hair-specific gene family and root development genes, POLARIS protein).	nal2o3	63-69	polari	Arabidopsis thaliana	281-288
31277021-0	2019	Antagonistic effect of vitamin E on nAl2O3-induced exacerbation of Th2 and Th17-mediated allergic asthma via oxidative stress.	nal2o3	36-42	heart and neural crest derivatives expressed 2	Mus musculus	67-70
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	interleukin 1 beta	Mus musculus	141-149
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	interleukin 6	Mus musculus	154-158
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	GATA binding protein 3	Mus musculus	221-227
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	interferon gamma	Mus musculus	266-275
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	interleukin 10	Mus musculus	280-285
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	interleukin 4	Mus musculus	313-317
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	interleukin 17A	Mus musculus	322-328
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	negative elongation factor complex member C/D, Th1l	Mus musculus	360-363
31277021-6	2019	Results revealed that nAl2O3 could increase ROS levels and decrease GSH levels in lung tissue, promote the increases of the T-IgE, TGF-beta, IL-1beta and IL-6 levels, stimulate the overexpression of transcription factors GATA-3 and RORgammat, decrease the levels of IFN-gamma and IL-10 and increase the levels of IL-4 and IL-17A, resulting in the imbalance of Th1/Th2 and Treg/Th17 immune responses.	nal2o3	22-28	heart and neural crest derivatives expressed 2	Mus musculus	364-367
31277021-8	2019	The study displayed that exposure of nAl2O3 deteriorated allergic asthma through promoting the imbalances of Th1/Th2 and Treg/Th17.	nal2o3	37-43	negative elongation factor complex member C/D, Th1l	Mus musculus	109-112
31277021-8	2019	The study displayed that exposure of nAl2O3 deteriorated allergic asthma through promoting the imbalances of Th1/Th2 and Treg/Th17.	nal2o3	37-43	heart and neural crest derivatives expressed 2	Mus musculus	113-116