PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 31440419-8 2019 Innovation: Wounds of db/db mice treated with GQ-11 exhibited faster wound closure and re-epithelization, increased collagen deposition, and less Mac-3 staining compared with vehicle, providing a new approach to treatment of diabetic wound healing to prevent complications. gq-11 46-51 lysosomal-associated membrane protein 2 Mus musculus 146-151 29453462-0 2018 GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr-/- mice. gq-11 0-5 peroxisome proliferator activated receptor alpha Mus musculus 13-17 29453462-0 2018 GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr-/- mice. gq-11 0-5 low density lipoprotein receptor Mus musculus 76-80 29453462-2 2018 OBJECTIVE: To assess the effects of a new thiazolidine compound-GQ-11-on obesity and insulin resistance induced by a diabetogenic diet in LDL receptor-deficient (LDLr-/-) mice. gq-11 64-69 low density lipoprotein receptor Mus musculus 162-170 29453462-7 2018 RESULTS: GQ-11 showed partial agonism to PPARgamma and PPARalpha. gq-11 9-14 peroxisome proliferator activated receptor gamma Mus musculus 41-50 29453462-7 2018 RESULTS: GQ-11 showed partial agonism to PPARgamma and PPARalpha. gq-11 9-14 peroxisome proliferator activated receptor alpha Mus musculus 55-64 29453462-9 2018 In addition, GQ-11 restored adipokine imbalance induced by a diabetogenic diet and enhanced Glut-4 expression in the adipose tissue. gq-11 13-18 solute carrier family 2 (facilitated glucose transporter), member 4 Mus musculus 92-98 29453462-11 2018 Furthermore, GQ-11 reduced triglycerides and VLDL cholesterol and increased HDL-cholesterol by upregulation of Apoa1 and Abca1 gene expression in the liver. gq-11 13-18 apolipoprotein A-I Mus musculus 111-116 29453462-11 2018 Furthermore, GQ-11 reduced triglycerides and VLDL cholesterol and increased HDL-cholesterol by upregulation of Apoa1 and Abca1 gene expression in the liver. gq-11 13-18 ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus 121-126 29453462-12 2018 CONCLUSION: GQ-11 is a partial/dual PPARalpha/gamma agonist that demonstrates anti-diabetic effects. gq-11 12-17 peroxisome proliferator activated receptor alpha Mus musculus 36-45