PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11952331-6	2002	The alpha-hydroxylation of NHMOR at either C-3 or C-5 to give glyoxal or glycolaldehyde, respectively, occurs at respective rates 3-6 times that of the alpha-hydroxylation of NDELA.	N-nitrosodiethanolamine	175-180	complement C3	Rattus norvegicus	43-46
11952331-6	2002	The alpha-hydroxylation of NHMOR at either C-3 or C-5 to give glyoxal or glycolaldehyde, respectively, occurs at respective rates 3-6 times that of the alpha-hydroxylation of NDELA.	N-nitrosodiethanolamine	175-180	complement C5	Rattus norvegicus	50-53
8547828-0	1995	Variation in the expression of p53, c-myc, and bcl-2 oncoproteins in individual patient cultures of normal urothelium exposed to cobalt 60 gamma-rays and N-nitrosodiethanolamine.	N-nitrosodiethanolamine	154-177	tumor protein p53	Homo sapiens	31-34
8146306-0	1994	Induction of stable p53 oncoprotein and of c-myc overexpression in cultured normal human uroepithelium by radiation and N-nitrosodiethanolamine.	N-nitrosodiethanolamine	120-143	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	43-48
1687902-6	1991	Clear dose-dependent initiating activity of NDELA was observed in terms of development of glutathione S-transferase placental form (GST-P) positive liver cell foci, this being more apparent with PB promotion than with 2-AAF where the enhancing regimen itself caused multiple lesion development.	N-nitrosodiethanolamine	44-49	glutathione S-transferase pi 1	Rattus norvegicus	90-137
3009488-1	1986	The potent carcinogen N-nitrosodiethanolamine (NDELA) which is nonmutagenic in standard modifications of the S. typhimurium/mammalian microsome assay, can be activated effectively by alcohol dehydrogenase/NAD (ADH/NAD) to intermediates which are directly mutagenic in strains TA 98 and TA 100.	N-nitrosodiethanolamine	22-45	alcohol dehydrogenase 1A (class I), alpha polypeptide	Homo sapiens	183-217
3009488-1	1986	The potent carcinogen N-nitrosodiethanolamine (NDELA) which is nonmutagenic in standard modifications of the S. typhimurium/mammalian microsome assay, can be activated effectively by alcohol dehydrogenase/NAD (ADH/NAD) to intermediates which are directly mutagenic in strains TA 98 and TA 100.	N-nitrosodiethanolamine	47-52	alcohol dehydrogenase 1A (class I), alpha polypeptide	Homo sapiens	183-217
29473797-4	2018	At high concentrations of 100 or 1000 microg/ml, Vit E significantly decreased residual NDELA compared with control levels under acidic pH 2, but not under basic pH 6.	N-nitrosodiethanolamine	88-93	vitrin	Homo sapiens	49-52
23833673-7	2013	The expression of BRCA2 and RAD51 was demonstrated to be inhibited by NDEA treatment but upregulated by NDELA or NDPA treatment.	N-nitrosodiethanolamine	104-109	BRCA2 DNA repair associated	Homo sapiens	18-23
23833673-7	2013	The expression of BRCA2 and RAD51 was demonstrated to be inhibited by NDEA treatment but upregulated by NDELA or NDPA treatment.	N-nitrosodiethanolamine	104-109	RAD51 recombinase	Homo sapiens	28-33
2808483-0	1989	Increased mutagenicity of N-nitrosodiethanolamine in human lymphocyte cultures after activation by alcohol dehydrogenase.	N-nitrosodiethanolamine	26-49	aldo-keto reductase family 1 member A1	Homo sapiens	99-120
2808483-1	1989	The effect of alcohol dehydrogenase (ADH/NAD) from yeast and horse liver was tested on the induction of chromosomal mutations and sister chromatid exchanges (SCE) by N-nitrosodiethanolamine (NDELA) in human lymphocyte cultures.	N-nitrosodiethanolamine	166-189	aldo-keto reductase family 1 member A1	Homo sapiens	14-35
2808483-1	1989	The effect of alcohol dehydrogenase (ADH/NAD) from yeast and horse liver was tested on the induction of chromosomal mutations and sister chromatid exchanges (SCE) by N-nitrosodiethanolamine (NDELA) in human lymphocyte cultures.	N-nitrosodiethanolamine	191-196	aldo-keto reductase family 1 member A1	Homo sapiens	14-35
18616954-4	2008	Previous work indicated that cytochrome P450 (CYP) 2E1, alcohol dehydrogenases and sulphotransferases (SULTs) can convert NDELA into reactive metabolites.	N-nitrosodiethanolamine	122-127	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	29-54
18616954-5	2008	We report here that NDELA induces concentration-dependent gene mutations (at the hprt locus) in V79-hCYP2E1-hSULT1A1 cells, engineered for expression of human CYP2E1 and human SULT1A1, but is inactive in parental V79 cells.	N-nitrosodiethanolamine	20-25	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	100-107
18616954-5	2008	We report here that NDELA induces concentration-dependent gene mutations (at the hprt locus) in V79-hCYP2E1-hSULT1A1 cells, engineered for expression of human CYP2E1 and human SULT1A1, but is inactive in parental V79 cells.	N-nitrosodiethanolamine	20-25	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	101-107
18616954-5	2008	We report here that NDELA induces concentration-dependent gene mutations (at the hprt locus) in V79-hCYP2E1-hSULT1A1 cells, engineered for expression of human CYP2E1 and human SULT1A1, but is inactive in parental V79 cells.	N-nitrosodiethanolamine	20-25	sulfotransferase family 1A member 1	Homo sapiens	109-116