PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
31515780-8	2019	CONCLUSION: Mutations of the CYP17A1 gene probably underlie the pathogenesis of 17-OHD, for which c.985_987delTACinsAA(Y329Kfs) is the most common.	17-ohd	80-86	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	29-36
19040066-1	2008	OBJECTIVE: To investigate the molecular defects of CYP17A1 gene in a pedigree with two 46,XY patients suffering from 17alpha-hydroxylase deficiency (17-OHD) and explore the steroid biosynthetic difference in carriers of 17-OHD before and after adrenocorticotrophic hormone (ACTH) test.	17-ohd	149-155	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	51-58
19040066-1	2008	OBJECTIVE: To investigate the molecular defects of CYP17A1 gene in a pedigree with two 46,XY patients suffering from 17alpha-hydroxylase deficiency (17-OHD) and explore the steroid biosynthetic difference in carriers of 17-OHD before and after adrenocorticotrophic hormone (ACTH) test.	17-ohd	220-226	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	51-58
19040066-7	2008	CONCLUSION: 17-OHD in this family was caused by CYP17A1 mutation (TAC329AA); some hormonal response to ACTH stimulation was abnormal in carriers.	17-ohd	12-18	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	48-55
19040066-7	2008	CONCLUSION: 17-OHD in this family was caused by CYP17A1 mutation (TAC329AA); some hormonal response to ACTH stimulation was abnormal in carriers.	17-ohd	12-18	proopiomelanocortin	Homo sapiens	103-107
31695722-2	2019	The 17alpha-hydroxylase/17,20-lyase deficiency (17-OHD) is an uncommon form of CAH caused by variants in the CYP17A1 gene.	17-ohd	48-54	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	109-116
31695722-3	2019	Aims: We report a novel compound heterozygous CYP17A1 variant and its association with the pathogenesis of 17-OHD.	17-ohd	107-113	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	46-53
31695722-14	2019	Conclusions: These results suggest that the compound heterozygous variant of c.1304T > C and c.1228delG of the CYP17A1 gene can lead to 17-OHD.	17-ohd	136-142	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	111-118
30695673-2	2018	17-OHD is caused by mutations in the cytochrome P450c17 gene (CYP17A1), and characterized by hypertension, hypokalemia, female sexual infantilism, or male pseudohermaphroditism.	17-ohd	0-6	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	37-55
30614301-1	2019	17alpha-Hydroxylase/17,20-lyase deficiency (17-OHD) is a rare disease caused by mutations of the CYP17A1 gene.	17-ohd	44-50	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	97-104
30614301-12	2019	For the first time, we report a 17-OHD case accompanied by SCFE, AML, and a novel mutation site in the CYP17A1 gene.	17-ohd	32-38	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	103-110
30695673-2	2018	17-OHD is caused by mutations in the cytochrome P450c17 gene (CYP17A1), and characterized by hypertension, hypokalemia, female sexual infantilism, or male pseudohermaphroditism.	17-ohd	0-6	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	62-69
30695673-11	2018	In conclusion, we discovered two novel heterozygous CYP17A1 mutations Ile381Thr (c.1142T>C) and Ser168del (c.503_505delCCT) in a Chinese patient with 17-OHD.	17-ohd	153-159	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	52-59