PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11207750-14	1999	Under anaerobic conditions, strain CKB can dismutate chlorite into chloride and O2, and is only the second organism shown to be capable of this metabolism.	chlorite	53-61	creatine kinase B	Homo sapiens	35-38
9721393-3	1998	A new preoperative skin antiseptic has been developed (Alcide Corporation, Redmond, Wash) that involves the mixture of a 0.1% sodium chlorite formulation and an activating preparation of 0.5% mandelic acid to produce chlorous acid and other antimicrobial degradation products.	chlorite	126-141	WASP family homolog 6, pseudogene	Homo sapiens	84-88
9154205-11	1997	Only use of sodium chlorite-lactic acid predip was significantly associated with a decrease in SCC in herds without S agalactiae mastitis.	chlorite	12-27	SCC	Bos taurus	95-98
16668525-2	1991	Chlorate is a substrate for the enzyme nitrate reductase (NR), which reduces chlorate to the toxic chlorite.	chlorite	99-107	nitrate reductase 1	Arabidopsis thaliana	39-56
16668525-2	1991	Chlorate is a substrate for the enzyme nitrate reductase (NR), which reduces chlorate to the toxic chlorite.	chlorite	99-107	nitrate reductase 1	Arabidopsis thaliana	58-60
16668525-10	1991	The low levels of NR protein and activity may be due to inactivation of NR by chlorite, leading to rapid degradation of the enzyme.	chlorite	78-86	nitrate reductase 1	Arabidopsis thaliana	18-20
16668525-10	1991	The low levels of NR protein and activity may be due to inactivation of NR by chlorite, leading to rapid degradation of the enzyme.	chlorite	78-86	nitrate reductase 1	Arabidopsis thaliana	72-74
34985218-1	2022	Adsorbable organic halogens (AOX) are often introduced or produced in textile and dyeing processes, such as the chlorination shrink proof process of wool, the bleaching process by sodium hypochlorite and chlorite, the dry-cleaning process by chlorinated solvent, etc.	chlorite	204-212	acyl-CoA oxidase 1	Homo sapiens	29-32
34303235-1	2021	This study is the first that monitored the presence and levels of chlorite, chlorate and bromate in tap drinking water of Egypt.	chlorite	66-74	nuclear RNA export factor 1	Homo sapiens	100-103
7462905-3	1980	Chlorite, a by-product of chlorine dioxide disinfection of water, produced decreases in GSH and G6PD activity, while increasing methemoglobin levels markedly over red cells with normal G6PD activity.	chlorite	0-8	glucose-6-phosphate dehydrogenase	Homo sapiens	96-100
7462905-3	1980	Chlorite, a by-product of chlorine dioxide disinfection of water, produced decreases in GSH and G6PD activity, while increasing methemoglobin levels markedly over red cells with normal G6PD activity.	chlorite	0-8	hemoglobin subunit gamma 2	Homo sapiens	128-141
7462905-3	1980	Chlorite, a by-product of chlorine dioxide disinfection of water, produced decreases in GSH and G6PD activity, while increasing methemoglobin levels markedly over red cells with normal G6PD activity.	chlorite	0-8	glucose-6-phosphate dehydrogenase	Homo sapiens	185-189
7462914-2	1980	Levels of methemoglobin are significantly greater and GSH levels significantly lower in the G6PD deficient cells than in normal cells after chlorite exposure.	chlorite	140-148	hemoglobin subunit gamma 2	Homo sapiens	10-23
7462915-3	1980	Chlorite (a product formed from chlorine dioxide disinfection) produced increases in MCV (mean corpuscular volume); osmotic fragility; G6PD (glucose-6-phosphate dehydrogenase) activity; and the number of acanthocytes at exposure to 100 ppm, but not 1.0 or 10.0 ppm.	chlorite	0-8	glucose-6-phosphate dehydrogenase 2	Mus musculus	135-139
7462915-3	1980	Chlorite (a product formed from chlorine dioxide disinfection) produced increases in MCV (mean corpuscular volume); osmotic fragility; G6PD (glucose-6-phosphate dehydrogenase) activity; and the number of acanthocytes at exposure to 100 ppm, but not 1.0 or 10.0 ppm.	chlorite	0-8	glucose-6-phosphate dehydrogenase 2	Mus musculus	141-174
753950-3	1978	However, chlorine dioxide is a strong oxidant that forms significant amounts of chlorite when added to potable water supplies, and chlorite is similar to nitrite in its molecular structure and may be similar in its mechanism of methemoglobin production.	chlorite	131-139	hemoglobin subunit gamma 2	Homo sapiens	228-241
547025-2	1979	Cl02 and metabolites, chlorite (Cl0-2) and chlorate (Cl0-3) in drinking water produced decreases in rat and chicken blood GSH.	chlorite	22-30	calpain 8	Rattus norvegicus	32-37
510241-6	1979	Preliminary results indicate that the mouse strain with low G-6-PD activity is markedly more susceptible to sodium chlorite than mice of the high G-6-PD strain.	chlorite	108-123	glucose-6-phosphate dehydrogenase 2	Mus musculus	60-66
510241-7	1979	This differential susceptibility to sodium chlorite toxicity between the high and low G-6-PD mouse strains suggests that further research designed to validate the efficacy of this mouse model as a predictor of the human situation is warranted.	chlorite	36-51	glucose-6-phosphate dehydrogenase 2	Mus musculus	86-92
17760011-0	1948	Sodium Chlorite as an Aid in Paleobotanical and Anatomical Study of Plant Tissues.	chlorite	0-15	activation induced cytidine deaminase	Homo sapiens	22-25
173555-0	1976	The involvement of cytochrome P-450 in hepatic microsomal steroid hydroxylation reactions supported by sodium periodate, sodium chlorite, and organic hydroperoxides.	chlorite	121-136	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	19-35
173555-13	1976	It is proposed that NaIO4, NaClO2, and organic hydroperoxides promote steroid hydroxylation by forming a transient ferryl ion (compound I) of cytochrome P-450 which may be the common intermediate hydroxylating species involved in hydroxylations catalyzed by cytochrome P-450.	chlorite	27-33	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	142-158
173555-13	1976	It is proposed that NaIO4, NaClO2, and organic hydroperoxides promote steroid hydroxylation by forming a transient ferryl ion (compound I) of cytochrome P-450 which may be the common intermediate hydroxylating species involved in hydroxylations catalyzed by cytochrome P-450.	chlorite	27-33	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	258-274
28458145-0	2017	Chlorite reactivity with myoglobin: Analogy with peroxide and nitrite chemistry?	chlorite	0-8	myoglobin	Homo sapiens	25-34
32182191-2	2020	It was confirmed that the injection of sodium chlorite upstream the FGD absorber oxidize NO to NO2, Hg0 to Hg2+ and enhancing NOx and HgT removal efficiency from exhaust gas in FGD absorber.	chlorite	39-54	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	107-110
28458145-1	2017	Stopped-flow UV-vis data allow for the first time direct spectroscopic detection of a ferryl species during the reaction of met myoglobin (Mb) with chlorite, analogous to what is observed in the reaction with peroxides.	chlorite	148-156	myoglobin	Homo sapiens	128-137
27478981-7	2017	Methemoglobin content was tremendously increased, by 5-52 fold when compared to control, while methemoglobin reductase activity decreased (-17 to -93%) upon NaClO2 treatment.	chlorite	157-163	hemoglobin subunit gamma 2	Homo sapiens	0-13
27864634-0	2017	Reactions of aquacobalamin and cob(II)alamin with chlorite and chlorine dioxide.	chlorite	50-58	metabolism of cobalamin associated B	Homo sapiens	17-20
27864634-1	2017	Reactions of aquacobalamin (H2O-Cbl(III)) and its one-electron reduced form (cob(II)alamin, Cbl(II)) with chlorite (ClO2-) and chlorine dioxide (ClO 2  ) were studied by conventional and stopped-flow UV-Vis spectroscopies and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS).	chlorite	106-114	Cbl proto-oncogene	Homo sapiens	32-35
27864634-1	2017	Reactions of aquacobalamin (H2O-Cbl(III)) and its one-electron reduced form (cob(II)alamin, Cbl(II)) with chlorite (ClO2-) and chlorine dioxide (ClO 2  ) were studied by conventional and stopped-flow UV-Vis spectroscopies and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS).	chlorite	106-114	metabolism of cobalamin associated B	Homo sapiens	17-20
27864634-1	2017	Reactions of aquacobalamin (H2O-Cbl(III)) and its one-electron reduced form (cob(II)alamin, Cbl(II)) with chlorite (ClO2-) and chlorine dioxide (ClO 2  ) were studied by conventional and stopped-flow UV-Vis spectroscopies and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS).	chlorite	106-114	Cbl proto-oncogene	Homo sapiens	92-95
27864634-3	2017	The proposed mechanism of chlorite reduction involves formation of OCl- that modifies the corrin ring during the course of reaction with Cbl(II).	chlorite	26-34	Cbl proto-oncogene	Homo sapiens	137-140
27478981-7	2017	Methemoglobin content was tremendously increased, by 5-52 fold when compared to control, while methemoglobin reductase activity decreased (-17 to -93%) upon NaClO2 treatment.	chlorite	157-163	hemoglobin subunit gamma 2	Homo sapiens	95-108
28176842-6	2017	Based on the knowledge of sediment provenances, we suggest that these two proxies in the South China Sea are linked to the East Asian summer monsoon evolution with different mechanisms, which are (1) contemporaneous chemical weathering intensity in Luzon for smectite/(illite + chlorite) ratio and (2) river denudation intensity for K2O/Al2O3 ratio of bulk sediment.	chlorite	278-286	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	101-104
26391926-0	2015	Interaction of the chlorite-based drug WF10 and chlorite with hemoglobin, methemoglobin and ferryl hemoglobin.	chlorite	19-27	hemoglobin subunit gamma 2	Homo sapiens	74-87
28129378-3	2017	Here we present a high-resolution record of fine-grained eastern Saharan dust from the Eastern Mediterranean Sea spanning the last 180 kyr, which is based on the clay mineral composition of the marine sediments, especially the kaolinite/chlorite ratio.	chlorite	237-245	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	109-112
26391926-0	2015	Interaction of the chlorite-based drug WF10 and chlorite with hemoglobin, methemoglobin and ferryl hemoglobin.	chlorite	48-56	hemoglobin subunit gamma 2	Homo sapiens	74-87
26391926-3	2015	Methemoglobin is also formed upon the interaction of ferryl hemoglobin and WF10/chlorite.	chlorite	80-88	hemoglobin subunit gamma 2	Homo sapiens	0-13
26391926-6	2015	A considerable higher rate (6600 M(-1)s(-1)) is measured between the chlorite components of WF10 and ferryl hemoglobin after formation of the latter species from methemoglobin.	chlorite	69-77	hemoglobin subunit gamma 2	Homo sapiens	162-175
26391926-7	2015	WF10/chlorite inactivates also methemoglobin as evidenced by the continuous decrease of the Soret band and all other absorbances with a rate of 8.3 M(-1)s(-1).	chlorite	5-13	hemoglobin subunit gamma 2	Homo sapiens	31-44
26002730-6	2015	CYP enzymes utilize hydroperoxides, peracids, perborate, percarbonate, periodate, chlorite, iodosobenzene and N-oxides as surrogate oxygen atom donors to oxygenate substrates via the shunt pathway in the absence of NAD(P)H/O2 and reduction-oxidation (redox) auxiliary proteins.	chlorite	82-90	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-3
25093679-2	2014	We previously showed that chlorite-oxidized oxyamylose/COAM binds the neutrophil chemokine GCP-2/CXCL6.	chlorite	26-34	chemokine (C-X-C motif) ligand 5	Mus musculus	91-96
25093679-2	2014	We previously showed that chlorite-oxidized oxyamylose/COAM binds the neutrophil chemokine GCP-2/CXCL6.	chlorite	26-34	chemokine (C-X-C motif) ligand 5	Mus musculus	97-102
24632343-2	2014	In contrast to plant peroxidases, like horseradish peroxidase (HRP), the mammalian counterparts myeloperoxidase (MPO) and lactoperoxidase (LPO) are rapidly and irreversibly inactivated by chlorite in the micromolar concentration range.	chlorite	188-196	myeloperoxidase	Homo sapiens	96-111
24632343-2	2014	In contrast to plant peroxidases, like horseradish peroxidase (HRP), the mammalian counterparts myeloperoxidase (MPO) and lactoperoxidase (LPO) are rapidly and irreversibly inactivated by chlorite in the micromolar concentration range.	chlorite	188-196	myeloperoxidase	Homo sapiens	113-116
24632343-2	2014	In contrast to plant peroxidases, like horseradish peroxidase (HRP), the mammalian counterparts myeloperoxidase (MPO) and lactoperoxidase (LPO) are rapidly and irreversibly inactivated by chlorite in the micromolar concentration range.	chlorite	188-196	lactoperoxidase	Homo sapiens	122-137
24632343-2	2014	In contrast to plant peroxidases, like horseradish peroxidase (HRP), the mammalian counterparts myeloperoxidase (MPO) and lactoperoxidase (LPO) are rapidly and irreversibly inactivated by chlorite in the micromolar concentration range.	chlorite	188-196	lactoperoxidase	Homo sapiens	139-142
24632343-3	2014	Chlorite acts as efficient one-electron donor for Compound I and Compound II of MPO and LPO and reacts with the corresponding ferric resting states in a biphasic manner.	chlorite	0-8	myeloperoxidase	Homo sapiens	80-83
24632343-3	2014	Chlorite acts as efficient one-electron donor for Compound I and Compound II of MPO and LPO and reacts with the corresponding ferric resting states in a biphasic manner.	chlorite	0-8	lactoperoxidase	Homo sapiens	88-91
24632343-4	2014	The first (rapid) phase is shown to correspond to the formation of a MPO-chlorite high-spin complex, whereas during the second (slower) phase degradation of the prosthetic group was observed.	chlorite	73-81	myeloperoxidase	Homo sapiens	69-72
23695836-17	2013	The ability of strain CAB to oxidize catechol via the oxygenase-dependent meta-cleavage pathway in the absence of external oxygen by using the biogenic oxygen produced from the dismutation of chlorite provides a valuable model for understanding the anaerobic degradation of a broad diversity of xenobiotics which are recalcitrant to anaerobic metabolism but labile to oxygenase-dependent mechanisms.	chlorite	192-200	neural proliferation, differentiation and control 1	Homo sapiens	22-25
24659456-3	2014	We then introduced NO2 into the gas mixture as a radical scavenger and determined that the chlorinated species generated by the reaction of SO2 with NaClO2(s) are OClO, Cl, ClO, and Cl2.	chlorite	149-155	endogenous retrovirus group W member 5	Homo sapiens	182-185
21905903-1	2013	The aim of this study was to examine the bactericidal effects and bactericidal time of an acidified sodium chlorite compound gel (ASC-Gel) on bacteria isolated from the peri-implant sulci of 10 patients who received implants 3-27 years previously, and the depth of each peri-implant sulcus was 5 mm or less.	chlorite	100-115	PYD and CARD domain containing	Homo sapiens	130-133
23695836-9	2013	Further, under anoxic growth conditions strain CAB utilized the biogenic oxygen produced as a result of chlorite dismutation to oxidize catechol via the meta-cleavage pathway of aerobic catechol degradation and the catechol 2,3-dioxygenase enzyme.	chlorite	104-112	neural proliferation, differentiation and control 1	Homo sapiens	47-50
22578809-10	2012	CONCLUSIONS: This was the first study showing an excess risk of different congenital anomalies related to chlorite and chlorate exposure via drinking water: further research is needed to confirm the observed relationships in large datasets, specifically for chlorate, an unregulated DBP.	chlorite	106-114	D-box binding PAR bZIP transcription factor	Homo sapiens	283-286
18951614-5	2008	Mineral quantification based on stoichiometric analysis and quantitative powder X-ray diffraction (XRD) documents progressive dissolution of chlorite (CCa-2 ripidolite) and two varieties of smectite (SapCa-2 saponite and SWa-1 nontronite) during steps 1-3 of the BCR procedure.	chlorite	141-149	crystallin beta B2	Homo sapiens	151-156
22608440-5	2012	This sensor is intended to fulfill the daily monitoring requirements of the EPA DBP regulations for chlorite ion.	chlorite	100-108	D-box binding PAR bZIP transcription factor	Homo sapiens	80-83
16833417-3	2005	In excess chlorite concentrations the reaction stoichiometry involves the complete desulfurization of PTU to yield a urea residue and sulfate: 2ClO2- + PhN(H)CSNH2 + H2O --> SO4(2-) + PhN(H)CONH2 + 2Cl- + 2H+.	chlorite	10-18	carbamoyl-phosphate synthase 1	Homo sapiens	152-155
19127746-0	2006	Inhibition of apple polyphenol oxidase activity by sodium chlorite.	chlorite	51-66	polyphenol oxidase, chloroplastic	Malus domestica	20-38
19127746-7	2006	Preincubation of PPO with 8 mM SC for 8 min caused a maximum of 46% activity reduction compared to noninhibited control.	chlorite	31-33	polyphenol oxidase, chloroplastic	Malus domestica	17-20
16833417-3	2005	In excess chlorite concentrations the reaction stoichiometry involves the complete desulfurization of PTU to yield a urea residue and sulfate: 2ClO2- + PhN(H)CSNH2 + H2O --> SO4(2-) + PhN(H)CONH2 + 2Cl- + 2H+.	chlorite	10-18	carbamoyl-phosphate synthase 1	Homo sapiens	187-190