PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 31984273-3 2020 Herein, we report the synthesis of new substituted variants of Sondheimer dialkyne and their application in the stapling of p53-based diazido peptides to generate potent stapled peptide-based inhibitors of the oncogenic p53-MDM2 interaction. 2,8-diazidoadenosine 5'-triphosphate 134-141 tumor protein p53 Homo sapiens 124-127 31984273-3 2020 Herein, we report the synthesis of new substituted variants of Sondheimer dialkyne and their application in the stapling of p53-based diazido peptides to generate potent stapled peptide-based inhibitors of the oncogenic p53-MDM2 interaction. 2,8-diazidoadenosine 5'-triphosphate 134-141 tumor protein p53 Homo sapiens 220-223 31984273-3 2020 Herein, we report the synthesis of new substituted variants of Sondheimer dialkyne and their application in the stapling of p53-based diazido peptides to generate potent stapled peptide-based inhibitors of the oncogenic p53-MDM2 interaction. 2,8-diazidoadenosine 5'-triphosphate 134-141 MDM2 proto-oncogene Homo sapiens 224-228