PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11784807-3	2002	In this study, we sought to identify the optimal targeting sites in GPi and STN for reversal of parkinsonian signs through a series of reversible injections of the GABA(A) agonist muscimol in these nuclei in parkinsonian primates.	Muscimol	180-188	glucose-6-phosphate isomerase	Homo sapiens	68-71
11826037-7	2002	Although muscimol injections into the OPN region produced little change in the optimal vector, they did increase mean saccade duration by 25 to 192.8% and decrease mean saccade peak velocity by 20.5 to 69.8%.	Muscimol	9-17	secreted phosphoprotein 1	Homo sapiens	38-41
11427701-4	2001	In females, muscimol treatment primarily decreased the phosphorylation of cAMP response element binding protein (CREB) within the hypothalamus and the CA1 region of the hippocampus.	Muscimol	12-20	cAMP responsive element binding protein 1	Rattus norvegicus	74-111
11716980-1	2001	To determine the involvement of the medial prefrontal cortex (mPFC) in operant-type delayed alternation, microinjections of muscimol into the mPFC were used for temporal inactivation during behavioral tests in rats.	Muscimol	124-132	complement factor properdin	Mus musculus	142-146
11584925-5	2001	For sexually naive mice, greater lordosis on initial sexual experience corresponded to greater concentrations of plasma and central progestins and increased central binding of a GABAA agonist, muscimol, compared with that seen in mice with lower lordosis on initial mating.	Muscimol	193-201	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	178-183
11551834-6	2001	GABA(A) receptor agonist, muscimol, dose dependently inhibited epidermal growth factor (EGF) induced DNA synthesis and enhanced the transforming growth factor beta1 (TGFbeta1) mediated DNA synthesis suppression in primary hepatocyte cultures.	Muscimol	26-34	epidermal growth factor like 1	Rattus norvegicus	63-86
11551834-6	2001	GABA(A) receptor agonist, muscimol, dose dependently inhibited epidermal growth factor (EGF) induced DNA synthesis and enhanced the transforming growth factor beta1 (TGFbeta1) mediated DNA synthesis suppression in primary hepatocyte cultures.	Muscimol	26-34	epidermal growth factor like 1	Rattus norvegicus	88-91
11551834-6	2001	GABA(A) receptor agonist, muscimol, dose dependently inhibited epidermal growth factor (EGF) induced DNA synthesis and enhanced the transforming growth factor beta1 (TGFbeta1) mediated DNA synthesis suppression in primary hepatocyte cultures.	Muscimol	26-34	transforming growth factor, beta 1	Rattus norvegicus	132-164
11551834-6	2001	GABA(A) receptor agonist, muscimol, dose dependently inhibited epidermal growth factor (EGF) induced DNA synthesis and enhanced the transforming growth factor beta1 (TGFbeta1) mediated DNA synthesis suppression in primary hepatocyte cultures.	Muscimol	26-34	transforming growth factor, beta 1	Rattus norvegicus	166-174
11427701-4	2001	In females, muscimol treatment primarily decreased the phosphorylation of cAMP response element binding protein (CREB) within the hypothalamus and the CA1 region of the hippocampus.	Muscimol	12-20	cAMP responsive element binding protein 1	Rattus norvegicus	113-117
11427701-5	2001	In contrast, muscimol increased the phosphorylation of CREB in males within these same brain regions.	Muscimol	13-21	cAMP responsive element binding protein 1	Rattus norvegicus	55-59
11427701-6	2001	Within the arcuate nucleus, muscimol treatment increased the phosphorylation of CREB in both females and males.	Muscimol	28-36	cAMP responsive element binding protein 1	Rattus norvegicus	80-84
11509196-11	2001	We also found that infusions of the acetylcholinesterase inhibitor physostigmine (10 microg/microl) into the dorsal hippocampus, like intraseptal muscimol (20 ng/0.4 microl), increased open-arm exploration in the plus-maze test, and decreased burying behavior in the shock-probe test.	Muscimol	146-154	acetylcholinesterase	Rattus norvegicus	36-56
11294744-5	2001	Injection of muscimol into the DMH suppressed Fos expression in the PVN associated with air stress but not with hemorrhage.	Muscimol	13-21	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	46-49
11769310-6	2001	The hippocampal mossy fiber-CA3 synapses of PIMT-deficient mice showed hyperexcitation that was repressed by a gamma-aminobutyric acid (GABA)A receptor agonist muscimol.	Muscimol	160-168	carbonic anhydrase 3	Mus musculus	28-31
11160448-9	2001	Finally, all effects of GABA and muscimol at low concentrations were blocked by (1,2,5,6-tetrahydropyridine-4-yl) methylphosphinic acid, a specific GABA(C) receptor antagonist, but not by the specific GABA(A) receptor antagonist bicuculline.	Muscimol	33-41	gamma-aminobutyric acid type A receptor subunit rho3	Rattus norvegicus	148-164
11294744-0	2001	Injection of muscimol in dorsomedial hypothalamus and stress-induced Fos expression in paraventricular nucleus.	Muscimol	13-21	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	69-72
11222088-4	2001	While bath application of muscimol, DZP, or baclofen suppressed spontaneous activity in CA1 neurons not previously exposed to TMPP, subsequent application of TMPP (10 microM) reversed the actions of muscimol and diazepam, but not baclofen.	Muscimol	26-34	carbonic anhydrase 1	Rattus norvegicus	88-91
11346310-6	2001	The gamma(2)-MSH analgesic effect was moreover additive to the analgesia afforded by muscimol and ethanol, but not to that afforded by diazepam.	Muscimol	85-93	msh homeobox 1	Mus musculus	13-16
11544795-3	2001	Besides, Cd2+ decreased the currents evoked by muscimol application onto the neurons, which is evidence of an additional postsynaptic effect.	Muscimol	47-55	Cd2 molecule	Rattus norvegicus	9-12
11769310-6	2001	The hippocampal mossy fiber-CA3 synapses of PIMT-deficient mice showed hyperexcitation that was repressed by a gamma-aminobutyric acid (GABA)A receptor agonist muscimol.	Muscimol	160-168	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1	Mus musculus	44-48
11226707-5	2001	The EC(so) values for GABA and its analogues isoguvacine, muscimol, isonipecotic acid and 3-amino sulphonic acid on the RDL(ad) homomeric receptor differed from those previously described for RDL(ac) and DRC17-1-2 receptors.	Muscimol	58-66	Resistant to dieldrin	Drosophila melanogaster	120-123
11311534-4	2001	Embryos were exposed to the GABA(A) antagonist (bicuculline) or agonist (muscimol) during previously defined proliferative or post-proliferative periods for parvalbumin-immunoreactive interneurons.	Muscimol	73-81	parvalbumin	Rattus norvegicus	157-168
11152384-11	2000	In vitro, 0.1-1 mM concentrations of BAL inhibited [3H]glutamate and [3H]MK-801 binding, but increased the binding of [3H]muscimol to brain synaptic plasma membrane.	Muscimol	122-130	poly (ADP-ribose) polymerase family, member 9	Mus musculus	37-40
11190082-4	2000	A prolongation of extinction was observed in aggressive mice in comparison with control and submissive animals, and activation of GABAA by muscimol and benzodiazepine receptors by medazepam led to acceleration of extinction.	Muscimol	139-147	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	130-135
11080264-8	2000	In rats treated with anti-DH-SAP, inhibition of RVLM neurones by bilateral microinjection of muscimol eliminated splanchnic SNA and produced the same degree of hypotension as in control rats.	Muscimol	93-101	amyloid P component, serum	Rattus norvegicus	29-32
10773216-4	2000	The induction of LTP was completely blocked if the tetanus was delivered in the presence of muscimol (2.5 microM), a gamma-aminobutyric acid (GABA) receptor agonist.	Muscimol	92-100	GABA type A receptor-associated protein	Homo sapiens	117-156
10995817-7	2000	Immunocytochemical labeling of the receptors showed that the disappearance of receptor clusters in the somatic membrane as induced by muscimol stimulation was enhanced by Rac1 inactivation.	Muscimol	134-142	Rac family small GTPase 1	Rattus norvegicus	171-175
10959535-5	2000	Only the SFO- and LH-lesioned groups showed a suppression of drinking to systemic injections of angiotensin II, suggesting that the drinking elicited by intra-MR injections of muscimol may involve changes in the central circuits mediating angiotensin-induced drinking.	Muscimol	176-184	angiotensinogen	Rattus norvegicus	96-110
10718911-9	2000	When cells were pretreated with muscimol this increased the spike phase of the [Ca2+]i response to subsequent stimulation with gonadotropin-releasing hormone (GnRH).	Muscimol	32-40	gonadotropin releasing hormone 1	Homo sapiens	127-157
10762370-6	2000	Bilateral injections of muscimol (0.1, 1, 10 microg/microL per side), a GABAA (gamma-aminobutyric acid) agonist, into the anterior thalamus blocked HSP70 induction in the retrosplenial cortex produced by systemic dizocilpine (1 mg/kg).	Muscimol	24-32	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	148-153
10718911-9	2000	When cells were pretreated with muscimol this increased the spike phase of the [Ca2+]i response to subsequent stimulation with gonadotropin-releasing hormone (GnRH).	Muscimol	32-40	gonadotropin releasing hormone 1	Homo sapiens	159-163
10718911-10	2000	Similar amplification was seen in muscimol-pretreated cells stimulated with GnRH in Ca2+-free medium, but not when cells were pretreated with muscimol in Ca2+-free medium.	Muscimol	34-42	gonadotropin releasing hormone 1	Homo sapiens	76-80
10709211-2	2000	Infusion of GABA or of the GABA receptor agonist muscimol is considered one interesting reversible inactivation method because it may not affect fibers of passage and may therefore be compared to axon-sparing types of lesions.	Muscimol	49-57	GABA type A receptor-associated protein	Homo sapiens	27-40
10673071-4	2000	METHODS: Increasing concentrations of muscimol (0.05-50 microM), a specific GABA(A) receptor agonist, were added to HepG2 human hepatocellular carcinoma cells and alpha-fetoprotein (AFP) and albumin mRNA expression were determined for varying periods of time (maximum 24 h) thereafter.	Muscimol	38-46	alpha fetoprotein	Homo sapiens	163-180
10673071-4	2000	METHODS: Increasing concentrations of muscimol (0.05-50 microM), a specific GABA(A) receptor agonist, were added to HepG2 human hepatocellular carcinoma cells and alpha-fetoprotein (AFP) and albumin mRNA expression were determined for varying periods of time (maximum 24 h) thereafter.	Muscimol	38-46	alpha fetoprotein	Homo sapiens	182-185
10673071-6	2000	RESULTS: Muscimol significantly (p<0.0001) decreased AFP mRNA expression (maximum decrease: 65% below baseline values) without affecting albumin mRNA expression.	Muscimol	9-17	alpha fetoprotein	Homo sapiens	56-59
10673071-9	2000	In this series of experiments, in addition to AFP mRNA inhibition being as extensive and more prolonged (maximum duration: 6-12 h) in muscimol-treated, GABA(A) receptor-transfected cells, proliferative activity was also significantly inhibited when compared to saline-treated GABA(A) receptor-transfected controls (p<0.01) and muscimol-treated cells transfected with vector alone (p<0.005).	Muscimol	134-142	alpha fetoprotein	Homo sapiens	46-49
10828527-6	2000	Muscimol injection to the supramammillary nucleus prevented Fos expression in the CA1-CA3 region and reduced that in the forebrain regions with the latest Fos expression, but did not affect Fos expression in other forebrain regions with early Fos expression.	Muscimol	0-8	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	60-63
10854764-1	2000	We examined the effects of systemic administration of a GABA(A) receptor agonist, muscimol, or antagonist, bicuculline, on the expression of c-Fos protein induced 3h after electrical stimulation of the trigeminal ganglion at low (0.1 mA) or high intensities (1.	Muscimol	82-90	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	141-146
10854764-7	2000	muscimol and stimulated at 0.1 mA, the numbers of Fos-positive neurons in trigeminal nucleus caudalis, dorsomedial nucleus of trigeminal nucleus interpolaris, and dorsomedial nucleus of trigeminal nucleus oralis were significantly decreased.	Muscimol	0-8	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	50-53
10828527-6	2000	Muscimol injection to the supramammillary nucleus prevented Fos expression in the CA1-CA3 region and reduced that in the forebrain regions with the latest Fos expression, but did not affect Fos expression in other forebrain regions with early Fos expression.	Muscimol	0-8	carbonic anhydrase 1	Rattus norvegicus	82-85
10828527-6	2000	Muscimol injection to the supramammillary nucleus prevented Fos expression in the CA1-CA3 region and reduced that in the forebrain regions with the latest Fos expression, but did not affect Fos expression in other forebrain regions with early Fos expression.	Muscimol	0-8	carbonic anhydrase 3	Rattus norvegicus	86-89
10828527-6	2000	Muscimol injection to the supramammillary nucleus prevented Fos expression in the CA1-CA3 region and reduced that in the forebrain regions with the latest Fos expression, but did not affect Fos expression in other forebrain regions with early Fos expression.	Muscimol	0-8	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	155-158
10828527-6	2000	Muscimol injection to the supramammillary nucleus prevented Fos expression in the CA1-CA3 region and reduced that in the forebrain regions with the latest Fos expression, but did not affect Fos expression in other forebrain regions with early Fos expression.	Muscimol	0-8	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	155-158
10828527-6	2000	Muscimol injection to the supramammillary nucleus prevented Fos expression in the CA1-CA3 region and reduced that in the forebrain regions with the latest Fos expression, but did not affect Fos expression in other forebrain regions with early Fos expression.	Muscimol	0-8	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	155-158
10550002-8	1999	Sensitivity to muscimol (measured by percent increase in GH above basal levels) occurred at all ages and generally was greater in male compared to female tissue.	Muscimol	15-23	gonadotropin releasing hormone receptor	Rattus norvegicus	57-59
10670433-0	2000	The medial prefrontal cortex plays an important role in the excitation of A10 dopaminergic neurons following intravenous muscimol administration.	Muscimol	121-129	immunoglobulin kappa variable 6D-21 (non-functional)	Homo sapiens	74-77
10670433-1	2000	Intravenous muscimol administration increases the activity of dopaminergic neurons of the A10 cell group, located in the ventral tegmental area.	Muscimol	12-20	immunoglobulin kappa variable 6D-21 (non-functional)	Homo sapiens	90-93
10670433-3	2000	We hypothesized that the activation of A10 cells by muscimol is likely to be at least partly caused by the action of excitatory afferents.	Muscimol	52-60	immunoglobulin kappa variable 6D-21 (non-functional)	Homo sapiens	39-42
10670433-6	2000	The pedunculopontine tegmental nucleus itself appeared to make little intrinsic contribution to muscimol-induced excitation, although the results suggested that part of the excitation which originates in the forebrain may be conducted to A10 cells via the pedunculopontine tegmental nucleus.	Muscimol	96-104	immunoglobulin kappa variable 6D-21 (non-functional)	Homo sapiens	238-241
10670433-10	2000	The results suggest that under normal circumstances, an active excitation counteracts and exceeds the direct inhibitory effects of muscimol on the activity of A10 dopaminergic neurons.	Muscimol	131-139	immunoglobulin kappa variable 6D-21 (non-functional)	Homo sapiens	159-162
10594084-3	1999	Injections of the GABA(A) agonist muscimol into the AcbSh greatly increased the number of cells exhibiting Fos-like immunoreactivity in the LH, as well as in the lateral septum, paraventricular hypothalamic nucleus, ventral tegmental area, substantia nigra pars compacta, and nucleus of the solitary tract.	Muscimol	34-42	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	107-110
10550002-9	1999	Furthermore, the efficacy of bicuculline in depressing muscimol-induced GH secretion increased with age in both sexes.	Muscimol	55-63	gonadotropin releasing hormone receptor	Rattus norvegicus	72-74
10550002-14	1999	More apparent was the reduced capacity of bicuculline to reverse muscimol-induced GH release from male tissue.	Muscimol	65-73	gonadotropin releasing hormone receptor	Rattus norvegicus	82-84
10554880-9	1999	Administration of the GABA(A) receptor agonist, muscimol, but not the GABA(A) receptor antagonists bicuculline and picrotoxin, decreased the naloxone response in morphine-dependent animals.	Muscimol	48-56	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	22-29
10581643-15	1999	The results suggest that there is an interaction between muscimol-induced long-term depression and brain-derived neurotrophic factor and may explain the post receptor mechanism of muscimol-induced long-term depression through a bilateral relation between GABAA activity and brain-derived neurotrophic factor.	Muscimol	180-188	brain-derived neurotrophic factor	Rattus norvegicus	274-307
10515994-6	1999	Muscimol, a potent GABA(A) and GABA(C) receptor agonist, strongly attenuated this postsynaptic potential at concentrations >10 microM.	Muscimol	0-8	gamma-aminobutyric acid type A receptor subunit rho3	Rattus norvegicus	31-47
10581643-0	1999	Prevention of muscimol-induced long-term depression by brain-derived neurotrophic factor.	Muscimol	14-22	brain-derived neurotrophic factor	Rattus norvegicus	55-88
10581643-8	1999	The present study investigated a possible relation between muscimol-induced long-term depression and brain-derived neurotrophic factor level.	Muscimol	59-67	brain-derived neurotrophic factor	Rattus norvegicus	101-134
10581643-12	1999	It was observed that brain-derived neurotrophic factor at concentration that did not have any effect itself on the population spike, prevents the induction of long-term depression by muscimol.	Muscimol	183-191	brain-derived neurotrophic factor	Rattus norvegicus	21-54
10581643-13	1999	In addition to this, K-252a an inhibitor of Trk type kinase blocked the prevention of muscimol-induced LTD by brain-derived neurotrophic factor.	Muscimol	86-94	neurotrophic receptor tyrosine kinase 1	Rattus norvegicus	44-47
10581643-13	1999	In addition to this, K-252a an inhibitor of Trk type kinase blocked the prevention of muscimol-induced LTD by brain-derived neurotrophic factor.	Muscimol	86-94	brain-derived neurotrophic factor	Rattus norvegicus	110-143
10581643-15	1999	The results suggest that there is an interaction between muscimol-induced long-term depression and brain-derived neurotrophic factor and may explain the post receptor mechanism of muscimol-induced long-term depression through a bilateral relation between GABAA activity and brain-derived neurotrophic factor.	Muscimol	57-65	brain-derived neurotrophic factor	Rattus norvegicus	99-132
10581643-15	1999	The results suggest that there is an interaction between muscimol-induced long-term depression and brain-derived neurotrophic factor and may explain the post receptor mechanism of muscimol-induced long-term depression through a bilateral relation between GABAA activity and brain-derived neurotrophic factor.	Muscimol	57-65	brain-derived neurotrophic factor	Rattus norvegicus	274-307
10581643-15	1999	The results suggest that there is an interaction between muscimol-induced long-term depression and brain-derived neurotrophic factor and may explain the post receptor mechanism of muscimol-induced long-term depression through a bilateral relation between GABAA activity and brain-derived neurotrophic factor.	Muscimol	180-188	brain-derived neurotrophic factor	Rattus norvegicus	99-132
10421877-5	1999	Microinjection of either a GABA(A) agonist, muscimol, or a GABA(B) agonist, baclofen, into the SCN region significantly reduced light-induced c-Fos-ir within the SCN when administered before light exposure at circadian time (CT) 13.5 or CT 19.	Muscimol	44-52	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	142-147
10421877-5	1999	Microinjection of either a GABA(A) agonist, muscimol, or a GABA(B) agonist, baclofen, into the SCN region significantly reduced light-induced c-Fos-ir within the SCN when administered before light exposure at circadian time (CT) 13.5 or CT 19.	Muscimol	44-52	interleukin 13 receptor subunit alpha 2	Homo sapiens	237-242
9758160-5	1998	Evaluation for functional significance of the down-regulated gamma2 and alpha5 subunit was made by determining the GABAA receptor function assessed by measurement of muscimol-stimulated 36Cl- uptake in cerebral cortical membrane vesicles.	Muscimol	166-174	crystallin, gamma E	Rattus norvegicus	61-78
10077361-3	1999	The following results were obtained: muscimol inhibited LHRH secretion, and this effect was accompanied by a decrease of NE, E and DA output.	Muscimol	37-45	gonadotropin releasing hormone 1	Rattus norvegicus	56-60
9765333-5	1998	In the restraint-stressed animals, muscimol and baclofen inhibited the stress-induced plasma IL-6 levels from the dose of 50 and 15 ng, respectively.	Muscimol	35-43	interleukin 6	Mus musculus	93-97
9832927-4	1998	STM was unaffected by any of the treatments given into PRE, and was inhibited by CNQX or muscimol given into CA1, PP and EC and by scopolamine given into PP, and enhanced by SCH given into CA1.	Muscimol	89-97	carbonic anhydrase 1	Rattus norvegicus	109-112
10391897-1	1999	Using a novel antibody directed against the alpha4 subunit of gamma-aminobutyric acidA (GABAA) receptors, 5% of all [3H]muscimol but only about 2% of all [3H]Ro15-4513 binding sites present in brain membrane extracts could be precipitated.	Muscimol	120-128	immunoglobulin binding protein 1	Homo sapiens	44-50
10391897-2	1999	This indicated that part of the alpha4 receptors containing [3H]muscimol binding sites did not contain [3H]Ro15-4513 binding sites.	Muscimol	64-72	immunoglobulin binding protein 1	Homo sapiens	32-38
10095042-0	1999	Concentration-dependent effects of muscimol to enhance pulsatile GnRH release from GT1-7 neurons in vitro.	Muscimol	35-43	gonadotropin releasing hormone 1	Homo sapiens	65-69
10095042-0	1999	Concentration-dependent effects of muscimol to enhance pulsatile GnRH release from GT1-7 neurons in vitro.	Muscimol	35-43	beta-1,4-galactosyltransferase 1	Homo sapiens	83-88
10095042-1	1999	Immortalized GT1-7 neurons were used to characterize the effect of muscimol, a GABAA receptor agonist, to enhance pulsatile gonadotropin-releasing hormone (GnRH) release.	Muscimol	67-75	gonadotropin releasing hormone 1	Homo sapiens	124-154
10095042-1	1999	Immortalized GT1-7 neurons were used to characterize the effect of muscimol, a GABAA receptor agonist, to enhance pulsatile gonadotropin-releasing hormone (GnRH) release.	Muscimol	67-75	gonadotropin releasing hormone 1	Homo sapiens	156-160
10095042-8	1999	Our results also demonstrated that the GABAA receptor agonist, muscimol, enhances pulsatile GnRH release from GT1-7 neurons in culture.	Muscimol	63-71	gonadotropin releasing hormone 1	Homo sapiens	92-96
10095042-8	1999	Our results also demonstrated that the GABAA receptor agonist, muscimol, enhances pulsatile GnRH release from GT1-7 neurons in culture.	Muscimol	63-71	beta-1,4-galactosyltransferase 1	Homo sapiens	110-115
10095042-10	1999	The effects of 5 microM muscimol to increase GnRH pulsatility were blocked by co-exposure to the GABAA receptor antagonist, bicuculline.	Muscimol	24-32	gonadotropin releasing hormone 1	Homo sapiens	45-49
10095042-12	1999	GnRH pulse amplitude (mean-area for each pulse) was increased during exposure to muscimol but not during the pre- or post-muscimol periods.	Muscimol	81-89	gonadotropin releasing hormone 1	Homo sapiens	0-4
10200227-1	1999	A small amount of muscimol (1 microl; concentration, 5 microg/microl) was injected into the ventral and dorsal premotor cortex areas (PMv and PMd, respectively) of monkeys, which then were required to perform a visually guided reaching task.	Muscimol	18-26	Mitral valve prolapse, familial	Homo sapiens	134-137
10200227-7	1999	After muscimol injection into the PMv, the monkeys lost the ability to readapt and touched the screen closer to the location of the targets as seen through the prisms.	Muscimol	6-14	Mitral valve prolapse, familial	Homo sapiens	34-37
9927326-6	1999	Therefore, the effects of muscimol (MUS), a GABA(A) receptor agonist, on NPY-induced food intake were examined in sated rats.	Muscimol	26-34	neuropeptide Y	Rattus norvegicus	73-76
9927326-6	1999	Therefore, the effects of muscimol (MUS), a GABA(A) receptor agonist, on NPY-induced food intake were examined in sated rats.	Muscimol	36-39	neuropeptide Y	Rattus norvegicus	73-76
10636469-1	1999	In the hypothalamic paraventricular nucleus (PVN), the proenkephalin gene may be upregulated by lipopolysaccharide (LPS) and downregulated by the GABA-A agonist muscimol.	Muscimol	161-169	proenkephalin	Homo sapiens	55-68
10636469-5	1999	PhosphoCREB is downregulated and CREM/ICER is upregulated in the PVN by muscimol, suggesting that the regulation of these transcription factors may underlie the inhibitory effect of muscimol on target genes in the PVN.	Muscimol	72-80	cAMP responsive element modulator	Homo sapiens	33-37
10636469-5	1999	PhosphoCREB is downregulated and CREM/ICER is upregulated in the PVN by muscimol, suggesting that the regulation of these transcription factors may underlie the inhibitory effect of muscimol on target genes in the PVN.	Muscimol	72-80	cAMP responsive element modulator	Homo sapiens	38-42
10636469-5	1999	PhosphoCREB is downregulated and CREM/ICER is upregulated in the PVN by muscimol, suggesting that the regulation of these transcription factors may underlie the inhibitory effect of muscimol on target genes in the PVN.	Muscimol	182-190	cAMP responsive element modulator	Homo sapiens	33-37
10636469-5	1999	PhosphoCREB is downregulated and CREM/ICER is upregulated in the PVN by muscimol, suggesting that the regulation of these transcription factors may underlie the inhibitory effect of muscimol on target genes in the PVN.	Muscimol	182-190	cAMP responsive element modulator	Homo sapiens	38-42
9622252-4	1998	injection of the GABA(A) receptor agonist muscimol (4 mg/kg) potentiated the corticotropin-releasing hormone messenger RNA decrease ( - 34%).	Muscimol	42-50	corticotropin releasing hormone	Rattus norvegicus	77-108
9595284-9	1998	Administration of the GABAA receptor agonist muscimol but not the GABAB receptor agonist baclofen decreased the acquisition of the learned task.	Muscimol	45-53	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	22-27
9595284-18	1998	The GABAA antagonists reduced the inhibitory effect of muscimol, whereas a higher dose of phaclofen increased the inhibition of the physostigmine response induced by muscimol and baclofen on physostigmine-induced learning improvement.	Muscimol	55-63	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	4-9
9713333-9	1998	To substantiate the involvement of the GABAA receptor further, we tested the effects of muscimol, a selective agonist for this receptor, which suppressed GnRH release.	Muscimol	88-96	gonadotropin releasing hormone 1	Homo sapiens	154-158
9660895-11	1998	In contrast to the effect on most neurons, GABA as well as muscimol led to a (reversible) depolarization of the membrane potential of STC-1 cells.	Muscimol	59-67	stanniocalcin 1	Mus musculus	134-139
9660895-14	1998	In accordance with the observed membrane depolarization and activation of voltage-gated Ca2+ channels, both GABA and muscimol stimulated Ca2+-dependent CCK release.	Muscimol	117-125	cholecystokinin	Mus musculus	152-155
9607779-9	1998	In contrast, LHRH mRNA levels decreased in explants cultured with the GABA(A) receptor agonist, muscimol (10(-4) M), or KCl (50 mM).	Muscimol	96-104	gonadotropin releasing hormone 1	Mus musculus	13-17
9776382-5	1998	Pharmacologically, GABA, muscimol and ZAPA ((Z)-3[(aminiiminomethyl)thio]prop-2-enoic acid sulphate) produced responses with ligand-specific kinetics, whereas glycine and the GABA(C) receptor agonist CACA were without effect; bicuculline methochloride acted as a competitive antagonist.	Muscimol	25-33	gamma-aminobutyric acid type A receptor subunit rho 2	Rattus norvegicus	175-191
9603245-12	1998	Phosphorylated CREB was not observed in control or P4-treated cultures, but it was detected in the majority of both small and large GCs exposed to either 8-br-cAMP or muscimol.	Muscimol	167-175	cAMP responsive element binding protein 1	Rattus norvegicus	15-19
9603245-13	1998	Since activation of the GABA(A) receptor with muscimol increases phosphorylated CREB but P4 does not, this study indicates that P4 does not activate the ovarian GABA(A) receptor.	Muscimol	46-54	cAMP responsive element binding protein 1	Rattus norvegicus	80-84
9490842-16	1998	Synaptic stimulation and application of the GABAA receptor agonist muscimol mimicked the spontaneous Ca2+ transients in pyramidal neurones.	Muscimol	67-75	carbonic anhydrase 2	Rattus norvegicus	101-104
9590437-8	1998	The GABA(A) receptor agonist muscimol (50 microM) also protected the THIP-treated cultures against lindane-induced cytotoxicity.	Muscimol	29-37	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	4-11
9490842-17	1998	The efficacy of muscimol in evoking Ca2+ transients decreased during development in parallel with the gradual disappearance of the ENOs.	Muscimol	16-24	carbonic anhydrase 2	Rattus norvegicus	36-39
9367268-2	1997	Fos-like immunoreactivity induced by intra-NAC infusion of muscimol was seen ipsilaterally in many accumbofugal target areas, but no Fos-positive neurons were seen in the vicinity of the dialysis membrane in the NAC.	Muscimol	59-67	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	0-3
9526063-4	1998	In addition, the exposure of the neurons for 3 days significantly elevated the expression of DBI mRNA, which was completely inhibited by concomitant exposure of FLN, Ro15-4513 and Ro-15-1788 with EtOH, while muscimol and bicuculline showed no effects on the EtOH-induced increase of DBI mRNA expression.	Muscimol	208-216	diazepam binding inhibitor	Mus musculus	93-96
9779197-9	1998	When hypoxia was combined with CHI, significant increase in [3H] GLU binding to NMDA receptors and significant decrease in [3H]-muscimol binding to GABAA receptors were observed in CA1 and CA3 at 1 h and 24 h post-insult.	Muscimol	128-136	carbonic anhydrase 1	Rattus norvegicus	181-184
9779197-9	1998	When hypoxia was combined with CHI, significant increase in [3H] GLU binding to NMDA receptors and significant decrease in [3H]-muscimol binding to GABAA receptors were observed in CA1 and CA3 at 1 h and 24 h post-insult.	Muscimol	128-136	carbonic anhydrase 3	Rattus norvegicus	189-192
9465270-5	1998	On the other hand, the benzodiazepine agonist diazepam (DZ), the GABAA agonist muscimol (MUS) and the GABAB agonist baclofen (BAC) all attenuated the effect of TRCP.	Muscimol	79-87	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	65-70
9330360-7	1997	c-Fos immunohistochemistry was used routinely to provide regional estimates of the suppressive effects of muscimol on neuronal activity.	Muscimol	106-114	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	0-5
9367268-0	1997	Local muscimol disinhibits mesolimbic dopaminergic activity as examined by brain microdialysis and Fos immunohistochemistry.	Muscimol	6-14	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	99-102
9409710-9	1997	Muscimol (100 microM) produced either depolarizing or hyperpolarizing effects on Vm with an input resistance decrease in CA1-PCs, and it depolarized Vm with an input resistance decrease in DG-GCs.	Muscimol	0-8	carbonic anhydrase 1	Rattus norvegicus	121-124
9063694-4	1997	The selective GABAA receptor agonist, muscimol, also arrested [Ca2+]i pulsing after causing a transient rise in [Ca2+]i.	Muscimol	38-46	GABA(A) receptor-associated protein L homeolog	Xenopus laevis	14-19
9226420-3	1997	The potency of muscimol and GABA to inhibit the binding of the GABA(A) receptor antagonist [3H]SR 95531 (2-(3-carboxypropyl)-3-amino-6-(4-methoxyphenyl)pyridazinium bromide) was higher in receptor complexes of alpha1(ile 121) beta2gamma2 than in those of alpha1(val 121) beta2gamma2 (IC50 values were 32-fold and 26-fold lower for muscimol and GABA, respectively).	Muscimol	15-23	adrenoceptor alpha 1D	Homo sapiens	210-224
9226420-3	1997	The potency of muscimol and GABA to inhibit the binding of the GABA(A) receptor antagonist [3H]SR 95531 (2-(3-carboxypropyl)-3-amino-6-(4-methoxyphenyl)pyridazinium bromide) was higher in receptor complexes of alpha1(ile 121) beta2gamma2 than in those of alpha1(val 121) beta2gamma2 (IC50 values were 32-fold and 26-fold lower for muscimol and GABA, respectively).	Muscimol	15-23	adrenoceptor alpha 1D	Homo sapiens	255-269
9166743-3	1997	We have shown previously that muscimol-evoked 36Cl- efflux and paired-pulse inhibition (involving GABA(A)-mediated recurrent inhibition) were decreased persistently in the CA1 region of hippocampal slices from chronic intermittent ethanol (CIE)-treated rats.	Muscimol	30-38	carbonic anhydrase 1	Rattus norvegicus	172-175
9087523-1	1997	Labeling of the two more important gamma-aminobutyric acidA (GABA(A)) supramolecular sites with [3H] muscimol (GABA(A)) and [3H] flunitrazepam (benzodiazepine) provided saturable, stable, and dimorphic binding activities in cortical and limbic regions of the wood mouse Apodemus sylvaticus.	Muscimol	101-109	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	35-68
9087523-1	1997	Labeling of the two more important gamma-aminobutyric acidA (GABA(A)) supramolecular sites with [3H] muscimol (GABA(A)) and [3H] flunitrazepam (benzodiazepine) provided saturable, stable, and dimorphic binding activities in cortical and limbic regions of the wood mouse Apodemus sylvaticus.	Muscimol	101-109	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	61-68
9089469-4	1997	When GnRH secretion is evoked by muscimol and NMDA, a time-related reduction of GnRH secretion is caused by antisense oligodeoxynucleotides for the beta subunit of the GABAA receptor and the NR2A subunit of the NMDA receptor, respectively.	Muscimol	33-41	gonadotropin releasing hormone 1	Rattus norvegicus	5-9
9089469-4	1997	When GnRH secretion is evoked by muscimol and NMDA, a time-related reduction of GnRH secretion is caused by antisense oligodeoxynucleotides for the beta subunit of the GABAA receptor and the NR2A subunit of the NMDA receptor, respectively.	Muscimol	33-41	gonadotropin releasing hormone 1	Rattus norvegicus	80-84
9089469-4	1997	When GnRH secretion is evoked by muscimol and NMDA, a time-related reduction of GnRH secretion is caused by antisense oligodeoxynucleotides for the beta subunit of the GABAA receptor and the NR2A subunit of the NMDA receptor, respectively.	Muscimol	33-41	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	191-195
9089469-7	1997	Using several missense oligodeoxynucleotides or antisense for the NR2B and NR2C subunits of the NMDA receptor, the muscimol- and NMDA-evoked release of GnRH is not affected.	Muscimol	115-123	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	66-70
9089469-7	1997	Using several missense oligodeoxynucleotides or antisense for the NR2B and NR2C subunits of the NMDA receptor, the muscimol- and NMDA-evoked release of GnRH is not affected.	Muscimol	115-123	glutamate ionotropic receptor NMDA type subunit 2C	Rattus norvegicus	75-79
9089469-7	1997	Using several missense oligodeoxynucleotides or antisense for the NR2B and NR2C subunits of the NMDA receptor, the muscimol- and NMDA-evoked release of GnRH is not affected.	Muscimol	115-123	gonadotropin releasing hormone 1	Rattus norvegicus	152-156
9089470-5	1997	At the three studied ages, the muscimol-evoked release of GnRh is similarly inhibited by the GABAA receptor antagonist bicuculline.	Muscimol	31-39	gonadotropin releasing hormone 1	Rattus norvegicus	58-62
9089470-12	1997	At 25 days, muscimol can prevent the developmental increase in frequency of pulsatile GnRH secretion.	Muscimol	12-20	gonadotropin releasing hormone 1	Rattus norvegicus	86-90
8785053-4	1996	The GABA(A) receptor agonist muscimol and BDNF increased the size and neuropeptide Y (NPY) immunoreactivity of hippocampal interneurons.	Muscimol	29-37	neuropeptide Y	Homo sapiens	70-84
9058049-5	1997	We also found that activation of the GABAA receptor by GABA or muscimol inhibited the proliferative effects of bFGF on cortical progenitors, leading to an increased number of differentiated neurons.	Muscimol	63-71	fibroblast growth factor 2	Homo sapiens	111-115
9042566-0	1997	Prevention of kainic acid-induced limbic seizures and Fos expression by the GABA-A receptor agonist muscimol.	Muscimol	100-108	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	54-57
9042566-5	1997	Following 0.5 mg/kg muscimol treatment a remarkable decrease of Fos expression occurred but only in the caudate putamen and core of the accumbens nucleus.	Muscimol	20-28	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	64-67
9042566-6	1997	Treatment with 1 mg/kg muscimol led to further significant decreases of Fos expression in CA1-3 pyramidal neurons and the disappearance of Fos induction in the cerebral cortex above the rhinal fissure, reticular thalamic nucleus, claustrum, fundus striati, ventral pallidum, septal nucleus, lateral habenular nucleus, and lateral amygdaloid nucleus.	Muscimol	23-31	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	72-75
9042566-6	1997	Treatment with 1 mg/kg muscimol led to further significant decreases of Fos expression in CA1-3 pyramidal neurons and the disappearance of Fos induction in the cerebral cortex above the rhinal fissure, reticular thalamic nucleus, claustrum, fundus striati, ventral pallidum, septal nucleus, lateral habenular nucleus, and lateral amygdaloid nucleus.	Muscimol	23-31	carbonic anhydrase 1	Rattus norvegicus	90-93
9042566-6	1997	Treatment with 1 mg/kg muscimol led to further significant decreases of Fos expression in CA1-3 pyramidal neurons and the disappearance of Fos induction in the cerebral cortex above the rhinal fissure, reticular thalamic nucleus, claustrum, fundus striati, ventral pallidum, septal nucleus, lateral habenular nucleus, and lateral amygdaloid nucleus.	Muscimol	23-31	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	139-142
9042566-7	1997	When 2 mg/kg muscimol was injected, animals exhibited "absence seizures" instead of limbic seizures, and Fos expression in the hippocampus was effectively blocked.	Muscimol	13-21	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	105-108
9443367-1	1997	The supplementary motor area (SMA) was reversibly inactivated by muscimol microinfusion in two monkeys while they were performing two motor tasks: (1) a delayed conditional bimanual drawer pulling and grasping sequence which was initiated on a self-paced basis; (2) a unimanual reach and grasp task (modified Kluver board task).	Muscimol	65-73	survival of motor neuron 1, telomeric	Homo sapiens	30-33
9239690-5	1996	Muscimol, a GABAA receptor agonist, increased VCL, the percentage of active spermatozoa, and hyperactivation by about the same extent as GABA, suggesting the involvement of the GABAA receptor.	Muscimol	0-8	vinculin	Homo sapiens	46-49
8805122-0	1996	Fos oncoprotein expression in the rat forebrain following muscimol-induced absence seizures.	Muscimol	58-66	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	0-3
8805122-3	1996	Six hours after a systemic injection of muscimol a massive Fos immunoreactivity appeared in the olfactory system, retrosplenial cortex and paraventricular thalamic nucleus, whereas other cortical areas contained low level of Fos expression.	Muscimol	40-48	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	59-62
8805122-3	1996	Six hours after a systemic injection of muscimol a massive Fos immunoreactivity appeared in the olfactory system, retrosplenial cortex and paraventricular thalamic nucleus, whereas other cortical areas contained low level of Fos expression.	Muscimol	40-48	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	225-228
8805122-4	1996	These results provide the first functional morphological evidence suggesting that these forebrain structures with Fos expression may play an important role in the pathophysiology of muscimol-induced absence seizures.	Muscimol	182-190	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	114-117
8818409-2	1996	We report there the effects of two steroids (alfaxalone and pregnenolone sulfate) on the inhibition induced by two GABAA agonists, 3-amino propane sulphonic acid (3-APS) and muscimol, on the extracellular evoked potentials obtained in CA1 of mice hippocampi.	Muscimol	174-182	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	115-120
8818409-2	1996	We report there the effects of two steroids (alfaxalone and pregnenolone sulfate) on the inhibition induced by two GABAA agonists, 3-amino propane sulphonic acid (3-APS) and muscimol, on the extracellular evoked potentials obtained in CA1 of mice hippocampi.	Muscimol	174-182	carbonic anhydrase 1	Mus musculus	235-238
8814891-0	1996	Fos-like immunoreactivity in the mamillary body and thalamus following injections of muscimol into the ventral tegmental nucleus of Gudden in the rat.	Muscimol	85-93	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	0-3
8814891-2	1996	The current study examined Fos-like immunoreactivity in the mamillary body and the anterior thalamus following unilateral injections of the inhibitory GABA-A agonist muscimol into the ventral tegmental nucleus of Gudden (VTN).	Muscimol	166-174	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	27-30
8814891-2	1996	The current study examined Fos-like immunoreactivity in the mamillary body and the anterior thalamus following unilateral injections of the inhibitory GABA-A agonist muscimol into the ventral tegmental nucleus of Gudden (VTN).	Muscimol	166-174	vitronectin	Rattus norvegicus	221-224
8785053-4	1996	The GABA(A) receptor agonist muscimol and BDNF increased the size and neuropeptide Y (NPY) immunoreactivity of hippocampal interneurons.	Muscimol	29-37	neuropeptide Y	Homo sapiens	86-89
8785053-6	1996	At later developmental stages, when GABA represses BDNF synthesis, treatment with muscimol induced a decrease in cell size and NPY immunoreactivity of interneurons.	Muscimol	82-90	brain derived neurotrophic factor	Homo sapiens	51-55
8785053-6	1996	At later developmental stages, when GABA represses BDNF synthesis, treatment with muscimol induced a decrease in cell size and NPY immunoreactivity of interneurons.	Muscimol	82-90	neuropeptide Y	Homo sapiens	127-130
8612322-7	1995	Either type of NMDA antagonists (AP5 and MK801) and the GABAA agonist muscimol significantly reduced fos-LIR at all ages.	Muscimol	70-78	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	101-104
8612322-7	1995	Either type of NMDA antagonists (AP5 and MK801) and the GABAA agonist muscimol significantly reduced fos-LIR at all ages.	Muscimol	70-78	CD300c molecule	Homo sapiens	105-108
7671799-3	1995	Here we show, that GABA and the GABAA receptor agonist muscimol induce c-Fos immunoreactivity and increase BDNF mRNA expression in embryonic hippocampal neurons cultured for 5 days.	Muscimol	55-63	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	71-76
8590069-0	1995	Effect of muscimol on haloperidol-induced alteration of neurotensin gene expression in the striatum and nucleus accumbens in the rat.	Muscimol	10-18	neurotensin	Rattus norvegicus	56-67
8590069-2	1995	The purpose of this study was to examine modulation of neuroleptic induction of NT/N and the proto-oncogene c-fos expression by the GABAA agonist muscimol.	Muscimol	146-154	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	93-113
8590069-7	1995	However, co-administration of muscimol with haloperidol reduced haloperidol-induced increases in NT/N as well as c-fos mRNA in the dorsolateral striatum.	Muscimol	30-38	steroid sulfatase	Rattus norvegicus	110-114
8590069-7	1995	However, co-administration of muscimol with haloperidol reduced haloperidol-induced increases in NT/N as well as c-fos mRNA in the dorsolateral striatum.	Muscimol	30-38	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	115-118
7671799-7	1995	The differential regulation of c-fos and BDNF expression by GABA and muscimol in developing and mature hippocampal neurons is due to a switch in the ability of GABAA receptors to activate voltage-gated Ca2+ channels.	Muscimol	69-77	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	31-36
7671799-7	1995	The differential regulation of c-fos and BDNF expression by GABA and muscimol in developing and mature hippocampal neurons is due to a switch in the ability of GABAA receptors to activate voltage-gated Ca2+ channels.	Muscimol	69-77	brain-derived neurotrophic factor	Rattus norvegicus	41-45
8690249-2	1995	In morphine-dependent mice, muscimol, a GABAA agonist when given i.p.	Muscimol	28-36	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	40-45
8590044-4	1995	In hippocampal slices, muscimol (50 microM)-evoked 36Cl- efflux was higher in CA1 (112.5 +/- 27.9% above basal efflux rate) than in DG slices (29.7 +/- 5.6%).	Muscimol	23-31	carbonic anhydrase 1	Rattus norvegicus	78-81
8590044-5	1995	In the presence of ZnCl2, the muscimol effect on efflux rate in CA1 and DG regions was decreased to 10.6 +/- 5.4% and 6.9 +/- 4.9%, respectively.	Muscimol	30-38	carbonic anhydrase 1	Rattus norvegicus	64-67
7671799-3	1995	Here we show, that GABA and the GABAA receptor agonist muscimol induce c-Fos immunoreactivity and increase BDNF mRNA expression in embryonic hippocampal neurons cultured for 5 days.	Muscimol	55-63	brain-derived neurotrophic factor	Rattus norvegicus	107-111
7476025-4	1995	The tyrosine kinase inhibitors, genistein and the tyrphostins B-42 and B-44, inhibited muscimol-stimulated 36Cl- uptake in mouse brain membrane vesicles (microsacs).	Muscimol	87-95	proline-rich nuclear receptor coactivator 1	Mus musculus	62-75
7760041-1	1995	Muscimol-stimulated radiotracer 36CI- uptake in synaptoneurosomes was used to investigate the function of the GABAA receptor complex in the CA1-3 area and fascia dentata (granular and molecular layers and hilus) of rats kindled by stimulation, twice a day, of the Schaffer collateral fibers.	Muscimol	0-8	carbonic anhydrase 1	Rattus norvegicus	140-143
7750481-6	1995	Serum LH levels were significantly reduced by muscimol but not by baclofen within 2 h. The activation of GABA-A receptors with muscimol resulted in a significant inhibition in GnRHR transcript level in both the pMBH and POA but not in the pituitary.	Muscimol	46-54	gonadotropin releasing hormone receptor	Rattus norvegicus	176-181
7750481-6	1995	Serum LH levels were significantly reduced by muscimol but not by baclofen within 2 h. The activation of GABA-A receptors with muscimol resulted in a significant inhibition in GnRHR transcript level in both the pMBH and POA but not in the pituitary.	Muscimol	127-135	gonadotropin releasing hormone receptor	Rattus norvegicus	176-181
7760041-4	1995	In FK animals, the muscimol-stimulated 36CI- uptake was significantly reduced by 21% in the CA1-3 area in comparison with nonstimulated controls, whereas a significant increase of 29% was found in the fascia dentata.	Muscimol	19-27	carbonic anhydrase 1	Rattus norvegicus	92-97
7760041-6	1995	The observed changes in muscimol-stimulated 36CI- uptake at the FK stage closely parallel the recently observed changes in [3H]muscimol binding in the CA1 area and fascia dentata.	Muscimol	24-32	carbonic anhydrase 1	Rattus norvegicus	151-154
7760041-6	1995	The observed changes in muscimol-stimulated 36CI- uptake at the FK stage closely parallel the recently observed changes in [3H]muscimol binding in the CA1 area and fascia dentata.	Muscimol	127-135	carbonic anhydrase 1	Rattus norvegicus	151-154
7792718-4	1995	High doses of MK 801, CPP or muscimol infused into the SN produced intense contralateral turning per se and induced a sparse c-fos expression in the lesioned CPu which was antagonized by parenteral administration of MK 801.	Muscimol	29-37	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	125-130
7544879-2	1995	In vivo, this inhibitory action appears to be mediated via the GABAA receptor since in ovariectomized (ovx) rats and sheep direct application of muscimol (MUS), a GABAA agonist, into the preoptic area (POA), the site were the GnRH cell bodies are located, caused an immediate reduction of LH release.	Muscimol	145-153	Progonadoliberin-1	Ovis aries	226-230
7617125-11	1995	Activation of GABA-A receptor with muscimol at a low dose (5 nmol) but not at high doses (10 and 30 nmol) elevated GnRH mRNA levels by 60% over the control value.	Muscimol	35-43	gonadotropin releasing hormone 1	Rattus norvegicus	115-119
7621898-2	1995	The steroids 3 alpha-hydroxy-5 alpha-pregnan-20-one (3 alpha-OH-DHP), pregnenolone sulfate and 3 alpha-OH-DHP sulfate have different modulatory effects on [3H]muscimol or [3H]Ro15-4513 binding to the alpha 6 beta 2 gamma 2 than to the alpha 1 beta 2 gamma 2 receptor.	Muscimol	159-167	dihydropyrimidinase	Homo sapiens	64-67
7621898-2	1995	The steroids 3 alpha-hydroxy-5 alpha-pregnan-20-one (3 alpha-OH-DHP), pregnenolone sulfate and 3 alpha-OH-DHP sulfate have different modulatory effects on [3H]muscimol or [3H]Ro15-4513 binding to the alpha 6 beta 2 gamma 2 than to the alpha 1 beta 2 gamma 2 receptor.	Muscimol	159-167	dihydropyrimidinase	Homo sapiens	106-109
7675945-8	1995	In addition, it was found that OFD elicited by local injections of picrotoxin (250 ng) into the STH was significantly attenuated by SP injections of the broad spectrum glutamate antagonist kynurenic acid in a dose (1000 ng) which itself was ineffective, but not by muscimol (100 ng), indicating that the STH-elicited OFD needs an intact and functioning glutaminergic, but not GABAergic, transmission process in the SP for its expression.	Muscimol	265-273	saitohin	Homo sapiens	96-99
7731981-5	1995	[3H]Muscimol, but not [3H]flunitrazepam, bound with high affinity to GT1-1 cell membranes (Kd = 10.9 +/- 0.3 nM; Bmax = 979 +/- 12 fmol/mg of protein), and [3H]muscimol binding was enhanced by 3 alpha,5 alpha-THP.	Muscimol	4-12	retinoic acid induced 1	Mus musculus	69-74
7731981-8	1995	GnRH release studies showed a dose-related stimulating action of muscimol.	Muscimol	65-73	gonadotropin releasing hormone 1	Mus musculus	0-4
8713359-2	1995	In vitro receptor binding autoradiography was used to examine the pattern and intensity of [3H]muscimol binding to GABAA receptors.	Muscimol	95-103	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	115-120
7533909-2	1994	Stably-transfected clonal cell lines which expressed high levels of GABA receptor were identified by specific [3H]-muscimol binding.	Muscimol	115-123	Resistant to dieldrin	Drosophila melanogaster	68-81
7735289-1	1995	Injection of muscimol in the caudal ventrolateral medulla increases blood pressure and stimulates neuronal c-fos expression in the rostral ventral medulla (RVM).	Muscimol	13-21	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	107-112
7735289-2	1995	The blockade of c-fos expression in the RVM by antisense oligonucleotides attenuates the blood pressure response to this muscimol-induced disinhibition of the RVM and also reduces resting blood pressure.	Muscimol	121-129	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	16-21
7820637-1	1994	In rats, secretion of vasopressin initiated by hemorrhage was completely abolished after muscimol-induced inhibition of neuronal function in the A1 region of the ventrolateral medulla oblongata.	Muscimol	89-97	arginine vasopressin	Rattus norvegicus	22-33
7965056-6	1994	Homooligomeric rho 2 and rho 1 receptors are less sensitive to muscimol and picrotoxin, and desensitize slower than GABAA receptors.	Muscimol	63-71	gamma-aminobutyric acid type A receptor subunit rho2	Homo sapiens	15-20
7974555-9	1994	Treatment with intravenous muscimol at 5 mg/kg significantly prolonged the P50 (32.4 +/- 1.3; P = .01).	Muscimol	27-35	Y-box-binding protein 1	Oryctolagus cuniculus	75-78
7845588-3	1994	Several neurotransmitter receptor antagonists inhibited induction of HSP70 produced by phencyclidine (50 mg/kg): haloperidol (ED50 = 0.8 mg/kg), clozapine (ED50 = 1 mg/kg), valium (ED50 = 1 mg/kg), SCH 23390 (ED50 = 7 mg/kg) and muscimol (ED50 = 3 mg/kg).	Muscimol	229-237	heat shock protein family A (Hsp70) member 4	Homo sapiens	69-74
8012820-0	1994	Injection of bicuculline elicits firing of luteinizing hormone releasing hormone pulse generator in muscimol-treated ovariectomized rats.	Muscimol	100-108	gonadotropin releasing hormone 1	Rattus norvegicus	43-80
8055340-1	1994	The GABA agonist muscimol, injected into the depressor area of the caudal ventrolateral medulla, increased blood pressure and increased the expression of the immediate early gene c-fos in the rostral ventral medulla (RVM) of the rat.	Muscimol	17-25	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	179-184
8055340-2	1994	The number of Fos-immunoreactive (Fos-IR) neurons seen in the RVM was increased 3-fold after muscimol compared to Fos-IR after vehicle treatment.	Muscimol	93-101	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	14-17
8055340-2	1994	The number of Fos-immunoreactive (Fos-IR) neurons seen in the RVM was increased 3-fold after muscimol compared to Fos-IR after vehicle treatment.	Muscimol	93-101	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	34-37
8055340-2	1994	The number of Fos-immunoreactive (Fos-IR) neurons seen in the RVM was increased 3-fold after muscimol compared to Fos-IR after vehicle treatment.	Muscimol	93-101	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	34-37
8055340-5	1994	Fos-IR neurons were also identified in the intermediolateral cell column of the thoracic spinal cord after muscimol injection, but were rarely observed in this area after vehicle treatment.	Muscimol	107-115	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	0-3
8022517-6	1994	The GABAA receptor agonist muscimol (10 microM) stimulated a rapid but transient release of GnRH.	Muscimol	27-35	gonadotropin releasing hormone 1	Mus musculus	92-96
8058123-4	1994	In the fully kindled group, the binding over the complete range of tested [3H]muscimol concentrations was significantly increased by 30-50% in the fascia dentata, while the binding was significantly decreased by 10-25% in the CA1 area.	Muscimol	78-86	carbonic anhydrase 1	Rattus norvegicus	226-229
8149889-0	1994	Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain.	Muscimol	56-64	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	28-33
7813651-0	1994	Reduction of GABAA receptor binding of [3H]muscimol in the barrel field of mice after peripheral denervation: transient and long-lasting effects.	Muscimol	43-51	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	13-18
7813651-1	1994	The effect of peripheral sensory deprivation upon GABAA receptor binding of [3H]muscimol was investigated in the barrel cortex--cortical representation of mystacial vibrissae of mice--by means of in vitro quantitative autoradiography.	Muscimol	80-88	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	50-55
8149889-2	1994	The effect of muscimol, a GABAA receptor agonist, on the basic metabolic activity was investigated in the mouse brain and was correlated with its receptor occupancy.	Muscimol	14-22	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	26-31
8149889-5	1994	On the other hand, the GABAA receptor occupancy of muscimol was determined by using the values of the unbound drug concentration in the brain tissue and the receptor dissociation constant based on the in vitro binding experiments using the dissociated brain cells.	Muscimol	51-59	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	23-28
8149889-7	1994	A linear relationship was observed between the GABAA receptor occupancy of muscimol and the decrease in the cerebral glucose utilization.	Muscimol	75-83	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	47-52
8026706-3	1994	Ginsenoside Rb1 Rb2, Rc, Re, Rf and Rg1 inhibited the specific [3H]muscimol binding to the high-affinity site.	Muscimol	67-75	protein phosphatase 1 regulatory subunit 3A	Homo sapiens	36-39
7770620-3	1994	Several neurotransmitter antagonists, including haloperidol, clozapine, SCH-22390, diazepam, and muscimol, inhibited induction of HSP70 produced by PCP.	Muscimol	97-105	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	130-135
8115020-0	1993	GABA-A agonist muscimol inhibits stimulated vasopressin release in the posterior pituitary of Sprague-Dawley, Wistar, Wistar-Kyoto and spontaneously hypertensive rats.	Muscimol	15-23	arginine vasopressin	Rattus norvegicus	44-55
8314180-3	1994	Pretreatment of brain membranes with Triton X-100 or phospholipase A2 increased [3H]GABA and [3H]muscimol binding in the frontal cortex and cerebellum, whereas these treatments significantly decreased [3H]SR 95531 binding.	Muscimol	97-105	phospholipase A2 group IB	Homo sapiens	53-69
8404645-5	1993	This effect was mimicked by the GABAA receptor agonist, muscimol, and was blocked by the selective antagonist, bicuculline.	Muscimol	56-64	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	32-37
8404645-6	1993	The stimulatory effect of muscimol on LHRH secretion was synergistic with low concentrations of [K+].	Muscimol	26-34	gonadotropin releasing hormone 1	Mus musculus	38-42
8115020-8	1993	Muscimol inhibited in a dose-dependent manner the stimulated release of vasopressin, with an ED50 about 3 microM.	Muscimol	0-8	arginine vasopressin	Rattus norvegicus	72-83
8264847-0	1993	Chronic administration of muscimol and pentobarbital decreases gonadotropin-releasing hormone mRNA levels in the male rat hypothalamus determined by quantitative in situ hybridization.	Muscimol	26-34	gonadotropin releasing hormone 1	Rattus norvegicus	63-93
8117237-4	1993	A low subeffective dose of muscimol (0.5 mg/kg) potentiated the retention-impairing effect of beta-endorphin (1.0 microgram/kg).	Muscimol	27-35	pro-opiomelanocortin-alpha	Mus musculus	94-108
8264847-6	1993	The present results, together with previous data, indicate that the administration of pentobarbital or muscimol can inhibit not only the release of GnRH but also the gene expression of the neuropeptide as evaluated by mRNA level measurements.	Muscimol	103-111	gonadotropin releasing hormone 1	Rattus norvegicus	148-152
1282920-4	1992	In a previous study, we have examined the developmental expression of binding sites for [3H]muscimol, which binds with high affinity to the beta subunits of the GABAA/benzodiazepine (GABAA/BZ) receptor.	Muscimol	92-100	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	161-166
8101728-6	1993	Effects of both muscimol and baclofen on NAT activity were inhibited by GABA-A antagonists, bicuculline and picrotoxin, and the effect of baclofen was unaffected by the GABA-B selective antagonist, CGP 35348.	Muscimol	16-24	arylamine N-acetyltransferase, liver isozyme	Gallus gallus	41-44
8353606-2	1993	The GABA-evoked change of [Ca]i was mimicked by muscimol and not by baclofen, but was only minimally affected by picrotoxin or bicuculline, indicating that this effect of GABA is not likely to be mediated by activation of GABAB receptor or by a conventional chloride-linked GABAA receptor.	Muscimol	48-56	carbonic anhydrase 1	Rattus norvegicus	27-31
8447494-5	1993	Suppression of tonic activity of RVLM neurons by bilateral injection of muscimol in the RVLM showed that the pressor response produced by ANG II antagonist injection in the CVLM required the integrity of rostral pressor neurons.	Muscimol	72-80	angiotensinogen	Rattus norvegicus	138-144
8101728-4	1993	Systemic or intravitreal administration of muscimol, a GABA-A receptor agonist, to light-exposed chicks at the beginning of the dark phase of the light/dark cycle increased retinal melatonin levels and the activity of serotonin N-acetyltransferase (NAT), a key regulatory enzyme of the melatonin biosynthetic pathway.	Muscimol	43-51	aralkylamine N-acetyltransferase	Gallus gallus	218-247
8101728-4	1993	Systemic or intravitreal administration of muscimol, a GABA-A receptor agonist, to light-exposed chicks at the beginning of the dark phase of the light/dark cycle increased retinal melatonin levels and the activity of serotonin N-acetyltransferase (NAT), a key regulatory enzyme of the melatonin biosynthetic pathway.	Muscimol	43-51	arylamine N-acetyltransferase, liver isozyme	Gallus gallus	249-252
8396216-1	1993	The role of GABA neurons in the control of pulsatile release of LHRH was investigated by checking the effect of the GABAA receptor agonist, muscimol, and antagonist, bicuculline, on the electrical activity of the luteinizing hormone-releasing hormone (LHRH) pulse generator in the ovariectomized rat fitted with chronically implanted electrode arrays in the medial basal hypothalamus.	Muscimol	140-148	gonadotropin releasing hormone 1	Rattus norvegicus	64-68
8396216-1	1993	The role of GABA neurons in the control of pulsatile release of LHRH was investigated by checking the effect of the GABAA receptor agonist, muscimol, and antagonist, bicuculline, on the electrical activity of the luteinizing hormone-releasing hormone (LHRH) pulse generator in the ovariectomized rat fitted with chronically implanted electrode arrays in the medial basal hypothalamus.	Muscimol	140-148	gonadotropin releasing hormone 1	Rattus norvegicus	213-250
8097410-3	1993	Muscimol (50 microM) decreased preprosomatostatin mRNA levels, by 25% after 4 h and 30% after 24 h treatment.	Muscimol	0-8	somatostatin	Homo sapiens	31-49
7870943-1	1993	Post-training administration of the GABA-A and GABA-B receptor agonists muscimol and baclofen dose-dependently impaired retention of an inhibitory avoidance response in C57 mice, while improving memory consolidation in the DBA strain.	Muscimol	72-80	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	36-42
1282920-4	1992	In a previous study, we have examined the developmental expression of binding sites for [3H]muscimol, which binds with high affinity to the beta subunits of the GABAA/benzodiazepine (GABAA/BZ) receptor.	Muscimol	92-100	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	183-188
1305960-3	1992	Similar rises in NAT activity were observed following intraocular treatment of ether-anesthetized chickens with muscimol, baclofen and GABA.	Muscimol	112-120	arylamine N-acetyltransferase, liver isozyme	Gallus gallus	17-20
1282920-15	1992	The adult distribution of beta 2 and beta 3 cRNA probes showed good spatial correspondence with the known GABAA receptor beta subunit markers, [3H]-muscimol and the mAb 62-3G1 antibody, each being present within the granule cell layer.	Muscimol	148-156	hemoglobin, beta adult minor chain	Mus musculus	26-43
1324773-2	1992	Incubation of synaptoneurosomes with phospholipase A2 decreased muscimol-induced 36Cl- uptake.	Muscimol	64-72	phospholipase A2 group IB	Rattus norvegicus	37-53
1325030-5	1992	Membranes from immortalized hypothalamic (GT1-7) neurons bound [3H]muscimol but not [3H]flunitrazepam.	Muscimol	67-75	retinoic acid induced 1	Mus musculus	42-47
1336079-2	1992	Muscimol, a GABAA receptor agonist, at doses of 0.25 to 1.0 mg/kg, affected each SIA differently, suppressed PSY-SIA at 0.25 mg/kg but tended to potentiate it at 1.0 mg/kg, potentiated SW-SIA dose-dependently and did not affect FS-SIA at the doses employed.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	12-17
1324773-3	1992	Arachidonic acid, the major unsaturated fatty acid released by phospholipase A2, also inhibited muscimol-induced 36Cl uptake.	Muscimol	96-104	phospholipase A2 group IB	Rattus norvegicus	63-79
1324773-5	1992	The effect of arachidonic acid on muscimol responses was inhibited by bovine serum albumin (BSA), and BSA enhanced muscimol responses directly, indicating the generation of endogenous arachidonic acid in the synaptoneurosome preparation.	Muscimol	34-42	albumin	Rattus norvegicus	77-90
1319326-4	1992	Muscimol, a GABA-A receptor agonist, increased serum PRL concentrations in 16-day-old rats.	Muscimol	0-8	prolactin	Rattus norvegicus	53-56
1319326-5	1992	By contrast, in rats 30 days of age, muscimol induced a significant decrease in PRL levels.	Muscimol	37-45	prolactin	Rattus norvegicus	80-83
1375285-7	1992	GABA-activated chloride currents and muscimol-induced current responses were similarly potentiated on exposure to VIP, suggesting a synergistic interaction between VIP and GABAA receptor mechanisms.	Muscimol	37-45	vasoactive intestinal peptide	Rattus norvegicus	114-117
1463371-2	1992	Swim-stress, the GABAB agonist baclofen and the GABAA agonist muscimol raised the threshold of withdrawal reactions to nociceptive stimulation.	Muscimol	62-70	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	48-53
1375285-7	1992	GABA-activated chloride currents and muscimol-induced current responses were similarly potentiated on exposure to VIP, suggesting a synergistic interaction between VIP and GABAA receptor mechanisms.	Muscimol	37-45	vasoactive intestinal peptide	Rattus norvegicus	164-167
1309346-7	1992	The effect on hCG secretion was mimicked by the GABA-A receptor agonist muscimol (P less than 0.002), but under the experimental conditions used (multiple pulses; 1 microM), only the beta mRNA was increased.	Muscimol	72-80	hypertrichosis 2 (generalised, congenital)	Homo sapiens	14-17
1319167-2	1992	In vitro, phospholipase A2 (PLA2) inhibited muscimol-induced 36Cl- uptake in cerebral cortical synaptoneurosomes.	Muscimol	44-52	phospholipase A2 group IB	Homo sapiens	10-26
1319167-2	1992	In vitro, phospholipase A2 (PLA2) inhibited muscimol-induced 36Cl- uptake in cerebral cortical synaptoneurosomes.	Muscimol	44-52	phospholipase A2 group IB	Homo sapiens	28-32
1319167-8	1992	In contrast, Mg2+, which blocks Ca2+ channels, enhanced muscimol-induced 36Cl- uptake, consistent with its neuroprotective effects.	Muscimol	56-64	carbonic anhydrase 2	Homo sapiens	32-35
19912829-5	1991	Chronic treatment with muscimol and clonazepam also induced a significant decrease in POMC mRNA level in the pars intermedia of the pituitary.	Muscimol	23-31	proopiomelanocortin	Rattus norvegicus	86-90
1648524-1	1991	Interactions between GABAA and GABAB receptors were studied using muscimol-stimulated uptake of 36Cl- by membrane vesicles from mouse cerebellum.	Muscimol	66-74	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	21-26
1723952-8	1991	Similarly, 50 nmol muscimol blocked the rise in both MAP and HR induced by 15 nmol thyrotropin-releasing hormone.	Muscimol	19-27	thyrotropin releasing hormone	Rattus norvegicus	83-112
1661211-1	1991	The neurobehavioral responsivity to peripherally injected muscimol, a gamma-aminobutyric acid-A (GABA-A) agonist, was assessed in infant (14-day-old), weanling (20-day-old) and young adult (53-day-old) outbred male mice.	Muscimol	58-66	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	97-103
1655526-2	1991	Recombinant receptors composed of alpha 4, beta 2 and gamma 2 subunit bind with high affinity the GABA agonist [3H]muscimol and the benzodiazepine "alcohol antagonist" [3H]Ro 15-4513, but fail to bind benzodiazepine agonists.	Muscimol	115-123	crystallin, gamma E	Rattus norvegicus	54-61
1648524-2	1991	Baclofen inhibited muscimol-stimulated 36Cl- uptake and this action was more pronounced with longer flux times (30 vs. 3 s) and after predesensitization of GABAA receptors.	Muscimol	19-27	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	156-161
2323158-0	1990	Butyrylcholinesterase fluctuation in male albino rats with intracerebroventricular injection of gamma aminobutyric acid, muscimol, and picrotoxin.	Muscimol	121-129	butyrylcholinesterase	Rattus norvegicus	0-21
1647705-4	1991	Ethanol increased the chloride conductance produced by the GABAA agonists muscimol, isoguvacine, imidazolacetic acid and amino-propane sulfonic acid and this action of ethanol was blocked by phaclofen.	Muscimol	74-82	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	59-64
1676174-3	1991	The stimulation of locomotor activity produced by the bilateral injection into the SI/LPO of 0.5 microgram of AMPA, a potent quisqualic acid receptor agonist, was antagonized by the coinjection of muscimol (25 ng).	Muscimol	197-205	lactoperoxidase	Homo sapiens	86-89
2172778-1	1990	GABAA receptor agonists such as GABA and muscimol produced desensitization of GABAA receptor-gated Cl- channels.	Muscimol	41-49	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	0-5
2172778-1	1990	GABAA receptor agonists such as GABA and muscimol produced desensitization of GABAA receptor-gated Cl- channels.	Muscimol	41-49	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	78-83
2170800-3	1990	In addition, muscimol offset the elevation of striatal YGG elicited by bestatin, an aminopeptidase inhibitor, which entirely drives the released enkephalins into the metabolic pathway operated by enkephalinase (EC 3.4.24.11).	Muscimol	13-21	membrane metallo endopeptidase	Mus musculus	196-209
2143274-0	1990	Behavioral interactions between muscimol and compounds selective for the D1 and D2 dopamine receptor subtypes.	Muscimol	32-40	dopamine receptor D2	Rattus norvegicus	73-100
1650936-1	1991	The influence of muscimol (a specific gamma-aminobutyric acid-A (GABAA) receptor agonist) on intracellular pH (pHi) was studied in cultured rat astrocytes by means of fluorescence spectrophotometry with BCECF as the H+ indicator.	Muscimol	17-25	glucose-6-phosphate isomerase	Rattus norvegicus	111-114
1650936-3	1991	In a solution containing 22 mM HCO3-, muscimol produced a reversible, concentration-dependent fall in pHi with a maximum of about 0.1-0.15 units.	Muscimol	38-46	glucose-6-phosphate isomerase	Rattus norvegicus	102-105
1650936-4	1991	The muscimol-induced fall in pHi was antagonized by an increase in the external K+ concentration, which suggest that the acidosis is an immediate consequence of a net efflux of HCO3- through GABAA receptor channels rather than an indirect effect caused by a change in membrane potential.	Muscimol	4-12	glucose-6-phosphate isomerase	Rattus norvegicus	29-32
1645612-3	1991	The anti-PTZ effect of 2-APH was significantly attenuated by muscimol, co-infused into SNpr.	Muscimol	61-69	acylaminoacyl-peptide hydrolase	Homo sapiens	25-28
1664340-1	1991	Quantitative autoradiography was used to investigate the distribution and effects of gonadal hormones on [3H] muscimol (specific GABAA receptor ligand) binding in the male Japanese quail brain.	Muscimol	110-118	gamma-aminobutyric acid receptor subunit gamma-4	Coturnix japonica	129-143
1664340-2	1991	In gonadally intact Japanese quail brains, [3H] muscimol revealed a heterogeneous distribution with high GABAA receptor levels in the cerebellum pars granularis (656 fmol/mg wet weight of tissue) and in the pars molecularis (405 fmol/mg wet weight of tissue).	Muscimol	48-56	gamma-aminobutyric acid receptor subunit gamma-4	Coturnix japonica	105-119
1977593-4	1990	The effects of muscimol were antagonized completely by the GABAA antagonist, bicuculline, and the muscarinic acetylcholine receptor antagonist, scopolamine, but not by the benzodiazepine receptor antagonist, flumazenil, when the latter was administered immediately after training.	Muscimol	15-23	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	59-64
2169426-15	1990	In conclusion, the pharmacological features of muscimol I type GABA receptors are partly comparable to those of mammalian GABAA receptors, except for the influences of bicuculline and diazepam: the features of the baclofen type GABA receptor, which did not occur with muscimol I type receptors in the same neurone, were similar to those of GABAB.	Muscimol	47-55	GABA type A receptor-associated protein	Homo sapiens	63-76
2169426-15	1990	In conclusion, the pharmacological features of muscimol I type GABA receptors are partly comparable to those of mammalian GABAA receptors, except for the influences of bicuculline and diazepam: the features of the baclofen type GABA receptor, which did not occur with muscimol I type receptors in the same neurone, were similar to those of GABAB.	Muscimol	268-276	GABA type A receptor-associated protein	Homo sapiens	63-76
2162707-9	1990	Muscimol (MSC), the GABAA agonist, blocked BMI-induced seizures with an ED50 of 0.25 nmol.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	20-25
2331582-0	1990	Central inhibition by gamma-aminobutyric acid and muscimol of the release of vasopressin and oxytocin by an osmotic stimulus in the rat.	Muscimol	50-58	arginine vasopressin	Rattus norvegicus	77-88
2331582-20	1990	The pressor response to HS under the experimental conditions used is due entirely to central sympathetic stimulation and this effect, as well as the release of vasopressin and oxytocin, is blocked by muscimol.	Muscimol	200-208	arginine vasopressin	Rattus norvegicus	160-171
2323158-1	1990	The effects of intracerebroventricular injection of gamma-Aminobutyric acid, muscimol, or picrotoxin have been studied on butyrylcholinesterase (BuChE) activities in the serum and several hypothalamic nuclei using biochemical, histochemical, and cytophotometric techniques, respectively.	Muscimol	77-85	butyrylcholinesterase	Rattus norvegicus	122-143
2323158-1	1990	The effects of intracerebroventricular injection of gamma-Aminobutyric acid, muscimol, or picrotoxin have been studied on butyrylcholinesterase (BuChE) activities in the serum and several hypothalamic nuclei using biochemical, histochemical, and cytophotometric techniques, respectively.	Muscimol	77-85	butyrylcholinesterase	Rattus norvegicus	145-150
2323158-3	1990	Biochemical estimations demonstrated a significant inhibition of BuChE after GABA and muscimol injections, whereas a pronounced stimulation of BuChE was observed after injection of picrotoxin.	Muscimol	86-94	butyrylcholinesterase	Rattus norvegicus	65-70
2323158-6	1990	Only a marginal decrease was observed after injection of GABA in all nuclei, while muscimol induced a very conspicuous decrease of BuChE.	Muscimol	83-91	butyrylcholinesterase	Rattus norvegicus	131-136
2323158-8	1990	Thus it could be concluded that probably GABA and muscimol along with picrotoxin appear to alter BuChE.	Muscimol	50-58	butyrylcholinesterase	Rattus norvegicus	97-102
34502229-0	2021	Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus.	Muscimol	0-8	potassium channel, subfamily K, member 10	Mus musculus	32-38
34268560-7	2021	STN blockade by muscimol injection ameliorated the motor deficit and unmasked cortically evoked inhibition in the GPi.	Muscimol	16-24	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	0-3
34507271-0	2021	GABAA receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice.	Muscimol	23-31	presenilin 1	Mus musculus	133-136
34507271-6	2021	Notably, muscimol, a GABAA receptor agonist, improved odor identification and discrimination behaviors in APP/PS1 mice, reduced MC basal firing activity, and rescued inhibitory circuits along with reducing the Abeta burden in the OB.	Muscimol	9-17	presenilin 1	Mus musculus	110-113
34502229-8	2021	In particular, muscimol, a GABAAR agonist, significantly increased TREK-2 expression and activity, but the effect was reduced in the presence of the GABAAR antagonist bicuculine or TREK-2 inhibitor norfluoxetine.	Muscimol	15-23	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	27-33
34502229-8	2021	In particular, muscimol, a GABAAR agonist, significantly increased TREK-2 expression and activity, but the effect was reduced in the presence of the GABAAR antagonist bicuculine or TREK-2 inhibitor norfluoxetine.	Muscimol	15-23	potassium channel, subfamily K, member 10	Mus musculus	67-73
34502229-8	2021	In particular, muscimol, a GABAAR agonist, significantly increased TREK-2 expression and activity, but the effect was reduced in the presence of the GABAAR antagonist bicuculine or TREK-2 inhibitor norfluoxetine.	Muscimol	15-23	potassium channel, subfamily K, member 10	Mus musculus	181-187
34502229-9	2021	In the whole-cell and single-channel patch configurations, muscimol increased TREK-2 activity, but the muscimol effect disappeared in the N-terminal deletion mutant.	Muscimol	59-67	potassium channel, subfamily K, member 10	Mus musculus	78-84
34502229-10	2021	These results indicate that muscimol directly induces TREK-2 activation through the N-terminus and suggest that muscimol can reduce cellular excitability by activating the TREK-2 channel and by inducing Cl- influx in GABAergic neurons.	Muscimol	28-36	potassium channel, subfamily K, member 10	Mus musculus	54-60
34502229-10	2021	These results indicate that muscimol directly induces TREK-2 activation through the N-terminus and suggest that muscimol can reduce cellular excitability by activating the TREK-2 channel and by inducing Cl- influx in GABAergic neurons.	Muscimol	28-36	potassium channel, subfamily K, member 10	Mus musculus	172-178
34502229-10	2021	These results indicate that muscimol directly induces TREK-2 activation through the N-terminus and suggest that muscimol can reduce cellular excitability by activating the TREK-2 channel and by inducing Cl- influx in GABAergic neurons.	Muscimol	112-120	potassium channel, subfamily K, member 10	Mus musculus	54-60
34502229-10	2021	These results indicate that muscimol directly induces TREK-2 activation through the N-terminus and suggest that muscimol can reduce cellular excitability by activating the TREK-2 channel and by inducing Cl- influx in GABAergic neurons.	Muscimol	112-120	potassium channel, subfamily K, member 10	Mus musculus	172-178
35352582-12	2022	Compared with muscimol acting alone, the joint action of CLP257 and muscimol showed a higher pain threshold and less c-fos expression via upregulation of KCC2 and GABAAalpha2R.	Muscimol	68-76	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	117-122
35618945-11	2022	The muscimol response was compounded with the decreased levels of BDNF and c-Fos in the PFC and the hippocampus.	Muscimol	4-12	brain-derived neurotrophic factor	Rattus norvegicus	66-70
35618945-11	2022	The muscimol response was compounded with the decreased levels of BDNF and c-Fos in the PFC and the hippocampus.	Muscimol	4-12	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	75-80
35352582-12	2022	Compared with muscimol acting alone, the joint action of CLP257 and muscimol showed a higher pain threshold and less c-fos expression via upregulation of KCC2 and GABAAalpha2R.	Muscimol	68-76	solute carrier family 12 member 5	Homo sapiens	154-158
35352582-11	2022	Both muscimol and CLP257 could dose-dependently inhibit mechanical hypersensitivity caused by remifentanil-induced downregulation of GABAAalpha2R and KCC2, respectively.	Muscimol	5-13	solute carrier family 12 member 5	Homo sapiens	150-154
35352582-12	2022	Compared with muscimol acting alone, the joint action of CLP257 and muscimol showed a higher pain threshold and less c-fos expression via upregulation of KCC2 and GABAAalpha2R.	Muscimol	14-22	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	117-122
35352582-12	2022	Compared with muscimol acting alone, the joint action of CLP257 and muscimol showed a higher pain threshold and less c-fos expression via upregulation of KCC2 and GABAAalpha2R.	Muscimol	14-22	solute carrier family 12 member 5	Homo sapiens	154-158
2562066-5	1989	The increase in cytosol GABA-modulin activity in the anterior and posterior hypothalamus of spontaneously hypertensive rats (SHR) and of vasopressin hypertensive rats required much higher doses of muscimol than in normotensive animals showing subsensitivity of GABA(A) receptors in these brain structures.	Muscimol	197-205	arginine vasopressin	Rattus norvegicus	137-148
2575438-0	1989	MIF-1 and Tyr-MIF-1 augment muscimol-stimulated chloride uptake in cerebral cortex.	Muscimol	28-36	predicted gene 4924	Mus musculus	0-5
2575438-0	1989	MIF-1 and Tyr-MIF-1 augment muscimol-stimulated chloride uptake in cerebral cortex.	Muscimol	28-36	predicted gene 4924	Mus musculus	14-19
2551453-7	1989	The GABAA agonist, muscimol (10(-4) M), produced a prolonged inhibition of K+-evoked alpha-MSH release, while the GABAB agonist, baclofen (10(-4) M), was devoid of effect on hypothalamic alpha-MSH release.	Muscimol	19-27	proopiomelanocortin	Rattus norvegicus	85-94
2620959-1	1989	Effect of injection in third ventricle of GABA, the GABA agonist muscimol, and the GABA antagonist picrotoxin on the activities of acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and monoamine oxidase (MAO) in serum and succinic dehydrogenase (SDH) in plasma has been studied.	Muscimol	65-73	acetylcholinesterase	Rattus norvegicus	131-151
2620959-2	1989	Surprisingly, the AChE, BuChE, MAO and SDH enzymes activity were inhibited by GABA and muscimol, while they were enhanced by picrotoxin.	Muscimol	87-95	acetylcholinesterase	Rattus norvegicus	18-22
2620959-2	1989	Surprisingly, the AChE, BuChE, MAO and SDH enzymes activity were inhibited by GABA and muscimol, while they were enhanced by picrotoxin.	Muscimol	87-95	butyrylcholinesterase	Rattus norvegicus	24-29
2620959-2	1989	Surprisingly, the AChE, BuChE, MAO and SDH enzymes activity were inhibited by GABA and muscimol, while they were enhanced by picrotoxin.	Muscimol	87-95	monoamine oxidase A	Rattus norvegicus	31-34
2792064-2	1989	Quantitative film autoradiography was used to study muscimol binding in the CA1 region and 3 other brain areas (dentate gyrus, cerebral cortex, and thalamus).	Muscimol	52-60	carbonic anhydrase 1	Rattus norvegicus	76-79
2753001-2	1989	The effects of small intrathalamic injections of the direct GABA agonist muscimol on the thresholds of pentylenetetrazol (PTZ)-induced seizures and on spontaneous behavior were determined in the rat and compared with the effects of injections of gamma-vinyl-GABA (GVG), an irreversible inhibitor of GABA transaminase.	Muscimol	73-81	4-aminobutyrate aminotransferase	Rattus norvegicus	299-316
2788840-4	1989	Muscimol decreased the concentration of vasopressin in the nucleus of the solitary tract.	Muscimol	0-8	arginine vasopressin	Rattus norvegicus	40-51
2544412-4	1989	Both GABA and muscimol at different concentrations induced an increase in LHRH release, but did not affect the release of arginine vasopressin and oxytocin.	Muscimol	14-22	gonadotropin releasing hormone 1	Homo sapiens	74-78
2544412-6	1989	Muscimol-stimulated LHRH release was not affected by the presence of phentolamine, suggesting that the stimulatory effect of GABA-A receptors on LHRH release is not mediated by interactions with the noradrenergic system.	Muscimol	0-8	gonadotropin releasing hormone 1	Homo sapiens	20-24
2544412-6	1989	Muscimol-stimulated LHRH release was not affected by the presence of phentolamine, suggesting that the stimulatory effect of GABA-A receptors on LHRH release is not mediated by interactions with the noradrenergic system.	Muscimol	0-8	gonadotropin releasing hormone 1	Homo sapiens	145-149
2544412-7	1989	PGE2 has been shown to be a potent secretagogue of LHRH from the median eminence in vitro, and in this model the stimulatory effect of PGE2 was enhanced by muscimol.	Muscimol	156-164	gonadotropin releasing hormone 1	Homo sapiens	51-55
2813488-0	1989	The GABA-A agonist muscimol facilitates muscular twitches and locomotor movements in the neonatal mouse.	Muscimol	19-27	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	4-10
2554616-5	1989	Systemic flumazepil administration contributed to the memory trace reproduction against the background of GABA-A receptors activation by muscimol in the dose of 0.5 mg/kg.	Muscimol	137-145	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	106-112
2813488-1	1989	The effects of nonsedative doses of muscimol, a postsynaptic GABA-A agonist, on neurobehavioral activities in 5- and 11-day-old newborn mice were assessed using an observational point sampling procedure.	Muscimol	36-44	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	61-67
2544811-5	1989	In vitro, the inhibitory effect of muscimol on PRL release from rat hemiadenohypophysis was potentiated in a dose-dependent manner by preincubation with CLOM.	Muscimol	35-43	prolactin	Rattus norvegicus	47-50
2788096-3	1989	Muscimol or 3-aminopropanesulphonic acid (3-APS) was more potent than GABA in enhancing the U1 and U2 waveforms, whereas trans-4-aminocrotonic acid (TACA) was equipotent, its cis isomer (CACA) being less active.	Muscimol	0-8	crystallin gamma D	Homo sapiens	187-191
2546647-2	1989	EB injected subcutaneously increased [3H]muscimol binding in specific subregions of the Ammon"s horn (CA1 and stratum radiatum of CA4) and of the dentate gyrus (dorsal molecular layer).	Muscimol	41-49	carbonic anhydrase 4	Rattus norvegicus	130-133
2535800-0	1989	Growth hormone-releasing factor secretion from fetal hypothalamic cell cultures is modulated by forskolin, phorbol esters, and muscimol.	Muscimol	127-135	growth hormone releasing hormone	Rattus norvegicus	0-31
2535800-8	1989	The gamma-aminobutyric acid (GABA) agonist muscimol (0.1-10 microM) inhibited forskolin-stimulated, but not K+ stimulated, GRF release in a dose-dependent manner.	Muscimol	43-51	growth hormone releasing hormone	Rattus norvegicus	123-126
2535800-10	1989	Muscimol (10 microM) slightly suppressed basal GRF release.	Muscimol	0-8	growth hormone releasing hormone	Rattus norvegicus	47-50
2467978-2	1989	We have found that muscimol, a GABAA receptor agonist, but not baclofen, a GABAB receptor agonist, dose-dependently inhibited caudally directed biting and scratching behavior induced by all three EAA agonists.	Muscimol	19-27	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	31-36
2467978-4	1989	Inhibition by muscimol was blocked with the GABAA receptor antagonist, bicuculline.	Muscimol	14-22	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	44-49
2467978-6	1989	However, muscimol prolonged the tail-flick latency only after presentation of NMDA suggesting a possible antinociceptive effect of GABAA agonists in the presence of agonists at NMDA receptors.	Muscimol	9-17	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	131-136
3287209-8	1988	The effect of renin was also inhibited by GABA, muscimol or taurine injected into the cerebroventricle, in larger doses, or into the preoptic area in smaller doses.	Muscimol	48-56	renin	Rattus norvegicus	14-19
2759416-2	1989	Biochemical estimation demonstrated a significant reduction in MAO enzyme activity after GABA and muscimol injection, whereas picrotoxin produced pronounced increase in the enzyme activity.	Muscimol	98-106	monoamine oxidase A	Rattus norvegicus	63-66
2759416-5	1989	From the above findings, it may be concluded that GABA, muscimol, and picrotoxin regulate the MAO activity, possible mechanisms for which are being discussed.	Muscimol	56-64	monoamine oxidase A	Rattus norvegicus	94-97
2806837-4	1989	Results showed that GABA and muscimol inhibited AChE, BuChE, MAO, and SDH in all the areas while picrotoxin stimulated these enzymes.	Muscimol	29-37	acetylcholinesterase	Rattus norvegicus	48-52
2806837-4	1989	Results showed that GABA and muscimol inhibited AChE, BuChE, MAO, and SDH in all the areas while picrotoxin stimulated these enzymes.	Muscimol	29-37	monoamine oxidase A	Rattus norvegicus	61-64
2855295-3	1988	We demonstrate here that ciprofloxacin displaced a GABA-like substance (muscimol) from the GABA receptor when administered in concentrations of greater than 10(-4) M. These concentrations were lower than those needed by pefloxacin, ofloxacin, and nalidixic acid to reach a concentration that inhibits 50% of binding.	Muscimol	72-80	GABA type A receptor-associated protein	Homo sapiens	91-104
2855295-4	1988	The combination of ciprofloxacin and theophylline was additive in reducing the level of muscimol binding to the GABA receptor, whereas a diclofenac-ciprofloxacin combination had no effect.	Muscimol	88-96	GABA type A receptor-associated protein	Homo sapiens	112-125
2759416-0	1989	Qualitative and quantitative changes in monoamine oxidase activity after acute third ventricle treatment of GABA, muscimol, and picrotoxin in rat.	Muscimol	114-122	monoamine oxidase A	Rattus norvegicus	40-57
2759416-1	1989	The effect of acute IIIrd ventricle injection of GABA, muscimol, and picrotoxin on the activity of monoamine oxidase (MAO) has been investigated in serum and a few hypothalamic nuclei of the rat brain using biochemical, histochemical, and cytophotometric techniques.	Muscimol	55-63	monoamine oxidase A	Rattus norvegicus	99-116
2759416-1	1989	The effect of acute IIIrd ventricle injection of GABA, muscimol, and picrotoxin on the activity of monoamine oxidase (MAO) has been investigated in serum and a few hypothalamic nuclei of the rat brain using biochemical, histochemical, and cytophotometric techniques.	Muscimol	55-63	monoamine oxidase A	Rattus norvegicus	118-121
3237308-2	1988	Muscimol was used as a GABA-A receptor agonist, and baclofen as a GABA-B receptor agonist.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	23-29
2449939-3	1987	In cortex, neither peptide altered [35S]-TBPS binding over a broad dose range, but Tyr-MIF-1 significantly augmented displacement of radioligand binding by the GABA analog muscimol at peptide concentrations of 10(-10) to 10(-7) M; MIF-1 had little effect on muscimol displacement of [35S]-TBPS binding.	Muscimol	172-180	predicted gene 4924	Mus musculus	87-92
20501280-6	1988	When the chloride content of synaptosomes, prepared from rat cerebral cortex, was manipulated, by either exposure to ?-aminobutyric acid, muscimol or to a medium containing reduced levels of chloride, the ability of antibodies against choline acetyltransferase to specifically immunolyse (in the presence of complement) the cholinergic synaptosome population was enhanced.	Muscimol	138-146	choline O-acetyltransferase	Rattus norvegicus	235-260
2449939-5	1987	Thus, Tyr-MIF-1 augments the displacement of [35S]-TBPS binding by the GABA analog muscimol in mouse brain cortical membranes, indicating that this peptide enhances the effects of GABA at the chloride channel as well as at the benzodiazepine receptor.	Muscimol	83-91	predicted gene 4924	Mus musculus	10-15
2447244-3	1988	PLA2 (0.001-0.02 U/mg protein) preincubation decreased pentobarbital-induced 36Cl- efflux and muscimol-induced 36Cl- uptake in rat cerebral cortical synaptoneurosomes.	Muscimol	94-102	phospholipase A2 group IB	Rattus norvegicus	0-4
2449939-3	1987	In cortex, neither peptide altered [35S]-TBPS binding over a broad dose range, but Tyr-MIF-1 significantly augmented displacement of radioligand binding by the GABA analog muscimol at peptide concentrations of 10(-10) to 10(-7) M; MIF-1 had little effect on muscimol displacement of [35S]-TBPS binding.	Muscimol	258-266	predicted gene 4924	Mus musculus	87-92
3682411-7	1987	Muscimol (0.1 microgram) and baclofen (0.05 microgram) injected into the MSN depressed TWA, as indicated by a decrease of the total power.	Muscimol	0-8	moesin	Rattus norvegicus	73-76
3033222-4	1987	The response to muscimol was inhibited by GABAA receptor antagonists such as RU5135 and was enhanced by barbiturates and benzodiazepines.	Muscimol	16-24	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	42-47
3033154-5	1987	Furthermore, treatments with various glycosidases such as glycopeptidase A, beta-galactosidase, and alpha-mannosidase significantly increased the binding of [3H]muscimol.	Muscimol	161-169	galactosidase beta 1	Bos taurus	76-94
3033154-7	1987	Treatment with beta-galactosidase resulted in the disappearance of the low-affinity site for [3H]muscimol binding and in an increase of Bmax of the high-affinity site, without changing the KD value.	Muscimol	97-105	galactosidase beta 1	Bos taurus	15-33
3033154-9	1987	The observation that the enhancement of [3H]muscimol binding by treatments with beta-galactosidase and glycopeptidase A were much higher than that with alpha-mannosidase may also indicate a special importance of the beta-galactosyl residue in the inhibition of GABA receptor binding activity.	Muscimol	44-52	galactosidase beta 1	Bos taurus	80-98
3828822-7	1987	Stimulation of GABA receptors within the NTS by either muscimol or nipecotic acid resulted in an increase in plasma VP levels.	Muscimol	55-63	arginine vasopressin	Rattus norvegicus	116-118
3036541-5	1987	muscimol, a GABAA agonist.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	12-17
2433003-7	1986	Removal of calcium from the culture medium or long-term (48 hr) incubation with 10 microM GABA or muscimol (a mixed GABA-A and GABA-B agonist) significantly reduced POMC mRNA levels.	Muscimol	98-106	proopiomelanocortin	Rattus norvegicus	165-169
20501112-0	1987	The GABA(A) receptor complex in the developing chick optic tectum: characterization of [(3)H]muscimol binding sites.	Muscimol	93-101	gamma-aminobutyric acid type A receptor gamma3 subunit	Gallus gallus	4-20
20501112-1	1987	As part of an ongoing study on the GABA(A) receptor complex in the developing chick optic tectum we describe some properties of the agonist site, as labeled by [(3)H]muscimol, including methodological, kinetic and pharmacological aspects.	Muscimol	166-174	gamma-aminobutyric acid type A receptor gamma3 subunit	Gallus gallus	35-51
20501112-7	1987	The effect of Triton X-100 on the muscimol site in the GABA(A) receptor, increasing the affinity for the radioligand by a factor of 10, and diminishing the efficiency of antagonists, is considered here in terms of structural changes in the receptor, induced by the action of the detergent on the membrane microenvironment.	Muscimol	34-42	gamma-aminobutyric acid type A receptor gamma3 subunit	Gallus gallus	55-71
3026578-8	1986	The GABAA agonist muscimol (10(-7) to 10(-4) M) mimicked the biphasic effect of GABA on alpha-MSH release.	Muscimol	18-26	proopiomelanocortin	Homo sapiens	88-97
3761755-4	1986	Muscimol and AOAA also inhibited decrease in the histamine (HA) level induced by alpha-fluoromethylhistidine (50 mg/kg), a specific inhibitor of histidine decarboxylase.	Muscimol	0-8	histidine decarboxylase	Mus musculus	145-168
3019475-1	1986	The effects on prolactin (Prl) secretion following microinfusion of muscimol or N-methyl-aspartate (NMA) into the medial basal hypothalamus (MBH) of male rats was determined.	Muscimol	68-76	prolactin	Rattus norvegicus	15-24
3019475-2	1986	A highly significant increase in Prl occurred following microinfusion of muscimol (500 pmol) into the arcuate nucleus.	Muscimol	73-81	prolactin	Rattus norvegicus	33-36
6096659-4	1984	Injection of muscimol, a GABA agonist, directly into the SI/LPO produced a dose-dependent decrease in supersensitive locomotor activity at doses that did not alter baseline locomotion.	Muscimol	13-21	lactoperoxidase	Rattus norvegicus	60-63
2873055-1	1986	The effects of beta-alanine, phenibut and muscimol on the activity of the "mirror" (MEF) and primary (PEF) epileptogenic foci were studied in rats on the model of penicillin-induced epilepsy using the direct administration of the drugs into the foci (muscimol only into MEF).	Muscimol	42-50	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	Rattus norvegicus	84-87
2996674-2	1985	The GABAa receptor agonists, muscimol, imidazoleacetic acid and 3-aminopropanesulphonic acid, produced a dose-related potentiation, while bicuculline inhibited the head-twitch.	Muscimol	29-37	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	4-9
2857784-0	1985	Benzodiazepines enhance the muscimol-dependent activation of phospholipase A2 in glioma C6 cells.	Muscimol	28-36	phospholipase A2 group IB	Homo sapiens	61-77
3008013-2	1986	The effect of these treatments on [3H]muscimol binding to the GABA receptor was also determined.	Muscimol	38-46	GABA type A receptor-associated protein	Homo sapiens	62-75
2863325-3	1985	The formation of the decarboxylated product, muscimol, which primarily occurred in a synaptosomal fraction, was dependent on the presence of pyridoxal-5-phosphate (PALP) and was inhibited by (S)-glutamic acid, 3-mercaptopropionic acid (3MPA), aminooxyacetic acid (AOAA), and allyglycine, suggesting that ibotenic acid is a substrate for GAD.	Muscimol	45-53	glutamate decarboxylase 1	Homo sapiens	337-340
2863325-4	1985	The overall decomposition rate for ibotenic acid (8.7 nmol min-1 mg-1 of protein), which apparently embraces other reactions in addition to decarboxylation to muscimol, was higher than the rate of decarboxylation of (S)-glutamic acid (3.2 nmol min-1 mg-1 of protein).	Muscimol	159-167	CD59 molecule (CD59 blood group)	Homo sapiens	59-69
3877311-3	1985	Infusion of muscimol into the region of nucleus accumbens efferent terminals in the substantia innominata and lateral preoptic region (SI/LPO) blocked amphetamine-, but not caffeine- or CRF-stimulated locomotion.	Muscimol	12-20	lactoperoxidase	Rattus norvegicus	138-141
6152472-5	1984	Chlordiazepoxide, diazepam and muscimol inhibited FTA-induced abnormal behaviors.	Muscimol	31-39	farnesyltransferase, CAAX box, alpha	Mus musculus	50-53
6325210-3	1984	Both Trp-P-1 and Trp-P-2 inhibited the specific binding of [3H]diazepam and [3H]muscimol in rat brain membranes mainly by increasing Kd, indicating that these gamma-carbolines bind on benzodiazepine and GABA receptors.	Muscimol	80-88	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	17-24
6717243-1	1984	Growth hormone secretion from pituitaries of neonatal rats was stimulated by gamma-aminobutyric acid (GABA) and the GABA agonist muscimol in vitro.	Muscimol	129-137	gonadotropin releasing hormone receptor	Rattus norvegicus	0-14
6326115-3	1984	Pharmacological studies using drugs that selectively bind to GABAA or GABAB receptors suggest that [3H]muscimol specifically labels a GABAA recognition site.	Muscimol	99-111	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	61-66
6326115-3	1984	Pharmacological studies using drugs that selectively bind to GABAA or GABAB receptors suggest that [3H]muscimol specifically labels a GABAA recognition site.	Muscimol	99-111	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	134-139
6514131-10	1984	This AVP-dependent pressor effect of IVT injected AII was reduced by pretreatment with 100 micrograms of GABA or 50 ng of the GABA agonist muscimol.	Muscimol	139-147	angiotensinogen	Rattus norvegicus	50-53
6514131-11	1984	These doses of GABA and muscimol have previously been shown to reduce the pressor response of IVT administered AII by approximately 60% in untreated rats.	Muscimol	24-32	angiotensinogen	Rattus norvegicus	111-114
6149777-5	1984	According to the same tests TRH was found to be an antagonist of muscimol and an agonist of bicuculline.	Muscimol	65-73	thyrotropin releasing hormone	Mus musculus	28-31
6481454-7	1984	The actions of muscimol were probably mediated by its GABA agonist properties, since microinjection of an irreversible inhibitor of GABA transaminase (gamma-vinyl GABA) into the area of the SN also suppressed kindled seizures.	Muscimol	15-23	4-aminobutyrate aminotransferase	Homo sapiens	132-149
6714309-1	1984	The taurine antagonist TAG was examined for its blocking activity towards the central cardiovascular effects of taurine and muscimol.	Muscimol	124-132	long intergenic non-protein coding RNA 1194	Homo sapiens	23-26
6714309-6	1984	The selectivity of this antagonism is discussed since TAG also shifted to the right the blood pressure dose-response curve obtained with muscimol.	Muscimol	137-145	long intergenic non-protein coding RNA 1194	Homo sapiens	54-57
6320963-5	1984	Although nanomolar concentrations of diazepam alone did not affect PRL release, they did enhance the PRL inhibitory effect of muscimol, a gamma-amino butyric acid (GABA) receptor agonist.	Muscimol	126-134	prolactin	Rattus norvegicus	101-104
6326476-1	1984	GABA receptor activity, as measured by [3H]muscimol binding, was investigated in visual and auditory cortex of 5 weeks old kittens with different visual experience.	Muscimol	43-51	GABA type A receptor-associated protein	Homo sapiens	0-13
6653697-4	1983	Bilateral implantation of tubes containing a muscimol-mannitol mixture into the medial preoptic/anterior hypothalamic (MPO/AH) area abolished pulsatile LH release whereas blood prolactin values were elevated.	Muscimol	45-53	myeloperoxidase	Rattus norvegicus	119-125
6089242-1	1984	Stimulation of GABA receptors (e.g. by progabide, a new GABA receptor antagonist, or by muscimol) enhances the liberation of norepinephrine in limbic forebrain areas of the rat and reduces 5-hydroxytryptamine turnover.	Muscimol	88-96	GABA type A receptor-associated protein	Homo sapiens	15-28
6225034-2	1983	Both apomorphine, a dopamine agonist, and muscimol, a GABA agonist, produced an exaggerated rise in plasma growth hormone levels in the Huntington patients.	Muscimol	42-50	growth hormone 1	Homo sapiens	107-121
6871675-3	1983	IVT-administered muscimol, a potent GABA agonist, also attenuated the pressor effect of IVT AII and hypertonic CSF.	Muscimol	17-25	angiotensinogen	Rattus norvegicus	92-95
6873170-2	1983	treatment with the GABA agonist muscimol (1-100 ng) suppressed the pressor responses to ANG II (100 ng i.c.v.)	Muscimol	32-40	angiotensinogen	Rattus norvegicus	88-94
6298780-4	1983	The capacity of GABA-modulin to decrease the number of sites that bind [3H]muscimol was completely abolished by phosphorylation of this protein with the cAMP-dependent protein kinase but not with the Ca2+-dependent enzyme.	Muscimol	75-83	KIT proto-oncogene receptor tyrosine kinase	Rattus norvegicus	168-182
6644308-1	1983	The reaction of muscimol as amino donor substrate for GABA transaminase (GABA-T) has been studied using enzyme purified from rabbit brain.	Muscimol	16-24	4-aminobutyrate aminotransferase	Homo sapiens	54-71
6644308-1	1983	The reaction of muscimol as amino donor substrate for GABA transaminase (GABA-T) has been studied using enzyme purified from rabbit brain.	Muscimol	16-24	4-aminobutyrate aminotransferase	Homo sapiens	73-79
6644308-5	1983	The rate of spectral change observed on addition of muscimol to ornithine transaminase was extremely slow--at least an order of magnitude slower than that seen with GABA-T.	Muscimol	52-60	4-aminobutyrate aminotransferase	Homo sapiens	165-171
6133770-1	1983	The histamine H2-receptor antagonist cimetidine potently inhibited [3H]muscimol and enhanced [3H]flunitrazepam binding in membranes prepared from several brain regions in the rat, including the dorsal raphe nucleus.	Muscimol	71-79	histamine receptor H 2	Rattus norvegicus	4-25
6653697-9	1983	The inhibitory effect of locally implanted muscimol into the MPO/AH also supports this hypothesis.	Muscimol	43-51	myeloperoxidase	Rattus norvegicus	61-67
7284804-1	1981	Glutamate decarboxylase (GAD) activity and GABA levels, determined with a [3H]muscimol radioreceptor assay, were found to be significantly higher in cerebral blood vessels from the piaarachnoid membrane as compared to extracranial vessels (aorta, mesenteric and femoral arteries, and vena cava).	Muscimol	78-86	glutamate-ammonia ligase	Homo sapiens	0-23
7139278-4	1982	Diazepam (10 microM) induced only an inhibitory effect whereas muscimol (1 microM) stimulated Met-enkephalin release.	Muscimol	63-71	proopiomelanocortin	Homo sapiens	94-108
6279240-2	1982	Nonidet P-40, a non-ionic detergent, was found to be an effective solubilizing agent, since it caused no interference on the receptor binding assay, yielded a [3H]muscimol binding protein with a high specific activity and no aggregation, and preserved good stability of the solubilized fraction.	Muscimol	163-171	septin 3	Rattus norvegicus	8-12
6279240-4	1982	The specific [3H]muscimol binding to the soluble fraction obtained by Nonidet P-40 treatment and subsequent ammonium sulfate precipitation, was saturable with KD 13 and 64 nM, and Bmax 3.4 and 1.8 pmol/mg protein, respectively.	Muscimol	17-25	septin 3	Rattus norvegicus	78-82
6292983-2	1982	It was demonstrated that the GABA receptor agonist muscimol potentiated the sedative properties of ethanol, while the opposite effect, a reduction of ethanol-produced sedation, was seen upon administration of the GABA receptor blocking agent picrotoxin.	Muscimol	51-59	GABA type A receptor-associated protein	Homo sapiens	29-42
7146907-4	1982	Blockade of tonic and clonic seizures was also obtained after microinjections of the direct GABA receptor agonist, muscimol, into the midbrain.	Muscimol	115-123	GABA type A receptor-associated protein	Homo sapiens	92-105
6272937-4	1981	Intracerebroventricular administration of D-alanine methionine enkephalin, bombesin and calcitonin significantly suppressed the muscimol-induced gastric acid secretion.	Muscimol	128-136	proenkephalin	Rattus norvegicus	63-73
7284835-3	1981	Infusion of GABA-receptor agonists (muscimol, THIP) in the MRF-DLSC while producing only minor or no motor or behavioural effects, drastically altered apomorphine effects; thus, unilateral infusion of muscimol resulted i tight, head-to-tail ipsiversive circling while bilateral infusion of muscimol converted the apomorphine-syndrome from stereotypy of high-intensity into pure compulsive forward locomotion devoid of sniffing.	Muscimol	36-44	GABA type A receptor-associated protein	Homo sapiens	12-25
7284835-3	1981	Infusion of GABA-receptor agonists (muscimol, THIP) in the MRF-DLSC while producing only minor or no motor or behavioural effects, drastically altered apomorphine effects; thus, unilateral infusion of muscimol resulted i tight, head-to-tail ipsiversive circling while bilateral infusion of muscimol converted the apomorphine-syndrome from stereotypy of high-intensity into pure compulsive forward locomotion devoid of sniffing.	Muscimol	36-44	myelin regulatory factor	Homo sapiens	59-62
7284835-3	1981	Infusion of GABA-receptor agonists (muscimol, THIP) in the MRF-DLSC while producing only minor or no motor or behavioural effects, drastically altered apomorphine effects; thus, unilateral infusion of muscimol resulted i tight, head-to-tail ipsiversive circling while bilateral infusion of muscimol converted the apomorphine-syndrome from stereotypy of high-intensity into pure compulsive forward locomotion devoid of sniffing.	Muscimol	201-209	GABA type A receptor-associated protein	Homo sapiens	12-25
7284835-3	1981	Infusion of GABA-receptor agonists (muscimol, THIP) in the MRF-DLSC while producing only minor or no motor or behavioural effects, drastically altered apomorphine effects; thus, unilateral infusion of muscimol resulted i tight, head-to-tail ipsiversive circling while bilateral infusion of muscimol converted the apomorphine-syndrome from stereotypy of high-intensity into pure compulsive forward locomotion devoid of sniffing.	Muscimol	201-209	myelin regulatory factor	Homo sapiens	59-62
7284835-3	1981	Infusion of GABA-receptor agonists (muscimol, THIP) in the MRF-DLSC while producing only minor or no motor or behavioural effects, drastically altered apomorphine effects; thus, unilateral infusion of muscimol resulted i tight, head-to-tail ipsiversive circling while bilateral infusion of muscimol converted the apomorphine-syndrome from stereotypy of high-intensity into pure compulsive forward locomotion devoid of sniffing.	Muscimol	201-209	GABA type A receptor-associated protein	Homo sapiens	12-25
7284835-3	1981	Infusion of GABA-receptor agonists (muscimol, THIP) in the MRF-DLSC while producing only minor or no motor or behavioural effects, drastically altered apomorphine effects; thus, unilateral infusion of muscimol resulted i tight, head-to-tail ipsiversive circling while bilateral infusion of muscimol converted the apomorphine-syndrome from stereotypy of high-intensity into pure compulsive forward locomotion devoid of sniffing.	Muscimol	201-209	myelin regulatory factor	Homo sapiens	59-62
6113037-4	1981	Muscimol (a GABA receptor agonist) produced a dose-related, biphasic effect on the light-evoked activation of TH, when the drug was injected into the vitreous (intravitreal injection) of dark-adapted rats.	Muscimol	0-8	tyrosine hydroxylase	Rattus norvegicus	110-112
6113037-5	1981	At low doses, (35 and 60 pmol) muscimol enhanced the light-evoked activation of TH, but at higher doses (greater than or equal to 120 pmol) it inhibited the light-evoked increase in enzyme activity.	Muscimol	31-39	tyrosine hydroxylase	Rattus norvegicus	80-82
6113037-12	1981	Incubation of the cells with muscimol resulted in a decrease of TH activity in a concentration-dependent manner.	Muscimol	29-37	tyrosine hydroxylase	Rattus norvegicus	64-66
162520-0	1978	Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist.	Muscimol	57-65	prolactin	Homo sapiens	15-24
6265125-4	1981	GABA-ergic drugs altered enkephalin-induced myoclonic contractions in the following manner: (a) The GABA-mimetic drugs, muscimol, gabaculine and baclofen, decreased DALA-induced myoclonic contractions.	Muscimol	120-128	proenkephalin	Rattus norvegicus	25-35
6261177-0	1981	GABA and muscimol inhibit the release of prolactin from dispersed rat anterior pituitary cells.	Muscimol	9-17	prolactin	Rattus norvegicus	41-50
6261177-1	1981	Prolactin release from columns of dispersed rat anterior pituitary cells was inhibited by GABA and the GABA agonist muscimol.	Muscimol	116-124	prolactin	Rattus norvegicus	0-9
451556-2	1979	This effect was not obtained in other regions of the brainstem and was reversed by the GABA receptor agonist muscimol.	Muscimol	109-117	GABA type A receptor-associated protein	Homo sapiens	87-100
162520-0	1978	Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist.	Muscimol	57-65	growth hormone 1	Homo sapiens	29-43
162520-4	1978	Since muscimol is thought to be a potent and specific gamma-aminobutyric acid agonist, these data indicate that gamma-aminobutyric acid-mediated neural transmission may function to stimulate the release of plasma PRL and GH in human subjects.	Muscimol	6-14	gamma-glutamyl hydrolase	Homo sapiens	221-223
31981675-6	2020	The microinjection of a GABA-A receptor agonist, muscimol (0.01-0.03 microg/rat) into the CA1 region increased the response of an ineffective dose of morphine (0.5 mg/kg, i.p.)	Muscimol	49-57	carbonic anhydrase 1	Rattus norvegicus	90-93
33826955-7	2021	D-amphetamine and PAG D2 receptor-mediated analgesia were inhibited by intra-RVM injection of lidocaine or the GABAA receptor agonist muscimol, indicating a PAG-RVM signaling pathway in this model of analgesia.	Muscimol	134-142	dopamine receptor D2	Mus musculus	22-33
34013540-5	2021	Our results show a significant reduction in local field potential phase coherence between LIP and V4 in low frequencies (4-15 Hz) following muscimol injection into dPL.	Muscimol	140-148	Pearl	Drosophila melanogaster	164-167
33606338-10	2021	Analyses of expression of the neuronal activity-dependent immediate-early gene Arc in medial PFC and adjacent cortical regions confirmed muscimol infusions led to neuronal inactivation in the infralimbic and prelimbic cortices.	Muscimol	137-145	nucleolar protein 3	Rattus norvegicus	79-82
32471158-6	2020	Our findings show that BLA GABAAR activation via muscimol mimicked the previously reported effects of electrical BLA priming on LTP in the perforant path and the ventral hippocampal commissure-CA1 pathways, decreasing CA1 LTP and increasing DG LTP.	Muscimol	49-57	carbonic anhydrase 1	Rattus norvegicus	193-196
32471158-6	2020	Our findings show that BLA GABAAR activation via muscimol mimicked the previously reported effects of electrical BLA priming on LTP in the perforant path and the ventral hippocampal commissure-CA1 pathways, decreasing CA1 LTP and increasing DG LTP.	Muscimol	49-57	carbonic anhydrase 1	Rattus norvegicus	218-221
32471158-7	2020	Furthermore, muscimol application before or after tetanic stimulation of the ventral hippocampal commissure-CA1 pathways attenuated the BLA priming-induced decrease in CA1 LTP.	Muscimol	13-21	carbonic anhydrase 1	Rattus norvegicus	108-111
32471158-7	2020	Furthermore, muscimol application before or after tetanic stimulation of the ventral hippocampal commissure-CA1 pathways attenuated the BLA priming-induced decrease in CA1 LTP.	Muscimol	13-21	carbonic anhydrase 1	Rattus norvegicus	168-171
720385-1	1978	The GABA receptor agonists, GABA and muscimol, increased, while the GABA receptor antagonist, (+)-bicuculline, decreased the affinity of the benzodiazepine receptor for 3H-diazepam.	Muscimol	37-45	GABA type A receptor-associated protein	Homo sapiens	4-17
212248-0	1978	The effect of muscimol on prolactin secretion in male rats.	Muscimol	14-22	prolactin	Rattus norvegicus	26-35
33476077-4	2021	We found that the reversible suppression of RE/RH with muscimol increased avoidance behavior to the open arms of the plus maze as shown by: (a) significant reductions in open arm entries; (b) reductions in the mean duration of time spent in the open arms; and (c) significant increases in retreats during open arm exploration.	Muscimol	55-63	Rh blood group, D antigen	Rattus norvegicus	44-49
32875348-6	2020	The role of the GABA receptors of CeA in the regulation of such behavior was determined by measuring the dose-dependent effects of the GABAa agonist muscimol or the GABAb agonist baclofen bilaterally microinjected into the CeA on the punished cocaine-seeking behavior.	Muscimol	149-157	carcinoembryonic antigen gene family 4	Rattus norvegicus	34-37
31981675-8	2020	Interestingly, the activation of the BLA CB1 receptors by the microinjection of WIN55,212-2 (0.05-0.1 microg/rat) increased the effect of ineffective doses of muscimol (0.01 microg/rat; intra-CA1) and morphine (0.5 mg/kg, i.p.	Muscimol	159-167	cannabinoid receptor 1	Rattus norvegicus	41-44
31981675-10	2020	The obtained results also showed that microinjection of AM251, a cannabinoid CB1 receptor antagonist, (1-2 mug/rat) into the BLA reversed the synergistic effect of muscimol and morphine, improving memory consolidation.	Muscimol	164-172	cannabinoid receptor 1	Rattus norvegicus	77-80
31981675-11	2020	It should be noted that the intra-CA1 microinjection of muscimol, intra-BLA microinjection of WIN55,212-2 or AM251 alone could not affect memory consolidation.	Muscimol	56-64	carbonic anhydrase 1	Rattus norvegicus	34-37
31511975-9	2019	When the neuroendocrine response to stress was explored, intra-dlPAG infusion of muscimol prior to stress decreased Fos expression in the paraventricular nucleus and serum corticosterone levels.	Muscimol	81-89	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	116-119
31176893-2	2019	In the present study, we analyzed the effects of GABA type A receptor agonist (muscimol) or antagonist (bicuculline) on molecular mechanisms governing GnRH/LH secretion in follicular-phase sheep.	Muscimol	79-87	Progonadoliberin-1	Ovis aries	151-155
31618533-11	2019	The injection of muscimol significantly decreased preproorexin mRNA in the hypothalamus.	Muscimol	17-25	hypocretin neuropeptide precursor	Homo sapiens	50-62
31377402-9	2019	In addition, NMDAr-independent long-term depression (LTD) could not be induced in VCD-mice, which was rescued by the co-application of 8-OH-DPAT with DOI or the GABAA receptor agonist muscimol.	Muscimol	184-192	glutamate receptor, ionotropic, NMDA1 (zeta 1)	Mus musculus	13-18
31638891-5	2019	In the control group, muscimol microinjected into the NRM increased significantly the frequency of CSD-evoked direct current shift and Fos-IR neurons in the TNC.	Muscimol	22-30	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	135-138
31136029-9	2019	The SON AVP neurones that responded to muscimol appeared to be viable and expressed KCC2 and beta-actin.	Muscimol	39-47	solute carrier family 12 member 5	Rattus norvegicus	84-88
31136029-9	2019	The SON AVP neurones that responded to muscimol appeared to be viable and expressed KCC2 and beta-actin.	Muscimol	39-47	actin, beta	Rattus norvegicus	93-103
31136029-13	2019	Blocking NKCC1 using bumetanide had less of an effect on the muscimol-induced Cl- influx in Eu rat neurones compared to the KCC2 antagonist.	Muscimol	61-69	solute carrier family 12 member 2	Rattus norvegicus	9-14
31176893-3	2019	METHODS: ELISA technique was used to investigate the effects of muscimol and/or bicuculline on levels of post-translational products of genes encoding GnRH ligand and GnRH receptor (GnRHR) in the preoptic area (POA), anterior (AH) and ventromedial (VMH) hypothalamus, stalk/median eminence (SME), and GnRHR in the anterior pituitary (AP).	Muscimol	64-72	gonadotropin-releasing hormone receptor	Ovis aries	167-180
31176893-3	2019	METHODS: ELISA technique was used to investigate the effects of muscimol and/or bicuculline on levels of post-translational products of genes encoding GnRH ligand and GnRH receptor (GnRHR) in the preoptic area (POA), anterior (AH) and ventromedial (VMH) hypothalamus, stalk/median eminence (SME), and GnRHR in the anterior pituitary (AP).	Muscimol	64-72	gonadotropin-releasing hormone receptor	Ovis aries	182-187
31176893-3	2019	METHODS: ELISA technique was used to investigate the effects of muscimol and/or bicuculline on levels of post-translational products of genes encoding GnRH ligand and GnRH receptor (GnRHR) in the preoptic area (POA), anterior (AH) and ventromedial (VMH) hypothalamus, stalk/median eminence (SME), and GnRHR in the anterior pituitary (AP).	Muscimol	64-72	gonadotropin-releasing hormone receptor	Ovis aries	301-306
31176893-6	2019	RESULTS: The study demonstrated that muscimol and bicuculline significantly decreased or increased GnRH biosynthesis in all analyzed structures, respectively, and led to analogous changes in plasma LH concentration.	Muscimol	37-45	Progonadoliberin-1	Ovis aries	99-103
31176893-7	2019	Similar muscimol- and bicuculline-related alterations were observed in levels of GnRHR.	Muscimol	8-16	gonadotropin-releasing hormone receptor	Ovis aries	81-86
31176893-8	2019	However, the expression of Kiss 1 and Kiss1r mRNAs in selected POA-hypothalamic areas of either muscimol- and bicuculline-treated animals remained unaltered.	Muscimol	96-104	metastasis-suppressor KiSS-1	Ovis aries	27-33
31176893-8	2019	However, the expression of Kiss 1 and Kiss1r mRNAs in selected POA-hypothalamic areas of either muscimol- and bicuculline-treated animals remained unaltered.	Muscimol	96-104	kiSS-1 receptor	Ovis aries	38-44
31235467-7	2019	Muscimol injection into the BLA decreased the frequency of the latter type of approach behavior, indicating that BLA inactivation reduced avoidance to the CS.	Muscimol	0-8	citrate synthase	Rattus norvegicus	155-157
31235467-8	2019	The muscimol injection into the BLA also significantly increased the consumption of the CS.	Muscimol	4-12	citrate synthase	Rattus norvegicus	88-90
31235467-9	2019	Lick microstructure analysis demonstrated that intra-BLA muscimol significantly increased licking burst number and size, indicating that BLA inactivation attenuated aversion to the CS as large burst licking is an indicator of high palatability.	Muscimol	57-65	citrate synthase	Rattus norvegicus	181-183
31235467-10	2019	These results suggest that the increase in CS consumption with intra-BLA muscimol injection was due to alterations in approach and aversive responses to the CS.	Muscimol	73-81	citrate synthase	Rattus norvegicus	43-45
31235467-10	2019	These results suggest that the increase in CS consumption with intra-BLA muscimol injection was due to alterations in approach and aversive responses to the CS.	Muscimol	73-81	citrate synthase	Rattus norvegicus	157-159
31231197-9	2019	In a separate cohort of mice, we apply muscimol injections to silence the dorsal CA1 region of the hippocampus and show that the use of the spatial strategy in the PPT relies on the integrity of the dorsal hippocampus.	Muscimol	39-47	carbonic anhydrase 1	Mus musculus	81-84
31008485-6	2019	Under the treatment of GABAA-R agonist muscimol, the I-V curves of both the hippocampal CA1 and CA3 neurons of alpha7 KO mice shifted towards depolarizing direction obviously, compared with those of wild type mice.	Muscimol	39-47	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	23-28
30789290-0	2019	Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus.	Muscimol	85-93	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	43-49
30789290-3	2019	AIMS: The aim of the present study was to investigate: 1) 8-OH-DPAT (5-HT1A agonist), AS19 (5-HT7 agonist) and muscimol (GABA-A agonist) on memory retrieval and state of memory, 2) cross state-dependent learning between 8-OH-DPAT and/or AS19 and muscimol.	Muscimol	111-119	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	121-127
30789290-13	2019	Pre-test administration of a selective GABA-A receptor antagonist, bicuculline, 5 min before muscimol, 8-OH-DPAT and AS19 dose-dependently inhibited muscimol-, 8-OH-DPAT- and AS19-induced SDL, respectively.	Muscimol	93-101	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	39-45
30789290-13	2019	Pre-test administration of a selective GABA-A receptor antagonist, bicuculline, 5 min before muscimol, 8-OH-DPAT and AS19 dose-dependently inhibited muscimol-, 8-OH-DPAT- and AS19-induced SDL, respectively.	Muscimol	149-157	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	39-45
30789290-14	2019	CONCLUSIONS: The results strongly revealed a cross SDL among 8-OH-DPAT and/or AS19 and muscimol in the dorsal hippocampal CA1 regions.	Muscimol	87-95	carbonic anhydrase 1	Mus musculus	122-125
30825581-9	2019	Paired stimulation of mPFC and whiskers revealed an inhibitory effect at short intervals (<100 ms), which was mediated by ZI inhibitory neurons since PL stimulation induced response facilitation in the majority of ZI neurons (42%) and muscimol injection into ZI nucleus reduced inhibitory effects, suggesting that the mPFC may inhibit the POm neurons by activation of GABAergic ZI neurons.	Muscimol	238-246	complement factor properdin	Mus musculus	22-26
31008485-6	2019	Under the treatment of GABAA-R agonist muscimol, the I-V curves of both the hippocampal CA1 and CA3 neurons of alpha7 KO mice shifted towards depolarizing direction obviously, compared with those of wild type mice.	Muscimol	39-47	carbonic anhydrase 1	Mus musculus	88-91
31008485-6	2019	Under the treatment of GABAA-R agonist muscimol, the I-V curves of both the hippocampal CA1 and CA3 neurons of alpha7 KO mice shifted towards depolarizing direction obviously, compared with those of wild type mice.	Muscimol	39-47	carbonic anhydrase 3	Mus musculus	96-99
30565258-2	2019	Deletion of the GABAA receptor (GABAA R) delta subunit in mice (deltaKO) leads to a drastic reduction in high-affinity muscimol binding in brain sections and to a lower behavioral sensitivity to muscimol than their wild type counterparts.	Muscimol	119-127	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	16-30
30565258-2	2019	Deletion of the GABAA receptor (GABAA R) delta subunit in mice (deltaKO) leads to a drastic reduction in high-affinity muscimol binding in brain sections and to a lower behavioral sensitivity to muscimol than their wild type counterparts.	Muscimol	119-127	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	32-39
30565258-2	2019	Deletion of the GABAA receptor (GABAA R) delta subunit in mice (deltaKO) leads to a drastic reduction in high-affinity muscimol binding in brain sections and to a lower behavioral sensitivity to muscimol than their wild type counterparts.	Muscimol	195-203	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	16-30
30565258-2	2019	Deletion of the GABAA receptor (GABAA R) delta subunit in mice (deltaKO) leads to a drastic reduction in high-affinity muscimol binding in brain sections and to a lower behavioral sensitivity to muscimol than their wild type counterparts.	Muscimol	195-203	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	32-39
30565258-5	2019	Co-expression of the delta subunit with alpha6 and beta2 or beta3 in recombinant (HEK 293) expression leads to the appearance of a slowly dissociating [3 H]muscimol component.	Muscimol	156-164	hemoglobin, beta adult minor chain	Mus musculus	51-56
30565258-5	2019	Co-expression of the delta subunit with alpha6 and beta2 or beta3 in recombinant (HEK 293) expression leads to the appearance of a slowly dissociating [3 H]muscimol component.	Muscimol	156-164	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	Mus musculus	60-65
30565258-7	2019	These data indicate that delta subunit incorporation leads to a dramatic increase in GABAA R muscimol sensitivity.	Muscimol	93-101	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	85-92
30391741-6	2019	LPS treatment significantly increased the duration of pentobarbital-induced LORR in mice treated with benzodiazepine receptor agonists (diazepam and brotizolam) and a GABAA receptor agonist (muscimol) compared to that of mice treated with vehicle.	Muscimol	191-199	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	167-172
31007601-10	2019	Propofol was similar to the GABAA agonist muscimol in inducing nuclear translocation of nuclear factor-E2-related factor 2 (Nrf2) and inhibiting IL-6 and IL-1beta, but not TNF-alpha, production.	Muscimol	42-50	NFE2 like bZIP transcription factor 2	Homo sapiens	124-128
30682212-0	2019	Taurine potentiates the anticonvulsive effect of the GABAA agonist muscimol and pentobarbital in the immature mouse hippocampus.	Muscimol	67-75	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	53-58
30682212-8	2019	SIGNIFICANCE: These observations demonstrate that taurine can indeed enhance the anticonvulsive effects of muscimol and pentobarbital, suggesting that taurine may act as a positive modulator on GABAA receptors.	Muscimol	107-115	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	194-199
29981238-8	2018	Muscimol, baclofen, telmisartan, valsartan, U-73122, chelerythrine chloride, apocynin or tempol pretreatment significantly suppressed the reduction in intercontraction interval induced by central angiotensin II.	Muscimol	0-8	angiotensinogen	Rattus norvegicus	196-210
30015755-3	2019	RESULTS: Bilateral PVN inhibition with muscimol reduced SBP further in urethane-anaesthetized adult LPK rats than in control Lewis rats (-43 +- 4 vs. -18 +- 3 mmHg; P < 0.0001, n = 14), but was not associated with a greater reduction in sympathetic nerve activity (SNA) or improvement in HR or SNA baroreflex function.	Muscimol	39-47	spermine binding protein	Rattus norvegicus	56-59
31227671-3	2019	OBJECTIVE: To investigate the effects of muscimol on axonal growth, synaptic plasticity and behavioral performance in rats after a focal ischemia induced by endothelin-1 (ET-1).	Muscimol	41-49	endothelin 1	Rattus norvegicus	157-169
30128691-5	2018	After adding 3 mumol/L of the GABAA receptor agonist muscimol, PIDs and IDs disappeared, and IIDs remained.	Muscimol	53-61	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	30-35
29981238-9	2018	Post-treatment with muscimol or baclofen also ameliorated the decrease in intercontraction interval induced by central angiotensin II.	Muscimol	20-28	angiotensinogen	Rattus norvegicus	119-133
30377105-3	2018	GABA currents in CA1 and CA3 pyramidal neurons were induced with the selective GABAA-R agonist muscimol and recorded using perforated patch-clamp recording technique.	Muscimol	95-103	carbonic anhydrase 1	Mus musculus	17-20
30377105-3	2018	GABA currents in CA1 and CA3 pyramidal neurons were induced with the selective GABAA-R agonist muscimol and recorded using perforated patch-clamp recording technique.	Muscimol	95-103	carbonic anhydrase 3	Mus musculus	25-28
29634983-2	2018	Indeed, exogenous GABA and muscimol, a GABAAR agonist, exacerbate acute inflammatory hypersensitivity in rodents.	Muscimol	27-35	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	39-45
29167122-5	2018	Consistent with activity of hypothalamic paraventricular nucleus (PVN) neurons supporting basal SNA in ANG II-salt hypertension, inhibition of PVN with the GABA-A receptor agonist muscimol reduced mean arterial pressure (MAP) and integrated sSNA only in the ANG II-HSD group ( P < 0.001).	Muscimol	180-188	angiotensinogen	Rattus norvegicus	103-109
29167122-5	2018	Consistent with activity of hypothalamic paraventricular nucleus (PVN) neurons supporting basal SNA in ANG II-salt hypertension, inhibition of PVN with the GABA-A receptor agonist muscimol reduced mean arterial pressure (MAP) and integrated sSNA only in the ANG II-HSD group ( P < 0.001).	Muscimol	180-188	angiogenin	Rattus norvegicus	103-106
29225001-4	2018	The results showed that post-training intra-CA1 administration of muscimol (0.05 and 0.1 mug/mouse) impaired memory consolidation as evidenced by a decrease in step-down latency on the test day, which was suggestive of drug-produced amnesia.	Muscimol	66-74	carbonic anhydrase 1	Mus musculus	44-47
29225001-8	2018	Interestingly, post-training intra-CA1 co-injection of different doses of GP1a (1, 10 and 100 mug/mouse) along with an effect dose of muscimol (0.05 mug/mouse) significantly intensified impairment of memory consolidation induced by GP1a (10 mug/mouse).	Muscimol	134-142	carbonic anhydrase 1	Mus musculus	35-38
28927958-9	2018	In contrast, muscimol (GABAA-R agonist, 0.3-100muM) and THIP (selective extrasynaptic GABAA-R agonist, 5muM) induced significantly greater current response in Mecp2-null mice, suggesting increased extrasynaptic receptors.	Muscimol	13-21	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	23-30
29341327-7	2018	Microinjection of the GABAA agonist, muscimol, into the dorsal hippocampus impaired (1) retrieval of a place preference after acquisition, (2) extinction of a place preference, and (3) retrieval of extinction.	Muscimol	37-45	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	22-27
28927958-9	2018	In contrast, muscimol (GABAA-R agonist, 0.3-100muM) and THIP (selective extrasynaptic GABAA-R agonist, 5muM) induced significantly greater current response in Mecp2-null mice, suggesting increased extrasynaptic receptors.	Muscimol	13-21	methyl CpG binding protein 2	Mus musculus	159-164
28843666-4	2017	We performed bilateral inactivation of dorsal CA1 with the GABAA agonist muscimol previously to the task.	Muscimol	73-81	carbonic anhydrase 1	Rattus norvegicus	46-49
29074304-5	2018	We show here that treatment with the GABAAR agonist muscimol mediates structural changes that diminish GABAergic synapse strength through postsynaptic and presynaptic plasticity via intracellular Ca2+ stores, ERK and BDNF/TrkB signaling.	Muscimol	52-60	mitogen-activated protein kinase 1	Homo sapiens	209-212
29074304-5	2018	We show here that treatment with the GABAAR agonist muscimol mediates structural changes that diminish GABAergic synapse strength through postsynaptic and presynaptic plasticity via intracellular Ca2+ stores, ERK and BDNF/TrkB signaling.	Muscimol	52-60	brain derived neurotrophic factor	Homo sapiens	217-221
29074304-5	2018	We show here that treatment with the GABAAR agonist muscimol mediates structural changes that diminish GABAergic synapse strength through postsynaptic and presynaptic plasticity via intracellular Ca2+ stores, ERK and BDNF/TrkB signaling.	Muscimol	52-60	neurotrophic receptor tyrosine kinase 2	Homo sapiens	222-226
29074304-7	2018	Concurrent with this structural plasticity, muscimol treatment decreases synaptic currents while enhancing the gamma2 containing benzodiazepine sensitive GABAAR tonic current in an ERK dependent manner.	Muscimol	44-52	mitogen-activated protein kinase 1	Homo sapiens	181-184
29032058-14	2017	In conclusion, the data strongly revealed a cross SDL among ACPA and muscimol in the dorsal hippocampal CA1 regions.	Muscimol	69-77	carbonic anhydrase 1	Mus musculus	104-107
29259493-0	2017	Gamma-aminobutyric acidA receptor agonist, muscimol, increases KiSS-1 gene expression in hypothalamic cell models.	Muscimol	43-51	KiSS-1 metastasis-suppressor	Rattus norvegicus	63-69
29259493-4	2017	Results: Stimulation of the rHypoE8 cells with muscimol significantly increased the level of KiSS-1 messenger (m)RNA expression.	Muscimol	47-55	KiSS-1 metastasis-suppressor	Rattus norvegicus	93-99
29259493-5	2017	The ability of muscimol to increase the level of KiSS-1 mRNA also was observed in the primary cultures of the neuronal cells from the fetal rat brains.	Muscimol	15-23	KiSS-1 metastasis-suppressor	Rattus norvegicus	49-55
29259493-6	2017	The muscimol-induced increase in KiSS-1 mRNA expression was completely inhibited in the presence of the GABAA receptor antagonist.	Muscimol	4-12	KiSS-1 metastasis-suppressor	Rattus norvegicus	33-39
29259493-7	2017	Although muscimol increased the expression of KiSS-1, the natural compound, GABA, failed to induce the expression of KiSS-1 in the rHypoE8 cells.	Muscimol	9-17	KiSS-1 metastasis-suppressor	Rattus norvegicus	46-52
28108357-9	2017	NO donor DETA/NO or GABAAR agonist muscimol could correct the PPI and recover LTD in sigma1R-/- mice.	Muscimol	35-43	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	20-26
28619359-6	2017	EW-mice showed a significant increase in duration of EPSPs and paired-pulse inhibition (PPI) with multi-spike responses of EPSPs and impairment of long-term depression (LTD) induction, which were corrected by GABAAR agonist muscimol.	Muscimol	224-232	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	209-215
28790892-8	2017	Using calcium imaging, we found that fewer P15 VPm neurons could be excited by the GABAa receptor agonist, muscimol, when compared to P14 VPm neurons; this correlated to an increase in KCC2 expression.	Muscimol	107-115	cyclin dependent kinase inhibitor 2B	Homo sapiens	43-46
28790892-8	2017	Using calcium imaging, we found that fewer P15 VPm neurons could be excited by the GABAa receptor agonist, muscimol, when compared to P14 VPm neurons; this correlated to an increase in KCC2 expression.	Muscimol	107-115	solute carrier family 12 member 5	Homo sapiens	185-189
28280900-12	2017	Muscimol, together with insulin, significantly lowered the level of cytosolic Ca2+ and p-mTOR, and decreased the proliferation rate of alphaTC1-6 cells.	Muscimol	0-8	mechanistic target of rapamycin kinase	Mus musculus	89-93
28389208-7	2017	Moreover, the pre-training intra-BLA microinjection of GABA-A receptor agonist, muscimol, at 0.05 and 0.5mug/mouse impaired context-dependent fear memory, while the same doses of GABA-A antagonist, bicuculline, impaired tone-dependent fear memory.	Muscimol	80-88	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	55-61
28389208-7	2017	Moreover, the pre-training intra-BLA microinjection of GABA-A receptor agonist, muscimol, at 0.05 and 0.5mug/mouse impaired context-dependent fear memory, while the same doses of GABA-A antagonist, bicuculline, impaired tone-dependent fear memory.	Muscimol	80-88	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	179-185
28137700-5	2017	We found: (1) VI decreased during unilateral but increased during bilateral dialysis of DAMGO, (2) dialyses of DAMGO destabilized breathing, (3) unilateral dialysis of muscimol increased VI, and (4) dialysis of DAMGO decreased GABA in the effluent mCSF.	Muscimol	168-176	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	248-252
28966579-7	2017	Inhibition of the MS with muscimol pre-treatment attenuated both carbachol-evoked c-Fos-ir and theta activation.	Muscimol	26-34	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	82-87
28108357-9	2017	NO donor DETA/NO or GABAAR agonist muscimol could correct the PPI and recover LTD in sigma1R-/- mice.	Muscimol	35-43	sigma non-opioid intracellular receptor 1	Homo sapiens	85-92
27544874-7	2017	The present results suggest that opioid mechanisms in the CeA are essential for hypertonic NaCl intake when the LPBN inhibitory mechanisms are deactivated or attenuated with injections of muscimol or moxonidine in this area.	Muscimol	188-196	carcinoembryonic antigen gene family 4	Rattus norvegicus	58-61
28108357-10	2017	In addition, the BLA-injection of NMDA, DETA/NO or muscimol could relieve the depressive-like behaviors in sigma1R-/- mice.	Muscimol	51-59	sigma non-opioid intracellular receptor 1	Mus musculus	107-117
27818188-13	2017	In uninjured rats, BDNF reduced membrane-bound KCC2 and the inhibitory effect of the GABAA agonist muscimol.	Muscimol	99-107	brain-derived neurotrophic factor	Rattus norvegicus	19-23
28438981-3	2017	In vivo, peripheral administration of the selective GABAA receptor agonist muscimol evoked spontaneous licking behavior, as well as spinal wide dynamic range (WDR) neuron firing, after pre-conditioning with formalin but had no effect in saline-treated mice.	Muscimol	75-83	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	52-57
27498071-7	2017	Recording of extracellular action potentials in Purkinje cells showed that the inhibitory effect of the GABAA receptor agonist, muscimol, was lost in cerebellar slices prepared from mGlu5-/- mice or from mice treated systemically with MPEP, in line with the reduction in KCC2 expression.	Muscimol	128-136	solute carrier family 12, member 5	Mus musculus	271-275
28039192-9	2017	Pretreatment with muscimol, a GABAA receptor agonist, in NAcSh potentiated SPA produced by orexin-A injection in rostral LH in HA but not in LA rats.	Muscimol	18-26	hypocretin neuropeptide precursor	Rattus norvegicus	91-99
28066142-8	2017	However, in some neurons, application of GABA or muscimol led to membrane depolarization in the IL-1beta-treated rats.	Muscimol	49-57	interleukin 1 beta	Rattus norvegicus	96-104
27634096-8	2016	This possibility is supported by studies demonstrating that neuronal silencing, via incubation with the GABAA receptor agonist muscimol, completely blocks phospho-ERK and BDNF release by each agent.	Muscimol	127-135	Eph receptor B1	Rattus norvegicus	163-166
27634096-8	2016	This possibility is supported by studies demonstrating that neuronal silencing, via incubation with the GABAA receptor agonist muscimol, completely blocks phospho-ERK and BDNF release by each agent.	Muscimol	127-135	brain-derived neurotrophic factor	Rattus norvegicus	171-175
27428822-4	2016	RESULTS: Bilateral intra-ACC microinjections of gamma-aminobutyric acid receptor type A receptor agonist muscimol decreased mechanical hypersensitivity in tumor-bearing mice (n =10).	Muscimol	105-113	anterior capsular cataract	Mus musculus	25-28
27330015-6	2016	The current study used pre-test local microinfusion of muscimol directly into the CA1 region of dorsal hippocampus to temporarily interrupt its function during the respective retrieval phases of both behavioral tasks, in order to compare the contribution of the CA1 to object memory and spatial memory.	Muscimol	55-63	carbonic anhydrase 1	Mus musculus	82-85
27330015-7	2016	Histological analyses revealed that local intra-CA1 injection of muscimol diffused within, and not beyond, the CA1 region of dorsal hippocampus.	Muscimol	65-73	carbonic anhydrase 1	Mus musculus	48-51
27330015-7	2016	Histological analyses revealed that local intra-CA1 injection of muscimol diffused within, and not beyond, the CA1 region of dorsal hippocampus.	Muscimol	65-73	carbonic anhydrase 1	Mus musculus	111-114
27330015-9	2016	Further, we confirmed that the muscimol-induced impairment of CA1 function is temporary.	Muscimol	31-39	carbonic anhydrase 1	Mus musculus	62-65
27330015-10	2016	First, mice that exhibited impaired object memory retrieval immediately after intra-CA1 muscimol, subsequently exhibited unimpaired retrieval of object memory when tested 24h later.	Muscimol	88-96	carbonic anhydrase 1	Mus musculus	84-87
27330015-11	2016	Secondly, a cohort of mice that exhibited impaired object memory retrieval after intra-CA1 muscimol later acquired spatial memory in the MWM comparable to that of control mice.	Muscimol	91-99	carbonic anhydrase 1	Mus musculus	87-90
26216055-6	2016	The systemic preadministration of the GABAA antagonist, bicuculline, and agonist, muscimol, had stronger decreasing effects on FRB and c-Fos-IR cells in IB4-Sap-treated rats than the preadministration of Sal, whereas the opposite effects were observed in Sal- and Bl-Sap-treated rats.	Muscimol	82-90	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	135-140
27222045-9	2016	The addition of GABA and the GABA A type receptor agonist, Muscimol, promoted cell proliferation and inhibited cell apoptosis through the activation of the p38 MAPK and the inhibition of the JNK MAPK signaling pathways.	Muscimol	59-67	mitogen-activated protein kinase 8	Homo sapiens	191-194
27090228-8	2016	Similarly, injection of the subthreshold dose of muscimol (0.125mug/mouse, intra-CA1) decreased the CPP acquisition induced by ACPA.	Muscimol	49-57	carbonic anhydrase 1	Mus musculus	81-84
26358148-5	2015	The GABAA agonist muscimol (0.25 nmol/0.2 mul) injected bilaterally into the CeA abolished the effects of moxonidine into the LPBN on 0.3M NaCl (2.8 +- 1.6 ml/2h) and water intake (3.3 +- 2.3 ml/2h).	Muscimol	18-26	carcinoembryonic antigen gene family 4	Rattus norvegicus	77-80
26691781-3	2016	Further, we show that OR consolidation is attended by an increase of norepinephrine (NE) levels and of the expression of brain derived neurotrophic factor (BDNF) in hippocampus, which are impaired by inactivation of the NTS-PGi-LC pathway by the infusion of muscimol into the NTS.	Muscimol	258-266	brain derived neurotrophic factor	Homo sapiens	121-154
26691781-3	2016	Further, we show that OR consolidation is attended by an increase of norepinephrine (NE) levels and of the expression of brain derived neurotrophic factor (BDNF) in hippocampus, which are impaired by inactivation of the NTS-PGi-LC pathway by the infusion of muscimol into the NTS.	Muscimol	258-266	brain derived neurotrophic factor	Homo sapiens	156-160
26358148-7	2015	Muscimol (0.5 nmol/0.2 mul) into the CeA also abolished 0.3M NaCl (0.1 +- 0.04 ml/4h) and water intake (0.1 +- 0.02 ml/4h) in euhydrated treated with muscimol into the LPBN.	Muscimol	0-8	carcinoembryonic antigen gene family 4	Rattus norvegicus	37-40
26370892-4	2015	Inhibition of the paraventricular nucleus with muscimol completely reversed leptin"s effects.	Muscimol	47-55	leptin	Rattus norvegicus	76-82
26368844-7	2015	Furthermore, the additional effect of muscimol (125ng/rat) on memory impairment induced by WIN55, 212-2 (0.1mug/rat) was prevented by intra-CeA co-injection of bicuculline (200ng/rat).	Muscimol	38-46	carcinoembryonic antigen gene family 4	Rattus norvegicus	140-143
26368844-8	2015	We indicated that stimulating or blocking GAGA(A) receptors in the CeA by muscimol and bicuculline interfere with WIN55, 212-2-induced deficits in memory retention in a PAL task and therefore suggests an interaction between cannabinergic and GABAergic systems of the CeA in memory process.	Muscimol	74-82	carcinoembryonic antigen gene family 4	Rattus norvegicus	67-70
25963561-7	2015	METHODS: In experiment 1, C57Bl/6 mice received post-acquisition dHp infusions of the GABA agonist muscimol.	Muscimol	99-107	Collapsin Response Mediator Protein	Drosophila melanogaster	65-68
25963561-9	2015	RESULTS: Post-acquisition muscimol dose-dependently impaired dPAL and cdPAL performance.	Muscimol	26-34	pal	Drosophila melanogaster	61-65
26344240-0	2015	AT1 receptor blockade in the central nucleus of the amygdala attenuates the effects of muscimol on sodium and water intake.	Muscimol	87-95	angiotensin II receptor, type 1a	Rattus norvegicus	0-3
26344240-1	2015	The blockade of the central nucleus of the amygdala (CeA) with the GABAA receptor agonist muscimol significantly reduces hypertonic NaCl and water intake by sodium-depleted rats.	Muscimol	90-98	carcinoembryonic antigen gene family 4	Rattus norvegicus	53-56
26344240-2	2015	In the present study we investigated the effects of previous injection of losartan, an angiotensin II type-1 (AT1) receptor antagonist, into the CeA on 0.3M NaCl and water intake reduced by muscimol bilaterally injected into the same areas in rats submitted to water deprivation-partial rehydration (WD-PR) and in rats treated with the diuretic furosemide (FURO).	Muscimol	190-198	carcinoembryonic antigen gene family 4	Rattus norvegicus	145-148
26344240-4	2015	Bilateral injections of muscimol (0.2 nmol/0.5 mul, n=8 rats/group) into the CeA in WD-PR-treated rats reduced 0.3M NaCl intake and water intake, and pre-treatment of the CeA with losartan (50 mug/0.5 mul) reversed the inhibitory effect of muscimol.	Muscimol	24-32	carcinoembryonic antigen gene family 4	Rattus norvegicus	77-80
26344240-4	2015	Bilateral injections of muscimol (0.2 nmol/0.5 mul, n=8 rats/group) into the CeA in WD-PR-treated rats reduced 0.3M NaCl intake and water intake, and pre-treatment of the CeA with losartan (50 mug/0.5 mul) reversed the inhibitory effect of muscimol.	Muscimol	24-32	carcinoembryonic antigen gene family 4	Rattus norvegicus	171-174
26344240-5	2015	The negative effect of muscimol on sodium and water intake could also be blocked by pretreatment with losartan microinjected into the CeA in rats given FURO (n=8 rats/group).	Muscimol	23-31	carcinoembryonic antigen gene family 4	Rattus norvegicus	134-137
26344240-7	2015	These results suggest that the deactivation of CeA facilitatory mechanisms by muscimol injection into the CeA is promoted by endogenous angiotensin II acting on AT1 receptors in the CeA, which prevents rats from ingesting large amounts of hypertonic NaCl and water.	Muscimol	78-86	carcinoembryonic antigen gene family 4	Rattus norvegicus	47-50
26344240-7	2015	These results suggest that the deactivation of CeA facilitatory mechanisms by muscimol injection into the CeA is promoted by endogenous angiotensin II acting on AT1 receptors in the CeA, which prevents rats from ingesting large amounts of hypertonic NaCl and water.	Muscimol	78-86	carcinoembryonic antigen gene family 4	Rattus norvegicus	106-109
26344240-7	2015	These results suggest that the deactivation of CeA facilitatory mechanisms by muscimol injection into the CeA is promoted by endogenous angiotensin II acting on AT1 receptors in the CeA, which prevents rats from ingesting large amounts of hypertonic NaCl and water.	Muscimol	78-86	angiotensinogen	Rattus norvegicus	136-150
26344240-7	2015	These results suggest that the deactivation of CeA facilitatory mechanisms by muscimol injection into the CeA is promoted by endogenous angiotensin II acting on AT1 receptors in the CeA, which prevents rats from ingesting large amounts of hypertonic NaCl and water.	Muscimol	78-86	angiotensin II receptor, type 1a	Rattus norvegicus	161-164
26344240-7	2015	These results suggest that the deactivation of CeA facilitatory mechanisms by muscimol injection into the CeA is promoted by endogenous angiotensin II acting on AT1 receptors in the CeA, which prevents rats from ingesting large amounts of hypertonic NaCl and water.	Muscimol	78-86	carcinoembryonic antigen gene family 4	Rattus norvegicus	106-109
25995347-4	2015	Application of the nonspecific GABAA receptor agonist muscimol evoked an outward current of significantly larger amplitude in DMV neurons from diabetic mice than controls.	Muscimol	54-62	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	31-36
26321868-8	2015	Muscimol (100 muM) caused a transient increase of the [Ca(2+)]i in RPE cells regardless of whether Ca(2+) was added to the buffer.	Muscimol	0-8	latexin	Homo sapiens	14-17
26321868-9	2015	Muscimol-induced increases in the [Ca(2+)]i were inhibited by pretreatment with picrotoxin (300 muM) or TPMPA (500 muM).	Muscimol	0-8	latexin	Homo sapiens	96-99
26321868-9	2015	Muscimol-induced increases in the [Ca(2+)]i were inhibited by pretreatment with picrotoxin (300 muM) or TPMPA (500 muM).	Muscimol	0-8	latexin	Homo sapiens	115-118
26110920-9	2015	Using explants, calcium imaging and gramicidin perforated patch clamp techniques we found that GnRH neurons from NKCC1-/- mice retained relatively normal responses to the GABAA agonist muscimol.	Muscimol	185-193	gonadotropin releasing hormone 1	Mus musculus	95-99
26110920-10	2015	However, acute pharmacological inhibition of NKCC1 with bumetanide eliminated the depolarization/calcium response to muscimol in 40% of GnRH neurons from WT mice.	Muscimol	117-125	solute carrier family 12, member 2	Mus musculus	45-50
26110920-10	2015	However, acute pharmacological inhibition of NKCC1 with bumetanide eliminated the depolarization/calcium response to muscimol in 40% of GnRH neurons from WT mice.	Muscimol	117-125	gonadotropin releasing hormone 1	Mus musculus	136-140
26110920-11	2015	In the remaining GnRH neurons, HCO3- mediated mechanisms accounted for the remaining calcium responses to muscimol.	Muscimol	106-114	gonadotropin releasing hormone 1	Mus musculus	17-21
25762286-6	2015	Inhibiting CN neuron action potential firing by local application of the gamma-aminobutyric acid type A (GABA-A) agonist muscimol increased GSWD occurrence up to 37-fold, whereas increasing the frequency and regularity of CN neuron firing with the use of GABA-A antagonist gabazine decimated its occurrence.	Muscimol	121-129	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	73-103
25762286-6	2015	Inhibiting CN neuron action potential firing by local application of the gamma-aminobutyric acid type A (GABA-A) agonist muscimol increased GSWD occurrence up to 37-fold, whereas increasing the frequency and regularity of CN neuron firing with the use of GABA-A antagonist gabazine decimated its occurrence.	Muscimol	121-129	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	105-111
25762286-6	2015	Inhibiting CN neuron action potential firing by local application of the gamma-aminobutyric acid type A (GABA-A) agonist muscimol increased GSWD occurrence up to 37-fold, whereas increasing the frequency and regularity of CN neuron firing with the use of GABA-A antagonist gabazine decimated its occurrence.	Muscimol	121-129	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	255-261
25983020-8	2015	The results indicate that early postnatal and to a lesser extent later postnatal exposure to the GABA-A receptor agonist muscimol increased anxiety-like behavior and stress-induced CORT levels in adults.	Muscimol	121-129	cortistatin	Mus musculus	181-185
25983020-9	2015	Moreover, the early postnatal treatment with muscimol increased depression-like behavior with increasing baseline CORT levels.	Muscimol	45-53	cortistatin	Mus musculus	114-118
24793772-9	2014	Altered protein arginine methylation is also observed when cells are treated with the GABAA agonist muscimol but not an antagonist, bicuculline.	Muscimol	100-108	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	86-91
25550507-3	2015	Muscimol infused intra-CA1 before an extinction training session of contextual fear conditioning (CFC) blocks retrieval but not consolidation of extinction measured 24 h later.	Muscimol	0-8	carbonic anhydrase 1	Homo sapiens	23-26
26631092-4	2015	The results show that GABA as well as the GABA receptor agonists Muscimol (GABAA agonist) and Baclofen (GABAB agonist) caused a decrease in glutamate release in control rats paralleled by a similar reduction in synapsin I phosphorylation.	Muscimol	65-73	synapsin I	Rattus norvegicus	211-221
25091528-6	2015	Fear expression was not affected by this treatment if preceded by memory reactivation 6 h earlier, nor was it affected by suppression of neural activity in the dorsal hippocampus with the GABA-receptor agonist muscimol.	Muscimol	210-218	GABA type A receptor-associated protein	Homo sapiens	188-201
25217880-6	2014	Molecular docking studies also were performed to evaluate intermolecular interactions of the carvacrol and muscimol, as ligands of interleukin-10 and GABAA receptors.	Muscimol	107-115	interleukin 10	Mus musculus	131-145
25644702-6	2015	This muscimol response switch depends on chloride transporters in the muscles analogous to those that control GABA response in mammalian neurons: the chloride accumulator sodium-potassium-chloride-cotransporter-1 (NKCC-1) is required for the early depolarizing muscimol response, while the two chloride extruders potassium-chloride-cotransporter-2 (KCC-2) and anion-bicarbonate-transporter-1 (ABTS-1) are required for the later hyperpolarizing response.	Muscimol	5-13	solute carrier family 12 member 2	Homo sapiens	214-220
25644702-6	2015	This muscimol response switch depends on chloride transporters in the muscles analogous to those that control GABA response in mammalian neurons: the chloride accumulator sodium-potassium-chloride-cotransporter-1 (NKCC-1) is required for the early depolarizing muscimol response, while the two chloride extruders potassium-chloride-cotransporter-2 (KCC-2) and anion-bicarbonate-transporter-1 (ABTS-1) are required for the later hyperpolarizing response.	Muscimol	5-13	solute carrier family 12 member 5	Homo sapiens	349-354
25644702-6	2015	This muscimol response switch depends on chloride transporters in the muscles analogous to those that control GABA response in mammalian neurons: the chloride accumulator sodium-potassium-chloride-cotransporter-1 (NKCC-1) is required for the early depolarizing muscimol response, while the two chloride extruders potassium-chloride-cotransporter-2 (KCC-2) and anion-bicarbonate-transporter-1 (ABTS-1) are required for the later hyperpolarizing response.	Muscimol	261-269	solute carrier family 12 member 2	Homo sapiens	214-220
25482075-7	2015	Moreover, the 5-HT2A agonist reduced the amplitude of the IPSCs evoked by application of the selective GABA agonist, muscimol.	Muscimol	117-125	5-hydroxytryptamine receptor 2A	Rattus norvegicus	14-20
25448432-4	2015	Infusion of the GABA-A agonist muscimol in the left DLS immediately after a single experience of FST prevented and infusion in the left or the right amygdala impaired recall of the acquired levels of immobility in a probe test performed 24h later.	Muscimol	31-39	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	16-22
25466558-6	2014	Using immunocytochemistry and single particle tracking experiments on mouse hippocampal neurons, we show that the agonist muscimol decreases GABA(A)R and gephyrin levels at synapses and accelerates the receptor"s lateral diffusion within 30-120 min of treatment.	Muscimol	122-130	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	141-149
25466558-6	2014	Using immunocytochemistry and single particle tracking experiments on mouse hippocampal neurons, we show that the agonist muscimol decreases GABA(A)R and gephyrin levels at synapses and accelerates the receptor"s lateral diffusion within 30-120 min of treatment.	Muscimol	122-130	gephyrin	Mus musculus	154-162
25466558-9	2014	Surprisingly, the positive allosteric modulator diazepam abolished the regulation induced by muscimol, and this effect was observed on alpha1, alpha2, alpha5 and gamma2 GABA(A)R subunits.	Muscimol	93-101	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	169-177
25217880-6	2014	Molecular docking studies also were performed to evaluate intermolecular interactions of the carvacrol and muscimol, as ligands of interleukin-10 and GABAA receptors.	Muscimol	107-115	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	150-155
25277376-10	2014	Accordantly, activation of GABAergic inhibition by intra-CeA administration of muscimol, a selective GABAA receptors agonist, could inhibit SNL-induced anxiety-like behaviors in neuropathic rats.	Muscimol	79-87	carcinoembryonic antigen gene family 4	Rattus norvegicus	57-60
24710315-4	2014	An intra-CA1 injection of (+)-MK-801 (2 mug/rat) and muscimol (0.5 mug/rat; a GABAA receptor agonist) increased %OAT and %OAE by themselves while not altering the closed arm entries, indicating an anxiolytic-like effect of these drugs.	Muscimol	53-61	carbonic anhydrase 1	Rattus norvegicus	9-12
24755486-6	2014	Secondly, inhibition of the STN by local injections of the GABA agonist, muscimol, suppressed ether-evoked c-fos expression in all target structures.	Muscimol	73-81	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	107-112
24710315-7	2014	The isobologram analysis of these findings suggested a synergistic anxiety-like effect of intra-CA1 (+)-MK-801 and muscimol.	Muscimol	115-123	carbonic anhydrase 1	Rattus norvegicus	96-99
24743647-5	2014	Whole-cell recordings reveal that GABA, muscimol and the anthelmintic piperazine elicit macroscopic currents from UNC-49 receptors that decay in their sustained presence, indicating full desensitization.	Muscimol	40-48	Neur_chan_LBD domain-containing protein;Neur_chan_memb domain-containing protein;Uncharacterized protein	Caenorhabditis elegans	114-120
24606334-7	2014	Microinjection of bicuculline or muscimol in combination with morphine into the CeA increased and decreased TFL, respectively.	Muscimol	33-41	carcinoembryonic antigen gene family 4	Rattus norvegicus	80-83
24904309-5	2014	Inactivation of the STN by muscimol (GABAA receptor agonist) injection also ameliorated parkinsonian signs and suppressed GPi oscillations.	Muscimol	27-35	glucose-6-phosphate isomerase	Homo sapiens	122-125
24904251-6	2014	After temporary paralysis of the hand was induced by reversible inactivation of primary motor cortex using muscimol, grasp-related single-unit activity from the ventral premotor cortex was converted into stimulation patterns delivered in real-time to the cervical spinal gray matter.	Muscimol	107-115	trafficking regulator and scaffold protein tamalin	Homo sapiens	117-122
23792226-4	2013	A unilateral intracranial administration of the GABA agonist muscimol aimed at the VTA resulted in increased number of Fos-positive cells in the EWcp.	Muscimol	61-69	FBJ osteosarcoma oncogene	Mus musculus	119-122
24342568-4	2014	Additionally, a low dose of the GABAA agonist muscimol was used to temporarily inactivate CA1 to observe its effect in extinction.	Muscimol	46-54	carbonic anhydrase 1	Rattus norvegicus	90-93
24342568-6	2014	Moreover, muscimol infused into CA1 before extinction training resulted in impaired extinction and down-regulation of NR2B activity and phosphorylated GluR1 (at Ser845) in CA1, and the expression levels of NR2B and GluR1 were decreased significantly in the basolateral amygdala (BLA).	Muscimol	10-18	carbonic anhydrase 1	Rattus norvegicus	32-35
24342568-6	2014	Moreover, muscimol infused into CA1 before extinction training resulted in impaired extinction and down-regulation of NR2B activity and phosphorylated GluR1 (at Ser845) in CA1, and the expression levels of NR2B and GluR1 were decreased significantly in the basolateral amygdala (BLA).	Muscimol	10-18	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	118-122
24342568-6	2014	Moreover, muscimol infused into CA1 before extinction training resulted in impaired extinction and down-regulation of NR2B activity and phosphorylated GluR1 (at Ser845) in CA1, and the expression levels of NR2B and GluR1 were decreased significantly in the basolateral amygdala (BLA).	Muscimol	10-18	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	151-156
24342568-6	2014	Moreover, muscimol infused into CA1 before extinction training resulted in impaired extinction and down-regulation of NR2B activity and phosphorylated GluR1 (at Ser845) in CA1, and the expression levels of NR2B and GluR1 were decreased significantly in the basolateral amygdala (BLA).	Muscimol	10-18	carbonic anhydrase 1	Rattus norvegicus	172-175
24342568-6	2014	Moreover, muscimol infused into CA1 before extinction training resulted in impaired extinction and down-regulation of NR2B activity and phosphorylated GluR1 (at Ser845) in CA1, and the expression levels of NR2B and GluR1 were decreased significantly in the basolateral amygdala (BLA).	Muscimol	10-18	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	206-210
24342568-6	2014	Moreover, muscimol infused into CA1 before extinction training resulted in impaired extinction and down-regulation of NR2B activity and phosphorylated GluR1 (at Ser845) in CA1, and the expression levels of NR2B and GluR1 were decreased significantly in the basolateral amygdala (BLA).	Muscimol	10-18	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	215-220
24368306-3	2014	Post-training intra-CA1 administration of a GABAA receptor agonist, muscimol (0.05 and 0.1 mug/mouse) dose dependently induced impairment of memory retention.	Muscimol	68-76	carbonic anhydrase 1	Mus musculus	20-23
24368306-4	2014	Pre-test injection of muscimol (0.05 and 0.1 mug/mouse) induced state-dependent retrieval of the memory acquired under post-training muscimol (0.1 mug/mouse, intra-CA1) influence.	Muscimol	22-30	carbonic anhydrase 1	Mus musculus	164-167
24368306-4	2014	Pre-test injection of muscimol (0.05 and 0.1 mug/mouse) induced state-dependent retrieval of the memory acquired under post-training muscimol (0.1 mug/mouse, intra-CA1) influence.	Muscimol	133-141	carbonic anhydrase 1	Mus musculus	164-167
24368306-9	2014	Pre-test intra-CA1 injection of L-NAME (0.25 mug/mouse, intra-CA1) reversed the memory impairment induced by post-training administration of muscimol (0.1 mug/mouse, intra-CA1).	Muscimol	141-149	carbonic anhydrase 1	Mus musculus	15-18
24368306-9	2014	Pre-test intra-CA1 injection of L-NAME (0.25 mug/mouse, intra-CA1) reversed the memory impairment induced by post-training administration of muscimol (0.1 mug/mouse, intra-CA1).	Muscimol	141-149	carbonic anhydrase 1	Mus musculus	62-65
24368306-9	2014	Pre-test intra-CA1 injection of L-NAME (0.25 mug/mouse, intra-CA1) reversed the memory impairment induced by post-training administration of muscimol (0.1 mug/mouse, intra-CA1).	Muscimol	141-149	carbonic anhydrase 1	Mus musculus	62-65
24198228-6	2014	Inhibition of GABAAR endocytosis by muscimol increased both GABAARs and BIG1 at the neuronal surface in a time-dependent fashion, and this increase could be abolished by bicuculline.	Muscimol	36-44	ADP ribosylation factor guanine nucleotide exchange factor 1	Homo sapiens	72-76
24198228-7	2014	Finally, depletion of BIG1 by siRNA inhibited the muscimol-stimulated increase of GABAARs.	Muscimol	50-58	ADP ribosylation factor guanine nucleotide exchange factor 1	Homo sapiens	22-26
21790906-8	2013	Activation of GABAA receptors with muscimol produces a stronger and longer lasting depression of neurotransmission in adolescent mice as compared with adult mice.	Muscimol	35-43	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	14-19
23535348-6	2013	Fos protein immunoreactivity revealed that contextual fear promoted wide activation of the mPFC, which was significantly reduced after intra-DH infusions of muscimol.	Muscimol	157-165	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	0-3
24348338-7	2013	Finally, we locally injected the GABAA agonist Muscimol into layer CA1 of the hippocampus while simultaneously recording somatic activity and SDWs on the same tetrodes.	Muscimol	47-55	carbonic anhydrase 1	Rattus norvegicus	67-70
24103391-8	2013	Muscimol (GABA(A) agonist) microinjection into the supraoptic nuclei in hypertensive rats increased blood pressure, which was prevented by previous intravenous V1a AVP antagonist injection.	Muscimol	0-8	arginine vasopressin	Rattus norvegicus	164-167
23512936-5	2013	To test this hypothesis, we temporarily inactivated the mPFC with muscimol and tested rats on several olfactory learning tasks.	Muscimol	66-74	complement factor properdin	Mus musculus	56-60
23719807-7	2013	Whereas the GABAA receptor agonist muscimol evoked excitatory, inhibitory, or mixed effects on GnRH neuron firing, the GABAA receptor antagonist picrotoxin resulted in a consistent suppression of firing.	Muscimol	35-43	gonadotropin releasing hormone 1	Homo sapiens	95-99
23438692-7	2013	Pre-training intra-CA1 microinjection of muscimol, a GABA-A receptor agonist, at the dose of 0.01 or 0.02mug/rat, increased the traveled distance or the escape latency and traveled distance to the hidden platform, respectively, indicating a water maze spatial acquisition impairment.	Muscimol	41-49	carbonic anhydrase 1	Rattus norvegicus	19-22
23603244-3	2013	Administration of muscimol (0.1 mug/mouse, intra-CA1) 15 min before training or testing induced impairment of memory retention.	Muscimol	18-26	carbonic anhydrase 1	Mus musculus	49-52
23603244-8	2013	Pre-test intra-CA1 administration of certain doses of yohimbine (0.25 and 0.5 mug/mouse), doses which were ineffective when given alone, improved pre-training muscimol (0.1 mug/mouse)-induced retrieval impairment.	Muscimol	159-167	carbonic anhydrase 1	Mus musculus	15-18
23485993-10	2013	Treating A549 cells with muscimol or with isoflurane (250 microM) reduced the expression of COX-2, an effect that was attenuated by cotreatment with bicuculline.	Muscimol	25-33	prostaglandin-endoperoxide synthase 2	Homo sapiens	92-97
22885233-7	2012	Furthermore, microinjection of muscimol (0.20 nmol) into the CeA increased the number of Fos-like immunoreactive (FLI) neurons in the caudal and intermediate parts of the nucleus of the tractus solitarius (cNTS and iNTS) and the lateral parabrachial nucleus (LPBN).	Muscimol	31-39	carcinoembryonic antigen gene family 4	Rattus norvegicus	61-64
23294161-3	2013	Ligand-receptor docking in an alpha(1)beta(2)gamma(2) GABA(A) receptor homology model along with the obtained SAR indicate that 2a and muscimol share a common binding mode, which deviates from the binding mode of the structurally related antagonist series based on 4-(piperidin-4-yl)-1-hydroxypyrazole (4-PHP, 1).	Muscimol	135-143	sarcosine dehydrogenase	Homo sapiens	110-113
23231965-7	2013	On the other hand, intra-CA1 injection of the higher doses of muscimol (GABA(A) receptor agonist) at 0.25, 0.5 and 1 mug/mouse, not only impaired the spatial change detection on its own, but also affected the reaction to non-spatial novelty.	Muscimol	62-70	carbonic anhydrase 1	Mus musculus	25-28
23246466-7	2013	Intra-CA1 NA microinfusion does not alter retention per se, but reverses the disruptive effect of muscimol given into NTS, PGi or LC.	Muscimol	98-106	carbonic anhydrase 1	Homo sapiens	6-9
22927320-5	2013	On the experimental day, hippocampal neuronal activity was temporarily disrupted during the postprandial period by infusing muscimol (0.5 mug/mul; 1 mul) 5 min after the rats stopped consuming the sucrose solution.	Muscimol	124-132	mitochondrial E3 ubiquitin protein ligase 1	Rattus norvegicus	142-155
23320076-8	2013	Regression analysis revealed that in schizophrenia, the [(3)H]Muscimol binding variance was most related to alpha4 mRNA levels and the [(3)H]Flumazenil binding variance was most related to gamma2S subunit mRNA levels.	Muscimol	62-70	immunoglobulin binding protein 1	Homo sapiens	108-114
23015304-4	2013	Pretreatment with muscimol, a selective GABA(A) receptor agonist, significantly suppressed the ethanol-induced upregulation of IP(3) R-1 protein and its mRNA, which was significantly abolished by bicuculline, a selective GABA(A) receptor antagonist.	Muscimol	18-26	inositol 1,4,5-trisphosphate receptor 1	Mus musculus	127-136
23098796-11	2013	These results demonstrated that GABA(A) receptor activation in the CA1 area of the dorsal hippocampus causes a long-term memory impairment of conditioned context-dependent fear mediated by a long-lasting (>=6 h) muscimol action most likely affecting consolidation processes.	Muscimol	215-223	carbonic anhydrase 1	Mus musculus	67-70
23150429-9	2013	The addition of GABA and the GABA A-type receptor agonist Muscimol inhibited stromal cell proliferation, promoted apoptosis, and arrested cells in S-phase, followed by decreased expression of cyclin D3.	Muscimol	58-66	cyclin D3	Mus musculus	192-201
23320076-0	2013	Increases in [3H]muscimol and [3H]flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to alpha4 and gamma2S mRNA levels respectively.	Muscimol	17-25	immunoglobulin binding protein 1	Homo sapiens	122-128
22909986-3	2012	The results showed that pre-training intra-MS/CA1 administration of nonselective muscarinic Ach antagonist, scopolamine (0.5, 1 and 2 mug/rat) and GABA(A) receptor agonist, muscimol (0.01 and 0.02 mug/rat) impaired, while acetylcholinesterase inhibitor, physostigmine (0.5 and 1 mug/rat) and GABA(A) receptor antagonist, bicuculline (0.25 mug/rat) improved memory acquisition.	Muscimol	173-181	carbonic anhydrase 1	Rattus norvegicus	46-49
22909986-3	2012	The results showed that pre-training intra-MS/CA1 administration of nonselective muscarinic Ach antagonist, scopolamine (0.5, 1 and 2 mug/rat) and GABA(A) receptor agonist, muscimol (0.01 and 0.02 mug/rat) impaired, while acetylcholinesterase inhibitor, physostigmine (0.5 and 1 mug/rat) and GABA(A) receptor antagonist, bicuculline (0.25 mug/rat) improved memory acquisition.	Muscimol	173-181	acetylcholinesterase	Rattus norvegicus	222-242
22909986-4	2012	Moreover, intra-CA1/MS administration of a subthreshold dose of muscimol or bicuculline increased and reversed the impairment induced by scopolamine in MS/CA1 respectively (cross injection).	Muscimol	64-72	carbonic anhydrase 1	Rattus norvegicus	16-19
22909986-4	2012	Moreover, intra-CA1/MS administration of a subthreshold dose of muscimol or bicuculline increased and reversed the impairment induced by scopolamine in MS/CA1 respectively (cross injection).	Muscimol	64-72	carbonic anhydrase 1	Rattus norvegicus	155-158
22909986-5	2012	Also, the result revealed that, intra-CA1/MS administration subthreshold dose of muscimol reduced improvement of memory induced by physostigmine in the MS/CA1, respectively (cross injection).	Muscimol	81-89	carbonic anhydrase 1	Rattus norvegicus	38-41
22909986-5	2012	Also, the result revealed that, intra-CA1/MS administration subthreshold dose of muscimol reduced improvement of memory induced by physostigmine in the MS/CA1, respectively (cross injection).	Muscimol	81-89	carbonic anhydrase 1	Rattus norvegicus	155-158
22885233-3	2012	Muscimol (0.20, 0.35 or 0.50 nmol, in 0.2mul) that was injected bilaterally into the CeA decreased the 0.3M NaCl and water intake in a dose-dependent manner.	Muscimol	0-8	carcinoembryonic antigen gene family 4	Rattus norvegicus	85-88
22885233-5	2012	The inhibitory effect of muscimol (0.20 nmol) on the sodium and water intake could be blocked by pretreatment with bicuculline intra-CeA microinjection (0.4 nmol).	Muscimol	25-33	carcinoembryonic antigen gene family 4	Rattus norvegicus	133-136
22700823-11	2012	Both GABA and the GABA(A)R agonist muscimol increased intestinal fluid secretion of rats.	Muscimol	35-43	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	18-26
22153973-7	2012	When applied to the EPN muscimol decreased zif268 levels in substantia nigra (-29%), whereas STN infusions did not result in significant zif268 changes in any brain area.	Muscimol	24-32	early growth response 1	Rattus norvegicus	43-49
22855812-7	2012	After injection of muscimol at rostral sites in the dSC, fixation became more stable since microsaccade rate was reduced rather than increased.	Muscimol	19-27	Na channel protein 60E	Drosophila melanogaster	52-55
22266218-7	2012	Muscimol enhanced KNT-127-induced dopamine release in mPFC.	Muscimol	0-8	kinectin 1	Homo sapiens	18-21
22546523-11	2012	Rats treated with muscimol in CA1 explored all the objects equally well, irrespective of place or presentation time.	Muscimol	18-26	carbonic anhydrase 1	Rattus norvegicus	30-33
22215379-8	2012	GABA-A receptor stimulation with muscimol increased the proliferation rate of SC, differentiated BM-MSC and differentiated ASC.	Muscimol	33-41	PYD and CARD domain containing	Homo sapiens	123-126
22410341-6	2012	In all neurons, GABA(A) agonist, muscimol (1 and 10 muM), increased EPSC frequency (284.1+-57% and 278.4+-87% of control, respectively), but the GABA(B) agonist, baclofen (10 muM), decreased EPSC frequency (43+-8% of control).	Muscimol	33-41	latexin	Homo sapiens	175-178
22169949-7	2012	Muscimol, a GABA(A) receptor agonist, and diazepam, an agonist to benzodiazepine-binding site of GABA(A) receptor, blocked retention trial-induced ERK phosphorylation and impaired memory retrieval.	Muscimol	0-8	mitogen-activated protein kinase 1	Mus musculus	147-150
21893164-2	2011	A question that remains is if the activity of facilitatory mechanisms, like angiotensin II, is necessary for sodium and water intake induced by muscimol (GABA(A) receptor agonist) injected into the LPBN.	Muscimol	144-152	angiotensinogen	Rattus norvegicus	76-90
22457508-3	2012	We found that neurons in rostral LS (LSr) that project to LH are Fos-activated in proportion to cocaine CPP, and that inhibition of LSr neurons with local baclofen and muscimol microinjection (0.3/0.03 nmol) blocks expression of Fos in LH orexin cells and cocaine preference.	Muscimol	168-176	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	65-68
22457508-3	2012	We found that neurons in rostral LS (LSr) that project to LH are Fos-activated in proportion to cocaine CPP, and that inhibition of LSr neurons with local baclofen and muscimol microinjection (0.3/0.03 nmol) blocks expression of Fos in LH orexin cells and cocaine preference.	Muscimol	168-176	lipolysis stimulated lipoprotein receptor	Rattus norvegicus	132-135
21169393-7	2011	Intra-NAc shell administration of muscimol (225 ng/side) and picrotoxin (125 ng/side), respectively, decreased and increased measures of reward.	Muscimol	34-42	synuclein alpha	Homo sapiens	6-9
22145864-6	2012	However, coincident activation of GABA(A) receptors with muscimol and mGlu4 with the agonist (2S)-S-2-amino-4-phosphonobutanoic acid , increased glutamate release from [(3) H]glutamate-loaded cerebellar synaptosomes above that observed with muscimol alone.	Muscimol	57-65	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	34-41
22145864-6	2012	However, coincident activation of GABA(A) receptors with muscimol and mGlu4 with the agonist (2S)-S-2-amino-4-phosphonobutanoic acid , increased glutamate release from [(3) H]glutamate-loaded cerebellar synaptosomes above that observed with muscimol alone.	Muscimol	241-249	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	34-41
22808090-7	2012	Unilateral administration of either baclofen or muscimol (220 pmol) induced similar patterns of c-fos immunoreactivity in several hypothalamic sites but differed in its induction in the central nucleus of the amygdala.	Muscimol	48-56	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	96-101
21982918-11	2011	The stress response was abolished following 8-OH-DPAT or muscimol microinjection suggesting the cardiovascular responses to stress are mediated by the NRP and likely involve the 5HT(1A) receptor.	Muscimol	57-65	Nrp	Rattus norvegicus	151-154
21700270-6	2011	Therefore, the results suggest that deactivation of LPBN inhibitory mechanisms by muscimol injections into the LPBN is facilitated by endogenous angiotensin II acting on AT(1) receptors in the LPBN, which drives rats to ingest large amounts of hypertonic NaCl.	Muscimol	82-90	angiotensinogen	Rattus norvegicus	145-159
21820173-3	2011	Activation of both GABA-A and GABA-B receptors (GABAAR and GABABR) with the specific agonists muscimol and baclofen, respectively induces [Ca2+]i transients that could be blocked by the specific antagonists bicuculline and CGP55845 and were dependent on extracellular Ca2+.	Muscimol	94-102	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	19-25
21925239-4	2011	Post-training intra-CA1 administration of a GABA-A receptor agonist, muscimol (0.01-0.02 mug/rat) dose-dependently impaired memory retrieval.	Muscimol	69-77	carbonic anhydrase 1	Rattus norvegicus	20-23
21925239-9	2011	Furthermore, the amnesic effect of intra-VTA administration of muscimol was significantly decreased by intra-CA1 administration of sulpiride (0.5 and 1 mug/rat, intra-CA1), but not SCH23390.	Muscimol	63-71	carbonic anhydrase 1	Rattus norvegicus	109-112
21925239-9	2011	Furthermore, the amnesic effect of intra-VTA administration of muscimol was significantly decreased by intra-CA1 administration of sulpiride (0.5 and 1 mug/rat, intra-CA1), but not SCH23390.	Muscimol	63-71	carbonic anhydrase 1	Rattus norvegicus	167-170
21409522-9	2011	BDNF increased the percentage of differentiated cells expressing Tuj-1 sensitive to KCl or AMPA and reduced the population of cells responding to muscimol.	Muscimol	146-154	brain derived neurotrophic factor	Mus musculus	0-4
21596094-5	2011	Systemic injections of the orexin-1 receptor antagonist SB-334867 reduced temperature and cardiovascular responses produced by microinjections of muscimol, but had no effect on either response produced by PgE2.	Muscimol	146-154	hypocretin neuropeptide precursor	Homo sapiens	27-33
21557951-1	2011	AIMS: In the present study, the effects of bilateral intra-dorsal hippocampal (intra-CA1) injections of cholinergic agents on muscimol state-dependent memory were examined in mice.	Muscimol	126-134	carbonic anhydrase 1	Mus musculus	85-88
21557951-3	2011	KEY FINDINGS: Pre-training intra-CA1 administration of a GABA-A receptor agonist, muscimol (0.05 and 0.1 mug/mouse) dose dependently induced impairment of memory retention.	Muscimol	82-90	carbonic anhydrase 1	Mus musculus	33-36
21557951-4	2011	Pre-test injection of muscimol (0.05 and 0.1 mug/mouse, intra-CA1) induced state-dependent retrieval of the memory acquired under pre-training muscimol (0.1 mug/mouse, intra-CA1) influence.	Muscimol	22-30	carbonic anhydrase 1	Mus musculus	62-65
21557951-4	2011	Pre-test injection of muscimol (0.05 and 0.1 mug/mouse, intra-CA1) induced state-dependent retrieval of the memory acquired under pre-training muscimol (0.1 mug/mouse, intra-CA1) influence.	Muscimol	22-30	carbonic anhydrase 1	Mus musculus	174-177
21557951-4	2011	Pre-test injection of muscimol (0.05 and 0.1 mug/mouse, intra-CA1) induced state-dependent retrieval of the memory acquired under pre-training muscimol (0.1 mug/mouse, intra-CA1) influence.	Muscimol	143-151	carbonic anhydrase 1	Mus musculus	62-65
21557951-5	2011	Pre-test intra-CA1 injection of an acetylcholinesterase inhibitor, physostigmine (0.5 and 1 mug/mouse, intra-CA1) reversed the memory impairment induced by pre-training administration of muscimol (0.1 mug/mouse, intra-CA1).	Muscimol	187-195	carbonic anhydrase 1	Mus musculus	15-18
21557951-5	2011	Pre-test intra-CA1 injection of an acetylcholinesterase inhibitor, physostigmine (0.5 and 1 mug/mouse, intra-CA1) reversed the memory impairment induced by pre-training administration of muscimol (0.1 mug/mouse, intra-CA1).	Muscimol	187-195	carbonic anhydrase 1	Mus musculus	109-112
21557951-5	2011	Pre-test intra-CA1 injection of an acetylcholinesterase inhibitor, physostigmine (0.5 and 1 mug/mouse, intra-CA1) reversed the memory impairment induced by pre-training administration of muscimol (0.1 mug/mouse, intra-CA1).	Muscimol	187-195	carbonic anhydrase 1	Mus musculus	109-112
21557951-10	2011	SIGNIFICANCE: The results suggest that muscarinic cholinergic mechanism of the CA1 may influence muscimol state-dependent memory.	Muscimol	97-105	carbonic anhydrase 1	Mus musculus	79-82
21459678-0	2011	Modulation of conditioned fear, fear-conditioned analgesia, and brain regional c-Fos expression following administration of muscimol into the rat basolateral amygdala.	Muscimol	124-132	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	79-84
21459678-2	2011	In this study, we investigated the effects of intra-BLA administration of the GABA(A) receptor agonist muscimol on the expression of conditioned-fear, formalin-evoked nociception, and fear-conditioned analgesia in rats, and the associated alterations in brain regional expression of the immediate early gene product and marker of neuronal activity, c-Fos.	Muscimol	103-111	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	349-354
21459678-5	2011	The suppression of fear behavior by intra-BLA muscimol was associated with increased c-Fos expression in the central nucleus of the amygdala (CeA) and throughout the periaqueductal grey (PAG).	Muscimol	46-54	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	85-90
21459678-5	2011	The suppression of fear behavior by intra-BLA muscimol was associated with increased c-Fos expression in the central nucleus of the amygdala (CeA) and throughout the periaqueductal grey (PAG).	Muscimol	46-54	carcinoembryonic antigen gene family 4	Rattus norvegicus	142-145
21459678-6	2011	These intra-BLA muscimol-induced increases in c-Fos expression were abolished in rats receiving intraplantar formalin injection.	Muscimol	16-24	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	46-51
21044903-6	2011	In addition, pretreatment with a blocker of the Na(+), K(+), 2Cl- co-transporter type 1 (NKCC-1), bumetanide, prevented the muscimol-induced inhibition of eEPSCs.	Muscimol	124-132	solute carrier family 12 member 2	Rattus norvegicus	48-87
21412279-6	2011	To determine the functional implications of the changes in the expression of GABA(A)R-alpha1 subunits, we infused muscimol, a GABA R agonist, into the contralesional cortex for a week after the injury.	Muscimol	114-122	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	Mus musculus	77-92
21186269-10	2011	Inhibition of ARCN by microinjections of muscimol (1 mM) attenuated the pressor and tachycardic responses to intravenously administered ANG-(1-12) and ANG II (300 pmol/kg each).	Muscimol	41-49	angiogenin	Rattus norvegicus	136-139
21186269-10	2011	Inhibition of ARCN by microinjections of muscimol (1 mM) attenuated the pressor and tachycardic responses to intravenously administered ANG-(1-12) and ANG II (300 pmol/kg each).	Muscimol	41-49	angiotensinogen	Rattus norvegicus	151-157
21044903-6	2011	In addition, pretreatment with a blocker of the Na(+), K(+), 2Cl- co-transporter type 1 (NKCC-1), bumetanide, prevented the muscimol-induced inhibition of eEPSCs.	Muscimol	124-132	solute carrier family 12 member 2	Rattus norvegicus	89-95
24363691-6	2011	Pre-test intra-CA1 injection of muscimol (0.05 mug/mouse) by itself reversed the decrease of step-down latency induced by post-training lithium (10 mg/kg).	Muscimol	32-40	carbonic anhydrase 1	Mus musculus	15-18
21532213-7	2011	Muscimol infusion in the AV3V, but not in the cerebral ventricle, inhibited the responses of plasma AVP and glucose, despite having no effect in a sham hemorrhagic state.	Muscimol	0-8	arginine vasopressin	Rattus norvegicus	100-103
21532213-8	2011	The inhibition of the AVP response by the muscimol infusion was also verified in rats given a combined stimulus of bleeding plus an osmotic load.	Muscimol	42-50	arginine vasopressin	Rattus norvegicus	22-25
24363691-7	2011	Pre-test intra-CA1 injection of muscimol (0.03 and 0.05 mug/mouse) also disrupted state-dependent learning induced by lithium (10 mg/kg).	Muscimol	32-40	carbonic anhydrase 1	Mus musculus	15-18
20142297-3	2011	[(3)H]-Muscimol binding assays revealed significant reduction in the density of GABA(A) receptors in CA2 (30%) and DG (28%) of the hippocampus, thalamus (40%), cingulate (28%) and motor cortex (35%) of CB(1)(-/-) mice.	Muscimol	7-15	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	80-87
20142297-3	2011	[(3)H]-Muscimol binding assays revealed significant reduction in the density of GABA(A) receptors in CA2 (30%) and DG (28%) of the hippocampus, thalamus (40%), cingulate (28%) and motor cortex (35%) of CB(1)(-/-) mice.	Muscimol	7-15	carbonic anhydrase 2	Mus musculus	101-104
20331983-6	2010	The present results show that water and 0.3M NaCl intake induced by the blockade of LPBN neurons with muscimol depends on the integrity of the CeA, suggesting that facilitatory mechanisms present in the CeA are essential for water and hypertonic NaCl intake that arises after the blockade of the inhibitory mechanisms of the LPBN with muscimol.	Muscimol	335-343	carcinoembryonic antigen gene family 4	Rattus norvegicus	203-206
21123565-4	2010	In both males and females, the mPFC was bilaterally inactivated with GABA agonist muscimol before the stressor.	Muscimol	82-90	complement factor properdin	Mus musculus	31-35
20888891-8	2010	Following a low dose of SP infused into the RVM, intrathecal muscimol (GABA(A) agonist) increased SP-induced thermal hyperalgesia, phosphorylated NKCC1 protein expression, and NMDA NR1 subunit phosphorylation in the spinal cord.	Muscimol	61-69	tachykinin precursor 1	Homo sapiens	24-26
20888891-8	2010	Following a low dose of SP infused into the RVM, intrathecal muscimol (GABA(A) agonist) increased SP-induced thermal hyperalgesia, phosphorylated NKCC1 protein expression, and NMDA NR1 subunit phosphorylation in the spinal cord.	Muscimol	61-69	tachykinin precursor 1	Homo sapiens	98-100
20888891-8	2010	Following a low dose of SP infused into the RVM, intrathecal muscimol (GABA(A) agonist) increased SP-induced thermal hyperalgesia, phosphorylated NKCC1 protein expression, and NMDA NR1 subunit phosphorylation in the spinal cord.	Muscimol	61-69	solute carrier family 12 member 2	Homo sapiens	146-151
20888891-8	2010	Following a low dose of SP infused into the RVM, intrathecal muscimol (GABA(A) agonist) increased SP-induced thermal hyperalgesia, phosphorylated NKCC1 protein expression, and NMDA NR1 subunit phosphorylation in the spinal cord.	Muscimol	61-69	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	181-184
20403442-7	2010	Mutants with defective lysosome function (cup-5) show elevated GABA(A) receptor levels at synapses prior to muscimol exposure.	Muscimol	108-116	PKD_channel domain-containing protein	Caenorhabditis elegans	42-47
20331983-1	2010	The blockade of the lateral parabrachial nucleus (LPBN) with the GABAergic receptor agonist muscimol induces strong hypertonic NaCl intake in satiated and normovolemic rats, whereas lesions of the central nucleus of the amygdala (CeA) reduce sodium intake induced by different protocols.	Muscimol	92-100	carcinoembryonic antigen gene family 4	Rattus norvegicus	230-233
20377624-10	2010	IGL microinjection of the GABA agonist, muscimol, suppressed SCN NPY release.	Muscimol	40-48	neuropeptide Y	Homo sapiens	65-68
20331983-5	2010	Bilateral lesions of the CeA (3days) abolished 0.3M NaCl intake (0.1+/-0.1ml/4h) and water intake (0.1+/-0.1ml/4h) induced by bilateral injections of muscimol into the LPBN in satiated rats.	Muscimol	150-158	carcinoembryonic antigen gene family 4	Rattus norvegicus	25-28
20331983-6	2010	The present results show that water and 0.3M NaCl intake induced by the blockade of LPBN neurons with muscimol depends on the integrity of the CeA, suggesting that facilitatory mechanisms present in the CeA are essential for water and hypertonic NaCl intake that arises after the blockade of the inhibitory mechanisms of the LPBN with muscimol.	Muscimol	102-110	carcinoembryonic antigen gene family 4	Rattus norvegicus	203-206
20331983-6	2010	The present results show that water and 0.3M NaCl intake induced by the blockade of LPBN neurons with muscimol depends on the integrity of the CeA, suggesting that facilitatory mechanisms present in the CeA are essential for water and hypertonic NaCl intake that arises after the blockade of the inhibitory mechanisms of the LPBN with muscimol.	Muscimol	335-343	carcinoembryonic antigen gene family 4	Rattus norvegicus	143-146
20364882-0	2010	Suppression of third ventricular NPY-elicited feeding following medullary reticular formation infusions of muscimol.	Muscimol	107-115	neuropeptide Y	Rattus norvegicus	33-36
20364882-7	2010	NPY 3-36-induced food intake was suppressed (1.7 g +/- 0.48) by simultaneous infusions of muscimol (0.6 mM/100 nl) into the IRt/PCRt (p < .01).	Muscimol	90-98	neuropeptide Y	Rattus norvegicus	0-3
20333300-5	2010	In a second series of experiments we found that the GABA(A) receptor agonist muscimol could rescue the cleft palate phenotype in Gad1 and Viaat mutant embryos.	Muscimol	77-85	glutamate decarboxylase 1	Mus musculus	129-133
20333300-5	2010	In a second series of experiments we found that the GABA(A) receptor agonist muscimol could rescue the cleft palate phenotype in Gad1 and Viaat mutant embryos.	Muscimol	77-85	solute carrier family 32 (GABA vesicular transporter), member 1	Mus musculus	138-143
19694794-5	2010	RESULTS: Coadministration of muscimol and baclofen exerted neuroprotection against neuron death induced by KA; inhibited the increased assembly of the GluR6-PSD-95-MLK3 module induced by KA; and suppressed the activation of MLK3, MKK7, and JNK3.	Muscimol	29-37	glutamate ionotropic receptor kainate type subunit 2	Rattus norvegicus	151-156
19694794-5	2010	RESULTS: Coadministration of muscimol and baclofen exerted neuroprotection against neuron death induced by KA; inhibited the increased assembly of the GluR6-PSD-95-MLK3 module induced by KA; and suppressed the activation of MLK3, MKK7, and JNK3.	Muscimol	29-37	discs large MAGUK scaffold protein 4	Rattus norvegicus	157-163
19694794-5	2010	RESULTS: Coadministration of muscimol and baclofen exerted neuroprotection against neuron death induced by KA; inhibited the increased assembly of the GluR6-PSD-95-MLK3 module induced by KA; and suppressed the activation of MLK3, MKK7, and JNK3.	Muscimol	29-37	mitogen-activated protein kinase kinase kinase 11	Rattus norvegicus	164-168
19694794-5	2010	RESULTS: Coadministration of muscimol and baclofen exerted neuroprotection against neuron death induced by KA; inhibited the increased assembly of the GluR6-PSD-95-MLK3 module induced by KA; and suppressed the activation of MLK3, MKK7, and JNK3.	Muscimol	29-37	mitogen-activated protein kinase kinase kinase 11	Rattus norvegicus	224-228
19694794-5	2010	RESULTS: Coadministration of muscimol and baclofen exerted neuroprotection against neuron death induced by KA; inhibited the increased assembly of the GluR6-PSD-95-MLK3 module induced by KA; and suppressed the activation of MLK3, MKK7, and JNK3.	Muscimol	29-37	mitogen activated protein kinase kinase 7	Rattus norvegicus	230-234
19694794-5	2010	RESULTS: Coadministration of muscimol and baclofen exerted neuroprotection against neuron death induced by KA; inhibited the increased assembly of the GluR6-PSD-95-MLK3 module induced by KA; and suppressed the activation of MLK3, MKK7, and JNK3.	Muscimol	29-37	mitogen activated protein kinase 10	Rattus norvegicus	240-244
19959723-4	2010	Muscimol (a GABA(A)R agonist) induced single Ca(2+) transients involving both VGCC-mediated Ca(2+) influx and intracellular stores, while baclofen (a GABA(B)R agonist) evoked Ca(2+) transients followed by intercellular Ca(2+) waves and oscillations that were resistant to antagonists and entirely dependent on Ca(2+) release from intracellular stores.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	12-20
20032968-1	2010	Muscimol has been regarded as a universal agonist for all gamma-aminobutyric acid type A receptor (GABA(A)-R) subtypes.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	58-97
20032968-1	2010	Muscimol has been regarded as a universal agonist for all gamma-aminobutyric acid type A receptor (GABA(A)-R) subtypes.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	99-108
20032968-2	2010	However, brain regional distribution of muscimol"s high-affinity binding sites greatly differs from those of other binding sites of the GABA(A)-R.	Muscimol	40-48	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	136-145
19786036-9	2010	SP did not alter the paired-pulse ratio, but reduced the amplitudes of GABA(A) agonist muscimol-induced outward currents and miniature IPSCs in cholinergic interneurons, suggesting SP exerts its effects primarily at the post-synaptic site.	Muscimol	87-95	tachykinin 1	Mus musculus	0-2
20297739-9	2010	The muscimol-induced current in the hippocampal CA1 pyramidal neurons and hippocampal expression of the 67-kDa isoform of glutamic acid decarboxylase significantly decreased in the Usp46 mutant mice compared to control mice.	Muscimol	4-12	carbonic anhydrase 1	Mus musculus	48-51
20297739-9	2010	The muscimol-induced current in the hippocampal CA1 pyramidal neurons and hippocampal expression of the 67-kDa isoform of glutamic acid decarboxylase significantly decreased in the Usp46 mutant mice compared to control mice.	Muscimol	4-12	ubiquitin specific peptidase 46	Mus musculus	181-186
19786036-9	2010	SP did not alter the paired-pulse ratio, but reduced the amplitudes of GABA(A) agonist muscimol-induced outward currents and miniature IPSCs in cholinergic interneurons, suggesting SP exerts its effects primarily at the post-synaptic site.	Muscimol	87-95	tachykinin 1	Mus musculus	181-183
19864584-5	2009	Unexpectedly, treatment with muscimol, a GABA(A) receptor agonist, selectively stimulated elongation of axons but not of dendrites, and the CaMKK-CaMKIalpha cascade critically mediated this axonogenic effect.	Muscimol	29-37	calcium/calmodulin dependent protein kinase kinase 2	Homo sapiens	140-145
19723567-9	2009	Meanwhile, naloxone as well as muscimol and baclofen significantly attenuated the increases of the POMC gene expression induced by a single morphine administration.	Muscimol	31-39	pro-opiomelanocortin-alpha	Mus musculus	99-103
19665526-9	2009	By contrast, when muscimol was infused in dorsal agranular insular cortex (AId)-a region that is strongly interconnected with dorsomedial prefrontal regions-there was no effect on delayed spatial alternation performance.	Muscimol	18-26	activation-induced cytidine deaminase	Rattus norvegicus	75-78
19923355-4	2010	After injection of vehicle into the dorsomedial hypothalamus, injection of muscimol into the medial preoptic area elicited marked increases in heart rate, arterial pressure, body temperature, plasma ACTH, and locomotor activity and also increased c-Fos expression in the hypothalamic paraventricular nucleus, a region known to control the release of ACTH from the adenohypophysis.	Muscimol	75-83	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	247-252
19906878-6	2010	The resulting receptors were activated by insect GABA-receptor agonists muscimol and CACA and blocked by antagonists fipronil, dieldrin, and picrotoxin, but not bicuculline, displaying a typical RDL-like pharmacology.	Muscimol	72-80	gamma-aminobutyric acid receptor subunit beta	Apis mellifera	195-198
19864584-5	2009	Unexpectedly, treatment with muscimol, a GABA(A) receptor agonist, selectively stimulated elongation of axons but not of dendrites, and the CaMKK-CaMKIalpha cascade critically mediated this axonogenic effect.	Muscimol	29-37	calcium/calmodulin dependent protein kinase I	Homo sapiens	146-156
19587111-6	2009	The facilitating effect of endogenous ANG II on the GABAergic input to the MnPO was not attributed to a change in GABA release probability and was mimicked by exogenous ANG II, which potentiated the amplitude of the muscimol-activated GABA(A)/Cl(-) current by 53.1 +/- 11.4%.	Muscimol	216-224	angiotensinogen	Rattus norvegicus	38-44
19587111-6	2009	The facilitating effect of endogenous ANG II on the GABAergic input to the MnPO was not attributed to a change in GABA release probability and was mimicked by exogenous ANG II, which potentiated the amplitude of the muscimol-activated GABA(A)/Cl(-) current by 53.1 +/- 11.4%.	Muscimol	216-224	angiotensinogen	Rattus norvegicus	169-175
19415297-1	2009	This study was designed to examine the effects of intracerebroventricular (ICV) injection of bicuculline (GABA(A) receptor antagonist) and muscimol (GABA(A) receptor agonist) on glutamate-induced eating response in 24-h food-deprived (FD24) broiler cockerels.	Muscimol	139-147	gamma-aminobutyric acid type A receptor gamma3 subunit	Gallus gallus	149-165
19447274-3	2009	Pre-training intra-CA1 administration of a GABAA receptor agonist, muscimol (0.025, 0.05, 0.1 and 0.2 microg/mouse) dose dependently induced impairment of memory retention.	Muscimol	67-75	carbonic anhydrase 1	Mus musculus	19-22
19447274-4	2009	Pre-test injection of muscimol (0.05, 0.1 and 0.2 microg/mouse, intra-CA1) induced state-dependent retrieval of the memory acquired under pre-training muscimol (0.1 microg/mouse, intra-CA1) influence.	Muscimol	22-30	carbonic anhydrase 1	Mus musculus	70-73
19447274-4	2009	Pre-test injection of muscimol (0.05, 0.1 and 0.2 microg/mouse, intra-CA1) induced state-dependent retrieval of the memory acquired under pre-training muscimol (0.1 microg/mouse, intra-CA1) influence.	Muscimol	22-30	carbonic anhydrase 1	Mus musculus	185-188
19447274-4	2009	Pre-test injection of muscimol (0.05, 0.1 and 0.2 microg/mouse, intra-CA1) induced state-dependent retrieval of the memory acquired under pre-training muscimol (0.1 microg/mouse, intra-CA1) influence.	Muscimol	151-159	carbonic anhydrase 1	Mus musculus	70-73
19447274-5	2009	Pre-test injection of morphine (0.5 and 1 mg/kg, s.c.) 30 min before the administration of muscimol (0.1 microg/mouse, intra-CA1) dose dependently inhibited muscimol state-dependent memory.	Muscimol	91-99	carbonic anhydrase 1	Mus musculus	125-128
19447274-6	2009	Pre-test intra-CA1 injection of naloxone (0.1 and 0.2 microg/mouse, intra-CA1) improved pre-training muscimol (0.1 microg/mouse)-induced retrieval impairment.	Muscimol	101-109	carbonic anhydrase 1	Mus musculus	15-18
19447274-6	2009	Pre-test intra-CA1 injection of naloxone (0.1 and 0.2 microg/mouse, intra-CA1) improved pre-training muscimol (0.1 microg/mouse)-induced retrieval impairment.	Muscimol	101-109	carbonic anhydrase 1	Mus musculus	74-77
19458221-9	2009	Conversely, inactivation of CeA by muscimol microinjection (0.25 microg) suppressed approach, nibbles, and sniffs of the prepotent CS.	Muscimol	35-43	carcinoembryonic antigen gene family 4	Rattus norvegicus	28-31
19406109-6	2009	Moreover, the GABA receptor agonist muscimol could attenuate the JNK3 phosphorylation.	Muscimol	36-44	GABA type A receptor-associated protein	Homo sapiens	14-27
19406109-6	2009	Moreover, the GABA receptor agonist muscimol could attenuate the JNK3 phosphorylation.	Muscimol	36-44	mitogen-activated protein kinase 10	Homo sapiens	65-69
19465912-7	2009	The muscimol-induced current in the hippocampal CA1 pyramidal neurons and hippocampal expression of the 67-kDa isoform of glutamic acid decarboxylase were significantly decreased in the Usp46 mutant mice compared to control mice.	Muscimol	4-12	carbonic anhydrase 1	Mus musculus	48-51
19465912-7	2009	The muscimol-induced current in the hippocampal CA1 pyramidal neurons and hippocampal expression of the 67-kDa isoform of glutamic acid decarboxylase were significantly decreased in the Usp46 mutant mice compared to control mice.	Muscimol	4-12	ubiquitin specific peptidase 46	Mus musculus	186-191
19308943-9	2009	The GABA-A receptor agonist, muscimol ameliorated the Hcy-mediated MMP-9 activation.	Muscimol	29-37	matrix metallopeptidase 9	Homo sapiens	67-72
19308943-11	2009	Treatment of the endothelial cell with muscimol restored the levels of TIMP-4 to the levels in control group.	Muscimol	39-47	TIMP metallopeptidase inhibitor 4	Homo sapiens	71-77
19308943-13	2009	Furthermore muscimol attenuated Hcy-induced MMP-9 via ERK signaling pathway.	Muscimol	12-20	matrix metallopeptidase 9	Homo sapiens	44-49
19308943-13	2009	Furthermore muscimol attenuated Hcy-induced MMP-9 via ERK signaling pathway.	Muscimol	12-20	mitogen-activated protein kinase 1	Homo sapiens	54-57
19458221-10	2009	Confirming modulation of incentive salience, unconditioned food intake was similarly increased by DAMGO microinjection and decreased by muscimol in CeA.	Muscimol	136-144	carcinoembryonic antigen gene family 4	Rattus norvegicus	148-151
19377819-3	2009	Meanwhile, application of the GABA(A) receptor agonist muscimol (MUS) potentiated the correlated activities while decreasing the firing rates.	Muscimol	55-63	gamma-aminobutyric acid type A receptor gamma3 subunit	Gallus gallus	30-46
19416636-8	2009	Raclopride or bicuculline alone in A11 had no effects, whereas muscimol (a GABA(A) receptor agonist) alone in A11 suppressed hypersensitivity.	Muscimol	63-71	selectin L	Rattus norvegicus	110-113
19429351-9	2009	Muscimol, a GABA(A) agonist, exhibited antinociceptive effects in the formalin test and NMDA-induced behaviors in a manner similar to that of ARE.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	12-19
18512761-5	2008	Coapplication of muscimol with baclofen not only enhanced nNOS (Ser847) phosphorylation but also increased the interaction of nNOS with PSD95 at 6 hr and 1 day of reperfusion.	Muscimol	17-25	nitric oxide synthase 1	Homo sapiens	58-62
18434046-1	2009	The effect of prolonged, intermittent infusion of GABA(A) receptor agonist (muscimol) or GABA(A) receptor antagonist (bicuculline) into the third cerebral ventricle on the expression of GnRH gene and GnRH-R gene in the hypothalamus and GnRH-R gene in the anterior pituitary gland was examined in follicular-phase ewes by real-time PCR.	Muscimol	76-84	gonadotropin releasing hormone 1	Homo sapiens	186-190
18434046-1	2009	The effect of prolonged, intermittent infusion of GABA(A) receptor agonist (muscimol) or GABA(A) receptor antagonist (bicuculline) into the third cerebral ventricle on the expression of GnRH gene and GnRH-R gene in the hypothalamus and GnRH-R gene in the anterior pituitary gland was examined in follicular-phase ewes by real-time PCR.	Muscimol	76-84	gonadotropin releasing hormone receptor	Homo sapiens	200-206
18434046-4	2009	The decrease or increase of GnRH-R mRNA in the anterior pituitary gland and LH secretion in the muscimol- or bicuculline-treated ewes, respectively, is probably a consequence of parallel changes in the release of GnRH from the hypothalamus activating GnRH-R gene expression.	Muscimol	96-104	gonadotropin releasing hormone receptor	Homo sapiens	28-34
18434046-4	2009	The decrease or increase of GnRH-R mRNA in the anterior pituitary gland and LH secretion in the muscimol- or bicuculline-treated ewes, respectively, is probably a consequence of parallel changes in the release of GnRH from the hypothalamus activating GnRH-R gene expression.	Muscimol	96-104	gonadotropin releasing hormone 1	Homo sapiens	28-32
18434046-4	2009	The decrease or increase of GnRH-R mRNA in the anterior pituitary gland and LH secretion in the muscimol- or bicuculline-treated ewes, respectively, is probably a consequence of parallel changes in the release of GnRH from the hypothalamus activating GnRH-R gene expression.	Muscimol	96-104	gonadotropin releasing hormone receptor	Homo sapiens	251-257
19007810-8	2009	Gd3+ inhibited the muscimol-induced outward current in a concentration-dependent and reversible manner.	Muscimol	19-27	GRDX	Homo sapiens	0-3
19007810-9	2009	Gd3+ inhibited the maximum muscimol response but had no effect on the half-maximum concentration.	Muscimol	27-35	GRDX	Homo sapiens	0-3
18678878-8	2008	GABA(A) receptor agonist muscimol could attenuate Src activation and interactions among NR2A, PSD-95 and Src, resulting the suppression of NMDA receptor tyrosine phosphorylation.	Muscimol	25-33	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	50-53
18678878-8	2008	GABA(A) receptor agonist muscimol could attenuate Src activation and interactions among NR2A, PSD-95 and Src, resulting the suppression of NMDA receptor tyrosine phosphorylation.	Muscimol	25-33	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	88-92
18678878-8	2008	GABA(A) receptor agonist muscimol could attenuate Src activation and interactions among NR2A, PSD-95 and Src, resulting the suppression of NMDA receptor tyrosine phosphorylation.	Muscimol	25-33	discs large MAGUK scaffold protein 4	Homo sapiens	94-100
18678878-8	2008	GABA(A) receptor agonist muscimol could attenuate Src activation and interactions among NR2A, PSD-95 and Src, resulting the suppression of NMDA receptor tyrosine phosphorylation.	Muscimol	25-33	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	105-108
18722360-5	2008	We examined the effects of inactivation of MnPN neurons by locally microinjecting 0.2 microl of 1 mM or 10 mM solutions of a GABA(A) receptor agonist, muscimol, into the MnPN on Fos expression (Fos-IR) in the PF-LHA neurons including HCRT neurons and 5-HT neurons in the DRN in anesthetized rats.	Muscimol	151-159	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	178-181
18722360-6	2008	Compared to artificial cerebrospinal fluid control, microinjection of muscimol into the MnPN resulted in significantly higher percentages of HCRT and non-HCRT neurons in the PF-LHA and 5-HT neurons in the DRN that exhibited Fos-IR.	Muscimol	70-78	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	224-227
19150477-13	2009	The results obtained showed that intra-CeA injections of muscimol (1 nmol) and DAMGO (0.5 and 1 nmol) significantly inhibited this response.	Muscimol	57-65	carcinoembryonic antigen gene family 4	Rattus norvegicus	39-42
19219304-4	2009	Muscimol reduced the effects of BVE on sodium excretion (isotonic: 2.4 +/- 0.3 vs vehicle: 4.8 +/- 0.2 and hypertonic: 4.0 +/- 0.7 vs vehicle: 8.7 +/- 0.6 microEq.100 g-1.40 min-1); urinary volume after hypertonic BVE (83.8 +/- 10 vs vehicle: 255.6 +/- 16.5 microL.100 g-1.40 min-1); plasma OT levels (isotonic: 15.3 +/- 0.6 vs vehicle: 19.3 +/- 1 and hypertonic: 26.5 +/- 2.6 vs vehicle: 48 +/- 3 pg/mL), and ANP levels (isotonic: 97 +/- 12.8 vs vehicle: 258.3 +/- 28.1 and hypertonic: 160 +/- 14.6 vs vehicle: 318 +/- 16.3 pg/mL).	Muscimol	0-8	natriuretic peptide A	Rattus norvegicus	410-413
18670763-0	2008	Self-administration of the GABAA agonist muscimol into the medial septum: dependence on dopaminergic mechanisms.	Muscimol	41-49	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	27-32
18670763-2	2008	OBJECTIVES: We used intracranial self-administration to determine whether the GABAA agonist muscimol or antagonist bicuculline might have rewarding effects when infused into the MSDB.	Muscimol	92-100	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	78-83
18512761-5	2008	Coapplication of muscimol with baclofen not only enhanced nNOS (Ser847) phosphorylation but also increased the interaction of nNOS with PSD95 at 6 hr and 1 day of reperfusion.	Muscimol	17-25	nitric oxide synthase 1	Homo sapiens	126-130
18512761-5	2008	Coapplication of muscimol with baclofen not only enhanced nNOS (Ser847) phosphorylation but also increased the interaction of nNOS with PSD95 at 6 hr and 1 day of reperfusion.	Muscimol	17-25	discs large MAGUK scaffold protein 4	Homo sapiens	136-141
18410948-7	2008	Moreover, MKK4/MKK7-JNK signaling activation was inhibited during ischemia/reperfusion (I/R) by co-treatment of muscimol with baclofen.	Muscimol	112-120	mitogen activated protein kinase kinase 4	Rattus norvegicus	10-14
18440993-7	2008	In anaesthetized rats with unilateral lesions of around 70% of the Phox2b(+)TH(-) neurons, acute inhibition of the contralateral intact RTN with muscimol instantly eliminated phrenic nerve discharge (PND) but normal PND could usually be elicited by strong peripheral chemoreceptor stimulation (8/12 rats).	Muscimol	145-153	paired-like homeobox 2b	Rattus norvegicus	67-73
18410948-4	2008	The additive neuroprotection could be obtained in the hippocampal CA1 pyramidal cells prominently when muscimol and baclofen were co-applied.	Muscimol	103-111	carbonic anhydrase 1	Rattus norvegicus	66-69
18621125-7	2008	Furthermore we identified the two GABA-analogues, muscimol and THPO as novel hPAT1 substrates.	Muscimol	50-58	solute carrier family 36 member 1	Homo sapiens	77-82
18621125-8	2008	THPO had an affinity for hPAT1 of 11.3mM, whereas muscimol had one of the highest affinities for hPAT1 (1.7mM) reported.	Muscimol	50-58	solute carrier family 36 member 1	Homo sapiens	97-102
18621125-10	2008	Furthermore, the affinity of THPO and muscimol underlines the possible importance of hPAT1 as a transporter for heterocyclic compounds consisting of a 3-isoxazolol moiety, which has been shown to function as a carboxylic acid bioisostere for substrates of the GABA receptor and transport systems.	Muscimol	38-46	solute carrier family 36 member 1	Homo sapiens	85-90
18621125-10	2008	Furthermore, the affinity of THPO and muscimol underlines the possible importance of hPAT1 as a transporter for heterocyclic compounds consisting of a 3-isoxazolol moiety, which has been shown to function as a carboxylic acid bioisostere for substrates of the GABA receptor and transport systems.	Muscimol	38-46	GABA type A receptor-associated protein	Homo sapiens	260-273
18478544-3	2008	Sustained exposure to the GABA(A)R agonist muscimol at 100 microM led to significant increases in the size of neurospheres cultured for 6-10 days, with increased proliferative activity and unchanged lactate dehydrogenase release in a manner sensitive to the GABA(A)R antagonist bicuculline.	Muscimol	43-51	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	26-34
18478544-3	2008	Sustained exposure to the GABA(A)R agonist muscimol at 100 microM led to significant increases in the size of neurospheres cultured for 6-10 days, with increased proliferative activity and unchanged lactate dehydrogenase release in a manner sensitive to the GABA(A)R antagonist bicuculline.	Muscimol	43-51	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	258-266
18547546-3	2008	The treatment with muscimol, a gamma amino butyric acid receptor-A (GABA(A)) agonist, mitigates the AD syndrome and vascular dementia.	Muscimol	19-27	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	31-66
18547546-3	2008	The treatment with muscimol, a gamma amino butyric acid receptor-A (GABA(A)) agonist, mitigates the AD syndrome and vascular dementia.	Muscimol	19-27	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	68-75
18410948-7	2008	Moreover, MKK4/MKK7-JNK signaling activation was inhibited during ischemia/reperfusion (I/R) by co-treatment of muscimol with baclofen.	Muscimol	112-120	mitogen activated protein kinase kinase 7	Rattus norvegicus	15-19
18410948-7	2008	Moreover, MKK4/MKK7-JNK signaling activation was inhibited during ischemia/reperfusion (I/R) by co-treatment of muscimol with baclofen.	Muscimol	112-120	mitogen-activated protein kinase 8	Rattus norvegicus	20-23
18055218-4	2008	The atypical behaviour of GABAergic drugs in cultures pretreated with BDNF depended on changes in the anion reversal potential because (i) increases in extracellular Cl(-) concentrations abolished the neurotoxic action of muscimol; (ii) muscimol stimulated (36)Cl(-) efflux after pretreatment with BDNF; and (iii) exposure to BDNF reduced the expression of the neuronal K(+)/Cl(-) co-transporter, KCC2.	Muscimol	222-230	brain derived neurotrophic factor	Mus musculus	70-74
18463175-7	2008	When the mPFC was inactivated by muscimol (GABA(A) receptor agonist) in the normal animals with intact hippocampi, they showed the same severe impairment as seen in the hippocampal lesioned rats only in object-in-place arms.	Muscimol	33-41	complement factor properdin	Mus musculus	9-13
17568395-7	2008	Inactivation of the ACe with muscimol decreased self-administration at the 0.03 and 0.01 mg/kg/infusion unit doses in HR rats, but had no effect on LR rats.	Muscimol	29-37	angiotensin I converting enzyme	Rattus norvegicus	20-23
18076645-9	2008	Bumetanide (20 microM), a NKCC1 antagonist, partially suppressed muscimol-induced excitation in large neurons.	Muscimol	65-73	solute carrier family 12 member 2	Homo sapiens	26-31
18076645-10	2008	Concordant with robust expression of CaV1.2 and CaV1.3 subunits in HH neurons, the L-type calcium channel blocker nifedipine (100 microM) prevented muscimol-induced neuronal excitation.	Muscimol	148-156	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	37-43
18076645-10	2008	Concordant with robust expression of CaV1.2 and CaV1.3 subunits in HH neurons, the L-type calcium channel blocker nifedipine (100 microM) prevented muscimol-induced neuronal excitation.	Muscimol	148-156	calcium voltage-gated channel subunit alpha1 D	Homo sapiens	48-54
18055218-4	2008	The atypical behaviour of GABAergic drugs in cultures pretreated with BDNF depended on changes in the anion reversal potential because (i) increases in extracellular Cl(-) concentrations abolished the neurotoxic action of muscimol; (ii) muscimol stimulated (36)Cl(-) efflux after pretreatment with BDNF; and (iii) exposure to BDNF reduced the expression of the neuronal K(+)/Cl(-) co-transporter, KCC2.	Muscimol	237-245	brain derived neurotrophic factor	Mus musculus	70-74
17916335-6	2007	The increase of P-ERK levels was inhibited by the agonist of GABAA receptor, muscimol, and further increased by the antagonist of the receptor, bicuculline.	Muscimol	77-85	Eph receptor B1	Rattus norvegicus	18-21
18849647-5	2008	The intra-CeA injection of the GABAA receptor agonist muscimol (0.25, 0.5 and 0.75 microg/rat; 1 microl/rat; 0.5 microl/rat in each side) decreased %OAT and %OAE, indicating anxiogenic-like behaviour.	Muscimol	54-62	carcinoembryonic antigen gene family 4	Rattus norvegicus	10-13
18022328-5	2007	Our results indicate that whether in global cerebral ischemia in vivo, or in oxygen glucose deprivation (OGD) in vitro, coapplication of muscimol with baclofen can protect neurons from neuronal death through down-regulating the function of N-methyl-d-aspartic acid (NMDA) receptors via attenuating the tyrosine phosphorylation of NR2A subunit.	Muscimol	137-145	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	330-334
18022328-6	2007	We further elucidate that the phosphorylation level of Src kinase and the interaction among Src, post-synaptic density protein 95 and NR2A were also suppressed by coapplication of muscimol with baclofen.	Muscimol	180-188	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	55-58
18022328-6	2007	We further elucidate that the phosphorylation level of Src kinase and the interaction among Src, post-synaptic density protein 95 and NR2A were also suppressed by coapplication of muscimol with baclofen.	Muscimol	180-188	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	92-95
18022328-6	2007	We further elucidate that the phosphorylation level of Src kinase and the interaction among Src, post-synaptic density protein 95 and NR2A were also suppressed by coapplication of muscimol with baclofen.	Muscimol	180-188	discs large MAGUK scaffold protein 4	Rattus norvegicus	97-129
18022328-6	2007	We further elucidate that the phosphorylation level of Src kinase and the interaction among Src, post-synaptic density protein 95 and NR2A were also suppressed by coapplication of muscimol with baclofen.	Muscimol	180-188	glutamate ionotropic receptor NMDA type subunit 2A	Rattus norvegicus	134-138
17442049-3	2007	Basal level of both hippocampal and cerebellar [(3)H]muscimol binding was lower and sensitivity to the hypothermic effects of diazepam and pentobarbital was increased in CB1-/- mice.	Muscimol	53-61	cannabinoid receptor 1 (brain)	Mus musculus	170-173
17848503-7	2007	Lastly, muscimol infusions into the CEA prevented both the acquisition and the expression of overtrained fear, demonstrating that the effects of CEA lesions are not likely due to the destruction of en passant axons.	Muscimol	8-16	carcinoembryonic antigen gene family 4	Rattus norvegicus	36-39
17848503-7	2007	Lastly, muscimol infusions into the CEA prevented both the acquisition and the expression of overtrained fear, demonstrating that the effects of CEA lesions are not likely due to the destruction of en passant axons.	Muscimol	8-16	carcinoembryonic antigen gene family 4	Rattus norvegicus	145-148
17049168-5	2007	The decrease in MAP evoked by muscimol was accompanied by a significant increase in HR (muscimol 69+/-13 bpm vs. vehicle -33+/-12 bpm, P<0.05), an effect that was completely abolished by beta1 adrenergic receptor blockade.	Muscimol	30-38	adrenoceptor beta 1	Rattus norvegicus	190-215
17353094-0	2007	The effect of a GABAA agonist muscimol on acoustic injury of the mouse cochlea.	Muscimol	30-38	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	16-21
17179652-7	2007	GABA and the GABA-A receptor agonist muscimol, but not the GABA-B receptor agonist baclofen, significantly increased the EGFP-positive/GnRH-positive cell ratio.	Muscimol	37-45	gonadotropin releasing hormone 1	Rattus norvegicus	135-139
17570598-3	2007	dose of muscimol, a selective GABA(A) agonist.	Muscimol	8-16	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	30-37
17551323-6	2007	administration of the GABAA receptor agonist, muscimol (0.025, 0.05, 0.1 and 0.2 microg/mouse/day) significantly decreased both morphine-induced motor stimulation and locomotor sensitization.	Muscimol	46-54	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	22-27
17581962-4	2007	We show that the reversal potential of muscimol-induced current, E(GABA-A), was shifted toward depolarized potentials in axotomized neurons.	Muscimol	39-47	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	67-73
17212695-4	2007	Moreover, prior sustained exposure to muscimol significantly facilitated the subsequent expression of an astroglial marker protein in cells differentiated by ciliary neurotrophic factor (CNTF) toward an astroglial lineage, with a concomitant decrease in the neuronal marker protein expression, in an antagonist-sensitive manner on Western blotting analysis.	Muscimol	38-46	ciliary neurotrophic factor	Rattus norvegicus	158-185
17212695-4	2007	Moreover, prior sustained exposure to muscimol significantly facilitated the subsequent expression of an astroglial marker protein in cells differentiated by ciliary neurotrophic factor (CNTF) toward an astroglial lineage, with a concomitant decrease in the neuronal marker protein expression, in an antagonist-sensitive manner on Western blotting analysis.	Muscimol	38-46	ciliary neurotrophic factor	Rattus norvegicus	187-191
16624534-3	2007	Intra-CA1 administration of the GABA(A) receptor agonist, muscimol (0.25, 0.5 and 1 microg/rat) significantly inhibited the morphine (5 mg/kg, s.c.)-induced CPP.	Muscimol	58-66	carbonic anhydrase 1	Rattus norvegicus	6-9
17990949-10	2007	Treatment of microvascular endothelial cells with Hcy decreased GABA(A) receptor protein level, which was restored to its baseline level in the presence of GABA(A) receptor agonist, muscimol.	Muscimol	182-190	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	64-71
17990949-10	2007	Treatment of microvascular endothelial cells with Hcy decreased GABA(A) receptor protein level, which was restored to its baseline level in the presence of GABA(A) receptor agonist, muscimol.	Muscimol	182-190	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	156-163
16624534-6	2007	Furthermore, the muscimol-induced inhibition of morphine response was reversed by bicuculline (1 microg/rat, intra-CA1) administration.	Muscimol	17-25	carbonic anhydrase 1	Rattus norvegicus	115-118
16624534-7	2007	On the other hand, the bilateral intra-CA1 injections of muscimol (0.25, 0.5 and 1 microg/rat) or bicuculline (0.5, 1 and 2 microg/rat) significantly decreased the expression of morphine-induced CPP.	Muscimol	57-65	carbonic anhydrase 1	Rattus norvegicus	39-42
17049512-5	2006	Muscimol, a GABA(A) agonist, displays the same action as methyleugenol with respect to the formalin test and NMDA-induced behaviors.	Muscimol	0-8	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	12-19
17005618-4	2007	In head-fixed, sleeping zebra finches we find that injections of the GABA(A)-agonist muscimol into NIf lead to transient abolishment of premotor-like bursting activity in HVC neurons.	Muscimol	85-93	S100 calcium binding protein A9	Homo sapiens	99-102
17999204-8	2007	After knockdown, Ca2+ influx was suppressed as both NMDA and muscimol-stimulated Ca2+ permeability of the immature CA1 was blocked in ex-vivo slices measured with FURA-2AM optical dye imaging.	Muscimol	61-69	carbonic anhydrase 2	Rattus norvegicus	17-20
17999204-8	2007	After knockdown, Ca2+ influx was suppressed as both NMDA and muscimol-stimulated Ca2+ permeability of the immature CA1 was blocked in ex-vivo slices measured with FURA-2AM optical dye imaging.	Muscimol	61-69	carbonic anhydrase 2	Rattus norvegicus	81-84
17999204-8	2007	After knockdown, Ca2+ influx was suppressed as both NMDA and muscimol-stimulated Ca2+ permeability of the immature CA1 was blocked in ex-vivo slices measured with FURA-2AM optical dye imaging.	Muscimol	61-69	carbonic anhydrase 1	Rattus norvegicus	115-118
16844276-12	2006	Rofecoxib (1 mg/kg) or nimesulide (1 mg/kg) also enhanced the sub-protective effect of diazepam or muscimol showing GABAergic modulation of COX-2 inhibitors.	Muscimol	99-107	cytochrome c oxidase II, mitochondrial	Mus musculus	140-145
17156208-4	2006	Third, Per2 but not Per1 levels decreased 1 and 2 h after injection of the gamma-aminobutyric acid (GABA)(A) receptor agonist muscimol into the SCN during the subjective day.	Muscimol	126-134	period circadian regulator 2	Rattus norvegicus	7-11
17092492-5	2006	Both GABA antagonists failed to significantly affect orexin A-induced feeding, but muscimol significantly and dose dependently inhibited orexin A-induced feeding.	Muscimol	83-91	hypocretin neuropeptide precursor	Rattus norvegicus	137-145
17156208-5	2006	Fourth, muscimol also reduced the light-induced Per2 in the early subjective night, but Per1 induction by light was not significantly affected.	Muscimol	8-16	period circadian regulator 2	Rattus norvegicus	48-52
17156208-7	2006	As with light, muscimol alters circadian phase, and daytime phase alterations induced by muscimol are associated with significant decreases in Per2 mRNA.	Muscimol	89-97	period circadian regulator 2	Rattus norvegicus	143-147
16809007-5	2006	Orexin A affects local GABA release and we co-injected orexin A with a GABA agonist, muscimol, in each brain site.	Muscimol	85-93	hypocretin neuropeptide precursor	Rattus norvegicus	0-8
16809007-8	2006	Muscimol significantly and dose-dependently inhibited orexin A effects on time spent moving only when administered to the rostral lateral hypothalamic area.	Muscimol	0-8	hypocretin neuropeptide precursor	Rattus norvegicus	54-62
16977492-8	2006	Reversible inactivation of the entorhinal cortex through muscimol infusion produced deficits in STM and a selective and rapid decrease in hippocampal ERK2 activation.4.	Muscimol	57-65	mitogen-activated protein kinase 1	Homo sapiens	150-154
16930414-6	2006	Bilateral infusions of the GABA agonists baclofen and muscimol (1 microg/side) into nucleus accumbens of sensitized rats blocked cocaine-induced Fos expression and locomotor activity.	Muscimol	54-62	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	145-148
16777089-5	2006	Similar results were seen with another GABA(A) agonist, muscimol.	Muscimol	56-64	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	39-46
16407427-6	2006	Finally, to confirm a decrease in the availability of postsynaptic GABAA receptors, we tested the effects of BDNF on focal application of the GABAA agonist muscimol.	Muscimol	156-164	brain derived neurotrophic factor	Homo sapiens	109-113
16820022-5	2006	A significant suppression of Period 2 mRNA following microinjection of muscimol was not observed in free-running conditions.	Muscimol	71-79	period circadian regulator 2	Homo sapiens	29-37
16820022-6	2006	However, Period 2 mRNA was significantly reduced following muscimol treatment when animals were maintained under a light cycle and transferred to constant darkness 42 h prior to treatment.	Muscimol	59-67	period circadian regulator 2	Homo sapiens	9-17
16452257-8	2006	Field recordings in gabra5-/- CA3 pyramidal layer showed an increased network excitability that was decreased by the GABAR agonist muscimol at a concentration that restored the tonic inhibition of gabra5-/- PCs to the WT level without altering phasic inhibition.	Muscimol	131-139	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	Mus musculus	20-26
16452257-8	2006	Field recordings in gabra5-/- CA3 pyramidal layer showed an increased network excitability that was decreased by the GABAR agonist muscimol at a concentration that restored the tonic inhibition of gabra5-/- PCs to the WT level without altering phasic inhibition.	Muscimol	131-139	carbonic anhydrase 3	Mus musculus	30-33
16452257-8	2006	Field recordings in gabra5-/- CA3 pyramidal layer showed an increased network excitability that was decreased by the GABAR agonist muscimol at a concentration that restored the tonic inhibition of gabra5-/- PCs to the WT level without altering phasic inhibition.	Muscimol	131-139	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	Mus musculus	197-203
16407427-7	2006	Postsynaptic responses to muscimol were reduced after BDNF.	Muscimol	26-34	brain derived neurotrophic factor	Homo sapiens	54-58
16012340-3	2005	We show that stimulation of gamma-aminobutyric acid type A receptors, which is known to hyperpolarize orexin neurons, by muscimol or isoguvacine potently inhibits quinolinic acid cytotoxicity on orexin neurons.	Muscimol	121-129	hypocretin neuropeptide precursor	Homo sapiens	102-108
16412398-12	2006	In addition, altered KCC immunoreactivity induced by baclofen or muscimol may play an important role in maintaining or regulating inhibitory transmission during GABA receptor activation.	Muscimol	65-73	GABA type A receptor-associated protein	Homo sapiens	161-174
16168444-6	2006	Prior administration of GABA(A) receptor agonists muscimol (25 ng/rat, icv) and diazepam (0.5 mg/kg, ip) at subeffective doses significantly potentiated the hyperphagic effect of orexin-A (30 nM/rat, icv).	Muscimol	50-58	hypocretin neuropeptide precursor	Rattus norvegicus	179-187
16150468-8	2005	GABA and muscimol, an agonist of the GABA(A) receptor, also block neuronal death induced by Abeta in rat hippocampal and cortical neurons.	Muscimol	9-17	amyloid beta precursor protein	Rattus norvegicus	92-97
16125793-23	2005	We further observed that immunoreactivity for the calcium-binding protein, calbindin D(28K), is increased in the brains of pups simultaneously administered KA and muscimol as compared to either alone.	Muscimol	163-171	calbindin 1	Rattus norvegicus	75-84
16452685-5	2006	The main findings of these experiments were: (1) Arc activity-regulated cytoskeletal protein (Arc), an immediate-early gene (also termed Arg 3.1) and c-fos mRNA are induced in the hippocampus after a context exposure, or context plus shock experience, but not after an immediate shock; and (2) BLA inactivation with muscimol attenuated the increase in Arc and c-fos mRNA in the hippocampus associated with contextual fear conditioning but did not influence Arc mRNA associated with context exploration.	Muscimol	316-324	activity regulated cytoskeleton associated protein	Homo sapiens	137-144
16452685-5	2006	The main findings of these experiments were: (1) Arc activity-regulated cytoskeletal protein (Arc), an immediate-early gene (also termed Arg 3.1) and c-fos mRNA are induced in the hippocampus after a context exposure, or context plus shock experience, but not after an immediate shock; and (2) BLA inactivation with muscimol attenuated the increase in Arc and c-fos mRNA in the hippocampus associated with contextual fear conditioning but did not influence Arc mRNA associated with context exploration.	Muscimol	316-324	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	150-155
16632878-4	2006	Specific ligands, muscimol and baclofen, respectively, control Schwann-cell proliferation and expression of some specific myelin proteins (i.e., glycoprotein P0 and peripheral myelin protein 22 [PMP22]).	Muscimol	18-26	peripheral myelin protein 22	Homo sapiens	165-193
16632878-4	2006	Specific ligands, muscimol and baclofen, respectively, control Schwann-cell proliferation and expression of some specific myelin proteins (i.e., glycoprotein P0 and peripheral myelin protein 22 [PMP22]).	Muscimol	18-26	peripheral myelin protein 22	Homo sapiens	195-200
16378694-9	2006	In the current-clamp condition, a subset of large spontaneous excitatory postsynaptic potentials triggered action potentials, and muscimol greatly increased the frequency of spontaneous excitatory postsynaptic potential-triggered action potentials in postsynaptic CA3 pyramidal neurons.	Muscimol	130-138	carbonic anhydrase 3	Rattus norvegicus	264-267
16012340-3	2005	We show that stimulation of gamma-aminobutyric acid type A receptors, which is known to hyperpolarize orexin neurons, by muscimol or isoguvacine potently inhibits quinolinic acid cytotoxicity on orexin neurons.	Muscimol	121-129	hypocretin neuropeptide precursor	Homo sapiens	195-201
15921658-6	2005	In contrast, unilateral injections of muscimol into the AcbSh consistently increased Fos expression in several brain regions.	Muscimol	38-46	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	85-88
15896866-5	2005	In addition, pretreatment with muscimol (1microM) for 24h inhibited the Abeta (25-35) (10microM)-induced elevation of cytosolic Ca(2+) concentration ([Ca(2+)]c) and glutamate release, generation of reactive oxygen species (ROS), and caspase-3 activity in cultured neurons.	Muscimol	31-39	caspase 3	Rattus norvegicus	233-242
15921658-8	2005	Fos synthesis in the LH was increased only on the side of the brain ipsilateral to the muscimol injection.	Muscimol	87-95	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	0-3
15885255-4	2005	Although muscimol (GABA(A+)) (0.1, 0.5 and 1 microg/rat, intra-CA1) produced dose dependent increase in %OAT and a slight increase in %OAE, bicuculline (GABA(A-)), (1, 2 and 4 microg/rat, intra-CA1) failed to change the anxiety profile.	Muscimol	9-17	carbonic anhydrase 1	Rattus norvegicus	63-66
15776449-4	2005	In muscimol (GABA(A) receptor agonist) treated SS gerbils, expression levels of CBP were enhanced as compared with saline-treated SS gerbils.	Muscimol	3-11	centrin 1	Homo sapiens	80-83
16013446-8	2005	GABA, muscimol (a GABA(A) receptor agonist), and baclofen (a GABA(B) receptor agonist) increased 5-bromodeoxyuridine (BrdU) incorporation into ATDC5 cells.	Muscimol	6-14	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	18-25
15885255-4	2005	Although muscimol (GABA(A+)) (0.1, 0.5 and 1 microg/rat, intra-CA1) produced dose dependent increase in %OAT and a slight increase in %OAE, bicuculline (GABA(A-)), (1, 2 and 4 microg/rat, intra-CA1) failed to change the anxiety profile.	Muscimol	9-17	UDP glucuronosyltransferase family 1 member A6	Rattus norvegicus	153-175
15885255-4	2005	Although muscimol (GABA(A+)) (0.1, 0.5 and 1 microg/rat, intra-CA1) produced dose dependent increase in %OAT and a slight increase in %OAE, bicuculline (GABA(A-)), (1, 2 and 4 microg/rat, intra-CA1) failed to change the anxiety profile.	Muscimol	9-17	carbonic anhydrase 1	Rattus norvegicus	194-197
15987263-6	2005	In male PN14-17 SNR neurons, GABA(A)-receptor activation with muscimol causes depolarization and increments in intracellular calcium concentration and the expression of calcium regulated genes, such as KCC2.	Muscimol	62-70	solute carrier family 12 member 5	Rattus norvegicus	202-206
15987263-8	2005	However, in PN14-17 females, muscimol hyperpolarizes the SNR neurons, does not increase intracellular calcium, and decreases KCC2 mRNA expression.	Muscimol	29-37	solute carrier family 12 member 5	Rattus norvegicus	125-129
16009500-4	2005	Bilateral injections of muscimol (0.2 nmol/0.2 microl) into the lateral parabrachial nucleus strongly increased 0.3 M NaCl (20.3+/-7.2 vs. saline: 2.6+/-0.9 ml/180 min) without changing water intake induced by the treatment with the diuretic furosemide combined with low dose of the angiotensin converting enzyme inhibitor captopril s.c.	Muscimol	24-32	angiotensin I converting enzyme	Rattus norvegicus	283-312
16276116-6	2005	TM3 cells not only express GABA(A )receptor subunits, but also bind the GABA agonist [(3)H]muscimol with a binding affinity in the range reported for other endocrine cells (K(d) = 2.740 +/- 0.721 nM).	Muscimol	91-99	tropomyosin 1, alpha	Mus musculus	0-3
15504757-7	2004	VIP (1 nM) increased muscimol-evoked inhibitory currents by 36.4 +/- 8.7% in eight out of ten CA1 interneurones in the stratum radiatum.	Muscimol	21-29	vasoactive intestinal peptide	Homo sapiens	0-3
15708488-0	2005	Effects of injections of 8-hydroxy-2-(di-n-propylamino)tetralin or muscimol in the median raphe nucleus on c-fos mRNA in the rat brain.	Muscimol	67-75	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	107-112
15579158-3	2004	VGF(588-617)-induced penile erection was reduced by nitro(omega)-L-arginine methylester (L-NAME; 20 microg), by morphine (5 microg) and by muscimol (1 microg), but not by dizocilpine [(+)MK-801; 1 microg], nor by cis-flupenthixol (10 microg) given into the paraventricular nucleus 10 min before the VGF peptide.	Muscimol	139-147	VGF nerve growth factor inducible	Rattus norvegicus	0-3
16154278-3	2005	Muscimol (0.5 microM), a selective GABA(A) receptor agonist, increased SC-evoked EPSC amplitude and decreased paired-pulse ratio in the slice preparation, in addition, it facilitated spontaneous glutamate release on to mechanically dissociated CA1 pyramidal neurons in an external Ca2+-dependent manner.	Muscimol	0-8	carbonic anhydrase 1	Homo sapiens	244-247
16154278-3	2005	Muscimol (0.5 microM), a selective GABA(A) receptor agonist, increased SC-evoked EPSC amplitude and decreased paired-pulse ratio in the slice preparation, in addition, it facilitated spontaneous glutamate release on to mechanically dissociated CA1 pyramidal neurons in an external Ca2+-dependent manner.	Muscimol	0-8	carbonic anhydrase 2	Homo sapiens	281-284
15908130-2	2005	Bilateral intranuclear injections of CART peptide (55-102, 1 microg/microl/side) into the AcbSh decreased food intake with no change in locomotion activity and attenuated the orexigenic effect of the GABA(A) agonist muscimol (100 ng/microl/side) in male Sprague-Dawley rats.	Muscimol	216-224	CART prepropeptide	Rattus norvegicus	37-41
15570176-0	2004	NPY mediates the feeding elicited by muscimol injections into the nucleus accumbens shell.	Muscimol	37-45	neuropeptide Y	Rattus norvegicus	0-3
15570176-1	2004	Injections of muscimol into the nucleus accumbens shell (AcbSh) induce large increases in food intake in satiated rats and also activate neurons in a number of feeding-related brain regions, including NPY-containing neurons in the arcuate hypothalamic nucleus and cells in the paraventricular hypothalamic nucleus.	Muscimol	14-22	neuropeptide Y	Rattus norvegicus	201-204
15504757-7	2004	VIP (1 nM) increased muscimol-evoked inhibitory currents by 36.4 +/- 8.7% in eight out of ten CA1 interneurones in the stratum radiatum.	Muscimol	21-29	carbonic anhydrase 1	Homo sapiens	94-97
15364024-4	2004	Prior administration of GABA(A) receptor agonist muscimol or neurosteroid ALLO or progesterone, a precursor of ALLO or neurosteroidogenic drugs like FGIN 1-27, an agonist at the mitochondrial diazepam binding inhibitor receptor (MDR) or metyrapone, an 11beta-hydroxylase inhibitor, significantly potentiated the anticonvulsant effect of fluoxetine.	Muscimol	49-57	malic enzyme complex, mitochondrial	Mus musculus	178-227
15548199-10	2004	In muscimol treated animals, significantly fewer neurons expressed PV in the inhibited hemicortex, but as many CTB labelled corticospinal neurons were present as in controls, along with an equally large corticospinal projection from contralateral to the implant, significantly greater than in controls.	Muscimol	3-11	parvalbumin	Rattus norvegicus	67-69
15548199-10	2004	In muscimol treated animals, significantly fewer neurons expressed PV in the inhibited hemicortex, but as many CTB labelled corticospinal neurons were present as in controls, along with an equally large corticospinal projection from contralateral to the implant, significantly greater than in controls.	Muscimol	3-11	phosphate cytidylyltransferase 1B, choline	Rattus norvegicus	111-114
15525283-7	2004	In contrast, rats that had received muscimol injections into their mPFC and were subsequently restrained exhibited an increase in the number of Fos-positive cells in the DMH, medial amygdala, and medial nucleus tractus solitarius as compared to vehicle-injected rats that experienced restraint stress.	Muscimol	36-44	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	144-147
14725632-5	2004	Intra-accumbens shell muscimol treatment significantly increased the percentage of orexin/hypocretin-containing neurons expressing Fos in the lateral, but not medial, portion of the perifornical/lateral hypothalamic area.	Muscimol	22-30	hypocretin neuropeptide precursor	Rattus norvegicus	83-89
15193633-3	2004	These data agree with reduction of mIPSCs by muscimol in whole-cell recordings from CA3 pyramidal neurons.	Muscimol	45-53	carbonic anhydrase 3	Homo sapiens	84-87
15080900-5	2004	In situ hybridization showed that after injecting muscimol in the D2R-/- mice, the expression of enkephalin and immediate early gene, NGFI-A, was closely regulated with the locomotor activity regulated by GABAergic stimulation.	Muscimol	50-58	jun proto-oncogene	Mus musculus	112-127
15080900-5	2004	In situ hybridization showed that after injecting muscimol in the D2R-/- mice, the expression of enkephalin and immediate early gene, NGFI-A, was closely regulated with the locomotor activity regulated by GABAergic stimulation.	Muscimol	50-58	early growth response 1	Mus musculus	134-140
14764659-7	2004	GABA(A) receptor functional assays ((36)Cl(-) influx) supported our behavioral results; the actions of the GABA(A) agonists, THIP and muscimol, were reduced in the cerebellar membranes of fyn-null mutant mice.	Muscimol	134-142	Fyn proto-oncogene	Mus musculus	188-191
15129159-0	2004	FOS expression in orexin neurons following muscimol perfusion of preoptic area.	Muscimol	43-51	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	0-3
15129159-0	2004	FOS expression in orexin neurons following muscimol perfusion of preoptic area.	Muscimol	43-51	hypocretin neuropeptide precursor	Rattus norvegicus	18-24
15610187-20	2004	Higher KCC2 messenger RNA (mRNA) expression in female PN15 SNR neurons compared with males may be responsible for sex-related differences in muscimol-induced electrophysiologic responses.	Muscimol	141-149	solute carrier family 12 member 5	Rattus norvegicus	7-11
14725632-5	2004	Intra-accumbens shell muscimol treatment significantly increased the percentage of orexin/hypocretin-containing neurons expressing Fos in the lateral, but not medial, portion of the perifornical/lateral hypothalamic area.	Muscimol	22-30	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	131-134
14725632-8	2004	Muscimol treatment also markedly increased Fos expression in the arcuate nucleus, which connects reciprocally to the lateral/perifornical hypothalamic area.	Muscimol	0-8	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	43-46
14660012-2	2003	Exposure (48 and/or 96 h) of human embryonic kidney (HEK 293) cells stably expressing recombinant alpha1beta2gamma2s GABA(A) receptors for gamma-aminobutyric (GABA, 1 mM) and muscimol (100 microM), but not for diazepam (1 microM), enhanced the maximum number (B(max)) of [3H]flunitrazepam binding sites without affecting their affinity (K(d)).	Muscimol	175-183	adrenoceptor alpha 1D	Homo sapiens	98-115
15365220-2	2004	Using post mortem tissue from individuals diagnosed with schizophrenia (n=6) and control subjects (n=6), the density of GAT-1 was established by displacing [3H]GABA with muscimol, and for GAT-3 [3H]beta-alanine was used.	Muscimol	170-178	solute carrier family 6 member 1	Homo sapiens	120-125
15145088-3	2004	Inhibition of neurons in the rostral raphe pallidus (RPa) with microinjection of muscimol (6 mM, 60 nl) abolished the increases in BAT SNA and BAT temperature and reduced the tachycardia induced by disinhibition of DMH neurons.	Muscimol	81-89	snail family transcriptional repressor 1	Rattus norvegicus	135-138
14643840-5	2003	Prior administration of diazepam and muscimol that promote the function of GABA(A) receptors reversed the anxiogenic response and decreased food intake elicited by alpha-MSH.	Muscimol	37-45	proopiomelanocortin	Rattus norvegicus	164-173
12917381-0	2003	Different reactions of control and epileptic rats to administration of APV or muscimol on thalamic or CA3-induced CA1 responses.	Muscimol	78-86	carbonic anhydrase 3	Rattus norvegicus	102-105
12917381-0	2003	Different reactions of control and epileptic rats to administration of APV or muscimol on thalamic or CA3-induced CA1 responses.	Muscimol	78-86	carbonic anhydrase 1	Rattus norvegicus	114-117
12917381-8	2003	The duration of the PSP as well as the amplitude and number of spikes were reduced by administration of APV or muscimol into CA1 in both control and epileptic rats.	Muscimol	111-119	carbonic anhydrase 1	Rattus norvegicus	125-128
14552904-10	2003	In vivo muscimol administration acutely downregulated KCC2 mRNA expression whereas nifedipine had no effect.	Muscimol	8-16	solute carrier family 12 member 5	Rattus norvegicus	54-58
14508330-5	2003	RESULTS: Microinjection of either naloxone (an opioid receptor antagonist) or muscimol (a gamma-aminobutyric acid receptor type A agonist) into the ventrolateral periaqueductal gray area inhibited N2O-induced c-Fos expression in the spinal cord and pontine noradrenergic nuclei, particularly in the A7.	Muscimol	78-86	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	209-214
14508330-6	2003	Microinjection of either naloxone or muscimol into the A7 nuclei also inhibited N2O-induced c-Fos expression in the spinal cord and the N2O-induced antinociceptive effect by the plantar test.	Muscimol	37-45	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	92-97
14552904-11	2003	The lower expression of KCC2 mRNA in infantile male SNR neurons may explain why muscimol-induced depolarization and [Ca(2+)](i) increases occur only in males.	Muscimol	80-88	solute carrier family 12 member 5	Rattus norvegicus	24-28
14520599-4	2003	It is suggested that suppression of GnRH/LH release under muscimol treatment may result from activation of GABAA receptors on GnRH nerve terminals and through GABAA receptor mechanism activated beta-endorphinergic and dopaminergic neurons in the VEN/NI.	Muscimol	58-66	gonadotropin releasing hormone 1	Homo sapiens	36-40
12970075-20	2003	The GABA(A) receptor agonist muscimol (2 mg kg-1), on the other hand, produced a more pronounced hypothermia in GABA(B(1))-/-mice.	Muscimol	29-37	gamma-aminobutyric acid (GABA) B receptor, 1	Mus musculus	112-121
12970075-21	2003	In GABA(B(1))+/+ and GABA(B(1))+/- mice, muscimol induced sedation and reduced locomotor activity.	Muscimol	41-49	gamma-aminobutyric acid (GABA) B receptor, 1	Mus musculus	3-12
12970075-21	2003	In GABA(B(1))+/+ and GABA(B(1))+/- mice, muscimol induced sedation and reduced locomotor activity.	Muscimol	41-49	gamma-aminobutyric acid (GABA) B receptor, 1	Mus musculus	21-30
12970075-22	2003	However, when given to GABA(B(1))-/- mice, muscimol triggered periods of intense jumping and wild running.	Muscimol	43-51	gamma-aminobutyric acid (GABA) B receptor, 1	Mus musculus	23-32
14520599-4	2003	It is suggested that suppression of GnRH/LH release under muscimol treatment may result from activation of GABAA receptors on GnRH nerve terminals and through GABAA receptor mechanism activated beta-endorphinergic and dopaminergic neurons in the VEN/NI.	Muscimol	58-66	gonadotropin releasing hormone 1	Homo sapiens	126-130
14592672-4	2003	Muscimol reduced rearing responses in both control and 192 IgG-Sap-lesioned animals whereas reduced wall-rearing responses occurred in control animals only.	Muscimol	0-8	amyloid P component, serum	Rattus norvegicus	63-66
12904508-5	2003	Activation of GABA(A) receptors with muscimol produced a reduction in intracellular Cl(-) content, cell shrinkage, and a stimulation of NKCC1 activity.	Muscimol	37-45	solute carrier family 12 member 2	Rattus norvegicus	136-141
14499453-0	2003	Muscimol prevents long-lasting potentiation of dorsal horn field potentials in rats with chronic constriction injury exhibiting decreased levels of the GABA transporter GAT-1.	Muscimol	0-8	solute carrier family 6 member 12	Rattus norvegicus	169-174
12904508-6	2003	Muscimol also triggered an increase in intracellular Ca2+, which depended on NKCC1 activity.	Muscimol	0-8	solute carrier family 12 member 2	Rattus norvegicus	77-82
12732927-10	2003	Also muscimol, an agonist at GABAA receptors, enhanced the expression of the proenkephalin gene.	Muscimol	5-13	proenkephalin	Rattus norvegicus	77-90
12736179-4	2003	In the perifornical area, a significantly higher percentage of orexin neurons expressed Fos after muscimol compared with saline injection.	Muscimol	98-106	hypocretin neuropeptide precursor	Rattus norvegicus	63-69
12736179-4	2003	In the perifornical area, a significantly higher percentage of orexin neurons expressed Fos after muscimol compared with saline injection.	Muscimol	98-106	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	88-91
12781999-10	2003	In the current experiment, we documented that muscimol exposure on postnatal days 0 and 1 leads to fewer neurons in the male and female rat hippocampus (CA1, CA2/3, and dentate gyrus) on postnatal day 21.	Muscimol	46-54	carbonic anhydrase 1	Rattus norvegicus	153-156
12781999-10	2003	In the current experiment, we documented that muscimol exposure on postnatal days 0 and 1 leads to fewer neurons in the male and female rat hippocampus (CA1, CA2/3, and dentate gyrus) on postnatal day 21.	Muscimol	46-54	carbonic anhydrase 2	Rattus norvegicus	158-163
12623990-8	2003	Inhibition of neuronal function in the vicinity of the hypothalamic paraventricular nucleus, a possible source of innervation of the RVLM AT1R, by local injection with muscimol also produced a substantial decrease in MAP in DS-HNa rats but not in DS-LNa rats or DR rats.	Muscimol	168-176	angiotensin II receptor, type 1a	Rattus norvegicus	138-142
12752381-5	2003	This perfusion with muscimol at 50 micro m produced FOS-like immunoreactivity in 37% of the orexin neurons located in the tuberal part of the hypothalamus, whereas the FOS-like immunoreactivity was sparse in orexin neurons of the sleeping control rats (P = 0.001 by Mann-Whitney U-test).	Muscimol	20-28	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	52-55
12752381-5	2003	This perfusion with muscimol at 50 micro m produced FOS-like immunoreactivity in 37% of the orexin neurons located in the tuberal part of the hypothalamus, whereas the FOS-like immunoreactivity was sparse in orexin neurons of the sleeping control rats (P = 0.001 by Mann-Whitney U-test).	Muscimol	20-28	hypocretin neuropeptide precursor	Rattus norvegicus	92-98
12752381-5	2003	This perfusion with muscimol at 50 micro m produced FOS-like immunoreactivity in 37% of the orexin neurons located in the tuberal part of the hypothalamus, whereas the FOS-like immunoreactivity was sparse in orexin neurons of the sleeping control rats (P = 0.001 by Mann-Whitney U-test).	Muscimol	20-28	hypocretin neuropeptide precursor	Rattus norvegicus	208-214
12557004-6	2003	Using receptor autoradiography, [(3)H]AMPA and [(3)H]muscimol binding to excitatory AMPA and inhibitory GABA(A) receptors was analyzed in hippocampal subfields CA1, CA3 and dentate gyrus at recirculation intervals of 30 min, 8, 24, 48, 96 h and 3 weeks.	Muscimol	53-61	carbonic anhydrase 1	Homo sapiens	160-163
12557004-6	2003	Using receptor autoradiography, [(3)H]AMPA and [(3)H]muscimol binding to excitatory AMPA and inhibitory GABA(A) receptors was analyzed in hippocampal subfields CA1, CA3 and dentate gyrus at recirculation intervals of 30 min, 8, 24, 48, 96 h and 3 weeks.	Muscimol	53-61	carbonic anhydrase 3	Homo sapiens	165-168
12557004-7	2003	Postischemic hippocampal ligand binding to AMPA receptors remained unchanged at any time point investigated, but [(3)H]muscimol binding to GABA(A) receptors in CA1 neurons rendered tolerant to ischemia was up-regulated between 30 min and 48 h of recirculation.	Muscimol	119-127	carbonic anhydrase 1	Homo sapiens	160-163
12654529-5	2003	The suppressive influence of muscimol in the MPOA on GnRH release might be considered a net result of its direct inhibitory effect on GnRH release, indirect inhibitory influence on GnRH release through activation of the beta-endorphinergic system, and facilitation of GnRH neurons by increasing noradrenaline release.	Muscimol	29-37	gonadotropin releasing hormone 1	Homo sapiens	53-57
12654529-5	2003	The suppressive influence of muscimol in the MPOA on GnRH release might be considered a net result of its direct inhibitory effect on GnRH release, indirect inhibitory influence on GnRH release through activation of the beta-endorphinergic system, and facilitation of GnRH neurons by increasing noradrenaline release.	Muscimol	29-37	gonadotropin releasing hormone 1	Homo sapiens	134-138
12654529-5	2003	The suppressive influence of muscimol in the MPOA on GnRH release might be considered a net result of its direct inhibitory effect on GnRH release, indirect inhibitory influence on GnRH release through activation of the beta-endorphinergic system, and facilitation of GnRH neurons by increasing noradrenaline release.	Muscimol	29-37	gonadotropin releasing hormone 1	Homo sapiens	134-138
12654529-5	2003	The suppressive influence of muscimol in the MPOA on GnRH release might be considered a net result of its direct inhibitory effect on GnRH release, indirect inhibitory influence on GnRH release through activation of the beta-endorphinergic system, and facilitation of GnRH neurons by increasing noradrenaline release.	Muscimol	29-37	gonadotropin releasing hormone 1	Homo sapiens	134-138
12654502-0	2003	Exogenous brain-derived neurotrophic factor prevents postischemic downregulation of [3H]muscimol binding to GABA(A) receptors in the cortical penumbra.	Muscimol	88-96	brain-derived neurotrophic factor	Rattus norvegicus	10-43
12522168-12	2003	An increase in phosphorylation of NKCC1 was detected under both 10 mM [Cl(-)](o) and muscimol conditions.	Muscimol	85-93	solute carrier family 12 member 2	Homo sapiens	34-39
12543472-5	2003	Spinal muscimol significantly (10 microg/50 microl) reduced evoked Abeta-, Adelta- and C-fibre responses of spinal neurones in control rats (58+/-22% of control, P<0.05; 3+/-2% of control, P<0.001; and 8+/-7% of control, P<0.001; respectively).	Muscimol	7-15	amyloid beta precursor protein	Rattus norvegicus	67-72
12543472-9	2003	Following either sham surgery, or spinal nerve ligation, spinal muscimol inhibited Abeta-, Adelta- and C-fibre evoked responses of spinal neurones to a similar extent, however significant inhibitory effects on the post-discharge response were not observed in nerve injured rats.	Muscimol	64-72	amyloid beta precursor protein	Rattus norvegicus	83-88
12490572-8	2003	Deletion of either the alpha1 or beta2 subunits reduced the muscimol-stimulated 36Cl36 influx in cortical microsacs suggesting that these mutant mice have reduced number of functional brain GABAA receptors.	Muscimol	60-68	hemoglobin, beta adult minor chain	Mus musculus	33-38
12490572-8	2003	Deletion of either the alpha1 or beta2 subunits reduced the muscimol-stimulated 36Cl36 influx in cortical microsacs suggesting that these mutant mice have reduced number of functional brain GABAA receptors.	Muscimol	60-68	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	190-195
12617940-6	2003	Muscimol given 30 min before killing significantly increased the number of neurons exhibiting phosphorylated cyclic AMP response element binding protein in newborn male hypothalamus and CA1 hippocampus but decreased phosphorylated cyclic AMP response element binding protein in most brain regions in females.	Muscimol	0-8	carbonic anhydrase 1	Rattus norvegicus	186-189
12534969-7	2003	Voltage-sensitive Ca2+ channel blockers inhibited the muscimol-induced Ca2+ increase whereas tetrodotoxin had no effect, suggesting that stimulation of postsynaptic GABAA receptors depolarizes SCN neurons to increase Ca2+.	Muscimol	54-62	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	165-170
12927220-6	2003	Using bilateral local microinjections of the GABA(A) receptor agonist muscimol, we inactivated neurons originating from the central nucleus of the amygdala (CeA) or basolateral nucleus of the amygdala (BLA).	Muscimol	70-78	carcinoembryonic antigen gene family 4	Rattus norvegicus	157-160
12927220-8	2003	In rats treated with intra-CeA muscimol, however, the antinociceptive effect of WIN55,212-2 was significantly reduced.	Muscimol	31-39	carcinoembryonic antigen gene family 4	Rattus norvegicus	27-30
12927220-12	2003	In rats treated with intra-CeA muscimol, however, these effects of WIN55,212-2 were significantly reduced.	Muscimol	31-39	carcinoembryonic antigen gene family 4	Rattus norvegicus	27-30
12460246-11	2002	There was less apparent neuronal injury and CA3 and supragranular mossy fiber sprouting in hippocampi of animals receiving muscimol-containing particles than in animals that did not receive muscimol.	Muscimol	123-131	carbonic anhydrase 3	Rattus norvegicus	44-47
12486198-8	2002	Experiment 2 was designed to determine whether inactivation of the ACe with muscimol would attenuate the response of dLGN neurons in the awake rabbit to the presentation of acoustic, fear-arousing, conditioned stimuli.	Muscimol	76-84	angiotensin-converting enzyme	Oryctolagus cuniculus	67-70
12460246-12	2002	Hippocampi of animals that received 5 microg of encapsulated muscimol showed less supragranular sprouting than did those receiving 5 microg of unencapsulated muscimol, but showed no difference in cell loss or CA3 sprouting.	Muscimol	61-69	carbonic anhydrase 3	Rattus norvegicus	209-212
12053014-0	2002	[3H]muscimol binding to gamma-aminobutyric acid(A) receptors is upregulated in CA1 neurons of the gerbil hippocampus in the ischemia-tolerant state.	Muscimol	4-12	carbonic anhydrase 1	Homo sapiens	79-82
12456806-9	2002	In contrast, bath application of the GABA(A)R agonist muscimol transiently increased then suppressed firing; suppression persisted 4-15 min.	Muscimol	54-62	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	Mus musculus	37-45
12384238-11	2002	Similar to nicotinic agonists, gamma-aminobutyric acid receptor (GABA(A)) agonist muscimol (i.t.)	Muscimol	82-90	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	65-72
12384238-13	2002	The GABA(A) antagonists bicuculline and picrotoxin significantly blocked the analgesic effects of muscimol as well as that of (-)nicotine and (+)epibatidine.	Muscimol	98-106	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	4-11
12163549-13	2002	Both GABA and muscimol stimulated BDNF expression, and pretreatment with U0126 attenuated GABA-induced BDNF expression.	Muscimol	14-22	brain derived neurotrophic factor	Homo sapiens	34-38
12053014-7	2002	[3H]Muscimol binding to GABA(A) receptors in CA1 neurons was transiently but significantly increased after preconditioning but not after global ischemia with consecutive neuronal death.	Muscimol	4-12	carbonic anhydrase 1	Homo sapiens	45-48