PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
31852737-3	2020	We found that one of these compounds, (-)3,4-divanillyltetrahydrofuran (DVT), present in stinging nettle root extracts and used as a nutraceutical, binds SHBG with relatively low affinity.	3,4-divanillyltetrahydrofuran	38-70	sex hormone binding globulin	Homo sapiens	154-158
9461660-2	1998	(-)-3,4-Divanillyltetrahydrofuran (1) has the highest binding affinity (Ka = 3.2 +/- 1.7 x 10(6)M-1) of all lignans investigated so far; the reversibility of its binding and a double reciprocal plot suggest a competitive inhibition of the SHBG-DHT interaction.	3,4-divanillyltetrahydrofuran	0-33	sex hormone binding globulin	Homo sapiens	239-243