PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
32116757-13	2020	Also, our findings support the hypothesis that mechanosensitivity of TRPC6 channels modulates cytosolic calcium transients and SR calcium load.	sr calcium	127-137	transient receptor potential cation channel, subfamily C, member 6	Rattus norvegicus	69-74
10603985-3	1998	Experiments measuring tension transients in saponin-permeabilized cardiac muscles from genetically engineered mice under a variety of SR calcium loading conditions provide evidence of the functional alterations that can be achieved by manipulation of the degree of PLB inhibition of the calcium pump.	sr calcium	134-144	phospholamban	Mus musculus	265-268
8958128-8	1997	Exogenously added cyclic AMP-dependent protein kinase (A-PK) or calmodulin (CAM) increased SR calcium uptake activity.	sr calcium	91-101	calmodulin 1	Rattus norvegicus	64-74
8958128-8	1997	Exogenously added cyclic AMP-dependent protein kinase (A-PK) or calmodulin (CAM) increased SR calcium uptake activity.	sr calcium	91-101	calmodulin 1	Rattus norvegicus	76-79
30806861-10	2018	These results suggest that the abnormal increase in PLN in the ipsilateral fast-twitch fibers may be involved in decreased SERCA activity, SR calcium content, peak calcium transients, and contractile forces of denervated muscles.	sr calcium	139-149	phospholamban	Mus musculus	52-55
20029633-6	2009	Downregulation of RyR2 up to a certain degree is compensated by increased SR calcium content to normalize calcium sparks.	sr calcium	74-84	ryanodine receptor 2	Homo sapiens	18-22
21196188-8	2011	The redox state of RyR2 is altered in heart failure leading to enhanced RyR2 activity, which presumably contributes to decrease SR calcium content and induce other calcium release abnormalities observed in heart failure.	sr calcium	128-138	ryanodine receptor 2	Homo sapiens	19-23
21196188-8	2011	The redox state of RyR2 is altered in heart failure leading to enhanced RyR2 activity, which presumably contributes to decrease SR calcium content and induce other calcium release abnormalities observed in heart failure.	sr calcium	128-138	ryanodine receptor 2	Homo sapiens	72-76
22679139-4	2012	SR calcium uptake is mediated by a Ca(2+)-ATPase (SERCA2), whose activity is reversibly regulated by phospholamban (PLN).	sr calcium	0-10	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2	Homo sapiens	50-56
22679139-4	2012	SR calcium uptake is mediated by a Ca(2+)-ATPase (SERCA2), whose activity is reversibly regulated by phospholamban (PLN).	sr calcium	0-10	phospholamban	Homo sapiens	116-119
16740607-8	2006	SR calcium loading in the myofibres of MLP-null mice was similar to that in control myofibres when energy support was provided via Bound CK, but approximately 36% lower than controls when energy support was provided by mitochondrial (P < 0.05).	sr calcium	0-10	cysteine and glycine-rich protein 3	Mus musculus	39-42
19065046-5	2009	Whereas Nix ablation was protective in a mouse model of apoptotic cardiomyopathy, genetic correction of the decreased SR calcium content of Nix-null mice restored sensitivity to cell death and reestablished cardiomyopathy.	sr calcium	118-128	BCL2/adenovirus E1B interacting protein 3-like	Mus musculus	140-143
16061275-7	2006	SR calcium overload is shown to result in excitation of RyR lattice auto-oscillations with spontaneous RyR channel opening and closure.	sr calcium	0-10	ryanodine receptor 1	Homo sapiens	56-59
16061275-7	2006	SR calcium overload is shown to result in excitation of RyR lattice auto-oscillations with spontaneous RyR channel opening and closure.	sr calcium	0-10	ryanodine receptor 1	Homo sapiens	103-106
11025440-7	2000	Inhibition of SR calcium efflux selectively decreased MGP mRNA levels by 30-50% when using dantrolene, thapsigargin, or a dose of ryanodine shown to inactivate Ca(2+)-induced SR Ca(2+) release (CICR).	sr calcium	14-24	matrix Gla protein	Rattus norvegicus	54-57
15126052-11	2004	When cells were exposed to cyclopiazonic acid (CPA) to release SR calcium stores, P(o) increased slowly, then persisted at large values.	sr calcium	63-73	carboxypeptidase A1	Homo sapiens	47-50