PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21918689-6	2011	The nocodazole-induced prometaphase arrest was also abrogated by pre-treatment of cells with roscovitine, an inhibitor of cyclin-dependent kinases, or with cycloheximide, a protein synthesis inhibitor that was found to suppress cyclin B1 and Cdc2 up-regulation.	Cycloheximide	156-169	cyclin dependent kinase 1	Homo sapiens	242-246	
1340123-12	1992	The effects observed with antisense oligomers to p34cdc2 kinase are strikingly similar to what is observed when low concentrations of the drug cycloheximide are added to these cells at different times after serum stimulation; entry into S-phase is significantly inhibited when cycloheximide is added up to 12 hours postimulation.	Cycloheximide	143-156	cyclin dependent kinase 1	Homo sapiens	49-56	
1340123-12	1992	The effects observed with antisense oligomers to p34cdc2 kinase are strikingly similar to what is observed when low concentrations of the drug cycloheximide are added to these cells at different times after serum stimulation; entry into S-phase is significantly inhibited when cycloheximide is added up to 12 hours postimulation.	Cycloheximide	277-290	cyclin dependent kinase 1	Homo sapiens	49-56	
10956385-4	2000	The addition of cycloheximide inhibited the paclitaxel-induced increase in cdc2 protein level, further indicating that paclitaxel stimulates cdc2 synthesis.	Cycloheximide	16-29	cyclin dependent kinase 1	Homo sapiens	75-79	
10956385-4	2000	The addition of cycloheximide inhibited the paclitaxel-induced increase in cdc2 protein level, further indicating that paclitaxel stimulates cdc2 synthesis.	Cycloheximide	16-29	cyclin dependent kinase 1	Homo sapiens	141-145	
11120603-7	2001	CDC2 kinase activation was inhibited by cycloheximide.	Cycloheximide	40-53	cyclin dependent kinase 1	Homo sapiens	0-4	
11120603-8	2001	Furthermore, cycloheximide inhibited activation of CDK2:cyclin A, which normally precedes CDC2 kinase activation in caffeine-treated cells.	Cycloheximide	13-26	cyclin dependent kinase 1	Homo sapiens	90-94