PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10391681-1 1999 Fas ligation in the presence of cycloheximide induced Jun N-terminal kinase 1 (JNK1) and JNK2 phosphorylation, caspase activation and cell death in the IL-3-dependent cell line BAF3. Cycloheximide 32-45 interleukin 3 Homo sapiens 152-156 15459750-8 2004 Additionally, coincubation with cycloheximide blocked the mitotic effects of GM-CSF or IL-3, allowing only the apoptotic responses of TNF to persist. Cycloheximide 32-45 interleukin 3 Homo sapiens 87-91 12554354-5 2003 The IL-3-induced expression of CD13 was decreased in the presence of the protein-synthesis inhibitor cycloheximide (-8.8%). Cycloheximide 101-114 interleukin 3 Homo sapiens 4-8 1371965-10 1992 Cycloheximide completely inhibited the IL-3-induced expression of CD25, indicating the necessity for protein synthesis, and although most of the CD25+ cells were in G0/G1 phase, 25% of the cells were in S or G2M phase, indicating that receptor expression was not cell-cycle dependent. Cycloheximide 0-13 interleukin 3 Homo sapiens 39-43 8395533-0 1993 Interleukin-3 inhibits cycloheximide induction of C-jun mRNA in human monocytes: possible role for a serine/threonine phosphatase. Cycloheximide 23-36 interleukin 3 Homo sapiens 0-13 8395533-3 1993 The pluripotent colony stimulating factor interleukin-3 (IL-3) (10 ng/ml) is also a modest inducer of the c-jun gene in these cells; however, in combination with cycloheximide, IL-3 dramatically reduces the c-jun induction below levels induced by cycloheximide alone. Cycloheximide 162-175 interleukin 3 Homo sapiens 42-55 8395533-3 1993 The pluripotent colony stimulating factor interleukin-3 (IL-3) (10 ng/ml) is also a modest inducer of the c-jun gene in these cells; however, in combination with cycloheximide, IL-3 dramatically reduces the c-jun induction below levels induced by cycloheximide alone. Cycloheximide 162-175 interleukin 3 Homo sapiens 57-61 8395533-3 1993 The pluripotent colony stimulating factor interleukin-3 (IL-3) (10 ng/ml) is also a modest inducer of the c-jun gene in these cells; however, in combination with cycloheximide, IL-3 dramatically reduces the c-jun induction below levels induced by cycloheximide alone. Cycloheximide 247-260 interleukin 3 Homo sapiens 42-55 8395533-3 1993 The pluripotent colony stimulating factor interleukin-3 (IL-3) (10 ng/ml) is also a modest inducer of the c-jun gene in these cells; however, in combination with cycloheximide, IL-3 dramatically reduces the c-jun induction below levels induced by cycloheximide alone. Cycloheximide 247-260 interleukin 3 Homo sapiens 57-61 8395533-4 1993 This is a true inhibition and is not due to a change in temporal kinetics of induction because the suppression in the presence of IL-3 is observed at both 30 and 60 min after simultaneous addition of both IL-3 and cycloheximide. Cycloheximide 214-227 interleukin 3 Homo sapiens 130-134 8395533-5 1993 Preincubation of monocytes with 12.5 nM okadaic acid (a potent inhibitor of protein phosphatases 1 and 2A) and cycloheximide prior to addition of IL-3 restored the level of c-jun induction to that mediated by cycloheximide alone. Cycloheximide 209-222 interleukin 3 Homo sapiens 146-150 8395533-7 1993 These observations suggest that activation of protein serine/threonine phosphatase(s) underlies the ability of IL-3 to inhibit cycloheximide induction of c-jun in monocytes. Cycloheximide 127-140 interleukin 3 Homo sapiens 111-115 2049179-5 1991 The protein synthesis inhibitor, cycloheximide, enhances survival on IL3 removal, suggesting that death is an active process. Cycloheximide 33-46 interleukin 3 Homo sapiens 69-72