PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10098511-10 1999 Inhibition of protein synthesis by cycloheximide (CHX) drastically diminished the hCG-induced StAR protein content, indicating the requirement for on-going protein synthesis for hCG action. Cycloheximide 35-48 hypertrichosis 2 (generalised, congenital) Homo sapiens 82-85 10098511-10 1999 Inhibition of protein synthesis by cycloheximide (CHX) drastically diminished the hCG-induced StAR protein content, indicating the requirement for on-going protein synthesis for hCG action. Cycloheximide 50-53 hypertrichosis 2 (generalised, congenital) Homo sapiens 82-85 7956942-9 1994 When the cells were treated with the protein synthesis inhibitor cycloheximide (20 micrograms/ml) 20 min before stimulation of the cells with hCG, both basal and hCG-stimulated FS mRNA levels increased at 24 h, indicating stabilization of the transcripts. Cycloheximide 65-78 hypertrichosis 2 (generalised, congenital) Homo sapiens 142-145 7956942-9 1994 When the cells were treated with the protein synthesis inhibitor cycloheximide (20 micrograms/ml) 20 min before stimulation of the cells with hCG, both basal and hCG-stimulated FS mRNA levels increased at 24 h, indicating stabilization of the transcripts. Cycloheximide 65-78 hypertrichosis 2 (generalised, congenital) Homo sapiens 162-165 3455047-6 1987 However, actinomycin D and cycloheximide prevented the effect of hCG. Cycloheximide 27-40 hypertrichosis 2 (generalised, congenital) Homo sapiens 65-68 8392959-10 1993 The addition of cycloheximide or actinomycin D to the media did not affect the basal production of estradiol but completely blocked the bGH and hCG stimulation of the aromatization of exogenous testosterone to estradiol. Cycloheximide 16-29 hypertrichosis 2 (generalised, congenital) Homo sapiens 144-147 2829853-9 1988 These studies show that hCG and db cyclic AMP stimulation of MA-10 cells results in the rapid induction of cycloheximide-sensitive proteins located in the mitochondria which may be instrumental in the acute regulation of steroidogenesis. Cycloheximide 107-120 hypertrichosis 2 (generalised, congenital) Homo sapiens 24-27 4038724-2 1985 In this present study, we investigated the correlation between the preovulatory increase in progesterone and the periovulatory increase in plasminogen activator (PA) activities was completely suppressed with simultaneous injection with hCG of a minimum effective dose of cycloheximide to block ovulation completely. Cycloheximide 271-284 hypertrichosis 2 (generalised, congenital) Homo sapiens 236-239 3007125-11 1986 Cycloheximide and actinomycin D inhibit hCG-mediated and 8-BrcAMP-mediated down-regulation. Cycloheximide 0-13 hypertrichosis 2 (generalised, congenital) Homo sapiens 40-43 2410037-7 1985 Cycloheximide, at a dose of 0.1 mg/rat, was given at 12 h before hCG, immediately after hCG, and at 9 h after hCG. Cycloheximide 0-13 hypertrichosis 2 (generalised, congenital) Homo sapiens 65-68 2410037-7 1985 Cycloheximide, at a dose of 0.1 mg/rat, was given at 12 h before hCG, immediately after hCG, and at 9 h after hCG. Cycloheximide 0-13 hypertrichosis 2 (generalised, congenital) Homo sapiens 88-91 2410037-7 1985 Cycloheximide, at a dose of 0.1 mg/rat, was given at 12 h before hCG, immediately after hCG, and at 9 h after hCG. Cycloheximide 0-13 hypertrichosis 2 (generalised, congenital) Homo sapiens 88-91 3595728-5 1987 Emetine, cycloheximide and puromycin inhibited both basal and hCG stimulated protein synthesis as well as progesterone production in the cells. Cycloheximide 9-22 hypertrichosis 2 (generalised, congenital) Homo sapiens 62-65 3028794-12 1987 Since cycloheximide blocked the effects of PMA on hCG down-regulation, it is likely that the phorbol esters and 1-oleoyl-2-acetyl-sn-glycerol induce the synthesis of some proteins which blocked the recycling of internalized receptors. Cycloheximide 6-19 hypertrichosis 2 (generalised, congenital) Homo sapiens 50-53 15224149-7 2004 Verapamil (10 micromol/L), a Ca(2+) channel blocker, and cycloheximide (50 microg/ml), a protein synthesis inhibitor, reduced the immunostaining of c-Myb, and also lowered hCG-induced testosterone secretion in isolated rat Leydig cells. Cycloheximide 57-70 hypertrichosis 2 (generalised, congenital) Homo sapiens 172-175 11356667-12 2001 When granulosa cells were cultured in the presence of cycloheximide, a protein synthesis inhibitor, the inhibitory effects of hCG, FSK, and TPA on ERbeta mRNA levels were abolished. Cycloheximide 54-67 hypertrichosis 2 (generalised, congenital) Homo sapiens 126-129 6196179-3 1983 However, treatment with cycloheximide or puromycin before the hCG injection prevented the decrease in the activity of these enzymes by hCG. Cycloheximide 24-37 hypertrichosis 2 (generalised, congenital) Homo sapiens 62-65 6196179-3 1983 However, treatment with cycloheximide or puromycin before the hCG injection prevented the decrease in the activity of these enzymes by hCG. Cycloheximide 24-37 hypertrichosis 2 (generalised, congenital) Homo sapiens 135-138 6196179-5 1983 In correlation with the changes in these enzyme activities induced by hCG, the concentration of ovarian microsomal cytochrome P-450 decreased to barely detectable level after hCG treatment; this decrease was also prevented by pretreatment with cycloheximide. Cycloheximide 244-257 hypertrichosis 2 (generalised, congenital) Homo sapiens 70-73 6196179-5 1983 In correlation with the changes in these enzyme activities induced by hCG, the concentration of ovarian microsomal cytochrome P-450 decreased to barely detectable level after hCG treatment; this decrease was also prevented by pretreatment with cycloheximide. Cycloheximide 244-257 hypertrichosis 2 (generalised, congenital) Homo sapiens 175-178 6198267-5 1983 Addition of cycloheximide or Actinomycin D inhibited protein synthesis and RNA synthesis, respectively, and prevented the stimulation of hCG by sodium butyrate. Cycloheximide 12-25 hypertrichosis 2 (generalised, congenital) Homo sapiens 137-140 6295747-8 1983 Treatment with CHX increased the amounts of membrane-bound and internalized [125I]iodo-hCG and decreased the amounts of [125I]iodo-hCG that were degraded. Cycloheximide 15-18 hypertrichosis 2 (generalised, congenital) Homo sapiens 87-90 6295747-8 1983 Treatment with CHX increased the amounts of membrane-bound and internalized [125I]iodo-hCG and decreased the amounts of [125I]iodo-hCG that were degraded. Cycloheximide 15-18 hypertrichosis 2 (generalised, congenital) Homo sapiens 131-134