PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19754943-4 2009 METHODS: In this investigation was evaluated the effect of a previous vaccination with DNA-HSP65 on diabetes development induced by Streptozotocin (STZ). Streptozocin 132-146 heat shock protein 1 (chaperonin) Mus musculus 91-96 19754943-4 2009 METHODS: In this investigation was evaluated the effect of a previous vaccination with DNA-HSP65 on diabetes development induced by Streptozotocin (STZ). Streptozocin 148-151 heat shock protein 1 (chaperonin) Mus musculus 91-96 19754943-6 2009 RESULTS: DNA-HSP65 vaccination protected mice from STZ induced insulitis and this was associated with higher production of IL-10 in spleen and also in the islets. Streptozocin 51-54 heat shock protein 1 (chaperonin) Mus musculus 13-18 18351435-8 2008 RESULTS: Vaccination with p277 and hsp65 altered the pattern of STZ diabetes both in HDC-KO and WT animals, characterized by a transient increase followed by sustained reduction of blood sugar levels as compared to controls. Streptozocin 64-67 heat shock protein 1 (chaperonin) Mus musculus 35-40 10866061-11 2000 Both humoral and cellular immune response to HSP65 was more pronounced in streptozotocin-injected mice. Streptozocin 74-88 heat shock protein 1 (chaperonin) Mus musculus 45-50 10866061-12 2000 When challenged with HSP65 in vitro, splenocytes from streptozotocin-injected mice favored the production of the T-helper (TH)-1 cytokine gamma-interferon. Streptozocin 54-68 heat shock protein 1 (chaperonin) Mus musculus 21-26 8772717-0 1996 The hsp60 peptide p277 arrests the autoimmune diabetes induced by the toxin streptozotocin. Streptozocin 76-90 heat shock protein 1 (chaperonin) Mus musculus 4-9 8039607-8 1994 Antibodies and T-cells reactive to hsp60 (heat shock protein) were triggered by the low-dose STZ administration and persisted throughout the period that preceded clinical diabetes. Streptozocin 93-96 heat shock protein 1 (chaperonin) Mus musculus 35-40 8039607-10 1994 Finally, active immunization to hsp60 caused transient hyperglycemia by itself and also aggravated the hyperglycemia induced by low-dose STZ. Streptozocin 137-140 heat shock protein 1 (chaperonin) Mus musculus 32-37