PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14988235-4	2004	In hepatocytes, GKA1 and GKA2 stimulated glucose phosphorylation, glycolysis, and glycogen synthesis to a similar extent as sorbitol, a precursor of fructose 1-phosphate, which indirectly activates GK through promoting its dissociation from GKRP.	fructose-1-phosphate	149-169	glucokinase	Homo sapiens	16-18	
12647375-1	2002	Fructose-1-phosphate, the product of fructose phosphorylation by fructokinase, favours glucose phosphorylation by glucokinase, at the intervention of a regulatory protein.	fructose-1-phosphate	0-20	glucokinase	Homo sapiens	114-125	
9762360-1	1998	The compartmentation of glucokinase in the hepatocyte is regulated by the extracellular glucose concentration and by substrates that alter the concentration of fructose 1-phosphate in the hepatocyte.	fructose-1-phosphate	160-180	glucokinase	Homo sapiens	24-35	
9762360-4	1998	An increase in extracellular glucose concentration, within the range occurring in the portal vein in the absorptive state, or low concentrations of fructose or sorbitol (precursors of fructose 1-phosphate), cause the translocation of glucokinase from the nucleus to the cytoplasm and this is associated with a corresponding increase in glucose phosphorylation.	fructose-1-phosphate	184-204	glucokinase	Homo sapiens	234-245	
9762360-9	1998	Translocation of glucokinase from the nucleus to the cytoplasm in response to precursors of fructose 1-phosphate (which cause dissociation of glucokinase from the regulatory protein) is associated with stimulation of glucose phosphorylation, glycolysis and glycogen synthesis.	fructose-1-phosphate	92-112	glucokinase	Homo sapiens	17-28	
9762360-9	1998	Translocation of glucokinase from the nucleus to the cytoplasm in response to precursors of fructose 1-phosphate (which cause dissociation of glucokinase from the regulatory protein) is associated with stimulation of glucose phosphorylation, glycolysis and glycogen synthesis.	fructose-1-phosphate	92-112	glucokinase	Homo sapiens	142-153	
9230355-4	1997	Glucokinase regulatory protein gelled F-actin, and gelation was specifically inhibited by glucokinase and the regulatory protein effectors fructose-1-phosphate (F1P) and fructose-6-phosphate (F6P).	fructose-1-phosphate	139-159	glucokinase	Homo sapiens	90-101	
9230355-4	1997	Glucokinase regulatory protein gelled F-actin, and gelation was specifically inhibited by glucokinase and the regulatory protein effectors fructose-1-phosphate (F1P) and fructose-6-phosphate (F6P).	fructose-1-phosphate	161-164	glucokinase	Homo sapiens	90-101	
23957911-4	2013	Formation of the mammalian GCK-GKRP complex is stimulated by fructose 6-phosphate and antagonized by fructose 1-phosphate.	fructose-1-phosphate	101-121	glucokinase	Homo sapiens	27-30	
18199594-2	2008	Elevated glucose concentrations and precursors of fructose 1-phosphate (e.g., sorbitol) cause dissociation of glucokinase from GKRP and translocation to the cytoplasm.	fructose-1-phosphate	50-70	glucokinase	Homo sapiens	110-121	
10677361-3	2000	There was strong synergism on glucokinase translocation between effects of glucose analogues (glucosamine, 5-thioglucose, mannoheptulose) and sorbitol, a precursor of fructose 1-phosphate.	fructose-1-phosphate	167-187	glucokinase	Homo sapiens	30-41	
10677361-10	2000	The results favour a two-site model for glucokinase translocation involving either two glucose-binding sites or one binding-site for glucose and one for fructose 1-phosphate.	fructose-1-phosphate	153-173	glucokinase	Homo sapiens	40-51	
8299888-7	1994	Fructose probably acts through the fructose 1-phosphate dependent deinhibition of glucokinase activity.	fructose-1-phosphate	35-55	glucokinase	Homo sapiens	82-93	
24568320-6	2014	The affinity of GK for GKRP was decreased and binding co-operativity increased by glucose, fructose 1-phosphate and GKA, reflecting disruption of the GK-GKRP complex.	fructose-1-phosphate	91-111	glucokinase	Homo sapiens	16-18