PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27091112-1	2017	Heparanase is a beta-glucuronidase that cleaves sugar chains of heparan sulfate proteoglycans.	Sugars	48-53	heparanase	Homo sapiens	0-10	
17339837-7	2007	The aim of this review is to describe the current drug discovery status of small molecule, sugar and neutralising antibody inhibitors of heparanase enzyme activity.	Sugars	91-96	heparanase	Homo sapiens	137-147	
34677445-1	2021	Sugar-based molecules such as heparins or natural heparan sulfate polysaccharides have been developed and widely studied for controlling heparanase (HPSE) enzymatic activity, a key player in extracellular matrix remodelling during cancer pathogenesis.	Sugars	0-5	heparanase	Homo sapiens	149-153	
34677445-3	2021	Given their versatile properties, we hypothesized that sugar-based inhibitors may interfere with enzymatic but also non-enzymatic HPSE activities.	Sugars	55-60	heparanase	Homo sapiens	130-134	
20049646-4	2010	Heparanase is an enzyme which cleaves beta 1,4 D: -glucuronic bonds in sugar groups of HSPGs.	Sugars	71-76	heparanase	Homo sapiens	0-10	
27565180-12	2016	IMPLICATIONS: This study aims to target both the malignant brain tumor cells per se and their microenvironment by changing the level of an enzyme, HPSE, that breaks down modified sugar chains on cell surfaces and in the extracellular space.	Sugars	179-184	heparanase	Homo sapiens	147-151