PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25897643-6 2015 A fragment orbital analysis reveals a high degree of Mo-O(H)-N-O covalency that provides a pi-orbital pathway for one-electron transfer to the substrate and defines orbital constraints on the Mo-substrate geometry for productive catalysis in mARC and other pyranopterin molybdenum enzymes that catalyze this one-electron transformation. pyranopterin 257-269 activity regulated cytoskeletal-associated protein Mus musculus 242-246