PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18355628-7 2008 Conversely, induction of the HO pathway in the LC with heme-lysinate (7.6 nmol, intra-LC) intensified the hypothermic response to restraint, and this effect was prevented by pretreatment with ODQ (a sGC inhibitor; given intracerebroventricularly, 1.3 nmol). 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 192-195 sarcoglycan beta Homo sapiens 199-202 22429006-6 2012 Neuroprotection was abrogated upon cotreatment with a sGC inhibitor, ODQ, thus supporting activation of the NO/sGC/CREB signaling cascade by furoxans. 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 69-72 sarcoglycan beta Homo sapiens 54-57 22429006-6 2012 Neuroprotection was abrogated upon cotreatment with a sGC inhibitor, ODQ, thus supporting activation of the NO/sGC/CREB signaling cascade by furoxans. 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 69-72 sarcoglycan beta Homo sapiens 111-114 21605670-7 2011 The relaxation induced by SNP (but not TERPY) was significantly reduced by pretreatment with ODQ (sGC inhibitor). 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 93-96 sarcoglycan beta Homo sapiens 98-101 18769038-8 2008 Moreover, inhibiting soluble guanylate cyclase (sGC) with ODQ mimicked the effect of L-NAME and abolished the effect of H(2)O(2). 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 58-61 sarcoglycan beta Homo sapiens 48-51 18055633-6 2007 Inhibiting the main molecular target of NO, soluble guanylate cyclase, with ODQ reduced the cycle frequency of the rhythm, suggesting that NO mediated its effects via sGC and cyclic GMP. 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 76-79 sarcoglycan beta Homo sapiens 167-170 33975383-3 2022 EXPERIMENTAL APPROACH: We utilized HEK293 cells expressing sGC proteins to study the changes that occur regarding its heme content, heterodimer status, and sGCbeta protein partners when the cells were given oxidant ODQ or the NO donor NOC12 to inactivate sGC. 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 215-218 sarcoglycan beta Homo sapiens 59-62 11429384-4 2001 The sGC inhibitor ODQ (10(-6) M) or the sarcoplasmic Ca(2+)-ATPase thapsigargin (2x10(-6) M) markedly inhibited the relaxation induced by NO, SNAP and SNP. 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 18-21 sarcoglycan beta Homo sapiens 4-7 30179715-11 2018 Pre-incubation with NO scavengers (cPTIO and oxyhemoglobin) attenuated (P < 0.01 and P < 0.0001, respectively), and the sGC inhibitor ODQ completely abolished nitrite-mediated vasorelaxation, confirming the involvement of NO and sGC. 1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one 140-143 sarcoglycan beta Homo sapiens 126-129