PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21565247-0 2011 Arsenic trioxide-induced apoptosis in TM4 Sertoli cells: the potential involvement of p21 expression and p53 phosphorylation. Arsenic Trioxide 0-16 transformation related protein 53, pseudogene Mus musculus 105-108 33357454-6 2021 In cellular and mouse xenograft models, ATO reactivates mutant p53 for tumor suppression. Arsenic Trioxide 40-43 transformation related protein 53, pseudogene Mus musculus 63-66 20624968-4 2010 Arsenicals active in Hh pathway antagonism include arsenic trioxide (ATO), a curative agent in clinical use for acute promyelocytic leukemia (APL); in our studies, ATO inhibited growth of Hh pathway-driven medulloblastoma allografts derived from Ptch+/-p53-/- mice within a range of serum levels comparable to those achieved in treatment of human APL. Arsenic Trioxide 51-67 transformation related protein 53, pseudogene Mus musculus 253-256 20624968-4 2010 Arsenicals active in Hh pathway antagonism include arsenic trioxide (ATO), a curative agent in clinical use for acute promyelocytic leukemia (APL); in our studies, ATO inhibited growth of Hh pathway-driven medulloblastoma allografts derived from Ptch+/-p53-/- mice within a range of serum levels comparable to those achieved in treatment of human APL. Arsenic Trioxide 69-72 transformation related protein 53, pseudogene Mus musculus 253-256 20624968-4 2010 Arsenicals active in Hh pathway antagonism include arsenic trioxide (ATO), a curative agent in clinical use for acute promyelocytic leukemia (APL); in our studies, ATO inhibited growth of Hh pathway-driven medulloblastoma allografts derived from Ptch+/-p53-/- mice within a range of serum levels comparable to those achieved in treatment of human APL. Arsenic Trioxide 164-167 transformation related protein 53, pseudogene Mus musculus 253-256