PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31205918-0 2019 MARVELD1 attenuates arsenic trioxide-induced apoptosis in liver cancer cells by inhibiting reactive oxygen species production. Arsenic Trioxide 20-36 MARVEL domain containing 1 Homo sapiens 0-8 31205918-10 2019 Results: Here, we show that MARVELD1 enhances the therapeutic effects of epirubicin, while inducing the strong resistance of liver cancer cells to As2O3 treatment. Arsenic Trioxide 147-152 MARVEL domain containing 1 Homo sapiens 28-36 31205918-11 2019 We further demonstrate that the As2O3-induced apoptosis was inhibited by MARVELD1 overexpression (24 h Vector vs. MARVELD1 =30.58% vs. 17.41%, P<0.01; 48 h Vector vs. MARVELD1 =46.50% vs. 21.02%, P<0.01), possibly through inhibiting ROS production by enhancing TRXR1 expression. Arsenic Trioxide 32-37 MARVEL domain containing 1 Homo sapiens 73-81 31205918-11 2019 We further demonstrate that the As2O3-induced apoptosis was inhibited by MARVELD1 overexpression (24 h Vector vs. MARVELD1 =30.58% vs. 17.41%, P<0.01; 48 h Vector vs. MARVELD1 =46.50% vs. 21.02%, P<0.01), possibly through inhibiting ROS production by enhancing TRXR1 expression. Arsenic Trioxide 32-37 MARVEL domain containing 1 Homo sapiens 114-122 31205918-11 2019 We further demonstrate that the As2O3-induced apoptosis was inhibited by MARVELD1 overexpression (24 h Vector vs. MARVELD1 =30.58% vs. 17.41%, P<0.01; 48 h Vector vs. MARVELD1 =46.50% vs. 21.02%, P<0.01), possibly through inhibiting ROS production by enhancing TRXR1 expression. Arsenic Trioxide 32-37 MARVEL domain containing 1 Homo sapiens 114-122 31205918-14 2019 Conclusions: Our data identified a unique role of MARVELD1 in As2O3-induced apoptosis and As2O3 cancer therapy resistance. Arsenic Trioxide 62-67 MARVEL domain containing 1 Homo sapiens 50-58 31205918-14 2019 Conclusions: Our data identified a unique role of MARVELD1 in As2O3-induced apoptosis and As2O3 cancer therapy resistance. Arsenic Trioxide 90-95 MARVEL domain containing 1 Homo sapiens 50-58